FN Thomson Reuters Web of Science™ VR 1.0 PT J AU Anderson, CR Hibbard, DJ Buehrer, RM AF Anderson, Christopher R. Hibbard, Daniel J. Buehrer, R. Michael TI The Impact of Bandwidth on the Performance of DSSS Signals in Indoor Office Environments SO IEEE TRANSACTIONS ON WIRELESS COMMUNICATIONS LA English DT Article DE Propagation measurements; spreading bandwidth; Rake receiver; fading variance ID WIRELESS CHANNELS; MULTIPATH; MODEL AB This letter presents an empirical analysis of the impact of spreading bandwidth on fading performance of direct-sequence spread spectrum signals. Over 20000 measurements were recorded in an indoor office environment at chip rates of 25 MHz, 100 MHz, 225 MHz, 400 MHz, and 500 MHz. A continuous wave signal was also used to characterize the fading of narrowband signals. Three particular effects are examined as chip rate (i.e., bandwidth) increases: energy splintering due to temporal dispersion, reduction in the fading of the total received energy due to reduced multipath interaction and the fading reduction per resolvable component. The effects are characterized for line-of-sight and non-line-of-sight environments and are used to determine the BER performance of a BPSK system when operating in the presence of all three effects. The results are also compared with the theoretical relationship between signal energy variation and chip rate. The analysis demonstrates that the use of a chip rate greater than 225 MHz (or bandwidth greater than approximately 200 MHz) provides only minor improvements in fading performance in these environments. C1 [Anderson, Christopher R.] USN Acad, Wireless Measurements Grp, Annapolis, MD 21402 USA. [Hibbard, Daniel J.; Buehrer, R. Michael] Virginia Polytech Inst & State Univ, Wireless Virginia Tech, Blacksburg, VA 24062 USA. RP Anderson, CR (reprint author), USN Acad, Wireless Measurements Grp, Annapolis, MD 21402 USA. EM canderso@usna.edu NR 32 TC 1 Z9 2 U1 0 U2 6 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1536-1276 EI 1558-2248 J9 IEEE T WIREL COMMUN JI IEEE Trans. Wirel. Commun. PD SEP PY 2011 VL 10 IS 9 BP 2792 EP 2799 DI 10.1109/TWC.2011.062911.101352 PG 8 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA 851CQ UT WOS:000297246300002 ER PT J AU Amara, J AF Amara, Jomana TI Testing for stationarity using covariates: an application to purchasing power parity SO APPLIED ECONOMICS LETTERS LA English DT Article ID UNIT-ROOT; NULL HYPOTHESIS; EXCHANGE-RATES AB We examine the evidence for Purchasing Power Parity (PPP) using post-Bretton Woods exchange rate data for 20 industrialized countries. The two tests used are the covariate tests for stationarity where the null hypothesis of stationarity is tested against the unit root alternative. These tests are generalizations of existing univariate stationarity tests and improve the power of univariate tests by utilizing the information contained in related stationary covariates. We conclude that PPP holds for 17 out of the 20 countries tested. C1 USN, Def Resources Management Inst, Postgrad Sch, Monterey, CA 93943 USA. RP Amara, J (reprint author), USN, Def Resources Management Inst, Postgrad Sch, 699 Dyer Rd,Bldg 234, Monterey, CA 93943 USA. EM jhamara@nps.edu NR 16 TC 1 Z9 1 U1 1 U2 5 PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD PI ABINGDON PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND SN 1350-4851 J9 APPL ECON LETT JI Appl. Econ. Lett. PD SEP-OCT PY 2011 VL 18 IS 13-15 BP 1295 EP 1301 DI 10.1080/13504851.2010.534059 PG 7 WC Economics SC Business & Economics GA 838BZ UT WOS:000296262900018 ER PT J AU Proshutinsky, A Aksenov, Y Kinney, JC Gerdes, R Golubeva, E Holland, D Holloway, G Jahn, A Johnson, M Popova, E Steele, M Watanabe, E AF Proshutinsky, Andrey Aksenov, Yevgeny Kinney, Jaclyn Clement Gerdes, Ruediger Golubeva, Elena Holland, David Holloway, Greg Jahn, Alexandra Johnson, Mark Popova, Ekaterina Steele, Mike Watanabe, Eiji TI Recent Advances in Arctic Ocean Studies Employing Models from the Arctic Ocean Model Intercomparison Project SO OCEANOGRAPHY LA English DT Article ID SEA-ICE; CIRCULATION MODEL; WATER; BUDGET AB Observational data show that the Arctic Ocean has significantly and rapidly changed over the last few decades, which is unprecedented in the observational record. Air and water temperatures have increased, sea ice volume and extent have decreased, permafrost has thawed, storminess has increased, sea level has risen, coastal erosion has progressed, and biological processes have become more complex and diverse. In addition, there are socio-economic impacts of Arctic environmental change on Arctic residents and the world, associated with tourism, oil and gas exploration, navigation, military operations, trade, and industry. This paper discusses important results of the Arctic Ocean Model Intercomparison Project, which is advancing the role of numerical modeling in Arctic Ocean and sea ice research by stimulating national and international synergies for high-latitude research. C1 [Proshutinsky, Andrey] Woods Hole Oceanog Inst, Woods Hole, MA 02543 USA. [Aksenov, Yevgeny; Popova, Ekaterina] Natl Oceanog Ctr, Ocean Modeling & Forecasting Staff, Southampton, Hants, England. [Kinney, Jaclyn Clement] USN, Postgrad Sch, Monterey, CA USA. [Gerdes, Ruediger] Alfred Wegener Inst Polar & Marine Res, Sea Ice Phys Sect, D-2850 Bremerhaven, Germany. [Golubeva, Elena] Inst Computat Math & Math Geophys, Novosibirsk, Russia. [Holland, David] NYU, Ctr Atmosphere Ocean Sci, New York, NY USA. [Holloway, Greg] Inst Ocean Sci, Dept Fisheries & Oceans, Sidney, BC V8L 4B2, Canada. [Jahn, Alexandra] Natl Ctr Atmospher Res, Adv Study Program, Boulder, CO 80307 USA. [Johnson, Mark] Univ Alaska Fairbanks, Inst Marine Sci, Fairbanks, AK USA. [Steele, Mike] Univ Washington, Appl Phys Lab, Seattle, WA 98105 USA. [Watanabe, Eiji] Japan Agcy Marine Earth Sci & Technol, Kanagawa, Japan. RP Proshutinsky, A (reprint author), Woods Hole Oceanog Inst, Woods Hole, MA 02543 USA. EM aproshutinsky@whoi.edu RI Jahn, Alexandra/C-6545-2008; WATANABE, EIJI/C-2797-2009; Popova, Ekaterina/B-4520-2012; Golubeva, Elena/A-6606-2014 OI Jahn, Alexandra/0000-0002-6580-2579; Golubeva, Elena/0000-0001-6178-6789 FU National Science Foundation Office of Polar Programs [ARC-0804010, ARC-80630600, ARC-81284800, ARC-82486400] FX We gratefully acknowledge contributions from all AOMIP team members listed on the project Web site. This research is supported by the National Science Foundation Office of Polar Programs, awards ARC-0804010, ARC-80630600, ARC-81284800 and ARC-82486400. NR 33 TC 24 Z9 24 U1 0 U2 16 PU OCEANOGRAPHY SOC PI ROCKVILLE PA P.O. BOX 1931, ROCKVILLE, MD USA SN 1042-8275 J9 OCEANOGRAPHY JI Oceanography PD SEP PY 2011 VL 24 IS 3 SI SI BP 102 EP 113 PG 12 WC Oceanography SC Oceanography GA 826ZS UT WOS:000295394700016 ER PT J AU Fattibene, P Wieser, A Adolfsson, E Benevides, LA Brai, M Callens, F Chumak, V Ciesielski, B Della Monaca, S Emerich, K Gustafsson, H Hirai, Y Hoshi, M Israelsson, A Ivannikov, A Ivanov, D Kaminska, J Ke, W Lund, E Marrale, M Martens, L Miyazawa, C Nakamura, N Panzer, W Pivovarov, S Reyes, RA Rodzi, M Romanyukha, AA Rukhin, A Sholom, S Skvortsov, V Stepanenko, V Tarpan, MA Thierens, H Toyoda, S Trompier, F Verdi, E Zhumadilov, K AF Fattibene, P. Wieser, A. Adolfsson, E. Benevides, L. A. Brai, M. Callens, F. Chumak, V. Ciesielski, B. Della Monaca, S. Emerich, K. Gustafsson, H. Hirai, Y. Hoshi, M. Israelsson, A. Ivannikov, A. Ivanov, D. Kaminska, J. Ke, Wu Lund, E. Marrale, M. Martens, L. Miyazawa, C. Nakamura, N. Panzer, W. Pivovarov, S. Reyes, R. A. Rodzi, M. Romanyukha, A. A. Rukhin, A. Sholom, S. Skvortsov, V. Stepanenko, V. Tarpan, M. A. Thierens, H. Toyoda, S. Trompier, F. Verdi, E. Zhumadilov, K. TI The 4th international comparison on EPR dosimetry with tooth enamel Part 1: Report on the results SO RADIATION MEASUREMENTS LA English DT Article DE Electron paramagnetic resonance (EPR); Tooth enamel; Detection limit; Retrospective dosimetry ID SEMIPALATINSK REGION; QUANTIFICATION; LIMITS AB This paper presents the results of the 4th International Comparison of in vitro electron paramagnetic resonance dosimetry with tooth enamel, where the performance parameters of tooth enamel dosimetry methods were compared among sixteen laboratories from all over the world. The participating laboratories were asked to determine a calibration curve with a set of tooth enamel powder samples provided by the organizers. Nine molar teeth extracted following medical indication from German donors and collected between 1997 and 2007 were prepared and irradiated at the Helmholtz Zentrum Munchen. Five out of six samples were irradiated at 0.1, 0.2, 0.5, 1.0 and 1.5 Gy air kerma; and one unirradiated sample was kept as control. The doses delivered to the individual samples were unknown to the participants, who were asked to measure each sample nine times, and to report the EPR signal response, the mass of aliquots measured, and the parameters of EPR signal acquisition and signal evaluation. Critical dose and detection limit were calculated by the organizers on the basis of the calibration-curve parameters obtained at every laboratory. For calibration curves obtained by measuring every calibration sample three times, the mean value of the detection limit was 205 mGy, ranging from 56 to 649 mGy. The participants were also invited to provide the signal response and the nominal dose of their current dose calibration curve (wherever available), the critical dose and detection limit of which were also calculated by the organizers. (C) 2011 Elsevier Ltd. All rights reserved. C1 [Wieser, A.; Panzer, W.; Verdi, E.] Helmholtz Zentrum Muenchen, D-85764 Neuherberg, Germany. [Fattibene, P.; Della Monaca, S.] Ist Super Sanita, Dept Technol & Hlth, I-00162 Rome, Italy. [Adolfsson, E.; Gustafsson, H.; Israelsson, A.; Lund, E.] Linkoping Univ, SE-58185 Linkoping, Sweden. [Benevides, L. A.; Romanyukha, A. A.] USN, Dosimetry Ctr, Bethesda, MD 20889 USA. [Brai, M.; Marrale, M.] Univ Palermo, I-90128 Palermo, Italy. [Callens, F.; Martens, L.; Tarpan, M. A.; Thierens, H.] Univ Ghent, B-9000 Ghent, Belgium. [Chumak, V.; Sholom, S.] Res Ctr Radiat Med AMS, UA-04050 Kiev, Ukraine. [Ciesielski, B.; Emerich, K.; Kaminska, J.] Med Univ Gdansk, PL-80211 Gdansk, Poland. [Della Monaca, S.] Regina Elena Inst Canc Res, I-00144 Rome, Italy. [Emerich, K.] Dept Paediat Dent, PL-80208 Gdansk, Poland. [Hirai, Y.; Nakamura, N.] Radiat Effects Res Fdn, Minami Ku, Hiroshima 7320815, Japan. [Hoshi, M.; Rodzi, M.; Zhumadilov, K.] Hiroshima Univ, Minami Ku, Hiroshima 7348553, Japan. [Ivannikov, A.; Skvortsov, V.; Stepanenko, V.] Med Radiol Res Ctr, Obninsk, Kaluga Region, Russia. [Ivanov, D.] Inst Met Phys, Ekaterinburg 620041, Russia. [Ke, Wu] Beijing Inst Radiat Med, Beijing 100850, Peoples R China. [Miyazawa, C.] Ohu Univ, Dept Dent, Fukuyama, Hiroshima, Japan. [Pivovarov, S.; Rukhin, A.] Inst Nucl Phys, Alma Ata 050032, Kazakhstan. [Reyes, R. A.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA. [Toyoda, S.] Okayama Univ Sci, Okayama 7000005, Japan. [Trompier, F.] Inst Radioprotect & Surete Nucl, F-92262 Fontenay Aux Roses, France. RP Fattibene, P (reprint author), Ist Super Sanita, Dept Technol & Hlth, Viale Regina Elena 299, I-00162 Rome, Italy. EM paola.fattibene@iss.it RI Emerich, Katarzyna/B-7143-2013; Ivanov, Denis/J-3235-2013; Zhumadilov, Kassym/O-7356-2014; fattibene, paola/E-9041-2015; Chumak, Vadim/N-6960-2015; DELLA MONACA, SARA/E-9044-2015; MARRALE, MAURIZIO/I-9926-2014 OI TROMPIER, Francois/0000-0002-8776-6572; Ciesielski, Bartlomiej/0000-0001-8091-6040; Ivanov, Denis/0000-0001-6757-5587; Zhumadilov, Kassym/0000-0002-0205-4585; fattibene, paola/0000-0002-8204-0414; Chumak, Vadim/0000-0001-6045-9356; DELLA MONACA, SARA/0000-0002-3109-9344; MARRALE, MAURIZIO/0000-0002-0091-3243 FU EC project SOUL [FIP6R-516478] FX This work was supported by the EC project SOUL under the contract FIP6R-516478. The views expressed in this paper are those of the authors and do not necessarily reflect the official policy or position of the U.S. Department of the Navy, U.S. Department of Defense, or the U.S. Government. Ms. Monica Brocco is acknowledged for the linguistic revision of the manuscript. P.F. is grateful to Ms.Vanessa De Coste for her relevant technical support. NR 16 TC 23 Z9 24 U1 0 U2 13 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 1350-4487 J9 RADIAT MEAS JI Radiat. Meas. PD SEP PY 2011 VL 46 IS 9 SI SI BP 765 EP 771 DI 10.1016/j.radmeas.2011.05.001 PG 7 WC Nuclear Science & Technology SC Nuclear Science & Technology GA 835MA UT WOS:000296039300007 ER PT J AU Romanyukha, A Trompier, F Reyes, RA Melanson, MA AF Romanyukha, Alex Trompier, Francois Reyes, Ricardo A. Melanson, Mark A. TI EPR measurements of fingernails in Q-band SO RADIATION MEASUREMENTS LA English DT Article DE EPR dosimetry; Fingernails; Q-band; Accidental dosimetry; Radiation dosimetry ID ELECTRON-PARAMAGNETIC-RESONANCE; DOSIMETRY; RADICALS AB Results of a feasibility study for the use of the Q-band EPR measurements of fingernails are presented. Details of the first protocol developed for Q-band (34 GHz) EPR dose measurements in fingernails and preliminary results of a dosimetry study in comparison with the commonly-used X-band (9 GHz) are reported. It was found that 1-5 mg sample mass was sufficient for EPR measurements in fingernails in the Q-band, which is significantly less than the 15-30 mg needed for the X-band. This finding makes it possible to obtain sufficient fingernail sample for dose measurements, practically from every finger of any person. Another finding was that the spectral resolution of the mechanically-induced signal (MIS) and radiation-induced signal (RIS) in the Q-band was significantly better than in the X-band. The RIS and MIS in the Q-band spectrum have a more complex structure than in the X-band, which potentially offers the possibility to do dose measurements in fingernails without treatment and immediately after clipping. These findings and recent results related to fingernail dosimetry in the Q-band and its perspectives are discussed here. Published by Elsevier Ltd. C1 [Romanyukha, Alex] USN, Dosimetry Ctr, Bethesda, MD 20084 USA. [Trompier, Francois] Inst Radioprotect & Surete Nucl, Fontenay Aux Roses, France. [Reyes, Ricardo A.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA. [Melanson, Mark A.] Armed Forces Radiobiol Res Inst, Bethesda, MD USA. RP Romanyukha, A (reprint author), USN, Dosimetry Ctr, Bethesda, MD 20084 USA. EM Alexander.Romanyukha@med.navy.mil OI TROMPIER, Francois/0000-0002-8776-6572 FU U.S. Department of Defense; IRSN FX The study was funded through U.S. Department of Defense operational and maintenance budget and IRSN budget. The funding sources did not play any role in this study design, the collection, analysis and interpretation of data. The views expressed in this paper are those of the authors and do not reflect the official policy or position of the Navy and Marine Corps Public Health Center, Navy Bureau of Medicine and Surgery, Department of the Navy, Department of Defense, or the U.S. Government. NR 10 TC 12 Z9 13 U1 0 U2 5 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 1350-4487 J9 RADIAT MEAS JI Radiat. Meas. PD SEP PY 2011 VL 46 IS 9 SI SI BP 888 EP 892 DI 10.1016/j.radmeas.2011.04.004 PG 5 WC Nuclear Science & Technology SC Nuclear Science & Technology GA 835MA UT WOS:000296039300030 ER PT J AU Nguyen, HD Galitz, MS Clarke, DD AF Nguyen, Huong D. Galitz, Michael S. Clarke, Douglas D. TI Untitled SO ENDOCRINE PRACTICE LA English DT Editorial Material ID ANTERIOR MEDIASTINAL MASS; GRAVES-DISEASE C1 [Nguyen, Huong D.; Galitz, Michael S.; Clarke, Douglas D.] USN, Div Endocrinol, Med Ctr Portsmouth, Portsmouth, VA 23708 USA. RP Nguyen, HD (reprint author), USN, Div Endocrinol, Med Ctr Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA 23708 USA. EM hdnguyen55@hotmail.com NR 3 TC 1 Z9 1 U1 0 U2 0 PU AMER ASSOC CLINICAL ENDOCRINOLOGISTS PI JACKSONVILLE PA 245 RIVERSIDE AVENUE, STE 200, JACKSONVILLE, FL 32202 USA SN 1530-891X J9 ENDOCR PRACT JI Endocr. Pract. PD SEP-OCT PY 2011 VL 17 IS 5 BP 833 EP 833 DI 10.4158/EP11118.VV PG 1 WC Endocrinology & Metabolism SC Endocrinology & Metabolism GA 838TJ UT WOS:000296314800023 PM 21803716 ER PT J AU Santillan, ST Virgin, LN AF Santillan, S. T. Virgin, L. N. TI Numerical and experimental analysis of the static behavior of highly deformed risers SO OCEAN ENGINEERING LA English DT Article DE Geometric nonlinearity; Elastica; Finite differences; Flexible riser ID VIBRATION; OSCILLATIONS; CABLES AB This paper models a slender, flexible structure used as a drill string or riser in the offshore oil and gas industry that connects the well-head with a floating control vessel. These systems are used in deep-water drilling applications and present considerable design challenges due to their extreme flexibility and susceptibility to buckling and vibration. Two typical configurations are used (Bai and Bai, 2005), with a common feature involving the attachment of a buoy designed to relieve some of the axial forces acting on the riser, especially at the attachment points. Previous work by the authors studied numerical results of small-amplitude vibrations and two other equilibrium configurations using parameter values that closely resemble the full-scale application (Santillan et al., 2008). Here, two new configurations are considered, and experiments are designed and conducted to verify these equilibrium results. (C) 2011 Elsevier Ltd. All rights reserved. C1 [Virgin, L. N.] Duke Univ, Durham, NC 27708 USA. [Santillan, S. T.] USN Acad, Dept Mech Engn, Annapolis, MD 21402 USA. RP Virgin, LN (reprint author), Duke Univ, Durham, NC 27708 USA. EM l.virgin@duke.edu FU ONR [000141-0W-X2-1-287] FX This work has been supported by Dr. Kelly Cooper under ONR Grant 000141-0W-X2-1-287. NR 21 TC 13 Z9 17 U1 2 U2 12 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0029-8018 J9 OCEAN ENG JI Ocean Eng. PD SEP PY 2011 VL 38 IS 13 BP 1397 EP 1402 DI 10.1016/j.oceaneng.2011.06.009 PG 6 WC Engineering, Marine; Engineering, Civil; Engineering, Ocean; Oceanography SC Engineering; Oceanography GA 831ET UT WOS:000295712200004 ER PT J AU Tessarin, S Mikitchuk, D Doron, R Stambulchik, E Kroupp, E Maron, Y Hammer, DA Jacobs, VL Seely, JF Oliver, BV Fisher, A AF Tessarin, S. Mikitchuk, D. Doron, R. Stambulchik, E. Kroupp, E. Maron, Y. Hammer, D. A. Jacobs, V. L. Seely, J. F. Oliver, B. V. Fisher, A. TI Beyond Zeeman spectroscopy: Magnetic-field diagnostics with Stark-dominated line shapes SO PHYSICS OF PLASMAS LA English DT Article AB A recently suggested spectroscopic approach for magnetic-field determination in plasma is employed to measure magnetic fields in an expanding laser-produced plasma plume in an externally applied magnetic field. The approach enables the field determination in a diagnostically difficult regime for which the Zeeman-split patterns are not resolvable, as is often encountered under the conditions characteristic of high-energy-density plasmas. Here, such conditions occur in the high-density plasma near the laser target, due to the dominance of Stark broadening. A pulsed-power system is used to generate magnetic fields with a peak magnitude of 25 T at the inner-electrode surface in a coaxial configuration. An aluminum target attached to the inner electrode surface is then irradiated by a laser beam to produce the expanding plasma that interacts with the applied azimuthal magnetic field. A line-shape analysis of the Al III 4s-4p doublet (5696 and 5722 angstrom) enables the simultaneous determination of the magnetic field and the electron density. The measured magnetic fields are generally found to agree with those expected in a vacuum based on the pulsed-power system current. Examples of other transitions that can be used to diagnose a wide range of plasma and magnetic field parameters are presented. (C) 2011 American Institute of Physics. [doi:10.1063/1.3625555] C1 [Tessarin, S.; Mikitchuk, D.; Doron, R.; Stambulchik, E.; Kroupp, E.; Maron, Y.] Weizmann Inst Sci, Fac Phys, IL-76100 Rehovot, Israel. [Hammer, D. A.] Cornell Univ, Plasma Studies Lab, Ithaca, NY 14853 USA. [Jacobs, V. L.; Seely, J. F.] USN, Res Lab, Washington, DC 20375 USA. [Oliver, B. V.] Sandia Natl Labs, Albuquerque, NM 87185 USA. [Fisher, A.] Technion Israel Inst Technol, Fac Phys, Haifa, Israel. RP Doron, R (reprint author), Weizmann Inst Sci, Fac Phys, IL-76100 Rehovot, Israel. EM ramy.doron@weizmann.ac.il RI Stambulchik, Evgeny/K-1816-2012; Doron, Ramy/I-2064-2013 OI Stambulchik, Evgeny/0000-0002-7100-8793; FU U.S.-Israel Bi-national Science Foundation (BSF); NRL (USA) [N173-09-2-C010]; National Nuclear Security Administration under DOE [DE-FC03-02NA00057]; U.S. Office of Naval Research FX The authors are grateful to R. W. Lee and K. Tsigutkin for their valuable suggestions and to P. Meiri for his skilled technical assistance. This work was supported in part by the U.S.-Israel Bi-national Science Foundation (BSF) and by NRL (USA), Contract number N173-09-2-C010. D.A.H. was partially supported by the Stewardship Sciences Academic Alliances program of the National Nuclear Security Administration under DOE Cooperative Agreement No. DE-FC03-02NA00057. V.L.J. was partially supported by the U.S. Office of Naval Research. NR 8 TC 3 Z9 3 U1 0 U2 7 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 1070-664X J9 PHYS PLASMAS JI Phys. Plasmas PD SEP PY 2011 VL 18 IS 9 AR 093301 DI 10.1063/1.3625555 PG 9 WC Physics, Fluids & Plasmas SC Physics GA 829XY UT WOS:000295621300058 ER PT J AU Hashemi, N Erickson, JS Golden, JP Ligler, FS AF Hashemi, Nastaran Erickson, Jeffrey S. Golden, Joel P. Ligler, Frances S. TI Optofluidic characterization of marine algae using a microflow cytometer SO BIOMICROFLUIDICS LA English DT Article DE band-pass filters; biological techniques; bioMEMS; bio-optics; fluorescence; light scattering; marine pollution; microchannel flow; microorganisms; molecular biophysics; optical fibres; optical filters; photomultipliers; proteins ID FLOW-CYTOMETRY; SHEATH FLOW; PHYTOPLANKTON; FLUORESCENCE; PATTERNS; CLIMATE; DIATOM AB The effects of global warming, pollution in river effluents, and changing ocean currents can be studied by characterizing variations in phytoplankton populations. We demonstrate the design and fabrication of a Microflow Cytometer for characterization of phytoplankton. Guided by chevron-shaped grooves on the top and bottom of a microfluidic channel, two symmetric sheath streams wrap around a central sample stream and hydrodynamically focus it in the center of the channel. The lasers are carefully chosen to provide excitation light close to the maximum absorbance wavelengths for the intrinsic fluorophores chlorophyll and phycoerythrin, and the excitation light is coupled to the flow cytometer through the use of an optical fiber. Fluorescence and light scatter are collected using two multimode optical fibers placed at 90-degree angles with respect to the excitation fiber. Light emerging from these collection fibers is directed through optical bandpass filters into photomultiplier tubes. The cytometer measured the optical and side scatter properties of Karenia b., Synechococcus sp., Pseudo-Nitzchia, and Alexandrium. The effect of the sheath-to-sample flow-rate ratio on the light scatter and fluorescence of these marine microorganisms was investigated. Reducing the sample flow rate from 200 mu L/min to 10 mu L/min produced a more tightly focused sample stream and less heterogeneous signals. (C) 2011 American Institute of Physics. [doi:10.1063/1.3608136] C1 [Hashemi, Nastaran; Erickson, Jeffrey S.; Golden, Joel P.; Ligler, Frances S.] USN, Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. RP Ligler, FS (reprint author), USN, Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. EM Frances.ligler@nrl.navy.mil RI Hashemi, Nastaran/A-7645-2012; Erickson, Jeffrey/F-6273-2011 OI Hashemi, Nastaran/0000-0001-8921-7588; FU ONR/NRL FX This work was supported by ONR/NRL 6.2 work unit 69-6339. Nastaran Hashemi is an American Society for Engineering Education (ASEE) Postdoctoral Fellow. The authors thank Dr. Alan Weidemann (Naval Research Laboratory, Stennis, MI) and Dr. Lisa Hilliard (National Oceanic and Atmospheric Administration, Charleston, SC) for their assistance with this project. The views expressed here are those of the authors and do not represent opinion or policy of the U.S. Navy or Department of Defense. NR 30 TC 45 Z9 45 U1 2 U2 56 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 1932-1058 J9 BIOMICROFLUIDICS JI Biomicrofluidics PD SEP PY 2011 VL 5 IS 3 AR 032009 DI 10.1063/1.3608136 PG 9 WC Biochemical Research Methods; Biophysics; Nanoscience & Nanotechnology; Physics, Fluids & Plasmas SC Biochemistry & Molecular Biology; Biophysics; Science & Technology - Other Topics; Physics GA 829XE UT WOS:000295618500011 PM 22662031 ER PT J AU Arkes, J AF Arkes, Jeremy TI Recessions and the participation of youth in the selling and use of illicit drugs SO INTERNATIONAL JOURNAL OF DRUG POLICY LA English DT Article DE Drug use; Cannabis; Youth; Adolescent; Recessions; Economic crisis ID ECONOMIC-CONDITIONS; YOUNG ADULTHOOD; SUBSTANCE USE; CRIME; ADOLESCENCE; POPULATION; OUTCOMES; MARKETS; ABUSE AB Background: There has been limited research on how recessions (or more generally, the strength of the economy) affect drug use and the related outcome of drug selling. This is especially important, given the current economic crisis. This paper aims to use a conceptual framework, previous research, and new research to predict how the current economic crisis may be affecting youth drug selling and drug use. Methods: A conceptual framework to understand how a recession could affect youth drug selling and drug use is presented, along with a review of the literature on empirical investigations on how the strength of the economy affects these behaviours among teenagers. In addition, new analyses for young adults are presented. Results: The conceptual framework postulates that a recession would have direct positive effects on the prevalence of youth drug selling but ambiguous direct effects on youth drug use. The conceptual framework also postulates that drug selling and drug use are inter-connected at the individual level and the aggregate level. Thus, any effect of a recession on one would likely affect the other in the same direction. The limited empirical evidence indicates that both drug selling and drug use among youth are higher when the economy is weaker. Conclusions: The current economic crisis will likely increase both youth drug selling and drug use relative to what they would have otherwise been. Published by Elsevier B.V. C1 USN, Grad Sch Business & Publ Policy, Postgrad Sch, Monterey, CA 93943 USA. RP Arkes, J (reprint author), USN, Grad Sch Business & Publ Policy, Postgrad Sch, 555 Dyer Rd, Monterey, CA 93943 USA. EM arkes@nps.edu NR 26 TC 10 Z9 10 U1 2 U2 16 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0955-3959 J9 INT J DRUG POLICY JI Int. J. Drug Policy PD SEP PY 2011 VL 22 IS 5 BP 335 EP 340 DI 10.1016/j.drugpo.2011.03.001 PG 6 WC Substance Abuse SC Substance Abuse GA 831WH UT WOS:000295761300003 PM 21482093 ER PT J AU Gross, ML Beckstead, MW AF Gross, Matthew L. Beckstead, Merrill W. TI Steady-State Combustion Mechanisms of Ammonium Perchlorate Composite Propellants SO JOURNAL OF PROPULSION AND POWER LA English DT Article ID VORTICITY-VELOCITY FORMULATION; FLAMES; FLOWS AB The flame structures emanating from a mixture of ammonium perchlorate (AP) and hydroxy-terminated-polybutadiene (HTPB) have been calculated over a range of pressures and AP particle sizes using high-fidelity simulations. The calculated AP composite propellant flame structure consists of three premixed flames (AP monopropellant flame, homogenized-binder flame, and primary flame) and a diffusion flame. The variations in this flame structure, based on pressure and particle size, account for AP's unique combustion properties. As pressure is increased, the three premixed flames draw closer to the surface, increasing the propellant burning rate. However, the diffusion flame is forced farther into the gas phase, decreasing the propellant burning rate. This dichotomy creates large variations in how AP composite propellants burn at different pressures. Three regions of combustion have been calculated for AP composite propellants: the AP monopropellant limit, the diffusion flame region, and the premixed limit. The premixed limit represents the maximum burning rate, and the AP monopropellant limit represents the minimum burning rate. AP particle size and pressure dictate the region of combustion, as these parameters greatly affect the flame structure. A thorough explanation of AP's pressure and particle-size effects with regard to a propellant's burning rate is presented. Propellant burning rates and premixed cutoff diameters are predicted for an AP/HTPB system. The importance of correctly representing the homogenized binder in AP/HTPB propellant combustion simulations is also discussed. C1 [Gross, Matthew L.] USN, Air Warfare Ctr, Weap Div, China Lake, CA 93555 USA. [Beckstead, Merrill W.] Brigham Young Univ, Dept Chem Engn, Provo, UT 84602 USA. FU Naval Air Systems Command (NAVAIR) In-House Laboratory Independent Research (ILIR) FX This work was sponsored by the Naval Air Systems Command (NAVAIR) In-House Laboratory Independent Research (ILIR) program, managed at the Office of Naval Research by the N-STAR program (Naval Research-Science and Technology for America's Readiness). NR 24 TC 6 Z9 9 U1 3 U2 10 PU AMER INST AERONAUT ASTRONAUT PI RESTON PA 1801 ALEXANDER BELL DRIVE, STE 500, RESTON, VA 22091-4344 USA SN 0748-4658 J9 J PROPUL POWER JI J. Propul. Power PD SEP-OCT PY 2011 VL 27 IS 5 BP 1064 EP 1078 DI 10.2514/1.B34053 PG 15 WC Engineering, Aerospace SC Engineering GA 831CG UT WOS:000295705700016 ER PT J AU Stamatis, D Dreizin, EL Higa, K AF Stamatis, Demitrios Dreizin, Edward L. Higa, Kelvin TI Thermal Initiation of Al-MoO3 Nanocomposite Materials Prepared by Different Methods SO JOURNAL OF PROPULSION AND POWER LA English DT Article ID ENERGETIC MATERIALS; ALUMINUM; KINETICS; POWDERS; NANO; NANOPARTICLES; OXIDATION; IGNITION; AL AB Two types of nanocomposite reactive materials with the same bulk compositions 8Al center dot MoO3 were prepared and compared with each other. One of the materials was manufactured by arrested reactive milling and the other so-called metastable interstitial composite was manufactured by mixing of nanoscaled individual powders. The materials were characterized using differential scanning calorimetry, thermogravimetric, as well as ignition, experiments using an electrically heated filament and laser as heat sources. The experiments were interpreted using simplified models describing heat transfer in the heated material samples in different experimental configurations. Clear differences in the low-temperature redox reactions, well detectable by differential scanning calorimetry, were established between metastable interstitial composite and arrested-reactive-milling-prepared materials. However, the materials did not differ significantly from each other in the ignition experiments. In the heated filament ignition tests, their ignition temperatures were nearly identical to each other and were in the range of 750-800 K. These ignition temperatures coincided with the temperatures at which main exothermic processes were detected in differential scanning calorimetry experiments. In laser ignition experiments performed with consolidated pellets of both materials, metastable interstitial composite pellets produced consistently stronger pressure pulses. The ignition delays were similar for the pellets of both materials prepared with the same porosity. Analysis of the heat transfer in the pellets heated by the laser suggested that the laser-exposed pellet surfaces were heated to approximately the same temperature before ignition for both materials. This temperature was estimated to be close to 500 K, neglecting the exothermic reactions preceding ignition and possible fragmentation of the heated pellets. Taking into account both phenomena is expected to result in a higher surface temperature, which would better represent the experimental situation. It is proposed that the ignition of both metastable interstitial composite and arrested-reactive-milling-prepared materials at the same temperature can be explained by a thermodynamically driven transformation of a protective amorphous alumina into a crystalline polymorph. C1 [Stamatis, Demitrios; Dreizin, Edward L.] New Jersey Inst Technol, Newark, NJ 07102 USA. [Higa, Kelvin] USN, Air Warfare Ctr, Weap Div, China Lake, CA 93555 USA. RP Stamatis, D (reprint author), Dept Chem Biol & Pharmaceut Engn, University Hts, NJ USA. RI Dreizin, Edward/O-6416-2014; OI Dreizin, Edward/0000-0003-0859-0984 FU Defense Threat Reduction Agency FX This work was supported by the Defense Threat Reduction Agency. NR 22 TC 13 Z9 13 U1 0 U2 13 PU AMER INST AERONAUT ASTRONAUT PI RESTON PA 1801 ALEXANDER BELL DRIVE, STE 500, RESTON, VA 22091-4344 USA SN 0748-4658 J9 J PROPUL POWER JI J. Propul. Power PD SEP-OCT PY 2011 VL 27 IS 5 BP 1079 EP 1087 DI 10.2514/1.B34179 PG 9 WC Engineering, Aerospace SC Engineering GA 831CG UT WOS:000295705700017 ER PT J AU Frantz, JA Bekele, RY Nguyen, VQ Sanghera, JS Bruce, A Frolov, SV Cyrus, M Aggarwal, ID AF Frantz, J. A. Bekele, R. Y. Nguyen, V. Q. Sanghera, J. S. Bruce, A. Frolov, S. V. Cyrus, M. Aggarwal, I. D. TI Cu(In,Ga)Se-2 thin films and devices sputtered from a single target without additional selenization SO THIN SOLID FILMS LA English DT Article DE Cu(In,Ga)Se2; Sputtering; Photovoltaics; Solar cells; Quartenary target; X-ray diffraction; Surface morphology ID SOLAR-CELL AB Typically, Cu(In,Ga)Se-2 (CIGS) thin films for photovoltaic devices are deposited by co-evaporation or, alternately, by deposition of the metals with or followed by treatment in a selenium environment. In this article, we describe CIGS films that are instead deposited by RF magnetron sputtering from a single quaternary target without any additional selenization. Devices built with these films exhibit efficiencies as high as 8.9%. We demonstrate that deposition power can be varied in order to change the film morphology and improve device performance. Published by Elsevier B.V. C1 [Frantz, J. A.; Bekele, R. Y.; Nguyen, V. Q.; Sanghera, J. S.; Aggarwal, I. D.] USN, Res Lab, Washington, DC 20375 USA. [Bruce, A.; Frolov, S. V.; Cyrus, M.] Sunlight Photon, S Plainfield, NJ 07080 USA. RP Frantz, JA (reprint author), USN, Res Lab, Code 5623,4555 Overlook Ave SW, Washington, DC 20375 USA. EM jesse.frantz@nrl.navy.mil NR 12 TC 55 Z9 61 U1 1 U2 46 PU ELSEVIER SCIENCE SA PI LAUSANNE PA PO BOX 564, 1001 LAUSANNE, SWITZERLAND SN 0040-6090 J9 THIN SOLID FILMS JI Thin Solid Films PD SEP 1 PY 2011 VL 519 IS 22 BP 7763 EP 7765 DI 10.1016/j.tsf.2011.06.014 PG 3 WC Materials Science, Multidisciplinary; Materials Science, Coatings & Films; Physics, Applied; Physics, Condensed Matter SC Materials Science; Physics GA 822OC UT WOS:000295057000024 ER PT J AU DeLisa, DF AF DeLisa, Dianne Frye TI Navy Metalworking Center Cuts Costs through Innovative Technology SO ADVANCED MATERIALS & PROCESSES LA English DT Article C1 USN, Metalworking Ctr, Johnstown, PA USA. RP DeLisa, DF (reprint author), USN, Metalworking Ctr, Johnstown, PA USA. FU NMC FX For more information on NMC funding and contract options, contact Dr. Daniel L. Winterscheidt, NMC Program Director (814/269-6840; email: winter@ctc.com). Other points of contact include Rob Akans, NMC Technical Director (703/310-5634; email: akansr@ctc.com), Denise Piastrelli, NMC Business Manager (717/565-4405; email: piastred@ctc.com), and Dianne Frye DeLisa, NMC Communications Specialist (814/248-7608; email: delisad@ctc.com), Navy Metalworking Center, 100 CTC Dr., Johnstown, PA 15904, www.nmc.ctc.com. NR 0 TC 0 Z9 0 U1 0 U2 1 PU ASM INT PI MATERIALS PARK PA SUBSCRIPTIONS SPECIALIST CUSTOMER SERVICE, MATERIALS PARK, OH 44073-0002 USA SN 0882-7958 J9 ADV MATER PROCESS JI Adv. Mater. Process. PD SEP PY 2011 VL 169 IS 9 BP 21 EP 25 PG 5 WC Materials Science, Multidisciplinary SC Materials Science GA 830IX UT WOS:000295651800002 ER PT J AU Copley, S Martukanitz, R Frazier, W Rigdon, M AF Copley, Stephen Martukanitz, Richard Frazier, William Rigdon, Michael TI Mechanical Properties of Parts Formed by Laser Additive Manufacturing SO ADVANCED MATERIALS & PROCESSES LA English DT Article C1 [Copley, Stephen] Penn State Univ, Appl Res Lab, State Coll, PA 16804 USA. [Frazier, William] USN, Air Syst Command, Lusby, MD USA. RP Copley, S (reprint author), Penn State Univ, Appl Res Lab, State Coll, PA 16804 USA. EM smc21@psu.edu NR 0 TC 2 Z9 2 U1 0 U2 3 PU ASM INT PI MATERIALS PARK PA SUBSCRIPTIONS SPECIALIST CUSTOMER SERVICE, MATERIALS PARK, OH 44073-0002 USA SN 0882-7958 J9 ADV MATER PROCESS JI Adv. Mater. Process. PD SEP PY 2011 VL 169 IS 9 BP 26 EP 29 PG 4 WC Materials Science, Multidisciplinary SC Materials Science GA 830IX UT WOS:000295651800003 ER PT J AU Denning, PJ Raj, R AF Denning, Peter J. Raj, Ritu TI The Profession of IT Managing Time, Part 2 SO COMMUNICATIONS OF THE ACM LA English DT Editorial Material C1 [Denning, Peter J.] USN, Postgrad Sch, Cebrowski Inst Informat Innovat, Monterey, CA USA. RP Denning, PJ (reprint author), USN, Postgrad Sch, Cebrowski Inst Informat Innovat, Monterey, CA USA. EM pjd@nps.edu; ritu@orchmail.com NR 4 TC 1 Z9 1 U1 0 U2 1 PU ASSOC COMPUTING MACHINERY PI NEW YORK PA 2 PENN PLAZA, STE 701, NEW YORK, NY 10121-0701 USA SN 0001-0782 J9 COMMUN ACM JI Commun. ACM PD SEP PY 2011 VL 54 IS 9 BP 31 EP 33 DI 10.1145/1995376.1995388 PG 3 WC Computer Science, Hardware & Architecture; Computer Science, Software Engineering; Computer Science, Theory & Methods SC Computer Science GA 831FR UT WOS:000295714600018 ER PT J AU Gangopadhyay, A Lermusiaux, PFJ Rosenfeld, L Robinson, AR Calado, L Kim, HS Leslie, WG Haley, PJ AF Gangopadhyay, Avijit Lermusiaux, Pierre F. J. Rosenfeld, Leslie Robinson, Allan R. Calado, Leandro Kim, Hyun Sook Leslie, Wayne G. Haley, Patrick J., Jr. TI The California Current System: A multiscale overview and the development of a feature-oriented regional modeling system (FORMS) SO DYNAMICS OF ATMOSPHERES AND OCEANS LA English DT Article DE California; Current System; Feature models; FORMS; Upwelling; Data assimilation ID COASTAL TRANSITION ZONE; MULTIVARIATE GEOPHYSICAL FIELDS; WATER MASS CHARACTERISTICS; WESTERN NORTH-ATLANTIC; DATA ASSIMILATION; MONTEREY BAY; SUBMESOSCALE TRANSITION; COLD FILAMENTS; POINT ARENA; PHYTOPLANKTON PIGMENT AB Over the past decade, the feature-oriented regional modeling methodology has been developed and applied in several ocean domains, including the western North Atlantic and tropical North Atlantic. This methodology is model-independent and can be utilized with or without satellite and/or in situ observations. Here we develop new feature-oriented models for the eastern North Pacific from 36 degrees to 48 degrees N - essentially, most of the regional eastern boundary current. This is the first time feature-modeling has been applied to a complex eastern boundary current system. As a prerequisite to feature modeling, prevalent features that comprise the multiscale and complex circulation in the California Current system (CCS) are first overviewed. This description is based on contemporary understanding of the features and their dominant space and time scales of variability. A synergistic configuration of circulation features interacting with one another on multiple and sometimes overlapping space and time scales as a meander-eddy-upwelling system is presented. The second step is to define the feature-oriented regional modeling system (FORMS). The major multiscale circulation features include the mean flow and southeastward meandering jet(s) of the California Current (CC), the poleward flowing California Undercurrent (CUC), and six upwelling regions along the coastline. Next, the typical synoptic width, location, vertical extent, and core characteristics of these features and their dominant scales of variability are identified from past observational, theoretical and modeling studies. The parameterized features are then melded with the climatology, in situ and remotely sensed data, as available. The methodology is exemplified here for initialization of primitive-equation models. Dynamical simulations are run as nowcasts and short-term (4-6 weeks) forecasts using these feature models (FM) as initial fields and the Princeton Ocean Model (POM) for dynamics. The set of simulations over a 40-day period illustrate the applicability of FORMS to a transient eastern boundary current region such as the CCS. Comparisons are made with simulations initialized from climatology only. The FORMS approach increases skill in several factors, including the: (i) maintenance of the low-salinity pool in the core of the CC; (ii) representation of eddy activity inshore of the coastal transition zone; (iii) realistic eddy kinetic energy evolution; (iv) subsurface (intermediate depth) mesoscale feature evolution; and (v) deep poleward flow evolution. (C) 2011 Elsevier B.V. All rights reserved. C1 [Gangopadhyay, Avijit] Univ Massachusetts Dartmouth, Sch Marine Sci & Technol, Fairhaven, MA 02719 USA. [Lermusiaux, Pierre F. J.; Leslie, Wayne G.; Haley, Patrick J., Jr.] MIT, Dept Mech Engn, Cambridge, MA 02139 USA. [Rosenfeld, Leslie] USN, Postgrad Sch, Monterey, CA USA. [Robinson, Allan R.] Harvard Univ, Div Appl Sci, Cambridge, MA 02138 USA. [Calado, Leandro] Marinha Brasil, Inst Estudos Mar Almirante Paulo Moreira IEAPM, BR-28930000 Arraial Do Cabo, RJ, Brazil. [Kim, Hyun Sook] NCEP, Silver Spring, MD USA. RP Gangopadhyay, A (reprint author), Univ Massachusetts Dartmouth, Sch Marine Sci & Technol, Suite 325,200 Mill Rd, Fairhaven, MA 02719 USA. EM Avijit@umassd.edu RI Lermusiaux, Pierre/H-6003-2011 FU Office of Naval Research at the University of Massachusetts at Dartmouth [N00014-03-1-0411, N00014-03-1-0206]; ONR [N00014-03-WR-20009, N00014-08-1-1097, N00014-08-1-0680]; MURI-ASAP FX This work was funded by the Office of Naval Research grants N00014-03-1-0411 and N00014-03-1-0206 at the University of Massachusetts at Dartmouth. Leslie Rosenfeld's participation was supported by ONR grant N00014-03-WR-20009. PFJL, PJH and WGL are grateful to ONR for support under grant N00014-08-1-1097, N00014-08-1-0680 and MURI-ASAP to the Massachusetts Institute of Technology. Our special thanks to Dr. Jim Bellingham and his group at MBARI for numerous informative discussions and for making the data available from the MUSE and AOSN2 experiments. We are grateful to all who contributed to this effort by providing datasets. We especially acknowledge Drs. Ken Brink, Tommy Dickey, Francisco Chavez, Toby Garfield, Alex Warn-Varnas, Shaun Johnston, Curt Collins, Margaret McManus, Libe Washburn, and Erika McPhee-Shaw for their help and support in procuring the datasets from various sources. We also learned from discussions with Steve Ramp, Naomi Leonard, Russ Davis and Dave Fratantoni. We appreciate the editorial assistance provided by Mr. Frank Smith and graphics help of Ms. Carolina Nobre at SMAST. Finally, we are grateful to two anonymous reviewers for their insightful comments and encouragement for an earlier version of this manuscript, which led to substantial improvement of the presentation. We also thank Art Miller for his editing work and comments. This is an AOSN and MBO6 Contribution. This is number 11-0102 in the SMAST Contribution Series, School for Marine Science and Technology, University of Massachusetts Dartmouth. NR 151 TC 7 Z9 8 U1 0 U2 7 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0377-0265 EI 1872-6879 J9 DYNAM ATMOS OCEANS JI Dyn. Atmos. Oceans PD SEP PY 2011 VL 52 IS 1-2 SI SI BP 131 EP 169 DI 10.1016/j.dynatmoce.2011.04.003 PG 39 WC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences; Oceanography SC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences; Oceanography GA 828KD UT WOS:000295499000009 ER PT J AU Ramp, SR Lermusiaux, PFJ Shulman, I Chao, Y Wolf, RE Bahr, FL AF Ramp, Steven R. Lermusiaux, Pierre F. J. Shulman, Igor Chao, Yi Wolf, Rebecca E. Bahr, Frederick L. TI Oceanographic and atmospheric conditions on the continental shelf north of the Monterey Bay during August 2006 SO DYNAMICS OF ATMOSPHERES AND OCEANS LA English DT Article DE Coastal circulation; Air/sea interaction; Upwelling; Ocean modeling and prediction; USA/West Coast/California/Monterey Bay ID OCEAN DYNAMICS EXPERIMENT; CENTRAL CALIFORNIA; SEA-LEVEL; WEST-COAST; MOORED OBSERVATIONS; BOUNDARY-LAYER; UPPER SLOPE; TEMPERATURE; VARIABILITY; CURRENTS AB A comprehensive data set from the ocean and atmosphere was obtained just north of the Monterey Bay as part of the Monterey Bay 2006 (MB06) field experiment. The wind stress, heat fluxes, and sea surface temperature were sampled by the Naval Postgraduate School's TWIN OTTER research aircraft. In situ data were collected using ships, moorings, gliders and AUVs. Four data-assimilating numerical models were additionally run, including the Coupled Ocean/Atmosphere Mesoscale Prediction System (COAMPS(R)) model for the atmosphere and the Harvard Ocean Prediction System (HOPS), the Regional Ocean Modeling System (ROMS), and the Navy Coastal Ocean Model (NCOM) for the ocean. The scientific focus of the Adaptive Sampling and Prediction Experiment (ASAP) was on the upwelling/relaxation cycle and the resulting three-dimensional coastal circulation near a coastal promontory, in this case Point Ano Nuevo, CA. The emphasis of this study is on the circulation over the continental shelf as estimated from the wind forcing, two ADCP moorings, and model outputs. The wind stress during August 2006 consisted of 3-10 day upwelling favorable events separated by brief 1-3 day relaxations. During the first two weeks there was some correlation between local winds and currents and the three models' capability to reproduce the events. During the last two weeks, largely equatorward surface wind stress forced the sea surface and barotropic poleward flow occurred over the shelf, reducing model skill at predicting the circulation. The poleward flow was apparently remotely forced by mesoscale eddies and alongshore pressure gradients, which were not well simulated by the models. The small, high-resolution model domains were highly reliant on correct open boundary conditions to drive these larger-scale poleward flows. Multiply-nested models were no more effective than well-initialized local models in this respect. (C) 2011 Elsevier B.V. All rights reserved. C1 [Ramp, Steven R.] Soliton Ocean Serv Inc, Carmel Valley, CA 93924 USA. [Lermusiaux, Pierre F. J.] MIT, Cambridge, MA 02139 USA. [Shulman, Igor] USN, Res Lab, Stennis Space Ctr, MS 39529 USA. [Chao, Yi] CALTECH, Jet Prop Lab, Pasadena, CA 91109 USA. [Wolf, Rebecca E.] USN, Postgrad Sch, Monterey, CA 93943 USA. [Bahr, Frederick L.] Monterey Bay Aquarium Res Inst, Moss Landing, CA 95039 USA. RP Ramp, SR (reprint author), Soliton Ocean Serv Inc, Carmel Valley, CA 93924 USA. EM sramp@solitonocean.com RI Lermusiaux, Pierre/H-6003-2011 FU National Aeronautics and Space Administration; Office of Naval Research FX Joe Rice (Navel Postgraduate School) arranged and installed the real-time data transmission via the Seaweb network. Marla Stone expertly prepared, deployed, and recovered the moorings. The crew at the NPS Center for Interdisciplinary Remotely-Piloted Aircraft Studies (CIRPAS), under the direction of Bob Bluth and Haf Jonsson, expertly piloted and maintained the TWIN OTrER aircraft. Todd Anderson (NPS) went on every flight to operate the scientific instrumentation package on board. PFJL thanks P.J. Haley and W.G. Leslie for discussions and collaborations. IS thanks S. Anderson and P. Sakalaukus for programming and computer support. This research was carried out in part by the Jet Propulsion Laboratory (JPL), California Institute of Technology, under contract with the National Aeronautics and Space Administration. The authors thank the whole MB06 team for their close collaborations over several years. We thank the Office of Naval Research for support under the MURI-ASAP grants. NR 45 TC 12 Z9 12 U1 0 U2 10 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0377-0265 J9 DYNAM ATMOS OCEANS JI Dyn. Atmos. Oceans PD SEP PY 2011 VL 52 IS 1-2 SI SI BP 192 EP 223 DI 10.1016/j.dynatmoce.2011.04.005 PG 32 WC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences; Oceanography SC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences; Oceanography GA 828KD UT WOS:000295499000011 ER PT J AU Vurgaftman, I Bewley, WW Canedy, CL Kim, CS Kim, M Lindle, JR Merritt, CD Abell, J Meyer, JR AF Vurgaftman, Igor Bewley, William W. Canedy, Chadwick L. Kim, Chul Soo Kim, Mijin Lindle, J. Ryan Merritt, Charles D. Abell, Joshua Meyer, Jerry R. TI Mid-IR Type-II Interband Cascade Lasers SO IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS LA English DT Article DE GaSb; interband cascade lasers (ICLs); midinfrared; semiconductor lasers ID MU-M; QUANTUM-WELLS; PERFORMANCE; TEMPERATURE; SEMICONDUCTORS; RECOMBINATION; SUPERLATTICES; WAVELENGTHS; ABSORPTION; THRESHOLD AB The interband cascade laser (ICL) concept provides robust and efficient emission in the midwave infrared spectral band. While the geometry is somewhat analogous to that of a quantum cascade laser employing intersubband transitions, the ICL implementation exploits the type-II band alignment of the GaSb-based material system. A semimetallic band overlap at the boundary between the electron and hole injector regions automatically generates carriers with densities tunable by quantum confinement. Electrical injection then replenishes the carriers already present rather than creating the population inversion. In this paper, we describe and analyze the physical principles governing ICL operation, and discuss specific modifications to the active region, electron injector, hole injector, and waveguide designs that demonstrably improve the performance. The pulsed I-V and L-I characteristics of devices processed from over 50 wafers provide a statistically meaningful confirmation of the established trends. C1 [Vurgaftman, Igor; Bewley, William W.; Canedy, Chadwick L.; Kim, Chul Soo; Kim, Mijin; Lindle, J. Ryan; Merritt, Charles D.; Abell, Joshua; Meyer, Jerry R.] USN, Res Lab, Washington, DC 20375 USA. RP Vurgaftman, I (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM vurgaftman@nrl.navy.mil; william.bewley@nrl.navy.mil; chadwick.canedy@nrl.navy.mil; chulsoo.kim@nrl.navy.mil; mijin.kim.ctr@nrl.navy.mil; ryan.lindle@nrl.navy.mil; charles.merritt@nrl.navy.mil; joshua.abell@nrl.navy.mil; jerry.meyer@nrl.navy.mil FU Office of Naval Research FX This work was supported by the Office of Naval Research. NR 55 TC 60 Z9 61 U1 6 U2 40 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1077-260X J9 IEEE J SEL TOP QUANT JI IEEE J. Sel. Top. Quantum Electron. PD SEP-OCT PY 2011 VL 17 IS 5 BP 1435 EP 1444 DI 10.1109/JSTQE.2011.2114331 PG 10 WC Engineering, Electrical & Electronic; Optics; Physics, Applied SC Engineering; Optics; Physics GA 829MK UT WOS:000295586100038 ER PT J AU Santos, ED Alves, N Dias, GM Mazotto, AM Vermelho, A Vora, GJ Wilson, B Beltran, VH Bourne, DG Le Roux, F Thompson, FL AF Santos, Eidy de O. Alves, Nelson, Jr. Dias, Graciela M. Mazotto, Ana Maria Vermelho, Alane Vora, Gary J. Wilson, Bryan Beltran, Victor H. Bourne, David G. Le Roux, Frederique Thompson, Fabiano L. TI Genomic and proteomic analyses of the coral pathogen Vibrio coralliilyticus reveal a diverse virulence repertoire SO ISME JOURNAL LA English DT Article DE V. coralliilyticus; coral disease; zinc-metalloprotease; genome; secretome ID TROUT ONCORHYNCHUS-MYKISS; POCILLOPORA-DAMICORNIS; EXTRACELLULAR METALLOPROTEASE; SYMBIODINIUM STRAINS; PROTEASE; GENE; ANGUILLARUM; VULNIFICUS; CHOLERAE; BACTERIA AB Vibrio coralliilyticus has been implicated as an important pathogen of coral species worldwide. In this study, the nearly complete genome of Vibrio coralliilyticus strain P1 (LMG23696) was sequenced and proteases implicated in virulence of the strain were specifically investigated. The genome sequence of P1 (5 513 256 bp in size) consisted of 5222 coding sequences and 58 RNA genes (53 tRNAs and at least 5 rRNAs). Seventeen metalloprotease and effector (vgrG, hlyA and hcp) genes were identified in the genome and expressed proteases were also detected in the secretome of P1. As the VcpA zinc-metalloprotease has been considered an important virulence factor of V. coralliilyticus, a vcpA deletion mutant was constructed to evaluate the effect of this gene in animal pathogenesis. Both wild-type and mutant (Delta vcpA) strains exhibited similar virulence characteristics that resulted in high mortality in Artemia and Drosophila pathogenicity bioassays and strong photosystem II inactivation of the coral dinoflagellate endosymbiont (Symbiodinium). In contrast, the DvcpA mutant demonstrated higher hemolytic activity and secreted 18 proteins not secreted by the wild type. These proteins included four types of metalloproteases, a chitinase, a hemolysin-related protein RbmC, the Hcp protein and 12 hypothetical proteins. Overall, the results of this study indicate that V. coralliilyticus strain P1 has a diverse virulence repertoire that possibly enables this bacterium to be an efficient animal pathogen. The ISME Journal (2011) 5, 1471-1483; doi:10.1038/ismej.2011.19; published online 31 March 2011 C1 [Santos, Eidy de O.; Alves, Nelson, Jr.; Dias, Graciela M.; Thompson, Fabiano L.] UFRJ, Inst Biol, Microbiol Lab, BR-21944970 Rio De Janeiro, Brazil. [Mazotto, Ana Maria; Vermelho, Alane] UFRJ, Lab Proteases, Inst Microbiol, BR-21944970 Rio De Janeiro, Brazil. [Vora, Gary J.] USN, Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. [Wilson, Bryan; Beltran, Victor H.; Bourne, David G.] Australian Inst Marine Sci, Ctr Marine Microbiol & Genet, Townsville, Qld, Australia. [Le Roux, Frederique] IFREMER, Lab Physiol Invertebres, Brest, France. [Le Roux, Frederique] FR2424 CNRS UPMC Stn Biol Roscoff, Paris, France. RP Thompson, FL (reprint author), UFRJ, Inst Biol, Microbiol Lab, BR-21944970 Rio De Janeiro, Brazil. EM fabiano.thompson@biologia.ufrj.br RI Bourne, David/B-5073-2008; OI Bourne, David/0000-0002-1492-8710; Vora, Gary/0000-0002-0657-8597 FU National Council of Technological and Scientific Development, Brazil (CNPq); Smart state postdoctoral fellowship; CNPq FX We would like to thank the Luz Sincroton National Laboratory for the use of the nano-LC-MS/MS mass spectrometer and Proteomic Network of Rio de Janeiro for equipment and reagent lending. We thank Gabrielle V Souza for her excellent technical assistance. This study was partially funded by grants from the National Council of Technological and Scientific Development, Brazil (CNPq). BW thanks a Smart state postdoctoral fellowship. FLT and EOS have CNPq fellowships. NR 52 TC 21 Z9 21 U1 1 U2 31 PU NATURE PUBLISHING GROUP PI NEW YORK PA 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA SN 1751-7362 J9 ISME J JI ISME J. PD SEP PY 2011 VL 5 IS 9 BP 1471 EP 1483 DI 10.1038/ismej.2011.19 PG 13 WC Ecology; Microbiology SC Environmental Sciences & Ecology; Microbiology GA 832DU UT WOS:000295782900008 ER PT J AU DeLand, MT Shettle, EP Thomas, GE Olivero, JJ AF DeLand, Matthew T. Shettle, Eric P. Thomas, Gary E. Olivero, John J. TI Direct observations of PMC local time variations by Aura OMI SO JOURNAL OF ATMOSPHERIC AND SOLAR-TERRESTRIAL PHYSICS LA English DT Article; Proceedings Paper CT 9th International Workshop on Layered Phenomena in the Mesopause Region (LPMR) CY JUL 14, 2009 CL Stockholm Univ, Dept Meteorol, Stockholm, SWEDEN SP Int Commission Middle Atmosphere (ICMA), Int Meteorol Inst, Swedish Natl Space Board, Esrange Space Ctr HO Stockholm Univ, Dept Meteorol DE Polar mesospheric clouds; PMC; Noctilucent clouds; OMI ID POLAR MESOSPHERIC CLOUDS; NOCTILUCENT CLOUDS; DIURNAL-VARIATIONS; NLC OBSERVATIONS; LIDAR; ICE; ODIN/OSIRIS; INSTRUMENT; ALOMAR AB The Ozone Monitoring Instrument (OMI) on the Aura satellite obtains unique measurements for polar mesospheric cloud (PMC) analysis. Its wide cross-track viewing swath and high along-track spatial resolution makes it possible to directly evaluate PMC occurrence frequency and brightness variations between 65 and 85 latitude as a function of local time over a 12-14 h continuous period. OMI PMC local time variations are closely coupled to concurrent variations in measurement scattering angle, so that ice phase function effects must be considered when interpreting the observations. Two different phase functions corresponding to bright and faint clouds are examined in this analysis. OMI observations show maximum frequency and albedo values at 8-10 h local time in the Northern Hemisphere, with decreasing amplitude at higher latitudes. Southern Hemisphere values reach a minimum at 18-20 h LT. Larger variations are seen in Northern Hemisphere data. No statistically significant longitudinal dependence was seen. (C) 2010 Elsevier Ltd. All rights reserved. C1 [DeLand, Matthew T.] Sci Syst & Applicat Inc SSAI, Lanham, MD 20706 USA. [Shettle, Eric P.] USN, Res Lab, Remote Sensing Div, Washington, DC 20375 USA. [Thomas, Gary E.] Univ Colorado, LASP, Boulder, CO 80309 USA. [Olivero, John J.] Embry Riddle Aeronaut Univ, Dept Phys Sci, Daytona Beach, FL 32114 USA. RP DeLand, MT (reprint author), Sci Syst & Applicat Inc SSAI, 10210 Greenbelt Rd,Suite 600, Lanham, MD 20706 USA. EM matthew.deland@ssaihq.com NR 27 TC 5 Z9 5 U1 0 U2 1 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 1364-6826 EI 1879-1824 J9 J ATMOS SOL-TERR PHY JI J. Atmos. Sol.-Terr. Phys. PD SEP PY 2011 VL 73 IS 14-15 SI SI BP 2049 EP 2064 DI 10.1016/j.jastp.2010.11.019 PG 16 WC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences SC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences GA 829BT UT WOS:000295551000002 ER PT J AU Pautet, PD Stegman, J Wrasse, CM Nielsen, K Takahashi, H Taylor, MJ Hoppel, KW Eckermann, SD AF Pautet, P. -D. Stegman, J. Wrasse, C. M. Nielsen, K. Takahashi, H. Taylor, M. J. Hoppel, K. W. Eckermann, S. D. TI Analysis of gravity waves structures visible in noctilucent cloud images SO JOURNAL OF ATMOSPHERIC AND SOLAR-TERRESTRIAL PHYSICS LA English DT Article; Proceedings Paper CT 9th International Workshop on Layered Phenomena in the Mesopause Region (LPMR) CY JUL 14, 2009 CL Stockholm Univ, Dept Meteorol, Stockholm, SWEDEN SP Int Commission Middle Atmosphere (ICMA), Int Meteorol Inst, Swedish Natl Space Board, Esrange Space Ctr HO Stockholm Univ, Dept Meteorol DE Noctilucent clouds (NLC); Mesosphere lower thermosphere (MLT); Gravity waves; Image processing ID MIDDLE ATMOSPHERE; TEMPERATURE-VARIATIONS; LATITUDES; OH; PROPAGATION; EQUATORIAL; MESOPAUSE; BREAKING; HEIGHT; REGION AB The noctilucent clouds (NLC) are high-altitude bright cloud formations visible under certain conditions from high-latitude places during the summer months. Even if the exact nature of these clouds still remains a mystery, they are an efficient tracer of the dynamic processes at their level, particularly the gravity waves propagating from the stratosphere through the mesopause layer. In this paper, we describe a technique developed to analyze the structures visible in the NLC images taken every summer night since 2004 from Stockholm, Sweden (59.4 degrees N). The parameters of 30 short-period gravity wave events have been measured and compared with older datasets obtained mostly from low and mid-latitude sites, using airglow imaging techniques. The horizontal wavelengths are in good agreement with previous results while the observed horizontal phase speeds exhibit smaller values than for other sites. The directionality of the waves presents strong poleward preference, traditionally observed during the summer season. This anisotropy and the difference in the phase speed distribution cannot be explained by the filtering due to the background wind field but more probably by the position of the gravity waves sources, located to the south of the observation site. (C) 2010 Elsevier Ltd. All rights reserved. C1 [Pautet, P. -D.; Taylor, M. J.] Utah State Univ, Ctr Atmospher & Space Sci, Logan, UT 84322 USA. [Stegman, J.] Stockholm Univ, Dept Meteorol, S-10691 Stockholm, Sweden. [Wrasse, C. M.] Univ Vale do Paraiba, Inst Pesquisa & Desenvolvimento, Sao Jose Dos Campos, SP, Brazil. [Nielsen, K.] Computat Phys Inc, Boulder, CO USA. [Takahashi, H.] Inst Nacionais Pesquisas Espaciais, Sao Jose Dos Campos, SP, Brazil. [Hoppel, K. W.; Eckermann, S. D.] USN, Res Lab, Washington, DC 20375 USA. RP Pautet, PD (reprint author), Utah State Univ, Ctr Atmospher & Space Sci, Logan, UT 84322 USA. EM dominiquepautet@gmail.com RI Wrasse, Cristiano/N-6556-2013 NR 50 TC 18 Z9 19 U1 1 U2 5 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 1364-6826 EI 1879-1824 J9 J ATMOS SOL-TERR PHY JI J. Atmos. Sol.-Terr. Phys. PD SEP PY 2011 VL 73 IS 14-15 SI SI BP 2082 EP 2090 DI 10.1016/j.jastp.2010.06.001 PG 9 WC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences SC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences GA 829BT UT WOS:000295551000005 ER PT J AU Gallagher, EL MacMahan, J Reniers, AJHM Brown, J Thornton, EB AF Gallagher, Edith L. MacMahan, Jamie Reniers, A. J. H. M. Brown, Jenna Thornton, Edward B. TI Grain size variability on a rip-channeled beach SO MARINE GEOLOGY LA English DT Article DE grain size; beaches; digital imaging; nearshore ID CONTINENTAL-SHELF; BOTTOM FRICTION; DIGITAL IMAGES; SEDIMENT; EVOLUTION; HOTSPOTS; COAST AB Grain size is an important variable when predicting beach morphodynamics. Beaches, to the eye, seem relatively uniform in grain size and morphodynamic modeling efforts usually assume a single mean grain size for an entire beach environment. Therefore, estimating grain size is traditionally done by collecting only a few samples and averaging to characterize the mean grain size of the whole beach. However, some studies have shown that even small variations in grain size can have a significant effect on model results when predicting beach morphology changes. Here, a mobile digital imaging system (DIS) has been developed for surveying spatial and temporal variation in grain size across a beach following the ideas of Rubin (2004). Using an off-the-shelf camera and underwater housing, macro photographs are taken of sand across a beach, which produce estimates of mean grain size that are highly correlated with estimates from sieves (R(2)= 0.92). High resolution maps of mean surface grain size are produced using the DIS (with similar to 1000 images over a 300 x 500 m area), which suggest that large variations in grain size exist (0.2-0.7 mm over tens of meters with accuracies of similar to +/- 0.03 mm) and that there is a correlation between spatial grain size variations and morphological variability. (C) 2011 Elsevier B.V. All rights reserved. C1 [Gallagher, Edith L.] Franklin & Marshall Coll, Lancaster, PA 17604 USA. [MacMahan, Jamie; Brown, Jenna; Thornton, Edward B.] USN, Dept Oceanog, Postgrad Sch, Monterey, CA 93943 USA. [Reniers, A. J. H. M.] Univ Miami, Rosenstiel Sch Marine Sci, Key Biscayne, FL 33149 USA. RP Gallagher, EL (reprint author), Franklin & Marshall Coll, POB 3003, Lancaster, PA 17604 USA. EM edith.gallagher@fandm.edu FU Deltares Coastal Care (Kustlijnzorg); Office of Naval Research Coastal Geosciences [N000140510153]; National Science Foundation [OCE0340758, EAR0952164, EAR0952225, OCE0754426] FX This work was funded by Deltares Coastal Care (Kustlijnzorg), the Office of Naval Research Coastal Geosciences grant N000140510153 and the National Science Foundation grant numbers OCE0340758 and EAR0952164. Funding for AR was provided by National Science Foundation EAR0952225 and OCE0754426. JM was funded by Office of Naval Research Coastal Geosciences and the National Science Foundation. The video images were made possible by NIWA (New Zealand) and SHOM-DGA (France) with the data processing having been done by Rafael Almar and Vincent Marieu. Early parts of the DIS development were supported (including travel funds and logistics) by Paul Russell and Gerd Masselink (University of Plymouth). Friends and colleagues who also helped enormously include Jeff Brown, Clement Gandon, Martijn Henriquez, Matthieu de Schipper, Marije Smit, Nadia Senechal, Ian Smithgall, Jurre de Vries and Sierd de Vries. NR 24 TC 11 Z9 11 U1 0 U2 10 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0025-3227 J9 MAR GEOL JI Mar. Geol. PD SEP 1 PY 2011 VL 287 IS 1-4 BP 43 EP 53 DI 10.1016/j.margeo.2011.06.010 PG 11 WC Geosciences, Multidisciplinary; Oceanography SC Geology; Oceanography GA 828ZW UT WOS:000295545100004 ER PT J AU Lin, KY Wei, YF AF Lin, Kyle Y. Wei, Yu-Feng TI Optimal probing control for wireless transmission when the payload is negligible SO OPTIMAL CONTROL APPLICATIONS & METHODS LA English DT Article DE probing control; dynamic programming; optimal stopping; energy management AB A mobile electronic device needs to periodically connect to a stationary receiver, but the information to transfer is minimal. One such example is the electronic bracelet used in house arrest, where the main purpose is to inform the receiver that the person is in the house. Because the mobile device does not know its current distance from the receiver, it has incentive to first send a low-strength signal to conserve its battery energy. If the low-strength signal fails to reach the receiver, the mobile device then gradually increases its signal strength until a successful connection occurs. By formulating the problem as a dynamic program, we characterize the structure of the optimal probing policy and develop an algorithm to compute it. We also consider a discrete approximation that can be easily implemented in practice. Numerical examples show promising improvement of the derived policy over naive heuristic policies, and that the derived policy is robust when there are small errors in estimating the distribution of the distance between the mobile device and the receiver. Copyright (C) 2010 John Wiley & Sons, Ltd. C1 [Lin, Kyle Y.] USN, Postgrad Sch, Dept Operat Res, Monterey, CA 93943 USA. [Wei, Yu-Feng] Trinity Partners, Waltham, MA 02451 USA. RP Lin, KY (reprint author), USN, Postgrad Sch, Dept Operat Res, 1411 Cunningham Rd, Monterey, CA 93943 USA. EM kylin@nps.edu OI Lin, Kyle/0000-0002-3769-1891 FU Naval Postgraduate School FX This material is based upon work supported by the Research Initiation Program at the Naval Postgraduate School. The authors thank two anonymous reviewers for their helpful comments. NR 13 TC 0 Z9 0 U1 0 U2 1 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 0143-2087 J9 OPTIM CONTR APPL MET JI Optim. Control Appl. Methods PD SEP-OCT PY 2011 VL 32 IS 5 BP 558 EP 573 DI 10.1002/oca.954 PG 16 WC Automation & Control Systems; Operations Research & Management Science; Mathematics, Applied SC Automation & Control Systems; Operations Research & Management Science; Mathematics GA 826PQ UT WOS:000295366500004 ER PT J AU Abramowski, A Acero, F Aharonian, F Akhperjanian, AG Anton, G Barnacka, A de Almeida, UB Bazer-Bachi, AR Becherini, Y Becker, J Behera, B Bernlohr, K Bochow, A Boisson, C Bolmont, J Bordas, P Borrel, V Brucker, J Brun, F Brun, P Bulik, T Busching, I Casanova, S Cerruti, M Chadwick, PM Charbonnier, A Chaves, RCG Cheesebrough, A Chounet, LM Clapson, AC Coignet, G Conrad, J Dalton, M Daniel, MK Davids, ID Degrange, B Deil, C Dickinson, HJ Djannati-Atai, A Domainko, W Drury, LO Dubois, F Dubus, G Dyks, J Dyrda, M Egberts, K Eger, P Espigat, P Fallon, L Farnier, C Fegan, S Feinstein, F Fernandes, MV Fiasson, A Fontaine, G Forster, A Fussling, M Gabici, S Gallant, YA Gast, H Gerard, L Gerbig, D Giebels, B Glicenstein, JF Gluck, B Goret, P Goring, D Hague, JD Hampf, D Hauser, M Heinz, S Heinzelmann, G Henri, G Hermann, G Hinton, JA Hoffmann, A Hofmann, W Hofverberg, P Horns, D Jacholkowska, A de Jager, OC Jahn, C Jamrozy, M Jung, I Kastendieck, MA Katarzynski, K Katz, U Kaufmann, S Keogh, D Kerschhaggl, M Khangulyan, D Khelifi, B Klochkov, D Kluzniak, W Kneiske, T Komin, N Kosack, K Kossakowski, R Laffon, H Lamanna, G Lenain, JP Lennarz, D Lohse, T Lopatin, A Lu, CC Marandon, V Marcowith, A Masbou, J Maurin, D Maxted, N McComb, TJL Medina, MC Mehault, J Nguyen, N Moderski, R Moulin, E Naumann-Godo, M de Naurois, M Nedbal, D Nekrassov, D Nicholas, B Niemiec, J Nolan, SJ Ohm, S Olive, JF Wilhelmi, ED Opitz, B Ostrowski, M Panter, M Arribas, MP Pedaletti, G Pelletier, G Petrucci, PO Pita, S Puhlhofer, G Punch, M Quirrenbach, A Raue, M Rayner, SM Reimer, A Reimer, O Renaud, M de los Reyes, R Rieger, F Ripken, J Rob, L Rosier-Lees, S Rowell, G Rudak, B Rulten, CB Ruppel, J Ryde, F Sahakian, V Santangelo, A Schlickeiser, R Schock, FM Schonwald, A Schwanke, U Schwarzburg, S Schwemmer, S Shalchi, A Sikora, M Skilton, JL Sol, H Spengler, G Stawarz, L Steenkamp, R Stegmann, C Stinzing, F Sushch, I Szostek, A Tam, PH Tavernet, JP Terrier, R Tibolla, O Tluczykont, M Valerius, K van Eldik, C Vasileiadis, G Venter, C Vialle, JP Viana, A Vincent, P Vivier, M Volk, HJ Volpe, F Vorobiov, S Vorster, M Wagner, SJ Ward, M Wierzcholska, A Zajczyk, A Zdziarski, AA Zech, A Zechlin, HS Abdo, AA Ackermann, M Ajello, M Baldini, L Ballet, J Barbiellini, G Bastieri, D Bechtol, K Bellazzini, R Berenji, B Blandford, RD Bonamente, E Borgland, AW Bregeon, J Brez, A Brigida, M Bruel, P Buehler, R Buson, S Caliandro, GA Cameron, RA Cannon, A Caraveo, PA Carrigan, S Casandjian, JM Cavazzuti, E Cecchi, C Celik, O Chekhtman, A Cheung, CC Chiang, J Ciprini, S Claus, R Cohen-Tanugi, J Cutini, S Dermer, CD de Palma, F Silva, EDE Drell, PS Dubois, R Dumora, D Escande, L Favuzzi, C Ferrara, EC Focke, WB Fortin, P Frailis, M Fukazawa, Y Fusco, P Gargano, F Gasparrini, D Gehrels, N Germani, S Giglietto, N Giommi, P Giordano, F Giroletti, M Glanzman, T Godfrey, G Grenier, IA Grove, JE Guiriec, S Hadasch, D Hays, E Horan, D Hughes, RE Johannesson, G Johnson, AS Johnson, WN Kamae, T Katagiri, H Kataoka, J Knodlseder, J Kuss, M Lande, J Latronico, L Lee, SH Longo, F Loparco, F Lott, B Lovellette, MN Lubrano, P Madejski, GM Makeev, A Mazziotta, MN McConville, W McEnery, JE Michelson, PF Mizuno, T Monte, C Monzani, ME Morselli, A Moskalenko, IV Murgia, S Nakamori, T Nishino, S Nolan, PL Norris, JP Nuss, E Ohsugi, T Okumura, A Omodei, N Orlando, E Ormes, JF Ozaki, M Paneque, D Panetta, JH Parent, D Pelassa, V Pepe, M Pesce-Rollins, M Piron, F Porter, TA Raino, S Rando, R Razzano, M Sadrozinski, HFW Sanchez, D Sander, A Sgro, C Siskind, EJ Smith, PD Spandre, G Spinelli, P Strickman, MS Suson, DJ Takahashi, H Takahashi, T Tanaka, T Thayer, JB Thayer, JG Thompson, DJ Tibaldo, L Torres, DF Tosti, G Tramacere, A Troja, E Uehara, T Usher, TL Vandenbroucke, J Vianello, G Vilchez, N Vitale, V Waite, AP Wang, P Winer, BL Wood, KS Yang, Z Ylinen, T Ziegler, M AF Abramowski, A. Acero, F. Aharonian, F. Akhperjanian, A. G. Anton, G. Barnacka, A. de Almeida, U. Barres Bazer-Bachi, A. R. Becherini, Y. Becker, J. Behera, B. Bernloehr, K. Bochow, A. Boisson, C. Bolmont, J. Bordas, P. Borrel, V. Brucker, J. Brun, F. Brun, P. Bulik, T. Buesching, I. Casanova, S. Cerruti, M. Chadwick, P. M. Charbonnier, A. Chaves, R. C. G. Cheesebrough, A. Chounet, L-M Clapson, A. C. Coignet, G. Conrad, J. Dalton, M. Daniel, M. K. Davids, I. D. Degrange, B. Deil, C. Dickinson, H. J. Djannati-Atai, A. Domainko, W. Drury, L. O'C Dubois, F. Dubus, G. Dyks, J. Dyrda, M. Egberts, K. Eger, P. Espigat, P. Fallon, L. Farnier, C. Fegan, S. Feinstein, F. Fernandes, M. V. Fiasson, A. Fontaine, G. Foerster, A. Fuessling, M. Gabici, S. Gallant, Y. A. Gast, H. Gerard, L. Gerbig, D. Giebels, B. Glicenstein, J. F. Glueck, B. Goret, P. Goering, D. Hague, J. D. Hampf, D. Hauser, M. Heinz, S. Heinzelmann, G. Henri, G. Hermann, G. Hinton, J. A. Hoffmann, A. Hofmann, W. Hofverberg, P. Horns, D. Jacholkowska, A. de Jager, O. C. Jahn, C. Jamrozy, M. Jung, I. Kastendieck, M. A. Katarzynski, K. Katz, U. Kaufmann, S. Keogh, D. Kerschhaggl, M. Khangulyan, D. Khelifi, B. Klochkov, D. Kluzniak, W. Kneiske, T. Komin, Nu Kosack, K. Kossakowski, R. Laffon, H. Lamanna, G. Lenain, J-P Lennarz, D. Lohse, T. Lopatin, A. Lu, C-C Marandon, V. Marcowith, A. Masbou, J. Maurin, D. Maxted, N. McComb, T. J. L. Medina, M. C. Mehault, J. Nguyen, N. Moderski, R. Moulin, E. Naumann-Godo, M. de Naurois, M. Nedbal, D. Nekrassov, D. Nicholas, B. Niemiec, J. Nolan, S. J. Ohm, S. Olive, J-F Wilhelmi, E. de Ona Opitz, B. Ostrowski, M. Panter, M. Arribas, M. Paz Pedaletti, G. Pelletier, G. Petrucci, P-O Pita, S. Puehlhofer, G. Punch, M. Quirrenbach, A. Raue, M. Rayner, S. M. Reimer, A. Reimer, O. Renaud, M. de los Reyes, R. Rieger, F. Ripken, J. Rob, L. Rosier-Lees, S. Rowell, G. Rudak, B. Rulten, C. B. Ruppel, J. Ryde, F. Sahakian, V. Santangelo, A. Schlickeiser, R. Schoeck, F. M. Schoenwald, A. Schwanke, U. Schwarzburg, S. Schwemmer, S. Shalchi, A. Sikora, M. Skilton, J. L. Sol, H. Spengler, G. Stawarz, L. Steenkamp, R. Stegmann, C. Stinzing, F. Sushch, I. Szostek, A. Tam, P. H. Tavernet, J-P Terrier, R. Tibolla, O. Tluczykont, M. Valerius, K. van Eldik, C. Vasileiadis, G. Venter, C. Vialle, J. P. Viana, A. Vincent, P. Vivier, M. Voelk, H. J. Volpe, F. Vorobiov, S. Vorster, M. Wagner, S. J. Ward, M. Wierzcholska, A. Zajczyk, A. Zdziarski, A. A. Zech, A. Zechlin, H-S Abdo, A. A. Ackermann, M. Ajello, M. Baldini, L. Ballet, J. Barbiellini, G. Bastieri, D. Bechtol, K. Bellazzini, R. Berenji, B. Blandford, R. D. Bonamente, E. Borgland, A. W. Bregeon, J. Brez, A. Brigida, M. Bruel, P. Buehler, R. Buson, S. Caliandro, G. A. Cameron, R. A. Cannon, A. Caraveo, P. A. Carrigan, S. Casandjian, J. M. Cavazzuti, E. Cecchi, C. Celik, Oe Chekhtman, A. Cheung, C. C. Chiang, J. Ciprini, S. Claus, R. Cohen-Tanugi, J. Cutini, S. Dermer, C. D. de Palma, F. do Couto e Silva, E. Drell, P. S. Dubois, R. Dumora, D. Escande, L. Favuzzi, C. Ferrara, E. C. Focke, W. B. Fortin, P. Frailis, M. Fukazawa, Y. Fusco, P. Gargano, F. Gasparrini, D. Gehrels, N. Germani, S. Giglietto, N. Giommi, P. Giordano, F. Giroletti, M. Glanzman, T. Godfrey, G. Grenier, I. A. Grove, J. E. Guiriec, S. Hadasch, D. Hays, E. Horan, D. Hughes, R. E. Johannesson, G. Johnson, A. S. Johnson, W. N. Kamae, T. Katagiri, H. Kataoka, J. Knoedlseder, J. Kuss, M. Lande, J. Latronico, L. Lee, S-H Longo, F. Loparco, F. Lott, B. Lovellette, M. N. Lubrano, P. Madejski, G. M. Makeev, A. Mazziotta, M. N. McConville, W. McEnery, J. E. Michelson, P. F. Mizuno, T. Monte, C. Monzani, M. E. Morselli, A. Moskalenko, I. V. Murgia, S. Nakamori, T. Nishino, S. Nolan, P. L. Norris, J. P. Nuss, E. Ohsugi, T. Okumura, A. Omodei, N. Orlando, E. Ormes, J. F. Ozaki, M. Paneque, D. Panetta, J. H. Parent, D. Pelassa, V. Pepe, M. Pesce-Rollins, M. Piron, F. Porter, T. A. Raino, S. Rando, R. Razzano, M. Sadrozinski, H. F-W Sanchez, D. Sander, A. Sgro, C. Siskind, E. J. Smith, P. D. Spandre, G. Spinelli, P. Strickman, M. S. Suson, D. J. Takahashi, H. Takahashi, T. Tanaka, T. Thayer, J. B. Thayer, J. G. Thompson, D. J. Tibaldo, L. Torres, D. F. Tosti, G. Tramacere, A. Troja, E. Uehara, T. Usher, T. L. Vandenbroucke, J. Vianello, G. Vilchez, N. Vitale, V. Waite, A. P. Wang, P. Winer, B. L. Wood, K. S. Yang, Z. Ylinen, T. Ziegler, M. CA HESS Collaboration Fermi LAT Collaboration TI Simultaneous multi-wavelength campaign on PKS 2005-489 in a high state SO ASTRONOMY & ASTROPHYSICS LA English DT Article DE galaxies: active; BL Lacertae objects: individual: PKS 2005-489 ID LARGE-AREA TELESCOPE; INFRARED OBSERVATIONS; BACKGROUND-RADIATION; HOST GALAXIES; GAMMA-RAYS; EGRET DATA; BLAZAR; SWIFT; FLARE; PKS-2005-489 AB The high-frequency peaked BL Lac object PKS 2005-489 was the target of a multi-wavelength campaign with simultaneous observations in the TeV gamma-ray (H.E.S.S.), GeV gamma-ray (Fermi/LAT), X-ray (RXTE, Swift), UV (Swift) and optical (ATOM, Swift) bands. This campaign was carried out during a high flux state in the synchrotron regime. The flux in the optical and X-ray bands reached the level of the historical maxima. The hard GeV spectrum observed with Fermi/LAT connects well to the very high energy (VHE, E > 100 GeV) spectrum measured with H.E.S.S. with a peak energy between similar to 5 and 500 GeV. Compared to observations with contemporaneous coverage in the VHE and X-ray bands in 2004, the X-ray flux was similar to 50 times higher during the 2009 campaign while the TeV gamma-ray flux shows marginal variation over the years. The spectral energy distribution during this multi-wavelength campaign was fit by a one zone synchrotron self-Compton model with a well determined cutoff in X-rays. The parameters of a one zone SSC model are inconsistent with variability time scales. The variability behaviour over years with the large changes in synchrotron emission and small changes in the inverse Compton emission does not warrant an interpretation within a one-zone SSC model despite an apparently satisfying fit to the broadband data in 2009. C1 [Abramowski, A.; Fernandes, M. V.; Hampf, D.; Heinzelmann, G.; Horns, D.; Kastendieck, M. A.; Kneiske, T.; Nguyen, N.; Opitz, B.; Raue, M.; Tluczykont, M.; Zechlin, H-S] Univ Hamburg, Inst Expt Phys, D-22761 Hamburg, Germany. 