DHHS:10.1126/science.286.5449.2453 DHHS:10.1126/science.288.5471.1653 DHHS:10.1126/science.341.6142.128-b DHHS:10.1126/science.1102443 DHHS:10.1126/science.1153632 DHHS:10.1126/science.1173712 DHHS:10.1126/science.1246448