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EM S.Kaufmann@lsw.uni-heidelberg.de; fortin@llr.in2p3.fr; wmcconvi@umd.edu RI Katz, Uli/E-1925-2013; Morselli, Aldo/G-6769-2011; Thompson, David/D-2939-2012; Gehrels, Neil/D-2971-2012; McEnery, Julie/D-6612-2012; Baldini, Luca/E-5396-2012; lubrano, pasquale/F-7269-2012; Kuss, Michael/H-8959-2012; giglietto, nicola/I-8951-2012; Reimer, Olaf/A-3117-2013; van Eldik, Christopher/C-3901-2013; Tosti, Gino/E-9976-2013; Ozaki, Masanobu/K-1165-2013; Tjus, Julia/G-8145-2012; Rando, Riccardo/M-7179-2013; Fontaine, Gerard/D-6420-2014; Hays, Elizabeth/D-3257-2012; Johnson, Neil/G-3309-2014; Venter, Christo/E-6884-2011; Katarzynski, Krzysztof/G-4528-2014; Jamrozy, Marek/F-4507-2015; Casanova, Sabrina/J-8935-2013; Anton, Gisela/C-4840-2013; Johannesson, Gudlaugur/O-8741-2015; Loparco, Francesco/O-8847-2015; Gargano, Fabio/O-8934-2015; Moskalenko, Igor/A-1301-2007; Wang, Pengfei/M-8060-2013; Mazziotta, Mario /O-8867-2015; Sgro, Carmelo/K-3395-2016; Torres, Diego/O-9422-2016; Orlando, E/R-5594-2016; Drury, Luke/B-1916-2017; Moulin, Emmanuel/B-5959-2017; Daniel, Michael/A-2903-2010; Komin, Nukri/J-6781-2015; OI Katz, Uli/0000-0002-7063-4418; Morselli, Aldo/0000-0002-7704-9553; Thompson, David/0000-0001-5217-9135; lubrano, pasquale/0000-0003-0221-4806; giglietto, nicola/0000-0002-9021-2888; Reimer, Olaf/0000-0001-6953-1385; van Eldik, Christopher/0000-0001-9669-645X; Venter, Christo/0000-0002-2666-4812; Casanova, Sabrina/0000-0002-6144-9122; Anton, Gisela/0000-0003-2039-4724; Johannesson, Gudlaugur/0000-0003-1458-7036; Loparco, Francesco/0000-0002-1173-5673; Gargano, Fabio/0000-0002-5055-6395; Moskalenko, Igor/0000-0001-6141-458X; Mazziotta, Mario /0000-0001-9325-4672; Torres, Diego/0000-0002-1522-9065; Drury, Luke/0000-0002-9257-2270; Moulin, Emmanuel/0000-0003-4007-0145; Chadwick, Paula/0000-0002-1468-2685; giommi, paolo/0000-0002-2265-5003; Kneiske, Tanja M./0000-0002-3210-6200; Tramacere, Andrea/0000-0002-8186-3793; Rowell, Gavin/0000-0002-9516-1581; Baldini, Luca/0000-0002-9785-7726; Lenain, Jean-Philippe/0000-0001-7284-9220; Maxted, Nigel/0000-0003-2762-8378; Punch, Michael/0000-0002-4710-2165; Sushch, Iurii/0000-0002-2814-1257; Bordas, Pol/0000-0002-0266-8536; Cutini, Sara/0000-0002-1271-2924; Gasparrini, Dario/0000-0002-5064-9495; de Ona Wilhelmi, Emma/0000-0002-5401-0744; Frailis, Marco/0000-0002-7400-2135; Daniel, Michael/0000-0002-8053-7910; de los Reyes Lopez, Raquel/0000-0003-0485-9552; Caraveo, Patrizia/0000-0003-2478-8018; Komin, Nukri/0000-0003-3280-0582; Sgro', Carmelo/0000-0001-5676-6214; SPINELLI, Paolo/0000-0001-6688-8864; Rando, Riccardo/0000-0001-6992-818X; Bastieri, Denis/0000-0002-6954-8862; Omodei, Nicola/0000-0002-5448-7577; Pesce-Rollins, Melissa/0000-0003-1790-8018; Giroletti, Marcello/0000-0002-8657-8852 FU CAPES Foundation, Ministry of Education of Brazil; Namibian authorities; University of Namibia; German Ministry for Education and Research (BMBF) [DLR 50OR0906]; Max Planck Society; French Ministry for Research; CNRS-IN2P3; CNRS; UK Science and Technology Facilities Council (STFC); IPNP of the Charles University; Polish Ministry of Science and Higher Education; South African Department of Science and Technology; National Research Foundation; Istituto Nazionale di Astrofisica in Italy; Centre National d'Etudes Spatiales in France; RXTE FX Supported by CAPES Foundation, Ministry of Education of Brazil.; The support of the Namibian authorities and of the University of Namibia in facilitating the construction and operation of H.E.S.S. is gratefully acknowledged, as is the support by the German Ministry for Education and Research (BMBF), the Max Planck Society, the French Ministry for Research, the CNRS-IN2P3 and the Astroparticle Interdisciplinary Programme of the CNRS, the UK Science and Technology Facilities Council (STFC), the IPNP of the Charles University, the Polish Ministry of Science and Higher Education, the South African Department of Science and Technology and National Research Foundation, and by the University of Namibia. We appreciate the excellent work of the technical support staff in Berlin, Durham, Hamburg, Heidelberg, Palaiseau, Paris, Saclay, and in Namibia in the construction and operation of the equipment.; Additional support for science analysis during the operations phase is gratefully acknowledged from the Istituto Nazionale di Astrofisica in Italy and the Centre National d'Etudes Spatiales in France.; The authors acknowledge the support by the RXTE and Swift teams for providing ToO observations and the use of the public HEASARC software packages. S.K. and S.W. acknowledge support from the BMBF through grant DLR 50OR0906. NR 43 TC 7 Z9 7 U1 1 U2 13 PU EDP SCIENCES S A PI LES ULIS CEDEX A PA 17, AVE DU HOGGAR, PA COURTABOEUF, BP 112, F-91944 LES ULIS CEDEX A, FRANCE SN 0004-6361 EI 1432-0746 J9 ASTRON ASTROPHYS JI Astron. Astrophys. PD SEP PY 2011 VL 533 AR A110 DI 10.1051/0004-6361/201016170 PG 9 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 823ZN UT WOS:000295168100110 ER PT J AU Lemoine-Goumard, M Zavlin, VE Grondin, MH Shannon, R Smith, DA Burgay, M Camilo, F Cohen-Tanugi, J Freire, PCC Grove, JE Guillemot, L Johnston, S Keith, M Kramer, M Manchester, RN Michelson, PF Parent, D Possenti, A Ray, PS Renaud, M Thorsett, SE Weltevrede, P Wolff, MT AF Lemoine-Goumard, M. Zavlin, V. E. Grondin, M-H Shannon, R. Smith, D. A. Burgay, M. Camilo, F. Cohen-Tanugi, J. Freire, P. C. C. Grove, J. E. Guillemot, L. Johnston, S. Keith, M. Kramer, M. Manchester, R. N. Michelson, P. F. Parent, D. Possenti, A. Ray, P. S. Renaud, M. Thorsett, S. E. Weltevrede, P. Wolff, M. T. TI Discovery of gamma- and X-ray pulsations from the young and energetic PSR J1357-6429 with Fermi and XMM-Newton SO ASTRONOMY & ASTROPHYSICS LA English DT Article DE pulsars: individual: PSR J1357-6429; gamma rays: general; pulsars: general ID LARGE-AREA TELESCOPE; MILLISECOND PULSARS; SPACE-TELESCOPE; POLARIZATION; EMISSION; MISSION; CATALOG; LAT AB Context. Since the launch of the Fermi satellite, the number of known gamma-ray pulsars has increased tenfold. Most gamma-ray detected pulsars are young and energetic, and many are associated with TeV sources. PSR J1357-6429 is a high spin-down power pulsar ((E) over dot = 3.1 x 10(36) erg s(-1)), discovered during the Parkes multibeam survey of the Galactic plane, with significant timing noise typical of very young pulsars. In the very-high-energy domain (E > 100 GeV), H. E. S. S. has reported the detection of the extended source HESS J1356-645 (intrinsic Gaussian width of 12') whose centroid lies 7' from PSR J1357-6429. Aims. We search for gamma- and X-ray pulsations from this pulsar, characterize the neutron star emission and explore the environment of PSR J1357-6429. Methods. Using a rotational ephemeris obtained with 74 observations made with the Parkes telescope at 1.4 GHz, we phase-fold more than two years of gamma-ray data acquired by the Large Area Telescope on-board Fermi as well as those collected with XMM-Newton, and perform gamma-ray spectral modeling. Results. Significant gamma- and X-ray pulsations are detected from PSR J1357-6429. The light curve in both bands shows one broad peak. Gamma-ray spectral analysis of the pulsed emission suggests that it is well described by a simple power-law of index 1.5 +/- 0.3(stat) +/- 0.3(syst) with an exponential cut-off at 0.8 +/- 0.3(stat) +/- 0.3(syst) GeV and an integral photon flux above 100 MeV of (6.5 +/- 1.6(stat) +/- 2.3(syst)) x 10(-8) cm(-2) s(-1). The X-ray spectra obtained from the new data provide results consistent with previous work. Upper limits on the gamma-ray emission from its potential pulsar wind nebula (PWN) are also reported. Conclusions. Assuming a distance of 2.4 kpc, the Fermi LAT energy flux yields a gamma-ray luminosity for PSR J1357-6429 of L-gamma = (2.13 +/- 0.25(stat) +/- 0.83(syst)) x 10(34) erg s(-1), consistent with an L-gamma proportional to root(E) over dot relationship. The Fermi non-detection of the pulsar wind nebula associated with HESS J1356-645 provides new constraints on the electron population responsible for the extended TeV emission. C1 [Lemoine-Goumard, M.; Smith, D. A.] Univ Bordeaux 1, Ctr Etudes Nucl Bordeaux Gradignan, CNRS IN2P3, F-33175 Gradignan, France. [Lemoine-Goumard, M.] NASA MSFC VP62, Space Sci Lab, Univ Space Res Assoc, Huntsville, AL 35805 USA. [Zavlin, V. E.] Univ Tubingen, Inst Astron & Astrophys, D-72076 Tubingen, Germany. [Grondin, M-H] CSIRO Astron & Space Sci, Australia Telescope Natl Facil, Epping, NSW 1710, Australia. [Shannon, R.; Johnston, S.; Keith, M.; Manchester, R. N.] INAF Cagliari Astron Observ, I-09012 Capoterra, CA, Italy. [Burgay, M.; Possenti, A.] Columbia Univ, Columbia Astrophys Lab, New York, NY 10027 USA. [Camilo, F.] Univ Montpellier 2, Lab Univers & Particules Montpellier, CNRS IN2P3, Montpellier, France. [Cohen-Tanugi, J.; Renaud, M.] Max Planck Inst Radioastron, D-53121 Bonn, Germany. [Freire, P. C. C.; Guillemot, L.; Kramer, M.] USN, Res Lab, High Energy Space Environm Branch, Washington, DC 20375 USA. [Grove, J. E.; Ray, P. S.; Wolff, M. T.] Univ Manchester, Jodrell Bank Ctr Astrophys, Sch Phys & Astron, Manchester M13 9PL, Lancs, England. [Kramer, M.; Weltevrede, P.] Stanford Univ, WW Hansen Expt Phys Lab, Kavli Inst Particle Astrophys & Cosmol, Dept Phys, Stanford, CA 94305 USA. [Kramer, M.; Weltevrede, P.] Stanford Univ, SLAC Natl Accelerator Lab, Stanford, CA 94305 USA. [Michelson, P. F.] George Mason Univ, Coll Sci, Ctr Earth Observing & Space Res, Fairfax, VA 22030 USA. [Parent, D.] Univ Calif Santa Cruz, Santa Cruz Inst Particle Phys, Dept Phys, Santa Cruz, CA 95064 USA. [Parent, D.] Univ Calif Santa Cruz, Dept Astron & Astrophys, Santa Cruz, CA 95064 USA. RP Lemoine-Goumard, M (reprint author), Univ Bordeaux 1, Ctr Etudes Nucl Bordeaux Gradignan, CNRS IN2P3, F-33175 Gradignan, France. EM lemoine@cenbg.in2p3.fr; vyacheslav.zavlin-1@nasa.gov; grondin@astro.uni-tuebingen.de; Ryan.Shannon@csiro.au; smith@cenbg.in2p3.fr OI Shannon, Ryan/0000-0002-7285-6348; Burgay, Marta/0000-0002-8265-4344; Ray, Paul/0000-0002-5297-5278 FU Commonwealth Government; Nataliya Ivanova FX The Parkes radio telescope is part of the Australia Telescope, which is funded by the Commonwealth Government for operation as a National Facility managed by CSIRO. We thank our colleagues for their assistance with the radio timing observations.; V.E.Z. is grateful to Nataliya Ivanova for discussions and support. NR 33 TC 13 Z9 13 U1 0 U2 3 PU EDP SCIENCES S A PI LES ULIS CEDEX A PA 17, AVE DU HOGGAR, PA COURTABOEUF, BP 112, F-91944 LES ULIS CEDEX A, FRANCE SN 0004-6361 J9 ASTRON ASTROPHYS JI Astron. Astrophys. PD SEP PY 2011 VL 533 AR A102 DI 10.1051/0004-6361/201117413 PG 6 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 823ZN UT WOS:000295168100102 ER PT J AU Migliori, G Grandi, P Torresi, E Dermer, C Finke, J Celotti, A Mukherjee, R Errando, M Gargano, F Giordano, F Giroletti, M AF Migliori, G. Grandi, P. Torresi, E. Dermer, C. Finke, J. Celotti, A. Mukherjee, R. Errando, M. Gargano, F. Giordano, F. Giroletti, M. TI Implications for the structure of the relativistic jet from multiwavelength observations of NGC 6251 SO ASTRONOMY & ASTROPHYSICS LA English DT Article DE galaxies: jets; galaxies: active; gamma rays: galaxies; galaxies: individual: NGC 6251 ID LARGE-AREA TELESCOPE; ACTIVE GALACTIC NUCLEI; RADIO GALAXY NGC-6251; GAMMA-RAY EMISSION; SPECTRAL ENERGY-DISTRIBUTION; FAST TEV VARIABILITY; BL-LACERTAE OBJECTS; MASSIVE BLACK-HOLES; XMM-NEWTON VIEW; FR-I AB NGC 6251 is a luminous radio galaxy approximate to 104 Mpc away that was detected significantly with the Fermi Gamma-ray Space Telescope, and before that with EGRET (onboard the Compton Gamma-ray Observatory). Different observational constraints favor a nuclear origin for the gamma-ray emission. Here we present a study of the spectral energy distribution of the core of NGC 6251, and give results of modeling in the one-zone synchrotron/SSC framework. The SSC model provides a good description of the radio to gamma-ray emission but, as for other misaligned sources, predicts a lower Lorentz factor (Gamma similar to 2.4) than typically found when modeling blazars. If the blazar unification scenario is correct, this seems to point to the presence of at least two emitting regions in these objects, one with a higher and one with a lower Lorentz factor. The solution of a structured jet, with a fast moving spine surrounded by a slow layer, is explored and the consequences of the two models for the jet energetics and evolution are discussed. C1 [Migliori, G.; Celotti, A.] SISSA Int Sch Adv Studies, I-34136 Trieste, Italy. [Migliori, G.] Harvard Smithsonian Ctr Astrophys, Cambridge, MA 02138 USA. [Grandi, P.; Torresi, E.] INAF, Ist Astrofis & Fis Cosm Bologna, I-40129 Bologna, Italy. [Torresi, E.] Univ Bologna, Dipartimento Astron, I-40127 Bologna, Italy. [Dermer, C.; Finke, J.] USN, Div Space Sci, Res Lab, Washington, DC 20375 USA. [Mukherjee, R.; Errando, M.] Columbia Univ Barnard Coll, Dept Phys & Astron, New York, NY 10027 USA. [Gargano, F.; Giordano, F.] Ist Nazl Fis Nucl, Sez Bari, I-70126 Bari, Italy. [Giordano, F.] Univ Politecn Bari, Dipartimento Fis M Merlin, I-70126 Bari, Italy. [Giroletti, M.] INAF Ist Radioastron, I-40129 Bologna, Italy. RP Migliori, G (reprint author), SISSA Int Sch Adv Studies, Via Bonomea 265, I-34136 Trieste, Italy. EM migliori@head.cfa.harvard.edu RI Gargano, Fabio/O-8934-2015; OI Gargano, Fabio/0000-0002-5055-6395; Grandi, Paola/0000-0003-1848-6013; Errando, Manel/0000-0002-1853-863X; Giroletti, Marcello/0000-0002-8657-8852; TORRESI, ELEONORA/0000-0002-5201-010X FU [GO0-11133X] FX This research has made use of the NASA/IPAC Extragalactic Database (NED) which is operated by the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space Administration. The authors would like to thanks the ASI Science Data Center (ASDC) for providing on-line facilities for the Swift/XRT data analysis. G.M. research is supported by Chandra grant GO0-11133X. NR 84 TC 9 Z9 9 U1 0 U2 3 PU EDP SCIENCES S A PI LES ULIS CEDEX A PA 17, AVE DU HOGGAR, PA COURTABOEUF, BP 112, F-91944 LES ULIS CEDEX A, FRANCE SN 0004-6361 J9 ASTRON ASTROPHYS JI Astron. Astrophys. PD SEP PY 2011 VL 533 AR A72 DI 10.1051/0004-6361/201116808 PG 11 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 823ZN UT WOS:000295168100072 ER PT J AU Nagarathnam, K Massey, D Opeka, M AF Nagarathnam, Karthik Massey, Dennis Opeka, Mark TI PROPERTIES OF REFRACTORY METALS AND ALLOYS FABRICATED BY COMBUSTION-DRIVEN HIGH-PRESSURE POWDER COMPACTION SO INTERNATIONAL JOURNAL OF POWDER METALLURGY LA English DT Article; Proceedings Paper CT 8th International Conference on Tungsten, Refractory and Hardmaterials CY MAY 18-21, 2011 CL San Francisco, CA AB Details of the high-pressure combustion-driven powder compaction (CDC) process are presented with particular reference to the consolidation of refractory metal and alloy powders. Rapid load cycles (ms) at pressures up to 2,069 MPa (150 tsi) result in high-green-density net- or near-net-shape parts that exhibit minimal shrinkage during sintering and fine-grain equiaxed microstructures. CDC tungsten and rhenium-base alloys retain strength levels >172 MPa (25,000 psi) at 1,927 degrees C. As an example of the utility of CDC, the performance of tungsten and molybdenum in X-ray targets is assessed. The properties of CDC refractory metals and alloys offer potential for new commercial applications in the energy, electronics, defense, and biomedical sectors. C1 [Nagarathnam, Karthik; Massey, Dennis] UTRON Kinet LLC, Manassas, VA 20110 USA. [Opeka, Mark] USN, Ctr Surface Warfare, Carderock, MD USA. RP Nagarathnam, K (reprint author), UTRON Kinet LLC, 9441 Innovat Dr, Manassas, VA 20110 USA. EM Karthik@utronkinetics.com NR 25 TC 0 Z9 0 U1 0 U2 4 PU AMER POWDER METALLURGY INST PI PRINCETON PA 105 COLLEGE ROAD EAST, PRINCETON, NJ 08540 USA SN 0888-7462 J9 INT J POWDER METALL JI Int. J. Powder Metall. PD SEP-OCT PY 2011 VL 47 IS 5 BP 23 EP 31 PG 9 WC Metallurgy & Metallurgical Engineering SC Metallurgy & Metallurgical Engineering GA 828LG UT WOS:000295501900005 ER PT J AU Dobrokhodov, V Kaminer, I Kitsios, I Xargay, E Hovakimyan, N Cao, CY Gregory, IM Valavani, L AF Dobrokhodov, Vladimir Kaminer, Isaac Kitsios, Ioannis Xargay, Enric Hovakimyan, Naira Cao, Chengyu Gregory, Irene M. Valavani, Lena TI Experimental Validation of L-1 Adaptive Control: The Rohrs Counterexample in Flight SO JOURNAL OF GUIDANCE CONTROL AND DYNAMICS LA English DT Article; Proceedings Paper CT AIAA Guidance, Navigation, and Control Conference CY AUG 10-13, 2009 CL Chicago, IL SP Amer Inst Aeronaut & Astronaut (AIAA) ID OUTPUT-FEEDBACK CONTROLLER; SYSTEMS; ROBUSTNESS; DYNAMICS; STABILIZATION; EXCITATION AB This paper presents flight-test results that examine the performance and robustness properties of an L-1 control augmentation loop implemented onboard a small unmanned aerial vehicle. The framework used for in-flight control evaluation is based on the Rohrs counterexample, a benchmark problem presented in the early 1980s, to show the limitations of adaptive controllers developed at that time. Hardware-in-the-loop simulations and flight-test results confirm the ability of the L-1 flight control system to maintain stability and predictable performance of the closed-loop adaptive system in the presence of general (artificially injected) unmodeled dynamics. The results demonstrate the advantages of L-1 control as a robust adaptive control architecture with the potential of facilitating the transition of adaptive control into advanced flight control systems. C1 [Dobrokhodov, Vladimir; Kitsios, Ioannis] USN, Postgrad Sch, Dept Mech & Aerosp Engn, Cpt HAF, Monterey, CA 93943 USA. [Xargay, Enric; Hovakimyan, Naira] Univ Illinois, Dept Aerosp Engn, Urbana, IL 61801 USA. [Cao, Chengyu] Univ Connecticut, Dept Mech Engn, Storrs, CT 06269 USA. [Gregory, Irene M.] NASA Langley Res Ctr, Dynam Syst & Controls Branch, Hampton, VA 23681 USA. [Valavani, Lena] Hellen Space Syst SA, Athens 15451, Greece. RP Dobrokhodov, V (reprint author), USN, Postgrad Sch, Dept Mech & Aerosp Engn, Cpt HAF, Monterey, CA 93943 USA. EM vldobr@nps.edu; kaminer@nps.edu; ikitsios@nps.edu; xargay@illinois.edu; nhovakim@illinois.edu; ccao@engr.uconn.edu; irene.m.gregory@nasa.gov; valavani@mit.edu RI Dobrokhodov, Vladimir/C-3443-2009 NR 35 TC 10 Z9 11 U1 0 U2 8 PU AMER INST AERONAUT ASTRONAUT PI RESTON PA 1801 ALEXANDER BELL DRIVE, STE 500, RESTON, VA 22091-4344 USA SN 0731-5090 J9 J GUID CONTROL DYNAM JI J. Guid. Control Dyn. PD SEP-OCT PY 2011 VL 34 IS 5 BP 1311 EP 1328 DI 10.2514/1.50683 PG 18 WC Engineering, Aerospace; Instruments & Instrumentation SC Engineering; Instruments & Instrumentation GA 825BZ UT WOS:000295247200003 ER PT J AU Hayat, AM Tribble, DR Sanders, JW Faix, DJ Shiau, D Armstrong, AW Riddle, MS AF Hayat, Aatif M. Tribble, David R. Sanders, John W. Faix, Dennis J. Shiau, Danny Armstrong, Adam W. Riddle, Mark S. TI Knowledge, Attitudes, and Practice of Travelers' Diarrhea Management among Frontline Providers SO JOURNAL OF TRAVEL MEDICINE LA English DT Article ID OPERATIONS IRAQI FREEDOM; ANTIMICROBIAL THERAPY; ENDURING FREEDOM; EVIDENCE BASE; US MILITARY; EPIDEMIOLOGY; PREVENTION; LOPERAMIDE; IMPACT; POPULATIONS AB Background. Many studies have found acute gastrointestinal infections to be among the most likely reason for clinic visits among forward deployed soldiers and are considered a significant contributor to morbidity in this population. This occurs despite the controlled food and water distribution systems under which military populations operate. Furthermore, recent studies have indicated that providers often fail to appropriately identify and treat the typical causes of these infections. To adequately address this issue, an assessment of gaps in knowledge, practice, and management of acute diarrhea in deployed troops was conducted. Methods. A multiple-choice survey was developed by clinical researchers with expertise in travelers' diarrhea (TD) and provided to a convenience sample of clinical providers with a broad range of training and operational experience. The survey evaluated provider's knowledge of TD along with their ability to identify etiologies of various syndromic categories of acute gastrointestinal infections. Providers were also queried on selection of treatment approaches to a variety of clinical-based scenarios. Results. A total of 117 respondents completed the survey. Most were aware of the standard definition of TD (77%); however, their knowledge about the epidemiology was lower, with less than 24% correctly answering questions on etiology of diarrhea, and 31% believing that a viral pathogen was the primary cause of watery diarrhea during deployment. Evaluation of scenario-based responses showed that 64% of providers chose not to use antibiotics to treat moderate TD. Furthermore, 19% of providers felt that severe inflammatory diarrhea was best treated with hydration only while 25% felt hydration was the therapy of choice for dysentery. Across all provider types, three practitioner characteristics appeared to be related to better scores on responses to the nine management scenarios: having a Doctor of Medicine or Doctor of Osteopathy degree, greater knowledge of TD epidemiology, and favorable attitudes toward antimotility or antibiotic therapy. Conclusion. Results from this survey support the need for improving knowledge and management of TD among deploying providers. The information from this study should be considered to support the establishment and dissemination of military diarrhea-management guidelines to assist in improving the health of military personnel. C1 [Hayat, Aatif M.] Walter Reed Army Inst Res, Silver Spring, MD USA. [Tribble, David R.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA. [Sanders, John W.] Naval Med Res Ctr Detachment, Lima, Peru. [Faix, Dennis J.] USN, Hlth Res Ctr, San Diego, CA 92152 USA. [Shiau, Danny] USN, Bur Med & Surg, Washington, DC USA. [Armstrong, Adam W.] US Naval Med Res Unit 3, Cairo, Egypt. [Riddle, Mark S.] USN, Med Res Ctr, Enter Dis Dept, Silver Spring, MD 20910 USA. RP Riddle, MS (reprint author), USN, Med Res Ctr, Enter Dis Dept, 503 Robert Grant Ave, Silver Spring, MD 20910 USA. EM mark.riddle@med.navy.mil RI Riddle, Mark/A-8029-2011 NR 22 TC 4 Z9 4 U1 0 U2 1 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1195-1982 J9 J TRAVEL MED JI J. Travel Med. PD SEP-OCT PY 2011 VL 18 IS 5 BP 310 EP 317 DI 10.1111/j.1708-8305.2011.00538.x PG 8 WC Medicine, General & Internal SC General & Internal Medicine GA 818DI UT WOS:000294730700004 PM 21896094 ER PT J AU Pressman, P Clemens, R AF Pressman, Peter Clemens, Roger TI FOOD, MEDICINE & HEALTH SO FOOD TECHNOLOGY LA English DT Editorial Material C1 [Pressman, Peter] USN, CDR, Med Corps, Washington, DC 20350 USA. [Pressman, Peter] Task Force Business & Stabil Operat, Expeditionary Med, Crystal City, VA USA. [Clemens, Roger] ETHorn, La Mirada, CA USA. RP Pressman, P (reprint author), USN, CDR, Med Corps, Washington, DC 20350 USA. EM drpressman@gmail.com; rclemens@ethorn.com NR 0 TC 0 Z9 0 U1 0 U2 0 PU INST FOOD TECHNOLOGISTS PI CHICAGO PA 525 WEST VAN BUREN, STE 1000, CHICAGO, IL 60607-3814 USA SN 0015-6639 J9 FOOD TECHNOL-CHICAGO JI Food Technol. PD SEP PY 2011 VL 65 IS 9 BP 24 EP 24 PG 1 WC Food Science & Technology SC Food Science & Technology GA 824MT UT WOS:000295206700010 ER PT J AU Wheeler, B AF Wheeler, Brannon TI Muslims in the West after 9/11: Religion, Politics and Law SO INTERNATIONAL STUDIES REVIEW LA English DT Book Review C1 [Wheeler, Brannon] USN Acad, Ctr Middle E & Islamic Studies, Annapolis, MD USA. RP Wheeler, B (reprint author), USN Acad, Ctr Middle E & Islamic Studies, Annapolis, MD USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1521-9488 J9 INT STUD REV JI Int. Stud. Rev. PD SEP PY 2011 VL 13 IS 3 BP 521 EP 522 PG 2 WC International Relations; Political Science SC International Relations; Government & Law GA 822VN UT WOS:000295078200025 ER PT J AU Glaser, DJ Rahman, AS AF Glaser, Darrell J. Rahman, Ahmed S. TI Human Capital and Technological Transition: Insights from the US Navy SO JOURNAL OF ECONOMIC HISTORY LA English DT Article ID GROWTH; TOURNAMENTS; PROMOTION; EDUCATION; SELECTION; WAGE AB We explore the effects of human capital on workers during the latter nineteenth century by examining the U.S. Navy. Naval officers belonged either to a regular or an engineer corps and had tasks assigned for their specialized training. We compile education and career data for officers from Naval Academy and navy registers for the years 1858 to 1907. Wage premia for "engineer-skilled" officers deteriorated over their careers; more traditionally skilled officers enjoyed higher gains in earnings and more frequent promotions. This compelled those with engineering skills to leave the service early, hindering the navy's capacity to further technologically develop. C1 [Glaser, Darrell J.; Rahman, Ahmed S.] USN Acad, Dept Econ, Annapolis, MD 21402 USA. RP Glaser, DJ (reprint author), USN Acad, Dept Econ, 589 McNair Rd, Annapolis, MD 21402 USA. EM dglaser@usna.edu; rahman@usna.edu NR 36 TC 2 Z9 2 U1 1 U2 3 PU CAMBRIDGE UNIV PRESS PI NEW YORK PA 32 AVENUE OF THE AMERICAS, NEW YORK, NY 10013-2473 USA SN 0022-0507 J9 J ECON HIST JI J. Econ. Hist. PD SEP PY 2011 VL 71 IS 3 BP 704 EP 729 DI 10.1017/S0022050711001896 PG 26 WC Economics; History; History Of Social Sciences SC Business & Economics; History; Social Sciences - Other Topics GA 823GZ UT WOS:000295111800006 ER PT J AU Devlin, JJ Kircher, S Kozen, BG Littlejohn, LF Johnson, AS AF Devlin, John J. Kircher, Sara Kozen, Buddy G. Littlejohn, Lanny F. Johnson, Andrew S. TI COMPARISON OF ChitFlex (R), CELOX (TM), AND QuikClot (R) IN CONTROL OF HEMORRHAGE SO JOURNAL OF EMERGENCY MEDICINE LA English DT Article DE hemostatic agent; trauma; combat; hemorrhage; swine ID EXTREMITY ARTERIAL HEMORRHAGES; 2 ADVANCED DRESSINGS; HEMOSTATIC EFFICACY; COMBAT OPERATIONS; SWINE; INJURY; MODEL; AGENTS; SURVIVAL AB Background: Exsanguinating extremity wounds remain the primary source of battlefield mortality. Operating forces employ three agents in Iraq: HemCon (R) (Hem Con Medical Technologies, Inc., Portland, OR), QuikClot (R) (Z-Medica Corporation, Wallingford, CT), and CELOX (TM) (SAM Medical, Tualatin, OR). Anecdotal reports suggest that these agents are less useful on small entrance, linear-tract injuries. ChitFlex (R) (Hem Con Medical Technologies, Inc., Portland, OR) has been introduced but is untested. Study Objectives: To compare the equivalency of the ChitoFlex (R) dressing, QuikClot ACS+(TM) dressing, CELOX (TM), and standard gauze in their effectiveness to control bleeding from non-cavitary groin wounds. Methods: Forty-eight swine were randomly assigned to one of four treatment groups: standard gauze dressing (SD), ChitoFlex (R) dressing (CF), QuikClot (R) ACS+(TM) dressing (QC), and CELOX (TM) dressing (CX). A groin injury with limited vessel access was created in each animal. Subjects were resuscitated with 500 mL of hetastarch. The primary endpoint was 180-min survival. Secondary endpoints included total blood loss in mL/kg, incidence of re-bleeding, survival times among the animals that did not survive for 180 min, failure to achieve initial hemostasis, incidence of recurrent bleeding, time to initial re-bleeding, amount of re-bleeding, and mass of residual hematoma. Results: Survival occurred in 10 of 12 SD animals, 10 of 12 CF animals, 10 of 12 QC animals, and 9 of 12 CX animals. No statistically significant difference was found. Conclusion: In our study of limited-access extremity bleeding, ChitoFlex (R) performed equally well in mitigating blood loss and promoting survival. The ChitoFlex (R) dressing is an equally effective alternative to currently available hemostatic agents. However, no agents were superior to standard gauze in our model of limited access. Published by Elsevier Inc. C1 [Devlin, John J.; Kircher, Sara; Kozen, Buddy G.; Littlejohn, Lanny F.; Johnson, Andrew S.] Naval Med Ctr Portsmouth, Dept Emergency Med, Portsmouth, VA 23708 USA. RP Devlin, JJ (reprint author), Naval Med Ctr Portsmouth, Dept Emergency Med, 620 John Paul Jones Circle, Portsmouth, VA 23708 USA. FU HemCon Medical Technologies, Inc. [CRADA 2542] FX This study was funded by HemCon Medical Technologies, Inc. (CRADA 2542). None of the authors have received salary from the funding company. None of the authors are spokespersons for, paid consultants for, or stockholders in the funding company. The authors thank the nursing and hospital corpstaff of the Department of Emergency Medicine and the veterinary staff of the Clinical Investigations and Research Department, Naval Medical Center Portsmouth, VA. The authors would also like to thank Petty Officer Tanya Zamarripa for her logistical support and Dr. John Kircher for his statistical assistance. NR 17 TC 22 Z9 23 U1 1 U2 20 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 0736-4679 J9 J EMERG MED JI J. Emerg. Med. PD SEP PY 2011 VL 41 IS 3 BP 237 EP 245 DI 10.1016/j.jemermed.2009.02.017 PG 9 WC Emergency Medicine SC Emergency Medicine GA 824IX UT WOS:000295196700001 PM 19345045 ER PT J AU Kim, W Baker, C Villalobos, G Frantz, J Shaw, B Lutz, A Sadowski, B Kung, F Hunt, M Sanghera, J Aggarwal, I AF Kim, Woohong Baker, Colin Villalobos, Guillermo Frantz, Jesse Shaw, Brandon Lutz, Austin Sadowski, Bryan Kung, Frederic Hunt, Machael Sanghera, Jasbinder Aggarwal, Ishwar TI Synthesis of High Purity Yb3+-Doped Lu2O3 Powder for High Power Solid-State Lasers SO JOURNAL OF THE AMERICAN CERAMIC SOCIETY LA English DT Article ID COMBUSTION SYNTHESIS; SPINEL AB We have synthesized high-purity Yb3+-doped Lu2O3 powder by the coprecipitation method. We have demonstrated that the recrystallization of the metal nitrates greatly improve the chemical purity of the resulting oxides. From thermogravimetry and differential thermal analysis study, we have calculated the approximate formula of the oxinitrate precipitate precursor as Lu1.8Yb0.2(OH)(5.44)(NO3)(0.56).0.58H(2)O. Fine and soft agglomerate powders were obtained after calcinations. We have shown that the powder is mainly in the form of polycrystalline soft agglomerates composed with 15-20 nm size crystals. The resulting ceramic showed higher transparency (close to theoretical limit) compared with the ones fabricated with commercial powders. C1 [Kim, Woohong; Baker, Colin; Villalobos, Guillermo; Frantz, Jesse; Shaw, Brandon; Lutz, Austin; Sanghera, Jasbinder; Aggarwal, Ishwar] USN, Res Lab, Washington, DC 20375 USA. [Sadowski, Bryan] Global Strategies Grp, Crofton, MD 21114 USA. [Kung, Frederic; Hunt, Machael] Univ Res Fdn, Greenbelt, MD 20770 USA. RP Kim, W (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM rick.kim@nrl.navy.mil RI Baker, Colin/I-6657-2015 FU Joint Technology Office for High Energy Lasers (JTO-HEL); Office of Naval Research (ONR) FX This work was financially supported by the Joint Technology Office for High Energy Lasers (JTO-HEL) and the Office of Naval Research (ONR). NR 14 TC 20 Z9 20 U1 1 U2 13 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0002-7820 J9 J AM CERAM SOC JI J. Am. Ceram. Soc. PD SEP PY 2011 VL 94 IS 9 BP 3001 EP 3005 DI 10.1111/j.1551-2916.2011.04485.x PG 5 WC Materials Science, Ceramics SC Materials Science GA 824QB UT WOS:000295215900052 ER PT J AU De Gregorio, BT Stroud, RM Cody, GD Nittler, LR Kilcoyne, ALD Wirick, S AF De Gregorio, Bradley T. Stroud, Rhonda M. Cody, George D. Nittler, Larry R. Kilcoyne, A. L. David Wirick, Sue TI Correlated microanalysis of cometary organic grains returned by Stardust SO METEORITICS & PLANETARY SCIENCE LA English DT Article ID X-RAY SPECTROMICROSCOPY; TRANSMISSION ELECTRON-MICROSCOPY; INTERPLANETARY DUST PARTICLES; MOLECULAR-CLOUD MATERIAL; INNER-SHELL EXCITATION; ISOTOPIC COMPOSITIONS; 81P/WILD 2; INFRARED-SPECTROSCOPY; HYPERVELOCITY CAPTURE; CORE EXCITATION AB Carbonaceous matter in Stardust samples returned from comet 81P/Wild 2 is observed to contain a wide variety of organic functional chemistry. However, some of this chemical variety may be due to contamination or alteration during particle capture in aerogel. We investigated six carbonaceous Stardust samples that had been previously analyzed and six new samples from Stardust Track 80 using correlated transmission electron microscopy (TEM), X-ray absorption near-edge structure spectroscopy (XANES), and secondary ion mass spectroscopy (SIMS). TEM revealed that samples from Track 35 containing abundant aliphatic XANES signatures were predominantly composed of cometary organic matter infilling densified silica aerogel. Aliphatic organic matter from Track 16 was also observed to be soluble in the epoxy embedding medium. The nitrogen-rich samples in this study (from Track 22 and Track 80) both contained metal oxide nanoparticles, and are likely contaminants. Only two types of cometary organic matter appear to be relatively unaltered during particle capture. These are (1) polyaromatic carbonyl-containing organic matter, similar to that observed in insoluble organic matter (IOM) from primitive meteorites, interplanetary dust particles (IDPs), and in other carbonaceous Stardust samples, and (2) highly aromatic refractory organic matter, which primarily constitutes nanoglobule-like features. Anomalous isotopic compositions in some of these samples also confirm their cometary heritage. There also appears to be a significant labile aliphatic component of Wild 2 organic matter, but this material could not be clearly distinguished from carbonaceous contaminants known to be present in the Stardust aerogel collector. C1 [De Gregorio, Bradley T.; Stroud, Rhonda M.] USN, Mat Sci & Technol Div, Res Lab, Washington, DC USA. [De Gregorio, Bradley T.] NASA Johnson Space Ctr, ESCG, Houston, TX USA. [Cody, George D.] Carnegie Inst Sci, Geophys Lab, Washington, DC 20015 USA. [Nittler, Larry R.] Carnegie Inst Sci, Dept Terr Magnetism, Washington, DC 20015 USA. [Kilcoyne, A. L. David] Lawrence Berkeley Natl Lab, Adv Light Source, Berkeley, CA USA. [Wirick, Sue] Brookhaven Natl Lab, Natl Synchrotron Light Source, Upton, NY 11973 USA. RP De Gregorio, BT (reprint author), USN, Mat Sci & Technol Div, Res Lab, Washington, DC USA. EM brad.degregorio@gmail.com RI De Gregorio, Bradley/B-8465-2008; Kilcoyne, David/I-1465-2013; Stroud, Rhonda/C-5503-2008 OI De Gregorio, Bradley/0000-0001-9096-3545; Stroud, Rhonda/0000-0001-5242-8015 FU Office of Naval Research; NASA; NASA Astrobiology Institute; U.S. Department of Energy; Natural Sciences and Engineering Research Council of Canada; National Research Council Canada; Canadian Institutes of Health Research; Province of Saskatchewan; Western Economic Diversification Canada; University of Saskatchewan FX This work was funded by the Office of Naval Research, NASA Discovery Data Analysis and Origins of Solar Systems Program, and NASA Astrobiology Institute. This research was conducted while the primary author held a National Research Council Research Associateship at the U.S. Naval Research Laboratory. Use of the Advanced Light Source and the National Synchrotron Light Source was supported by the U.S. Department of Energy. Use of the Canadian Light Source was supported by the Natural Sciences and Engineering Research Council of Canada, the National Research Council Canada, the Canadian Institutes of Health Research, the Province of Saskatchewan, Western Economic Diversification Canada, and the University of Saskatchewan. The authors gratefully acknowledge the support of Thomas Zega and Nabil Bassim with the acquisition of STXM data. NR 85 TC 16 Z9 16 U1 1 U2 26 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 1086-9379 EI 1945-5100 J9 METEORIT PLANET SCI JI Meteorit. Planet. Sci. PD SEP PY 2011 VL 46 IS 9 BP 1376 EP 1396 DI 10.1111/j.1945-5100.2011.01237.x PG 21 WC Geochemistry & Geophysics SC Geochemistry & Geophysics GA 822MY UT WOS:000295053300010 ER PT J AU Garbis, N Romeo, AA Van Thiel, G Ghodadra, N Provencher, MT Cole, BJ Verma, N AF Garbis, Nickolas Romeo, Anthony A. Van Thiel, Geoffrey Ghodadra, Neil Provencher, Matthew T. Cole, Brian J. Verma, Nikhil TI Clinical Indications and Techniques for the Use of Platelet-Rich Plasma in the Shoulder SO OPERATIVE TECHNIQUES IN SPORTS MEDICINE LA English DT Article DE platelet-rich plasma; superior labrum anterior-posterior; rotator cuff tear; biologic augmentation; operative technique ID RANDOMIZED CONTROLLED-TRIAL; ACHILLES TENDINOPATHY; SPORTS-MEDICINE; INJECTION; SURGERY; GEL AB Platelet-rich plasma (PRP) has recently been a topic of significant interest in the orthopedic community. In addition to the numerous basic science studies regarding the in vitro effects of PRP, there is more literature regarding the use of PRP in the clinical setting. PRP is overall very safe and carries minimal risk for the patient, making it appealing even if there is a small improvement in the final outcome. There appears to be significant interest in using it in the shoulder, particularly in conjunction with rotator cuff repair. We briefly outline the basics of PRP and discuss a few potential operative and nonoperative indications, such as rotator cuff tendinitis, biceps tendinitis, rotator cuff tears, and superior labrum anterior-posterior lesions. Oper Tech Sports Med 19:165-169 (C) 2011 Elsevier Inc. All rights reserved. C1 [Garbis, Nickolas; Romeo, Anthony A.; Van Thiel, Geoffrey; Ghodadra, Neil; Cole, Brian J.; Verma, Nikhil] Rush Univ, Med Ctr, Chicago, IL 60612 USA. [Provencher, Matthew T.] USN, Med Ctr, San Diego, CA 92152 USA. RP Romeo, AA (reprint author), Rush Univ, Med Ctr, 1611 W Harrison, Chicago, IL 60612 USA. EM shoulderelbowdoc@gmail.com OI Romeo, Anthony/0000-0003-4848-3411 NR 18 TC 2 Z9 2 U1 0 U2 4 PU W B SAUNDERS CO-ELSEVIER INC PI PHILADELPHIA PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA SN 1060-1872 J9 OPER TECHN SPORT MED JI Oper. Tech. Sports Med. PD SEP PY 2011 VL 19 IS 3 BP 165 EP 169 DI 10.1053/j.otsm.2011.03.002 PG 5 WC Sport Sciences; Surgery SC Sport Sciences; Surgery GA 823UY UT WOS:000295153200006 ER PT J AU Utz, ER Topp, SG Valentine, JC Brigger, MT AF Utz, Edward R. Topp, Shelby G. Valentine, James C. Brigger, Matthew T. TI Pathology Quiz Case 1: Midline cervical epidermoid cyst SO ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY LA English DT Editorial Material ID NECK MASSES; CHILDREN C1 [Utz, Edward R.; Topp, Shelby G.; Valentine, James C.; Brigger, Matthew T.] USN, San Diego Med Ctr, San Diego, CA 92152 USA. RP Utz, ER (reprint author), USN, San Diego Med Ctr, San Diego, CA 92152 USA. NR 11 TC 0 Z9 0 U1 0 U2 1 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60654-0946 USA SN 0886-4470 J9 ARCH OTOLARYNGOL JI Arch. Otolaryngol. Head Neck Surg. PD SEP PY 2011 VL 137 IS 9 BP 961 EP 963 PG 3 WC Otorhinolaryngology; Surgery SC Otorhinolaryngology; Surgery GA 821VI UT WOS:000295002100018 PM 21930992 ER PT J AU Simon, J Melese, F AF Simon, Jay Melese, Francois TI A Multiattribute Sealed-Bid Procurement Auction with Multiple Budgets for Government Vendor Selection SO DECISION ANALYSIS LA English DT Article DE public procurement; defense acquisition; affordability; vendor selection; multiattribute auctions AB This paper offers a new approach to government vendor selection decisions in major public procurements. A key challenge is for government purchasing agents to select vendors that deliver the best combination of desired nonprice attributes at realistic funding levels. The mechanism proposed in this paper is a multiattribute first-price, sealed-bid procurement auction. It extends traditional price-only auctions to those in which competition takes place exclusively over attribute bundles. The model is a multiattribute auction in which a set of possible budget levels is specified. This model reveals the benefits of defining a procurement alternative in terms of its value to the buyer over a range of possible expenditures, rather than as a single point in budget-value space. This new approach leads to some interesting results. In particular, it suggests that in a fiscally constrained environment, the traditional approach of eliminating dominated alternatives could lead to suboptimal decisions. Finally, an extension of the model explicitly examines the buyer's decision problem under budget uncertainty by applying a utility function assessed over the value measure. C1 [Simon, Jay; Melese, Francois] USN, Postgrad Sch, Def Resources Management Inst, Monterey, CA 93943 USA. RP Simon, J (reprint author), USN, Postgrad Sch, Def Resources Management Inst, Monterey, CA 93943 USA. EM jrsimon@nps.edu; fmelese@nps.edu OI Simon, Jay/0000-0003-3377-0987 NR 30 TC 5 Z9 5 U1 2 U2 10 PU INFORMS PI HANOVER PA 7240 PARKWAY DR, STE 310, HANOVER, MD 21076-1344 USA SN 1545-8490 J9 DECIS ANAL JI Decis. Anal. PD SEP PY 2011 VL 8 IS 3 BP 170 EP 179 DI 10.1287/deca.1110.0210 PG 10 WC Management SC Business & Economics GA 822DY UT WOS:000295025300002 ER PT J AU Guyse, JL Simon, J AF Guyse, Jeffery L. Simon, Jay TI Consistency Among Elicitation Techniques for Intertemporal Choice: A Within-Subjects Investigation of the Anomalies SO DECISION ANALYSIS LA English DT Article DE time preference; discounting; anomalies; procedure invariance ID TIME PREFERENCE; DISCOUNT RATES; SEQUENCES; OUTCOMES; FUTURE; DELAY; RISK; DECISIONS; HEALTH; MONEY AB The equivalence of two elicitation methods (sequences and matching) has been assumed when empirically testing the traditional discounting model even though the respective literature has revealed results that are dependent on the procedure used. Three common anomalies revealed (gain/loss asymmetry, short/long asymmetry, and the absolute magnitude effect) are investigated using the two different methods in a within-subjects experiment. In both procedures, it appears that the participants in this study evaluate monetary outcomes over time differently than the discounting model predicts. Patterns consistent with two of the anomalies (gain/loss and absolute magnitude effect) surface and interact in both elicitation techniques. Finally, a systematic inconsistency exists between the two methods. We observe significantly more consistency between the two elicitation techniques when the outcome is a gain in the relatively far future than when it is a future loss. This may be due to the participants' inability to display a preference for spreading losses, which they revealed in the sequences task, in the matching task. C1 [Guyse, Jeffery L.] Calif State Polytech Univ Pomona, Coll Business Adm, Pomona, CA 91768 USA. [Simon, Jay] USN, Postgrad Sch, Def Resources Management Inst, Monterey, CA 93943 USA. RP Guyse, JL (reprint author), Calif State Polytech Univ Pomona, Coll Business Adm, Pomona, CA 91768 USA. EM jlguyse@csupomona.edu; jrsimon@nps.edu OI Simon, Jay/0000-0003-3377-0987 NR 40 TC 4 Z9 4 U1 5 U2 11 PU INFORMS PI HANOVER PA 7240 PARKWAY DR, STE 310, HANOVER, MD 21076-1344 USA SN 1545-8490 J9 DECIS ANAL JI Decis. Anal. PD SEP PY 2011 VL 8 IS 3 BP 233 EP 246 DI 10.1287/deca.1110.0212 PG 14 WC Management SC Business & Economics GA 822DY UT WOS:000295025300006 ER PT J AU Gutin, A Jacob, P Chu, M Belemjian, PM LeRoy, MR Kraft, RP McDonald, JF AF Gutin, Alexey Jacob, Philip Chu, Michael Belemjian, Paul M. LeRoy, Mitchell R. Kraft, Russell P. McDonald, John F. TI Carry Chains for Ultra High-Speed SiGe HBT Adders SO IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS I-REGULAR PAPERS LA English DT Article DE Adders; bipolar integrated circuits; carry look-ahead; CML; ECL; HBT; SiGe ID CLOCK FREQUENCY; LOGIC-CIRCUITS; TECHNOLOGY; DESIGN; ACCUMULATOR AB Adder structures utilizing SiGe Hetero-junctio Bipolar Transistor (HBT) digital circuits are examined for use in high clock rate digital applications requiring high-speed integer arithmetic. A 4-gate deep test structure for 32-bit addition using a 210 GHz f(T) process has been experimentally verified to operate with 37.5 ps delay or 26.7 GHz speed. The paper documents a unique blend of CML and ECL circuit innovations, which is needed to obtain this result. The chip is estimated to have a power-delay product of 109 ps-W at a device temperature of 85 degrees C. A low power design is shown to have a power-delay product of 48 ps-W at 21.7 GHz. Speed-power trade-offs are explored through pure ECL logic and varying current. Additionally, with next generation SiGe HBTs, this work shows that 40 GHz is achievable at slightly above room temperature. C1 [Gutin, Alexey; Chu, Michael; LeRoy, Mitchell R.; Kraft, Russell P.; McDonald, John F.] Rensselaer Polytech Inst, Troy, NY 12180 USA. [Jacob, Philip] IBM TJ Watson Res Ctr, Yorktown Hts, NY 10598 USA. [Belemjian, Paul M.] USN, Res Lab, Stevensville, MD 21666 USA. RP Gutin, A (reprint author), Rensselaer Polytech Inst, Troy, NY 12180 USA. EM alexeygutin@gmail.com FU DARPA/MARCO/NYSTAR Interconnect Focus Center; DARPA HPCS/IBM PERCS [HBCH3039004]; DARPA/SPAWAR/IBM 3DI [N66001-0408032]; SRC CSR [G00553]; National Science Foundation [1031440, 0333314] FX This work was supported in part by DARPA/MARCO/NYSTAR Interconnect Focus Center, DARPA HPCS/IBM PERCS under Contract HBCH3039004, in part by DARPA/SPAWAR/IBM 3DI under Programs no. N66001-0408032, in part by the SRC CSR under Grant G00553, in part by the National Science Foundation under Grant 1031440, and in part by the National Science Foundation under Grant 0333314. This paper was recommended by Associate Editor A. Strollo. NR 33 TC 7 Z9 7 U1 0 U2 3 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1549-8328 J9 IEEE T CIRCUITS-I JI IEEE Trans. Circuits Syst. I-Regul. Pap. PD SEP PY 2011 VL 58 IS 9 BP 2201 EP 2210 DI 10.1109/TCSI.2011.2112850 PG 10 WC Engineering, Electrical & Electronic SC Engineering GA 820GN UT WOS:000294893800023 ER PT J AU Calame, JP AF Calame, J. P. TI Simulation of polarization, energy storage, and hysteresis in composite dielectrics containing nonlinear inclusions SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID BARIUM-TITANATE; BREAKDOWN STRENGTH; ELECTROACTIVE POLYMERS; MECHANICAL-PROPERTIES; INSULATOR COMPOSITES; PERCOLATION; CONSTANT; MODEL; PERMITTIVITY; CAPACITORS AB Finite difference quasi-electrostatic modeling is used to predict the dielectric behavior of composites consisting of spherical inclusions having nonlinear dielectric polarization behavior that are dispersed in a background linear dielectric matrix. The inclusion nonlinearities are parameterized by a hyperbolic tangent model that includes hysteresis. Computations of composite polarization and energy storage versus applied field and inclusion filling fraction are presented for ordered and random geometries. Electric field statistics are investigated with regard to localized intensification in the matrix, which is relevant to breakdown, and with regard to remnant fields in the inclusions, which is associated with hysteresis. Inclusion saturation behavior is found to cause dramatic departures from the predictions of linear theory, resulting in reduced energy storage in the composites and the existence of optimum filling fractions. Considering various competing factors, an energy storage of 10-12 J/cm(3) at applied fields of 300-350 V/mu m could be feasible in a composite composed of a linear matrix with a dielectric constant of 12 containing volumetric filling fraction 0.3-0.4 of inclusions with a low field dielectric constant of 1200 and a saturation polarization of 0.15 Cm(-2). In spite of significant inclusion hysteresis, the composites displayed only minor overall hysteresis behavior, with>94% recoverable energy being typical, provided the filling fraction was below percolation. With sufficiently high inclusion hysteresis, a bimodal distribution in the polarizations and fields within the inclusions appeared during downswing, manifesting itself as spontaneously organized regions of oppositely aligned polarization that resemble domains. [doi:10.1063/1.3633763] C1 USN, Res Lab, Washington, DC 20375 USA. RP Calame, JP (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM jeffrey.calame@nrl.navy.mil NR 68 TC 7 Z9 7 U1 1 U2 28 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0021-8979 J9 J APPL PHYS JI J. Appl. Phys. PD SEP 1 PY 2011 VL 110 IS 5 AR 054107 DI 10.1063/1.3633763 PG 14 WC Physics, Applied SC Physics GA 821IP UT WOS:000294968600108 ER PT J AU Mohammad, SN AF Mohammad, S. Noor TI General hypothesis for nanowire synthesis. I. Extended principles and evidential (experimental and theoretical) demonstration SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID CHEMICAL-VAPOR-DEPOSITION; MOLECULAR-BEAM EPITAXY; LIQUID-SOLID MECHANISM; CATALYZED SILICON NANOWIRES; GALLIUM NITRIDE NANOWIRES; SINGLE-CRYSTAL NANOWIRES; GAN NANOWIRES; SEMICONDUCTOR NANOWIRES; CONTROLLED GROWTH; GE NANOWIRES AB Nanowires, nanotubes, and nanodots (quantum dots) are nanomaterials (NMTs). While nanodots are miniaturized nanowires, nanotubes are hollow nanowires. A universal model for basic science of the synthesis and characteristics of NMTs must be established. To achieve this goal, a general hypothesis has been presented. This hypothesis makes use of the concept of droplets from seeds, the fundamentals of the adhesive properties of droplets, and a set of droplet characteristics. Fundamentals underlying the droplet formation from nanoparticle seeds under various physicochemical and thermodynamic conditions have been articulated. A model of thermodynamic imbalance of seeds at the growth temperature has been formulated. The dependence of thermodynamic imbalance on parameters such as surface energy, temperature, seed dimension, etc. has been described. The role of thermodynamic imbalance of seeds and of the foreign element catalytic agent (FECA) on NMT growth has been examined. Three different NMT growths, namely, FECA-free NMT growth; FECA-mediated non-eutectic NMT growth; and FECA-mediated eutectic NMT growth, have been considered. FECA-free NMT growth, and non-eutectic but FECA-mediated NMT growth, have been assumed to involve nanopores, grains, and grain boundaries in the seed. The basic science of all the NMT growths utilizes the concept of the creation of tiny component droplets (CODs). Extensive evidential (experimental and theoretical) demonstration of the hypothesis has been put forth. Both theoretical and experimental results lend support to the hypothesis. Calculated results address the roles of both the FECA-mediated and FECA-free droplets for NMT growths. The basics of multiple nucleation and biphasic structures have been spelled out. Possible relationship between the activation energy and the precursor decomposition on the droplet surface at the lowest possible temperature has been elucidated. The differences between the eutectic and no-eutectic seeds, the importance of thermodynamic imbalances in the creation of nanopores inside seeds, and the physicochemical reasons of nanowire growth at temperatures far below the seed's eutectic temperature (and/or melting temperature) have been revealed. Experimental evidences, particularly for CODs, droplets, dipole moment of the seeds (droplets), immovability of droplets, multiple nucleation, biphasic structures, etc., quantify the validity of the hypothesis. (C) 2011 American Institute of Physics. [doi:10.1063/1.3608127] C1 [Mohammad, S. Noor] Sciencotech, Washington, DC 20001 USA. [Mohammad, S. Noor] USN, Res Lab, Washington, DC 20375 USA. RP Mohammad, SN (reprint author), Sciencotech, 780 Girard St NW, Washington, DC 20001 USA. EM snmohammad2002@yahoo.com NR 140 TC 13 Z9 13 U1 2 U2 26 PU AMER INST PHYSICS PI MELVILLE PA 1305 WALT WHITMAN RD, STE 300, MELVILLE, NY 11747-4501 USA SN 0021-8979 EI 1089-7550 J9 J APPL PHYS JI J. Appl. Phys. PD SEP 1 PY 2011 VL 110 IS 5 AR 054311 DI 10.1063/1.3608127 PG 30 WC Physics, Applied SC Physics GA 821IP UT WOS:000294968600122 ER PT J AU Mohammad, SN AF Mohammad, S. Noor TI General hypothesis for nanowire synthesis. II: Universality SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID CHEMICAL-VAPOR-DEPOSITION; LIQUID-SOLID MECHANISM; SINGLE-CRYSTAL NANOWIRES; MODIFIED DROPLET EPITAXY; SILICON NANOWIRES; SEMICONDUCTOR NANOWIRES; GAN NANOWIRES; QUANTUM DOTS; CONTROLLED GROWTH; HYDROTHERMAL SYNTHESIS AB A universal model for basic science of nanowire, nanotube, and nanodot syntheses by the solid-phase, liquid-phase, and vapor-phase mechanisms must be established. To our knowledge, the syntheses of these nanomaterials by the solid-liquid-solid (SLS) and fluid-liquid-solid (FLS) mechanisms have not been understood well. Extensive investigations of the basic features of SLS and FLS mechanisms for nanowire synthesis in the framework of general hypothesis put forth in the preceding paper have been carried out. These have explained why nanowires grown by the SLS mechanism are almost always amorphous. These have explained also why nanowires produced by the catalyst-mediated FLS mechanism have diameters almost always smaller than the diameters of catalyst seed. SLS growth is believed to be a high-temperature process. The actual temperature for this process has been examined. Concept of component seeds (CSDs), component droplets (CODs) from CSDs, and droplets from CODs, has been exploited for the investigations. Evidential (experimental and theoretical) demonstration of the hypothesis for the SLS and FLS growths of nanowires has been carried out. Possible relationship between the activation energy and the precursor decomposition on the droplet surface at the lowest possible temperature has been examined. Evidences of the role of dipole moment in the catalyst-mediated and catalyst-free FLS growth of nanowires, and of the role of droplets in the multiple nucleation of nanowires have been articulated. Evidences have also been presented to highlight the importance of the concentration gradient of the nanowire species and the motive force resulting from this concentration gradient. Quantum dots are miniaturized nanowires. Shortcomings of the conventional methods for large-scale quantum dot synthesis have been discussed. The usefulness of the self-catalytic mechanism for large-scale synthesis of the quantum dots has been elaborated. The importance of thermodynamic imbalance of seeds in nonmaterial growths has been established. Droplet-free scenario for nanowire growth has been envisioned. Ground rules for nanowire heterostructures have been proposed. Experimental results support the findings and demonstrations. The investigations appear to reveal a unified synthetic route of all nanomaterials (e. g., nanowires, nanotubes, and nanodots). They suggest that growths of these nanomaterials may be explained just from one single platform. (C) 2011 American Institute of Physics. [doi:10.1063/1.3608129] C1 [Mohammad, S. Noor] Sciencotech, Washington, DC 20001 USA. [Mohammad, S. Noor] USN, Res Lab, Washington, DC 20375 USA. RP Mohammad, SN (reprint author), Sciencotech, 780 Girard St NW, Washington, DC 20001 USA. EM snmohammad2002@yahoo.com NR 85 TC 7 Z9 7 U1 2 U2 26 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0021-8979 J9 J APPL PHYS JI J. Appl. Phys. PD SEP 1 PY 2011 VL 110 IS 5 AR 054312 DI 10.1063/1.3608129 PG 28 WC Physics, Applied SC Physics GA 821IP UT WOS:000294968600123 ER PT J AU Jung, HS Yang, WI Km, MS Lee, SY Moeckly, BH Claassen, JH AF Jung, Ho Sang Yang, Woo Il Km, Myung Su Lee, Sang Young Moeckly, Brian H. Claassen, John. H. TI Anomalous Suppression of the Microwave Penetration Depth due to Enhanced Microwave Conductivity in 39-K MgB2 Films SO JOURNAL OF THE KOREAN PHYSICAL SOCIETY LA English DT Article DE Penetration depth; Microwave conductivity; MgB2; YBa2Cu3O7-delta; Superconductor film ID INTRINSIC SURFACE IMPEDANCE; THIN-FILMS AB We study the temperature dependences of the microwave in-plane penetration depths at 38 GHz (lambda(ab) (38 GHz)) and 40 GHz (lambda(ab) (40 GHz)) for a YBCO film with a critical temperature (T-C) of 91 K and a MgB2 film with a T-C of 39 K, respectively, for which two TE021-mode sapphire resonators are used for the measurements. The lambda(ab) (40 GHz) appears to be anomalously suppressed in the MgB2 film at temperatures below 0.8T(C), with variations in the lambda(ab) (40 GHZ) with increasing temperature appearing to be significantly less than those in the in-plane penetration depth measured at 10 kHz (lambda(ab) (10 kHz)) by using the mutual inductance method. The suppressed lambda(ab) (38 GHz) of the MgB2 film is attributed to enhanced quasiparticle conductivity, which results in a significant screening of the electromagnetic waves due to the quasiparticles in the MgB2 film. We discuss the quasiparticle screening effects in the MgB2 film in comparison with those in a YBCO film. C1 [Jung, Ho Sang; Yang, Woo Il; Km, Myung Su; Lee, Sang Young] Konkuk Univ, Dept Phys, Seoul 143701, South Korea. [Jung, Ho Sang; Yang, Woo Il; Km, Myung Su; Lee, Sang Young] Konkuk Univ, Ctr Wireless Transmiss Technol, Seoul 143701, South Korea. [Moeckly, Brian H.] Superconductor Technol Inc, Santa Barbara, CA 93111 USA. [Claassen, John. H.] USN, Res Lab, Washington, DC 20375 USA. RP Jung, HS (reprint author), Konkuk Univ, Dept Phys, Seoul 143701, South Korea. EM sylee@konkuk.ac.kr FU Korean Government (MOEHRD) [KRF-2008-C00245] FX One of the authors (S. Y. Lee) expresses his sincere thanks to Prof. Won Nam Kang for his help in preparing this manuscript. This work has been supported by the Korean Government (MOEHRD), Basic Research Promotion Fund (KRF-2008-C00245). NR 18 TC 1 Z9 1 U1 0 U2 1 PU KOREAN PHYSICAL SOC PI SEOUL PA 635-4, YUKSAM-DONG, KANGNAM-KU, SEOUL 135-703, SOUTH KOREA SN 0374-4884 EI 1976-8524 J9 J KOREAN PHYS SOC JI J. Korean Phys. Soc. PD SEP PY 2011 VL 59 IS 3 BP 2301 EP 2307 DI 10.3938/jkps.59.2301 PG 7 WC Physics, Multidisciplinary SC Physics GA 821JP UT WOS:000294971600023 ER PT J AU Lin, AH Glover, DE Myers, JS AF Lin, Andrew H. Glover, Dennis E. Myers, Joseph S., Jr. TI An Overview of Afghan National Army Critical Care Capabilities SO MILITARY MEDICINE LA English DT Article AB Background: The North Atlantic Treaty Organization created the International Security Assistance Force to help support the growth in capacity and capability of Afghan National Army (ANA). Objective: This article describes the current critical care capabilities of the ANA, which was supported by embedded medical mentors to help build up Afghanistan's medical infrastructure after the fall of the Taliban. Design: We reviewed the experiences of deployed medical mentors in ANA hospitals to report the progress and limitations of the North Atlantic Treaty Organization medical mentoring mission. Results: From October 2008 through November 2009, the continued development of ANA Intensive Care Unit capabilities has decreased mortality from 26.3% to 5.1% despite an increase in admissions from 19 to 78 per month. Conclusions: Significant progress was made in the critical care capabilities of the ANA critical care physicians. The medical mentoring mission is an effective weapon in building the health care capacity of the ANA medical system. C1 [Lin, Andrew H.] USN, Cardiol Clin, San Diego Med Ctr, San Diego, CA 92134 USA. [Glover, Dennis E.] USN Hosp Jacksonville, Jacksonville, FL 32214 USA. [Myers, Joseph S., Jr.] Natl Naval Med Ctr, Bethesda, MD 20889 USA. RP Lin, AH (reprint author), USN, Cardiol Clin, San Diego Med Ctr, 34800 Bob Wilson Dr,Bldg 3,Floor 3, San Diego, CA 92134 USA. NR 3 TC 1 Z9 1 U1 0 U2 1 PU ASSOC MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA SN 0026-4075 J9 MIL MED JI Milit. Med. PD SEP PY 2011 VL 176 IS 9 BP 1003 EP 1006 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA 821KU UT WOS:000294974700010 PM 21987957 ER PT J AU Lebedev, N Trammell, SA Dressick, W Kedziora, GS Griva, I Schnur, JM AF Lebedev, Nikolai Trammell, Scott A. Dressick, Walter Kedziora, Gary S. Griva, Igor Schnur, Joel M. TI Structural Reorganizations Control Intermolecular Conductance and Charge Trapping in Paraquat-Tetraphenylborate Inverse Photochemical Cell SO PHOTOCHEMISTRY AND PHOTOBIOLOGY LA English DT Article ID TRANSFER COMPLEXES; POLYMER; VIOLOGEN; ANIONS; DONOR AB Miniaturization of electronic devices to the level of single molecules requires detailed understanding of the mechanisms of their operation. One of the questions here is the identification of the role of structural alterations in charge separation and stabilization in photoactive complexes. To address this question, we calculate optimized molecular and electronic structures, and optical and vibrational spectra of l,l'-dimethyl 4,4'-bipyridinium-bis tetraphenylborate PQ(BPh4)(2) complex ab initio using density functional theory approach and compare them with the experimentally observed UV-Vis and Raman spectra of the molecules in solid-state films. The results indicate that the association of PQ and BPh4 leads to the formation of an internally ionized structure that is accompanied by the structural reorganization of both PQ (the twisting of pyridinium rings) and BPh4 (phenyl rings rotation) moieties. The quanta of light do not seem to be directly involved in the formation of this ionized structure, but provide energy for fast recombination of the separated charges between BPh4- and PQ(2+). The high efficiency of the dark charge separation and the stabilization of separated charges in the complex permit the using of PQ(BPh4)(2) in various charge-transfer devices like molecular probes, photovoltaic devices or chemical memory units. C1 [Lebedev, Nikolai; Trammell, Scott A.; Dressick, Walter] USN, Res Lab, Ctr Biomol Sci & Engn, Washington, DC 20375 USA. [Kedziora, Gary S.] High Performance Technol, Dayton, OH USA. [Griva, Igor; Schnur, Joel M.] George Mason Univ, Dept Math Sci, Fairfax, VA 22030 USA. RP Lebedev, N (reprint author), USN, Res Lab, Ctr Biomol Sci & Engn, Washington, DC 20375 USA. EM nikolai.lebedev@nrl.navy.mil FU Air Force Office of Scientific Research and Naval Research Laboratory FX This work is supported in part by the Air Force Office of Scientific Research and Naval Research Laboratory base programs. NR 12 TC 5 Z9 5 U1 0 U2 9 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0031-8655 J9 PHOTOCHEM PHOTOBIOL JI Photochem. Photobiol. PD SEP-OCT PY 2011 VL 87 IS 5 BP 1024 EP 1030 DI 10.1111/j.1751-1097.2011.00961.x PG 7 WC Biochemistry & Molecular Biology; Biophysics SC Biochemistry & Molecular Biology; Biophysics GA 822LW UT WOS:000295049700010 PM 21699547 ER PT J AU Ma, Z Pirlo, RK Wan, Q Yun, JX Yuan, XC Xiang, P Borg, TK Gao, BZ AF Ma, Zhen Pirlo, Russell K. Wan, Qin Yun, Julie X. Yuan, Xiaocong Xiang, Peng Borg, Thomas K. Gao, Bruce Z. TI Laser-guidance-based cell deposition microscope for heterotypic single-cell micropatterning SO BIOFABRICATION LA English DT Article ID MESENCHYMAL STEM-CELLS; OPTICAL TWEEZERS; FORCES; MICROFABRICATION; CARDIOMYOCYTES AB Cell patterning methods enable researchers to control specific homotypic and heterotypic contact-mediated cell-cell and cell-ECM interactions and to impose defined cell and tissue geometries. To micropattern individual cells to specific points on a substrate with high spatial resolution, we have developed a cell deposition microscope based on the laser-guidance technique. We discuss the theory of optical forces for generating laser guidance and the optimization of the optical configuration (NA approximate to 0.1) to manipulate cells with high speed in three dimensions. Our cell deposition microscope is capable of patterning different cell types onto and within standard cell research devices and providing on-stage incubation for long-term cell culturing. Using this cell deposition microscope, rat mesenchymal stem cells from bone marrow were micropatterned with cardiomyocytes into a substrate microfabricated with polydimethylsiloxane on a 22 mm x 22 mm coverglass to form a single-cell coculturing microenvironment, and their electrophysiological property changes were investigated during the coculturing days. C1 [Ma, Zhen; Wan, Qin; Yun, Julie X.; Gao, Bruce Z.] Clemson Univ, Dept Bioengn, COMSET, Clemson, SC 29634 USA. [Pirlo, Russell K.] USN, Res Lab, Washington, DC 20375 USA. [Yuan, Xiaocong] Nankai Univ, Inst Modern Opt, Key Lab Optoelect Informat Sci & Technol, Minist Educ China, Tianjin 300071, Peoples R China. [Xiang, Peng] Shenzhen Univ, Inst Optoelect, Shenzhen, Guangdong, Peoples R China. [Borg, Thomas K.] Med Univ S Carolina, Dept Regenerat Med & Cell Biol, Charleston, SC 29425 USA. RP Gao, BZ (reprint author), Clemson Univ, Dept Bioengn, COMSET, Clemson, SC 29634 USA. EM zgao@clemson.edu FU NIH [SC COBRE P20RR021949, 1k25hl088262-04]; NSF (MRI) [CBET-0923311, SC EPSCoR RII EPS-0903795]; Ministry of Science of China [2008DFA30590]; State Key Laboratory of Precision Measuring Technology and Instruments (Tianjin University) FX This work has been partially supported by NIH (SC COBRE P20RR021949 and Career Award 1k25hl088262-04), NSF (MRI, CBET-0923311 and SC EPSCoR RII EPS-0903795 through SC GEAR program) and the Program for Key International S&T Cooperation Projects of the Ministry of Science of China (2008DFA30590). JXY and BZG would also like to acknowledge the support from the grant established by the State Key Laboratory of Precision Measuring Technology and Instruments (Tianjin University). NR 21 TC 14 Z9 14 U1 0 U2 8 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 1758-5082 J9 BIOFABRICATION JI Biofabrication PD SEP PY 2011 VL 3 IS 3 SI SI AR 034107 DI 10.1088/1758-5082/3/3/034107 PG 8 WC Engineering, Biomedical; Materials Science, Biomaterials SC Engineering; Materials Science GA 821DO UT WOS:000294955200009 PM 21725149 ER PT J AU Ahlbin, JR Gadlage, MJ Atkinson, NM Narasimham, B Bhuva, BL Witulski, AF Holman, WT Eaton, PH Massengill, LW AF Ahlbin, Jonathan R. Gadlage, Matthew J. Atkinson, Nicholas M. Narasimham, Balaji Bhuva, Bharat L. Witulski, Arthur F. Holman, W. Timothy Eaton, Paul H. Massengill, Lloyd W. TI Effect of Multiple-Transistor Charge Collection on Single-Event Transient Pulse Widths SO IEEE TRANSACTIONS ON DEVICE AND MATERIALS RELIABILITY LA English DT Article DE Charge sharing; pulsewidth; radiation environment; single event; single-event transient (SET); soft error ID CMOS; PROPAGATION; LOGIC; WELL AB Heavy-ion data from a 130-nm bulk CMOS process shows a counterproductive result in using a common single-event charge collection mitigation technique. Guard bands, which are well contacts that surround individual transistors, can reduce single-event pulsewidths for normal strikes, but increase them for angled strikes. Calibrated 3-D TCAD mixed-mode modeling has identified a multiple-transistor charge collection mechanism that explains the experimental data, namely that angled strikes result in charge collection in the normally ON device that increases the restoring current on the struck device. C1 [Ahlbin, Jonathan R.; Atkinson, Nicholas M.; Bhuva, Bharat L.; Witulski, Arthur F.; Holman, W. Timothy; Massengill, Lloyd W.] Vanderbilt Univ, Nashville, TN 37235 USA. [Gadlage, Matthew J.] NAVSEA Crane, Crane, IN 47522 USA. [Narasimham, Balaji] Broadcom Corp, Irvine, CA 92617 USA. [Eaton, Paul H.] Microelect Res & Dev Corp, Albuquerque, NM 87110 USA. RP Ahlbin, JR (reprint author), Vanderbilt Univ, 221 Kirkland Hall, Nashville, TN 37235 USA. EM jon.ahlbin@vanderbilt.edu FU DTRA; Cisco Systems FX Manuscript received February 26, 2011; revised April 25, 2011; accepted May 9, 2011. Date of publication May 23, 2011; date of current version September 2, 2011. This work was supported in part by the DTRA Radiation-Hardened Microelectronics Program and Cisco Systems. NR 15 TC 17 Z9 18 U1 2 U2 6 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1530-4388 J9 IEEE T DEVICE MAT RE JI IEEE Trans. Device Mater. Reliab. PD SEP PY 2011 VL 11 IS 3 BP 401 EP 406 DI 10.1109/TDMR.2011.2157506 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA 819UO UT WOS:000294856900006 ER PT J AU Love, CT Dmowski, W Johannes, MD Swider-Lyons, KE AF Love, Corey T. Dmowski, Wojtek Johannes, Michelle D. Swider-Lyons, Karen E. TI Structural originations of irreversible capacity loss from highly lithiated copper oxides SO JOURNAL OF SOLID STATE CHEMISTRY LA English DT Article DE Lithium-ion battery; Cathode; Li2CuO2; Capacity loss; Pair-distribution function ID ELECTROCHEMICAL PROPERTIES; NEUTRON-DIFFRACTION; PHASE-STABILITY; X-RAY; LITHIUM; ENHANCEMENT; MECHANISM; LI3CU2O4; LI2CUO2; LICUO2 AB We use electrochemistry, high-energy X-ray diffraction (XRD) with pair-distribution function analysis (PDF), and density functional theory (DFT) to study the instabilities of Li2CuO2 at varying state of charge. Rietveld refinement of XRD patterns revealed phase evolution from pure Li2CuO2 body-centered orthorhombic (Immm) space group to multiphase compositions after cycling. The PDF showed CuO4 square chains with varying packing during electrochemical cycling. Peaks in the G(r) at the Cu-O distance for delithiated, LiCuO2, showed CuO4 square chains with reduced ionic radius for Cu in the 3+ state. At full depth of discharge to 1.5 V, CuO was observed in fractions greater than the initial impurity level which strongly affects the reversibility of the lithiation reactions contributing to capacity loss. DFT calculations showed electron removal from Cu and O during delithiation of Li2CuO2. Published by Elsevier Inc. C1 [Love, Corey T.; Johannes, Michelle D.; Swider-Lyons, Karen E.] USN, Res Lab, Washington, DC 20375 USA. [Dmowski, Wojtek] Univ Tennessee, Knoxville, TN 37996 USA. RP Love, CT (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM corey.love@nrl.navy.mil FU Office of Naval Research; U.S. Department of Energy (DOE), Office of Science [DE-AC02-06CH11357] FX The authors are grateful to the Office of Naval Research for support of this work. We would like to thank D. Robinson (APS, 6-ID) and Y. Ren (APS,11-ID) for the help with experimental setup. Use of the Advanced Photon Source is supported by the U.S. Department of Energy (DOE), Office of Science, under Contract No. DE-AC02-06CH11357. NR 21 TC 8 Z9 8 U1 11 U2 42 PU ACADEMIC PRESS INC ELSEVIER SCIENCE PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA SN 0022-4596 J9 J SOLID STATE CHEM JI J. Solid State Chem. PD SEP PY 2011 VL 184 IS 9 BP 2412 EP 2419 DI 10.1016/j.jssc.2011.07.007 PG 8 WC Chemistry, Inorganic & Nuclear; Chemistry, Physical SC Chemistry GA 819OH UT WOS:000294835700016 ER PT J AU Penko, AM Slinn, DN Calantoni, J AF Penko, Allison M. Slinn, Donald N. Calantoni, Joseph TI Model for Mixture Theory Simulation of Vortex Sand Ripple Dynamics SO JOURNAL OF WATERWAY PORT COASTAL AND OCEAN ENGINEERING-ASCE LA English DT Article DE Sediment transport; Seabed geometry; Vortex sand ripples; Bedforms; Bottom boundary layer flow; Mixture theory ID OSCILLATORY FLOW; CONCENTRATED SUSPENSIONS; VISCOUS RESUSPENSION; BATCH SEDIMENTATION; PARTICLES; VISCOSITY; GEOMETRY; FLUID; BED; INSTABILITY AB The complex coupled interactions between fluid and sandy sediment on the seafloor are simulated with a three-dimensional bottom boundary layer model (SedMix3D) developed from mixture theory. SedMix3D solves the unfiltered Navier-Stokes equations for a fluid-sediment mixture treated as a single continuum with effective properties that parameterize the fluid-sediment and sediment-sediment interactions including a variable mixture viscosity, a bulk hindered settling velocity, and a shear-induced, empirically calibrated, mixture diffusion term. A sediment flux equation models the concentration of sediment by describing the balance of sediment flux by advection, gravity, and shear-induced diffusion. The grid spacing is on the order of a sediment grain diameter, and simulated flows had maximum free-stream velocities between 20 and 120 cm/s and periods between 2 and 4 s. Modeled ripple geometries ranged from a single ripple to multiple ripples with varying heights, lengths, and steepness. Only noncohesive sediments (d = 0: 04 cm) with the material properties of quartz in water were considered. The model predicted ripple heights and lengths that compare reasonably to existing ripple predictor formulae. SedMix3D also predicts the merging and separation of ripples as they transition from an initial state to an equilibrium state. DOI: 10.1061/(ASCE)WW.1943-5460.0000084. (C) 2011 American Society of Civil Engineers. C1 [Penko, Allison M.; Calantoni, Joseph] USN, Res Lab, Marine Geosci Div, Stennis Space Ctr, MS 39529 USA. [Penko, Allison M.; Slinn, Donald N.] Univ Florida, Dept Civil & Coastal Engn, Gainesville, FL 32611 USA. RP Penko, AM (reprint author), USN, Res Lab, Marine Geosci Div, Stennis Space Ctr, MS 39529 USA. EM allison.penko@nrlssc.navy.mil; slinn@coastal.ufl.edu; joe.calantoni@nrlssc.navy.mil OI Slinn, Donald/0000-0002-2846-6318 FU Office of Naval Research [61153N, 322 CG]; DoD National Defense Science and Engineering; NAVY DSRC; ERDC DSRC FX The first and third authors are supported under base funding to the Naval Research Laboratory from the Office of Naval Research (PE#61153N). Partial support for the first author was provided by the DoD National Defense Science and Engineering Graduate Fellowship Program and by the Office of Naval Research Coastal Geosciences Program Code 322 CG. This work was supported in part by a grant of computer time from the DoD High Performance Computing Modernization Program at the NAVY DSRC and the ERDC DSRC. The authors also thank Dr. Gretchen M. Burdick for her invaluable contribution to the original model source code while a postdoctoral researcher at the University of Florida and Dr. Bret M. Webb for his helpful insight. NR 56 TC 5 Z9 5 U1 0 U2 5 PU ASCE-AMER SOC CIVIL ENGINEERS PI RESTON PA 1801 ALEXANDER BELL DR, RESTON, VA 20191-4400 USA SN 0733-950X J9 J WATERW PORT C-ASCE JI J. Waterw. Port Coast. Ocean Eng.-ASCE PD SEP-OCT PY 2011 VL 137 IS 5 BP 225 EP 233 DI 10.1061/(ASCE)WW.1943-5460.0000084 PG 9 WC Engineering, Civil; Engineering, Ocean; Water Resources SC Engineering; Water Resources GA 818WO UT WOS:000294786800002 ER PT J AU Doyle, JD Gabersek, S Jiang, QF Bernardet, L Brown, JM Dornbrack, A Filaus, E Grubisic, V Kirshbaum, DJ Knoth, O Koch, S Schmidli, J Stiperski, I Vosper, S Zhong, SY AF Doyle, James D. Gabersek, Sasa Jiang, Qingfang Bernardet, Ligia Brown, John M. Doernbrack, Andreas Filaus, Elmar Grubisic, Vanda Kirshbaum, Daniel J. Knoth, Oswald Koch, Steven Schmidli, Juerg Stiperski, Ivana Vosper, Simon Zhong, Shiyuan TI An Intercomparison of T-REX Mountain-Wave Simulations and Implications for Mesoscale Predictability SO MONTHLY WEATHER REVIEW LA English DT Article ID NONHYDROSTATIC ATMOSPHERIC SIMULATION; WEATHER PREDICTION MODELS; LIMITED-AREA MODEL; GRAVITY-WAVES; DOWNSLOPE WINDS; DRAG PARAMETRIZATION; NUMERICAL-SOLUTIONS; SYSTEM ARPS; FLOW; BREAKING AB Numerical simulations of flow over steep terrain using 11 different nonhydrostatic numerical models are compared and analyzed. A basic benchmark and five other test cases are simulated in a two-dimensional framework using the same initial state, which is based on conditions during Intensive Observation Period (IOP) 6 of the Terrain-Induced Rotor Experiment (T-REX), in which intense mountain-wave activity was observed. All of the models use an identical horizontal resolution of 1 km and the same vertical resolution. The six simulated test cases use various terrain heights: a 100-m bell-shaped hill, a 1000-m idealized ridge that is steeper on the lee slope, a 2500-m ridge with the same terrain shape, and a cross-Sierra terrain profile. The models are tested with both free-slip and no-slip lower boundary conditions. The results indicate a surprisingly diverse spectrum of simulated mountain-wave characteristics including lee waves, hydraulic-like jump features, and gravity wave breaking. The vertical velocity standard deviation is twice as large in the free-slip experiments relative to the no-slip simulations. Nevertheless, the no-slip simulations also exhibit considerable variations in the wave characteristics. The results imply relatively low predictability of key characteristics of topographically forced flows such as the strength of downslope winds and stratospheric wave breaking. The vertical flux of horizontal momentum, which is a domain-integrated quantity, exhibits considerable spread among the models, particularly for the experiments with the 2500-m ridge and Sierra terrain. The differences among the various model simulations, all initialized with identical initial states, suggest that model dynamical cores may be an important component of diversity for the design of mesoscale ensemble systems for topographically forced flows. The intermodel differences are significantly larger than sensitivity experiments within a single modeling system. C1 [Doyle, James D.] USN, Res Lab, Marine Meteorol Div, Monterey, CA 93943 USA. [Gabersek, Sasa] UCAR, Monterey, CA USA. [Bernardet, Ligia; Brown, John M.; Koch, Steven] NOAA, Earth Syst Res Lab, Global Syst Div, Boulder, CO USA. [Doernbrack, Andreas] Deutsch Zentrum Luft & Raumfahrt, Inst Phys Atmosphare, Oberpfaffenhofen, Germany. [Filaus, Elmar; Knoth, Oswald] Leibniz Inst Tropospher Res, Leipzig, Germany. [Grubisic, Vanda] Univ Vienna, Vienna, Austria. [Kirshbaum, Daniel J.] Univ Reading, Reading, Berks, England. [Schmidli, Juerg] ETH, Inst Atmospher & Climate Sci, Zurich, Switzerland. [Stiperski, Ivana] Meteorol & Hydrol Serv, Zagreb, Croatia. [Vosper, Simon] Met Off, Exeter, Devon, England. [Zhong, Shiyuan] Michigan State Univ, E Lansing, MI 48824 USA. [Bernardet, Ligia] Univ Colorado, Cooperat Inst Res Environm Sci, Boulder, CO 80309 USA. RP Doyle, JD (reprint author), USN, Res Lab, Marine Meteorol Div, 7 Grace Hopper Ave, Monterey, CA 93943 USA. EM james.doyle@nrlmry.navy.mil RI Schmidli, Juerg/G-9282-2012; Bernardet, Ligia/N-3357-2014; Brown, John/D-3361-2015 OI Schmidli, Juerg/0000-0002-6322-6512; FU Office of Naval Research [0601153N]; Swiss National Science Foundation [PA002-111427]; NSF [ATM-0524891]; Croatian Ministry of Science [004-1193086-3036]; National Science Foundation [ATM-0646299]; National Center of Atmospheric Research FX We acknowledge the contribution of the T-REX scientists, forecasters, staff, NCAR staff, and flight crews. The first three authors acknowledge support through the Office of Naval Research's Program Element 0601153N. J. Schmidli was supported by the Swiss National Science Foundation Grant PA002-111427. ARPS is developed by the Center for Analysis and Prediction of Storms, University of Oklahoma. Brian Jamison provided invaluable assistance with the WRF-ARW runs. In the early stages of this work, Prof. Grubisic was supported by an NSF Grant ATM-0524891 to the Desert Research Institute. Ivana Stiperski acknowledges support of the Croatian Ministry of Science through Grant 004-1193086-3036 to the Croatian Meteorological and Hydrological Service. S. Zhong acknowledges the support of the National Science Foundation Grant ATM-0646299. Drs. Kirshbaum and Zhong's simulations were performed using a supercomputing grant from the National Center of Atmospheric Research, which is sponsored by the National Science Foundation. Computational resources were supported in part by a grant of HPC time from the Department of Defense Major Shared Resource Centers. NR 65 TC 29 Z9 29 U1 0 U2 8 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 USA SN 0027-0644 J9 MON WEATHER REV JI Mon. Weather Rev. PD SEP PY 2011 VL 139 IS 9 BP 2811 EP 2831 DI 10.1175/MWR-D-10-05042.1 PG 21 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA 820UR UT WOS:000294932100009 ER PT J AU Jun, M Szunyogh, I Genton, MG Zhang, FQ Bishop, CH AF Jun, Mikyoung Szunyogh, Istvan Genton, Marc G. Zhang, Fuqing Bishop, Craig H. TI A Statistical Investigation of the Sensitivity of Ensemble-Based Kalman Filters to Covariance Filtering SO MONTHLY WEATHER REVIEW LA English DT Article ID ATMOSPHERIC DATA ASSIMILATION; GLOBAL-MODEL; ERROR; LOCALIZATION; PREDICTION AB This paper investigates the effects of spatial filtering on the ensemble-based estimate of the background error covariance matrix in an ensemble-based Kalman filter (EnKF). In particular, a novel kernel smoothing method with variable bandwidth is introduced and its performance is compared to that of the widely used Gaspari-Cohn filter, which uses a fifth-order kernel function with a fixed localization length. Numerical experiments are carried out with the 40-variable Lorenz-96 model. The results of the experiments show that the nonparametric approach provides a more accurate estimate of the background error covariance matrix than the Gaspari-Cohn filter with any localization length. It is also shown that the Gaspari-Cohn filter tends to provide more accurate estimates of the covariance with shorter localization lengths. However, the analyses obtained by using longer localization lengths tend to be more accurate than those produced by using short localization lengths or the nonparametric approach. This seemingly paradoxical result is explained by showing that localization with longer localization lengths produces filtered estimates whose time mean is the most similar to the time mean of both the unfiltered estimate and the true covariance. This result suggests that a better metric of covariance filtering skill would be one that combined a measure of closeness to the sample covariance matrix for a very large ensemble with a measure of similarity between the climatological averages of the filtered and sample covariance. C1 [Jun, Mikyoung; Genton, Marc G.] Texas A&M Univ, Dept Stat, College Stn, TX 77843 USA. [Szunyogh, Istvan] Texas A&M Univ, Dept Atmospher Sci, College Stn, TX USA. [Zhang, Fuqing] Penn State Univ, Dept Meteorol, University Pk, PA 16802 USA. [Bishop, Craig H.] USN, Res Lab, Marine Meteorol Div, Monterey, CA USA. RP Jun, M (reprint author), Texas A&M Univ, Dept Stat, College Stn, TX 77843 USA. EM mjun@stat.tamu.edu RI Szunyogh, Istvan/G-9248-2012; Zhang, Fuqing/E-6522-2010 OI Zhang, Fuqing/0000-0003-4860-9985 FU National Science Foundation [ATM 0620624]; NSF [ATM 0935538, DMS-1007504]; ONR [N000140910589, N000140410471, 0602435N, BE-435-003] FX Mikyoung Jun, Marc G. Genton, and Fuqing Zhang acknowledge the support from the National Science Foundation (ATM 0620624). Mikyoung Jun's research is also supported by NSF Grant DMS-0906532. Istvan Szunyogh acknowledges the support from NSF (ATM 0935538) and ONR (N000140910589). Marc Genton's research is supported by NSF DMS-1007504. Fuqing Zhang acknowledges the support from ONR Grant N000140410471. Craig H. Bishop acknowledges support from ONR Project Element 0602435N, Project Number BE-435-003. The authors are grateful to Herschel Mitchell (the Editor), Andrew Tangborn, and one anonymous reviewer for valuable comments. NR 33 TC 12 Z9 12 U1 0 U2 7 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 USA SN 0027-0644 J9 MON WEATHER REV JI Mon. Weather Rev. PD SEP PY 2011 VL 139 IS 9 BP 3036 EP 3051 DI 10.1175/2011MWR3577.1 PG 16 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA 820UR UT WOS:000294932100021 ER PT J AU Legler, PM Brey, RN Smallshaw, JE Vitetta, ES Millard, CB AF Legler, Patricia M. Brey, Robert N. Smallshaw, Joan E. Vitetta, Ellen S. Millard, Charles B. TI Structure of RiVax: a recombinant ricin vaccine SO ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY LA English DT Article ID A-CHAIN; PROTECTS MICE; TRANSITION-STATE; DISULFIDE BONDS; CELL EPITOPE; TOXIN; INTOXICATION; ANTIBODIES; STABILITY; PROTEINS AB RiVax is a recombinant protein that is currently under clinical development as part of a human vaccine to protect against ricin poisoning. RiVax includes ricin A-chain (RTA) residues 1-267 with two intentional amino-acid substitutions, V76M and Y80A, aimed at reducing toxicity. Here, the crystal structure of RiVax was solved to 2.1 angstrom resolution and it was shown that it is superposable with that of the ricin toxin A-chain from Ricinus communis with a root-mean-square deviation of 0.6 angstrom over 258 C(alpha) atoms. The RiVax structure is also compared with the recently determined structure of another potential ricin-vaccine immunogen, RTA 1-33/44-198 R48C/T77C. Finally, the locations and solvent-exposure of two toxin-neutralizing B-cell epitopes were examined and it was found that these epitopes are within or near regions predicted to be involved in catalysis. The results demonstrate the composition of the RiVax clinical material and will guide ongoing protein-engineering strategies to develop improved immunogens. C1 [Millard, Charles B.] USA, Med Res & Mat Command, Frederick, MD 21702 USA. [Legler, Patricia M.] USN, Res Labs, Washington, DC 20375 USA. [Brey, Robert N.] Soligenix Inc, Princeton, NJ 08540 USA. [Smallshaw, Joan E.; Vitetta, Ellen S.] Univ Texas SW Med Ctr Dallas, Ctr Canc Immunobiol, Dallas, TX 75390 USA. RP Millard, CB (reprint author), USA, Med Res & Mat Command, Frederick, MD 21702 USA. EM charles.b.millard@us.army.mil FU US Defense Threat Reduction Agency JSTO [S.S.0003_06_WR_B]; National Institutes of Health [U01 A1082120-01] FX This work was funded by the US Defense Threat Reduction Agency JSTO award S.S.0003_06_WR_B (CBM) and National Institutes of Health U01 A1082120-01 (CBM). The opinions or assertions contained herein belong to the authors and are not necessarily the official views of the US Army, US Navy or the US Department of Defense. NR 38 TC 13 Z9 14 U1 2 U2 9 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 0907-4449 J9 ACTA CRYSTALLOGR D JI Acta Crystallogr. Sect. D-Biol. Crystallogr. PD SEP PY 2011 VL 67 BP 826 EP 830 DI 10.1107/S0907444911026771 PN 9 PG 5 WC Biochemical Research Methods; Biochemistry & Molecular Biology; Biophysics; Crystallography SC Biochemistry & Molecular Biology; Biophysics; Crystallography GA 817QR UT WOS:000294689400010 PM 21904036 ER PT J AU Purdy, AP Butcher, RJ AF Purdy, Andrew P. Butcher, Ray J. TI catena-Poly[copper(II)-bis(mu-2-ethyl-5-methylimidazole-4-sulfonato-kapp a N-3(3),O-4:O-4 ')] SO ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE LA English DT Article ID CRYSTAL-STRUCTURE; COORDINATION; COMPLEXES AB In the title compound, [Cu(C6H9N2O3S)(2)](n), the copper(II) ion sits on an inversion center and is chelated by the imidazole N and sulfonate O atoms of two ligands in equatorial positions. O atoms of adjacent molecules coordinate in the axial positions. Jahn-Teller tetragonal distortion is evident in the coordination geometry [Cu-N and Cu-O equatorial distances of 1.971 (3) and 2.045 (2) angstrom, respectively, with a Cu-O axial distance of 2.433 (3) angstrom]. The structure is propagated by an infinite chain of eight-membered (Cu-O-S-O)(2) ring systems along the a axis. Only N-H center dot center dot center dot O hydrogen bonding exists between the chains. C1 [Purdy, Andrew P.] USN, Res Lab, Div Chem, Washington, DC 20375 USA. [Butcher, Ray J.] Howard Univ, Dept Chem, Washington, DC 20059 USA. RP Purdy, AP (reprint author), USN, Res Lab, Div Chem, Code 6120,4555 Overlook Ave SW, Washington, DC 20375 USA. EM andrew.purdy@nrl.navy.mil FU NSF-MRI [CHE-0619278]; Office of Naval Research FX RJB wishes to acknowledge the NSF-MRI program (grant No. CHE-0619278) for funds to purchase the diffractometer, and we thank the Office of Naval Research for financial support. NR 13 TC 0 Z9 0 U1 0 U2 5 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1600-5368 J9 ACTA CRYSTALLOGR E JI Acta Crystallogr. Sect. E.-Struct Rep. Online PD SEP PY 2011 VL 67 BP M1303 EP U1329 DI 10.1107/S160053681103409X PN 9 PG 11 WC Crystallography SC Crystallography GA 817YQ UT WOS:000294714600101 PM 22058889 ER PT J AU DeMers, G Camp, JL Bennett, D AF DeMers, Gerard Camp, Jacob L. Bennett, Donald TI Pneumomediastinum caused by isolated oral-facial trauma SO AMERICAN JOURNAL OF EMERGENCY MEDICINE LA English DT Article ID MINOR MAXILLOFACIAL TRAUMA; SUBCUTANEOUS EMPHYSEMA; MEDIASTINAL EMPHYSEMA; FRACTURE; NECK; SECONDARY; INJURY; FACE AB Pneumomediastinum from isolated blunt or penetrating oral-facial trauma is a rare occurrence, which can be associated with facial fractures or may be iatrogenic. We present two cases caused by high-pressure-induced facial injuries that had very different management and outcomes. The first patient had asymptomatic pneumomediastinum and an uncomplicated recovery, whereas the second had a complicated clinical course requiring extensive surgical debridement. Neither patient developed mediastinitis as a complication of pneumomediastinum. This case series illustrates isolated facial trauma causing pneumomediastinum and reviews the literature over last 20 years for similar cases. The authors advocate emergency department management of pneumomediastinum from facial trauma. C1 [DeMers, Gerard; Bennett, Donald] USN, San Diego Med Ctr, San Diego, CA 92134 USA. [Camp, Jacob L.] USN, Hlth Clin Corpus Christi, Corpus Christi, TX 78419 USA. RP DeMers, G (reprint author), USN, San Diego Med Ctr, San Diego, CA 92134 USA. EM gerard.demers@med.navy.mil; jacob.camp@med.navy.mil; donald.bennett@med.navy.mil NR 27 TC 1 Z9 1 U1 0 U2 0 PU W B SAUNDERS CO-ELSEVIER INC PI PHILADELPHIA PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA SN 0735-6757 J9 AM J EMERG MED JI Am. J. Emerg. Med. PD SEP PY 2011 VL 29 IS 7 AR 841.e3 DI 10.1016/j.ajem.2010.06.022 PG 6 WC Emergency Medicine SC Emergency Medicine GA 818MV UT WOS:000294756700042 PM 20708884 ER PT J AU Scarlett, HP Nisbett, RA Stoler, J Bain, BC Bhatta, MP Castle, T Harbertson, J Brodine, SK Vermund, SH AF Scarlett, Henroy P. Nisbett, Richard A. Stoler, Justin Bain, Brendan C. Bhatta, Madhav P. Castle, Trevor Harbertson, Judith Brodine, Stephanie K. Vermund, Sten H. TI South-to-North, Cross-Disciplinary Training in Global Health Practice: Ten Years of Lessons Learned from an Infectious Disease Field Course in Jamaica SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID EXPERIENCES; PROGRAMS AB Global commerce, travel, and emerging and resurging infectious diseases have increased awareness of global health threats and opportunities for collaborative and service learning. We review course materials, knowledge archives, data management archives, and student evaluations for the first 10 years of an intensive summer field course in infectious disease epidemiology and surveillance offered in Jamaica. We have trained 300 students from 28 countries through collaboration between the University of the West Indies and U.S. partner universities. Participants were primarily graduate students in public health, but also included health professionals with terminal degrees, and public health nurses and inspectors. Strong institutional synergies, committed faculty, an emphasis on scientific and cultural competencies, and use of team-based field research projects culminate in a unique training environment that provides participants with career-developing experiences. We share lessons learned over the past decade, and conclude that South-to-North leadership is critical in shaping transdisciplinary, cross-cultural, global health practice. C1 [Nisbett, Richard A.] Univ S Florida, Coll Publ Hlth, Dept Global Hlth, Tampa, FL USA. [Stoler, Justin] San Diego State Univ, Dept Geog, San Diego, CA 92182 USA. [Brodine, Stephanie K.] San Diego State Univ, Grad Sch Publ Hlth, Div Epidemiol & Biostat, San Diego, CA 92182 USA. Kent State Univ, Sch Publ Hlth, Dept Biostat Environm Hlth Sci & Epidemiol, Kent, OH 44242 USA. [Harbertson, Judith] Naval Hlth Res Ctr, US Mil HIV Res Program, San Diego, CA USA. [Vermund, Sten H.] Vanderbilt Univ, Sch Med, Inst Global Hlth, Nashville, TN 37212 USA. Univ W Indies, Dept Community Hlth & Psychiat, Kingston 7, Jamaica. [Scarlett, Henroy P.] Univ W Indies, Dept Community Hlth & Psychiat, Mona Kingston 7, Jamaica. [Bain, Brendan C.] Univ W Indies Mona, Univ W Indies, HIV AIDS Response Programme UWI HARP,Off Vice Cha, Caribbean HIVAIDS Reg Training Network,Reg Coordi, Kingston 7, Jamaica. [Castle, Trevor] Minist Hlth, Kingston 6, Jamaica. RP Scarlett, HP (reprint author), Univ W Indies, Dept Community Hlth & Psychiat, Mona Kingston 7, Jamaica. EM henpscar@gmail.com; rnisbett@health.usf.edu; stoler@rohan.sdsu.edu; brendan.bain@uwimona.edu.jm; mbhatta@kent.edu; trevicastle@yahoo.com; judith.harbertson@med.navy.mil; sbrodine@mail.sdsu.edu; sten.vermund@vanderbilt.edu RI yan, liu/A-1822-2015; OI yan, liu/0000-0001-8517-1084; Vermund, Sten/0000-0001-7289-8698 NR 22 TC 3 Z9 3 U1 1 U2 8 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD SEP PY 2011 VL 85 IS 3 BP 397 EP 404 DI 10.4269/ajtmh.2011.10-0524 PG 8 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA 816EL UT WOS:000294581400003 PM 21896794 ER PT J AU Balcells, ME Rabagliati, R Garcia, P Poggi, H Oddo, D Concha, M Abarca, K Jiang, J Kelly, DJ Richards, AL Fuerst, PA AF Balcells, M. Elvira Rabagliati, Ricardo Garcia, Patricia Poggi, Helena Oddo, David Concha, Marcela Abarca, Katia Jiang, Ju Kelly, Daryl J. Richards, Allen L. Fuerst, Paul A. TI Endemic Scrub Typhus-like Illness, Chile SO EMERGING INFECTIOUS DISEASES LA English DT Article ID NEIGHBOR-JOINING METHOD; ORIENTIA-TSUTSUGAMUSHI AB We report a case of scrub typhus in a 54-year-old man who was bitten by several terrestrial leeches during a trip to Chiloe Island in southern Chile in 2006. A molecular sample, identified as related to Orientia tsutsugamushi based on the sequence of the 16S rRNA gene, was obtained from a biopsy specimen of the eschar on the patient's leg. Serologic analysis showed immunoglobulin G conversion against O. tsutsugamushi whole cell antigen. This case and its associated molecular analyses suggest that an Orientia-like agent is present in the Western Hemisphere that can produce scrub typhus-like illness. The molecular analysis suggests that the infectious agent is closely related, although not identical, to members of the Orientia sp. from Asia. C1 [Kelly, Daryl J.] Ohio State Univ, Dept Evolut Ecol & Organismal Biol, Columbus, OH 43210 USA. [Balcells, M. Elvira; Rabagliati, Ricardo; Garcia, Patricia; Poggi, Helena; Oddo, David; Concha, Marcela; Abarca, Katia] Pontificia Univ Catolica Chile, Sch Med, Santiago, Chile. [Jiang, Ju; Richards, Allen L.] USN, Med Res Ctr, Silver Spring, MD USA. RP Kelly, DJ (reprint author), Ohio State Univ, Dept Evolut Ecol & Organismal Biol, 388 Aronoff Lab,318 W 12th Ave, Columbus, OH 43210 USA. EM kelly.350@osu.edu RI Valle, Ruben/A-7512-2013 FU Global Emerging Infections Surveillance and Response System, a Division of the Armed Forces Health Surveillance Center [0000188M.0931.001.A0074]; National Institutes of Health, National Eye Institute [EY090703] FX This study was supported by the Global Emerging Infections Surveillance and Response System, a Division of the Armed Forces Health Surveillance Center (work unit no. 0000188M.0931.001.A0074); and National Institutes of Health, National Eye Institute (grant no. EY090703). NR 19 TC 22 Z9 23 U1 1 U2 10 PU CENTERS DISEASE CONTROL PI ATLANTA PA 1600 CLIFTON RD, ATLANTA, GA 30333 USA SN 1080-6040 J9 EMERG INFECT DIS JI Emerg. Infect. Dis PD SEP PY 2011 VL 17 IS 9 BP 1659 EP 1663 DI 10.3201/eid1709.100960 PG 5 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA 817FG UT WOS:000294656100011 PM 21888791 ER PT J AU Melnick, GA Shen, YC Wu, VY AF Melnick, Glenn A. Shen, Yu-Chu Wu, Vivian Yaling TI The Increased Concentration Of Health Plan Markets Can Benefit Consumers Through Lower Hospital Prices SO HEALTH AFFAIRS LA English DT Article ID COSTS; COMPETITION; MEMBERSHIP; OWNERSHIP; REVENUES; PROFIT; CARE AB The long-term trend of consolidation among US health plans has raised providers' concerns that the concentration of health plan markets can depress their prices. Although our study confirmed that, it also revealed a more complex picture. First, we found that 64 percent of hospitals operate in markets where health plans are not very concentrated, and only 7 percent are in markets that are dominated by a few health plans. Second, we found that in most markets, hospital market concentration exceeds health plan concentration. Third, our study confirmed earlier studies showing that greater hospital market concentration leads to higher hospital prices. Fourth, we found that hospital prices in the most concentrated health plan markets are approximately 12 percent lower than in more competitive health plan markets. Overall, our results show that more concentrated health plan markets can counteract the price-increasing effects of concentrated hospital markets, and that-contrary to conventional wisdom-increased health plan concentration benefits consumers through lower hospital prices as long as health plan markets remain competitive. Our findings also suggest that consumers would benefit from policies that maintained competition in hospital markets or that would restore competition to hospital markets that are uncompetitive. C1 [Melnick, Glenn A.; Wu, Vivian Yaling] Univ So Calif, Sch Policy Planning & Dev, Los Angeles, CA 90095 USA. [Shen, Yu-Chu] Naval Postgrad Sch, Grad Sch Business & Publ Policy, Monterey, CA USA. RP Melnick, GA (reprint author), Univ So Calif, Sch Policy Planning & Dev, Los Angeles, CA 90095 USA. EM gmelnick@usc.edu FU Robert Wood Johnson Changes in Health Care Financing and Organization (HCFO) initiative FX External funding for this research was provided by the Robert Wood Johnson Changes in Health Care Financing and Organization (HCFO) initiative. NR 24 TC 16 Z9 16 U1 0 U2 5 PU PROJECT HOPE PI BETHESDA PA 7500 OLD GEORGETOWN RD, STE 600, BETHESDA, MD 20814-6133 USA SN 0278-2715 J9 HEALTH AFFAIR JI Health Aff. PD SEP PY 2011 VL 30 IS 9 BP 1728 EP 1733 DI 10.1377/hlthaff.2010.0406 PG 6 WC Health Care Sciences & Services; Health Policy & Services SC Health Care Sciences & Services GA 817KE UT WOS:000294670400015 PM 21900664 ER PT J AU Hoel, DF Zollner, GE El-Hossary, SS Fawaz, EY Watany, N Hanafi, HA Obenauer, PJ Kirsch, P AF Hoel, D. F. Zollner, G. E. El-Hossary, S. S. Fawaz, E. Y. Watany, N. Hanafi, H. A. Obenauer, P. J. Kirsch, P. TI Comparison of Three Carbon Dioxide Sources on Phlebotomine Sand Fly Capture in Egypt SO JOURNAL OF MEDICAL ENTOMOLOGY LA English DT Article DE compressed CO(2); Phlebotomus papatasi; CO(2) generator system; surveillance; dry ice ID US MILITARY OPERATIONS; TALLIL-AIR-BASE; L-LACTIC ACID; ZOONOTIC CUTANEOUS LEISHMANIASIS; SOUTHERN EGYPT; FLIES; DIPTERA; 1-OCTEN-3-OL; PSYCHODIDAE; AFGHANISTAN AB Lighted Centers for Disease Control and Prevention (CDC) light traps were baited with carbon dioxide (CO(2)) produced from three different sources to compare the efficacy of each in collecting phlebotomine sand flies in Bahrif village, Aswan Governorate, Egypt. Treatments consisted of compressed CO(2) gas released at a rate of 250 ml/min, 1.5 kg of dry ice (replaced daily) sublimating from an insulated plastic container, CO(2) gas produced from a prototype FASTGAS (FG) CO(2) generator system (APTIV Inc., Portland, OR), and a CDC light trap without a CO(2) source. Carbon dioxide was released above each treatment trap's catch opening. Traps were placed in a 4 X 4 Latin square designed study with three replications completed after four consecutive nights in August 2007. During the study, 1,842 phlebotomine sand flies were collected from two genera and five species. Traps collected 1,739 (94.4%) Phlebotomus papatasi (Scopoli), 19 (1.0%) Phlebotomus sergenti, 64 (3.5%) Sergentomyia schwetzi, 16 (0.9%) Sergentomyia palestinensis, and four (0.2%) Sergentomyia tiberiadis. Overall treatment results were dry ice (541) > FG (504) > compressed gas (454) > no CO(2) (343). Total catches of P. papatasi were not significantly different between treatments, although CO(2)-baited traps collected 23-34% more sand flies than the unbaited (control) trap. Results indicate that the traps baited with a prototype CO(2) generator were as attractive as traps supplied with CO(2) sources traditionally used in sand fly surveillance efforts. Field-deployable CO(2) generators are particularly advantageous in remote areas where dry ice or compressed gas is difficult to obtain. C1 [Hoel, D. F.] USN, Marine Corps Publ Hlth Ctr Detachment, Ctr Med Agr & Vet Entomol, Gainesville, FL 32608 USA. [Zollner, G. E.] Walter Reed Army Inst Res, Div Entomol, Silver Spring, MD 20910 USA. [El-Hossary, S. S.; Fawaz, E. Y.; Watany, N.; Hanafi, H. A.; Obenauer, P. J.] US Naval Med Res Unit 3, Cairo, Egypt. [Kirsch, P.] Univ Queensland, Minerals Ind Safety & Hlth Ctr, Sustainable Minerals Inst, St Lucia, Qld 4072, Australia. RP Hoel, DF (reprint author), USN, Marine Corps Publ Hlth Ctr Detachment, Ctr Med Agr & Vet Entomol, 1600 SW 23rd Dr, Gainesville, FL 32608 USA. EM davidfhoel@yahoo.com RI Kirsch, Philipp/F-5740-2011 OI Kirsch, Philipp/0000-0002-9188-5697 FU Deployed War-Fighter Protection Program FX We thank Maria Badra for logistical and administrative support and Rania Kaldas for help with sand fly processing at NAMRU-3. This work was performed under a Cooperative Research and Development Agreement between Walter Reed Army Institute of Research, NAMRU-3, and APTIV Inc., and was supported in part by the Deployed War-Fighter Protection Program. D.F.H. and P.J.O. are military service members, G.E.Z., S.S.E.H., E.Y.F., N. W., and H.A.H. are employees of the U.S. Government, and P. K. is a civilian employee of an Australian university. This work was prepared as part of our official duties. Title 17 U.S.C. 105 provides that "Copyright protection under this title is not available for any work of the United States Government." Title 17 U.S.C. 101 defines a U.S. Government work as a work prepared by a military service member or employee of the U.S. Government as part of that person's official duties. NR 29 TC 6 Z9 6 U1 1 U2 5 PU ENTOMOLOGICAL SOC AMER PI LANHAM PA 10001 DEREKWOOD LANE, STE 100, LANHAM, MD 20706-4876 USA SN 0022-2585 J9 J MED ENTOMOL JI J. Med. Entomol. PD SEP PY 2011 VL 48 IS 5 BP 1057 EP 1061 DI 10.1603/ME11083 PG 5 WC Entomology; Veterinary Sciences SC Entomology; Veterinary Sciences GA 816FX UT WOS:000294585200013 PM 21936325 ER PT J AU Young, RA Benold, T Whitham, J Burge, S AF Young, Richard A. Benold, Terrell Whitham, John Burge, Sandra TI Factors Influencing Work Interference in Patients With Chronic Low Back Pain: A Residency Research Network of Texas (RRNeT) Study SO JOURNAL OF THE AMERICAN BOARD OF FAMILY MEDICINE LA English DT Article DE Analgesics; Depression; Low Back Pain; Occupational Medicine; Practice-based Research ID FEAR-AVOIDANCE BELIEFS; PHYSICAL HEALTH CONSEQUENCES; INTIMATE PARTNER VIOLENCE; PRIMARY-CARE; RISK-FACTORS; QUESTIONNAIRE FABQ; CLINICAL-COURSE; FOLLOW-UP; DISABILITY; DEPRESSION AB Introduction: Chronic low back pain (CLBP) is a disabling and expensive condition commonly seen in family physicians' offices. A complete understanding of factors contributing to patients' return to work remains elusive. Objective: To describe patients with CLBP seen in family physicians' offices and to explore factors interfering with return to work. Subjects: Three hundred sixty outpatients with CLBP for more than 3 months. Setting: Ten participating family physicians' offices of the Residency Research Network of Texas. Primary Outcome: The effect of pain on work effect as measured by a Likert scale. Results: Patients were typically female (72%), overweight or obese (mean body mass index, 33.4), had pain for many years (mean, 13.6 years), and screened positive for recent depressive symptoms (83%). The majority of patients took at least some opioid medication for their pain (59%). Multivariate linear regression analysis found that the largest single contributor to effect on work was the subjects' score on the SF-36 physical function scale (beta = -0.382). Other contributors included average daily pain (beta = 0.189), the frequency of flare-ups of pain (beta = 0.108), the effect of the painful flare-ups (beta = 0.170), and current depressive symptoms (beta = 0.131) (adjusted R(2) for model = 0.535). Age, sex, race/ethnicity, total time the patient has had CLBP, other comorbidities (including a diagnosis of depression), disability status, use of opioids, history of intimate partner violence, social support, and procedures attempted were not predictive. Discussion: Future studies attempting to demonstrate the effectiveness of interventions in CLBP should measure depressive symptoms and the magnitude and effect of painful flare-ups, not just the overall pain score. The majority of CLBP patients seen in these practices take opioids for their pain. Screening and treating for depression may be reasonable for some patients, though evidence of its effectiveness is lacking. (J Am Board Fam Med 2011;24:503-510.) C1 [Young, Richard A.] John Peter Smith Hosp FMRP, Ft Worth, TX 76104 USA. [Benold, Terrell] Austin Acad Family Med, Austin, TX USA. [Whitham, John] USN, Air Stn, Corpus Christi, TX USA. [Burge, Sandra] Univ Texas Hlth Sci Ctr San Antonio, Dept Family Med, San Antonio, TX 78229 USA. RP Young, RA (reprint author), John Peter Smith Hosp FMRP, 1500 S Main, Ft Worth, TX 76104 USA. EM ryoung01@jpshealth.org FU Texas Academy of Family Physicians Foundation; Office of the Medical Dean of the University of Texas Health Science Center at San Antonio FX Funding: This study was funded by the Texas Academy of Family Physicians Foundation and the Office of the Medical Dean of the University of Texas Health Science Center at San Antonio. NR 49 TC 6 Z9 6 U1 5 U2 10 PU AMER BOARD FAMILY MEDICINE PI LEXINGTON PA 2228 YOUNG DR, LEXINGTON, KY 40505 USA SN 1557-2625 J9 J AM BOARD FAM MED JI J. Am. Board Fam. Med. PD SEP-OCT PY 2011 VL 24 IS 5 BP 503 EP 510 DI 10.3122/jabfm.2011.05.100298 PG 8 WC Primary Health Care; Medicine, General & Internal SC General & Internal Medicine GA 817IC UT WOS:000294664300008 PM 21900433 ER PT J AU Gillern, SM Sheppard, FR Evans, KN Graybill, JC Gage, FA Forsberg, JA Dunne, JR Tadaki, DK Elster, EA AF Gillern, Suzanne M. Sheppard, Forest R. Evans, Korboi N. Graybill, J. Christopher Gage, Frederick A. Forsberg, Jonathan A. Dunne, James R. Tadaki, Douglas K. Elster, Eric A. TI Incidence of Pulmonary Embolus in Combat Casualties With Extremity Amputations and Fractures SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Article DE Wounds; Combat; Pulmonary embolus; War ID DEEP-VEIN THROMBOSIS; VENA-CAVA FILTERS; MOLECULAR-WEIGHT HEPARIN; LARGE TRAUMA POPULATION; VENOUS THROMBOEMBOLISM; MAJOR TRAUMA; AGGRESSIVE PROPHYLAXIS; SCREENING PROTOCOL; MULTIPLE TRAUMA; 1602 EPISODES AB Background: The objective of this retrospective study was to determine the incidence of pulmonary embolism (PE) in casualties of wartime extremity wounds and specifically in casualties with a trauma-associated amputation. Methods: Records of all combat-wounded evacuated and admitted between March 1, 2003, and December 31, 2007, were retrospectively reviewed. Continuous and categorical variables were studied with the Student's t test, Fisher's exact test or chi(2) test; multivariate analysis was performed using a stepwise regression logistic model. Results: A total of 1,213 records were reviewed; 263 casualties met the inclusion criteria. One hundred three (41.5%) had amputations and 145 (58.5%) had long-bone fractures not requiring amputation. The observed rate of PE in these 263 casualties was 5.7%. More casualties with amputations, 10 (3.7%), developed PE than those with long-bone fractures in the absence of amputation, 5 (1.9%) (p = 0.045). Casualties with bilateral lower extremity trauma-associated amputations had a significantly higher incidence of PE compared with those sustaining a single amputation (p = 0.023), and the presence of bilateral lower extremity amputations was an independent risk factor for development of a PE (p = 0.007, odds ratio 5.9) (univariate and multivariate analysis, respectively). Conclusion: The cumulative incidence of PE was 5.7%. The incidence of PE is significantly higher with trauma-associated amputation than with extremity long-bone fracture without amputation. Bilateral amputations, multiple long-bone fractures, and pelvic fractures are independent risk factors for the development of PE. The use of aggressive prophylaxis, deep venous thrombosis screening with ultrasound, and use of prophylactic inferior vena cava filters should be considered in this patient population. C1 [Gillern, Suzanne M.; Sheppard, Forest R.; Evans, Korboi N.; Graybill, J. Christopher; Gage, Frederick A.; Forsberg, Jonathan A.; Tadaki, Douglas K.; Elster, Eric A.] USN, Regenerat Med Dept, Med Res Ctr, Silver Spring, MD 20910 USA. [Gillern, Suzanne M.; Sheppard, Forest R.; Graybill, J. Christopher; Gage, Frederick A.; Dunne, James R.; Elster, Eric A.] Walter Reed Natl Mil Med Ctr, Dept Surg, Bethesda, MD USA. [Sheppard, Forest R.; Forsberg, Jonathan A.; Dunne, James R.; Tadaki, Douglas K.; Elster, Eric A.] Uniformed Serv Univ Hlth Sci, Dept Surg, Bethesda, MD USA. [Evans, Korboi N.; Forsberg, Jonathan A.] Walter Reed Natl Mil Med Ctr, Integrated Dept Orthoped & Rehabil, Bethesda, MD USA. RP Elster, EA (reprint author), USN, Regenerat Med Dept, Med Res Ctr, Silver Spring, MD 20910 USA. EM eric.elster@med.navy.mil FU US Navy Bureau of Medicine and Surgery; Office of Naval Research [604771N.0933.001.A0604]; US Navy BUMED Advanced Development Program FX Supported (in part) by the US Navy Bureau of Medicine and Surgery under the Medical Development Program and Office of Naval Research work unit number (604771N.0933.001.A0604). Funding provided by US Navy BUMED Advanced Development Program. NR 32 TC 21 Z9 23 U1 2 U2 2 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA SN 0022-5282 EI 1529-8809 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD SEP PY 2011 VL 71 IS 3 BP 607 EP 612 DI 10.1097/TA.0b013e3182282574 PG 6 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 818MX UT WOS:000294756900022 PM 21908998 ER PT J AU Trieu, A Kayala, MA Burk, C Molina, DM Freilich, DA Richie, TL Baldi, P Felgner, PL Doolan, DL AF Trieu, Angela Kayala, Matthew A. Burk, Chad Molina, Douglas M. Freilich, Daniel A. Richie, Thomas L. Baldi, Pierre Felgner, Philip L. Doolan, Denise L. TI Sterile Protective Immunity to Malaria is Associated with a Panel of Novel P. falciparum Antigens SO MOLECULAR & CELLULAR PROTEOMICS LA English DT Article ID CD8+ T-CELLS; APICAL MEMBRANE ANTIGEN-1; PLASMODIUM-FALCIPARUM; CIRCUMSPOROZOITE PROTEIN; LIVER-STAGE; LIFE-CYCLE; OXIDATIVE STRESS; INTERFERON-GAMMA; CLINICAL MALARIA; SPOROZOITE STAGE AB The development of an effective malaria vaccine remains a global public health priority. Less than 0.5% of the Plasmodium falciparum genome has been assessed as potential vaccine targets and candidate vaccines have been based almost exclusively on single antigens. It is possible that the failure to develop a malaria vaccine despite decades of effort might be attributed to this historic focus. To advance malaria vaccine development, we have fabricated protein microarrays representing 23% of the entire P. falciparum proteome and have probed these arrays with plasma from subjects with sterile protection or no protection after experimental immunization with radiation attenuated P. falciparum sporozoites. A panel of 19 pre-erythrocytic stage antigens was identified as strongly associated with sporozoite-induced protective immunity; 16 of these antigens were novel and 85% have been independently identified in sporozoite and/or liver stage proteomic or transcriptomic data sets. Reactivity to any individual antigen did not correlate with protection but there was a highly significant difference in the cumulative signal intensity between protected and not protected individuals. Functional annotation indicates that most of these signature proteins are involved in cell cycle/DNA processing and protein synthesis. In addition, 21 novel blood-stage specific antigens were identified. Our data provide the first evidence that sterile protective immunity against malaria is directed against a panel of novel P. falciparum antigens rather than one antigen in isolation. These results have important implications for vaccine development, suggesting that an efficacious malaria vaccine should be multivalent and targeted at a select panel of key antigens, many of which have not been previously characterized. Molecular & Cellular Proteomics 10: 10.1074/mcp.M111.007948, 1-15, 2011. C1 [Doolan, Denise L.] Queensland Inst Med Res, Bancroft Ctr, Div Immunol, Brisbane, Qld 4029, Australia. [Kayala, Matthew A.; Baldi, Pierre] Univ Calif Irvine, Sch Informat & Comp Sci, Irvine, CA 92067 USA. [Kayala, Matthew A.; Baldi, Pierre] Univ Calif Irvine, Inst Genom & Bioinformat, Irvine, CA 92067 USA. [Burk, Chad; Felgner, Philip L.] Univ Calif Irvine, Sch Med, Dept Med, Div Infect Dis, Irvine, CA 92697 USA. [Molina, Douglas M.] Antigen Discovery Inc, Irvine, CA 92618 USA. [Freilich, Daniel A.; Richie, Thomas L.] USN, US Mil Malaria Vaccine Program, Med Res Ctr, Silver Spring, MD 20910 USA. [Doolan, Denise L.] Univ Queensland, Sch Med, Brisbane, Qld 4006, Australia. RP Doolan, DL (reprint author), Queensland Inst Med Res, Bancroft Ctr, Div Immunol, 300 Herston Rd,PO Royal Brisbane Hosp, Brisbane, Qld 4029, Australia. EM Denise.Doolan@qimr.edu.au RI Doolan, Denise/F-1969-2015; OI Richie, Thomas/0000-0002-2946-5456 FU National Health and Medical Research Council (Australia) [496600]; National Institute of Allergy and Infectious Diseases [R43AI066791]; National Institutes of Health [5T15LM007743]; National Science Foundation [MRI EIA-0321390]; Pfizer Australia; [62787A.870.F.1432] FX This work was supported by the National Health and Medical Research Council (Australia) grant 496600 and the National Institute of Allergy and Infectious Diseases grant R43AI066791. The bioinformatics and primer design in this work was supported by National Institutes of Health Biomedical Informatics Training Program Grant 5T15LM007743 and National Science Foundation Grant MRI EIA-0321390 to Pierre Baldi and the Institute for Genomics and Bioinformatics. The work of authors affiliated with the Naval Medical Research Center was supported by work unit number 62787A.870.F.1432. DLD is supported by a Pfizer Australia Senior Research Fellowship. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. NR 94 TC 1 Z9 1 U1 0 U2 9 PU AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3996 USA SN 1535-9476 J9 MOL CELL PROTEOMICS JI Mol. Cell. Proteomics PD SEP PY 2011 VL 10 IS 9 DI 10.1074/mcp.M111.007948 PG 15 WC Biochemical Research Methods SC Biochemistry & Molecular Biology GA 818DB UT WOS:000294729200010 ER PT J AU Chu, PY Kelley, JGW Mott, GV Zhang, AJ Lang, GA AF Chu, Philip Y. Kelley, John G. W. Mott, Gregory V. Zhang, Aijun Lang, Gregory A. TI Development, implementation, and skill assessment of the NOAA/NOS Great Lakes Operational Forecast System SO OCEAN DYNAMICS LA English DT Article DE Numerical modeling; Lake forecasts; Coastal nowcast/forecast lake modeling system ID ERIE; MODEL AB The NOAA Great Lakes Operational Forecast System (GLOFS) uses near-real-time atmospheric observations and numerical weather prediction forecast guidance to produce three-dimensional forecasts of water temperature and currents, and two-dimensional forecasts of water levels of the Great Lakes. This system, originally called the Great Lakes forecasting system (GLFS), was developed at The Ohio State University and NOAA's Great Lakes Environmental Research Laboratory (GLERL) in 1989. In 1996, a workstation version of the GLFS was ported to GLERL to generate semi-operational nowcasts and forecasts daily. In 2004, GLFS went through rigorous skill assessment and was transitioned to the National Ocean Service (NOS) Center for Operational Oceanographic Products and Services (CO-OPS) in Silver Spring, MD. GLOFS has been making operational nowcasts and forecasts at CO-OPS since September 30, 2005. Hindcast, nowcast, and forecast evaluations using the NOS-developed skill assessment software tool indicated both surface water levels and temperature predictions passed the NOS specified criteria at a majority of the validation locations with relatively low root mean square error (4-8 cm for water levels and 0.5 to 1A degrees C for surface water temperatures). The difficulty of accurately simulating seiches generated by storms (in particular in shallow lakes like Lake Erie) remains a major source of error in water level prediction and should be addressed in future improvements of the forecast system. C1 [Chu, Philip Y.] USN, Res Lab, Stennis Space Ctr, MS 39529 USA. [Kelley, John G. W.] NOAA NOS CSDL, Silver Spring, MD USA. [Mott, Gregory V.; Zhang, Aijun] NOAA NOS CO OPS, Silver Spring, MD USA. [Lang, Gregory A.] NOAA OAR GLERL, Ann Arbor, MI USA. RP Chu, PY (reprint author), USN, Res Lab, Stennis Space Ctr, MS 39529 USA. EM Philip.chu@nrlssc.navy.mil FU NOS FX The development of the Great Lakes Forecasting System was a joint effort of The Ohio State University (OSU) and NOAA's Great Lakes Environmental Research Laboratory under the direction of Drs. Keith Bedford and David Schwab. Fifteen graduate students, seven faculty, six postdocs, and seven research scientists from OSU have been associated with the development of the system. The transition of the GLCFS from OSU and GLERL to NOS was conducted by the GLOFS System Development and Implementation Team consisting of scientists from GLERL, OSU, CO-OPS, CSDL, and Aqualinks Inc. In particular, the authors would like to thank Drs. Frank Aikman and Mark Vincent at NOS for their support in this project. The archived GLCFS nowcast and forecast used in the skill assessment to fulfill the semi-operational nowcast and forecast scenarios were provided by Greg Lang and David Schwab at NOAA/GLERL. The authors would also like to thank the reviewers for their comments and suggestions. NR 32 TC 4 Z9 4 U1 1 U2 4 PU SPRINGER HEIDELBERG PI HEIDELBERG PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY SN 1616-7341 J9 OCEAN DYNAM JI Ocean Dyn. PD SEP PY 2011 VL 61 IS 9 BP 1305 EP 1316 DI 10.1007/s10236-011-0424-5 PG 12 WC Oceanography SC Oceanography GA 818AO UT WOS:000294721200006 ER PT J AU Jensen, TG AF Jensen, Tommy G. TI Bifurcation of the Pacific North Equatorial Current in a wind-driven model: response to climatological winds SO OCEAN DYNAMICS LA English DT Article DE North Equatorial Current; Bifurcation; North Pacific; Numerical modeling ID INDIAN-OCEAN MODEL; CURRENT SYSTEM; PHILIPPINE COAST; WESTERN BOUNDARY; MINDANAO CURRENT; GWR METHOD; CIRCULATIONS; VARIABILITY; KUROSHIO AB The sensitivity of the bifurcation of the North Equatorial Current in the Pacific to different wind products is investigated. Variations of the bifurcation latitude with season is simulated in a purely wind-driven model and is found to be in agreement with recent observations. The seasonal cycle is nearly independent of the wind climatology, but the annual average latitude depends on the wind stress curl. It is also shown that in the upper ocean, the poleward shift in bifurcation latitude with depth is realistic in our simple model. This implies that given a stratification close to the observed, it is primarily the wind forcing that determines the location of the bifurcation and its seasonal variation. C1 USN, Div Oceanog, Res Lab, Stennis Space Ctr, MS 39529 USA. RP Jensen, TG (reprint author), USN, Div Oceanog, Res Lab, Code 7322, Stennis Space Ctr, MS 39529 USA. EM Tommy.Jensen@nrlssc.navy.mil FU Office of Naval Research; Japan Agency for Marine-Earth Science and Technology through International Pacific Research Center; NSF [OCE00-95906] FX This research was supported by the Office of Naval Research, and in its early phase by the Japan Agency for Marine-Earth Science and Technology through its sponsorship of the International Pacific Research Center, and by NSF grant OCE00-95906. Discussions with Julian McCreary, Toru Miyama, and Tangdong Qu were very helpful. Jan Hafner compiled monthly psuedo-wind stress from QuikSCAT. NR 26 TC 5 Z9 5 U1 1 U2 6 PU SPRINGER HEIDELBERG PI HEIDELBERG PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY SN 1616-7341 J9 OCEAN DYNAM JI Ocean Dyn. PD SEP PY 2011 VL 61 IS 9 BP 1329 EP 1344 DI 10.1007/s10236-011-0427-2 PG 16 WC Oceanography SC Oceanography GA 818AO UT WOS:000294721200008 ER PT J AU Roberts, NC AF Roberts, Nancy C. TI Beyond Smokestacks and Silos: Open-Source, Web-Enabled Coordination in Organizations and Networks SO PUBLIC ADMINISTRATION REVIEW LA English DT Article ID SECTOR KNOWLEDGE NETWORKS; PUBLIC-SERVICES; GOVERNANCE; FORMS; COPRODUCTION; COOPERATION; CHALLENGES; LEADERSHIP AB What accounts for coordination problems? Many mechanisms of coordination exist in both organizations and networks, yet despite their widespread use, coordination challenges persist. Some believe the challenges are growing even more serious. One answer lies in understanding that coordination is not a free good; it is expensive in terms of time, effort, and attention, or what economists call transaction and administrative costs. An alternative to improving coordination is to reduce its costs, yet there is little guidance in the literature to help managers and researchers calculate coordination costs or make design decisions based on cost reductions. This article explores two cases-the U. S. Patent and Trademark Office's Peer-to-Patent pilot program and the online relief effort in Haiti following the devastating earthquake there in 2010-to illustrate the advantages and constraints of using Web 2.0 technology as a mechanism of coordination and a tool for cost reduction. The lessons learned from these cases may off er practitioners and researchers a way out of our "silos" and "smokestacks." C1 Naval Postgrad Sch, Grad Sch Operat & Informat Sci, Monterey, CA USA. RP Roberts, NC (reprint author), Naval Postgrad Sch, Grad Sch Operat & Informat Sci, Monterey, CA USA. EM nroberts@nps.edu NR 94 TC 10 Z9 10 U1 1 U2 19 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0033-3352 EI 1540-6210 J9 PUBLIC ADMIN REV JI Public Adm. Rev. PD SEP-OCT PY 2011 VL 71 IS 5 BP 677 EP 693 DI 10.1111/j.1540-6210.2011.02406.x PG 17 WC Public Administration SC Public Administration GA 817JM UT WOS:000294668300001 ER PT J AU Jansen, E Gallenson, AC AF Jansen, Erik Gallenson, Ann C. TI Practitioner Response to "Beyond Smokestacks and Silos: Open-Source, Web-Enabled Coordination in Organizations and Networks" SO PUBLIC ADMINISTRATION REVIEW LA English DT Editorial Material C1 [Jansen, Erik] USN, Dept Informat Sci, Postgrad Sch, Monterey, CA 93943 USA. [Gallenson, Ann C.] USN, Ctr Execut Educ, Postgrad Sch, Monterey, CA USA. RP Jansen, E (reprint author), USN, Dept Informat Sci, Postgrad Sch, Monterey, CA 93943 USA. EM ejansen@nps.edu; ann@acharlesdesign.com NR 12 TC 1 Z9 1 U1 0 U2 2 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0033-3352 J9 PUBLIC ADMIN REV JI Public Adm. Rev. PD SEP-OCT PY 2011 VL 71 IS 5 BP 694 EP 696 DI 10.1111/j.1540-6210.2011.02407.x PG 3 WC Public Administration SC Public Administration GA 817JM UT WOS:000294668300002 ER PT J AU Longley, C Zimmerman, D AF Longley, Carrick Zimmerman, Douglas TI Practitioner Response to "Beyond Smokestacks and Silos: Open-Source, Web-Enabled Coordination in Organizations and Networks" SO PUBLIC ADMINISTRATION REVIEW LA English DT Editorial Material C1 [Longley, Carrick; Zimmerman, Douglas] Naval Postgrad Sch, Monterey, CA USA. RP Longley, C (reprint author), Naval Postgrad Sch, Monterey, CA USA. EM ctlongle@nps.edu; dwzimmer@nps.edu NR 5 TC 0 Z9 0 U1 0 U2 1 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 0033-3352 J9 PUBLIC ADMIN REV JI Public Adm. Rev. PD SEP-OCT PY 2011 VL 71 IS 5 BP 697 EP 699 DI 10.1111/j.1540-6210.2011.02408.x PG 3 WC Public Administration SC Public Administration GA 817JM UT WOS:000294668300003 ER PT J AU Bestaoui-Spurr, N Edmondson, CA Wintersgill, MC Fontanella, JJ Adams, T AF Bestaoui-Spurr, Naima Edmondson, C. A. Wintersgill, M. C. Fontanella, J. J. Adams, Todd TI Effect of nanoparticles on the dielectric properties of polyimide SO SMART MATERIALS & STRUCTURES LA English DT Article; Proceedings Paper CT 3rd Annual Meeting of the ASME/AIAA Smart Materials, Adaptive Structures, and Intelligent Systems Conference CY SEP 28-OCT 01, 2010 CL Philadelphia, PA SP ASME, Nanotechnol Inst, AIAA ID ALPHA-ZIRCONIUM PHOSPHATE; EPOXY NANOCOMPOSITES AB As part of a search for a better dielectric for use in high energy density capacitors, polyimide (PI) films containing a layered material, zirconium orthophosphate, ZrO(H(2)PO(4))(2)center dot xH(2)O (alpha-ZrP), were fabricated. PI has the advantage that it can be used to very high temperatures. To characterize the materials, x-ray diffraction (XRD), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and dielectric measurements (permittivity, loss and breakdown strength) were made. The permittivity and loss studies were also carried out on both neat PI films and alpha-ZrP. The XRD, DSC and TGA results are consistent with amorphous composites. The effects of water or other impurities were observed in all three kinds of dielectric studies on all three types of material. For example, the relative permittivity of the composites decreased strongly when water was removed from the materials. Nonetheless, some increase in the relative permittivity of the dry nanocomposites was observed. Impurity or water-associated loss peaks were observed in all three types of material. The frequency and temperature dependences of the loss peaks made it possible to identify which were true relaxations. The effect of water is to decrease the dielectric strength of the composites. However, in both the wet and dry materials, the dielectric strength exhibits a maximum at a loading of about 5 wt% alpha-ZrP. C1 [Bestaoui-Spurr, Naima; Adams, Todd] Lynntech Inc, College Stn, TX 77845 USA. [Edmondson, C. A.; Wintersgill, M. C.; Fontanella, J. J.] USN Acad, Dept Phys, Annapolis, MD 21402 USA. RP Bestaoui-Spurr, N (reprint author), Lynntech Inc, 2501 Earl Rudder Frwy S, College Stn, TX 77845 USA. EM Naima.Bestaoui@Lynntech.com NR 17 TC 1 Z9 1 U1 1 U2 20 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0964-1726 J9 SMART MATER STRUCT JI Smart Mater. Struct. PD SEP PY 2011 VL 20 IS 9 SI SI AR 094001 DI 10.1088/0964-1726/20/9/094001 PG 9 WC Instruments & Instrumentation; Materials Science, Multidisciplinary SC Instruments & Instrumentation; Materials Science GA 818RQ UT WOS:000294773100002 ER PT J AU Ko, S Kim, HC Yang, YC Chong, ST Richards, AL Sames, WJ Klein, TA Kang, JG Chae, JS AF Ko, Sungjin Kim, Heung-Chul Yang, Young-Cheol Chong, Sung-Tae Richards, Allen L. Sames, William J. Klein, Terry A. Kang, Jun-Gu Chae, Joon-Seok TI Detection of Rickettsia felis and Rickettsia typhi and Seasonal Prevalence of Fleas Collected from Small Mammals at Gyeonggi Province in the Republic of Korea SO VECTOR-BORNE AND ZOONOTIC DISEASES LA English DT Article DE Ctenophthalmus congeneroides, Stenoponia sidimi; Flea; Korea; Rickettsia felis; Rickettsia typhi ID SPOTTED-FEVER GROUP; SCRUB TYPHUS; MURINE TYPHUS; SEROLOGICAL SURVEILLANCE; SOUTH-KOREA; CAT FLEAS; BORNE; INFECTION; TICKS; IDENTIFICATION AB Fleas were collected from live-captured small mammals to identify flea-borne pathogens, host associations, and seasonal prevalence of flea species, as part of the 65th Medical Brigade rodent-borne disease surveillance program at 20 military installations and training sites, Gyeonggi Province, Republic of Korea, 2005-2007. A total of 1251 fleas were recovered from 2833 small mammals. Apodemus agrarius, the striped field mouse, accounted for 93.1% (2,637/2,833) of all small mammals captured, followed by Crocidura lasiura (3.1%), Mus musculus (1.3%), Microtus fortis (0.7%), Myodes regulus (0.7%), Micromys minutus (0.5%), Rattus norvegicus (0.4%), Tscherskia triton (0.1%), Apodemus peninsulae (<0.1%), Rattus rattus (<0.1%), and Mogera robusta (<0.1%). A total of 6/11 species of mammals captured were infested with fleas with infestation rates ranging from a high of 26.3% (A. agrarius and M. regulus) to a low of 5.3% (M. fortis). Flea indices among infested mammals were highest for R. norvegicus (2.50), followed by C. lasiura (2.20), A. agrarius (1.71), M. regulus (1.20), M. musculus (1.0), and M. fortis (1.0). The predominant flea species collected were Stenoponia sidimi (56.5%), followed by Ctenophthalmus congeneroides (38.3%) and Rhadinopsylla insolita (3.9%). The minimum field infection rates [ number of positive pools/total number of fleas (600)] for Rickettsia typhi and for Rickettsia felis were 1.7% and 1.0%, respectively. C1 [Ko, Sungjin; Kang, Jun-Gu; Chae, Joon-Seok] Seoul Natl Univ, Coll Vet Med, Dept Vet Internal Med, Res Inst, Seoul 151742, South Korea. [Ko, Sungjin; Kang, Jun-Gu; Chae, Joon-Seok] Seoul Natl Univ, Program Vet Sci BK21, Seoul 151742, South Korea. [Kim, Heung-Chul; Chong, Sung-Tae] 168th Multifunct Med Battal, Med Detachment 5, APO, AP 96205 USA. [Yang, Young-Cheol] Eulji Univ, Dept Environm Hlth, Songnam, South Korea. [Richards, Allen L.] USN, Viral & Rickettsial Dis Dept, Med Res Ctr, Silver Spring, MD USA. [Sames, William J.] Walter Reed Army Med Ctr, OD AFPMB, Washington, DC 20307 USA. [Klein, Terry A.] US Army MEDDAC Korea, Force Hlth Protect & Prevent Med, APO, AP 96205 USA. RP Chae, JS (reprint author), Seoul Natl Univ, Coll Vet Med, Dept Vet Internal Med, Res Inst, Seoul 151742, South Korea. EM jschae@snu.ac.kr RI Valle, Ruben/A-7512-2013 FU Armed Forces Health Surveillance Center; Global Emerging Infections Surveillance and Response System, Silver Spring, MD; Seoul National University, Seoul, Korea FX We thank the commanders and personnel of the 5th and 38th Medical Detachments, 168th Multifunctional Medical Battalion, for their support in conducting small mammal surveillance. We especially thank Dr. Joel Gaydos, Global Emerging Infections Surveillance and Response System, Silver Spring, MD, for his support and constructive criticism. Funding for portions of this work was provided by the Armed Forces Health Surveillance Center, Global Emerging Infections Surveillance and Response System, Silver Spring, MD, the National Center for Military Intelligence, Ft. Detrick, MD, and through the BK21 Program for Veterinary Science, Seoul National University, Seoul, Korea. NR 38 TC 6 Z9 7 U1 1 U2 7 PU MARY ANN LIEBERT INC PI NEW ROCHELLE PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA SN 1530-3667 J9 VECTOR-BORNE ZOONOT JI Vector-Borne Zoonotic Dis. PD SEP PY 2011 VL 11 IS 9 BP 1243 EP 1251 DI 10.1089/vbz.2010.0261 PG 9 WC Public, Environmental & Occupational Health; Infectious Diseases SC Public, Environmental & Occupational Health; Infectious Diseases GA 818QQ UT WOS:000294769900003 PM 21612536 ER PT J AU McGarry, PM AF McGarry, Patrick M. TI Built It and They Didn't Come: The Right Way to Build and Maintain Developer Communities SO BELL LABS TECHNICAL JOURNAL LA English DT Article AB The problem of attracting developers to a community is resulting in growing levels of consternation for many companies. The successes enjoyed by existing developer-based communities producing tangible results do not necessarily show the critical steps required to build such a community from the ground up. By examining the elements of a successful developer community and the archetypes of the necessary participants, I clarify the process by which developers are enticed into, and kept active within, a community. This process is analyzed using qualitative analysis of developer communities and several example communities. This paper challenges community-building methodologies, corporate culture, and the prevailing attitudes surrounding current attempts at developer enticement. Typical approaches are usually seen as insincere or lacking in value, but with appropriate community management and a slight shift in messaging and transparency, true organic growth can be achieved. (C) 2011 Alcatel-Lucent. C1 [McGarry, Patrick M.] Alcatel Lucents Solut Grp, Murray Hill, NJ 07974 USA. [McGarry, Patrick M.] USN, Washington, DC USA. RP McGarry, PM (reprint author), Alcatel Lucents Solut Grp, Murray Hill, NJ 07974 USA. NR 20 TC 0 Z9 0 U1 0 U2 1 PU WILEY PERIODICALS, INC PI MALDEN PA COMMERCE PLACE, 350 MAIN STREET, MALDEN, MA 02148-529 USA SN 1089-7089 J9 BELL LABS TECH J JI Bell Labs Tech. J. PD SEP PY 2011 VL 16 IS 2 SI SI BP 251 EP 262 DI 10.1002/bltj.20514 PG 12 WC Computer Science, Information Systems; Engineering, Electrical & Electronic; Telecommunications SC Computer Science; Engineering; Telecommunications GA 813DW UT WOS:000294348000017 ER PT J AU Laudier, NA Thornton, EB MacMahan, J AF Laudier, Natalie A. Thornton, Edward B. MacMahan, Jamie TI Measured and modeled wave overtopping on a natural beach SO COASTAL ENGINEERING LA English DT Article DE Wave overtopping; Barrier beach; Wave run-up ID LONGSHORE-CURRENT; TIDAL INLETS; BARRED BEACH; SWASH; OVERWASH AB The rate of wave overtopping of a barrier beach is measured and modeled. Unique rate of wave overtopping field data are obtained from the measure of the Carmel River, California, lagoon filling during a time when the lagoon is closed-off with no river inflow. Volume changes are based on measured lagoon height changes applied to a measured hypsometric curve. Wave heights and periods are obtained from directional wave spectra data in 15 m fronting the beach. Beach morphology was measured by GPS walking surveys. Three empirical overtopping models by Van der Meer and Janssen (1995), Hedges and Reis (1998) and Pullen et al. (2007) with differing parameterizations on wave height, period and beach slope and calibrated using extensive laboratory data obtained over plane, impermeable beaches are applied in a quasi-2D manner and compared with the field observations. Three overtopping events are considered when morphology data were available less than 2 weeks prior to the event. The models are tuned to fit the data using a reduction factor to account for beach permeability, berm characteristics, non-normal wave incidence and surface roughness influence. In addition, the run-up model by Stockdon et al. (2006) based on field data is examined and found to underestimate run-up as the calculated values were too small to predict any of the observed overtopping. The three overtopping models performed similarly well with values of 0.72-0.87 for the two narrow-banded wave cases, with an average reduction factor of 0.78. The European model (Pullen et. al., 2007) performed best overall and in particular for the case of the broad-banded, double peaked wave spectrum. Published by Elsevier B.V. C1 [Laudier, Natalie A.; Thornton, Edward B.; MacMahan, Jamie] USN, Postgrad Sch, Dept Oceanog, Monterey, CA 93943 USA. RP Thornton, EB (reprint author), USN, Postgrad Sch, Dept Oceanog, Monterey, CA 93943 USA. EM thornton@nps.edu FU State of California Coastal Ocean Currents Modeling Program (COCMP); Naval Postgraduate School; ONR [Coastal GeoSciencesN0001410WX21049]; NSFOCE [0728324] FX The programming support by Mike Cook and GIS support and surveying help from Arlene Guest and Jon Vevoda are greatly appreciated. Greg James and Larry Hampson at the Monterey Water District provided the lagoon elevation and river discharge data and insight into Carmel River lagoon processes. Bill O'Reilly provided the CDIP data. M. Reis is thanked for suggestions in applying the HR model. We wish to thank the anonymous reviewers for critical comments that substantially improved the paper. Support for this research was provided by the State of California Coastal Ocean Currents Modeling Program (COCMP) and the Naval Postgraduate School. MacMahan was supported by ONR Coastal GeoSciencesN0001410WX21049 and NSFOCE#0728324. NR 34 TC 10 Z9 10 U1 2 U2 11 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0378-3839 J9 COAST ENG JI Coast. Eng. PD SEP PY 2011 VL 58 IS 9 BP 815 EP 825 DI 10.1016/j.coastaleng.2011.04.005 PG 11 WC Engineering, Civil; Engineering, Ocean SC Engineering GA 801ZX UT WOS:000293480200001 ER PT J AU Orzech, MD Reniers, AJHM Thornton, EB MacMahan, JH AF Orzech, Mark D. Reniers, Ad J. H. M. Thornton, Edward B. MacMahan, Jamie H. TI Megacusps on rip channel bathymetry: Observations and modeling SO COASTAL ENGINEERING LA English DT Article DE Megacusps; Rip channels; Sediment transport; Modeling; XBeach ID NATURAL BEACH; ENERGY SATURATION; CURRENT SYSTEMS; CURRENTS; WAVES; FLOW; MORPHODYNAMICS; DISSIPATION; GENERATION; EVOLUTION AB The formation of beach megacusps along the shoreline of southern Monterey Bay, CA, is investigated using time-averaged video and simulated with XBeach, a recently developed coastal sediment transport model. Investigations focus on the hydrodynamic role played by the bay's ever-present rip channels. A review of four years of video and wave data from Sand City, CA, indicates that megacusps most often form shoreward of rip channels under larger waves (significant wave height (H(s)) = 1.5-2.0 m). However, they also occasionally appear shoreward of shoals when waves are smaller (H(s)similar to 1 m) and the mean water level is higher on the beach. After calibration to the Sand City site, XBeach is shown to hindcast measured shoreline change moderately well (skill = 0.41) but to overpredict the erosion of the swash region and beach face. Simulations with small to moderate waves (H(s)=0.5-1.2 m) suggest, similar to field data, that megacusps will form shoreward of either rip channels or shoals, depending on mean daily water level and pre-existing beach shape. A frequency-based analysis of sediment transport forcing is performed, decomposing transport processes to the mean, infragravity, and very-low-frequency (VLF) contributions for two highlighted cases. Results indicate that the mean flow plays the dominant role in both types of megacusp formation, but that VLF oscillations in sediment concentration and advective flow are also significant. Published by Elsevier B.V. C1 [Orzech, Mark D.] USN, Res Lab, Stennis Space Ctr, MS 39529 USA. [Reniers, Ad J. H. M.] Univ Miami, RSMAS, Miami, FL 33149 USA. [Thornton, Edward B.; MacMahan, Jamie H.] USN, Postgrad Sch, Dept Oceanog, Monterey, CA 93943 USA. RP Orzech, MD (reprint author), USN, Res Lab, Code 7322, Stennis Space Ctr, MS 39529 USA. EM mark.orzech.ctr@nrlssc.navy.mil FU state of California's Coastal Ocean Currents Modeling Program (COCMP); ONR [N000140710556, N00014-05-1-0154, N0001407WR20226, N00001408WR20006]; National Science Foundation [OCE 0754426, EAR0952225, OCE 0728324] FX This analysis was funded by the state of California's Coastal Ocean Currents Modeling Program (COCMP). Reniers was supported by ONR contract #N000140710556 and National Science Foundation contracts OCE 0754426 and EAR0952225. Thornton and MacMahan were supported by ONR contracts N00014-05-1-0154, N0001407WR20226, N00001408WR20006, and National Science Foundation contract OCE 0728324. Drs. Tim Stanton, Tom Herbers, and Ken Davidson provided many useful suggestions on the original manuscript, as did two anonymous reviewers. Thanks also to Paul Jessen and Tom Herbers for providing nearshore wave buoy data, to Dr. Rikk Kvitek and Mr. Todd Hallenbeck of California State University, Monterey Bay for providing bathymetry data for southern Monterey Bay, to Jim Stockel for developing both ADCP and video data processing software, and to Rob Wyland, Ron Cowen, and Keith Wyckoff for installing, repairing, and maintaining the video equipment and ADCPs. NR 55 TC 17 Z9 17 U1 0 U2 10 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0378-3839 J9 COAST ENG JI Coast. Eng. PD SEP PY 2011 VL 58 IS 9 BP 890 EP 907 DI 10.1016/j.coastaleng.2011.05.001 PG 18 WC Engineering, Civil; Engineering, Ocean SC Engineering GA 801ZX UT WOS:000293480200007 ER PT J AU Dahlke, JD Terpstra, ER Ramseyer, AM Busch, JM Rieg, T Magann, EF AF Dahlke, Joshua D. Terpstra, Eric R. Ramseyer, Abigail M. Busch, Jeanne M. Rieg, Thomas Magann, Everett F. TI Postpartum insertion of levonorgestrel-intrauterine system at three time periods: a prospective randomized pilot study SO CONTRACEPTION LA English DT Article; Proceedings Paper CT 77th Annual Meeting of the Central-Association-of-Obstetricians-and-Gynecologists CY OCT 27-30, 2010 CL Las Vegas, NV SP Cent Assoc Obstetricians & Gynecologists DE LARC; Levonorgestrel intrauterine system; LNG-IUS; Long-acting; Reversible contraception; Postpartum contraception ID DEVICE INSERTION; CONTRACEPTION; ATTITUDES AB Background: The study was conducted to determine the feasibility of levonorgestrel intrauterine system (LNG-IUS) insertion at three different times postpartum. Study Design: From August 2009 to January 2010, all women desiring LNG-IUS for postpartum contraception were offered enrollment into our study and randomized to three insertion times: immediate (within 10 min of placenta delivery), early (10 min to 48 h postpartum) or interval (>= 6 weeks postpartum). Results: Forty-six women met inclusion criteria and were analyzed. There was no difference in utilization rates at 3 and 6 months between groups (p=.931). Expulsion rates were significantly higher and pain during insertion was significantly lower in the immediate and early groups (p<.001) when compared to the interval group. Conclusion: Insertion of LNG-IUS < 48 h postpartum is feasible in our institution and may be associated with similar utilization at 6 months, increased expulsion rates and decreased pain at insertion when compared to placement after 6 weeks. Published by Elsevier Inc. C1 [Dahlke, Joshua D.; Terpstra, Eric R.; Ramseyer, Abigail M.; Busch, Jeanne M.; Rieg, Thomas] USN, Dept Obstet & Gynecol, Med Ctr, Portsmouth, VA 23708 USA. [Magann, Everett F.] Univ Arkansas Med Sci, Little Rock, AR 72205 USA. RP Dahlke, JD (reprint author), USN, Dept Obstet & Gynecol, Med Ctr, Portsmouth, VA 23708 USA. EM joshua.dahlke@med.navy.mil NR 15 TC 11 Z9 12 U1 0 U2 2 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 0010-7824 J9 CONTRACEPTION JI Contraception PD SEP PY 2011 VL 84 IS 3 BP 244 EP 248 DI 10.1016/j.contraception.2011.01.007 PG 5 WC Obstetrics & Gynecology SC Obstetrics & Gynecology GA 815FB UT WOS:000294510400008 PM 21843688 ER PT J AU Santomauro, M Masterson, J Marguet, C Crain, D AF Santomauro, M. Masterson, J. Marguet, C. Crain, D. TI DEMOGRAPHICS OF MEN RECEIVING VASECTOMIES IN THE US MILITARY 2000-2009 SO FERTILITY AND STERILITY LA English DT Meeting Abstract CT Annual Meeting of the American-Society-for-Reproductive-Medicine CY OCT 15-19, 2011 CL Orlando, FL SP Amer Soc Reprod Med C1 [Santomauro, M.; Masterson, J.; Marguet, C.; Crain, D.] USN, San Diego Med Ctr, San Diego, CA 92152 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 0015-0282 J9 FERTIL STERIL JI Fertil. Steril. PD SEP PY 2011 VL 96 IS 3 SU 1 BP S111 EP S111 PG 1 WC Obstetrics & Gynecology; Reproductive Biology SC Obstetrics & Gynecology; Reproductive Biology GA 814KZ UT WOS:000294452700375 ER PT J AU Crum-Cianflone, NF Krause, D Wessman, D Medina, S Stepenosky, J Brandt, C Boswell, G AF Crum-Cianflone, N. F. Krause, D. Wessman, D. Medina, S. Stepenosky, J. Brandt, C. Boswell, G. TI Fatty liver disease is associated with underlying cardiovascular disease in HIV-infected persons SO HIV MEDICINE LA English DT Article DE coronary artery calcium; coronary artery disease; fatty liver disease; HIV ID CORONARY-ARTERY CALCIUM; ACTIVE ANTIRETROVIRAL THERAPY; INTIMA-MEDIA THICKNESS; COMPUTED-TOMOGRAPHY; MYOCARDIAL-INFARCTION; HEPATIC STEATOSIS; BODY-FAT; SUBCLINICAL ATHEROSCLEROSIS; RISK; CALCIFICATION AB Background Cardiovascular disease is an increasing concern among HIV-infected persons and their providers. We determined if fatty liver disease is a marker for underlying coronary atherosclerosis among HIV-infected persons. Methods We performed a cross-sectional study in HIV-infected adults to evaluate the prevalence of and factors, including fatty liver disease, associated with subclinical coronary atherosclerosis. All participants underwent computed tomography for determination of coronary artery calcium (CAC; positive defined as a score >0) and fatty liver disease (defined as a liver-to-spleen ratio < 1.0). Factors associated with CAC were determined using multivariate logistic regression models. Results We included in the study 223 HIV-infected adults with a median age of 43 years [interquartile range (IQR) 36-50 years]; 96% were male and 49% were Caucasian. The median CD4 count was 586 cells/mu L and 83% were receiving antiretroviral medications. Seventy-five (34%) had a positive CAC score and 29 (13%) subjects had fatty liver disease. Among those with CAC scores of 0, 1-100 and >100, the percentage with concurrent fatty liver disease was 8, 18 and 41%, respectively (P=0.001). In the multivariate model, CAC was associated with increasing age [ odds ratio (OR) 4.3 per 10 years; P<0.01], hypertension (OR 2.6; P<0.01) and fatty liver disease (OR 3.8; P<0.01). Conclusions Coronary atherosclerosis as detected using CAC is prevalent among young HIV-infected persons. The detection of fatty liver disease among HIV-infected adults should prompt consideration of assessment for underlying cardiovascular disease and risk factor reduction. C1 [Crum-Cianflone, N. F.] USN, San Diego Med Ctr, Clin Invest Dept KCA, HIV Clin, San Diego, CA 92134 USA. [Crum-Cianflone, N. F.; Medina, S.; Brandt, C.] Uniformed Serv Univ Hlth Sci, Infect Dis Clin Res Program, Bethesda, MD 20814 USA. [Krause, D.; Wessman, D.] USN, San Diego Med Ctr, Dept Cardiol, San Diego, CA 92134 USA. [Stepenosky, J.; Boswell, G.] USN, San Diego Med Ctr, Dept Radiol, San Diego, CA 92134 USA. RP Crum-Cianflone, NF (reprint author), USN, San Diego Med Ctr, Clin Invest Dept KCA, HIV Clin, 34800 Bob Wilson Dr,Ste 5, San Diego, CA 92134 USA. EM nancy.crum@med.navy.mil FU NIAID NIH HHS [HU0001-05-2-0011, Y01 AI005072]; PHS HHS [HU0001-05-2-0011] NR 46 TC 10 Z9 10 U1 0 U2 2 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1464-2662 J9 HIV MED JI HIV Med. PD SEP PY 2011 VL 12 IS 8 BP 463 EP 471 DI 10.1111/j.1468-1293.2010.00904.x PG 9 WC Infectious Diseases SC Infectious Diseases GA 805SN UT WOS:000293749400002 PM 21251186 ER PT J AU Ma, J Chung, TH Burdick, J AF Ma, Jeremy Chung, Timothy H. Burdick, Joel TI A probabilistic framework for object search with 6-DOF pose estimation SO INTERNATIONAL JOURNAL OF ROBOTICS RESEARCH LA English DT Article DE Range sensing; recognition; sensing and perception computer vision; visual tracking ID VISUAL-ATTENTION AB This article presents a systematic approach to the problem of autonomous 3D object search in indoor environments, using a two-wheeled non-holonomic robot equipped with an actuated stereo-camera head and processing done on a single laptop. A probabilistic grid-based map encodes the likelihood of object existence in each cell and is updated after each sensing action. The updating schema incorporates characteristic parameters modeled after the robot's sensing modalities and allows for sequential updating via Bayesian recursion methods. Two types of sensing modalities are used to update the map: a coarse search method (global search) based on a color histogram approach, and a more refined search method (local search) based on Scale-Invariant Feature Transform (SIFT) feature matching. If the local search correctly locates the desired object, its 6-DOF pose is estimated using stereo applied to each SIFT feature (i.e. 3D SIFT feature), which is then fed as measurements into an Extended Kalman Filter (EKF) for sustained tracking. If the local search fails to locate the desired object in a particular cell, the cell is updated in the probability map and the next peak probability cell is identified and planned to using a separate grid-based costmap populated via obstacle detection from stereo, with planning done using an A* planner. Experimental results obtained from the use of this method on a mobile robot are presented to illustrate and validate the approach, confirming that the search strategy can be carried out with modest computation on a single laptop. C1 [Ma, Jeremy] Jet Prop Lab, Pasadena, CA 91109 USA. [Chung, Timothy H.] Naval Postgrad Sch, Monterey, CA USA. [Burdick, Joel] CALTECH, Pasadena, CA 91109 USA. RP Ma, J (reprint author), Jet Prop Lab, 4800 Oak Grove Dr,M-S 198-235, Pasadena, CA 91109 USA. EM Jeremy.C.Ma@jpl.nasa.gov NR 23 TC 16 Z9 16 U1 0 U2 11 PU SAGE PUBLICATIONS LTD PI LONDON PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND SN 0278-3649 EI 1741-3176 J9 INT J ROBOT RES JI Int. J. Robot. Res. PD SEP PY 2011 VL 30 IS 10 SI SI BP 1209 EP 1228 DI 10.1177/0278364911410090 PG 20 WC Robotics SC Robotics GA 814XT UT WOS:000294491200002 ER PT J AU MacGregor, A Dougherty, A Tang, J Galarneau, M AF MacGregor, Andrew Dougherty, Amber Tang, Janet Galarneau, Michael TI Post-concussive Symptom Reporting Among US Combat Veterans with Mild Traumatic Brain Injury from Operation Iraqi Freedom SO JOURNAL OF HEAD TRAUMA REHABILITATION LA English DT Meeting Abstract C1 [MacGregor, Andrew; Dougherty, Amber; Tang, Janet; Galarneau, Michael] USN, Hlth Res Ctr, San Diego, CA 92152 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0885-9701 J9 J HEAD TRAUMA REHAB JI J. Head Trauma Rehabil. PD SEP-OCT PY 2011 VL 26 IS 5 MA 0032 BP 413 EP 414 PG 2 WC Clinical Neurology; Rehabilitation SC Neurosciences & Neurology; Rehabilitation GA 814VO UT WOS:000294485500038 ER PT J AU Duplessis, CA Tilley, D Bavaro, M Hale, B Holland, SM AF Duplessis, Christopher A. Tilley, Drake Bavaro, Mary Hale, Braden Holland, Steven M. TI Two cases illustrating successful adjunctive interferon-gamma immunotherapy in refractory disseminated coccidioidomycosis SO JOURNAL OF INFECTION LA English DT Article DE Interferon; Coccidioidomycosis; Immunotherapy; IFN-gamma; IL-12 ID MYCOBACTERIAL INFECTION; RECEPTOR AB Protective immunity and host resistance to coccidioidomycosis require a robust cell-mediated immunity with adequate production of Th1 cytokines including interleukin-12, and IFN-gamma and appropriate regulation and coordinated functionality of Th1/Th2 responses and IL-12/IFN-gamma cytokine axes. IFN-gamma augments the anti-fungal activity of effector immune cells against a variety of fungi. Numerous animal models have demonstrated the potential efficacy of adjunctive IFN-gamma in treatment of invasive mycoses. Yet, despite these promising data, a paucity of literature documents efficacious adjunctive IFN-gamma administration in refractory coccidioidomycosis. We present two cases of refractory disease occurring at our institution who responded to adjunctive IFN-gamma. Published by Elsevier Ltd on behalf of The British Infection Association. C1 [Duplessis, Christopher A.; Tilley, Drake; Bavaro, Mary; Hale, Braden] Infect Dis Naval Hosp, Naval Med Ctr San Diego, San Diego, CA 92134 USA. [Holland, Steven M.] NIAID, Lab Clin Infect Dis, NIH, Bethesda, MD 20892 USA. RP Duplessis, CA (reprint author), Infect Dis Naval Hosp, Naval Med Ctr San Diego, 34800 Bob Wilson Dr,Ste 5, San Diego, CA 92134 USA. EM christopher.duplessis@med.navy.mil FU Intramural NIH HHS [Z01 AI000647-16] NR 11 TC 8 Z9 8 U1 0 U2 0 PU W B SAUNDERS CO LTD PI LONDON PA 32 JAMESTOWN RD, LONDON NW1 7BY, ENGLAND SN 0163-4453 J9 J INFECTION JI J. Infect. PD SEP PY 2011 VL 63 IS 3 BP 223 EP 228 DI 10.1016/j.jinf.2011.07.006 PG 6 WC Infectious Diseases SC Infectious Diseases GA 814JX UT WOS:000294448000006 PM 21791226 ER PT J AU Stevens, D Crowder, B Sunshine, D Marchand, K Smilowitz, R Williamson, E Waggoner, M AF Stevens, David Crowder, Brian Sunshine, Doug Marchand, Kirk Smilowitz, Robert Williamson, Eric Waggoner, Mark TI DoD Research and Criteria for the Design of Buildings to Resist Progressive Collapse SO JOURNAL OF STRUCTURAL ENGINEERING-ASCE LA English DT Article DE Progressive collapse; Robustness; Structural integrity; Design criteria AB The collapse of conventional/nonhardened structures was a concern of the U.S. Department of Defense (DoD) for years before the collapse of the World Trade Center (WTC) towers during the terrorist attacks on September 11, 2011 (9-11), owing to the bombings of the Murrah Federal Building in Oklahoma City, the U.S. embassies in Africa, and the U.S. Marine barracks in Lebanon. Since 9-11, motivated by the lack of any meaningful U.S. progressive collapse design requirements, DoD has worked with the civilian community on a number of significant efforts to improve the design of buildings to resist disproportionate collapse. The DoD efforts have included laboratory and field experiments, numerical simulations, and development of design requirements. Synergy and coordination with the civilian community resulted in combined programs with the General Services Administration, guidance and feedback provided by the ASCE Structural Engineering Institute (SEI) Committee on Disproportionate Collapse Standards and Guidance (DCSG) and its members, and adoption of some European civilian approaches to progressive collapse design. A significant result of the DoD effort was the creation of Unified Facilities Criteria (UFC) 4-023-03, Design of Buildings to Resist Progressive Collapse. The approaches employed in UFC 4-023-03 are currently being evaluated and modified for civilian applications by the SEI DCSG committee. The development and underlying approaches used in UFC 4-023-03 are briefly summarized in this paper, as are the previous DoD laboratory and field tests and numerical simulations. DOI: 10.1061/(ASCE)ST.1943-541X.0000432. (C) 2011 American Society of Civil Engineers. C1 [Stevens, David] Protect Engn Consultants, San Antonio, TX 78229 USA. [Crowder, Brian] USN, Facil Engn Command Atlantic, Norfolk, VA 23508 USA. [Sunshine, Doug] Def Threat Reduct Agcy, Canon City, CO 81212 USA. [Marchand, Kirk] Protect Engn Consultants, Austin, TX 78737 USA. [Smilowitz, Robert] Weidlinger Associates Inc, New York, NY 10014 USA. [Williamson, Eric] Univ Texas Austin, Austin, TX 78712 USA. [Waggoner, Mark] Walter P Moore & Associates Inc, Austin, TX 78701 USA. RP Stevens, D (reprint author), Protect Engn Consultants, 4203 Gardendale,Suite C112, San Antonio, TX 78229 USA. EM dstevens@protection-consultants.com; brian.crowder@navy.mil; dougsunshine@bresnan.net; kmarchand@protection-consultants.com; Smilowitz@wai.com; eric.williamson@engr.utexas.edu; mwaggoner@walterpmoore.com NR 31 TC 3 Z9 6 U1 1 U2 12 PU ASCE-AMER SOC CIVIL ENGINEERS PI RESTON PA 1801 ALEXANDER BELL DR, RESTON, VA 20191-4400 USA SN 0733-9445 J9 J STRUCT ENG-ASCE JI J. Struct. Eng.-ASCE PD SEP PY 2011 VL 137 IS 9 SI SI BP 870 EP 880 DI 10.1061/(ASCE)ST.1943-541X.0000432 PG 11 WC Construction & Building Technology; Engineering, Civil SC Construction & Building Technology; Engineering GA 808DH UT WOS:000293955600002 ER PT J AU Shippey, SH Chen, TL Chou, B Knoepp, LR Bowen, CW Honda, VL AF Shippey, Stuart H. Chen, Tiffany L. Chou, Betty Knoepp, Leise R. Bowen, Craig W. Honda, Victoria L. TI Teaching Subcuticular Suturing to Medical Students: Video versus Expert Instructor Feedback SO JOURNAL OF SURGICAL EDUCATION LA English DT Article DE sutures; motor skills; instructional films and videos; medical students; anatomic models ID SURGICAL TECHNICAL SKILL; STRUCTURED ASSESSMENT; RESIDENTS; ACQUISITION; VALIDATION; OSATS AB OBJECTIVE: Given limitations in surgical educational resources, more efficient teaching methods are needed. We sought to evaluate 3 strategies for improving skills in subcuticular suturing practice with an instructional video, practice with expert instructor supervision, and independent practice. DESIGN: Fifty-eight medical students volunteered for this research. Students viewed a video on subcuticular suturing then completed a pretest requiring closure of an incision in a plastic model. Students were randomized among 3 groups: practice with an instructional video (group A), practice with supervision by an expert instructor (group B), and independent practice (group C). After instruction, students completed a posttest, then a retention test 1 week later. Their performances were video recorded and evaluated using a validated scoring instrument composed of global and task-specific subscales. RESULTS: Performances measured using both subscales improved significantly from pretest to post-test only for group B. However, when comparing student performances between pretest and retention posttest, significant improvements on both subscales were seen only in group A. CONCLUSION: These results suggest that practice with an instructional video is an effective method for acquiring skill in subcuticular suturing. (J Surg 68:397-402. (C) 2011 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.) C1 [Shippey, Stuart H.; Chou, Betty; Knoepp, Leise R.; Honda, Victoria L.] Johns Hopkins Bayview Med Ctr, Dept Gynecol & Obstet, Baltimore, MD USA. [Chen, Tiffany L.] Johns Hopkins Univ, Dept Comp Sci, Baltimore, MD 21218 USA. [Bowen, Craig W.] Johns Hopkins Sch Med, Off Med Educ Serv, Baltimore, MD USA. RP Shippey, SH (reprint author), USN, Med Ctr, Dept Gynecol & Obstet, Johns Hopkins Bayview Med Ctr 2197, 620 John Paul Jones Circle, Portsmouth, VA 23708 USA. EM stuart-shippey@med.navy.mil FU APGO/Ortho-McNeil Undergraduate Medical Education Research Award FX Supported by the 2007 APGO/Ortho-McNeil Undergraduate Medical Education Research Award. NR 16 TC 14 Z9 14 U1 1 U2 4 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 1931-7204 J9 J SURG EDUC JI J. Surg. Educ. PD SEP-OCT PY 2011 VL 68 IS 5 BP 397 EP 402 DI 10.1016/j.jsurg.2011.04.006 PG 6 WC Education, Scientific Disciplines; Surgery SC Education & Educational Research; Surgery GA 812SB UT WOS:000294312100013 PM 21821220 ER PT J AU Campbell, J Tirapelle, L Yates, K Clark, R Inaba, K Green, D Plurad, D Lam, L Tang, A Cestero, R Sullivan, M AF Campbell, Julia Tirapelle, Leslie Yates, Kenneth Clark, Richard Inaba, Kenji Green, Donald Plurad, David Lam, Lydia Tang, Andrew Cestero, Ramon Sullivan, Maura TI The Effectiveness of a Cognitive Task Analysis Informed Curriculum to Increase Self-Efficacy and Improve Performance for an Open Cricothyrotomy SO JOURNAL OF SURGICAL EDUCATION LA English DT Article DE cognitive task analysis; self-efficacy; open cricothyrotomy; procedural skills; surgical skills; curriculum development ID SKILLS AB OBJECTIVE: This study explored the effects of a cognitive task analysis (CTA)-informed curriculum to increase surgical skills performance and self-efficacy beliefs for medical students and postgraduate surgical residents learning how to perform an open cricothyrotomy. METHODS: Third-year medical students and postgraduate year 2 and 3 surgery residents were assigned randomly to either the CTA group (n = 12) or the control group (n = 14). The CTA group learned the open cricothyrotomy procedure using the CTA curriculum. The control group received the traditional curriculum. RESULTS: The CTA group outperformed the control group significantly based on a 19-point checklist score (CTA mean score: 17.75, standard deviation [SD] = 2.34; control mean score: 15.14, SD = 2.48; p = 0.006). The CTA group also reported significantly higher self-efficacy scores based on a 140-point self-appraisal inventory (CTA mean score: 126.10, SD = 16.90; control: 110.67, SD = 16.8; p = 0.029). CONCLUSIONS: The CTA curriculum was effective, in increasing the performance and self-efficacy scores for postgraduate surgical residents and medical students performing an open cricothyrotomy. (J Surg 68:403-407. (C) 2011 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.) C1 [Yates, Kenneth; Clark, Richard; Inaba, Kenji; Green, Donald; Plurad, David; Lam, Lydia; Sullivan, Maura] Univ So Calif, Keck Sch Med, Dept Surg, Los Angeles, CA 90089 USA. [Campbell, Julia] Univ So Calif, Ctr Creat Technol, Los Angeles, CA 90089 USA. [Tirapelle, Leslie] Pasadena City Coll, Pasadena, CA USA. [Yates, Kenneth; Clark, Richard; Sullivan, Maura] Univ So Calif, Rossier Sch Educ, Ctr Cognit Technol, Los Angeles, CA 90089 USA. [Tang, Andrew] Univ Arizona, Dept Surg, Tucson, AZ USA. [Cestero, Ramon] USN, Med Res Unit, San Antonio, TX USA. RP Sullivan, M (reprint author), Univ So Calif, Keck Sch Med, Dept Surg, 1510 San Pablo St,Suite 514, Los Angeles, CA 90089 USA. EM mesulliv@usc.edu NR 14 TC 12 Z9 12 U1 1 U2 7 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 1931-7204 J9 J SURG EDUC JI J. Surg. Educ. PD SEP-OCT PY 2011 VL 68 IS 5 BP 403 EP 407 DI 10.1016/j.jsurg.2011.05.007 PG 5 WC Education, Scientific Disciplines; Surgery SC Education & Educational Research; Surgery GA 812SB UT WOS:000294312100014 PM 21821221 ER PT J AU Duda, TF Lin, YT Reeder, DB AF Duda, Timothy F. Lin, Ying-Tsong Reeder, D. Benjamin TI Observationally constrained modeling of sound in curved ocean internal waves: Examination of deep ducting and surface ducting at short range SO JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA LA English DT Article ID SOUTH CHINA SEA; SHALLOW-WATER; INTENSITY FLUCTUATIONS; SOLITONS; PROPAGATION; ELEVATION; SLOPE AB A study of 400 Hz sound focusing and ducting effects in a packet of curved nonlinear internal waves in shallow water is presented. Sound propagation roughly along the crests of the waves is simulated with a three-dimensional parabolic equation computational code, and the results are compared to measured propagation along fixed 3 and 6 km source/receiver paths. The measurements were made on the shelf of the South China Sea northeast of Tung-Sha Island. Construction of the time-varying three-dimensional sound-speed fields used in the modeling simulations was guided by environmental data collected concurrently with the acoustic data. Computed three-dimensional propagation results compare well with field observations. The simulations allow identification of time-dependent sound forward scattering and ducting processes within the curved internal gravity waves. Strong acoustic intensity enhancement was observed during passage of high-amplitude nonlinear waves over the source/receiver paths, and is replicated in the model. The waves were typical of the region (35 m vertical displacement). Two types of ducting are found in the model, which occur asynchronously. One type is three-dimensional modal trapping in deep ducts within the wave crests (shallow thermocline zones). The second type is surface ducting within the wave troughs (deep thermocline zones). (C) 2011 Acoustical Society of America. [DOI: 10.1121/1.3605565] C1 [Duda, Timothy F.; Lin, Ying-Tsong] Woods Hole Oceanog Inst, Dept Appl Ocean Phys & Engn, Woods Hole, MA 02543 USA. [Reeder, D. Benjamin] USN, Dept Oceanog, Postgrad Sch, Monterey, CA 93943 USA. RP Duda, TF (reprint author), Woods Hole Oceanog Inst, Dept Appl Ocean Phys & Engn, Woods Hole, MA 02543 USA. EM tduda@whoi.edu RI Duda, Timothy/A-7282-2010 OI Duda, Timothy/0000-0002-5797-5955 FU Office of Naval Research; Taiwan National Science Council FX Grants from the Office of Naval Research funded this work. Use of the vessels Ocean Researcher I and Ocean Researcher II in this experiment was funded by the Taiwan National Science Council. We thank Professor Chi-Fang Chen for help with the organization of this project. We are grateful to the crew members and technicians for their fine work. The science personnel aboard Ocean Researcher 1 were Dr. Barry Ma (Chief Scientist), Dr. Yung-Shen (Linus) Chiu, Wen-Hua Her, Dr. Ming-Huei Chang, Shang-Hong, Justin Chang, Dr. D. Benjamin Reeder (US Chief Scientist), Chris Miller, Marla Stone, and Keith Wykoff. Professor Ruey-Chang Wei was chief scientist of Ocean Researcher II, which also collected data associated with this study. NR 25 TC 6 Z9 6 U1 0 U2 5 PU ACOUSTICAL SOC AMER AMER INST PHYSICS PI MELVILLE PA STE 1 NO 1, 2 HUNTINGTON QUADRANGLE, MELVILLE, NY 11747-4502 USA SN 0001-4966 J9 J ACOUST SOC AM JI J. Acoust. Soc. Am. PD SEP PY 2011 VL 130 IS 3 BP 1173 EP 1187 DI 10.1121/1.3605565 PG 15 WC Acoustics; Audiology & Speech-Language Pathology SC Acoustics; Audiology & Speech-Language Pathology GA 814XC UT WOS:000294489500011 PM 21895060 ER PT J AU Collins, MD Baer, RN Simpson, HJ AF Collins, Michael D. Baer, Ralph N. Simpson, Harry J. TI Experimental testing of the noise-canceling processor SO JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA LA English DT Article ID SOURCE LOCALIZATION; FIELDS; WAVES; WATER AB Signal-processing techniques for localizing an acoustic source buried in noise are tested in a tank experiment. Noise is generated using a discrete source, a bubble generator, and a sprinkler. The experiment has essential elements of a realistic scenario in matched-field processing, including complex source and noise time series in a waveguide with water, sediment, and multipath propagation. The noise-canceling processor is found to outperform the Bartlett processor and provide the correct source range for signal-to-noise ratios below - 10 dB. The multivalued Bartlett processor is found to outperform the Bartlett processor but not the noise-canceling processor. [DOI: 10.1121/1.3621059] C1 [Collins, Michael D.] USN, Res Lab, Stennis Space Ctr, MS 39529 USA. [Baer, Ralph N.; Simpson, Harry J.] USN, Res Lab, Washington, DC 20375 USA. RP Collins, MD (reprint author), USN, Res Lab, Stennis Space Ctr, MS 39529 USA. EM mike.collins@nrlssc.navy.mil FU Office of Naval Research FX This work was supported by the Office of Naval Research. The merchant ship data were obtained through an international data exchange agreement and the Navy International Programs Office. The authors thank Kyrie K. Jig and Roger R. Volk for assistance in carrying out the experiment and Gregory J. Orris and Michael Nicholas for assistance with the noise-generating devices. NR 12 TC 0 Z9 0 U1 0 U2 1 PU ACOUSTICAL SOC AMER AMER INST PHYSICS PI MELVILLE PA STE 1 NO 1, 2 HUNTINGTON QUADRANGLE, MELVILLE, NY 11747-4502 USA SN 0001-4966 J9 J ACOUST SOC AM JI J. Acoust. Soc. Am. PD SEP PY 2011 VL 130 IS 3 BP 1217 EP 1221 DI 10.1121/1.3621059 PG 5 WC Acoustics; Audiology & Speech-Language Pathology SC Acoustics; Audiology & Speech-Language Pathology GA 814XC UT WOS:000294489500015 PM 21895064 ER PT J AU Krishnamurthy, R Calhoun, R Billings, B Doyle, J AF Krishnamurthy, Raghavendra Calhoun, Ronald Billings, Brian Doyle, James TI Wind turbulence estimates in a valley by coherent Doppler lidar SO METEOROLOGICAL APPLICATIONS LA English DT Article DE COAMPS; dissipation rate; Doppler Lidar; Owens Valley; structure function; TKE ID BOUNDARY-LAYER; RETRIEVAL; VELOCITY; STATISTICS; PROFILES; SYSTEM AB In this paper, the effect of several turbulence parameters during various flow conditions in Owens Valley, educed from coherent Doppler lidar data have been studied. Radial velocity structure functions are processed to estimate the turbulent kinetic energy (TKE) dissipation rate, integral length scale and velocity variance, assuming a theoretical model for isotropic wind fields. Corrections for turbulence measurements have been considered to address the complications due to inherent volumetric averaging of radial velocity over each range gate, noise of the lidar data, and the assumptions required to estimate effects of smaller scales of motion on turbulence quantities. Using data from the Terrain-induced Rotor Experiment (T-REX) in April-May 2006, vertical profiles of wind and turbulence parameters have been retrieved. During T-REX, unusual valley flows were detected by the lidar data, for example on 19 and 27 March 2006, daytime down-valley and night time up-valley flows, respectively, were observed. This paper focuses on understanding various turbulence parameters during these flow events. Turbulence estimates during daytime down-valley conditions were observed to be constant for most of the day, while for night time up-valley circumstances the turbulence increased steadily as the day progressed. Good comparison was observed between lidar and tower measurements, which validate the lidar turbulence retrieval assumptions. Comparison between TKE estimates from lidar and the Coupled Ocean/Atmosphere Mesoscale Prediction System (COAMPS) model is also presented. This analysis will be helpful for improving the current turbulence parameterization schemes in COAMPS. Finally, differences and similarities in turbulence measurements between both the flow regimes are discussed. Copyright (C) 2011 Royal Meteorological Society C1 [Krishnamurthy, Raghavendra; Calhoun, Ronald] Arizona State Univ, Environm Remote Sensing Grp, Tempe, AZ 85287 USA. [Billings, Brian] CNR, Monterey, CA USA. [Doyle, James] USN, Res Lab, Mesoscale Modelling Sect, Monterey, CA USA. RP Krishnamurthy, R (reprint author), Arizona State Univ, Environm Remote Sensing Grp, Main Campus,POB 876106, Tempe, AZ 85287 USA. EM Raghavendr.Krishnamurthy@asu.edu FU ONR Summer Faculty Program; Army Research Office [W911NF0410146, W911NF0710137]; NSF [0522307] FX The authors recognize the support of the ONR Summer Faculty Program, in which one of the authors spent a summer at the Naval Research Laboratory in Monterey, CA. Support was also provided through the Army Research Office, sponsor awards W911NF0410146 and W911NF0710137 (Program Officer: Walter Bach) and the NSF grant 0522307 (Program Officer: Stephan P. Nelson) which made this work possible. ISFF Tower, Sodar and RASS data was provided by NCAR/EOL under sponsorship of the National Science Foundation (see, http://data.eol.ucar.edu/) NR 26 TC 3 Z9 3 U1 0 U2 9 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1350-4827 J9 METEOROL APPL JI Meteorol. Appl. PD SEP PY 2011 VL 18 IS 3 SI SI BP 361 EP 371 DI 10.1002/met.263 PG 11 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA 813WN UT WOS:000294401000009 ER PT J AU Chaturvedi, AR Dolk, DR Drnevich, PL AF Chaturvedi, Alok R. Dolk, Daniel R. Drnevich, Paul L. TI DESIGN PRINCIPLES FOR VIRTUAL WORLDS SO MIS QUARTERLY LA English DT Article DE IS Design theory; virtual world systems; emergent knowledge processes; agent-based simulation; deep structure; platform as a methodology (PaaM); user-developed content (UDC) ID INFORMATION-SYSTEMS; MARKET AB In this research note, we examine the design, development, validation, and use of virtual worlds. Our purpose in doing so is to extend the design science paradigm by developing a set of design principles applicable to the context of virtual environments, particularly those using agent-based simulation as their underlying technology. Our central argument is that virtual worlds comprise a new class of information system, one that combines the structural aspects of traditional modeling and simulation systems in concert with emergent user dynamics of systems supporting emergent knowledge processes. Our approach involves two components. First, we review the characteristics of agent-based virtual worlds (ABVWs) to discern design requirements that may challenge current design theory. From this review, we derive a set of design principles based on deep versus emergent structures where deep structures reflect conventional modeling and simulation system architectures and emergent structures capture the unpredictable user system dynamics inherent in emergent knowledge processes, which increasingly characterize virtual worlds. We illustrate how these design challenges are addressed with an exemplar of a complex mirror world, a large-scale ABVW we developed called Sentient World. Our contribution is the insight of partitioning ABVW architectures into deep and emergent structures that mirror modeling systems and emergent knowledge processes respectively, while developing extended design principles to facilitate their integration. We conclude with a discussion of the implications of our design principles for informing and guiding future research and practice. C1 [Chaturvedi, Alok R.] Purdue Univ, Krannert Sch Management, W Lafayette, IN 47907 USA. [Dolk, Daniel R.] USN, Postgrad Sch, Monterey, CA 93943 USA. [Drnevich, Paul L.] Univ Alabama, Culverhouse Coll Commerce, Tuscaloosa, AL 35487 USA. RP Chaturvedi, AR (reprint author), Purdue Univ, Krannert Sch Management, 403 W State St, W Lafayette, IN 47907 USA. EM alok@purdue.edu; drdolk@nps.edu; dren@ua.edu FU National Science Foundation [0720677] FX This research is partially funded by National Science Foundation grant # 0720677. The authors would like to thank the anonymous reviewers, associate editor, and senior editors for their valuable comments on the manuscripts. The authors would also like to thank Simulex Inc, its founder Alok Chaturvedi, and its developers for making the Sentient World technology and data available to the authors for this research. NR 24 TC 16 Z9 16 U1 4 U2 28 PU SOC INFORM MANAGE-MIS RES CENT PI MINNEAPOLIS PA UNIV MINNESOTA-SCH MANAGEMENT 271 19TH AVE SOUTH, MINNEAPOLIS, MN 55455 USA SN 0276-7783 J9 MIS QUART JI MIS Q. PD SEP PY 2011 VL 35 IS 3 BP 673 EP 684 PG 12 WC Computer Science, Information Systems; Information Science & Library Science; Management SC Computer Science; Information Science & Library Science; Business & Economics GA 809WV UT WOS:000294088300010 ER PT J AU Sullivan, J Yang, JH Day, M Kennedy, Q AF Sullivan, Joseph Yang, Ji Hyun Day, Michael Kennedy, Quinn TI Training Simulation for Helicopter Navigation by Characterizing Visual Scan Patterns SO AVIATION SPACE AND ENVIRONMENTAL MEDICINE LA English DT Article DE expertise; gaze; terrain association; cognition ID DECISION-MAKING; EXPERTISE; STRATEGIES; AGE AB Introduction: Helicopter overland navigation is a cognitively complex task that requires continuous monitoring of system and environment parameters and years of training. This study investigated potential improvements to training simulation by analyzing the influences of flight expertise on visual scan patterns. Methods: There were 12 military officers who varied in flight expertise as defined by total flight hours who participated in overland navigation tasks. Their gaze parameters were tracked via two eye tracking systems while subjects were looking at out-the-window (OTW) and topographic Map views in a fixed based helicopter simulator. Results: Flight performance measures were not predicted by the expertise level of pilots. However, gaze parameters and scan management skills were predicted by the expertise level. For every additional 1000 flight hours, on average, the model predicted the median dwell will decrease 28 ms and the number of view changes will increase 33 times. However, more experienced pilots scanned more OTW than novice pilots, which was contrary to our expectation. A visualization tool (FEST: Flight and Eye Scan visualization Tool) to replay navigation tasks and corresponding gaze data was developed. Qualitative analysis from FEST revealed visual scan patterns of expert pilots not only looking ahead on the map, but also revisiting areas on the map they just flew over to retain confidence in their orientation. Discussion: Based on the analysis provided above, this work demonstrates that neurophysiological markers, such as eye movements, can be used to indicate the aspects of a trainee's cognitive state that are useful for cuing an instructional system. C1 [Sullivan, Joseph; Yang, Ji Hyun; Day, Michael; Kennedy, Quinn] USN, Postgrad Sch, Monterey, CA 93943 USA. RP Yang, JH (reprint author), USN, Postgrad Sch, 700 Dyer Rd,Bldg 245,Rm 265, Monterey, CA 93943 USA. EM jyan1@nps.edu FU Naval Modeling Simulation Office (NMSO); Office of Naval Research (ONR) FX This work is funded by Naval Modeling Simulation Office (NMSO) and Office of Naval Research (ONR). Dr. Sullivan appreciates his Thesis Committee members for providing us insightful advice to the project and paper. Prof. Ron Fricker reviewed the statistical analysis in this paper and we are very thankful. We are grateful to Noah Llyod-Edelman for helping us in calibrating the experimental device. NR 24 TC 8 Z9 8 U1 0 U2 9 PU AEROSPACE MEDICAL ASSOC PI ALEXANDRIA PA 320 S HENRY ST, ALEXANDRIA, VA 22314-3579 USA SN 0095-6562 J9 AVIAT SPACE ENVIR MD JI Aviat. Space Environ. Med. PD SEP PY 2011 VL 82 IS 9 BP 871 EP 878 DI 10.3357/ASEM.2947.2011 PG 8 WC Public, Environmental & Occupational Health; Medicine, General & Internal; Sport Sciences SC Public, Environmental & Occupational Health; General & Internal Medicine; Sport Sciences GA 812EH UT WOS:000294273400003 PM 21888270 ER PT J AU Walker, TO Tummala, M McEachen, J Michael, JB AF Walker, T. Owens, III Tummala, Murali McEachen, John Michael, James Bret TI Flow-Specific Medium Access for Networked Satellite System SO IEEE SYSTEMS JOURNAL LA English DT Article DE Medium access; flow-specific; satellite networks; sensor networks; system of systems ID SENSE MULTIPLE-ACCESS; RADIO CHANNELS; TIME-DIVISION; DELAY; ALOHA AB Prior work in modeling the satellite-based detection and tracking components of the ballistic missile defense system as a large-scale, wireless sensor network relies on a medium access scheme that can accommodate the large propagation delays encountered in these networked satellite systems. While existing satellite-based systems typically employ a form of time division multiple access, recent efforts have begun to explore contention-based approaches. In this work, we quantify the effect of the large propagation delays on both contention-based and contention-free solutions and propose a flow-specific medium access solution that provides improved delay performance by dynamically adapting the networked satellite medium access scheme to changes in both individual flow and link characteristics. A comparison with CSMA and TDMA is provided through simulation results using a version of the traffic-adaptive cooperative wireless sensor medium access control protocol that has been modified to accommodate large propagation delays. C1 [Walker, T. Owens, III] USN Acad, Annapolis, MD 21402 USA. [Tummala, Murali; McEachen, John; Michael, James Bret] USN, Postgrad Sch, Dept Elect & Comp Engn, Monterey, CA 93943 USA. RP Walker, TO (reprint author), USN Acad, Annapolis, MD 21402 USA. EM owalker@usna.edu; mtummala@nps.edu; mceachen@nps.edu; bmichael@nps.edu NR 42 TC 0 Z9 1 U1 0 U2 6 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1932-8184 EI 1937-9234 J9 IEEE SYST J JI IEEE Syst. J. PD SEP PY 2011 VL 5 IS 3 BP 427 EP 434 DI 10.1109/JSYST.2011.2161796 PG 8 WC Computer Science, Information Systems; Engineering, Electrical & Electronic; Operations Research & Management Science; Telecommunications SC Computer Science; Engineering; Operations Research & Management Science; Telecommunications GA 810ZP UT WOS:000294170600012 ER PT J AU Shin, YM Baig, A Barnett, LR Luhmann, NC Pasour, J Larsen, P AF Shin, Young-Min Baig, Anisullah Barnett, Larry R. Luhmann, Neville C., Jr. Pasour, John Larsen, Paul TI Modeling Investigation of an Ultrawideband Terahertz Sheet Beam Traveling-Wave Tube Amplifier Circuit SO IEEE TRANSACTIONS ON ELECTRON DEVICES LA English DT Article DE Backward wave; particle-in-cell (PIC); sever; sheet beam; staggered double grating; terahertz; tube; traveling-wave tube (TWT) AB Extensive numerical analysis has demonstrated that a terahertz (H-band) sheet beam traveling-wave tube (TWT) amplifier circuit, composed of a staggered double grating array waveguide, has very broad bandwidth (similar to 30%) of the fundamental passband (TE mode) with a 7:1 aspect ratio sheet beam without excitation of n = 1 space harmonic backward-wave modes. Particle-in-cell (PIC) simulations utilizing MAGIC3D and CST PS predict that the designed circuit produces similar to 150-300-W output power, corresponding to similar to 3%-5.5% intrinsic electronic efficiency (similar to 35-38-dB saturated gain from 50-mW input driving power), over similar to 25% bandwidth, which is in good agreement with CHRISTINE 1-D code predictions. Simulations, using a perfectly matched layer boundary (similar to-30-dB return loss), show that the circuit stably operates without noticeable oscillation. With a more realistic matching condition (similar to-9.5-dB return loss), it becomes unstable. However, simulations show that the incorporation of an attenuating sever with tapered conductivity suppresses the instability in tube operation. C1 [Shin, Young-Min; Baig, Anisullah; Barnett, Larry R.; Luhmann, Neville C., Jr.] Univ Calif Davis, Dept Appl Sci, Davis, CA 95616 USA. [Pasour, John; Larsen, Paul] USN, Res Lab, Washington, DC 20375 USA. RP Shin, YM (reprint author), Univ Calif Davis, Dept Appl Sci, Davis, CA 95616 USA. EM ymshin@ucdavis.edu; abaig@ucdavis.edu; mntntech@gmail.com; ncluhmann@ucdavis.edu; john.pasour@nrl.navy.mil; paul.larsen@nrl.navy.mil FU DARPA [G8U543366] FX Manuscript received March 15, 2011; revised June 4, 2011; accepted June 7, 2011. Date of current version August 24, 2011. This work was supported by the High Frequency Integrated Vacuum Electronics program of DARPA under Grant G8U543366. The review of this paper was arranged by Editor R. Carter. NR 22 TC 33 Z9 35 U1 1 U2 15 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0018-9383 J9 IEEE T ELECTRON DEV JI IEEE Trans. Electron Devices PD SEP PY 2011 VL 58 IS 9 BP 3213 EP 3218 DI 10.1109/TED.2011.2159842 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA 811BC UT WOS:000294175900055 ER PT J AU Cramer, AM Sudhoff, SD Zivi, EL AF Cramer, Aaron M. Sudhoff, Scott D. Zivi, Edwin L. TI Metric Optimization-Based Design of Systems Subject to Hostile Disruptions SO IEEE TRANSACTIONS ON SYSTEMS MAN AND CYBERNETICS PART A-SYSTEMS AND HUMANS LA English DT Article DE Evolutionary algorithms; performance metrics; simulation; survivability; system engineering ID SHIP DESIGN; RISK AB In many applications, engineering systems are required to operate acceptably well in hostile environments. In the past, survivability engineering has addressed this requirement using heuristic rule-based design approaches followed by analysis to determine if survivability constraints have been satisfied. The treatment of survivability as a constraint rather than an independent design objective hinders the ability of system engineers to trade off survivability with other design objectives, such as cost and performance. Herein, the survivability problem is posed in terms of maximizing expected performance and minimizing the risk of unacceptable performance. Design metrics that allow optimal selection of systems on the basis of these survivability dimensions are presented. The metrics are part of a systematic approach to system engineering in which survivability concerns are quantified and individual systems and entire classes of systems can be compared objectively. These metrics are a necessary step toward an integrated design process wherein tradeoffs between all design objectives can be identified. This methodology is demonstrated on the design of a notional electric warship integrated engineering plant (IEP) that is subject to hostile disruptions posed by antiship missiles. By use of this method, the performance of the IEP is shown to be improved. C1 [Cramer, Aaron M.] Univ Kentucky, Lexington, KY 40506 USA. [Sudhoff, Scott D.] Purdue Univ, W Lafayette, IN 47907 USA. [Zivi, Edwin L.] USN Acad, Annapolis, MD 21402 USA. RP Cramer, AM (reprint author), Univ Kentucky, Lexington, KY 40506 USA. EM cramer@engr.uky.edu; sudhoff@purdue.edu; zivi@usna.edu FU Office of Naval Research [N00014-08-1-0080, N00014-06-1-0314] FX Manuscript received July 22, 2009; revised April 8, 2010; accepted September 4, 2010. Date of publication January 10, 2011; date of current version August 23, 2011. This work was supported by the Office of Naval Research under Contracts N00014-08-1-0080 and N00014-06-1-0314. This paper was recommended by Associate Editor K. W. Hipel. NR 29 TC 6 Z9 6 U1 0 U2 3 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1083-4427 J9 IEEE T SYST MAN CY A JI IEEE Trans. Syst. Man Cybern. Paart A-Syst. Hum. PD SEP PY 2011 VL 41 IS 5 SI SI BP 989 EP 1000 DI 10.1109/TSMCA.2010.2093887 PG 12 WC Computer Science, Cybernetics; Computer Science, Theory & Methods SC Computer Science GA 810OJ UT WOS:000294134300015 ER PT J AU King, MD Ouellette, W Korter, TM AF King, Matthew D. Ouellette, Wayne Korter, Timothy M. TI Noncovalent Interactions in Paired DNA Nucleobases Investigated by Terahertz Spectroscopy and Solid-State Density Functional Theory SO JOURNAL OF PHYSICAL CHEMISTRY A LA English DT Article ID CRYSTAL-STRUCTURE; THEORETICAL-ANALYSIS; 9-METHYLADENINE; SPECTRUM; SERINE; THZ; 1-METHYLTHYMINE; MONOHYDRATE; ASSIGNMENT; DYNAMICS AB Cocrystallized adenine and thymine derivatives, along with the pure monomeric crystals, were investigated by terahertz spectroscopy and solid-state density functional theory (DFT). The methylated nucleobase derivatives crystallize in planar hydrogen-bonded adenine-thymine pairs similar to the manner found in DNA. The spectra obtained for 1-methylthymine, 9-methyladenine, and the 1:1 cocrystal in the range of 10-100 cm(-1) clearly demonstrate that absorptions in this spectral range originate from the uniquely ordered assembly and the intermolecular interactions found in each individual crystal system. The quality of spectral reproduction for the DFT simulations of each system was clearly improved by the inclusion of an empirical correction term for London-type dispersion forces to the calculations. Notably, it was found that these weak dispersion forces in the adenine-thymine cocrystal were necessary to produce a properly converged crystal structure and meaningful simulation of the terahertz vibrational spectrum. C1 [King, Matthew D.; Korter, Timothy M.] Syracuse Univ, Dept Chem, Ctr Sci & Technol 1 014, Syracuse, NY 13244 USA. [Ouellette, Wayne] USN, Ctr Surface Warfare, Indian Head Div, Indian Head, MD 20640 USA. RP Korter, TM (reprint author), Syracuse Univ, Dept Chem, Ctr Sci & Technol 1 014, Syracuse, NY 13244 USA. EM tmkorter@syr.edu FU National Science Foundation [CHE-0847405] FX This research was funded by a grant from the National Science Foundation CAREER Program (CHE-0847405). The authors also thank Syracuse University for continued support. NR 47 TC 25 Z9 26 U1 2 U2 25 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1089-5639 J9 J PHYS CHEM A JI J. Phys. Chem. A PD SEP 1 PY 2011 VL 115 IS 34 SI SI BP 9467 EP 9478 DI 10.1021/jp111878h PG 12 WC Chemistry, Physical; Physics, Atomic, Molecular & Chemical SC Chemistry; Physics GA 810SC UT WOS:000294146400016 PM 21446683 ER PT J AU Guerry, P AF Guerry, Patricia TI N-linked glycosylation in Archaea: two paths to the same glycan SO MOLECULAR MICROBIOLOGY LA English DT Editorial Material ID S-LAYER GLYCOPROTEIN; HALOFERAX-VOLCANII; PROTEIN GLYCOSYLATION; CAMPYLOBACTER-JEJUNI AB N-linked protein glycosylation occurs in all three branches of life, eukaryotes, bacteria and archaea. The simplest system is that of the bacterium, Campylobacter jejuni, in which a heptasaccharide glycan is added to multiple proteins from a single lipid carrier molecule. In the eukaryotic system a conserved tetradecasaccharide modification is first added to target proteins, but is then modified by trimming and addition of other glycans from additional carrier molecules resulting in a diverse array of glycans of distinct functionality. In the halophilic Archaea from the Dead Sea, Haloferax volcanii, the surface array or S-layer protein is glycosylated with a pentasaccharide. This glycan is synthesized from two separate carrier molecules, one that carries a tetrasaccharide and another that carries the terminal mannose, in a process that is analogous to that of eukaryotes. In this issue of Molecular Microbiology the glycosylation of the S-layer of another halophilic Archaea from the Dead Sea, Haloarcula marismortui is characterized (Calo et al., 2011). This S-layer is glycosylated with the same pentasaccharide as that of Hfx. volcanii, but the intact pentasaccharide is synthesized on a single carrier molecule in Har. marismortui in a process that more closely resembles that of the bacterial N-linked system. C1 USN, Enter Dis Dept, Med Res Ctr, Silver Spring, MD 20910 USA. RP Guerry, P (reprint author), USN, Enter Dis Dept, Med Res Ctr, Silver Spring, MD 20910 USA. EM patricia.guerry@med.navy.mil RI Guerry, Patricia/A-8024-2011 NR 12 TC 0 Z9 0 U1 0 U2 2 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 0950-382X J9 MOL MICROBIOL JI Mol. Microbiol. PD SEP PY 2011 VL 81 IS 5 BP 1133 EP 1135 DI 10.1111/j.1365-2958.2011.07782.x PG 3 WC Biochemistry & Molecular Biology; Microbiology SC Biochemistry & Molecular Biology; Microbiology GA 811MC UT WOS:000294214100002 PM 21848800 ER PT J AU Leonard, PW Pollard, CJ Chavez, DE Rice, BM Parrish, DA AF Leonard, Philip W. Pollard, Colin J. Chavez, David E. Rice, Betsy M. Parrish, Damon A. TI 3,6-Bis(4-nitro-1,2,5-oxadiazol-3-yl)-1,4,2,5-dioxadiazene (BNDD): A Powerful Sensitive Explosive SO SYNLETT LA English DT Article DE explosives; furazan; heterocycles; nitrogen; oxidation AB The explosive 3,6-bis(4-nitro-1,2,5-oxadiazol-3-yl)1,4,2,5- dioxadiazene (BNDD) was synthesized by oxidation of the corresponding diamine using hydrogen peroxide in sulfuric acid with sodium tungstate. The product exhibited detonations during sensitivity testing at low insult; the material is shock and friction sensitive. The synthesis of BNDD should only be pursued by knowledgeable researchers exercising extreme caution. C1 [Leonard, Philip W.; Pollard, Colin J.; Chavez, David E.] Los Alamos Natl Lab, Weap Expt Div, Los Alamos, NM 87545 USA. [Rice, Betsy M.] USA, Res Lab, Aberdeen, MD 20783 USA. [Parrish, Damon A.] USN, Res Lab, Struct Matter Lab, Washington, DC 20375 USA. RP Leonard, PW (reprint author), Los Alamos Natl Lab, Weap Expt Div, POB 1663, Los Alamos, NM 87545 USA. EM philipl@lanl.gov FU Joint Munitions Program; U.S. Department of Energy [DE-AC52-06NA25396] FX The authors would like to thank the Los Alamos National Laboratory Analytical team, particularly Annie Giambra for Elemental Analysis, Mary Sandstrom for DSC, and Daniel Preston for impact, friction, and spark sensitivity testing. This work was funded by the Joint Munitions Program. Except where indicated, this information has been authored by employees of the Los Alamos National Security, LLC. (LANS), operator of the Los Alamos National Laboratory under Contract No. DE-AC52-06NA25396 with the U.S. Department of Energy. Released for unlimited audience: LA-UR 11-00570. NR 13 TC 11 Z9 11 U1 0 U2 7 PU GEORG THIEME VERLAG KG PI STUTTGART PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY SN 0936-5214 J9 SYNLETT JI Synlett PD SEP PY 2011 IS 14 BP 2097 EP 2099 DI 10.1055/s-0030-1261169 PG 3 WC Chemistry, Organic SC Chemistry GA 810WZ UT WOS:000294161400031 ER PT J AU Booske, JH Dobbs, RJ Joye, CD Kory, CL Neil, GR Park, GS Park, J Temkin, RJ AF Booske, John H. Dobbs, Richard J. Joye, Colin D. Kory, Carol L. Neil, George R. Park, Gun-Sik Park, Jaehun Temkin, Richard J. TI Vacuum Electronic High Power Terahertz Sources SO IEEE TRANSACTIONS ON TERAHERTZ SCIENCE AND TECHNOLOGY LA English DT Article DE High power terahertz (THz) radiation; terahertz (THz); vacuum electronic devices ID DYNAMIC NUCLEAR-POLARIZATION; COHERENT TRANSITION RADIATION; TRAVELING-WAVE TUBES; HIGH-ASPECT-RATIO; HIGH-FREQUENCY; SUBMILLIMETER WAVELENGTHS; RELATIVISTIC ELECTRONS; GYROTRON OSCILLATOR; PROBE SPECTROSCOPY; LASER AB Recent research and development has been incredibly successful at advancing the capabilities for vacuum electronic device (VED) sources of powerful terahertz (THz) and near-THz coherent radiation, both CW or average and pulsed. Currently, the VED source portfolio covers over 12 orders of magnitude in power (mW-to-GW) and two orders of magnitude in frequency (from < 0.1 to > 10 THz). Further advances are still possible and anticipated. They will be enabled by improved understanding of fundamental beam-wave interactions, electromagnetic mode competition and mode control, along with research and development of new materials, fabrication methods, cathodes, electron beam alignment and focusing, magnet technologies, THz metrology and advanced, broadband output radiation coupling techniques. C1 [Booske, John H.] Univ Wisconsin, Dept Elect & Comp Engn, Madison, WI 53706 USA. [Dobbs, Richard J.] CPI Canada, Georgetown, ON L7G 2J4, Canada. [Joye, Colin D.] USN, Res Lab, Washington, DC 20375 USA. [Kory, Carol L.] Teraphys Inc, Cleveland, OH 44143 USA. [Neil, George R.] Thomas Jefferson Natl Accelerator Facil, Newport News, VA 23606 USA. [Park, Gun-Sik] Seoul Natl Univ, Dept Phys & Astron, Ctr THz Bio Applicat Syst, Seoul 151747, South Korea. [Park, Jaehun] Pohang Univ Sci & Technol, Pohang Accelerator Lab, Pohang 790784, South Korea. [Temkin, Richard J.] MIT, Dept Phys, Cambridge, MA 02139 USA. [Temkin, Richard J.] MIT, Plasma Sci & Fus Ctr, Cambridge, MA 02139 USA. RP Booske, JH (reprint author), Univ Wisconsin, Dept Elect & Comp Engn, 1415 Johnson Dr, Madison, WI 53706 USA. EM booske@engr.wisc.edu; Richard.dobbs@cpii.com; colin.joye@nrl.navy.mil; ckory@teraphysics.com; neil@jlab.org; gunsik@snu.ac.kr; Jae-hunpa@postech.ac.kr; temkin@mit.edu RI Park, Gunsik/A-1415-2014 NR 201 TC 252 Z9 285 U1 12 U2 80 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 2156-342X J9 IEEE T THZ SCI TECHN JI IEEE Trans. Terahertz Sci. Technol. PD SEP PY 2011 VL 1 IS 1 SI SI BP 54 EP 75 DI 10.1109/TTHZ.2011.2151610 PG 22 WC Engineering, Electrical & Electronic; Optics; Physics, Applied SC Engineering; Optics; Physics GA V28TJ UT WOS:000208702800007 ER PT J AU Looney, R AF Looney, Robert TI State vs. Defense: The Battle to Define America's Empire SO MIDDLE EAST JOURNAL LA English DT Book Review C1 [Looney, Robert] Naval Postgrad Sch, Monterey, CA 93943 USA. RP Looney, R (reprint author), Naval Postgrad Sch, Monterey, CA 93943 USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU MIDDLE EAST INST PI WASHINGTON PA 1761 N ST NW, CIRCULATION DEPT, WASHINGTON, DC 20036-2882 USA SN 0026-3141 J9 MIDDLE EAST J JI Middle East J. PD FAL PY 2011 VL 65 IS 4 BP 689 EP 690 PG 2 WC Area Studies SC Area Studies GA V31XJ UT WOS:000208916000023 ER PT J AU Doppmann, GW Najita, JR Carr, JS Graham, JR AF Doppmann, Greg W. Najita, Joan R. Carr, John S. Graham, James R. TI WARM H2O AND OH DISK EMISSION IN V1331 Cyg SO ASTROPHYSICAL JOURNAL LA English DT Article DE circumstellar matter; infrared: stars; stars: formation; stars: individual (V1331 Cyg); stars: pre-main sequence; techniques: radial velocities; techniques: spectroscopic ID MIDINFRARED MOLECULAR-EMISSION; PROTOPLANETARY DISKS; CIRCUMSTELLAR DISKS; ORGANIC-MOLECULES; FORMING REGION; SPITZER SURVEY; INNER DISKS; WATER; STARS; SPECTROSCOPY AB We present high-resolution (R = 24,000) L-band spectra of the young intermediate-mass star V1331 Cyg obtained with NIRSPEC on the Keck II telescope. The spectra show strong, rich emission from water and OH that likely arises from the warm surface region of the circumstellar disk. We explore the use of the new BT2 water line list in fitting the spectra, and we find that it does a much better job than the well-known HITRAN water line list in the observed wavelength range and for the warm temperatures probed by our data. By comparing the observed spectra with synthetic disk emission models, we find that the water and OH emission lines have similar widths (FWHM similar or equal to 18 km s(-1)). If the line widths are set by disk rotation, the OH and water emission lines probe a similar range of disk radii in this source. The water and OH emission are consistent with thermal emission for both components at a temperature similar to 1500 K. The column densities of the emitting water and OH are large, similar to 10(21) cm(-2) and similar to 10(20) cm(-2), respectively. Such a high column density of water is more than adequate to shield the disk midplane from external UV irradiation in the event of complete dust settling out of the disk atmosphere, enabling chemical synthesis to continue in the midplane despite a harsh external UV environment. The large OH-to-water ratio is similar to expectations for UV irradiated disks, although the large OH column density is less easily accounted for. C1 [Doppmann, Greg W.; Najita, Joan R.] Natl Opt Astron Observ, Tucson, AZ 85719 USA. [Carr, John S.] USN, Res Lab, Washington, DC 20375 USA. [Graham, James R.] Univ Calif Berkeley, Dept Astron, Berkeley, CA 92720 USA. [Graham, James R.] Univ Toronto, Dunlap Inst Astron & Astrophys, Toronto, ON M5S 3H4, Canada. RP Doppmann, GW (reprint author), Natl Opt Astron Observ, 950 N Cherry Ave, Tucson, AZ 85719 USA. EM gdoppmann@noao.edu; najita@noao.edu; carr@nrl.navy.mil; jrg@berkeley.edu FU W. M. Keck Foundation; NASA [NNH10A0061]; University of California Lab [09-LR-01-118057-GRAJ]; NSF [AST-0909188]; Naval Research Laboratory FX Data presented herein were obtained at the W. M. Keck Observatory from telescope time allocated to the National Aeronautics and Space Administration through the agency's scientific partnership with the California Institute of Technology and the University of California. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation.; The authors recognize and acknowledge the very significant cultural role and reverence that the summit of Mauna Kea has always had within the indigenous Hawaiian community. We are most fortunate to have the opportunity to conduct observations from this mountain. We thank the Keck Observatory staff who provided support and assistance during our NIRSPEC run. We thank the anonymous referee for a thorough reading of the manuscript, whose comments helped improve the paper. Financial support for G.W.D. was provided in part by the NASA Origins of Solar Systems program NNH10A0061. J.R.G. was supported in part by the University of California Lab Research Program 09-LR-01-118057-GRAJ and NSF AST-0909188. J.R.N. and J.S.C. acknowledge support from the NASA Origins of Solar Systems program. J.S.C. also acknowledges 6.1 funding for basic research in infrared astronomy at the Naval Research Laboratory. NR 38 TC 8 Z9 8 U1 1 U2 4 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X J9 ASTROPHYS J JI Astrophys. J. PD SEP 1 PY 2011 VL 738 IS 1 AR 112 DI 10.1088/0004-637X/738/1/112 PG 18 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 808XO UT WOS:000294015500112 ER PT J AU Grondin, MH Funk, S Lemoine-Goumard, M Van Etten, A Hinton, JA Camilo, F Cognard, I Espinoza, CM Freire, PCC Grove, JE Guillemot, L Johnston, S Kramer, M Lande, J Michelson, P Possenti, A Romani, RW Skilton, JL Theureau, G Weltevrede, P AF Grondin, M. -H. Funk, S. Lemoine-Goumard, M. Van Etten, A. Hinton, J. A. Camilo, F. Cognard, I. Espinoza, C. M. Freire, P. C. C. Grove, J. E. Guillemot, L. Johnston, S. Kramer, M. Lande, J. Michelson, P. Possenti, A. Romani, R. W. Skilton, J. L. Theureau, G. Weltevrede, P. TI DETECTION OF THE PULSAR WIND NEBULA HESS J1825-137 WITH THE FERMI LARGE AREA TELESCOPE SO ASTROPHYSICAL JOURNAL LA English DT Article DE gamma rays: general; ISM: individual objects (G18.0-0.7, HESS J1825-137); pulsars: general; pulsars: individual (PSR B1823-13, PSR J1826-1334) ID SPECTRAL EVOLUTION; SUPERNOVA-REMNANTS; EGRET DATA; MODEL; EMISSION; MISSION; CATALOG; RAYS AB We announce the discovery of 1-100 GeV gamma-ray emission from the archetypal TeV pulsar wind nebula (PWN) HESS J1825-137 using 20 months of survey data from the Fermi-Large Area Telescope (LAT). The gamma-ray emission detected by the LAT is significantly spatially extended, with a best-fit rms extension of sigma = 0 degrees.56 +/- 0 degrees.07 for an assumed Gaussian model. The 1-100 GeV LAT spectrum of this source is well described by a power law with a spectral index of 1.38 +/- 0.12 +/- 0.16 and an integral flux above 1 GeV of (6.50 +/- 0.21 +/- 3.90) x 10(-9) cm(-2) s(-1). The first errors represent the statistical errors on the fit parameters, while the second ones are the systematic uncertainties. Detailed morphological and spectral analyses bring new constraints on the energetics and magnetic field of the PWN system. The spatial extent and hard spectrum of the GeV emission are consistent with the picture of an inverse Compton origin of the GeV-TeV emission in a cooling-limited nebula powered by the pulsar PSR J1826-1334. C1 [Grondin, M. -H.; Lemoine-Goumard, M.] Univ Bordeaux 1, Ctr Etud Nucl Bordeaux Gradignan, CNRS, IN2P3, F-33175 Gradignan, France. [Funk, S.; Van Etten, A.; Lande, J.; Michelson, P.; Romani, R. W.] Stanford Univ, Dept Phys, WW Hansen Expt Phys Lab, Kavli Inst Particle Astrophys & Cosmol, Stanford, CA 94305 USA. [Funk, S.; Van Etten, A.; Lande, J.; Michelson, P.; Romani, R. W.] Stanford Univ, SLAC Natl Accelerator Lab, Stanford, CA 94305 USA. [Hinton, J. A.] Univ Leicester, Dept Phys & Astron, Leicester LE1 7RH, Leics, England. [Camilo, F.] Columbia Univ, Columbia Astrophys Lab, New York, NY 10027 USA. [Cognard, I.; Theureau, G.] CNRS, Lab Phys & Chim Environm, LPCE UMR 6115, F-45071 Orleans 02, France. [Cognard, I.; Theureau, G.] CNRS INSU, Observ Paris, Stn Radioastron Nancay, F-18330 Nancy, France. [Espinoza, C. M.; Kramer, M.; Weltevrede, P.] Univ Manchester, Jodrell Bank Ctr Astrophys, Sch Phys & Astron, Manchester M13 9PL, Lancs, England. [Freire, P. C. C.; Guillemot, L.; Kramer, M.] Max Planck Inst Radioastron, D-53121 Bonn, Germany. [Grove, J. E.] USN, Div Space Sci, Res Lab, Washington, DC 20375 USA. [Johnston, S.] CSIRO, Australia Telescope Natl Facil, Epping, NSW 1710, Australia. [Possenti, A.] INAF, Cagliari Astron Observ, I-09012 Capoterra, CA, Italy. [Skilton, J. L.] Univ Leeds, Sch Phys & Astron, Leeds LS2 9JT, W Yorkshire, England. RP Grondin, MH (reprint author), Univ Bordeaux 1, Ctr Etud Nucl Bordeaux Gradignan, CNRS, IN2P3, F-33175 Gradignan, France. EM grondin@cenbg.in2p3.fr; funk@slac.stanford.edu; lemoine@cenbg.in2p3.fr; ave@stanford.edu RI Funk, Stefan/B-7629-2015 OI Funk, Stefan/0000-0002-2012-0080 FU Instituto Nazionale di Astrofisica in Italy; Centre National d'Etudes Spatiales in France; Science and Technology Facilities Council of the United Kingdom; Commonwealth Government FX The Fermi-LAT Collaboration acknowledges generous ongoing support from a number of agencies and institutes that have supported both the development and the operation of the LAT as well as scientific data analysis. These include the National Aeronautics and Space Administration and the Department of Energy in the United States, the Commissariat a l'Energie Atomique and the Centre National de la Recherche Scientifique/Institut National de Physique Nucleaire et de Physique des Particules in France, the Agenzia Spaziale Italiana, the Istituto Nazionale di Fisica Nucleare, and the Istituto Nazionale di Astrofisica in Italy, the Ministry of Education, Culture, Sports, Science and Technology (MEXT), High Energy Accelerator Research Organization (KEK) and Japan Aerospace Exploration Agency (JAXA) in Japan, and the K. A. Wallenberg Foundation and the Swedish National Space Board in Sweden. Additional support for science analysis during the operations phase from the following agencies is also gratefully acknowledged: the Instituto Nazionale di Astrofisica in Italy and the Centre National d'Etudes Spatiales in France.; The Lovell Telescope is owned and operated by the University of Manchester as part of the Jodrell Bank Centre for Astrophysics with support from the Science and Technology Facilities Council of the United Kingdom.; The Parkes radio telescope is part of the Australia Telescope which is funded by the Commonwealth Government for operation as a National Facility managed by CSIRO. We thank our colleagues for their assistance with the radio timing observations. NR 32 TC 29 Z9 29 U1 1 U2 5 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X EI 1538-4357 J9 ASTROPHYS J JI Astrophys. J. PD SEP 1 PY 2011 VL 738 IS 1 AR 42 DI 10.1088/0004-637X/738/1/42 PG 7 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 808XO UT WOS:000294015500042 ER PT J AU McSwain, MV Ray, PS Ransom, SM Roberts, MSE Dougherty, SM Pooley, GG AF McSwain, M. Virginia Ray, Paul S. Ransom, Scott M. Roberts, Mallory S. E. Dougherty, Sean M. Pooley, Guy G. TI A RADIO PULSAR SEARCH OF THE gamma-RAY BINARIES LS I+61 303 AND LS 5039 SO ASTROPHYSICAL JOURNAL LA English DT Article DE pulsars: general; stars: individual (LS I+61 303, LS 5039) ID X-RAY; MICROQUASAR LS-5039; ORBITAL MODULATION; I +61-DEGREES-303; PSR B1259-63; H-ALPHA; EMISSION; STAR; WIND; I+61-DEGREES-303 AB LS I +61 303 and LS 5039 are exceptionally rare examples of high-mass X-ray binaries with MeV-TeV emission, making them two of only five known "gamma-ray binaries." There has been disagreement within the literature over whether these systems are microquasars, with stellar winds accreting onto a compact object to produce high energy emission and relativistic jets, or whether their emission properties might be better explained by a relativistic pulsar wind colliding with the stellar wind. Here we present an attempt to detect radio pulsars in both systems with the Green Bank Telescope. The upper limits of flux density are between 4.1 and 14.5 mu Jy, and we discuss the null results of the search. Our spherically symmetric model of the wind of LS 5039 demonstrates that any pulsar emission will be strongly absorbed by the dense wind unless there is an evacuated region formed by a relativistic colliding wind shock. LS I +61 303 contains a rapidly rotating Be star whose wind is concentrated near the stellar equator. As long as the pulsar is not eclipsed by the circumstellar disk or viewed through the densest wind regions, detecting pulsed emission may be possible during part of the orbit. C1 [McSwain, M. Virginia] Lehigh Univ, Dept Phys, Bethlehem, PA 18015 USA. [Ray, Paul S.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. [Ransom, Scott M.] Natl Radio Astron Observ, Charlottesville, VA 22903 USA. [Roberts, Mallory S. E.] Eureka Sci Inc, Oakland, CA 94602 USA. [Dougherty, Sean M.] Natl Res Council Canada, Herzberg Inst Astrophys, Domin Radio Astrophys Observ, Penticton, BC V2A 6J9, Canada. [Pooley, Guy G.] Univ Cambridge, Cavendish Lab, Cambridge CB3 0HE, England. RP McSwain, MV (reprint author), Lehigh Univ, Dept Phys, 16 Mem Dr E, Bethlehem, PA 18015 USA. EM mcswain@lehigh.edu; paul.ray@nrl.navy.mil; sransom@nrao.edu; malloryr@gmail.com; sean.dougherty@nrc.ca; guy@mrao.cam.ac.uk FU NASA DPR [NNX08AV70G, NNG08E1671, NNX09AT67G]; Lehigh University FX We are grateful to Carl Bignell and the staff at NRAO for their help in scheduling and performing these observations. We also thank Guillaume Dubus and Anna Szostek for helpful discussions about the stellar winds and possible contact discontinuities in these systems. The National Radio Astronomy Observatory is a facility of the National Science Foundation operated under cooperative agreement by Associated Universities, Inc. This work is supported by NASA DPR numbers NNX08AV70G, NNG08E1671, and NNX09AT67G. M.V.M. is grateful for an institutional grant from Lehigh University. NR 67 TC 17 Z9 17 U1 0 U2 4 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X J9 ASTROPHYS J JI Astrophys. J. PD SEP 1 PY 2011 VL 738 IS 1 AR 105 DI 10.1088/0004-637X/738/1/105 PG 6 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 808XO UT WOS:000294015500105 ER PT J AU Tran, PG Mungan, CE AF Phuc G Tran Mungan, Carl E. TI Hanging angles of two electrostatically repelling pith balls of different masses SO EUROPEAN JOURNAL OF PHYSICS LA English DT Editorial Material AB An analytic solution can be derived for the angles of two mutually repelling charged pith balls of unequal mass hanging from strings from a common point of attachment. Just as in the equal-mass case, a cubic equation is found for the square of the sine of either angle, and an approximation can be used to avoid Cardano's formula for small angles. These results extend a standard problem treated in introductory undergraduate courses in electricity and magnetism. C1 [Phuc G Tran] John Tyler Community Coll, Dept Nat Sci, Chester, VA 23831 USA. [Mungan, Carl E.] USN Acad, Dept Phys, Annapolis, MD 21402 USA. RP Tran, PG (reprint author), John Tyler Community Coll, Dept Nat Sci, Chester, VA 23831 USA. EM mungan@usna.edu NR 2 TC 1 Z9 1 U1 0 U2 1 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0143-0807 J9 EUR J PHYS JI Eur. J. Phys. PD SEP PY 2011 VL 32 IS 5 BP L25 EP L27 DI 10.1088/0143-0807/32/5/L02 PG 3 WC Education, Scientific Disciplines; Physics, Multidisciplinary SC Education & Educational Research; Physics GA 808YS UT WOS:000294018500002 ER PT J AU Kweon, O Kim, SJ Holland, RD Chen, HY Kim, DW Gao, Y Yu, LR Baek, S Baek, DH Ahn, H Cerniglia, CE AF Kweon, Ohgew Kim, Seong-Jae Holland, Ricky D. Chen, Hongyan Kim, Dae-Wi Gao, Yuan Yu, Li-Rong Baek, Songjoon Baek, Dong-Heon Ahn, Hongsik Cerniglia, Carl E. TI Polycyclic Aromatic Hydrocarbon Metabolic Network in Mycobacterium vanbaalenii PYR-1 SO JOURNAL OF BACTERIOLOGY LA English DT Article ID SP STRAIN PYR-1; RING-HYDROXYLATING OXYGENASES; DEGRADING MYCOBACTERIUM; SYSTEMS-BIOLOGY; MOLECULAR CHARACTERIZATION; DEGRADATION PATHWAY; PYRENE DEGRADATION; FUNCTIONAL MODULES; GROWTH SUBSTRATE; ORGANIZATION AB This study investigated a metabolic network (MN) from Mycobacterium vanbaalenii PYR-1 for polycyclic aromatic hydrocarbons (PAHs) from the perspective of structure, behavior, and evolution, in which multilayer omics data are integrated. Initially, we utilized a high-throughput proteomic analysis to assess the protein expression response of M. vanbaalenii PYR-1 to seven different aromatic compounds. A total of 3,431 proteins (57.38% of the genome-predicted proteins) were identified, which included 160 proteins that seemed to be involved in the degradation of aromatic hydrocarbons. Based on the proteomic data and the previous metabolic, biochemical, physiological, and genomic information, we reconstructed an experiment-based system-level PAH-MN. The structure of PAH-MN, with 183 metabolic compounds and 224 chemical reactions, has a typical scale-free nature. The behavior and evolution of the PAH-MN reveals a hierarchical modularity with funnel effects in structure/function and intimate association with evolutionary modules of the functional modules, which are the ring cleavage process (RCP), side chain process (SCP), and central aromatic process (CAP). The 189 commonly upregulated proteins in all aromatic hydrocarbon treatments provide insights into the global adaptation to facilitate the PAH metabolism. Taken together, the findings of our study provide the hierarchical viewpoint from genes/proteins/metabolites to the network via functional modules of the PAH-MN equipped with the engineering-driven approaches of modularization and rationalization, which may expand our understanding of the metabolic potential of M. vanbaalenii PYR-1 for bioremediation applications. C1 [Kweon, Ohgew; Kim, Seong-Jae; Kim, Dae-Wi; Cerniglia, Carl E.] Natl Ctr Toxicol Res FDA, Div Microbiol, Jefferson, AR 72079 USA. [Kweon, Ohgew; Kim, Seong-Jae; Kim, Dae-Wi; Cerniglia, Carl E.] US FDA, Div Microbiol, Natl Ctr Toxicol Res, Jefferson, AR 72079 USA. [Holland, Ricky D.; Gao, Yuan; Yu, Li-Rong] US FDA, Div Syst Biol, Natl Ctr Toxicol Res, Jefferson, AR 72079 USA. [Chen, Hongyan; Ahn, Hongsik] SUNY Stony Brook, Dept Appl Math & Stat, Stony Brook, NY 11794 USA. [Baek, Songjoon] USN Hosp, NCI, Lab Receptor Biol & Gene Express, NIH, Bethesda, MD 20814 USA. [Baek, Dong-Heon] Dankook Univ, Dept Oral Microbiol & Immunol, Sch Dent, Cheonan 330714, South Korea. RP Cerniglia, CE (reprint author), US FDA, Div Microbiol, Natl Ctr Toxicol Res, 3900 NCTR Rd, Jefferson, AR 72079 USA. EM carl.cerniglia@fda.hhs.gov FU U.S. Department of Energy; U.S. Food and Drug Administration FX This work was supported in part by an appointment to the Postgraduate Research Fellowship Program (D.K.) at the National Center for Toxicological Research, administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the U.S. Department of Energy and the U.S. Food and Drug Administration. The views presented in this article do not necessarily reflect those of the U.S. FDA. NR 49 TC 32 Z9 34 U1 4 U2 49 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA SN 0021-9193 J9 J BACTERIOL JI J. Bacteriol. PD SEP PY 2011 VL 193 IS 17 BP 4326 EP 4337 DI 10.1128/JB.00215-11 PG 12 WC Microbiology SC Microbiology GA 806EE UT WOS:000293788300003 PM 21725022 ER PT J AU Hamdan, LJ Gillevet, PM Pohlman, JW Sikaroodi, M Greinert, J Coffin, RB AF Hamdan, Leila J. Gillevet, Patrick M. Pohlman, John W. Sikaroodi, Masoumeh Greinert, Jens Coffin, Richard B. TI Diversity and biogeochemical structuring of bacterial communities across the Porangahau ridge accretionary prism, New Zealand SO FEMS MICROBIOLOGY ECOLOGY LA English DT Article DE bacteria; AOM; marine sediment; methane; sulfate; 454-pyrosequencing ID GULF-OF-MEXICO; ANAEROBIC METHANE OXIDATION; DISSOLVED ORGANIC-CARBON; COLD SEEP SEDIMENTS; GAS HYDRATE; DEEP-SEA; HIKURANGI MARGIN; MICROBIAL COMMUNITIES; SULFATE REDUCTION; MARINE-SEDIMENTS AB Sediments from the Porangahau ridge, located off the northeastern coast of New Zealand, were studied to describe bacterial community structure in conjunction with differing biogeochemical regimes across the ridge. Low diversity was observed in sediments from an eroded basin seaward of the ridge and the community was dominated by uncultured members of the Burkholderiales. Chloroflexi/GNS and Deltaproteobacteria were abundant in sediments from a methane seep located landward of the ridge. Gas-charged and organic-rich sediments further landward had the highest overall diversity. Surface sediments, with the exception of those from the basin, were dominated by Rhodobacterales sequences associated with organic matter deposition. Taxa related to the Desulfosarcina/Desulfococcus and the JS1 candidates were highly abundant at the sulfate-methane transition zone (SMTZ) at three sites. To determine how community structure was influenced by terrestrial, pelagic and in situ substrates, sequence data were statistically analyzed against geochemical data (e.g. sulfate, chloride, nitrogen, phosphorous, methane, bulk inorganic and organic carbon pools) using the Biota-Environmental matching procedure. Landward of the ridge, sulfate was among the most significant structuring factors. Seaward of the ridge, silica and ammonium were important structuring factors. Regardless of the transect location, methane was the principal structuring factor on SMTZ communities. C1 [Hamdan, Leila J.; Coffin, Richard B.] USN, Res Lab, Marine Biogeochem Sect, Washington, DC USA. [Gillevet, Patrick M.; Sikaroodi, Masoumeh] George Mason Univ, Dept Environm Sci & Policy, Microbiome Anal Ctr, Manassas, VA USA. [Pohlman, John W.] US Geol Survey, Woods Hole Coastal & Marine Sci Ctr, Woods Hole, MA 02543 USA. [Greinert, Jens] Royal Netherlands Inst Sea Res NIOZ, Dept Marine Geol, Den Burg, Texel, Netherlands. RP Hamdan, LJ (reprint author), USN, Res Lab, Marine Biogeochem Sect, Code 6114,Overlook Ave SW, Washington, DC USA. EM leila.hamdan@nrl.navy.mil RI Hamdan, Leila/A-4535-2009; OI Hamdan, Leila/0000-0001-7331-0729; Greinert, Jens/0000-0001-6186-8573 FU Naval Research Laboratory; Office of Naval Research FX This work was supported by the Naval Research Laboratory Chemistry Division Young Investigator Program and the Office of Naval Research platform support program. We thank the captain and crew of the R/V Tangaroa for field assistance, Roswell Downer and Layton Bryant for sample recovery, Rebecca Plummer and Dillon Gustafson for laboratory assistance and Ingo Pecher and Suzannah Toulmin for helpful discussions. We thank Co-Chief Scientists Ingo Pecher and Stewart Henrys and the CHARMNZ science party for their support of this study. NR 73 TC 16 Z9 16 U1 3 U2 30 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 0168-6496 J9 FEMS MICROBIOL ECOL JI FEMS Microbiol. Ecol. PD SEP PY 2011 VL 77 IS 3 BP 518 EP 532 DI 10.1111/j.1574-6941.2011.01133.x PG 15 WC Microbiology SC Microbiology GA 804WJ UT WOS:000293684700005 PM 21595727 ER PT J AU Hartman, JR Lin, S AF Hartman, JudithAnn R. Lin, Shirley TI Analysis of Student Performance on Multiple-Choice Questions in General Chemistry SO JOURNAL OF CHEMICAL EDUCATION LA English DT Article DE First-Year Undergraduate/General; Chemical Education Research; Problem Solving/Decision Making; Testing/Assessment; Learning Theories; Nonmajor Courses ID LABORATORY PRACTICAL EXAMINATIONS; WRITING SKILLS; EXAM QUESTIONS; M-DEMAND; HOMEWORK; PRESENTATIONS; DIFFERENCE; FEEDBACK; LOCS AB The percentage of students choosing the correct answer (PSCA) on 17 multiple-choice algorithmic questions taken from general chemistry exams is analyzed. PSCAs for these questions varied from 47 to 93%, and a decrease of 4.5% in PSCA was observed with each additional step in the algorithm required for solving the problem (R(2) = 0.80). Variants of a subset of these questions were also examined and reveal the effect of making changes to a particular algorithmic question on the ability of students to choose the correct answer. C1 [Hartman, JudithAnn R.; Lin, Shirley] USN Acad, Dept Chem, Annapolis, MD 21402 USA. RP Hartman, JR (reprint author), USN Acad, Dept Chem, Annapolis, MD 21402 USA. EM hartman@usna.edu; lin@usna.edu NR 35 TC 5 Z9 5 U1 1 U2 29 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0021-9584 J9 J CHEM EDUC JI J. Chem. Educ. PD SEP PY 2011 VL 88 IS 9 BP 1223 EP 1230 DI 10.1021/ed100133v PG 8 WC Chemistry, Multidisciplinary; Education, Scientific Disciplines SC Chemistry; Education & Educational Research GA 806MU UT WOS:000293813100009 ER PT J AU Mohr, SB Gorham, ED Alcaraz, JE Kane, CJ Macera, CA Parsons, JK Wingard, DL Garland, CF AF Mohr, Sharif B. Gorham, Edward D. Alcaraz, John E. Kane, Christopher J. Macera, Caroline A. Parsons, J. Kellogg Wingard, Deborah L. Garland, Cedric F. TI Serum 25-Hydroxyvitamin D and Prevention of Breast Cancer: Pooled Analysis SO ANTICANCER RESEARCH LA English DT Article DE Vitamin D; 25-hydroxyvitamin D; breast neoplasms; case control studies; epidemiology; meta-analysis; prevention ID VITAMIN-D SUPPLEMENTATION; DOSE-RESPONSE; FOREST PLOTS; RISK; CALCIUM; MORTALITY; CELLS; POPULATION; SAFETY; COLON AB Background: Low serum levels of 25-hydroxyvitamin D [25(OH)D] have been associated with a high risk of breast cancer. Since publication of the most current meta-analysis of 25(OH)D and breast cancer risk, two new nested case-control studies have emerged. Materials and Methods: A PubMed search for all case-control studies on risk of breast cancer by 25(OH)D concentration identified I 1 eligible studies. Data from all 11 studies were combined in order to calculate the pooled odds ratio of the highest vs. lowest quantile of 25(OH)D across all studies. Results: The overall Peto odds ratio summarizing the estimated risk in the highest compared to the lowest quantile across all 11 studies was 0.61 (95% confidence interval 0.47, 0.80). Conclusion: This study supports the hypothesis that higher serum 25(OH)D levels reduce the risk of breast cancer. According to the review of observational studies, a serum 25(OH)D level of 47 ng/ml was associated with a 50% lower risk of breast cancer. C1 [Mohr, Sharif B.; Gorham, Edward D.; Wingard, Deborah L.; Garland, Cedric F.] Univ Calif San Diego, Dept Family & Prevent Med, Div Epidemiol, Sch Med, La Jolla, CA 92093 USA. [Kane, Christopher J.; Parsons, J. Kellogg] Univ Calif San Diego, Dept Surg, Sch Med, La Jolla, CA 92093 USA. [Gorham, Edward D.; Macera, Caroline A.; Garland, Cedric F.] USN, Hlth Res Ctr, San Diego, CA 92152 USA. [Alcaraz, John E.; Macera, Caroline A.] San Diego State Univ, Grad Sch Publ Hlth, Dept Epidemiol & Biostat, San Diego, CA 92182 USA. RP Mohr, SB (reprint author), Univ Calif San Diego, Dept Family & Prevent Med, Div Epidemiol, Sch Med, 9500 Gilman Dr,0620, La Jolla, CA 92093 USA. EM sbmohr75@gmail.com FU Department of the Navy, Bureau of Medicine and Surgery [60126] FX This research was supported by a Congressional allocation to the Penn State Cancer Institute of the Milton S. Hershey Medical Center, Hershey, PA, through the Department of the Navy, Bureau of Medicine and Surgery, under Work Unit No. 60126. The views expressed in this report are those of the Authors and do not represent an official position of the Department of the Navy, Department of Defense, or the U.S. Government. NR 66 TC 33 Z9 33 U1 0 U2 2 PU INT INST ANTICANCER RESEARCH PI ATHENS PA EDITORIAL OFFICE 1ST KM KAPANDRITIOU-KALAMOU RD KAPANDRITI, PO BOX 22, ATHENS 19014, GREECE SN 0250-7005 EI 1791-7530 J9 ANTICANCER RES JI Anticancer Res. PD SEP PY 2011 VL 31 IS 9 BP 2939 EP 2948 PG 10 WC Oncology SC Oncology GA 800KG UT WOS:000293357700035 PM 21868542 ER PT J AU Scandrett, CL Boisvert, JE Howarth, TR AF Scandrett, Clyde L. Boisvert, Jeffrey E. Howarth, Thomas R. TI Broadband optimization of a pentamode-layered spherical acoustic waveguide SO WAVE MOTION LA English DT Article DE Acoustic cloaking; Pentamodes; Scattering ID CLOAKING; ELASTICITY AB Transformational acoustics offers the theoretical possibility of cloaking obstacles within fluids, provided metamaterials having continuously varying bulk moduli and densities can be found or constructed. Realistically, materials with the proper, continuously varying anisotropies do not presently exist. Discretely layered cloaks having constant material parameters within each layer are a viable alternative, but due to their discrete nature, may become ineffective outside of narrow frequency ranges. Because of such limitations, there is interest in finding discretely layered systems that can be effective in as wide as possible bandwidth without the need for unrealizable material properties within each layer. The present work introduces a novel methodology for finding optimal material parameters for use in such layered cloaks. In principle, the technique could be applied to any acoustic or electromagnetic scattering problem, but for purposes of demonstration, this paper considers a fluid-loaded acoustically hard sphere with a cloak that comprised layered pentamodes, whose material properties are constrained to lie within reasonable ranges relative to the density and bulk modulus of water. Published by Elsevier B.V. C1 [Scandrett, Clyde L.] USN, Postgrad Sch, Dept Appl Math, Monterey, CA 93943 USA. [Boisvert, Jeffrey E.; Howarth, Thomas R.] NAVSEA Newport, Newport, RI 02841 USA. RP Scandrett, CL (reprint author), USN, Postgrad Sch, Dept Appl Math, Monterey, CA 93943 USA. EM clscandr@nps.edu NR 13 TC 6 Z9 7 U1 1 U2 15 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0165-2125 J9 WAVE MOTION JI Wave Motion PD SEP PY 2011 VL 48 IS 6 SI SI BP 505 EP 514 DI 10.1016/j.wavemoti.2011.02.007 PG 10 WC Acoustics; Mechanics; Physics, Multidisciplinary SC Acoustics; Mechanics; Physics GA 803UB UT WOS:000293606000006 ER PT J AU Seely, JF Szabo, CI Feldman, U Chen, H Hudson, LT Henins, A AF Seely, J. F. Szabo, C. I. Feldman, Uri Chen, Hui Hudson, L. T. Henins, A. TI Gamma ray spectra from targets irradiated by picosecond lasers SO HIGH ENERGY DENSITY PHYSICS LA English DT Article DE Gamma ray; Positron; Picosecond laser AB Photon spectra in the energy range 60 keV to 1 MeV were recorded from targets irradiated by the LLNL Titan and LLE EP picosecond lasers. The radiation consisted of K-shell radiation, bremsstrahlung radiation from MeV electrons, and preliminary evidence for 511 keV positron annihilation radiation. The spectra were recorded by two instruments, an energy-dispersive CCD detector with a CsI phosphor coating that operated in the single-hit per pixel mode and was absolutely calibrated using a Cs-137 662 keV source, and a wavelength-dispersive Cauchois type spectrometer employing a curved Ge(220) transmission crystal that operated in the first and second diffraction orders with high spectral resolution. The calibrated photon energy distributions from Au, Eu, and Al targets are compared to the energetic electron distributions emerging from the targets. Published by Elsevier B. V. C1 [Seely, J. F.] USN, Res Lab, Washington, DC 20375 USA. [Szabo, C. I.; Feldman, Uri] Artep Inc, Ellicott City, MD 21042 USA. [Chen, Hui] Lawrence Livermore Natl Lab, Livermore, CA 94550 USA. [Hudson, L. T.; Henins, A.] NIST, Gaithersburg, MD 20899 USA. RP Seely, JF (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM john.seely@nrl.navy.mil FU U.S. DOE by LLNL [DE-AC52-07NA27344]; Office of Naval Research FX We thank Drs. J. Schumer, C. Boyer, and N. Pereira of the NRL Plasma Physics Division for contributions to the CCD detector. The work at NRL was supported by the Office of Naval Research. H. C. was funded under the auspices of the U.S. DOE by LLNL under DE-AC52-07NA27344. Certain commercial equipment, instruments, or materials are identified in this paper in order to specify the experimental procedure adequately. Such identification is not intended to imply recommendation or endorsement by the U.S. government, nor is it intended to imply that the materials or equipment identified are necessarily the best available for the purpose. NR 8 TC 2 Z9 2 U1 0 U2 7 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 1574-1818 J9 HIGH ENERG DENS PHYS JI High Energy Density Phys. PD SEP PY 2011 VL 7 IS 3 BP 150 EP 154 DI 10.1016/j.hedp.2011.04.002 PG 5 WC Physics, Fluids & Plasmas SC Physics GA 791WU UT WOS:000292700200007 ER PT J AU Landrum, ML Roediger, MP Fieberg, AM Weintrob, AC Okulicz, JF Crum-Cianflone, NF Ganesan, A Lalani, T Macalino, GE Chun, HM AF Landrum, Michael L. Roediger, Mollie P. Fieberg, Ann M. Weintrob, Amy C. Okulicz, Jason F. Crum-Cianflone, Nancy F. Ganesan, Anuradha Lalani, Tahaniyat Macalino, Grace E. Chun, Helen M. TI Development of Chronic Hepatitis B Virus Infection in Hepatitis B Surface Antigen Negative HIV/HBV Co-Infected Adults: A Rare Opportunistic Illness SO JOURNAL OF MEDICAL VIROLOGY LA English DT Article DE hepatitis B virus; chronic hepatitis B virus; human immunodeficiency virus; CD4 cell count; opportunistic illness ID ACTIVE ANTIRETROVIRAL THERAPY; HUMAN-IMMUNODEFICIENCY-VIRUS; HIV; SEROCONVERSION; INDIVIDUALS; EVOLUTION; COHORT; HBV AB Changes in serologic status in human immunodeficiency virus (HIV)/hepatitis B virus (HBV) co-infected individuals with either isolated anti-HBc or resolved HBV infection have been reported, but the frequency of clinically meaningful long-term serologic changes is not well-defined. This study therefore, examined longitudinal serologic status for hepatitis B surface antigen (HBsAg)-negative HIV/HBV co-infected participants in a large cohort. Among 5,222 cohort participants, 347 (7%) were initially isolated anti-HBc positive, and 1,073 (21%) had resolved HBV infection (concurrently reactive for anti-HBc and anti-HBs). Thirty-three (10%) of the 347 participants with isolated anti-HBc were later positive for HBsAg at least once, compared with 3 (0.3%) of those with resolved HBV (P < 0.001). A total of 14 participants became persistently positive for HBsAg and were thus classified as having late-onset chronic HBV infection at a median of 3.7 years after initial HBV diagnosis. For those initially with HBsAg-negative HIV/HBV co-infection, the rate of late-onset chronic HBV infection was 1.39/1,000 person-years. Those with late-onset chronic HBV infection experienced significant decreases in CD4 cell counts (P = 0.002) with a mean of 132 cells/mu l at the time of late-onset chronic HBV infection, but no factor distinguished those who were positive for HBsAg only once from those that developed late-onset chronic HBV infection. Over a median of 2.9 years following late-onset chronic HBV infection, 3 of 14 subsequently lost HBsAg. The occurrence of late-onset chronic HBV infection in HBsAg negative HIV/HBV co-infected adults appears to be one important, albeit rare, clinical event seen almost exclusively in those with isolated anti-HBc and low CD4 cell count. J. Med. Virol. 83: 1537-1543, 2011. (C) 2011 Wiley-Liss, Inc. C1 [Landrum, Michael L.] San Antonio Mil Med Ctr, Infect Dis Serv, MCHE MDI, Ft Sam Houston, TX 78234 USA. [Landrum, Michael L.; Roediger, Mollie P.; Fieberg, Ann M.; Weintrob, Amy C.; Crum-Cianflone, Nancy F.; Ganesan, Anuradha; Lalani, Tahaniyat; Macalino, Grace E.] Uniformed Serv Univ Hlth Sci, Infect Dis Clin Res Program, Bethesda, MD 20814 USA. [Roediger, Mollie P.; Fieberg, Ann M.] Univ Minnesota, Div Biostat, Minneapolis, MN USA. [Weintrob, Amy C.] Walter Reed Army Med Ctr, Infect Dis Serv, Washington, DC 20307 USA. [Crum-Cianflone, Nancy F.] USN, Med Ctr, Infect Dis Clin, San Diego, CA 92152 USA. [Ganesan, Anuradha] Natl Naval Med Ctr, Div Infect Dis, Bethesda, MD USA. [Lalani, Tahaniyat] USN, Med Ctr, Div Infect Dis, Portsmouth, VA USA. [Chun, Helen M.] USN, Hlth Res Ctr, Dept Def HIV AIDS Prevent Program, San Diego, CA 92152 USA. RP Landrum, ML (reprint author), San Antonio Mil Med Ctr, Infect Dis Serv, MCHE MDI, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA. EM mlandrum@idcrp.org FU Infectious Disease Clinical Research Program (IDCRP) [IDCRP-000-27]; Uniformed Services University of the Health Sciences (Department of Defense (DoD)); National Institute of Allergy and Infectious Diseases; National Institutes of Health (NIH) [Y1-AI-5072] FX Grant sponsor: Infectious Disease Clinical Research Program (IDCRP, www.idcrp.org); Grant number: IDCRP-000-27; Grant sponsor: Uniformed Services University of the Health Sciences (Department of Defense (DoD) Program); Grant sponsor: National Institute of Allergy and Infectious Diseases (in whole or in part); Grant sponsor: National Institutes of Health (NIH; Inter-Agency Agreement); Grant number: Y1-AI-5072. NR 16 TC 1 Z9 1 U1 0 U2 0 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 0146-6615 J9 J MED VIROL JI J. Med. Virol. PD SEP PY 2011 VL 83 IS 9 BP 1537 EP 1543 DI 10.1002/jmv.22155 PG 7 WC Virology SC Virology GA 790OW UT WOS:000292600100007 PM 21739443 ER PT J AU Park, S Chu, PC Lee, JH AF Park, Sunghyea Chu, Peter C. Lee, Jae-Hak TI Interannual-to-interdecadal variability of the Yellow Sea Cold Water Mass in 1967-2008: Characteristics and seasonal forcings SO JOURNAL OF MARINE SYSTEMS LA English DT Article DE Yellow Sea Cold Water Mass; Interannual-to-interdecadal variability; Seasonal forcings ID VALUE DECOMPOSITION ANALYSIS; PACIFIC DECADAL OSCILLATION; ASIAN WINTER MONSOON; ARCTIC OSCILLATION; SURFACE TEMPERATURE; THERMAL VARIABILITY; TROPICAL WESTERN; SUMMER MONSOON; JAPAN/EAST SEA; NORTH-PACIFIC AB We identified characteristics of interannual-to-interdecadal variability of the Yellow Sea Cold Water Mass and examined mechanisms to generate variability using the Korea Oceanographic Data Center dataset Regional/background variables (sea level pressure (SLP), surface air temperature (SAT), and sea surface temperature (SST)) and five climate indices were used to explore the linkage to seasonally-differential forcings. The first EOF mode (53%) represents warming/cooling over the entire bottom cold water with the dominant periods of 2-7 and 10-20 years. Three cold and two warm events occur in 1967-2008. The variability preliminarily attributes to previous winter surface forcings; however, summer surface forcings intensify bottom cold water temperature anomaly (BWTa) induced in the previous winter and also trigger a new anomaly, especially in the cold event after 1996. Cold events relate to the winter forcing (strengthening of the Siberian High, the Aleutian Low, East Asian Jet Stream, Pacific Decadal Oscillation, and Arctic Oscillation) and the summer forcing (increased SLP in the Asian continent and the Aleutian Islands and increased SST in the Kuroshio and the Alaskan Current). In both seasons, SST and SAT anomalies on the tropical to subtropical western North Pacific are strongly correlated to BWTa; however, mechanisms are different. (C) 2011 Elsevier B.V. All rights reserved. C1 [Park, Sunghyea; Chu, Peter C.] USN, Postgrad Sch, Dept Oceanog, Monterey, CA 93943 USA. [Lee, Jae-Hak] Korea Ocean Res & Dev Inst, Marine Environm & Climate Change Lab, Ansan, South Korea. RP Park, S (reprint author), USN, Postgrad Sch, Dept Oceanog, Monterey, CA 93943 USA. EM spark@nps.edu FU Naval Oceanographic Office; Office of Naval Research; Naval Postgraduate School FX This research was sponsored by the Naval Oceanographic Office, Office of Naval Research, and Naval Postgraduate School. We greatly thank Dr. S. W. Yeh (Korea Ocean Research & Development Institute, Korea) for insightful comments on the manuscript. NR 57 TC 20 Z9 23 U1 3 U2 17 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0924-7963 J9 J MARINE SYST JI J. Mar. Syst. PD SEP PY 2011 VL 87 IS 3-4 BP 177 EP 193 DI 10.1016/j.jmarsys.2011.03.012 PG 17 WC Geosciences, Multidisciplinary; Marine & Freshwater Biology; Oceanography SC Geology; Marine & Freshwater Biology; Oceanography GA 780HO UT WOS:000291845300002 ER PT J AU Cinotti, L Smith, CF Sekimoto, H Mansani, L Reale, M Sienicki, JJ AF Cinotti, Luciano Smith, Craig F. Sekimoto, Hiroshi Mansani, Luigi Reale, Marco Sienicki, James J. TI Lead-cooled system design and challenges in the frame of Generation IV International Forum SO JOURNAL OF NUCLEAR MATERIALS LA English DT Article AB The Generation IV International Forum (GIF) Technology Roadmap identified the Lead-cooled Fast Reactor (LFR) as a technology well suited for electricity generation, hydrogen production and actinide management in a closed fuel cycle. One of the most important features of the LFR is the fact that lead is a relatively inert coolant, a feature that conveys significant advantages in terms of safety, system simplification, and the consequent potential for economic performance. In 2004, the GIF LFR Provisional System Steering Committee was organized and began to develop the LFR System Research Plan. The committee selected two pool-type reactor concepts as candidates for international cooperation and joint development in the GIF framework: these are the Small Secure Transportable Autonomous Reactor (SSTAR); and the European Lead-cooled System (ELSY). The high boiling point (1745 degrees C) of lead has a beneficial impact to the safety of the system, whereas its high melting point (327.4 degrees C) requires new engineering strategies, especially for In-Service-Inspection and refuelling. Lead, especially at high temperatures, is also relatively corrosive towards structural materials. This necessitates that coolant purity and the level of dissolved oxygen be carefully controlled, in addition to the proper selection of structural materials. For the GIF LFR concepts, lead has been chosen as the coolant rather than Lead-Bismuth Eutectic primarily because of its greatly reduced generation of the alpha-emitting (210)Po isotope formed in the coolant. This results in significantly reduced levels of radioactive contamination of the coolant while minimizing the effect of decay power in the coolant from such contaminants; an additional consideration is the desire to eliminate dependence on bismuth which might be a limited resource. This paper provides an overview of the historical development of the LFR, a summary of the advantages and challenges associated with heavy liquid metal coolants, and an update of the current status of development of LFR concepts under consideration. The main characteristics of the SSTAR and ELSY systems are summarized, and the current status of design of each system is presented. Because of the significant recent efforts in the ELSY system design, greater emphasis is placed on the ELSY plant, with focus on the technological development and design provisions intended to overcome or alleviate recognized drawbacks to the use of heavy liquid metal coolants. In the case of the SSTAR system for which development has proceeded more slowly, a more limited summary is provided. It is noted that both systems share many of the same research needs and objectives thus providing a strong basis for international collaboration. (C) 2011 Elsevier B.V. All rights reserved. C1 [Cinotti, Luciano] ME Rivus, I-00186 Rome, Italy. [Smith, Craig F.] Lawrence Livermore Natl Lab, Monterey, CA 93943 USA. [Smith, Craig F.] USN, Postgrad Sch, Monterey, CA 93943 USA. [Sekimoto, Hiroshi] Tokyo Inst Technol, Meguro Ku, Tokyo 1528550, Japan. [Mansani, Luigi; Reale, Marco] Ansaldo Nucl SpA, I-16161 Genoa, Italy. [Sienicki, James J.] Argonne Natl Lab, Argonne, IL 60439 USA. RP Cinotti, L (reprint author), ME Rivus, Piazza Campitelli 2, I-00186 Rome, Italy. EM luciano.cinotti@merivus.it; cfsmith@nps.edu; hsekimot@nr.titech.ac.jp; luigi.mansani@ann.ansaldo.it; marco.reale@ann.ansaldo.it; sienicki@anl.gov NR 10 TC 21 Z9 21 U1 2 U2 19 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0022-3115 J9 J NUCL MATER JI J. Nucl. Mater. PD AUG 31 PY 2011 VL 415 IS 3 BP 245 EP 253 DI 10.1016/j.jnucmat.2011.04.042 PG 9 WC Materials Science, Multidisciplinary; Nuclear Science & Technology SC Materials Science; Nuclear Science & Technology GA 827QG UT WOS:000295442400004 ER PT J AU Kroupp, E Osin, D Starobinets, A Fisher, V Bernshtam, V Weingarten, L Maron, Y Uschmann, I Forster, E Fisher, A Cuneo, ME Deeney, C Giuliani, JL AF Kroupp, E. Osin, D. Starobinets, A. Fisher, V. Bernshtam, V. Weingarten, L. Maron, Y. Uschmann, I. Foerster, E. Fisher, A. Cuneo, M. E. Deeney, C. Giuliani, J. L. TI Ion Temperature and Hydrodynamic-Energy Measurements in a Z-Pinch Plasma at Stagnation SO PHYSICAL REVIEW LETTERS LA English DT Article AB The time history of the local ion kinetic energy in a stagnating plasma was determined from Doppler-dominated line shapes. Using independent determination of the plasma properties for the same plasma region, the data allowed for inferring the time-dependent ion temperature, and for discriminating the temperature from the total ion kinetic energy. It is found that throughout most of the stagnation period the ion thermal energy constitutes a small fraction of the total ion kinetic energy; the latter is dominated by hydrodynamic motion. Both the ion hydrodynamic and thermal energies are observed to decrease to the electron thermal energy by the end of the stagnation period. It is confirmed that the total ion kinetic energy available at the stagnating plasma and the total radiation emitted are in balance, as obtained in our previous experiment. The dissipation time of the hydrodynamic energy thus appears to determine the duration (and power) of the K emission. C1 [Kroupp, E.; Osin, D.; Starobinets, A.; Fisher, V.; Bernshtam, V.; Weingarten, L.; Maron, Y.] Weizmann Inst Sci, IL-76100 Rehovot, Israel. [Uschmann, I.; Foerster, E.] Univ Jena, Jena, Germany. [Foerster, E.] Helmholtz Inst Jena, D-07743 Jena, Germany. [Fisher, A.] Technion Israel Inst Technol, Fac Phys, Haifa, Israel. [Cuneo, M. E.] Sandia Natl Labs, Albuquerque, NM 87185 USA. [Deeney, C.] Dept Energy, Washington, DC USA. [Giuliani, J. L.] USN, Res Lab, Div Plasma Phys, Washington, DC 20375 USA. RP Kroupp, E (reprint author), Weizmann Inst Sci, IL-76100 Rehovot, Israel. FU U.S. DOE Center for High-Energy-Density; Minerva foundation; Israel Science Foundation FX We are very grateful to J. P. Apruzese, H. Strauss, A. L. Velikovich, E. Waisman, and N. Zabusky for invaluable discussions and reading the manuscript. We thank P. Meiri for skilled assistance. This work was supported by the U.S. DOE Center for High-Energy-Density, by the Minerva foundation, and by the Israel Science Foundation. NR 12 TC 17 Z9 17 U1 0 U2 7 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0031-9007 J9 PHYS REV LETT JI Phys. Rev. Lett. PD AUG 29 PY 2011 VL 107 IS 10 AR 105001 DI 10.1103/PhysRevLett.107.105001 PG 5 WC Physics, Multidisciplinary SC Physics GA 812XY UT WOS:000294328500005 PM 21981506 ER PT J AU Flom, SR Chi, SH Rosenberg, A Nyak, A Duncan, TV Therien, MJ Butler, JJ Montgomery, SR Beadie, G Shirk, JS AF Flom, Steven R. Chi, San-Hui Rosenberg, Armand Nyak, Animesh Duncan, Timothy V. Therien, Michael J. Butler, James J. Montgomery, Steven R. Beadie, Guy Shirk, James S. TI Excited state contributions to near infrared nonliner optical response SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract CT 242nd National Meeting of the American-Chemical-Society (ACS) CY AUG 28-SEP 01, 2011 CL Denver, CO SP Amer Chem Soc (ACS) C1 [Flom, Steven R.; Chi, San-Hui; Rosenberg, Armand; Beadie, Guy; Shirk, James S.] USN, Res Lab, Div Opt Sci, Washington, DC 20375 USA. [Nyak, Animesh; Therien, Michael J.] Duke Univ, Dept Chem, Durham, NC 27708 USA. [Butler, James J.] Univ Pacific, Dept Phys, Forest Grove, OR 97116 USA. [Montgomery, Steven R.] USN Acad, Dept Phys, Annapolis, MD 21402 USA. [Nyak, Animesh; Duncan, Timothy V.] Univ Penn, Dept Chem, Philadelphia, PA 19104 USA. EM flom@nrl.navy.mil NR 0 TC 0 Z9 0 U1 1 U2 3 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD AUG 28 PY 2011 VL 242 MA 389-PHYS PG 1 WC Chemistry, Multidisciplinary SC Chemistry GA 880BE UT WOS:000299378306167 ER PT J AU Guenthner, AJ Lamison, KR Yandek, GR Masurat, KC Reams, JT Cambrea, LR Mabry, JM AF Guenthner, Andrew J. Lamison, Kevin R. Yandek, Gregory R. Masurat, Kenneth C. Reams, Josiah T. Cambrea, Lee R. Mabry, Joseph M. TI Role of concurrent chemical and physical processes in determining the maximum use temperatures of thermosetting polymers for aerospace applications SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract CT 242nd National Meeting of the American-Chemical-Society (ACS) CY AUG 28-SEP 01, 2011 CL Denver, CO SP Amer Chem Soc (ACS) C1 [Reams, Josiah T.] USAF, Prop Directorate, Natl Res Council, Res Lab, Edwards Afb, CA 93524 USA. [Lamison, Kevin R.; Masurat, Kenneth C.] ERC Inc, Edwards Afb, CA 93524 USA. [Cambrea, Lee R.] USN, Air Warfare Ctr, China Lake, CA 93555 USA. EM andrew.guenthner@edwards.af.mil NR 0 TC 0 Z9 0 U1 0 U2 2 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD AUG 28 PY 2011 VL 242 MA 262-POLY PG 1 WC Chemistry, Multidisciplinary SC Chemistry GA 880BE UT WOS:000299378306848 ER PT J AU Heuer, WB Smith, AR Baril, S Boercker, JE Tischler, JG Foos, EE Yoon, W AF Heuer, William B. Smith, Anthony R. Baril, Sophie Boercker, Janice E. Tischler, Joseph G. Foos, Edward E. Yoon, Woojun TI Formation of nanocrystal films for photovoltaic applications SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract CT 242nd National Meeting of the American-Chemical-Society (ACS) CY AUG 28-SEP 01, 2011 CL Denver, CO SP Amer Chem Soc (ACS) C1 [Heuer, William B.] USN Acad, Dept Chem, Annapolis, MD 21402 USA. [Smith, Anthony R.; Baril, Sophie; Boercker, Janice E.; Tischler, Joseph G.; Foos, Edward E.; Yoon, Woojun] USN, Res Lab, Washington, DC 20375 USA. EM heuer@usna.edu RI Yoon, Woojun/H-9734-2013 OI Yoon, Woojun/0000-0002-1946-5372 NR 0 TC 0 Z9 0 U1 0 U2 4 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD AUG 28 PY 2011 VL 242 MA 111-INOR PG 1 WC Chemistry, Multidisciplinary SC Chemistry GA 880BE UT WOS:000299378303675 ER PT J AU Kutana, A Erwin, SC Kilin, DS AF Kutana, Alex Erwin, Steven C. Kilin, Dmitri S. TI Density matrix theory study of the dynamics of excited carriers in lead chalcogenide nanocrystals and nanowires SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract CT 242nd National Meeting of the American-Chemical-Society (ACS) CY AUG 28-SEP 01, 2011 CL Denver, CO SP Amer Chem Soc (ACS) C1 [Kutana, Alex; Erwin, Steven C.] USN, Ctr Computat Mat Sci, Res Lab, Washington, DC 20375 USA. [Kilin, Dmitri S.] Univ S Dakota, Dept Chem, Vermillion, SD 57069 USA. EM kutana@dave.nrl.navy.mil NR 2 TC 0 Z9 0 U1 0 U2 3 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD AUG 28 PY 2011 VL 242 MA 131-COMP PG 1 WC Chemistry, Multidisciplinary SC Chemistry GA 880BE UT WOS:000299378302060 ER PT J AU Melde, BJ Johnson, BJ Trammell, SA AF Melde, Brian J. Johnson, Brandy J. Trammell, Scott A. TI Application of nanoporous organosilicates to detection of nitroenergetic compounds and volatile hydrocarbon solvents SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract CT 242nd National Meeting of the American-Chemical-Society (ACS) CY AUG 28-SEP 01, 2011 CL Denver, CO SP Amer Chem Soc (ACS) C1 [Melde, Brian J.; Johnson, Brandy J.; Trammell, Scott A.] USN, Res Lab, Ctr Biomol Sci & Engn, Washington, DC 20375 USA. EM brian.melde@nrl.navy.mil RI Johnson, Brandy/B-3462-2008 OI Johnson, Brandy/0000-0002-3637-0631 NR 0 TC 0 Z9 0 U1 0 U2 4 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD AUG 28 PY 2011 VL 242 MA 39-INOR PG 1 WC Chemistry, Multidisciplinary SC Chemistry GA 880BE UT WOS:000299378304097 ER PT J AU Viner, VG Viner, G AF Viner, Veronika G. Viner, Gloria TI Comparison of initiators and their effects on frontal polymerization of a cyanate ester SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract CT 242nd National Meeting of the American-Chemical-Society (ACS) CY AUG 28-SEP 01, 2011 CL Denver, CO SP Amer Chem Soc (ACS) C1 [Viner, Veronika G.] China Lake Naval Air Warfare Ctr Weap Div, China Lake, CA 93555 USA. [Viner, Gloria] Louisiana State Univ, Dept Chem, Baton Rouge, LA 70803 USA. EM v_viner@yahoo.com NR 0 TC 0 Z9 0 U1 0 U2 2 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD AUG 28 PY 2011 VL 242 MA 626-POLY PG 1 WC Chemistry, Multidisciplinary SC Chemistry GA 880BE UT WOS:000299378307336 ER PT J AU Viner, VG Viner, G AF Viner, Veronika G. Viner, Gloria TI Effect of acrylate choice on binary frontal polymerization SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract CT 242nd National Meeting of the American-Chemical-Society (ACS) CY AUG 28-SEP 01, 2011 CL Denver, CO SP Amer Chem Soc (ACS) C1 [Viner, Veronika G.] China Lake Naval Air Warfare Ctr Weap Div, Dept Chem, China Lake, CA 93555 USA. [Viner, Gloria] Louisiana State Univ, Dept Chem, Baton Rouge, LA 70803 USA. EM v_viner@yahoo.com NR 0 TC 0 Z9 0 U1 0 U2 3 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD AUG 28 PY 2011 VL 242 MA 281-PMSE PG 1 WC Chemistry, Multidisciplinary SC Chemistry GA 880BE UT WOS:000299378306584 ER PT J AU Watson, KE Wynne, JH Yesinowski, JP Young, CN Clayton, CR Han, Y AF Watson, Kelly E. Wynne, James H. Yesinowski, James P. Young, Christopher N. Clayton, Clive R. Han, Young TI Mode of action of chemical paint strippers in removing robust polymeric coatings SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract CT 242nd National Meeting of the American-Chemical-Society (ACS) CY AUG 28-SEP 01, 2011 CL Denver, CO SP Amer Chem Soc (ACS) C1 [Watson, Kelly E.] Sci Applicat Int Corp, Washington, DC 20375 USA. [Wynne, James H.; Yesinowski, James P.] USN, Div Chem, Res Lab, Washington, DC 20375 USA. [Young, Christopher N.; Clayton, Clive R.] SUNY Stony Brook, Dept Mat Sci & Engn, Stony Brook, NY 11794 USA. [Han, Young] USN, Air Syst Command, Patuxent River, MD 20670 USA. EM kelly.e.watson@saic.com NR 0 TC 0 Z9 0 U1 2 U2 8 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD AUG 28 PY 2011 VL 242 MA 369-ENVR PG 1 WC Chemistry, Multidisciplinary SC Chemistry GA 880BE UT WOS:000299378302653 ER PT J AU Witko, E Korter, TM Wilkinson, J Ouellette, W Lightstone, J AF Witko, Ewelina Korter, Timothy M. Wilkinson, John Ouellette, Wayne Lightstone, James TI Terahertz spectroscopy and the use of London dispersion corrections in the solid-state density functional theory simulation of the explosive RDX SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract CT 242nd National Meeting of the American-Chemical-Society (ACS) CY AUG 28-SEP 01, 2011 CL Denver, CO SP Amer Chem Soc (ACS) C1 [Witko, Ewelina; Korter, Timothy M.] Syracuse Univ, Dept Chem, Syracuse, NY 13244 USA. [Wilkinson, John; Ouellette, Wayne; Lightstone, James] NSWC, Indian Head Div, Indian Head, MD 20640 USA. EM emwitko@syr.edu NR 0 TC 0 Z9 0 U1 0 U2 4 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD AUG 28 PY 2011 VL 242 MA 444-PHYS PG 1 WC Chemistry, Multidisciplinary SC Chemistry GA 880BE UT WOS:000299378306227 ER PT J AU Zhou, JC Chen, MS Bruckman, MA Soto, CM Ratna, BR Spies, BR Confer, TS AF Zhou, Jing C. Chen, Mu-San Bruckman, Michael A. Soto, Carissa M. Ratna, Banahalli R. Spies, Bradley R. Confer, Tammie S. TI Electroless deposition of metal clusters on Tobacco Mosaic Virus SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract CT 242nd National Meeting of the American-Chemical-Society (ACS) CY AUG 28-SEP 01, 2011 CL Denver, CO SP Amer Chem Soc (ACS) C1 [Zhou, Jing C.; Chen, Mu-San; Bruckman, Michael A.; Soto, Carissa M.; Ratna, Banahalli R.; Spies, Bradley R.; Confer, Tammie S.] USN, Res Lab, Washington, DC 20375 USA. EM jingczhou@yahoo.com NR 0 TC 0 Z9 0 U1 0 U2 7 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD AUG 28 PY 2011 VL 242 MA 129-COLL PG 1 WC Chemistry, Multidisciplinary SC Chemistry GA 880BE UT WOS:000299378301538 ER PT J AU Jarosz, E Teague, WJ Book, JW Besiktepe, S AF Jarosz, Ewa Teague, William J. Book, Jeffrey W. Besiktepe, Suekrue TI On flow variability in the Bosphorus Strait SO JOURNAL OF GEOPHYSICAL RESEARCH-OCEANS LA English DT Article ID SEA-LEVEL VARIATIONS; BLACK-SEA; EXCHANGE FLOW; CIRCULATION; ALTIMETER; MARMARA AB Two bottom-mounted acoustic Doppler current profilers and a vertical string of temperature, conductivity, and pressure sensors were deployed at each end of the Bosphorus Strait in September 2008 and remained in place for over 5 months. These observations showed a two-layer structure of the exchange flow in the Bosphorus Strait with brackish waters originating in the Black Sea moving southward and more saline, denser waters from the Sea of Marmara flowing northward. Considerable differences in mean flow, current fluctuations, and layer thickness were also found. In the northern Bosphorus, the current variations were more pronounced in the lower layer than in the upper layer. The opposite situation was observed in the southern Bosphorus where the upper layer currents fluctuated more noticeably. The near-surface currents often exceeded 200 cm/s in the southern section and were generally below 30 cm/s in the northern section. Currents usually below 70 cm/s were observed in the lower layer in the southern part of the strait, while the lower layer outflow to the Black Sea in the northern part of the strait frequently reached 100 cm/s, with flow concentrated in a strong midlayer maximum core. The upper layer thickness displayed temporal variability and, on average, was about 39 m near its northern end and about 14 m near its southern end. Flow variability was found to be closely associated with variability of the bottom pressure difference and the atmospheric forcing on the synoptic time scale (2-10 days). C1 [Jarosz, Ewa; Teague, William J.; Book, Jeffrey W.] USN, Res Lab, Stennis Space Ctr, MS 39529 USA. [Besiktepe, Suekrue] NATO Undersea Res Ctr, I-19126 La Spezia, Italy. RP Jarosz, E (reprint author), USN, Res Lab, Stennis Space Ctr, MS 39529 USA. EM ewa.jarosz@nrlssc.navy.mil RI Besiktepe, Sukru/L-2272-2013 OI Besiktepe, Sukru/0000-0002-9615-4746 FU Office of Naval Research as a part of the NRL [61153N] FX This work was supported by the Office of Naval Research as a part of the NRL's basic research project "Exchange Processes in Ocean Straits (EPOS)" under program element 61153N. We would like to thank everyone from the NATO NURC and the Turkish Navy Office of Navigation, Hydrography, and Oceanography who supported and helped to organize and fund cruises to the TSS on the R/V Alliance. We would like to thank Mark Hulbert, Andy Quaid, Wesley Goode, and Steve Sova, our technicians, for outstanding instrument preparation, mooring deployment, and recovery. We are also thankful and indebted to the crew of the R/V Alliance for helping with our mooring deployment and recovery that occurred in very challenging conditions. Finally, we would like to express our gratitude to Mikdat Kodioglu (Istanbul Technical University) for making meteorological observations available to us. NR 20 TC 15 Z9 15 U1 1 U2 6 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 0148-0227 J9 J GEOPHYS RES-OCEANS JI J. Geophys. Res.-Oceans PD AUG 27 PY 2011 VL 116 AR C08038 DI 10.1029/2010JC006861 PG 17 WC Oceanography SC Oceanography GA 813KI UT WOS:000294365100003 ER PT J AU Nyadjro, ES Subrahmanyam, B Shriver, JF AF Nyadjro, Ebenezer S. Subrahmanyam, Bulusu Shriver, Jay F. TI Seasonal variability of salt transport during the Indian Ocean monsoons SO JOURNAL OF GEOPHYSICAL RESEARCH-OCEANS LA English DT Article ID SEA-SURFACE SALINITY; GENERAL-CIRCULATION MODEL; TROPICAL PACIFIC-OCEAN; NORTHERN ARABIAN SEA; FRESH-WATER FLUXES; INDONESIAN THROUGHFLOW; SOUTHWEST MONSOON; MIXED-LAYER; WORLD OCEAN; ATLANTIC AB The seasonal variability of salinity transport in the Indian Ocean is investigated using the high-resolution global HYbrid Coordinate Ocean Model (HYCOM). Mechanisms and physical parameters that control the salinity budget are examined. Results show the influence of freshwater forcing and zonal advection as the dominant mechanisms of sea surface salinity (SSS) variability. Precipitation is highest in the eastern Bay of Bengal (BoB), where it shows seasonal variation, and in the south equatorial eastern Indian Ocean (EIO), where it was consistently high year-round. These patterns result in significant seasonal variation in the SSS in the BoB and almost no variation in the EIO. Zonal SSS transport was higher than meridional SSS transport with the strongest seasonality observed along the Sri Lankan region. Results of depth-integrated transport show northward salt transport in the bottom layers and a southward salt transport in the surface layers. The 4 year mean net flux of depth-integrated salt transport was southward (-154.8 x 10(6) kg/s to -552.4 x 10(6) kg/s) at all latitudes except at 20 degrees N, where it was northward (396 x 10(6) kg/s). Transport generally increases southward with the highest transports occurring in the south (10 degrees S-35 degrees S) and a maximum at 30 degrees S. Analyses of meridional Ekman volume and salt transport show a predominantly southward transport, an indication of the strong influence of SW monsoonal winds. It is anticipated that this study will be useful in computing salt transport using satellite-derived salinity data from the European Space Agency (ESA) Soil Moisture and Ocean Salinity (SMOS) and NASA Aquarius salinity missions. C1 [Nyadjro, Ebenezer S.; Subrahmanyam, Bulusu] Univ S Carolina, Marine Sci Program, Columbia, SC 29205 USA. [Subrahmanyam, Bulusu] Univ S Carolina, Dept Earth & Ocean Sci, Columbia, SC 29205 USA. [Shriver, Jay F.] USN, Res Lab, Stennis Space Ctr, MS 39529 USA. RP Nyadjro, ES (reprint author), Univ S Carolina, Marine Sci Program, Columbia, SC 29205 USA. EM enyadjro@geol.sc.edu FU Office of Naval Research (ONR) [N000141110700, 601153N] FX This work was supported by the Office of Naval Research (ONR) Award N000141110700 awarded to B.S. J.S. was supported by the 6.1 project "Global and Remote Littoral Forcing in the Global Ocean Models" sponsored by the Office of Naval Research (ONR) under the program element 601153N. The authors would like to thank two anonymous reviewers for all their helpful comments and suggestions. NR 69 TC 5 Z9 6 U1 1 U2 27 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 2169-9275 EI 2169-9291 J9 J GEOPHYS RES-OCEANS JI J. Geophys. Res.-Oceans PD AUG 27 PY 2011 VL 116 AR C08036 DI 10.1029/2011JC006993 PG 14 WC Oceanography SC Oceanography GA 813KI UT WOS:000294365100004 ER PT J AU Isidean, SD Riddle, MS Savarino, SJ Porter, CK AF Isidean, S. D. Riddle, M. S. Savarino, S. J. Porter, C. K. TI A systematic review of ETEC epidemiology focusing on colonization factor and toxin expression SO VACCINE LA English DT Review DE Enterotoxigenic Escherichia coli; ETEC; Colonization factor; Heat-stable toxin; Heat-labile toxin ID ENTEROTOXIGENIC ESCHERICHIA-COLI; HEAT-LABILE TOXIN; FACTOR ANTIGEN-I; US MILITARY PERSONNEL; ROTAVIRUS SURVEILLANCE NETWORK; KILLED ORAL VACCINE; 1ST 2 YEARS; ACUTE DIARRHEA; TRAVELERS DIARRHEA; VIRULENCE FACTORS AB Introduction: Vaccine development for enterotoxigenic Escherichia coli (ETEC) is dependent on in-depth understanding of toxin and colonization factor (CF) distribution. We sought to describe ETEC epidemiology across regions and populations, focusing on CF and toxin prevalence. Methods: We conducted a systematic review of the published literature, including studies reporting data on ETEC CF and toxin distributions among those with ETEC infection. Point estimates and confidence intervals were calculated using random effects models. Results: Data on 17,205 ETEC isolates were abstracted from 136 included studies. Approximately half of the studies (49%) involved endemic populations, and an additional 17% involved only travel populations. Globally, 60% of isolates expressed LT either alone (27%) or in combination with ST (33%). CFA/I-expressing strains were common in all regions (17%), as were ETEC expressing CFA/II (9%) and IV (18%). Marked variation in toxins and CFs across regions and populations was observed. Discussion/conclusions: These results demonstrate the relative importance of specific CFs in achieving target product profiles for a future ETEC vaccine. However, heterogeneity across time, population, and region, confounded by variability in CF and toxin detection methodologies, obfuscates rational estimates for valency requirements. Published by Elsevier Ltd. C1 [Isidean, S. D.; Riddle, M. S.; Savarino, S. J.; Porter, C. K.] USN, Enter Dis Dept, Infect Dis Directorate, Med Res Ctr, Silver Spring, MD 20910 USA. RP Porter, CK (reprint author), USN, Enter Dis Dept, Infect Dis Directorate, Med Res Ctr, 503 Robert Grant Ave, Silver Spring, MD 20910 USA. EM chad.porter@med.navy.mil RI Riddle, Mark/A-8029-2011 NR 177 TC 70 Z9 73 U1 3 U2 27 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0264-410X J9 VACCINE JI Vaccine PD AUG 26 PY 2011 VL 29 IS 37 BP 6167 EP 6178 DI 10.1016/j.vaccine.2011.06.084 PG 12 WC Immunology; Medicine, Research & Experimental SC Immunology; Research & Experimental Medicine GA 825AR UT WOS:000295243800006 PM 21723899 ER PT J AU Barnoy, S Baqar, S Kaminski, RW Collins, T Nemelka, K Hale, TL Ranallo, RT Venkatesan, MM AF Barnoy, S. Baqar, S. Kaminski, R. W. Collins, T. Nemelka, K. Hale, T. L. Ranallo, R. T. Venkatesan, M. M. TI Shigella sonnei vaccine candidates WRSs2 and WRSs3 are as immunogenic as WRSS1, a clinically tested vaccine candidate, in a primate model of infection SO VACCINE LA English DT Article DE Shigella sonnei; Live vaccine candidates; WRSs2; WRSs3 ID OUTER-MEMBRANE PROTEASE; FLEXNERI 2A; IMMUNE-RESPONSE; INTERCELLULAR SPREAD; ESCHERICHIA-COLI; RHESUS-MONKEYS; ORAL VACCINE; LIVE; SAFETY; INVASION AB Shigella causes diarrhea and dysentery through contaminated food and water. Shigella sonnei live vaccine candidates WRSs2 and WRSs3 are attenuated principally by the loss of VirG(IcsA) that prevents bacterial spread within the colonic epithelium. In this respect they are similar to the clinically tested vaccine candidate WRSS1. However, WRSs2 and WRSs3 are further attenuated by loss of senA, senB and WRSs3 also lacks msbB2. As previously shown in cell culture assays and in small animal models, these additional gene deletions reduced the levels of enterotoxicity and endotoxicity of WRSs2 and WRSs3, potentially making them safer than WRSS1. However the behavior of these second-generation VirG(IcsA)-based vaccine candidates in eliciting an immune response in a gastrointestinal model of infection has not been evaluated. In this study, WRSs2 and WRSs3 were nasogastrically administered to rhesus monkeys that were evaluated for colonization, as well as for systemic and mucosal immune responses. Both vaccine candidates were safe in rhesus monkeys and behaved comparably to WRSS1 in bacterial excretion rates that demonstrated robust intestinal colonization. Furthermore, humoral and mucosal immune responses elicited against bacterial antigens appeared similar in all categories across all three strains indicating that the additional gene deletions did not compromise the immunogenicity of these vaccine candidates. Based on data from previous clinical trials with WRSS1, it is likely that, WRSs2 and WRSs3 will not only be safer in human volunteers but will generate comparable levels of systemic and mucosal immune responses that were achieved with WRSS1. Published by Elsevier Ltd. C1 [Barnoy, S.; Kaminski, R. W.; Hale, T. L.; Ranallo, R. T.; Venkatesan, M. M.] Walter Reed Army Inst Res, Div Bacterial & Rickettsial Dis, Silver Spring, MD 20910 USA. [Baqar, S.] USN, Med Res Ctr, Infect Dis Directorate, Silver Spring, MD USA. [Collins, T.; Nemelka, K.] Walter Reed Army Inst Res, Div Vet Med, Silver Spring, MD USA. RP Venkatesan, MM (reprint author), Walter Reed Army Inst Res, Div Bacterial & Rickettsial Dis, 503 Robert Grant Ave, Silver Spring, MD 20910 USA. EM malabi.venkatesan@us.army.mil NR 58 TC 17 Z9 17 U1 1 U2 4 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0264-410X J9 VACCINE JI Vaccine PD AUG 26 PY 2011 VL 29 IS 37 BP 6371 EP 6378 DI 10.1016/j.vaccine.2011.04.115 PG 8 WC Immunology; Medicine, Research & Experimental SC Immunology; Research & Experimental Medicine GA 825AR UT WOS:000295243800030 PM 21596086 ER PT J AU Emmert, JT Picone, JM AF Emmert, J. T. Picone, J. M. TI Statistical uncertainty of 1967-2005 thermospheric density trends derived from orbital drag SO JOURNAL OF GEOPHYSICAL RESEARCH-SPACE PHYSICS LA English DT Article ID GLOBAL CHANGE; IONOSPHERE; DECREASE; SERIES AB Estimation of trend uncertainties is an essential element of long-term climate change study. Standard error analysis assumes independent (i.e., uncorrelated) random deviations of the data around the trend, a requirement that is rarely fulfilled by upper atmospheric time series; consequently, uncertainty estimates are typically unrealistically small. To obtain internally consistent estimates of linear trends and trend uncertainties in thermospheric density data, we account for correlated noise by incorporating autoregressive (AR) models of varying order into our error analysis. We apply our method to daily, monthly, and yearly averages of thermospheric mass density data derived from orbital drag, after subtracting out solar and seasonal effects. The resulting trend uncertainty estimates are mutually congruent among the three temporal cadences; in contrast, assuming independent random error produces uncertainty estimates that differ considerably among the daily, monthly, and yearly cases. At 400 km, we estimate the 1967-2005 density trend to be -1.94% per decade, with a 95% confidence interval of [-3.30, -0.59] % per decade. The AR model residuals are consistent with the assumption of independent, normally distributed random errors with uniform variance. Our methodology permits realistic analytical estimates of trend uncertainties for AR processes of arbitrary order, superseding the use of Monte Carlo simulations, and the approach is applicable to trend analysis of other upper atmospheric parameters. C1 [Emmert, J. T.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. [Picone, J. M.] George Mason Univ, Dept Phys & Astron, Fairfax, VA 22030 USA. RP Emmert, JT (reprint author), USN, Res Lab, Div Space Sci, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM john.emmert@nrl.navy.mil FU Office of Naval Research FX This work was supported by the Office of Naval Research. Orbit data were obtained from www.space-track.org. The authors thank J. Lean and R. Meier for helpful discussions. NR 31 TC 14 Z9 14 U1 0 U2 3 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 0148-0227 J9 J GEOPHYS RES-SPACE JI J. Geophys. Res-Space Phys. PD AUG 25 PY 2011 VL 116 AR A00H09 DI 10.1029/2010JA016382 PG 12 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 813KS UT WOS:000294366100001 ER PT J AU Singh, M Bettenhausen, MH AF Singh, Malkiat Bettenhausen, Michael H. TI An accurate and efficient algorithm for Faraday rotation corrections for spaceborne microwave radiometers SO RADIO SCIENCE LA English DT Article ID GPS DATA; IONOSPHERE; SPECIFICATION; MODELS AB Faraday rotation changes the polarization plane of linearly polarized microwaves which propagate through the ionosphere. To correct for ionospheric polarization error, it is necessary to have electron density profiles on a global scale that represent the ionosphere in real time. We use raytrace through the combined models of ionospheric conductivity and electron density (ICED), Bent, and Gallagher models (RIBG model) to specify the ionospheric conditions by ingesting the GPS data from observing stations that are as close as possible to the observation time and location of the space system for which the corrections are required. To accurately calculate Faraday rotation corrections, we also utilize the raytrace utility of the RIBG model instead of the normal shell model assumption for the ionosphere. We use WindSat data, which exhibits a wide range of orientations of the raypath and a high data rate of observations, to provide a realistic data set for analysis. The standard single-shell models at 350 and 400 km are studied along with a new three-shell model and compared with the raytrace method for computation time and accuracy. We have compared the Faraday results obtained with climatological (International Reference Ionosphere and RIBG) and physics-based (Global Assimilation of Ionospheric Measurements) ionospheric models. We also study the impact of limitations in the availability of GPS data on the accuracy of the Faraday rotation calculations. C1 [Singh, Malkiat] Computat Phys Inc, Springfield, VA 22151 USA. [Bettenhausen, Michael H.] USN, Remote Sensing Branch, Remote Sensing Div, Res Lab, Washington, DC 20375 USA. RP Singh, M (reprint author), Computat Phys Inc, 8001 Braddock Rd,Ste 201, Springfield, VA 22151 USA. EM smalkiat@yahoo.com NR 23 TC 0 Z9 0 U1 0 U2 0 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 0048-6604 J9 RADIO SCI JI Radio Sci. PD AUG 25 PY 2011 VL 46 AR RS4008 DI 10.1029/2010RS004509 PG 16 WC Astronomy & Astrophysics; Geochemistry & Geophysics; Meteorology & Atmospheric Sciences; Remote Sensing; Telecommunications SC Astronomy & Astrophysics; Geochemistry & Geophysics; Meteorology & Atmospheric Sciences; Remote Sensing; Telecommunications GA 813KB UT WOS:000294364300001 ER PT J AU Wijesundara, KC Rolon, JE Ulloa, SE Bracker, AS Gammon, D Stinaff, EA AF Wijesundara, Kushal C. Rolon, Juan E. Ulloa, Sergio E. Bracker, Allan S. Gammon, Daniel Stinaff, Eric A. TI Tunable exciton relaxation in vertically coupled semiconductor InAs quantum dots SO PHYSICAL REVIEW B LA English DT Article AB Tunable exciton relaxation rates are observed in individual vertically coupled semiconductor quantum dots (CQDs). An applied electric field is used to tune the energy difference between the spatially direct (SD) and indirect (SI) excitons in InAs CQDs. The intensity and lifetime of the SI exciton is found to vary as a result of wave-function distribution, carrier tunneling, and phonon-mediated relaxation effects. This includes a modulation of the phonon relaxation rate between the SI and SD excitons, a consequence of momentum space restrictions resulting from the structure factor of the CQD. C1 [Wijesundara, Kushal C.; Rolon, Juan E.; Ulloa, Sergio E.; Stinaff, Eric A.] Ohio Univ, Dept Phys & Astron, Nanoscale & Quantum Phenomena Inst, Athens, OH 45701 USA. [Bracker, Allan S.; Gammon, Daniel] USN, Res Lab, Washington, DC 20375 USA. RP Stinaff, EA (reprint author), Ohio Univ, Dept Phys & Astron, Nanoscale & Quantum Phenomena Inst, Athens, OH 45701 USA. EM stinaff@ohio.edu RI Ulloa, Sergio/F-4621-2011; OI Ulloa, Sergio/0000-0002-3091-4984; Rolon, Juan E/0000-0002-6104-9321 FU NSF [DMR-1005525]; NSA/LPS; MURI/Army; Ohio University CMSS; NQPI FX This work was supported by the NSF (DMR-1005525, MWN/CIAM, and PIRE grants), NSA/LPS, MURI/Army, and the Ohio University CMSS and NQPI programs. We thank Alexander Govorov for helpful discussions. NR 23 TC 12 Z9 12 U1 0 U2 14 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1098-0121 J9 PHYS REV B JI Phys. Rev. B PD AUG 25 PY 2011 VL 84 IS 8 AR 081404 DI 10.1103/PhysRevB.84.081404 PG 4 WC Physics, Condensed Matter SC Physics GA 812CT UT WOS:000294266000002 ER PT J AU Blanton, EL Randall, SW Clarke, TE Sarazin, CL McNamara, BR Douglass, EM McDonald, M AF Blanton, E. L. Randall, S. W. Clarke, T. E. Sarazin, C. L. McNamara, B. R. Douglass, E. M. McDonald, M. TI A VERY DEEP CHANDRA OBSERVATION OF A2052: BUBBLES, SHOCKS, AND SLOSHING SO ASTROPHYSICAL JOURNAL LA English DT Article DE galaxies: active; galaxies: clusters: general; galaxies: clusters: individual (A2052); galaxies: clusters: intracluster medium; radio continuum: galaxies; X-rays: galaxies: clusters ID FLOW CLUSTER ABELL-2052; GALACTIC NUCLEUS FEEDBACK; RAY-EMITTING GAS; X-RAY; GALAXY CLUSTERS; COOLING FLOWS; COLD FRONTS; PERSEUS CLUSTER; GASEOUS ATMOSPHERE; RADIO-SOURCE AB We present the first results from a very deep (similar to 650 ks) Chandra X-ray observation of A2052, as well as archival Very Large Array radio observations. The data reveal detailed structure in the inner parts of the cluster, including bubbles evacuated by radio lobes of the active galactic nucleus (AGN), compressed bubble rims, filaments, and loops. Two concentric shocks are seen, and a temperature rise is measured for the innermost one. On larger scales, we report the first detection of an excess surface brightness spiral feature. The spiral has cooler temperatures, lower entropies, and higher abundances than its surroundings, and is likely the result of sloshing gas initiated by a previous cluster-cluster or sub-cluster merger. Initial evidence for previously unseen bubbles at larger radii related to earlier outbursts from the AGN is presented. C1 [Blanton, E. L.; Douglass, E. M.] Boston Univ, Dept Astron, Boston, MA 02215 USA. [Blanton, E. L.; Randall, S. W.; McNamara, B. R.] Harvard Smithsonian Ctr Astrophys, Cambridge, MA 02138 USA. [Clarke, T. E.] USN, Res Lab, Washington, DC 20375 USA. [Sarazin, C. L.] Univ Virginia, Dept Astron, Charlottesville, VA 22904 USA. [McNamara, B. R.] Univ Waterloo, Dept Phys & Astron, Waterloo, ON N2L 2G1, Canada. [Douglass, E. M.] Perimeter Inst Theoret Phys, Waterloo, ON N2L 2Y5, Canada. [McDonald, M.] Univ Maryland, Dept Astron, College Pk, MD 20742 USA. [Blanton, E. L.; Douglass, E. M.] Boston Univ, Inst Astrophys Res, Boston, MA 02215 USA. RP Blanton, EL (reprint author), Harvard Smithsonian Ctr Astrophys, 60 Garden St, Cambridge, MA 02138 USA. EM eblanton@bu.edu; srandall@head.cfa.harvard.edu; tracy.clarke@nrl.navy.mil; sarazin@virginia.edu; mcnamara@sciborg.uwaterloo.ca; emdoug@bu.edu; mcdonald@astro.umd.edu RI Blanton, Elizabeth/H-4501-2014; OI Randall, Scott/0000-0002-3984-4337 FU National Aeronautics and Space Administration [GO9-0147X]; Chandra X-ray Center through NASA [NAS8-03060] FX Support for this work was provided by the National Aeronautics and Space Administration, through Chandra Award Number GO9-0147X. Basic research in radio astronomy at the Naval Research Laboratory is supported by 6.1 Base funding. S. W. R. was supported in part by the Chandra X-ray Center through NASA contract NAS8-03060. We thank Frazer Owen for useful discussions. NR 48 TC 58 Z9 58 U1 0 U2 3 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X J9 ASTROPHYS J JI Astrophys. J. PD AUG 20 PY 2011 VL 737 IS 2 AR 99 DI 10.1088/0004-637X/737/2/99 PG 21 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 808WV UT WOS:000294013600053 ER PT J AU Halterman, K Valls, OT Alidoust, M AF Halterman, Klaus Valls, Oriol T. Alidoust, Mohammad TI Characteristic energies, transition temperatures, and switching effects in clean S vertical bar N vertical bar S graphene nanostructures SO PHYSICAL REVIEW B LA English DT Article ID SUPERCONDUCTORS; SUPERCURRENT; TRANSPORT AB We study proximity effects in clean nanoscale superconductor-normal-metal-superconductor (S|N|S) graphene heterostructures using a self-consistent numerical solution to the continuum Dirac Bogoliubov-de Gennes (DBdG) equations. We obtain results for the pair amplitude and the local density of states (DOS) as a function of doping and of the geometrical parameters determining the width of the structures. The superconducting correlations are found to penetrate the normal graphene layers even when there is extreme mismatch in the normal and superconducting doping levels, where specular Andreev reflection dominates. The local DOS exhibits peculiar features, which we discuss, arising from the Dirac cone dispersion relation and from the interplay between the superconducting and Thouless energy scales. The corresponding characteristic energies emerge in the form of resonant peaks in the local DOS, which depend strongly on the doping level, as does the energy gap, which declines sharply as the relative difference in doping between the S and N regions is reduced. We also linearize the DBdG equations and develop an essentially analytical method that determines the critical temperature T-c of a S|N|S nanostructure self-consistently. We find that for S regions that occupy a fraction of the coherence length, T-c can undergo substantial variations as a function of the relative doping. At finite temperatures and by manipulating the doping levels, the self-consistent pair amplitudes reveal dramatic transitions between a superconducting and resistive normal state of the structure. Such behavior suggests the possibility of using the proposed system as a carbon-based superconducting switch, turning superconductivity on or off by tuning the relative doping levels. C1 [Halterman, Klaus] USN, Michelson Lab, Div Phys, Air Warfare Ctr, China Lake, CA 93555 USA. [Valls, Oriol T.] Univ Minnesota, Sch Phys & Astron, Minneapolis, MN 55455 USA. [Alidoust, Mohammad] Norwegian Univ Sci & Technol, Dept Phys, N-7491 Trondheim, Norway. [Valls, Oriol T.] Univ Minnesota, Minnesota Supercomp Inst, Minneapolis, MN 55455 USA. [Alidoust, Mohammad] Univ Isfahan, Dept Phys, Fac Sci, Esfahan 8174673441, Iran. RP Halterman, K (reprint author), USN, Michelson Lab, Div Phys, Air Warfare Ctr, China Lake, CA 93555 USA. EM klaus.halterman@navy.mil; otvalls@umn.edu; mohammad.alidoust@ntnu.no RI Halterman, Klaus/G-3826-2012; OI Halterman, Klaus/0000-0002-6355-3134; Alidoust, Mohammad/0000-0002-1554-687X FU ONR; DOD (HPCMP); Minnesota Supercomputer Institute FX This work is supported in part by ONR and by grants of HPC resources from DOD (HPCMP) and from the Minnesota Supercomputer Institute. M. A. wishes to thank J. Linder for conversations. NR 47 TC 5 Z9 5 U1 0 U2 10 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 2469-9950 EI 2469-9969 J9 PHYS REV B JI Phys. Rev. B PD AUG 19 PY 2011 VL 84 IS 6 AR 064509 DI 10.1103/PhysRevB.84.064509 PG 13 WC Physics, Condensed Matter SC Physics GA 809KV UT WOS:000294055000011 ER PT J AU Sauer, KL Klug, CA Miller, JB Yesinowski, JP AF Sauer, K. L. Klug, C. A. Miller, J. B. Yesinowski, J. P. TI Optically pumped InP: Nuclear polarization from NMR frequency shifts SO PHYSICAL REVIEW B LA English DT Article ID ELECTRON-SPIN-RESONANCE; MAGNETIC-FIELD; INDIUM-PHOSPHIDE; GALLIUM-ARSENIDE; P-31 NMR; SEMICONDUCTORS; DEPENDENCE; GAAS; NANOSTRUCTURES; TRANSITIONS AB There are a number of mechanisms that can produce frequency shifts in the NMR spectra of optically pumped semiconductors, including the hyperfine interaction, nuclear dipolar fields, and indirect or J couplings. Using optically pumped Fe-doped InP, we explore how to experimentally distinguish these shift mechanisms from one another, and then exploit the shifts to measure the absolute nuclear polarization. Furthermore, we optically pump, using circularly polarized light, at a much lower field (2.35 T) than previous work, permitting us to explore the field dependence of the nuclear polarization rate, the spin-lattice relaxation time, and the NMR photon energy spectrum. We measure similar polarizations as obtained at higher fields, but with a significantly faster nuclear polarization rate, making operation at lower fields attractive for optically pumped InP as a source of nuclear spin polarization. C1 [Sauer, K. L.; Klug, C. A.; Miller, J. B.; Yesinowski, J. P.] USN, Res Lab, Div Chem, Washington, DC 20375 USA. [Sauer, K. L.] George Mason Univ, Dept Phys & Astron, Fairfax, VA 22030 USA. RP Miller, JB (reprint author), USN, Res Lab, Div Chem, Code 6122, Washington, DC 20375 USA. FU Office of Naval Research; NSF [0547987] FX We wish to thank Dr. Robert Tycko for providing the Fe-doped InP sample used in these studies, Dr. Sean Hart for the use of his lasers, and Professor Jerry Miller for help with probe construction. This work was supported by the Office of Naval Research. One of us (KLS) acknowledges support in part by NSF Grant No. 0547987. NR 56 TC 11 Z9 11 U1 1 U2 12 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 2469-9950 EI 2469-9969 J9 PHYS REV B JI Phys. Rev. B PD AUG 19 PY 2011 VL 84 IS 8 AR 085202 DI 10.1103/PhysRevB.84.085202 PG 12 WC Physics, Condensed Matter SC Physics GA 809LL UT WOS:000294057100009 ER PT J AU Guenthner, AJ Davis, MC Lamison, KR Yandek, GR Cambrea, LR Groshens, TJ Baldwin, LC Mabry, JM AF Guenthner, Andrew J. Davis, Matthew C. Lamison, Kevin R. Yandek, Gregory R. Cambrea, Lee R. Groshens, Thomas J. Baldwin, Lawrence C. Mabry, Joseph M. TI Synthesis, cure kinetics, and physical properties of a new tricyanate ester with enhanced molecular flexibility SO POLYMER LA English DT Article DE Cyanate ester; Cure kinetics; Activation energy ID LAYERED SILICATE NANOCOMPOSITES; CYANATE ESTER; THERMOSET CURE; DICYANATE; RESINS; BLENDS; LIQUID AB 1,2,3-Tris(4-cyanatophenyl)propane, a new tricyanate ester monomer that was designed to incorporate more flexible chemical linkages at junction points in the cured macromolecular network, was synthesized in nine steps with an overall yield of 26%. The highly purified monomer exhibited an activation energy of 110 kJ/mol for auto-catalytic cure at temperatures of 210 degrees C-290 degrees C, modestly lower than the comparably measured activation energy of a commercial cyanated novolac. The overall extent of cure achievable at these temperatures was also higher for the new monomer. Many physical properties of the cured monomer, including density, thermochemical stability, moisture uptake, and the impact of hydrolytic degradation on glass transition temperature were similar to those of commercial tricyanates, with a dry glass transition temperature at full conversion of at least 340 degrees C. These results illustrate how careful control of the local chemical structure in the vicinity of network junction points may be utilized to improve the properties of thermosetting polymer networks. Published by Elsevier Ltd. C1 [Guenthner, Andrew J.; Yandek, Gregory R.; Mabry, Joseph M.] USAF, Res Lab, Edwards AFB, CA 93524 USA. [Davis, Matthew C.; Cambrea, Lee R.; Groshens, Thomas J.; Baldwin, Lawrence C.] Naval Air Warfare Ctr, Weap Div, China Lake, CA 93555 USA. [Lamison, Kevin R.] ERC Corp, Edwards AFB, CA 93524 USA. RP Guenthner, AJ (reprint author), USAF, Res Lab, Edwards AFB, CA 93524 USA. EM andrew.guenthner@edwards.af.mil FU Office of Naval Research; Air Force Office of Scientific Research FX Financial support through an In-house Laboratory Independent Research award from the Office of Naval Research, as well as funding from the Air Force Office of Scientific Research, is gratefully acknowledged. NR 40 TC 12 Z9 12 U1 0 U2 11 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0032-3861 J9 POLYMER JI Polymer PD AUG 18 PY 2011 VL 52 IS 18 BP 3933 EP 3942 DI 10.1016/j.polymer.2011.07.024 PG 10 WC Polymer Science SC Polymer Science GA 812TQ UT WOS:000294316200008 ER PT J AU Halterman, K Feng, SM Nguyen, VC AF Halterman, Klaus Feng, Simin Viet Cuong Nguyen TI Controlled leaky wave radiation from anisotropic epsilon near zero metamaterials SO PHYSICAL REVIEW B LA English DT Article ID ELECTROMAGNETIC ENERGY; PROPAGATION; INDEX; REFRACTION; ANGLE; LAYER AB We investigate the emission of electromagnetic waves from biaxial subwavelength metamaterials. For anisotropic structures that exhibit a vanishing dielectric response along the longitudinal axis and possess a tunable transverse dielectric response, we find remarkable variation in the launch angles of energy associated with the emission of leaky wave radiation. We write closed-form expressions for the energy transport velocity and corresponding radiation angle phi, defining the cone of radiation emission, as functions both of frequency and of material and geometrical parameters. Full wave simulations exemplify the broad range of directivity that can be achieved in these structures. C1 [Halterman, Klaus; Feng, Simin] USN, Air Warfare Ctr, Michelson Lab, Div Phys, China Lake, CA 93555 USA. [Viet Cuong Nguyen] Nanyang Technol Univ, Sch Elect & Elect Engn, Photon Res Ctr, Singapore 639798, Singapore. RP Halterman, K (reprint author), USN, Air Warfare Ctr, Michelson Lab, Div Phys, China Lake, CA 93555 USA. RI Halterman, Klaus/G-3826-2012; OI Nguyen, Viet Cuong/0000-0003-1145-5652; Halterman, Klaus/0000-0002-6355-3134 FU ONR; HPC resources as part of the DOD HPCMP FX K.H. is supported in part by ONR and a grant of HPC resources as part of the DOD HPCMP. NR 35 TC 14 Z9 14 U1 1 U2 16 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1098-0121 EI 1550-235X J9 PHYS REV B JI Phys. Rev. B PD AUG 18 PY 2011 VL 84 IS 7 AR 075162 DI 10.1103/PhysRevB.84.075162 PG 7 WC Physics, Condensed Matter SC Physics GA 809BV UT WOS:000294026600001 ER PT J AU Ollier, J Simpson, J Riley, MA Paul, ES Wang, X Aguilar, A Carpenter, MP Darby, IG Hartley, DJ Janssens, RVF Kondev, FG Lauritsen, T Nolan, PJ Petri, M Rigby, SV Teal, C Thomson, J Unsworth, C Zhu, S AF Ollier, J. Simpson, J. Riley, M. A. Paul, E. S. Wang, X. Aguilar, A. Carpenter, M. P. Darby, I. G. Hartley, D. J. Janssens, R. V. F. Kondev, F. G. Lauritsen, T. Nolan, P. J. Petri, M. Rigby, S. V. Teal, C. Thomson, J. Unsworth, C. Zhu, S. TI High-spin yrast structure of Ho-159 SO PHYSICAL REVIEW C LA English DT Article ID RARE-EARTH NUCLEI; BAND-STRUCTURE; SPECTROSCOPY; SYSTEMATICS; ENERGIES; STATES; MODEL AB An investigation of the yrast structure of the odd-Z Ho-159 nucleus to high spin has been performed. The Ho-159 nucleus was populated by the reaction Cd-116(Ca-48, p4n gamma) at a beam energy of 215 MeV, and resulting gamma decays were detected by the Gammasphere spectrometer. The h(11/2) yrast band has been significantly extended up to I-pi = 75/2(-)( tentatively 79/2(-)). A lower frequency limit for the second (h(11/2))(2) proton alignment was extracted consistent with the systematics of this alignment frequency, indicating an increased deformation with neutron number in the Ho isotopes. The energy-level splitting between the signature partners in the h11/2 structures of the Ho isotopes and the neighboring N = 92 isotones is discussed. C1 [Ollier, J.; Simpson, J.] STFC Daresbury Lab, Warrington WA4 4AD, Cheshire, England. [Riley, M. A.; Wang, X.; Aguilar, A.; Teal, C.] Florida State Univ, Dept Phys, Tallahassee, FL 32306 USA. [Paul, E. S.; Nolan, P. J.; Petri, M.; Rigby, S. V.; Thomson, J.; Unsworth, C.] Univ Liverpool, Oliver Lodge Lab, Liverpool L69 7ZE, Merseyside, England. [Carpenter, M. P.; Janssens, R. V. F.; Lauritsen, T.; Zhu, S.] Argonne Natl Lab, Div Phys, Argonne, IL 60439 USA. [Darby, I. G.] Univ Tennessee, Dept Phys & Astron, Knoxville, TN 37996 USA. [Hartley, D. J.] USN Acad, Dept Phys, Annapolis, MD 21402 USA. [Kondev, F. G.] Argonne Natl Lab, Nucl Engn Div, Argonne, IL 60439 USA. RP Ollier, J (reprint author), STFC Daresbury Lab, Warrington WA4 4AD, Cheshire, England. RI Carpenter, Michael/E-4287-2015; Petri, Marina/H-4630-2016 OI Carpenter, Michael/0000-0002-3237-5734; Petri, Marina/0000-0002-3740-6106 FU U.S. National Science Foundation [PHY-0756474, PHY-0554762]; U.S. Department of Energy, Office of Nuclear Physics [DE-AC02-06CH11357, DE-FG02-94ER40834, DE-FG02-96ER40983]; United Kingdom Science and Technology Facilities Council; State of Florida FX The authors acknowledge Paul Morrall for preparing the targets and the ATLAS operations staff for assistance. This work has been supported in part by the U.S. National Science Foundation under Grants No. PHY-0756474 (FSU) and No. PHY-0554762 (USNA); the U.S. Department of Energy, Office of Nuclear Physics, under Contracts No. DE-AC02-06CH11357 (ANL), No. DE-FG02-94ER40834 (UMD), and No. DE-FG02-96ER40983(UTK); the United Kingdom Science and Technology Facilities Council; and by the State of Florida. NR 35 TC 1 Z9 1 U1 0 U2 6 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0556-2813 EI 1089-490X J9 PHYS REV C JI Phys. Rev. C PD AUG 17 PY 2011 VL 84 IS 2 AR 027302 DI 10.1103/PhysRevC.84.027302 PG 4 WC Physics, Nuclear SC Physics GA 808JR UT WOS:000293974500005 ER PT J AU Knox, J Orchowski, J Scher, DL Owens, BD Burks, R Belmont, PJ AF Knox, Jeffrey Orchowski, Joseph Scher, Danielle L. Owens, Brett D. Burks, Robert Belmont, Philip J., Jr. TI The Incidence of Low Back Pain in Active Duty United States Military Service Members SO SPINE LA English DT Article DE epidemiology; low back pain; military; demographic ID RISK-FACTORS; MARITAL DISSATISFACTION; NATIONAL SURVEYS; NECK PAIN; PREVALENCE; HEALTH; POPULATION; INJURY; COHORT; ADULTS AB Study Design. Epidemiological study. Objective. To investigate the incidence and risk factors for developing low back pain in active duty military population to include age, sex, race, and rank, and military service. Summary of Background Data. Low back pain is among the most common musculoskeletal conditions worldwide and is estimated to affect nearly two-thirds of the US population at some point in their lives. Low back pain is a multifactorial disease and many risk factors have been implicated including age, race, sex, and marital status. Methods. A query was performed using the US Defense Medical Epidemiology Database (DMED) for the International Classification of Diseases, Ninth Revision, Clinical Modification code for low back pain (724.20). 13,754,261 person-years of data were investigated. Multivariate Poisson regression analysis was used to estimate the rate of low back pain per 1000 person-years, whereas controlling for sex, race, rank, service, age, and marital status. Results. The overall unadjusted incidence rate of low back pain was 40.5 per 1000 person-years. Women, compared with men, had a significantly increased incidence rate ratio for low back pain of 1.45. The incidence rate ratio for the 40+ age group compared with the 20 to 29 years of age group was 1.28. With junior officers as the referent category, junior-and senior-enlisted rank groups had increased incidence rate ratio for low back pain, 1.95 and 1.35, respectively. Each service, when compared with the Marines as the referent category, had a significantly increased incidence rate ratio of low back pain: Army: 2.19, Navy: 1.02, and Air Force: 1.54. Compared with single service members, significantly increased incidence rate ratio for low back pain were seen in married service members: 1.21. Conclusion. Female sex, enlisted rank groups, service in the Army, Navy, or Air Force, age greater than 40 years, and a marital status of married were all risk factors for low back pain. C1 [Knox, Jeffrey; Orchowski, Joseph] Tripler Army Med Ctr, Orthopaed Surg Serv, Dept Surg, Honolulu, HI 96859 USA. [Scher, Danielle L.; Belmont, Philip J., Jr.] William Beaumont Army Med Ctr, Orthopaed Surg Serv, Dept Surg, El Paso, TX 79920 USA. [Owens, Brett D.] Keller Army Hosp, Orthopaed Surg Serv, Dept Surg, West Point, NY USA. [Burks, Robert] USN, Postgrad Sch, Grad Sch Operat & Informat Sci, Monterey, CA USA. RP Knox, J (reprint author), Tripler Army Med Ctr, Dept Orthopaed Surg, 1 Jarrett White Rd, Honolulu, HI 96859 USA. EM jeffrey.bruce.knox@us.army.mil RI Burks, Robert/J-2481-2015; OI Burks, Robert/0000-0001-6443-6653; Belmont, Philip/0000-0003-2618-199X NR 51 TC 32 Z9 34 U1 0 U2 7 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0362-2436 J9 SPINE JI SPINE PD AUG 15 PY 2011 VL 36 IS 18 BP 1492 EP 1500 DI 10.1097/BRS.0b013e3181f40ddd PG 9 WC Clinical Neurology; Orthopedics SC Neurosciences & Neurology; Orthopedics GA 803KD UT WOS:000293579300020 PM 21224777 ER PT J AU Nagareddy, VK Nikitina, IP Gaskill, DK Tedesco, JL Myers-Ward, RL Eddy, CR Goss, JP Wright, NG Horsfall, AB AF Nagareddy, V. K. Nikitina, I. P. Gaskill, D. K. Tedesco, J. L. Myers-Ward, R. L. Eddy, C. R. Goss, J. P. Wright, N. G. Horsfall, A. B. TI High temperature measurements of metal contacts on epitaxial graphene SO APPLIED PHYSICS LETTERS LA English DT Article ID RAMAN-SPECTROSCOPY; INTERFACE; SURFACES AB Electrical characteristics of Cr/Au and Ti/Au metal contacts on epitaxial graphene on 4H-SiC showed significant variations in resistance parameters at 300 K. These parameters decreased substantially as the temperature increased to 673 K. The work function, binding energy, and diffusion energy of the deposited metals were used to explain these observed variations. The quantitative analysis of our data demonstrates that non-reactive metals with higher work functions result in lower contact resistance, which can be further decreased by 70% using appropriate annealing. These results provide important information when considering epitaxial graphene for high temperature applications. (C) 2011 American Institute of Physics. [doi:10.1063/1.3627167] C1 [Nagareddy, V. K.; Nikitina, I. P.; Goss, J. P.; Wright, N. G.; Horsfall, A. B.] Newcastle Univ, Sch Elect Elect & Comp Engn, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England. [Gaskill, D. K.; Tedesco, J. L.; Myers-Ward, R. L.; Eddy, C. R.] USN, Res Lab, Washington, DC 20375 USA. RP Nagareddy, VK (reprint author), Newcastle Univ, Sch Elect Elect & Comp Engn, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England. EM v.k.nagareddy@newcastle.ac.uk RI Wright, Nick/O-1092-2013; Nagareddy, Karthik/F-3380-2014; OI Nagareddy, Karthik/0000-0002-8765-3834; Wright, Nicholas/0000-0003-3169-4159 FU BAE Systems; ASEE; U.S. Office of Naval Research; EPSRC, UK FX V. K. N. is grateful for studentship support from BAE Systems through DHPA scheme. J. L. T. is grateful for post-doctoral support from ASEE. Portions of this work were supported by the U.S. Office of Naval Research and the EPSRC, UK. NR 23 TC 21 Z9 21 U1 0 U2 27 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD AUG 15 PY 2011 VL 99 IS 7 AR 073506 DI 10.1063/1.3627167 PG 3 WC Physics, Applied SC Physics GA 811KP UT WOS:000294208900069 ER PT J AU Simpkins, BS Mastro, MA Eddy, CR Hite, JK Pehrsson, PE AF Simpkins, B. S. Mastro, M. A. Eddy, C. R., Jr. Hite, J. K. Pehrsson, P. E. TI Space-charge-limited currents and trap characterization in coaxial AlGaN/GaN nanowires SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID CHEMICAL-VAPOR-DEPOSITION; GAN-NANOWIRES; HETEROSTRUCTURES; TRANSISTORS; DEVICES; GROWTH; HEMTS AB This manuscript presents the first observation of the space-charge-limited current (SCLC) conduction mechanism in individual heterostructure nanowires (NWs). This effect is exploited to extract size-dependent carrier densities and to demonstrate surface-dominated behavior for these technologically relevant nanostructures. Mobile carrier densities were shown to increase from 2.5 x 10(16) to 5.6 x 10(17) cm(-3), as NW width decreased from 200 to 50 nm. This size-dependent behavior is a consequence of the increasing influence of near-surface confined carriers as widths decrease. Traps impact the SCLC response and were characterized as an exponential band edge tail with an average characteristic energy of 75 meV. In addition to the specific materials properties extracted, these results further demonstrate the tendency for low-dimensional materials (1D NWs) to exhibit SCLC at much lower injection fluxes compared to their higher dimensional (2D heterostructure field-effect transistors) counterparts. (C) 2011 American Institute of Physics. [doi:10.1063/1.3622145] C1 [Simpkins, B. S.; Pehrsson, P. E.] USN, Res Lab, Div Chem, Washington, DC 20375 USA. [Mastro, M. A.; Eddy, C. R., Jr.; Hite, J. K.] USN, Res Lab, Div Elect Sci & Technol, Washington, DC 20375 USA. RP Simpkins, BS (reprint author), USN, Res Lab, Div Chem, Washington, DC 20375 USA. EM blake.simpkins@nrl.navy.mil RI Hite, Jennifer/L-5637-2015 OI Hite, Jennifer/0000-0002-4090-0826 FU Office of Naval Research (ONR) FX The authors acknowledge support from the Office of Naval Research (ONR) and thank J. Caldwell and T. Anderson for experimental assistance and J. Ahn, B.-J. Kim, and J. Kim for TEM imaging. NR 22 TC 7 Z9 8 U1 1 U2 16 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0021-8979 J9 J APPL PHYS JI J. Appl. Phys. PD AUG 15 PY 2011 VL 110 IS 4 AR 044303 DI 10.1063/1.3622145 PG 4 WC Physics, Applied SC Physics GA 814VC UT WOS:000294484300130 ER PT J AU Kulkarni, H Okulicz, JF Grandits, G Crum-Cianflone, NF Landrum, ML Hale, B Wortmann, G Tramont, E Polis, M Dolan, M Lifson, AR Agan, BK Ahuja, SK Marconi, VC AF Kulkarni, Hemant Okulicz, Jason F. Grandits, Greg Crum-Cianflone, Nancy F. Landrum, Michael L. Hale, Braden Wortmann, Glenn Tramont, Edmund Polis, Michael Dolan, Matthew Lifson, Alan R. Agan, Brian K. Ahuja, Sunil K. Marconi, Vincent C. TI Early Postseroconversion CD4 Cell Counts Independently Predict CD4 Cell Count Recovery in HIV-1-Postive Subjects Receiving Antiretroviral Therapy SO JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES LA English DT Article DE CD4 count; highly active antiretroviral therapy; outcomes; predictors; treatment response ID PLASMA HIV RNA; VIROLOGICAL RESPONSES; HIV-1-INFECTED PATIENTS; IMMUNOLOGICAL RESPONSE; DISEASE PROGRESSION; PROTEASE INHIBITOR; INFECTED PATIENTS; IMMUNODEFICIENCY; SUPPRESSION; INTERRUPTION AB Background: The relationship between CD4(+) T-cell counts determined soon after seroconversion with HIV-1 (baseline CD4), nadir CD4, and CD4 levels attained during highly active antiretroviral therapy (HAART) is unknown. Methods: Longitudinal, including baseline (at or soon after HIV diagnosis), intermediate (nadir), and distal (post-HAART) CD4(+) T-cell counts were assessed in 1085 seroconverting subjects who achieved viral load suppression from a large well-characterized cohort. The association of baseline with post-HAART CD4(+) T-cell count was determined after adjustment for other relevant covariates. Results: A higher baseline CD4(+) T-cell count predicted a greater postHAART CD4(+) T-cell count, independent of the nadir and other explanatory variables. Together, baseline and nadir strongly predicted the post-HAART CD4(+) count such that a high baseline and lower nadir were associated with a maximal immune recovery after HAART. Likelihood of recovery of the baseline count after HAART was significantly higher when the nadir/ baseline count ratio was consistently >= 0.6. Conclusions: Among viral load suppressing seroconverters, the absolute CD4(+) T-cell count attained post-HAART is highly dependent on both baseline and nadir CD4(+) T-cell counts. These associations further support the early diagnosis and initiation of HAART among HIV-infected persons. C1 [Kulkarni, Hemant; Ahuja, Sunil K.] S Texas Vet Hlth Care Syst, Vet Adm Res Ctr AIDS & HIV Infect 1, San Antonio, TX USA. [Kulkarni, Hemant; Ahuja, Sunil K.] Univ Texas Hlth Sci Ctr San Antonio, Dept Med, San Antonio, TX 78229 USA. [Okulicz, Jason F.; Grandits, Greg; Crum-Cianflone, Nancy F.; Landrum, Michael L.; Hale, Braden; Wortmann, Glenn; Tramont, Edmund; Polis, Michael; Agan, Brian K.; Marconi, Vincent C.] Uniformed Serv Univ Hlth Sci, Infect Dis Clin Res Program, Bethesda, MD 20814 USA. [Okulicz, Jason F.; Landrum, Michael L.] Brooke Army Med Ctr, San Antonio Mil Med Ctr, Infect Dis Serv, Ft Sam Houston, TX 78234 USA. [Grandits, Greg] Univ Minnesota, Div Biostat, Minneapolis, MN USA. [Crum-Cianflone, Nancy F.; Hale, Braden] USN, Infect Dis Clin, San Diego Med Ctr, San Diego, CA 92152 USA. [Wortmann, Glenn] Walter Reed Army Med Ctr, Infect Dis Serv, Washington, DC 20307 USA. [Tramont, Edmund; Polis, Michael] NIAID, NIH, Bethesda, MD 20892 USA. [Dolan, Matthew] Wilford Hall USAF Med Ctr, Henry M Jackson Fdn, Lackland AFB, TX 78236 USA. [Lifson, Alan R.] Univ Minnesota, Div Epidemiol & Community Hlth, Minneapolis, MN USA. [Ahuja, Sunil K.] Univ Texas Hlth Sci Ctr San Antonio, Dept Microbiol & Immunol & Biochem, San Antonio, TX 78229 USA. [Marconi, Vincent C.] Emory Univ, Sch Med, Dept Med, Div Infect Dis, Atlanta, GA USA. RP Kulkarni, H (reprint author), 12023 Waterway Rdg, San Antonio, TX USA. EM kulkarnih@uthscsa.edu RI Marconi, Vincent/N-3210-2014; OI Marconi, Vincent/0000-0001-8409-4689; Polis, Michael/0000-0002-9151-2268; Agan, Brian/0000-0002-5114-1669 FU Infectious Disease Clinical Research Program (IDCRP) [IDCRP-000-03]; Department of Defense; National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH) [Y1-AI-5072]; Veterans Administration Center on AIDS and HIV infection of the South Texas Veterans Health Care System; NIH [R37046326]; VA MERIT award; Elizabeth Glaser Scientist Award; Burroughs Wellcome Clinical Scientist Award in Translational Research; Doris Duke Distinguished Clinical Scientist Award FX Support for this work (IDCRP-000-03) was provided by the Infectious Disease Clinical Research Program (IDCRP), a Department of Defense program executed through the Uniformed Services University of the Health Sciences. This project has been funded in whole, or in part, with federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), under Inter-Agency Agreement Y1-AI-5072. This work was also supported by the Veterans Administration Center on AIDS and HIV infection of the South Texas Veterans Health Care System, and a MERIT (R37046326) award from the NIH to S. K. A. S. K. A. is also supported by a VA MERIT award and is a recipient of the Elizabeth Glaser Scientist Award, the Burroughs Wellcome Clinical Scientist Award in Translational Research, and the Doris Duke Distinguished Clinical Scientist Award. The content of this publication is the sole responsibility of the authors and does not necessarily reflect the views or policies of the NIH or the Department of Health and Human Services, the Department of Defense or the Departments of the Army, Navy or Air Force. Mention of trade names, commercial products, or organizations does not imply endorsement by the US Government. NR 45 TC 9 Z9 9 U1 0 U2 2 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 1525-4135 J9 JAIDS-J ACQ IMM DEF JI JAIDS PD AUG 15 PY 2011 VL 57 IS 5 BP 387 EP 395 DI 10.1097/QAI.0b013e3182219113 PG 9 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA 800RE UT WOS:000293381300013 PM 21546844 ER PT J AU Krantz, EM Hullsiek, KH Okulicz, JF Weintrob, AC Agan, BK Crum-Cianflone, NF Ganesan, A Ferguson, TM Hale, BR AF Krantz, Elizabeth M. Hullsiek, Katherine Huppler Okulicz, Jason F. Weintrob, Amy C. Agan, Brian K. Crum-Cianflone, Nancy F. Ganesan, Anuradha Ferguson, Tomas M. Hale, Braden R. CA Infect Dis Clin Res Program HIV TI Elevated CD8 Counts During HAART Are Associated With HIV Virologic Treatment Failure SO JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES LA English DT Article DE human immunodeficiency virus; CD8 count; antiretroviral therapy; HIV viral load suppression; HIV virologic failure ID ACTIVE ANTIRETROVIRAL THERAPY; IMMUNE ACTIVATION MARKERS; T-CELL-ACTIVATION; HIV-1-INFECTED PATIENTS; CD38 EXPRESSION; PROTEASE INHIBITOR; PROGNOSTIC VALUE; INFECTED INDIVIDUALS; DISEASE PROGRESSION; VIRAL REPLICATION AB Objective: To evaluate whether elevated CD8 counts are associated with increased risk of virologic treatment failure in HIV-infected individuals. Design: Retrospective cohort study. Methods: US Military HIV Natural History Study participants who initiated highly active antiretroviral therapy (HAART) in 1996-2008 had 6- and 12-month post-HAART HIV RNA <400 copies per milliliter, >= 2 subsequent HIV viral loads and a baseline CD8 count were eligible (n = 817). Baseline was 12 months after the start of HAART, virologic failure (VF) was defined as confirmed HIV RNA >= 400 copies per milliliter, and CD8 counts >= 1200 cells per cubic millimeter were considered elevated. Cox models were used to examine the effect of baseline and time-updated CD8 counts on VF. Results: There were 216 failures for a rate of 5.6 per 100 person-years [95% confidence interval (CI): 4.9 to 6.4]. Among those initiating HAART in 2000-2008, the participants with elevated baseline CD8 counts had significantly greater risk of VF compared with those with baseline CD8 counts <= 600 cells per cubic millimeter [hazard ratio (HR) = 2.68, 95% CI: 1.13 to 6.35]. The participants with elevated CD8 counts at >20% of previous 6-month follow-up visits had a greater risk of failure at the current visit than those who did not (HR = 1.53, 95% CI: 1.14 to 2.06). Those with CD8 counts that increased after the start of HAART had a greater risk of failure than those with CD8 counts that decreased or remained the same (HR = 1.59, 95% CI: 1.19 to 2.13). Conclusions: Initial or serial elevated CD8 counts while on HAART or an increase in CD8 counts from HAART initiation may be early warnings for future treatment failure. C1 [Hale, Braden R.] USN, Hlth Res Ctr, San Diego, CA 92106 USA. [Krantz, Elizabeth M.; Hullsiek, Katherine Huppler; Okulicz, Jason F.; Weintrob, Amy C.; Agan, Brian K.; Crum-Cianflone, Nancy F.; Ganesan, Anuradha; Ferguson, Tomas M.; Infect Dis Clin Res Program HIV] Uniformed Serv Univ Hlth Sci, Infect Dis Clin Res Program, Bethesda, MD 20814 USA. [Krantz, Elizabeth M.; Hullsiek, Katherine Huppler] Univ Minnesota, Div Biostat, Minneapolis, MN USA. [Okulicz, Jason F.] San Antonio Mil Med Ctr, Infect Dis Serv, Ft Sam Houston, TX USA. [Weintrob, Amy C.] Walter Reed Army Med Ctr, Infect Dis Serv, Washington, DC 20307 USA. [Crum-Cianflone, Nancy F.] USN, Infect Dis Clin, San Diego Med Ctr, San Diego, CA 92152 USA. [Ganesan, Anuradha] Natl Naval Med Ctr, Infect Dis Clin, Bethesda, MD USA. [Ferguson, Tomas M.] Tripler Army Med Ctr, Infect Dis Serv, Honolulu, HI 96859 USA. RP Hale, BR (reprint author), USN, Hlth Res Ctr, Code 165,140 Sylvester Rd, San Diego, CA 92106 USA. EM Braden.Hale@med.navy.mil OI Agan, Brian/0000-0002-5114-1669 FU Infectious Disease Clinical Research Program (IDCRP) [IDCRP-000-19]; Department of Defense; National Institute of Allergy and Infectious Diseases, National Institutes of Health [Y1-AI-5072] FX Supported by the Infectious Disease Clinical Research Program (IDCRP; IDCRP-000-19), a Department of Defense program executed through the Uniformed Services University of the Health Sciences. This project has been funded in whole, or in part, with federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, under Inter-Agency Agreement Y1-AI-5072. NR 58 TC 9 Z9 9 U1 0 U2 1 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 1525-4135 J9 JAIDS-J ACQ IMM DEF JI JAIDS PD AUG 15 PY 2011 VL 57 IS 5 BP 396 EP 403 DI 10.1097/QAI.0b013e318221c62a PG 8 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA 800RE UT WOS:000293381300014 PM 21602694 ER PT J AU Ajello, M Atwood, WB Baldini, L Barbiellini, G Bastieri, D Bellazzini, R Berenji, B Blandford, RD Bloom, ED Bonamente, E Borgland, AW Bottacini, E Bouvier, A Bregeon, J Brigida, M Bruel, P Buehler, R Buson, S Caliandro, GA Cameron, RA Caraveo, PA Cecchi, C Charles, E Chekhtman, A Ciprini, S Claus, R Cohen-Tanugi, J Cutini, S de Angelis, A de Palma, F Dermer, CD Digel, SW Silva, EDE Drell, PS Favuzzi, C Fegan, SJ Focke, WB Fukazawa, Y Fusco, P Gargano, F Gehrels, N Germani, S Giglietto, N Giordano, F Giroletti, M Glanzman, T Godfrey, G Grenier, IA Guiriec, S Gustafsson, M Hadasch, D Iafrate, G Johannesson, G Johnson, AS Kamae, T Katagiri, H Kataoka, J Kuss, M Latronico, L Lionetto, AM Longo, F Loparco, F Lovellette, MN Lubrano, P Mazziotta, MN McEnery, JE Michelson, PF Mizuno, T Monte, C Monzani, ME Morselli, A Moskalenko, IV Murgia, S Naumann-Godo, M Norris, JP Nuss, E Ohsugi, T Omodei, N Orlando, E Ormes, JF Ozaki, M Paneque, D Panetta, JH Pesce-Rollins, M Pierbattista, M Piron, F Raino, S Rando, R Razzano, M Reimer, A Reimer, O Ritz, S Schalk, TL Sgro, C Siegal-Gaskins, J Siskind, EJ Smith, PD Spandre, G Spinelli, P Suson, DJ Takahashi, H Tanaka, T Thayer, JG Thayer, JB Tibaldo, L Tosti, G Troja, E Usher, TL Vandenbroucke, J Vasileiou, V Vianello, G Vilchez, N Waite, AP Wang, P Winer, BL Wood, KS Yang, Z Zimmer, S AF Ajello, M. Atwood, W. B. Baldini, L. Barbiellini, G. Bastieri, D. Bellazzini, R. Berenji, B. Blandford, R. D. Bloom, E. D. Bonamente, E. Borgland, A. W. Bottacini, E. Bouvier, A. Bregeon, J. Brigida, M. Bruel, P. Buehler, R. Buson, S. Caliandro, G. A. Cameron, R. A. Caraveo, P. A. Cecchi, C. Charles, E. Chekhtman, A. Ciprini, S. Claus, R. Cohen-Tanugi, J. Cutini, S. de Angelis, A. de Palma, F. Dermer, C. D. Digel, S. W. Silva, E. do Couto e Drell, P. S. Favuzzi, C. Fegan, S. J. Focke, W. B. Fukazawa, Y. Fusco, P. Gargano, F. Gehrels, N. Germani, S. Giglietto, N. Giordano, F. Giroletti, M. Glanzman, T. Godfrey, G. Grenier, I. A. Guiriec, S. Gustafsson, M. Hadasch, D. Iafrate, G. Johannesson, G. Johnson, A. S. Kamae, T. Katagiri, H. Kataoka, J. Kuss, M. Latronico, L. Lionetto, A. M. Longo, F. Loparco, F. Lovellette, M. N. Lubrano, P. Mazziotta, M. N. McEnery, J. E. Michelson, P. F. Mizuno, T. Monte, C. Monzani, M. E. Morselli, A. Moskalenko, I. V. Murgia, S. Naumann-Godo, M. Norris, J. P. Nuss, E. Ohsugi, T. Omodei, N. Orlando, E. Ormes, J. F. Ozaki, M. Paneque, D. Panetta, J. H. Pesce-Rollins, M. Pierbattista, M. Piron, F. Raino, S. Rando, R. Razzano, M. Reimer, A. Reimer, O. Ritz, S. Schalk, T. L. Sgro, C. Siegal-Gaskins, J. Siskind, E. J. Smith, P. D. Spandre, G. Spinelli, P. Suson, D. J. Takahashi, H. Tanaka, T. Thayer, J. G. Thayer, J. B. Tibaldo, L. Tosti, G. Troja, E. Usher, T. L. Vandenbroucke, J. Vasileiou, V. Vianello, G. Vilchez, N. Waite, A. P. Wang, P. Winer, B. L. Wood, K. S. Yang, Z. Zimmer, S. CA Fermi LAT Collaboration TI Constraints on dark matter models from a Fermi LAT search for high-energy cosmic-ray electrons from the Sun SO PHYSICAL REVIEW D LA English DT Article ID LARGE-AREA TELESCOPE; DAMA/LIBRA; EMISSION AB During its first year of data taking, the Large Area Telescope (LAT) onboard the Fermi Gamma-Ray Space Telescope has collected a large sample of high-energy cosmic-ray electrons and positrons (CREs). We present the results of a directional analysis of the CRE events, in which we searched for a flux excess correlated with the direction of the Sun. Two different and complementary analysis approaches were implemented, and neither yielded evidence of a significant CRE flux excess from the Sun. We derive upper limits on the CRE flux from the Sun's direction, and use these bounds to constrain two classes of dark matter models which predict a solar CRE flux: (1) models in which dark matter annihilates to CREs via a light intermediate state, and (2) inelastic dark matter models in which dark matter annihilates to CREs. C1 [Ajello, M.; Berenji, B.; Blandford, R. D.; Bloom, E. D.; Borgland, A. W.; Bottacini, E.; Buehler, R.; Cameron, R. A.; Charles, E.; Claus, R.; Digel, S. W.; Silva, E. do Couto e; Drell, P. S.; Focke, W. B.; Glanzman, T.; Godfrey, G.; Johnson, A. S.; Kamae, T.; Michelson, P. F.; Monzani, M. E.; Moskalenko, I. V.; Murgia, S.; Omodei, N.; Orlando, E.; Paneque, D.; Panetta, J. H.; Reimer, A.; Reimer, O.; Tanaka, T.; Thayer, J. G.; Thayer, J. B.; Usher, T. L.; Vandenbroucke, J.; Vianello, G.; Waite, A. P.; Wang, P.] Stanford Univ, Dept Phys, Kavli Inst Particle Astrophys & Cosmol, WW Hansen Expt Phys Lab, Stanford, CA 94305 USA. [Ajello, M.; Berenji, B.; Blandford, R. D.; Bloom, E. D.; Borgland, A. W.; Bottacini, E.; Buehler, R.; Cameron, R. A.; Charles, E.; Claus, R.; Digel, S. W.; Silva, E. do Couto e; Drell, P. S.; Focke, W. B.; Glanzman, T.; Godfrey, G.; Johnson, A. S.; Kamae, T.; Michelson, P. F.; Monzani, M. E.; Moskalenko, I. V.; Murgia, S.; Omodei, N.; Orlando, E.; Paneque, D.; Panetta, J. H.; Reimer, A.; Reimer, O.; Tanaka, T.; Thayer, J. G.; Thayer, J. B.; Usher, T. L.; Vandenbroucke, J.; Vianello, G.; Waite, A. P.; Wang, P.] Stanford Univ, SLAC Natl Accelerator Lab, Stanford, CA 94305 USA. [Atwood, W. B.; Bouvier, A.; Ritz, S.; Schalk, T. L.] Univ Calif Santa Cruz, Dept Phys, Santa Cruz Inst Particle Phys, Santa Cruz, CA 95064 USA. [Atwood, W. B.; Bouvier, A.; Ritz, S.; Schalk, T. L.] Univ Calif Santa Cruz, Dept Astron & Astrophys, Santa Cruz, CA 95064 USA. [Baldini, L.; Bellazzini, R.; Bregeon, J.; Kuss, M.; Latronico, L.; Pesce-Rollins, M.; Razzano, M.; Sgro, C.; Spandre, G.] Ist Nazl Fis Nucl, Sez Pisa, I-56127 Pisa, Italy. [Barbiellini, G.; Iafrate, G.; Longo, F.] Ist Nazl Fis Nucl, Sez Trieste, I-34127 Trieste, Italy. [Barbiellini, G.; Longo, F.] Univ Trieste, Dipartimento Fis, I-34127 Trieste, Italy. [Bastieri, D.; Buson, S.; Gustafsson, M.; Rando, R.; Tibaldo, L.] Ist Nazl Fis Nucl, Sez Padova, I-35131 Padua, Italy. [Bastieri, D.; Buson, S.; Rando, R.; Tibaldo, L.] Univ Padua, Dipartimento Fis G Galilei, I-35131 Padua, Italy. [Bonamente, E.; Cecchi, C.; Germani, S.; Lubrano, P.; Tosti, G.] Ist Nazl Fis Nucl, Sez Perugia, I-06123 Perugia, Italy. [Bonamente, E.; Cecchi, C.; Ciprini, S.; Germani, S.; Lubrano, P.; Tosti, G.] Univ Perugia, Dipartimento Fis, I-06123 Perugia, Italy. [Brigida, M.; de Palma, F.; Favuzzi, C.; Fusco, P.; Giglietto, N.; Giordano, F.; Loparco, F.; Monte, C.; Raino, S.; Spinelli, P.] Univ Bari, Dipartimento Fis M Merlin, I-70126 Bari, Italy. [Brigida, M.; de Palma, F.; Favuzzi, C.; Fusco, P.; Giglietto, N.; Giordano, F.; Loparco, F.; Monte, C.; Raino, S.; Spinelli, P.] Politecn Bari, Dipartimento Fis M Merlin, I-70126 Bari, Italy. [Brigida, M.; de Palma, F.; Favuzzi, C.; Fusco, P.; Gargano, F.; Giglietto, N.; Giordano, F.; Loparco, F.; Mazziotta, M. N.; Monte, C.; Raino, S.; Spinelli, P.] Ist Nazl Fis Nucl, Sez Bari, I-70126 Bari, Italy. [Bruel, P.; Fegan, S. J.] Ecole Polytech, CNRS, IN2P3, Lab Leprince Ringuet, F-91128 Palaiseau, France. [Caliandro, G. A.; Hadasch, D.] CSIC, IEEE, Inst Ciencies Espai, Barcelona 08193, Spain. [Caraveo, P. A.] INAF Ist Astrofis Spaziale & Fis Cosm, I-20133 Milan, Italy. [Chekhtman, A.] Artep Inc, Ellicott City, MD 21042 USA. [Ciprini, S.; Cutini, S.] ASI Sci Data Ctr, I-00044 Rome, Italy. [Cohen-Tanugi, J.; Nuss, E.; Piron, F.; Vasileiou, V.] Univ Montpellier 2, CNRS, IN2P3, Lab Univers & Particules Montpellier, Montpellier, France. [de Angelis, A.] Univ Udine, Dipartimento Fis, I-33100 Udine, Italy. [de Angelis, A.] Ist Nazl Fis Nucl, Sez Trieste, Grp Coll Udine, I-33100 Udine, Italy. [Dermer, C. D.; Lovellette, M. N.; Wood, K. S.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. [Fukazawa, Y.; Mizuno, T.] Hiroshima Univ, Dept Phys Sci, Hiroshima 7398526, Japan. [Gehrels, N.; McEnery, J. E.; Troja, E.] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA. [Giroletti, M.] INAF Ist Radioastron, I-40129 Bologna, Italy. [Grenier, I. A.; Naumann-Godo, M.; Pierbattista, M.; Tibaldo, L.] Univ Paris Diderot, CEA Saclay, CEA IRFU, CNRS,Serv Astrophys,Lab AIM, F-91191 Gif Sur Yvette, France. [Guiriec, S.] Univ Alabama, CSPAR, Huntsville, AL 35899 USA. [Iafrate, G.] Ist Nazl Astrofis, Osservatorio Astron Trieste, I-34143 Trieste, Italy. [Johannesson, G.] Univ Iceland, Inst Sci, IS-107 Reykjavik, Iceland. [Katagiri, H.] Ibaraki Univ, Coll Sci, Mito, Ibaraki 3108512, Japan. [Kataoka, J.] Waseda Univ, Res Inst Sci & Engn, Shinjuku Ku, Tokyo 1698555, Japan. [Lionetto, A. M.; Morselli, A.] Ist Nazl Fis Nucl, Sez Roma Tor Vergata, I-00133 Rome, Italy. [Lionetto, A. M.] Univ Roma Tor Vergata, Dipartimento Fis, I-00133 Rome, Italy. [McEnery, J. E.] Univ Maryland, Dept Phys, College Pk, MD 20742 USA. [McEnery, J. E.] Univ Maryland, Dept Astron, College Pk, MD 20742 USA. [Norris, J. P.] Boise State Univ, Dept Phys, Boise, ID 83725 USA. [Ohsugi, T.; Takahashi, H.] Hiroshima Univ, Hiroshima Astrophys Sci Ctr, Hiroshima 7398526, Japan. [Orlando, E.] Max Planck Inst Extraterr Phys, D-85748 Garching, Germany. [Ormes, J. F.] Univ Denver, Dept Phys & Astron, Denver, CO 80208 USA. [Ozaki, M.] JAXA, Inst Space & Astronaut Sci, Chuo Ku, Kanagawa 2525210, Japan. [Paneque, D.] Max Planck Inst Phys & Astrophys, D-80805 Munich, Germany. [Reimer, A.; Reimer, O.] Leopold Franzens Univ Innsbruck, Inst Astro & Teilchenphys, A-6020 Innsbruck, Austria. [Reimer, A.; Reimer, O.] Leopold Franzens Univ Innsbruck, Inst Theoret Phys, A-6020 Innsbruck, Austria. [Siegal-Gaskins, J.; Smith, P. D.; Winer, B. L.] Ohio State Univ, Ctr Cosmol & Astroparticle Phys, Dept Phys, Columbus, OH 43210 USA. [Siskind, E. J.] NYCB Real Time Comp Inc, Lattingtown, NY 11560 USA. [Suson, D. J.] Purdue Univ Calumet, Dept Chem & Phys, Hammond, IN 46323 USA. [Vianello, G.] CIFS, I-10133 Turin, Italy. [Vilchez, N.] IRAP, CNRS, F-31028 Toulouse 4, France. [Vilchez, N.] Univ Toulouse, UPS OMP, IRAP, Toulouse, France. [Troja, E.] NASA, Washington, DC USA. [Yang, Z.; Zimmer, S.] Stockholm Univ, Dept Phys, AlbaNova, SE-10691 Stockholm, Sweden. [Yang, Z.; Zimmer, S.] AlbaNova, Oskar Klein Ctr Cosmoparticle Phys, SE-10691 Stockholm, Sweden. RP Ajello, M (reprint author), Stanford Univ, Dept Phys, Kavli Inst Particle Astrophys & Cosmol, WW Hansen Expt Phys Lab, Stanford, CA 94305 USA. EM loparco@ba.infn.it; mazziotta@ba.infn.it; jsg@mps.ohio-state.edu RI Moskalenko, Igor/A-1301-2007; Mazziotta, Mario /O-8867-2015; Sgro, Carmelo/K-3395-2016; Orlando, E/R-5594-2016; Morselli, Aldo/G-6769-2011; Gehrels, Neil/D-2971-2012; Johannesson, Gudlaugur/O-8741-2015; Gargano, Fabio/O-8934-2015; McEnery, Julie/D-6612-2012; Baldini, Luca/E-5396-2012; lubrano, pasquale/F-7269-2012; Kuss, Michael/H-8959-2012; giglietto, nicola/I-8951-2012; Reimer, Olaf/A-3117-2013; Tosti, Gino/E-9976-2013; Ozaki, Masanobu/K-1165-2013; Rando, Riccardo/M-7179-2013; Loparco, Francesco/O-8847-2015 OI Pesce-Rollins, Melissa/0000-0003-1790-8018; Giroletti, Marcello/0000-0002-8657-8852; Cutini, Sara/0000-0002-1271-2924; Berenji, Bijan/0000-0002-4551-772X; Baldini, Luca/0000-0002-9785-7726; Moskalenko, Igor/0000-0001-6141-458X; Mazziotta, Mario /0000-0001-9325-4672; Giordano, Francesco/0000-0002-8651-2394; De Angelis, Alessandro/0000-0002-3288-2517; Iafrate, Giulia/0000-0002-6185-8292; Caraveo, Patrizia/0000-0003-2478-8018; Sgro', Carmelo/0000-0001-5676-6214; SPINELLI, Paolo/0000-0001-6688-8864; Rando, Riccardo/0000-0001-6992-818X; Bastieri, Denis/0000-0002-6954-8862; Omodei, Nicola/0000-0002-5448-7577; Morselli, Aldo/0000-0002-7704-9553; Johannesson, Gudlaugur/0000-0003-1458-7036; Gargano, Fabio/0000-0002-5055-6395; lubrano, pasquale/0000-0003-0221-4806; giglietto, nicola/0000-0002-9021-2888; Reimer, Olaf/0000-0001-6953-1385; Loparco, Francesco/0000-0002-1173-5673 NR 45 TC 13 Z9 13 U1 0 U2 3 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 2470-0010 EI 2470-0029 J9 PHYS REV D JI Phys. Rev. D PD AUG 15 PY 2011 VL 84 IS 3 AR 032007 DI 10.1103/PhysRevD.84.032007 PG 17 WC Astronomy & Astrophysics; Physics, Particles & Fields SC Astronomy & Astrophysics; Physics GA 806VQ UT WOS:000293844100001 ER PT J AU Mott, PH Twigg, JN Roland, CM Nugent, KE Hogan, TE Robertson, CG AF Mott, Peter H. Twigg, Jeffrey N. Roland, C. Michael Nugent, Kenneth E. Hogan, Terry E. Robertson, Christopher G. TI Comparison of the Transient Stress-Strain Response of Rubber to Its Linear Dynamic Behavior SO JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS LA English DT Article DE high strain rate; linear dynamic; mechanical properties; stress-strain behavior ID VISCOELASTIC CONSTITUTIVE MODELS; COX-MERZ RULE; TEMPERATURE-DEPENDENCE; THERMORHEOLOGICAL COMPLEXITY; ATACTIC POLYPROPYLENE; POLYMER MELTS; RELAXATION; ELASTOMERS; POLYUREA; RATES AB Master curves of the small strain and dynamic shear modulus are compared with the transient mechanical response of rubbers stretched at ambient temperature over a seven-decade range of strain rates (10(-4) to 10(3) s(-1)). The experiments were carried out on 1,4- and 1,2-polybutadienes and a styrene-butadiene copolymer. These rubbers have respective glass transition temperatures, T-g, equal to -93.0, 0.5, and 4.1 degrees C, so that the room temperature measurements probed the rubbery plateau, the glass transition zone, and the onset of the glassy state. For the 1,4-polybutadiene, in accord with previous results, strain and strain rate effects were decoupled (additive). For the other two materials, encroachment of the segmental dynamics precluded separation of the effects of strain and rate. These results show that for rubbery polymers near Tg the use of linear dynamic data to predict stresses, strain energies, and other mechanical properties at higher strain rates entails large error. For example, the strain rate associated with an upturn in the modulus due to onset of the glass transition was three orders of magnitude higher for large tensile strains than for linear oscillatory shear strains. (C) 2011 Wiley Periodicals, Inc.* J Polym Sci Part B: Polym Phys 49: 1195-1202, 2011 C1 [Mott, Peter H.; Twigg, Jeffrey N.; Roland, C. Michael] USN, Res Lab, Div Chem, Washington, DC 20375 USA. [Nugent, Kenneth E.] Sci Applicat Int Corp, La Plata, MD 20646 USA. [Hogan, Terry E.; Robertson, Christopher G.] Bridgestone Amer, Ctr Res & Technol, Akron, OH 44317 USA. RP Mott, PH (reprint author), USN, Res Lab, Div Chem, Washington, DC 20375 USA. EM peter.mott@nrl.navy.mil RI Robertson, Christopher/J-1812-2012 OI Robertson, Christopher/0000-0002-4217-5429 FU Office of Naval Research [331, N0001410WX21721] FX This work was supported by the Office of Naval Research, in part by Code 331, Contract Number N0001410WX21721. NR 54 TC 1 Z9 1 U1 2 U2 21 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 0887-6266 J9 J POLYM SCI POL PHYS JI J. Polym. Sci. Pt. B-Polym. Phys. PD AUG 15 PY 2011 VL 49 IS 16 BP 1195 EP 1202 DI 10.1002/polb.22292 PG 8 WC Polymer Science SC Polymer Science GA 806VI UT WOS:000293843000006 ER PT J AU Huang, LL Massa, L AF Huang, Lulu Massa, Lou TI Kernel Energy Method Applied to an Energetic Nitrate Ester SO INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY LA English DT Article DE quantum mechanics; BSSE; explosive parameters; nitrogroups; HMX ID TDA1; RNA AB A recent synthesis results in a nitrate ester explosive C6N6O16H8 (Hisk75), composed of four nitrate ester groups (ONO2) and two nitro groups (NO2), with the property of being solid at room temperature with a low-melting point allowing the convenience of poured mold casting (Chavez et al., Angew Chem Int Ed 2008, 47, 8307). Using the crystal geometry, we have calculated the quantum chemical interaction energies, including basis set superposition errors between nearest neighboring molecules. Using quantum mechanics and the computer program CHEETA, we have calculated the explosive parameters of this new molecule, comparing to those of HMX, corroborating previous estimates of these same parameters. Calculations confirm this compound to be one of the best performing high-energy/high-density explosives. (C) 2010 Wiley Periodicals, Inc. Int J Quantum Chem 111: 2180-2186, 2011 C1 [Huang, Lulu] USN, Res Lab, Struct Matter Lab, Washington, DC 20375 USA. [Massa, Lou] CUNY Hunter Coll, New York, NY 10065 USA. [Massa, Lou] CUNY, Grad Sch, New York, NY 10065 USA. RP Huang, LL (reprint author), USN, Res Lab, Struct Matter Lab, Washington, DC 20375 USA. EM huang@nrl.navy.mil FU CUNY PSC [68518-0037, 69701-0038] FX Contract grant sponsor: CUNY PSC Faculty Grants Program.; Contract grant numbers: 68518-0037, 69701-0038. NR 17 TC 5 Z9 6 U1 2 U2 7 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 0020-7608 J9 INT J QUANTUM CHEM JI Int. J. Quantum Chem. PD AUG 15 PY 2011 VL 111 IS 10 BP 2180 EP 2186 DI 10.1002/qua.22503 PG 7 WC Chemistry, Physical; Mathematics, Interdisciplinary Applications; Physics, Atomic, Molecular & Chemical SC Chemistry; Mathematics; Physics GA 756EK UT WOS:000289994300002 ER PT J AU Zhou, XY Yin, YJ Wang, ZD Zhou, JJ Huang, H Mansour, AN Zaykoski, JA Fedderly, JJ Balizer, E AF Zhou, Xiangyang Yin, Yijing Wang, Zedong Zhou, Juanjuan Huang, Hao Mansour, Azzam N. Zaykoski, James A. Fedderly, Jeffry J. Balizer, Edward TI Effect of hot pressing on the ionic conductivity of the PEO/LiCF3SO3 based electrolyte membranes SO SOLID STATE IONICS LA English DT Article ID COMPOSITE POLYMER ELECTROLYTES; ALKALI-METAL SALTS; POLYPHOSPHAZENE MEMBRANES; HYDROGEL ELECTROLYTE; TRANSPORT-PROPERTIES; FUEL-CELLS; CRYSTALLIZATION; POTENTIALS; MICROSCOPY; BATTERIES AB PEO/LiCF3SO3 (LiTFS) /Ethylene carbonate (EC) polymer electrolyte membranes were prepared with a solution casting method followed by a hot pressing process. The effect of the hot pressing process on the in-plane conductivity of the PEO electrolyte membranes was evaluated using a four-electrode AC impedance method. The composition, morphology, and microstructure of the composite polymer electrolyte were characterized using scanning electron microscopy (SEM). Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and differential scanning calorimetry (DSc). The AC impedance measurement results indicate that the hot pressing process can increase the room temperature conductivity of the membranes 14 times to 1.7 x 10(-3) S cm(-1) depending upon the duration of the hot pressing process. The SEM, FTIR, XRD, and DSC results indicate that the hot pressing process could increase the amorphous part of the polymer electrolyte membrane or convert large spherulite crystals into nano-sized crystals. Published by Elsevier B.V. C1 [Zhou, Xiangyang; Yin, Yijing; Wang, Zedong; Zhou, Juanjuan; Huang, Hao] Univ Miami, Dept Mech & Aerosp Engn, Coral Gables, FL 33124 USA. [Mansour, Azzam N.; Zaykoski, James A.; Fedderly, Jeffry J.; Balizer, Edward] NSWC, Carderock Div, Syst & Mat Power & Protect Branch, Bethesda, MD 20817 USA. RP Zhou, XY (reprint author), Univ Miami, Dept Mech & Aerosp Engn, 16 Mem Dr, Coral Gables, FL 33124 USA. EM xzhou@miami.edu FU Office of Naval Research (ONR) [N00014-08-1-0332, N00014-08-WX-20797] FX The authors would like to thank the Office of Naval Research (ONR) for financial support under award numbers N00014-08-1-0332 and N00014-08-WX-20797. NR 41 TC 17 Z9 17 U1 2 U2 8 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0167-2738 J9 SOLID STATE IONICS JI Solid State Ion. PD AUG 11 PY 2011 VL 196 IS 1 BP 18 EP 24 DI 10.1016/j.ssi.2011.05.018 PG 7 WC Chemistry, Physical; Physics, Condensed Matter SC Chemistry; Physics GA 825VW UT WOS:000295311200003 ER PT J AU Porter, CK Riddle, MS Tribble, DR Bougeois, AL McKenzie, R Isidean, SD Sebeny, P Savarino, SJ AF Porter, Chad K. Riddle, Mark S. Tribble, David R. Bougeois, A. Louis McKenzie, Robin Isidean, Sandra D. Sebeny, Peter Savarino, Stephen J. TI A systematic review of experimental infections with enterotoxigenic Escherichia coli (ETEC) SO VACCINE LA English DT Review DE Enterotoxigenic Escherichia coli; Challenge; Clinical trial ID COLONIZATION FACTOR ANTIGEN; IRRITABLE-BOWEL-SYNDROME; HEAT-STABLE ENTEROTOXIN; STATES MILITARY PERSONNEL; TRAVELERS DIARRHEA; BISMUTH SUBSALICYLATE; DOUBLE-BLIND; TRIMETHOPRIM-SULFAMETHOXAZOLE; CLINICAL-FEATURES; MOLECULAR CHARACTERIZATION AB Volunteer challenge with enterotoxigenic Escherichia coli (ETEC) has been used for four decades to elucidate the pathogenesis and immune responses and assess efficacy of various interventions. We performed a systematic review of these studies and a meta-analysis of individual patient-level data (IPD) from a subset of studies using standard methodology. We identified 27 studies of 11 ETEC strains administered to 443 naive subjects at doses from 1 x 10(6) to 1 x 10(10) colony forming units (cfu). Diarrhea attack rates varied by strain, dose and enterotoxin. Similar rates were seen at doses of 5 x 10(8) to 1 x 10(10) cfu with the three most commonly used strains B7A, E24377A, H10407. In IPD analysis, the highest diarrhea attack rates were seen with strains B7A, H10407 and E24377A. The H10407 induced significantly higher stool output than the other strains. Additionally, the rate of output was different across strains. The risk of diarrhea, abdominal cramps, nausea and headaches differed significantly by ETEC strain. An increased risk of nausea, abdominal cramps and headaches was seen for females. Baseline anti-LT IgG titers appeared to be associated with a decrease risk of diarrhea outcomes, a trend not seen with anti-LT IgA or seen consistently with anti-colonization factor antibodies. Neither early antibiotic treatment nor diarrhea duration significantly affected the frequency or magnitude of serologic responses. These studies have served as an invaluable tool in understanding disease course, pathogenicity, innate immune responses and an early assessment of product efficacy. When designing and planning experimental ETEC infection studies in this age of increased ethical scrutiny and growing appreciation of post-infectious sequelae, better understanding of available data is essential. Published by Elsevier Ltd. C1 [Porter, Chad K.; Riddle, Mark S.; Isidean, Sandra D.; Savarino, Stephen J.] USN, Med Res Ctr, Enter Dis Dept, Silver Spring, MD 20910 USA. [Tribble, David R.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA. [Bougeois, A. Louis; McKenzie, Robin] Johns Hopkins Univ, Baltimore, MD USA. [Sebeny, Peter] Naval Med Res Unit 3, Cairo, Egypt. RP Porter, CK (reprint author), USN, Med Res Ctr, Enter Dis Dept, Silver Spring, MD 20910 USA. EM chad.porter@med.navy.mil RI Riddle, Mark/A-8029-2011 NR 76 TC 22 Z9 22 U1 2 U2 12 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0264-410X J9 VACCINE JI Vaccine PD AUG 11 PY 2011 VL 29 IS 35 BP 5869 EP 5885 DI 10.1016/j.vaccine.2011.05.021 PG 17 WC Immunology; Medicine, Research & Experimental SC Immunology; Research & Experimental Medicine GA 810RX UT WOS:000294145900007 PM 21616116 ER PT J AU Wang, X Riley, MA Simpson, J Paul, ES Ollier, J Janssens, RVF Ayangeakaa, AD Boston, HC Carpenter, MP Chiara, CJ Garg, U Hartley, DJ Judson, DS Kondev, FG Lauritsen, T Lumley, NM Matta, J Nolan, PJ Petri, M Revill, JP Riedinger, LL Rigby, SV Unsworth, C Zhu, S Ragnarsson, I AF Wang, X. Riley, M. A. Simpson, J. Paul, E. S. Ollier, J. Janssens, R. V. F. Ayangeakaa, A. D. Boston, H. C. Carpenter, M. P. Chiara, C. J. Garg, U. Hartley, D. J. Judson, D. S. Kondev, F. G. Lauritsen, T. Lumley, N. M. Matta, J. Nolan, P. J. Petri, M. Revill, J. P. Riedinger, L. L. Rigby, S. V. Unsworth, C. Zhu, S. Ragnarsson, I. TI Quadrupole moments of collective structures up to spin similar to 65(h)over-bar in Er-157 and Er-158: A challenge for understanding triaxiality in nuclei SO PHYSICS LETTERS B LA English DT Article DE Ultrahigh-spin collective structures; Transition quadrupole moments; Cranked Nilsson-Strutinsky calculations; Triaxial nuclear shape ID BACKGROUND SUBTRACTION; LIFETIME MEASUREMENTS; SUPERDEFORMED BANDS; COINCIDENCE DATA; CRANKING MODEL; TERMINATIONS; EXCITATIONS; DY-152 AB The transition quadrupole moments. Q(t), of four weakly populated collective bands up to spin similar to 65h in Er-157,Er-158 have been measured to be similar to II eb demonstrating that these sequences are associated with large deformations. However, the data are inconsistent with calculated values from cranked Nilsson-Strutinsky calculations that predict the lowest energy triaxial shape to be associated with rotation about the short principal axis. The data appear to favor either a stable triaxial shape rotating about the intermediate axis or, alternatively, a triaxial shape with larger deformation rotating about the short axis. These new results challenge the present understanding of triaxiality in nuclei. (C) 2011 Elsevier B.V. All rights reserved. C1 [Wang, X.; Riley, M. A.] Florida State Univ, Dept Phys, Tallahassee, FL 32306 USA. [Simpson, J.; Ollier, J.] STFC Daresbury Lab, Warrington WA4 4AD, Cheshire, England. [Paul, E. S.; Boston, H. C.; Judson, D. S.; Nolan, P. J.; Revill, J. P.; Rigby, S. V.; Unsworth, C.] Univ Liverpool, Dept Phys, Liverpool L69 7ZE, Merseyside, England. [Janssens, R. V. F.; Carpenter, M. P.; Chiara, C. J.; Lauritsen, T.; Zhu, S.] Argonne Natl Lab, Div Phys, Argonne, IL 60439 USA. [Ayangeakaa, A. D.; Garg, U.; Matta, J.] Univ Notre Dame, Dept Phys, Notre Dame, IN 46556 USA. [Chiara, C. J.] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA. [Hartley, D. J.] USN Acad, Dept Phys, Annapolis, MD 21402 USA. [Kondev, F. G.] Argonne Natl Lab, Nucl Engn Div, Argonne, IL 60439 USA. [Lumley, N. M.] Univ Manchester, Schuster Lab, Manchester M13 9PL, Lancs, England. [Petri, M.] Univ Calif Berkeley, Lawrence Berkeley Lab, Div Nucl Sci, Berkeley, CA 94720 USA. [Riedinger, L. L.] Univ Tennessee, Dept Phys & Astron, Knoxville, TN 37996 USA. [Ragnarsson, I.] Lund Univ, LTH, Div Math Phys, SE-22100 Lund, Sweden. RP Wang, X (reprint author), Florida State Univ, Dept Phys, Tallahassee, FL 32306 USA. EM xwang3@nucmar.physics.fsu.edu RI Carpenter, Michael/E-4287-2015; Ayangeakaa, Akaa/F-3683-2015; Petri, Marina/H-4630-2016 OI Carpenter, Michael/0000-0002-3237-5734; Ayangeakaa, Akaa/0000-0003-1679-3175; Petri, Marina/0000-0002-3740-6106 FU U.S. National Science Foundation [PHY-0756474, PHY-0554762, PHY-0754674]; U.S. Department of Energy, Office of Nuclear Physics [DE-AC02-06CH11357, DE-FG02-94ER40834, DE-AC02-05CH11231, DE-FG02-96ER40983]; United Kingdom Science and Technology Facilities Council; Swedish Science Research Council; State of Florida FX The authors acknowledge Paul Morrall for preparing the targets, and the ATLAS operations staff for assistance. Discussions with S. Frauendorf and W. Nazarewicz are greatly appreciated. This work has been supported in part by the U.S. National Science Foundation under grants No. PHY-0756474 (FSU), PHY-0554762 (USNA), and PHY-0754674 (UND), the U.S. Department of Energy, Office of Nuclear Physics, under contracts No. DE-AC02-06CH11357 (ANL), DE-FG02-94ER40834 (UMD), DE-AC02-05CH11231 (LBL), and DE-FG02-96ER40983 (UTK), the United Kingdom Science and Technology Facilities Council, the Swedish Science Research Council, and by the State of Florida. NR 35 TC 23 Z9 23 U1 0 U2 4 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0370-2693 J9 PHYS LETT B JI Phys. Lett. B PD AUG 11 PY 2011 VL 702 IS 2-3 BP 127 EP 130 DI 10.1016/j.physletb.2011.07.007 PG 4 WC Astronomy & Astrophysics; Physics, Nuclear; Physics, Particles & Fields SC Astronomy & Astrophysics; Physics GA 807US UT WOS:000293928600004 ER PT J AU Morales, R Nenes, A Jonsson, H Flagan, RC Seinfeld, JH AF Morales, R. Nenes, A. Jonsson, H. Flagan, R. C. Seinfeld, J. H. TI Evaluation of an entraining droplet activation parameterization using in situ cloud data SO JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES LA English DT Article ID GLOBAL CLIMATE MODELS; CUMULUS CONVECTION; CRYSTAL-FACE; CCN; SIMULATION; EVOLUTION; SPECTRA; CLOSURE; SCHEME AB This study investigates the ability of a droplet activation parameterization (which considers the effects of entrainment and mixing) to reproduce observed cloud droplet number concentration (CDNC) in ambient clouds. Predictions of the parameterization are compared against cloud averages of CDNC from ambient cumulus and stratocumulus clouds sampled during CRYSTAL-FACE (Key West, Florida, July 2002) and CSTRIPE (Monterey, California, July 2003), respectively. The entrainment parameters required by the parameterization are derived from the observed liquid water content profiles. For the cumulus clouds considered in the study, CDNC is overpredicted by 45% with the adiabatic parameterization. When entrainment is accounted for, the predicted CDNC agrees within 3.5%. Cloud-averaged CDNC for stratocumulus clouds is well captured when entrainment is not considered. In all cases considered, the entraining parameterization compared favorably against a statistical correlation developed from observations to treat entrainment effects on droplet number. These results suggest that including entrainment effects in the calculation of CDNC, as presented here, could address important overprediction biases associated with using adiabatic CDNC to represent cloud-scale average values. C1 [Morales, R.; Nenes, A.] Georgia Inst Technol, Sch Earth & Atmospher Sci, Atlanta, GA 30332 USA. [Flagan, R. C.; Seinfeld, J. H.] CALTECH, Dept Chem Engn, Pasadena, CA 91125 USA. [Jonsson, H.] USN, Ctr Interdisciplinary Remotely Piloted Aircraft S, Postgrad Sch, Monterey, CA 93943 USA. [Nenes, A.] Georgia Inst Technol, Sch Chem & Biomol Engn, Atlanta, GA 30332 USA. [Flagan, R. C.; Seinfeld, J. H.] CALTECH, Dept Environm Sci & Engn, Pasadena, CA 91125 USA. RP Morales, R (reprint author), Georgia Inst Technol, Sch Earth & Atmospher Sci, 311 Ferst Dr, Atlanta, GA 30332 USA. EM ricardo.morales@gatech.edu; athanasios.nenes@gatech.edu; hjonsson@nps.edu; flagan@cheme.caltech.edu; seinfeld@caltech.edu RI Morales Betancourt, Ricardo/A-3827-2016 OI Morales Betancourt, Ricardo/0000-0002-5475-8605 FU NASA-ACMAP; NSF-CAREER; ONR [N00014-10-1-0200] FX We acknowledge support from NASA-ACMAP, NSF-CAREER, and ONR (grant N00014-10-1-0200). We also thank Donifan Barahona, Jeff Snider, and two anonymous reviewers for comments that improved the manuscript. NR 39 TC 8 Z9 8 U1 1 U2 7 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 2169-897X J9 J GEOPHYS RES-ATMOS JI J. Geophys. Res.-Atmos. PD AUG 10 PY 2011 VL 116 AR D15205 DI 10.1029/2010JD015324 PG 9 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA 807NT UT WOS:000293906700003 ER PT J AU Thoppil, PG Richman, JG Hogan, PJ AF Thoppil, Prasad G. Richman, James G. Hogan, Patrick J. TI Energetics of a global ocean circulation model compared to observations SO GEOPHYSICAL RESEARCH LETTERS LA English DT Article ID WESTERN-BOUNDARY-CURRENT; NORTH-ATLANTIC; ABYSSAL CIRCULATION; GENERAL-CIRCULATION; KINETIC-ENERGY; RESOLUTION; TOPEX/POSEIDON; 1/10-DEGREES; SIMULATION; IMPACT AB The majority of the eddy kinetic energy (EKE) in the ocean is found on scales of 50 km to 500 km, encompassed by mesoscale eddies and the meanders and rings of the boundary currents. Mesoscale eddies play a critical role in the dynamics of the ocean circulation with instabilities of the strong mean currents generating eddies in the upper ocean. Interactions between eddies transfer energy from the upper ocean to the deep ocean where eddies interact with bottom topography to generate abyssal mean flows and eddies transfer momentum back to the mean currents. The kinetic energy in a global Hybrid Coordinate Ocean Circulation Model (HYCOM) is compared with long-term observations from surface drifters, geostrophic currents from satellite altimetry, subsurface floats and deep current meter moorings. HYCOM, configured at 1/12.5 degrees (similar to 9 km, typical of the present generation of high resolution models), is deficient in EKE in both the upper and abyssal ocean (depths greater than 3000 m) by similar to 21% and similar to 24% respectively compared to surface drifting buoys and deep current meters. Increasing the model resolution to 1/25 degrees (similar to 4.4 km) or injecting mesoscale eddies through the assimilation of surface observations in a 1/12.5 degrees model increases the surface and the abyssal EKE to levels consistent with the observations. In these models, the surface (abyssal) EKE is increased by 23% (51%) and 15% (46%) for the higher resolution or data-assimilative models, respectively, compared to the 1/12.5 degrees non-assimilative model. While data assimilation increases the EKE in both the upper and abyssal ocean, the kinetic energy of the mean flow in the upper ocean is decreased in the data-assimilative hindcast. C1 [Thoppil, Prasad G.; Richman, James G.; Hogan, Patrick J.] USN, Div Oceanog, Res Lab, Stennis Space Ctr, MS 39529 USA. RP Thoppil, PG (reprint author), USN, Div Oceanog, Res Lab, Stennis Space Ctr, MS 39529 USA. EM prasad.thoppil@nrlssc.navy.mil FU Navy DSRC; Office of Naval Research (ONR) FX This work was supported in part by a grant of computer time from the DOD High Performance Computing Modernization Program at the Navy DSRC. It was sponsored by the Office of Naval Research (ONR) through the NRL projects, Eddy Resolving Global Ocean Prediction Including Tides, Ageostrophic Vorticity Dynamics of the Ocean and Full Column Mixing for Numerical Ocean Models. We thank Robert Scott of the Universite de Bretagne Occidentale for providing the historical current meter data and Joseph Metzger, Ole Martin Smedstad, and Luis Zamudio for making the global HYCOM simulations available. NR 20 TC 23 Z9 24 U1 1 U2 12 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 0094-8276 EI 1944-8007 J9 GEOPHYS RES LETT JI Geophys. Res. Lett. PD AUG 9 PY 2011 VL 38 AR L15607 DI 10.1029/2011GL048347 PG 6 WC Geosciences, Multidisciplinary SC Geology GA 807PB UT WOS:000293911100004 ER PT J AU Cannon, KA Geuther, ME Kelly, CK Lin, S MacArthur, AHR AF Cannon, Kathleen A. Geuther, Meagan E. Kelly, Colin K. Lin, Shirley MacArthur, Amy H. Roy TI Hydrodehalogenation of Aryl Chlorides and Aryl Bromides Using a Microwave-Assisted, Copper-Catalyzed Concurrent Tandem Catalysis Methodology SO ORGANOMETALLICS LA English DT Article ID ONE-POT SYNTHESIS; SONOGASHIRA COUPLING REACTIONS; SOLVENT-FREE CONDITIONS; CONJUGATE ADDITION; LIGAND-FREE; MICHAEL ADDITION; HALIDE EXCHANGE; PALLADIUM; CYCLIZATION; ALKYNES AB A concurrent tandem catalytic methodology has been developed for the hydrodehalogenation of aryl bromides and aryl chlorides. The first step of the tandem catalytic cycle, halogen exchange, produced yields of 84-97% from aryl bromides using 5 mol % CuI catalyst, 10 mol % N,N'-dimethylcyclohexane-1,2-diamine (1), and 2 equiv of NaI in acetonitrile under microwave radiation at 100 degrees C in 0.5-1.5 h. The same reaction for aryl chlorides appeared to be equilibrium-limited after 1 hour at 200 degrees C (yields of 5-44%). Both aryl bromides and aryl chlorides were hydrodehalogenated in 12-87% yield using 20 mol % CuI, 1.5 equiv of diamine 1, and 2 equiv of NaI in acetonitrile at 200 degrees C after 1-2 h. Substrates with oxygen- or nitrogen-containing functional groups had substantially lower yields than hydrocarbon substrates. Deuterium labeling studies suggest that diamine 1 supplies the majority of the hydrogen for the hydrodehalogenation reaction, but solvent can also serve as a source. C1 [Cannon, Kathleen A.; Geuther, Meagan E.; Kelly, Colin K.; Lin, Shirley; MacArthur, Amy H. Roy] USN Acad, Dept Chem, Annapolis, MD 21042 USA. RP Lin, S (reprint author), USN Acad, Dept Chem, 572 Holloway Rd, Annapolis, MD 21042 USA. EM lin@usna.edu FU Office of Naval Research [NN00014110WX30241, N0001409WR40059]; Research Corporation Cottrell College FX K.A.C., M.E.G., and C.K.K. gratefully acknowledge the Office of Naval Research for partial support of this work on funding document NN00014110WX30241. S.L. would like to thank Research Corporation Cottrell College Science Award. A.H.RM. would like to thank the Naval Academy Research Council and the Office of Naval Research for partial support of this work on funding document N0001409WR40059. NR 71 TC 16 Z9 16 U1 4 U2 22 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0276-7333 J9 ORGANOMETALLICS JI Organometallics PD AUG 8 PY 2011 VL 30 IS 15 BP 4067 EP 4073 DI 10.1021/om2003706 PG 7 WC Chemistry, Inorganic & Nuclear; Chemistry, Organic SC Chemistry GA 799SY UT WOS:000293307600020 ER PT J AU Funkhouser, S AF Funkhouser, Scott TI Scattering of Hawking photons as a barrier to particle absorption by black holes SO PHYSICS LETTERS B LA English DT Article DE Black holes; General relativity; Holography; Generalized second law; Particle physics; Hawking radiation AB Electromagnetic scattering interactions between photons emanating from a Schwarzschild black hole and an incident charged particle should generate a repulsive force between the particle and black hole. The net scattering cross-section is calculated here as a function of the mass M of the black hole and the mass m of the particle for scenarios in which the particle is point-like and initially stationary, with proper energy epsilon = m, at some location far from the black hole. It follows from comparing the repulsive scattering force to the corresponding gravitational force that, in order for the particle to be drawn to the black hole, epsilon/T(bh), must be greater than a certain lower bound that is of the order 10(-3) for spin-1/2 or spin-0 particles with unit-charge. Although the scattering, restriction is weaker than the requirement epsilon/T(bh) >> 1 obtained independently from field-theoretic and thermodynamic treatments, the recurrence of a lower bound on the Boltzmann factor epsilon/T(bh) in limitations on particle absorption suggests a physical unity whose nature is fundamentally thermodynamic. Published by Elsevier B.V. C1 USN, Div Sci & Technol, SPAWAR Atlantic Command Ctr, N Charleston, SC 29405 USA. RP Funkhouser, S (reprint author), USN, Div Sci & Technol, SPAWAR Atlantic Command Ctr, N Charleston, SC 29405 USA. EM scott.funkhouser@gmail.com NR 12 TC 0 Z9 0 U1 0 U2 0 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0370-2693 J9 PHYS LETT B JI Phys. Lett. B PD AUG 3 PY 2011 VL 702 IS 1 BP 1 EP 4 DI 10.1016/j.physletb.2011.06.038 PG 4 WC Astronomy & Astrophysics; Physics, Nuclear; Physics, Particles & Fields SC Astronomy & Astrophysics; Physics GA 810QQ UT WOS:000294142600001 ER PT J AU Terraciano, ML Olson, SE Fatemi, FK AF Terraciano, Matthew L. Olson, Spencer E. Fatemi, Fredrik K. TI Temperature-dependent photon scattering in blue-detuned optical traps SO PHYSICAL REVIEW A LA English DT Article ID COLD ATOMS; LASER-BEAMS AB We have observed time-varying spin relaxation of trapped cold atoms due to photon scattering in blue-detuned, crossed, hollow Laguerre-Gaussian beams. These beams are formed by imparting an azimuthal phase of l phi to a Gaussian beam, where l is an integer, and have an intensity distribution that scales with r(2l) to the lowest order. For all degrees of anharmonicity, we observe a time-varying spin-relaxation rate due to energy-dependent photon scattering. For l = 8, we directly measure temperature-dependent scattering rates and show that by removing the most energetic atoms from the trap, a more purely spin-polarized sample remains. The results agree well with Monte Carlo simulations, and we present a simple functional form for the spin-relaxation curves. C1 [Terraciano, Matthew L.; Olson, Spencer E.; Fatemi, Fredrik K.] USN, Res Lab, Washington, DC 20375 USA. RP Terraciano, ML (reprint author), USN, Res Lab, 4555 Overlook Ave SW, Washington, DC 20375 USA. FU Office of Naval Research FX This work was funded by the Office of Naval Research. NR 21 TC 4 Z9 4 U1 1 U2 8 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1050-2947 J9 PHYS REV A JI Phys. Rev. A PD AUG 3 PY 2011 VL 84 IS 2 AR 025402 DI 10.1103/PhysRevA.84.025402 PG 4 WC Optics; Physics, Atomic, Molecular & Chemical SC Optics; Physics GA 801MW UT WOS:000293444700008 ER PT J AU Dollar, F Matsuoka, T Petrov, GM Thomas, AGR Bulanov, SS Chvykov, V Davis, J Kalinchenko, G McGuffey, C Willingale, L Yanovsky, V Maksimchuk, A Krushelnick, K AF Dollar, F. Matsuoka, T. Petrov, G. M. Thomas, A. G. R. Bulanov, S. S. Chvykov, V. Davis, J. Kalinchenko, G. McGuffey, C. Willingale, L. Yanovsky, V. Maksimchuk, A. Krushelnick, K. TI Control of Energy Spread and Dark Current in Proton and Ion Beams Generated in High-Contrast Laser Solid Interactions SO PHYSICAL REVIEW LETTERS LA English DT Article ID PLASMA INTERACTIONS; ACCELERATION; TRANSPORT; ELECTRON; DRIVEN; PULSES; TARGETS; FIELDS; CODE AB By using temporal pulse shaping of high-contrast, short pulse laser interactions with solid density targets at intensities of 2 x 10(21) W cm(-2) at a 45 degrees incident angle, we show that it is possible to reproducibly generate quasimonoenergetic proton and ion energy spectra. The presence of a short pulse prepulse 33 ps prior to the main pulse produced proton spectra with an energy spread between 25% and 60% (Delta E/E) with energy of several MeV, with light ions becoming quasimonoenergetic for 50 nm targets. When the prepulse was removed, the energy spectra was broad. Numerical simulations suggest that expansion of the rear-side contaminant layer allowed for density conditions that prevented the protons from being screened from the sheath field, thus providing a low energy cutoff in the observed spectra normal to the target surface. C1 [Dollar, F.; Matsuoka, T.; Thomas, A. G. R.; Bulanov, S. S.; Chvykov, V.; Kalinchenko, G.; McGuffey, C.; Willingale, L.; Yanovsky, V.; Maksimchuk, A.; Krushelnick, K.] Univ Michigan, Ctr Ultrafast Opt Sci, Ann Arbor, MI 48109 USA. [Petrov, G. M.; Davis, J.] USN, Div Plasma Phys, Res Lab, Washington, DC 20375 USA. RP Dollar, F (reprint author), Univ Michigan, Ctr Ultrafast Opt Sci, Ann Arbor, MI 48109 USA. RI Thomas, Alexander/D-8210-2011; Dollar, Franklin/C-9214-2013; Yanovsky, Victor/B-5899-2008; Kalinchenko, Galina/G-5684-2014; OI Dollar, Franklin/0000-0003-3346-5763; Thomas, Alexander/0000-0003-3206-8512 FU NSF through the Physics Frontier Center FOCUS [PHY-0114336]; Defense Threat Reduction Agency; Naval Research Laboratory FX This work was supported by the NSF through the Physics Frontier Center FOCUS (Grant No. PHY-0114336), as well as by the Defense Threat Reduction Agency and the Naval Research Laboratory. We acknowledge the OSIRIS consortium (UCLA/IST Portugal) for the use of OSIRIS. Simulations were performed on the Nyx Cluster at the University of Michigan. NR 41 TC 19 Z9 22 U1 0 U2 15 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0031-9007 J9 PHYS REV LETT JI Phys. Rev. Lett. PD AUG 3 PY 2011 VL 107 IS 6 AR 065003 DI 10.1103/PhysRevLett.107.065003 PG 5 WC Physics, Multidisciplinary SC Physics GA 801NX UT WOS:000293447900011 PM 21902332 ER PT J AU Nordt, SP Chen, J Clark, RF AF Nordt, Sean Patrick Chen, Jenny Clark, Richard F. TI Severe hypermagnesemia after enteral administration of Epsom salts SO AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY LA English DT Letter C1 [Nordt, Sean Patrick] Los Angeles Cty Univ So Calif Med Ctr, Dept Emergency Med, Sect Toxicol, Los Angeles, CA 90033 USA. [Chen, Jenny] Naval Hosp, Dept Emergency Med, San Diego, CA USA. [Clark, Richard F.] Univ Calif San Diego, Dept Emergency Med, Div Med Toxicol, San Diego, CA 92103 USA. RP Nordt, SP (reprint author), Los Angeles Cty Univ So Calif Med Ctr, Dept Emergency Med, Sect Toxicol, 1200 N State St,Unit 1,Room 1011, Los Angeles, CA 90033 USA. EM spnordt@hotmail.com NR 4 TC 0 Z9 0 U1 1 U2 4 PU AMER SOC HEALTH-SYSTEM PHARMACISTS PI BETHESDA PA 7272 WISCONSIN AVE, BETHESDA, MD 20814 USA SN 1079-2082 J9 AM J HEALTH-SYST PH JI Am. J. Health-Syst. Pharm. PD AUG 1 PY 2011 VL 68 IS 15 BP 1384 EP 1385 DI 10.2146/ajhp100625 PG 2 WC Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA 858CO UT WOS:000297773700007 PM 21785020 ER PT J AU O'Connor, P Buttrey, SE O'Dea, A Kennedy, Q AF O'Connor, Paul Buttrey, Samuel E. O'Dea, Angela Kennedy, Quinn TI Identifying and addressing the limitations of safety climate surveys SO JOURNAL OF SAFETY RESEARCH LA English DT Article DE Safety climate; Safety culture; Survey; Questionnaire; Measurement error ID CULTURE; RECOMMENDATIONS; AVIATION AB Introduction: There are a variety of qualitative and quantitative tools for measuring safety climate. However, questionnaires are by far the most commonly used methodology. Method: This paper reports the descriptive analysis of a large sample of safety climate survey data (n = 110,014) collected over 10 years from U.S. Naval aircrew using the Command Safety Assessment Survey (CSAS). Results: The analysis demonstrated that there was substantial non-random response bias associated with the data (the reverse worded items had a unique pattern of responses, there was a increasing tendency over time to only provide a modal response, the responses to the same item towards the beginning and end of the questionnaire did not correlate as highly as might be expected, and the faster the questionnaire was completed the higher the frequency of modal responses). It is suggested that the non-random responses bias was due to the negative effect on participant motivation of a number of factors (questionnaire design, lack of a belief in the importance of the response, participant fatigue, and questionnaire administration). Conclusions: Researchers must consider the factors that increase the likelihood of non-random measurement error in safety climate survey data and cease to rely on data that are solely collected using a long and complex questionnaire. Impact on Industry: In the absence of valid and reliable data it will not be possible for organizations to take the measures required to improve safety climate. (C) 2011 National Safety Council and Elsevier Ltd. All rights reserved. C1 [O'Connor, Paul] Natl Univ Ireland, Ctr Innovat & Struct Change, Galway, Ireland. [Buttrey, Samuel E.; Kennedy, Quinn] USN, Postgrad Sch, Dept Operat Res, Monterey, CA 93943 USA. RP O'Connor, P (reprint author), Natl Univ Ireland, Ctr Innovat & Struct Change, Galway, Ireland. EM poc73@hotmail.com; buttrey@nps.edu; aodea69@hotmail.com; mqkenned@nps.edu RI OConnor, Paul/H-1221-2011 OI OConnor, Paul/0000-0001-9036-098X NR 32 TC 5 Z9 5 U1 1 U2 15 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0022-4375 J9 J SAFETY RES JI J. Saf. Res. PD AUG PY 2011 VL 42 IS 4 BP 259 EP 265 DI 10.1016/j.jsr.2011.06.005 PG 7 WC Ergonomics; Public, Environmental & Occupational Health; Social Sciences, Interdisciplinary; Transportation SC Engineering; Public, Environmental & Occupational Health; Social Sciences - Other Topics; Transportation GA 850WK UT WOS:000297230100004 PM 22017828 ER PT J AU Hegeler, F McGeoch, MW Sethian, JD Sanders, HD Glidden, SC Myers, MC AF Hegeler, Frank McGeoch, Malcolm W. Sethian, John D. Sanders, Howard D. Glidden, Steven C. Myers, Matthew C. TI A Durable Gigawatt Class Solid State Pulsed Power System SO IEEE TRANSACTIONS ON DIELECTRICS AND ELECTRICAL INSULATION LA English DT Article DE Thyristors; pulse power system; Marx generators; magnetic switches; reliability testing ID ELECTRON-BEAM; FUSION ENERGY; KRF LASERS; GENERATOR; PERFORMANCE; THYRISTOR; EMISSION; SWITCH AB A unique all solid-state pulsed power system has been tested at the Naval Research Laboratory that produced 200 kV, 4.5 kA, and 300 ns pulses, continuously for more than 11,500,000 shots into a resistive load at a repetition rate of 10 pps. The Marx has an efficiency of 80% based on calorimetric measurements. This pulser is used to evaluate components and advance solid state designs for a next generation solid-state pulsed power system to drive an electron beam pumped KrF laser system for inertial fusion energy. The solid state pulser, designed and constructed by PLEX LLC, consists of a 12 stage Marx, coupled with a 3rd harmonic stage to sharpen the Marx output waveforms, a main magnetic switch, a compact pulse forming line used as a transit time isolator, and a resistive load. Each Marx stage uses an APP Model S33A compact high voltage switch that consists of 12 series connected thyristors. A life test on individual thyristors showed operation of > 300 M shots at 20 Hz without failure. C1 [Hegeler, Frank] Commonwealth Technol Inc, Alexandria, VA 22315 USA. [Sethian, John D.; Myers, Matthew C.] USN, Res Lab, Div Plasma Phys, Washington, DC 20375 USA. [McGeoch, Malcolm W.] PLEX LLC, Fall River, MA 02723 USA. [Sanders, Howard D.; Glidden, Steven C.] Appl Pulsed Power Inc, Freeville, NY 13068 USA. RP Hegeler, F (reprint author), Commonwealth Technol Inc, Alexandria, VA 22315 USA. FU DOE; ONR; Naval Research Laboratory FX The work is supported by DOE, ONR, and the Naval Research Laboratory. NR 38 TC 18 Z9 19 U1 0 U2 2 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1070-9878 J9 IEEE T DIELECT EL IN JI IEEE Trns. Dielectr. Electr. Insul. PD AUG PY 2011 VL 18 IS 4 BP 1205 EP 1213 PG 9 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA 807SB UT WOS:000293918900040 ER PT J AU Stemper, BD Storvik, SG Yoganandan, N Baisden, JL Fijalkowski, RJ Pintar, FA Shender, BS Paskoff, GR AF Stemper, Brian D. Storvik, Steven G. Yoganandan, Narayan Baisden, Jamie L. Fijalkowski, Ronald J. Pintar, Frank A. Shender, Barry S. Paskoff, Glenn R. TI A New PMHS Model for Lumbar Spine Injuries During Vertical Acceleration SO JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME LA English DT Article DE biomechanics; bone; compressibility; fracture; injuries ID THORACOLUMBAR BURST FRACTURES; AIR-FORCE; EJECTION EXPERIENCE; CERVICAL-SPINE; LOADING RATE; END-PLATE; MECHANISM; TRAUMA; COMPRESSION; VERTEBRAE AB Ejection from military aircraft exerts substantial loads on the lumbar spine. Fractures remain common, although the overall survivability of the event has considerably increased over recent decades. The present study was performed to develop and validate a biomechanically accurate experimental model for the high vertical acceleration loading to the lumbar spine that occurs during the catapult phase of aircraft ejection. The model consisted of a vertical drop tower with two horizontal platforms attached to a monorail using low friction linear bearings. A total of four human cadaveric spine specimens (T12-L5) were tested. Each lumbar column was attached to the lower platform through a load cell. Weights were added to the upper platform to match the thorax, head-neck, and upper extremity mass of a 50th percentile male. Both platforms were raised to the drop height and released in unison. Deceleration characteristics of the lower platform were modulated by foam at the bottom of the drop tower. The upper platform applied compressive inertial loads to the top of the specimen during deceleration. All specimens demonstrated complex bending during ejection simulations, with the pattern dependent upon the anterior-posterior location of load application. The model demonstrated adequate inter-specimen kinematic repeatability on a spinal level-by-level basis under different subfailure loading scenarios. One specimen was then exposed to additional tests of increasing acceleration to induce identifiable injury and validate the model as an injury-producing system. Multiple noncontiguous vertebral fractures were obtained at an acceleration of 21 g with 488 g/s rate of onset. This clinically relevant trauma consisted of burst fracture at L1 and wedge fracture at L4. Compression of the vertebral body approached 60% during the failure test, with -6,106 N axial force and 168 Nm flexion moment. Future applications of this model include developing a better understanding of the vertebral injury mechanism during pilot ejection and developing tolerance limits for injuries sustained under a variety of different vertical acceleration scenarios. C1 [Stemper, Brian D.; Storvik, Steven G.; Yoganandan, Narayan; Baisden, Jamie L.; Fijalkowski, Ronald J.; Pintar, Frank A.] Med Coll Wisconsin, Dept Neurosurg, Milwaukee, WI 53226 USA. [Stemper, Brian D.; Storvik, Steven G.; Yoganandan, Narayan; Pintar, Frank A.] Marquette Univ, Dept Biomed Engn, Milwaukee, WI 53201 USA. [Stemper, Brian D.; Storvik, Steven G.; Yoganandan, Narayan; Baisden, Jamie L.; Pintar, Frank A.] Vet Affairs Med Ctr, Milwaukee, WI 53295 USA. [Shender, Barry S.; Paskoff, Glenn R.] USN, Air Warfare Ctr, Div Aircraft, Patuxent River, MD 20670 USA. RP Stemper, BD (reprint author), Med Coll Wisconsin, Dept Neurosurg, Milwaukee, WI 53226 USA. EM bstemper@mcw.edu OI Storvik, Steven/0000-0002-6741-3198 FU Office of Naval Research through Naval Air Warfare Center Aircraft Division [N00421-10-C-0049]; Department of Veterans Affairs Medical Research FX This research was supported in part by the Office of Naval Research through Naval Air Warfare Center Aircraft Division Contract N00421-10-C-0049 and the Department of Veterans Affairs Medical Research. NR 56 TC 9 Z9 10 U1 1 U2 15 PU ASME-AMER SOC MECHANICAL ENG PI NEW YORK PA THREE PARK AVE, NEW YORK, NY 10016-5990 USA SN 0148-0731 J9 J BIOMECH ENG-T ASME JI J. Biomech. Eng.-Trans. ASME PD AUG PY 2011 VL 133 IS 8 AR 081002 DI 10.1115/1.4004655 PG 9 WC Biophysics; Engineering, Biomedical SC Biophysics; Engineering GA 825NN UT WOS:000295285600002 PM 21950895 ER PT J AU Ray, MP Feygelson, TI Butler, JE Baldwin, JW Houston, BH Pate, BB Zalalutdinov, MK AF Ray, Matthew P. Feygelson, Tatyana I. Butler, James E. Baldwin, Jeffrey W. Houston, Brian H. Pate, Bradford B. Zalalutdinov, Maxim K. TI Dissipation in single crystal diamond micromechanical annular plate resonators SO DIAMOND AND RELATED MATERIALS LA English DT Article; Proceedings Paper CT 21st European Conference on Diamond, Diamond-Like Materials, Carbon Nanotubes, and Nitrides CY 2010 CL Budapest, HUNGARY DE MEMS; NEMS; Ion Implantation; Sacrificial Layer; Fabrication ID ULTRANANOCRYSTALLINE DIAMOND; ION-IMPLANTATION; FABRICATION; FILMS AB We report measurements of energy dissipation in single crystal diamond annular plate resonators for temperatures ranging from 4 to 300 K. An order of magnitude reduction in dissipation is observed as the temperature is lowered from room temperature (1/Q = 5 x 10(-4)) to 30 K (1/Q = 5 x 10(-5)). (C) 2011 Elsevier B.V. All rights reserved. C1 [Ray, Matthew P.; Butler, James E.; Baldwin, Jeffrey W.; Houston, Brian H.; Pate, Bradford B.; Zalalutdinov, Maxim K.] USN, Res Lab, Washington, DC 20375 USA. [Feygelson, Tatyana I.] SAIC Inc, Washington, DC 20003 USA. RP Pate, BB (reprint author), USN, Res Lab, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM bradford.pate@nrl.navy.mil RI Pate, Bradford/B-4752-2010; OI Pate, Bradford/0000-0002-3288-2947; butler, james/0000-0002-4794-7176 NR 24 TC 6 Z9 6 U1 0 U2 9 PU ELSEVIER SCIENCE SA PI LAUSANNE PA PO BOX 564, 1001 LAUSANNE, SWITZERLAND SN 0925-9635 J9 DIAM RELAT MATER JI Diam. Relat. Mat. PD AUG PY 2011 VL 20 IS 8 BP 1204 EP 1207 DI 10.1016/j.diamond.2011.06.016 PG 4 WC Materials Science, Multidisciplinary SC Materials Science GA 825RW UT WOS:000295300800020 ER PT J AU Hawkins, J Velden, C AF Hawkins, Jeffrey Velden, Christopher TI Supporting Meteorological Field Experiment Missions and Postmission Analysis with Satellite Digital Data and Products SO BULLETIN OF THE AMERICAN METEOROLOGICAL SOCIETY LA English DT Article ID TROPICAL CYCLONE INTENSITY; OBJECTIVE SCHEME; WINDSAT; IMAGERY AB Digital satellite remote-sensing imagery and derived products can greatly aid field project success in terms of both real-time logistics and supporting scientific hypotheses. C1 [Hawkins, Jeffrey] USN, Res Lab, Marine Meteorol Div, Monterey, CA 93923 USA. [Velden, Christopher] Cooperat Inst Meteorol Satellite Studies, Madison, WI USA. RP Hawkins, J (reprint author), USN, Res Lab, Marine Meteorol Div, 7 Grace Hopper Ave,MS 2, Monterey, CA 93923 USA. EM jeffrey.hawkins@nrlmry.navy.mil FU Office of Naval Research's (ONR); PEO [C4ISPACE PMW-120]; NOAA Joint Polar Satellite System (JPSS). FX We would like to acknowledge NOAA for making available the QuikSCAT, AVHRR LAC/GAC, and AMSU digital data from the NOAA LEO satellites, as well as redistributing the EUMETSAT ASCAT and ERS-2 data in near-real time; NASA for providing TRMM data via the TRMM Science Data and Information System (TSDIS) and AMSR-E via the Near Real Time Processing Effort (NRTPE); AFWA/FNMOC for supplying and processing the SSM/I, SSMIS, and OLS data; FNMOC for facilitating access to the Windsat data. CloudSat cloud radar data are available via collaboration with Colorado State University's (CSU) CloudSat Data Processing Center. The MTSAT imagery used during T-PARC/TCS-08 was kindly provided by the Japan Meteorological Agency. Dave Stettner and Derrick Herndon of UW-CIMSS were instrumental in providing data and product flow to the T-PARC/TCS-08 campaign. The NRL TC Web team (Kim Richardson, Tom Lee, Charles Sampson, Mindy Surratt, John Kent, Richard Bankert, Jeremy Solbrig, Steve Miller, and Arunas Kuciauskas) all contributed to the NRL TCS-08 Web products. Pat Harr and Peter Black were instrumental in incorporating the suite of satellite products into daily operations. The authors' T-PARC/TCS-08 satellite support efforts were sponsored by the Office of Naval Research's (ONR) Marine Meteorology Program and leverage other programs sponsored by PEO C4I&SPACE PMW-120 and the NOAA Joint Polar Satellite System (JPSS). NR 20 TC 13 Z9 13 U1 0 U2 2 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 USA SN 0003-0007 J9 B AM METEOROL SOC JI Bull. Amer. Meteorol. Soc. PD AUG PY 2011 VL 92 IS 8 BP 1009 EP 1022 DI 10.1175/2011BAMS3138.1 PG 14 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA 821CE UT WOS:000294951600006 ER PT J AU Burnett, KO Crooker, PP Haegel, NM Yoshioka, Y MacKenzie, D AF Burnett, K. O. Crooker, P. P. Haegel, N. M. Yoshioka, Y. MacKenzie, D. TI Temperature-dependent kinetics of printed polymer light-emitting electrochemical cells SO SYNTHETIC METALS LA English DT Article DE Light-emitting electrochemical cell; Polymer light-emitting diode; Transient response; Thermal activation ID DEVICES; OXIDE AB The thermal activation energy for ion transport and related junction formation in a polymer light-emitting electrochemical cell (LEC) has been determined by measuring the transient behavior of light emission as a function of temperature from 257 K to 297 K. We find the initial time derivative of the light intensity to have an Arrhenius temperature dependence, with an activation energy of 1.6 eV. Our devices utilize a flourene-based polymer emitter which fluoresces at red/near-infrared wavelengths. The polymer matrix includes phenyl alkoxy-substituted PPV and an electrolyte/dopant system based on both solid polymer and ionic liquid dopants. Transient measurements of current and light emission have been used to capture the kinetics of both junction formation and junction decay and to measure variations in optical external quantum efficiency during device turn-on. Published by Elsevier B.V. C1 [Burnett, K. O.; Crooker, P. P.; Haegel, N. M.] USN, Postgrad Sch, Dept Phys, Monterey, CA 93940 USA. [Yoshioka, Y.; MacKenzie, D.] Add Vis Inc, Scotts Valley, CA 95066 USA. RP Crooker, PP (reprint author), USN, Postgrad Sch, Dept Phys, 833 Dyer Rd,Bldg 232, Monterey, CA 93940 USA. EM ppcrooke@nps.edu FU Rapid Reaction Technology Office (RRTO) of the Department of Defense; National Science Foundation [DMR 0804527] FX This work was supported by the Rapid Reaction Technology Office (RRTO) of the Department of Defense and by National Science Foundation Grant DMR 0804527. NR 18 TC 7 Z9 7 U1 3 U2 25 PU ELSEVIER SCIENCE SA PI LAUSANNE PA PO BOX 564, 1001 LAUSANNE, SWITZERLAND SN 0379-6779 J9 SYNTHETIC MET JI Synth. Met. PD AUG PY 2011 VL 161 IS 15-16 BP 1496 EP 1499 DI 10.1016/j.synthmet.2011.04.013 PG 4 WC Materials Science, Multidisciplinary; Physics, Condensed Matter; Polymer Science SC Materials Science; Physics; Polymer Science GA 821JQ UT WOS:000294971700007 ER PT J AU Karovicova, I Wittkowski, M Boboltz, DA Fossat, E Ohnaka, K Scholz, M AF Karovicova, I. Wittkowski, M. Boboltz, D. A. Fossat, E. Ohnaka, K. Scholz, M. TI Mid-infrared interferometric monitoring of evolved stars The dust shell around the Mira variable RR Aquilae at 13 epochs SO ASTRONOMY & ASTROPHYSICS LA English DT Article DE techniques: interferometric; stars: AGB and post-AGB; stars: atmospheres; stars: mass-loss; stars: individual: RR Aql ID ANGULAR SIZE MEASUREMENTS; LONG-PERIOD VARIABLES; RICH AGB STARS; TEMPORAL VARIATIONS; S-ORIONIS; O-CETI; VLBI ASTROMETRY; N-BAND; K-BAND; SPECTRA AB Aims. We present a unique multi-epoch infrared interferometric study of the oxygen-rich Mira variable RR Aql in comparison to radiative transfer models of the dust shell. We investigate flux and visibility spectra at 8-13 mu m with the aim of better understanding the pulsation mechanism and its connection to the dust condensation sequence and mass-loss process. Methods. We obtained 13 epochs of mid-infrared interferometry with the MIDI instrument at the VLTI between April 2004 and July 2007, covering minimum to pre-maximum pulsation phases (0.45-0.85) within four cycles. The data are modeled with a radiative transfer model of the dust shell where the central stellar intensity profile is described by a series of dust-free dynamic model atmospheres based on self-excited pulsation models. We examined two dust species, silicate and Al2O3 grains. We performed model simulations using variations in model phase and dust shell parameters to investigate the expected variability of our mid-infrared photometric and interferometric data. Results. The observed visibility spectra do not show any indication of variations as a function of pulsation phase and cycle. The observed photometry spectra may indicate intracycle and cycle-to-cycle variations at the level of 1-2 standard deviations. The photometric and visibility spectra of RR Aql can be described well by the radiative transfer model of the dust shell that uses a dynamic model atmosphere describing the central source. The best-fitting model for our average pulsation phase of (Phi(V)) over bar = 0.64 +/- 0.15 includes the dynamic model atmosphere M21n (T-model = 2550 K) with a photospheric angular diameter of theta(Phot) = 7.6 +/- 0.6 mas, and a silicate dust shell with an optical depth of tau(V) = 2.8 +/- 0.8, an inner radius of R-in = 4.1 +/- 0.7 R-Phot, and a power-law index of the density distribution of p = 2.6 +/- 0.3. The addition of an Al2O3 dust shell did not improve the model fit. However, our model simulations indicate that the presence of an inner Al2O3 dust shell with lower optical depth than for the silicate dust shell can not be excluded. The photospheric angular diameter corresponds to a radius of R-phot = 520(-140)(+230)R(circle dot) and an effective temperature of T-eff similar to 2420 +/- 200 K. Our modeling simulations confirm that significant intracycle and cycle-to-cycle visibility variations are not expected for RR Aql at mid-infrared wavelengths within our uncertainties. Conclusions. We conclude that our RR Aql data can be described by a pulsating atmosphere surrounded by a silicate dust shell. The effects of the pulsation on the mid-infrared flux and visibility values are expected to be less than about 25% and 20%, respectively, and are too low to be detected within our measurement uncertainties. C1 [Karovicova, I.; Wittkowski, M.] European So Observ, D-85748 Garching, Germany. [Boboltz, D. A.] USN Observ, Washington, DC 20392 USA. [Fossat, E.] LUAN, CNRS UMR 6525, F-06108 Nice 02, France. [Ohnaka, K.] Max Planck Inst Radioastron, D-53121 Bonn, Germany. [Scholz, M.] Heidelberg Univ, Zentrum Astron, Inst Theoret Astrophys, D-69120 Heidelberg, Germany. [Scholz, M.] Univ Sydney, Sch Phys, Sydney Inst Astron, Sydney, NSW 2006, Australia. RP Karovicova, I (reprint author), European So Observ, Karl Schwarzschild Str 2, D-85748 Garching, Germany. EM ikarovic@eso.org; mwittkow@eso.org OI Wittkowski, Markus/0000-0002-7952-9550 NR 63 TC 11 Z9 11 U1 0 U2 2 PU EDP SCIENCES S A PI LES ULIS CEDEX A PA 17, AVE DU HOGGAR, PA COURTABOEUF, BP 112, F-91944 LES ULIS CEDEX A, FRANCE SN 0004-6361 J9 ASTRON ASTROPHYS JI Astron. Astrophys. PD AUG PY 2011 VL 532 AR A134 DI 10.1051/0004-6361/201116527 PG 15 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 807ZS UT WOS:000293942700033 ER PT J AU Schinzel, FK Sokolovsky, KV D'Ammando, F Burnett, TH Max-Moerbeck, W Cheung, CC Fegan, SJ Casandjian, JM Reyes, LC Villata, M Raiteri, CM Agudo, I Calle, OJAB Carosati, D Casas, R Gomez, JL Gurwell, MA Hsiao, HY Jorstad, SG Kimeridze, G Konstantinova, TS Kopatskaya, EN Koptelova, E Kurtanidze, OM Kurtanidze, SO Larionov, VM Larionova, EG Larionova, LV Marscher, AP Morozova, DA Nikolashvili, MG Roca-Sogorb, M Ros, JA Sigua, LA Spiridonova, O Troitsky, IS Vlasyuk, VV Lobanov, AP Zensus, JA AF Schinzel, F. K. Sokolovsky, K. V. D'Ammando, F. Burnett, T. H. Max-Moerbeck, W. Cheung, C. C. Fegan, S. J. Casandjian, J. M. Reyes, L. C. Villata, M. Raiteri, C. M. Agudo, I. Calle, O. J. A. Bravo Carosati, D. Casas, R. Gomez, J. L. Gurwell, M. A. Hsiao, H. Y. Jorstad, S. G. Kimeridze, G. Konstantinova, T. S. Kopatskaya, E. N. Koptelova, E. Kurtanidze, O. M. Kurtanidze, S. O. Larionov, V. M. Larionova, E. G. Larionova, L. V. Marscher, A. P. Morozova, D. A. Nikolashvili, M. G. Roca-Sogorb, M. Ros, J. A. Sigua, L. A. Spiridonova, O. Troitsky, I. S. Vlasyuk, V. V. Lobanov, A. P. Zensus, J. A. TI Identification of gamma-ray emission from 3C 345 and NRAO 512 SO ASTRONOMY & ASTROPHYSICS LA English DT Article DE galaxies: active; quasars: individual: 3C 345; gamma rays: galaxies; quasars: individual: NRAO512; quasars: individual: B3 1640+396 ID ACTIVE GALACTIC NUCLEI; LARGE-AREA TELESCOPE; SWIFT ULTRAVIOLET/OPTICAL TELESCOPE; BL-LACERTAE OBJECTS; ALL-SKY SURVEY; LIKELIHOOD RATIO; SOURCE CATALOG; DATA RELEASE; SOURCE LIST; VARIABILITY AB For more than 15 years, since the days of the Energetic Gamma-Ray Experiment Telescope (EGRET) on board the Compton Gamma-Ray Observatory (CGRO; 1991-2000), it has remained an open question why the prominent blazar 3C 345 was not reliably detected at gamma-ray energies >= 20 MeV. Recently a bright gamma-ray source (0FGL J1641.4+3939/1FGL J1642.5+3947), potentially associated with 3C 345, was detected by the Large Area Telescope (LAT) on Fermi. Multiwavelength observations from radio bands to X-rays (mainly GASP-WEBT and Swift) of possible counterparts (3C 345, NRAO512, B3 1640+396) were combined with 20 months of Fermi-LAT monitoring data (August 2008-April 2010) to associate and identify the dominating gamma-ray emitting counterpart of 1FGL J1642.5+3947. The source 3C 345 is identified as the main contributor for this gamma-ray emitting region. However, after November 2009 (15 months), a significant excess of photons from the nearby quasar NRAO512 started to contribute and thereafter was detected with increasing gamma-ray activity, possibly adding flux to 1FGL J1642.5+3947. For the same time period and during the summer of 2010, an increase of radio, optical and X-ray activity of NRAO512 was observed. No gamma-ray emission from B3 1640+396 was detected. C1 [Schinzel, F. K.; Sokolovsky, K. V.; Lobanov, A. P.; Zensus, J. A.] Max Planck Inst Radioastron, D-53121 Bonn, Germany. [Sokolovsky, K. V.] Astro Space Ctr Lebedev, Inst Phys, Moscow 117997, Russia. [D'Ammando, F.] INAF IASF Palermo, I-90146 Palermo, Italy. [D'Ammando, F.; Larionova, E. G.] INAF IASF Roma, I-00133 Rome, Italy. [Burnett, T. H.] Univ Washington, Dept Phys, Seattle, WA 98195 USA. [Max-Moerbeck, W.] CALTECH, Cahill Ctr Astron & Astrophys, Pasadena, CA 91125 USA. [Cheung, C. C.] Natl Acad Sci, Washington, DC 20001 USA. [Cheung, C. C.] USN, Res Lab, Washington, DC 20375 USA. [Fegan, S. J.] Ecole Polytech, Lab Leprince Ringuet, F-91128 Palaiseau, France. [Casandjian, J. M.] CEA IRFU CNRS Univ Paris Diderot, Lab AIM, Serv Astrophys, CEA Saclay, F-91191 Gif Sur Yvette, France. [Reyes, L. C.] Univ Chicago, Kavli Inst Cosmol Phys, Chicago, IL 60637 USA. [Villata, M.; Raiteri, C. M.] Osserv Astron Torino, INAF, I-10025 Pino Torinese, TO, Italy. [Agudo, I.; Jorstad, S. G.; Marscher, A. P.] Boston Univ, Inst Astrophys Res, Boston, MA 02215 USA. [Agudo, I.; Gomez, J. L.; Roca-Sogorb, M.] CSIC, Inst Astrofis Andalucia, E-18080 Granada, Spain. [Calle, O. J. A. Bravo; Konstantinova, T. S.; Kopatskaya, E. N.; Larionov, V. M.; Larionova, L. V.; Morozova, D. A.; Troitsky, I. S.] St Petersburg State Univ, Astron Inst, St Petersburg, Russia. [Carosati, D.] EPT Observ, Tijarafe, La Palma, Spain. [Carosati, D.] TNG Fdn Galileo Galilei, INAF, La Palma, Spain. [Casas, R.] Inst Ciencies Espai IEEC CSIC, Barcelona 08193, Spain. [Gurwell, M. A.] Harvard Smithsonian Ctr Astrophys, Cambridge, MA 02138 USA. [Hsiao, H. Y.; Koptelova, E.] Natl Cent Univ, Grad Inst Astron, Jhongli 32054, Taiwan. [Kimeridze, G.; Kurtanidze, O. M.; Kurtanidze, S. O.; Nikolashvili, M. G.; Sigua, L. A.] Abastumani Observ, GE-0301 Mt Kanobili, Abastumani, Rep of Georgia. [Larionov, V. M.] Isaac Newton Inst Chile, St Petersburg Branch, St Petersburg, Russia. [Larionov, V. M.] Pulkovo Astron Observ, St Petersburg 196140, Russia. [Ros, J. A.] Agrupacio Astron Sabadell, Sabadell 08206, Spain. [Spiridonova, O.; Vlasyuk, V. V.] Special Astrophys Observ, Nizhnii Arkhyz 369167, Karachai Cherke, Russia. RP Schinzel, FK (reprint author), Max Planck Inst Radioastron, Hugel 69, D-53121 Bonn, Germany. EM schinzel@mpifr-bonn.mpg.de RI Larionov, Valeri/H-1349-2013; Kopatskaya, Evgenia/H-4720-2013; Larionova, Elena/H-7287-2013; Lobanov, Andrei/G-5891-2014; Kurtanidze, Omar/J-6237-2014; Sokolovsky, Kirill/D-2246-2015; Agudo, Ivan/G-1701-2015; Morozova, Daria/H-1298-2013; Troitskiy, Ivan/K-7979-2013; Jorstad, Svetlana/H-6913-2013; Grishina, Tatiana/H-6873-2013; OI Villata, Massimo/0000-0003-1743-6946; Larionov, Valeri/0000-0002-4640-4356; Kopatskaya, Evgenia/0000-0001-9518-337X; Larionova, Elena/0000-0002-2471-6500; Sokolovsky, Kirill/0000-0001-5991-6863; Agudo, Ivan/0000-0002-3777-6182; Morozova, Daria/0000-0002-9407-7804; Troitskiy, Ivan/0000-0002-4218-0148; Jorstad, Svetlana/0000-0001-9522-5453; Grishina, Tatiana/0000-0002-3953-6676; Larionova, Liudmila/0000-0002-0274-1481 FU International Max Planck Research School (IMPRS) for Astronomy and Astrophysics at the Universities of Bonn and Cologne; Russian RFBR foundation [09-02-00092]; Spanish Ministry of Science and Innovation; Regional Government of Andalucia [AYA2007-67626-C03-03, P09-FQM-4784]; Georgian National Science Foundation [GNSF/ST08/4-404]; NASA [NNX08AV65G, NNX08AV61G, NNX09AT99G]; National Science Foundation [AST-0907893]; Smithsonian Institution; Academia Sinica FX The authors would like to thank Ann Wehrle, Benoit Lott, Seth Digel, Gino Tosti, Dave Thompson, and Greg Taylor for their helpful comments and useful discussions, which improved the quality of this manuscript. We thank the A&A referee for extensive comments. The Fermi-LAT Collaboration acknowledges generous ongoing support from a number of agencies and institutes that have supported both the development and the operation of the LAT as well as scientific data analysis. These include the National Aeronautics and Space Administration and the Department of Energy in the United States, the Commissariat a l'Energie Atomique and the Centre National de la Recherche Scientifique/Institut National de Physique Nucleaire et de Physique des Particules in France, the Agenzia Spaziale Italiana and the Istituto Nazionale di Fisica Nucleare in Italy, the Ministry of Education, Culture, Sports, Science and Technology (MEXT), High Energy Accelerator Research Organization (KEK) and Japan Aerospace Exploration Agency (JAXA) in Japan, and the K. A. Wallenberg Foundation, the Swedish Research Council and the Swedish National Space Board in Sweden. Additional support for science analysis during the operations phase is gratefully acknowledged from the Istituto Nazionale di Astrofisica in Italy and the Centre National d'Etudes Spatiales in France. Frank Schinzel and Kirill Sokolovsky were supported for this research through a stipend from the International Max Planck Research School (IMPRS) for Astronomy and Astrophysics at the Universities of Bonn and Cologne. M. Villata organized the optical-to-radio observations by GASP-WEBT as the president of the collaboration. Additional support for science analysis during the operations phase is gratefully acknowledged from the Istituto Nazionale di Astrofisica in Italy and the Centre National d'Etudes Spatiales in France. The St. Petersburg University team acknowledges support from Russian RFBR foundation via grant 09-02-00092. Acquisition of the MAPCAT data is supported in part by the Spanish Ministry of Science and Innovation and the Regional Government of Andalucia through grants AYA2007-67626-C03-03 and P09-FQM-4784, respectively. The Abastumani team acknowledges financial support by the Georgian National Science Foundation through grant GNSF/ST08/4-404. A. Marscher and S. Jorstad received support for this work from NASA grants NNX08AV65G, NNX08AV61G, and NNX09AT99G, and National Science Foundation grant AST-0907893 to Boston University. The Submillimeter Array is a joint project between the Smithsonian Astrophysical Observatory and the Academia Sinica Institute of Astronomy and Astrophysics and is funded by the Smithsonian Institution and the Academia Sinica. This paper is partly based on observations carried out at the German-Spanish Calar Alto Observatory, which is jointly operated by the MPIA and the IAA-CSIC. This research has made use of NASA's Astrophysics Data System, the SIMBAD database, operated at CDS, Strasbourg, France and the NASA/IPAC Extragalactic Database (NED) which is operated by the JPL, Caltech, under contract with NASA. This research has made use of data from the MOJAVE database that is maintained by the MOJAVE team (Lister et al. 2009). NR 59 TC 2 Z9 2 U1 0 U2 4 PU EDP SCIENCES S A PI LES ULIS CEDEX A PA 17, AVE DU HOGGAR, PA COURTABOEUF, BP 112, F-91944 LES ULIS CEDEX A, FRANCE SN 0004-6361 J9 ASTRON ASTROPHYS JI Astron. Astrophys. PD AUG PY 2011 VL 532 AR A150 DI 10.1051/0004-6361/201016145 PG 11 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 807ZS UT WOS:000293942700049 ER PT J AU Smith, KA AF Smith, Katherine A. TI CAN FINANCING CONSTRAINTS EXPLAIN THE ASSET PRICING PUZZLES IN PRODUCTION ECONOMIES? SO INTERNATIONAL ECONOMIC REVIEW LA English DT Article ID BUSINESS CYCLES; RETURNS; INVESTMENT; FLUCTUATIONS; PRICES; COSTS AB General Equilibrium asset pricing models have a difficult time simultaneously delivering a sizable equity premium, a low and counter cyclical real risk free rate, and cyclical variation in return volatility. To explain these stylized facts, this article introduces occasionally binding financing constraints that impede producers' ability to invest. The financial frictions drive a wedge between the marginal rate of substitution and firms' internal stochastic discount factors so that the shadow value of capital is not tied to the average price of capital. The model delivers higher and more volatile asset returns during recessions as well as a counter cyclical equity premium. C1 USN Acad, Dept Econ, Annapolis, MD 21402 USA. RP Smith, KA (reprint author), USN Acad, Dept Econ, 589 McNair Rd, Annapolis, MD 21402 USA. EM ksmith@usna.edu NR 31 TC 0 Z9 0 U1 1 U2 5 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0020-6598 J9 INT ECON REV JI Int. Econ. Rev. PD AUG PY 2011 VL 52 IS 3 BP 739 EP 765 DI 10.1111/j.1468-2354.2011.00648.x PG 27 WC Economics SC Business & Economics GA 815ZM UT WOS:000294568500008 ER PT J AU Jensen, KL Montgomery, EJ Feldman, DW O'Shea, PG Harris, JR Lewellen, JW Moody, N AF Jensen, Kevin L. Montgomery, Eric J. Feldman, Donald W. O'Shea, Patrick G. Harris, John R. Lewellen, John W. Moody, Nathan TI Multiple scattering effects on quantum efficiency and response time for cesiated metal photocathodes SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID ELECTRONIC WORK FUNCTION; HIGH-AVERAGE-POWER; PHOTOELECTRIC-EMISSION; BAND-STRUCTURE; PHOTOEMISSION; ENERGY; TUNGSTEN; SURFACE; CESIUM; MODEL AB An oft used approximation to predict quantum efficiency (QE) from bare metals or those with a low work function coating such as cesium is to assume that photo-excited electrons have not scattered prior to their emission. Monte Carlo simulations are used to assess that approximation, and show that, while good for bare metals, for cesiated metals a photoexcited electron may undergo several scattering events and yet be emitted. Neglecting scattered electrons therefore underestimates QE. Emitted electrons that have undergone scattering before emission elongate the response time by giving rise to a long time tail, low energy contribution to the faster non-scattered emission, for which a model is developed. The theory is applied to study variations in QE as a function of wavelength measured from cesiated metal surfaces. The extension of the findings to semiconductor photocathodes is briefly discussed. (C) 2011 American Institute of Physics. [doi:10.1063/1.3610397] C1 [Jensen, Kevin L.] USN, ESTD, Res Lab, Washington, DC 20375 USA. [Montgomery, Eric J.; Feldman, Donald W.; O'Shea, Patrick G.] Univ Maryland, IREAP, College Pk, MD 20742 USA. [Harris, John R.; Lewellen, John W.] USN, Dept Phys, Postgrad Sch, Monterey, CA 93943 USA. [Moody, Nathan] Los Alamos Natl Lab, Los Alamos, NM 87545 USA. RP Jensen, KL (reprint author), USN, ESTD, Res Lab, Code 6840, Washington, DC 20375 USA. EM kevin.jensen@nrl.navy.mil RI Jensen, Kevin/I-1269-2015 OI Jensen, Kevin/0000-0001-8644-1680 FU Joint Technology Office (JTO); Office of Naval Research (ONR) FX We thank the Joint Technology Office (JTO) and the Office of Naval Research (ONR) for their support of this work. We thank D. Dowell for access to the experimental data shown in Fig. 18, and both him and J. Smedley (Brookhaven National Laboratory) for discussions. NR 75 TC 4 Z9 4 U1 0 U2 8 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0021-8979 J9 J APPL PHYS JI J. Appl. Phys. PD AUG 1 PY 2011 VL 110 IS 3 AR 034504 DI 10.1063/1.3610397 PG 13 WC Physics, Applied SC Physics GA 808DN UT WOS:000293956600143 ER PT J AU Siskind, DE Stevens, MH Hervig, M Sassi, F Hoppel, K Englert, CR Kochenash, AJ AF Siskind, David E. Stevens, Michael H. Hervig, Mark Sassi, Fabrizio Hoppel, Karl Englert, Christoph R. Kochenash, Andrew J. TI Consequences of recent Southern Hemisphere winter variability on polar mesospheric clouds SO JOURNAL OF ATMOSPHERIC AND SOLAR-TERRESTRIAL PHYSICS LA English DT Article DE Polar mesospheric clouds; Mesopause; Teleconnections ID NORTHERN SUMMER PROGRAM; MIDDLE ATMOSPHERE; WAVE ACTIVITY; MODEL; TEMPERATURES; CIRCULATION; DYNAMICS AB Variations in the Southern Hemisphere (SH) winter of 2007, 2008 and 2009 had important consequences on polar mesospheric clouds (PMCs) observed in the corresponding Northern summers. Specifically, the stratospheric SH winter of 2007 was observed to be warmer than in 2008 and 2009. Using the high altitude analysis from the Navy Operational Global Atmospheric Prediction System-Advanced Level Physics High Altitude (NOGAPS-ALPHA) forecast/assimilation system we show that this warmth was linked to similar temperature increases in the high latitude summer mesosphere. These temperature changes led to a dramatic reduction in PMC occurrence (factor of 5-6) recorded by the SHIMMER instrument at sub-arctic latitudes and a factor of 2 decrease in total ice water content in PMCs seen by the SOFIE instrument on the NASA AIM satellite. Microphysical modeling confirms the overall effect of these temperature changes on PMCs at high latitudes; however, a detailed comparison of the cloud occurrence with the SHIMMER data for all three years shows that the clouds are associated with a surprisingly wide range (130-165 K) of temperatures. Published by Elsevier Ltd. C1 [Siskind, David E.; Stevens, Michael H.; Sassi, Fabrizio; Englert, Christoph R.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. [Hervig, Mark] GATS Inc, Driggs, ID USA. [Hoppel, Karl] USN, Res Lab, Remote Sensing Div, Washington, DC 20375 USA. [Kochenash, Andrew J.] Computat Phys Inc, Springfield, VA USA. RP Siskind, DE (reprint author), USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. EM siskind@nrl.navy.mil OI Englert, Christoph/0000-0002-2145-6168; Stevens, Michael/0000-0003-1082-8955; Sassi, Fabrizio/0000-0002-9492-7434 FU Office of Naval Research; NASA AIM; DoD Supercomputing Resource Centers FX This work was supported by grants from the Office of Naval Research and the NASA AIM Science project. SHIMMER was a joint project between NRL, the DoD Space Test Program and the NASA Heliophysics Division. The NOGAPS-ALPHA analysis is also supported by a grant of computer time from the DoD Supercomputing Resource Centers. We thank Larry Coy for providing estimates of the vertical wind used in the CARMA calculations. Finally, we thank the entire AIM team led by J. M. Russell III for producing an excellent dataset. NR 38 TC 17 Z9 17 U1 0 U2 6 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 1364-6826 J9 J ATMOS SOL-TERR PHY JI J. Atmos. Sol.-Terr. Phys. PD AUG PY 2011 VL 73 IS 13 BP 2013 EP 2021 DI 10.1016/j.jastp.2011.06.014 PG 9 WC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences SC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences GA 816IL UT WOS:000294591800045 ER PT J AU Matteucci, MJ Griffith, EA Tantama, SS Tanen, DA AF Matteucci, Michael J. Griffith, Erin A. Tantama, Stephen S. Tanen, David A. TI Response to Effect of Deferasirox on Iron Absorption in a Randomized, Placebo-Controlled, Crossover Study in a Human Model of Acute Supratherapeutic Iron Ingestion Reply SO ANNALS OF EMERGENCY MEDICINE LA English DT Letter C1 [Matteucci, Michael J.; Griffith, Erin A.; Tantama, Stephen S.; Tanen, David A.] USN, Med Ctr, Dept Emergency Med, San Diego, CA 92152 USA. RP Matteucci, MJ (reprint author), USN, Med Ctr, Dept Emergency Med, San Diego, CA 92152 USA. NR 4 TC 0 Z9 0 U1 0 U2 4 PU MOSBY-ELSEVIER PI NEW YORK PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA SN 0196-0644 J9 ANN EMERG MED JI Ann. Emerg. Med. PD AUG PY 2011 VL 58 IS 2 BP 220 EP 220 DI 10.1016/j.annemergmed.2011.03.055 PG 1 WC Emergency Medicine SC Emergency Medicine GA 806JN UT WOS:000293803800025 ER PT J AU Deen, DA Champlain, JG AF Deen, David A. Champlain, James G. TI High frequency capacitance-voltage technique for the extraction of interface trap density of the heterojunction capacitor: Terman's method revised SO APPLIED PHYSICS LETTERS LA English DT Article AB In a multi-layer heterojunction system, the interface responsible for trap charging is spatially displaced from the two-dimensional charge gas, in contrast to the typical SiO(2)/Si capacitor. This displacement causes the effective trap capacitance to occur in a different configuration than that of the SiO(2)/Si system that Terman originally considered. The adaptation of Terman's high frequency capacitance-voltage method for interface trap density extraction is developed for the heterojunction multi-layer capacitor. [doi: 10.1063/1.3615279] C1 [Deen, David A.; Champlain, James G.] USN, Res Lab, Elect Sci & Technol Div, Washington, DC 20375 USA. RP Deen, DA (reprint author), USN, Res Lab, Elect Sci & Technol Div, Washington, DC 20375 USA. EM deen@svta.com; james.champlain@nrl.navy.mil FU Office of Naval Research FX This work was supported by the Office of Naval Research. NR 5 TC 10 Z9 10 U1 0 U2 12 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD AUG 1 PY 2011 VL 99 IS 5 AR 053501 DI 10.1063/1.3615279 PG 3 WC Physics, Applied SC Physics GA 803XV UT WOS:000293617300097 ER PT J AU Lou, JW Villarruel, CA Schermer, RT AF Lou, Janet W. Villarruel, Carl A. Schermer, Ross T. TI Optically activated core flow shifting within a focused flow SO APPLIED PHYSICS LETTERS LA English DT Article AB We report on the application of an optical beam to redirect sheathed micro-fluidic flow without direct interaction with the sample. The hydrodynamic properties of the sheath are locally modified due to optical heating, resulting in a spatial shift of the sample flow. We characterize this technique for a range of flow rates and demonstrate up to 100 mu m shift at peak flow velocities of 19 mm/s. We also model the temperature and viscosity changes, as well as the flow velocity profiles for a two-fluid flow with different viscosities. The calculated shifts in the flow profile correspond well with the measured shifts. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3623443] C1 [Lou, Janet W.] Sotera Def Solut Inc, Miss Syst Div, Crofton, MD 21114 USA. [Villarruel, Carl A.; Schermer, Ross T.] USN, Res Lab, Div Opt Sci, Washington, DC 20375 USA. RP Lou, JW (reprint author), Sotera Def Solut Inc, Miss Syst Div, Crofton, MD 21114 USA. EM janet.lou@soteradefense.com FU Office of Naval Research [6336-C1] FX This work is supported by the Office of Naval Research (WU#6336-C1). The authors would like to thank Peter B. Howell, Jr. of the U.S. Naval Research Laboratory for providing the micro-fluidic flow channel. NR 8 TC 2 Z9 2 U1 0 U2 3 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD AUG 1 PY 2011 VL 99 IS 5 AR 054102 DI 10.1063/1.3623443 PG 3 WC Physics, Applied SC Physics GA 803XV UT WOS:000293617300105 ER PT J AU Elsberry, RL Jordan, MS Vitart, F AF Elsberry, Russell L. Jordan, Mary S. Vitart, Frederic TI Evaluation of the ECMWF 32-day ensemble predictions during 2009 season of western North Pacific tropical cyclone events on intraseasonal timescales SO ASIA-PACIFIC JOURNAL OF ATMOSPHERIC SCIENCES LA English DT Article DE Tropical cyclone formation prediction; intraseasonal predictability of tropical cyclone events; ECMWF 32-day ensemble prediction model ID TRACK FORECAST ERRORS AB The performance of the ECMWF 32-day ensemble predictions of western North Pacific tropical cyclone events (formation plus track) made once a week during the 2009 season is evaluated with the same procedures as for the 2008 season. Seventeen of the 23 tropical cyclones during the 2009 season occurred during multiple storm scenarios that are more difficult to predict, and many of the deficient track predictions involved unusual and rapidly changing tracks that typically involve interactions with adjacent synoptic circulations that are not predictable on intraseasonal timescales (10-30 days). Such incorrect predictions of the duration and tracks of these multiple cyclones were found to degrade the performance in predicting subsequent tropical cyclone formations and tracks during the 32-day integration. Predominantly northward tracks throughout the life cycle tended to be less predictable on intraseasonal timescales. Given these caveats, the overall performance of the ECMWF ensemble for the 12 typhoons was more successful than during the 2008 season. However, the performance for three tropical storms during the 2009 season was less successful due to the difficult track forecast scenarios. A surprisingly good performance was found in predicting the formation location and early track segments of eight minimal tropical storms or tropical depressions. The less satisfactory aspect for many of the late season tropical depressions was that the ECMWF ensemble continued to predict member vortices for extended periods after the system had actually dissipated. C1 [Elsberry, Russell L.; Jordan, Mary S.] Naval Postgrad Sch, Dept Meteorol, Monterey, CA USA. RP Elsberry, RL (reprint author), Naval Postgrad Sch, Dept Meteorol, 589 Dyer Rd,Room 254, Monterey, CA USA. EM Elsberry@nps.edu FU Office of Naval Research Marine Meteorology Division and Oceanography Division FX The Office of Naval Research Marine Meteorology Division and Oceanography Division have provided the support for R. L. Elsberry and M. S. Jordan. The ECMWF kindly provided the 32-day ensemble vortex tracks each week. Mrs. Penny Jones expertly prepared the manuscript. NR 7 TC 8 Z9 8 U1 0 U2 1 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1976-7633 J9 ASIA-PAC J ATMOS SCI JI Asia-Pac. J. Atmos. Sci. PD AUG PY 2011 VL 47 IS 4 BP 305 EP 318 DI 10.1007/s13143-011-0017-8 PG 14 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA 812MB UT WOS:000294296500001 ER PT J AU Springborg, R AF Springborg, Robert TI Economic Involvements of Militaries SO INTERNATIONAL JOURNAL OF MIDDLE EAST STUDIES LA English DT Editorial Material C1 USN, Dept Natl Secur Affairs, Postgrad Sch, Monterey, CA USA. RP Springborg, R (reprint author), USN, Dept Natl Secur Affairs, Postgrad Sch, Monterey, CA USA. EM rdspring@nps.edu NR 0 TC 4 Z9 4 U1 1 U2 2 PU CAMBRIDGE UNIV PRESS PI NEW YORK PA 32 AVENUE OF THE AMERICAS, NEW YORK, NY 10013-2473 USA SN 0020-7438 J9 INT J MIDDLE E STUD JI Int. J. Middle East Stud. PD AUG PY 2011 VL 43 IS 3 BP 397 EP 399 DI 10.1017/S0020743811000559 PG 3 WC Area Studies SC Area Studies GA 802YC UT WOS:000293545900015 ER PT J AU Dropkin, AM Huyer, SA Henoch, C AF Dropkin, Amanda M. Huyer, Stephen A. Henoch, Charles TI Combined Experimental/Numerical Development of Propulsor Evaluation Capability SO JOURNAL OF FLUIDS ENGINEERING-TRANSACTIONS OF THE ASME LA English DT Article ID PROPELLERS; PUMP AB This paper presents a method to combine computational fluid dynamics (CFD) modeling with subscale experiments to improve full-scale propulsor performance prediction. Laboratory experiments were conducted on subscale models of the NUWC Light underwater vehicle in the 0.3048 m x 0.3048 m water tunnel located at the Naval Undersea Warfare Center in Newport, Rhode Island. This model included an operational rim-driven ducted post-swirl propulsor. Laser Doppler Velocimetry was used to measure several velocity profiles along the hull. The experimental data were used in this project to validate the CFD models constructed using the commercial CFD software package, Fluent VR. Initially, axisymmetric two-dimensional simulations investigated the bare hull, hull only case, and a shrouded body without the propulsor. These models were selected to understand the axisymmetric flow development and investigate methods to best match the propulsor inflow. A variety of turbulence models were investigated and ultimately the numerical and experimental velocity profiles were found to match within 3%. Full 3D flow simulations were then conducted with an operating propulsor and compared with the corresponding subscale experimental data. Finally, simulations were conducted for full-scale tests and compared with actual open-water data. While the open-water data was limited to propulsor rpm and vehicle velocity, the operating advance ratio could be determined as well as the estimated vehicle thrust. This provided a method to utilize CFD/experiments to bridge the gap between subscale and full-scale tests. The predicted open-water advance ratio was 10.3% higher than the experimental value, as compared with the 28% difference previously found from a linear extrapolation of Reynolds number from model scale to full scale. This method was then applied to two different research propulsor geometries and led to agreement between computational and experimental advance ratios on the order of 2%. [DOI: 10.1115/1.4004387] C1 [Dropkin, Amanda M.; Huyer, Stephen A.; Henoch, Charles] USN, Undersea Warfare Ctr, Newport, RI 02841 USA. RP Dropkin, AM (reprint author), USN, Undersea Warfare Ctr, Code 8233,Bldg 1302-2, Newport, RI 02841 USA. EM Amanda.Dropkin@navy.mil FU Naval Undersea Warfare Center Division Newport; Office of Naval Research [N0001410WX20326] FX This research was sponsored by the Naval Undersea Warfare Center Division Newport under the New Professional Research Program and the Office of Naval Research under Contract N0001410WX20326, Dr. Scott Hassan program manager. NR 15 TC 3 Z9 3 U1 1 U2 9 PU ASME PI NEW YORK PA THREE PARK AVE, NEW YORK, NY 10016-5990 USA SN 0098-2202 J9 J FLUID ENG-T ASME JI J. Fluids Eng.-Trans. ASME PD AUG PY 2011 VL 133 IS 8 AR 081105 DI 10.1115/1.4004387 PG 9 WC Engineering, Mechanical SC Engineering GA 814WQ UT WOS:000294488300005 ER PT J AU Fredriksson, DW Faessel, S Doherty, C Hampton, M Harvey, E Rudewicz, J AF Fredriksson, David W. Faessel, Sara Doherty, Colin Hampton, Michael Harvey, Ethan Rudewicz, Jenny TI A SUBMERSIBLE OYSTER AQUACULTURE SYSTEM FOR THE CHESAPEAKE BAY SO JOURNAL OF SHELLFISH RESEARCH LA English DT Meeting Abstract C1 [Fredriksson, David W.; Faessel, Sara; Doherty, Colin; Hampton, Michael; Harvey, Ethan; Rudewicz, Jenny] USN Acad, Annapolis, MD 21402 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU NATL SHELLFISHERIES ASSOC PI GROTON PA C/O DR. SANDRA E. SHUMWAY, UNIV CONNECTICUT, 1080 SHENNECOSSETT RD, GROTON, CT 06340 USA SN 0730-8000 J9 J SHELLFISH RES JI J. Shellfish Res. PD AUG PY 2011 VL 30 IS 2 BP 507 EP 507 PG 1 WC Fisheries; Marine & Freshwater Biology SC Fisheries; Marine & Freshwater Biology GA 812SC UT WOS:000294312200122 ER PT J AU Rahall, B Steppe, C Westby, SR Tagan, P AF Rahall, Bethany Steppe, Cecily Westby, Stephanie Reynolds Tagan, Patrick TI A COMPARISON OF GROWTH AND OVER-WINTER MORTALITY OF HATCHERY-REARED CRASSOSTREA VIRGINICA SPAT SET IN TANKS AND IN A FIELD ENCLOSURE SO JOURNAL OF SHELLFISH RESEARCH LA English DT Meeting Abstract C1 [Rahall, Bethany; Steppe, Cecily; Tagan, Patrick] USN Acad, Annapolis, MD 21402 USA. [Westby, Stephanie Reynolds] NOAA, Restorat Ctr, Annapolis, MD 21403 USA. RI Steppe, Cecily/K-3388-2012 OI Steppe, Cecily/0000-0002-5448-3533 NR 0 TC 1 Z9 1 U1 0 U2 2 PU NATL SHELLFISHERIES ASSOC PI GROTON PA C/O DR. SANDRA E. SHUMWAY, UNIV CONNECTICUT, 1080 SHENNECOSSETT RD, GROTON, CT 06340 USA SN 0730-8000 J9 J SHELLFISH RES JI J. Shellfish Res. PD AUG PY 2011 VL 30 IS 2 BP 546 EP 546 PG 1 WC Fisheries; Marine & Freshwater Biology SC Fisheries; Marine & Freshwater Biology GA 812SC UT WOS:000294312200253 ER PT J AU Rittschof, D Dickinson, G Wahl, K Vega, I Everett, R Orihuela, B AF Rittschof, Dan Dickinson, Gary Wahl, Kathryn Vega, Irving Everett, Richard Orihuela, Beatriz TI BIOLOGICAL GLUES AS ORGANIZERS OF MARINE COMMUNITIES SO JOURNAL OF SHELLFISH RESEARCH LA English DT Meeting Abstract C1 [Rittschof, Dan; Orihuela, Beatriz] Duke Univ, Beaufort, NC 28516 USA. [Dickinson, Gary] Univ Pittsburgh, Sch Dent Med, Pittsburgh, PA 15261 USA. [Wahl, Kathryn; Everett, Richard] USN, Res Lab, Washington, DC 20375 USA. [Vega, Irving] Univ Puerto Rico, San Juan, PR 00931 USA. NR 0 TC 0 Z9 0 U1 0 U2 1 PU NATL SHELLFISHERIES ASSOC PI GROTON PA C/O DR. SANDRA E. SHUMWAY, UNIV CONNECTICUT, 1080 SHENNECOSSETT RD, GROTON, CT 06340 USA SN 0730-8000 J9 J SHELLFISH RES JI J. Shellfish Res. PD AUG PY 2011 VL 30 IS 2 BP 548 EP 548 PG 1 WC Fisheries; Marine & Freshwater Biology SC Fisheries; Marine & Freshwater Biology GA 812SC UT WOS:000294312200261 ER PT J AU Cunningham, PD Boercker, JE Foos, EE Lumb, MP Smith, AR Tischler, JG Melinger, JS AF Cunningham, Paul D. Boercker, Janice E. Foos, Edward E. Lumb, Matthew P. Smith, Anthony R. Tischler, Joseph G. Melinger, Joseph S. TI Enhanced Multiple Exciton Generation in Quasi-One-Dimensional Semiconductors SO NANO LETTERS LA English DT Article DE Multiple exciton generation; carrier multiplication; nanorods; nanocrystals; photovoltaic ID PBSE QUANTUM DOTS; EFFICIENCY CARRIER MULTIPLICATION; SOLAR-CELLS; CONVERSION EFFICIENCY; COLLOIDAL PBSE; NANOCRYSTALS; PHOTOLUMINESCENCE; ABSORPTION; ARRAYS; LIMITS AB The creation of a single electron-hole pair (i.e., exciton) per incident photon is a fundamental limitation for current optoelectronic devices including photodetectors and photovoltaic cells. The prospect of multiple exciton generation per incident photon is of great interest to fundamental science and the improvement of solar cell technology. Multiple exciton generation is known to occur in semiconductor nanostructures with increased efficiency and reduced threshold energy compared to their bulk counterparts. Here we report a significant enhancement of multiple exciton generation in PbSe quasi-one-dimensional semiconductors (nanorods) over zero-dimensional nanostructures (nanocrystals), characterized by a 2-fold increase in efficiency and reduction of the threshold energy to (2.23 +/- 0.03)E(g), which approaches the theoretical limit of 2E(g). Photovoltaic cells based on PbSe nanorods are capable of improved power conversion efficiencies, in particular when operated in conjunction with solar concentrators. C1 [Cunningham, Paul D.; Boercker, Janice E.; Foos, Edward E.; Lumb, Matthew P.; Smith, Anthony R.; Tischler, Joseph G.; Melinger, Joseph S.] USN, Res Lab, Washington, DC 20375 USA. [Lumb, Matthew P.] George Washington Univ, Sch Engn & Appl Sci, Washington, DC 20052 USA. RP Cunningham, PD (reprint author), USN, Res Lab, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM paul.cunningham.ctr@nrl.navy.mil FU U.S. Naval Research Laboratory FX This research was performed while P. D. Cunningham and A. R Smith held National Research Council Research Associateship Awards at the U.S. Naval Research Laboratory. We thank Sasha Efros for helpful discussions of MEG and Auger recombination. NR 47 TC 73 Z9 74 U1 2 U2 46 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1530-6984 J9 NANO LETT JI Nano Lett. PD AUG PY 2011 VL 11 IS 8 BP 3476 EP 3481 DI 10.1021/nl202014a PG 6 WC Chemistry, Multidisciplinary; Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter SC Chemistry; Science & Technology - Other Topics; Materials Science; Physics GA 804PJ UT WOS:000293665600071 PM 21766838 ER PT J AU Barry, JD Wills, BK AF Barry, J. Dave Wills, Brandon K. TI Neurotoxic Emergencies SO NEUROLOGIC CLINICS LA English DT Article DE Poisoning; Emergency; Overdose; Neurology; Toxicology ID NEUROLEPTIC MALIGNANT SYNDROME; REFRACTORY STATUS EPILEPTICUS; CONVULSIVE STATUS EPILEPTICUS; GAMMA-HYDROXYBUTYRIC ACID; OF-HOSPITAL MANAGEMENT; CASE SERIES; SEROTONIN SYNDROME; CLINICAL-PHARMACOLOGY; ANTIEPILEPTIC DRUGS; DELIRIUM-TREMENS AB Neurotoxic emergencies are depicted by severe disruption of critical central or peripheral nervous system functions caused by xenobiotics with rapid mechanisms of action. This article reviews 4 categories of neurotoxic emergency: drug-induced and toxin-induced seizures, acute depressed mental status, acute excited mental status, and peripheral neurotoxic agents. Selected xenobiotics, representing the frontiers of neurotoxic emergencies, are discussed in detail based on the major neurotransmitters involved. C1 [Barry, J. Dave] USN, Med Ctr Portsmouth, Emergency Med Residency Program, Portsmouth, VA 23708 USA. [Barry, J. Dave] USN, Med Ctr Portsmouth, Dept Emergency Med, Portsmouth, VA 23708 USA. [Barry, J. Dave] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA. [Wills, Brandon K.] Virginia Commonwealth Univ, Med Ctr, Richmond, VA USA. [Wills, Brandon K.] Virginia Commonwealth Univ, Ctr Hlth, Dept Emergency Med, Richmond, VA USA. [Wills, Brandon K.] Virginia Poison Ctr, Richmond, VA 23298 USA. RP Barry, JD (reprint author), 2605 Admiral Dr, Virginia Beach, VA 23451 USA. EM James.barry@med.navy.mil NR 181 TC 3 Z9 3 U1 0 U2 2 PU W B SAUNDERS CO-ELSEVIER INC PI PHILADELPHIA PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA SN 0733-8619 EI 1557-9875 J9 NEUROL CLIN JI Neurol. Clin. PD AUG PY 2011 VL 29 IS 3 BP 539 EP + DI 10.1016/j.ncl.2011.05.006 PG 26 WC Clinical Neurology; Neurosciences SC Neurosciences & Neurology GA 813NI UT WOS:000294373800002 PM 21803209 ER PT J AU Arvizo, MR Calusdian, J Hollinger, KB Pace, PE AF Arvizo, Mylene R. Calusdian, James Hollinger, Kenneth B. Pace, Phillip E. TI Robust symmetrical number system preprocessing for minimizing encoding errors in photonic analog-to-digital converters SO OPTICAL ENGINEERING LA English DT Article DE analog-to-digital converter; integrated optics; robust symmetrical number systems ID BINARY CONVERSION; MODULATOR; DESIGN; TIME AB A photonic analog-to-digital converter (ADC) preprocessing architecture based on the robust symmetrical number system (RSNS) is presented. The RSNS preprocessing architecture is a modular scheme in which a modulus number of comparators are used at the output of each Mach-Zehnder modulator channel. The number of comparators with a logic 1 in each channel represents the integer values within each RSNS modulus sequence. When considered together, the integers within each sequence change one at a time at the next code position, resulting in an integer Gray code property. The RSNS ADC has the feature that the maximum nonlinearity is less than a least significant bit (LSB). Although the observed dynamic range (greatest length of combined sequences that contain no ambiguities) of the RSNS ADC is less than the optimum symmetrical number system ADC, the integer Gray code properties make it attractive for error control. A prototype is presented to demonstrate the feasibility of the concept and to show the important RSNS property that the largest nonlinearity is always less than a LSB. Also discussed are practical considerations related to multi-gigahertz implementations. (C) 2011 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.3609801] C1 [Arvizo, Mylene R.] USN, Ctr Surface Warfare, Port Hueneme Div, Port Hueneme, CA 93043 USA. [Calusdian, James; Pace, Phillip E.] USN, Postgrad Sch Monterey, Dept Elect & Comp Engn, Opt Elect Lab, Monterey, CA 93943 USA. [Calusdian, James] USN, Control Syst Lab, Postgrad Sch, Monterey, CA 93943 USA. [Hollinger, Kenneth B.] Marine Corps Tact Syst Support Act, Camp Pendleton, CA 92055 USA. RP Arvizo, MR (reprint author), USN, Ctr Surface Warfare, Port Hueneme Div, Port Hueneme, CA 93043 USA. EM pepace@nps.edu FU Office of Naval Research, Code 31, Washington DC FX We wish to thank the reviewers for their very helpful comments that improved the quality of the paper considerably. This work was supported by the Office of Naval Research, Code 31, Washington DC. NR 34 TC 2 Z9 2 U1 3 U2 4 PU SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98225 USA SN 0091-3286 J9 OPT ENG JI Opt. Eng. PD AUG PY 2011 VL 50 IS 8 AR 084602 DI 10.1117/1.3609801 PG 11 WC Optics SC Optics GA 812PX UT WOS:000294306500027 ER PT J AU McIlhany, KL Mott, D Oran, E Wiggins, S AF McIlhany, Kevin L. Mott, David Oran, Elaine Wiggins, Stephen TI Optimizing mixing in lid-driven flow designs through predictions from Eulerian indicators SO PHYSICS OF FLUIDS LA English DT Article ID MICROFLUIDIC COMPONENTS; CHAOTIC ADVECTION; MIXER; MICROMIXERS; TOOLBOX; CHANNEL AB In this paper, we further develop the notion of Eulerian indicators (EIs) for predicting Lagrangian mixing behavior. We employ a two-dimensional "blinking" Stokes flow as a model for mixing in a three-dimensional, spatially periodic channel flow. Each blinking flow alternates two distinct velocity fields that were calculated using a lid-driven cavity model. A new EI termed mobility is introduced to measure how effectively the blinking velocity fields transport fluid throughout the domain. We also calculate the transversality for these flows, which is an EI measuring how much the velocity direction at each point in the domain changes when the velocity fields blink. For the studied flows, we show that although individually the mobility and transversality do not correlate well with mixing as measured by the decay of the variance of concentration, the product of mobility and transversality does correlate well with the decay of the variance of concentration and predicts which combinations of velocity fields will produce the most effective mixing. VC 2011 American Institute of Physics. [doi:10.1063/1.3626022] C1 [McIlhany, Kevin L.] USN Acad, Dept Phys, Annapolis, MD 21402 USA. [Mott, David; Oran, Elaine] USN, Res Lab, Labs Computat Phys & Fluid Dynam, Washington, DC 20375 USA. [Wiggins, Stephen] Univ Bristol, Sch Math, Bristol BS8 1TW, Avon, England. RP McIlhany, KL (reprint author), USN Acad, Dept Phys, Stop 9C,572C Holloway RD, Annapolis, MD 21402 USA. EM mcilhany@usna.edu; mott@lcp.nrl.navy.mil; oran@lcp.nrl.navy.mil; s.wiggins@bristol.ac.uk OI Mott, David/0000-0002-7863-456X FU ONR [N00014-01-1-0769, N00014-09-WR-2-0256, N00014-09-WR-20255, N00014-10-WX-21393] FX The research of S.W. was supported by ONR Grant No. N00014-01-1-0769, the research of K.M. was supported by ONR Grant No. N00014-09-WR-2-0256, and the research of D.M. and E.O. was supported by ONR Grant Nos. N00014-09-WR-20255 and N00014-10-WX-21393. NR 25 TC 5 Z9 5 U1 1 U2 5 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 1070-6631 J9 PHYS FLUIDS JI Phys. Fluids PD AUG PY 2011 VL 23 IS 8 AR 082005 DI 10.1063/1.3626022 PG 13 WC Mechanics; Physics, Fluids & Plasmas SC Mechanics; Physics GA 814UU UT WOS:000294483500009 ER PT J AU Willingale, L Petrov, GM Maksimchuk, A Davis, J Freeman, RR Joglekar, AS Matsuoka, T Murphy, CD Ovchinnikov, VM Thomas, AGR Van Woerkom, L Krushelnick, K AF Willingale, L. Petrov, G. M. Maksimchuk, A. Davis, J. Freeman, R. R. Joglekar, A. S. Matsuoka, T. Murphy, C. D. Ovchinnikov, V. M. Thomas, A. G. R. Van Woerkom, L. Krushelnick, K. TI Comparison of bulk and pitcher-catcher targets for laser-driven neutron production SO PHYSICS OF PLASMAS LA English DT Article ID HIGH-INTENSITY LASER; NUCLEAR-FUSION; ION-BEAMS; TRANSPORT; PLASMA; DEUTERIUM; EMISSION; ELECTRON; PULSES AB Laser-driven d(d, n)-He-3 beam-target fusion neutron production from bulk deuterated plastic (CD) targets is compared with a pitcher-catcher target scheme using an identical laser and detector arrangement. For laser intensities in the range of (1-3) x 10(19) W cm(-2), it was found that the bulk targets produced a high yield (5 x 10(4) neutrons per steradian) beamed preferentially in the laser propagation direction. Numerical modeling shows the importance of considering the temperature adjusted stopping powers to correctly model the neutron production. The bulk CD targets have a high background target temperature leading to a reduced stopping power for the deuterons, which increases the probability of generating neutrons by fusion. Neutron production from the pitcher-catcher targets was not as efficient since it does not benefit from the reduced stopping power in the cold catcher target. Also, the inhibition of the deuteron acceleration by a proton rich contamination layer significantly reduces the pitcher-catcher neutron production. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3624769] C1 [Willingale, L.; Maksimchuk, A.; Joglekar, A. S.; Matsuoka, T.; Thomas, A. G. R.; Krushelnick, K.] Univ Michigan, Ctr Ultrafast Opt Sci, Ann Arbor, MI 48109 USA. [Petrov, G. M.; Davis, J.] USN, Res Lab, Div Plasma Phys, Washington, DC 20375 USA. [Freeman, R. R.; Murphy, C. D.; Ovchinnikov, V. M.; Van Woerkom, L.] Ohio State Univ, Dept Phys, Columbus, OH 43210 USA. RP Willingale, L (reprint author), Univ Michigan, Ctr Ultrafast Opt Sci, 2200 Bonisteel Blvd, Ann Arbor, MI 48109 USA. RI Thomas, Alexander/D-8210-2011; OI Thomas, Alexander/0000-0003-3206-8512 FU Defense Threat Reduction Agency (DTRA); Naval Research Laboratory (NRL) FX This work was supported by the Defense Threat Reduction Agency (DTRA) and the Naval Research Laboratory (NRL). The authors thank Dr. M. R. Hartman for assistance with the d-d neutron generator. NR 37 TC 18 Z9 18 U1 1 U2 14 PU AMER INST PHYSICS PI MELVILLE PA 1305 WALT WHITMAN RD, STE 300, MELVILLE, NY 11747-4501 USA SN 1070-664X EI 1089-7674 J9 PHYS PLASMAS JI Phys. Plasmas PD AUG PY 2011 VL 18 IS 8 AR 083106 DI 10.1063/1.3624769 PG 6 WC Physics, Fluids & Plasmas SC Physics GA 814VX UT WOS:000294486400057 ER PT J AU Sapsford, KE Spindel, S Jennings, T Tao, GL Triulzi, RC Algar, WR Medintz, IL AF Sapsford, Kim E. Spindel, Samantha Jennings, Travis Tao, Guoliang Triulzi, Robert C. Algar, W. Russ Medintz, Igor L. TI Optimizing Two-Color Semiconductor Nanocrystal Immunoassays in Single Well Microtiter Plate Formats SO SENSORS LA English DT Article DE quantum dot (QD); nanocrystal (NC); semiconductor; bioconjugation; sensor; multiplex; immunoassay; sulfhydryl chemistry ID STAPHYLOCOCCAL-ENTEROTOXIN-B; QUANTUM DOTS; MULTIPLEXED DETECTION; CDSE; PROTEINS; ASSAYS; MILK AB The simultaneous detection of two analytes, chicken IgY (IgG) and Staphylococcal enterotoxin B (SEB), in the single well of a 96-well plate is demonstrated using luminescent semiconductor quantum dot nanocrystal (NC) tracers. The NC-labeled antibodies were prepared via sulfhydryl-reactive chemistry using a facile protocol that took <3 h. Dose response curves for each target were evaluated in a single immunoassay format and compared to Cy5, a fluorophore commonly used in fluorescent immunoassays, and found to be equivalent. Immunoassays were then performed in a duplex format, demonstrating multiplex detection in a single well with limits of detection equivalent to the single assay format: 9.8 ng/mL chicken IgG and 7.8 ng/mL SEB. C1 [Sapsford, Kim E.; Spindel, Samantha] US FDA, Div Biol, Off Sci & Engn Labs, Silver Spring, MD 20993 USA. [Spindel, Samantha] Univ Maryland, Fischell Dept Bioengn, College Pk, MD 20993 USA. [Jennings, Travis; Tao, Guoliang; Triulzi, Robert C.] eBioscience Inc, San Diego, CA 92121 USA. [Algar, W. Russ; Medintz, Igor L.] USN, Res Lab, Ctr Biomol Sci & Engn, Washington, DC 20375 USA. [Algar, W. Russ] George Mason Univ, Coll Sci, Fairfax, VA 22030 USA. RP Sapsford, KE (reprint author), US FDA, Div Biol, Off Sci & Engn Labs, 10903 New Hampshire Ave, Silver Spring, MD 20993 USA. EM kim.sapsford@fda.hhs.go; samantha.spindel@fda.hhs.gov; travis.jennings@ebioscience.com; guoliang.tao@ebioscience.com; robert.triulzi@ebioscience.com; russ.algar.ctr.ca@nrl.navy.mil; igor.medintz@nrl.navy.mil FU CB Directorate/Physical S&T Division (DTRA); DARPA; ONR; NRL; NRL-NSI; Critical Path Initiative FX The authors would like to thank Edward Gordon (FDA/CDRH/OSEL/DB) for his assistance taking the digital images of the illuminated NCs in Figure 1. The authors acknowledge the CB Directorate/Physical S&T Division (DTRA), DARPA, ONR, NRL and the NRL-NSI for financial support. K. S. and S. S. acknowledges the Critical Path Initiative for financial support. NR 33 TC 13 Z9 13 U1 0 U2 21 PU MDPI AG PI BASEL PA POSTFACH, CH-4005 BASEL, SWITZERLAND SN 1424-8220 J9 SENSORS-BASEL JI Sensors PD AUG PY 2011 VL 11 IS 8 BP 7879 EP 7891 DI 10.3390/s110807879 PG 13 WC Chemistry, Analytical; Electrochemistry; Instruments & Instrumentation SC Chemistry; Electrochemistry; Instruments & Instrumentation GA 811YE UT WOS:000294253900034 PM 22164051 ER PT J AU Fulmer, PA Wynne, JH AF Fulmer, Preston A. Wynne, James H. TI Development of Broad-Spectrum Antimicrobial Latex Paint Surfaces Employing Active Amphiphilic Compounds SO ACS APPLIED MATERIALS & INTERFACES LA English DT Article DE self-decontaminating surface; antimicrobial; functional coating; latex coatings; quaternary ammonium salt ID SALMONELLA-TYPHIMURIUM; PEPTIDES; ANTIBACTERIAL; EFFICACY; COATINGS; SYSTEMS; BINDING; LIGHT; BIOMATERIALS; COPOLYMERS AB With the increase in antibiotic-resistant microbes, the production of self-decontaminating surfaces has become an area of research that has seen a surge of interest in recent years. Such surfaces, when incorporated into commercial products such as children's toys, medical devices and hospital surfaces could reduce the number of infections caused by pathogenic microorganisms. A number of active components for self-decontaminating surfaces have been investigated, including common antibiotics, metal ions, quaternary ammonium salts (QAS), and antimicrobial peptides (AMP). A recent research focus has been development of a wide range of amphiphilic antimicrobial additives that when combined with modern low volatile organic compound (VOC), water-based paints leads to a surface concentration of the active compounds as the coating cures. Herein we report the development of antimicrobial coatings containing a variety of additives, both QAS and AMP that are active against a broadspectrum of potentially pathogenic bacteria (1-7 log kill), as well as enveloped viruses (2-7 log kill) and fungi (1-2 log kill). Additionally, these additives were compatible with water-dispersed acrylate coatings (latex paint) which have a broad range of real world applicability, and remained active for multiple challenges and when exposed to various cleaning scenarios in which they might encounter in real world situations. C1 [Fulmer, Preston A.; Wynne, James H.] USN, Res Lab, Div Chem, Washington, DC 20375 USA. RP Wynne, JH (reprint author), USN, Res Lab, Div Chem, Code 6100,4555 Overlook Ave SW, Washington, DC 20375 USA. EM james.wynne@nrl.navy.mil RI Fulmer, Preston/L-7702-2014 OI Fulmer, Preston/0000-0002-2981-576X FU Office of Naval Research (ONR); Naval Research Laboratory FX This work was funded by the Office of Naval Research (ONR) and the Naval Research Laboratory. The authors thank Dr. Robert Brizzalera at the Naval Surface Warfare Center-Carderock Division for assistance with XPS analysis. NR 52 TC 20 Z9 20 U1 1 U2 36 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1944-8244 J9 ACS APPL MATER INTER JI ACS Appl. Mater. Interfaces PD AUG PY 2011 VL 3 IS 8 BP 2878 EP 2884 DI 10.1021/am2005465 PG 7 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Science & Technology - Other Topics; Materials Science GA 810SH UT WOS:000294146900010 PM 21770409 ER PT J AU Oh, E Delehanty, JB Sapsford, KE Susumu, K Goswami, R Blanco-Canosa, JB Dawson, PE Granek, J Shoff, M Zhang, Q Goering, PL Huston, A Medintz, IL AF Oh, Eunkeu Delehanty, James B. Sapsford, Kim E. Susumu, Kimihiro Goswami, Ramasis Blanco-Canosa, Juan B. Dawson, Philip E. Granek, Jessica Shoff, Megan Zhang, Qin Goering, Peter L. Huston, Alan Medintz, Igor L. TI Cellular Uptake and Fate of PEGylated Gold Nanoparticles Is Dependent on Both Cell-Penetration Peptides and Particle Size SO ACS NANO LA English DT Article DE gold nanoparticle; cell-penetrating peptide; cellular uptake; cytotoxicity; PEG; surface charge; endotoxin; dual mode fluorescence; silver staining ID NUCLEAR-LOCALIZATION SIGNALS; QUANTUM DOTS; MAMMALIAN-CELLS; MULTIFUNCTIONAL LIGANDS; GENE DELIVERY; PORE COMPLEX; TAT PEPTIDE; STABILITY; FUNCTIONALITIES; ENDOTOXIN AB Numerous studies have examined how the cellular delivery of gold nanoparticles (AuNPs) is influenced by different physical and chemical characteristics; however, the complex relationship. between AuNP size, uptake efficiency, and intracellular localization remains only partially understood. Here we examine the cellular uptake of a series of AuNPs ranging in diameter from 2.4 to 89 nm that are synthesized and made soluble with poly(ethylene glycol)-functionalized dithiolane ligands terminating in either carboxyl or methoxy groups and covalently conjugated to cell penetrating peptides. Following synthesis, extensive physical characterization of the AuNPs was performed with UV-vis absorption, gel electrophoresis, zeta potential, dynamic light scattering, and high resolution transmission electron microscopy. Uptake efficiency and intracellular localization of the AuNP-peptide conjugates In a model COS-1 cell line were probed with a combination of silver staining, fluorescent counterstaining, and dual mode fluorescence coupled to nonfluorescent scattering. Our findings show that AuNP cellular uptake Is directly dependent on the surface display of the cell-penetrating peptide and that the ultimate intracellular destination is further determined by AuNP diameter. The smallest 2.4 nm AuNPs were found to localize in the nucleus, while intermediate 5.5 and 8.2 nm particles were partially delivered into the cytoplasm, showing a. primarily perinuclear fate along with a portion of the nanoparticles appearing to remain at the membrane. The 16 nm and larger AuNPs did not enter the cells and were located at the cellular periphery. A preliminary assessment of cytotoxicity demonstrated minimal effects on cellular viability following peptide-mediated uptake. C1 [Oh, Eunkeu; Susumu, Kimihiro; Huston, Alan] USN, Res Lab, Opt Sci Div, Washington, DC 20375 USA. [Delehanty, James B.; Medintz, Igor L.] USN, Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. [Goswami, Ramasis] USN, Res Lab, Nanosci Inst, Washington, DC 20375 USA. [Sapsford, Kim E.; Granek, Jessica; Shoff, Megan; Zhang, Qin; Goering, Peter L.] US FDA, Div Biol, Off Sci & Engn Labs, Silver Spring, MD 20993 USA. [Blanco-Canosa, Juan B.; Dawson, Philip E.] Scripps Res Inst, Dept Cell Biol, La Jolla, CA 92037 USA. [Blanco-Canosa, Juan B.; Dawson, Philip E.] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA. RP Oh, E (reprint author), USN, Res Lab, Opt Sci Div, Washington, DC 20375 USA. EM Eunkeuoh@ccs.nrl.navy.mil; Igor.Medintz@nrl.navy.mil FU NRL; NRL NSI; ONR; DTRA/ARO; DARPA; FDA [HHSF223200610765P] FX The authors acknowledge NRL, the NRL NSI, ONR, DTRA/ARO, DARPA, and FDA Contract HHSF223200610765P for financial support. J.B.B.-C. acknowledges a Marie Curie IOF. NR 70 TC 154 Z9 160 U1 17 U2 239 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1936-0851 EI 1936-086X J9 ACS NANO JI ACS Nano PD AUG PY 2011 VL 5 IS 8 BP 6434 EP 6448 DI 10.1021/nn201624c PG 15 WC Chemistry, Multidisciplinary; Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Chemistry; Science & Technology - Other Topics; Materials Science GA 809VS UT WOS:000294085400043 PM 21774456 ER PT J AU Ma, C Connolly, HC Beckett, JR Tschauner, O Rossman, GR Kampf, AR Zega, TJ Smith, SAS Schrader, DL AF Ma, Chi Connolly, Harold C., Jr. Beckett, John R. Tschauner, Oliver Rossman, George R. Kampf, Anthony R. Zega, Thomas J. Smith, Stuart A. Sweeney Schrader, Devin L. TI Brearleyite, Ca12Al14O32Cl2, a new alteration mineral from the NWA 1934 meteorite SO AMERICAN MINERALOGIST LA English DT Article DE Brearleyite; Ca12Al14O32Cl2; new mineral; Cl-bearing mayenite; NWA 1934 meteorite; CV3 carbonaceous chondrite; SAED ring pattern; Rietveld refinement ID POWDER DIFFRACTION; ALLENDE METEORITE; INCLUSION; PATTERNS; MAYENITE; HISTORY AB Brearleyite (IMA 2010-062, Ca12Al14O32Cl2) is a Cl-bearing mayenite, occurring as fine-grained aggregates coexisting with hercynite, gehlenite, and perovskite in a rare krotite (CaAl2O4) dominant refractory inclusion from the Northwest Africa 1934 CV3 carbonaceous chondrite. The phase was characterized by SEM, TEM-SAED, micro-Raman, and EPMA. The mean chemical composition of the brearleyite is (wt%) Al2O3 48.48, CaO 45.73, Cl 5.12, FeO 0.80, Na2O 0.12, TiO2 0.03, -O 1.16, sum 99.12. The corresponding empirical formula calculated on the basis of 34 O+Cl atoms is (Ca-11.91 Na-0.06)(Sigma 11.97)(Al13.89Fe0.16Ti0.01)(Sigma 14.06)O31.89Cl2.11. The Raman spectrum of brealryeite indicates very close structural similarity to synthetic Ca12Al14O32Cl2. Rietveld refinement of an integrated TEM-SAED ring pattern from a FIB section quantifies this structural relationship and indicates that brearleyite is cubic, I (4) over bar 3d; a = 11.98(8) angstrom, V = 1719.1(2) angstrom(3), and Z = 2. It has a framework structure in which AlO4 tetrahedra share corners to form eight-membered rings. Within this framework, the Cl atom is located at a special position (3/8,0.1/4) with 0.4(2) occupancy and Ca appears to be disordered on two partially occupied sites similar to synthetic Cl-mayenite. Brearleyite has a light olive color under diffuse reflected light and a calculated density of 2.797 g/cm(3). Brearleyite is not only a new meteoritic Ca-,Al-phase, but also a new meteoritic Cl-rich phase. It likely formed by the reaction of krotite with Cl-bearing hot gases or fluids. C1 [Ma, Chi; Beckett, John R.; Tschauner, Oliver; Rossman, George R.] CALTECH, Div Geol & Planetary Sci, Pasadena, CA 91125 USA. [Connolly, Harold C., Jr.] CUNY, Kingsborough Community Coll, Dept Phys Sci, Brooklyn, NY 11235 USA. [Connolly, Harold C., Jr.] CUNY, Grad Ctr, New York, NY 10024 USA. [Connolly, Harold C., Jr.; Smith, Stuart A. Sweeney] Amer Museum Nat Hist, Dept Earth & Planetary Sci, New York, NY 10024 USA. [Connolly, Harold C., Jr.; Schrader, Devin L.] Univ Arizona, Lunar & Planetary Lab, Tucson, AZ 85721 USA. [Tschauner, Oliver] Univ Nevada, High Pressure Sci & Engn Ctr, Las Vegas, NV 89154 USA. [Tschauner, Oliver] Univ Nevada, Dept Geosci, Las Vegas, NV 89154 USA. [Kampf, Anthony R.] Nat Hist Museum Los Angeles Cty, Dept Mineral Sci, Los Angeles, CA 90007 USA. [Zega, Thomas J.] USN, Mat Sci & Technol Div, Res Lab, Washington, DC 20375 USA. [Smith, Stuart A. Sweeney] Carleton Coll, Dept Geol, Northfield, MN 55057 USA. RP Ma, C (reprint author), CALTECH, Div Geol & Planetary Sci, Pasadena, CA 91125 USA. EM chi@gps.caltech.edu RI Schrader, Devin/H-6293-2012; OI Schrader, Devin/0000-0001-5282-232X; Rossman, George/0000-0002-4571-6884 FU NSF [EAR-0318518, DMR-0080065, AST 0851362, EAR-0337816]; NASA [NNX09AB86G, NNX09AG40G, NNH09AK541]; NNSA [DE-FC88-01NVI4049] FX SEM, EBSD, and EPMA analyses were carried out at the Caltech GPS Division Analytical Facility, which is supported, in part, by grant NSF EAR-0318518 and the MRSEC Program of the NSF under DMR-0080065. FIB and TEM work was performed at the Naval Research Laboratory. This research was also supported by NSF REU grant AST 0851362 and NASA OSS Grant NNX09AB86G (to H.C.C. Jr.), NNX09AG40G (to E.M Stolper), and NNH09AK541 (to T.J.Z.), and NSF grant EAR-0337816 (to G.R.R.), and NNSA Cooperative Agreement DE-FC88-01NVI4049 (to O.T.). We thank Colombo, C.M. Gramaecioli, and J.C. Melgarejo for constructive reviews of this manuscript. NR 28 TC 12 Z9 13 U1 1 U2 28 PU MINERALOGICAL SOC AMER PI CHANTILLY PA 3635 CONCORDE PKWY STE 500, CHANTILLY, VA 20151-1125 USA SN 0003-004X J9 AM MINERAL JI Am. Miner. PD AUG-SEP PY 2011 VL 96 IS 8-9 BP 1199 EP 1206 DI 10.2138/am.2011.3755 PG 8 WC Geochemistry & Geophysics; Mineralogy SC Geochemistry & Geophysics; Mineralogy GA 808QM UT WOS:000293993500002 ER PT J AU Cole, S Kearns, D Magit, A AF Cole, Stephanie Kearns, Donald Magit, Anthony TI Chronic Esophageal Foreign Bodies and Secondary Mediastinitis in Children SO ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY LA English DT Article DE complication; esophageal foreign body; mediastinitis; treatment ID NONOPERATIVE MANAGEMENT; BODY AB Objectives: The purpose of this study was to review the clinical presentation, diagnosis, and management of chronic esophageal foreign bodies complicated by mediastinitis in children. Methods: A retrospective study of children with a chronic esophageal foreign body and secondary mediastinal complications diagnosed at Rady Children's Hospital in San Diego over a 12-month period is reported. Results: Three patients received a diagnosis of an esophageal foreign body, retained from 1 to 12 months, and mediastinitis. Each patient presented primarily with respiratory signs and had been treated previously for alternate diagnoses (ie, asthma, reflux, and upper respiratory tract infection) by emergency or pediatric providers. The diagnosis of a foreign body was made after a chest radiograph was examined. Operative airway evaluation confirmed tracheal narrowing in all patients, and a computed tomographic scan of the chest was performed after removal of the foreign body to confirm mediastinal involvement. After medical and/or surgical treatment, the patients were released from the hospital tolerating soft diets. There were no reports of long-term complications in our series of patients. Conclusions: It is critical to rule out esophageal and airway foreign bodies in pediatric patients with respiratory symptoms that do not respond to medical treatment. Timely recognition of an esophageal foreign body generally allows for removal with minimal morbidity, whereas the incidence of serious complications increases significantly when the diagnosis is delayed. Our series provides support for conservative management of mediastinal complications after removal of chronically retained esophageal foreign bodies in children. C1 [Cole, Stephanie] USN, San Diego Med Ctr, Dept Otolaryngol, San Diego, CA USA. [Kearns, Donald; Magit, Anthony] Rady Childrens Hosp, Dept Otolaryngol, San Diego, CA USA. RP Cole, S (reprint author), 100 Brewster Blvd, Camp Lejeune, NC 28547 USA. NR 15 TC 1 Z9 1 U1 0 U2 3 PU ANNALS PUBL CO PI ST LOUIS PA 4507 LACLEDE AVE, ST LOUIS, MO 63108 USA SN 0003-4894 J9 ANN OTO RHINOL LARYN JI Ann. Otol. Rhinol. Laryngol. PD AUG PY 2011 VL 120 IS 8 BP 542 EP 545 PG 4 WC Otorhinolaryngology SC Otorhinolaryngology GA 812EG UT WOS:000294273300009 PM 21922979 ER PT J AU Wittkowski, M Boboltz, DA Ireland, M Karovicova, I Ohnaka, K Scholz, M van Wyk, F Whitelock, P Wood, PR Zijlstra, AA AF Wittkowski, M. Boboltz, D. A. Ireland, M. Karovicova, I. Ohnaka, K. Scholz, M. van Wyk, F. Whitelock, P. Wood, P. R. Zijlstra, A. A. TI Inhomogeneities in molecular layers of Mira atmospheres SO ASTRONOMY & ASTROPHYSICS LA English DT Article DE techniques: interferometric; techniques: photometric; stars: AGB and post-AGB; stars: atmospheres; stars: fundamental parameters; stars: mass-loss ID GIANT BRANCH STARS; DATA REDUCTION; VARIABLES; INTERFEROMETRY; AMBER/VLTI; INSTRUMENT; PULSATION; MODELS AB Aims. We investigate the structure and shape of the photospheric and molecular layers of the atmospheres of four Mira variables. Methods. We obtained near-infrared K-band spectro-interferometric observations of the Mira variables R Cnc, X Hya, W Vel, and RW Vel with a spectral resolution of about 1500 using the AMBER instrument at the VLTI. We obtained concurrent JHKL photometry using the the Mk II instrument at the SAAO. Results. The Mira stars in our sample are found to have wavelength-dependent visibility values that are consistent with earlier low-resolution AMBER observations of S Ori and with the predictions of dynamic model atmosphere series based on self-excited pulsation models. The corresponding wavelength-dependent uniform disk (UD) diameters show a minimum near the near-continuum bandpass at 2.25 mu m. They then increase by up to 30% toward the H2O band at 2.0 mu m and by up to 70% at the CO bandheads between 2.29 mu m and 2.48 mu m. The dynamic model atmosphere series show a consistent wavelength-dependence, and their parameters such as the visual phase, effective temperature, and distances are consistent with independent estimates. The closure phases have significantly wavelength-dependent and non-zero values at all wavelengths indicating deviations from point symmetry. For example, the R Cnc closure phase is 110 degrees +/- 4 degrees in the 2.0 mu m H2O band, corresponding for instance to an additional unresolved spot contributing 3% of the total flux at a separation of similar to 4 mas. Conclusions. Our observations are consistent with the predictions of the latest dynamic model atmosphere series based on self-excited pulsation models. The wavelength-dependent radius variations are interpreted as the effect of molecular layers lying above the photosphere. The wavelength-dependent closure phase values are indicative of deviations from point symmetry at all wavelengths, thus a complex non-spherical stratification of the extended atmosphere. In particular, the significant deviation from point symmetry in the H2O band is interpreted as a signature on large scales (there being a few across the stellar disk) of inhomogeneities or clumps in the water vapor layer. The observed inhomogeneities might possibly be caused by pulsation-and shock-induced chaotic motion in the extended atmosphere. C1 [Wittkowski, M.; Karovicova, I.] ESO, D-85748 Garching, Germany. [Boboltz, D. A.] USN Observ, Washington, DC 20392 USA. [Ireland, M.] Macquarie Univ, Dept Phys & Astron, N Ryde, NSW 2109, Australia. [Ireland, M.] Australian Astron Observ, Epping, NSW 1710, Australia. [Ohnaka, K.] Max Planck Inst Radioastron, D-53121 Bonn, Germany. [Scholz, M.] Heidelberg Univ, Zentrum Astron, Inst Theoret Astrophys, D-69120 Heidelberg, Germany. [Scholz, M.] Univ Sydney, Sch Phys, Sydney Inst Astron, Sydney, NSW 2006, Australia. [van Wyk, F.; Whitelock, P.] SAAO, ZA-7935 Observatory, South Africa. [Whitelock, P.] Univ Cape Town, Dept Astron, Astrophys Cosmol & Gravitat Ctr, ZA-7701 Rondebosch, South Africa. [Wood, P. R.] Australian Natl Univ, Res Sch Astron & Astrophys, Canberra, ACT, Australia. [Zijlstra, A. A.] Univ Manchester, Sch Phys & Astron, Manchester M60 1QD, Lancs, England. RP Wittkowski, M (reprint author), ESO, Karl Schwarzschild Str 2, D-85748 Garching, Germany. EM mwittkow@eso.org OI Wittkowski, Markus/0000-0002-7952-9550 NR 23 TC 34 Z9 34 U1 1 U2 4 PU EDP SCIENCES S A PI LES ULIS CEDEX A PA 17, AVE DU HOGGAR, PA COURTABOEUF, BP 112, F-91944 LES ULIS CEDEX A, FRANCE SN 0004-6361 J9 ASTRON ASTROPHYS JI Astron. Astrophys. PD AUG PY 2011 VL 532 AR L7 DI 10.1051/0004-6361/201117411 PG 5 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 799JS UT WOS:000293283600009 ER PT J AU Tait, GB Richardson, RE Slocum, MB Hatfield, MO AF Tait, Gregory B. Richardson, Robert E. Slocum, Michael B. Hatfield, Michael O. TI Time-Dependent Model of RF Energy Propagation in Coupled Reverberant Cavities SO IEEE TRANSACTIONS ON ELECTROMAGNETIC COMPATIBILITY LA English DT Article DE Coupled cavities; reverberant energy propagation AB A simple time-dependent model for the analysis of RF energy propagation in coupled reverberant cavities is presented. The cumulative buildup and full exchange of radiated electromagnetic energy between coupled spaces are important issues for electronic systems compatibility in reverberant environments such as below-deck compartments in ships and aircraft cabins and bays. Based on conservation of average energy, the general model formulation is valid for both weak and strong couplings between the cavities caused by window materials, open apertures, closed and open hatches, seams, and cable/pipe penetrations through bulkheads. Application of the model is demonstrated using time-resolved received power measurements conducted in nested reverberation chambers. C1 [Tait, Gregory B.; Richardson, Robert E.; Slocum, Michael B.; Hatfield, Michael O.] USN, Ctr Surface Warfare, Dahlgren, VA 22448 USA. RP Tait, GB (reprint author), USN, Ctr Surface Warfare, Dahlgren, VA 22448 USA. NR 11 TC 8 Z9 8 U1 0 U2 1 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0018-9375 J9 IEEE T ELECTROMAGN C JI IEEE Trans. Electromagn. Compat. PD AUG PY 2011 VL 53 IS 3 BP 846 EP 849 DI 10.1109/TEMC.2011.2150228 PG 4 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA 810NJ UT WOS:000294131700034 ER PT J AU Gao, JQ Zhai, JY Shen, Y Shen, LG Gray, D Li, JF Finkel, P Viehland, D AF Gao, Junqi Zhai, Junyi Shen, Ying Shen, Liangguo Gray, David Li, Jiefang Finkel, Peter Viehland, D. TI Differential-Mode Vibrational Noise Cancellation Structure for Metglas/Pb(Zr,Ti)O-3 Fiber Magnetoelectric Laminates SO IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL LA English DT Article AB A differential structure which has the ability to reject external vibrational noise for Metglas/Pb(Zr, Ti)O-3 (PZT) fiber-based magnetoelectric (ME) heterostructures has been studied. This type of ME structure functions better than conventional sensors as a magnetic sensor when used in an environment in which vibrational isolation is impractical. Sensors fabricated with this differential mode structure can attenuate external vibrational noise by about 10 to 20 dB at different frequencies, while simultaneously having a doubled ME voltage coefficient. Interestingly, in addition to offering a means of mitigating vibrational noise, this ME structure offers the potential to be a hybrid sensor, separating magnetic and acoustical signals. C1 [Gao, Junqi; Zhai, Junyi; Shen, Ying; Shen, Liangguo; Gray, David; Li, Jiefang; Viehland, D.] Virginia Tech, Dept Mat Sci & Engn, Blacksburg, VA 24061 USA. [Finkel, Peter] USN, Undersea Warfare Ctr, Newport, RI USA. RP Gao, JQ (reprint author), Virginia Tech, Dept Mat Sci & Engn, Blacksburg, VA 24061 USA. EM junqi08@vt.edu RI Gao, Junqi/F-2989-2012; Zhai, Junyi/K-4162-2014 FU DARPA; ONR FX Manuscript received February 3, 2011; accepted June 3, 2011. The authors would like to thank DARPA and ONR for support of this work. NR 13 TC 7 Z9 7 U1 0 U2 22 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0885-3010 J9 IEEE T ULTRASON FERR JI IEEE Trans. Ultrason. Ferroelectr. Freq. Control PD AUG PY 2011 VL 58 IS 8 BP 1541 EP 1544 DI 10.1109/TUFFC.2011.1980 PG 4 WC Acoustics; Engineering, Electrical & Electronic SC Acoustics; Engineering GA 811AY UT WOS:000294175100003 PM 21859572 ER PT J AU Gao, JQ Shen, Y Wang, YJ Finkel, P Li, JF Viehland, D AF Gao, Junqi Shen, Ying Wang, Yaojin Finkel, Peter Li, Jiefang Viehland, Dwight TI Magnetoelectric Bending-Mode Structure Based on Metglas/Pb(Zr,Ti)O-3 Fiber Laminates SO IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL LA English DT Article AB A magnetoelectric (ME) bending-mode structure based on Metglas/Pb(Zr,Ti)O-3 fiber laminates has been studied. This bending mode had a fundamental resonance (FBR) of about 210 Hz, which was much lower than that of the longitudinal mode. Near the FBR, the ME voltage coefficient was about 400 V/cm.Oe. Magnetic sensors based on this bending mode had an equivalent magnetic noise floor of <= 0.3 pT/root Hz at f = 210 Hz. C1 [Gao, Junqi; Shen, Ying; Wang, Yaojin; Li, Jiefang; Viehland, Dwight] Virginia Polytech Inst & State Univ, Dept Mat Sci & Engn, Blacksburg, VA 24061 USA. [Finkel, Peter] USN, Undersea Warfare Ctr, Devices Sensors & Mat R&D Branch, Newport, RI USA. RP Gao, JQ (reprint author), Virginia Polytech Inst & State Univ, Dept Mat Sci & Engn, Blacksburg, VA 24061 USA. EM junqi08@vt.edu RI Gao, Junqi/F-2989-2012; Wang, Yaojin/F-3748-2012 OI Wang, Yaojin/0000-0003-2561-1855 FU Defense Advanced Research Projects Agency (DARPA); Office of Naval Research (ONR) FX Manuscript received April 12, 2011; accepted June 13, 2011. The authors thank the Defense Advanced Research Projects Agency (DARPA) and the Office of Naval Research (ONR) for support of this work. NR 13 TC 12 Z9 12 U1 1 U2 25 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0885-3010 J9 IEEE T ULTRASON FERR JI IEEE Trans. Ultrason. Ferroelectr. Freq. Control PD AUG PY 2011 VL 58 IS 8 BP 1545 EP 1549 DI 10.1109/TUFFC.2011.1981 PG 5 WC Acoustics; Engineering, Electrical & Electronic SC Acoustics; Engineering GA 811AY UT WOS:000294175100004 PM 21859573 ER PT J AU Verdeli, H Baily, C Vousoura, E Belser, A Singla, D Manos, G AF Verdeli, Helen Baily, Charles Vousoura, Eleni Belser, Alexander Singla, Daisy Manos, Gail TI The Case for Treating Depression in Military Spouses SO JOURNAL OF FAMILY PSYCHOLOGY LA English DT Article DE military spouses; depression; service members; deployment ID MENTAL-HEALTH PROBLEMS; POSTTRAUMATIC-STRESS-DISORDER; OPERATION DESERT-STORM; FAMILY SYNDROME; SOCIAL SUPPORT; DEPLOYMENT; CHILDREN; COMBAT; IRAQ; CARE AB The increased operational tempo associated with current deployments to Operation Iraqi Freedom (OIF) and Operation Enduring Freedom (OEF) is placing considerable strain on military families Among other sequelae of OIF and OEF deployment, findings from recent studies suggest high rates of depression in spouses of service members. This review presents a rationale for targeting depression among military spouses. It examines how stressors relating to the deployment cycle may contribute to depression in spouses and outlines the effects of spousal depression on the mental health of service members and their children. Mental health services currently available to military spouses as well as barriers to their care are also described. Considerations for the adaptation of treatment to their unique circumstances and needs are discussed. C1 [Verdeli, Helen; Baily, Charles; Vousoura, Eleni; Belser, Alexander] Columbia Univ, Teachers Coll, Dept Counseling & Clin Psychol, New York, NY 10027 USA. [Verdeli, Helen] Columbia Univ, Coll Phys & Surg, New York, NY 10027 USA. [Singla, Daisy] McGill Univ, Dept Psychol, Montreal, PQ, Canada. [Manos, Gail] USN, Med Ctr Portsmouth, Portsmouth, VA USA. RP Verdeli, H (reprint author), Columbia Univ, Teachers Coll, Dept Counseling & Clin Psychol, 525 W 120th St, New York, NY 10027 USA. EM hv2009@columbia.edu RI Vousoura, Eleni/M-2639-2016 OI Vousoura, Eleni/0000-0002-3212-8207 FU NIMH NIH HHS [MH071530, K23 MH071530-01A1, K23 MH071530] NR 83 TC 14 Z9 14 U1 2 U2 9 PU AMER PSYCHOLOGICAL ASSOC PI WASHINGTON PA 750 FIRST ST NE, WASHINGTON, DC 20002-4242 USA SN 0893-3200 J9 J FAM PSYCHOL JI J. Fam. Psychol. PD AUG PY 2011 VL 25 IS 4 BP 488 EP 496 DI 10.1037/a0024525 PG 9 WC Psychology, Clinical; Family Studies SC Psychology; Family Studies GA 809TB UT WOS:000294078500005 PM 21842994 ER PT J AU Mansfield, AJ Bender, RH Hourani, LL Larson, GE AF Mansfield, Alyssa J. Bender, Randall H. Hourani, Laurel L. Larson, Gerald E. TI Suicidal or Self-Harming Ideation in Military Personnel Transitioning to Civilian Life SO SUICIDE AND LIFE-THREATENING BEHAVIOR LA English DT Article ID POSTTRAUMATIC-STRESS-DISORDER; MENTAL-HEALTH PROBLEMS; STUDIES-DEPRESSION SCALE; SUBSTANCE USE DISORDERS; PSYCHOMETRIC PROPERTIES; MAJOR DEPRESSION; VIETNAM VETERANS; PTSD CHECKLIST; PRIMARY-CARE; FIT INDEXES AB Suicides have markedly increased among military personnel in recent years. We used path analysis to examine factors associated with suicidal/self-harming ideation among male Navy and Marine Corps personnel transitioning to civilian life. Roughly 7% of men (Sailors = 5.3%, Marines = 9.0%) reported ideation during the previous 30 days. Results suggest that combat exposure, substance abuse, and resilience are associated with suicidal ideation/self-harming thoughts through the mediation of posttraumatic stress disorder symptoms and/or depression symptoms. Substance abuse plays a moderating role. Resilience had a direct effect only among the Marines. Implications for improving the transition to civilian life are discussed. C1 [Mansfield, Alyssa J.; Bender, Randall H.; Hourani, Laurel L.] RTI Int, Res Triangle Pk, NC 27709 USA. [Mansfield, Alyssa J.] Vet Hlth Adm, Natl Ctr PTSD, Pacific Isl Div, Honolulu, HI USA. [Larson, Gerald E.] USN, Hlth Res Ctr, San Diego, CA 92152 USA. RP Hourani, LL (reprint author), RTI Int, 3040 Cornwallis Rd,POB 12194, Res Triangle Pk, NC 27709 USA. EM hourani@rti.org NR 71 TC 10 Z9 10 U1 7 U2 19 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0363-0234 EI 1943-278X J9 SUICIDE LIFE-THREAT JI Suicide Life-Threat. Behav. PD AUG PY 2011 VL 41 IS 4 BP 392 EP 405 DI 10.1111/j.1943-278X.2011.00039.x PG 14 WC Psychiatry; Psychology, Multidisciplinary SC Psychiatry; Psychology GA 810VX UT WOS:000294157200004 PM 21599725 ER PT J AU Sampson, CR Kaplan, J Knaff, JA DeMaria, M Sisko, CA AF Sampson, Charles R. Kaplan, John Knaff, John A. DeMaria, Mark Sisko, Chris A. TI A Deterministic Rapid Intensification Aid SO WEATHER AND FORECASTING LA English DT Article ID TROPICAL CYCLONE INTENSITY; WINDS; DECAY; MODEL; PERFORMANCE; FORECASTS; LANDFALL; SYSTEM AB Rapid intensification (RI) is difficult to forecast, but some progress has been made in developing probabilistic guidance for predicting these events. One such method is the RI index. The RI index is a probabilistic text product available to National Hurricane Center (NHC) forecasters in real time. The RI index gives the probabilities of three intensification rates [25, 30, and 35 kt (24 h)(-1); or 12.9, 15.4, and 18.0 m s(-1) (24 h)(-1)] for the 24-h period commencing at the initial forecast time. In this study the authors attempt to develop a deterministic intensity forecast aid from the RI index and, then, implement it as part of a consensus intensity forecast (arithmetic mean of several deterministic intensity forecasts used in operations) that has been shown to generally have lower mean forecast errors than any of its members. The RI aid is constructed using the highest available RI index intensification rate available for probabilities at or above a given probability (i.e., a probability threshold). Results indicate that the higher the probability threshold is, the better the RI aid performs. The RI aid appears to outperform the consensus aids at about the 50% probability threshold. The RI aid also improves forecast errors of operational consensus aids starting with a probability threshold of 30% and reduces negative biases in the forecasts. The authors suggest a 40% threshold for producing the RI aid initially. The 40% threshold is available for approximately 8% of all verifying forecasts, produces approximately 4% reduction in mean forecast errors for the intensity consensus aids, and corrects the negative biases by approximately 15%-20%. In operations, the threshold could be moved up to maximize gains in skill (reducing availability) or moved down to maximize availability (reducing gains in skill). C1 [Sampson, Charles R.] USN, Res Lab, Monterey, CA 93943 USA. [Kaplan, John] NOAA, AOML, Hurricane Res Div, Miami, FL USA. [Knaff, John A.; DeMaria, Mark] NOAA, NESDIS, Ft Collins, CO USA. [Sisko, Chris A.] Natl Hurricane Ctr, Miami, FL USA. RP Sampson, CR (reprint author), USN, Res Lab, 7 Grace Hopper Ave,Stop 2, Monterey, CA 93943 USA. EM sampson@nrlmry.navy.mil RI DeMaria, Mark/F-5583-2010; Knaff, John /F-5599-2010; Kaplan, John/A-8709-2014 OI Knaff, John /0000-0003-0427-1409; Kaplan, John/0000-0002-7253-3039 FU NOAA [NA09AANWG0149] FX The authors would like to acknowledge Ann Schrader for her work with the ATCF. The authors also wish to acknowledge John Cook, Ted Tsui, Simon Chang, Chris Landsea, Stacy Stewart, Andrea Schumacher, and two anonymous reviewers for their comments and suggestions. This project is supported through a grant from the NOAA Hurricane Forecast Improvement Project (NA09AANWG0149). The views, opinions, and findings contained in this report are those of the authors and should not be construed as an official National Oceanic and Atmospheric Administration or U.S. government position, policy, or decision. NR 18 TC 7 Z9 7 U1 0 U2 2 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 USA SN 0882-8156 J9 WEATHER FORECAST JI Weather Forecast. PD AUG PY 2011 VL 26 IS 4 BP 579 EP 585 DI 10.1175/WAF-D-10-05010.1 PG 7 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA 811VL UT WOS:000294244200012 ER PT J AU Chen, JY Collins, GT Levant, B Woods, J Deschamps, JR Wang, SM AF Chen, Jianyong Collins, Gregory T. Levant, Beth Woods, James Deschamps, Jeffrey R. Wang, Shaomeng TI CJ-1639: A Potent and Highly Selective Dopamine D3 Receptor Full Agonist SO ACS MEDICINAL CHEMISTRY LETTERS LA English DT Article DE Dopamine receptors; ligands; agonists; drug abuse ID FUNCTIONALIZED LINKING CHAINS; ABUSE THERAPEUTIC AGENTS; D-3 RECEPTOR; HIGH-AFFINITY; ANTAGONISTS; RATS; HYPOTHERMIA; BEHAVIOR; LIGANDS; DESIGN AB We have identified several ligands with high binding affinities to the dopamine D3 receptor and excellent selectivity over the D2 and D1 receptors. CJ-1639 (17) binds to the D3 receptor with a K(i) value of 0.50 nM and displays a selectivity of >5000 times over D2 and D1 receptors in binding assays using dopamine receptors expressed in the native rat brain tissues. CJ-1639 binds to human D3 receptor with a Ki value of 3.61 nM and displays over >1000-fold selectivity over human D1 and D2 receptors. CJ-1639 is active at 0.01 mg/kg at the dopamine D3 receptor in the rat and only starts to show a modest D2 activity at doses as high as 10 mg/kg. CJ-1639 is the most potent and selective D3 full agonist reported to date. C1 [Collins, Gregory T.; Woods, James; Wang, Shaomeng] Univ Michigan, Dept Pharmacol, Ann Arbor, MI 48109 USA. [Chen, Jianyong] Univ Michigan, Dept Internal Med, Ann Arbor, MI 48109 USA. [Wang, Shaomeng] Univ Michigan, Dept Med Chem, Ann Arbor, MI 48109 USA. [Levant, Beth] Univ Kansas, Med Ctr, Dept Pharmacol Toxicol & Therapeut, Kansas City, KS 66160 USA. [Deschamps, Jeffrey R.] USN, Ctr Biomol Sci & Engn, Res Lab, Washington, DC 20375 USA. RP Wang, SM (reprint author), Univ Michigan, Dept Pharmacol, 1500 E Med Ctr Dr, Ann Arbor, MI 48109 USA. EM shaomeng@umich.edu RI Collins, Gregory/K-3125-2012; OI Deschamps, Jeffrey/0000-0001-5845-0010 FU NIDA, NIH [R01DA020669, NIDA Y1-DA-0101]; NIDA [Y1-DA-1101] FX This work was supported by a grant from the NIDA, NIH (R01DA020669). Crystallographic studies were supported by a grant from NIDA under contract Y1-DA-1101. We are grateful to the Addiction Treatment Discovery Programs at the NIDA, NIH, for evaluation of CJ-1639 for its binding affinities and functional activity in cells transfected with cloned human dopamine receptors under the contract NIDA Y1-DA-0101, performed by Dr. Aaron Janowsky at the Oregon Health & Science University (Portland, Oregon). NR 20 TC 10 Z9 10 U1 0 U2 5 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1948-5875 J9 ACS MED CHEM LETT JI ACS Med. Chem. Lett. PD AUG PY 2011 VL 2 IS 8 BP 620 EP 625 DI 10.1021/ml200100t PG 6 WC Chemistry, Medicinal SC Pharmacology & Pharmacy GA 809SB UT WOS:000294075900012 PM 22125662 ER PT J AU Wong, JH Peterson, MS AF Wong, Jason H. Peterson, Matthew S. TI The interaction between memorized objects and abrupt onsets in oculomotor capture SO ATTENTION PERCEPTION & PSYCHOPHYSICS LA English DT Article DE Oculomotor capture; Visual object working memory; Abrupt onsets; Saccade programming ID TOP-DOWN GUIDANCE; WORKING-MEMORY; VISUAL-SEARCH; ATTENTIONAL CAPTURE; COMPETITIVE INTEGRATION; DRIVEN; SELECTION; MODEL; EYES AB Recent evidence has been found for a source of task-irrelevant oculomotor capture (defined as when a salient event draws the eyes away from a primary task) that originates from working memory. An object memorized for a nonsearch task can capture the eyes during search. Here, an experiment was conducted that generated interactions between the presence of a memorized object (a colored disk) with the abrupt onset of a new object during visual search. The goal was to compare memory-driven oculomotor capture to oculomotor capture caused by an abrupt onset. This has implications for saccade programming theories, which have little to say about saccades that are influenced by object working memory. Results showed that memorized objects capture the eyes at nearly the same rate as abrupt onsets. When the abrupt onset and a memorized color coincide in the same object, this combination leads to even greater oculomotor capture. Finally, latencies support the competitive integration model: Shorter saccade latencies were found when the memorized color combined with the onset captured the eyes, as compared to either color or onset only. Longer latencies were also found when the color and onset occurred in the same display but were spatially separated. C1 [Wong, Jason H.; Peterson, Matthew S.] George Mason Univ, Fairfax, VA 22030 USA. RP Wong, JH (reprint author), USN, Undersea Warfare Ctr, 1176 Howell St,B1171-2, Newport, RI 02841 USA. EM wongjasonh@gmail.com FU Department of Defense FX The authors thank our lab members for helpful comments on the manuscript. This work was adapted from a portion of J.H.W.'s doctoral dissertation at George Mason University and was funded by a Department of Defense SMART scholarship to J.H.W. NR 23 TC 6 Z9 6 U1 0 U2 3 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1943-3921 J9 ATTEN PERCEPT PSYCHO JI Atten. Percept. Psychophys. PD AUG PY 2011 VL 73 IS 6 BP 1768 EP 1779 DI 10.3758/s13414-011-0136-4 PG 12 WC Psychology; Psychology, Experimental SC Psychology GA 805DG UT WOS:000293706000011 PM 21533921 ER PT J AU Luzum, B Capitaine, N Fienga, A Folkner, W Fukushima, T Hilton, J Hohenkerk, C Krasinsky, G Petit, G Pitjeva, E Soffel, M Wallace, P AF Luzum, Brian Capitaine, Nicole Fienga, Agnes Folkner, William Fukushima, Toshio Hilton, James Hohenkerk, Catherine Krasinsky, George Petit, Gerard Pitjeva, Elena Soffel, Michael Wallace, Patrick TI The IAU 2009 system of astronomical constants: the report of the IAU working group on numerical standards for Fundamental Astronomy SO CELESTIAL MECHANICS & DYNAMICAL ASTRONOMY LA English DT Article DE Numerical standards; Fundamental Astronomy; Fundamental constants ID CODATA RECOMMENDED VALUES; GRAVITY-FIELD; PHYSICAL CONSTANTS; TRACKING DATA; PRECESSION; EPHEMERIS; MASSES; EARTH; ORIENTATION; SATELLITES AB In the 2006-2009 triennium, the International Astronomical Union (IAU) Working Group on Numerical Standards for Fundamental Astronomy determined a list of Current Best Estimates (CBEs). The IAU 2009 Resolution B2 adopted these CBEs as the IAU (2009) System of Astronomical Constants. Additional work continues to define the process of updating the CBEs and creating a standard electronic document. C1 [Luzum, Brian; Hilton, James] USN Observ, Washington, DC 20392 USA. [Capitaine, Nicole] UPMC, CNRS, SYRTE, Observ Paris, Paris, France. [Fienga, Agnes] Univ Franche Comte, Inst UTINAM, CNRS, UMR 6123, F-25030 Besancon, France. [Folkner, William] CALTECH, Jet Prop Lab, Pasadena, CA USA. [Fukushima, Toshio] Natl Astron Observ, Tokyo 181, Japan. [Hohenkerk, Catherine] HM Naut Almanac Off, Taunton, Somerset, England. [Krasinsky, George; Pitjeva, Elena] RAS, Inst Appl Astron, St Petersburg, Russia. [Petit, Gerard] Bur Int Poids & Mesures, Sevres, France. [Soffel, Michael] Tech Univ Dresden, Dresden, Germany. [Wallace, Patrick] Rutherford Appleton Lab, Chilton, England. RP Luzum, B (reprint author), USN Observ, Washington, DC 20392 USA. EM brian.luzum@usno.navy.mil NR 35 TC 27 Z9 29 U1 0 U2 5 PU SPRINGER PI DORDRECHT PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS SN 0923-2958 J9 CELEST MECH DYN ASTR JI Celest. Mech. Dyn. Astron. PD AUG PY 2011 VL 110 IS 4 BP 293 EP 304 DI 10.1007/s10569-011-9352-4 PG 12 WC Astronomy & Astrophysics; Mathematics, Interdisciplinary Applications SC Astronomy & Astrophysics; Mathematics GA 801TX UT WOS:000293464600002 ER PT J AU Swanekamp, SB Apruzese, JP Commisso, RJ Mosher, D Schumer, JW AF Swanekamp, S. B. Apruzese, J. P. Commisso, R. J. Mosher, D. Schumer, J. W. TI An Analysis of Intense Pulsed Active Detection (IPAD) for the Detection of Special Nuclear Materials SO IEEE TRANSACTIONS ON NUCLEAR SCIENCE LA English DT Article DE Bremsstrahlung; gamma-rays; homeland security; neutrons; radiation dosage AB We propose and analyze computationally the Intense Pulsed Active Detection (IPAD) of fissile materials. This approach employs bremsstrahlung photons from a single intense 100-ns interrogating pulse produced by a pulsed-power generator. The IPAD system requires only 3 s to detect delayed neutrons. In contrast, a multiple-pulse-train LINAC system requires several minutes. Because of the much smaller interrogation time, the IPAD system offers a much greater contrast between the induced signal and the cosmic-ray neutron background. For a similar signal-to-noise ratio as the LINAC system the IPAD offers a greatly reduced tissue dose. For a similar dose the IPAD offers a greater signal-to-noise with a much smaller false alarm rate. Our detailed numerical analysis employs the ITS and MCNPX codes, from which we have calculated critical quantities such as the number of delayed neutrons per unit dose and the number of prompt fission neutrons that can be distinguished from photoneutrons created in benign materials such as would arise from (207)Pb. Some fundamental scaling relations have also been developed from our computations. For bremsstrahlung endpoint energies (E(end)) well below the giant dipole resonance, the neutrons per dose increase as the 9th power of the E(end) which transitions to the 2nd power as E(end) increases beyond the giant dipole resonance. The tissue dose scales as the 2nd power of E(end) throughout the range. Therefore, for any applications where the total dose is limited, no additional photo-fission neutrons are produced at high bremsstrahlung endpoints. C1 [Swanekamp, S. B.; Commisso, R. J.; Schumer, J. W.] USN, Res Lab, Div Plasma Phys, Washington, DC 20375 USA. [Apruzese, J. P.; Mosher, D.] L 3 Commun, Washington, DC USA. RP Swanekamp, SB (reprint author), USN, Res Lab, Div Plasma Phys, Washington, DC 20375 USA. EM Steve.Swanekamp@nrl.navy.mil; John.Apruzese@nrl.navy.mil; Robert.Commisso@nrl.navy.mil; David.Mosher@nrl.navy.mil; Joseph.Schumer@nrl.navy.mil RI Schumer, Joseph/D-7591-2013 NR 12 TC 9 Z9 9 U1 0 U2 9 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0018-9499 J9 IEEE T NUCL SCI JI IEEE Trans. Nucl. Sci. PD AUG PY 2011 VL 58 IS 4 BP 2047 EP 2054 DI 10.1109/TNS.2011.2150242 PN 2 PG 8 WC Engineering, Electrical & Electronic; Nuclear Science & Technology SC Engineering; Nuclear Science & Technology GA 808KS UT WOS:000293977200023 ER PT J AU El Sherif, M Esona, MD Wang, YH Gentsch, JR Jiang, BM Glass, RI Abou Baker, S Klena, JD AF El Sherif, May Esona, Mathew D. Wang, Yuhuan Gentsch, Jon R. Jiang, Baoming Glass, Roger I. Abou Baker, Shermine Klena, John D. TI Detection of the first G6P[14] human rotavirus strain from a child with diarrhea in Egypt SO INFECTION GENETICS AND EVOLUTION LA English DT Article DE Group A rotavirus; Phylogenetic analysis; Viral reassortment; Egypt ID GROUP-A ROTAVIRUS; POLYMERASE-CHAIN-REACTION; SEROTYPE G6; PHYLOGENETIC ANALYSIS; MOLECULAR EPIDEMIOLOGY; BOVINE ROTAVIRUSES; VP7; G8; IDENTIFICATION; INDIA AB We report the first detection of a G6P[14] rotavirus strain in Egypt from the stool of a child participating in a hospital-based diarrhea surveillance study conducted throughout the year 2004. Rotavirus infection was initially detected using a rotavirus group A VP6 enzyme immunoassay; the P (VP4) and G (VP7) genotypes of the strain were identified by RT-PCR. We sequenced the VP7 gene and the VP8* portion of the VP4 gene and the strain displayed the strongest identity to the VP7 [>94% nucleotides (nt), >97% amino acids (aa)] and VP4 (>93% nt. >98% aa) sequences of PA169, a novel G6P[14] strain first isolated from a child in Italy during the winter of 1987. Additional sequencing and analysis of the other remaining structural (VP1-VP3. VP6) and non-structural (NSP1-NSP5) proteins support this animal-to-human reassortment theory. According to the full genome classification system, the G6P[14] strain (EGY3399) was assigned to G6-P[14]-I2-R2-C2-M2-A11-N2-T6-E2-H3 genotypes. The greatest similarity of EGY3399 NSP4 and NSP5 gene sequences were to those of ovine and simian origin, respectively. Coupled with other observations, our results suggest G6P[14] isolates rarely cause severe diarrhea in Egyptian children, and support other studies that indicate animal rotavirus contribute to the genetic diversity of rotavirus detected from humans through interspecies transmission and single or multiple segments reassortment. Published by Elsevier B.V. C1 [El Sherif, May; Klena, John D.] USN, Med Res Unit 3, Cairo, Egypt. [Esona, Mathew D.; Wang, Yuhuan; Gentsch, Jon R.; Jiang, Baoming; Glass, Roger I.] US Ctr Dis Control & Prevent, Atlanta, GA USA. [Abou Baker, Shermine] Minist Hlth & Populat, Gen Directorate Communicable Dis Control, Cairo, Egypt. RP El Sherif, M (reprint author), NAMRU 3,PSC 452 Box 5000, FPO, AE 09835 USA. EM may.elsherif.eg@med.navy.mil RI Valle, Ruben/A-7512-2013 FU Association of Public Health Laboratories; Centers for Disease Control and Prevention (CCID/CDC); Armed Forces Health Surveillance Center/Div. of Global Emerging Infections System Operations [847705.82000.25GB.E0018 GEIS]; Program for Appropriate Technology in Health (PATH) [NCRADA-NAMRU-3-06-2365] FX This study was conducted during a fellowship sponsored by Association of Public Health Laboratories and the Centers for Disease Control and Prevention (CCID/CDC). We thank all our colleagues at the Viral Gastroenteritis Section, Gastroenteritis and Respiratory Viruses Laboratory Branch, Division of Viral Diseases, CCID/CDC for their assistance in making this work possible. We would like to acknowledge Dr. Adel Mansour and Dr. Ibrahim Adib for their supervision of the Abu Homos hospital-based diarrhea surveillance study. We also thank Dr. George Armah, Noguchi Medical Research Institute, Accra, Ghana for his thoughtful review and critique of the manuscript.; Armed Forces Health Surveillance Center/Div. of Global Emerging Infections System Operations (Work Unit no. 847705.82000.25GB.E0018 GEIS) and Program for Appropriate Technology in Health (PATH; Work Unit no. NCRADA-NAMRU-3-06-2365). NR 51 TC 23 Z9 23 U1 0 U2 0 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 1567-1348 J9 INFECT GENET EVOL JI Infect. Genet. Evol. PD AUG PY 2011 VL 11 IS 6 BP 1436 EP 1442 DI 10.1016/j.meegid.2011.05.012 PG 7 WC Infectious Diseases SC Infectious Diseases GA 806JV UT WOS:000293804600035 PM 21640199 ER PT J AU Zheng, YX Shinoda, T Lin, JL Kiladis, GN AF Zheng, Yangxing Shinoda, Toshiaki Lin, Jia-Lin Kiladis, George N. TI Sea Surface Temperature Biases under the Stratus Cloud Deck in the Southeast Pacific Ocean in 19 IPCC AR4 Coupled General Circulation Models SO JOURNAL OF CLIMATE LA English DT Article ID DATA ASSIMILATION ANALYSIS; TROPICAL PACIFIC; SEASONAL CYCLE; GLOBAL OCEANS; HEAT FLUXES; REANALYSIS; VARIABILITY; CLIMATE; PARAMETERIZATION; ATTRIBUTION AB This study examines systematic biases in sea surface temperature (SST) under the stratus cloud deck in the southeast Pacific Ocean and upper-ocean processes relevant to the SST biases in 19 coupled general circulation models (CGCMs) participating in the Intergovernmental Panel on Climate Change (IPCC) Fourth Assessment Report (AR4). The 20 years of simulations from each model are analyzed. Pronounced warm SST biases in a large portion of the southeast Pacific stratus region are found in all models. Processes that could contribute to the SST biases are examined in detail based on the computation of major terms in the upper-ocean heat budget. Negative biases in net surface heat fluxes are evident in most of the models, suggesting that the cause of the warm SST biases in models is not explained by errors in net surface heat fluxes. Biases in heat transport by Ekman currents largely contribute to the warm SST biases both near the coast and the open ocean. In the coastal area, southwestward Ekman currents and upwelling in most models are much weaker than observed owing to weaker alongshore winds, resulting in insufficient advection of cold water from the coast. In the open ocean, warm advection due to Ekman currents is overestimated in models because of the larger meridional temperature gradient, the smaller zonal temperature gradient, and overly weaker Ekman currents. C1 [Zheng, Yangxing] Univ Colorado, Cooperat Inst Res Environm Sci, Boulder, CO 80309 USA. [Shinoda, Toshiaki] USN, Res Lab, Stennis Space Ctr, MS 39529 USA. [Lin, Jia-Lin] Ohio State Univ, Dept Geog, Columbus, OH 43210 USA. [Kiladis, George N.] NOAA, Earth Syst Res Lab, Div Phys Sci, Boulder, CO USA. RP Zheng, YX (reprint author), Florida State Univ, Ctr Ocean Atmospher Predict Studies, 2035 E Paul Dirac Dr,Johnson Bldg, Tallahassee, FL 32306 USA. EM yzheng@fsu.edu RI Zheng, Yangxing/B-7965-2013; Shinoda, Toshiaki/J-3745-2016 OI Zheng, Yangxing/0000-0003-2039-1494; Shinoda, Toshiaki/0000-0003-1416-2206 FU NSF [OCE-0453046, AGS-0966844, ATM-0745897, ATM-0745872]; NOAA CPO [GC-10-400]; Office of Naval Research (ONR) [601153N]; National Aeronautics and Space Administration (NASA) FX We are greatly indebted to all those who contributed to the observations and global datasets used in this study. We thank Simon de Szoeke, Editor Robert Wood, and two anonymous reviewers for their helpful comments. Computational facilities have been provided by the National Oceanic and Atmospheric Administration (NOAA). Yangxing Zheng is supported by NSF Grant OCE-0453046. Toshiaki Shinoda is supported by NOAA CPO Grant GC-10-400 under the Modeling, Analysis, and Prediction (MAP) Program; the NSF Grants OCE-0453046, AGS-0966844, and ATM-0745897; and 6.1 projects sponsored by the Office of Naval Research (ONR) under Program Element 601153N. Jia-Lin Lin is supported by the National Aeronautics and Space Administration (NASA) under the MAP program and by NSF Grant ATM-0745872. NR 48 TC 35 Z9 35 U1 0 U2 6 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 USA SN 0894-8755 EI 1520-0442 J9 J CLIMATE JI J. Clim. PD AUG PY 2011 VL 24 IS 15 BP 4139 EP 4164 DI 10.1175/2011JCLI4172.1 PG 26 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA 806QE UT WOS:000293823900023 ER PT J AU La Follett, JR Williams, KL Marston, PL AF La Follett, Jon R. Williams, Kevin L. Marston, Philip L. TI Boundary effects on backscattering by a solid aluminum cylinder: Experiment and finite element model comparisons SO JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA LA English DT Article ID ACOUSTIC SCATTERING; RAYLEIGH-WAVES; OBJECTS; ENHANCEMENTS; WATER AB Backscattering of sound by a solid aluminum cylinder was measured in the free field and with the cylinder near a flat surface. The target was suspended just below the surface of a water tank to simulate some aspects of backscattering when resting on the seabed. Measurements were compared with predictions made by an approximate hybrid approach based on multiple two-dimensional finite element calculations and the use of images. Many of the spectral features present in the tank data were present in the model. Comparing numerical model predictions with experimental data serves to build credibility for the modeling approach and can assist in developing insight into the underlying physical processes. [DOI: 10.1121/1.3613806] C1 [La Follett, Jon R.] USN, Ctr Surface Warfare, Panama City Div, Panama City, FL 32407 USA. [Williams, Kevin L.] Univ Washington, Coll Ocean & Fishery Sci, Appl Phys Lab, Seattle, WA 98105 USA. [Marston, Philip L.] Washington State Univ, Dept Phys & Astron, Pullman, WA 99164 USA. RP La Follett, JR (reprint author), USN, Ctr Surface Warfare, Panama City Div, Panama City, FL 32407 USA. EM jon.lafollet@navy.mil RI williams, kevin/H-2224-2011 FU Office of Naval Research FX This research was supported by the Office of Naval Research. Assistance in the development and testing of the experimental facility at Washington State University was provided by C. Dudley, K. Baik, and A. L. Espana. NR 12 TC 6 Z9 6 U1 1 U2 7 PU ACOUSTICAL SOC AMER AMER INST PHYSICS PI MELVILLE PA STE 1 NO 1, 2 HUNTINGTON QUADRANGLE, MELVILLE, NY 11747-4502 USA SN 0001-4966 J9 J ACOUST SOC AM JI J. Acoust. Soc. Am. PD AUG PY 2011 VL 130 IS 2 BP 669 EP 672 DI 10.1121/1.3613806 PG 4 WC Acoustics; Audiology & Speech-Language Pathology SC Acoustics; Audiology & Speech-Language Pathology GA 807BK UT WOS:000293866800012 PM 21877778 ER PT J AU Finneran, JJ Mulsow, J Schlundt, CE Houser, DS AF Finneran, James J. Mulsow, Jason Schlundt, Carolyn E. Houser, Dorian S. TI Dolphin and sea lion auditory evoked potentials in response to single and multiple swept amplitude tones SO JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA LA English DT Article ID STEADY-STATE RESPONSES; TRUNCATUS HEARING THRESHOLDS; TURSIOPS-TRUNCATUS; LAGENORHYNCHUS-ALBIROSTRIS; TEMPORAL RESOLUTION; LATERAL SUPPRESSION; FREQUENCY; MODULATION; SYSTEM; SENSITIVITY AB Measurement of the auditory steady-state response (ASSR) is increasingly used to assess marine mammal hearing. These tests normally entail measuring the ASSR to a sequence of sinusoidally amplitude modulated tones, so that the ASSR amplitude function can be defined and the auditory threshold estimated. In this study, an alternative method was employed, where the ASSR was elicited by an amplitude modulated stimulus whose sound pressure level was slowly varied, or "swept," over a range of levels believed to bracket the threshold. The ASSR amplitude function was obtained by analyzing the resulting grand average evoked potential using a short-time Fourier transform. The suitability of this technique for hearing assessment of bottlenose dolphins and California sea lions was evaluated by comparing ASSR amplitude functions and thresholds obtained with swept amplitude and discrete, constant amplitude stimuli. When factors such as the number of simultaneous tones, the number of averages, and the frequency analysis window length were taken into account, the performance and time required for the swept-amplitude and discrete stimulus techniques were similar. The decision to use one technique over another depends on the relative importance of obtaining suprathreshold information versus the lowest possible thresholds. (C) 2011 Acoustical Society of America. [DOI: 10.1121/1.3608117] C1 [Finneran, James J.; Mulsow, Jason] USN, Marine Mammal Program, Space & Naval Warfare Syst Ctr, San Diego, CA 92152 USA. [Schlundt, Carolyn E.] ITT Corp, San Diego, CA 92110 USA. [Houser, Dorian S.] Natl Marine Mammal Fdn, San Diego, CA 92106 USA. RP Finneran, JJ (reprint author), USN, Marine Mammal Program, Space & Naval Warfare Syst Ctr, Code 71510,53560 Hull St, San Diego, CA 92152 USA. EM james.finneran@navy.mil OI Houser, Dorian/0000-0002-0960-8528 FU U.S. Office of Naval Research; Marine Mammal Science and Technology Program; SSC Pacific In-house Laboratory FX Keri Wickersham, Amber Arnold, Lisa Gibler, Linda Green, Megan Tormey, Hitomi Aihara, Jim Powell, and Randall Dear provided animal training and logistic support. Dr. Eric Jensen, Dr. Shawn Johnson, Dr. Betsy Lutmerding, Dr. Forrest Gomez, and Dr. Carolina Ruiz provided veterinary care during the sea lion anesthesia. Financial support was provided by the U.S. Office of Naval Research, Marine Mammal Science and Technology Program and the SSC Pacific In-house Laboratory Independent Research Program. This study followed a protocol approved by the Institutional Animal Care and Use Committee at SSC Pacific. NR 53 TC 6 Z9 6 U1 1 U2 6 PU ACOUSTICAL SOC AMER AMER INST PHYSICS PI MELVILLE PA STE 1 NO 1, 2 HUNTINGTON QUADRANGLE, MELVILLE, NY 11747-4502 USA SN 0001-4966 J9 J ACOUST SOC AM JI J. Acoust. Soc. Am. PD AUG PY 2011 VL 130 IS 2 BP 1038 EP 1048 DI 10.1121/1.3608117 PG 11 WC Acoustics; Audiology & Speech-Language Pathology SC Acoustics; Audiology & Speech-Language Pathology GA 807BK UT WOS:000293866800050 PM 21877816 ER PT J AU Eckermann, SD AF Eckermann, Stephen D. TI Explicitly Stochastic Parameterization of Nonorographic Gravity Wave Drag SO JOURNAL OF THE ATMOSPHERIC SCIENCES LA English DT Article ID ENSEMBLE PREDICTION SYSTEM; GENERAL-CIRCULATION MODEL; MIDDLE-ATMOSPHERE; SPECTRAL PARAMETERIZATION; PHYSICAL PARAMETERIZATIONS; CLIMATE PREDICTION; LOWER STRATOSPHERE; MOMENTUM FLUXES; ECMWF MODEL; MEAN-FLOW AB A straightforward methodology is presented for converting the deterministic multiwave parameterizations of nonorographic gravity wave drag, currently used in general circulation models (GCMs), to stochastic analogs that use fewer waves (in the example herein, a single wave) within each grid box. Deterministic discretizations of source-level momentum flux spectra using a fixed spectrum of many waves with predefined phase speeds are replaced by sampling these source spectra stochastically using waves with randomly assigned phase speeds. Using simple conversion formulas, it is shown that time-mean wave-induced drag, diffusion, and heating-rate profiles identical to those from the deterministic scheme are produced by the stochastic analog. Furthermore, in these examples the need for bulk intermittency factors of small value is largely obviated through the explicit incorporation of stochastic intermittency into the scheme. When implemented in a GCM, the single-wave stochastic analog of an existing deterministic scheme reproduces almost identical time-mean middle-atmosphere climate and drag as its deterministic antecedent but with an order of magnitude reduction in computational expense. The stochastically parameterized drag is also accompanied by inherent variability about the time-mean profile that forces the smallest space-time scales of the GCM. Studies of mean GCM kinetic energy spectra show that this additional stochastic forcing does not lead to excessive increases in dynamical variability at these smallest GCM scales. The results show that the expensive deterministic schemes currently used in GCMs are easily modified and replaced by cheap stochastic analogs without any obvious deleterious impacts on GCM climate or variability, while offering potential advantages of computational savings, reduction of systematic climate biases, and greater and more realistic ensemble spread. C1 USN, Div Space Sci, Res Lab, Washington, DC 20375 USA. RP Eckermann, SD (reprint author), USN, Div Space Sci, Res Lab, Code 7646,4555 Overlook Ave SW, Washington, DC 20375 USA. EM stephen.eckermann@nrl.navy.mil FU Office of Naval Research through the NRL; NASA [NNTG06HM19I] FX This research was supported by the Office of Naval Research through the NRL 6.1 work unit "Subgrid-scale Dynamics of Middle and Upper Atmospheres" and by NASA's Global Modeling and Analysis Program, Contract NNTG06HM19I. Discussions with Julio Bacmeister, In-Sun Song, and Fabrizio Sassi on these topics are gratefully acknowledged. NR 67 TC 22 Z9 24 U1 2 U2 12 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 USA SN 0022-4928 J9 J ATMOS SCI JI J. Atmos. Sci. PD AUG PY 2011 VL 68 IS 8 BP 1749 EP 1765 DI 10.1175/2011JAS3684.1 PG 17 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA 803ZN UT WOS:000293622300012 ER PT J AU Erba, P Adini, A Demcheva, M Valeri, CR Orgill, DP AF Erba, Paolo Adini, Avner Demcheva, Marina Valeri, C. Robert Orgill, Dennis P. TI Poly-N-Acetyl Glucosamine Fibers Are Synergistic With Vacuum-Assisted Closure in Augmenting the Healing Response of Diabetic Mice SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Article DE Poly-N-acetyl glucosamine fibers; VAC; Wound healing; Diabetic mice ID CELL-PROLIFERATION; TISSUE; BANDAGE; CULTURE; FORCES; LOAD AB Background: Vacuum-assisted closure (VAC) has become the preferred modality to treat many complex wounds but could be further improved by methods that minimize bleeding and facilitate wound epithelialization. Short fiber poly-N-acetyl glucosamine nanofibers (sNAG) are effective hemostatic agents that activate platelets and facilitate wound epithelialization. We hypothesized that sNAG used in combination with the VAC device could be synergistic in promoting wound healing while minimizing the risk of bleeding. Methods: Membranes consisting entirely of sNAG nanofibers were applied immediately to dorsal excisional wounds of db/db mice followed by application of the VAC device. Wound healing kinetics, angiogenesis, and wound-related growth factor expression were measured. Results: The application of sNAG membranes to wounds 24 hours before application of the VAC device was associated with a significant activation of wounds (expression of PDGF, TGF beta, EGF), superior granulation tissue formation rich in Collagen I as well as superior wound epithelialization (8.6% +/- 0.3% vs. 1.8% +/- 1.1% of initial wound size) and wound contraction. Conclusions: The application of sNAG fiber-containing membranes before the application of the polyurethane foam interface of VAC devices leads to superior healing in db/db mice and represents a promising wound healing adjunct that can also reduce the risk of bleeding complications. C1 [Erba, Paolo] Univ Basel Hosp, Dept Plast Reconstruct & Aesthet Surg, Div Plast & Reconstruct Surg, CH-4031 Basel, Switzerland. [Erba, Paolo] Univ Lausanne Hosp, Div Plast & Reconstruct Surg, CH-4031 Basel, Switzerland. [Adini, Avner] Harvard Univ, Childrens Hosp, Sch Med, Vasc Biol Program,Dept Surg, Boston, MA 02115 USA. [Orgill, Dennis P.] Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Plast Surg, Boston, MA 02115 USA. [Demcheva, Marina] Marine Polymer Technol, Danvers, MA USA. [Valeri, C. Robert] USN, Blood Res Lab Inc, Boston, MA USA. RP Erba, P (reprint author), Univ Basel Hosp, Dept Plast Reconstruct & Aesthet Surg, Div Plast & Reconstruct Surg, CH-4031 Basel, Switzerland. EM erbapaolo@hotmail.com OI Orgill, Dennis/0000-0002-8279-7310 FU Marine Polymer Technologies, Inc., Danvers, MA; Marine Polymers, Inc.; Kinetic Concepts Inc. (KCI) FX The Tissue Engineering and Wound Healing Laboratory at Brigham and Women's Hospital acknowledges Marine Polymer Technologies, Inc., Danvers, MA, for their material and financial support of this project.; Supported, in part, by a research contract from Marine Polymers, Inc. to Brigham and Women's Hospital. During the time of the experiment, Dr. Orgill was a principal investigator for a research study funded by Kinetic Concepts Inc. (KCI) to Brigham and Women's Hospital. NR 23 TC 6 Z9 6 U1 0 U2 0 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0022-5282 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD AUG PY 2011 VL 71 SU 1 BP S187 EP S193 DI 10.1097/TA.0b013e318225583c PG 7 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 806WZ UT WOS:000293849000007 PM 21814117 ER PT J AU Fischer, TH Hays, WE Valeri, CR AF Fischer, Thomas H. Hays, William E. Valeri, C. Robert TI Poly-N-Acetyl Glucosamine Fibers Accelerate Hemostasis in Patients Treated With Antiplatelet Drugs SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Article DE Hemostasis; Poly-N-acetyl glucosamine nanofibers; Thromboelastogram; Acetyl salicylic acid; Corn trypsin inhibitor ID SICKLE-CELL-DISEASE; RED-BLOOD-CELLS; MEDIATED HEMOSTASIS; PLATELETS; MECHANISMS; HEMORRHAGE; GENERATION; FIBRINOGEN; SURFACES; ADHESION AB Background: Nanofibers consisting of poly-N-acetyl glucosamine (pGlcNAc), as the functional component of products for surface hemostasis, have been shown to activate platelets and thereby the clotting mechanism. The nanofiber-activated platelets provide a catalytic surface for acceleration of the intrinsic coagulation cascade, thrombin generation, and fibrin polymerization. Methods: Thromboelastographic analysis was undertaken to study the role of the pGlcNAc nanofibers in platelet activation and acceleration of fibrin polymerization. Thromboelastographic studies were performed without added activators of coagulation. Results: The pGlcNAc nanofibers were found to accelerate fibrin polymerization in whole blood and platelet-rich plasma. Treatment with eptifibatide (an inhibitor of the platelet GPIIbIIIa receptor) and corn trypsin inhibitor inhibited clotting of whole blood and platelet-rich plasma. The inhibition was reversed by treatment with pGlcNAc nanofibers. Inhibition was not observed after treatment with aspirin alone, MRS2359 (platelet ADP receptor inhibitor), or by a combination of aspirin and MRS2359. The pGlcNAc nanofibers accelerate clotting in normal blood treated with aspirin and MRS2359. Clopidogrel (Plavix) and aspirin did not affect the kinetics of pGlcNAc-mediated fibrin polymerization in blood from patients treated with antiplatelet drugs compared with nontreated blood. Conclusions: These results provide evidence that pGlcNAc nanofibers activate platelets and accelerate the clotting of blood, and on how best to achieve surface hemostasis when patients are coagulopathic because of shock and/or to treatment with antiplatelet drugs. C1 [Fischer, Thomas H.; Hays, William E.] Univ N Carolina, Francis Owen Blood Res Lab, Dept Pathol & Lab Med, Chapel Hill, NC 27516 USA. [Valeri, C. Robert] USN, Blood Res Lab, Boston, MA USA. RP Fischer, TH (reprint author), Univ N Carolina, Francis Owen Blood Res Lab, Dept Pathol & Lab Med, 125 Univ Lake Dr,CB 3114, Chapel Hill, NC 27516 USA. EM tfischer@med.inc.edu NR 32 TC 3 Z9 4 U1 5 U2 11 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0022-5282 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD AUG PY 2011 VL 71 SU 1 BP S176 EP S182 DI 10.1097/TA.0b013e318225570d PG 7 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 806WZ UT WOS:000293849000005 PM 21814115 ER PT J AU Scherer, SS Pietramaggiori, G Matthews, JC Gennaoui, A Demcheva, M Fischer, TH Valeri, CR Orgill, DP AF Scherer, Saja S. Pietramaggiori, Giorgio Matthews, Jasmine C. Gennaoui, Anthony Demcheva, Marina Fischer, Thomas H. Valeri, C. Robert Orgill, Dennis P. TI Poly-N-Acetyl Glucosamine Fibers Induce Angiogenesis in ADP Inhibitor-Treated Diabetic Mice SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Article DE Angiogenesis; Diabetic wounds; Poly-N-acetyl glucosamine; Clopidogrel ID PLATELET-RICH PLASMA; FOOT ULCERS; CLOPIDOGREL; ACTIVATION AB Background: It has been previously demonstrated that short-fiber poly-N-acetyl-glucosamine (sNAG) nanofibers specifically interact with platelets, are hemostatic, and stimulate diabetic wound healing by activating angiogenesis, cell proliferation, and reepithelialization. Platelets play a significant physiologic role in wound healing. The influence of altered platelet function by treatment with the ADP inhibitor Clopidogrel (CL) on wound healing and the ability of sNAG to repair wounds in diabetic mice treated with CL were studied. Methods: Dorsal 1 cm2 skin wounds were excised on genetically diabetic 8-week to 12-week-old, Lep/r-db/db male mice, and wound healing kinetics were determined. Microscopic analysis was performed for angiogenesis (PECAM-1) and cell proliferation (Ki67). Mice were either treated with CL (P2Y12 ADP receptor antagonist, CL) or saline solution (NT). CL wounds were also treated with either a single application of topical sNAG (CL-sNAG) or were left untreated (CL-NT). Results: CL treatment did not alter wound healing kinetics, while sNAG induced faster wound closure in CL-treated mice compared with controls. CL treatment of diabetic mice caused an augmentation of cell proliferation and reduced angiogenesis compared with nontreated wounds. However, sNAG reversed the effects of CL on angiogenesis and partially reversed the effect on cell proliferation in the wound beds. The sNAG-treated wounds in CL-treated mice showed higher levels of cell proliferation and not did inhibit angiogenesis. Conclusions: CL treatment of diabetic mice decreased angiogenesis and increased cell proliferation in wounds but did not influence macroscopic wound healing kinetics. sNAG treatment did not inhibit angiogenesis in CL-treated mice and induced faster wound closure; sNAG technology is a promising strategy to facilitate the healing of complex bleeding wounds in CL-treated diabetic patients. C1 [Matthews, Jasmine C.; Orgill, Dennis P.] Harvard Univ, Sch Med, Brigham & Womens Hosp, Div Plast Surg, Boston, MA 02115 USA. [Scherer, Saja S.; Pietramaggiori, Giorgio] Univ Lausanne Hosp, Dept Plast Surg, Lausanne, Switzerland. [Demcheva, Marina] Marine Polymer Technol, Danvers, MA USA. [Fischer, Thomas H.] Univ N Carolina, Dept Pathol & Lab Med, Chapel Hill, NC USA. [Gennaoui, Anthony; Valeri, C. Robert] USN, Blood Res Lab Inc, Boston, MA USA. RP Orgill, DP (reprint author), Harvard Univ, Sch Med, Brigham & Womens Hosp, Div Plast Surg, 75 Francis St, Boston, MA 02115 USA. EM dorgill@partners.org OI Orgill, Dennis/0000-0002-8279-7310 FU Marine Polymer Technologies, Inc., Danvers, MA, FX The Tissue Engineering and Wound Healing Laboratory at Brigham and Women's Hospital acknowledge Marine Polymer Technologies, Inc., Danvers, MA, for their material and financial support of this project. NR 18 TC 6 Z9 6 U1 0 U2 5 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0022-5282 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD AUG PY 2011 VL 71 SU 1 BP S183 EP S186 DI 10.1097/TA.0b013e318225585b PG 4 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 806WZ UT WOS:000293849000006 PM 21814116 ER PT J AU Valeri, CR Vournakis, JN AF Valeri, C. Robert Vournakis, John N. TI mRDH Bandage for Surgery and Trauma: Data Summary and Comparative Review SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Review DE Hemorrhage; Hemostasis; mRDH; Trauma; Surgery; pGlcNAc ID N-ACETYL GLUCOSAMINE; EXTREMITY ARTERIAL HEMORRHAGE; HEMOSTATIC AGENTS; MEDIATED HEMOSTASIS; CARDIAC-SURGERY; DOUBLE-BLIND; SWINE MODEL; BLOOD-LOSS; COAGULOPATHY; TRANSFUSION AB Background: Bleeding often poses significant life-threatening situations to surgeons. After trauma, a one-third of civilian casualties and one-half of combat casualties die as a result of exsanguination. Recent advances have provided promising new hemostatic dressings that are applied directly to severely bleeding wounds in the pre-hospital period. Methods: The modified Rapid Deployment Hemostat (mRDH) trauma/surgery bandage, containing fully acetylated, diatom-derived, poly-N-acetylglucosamine fibers, has a unique multifactorial hemostatic action that incorporates vasoconstriction, erythrocyte agglutination, and platelet and RBC activation. Results: Animal studies have shown that the mRDH bandage quickly and completely stops both venous and arterial bleeding, even in the presence of a coagulopathy. A prospective study in humans is in accord with these findings. Conclusion: The mRDH trauma/surgery bandage was able to increase survival of patients after high-grade liver trauma with an associated coagulopathy. Additional clinical studies support this result. C1 [Vournakis, John N.] Marine Polymer Technol Inc, Burlington, MA 01803 USA. [Valeri, C. Robert] USN, Blood Res Lab Inc, Boston, MA USA. RP Vournakis, JN (reprint author), Marine Polymer Technol Inc, 24 New England Execut Pk,Suite 210, Burlington, MA 01803 USA. EM johnv@webmpt.com NR 51 TC 4 Z9 4 U1 1 U2 4 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0022-5282 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD AUG PY 2011 VL 71 SU 1 BP S162 EP S166 DI 10.1097/TA.0b013e31822555e9 PG 5 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 806WZ UT WOS:000293849000002 PM 21814112 ER PT J AU Sharkey, JM Rennix, CP AF Sharkey, Jessica M. Rennix, Christopher P. TI Assessment of Changes in Mental Health Conditions Among Sailors and Marines During Postdeployment Phase SO MILITARY MEDICINE LA English DT Article; Proceedings Paper CT 12th Annual Force Health Protection Conference CY AUG, 2009 CL Albuquerque, NM ID POSTTRAUMATIC-STRESS-DISORDER; WAR VETERANS; COMBAT VETERANS; IRAQ; AFGHANISTAN; MILITARY; CARE; COMPONENT AB Previous research regarding the mental health ramifications of military deployments focused on the U.S. Army population. As part of its deployment health surveillance mission, Navy and Marine Corps Public Health Center conducted a study of the Department of Navy population to identify reported mental health effects associated with Operation Iraqi Freedom, describe mental health care utilization by returning service members previously deployed in support of Operation Iraqi Freedom, and examine the relationships between self-identified risks and provider referral practices. Despite a considerable number of self-reported mental health concerns, referral for mental health consultations and health care utilization were rare. The psychological well-being of service members is essential to the military's optimum functionality and operational readiness; therefore, continued research in this area has significant bearing on future force health protection efforts. Additionally, this study highlights the need for further research on deployment-related mental health concerns. C1 [Rennix, Christopher P.] USN, Med Ctr Portsmouth, Navy & Marine Corps Publ Hlth Ctr, Portsmouth, VA 23708 USA. RP Sharkey, JM (reprint author), 200 Cedar St, Delanco, NJ 08075 USA. NR 16 TC 3 Z9 3 U1 0 U2 2 PU ASSOC MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA SN 0026-4075 J9 MIL MED JI Milit. Med. PD AUG PY 2011 VL 176 IS 8 BP 915 EP 921 PG 7 WC Medicine, General & Internal SC General & Internal Medicine GA 804TB UT WOS:000293675800012 PM 21882782 ER PT J AU Smith, JD Amundson, DE Harrell, T AF Smith, Jordan D. Amundson, Dennis E. Harrell, Travis TI Prevalence of Short Partial Thromboplastin Times in a Military Treatment Facility SO MILITARY MEDICINE LA English DT Article ID VENOUS THROMBOEMBOLISM; PLASMA-LEVELS; INCREASED RISK; FACTOR-VIII; THROMBOSIS; VALUES AB Background: It was recently noted that a shortened activated partial thromboplastin time (aPTT) is associated with increased venous thromboembolic events. The prevalence of aPTT shortening remains unknown. Methods: We conducted a retrospective analysis of aPTT results over a 2-month period. These results were not associated with patient clinical information. Results: We obtained 3,376 aPTT samples, which were analyzed in groups: < 25.0, 25.0-35.0, and > 35.0 seconds (two standard deviations from our laboratory's normal values). Eighty-six samples had aPTT < 25 (8.5%), 2,026 samples between 25.0-35.0 (60.0%), and 1,064 samples > 35.0 (31.5%). Using chi-square goodness-of-fit, we found a clinically significant greater-than-expected prevalence of low aPTT levels (p < 0.001). Conclusions: Although elevated aPTT samples could be explained by anticoagulation therapy, the reason for our findings of an increased number of low-aPTT studies remains unexplained. Further studies are required to investigate the clinical correlation of low aPTT levels and the incidence of venous thromboembolic events (VTEs) in our population. C1 [Smith, Jordan D.] USN, San Diego Med Ctr, Dept Pulm, San Diego, CA 92134 USA. USN, San Diego Med Ctr, Dept Crit Care & Internal Med, San Diego, CA 92134 USA. RP Smith, JD (reprint author), USN, San Diego Med Ctr, Dept Pulm, 34800 Bob Wilson Dr, San Diego, CA 92134 USA. NR 13 TC 0 Z9 0 U1 0 U2 0 PU ASSOC MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA SN 0026-4075 J9 MIL MED JI Milit. Med. PD AUG PY 2011 VL 176 IS 8 BP 956 EP 958 PG 3 WC Medicine, General & Internal SC General & Internal Medicine GA 804TB UT WOS:000293675800020 PM 21882790 ER PT J AU Fraser, MR Sechriest, VF AF Fraser, Michael R., Jr. Sechriest, V. Franklin, II TI Total Knee Arthroplasty in a Patient With Pseudopseudohypoparathyroidism SO ORTHOPEDICS LA English DT Article C1 [Sechriest, V. Franklin, II] USN, Dept Orthoped Surg, San Diego Med Ctr, San Diego, CA 92134 USA. RP Sechriest, VF (reprint author), USN, Dept Orthoped Surg, San Diego Med Ctr, 34800 Bob Wilson Dr, San Diego, CA 92134 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 USA SN 0147-7447 J9 ORTHOPEDICS JI Orthopedics PD AUG PY 2011 VL 34 IS 8 BP 620 EP 620 DI 10.3928/01477447-20110627-30 PG 1 WC Orthopedics SC Orthopedics GA 808OR UT WOS:000293988800028 ER PT J AU Johnson, WB Barnett, JE AF Johnson, W. Brad Barnett, Jeffrey E. TI Preventing Problems of Professional Competence in the Face of Life-Threatening Illness SO PROFESSIONAL PSYCHOLOGY-RESEARCH AND PRACTICE LA English DT Article DE ethics; professional; illness; psychologist; life-threatening ID NATIONAL SURVEY; PSYCHOLOGISTS; IMPAIRMENT; THERAPISTS; DISTRESS; IMPACT; SELF; PSYCHOTHERAPISTS; PRINCIPLES; BELIEFS AB When a psychologist is diagnosed with a serious medical condition and faces the prospect of an arduous treatment regimen and perhaps a bleak prognosis, it may be difficult to attend to one's level of professional competence. Like their clients, psychologists are vulnerable to distress and diminished functioning caused by a life-threatening illness. Psychologists have an ethical responsibility to monitor and ensure professional competence, yet the distress and distraction that accompany serious health problems can inhibit and undermine self-assessments of competence in many ways; distressed psychologists may react with denial, shame, fear, and problematic countertransference responses. The limitations associated with evaluating competence in the context of distress are discussed and several recommendations are offered for psychologists who deliver services, support gravely ill colleagues, and serve in credentialing and regulatory capacities. C1 [Johnson, W. Brad] USN Acad, Dept Leadership Eth & Law, Annapolis, MD 21402 USA. [Barnett, Jeffrey E.] Loyola Univ Maryland, Baltimore, MD USA. RP Johnson, WB (reprint author), USN Acad, Dept Leadership Eth & Law, Luce Hall 7B, Annapolis, MD 21402 USA. EM johnsonb@usna.edu OI Barnett, Jeffrey/0000-0003-0664-4168 NR 49 TC 5 Z9 5 U1 2 U2 5 PU AMER PSYCHOLOGICAL ASSOC PI WASHINGTON PA 750 FIRST ST NE, WASHINGTON, DC 20002-4242 USA SN 0735-7028 EI 1939-1323 J9 PROF PSYCHOL-RES PR JI Prof. Psychol.-Res. Pract. PD AUG PY 2011 VL 42 IS 4 BP 285 EP 293 DI 10.1037/a0024433 PG 9 WC Psychology, Multidisciplinary SC Psychology GA 808DZ UT WOS:000293958200001 ER PT J AU Hanafi, HA Fryauff, DJ Saad, MD Soliman, AK Mohareb, EW Medhat, I Zayed, AB Szumlas, DE Earhart, KC AF Hanafi, Hanafi A. Fryauff, David J. Saad, Magdi D. Soliman, Atef K. Mohareb, Emad W. Medhat, Iman Zayed, Abdel Basset Szumlas, Daniel E. Earhart, Kenneth C. TI Virus isolations and high population density implicate Culex antennatus (Becker) (Diptera: Culicidae) as a vector of Rift Valley Fever virus during an outbreak in the Nile Delta of Egypt SO ACTA TROPICA LA English DT Article DE Culex antennatus; Vector; Rift Valley fever virus; RVFV; Outbreak; Egypt ID HOST-FEEDING PATTERNS; WEST-NILE; MOSQUITOS DIPTERA; EPIDEMIC; TRANSMISSION; GOVERNORATE; RECURRENCE; MAURITANIA; PIPIENS; KENYA AB In June, 2003, Egypt's hospital-based electronic disease surveillance system began to record increased cases of acute febrile illness from governorates in the Nile Delta. In response to a request for assistance from the Egyptian Ministry of Health and the World Health Organization (WHO), the U.S. Naval Medical Research Unit No. 3 (NAMRU-3) provided assistance in identifying the cause and extent of this outbreak. Testing of human clinical samples (n=375) from nine governorates in Egypt identified 29 cases of RVF viremia that spanned the period of June to October, and a particular focus of disease in Kafr el Sheikh governorate (7.7% RVF infection rate). Veterinary samples (n=101) collected during this time in Kafr el Sheikh and screened by immunoassay for RVFV-specific IgM identified probable recent infections in cattle (10.4%) and sheep (5%). Entomologic investigations that focused in rural, rice growing villages in the Sidi Salim District of Kafr el Sheikh during August-September, 2003, collected, identified, and tested host-seeking female mosquitoes for the presence of pathogenic viruses. Three isolates of RVF virus (RVFV) were obtained from 297 tested pools of female mosquitoes and all three RVFV isolates came from Cx. antennatus (Becker). While Cx. pipiens has been considered the primary vector of RVF virus in Egypt and is often the most common man-biting species found, Cx. antennatus was the dominant species captured at the 2003 outbreak location in Kafr el Sheikh governorate. This is the first time that Cx. antennatus has been found naturally infected with RVFV in Egypt. Published by Elsevier B.V. C1 [Hanafi, Hanafi A.; Fryauff, David J.; Saad, Magdi D.; Soliman, Atef K.; Mohareb, Emad W.; Medhat, Iman; Zayed, Abdel Basset; Szumlas, Daniel E.; Earhart, Kenneth C.] USN, Med Res Unit 3, Cairo, Egypt. RP Fryauff, DJ (reprint author), USN, Med Res Ctr, Inst Review Board, Mil Malaria Vaccine Program, 503 Robert Grant Ave, Silver Spring, MD 20910 USA. EM david.fryauff@med.navy.mil RI Saad, Magdi/H-5561-2013 OI Saad, Magdi/0000-0003-2111-8115 FU U.S. Department of Defense Global Emerging Infections Surveillance and Response System (GEIS) FX The authors thank Jonathan Truong for producing the map of the Nile Delta and Maria Badra for administrative assistance. The views expressed in this article are those of the authors and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, nor the U.S. Government. Three co-authors are military service members, the first author and other co-authors are employees of the U.S. Government. This work was prepared as part of their official duties. Title 17 U.S.C. 105 provides that 'Copyright protection under this title is not available for any work of the United States Government'. Title 17 U.S.C. 101 defines a U.S. Government work as a work prepared by a military service member or employee of the U.S. Government as part of that person's official duties. This work was a part of the 2003 Rift Valley fever Outbreak investigation facilitated by funding from the U.S. Department of Defense Global Emerging Infections Surveillance and Response System (GEIS). NR 35 TC 10 Z9 10 U1 1 U2 9 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0001-706X J9 ACTA TROP JI Acta Trop. PD AUG PY 2011 VL 119 IS 2-3 BP 119 EP 124 DI 10.1016/j.actatropica.2011.04.018 PG 6 WC Parasitology; Tropical Medicine SC Parasitology; Tropical Medicine GA 805HJ UT WOS:000293717200009 PM 21570939 ER PT J AU Hunter, L Bormann, J Belding, W Sobo, EJ Axman, L Reseter, BK Hanson, SM Anderson, VM AF Hunter, Lauren Bormann, Jill Belding, Wendy Sobo, Elisa J. Axman, Linnea Reseter, Brenda K. Hanson, Suzanne M. Anderson, Veronica Miranda TI Satisfaction and use of a spiritually based mantram intervention for childbirth-related fears in couples SO APPLIED NURSING RESEARCH LA English DT Article ID POSTTRAUMATIC-STRESS-DISORDER; RANDOMIZED CONTROLLED-TRIAL; WOMEN; MEDITATION; HIV AB This study assessed patient satisfaction with the use of a spiritually based (mantram/sacred word) intervention in expecting couples. A mixed-methods design, experimental repeated measures with interviews at 6-month follow-up was conducted. Satisfaction was moderate to high. Mantram was used for labor pains and uncertainty. Implications include scheduling flexible classes earlier in pregnancy. A larger randomized study is needed to assess intervention effectiveness. (C) 2011 Elsevier Inc. All rights reserved. C1 [Hunter, Lauren; Bormann, Jill] San Diego State Univ, Sch Nursing, San Diego, CA 92182 USA. [Bormann, Jill; Belding, Wendy] VA San Diego Healthcare Syst, San Diego, CA 92161 USA. [Sobo, Elisa J.] San Diego State Univ, Dept Anthropol, San Diego, CA 92182 USA. [Axman, Linnea] USN, Sch Hlth Sci, San Diego, CA 92134 USA. [Reseter, Brenda K.] Bremerton Naval Hosp, OB GYN Dept, Bremerton, WA 98312 USA. [Hanson, Suzanne M.] Maricopa Integrated Hlth Syst, Phoenix, AZ 85008 USA. RP Hunter, L (reprint author), San Diego State Univ, Sch Nursing, San Diego, CA 92182 USA. EM lhunter@mail.sdsu.edu; jill.bormann@va.gov; esobo@mail.sdsu.edu; linnea.axman@med.navy.mil; brenda.reseter@med.navy.mil; suzanne_hanson@medprodoctors.com; vmiranda95@gmail.com NR 32 TC 2 Z9 2 U1 0 U2 9 PU W B SAUNDERS CO-ELSEVIER INC PI PHILADELPHIA PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA SN 0897-1897 J9 APPL NURS RES JI Appl. Nurs. Res. PD AUG PY 2011 VL 24 IS 3 BP 138 EP 146 DI 10.1016/j.apnr.2009.06.002 PG 9 WC Nursing SC Nursing GA 804QW UT WOS:000293670100002 PM 20974063 ER PT J AU Abdo, AA Ackermann, M Ajello, M Baldini, L Ballet, J Barbiellini, G Bastieri, D Bechtol, K Bellazzini, R Berenji, B Blandford, RD Bloom, ED Bonamente, E Borgland, AW Bouvier, A Bregeon, J Brez, A Brigida, M Bruel, P Buehler, R Buson, S Caliandro, GA Cameron, RA Cannon, A Caraveo, PA Carrigan, S Casandjian, JM Cavazzuti, E Cecchi, C Celik, O Charles, E Chekhtman, A Chiang, J Ciprini, S Claus, R Cohen-Tanugi, J Conrad, J Cutini, S de Angelis, A de Palma, F Dermer, CD Silva, EDE Drell, PS Dubois, R Dumora, D Escande, L Favuzzi, C Fegan, SJ Finke, J Focke, WB Fortin, P Frailis, M Fuhrmann, L Fukazawa, Y Fukuyama, T Funk, S Fusco, P Gargano, F Gasparrini, D Gehrels, N Georganopoulos, M Germani, S Giebels, B Giglietto, N Giommi, P Giordano, F Giroletti, M Glanzman, T Godfrey, G Grenier, IA Guiriec, S Hadasch, D Hayashida, M Hays, E Horan, D Hughes, RE Johannesson, G Johnson, AS Johnson, WN Kadler, M Kamae, T Katagiri, H Kataoka, J Knodlseder, J Kuss, M Lande, J Latronico, L Lee, SH Longo, F Loparco, F Lott, B Lovellette, MN Lubrano, P Madejski, GM Makeev, A Max-Moerbeck, W Mazziotta, MN McEnery, JE Mehault, J Michelson, PF Mitthumsiri, W Mizuno, T Monte, C Monzani, ME Morselli, A Moskalenko, IV Murgia, S Nakamori, T Naumann-Godo, M Nishino, S Nolan, PL Norris, JP Nuss, E Ohsugi, T Okumura, A Omodei, N Orlando, E Ormes, JF Ozaki, M Paneque, D Panetta, JH Parent, D Pavlidou, V Pearson, TJ Pelassa, V Pepe, M Pesce-Rollins, M Pierbattista, M Piron, F Porter, TA Raino, S Rando, R Razzano, M Readhead, A Reimer, A Reimer, O Reyes, LC Richards, JL Ritz, S Roth, M Sadrozinski, HFW Sanchez, D Sander, A Sgro, C Siskind, EJ Smith, PD Spandre, G Spinelli, P Stawarz, L Stevenson, M Strickman, MS Suson, DJ Takahashi, H Takahashi, T Tanaka, T Thayer, JG Thayer, JB Thompson, DJ Tibaldo, L Torres, DF Tosti, G Tramacere, A Troja, E Usher, TL Vandenbroucke, J Vasileiou, V Vianello, G Vilchez, N Vitale, V Waite, AP Wang, P Wehrle, AE Winer, BL Wood, KS Yang, Z Yatsu, Y Ylinen, T Zensus, JA Ziegler, M Aleksic, J Antonelli, LA Antoranz, P Backes, M Barrio, JA Gonzalez, JB Bednarek, W Berdyugin, A Berger, K Bernardini, E Biland, A Blanch, O Bock, RK Boller, A Bonnoli, G Bordas, P Tridon, DB Bosch-Ramon, V Bose, D Braun, I Bretz, T Camara, M Carmona, E Carosi, A Colin, P Colombo, E Contreras, JL Cortina, J Covino, S Dazzi, F de Angelis, A del Pozo, ED Mendez, CD De Lotto, B De Maria, M De Sabata, F Ortega, AD Doert, M Dominguez, A Prester, DD Dorner, D Doro, M Elsaesser, D Ferenc, D Fonseca, MV Font, L Lopez, RJG Garczarczyk, M Gaug, M Giavitto, G Godinovi, N Hadasch, D Herrero, A Hildebrand, D Hohne-Monch, D Hose, J Hrupec, D Jogler, T Klepser, S Krahenbuhl, T Kranich, D Krause, J La Barbera, A Leonardo, E Lindfors, E Lombardi, S Lopez, M Lorenz, E Majumdar, P Makariev, E Maneva, G Mankuzhiyil, N Mannheim, K Maraschi, L Mariotti, M Martinez, M Mazin, D Meucci, M Miranda, JM Mirzoyan, R Miyamoto, H Moldon, J Moralejo, A Nieto, D Nilsson, K Orito, R Oya, I Paoletti, R Paredes, JM Partini, S Pasanen, M Pauss, F Pegna, RG Perez-Torres, MA Persic, M Peruzzo, J Pochon, J Prada, F Moroni, PGP Prandini, E Puchades, N Puljak, I Reichardt, T Rhode, W Ribo, M Rico, J Rissi, M Rugamer, S Saggion, A Saito, K Saito, TY Salvati, M Sanchez-Conde, M Satalecka, K Scalzotto, V Scapin, V Schultz, C Schweizer, T Shayduk, M Shore, SN Sierpowska-Bartosik, A Sillanpaa, A Sitarek, J Sobczynska, D Spanier, F Spiro, S Stamerra, A Steinke, B Storz, J Strah, N Struebig, JC Suric, T Takalo, LO Tavecchio, F Temnikov, P Terzic, T Tescaro, D Teshima, M Vankov, H Wagner, RM Weitzel, Q Zabalza, V Zandanel, F Zanin, R Villata, M Raiteri, C Aller, HD Aller, MF Chen, WP Jordan, B Koptelova, E Kurtanidze, OM Lahteenmaki, A McBreen, B Larionov, VM Lin, CS Nikolashvili, MG Reinthal, R Angelakis, E Capalbi, M Carraminana, A Carrasco, L Cassaro, P Cesarini, A Falcone, A Gurwell, MA Hovatta, T Kovalev, YA Kovalev, YY Krichbaum, TP Krimm, HA Lister, ML Moody, JW Maccaferri, G Mori, Y Nestoras, I Orlati, A Pace, C Pagani, C Pearson, R Perri, M Piner, BG Ros, E Sadun, AC Sakamoto, T Tammi, J Zook, A AF Abdo, A. A. Ackermann, M. Ajello, M. Baldini, L. Ballet, J. Barbiellini, G. Bastieri, D. Bechtol, K. Bellazzini, R. Berenji, B. Blandford, R. D. Bloom, E. D. Bonamente, E. Borgland, A. W. Bouvier, A. Bregeon, J. Brez, A. Brigida, M. Bruel, P. Buehler, R. Buson, S. Caliandro, G. A. Cameron, R. A. Cannon, A. Caraveo, P. A. Carrigan, S. Casandjian, J. M. Cavazzuti, E. Cecchi, C. Celik, Oe. Charles, E. Chekhtman, A. Chiang, J. Ciprini, S. Claus, R. Cohen-Tanugi, J. Conrad, J. Cutini, S. de Angelis, A. de Palma, F. Dermer, C. D. do Couto e Silva, E. Drell, P. S. Dubois, R. Dumora, D. Escande, L. Favuzzi, C. Fegan, S. J. Finke, J. Focke, W. B. Fortin, P. Frailis, M. Fuhrmann, L. Fukazawa, Y. Fukuyama, T. Funk, S. Fusco, P. Gargano, F. Gasparrini, D. Gehrels, N. Georganopoulos, M. Germani, S. Giebels, B. Giglietto, N. Giommi, P. Giordano, F. Giroletti, M. Glanzman, T. Godfrey, G. Grenier, I. A. Guiriec, S. Hadasch, D. Hayashida, M. Hays, E. Horan, D. Hughes, R. E. Johannesson, G. Johnson, A. S. 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Takalo, L. O. Tavecchio, F. Temnikov, P. Terzic, T. Tescaro, D. Teshima, M. Vankov, H. Wagner, R. M. Weitzel, Q. Zabalza, V. Zandanel, F. Zanin, R. Villata, M. Raiteri, C. Aller, H. D. Aller, M. F. Chen, W. P. Jordan, B. Koptelova, E. Kurtanidze, O. M. Lahteenmaki, A. McBreen, B. Larionov, V. M. Lin, C. S. Nikolashvili, M. G. Reinthal, R. Angelakis, E. Capalbi, M. Carraminana, A. Carrasco, L. Cassaro, P. Cesarini, A. Falcone, A. Gurwell, M. A. Hovatta, T. Kovalev, Yu A. Kovalev, Y. Y. Krichbaum, T. P. Krimm, H. A. Lister, M. L. Moody, J. W. Maccaferri, G. Mori, Y. Nestoras, I. Orlati, A. Pace, C. Pagani, C. Pearson, R. Perri, M. Piner, B. G. Ros, E. Sadun, A. C. Sakamoto, T. Tammi, J. Zook, A. CA Fermi-LAT Collaboration MAGIC Collaboration TI FERMI LARGE AREA TELESCOPE OBSERVATIONS OF MARKARIAN 421: THE MISSING PIECE OF ITS SPECTRAL ENERGY DISTRIBUTION SO ASTROPHYSICAL JOURNAL LA English DT Article DE acceleration of particles; BL Lacertae objects: general; BL Lacertae objects: individual (Mrk 421); galaxies: active; gamma rays: general; radiation mechanisms: non-thermal ID BL-LACERTAE OBJECTS; X-RAY-SPECTRA; ACTIVE GALAXY MARKARIAN-421; TEV BLAZAR MARKARIAN-421; LOG-PARABOLIC SPECTRA; BLACK-HOLE MASSES; MULTIWAVELENGTH OBSERVATIONS; RADIO-SOURCES; CRAB-NEBULA; 3C 454.3 AB We report on the gamma-ray activity of the high-synchrotron-peaked BL Lacertae object Markarian 421 (Mrk 421) during the first 1.5 years of Fermi operation, from 2008 August 5 to 2010 March 12. We find that the Large Area Telescope (LAT) gamma-ray spectrum above 0.3 GeV can be well described by a power-law function with photon index Gamma = 1.78 +/- 0.02 and average photon flux F(>0.3 GeV) = (7.23 +/- 0.16) x 10(-8) ph cm(-2) s(-1). Over this time period, the Fermi-LAT spectrum above 0.3 GeV was evaluated on seven-day-long time intervals, showing significant variations in the photon flux (up to a factor similar to 3 from the minimum to the maximum flux) but mild spectral variations. The variability amplitude at X-ray frequencies measured by RXTE/ASM and Swift/BAT is substantially larger than that in gamma-rays measured by Fermi-LAT, and these two energy ranges are not significantly correlated. We also present the first results from the 4.5 month long multifrequency campaign on Mrk 421, which included the VLBA, Swift, RXTE, MAGIC, the F-GAMMA, GASP-WEBT, and other collaborations and instruments that provided excellent temporal and energy coverage of the source throughout the entire campaign (2009 January 19 to 2009 June 1). During this campaign, Mrk 421 showed a low activity at all wavebands. The extensive multi-instrument (radio to TeV) data set provides an unprecedented, complete look at the quiescent spectral energy distribution (SED) for this source. The broadband SED was reproduced with a leptonic (one-zone synchrotron self-Compton) and a hadronic model (synchrotron proton blazar). Both frameworks are able to describe the average SED reasonably well, implying comparable jet powers but very different characteristics for the blazar emission site. C1 [Abdo, A. A.] Natl Acad Sci, Natl Res Council Res Associate, Washington, DC 20001 USA. 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[Vitale, V.] Univ Roma Tor Vergata, Dipartimento Fis, I-00133 Rome, Italy. [Wehrle, A. E.] Space Sci Inst, Boulder, CO 80301 USA. [Yatsu, Y.; Mori, Y.] Tokyo Inst Technol, Dept Phys, Meguro, Tokyo 1528551, Japan. [Ylinen, T.] Royal Inst Technol KTH, Dept Phys, SE-10691 Stockholm, Sweden. [Ylinen, T.] Univ Kalmar, Sch Pure & Appl Nat Sci, SE-39182 Kalmar, Sweden. [Aleksic, J.; Blanch, O.; Cortina, J.; Giavitto, G.; Klepser, S.; Martinez, M.; Mazin, D.; Moralejo, A.; Puchades, N.; Reichardt, T.; Rico, J.; Tescaro, D.; Zanin, R.] Univ Autonoma Barcelona, IFAE, E-08193 Bellaterra, Barcelona, Spain. [Antonelli, L. A.; Bonnoli, G.; Carosi, A.; Covino, S.; La Barbera, A.; Salvati, M.; Spiro, S.] INAF Natl Inst Astrophys, I-00136 Rome, Italy. [Antoranz, P.; Leonardo, E.; Meucci, M.; Miranda, J. M.; Paoletti, R.; Partini, S.; Pegna, R. G.; Moroni, P. G. Prada; Stamerra, A.] Univ Siena, I-53100 Siena, Italy. [Antoranz, P.; Leonardo, E.; Meucci, M.; Miranda, J. M.; Paoletti, R.; Partini, S.; Pegna, R. G.; Moroni, P. G. Prada; Stamerra, A.] INFN Pisa, I-53100 Siena, Italy. [Backes, M.; Doert, M.; Rhode, W.; Strah, N.] Tech Univ Dortmund, D-44221 Dortmund, Germany. [Barrio, J. A.; Bose, D.; Camara, M.; Contreras, J. L.; Fonseca, M. V.; Nieto, D.; Oya, I.] Univ Complutense, E-28040 Madrid, Spain. [Becerra Gonzalez, J.; Colombo, E.; Delgado Mendez, C.; Diago Ortega, A.; Garcia Lopez, R. J.; Garczarczyk, M.; Gaug, M.; Herrero, A.; Pochon, J.; Sanchez-Conde, M.] Inst Astrofis Canarias, E-38205 San Cristobal la Laguna, Tenerife, Spain. [Becerra Gonzalez, J.; Berger, K.; Diago Ortega, A.; Garcia Lopez, R. J.; Herrero, A.; Sanchez-Conde, M.] Univ La Laguna, Dept Astrofis, E-38205 Tenerife, Spain. [Bednarek, W.; Sierpowska-Bartosik, A.; Sitarek, J.; Sobczynska, D.] Univ Lodz, PL-90236 Lodz, Poland. [Berdyugin, A.; Lindfors, E.; Pasanen, M.; Sillanpaa, A.; Takalo, L. O.; Reinthal, R.] Univ Turku, Tuorla Observ, FI-21500 Piikkio, Finland. [Bernardini, E.; Majumdar, P.; Satalecka, K.] Deutsch Elektronen Synchrotron DESY, D-15738 Zeuthen, Germany. [Biland, A.; Boller, A.; Braun, I.; Dorner, D.; Hildebrand, D.; Kraehenbuehl, T.; Kranich, D.; Lorenz, E.; Pauss, F.; Rissi, M.; Weitzel, Q.] ETH, CH-8093 Zurich, Switzerland. [Bordas, P.; Bosch-Ramon, V.; Moldon, J.; Paredes, J. M.; Ribo, M.; Zabalza, V.] Univ Barcelona ICC IEEC, E-08028 Barcelona, Spain. [Bretz, T.; Elsaesser, D.; Hoehne-Moench, D.; Mannheim, K.; Ruegamer, S.; Spanier, F.; Storz, J.; Struebig, J. C.] Univ Wurzburg, Inst Theoret Phys & Astrophys, D-97074 Wurzburg, Germany. [Delgado Mendez, C.] Ctr Invest Energet Medioambientales & Tecnol CIEM, Madrid, Spain. [Dominguez, A.; Perez-Torres, M. A.; Prada, F.; Zandanel, F.] CSIC, Inst Astrofis Andalucia, E-18080 Granada, Spain. [Prester, D. Dominis; Ferenc, D.; Godinovi, N.; Hrupec, D.; Puljak, I.; Suric, T.; Terzic, T.] Univ Rijeka, Inst R Boskovic, Croatian MAGIC Consortium, HR-10000 Zagreb, Croatia. [Prester, D. Dominis; Ferenc, D.; Godinovi, N.; Hrupec, D.; Puljak, I.; Suric, T.; Terzic, T.] Univ Split, HR-10000 Zagreb, Croatia. [Font, L.] Univ Autonoma Barcelona, E-08193 Bellaterra, Spain. [Makariev, E.; Maneva, G.; Temnikov, P.; Vankov, H.] Inst Nucl Energy Res, BG-1784 Sofia, Bulgaria. [Maraschi, L.; Tavecchio, F.] INAF Osservatorio Astron Brera, I-23807 Merate, Italy. [Nilsson, K.] Univ Turku, Finnish Ctr Astron ESO FINCA, FI-21500 Piikiio, Finland. [Persic, M.] INAF Osservatorio Astron Trieste, I-34143 Trieste, Italy. [Shore, S. N.] Univ Pisa, Dipartimento Fis Enrico Fermi, I-56127 Pisa, Italy. [Villata, M.; Raiteri, C.] Osserv Astron Torino, INAF, I-10025 Pino Torinese, TO, Italy. [Aller, H. D.; Aller, M. F.] Univ Michigan, Dept Astron, Ann Arbor, MI 48109 USA. [Chen, W. P.; Koptelova, E.; Lin, C. S.] Natl Cent Univ, Grad Inst Astron, Jhongli 32054, Taiwan. [Jordan, B.] Dublin Inst Adv Studies, Sch Cosm Phys, Dublin 2, Ireland. [Lahteenmaki, A.; Hovatta, T.; Tammi, J.] Abastumani Observ, GE-0301 Abastumani, Rep of Georgia. [Larionov, V. M.] Isaac Newton Inst Chile, St Petersburg Branch, St Petersburg, Russia. [Larionov, V. M.] Pulkovo Observ, St Petersburg 196140, Russia. [Larionov, V. M.] St Petersburg State Univ, Astron Inst, St Petersburg, Russia. [Carraminana, A.; Carrasco, L.] Inst Nacl Astrofis Opt & Electr, Puebla 72840, Mexico. [Cassaro, P.] INAF Ist Radioastron, Sez Noto, I-96017 Noto, SR, Italy. [Cesarini, A.] Natl Univ Ireland Galway, Dept Phys, Galway, Ireland. [Falcone, A.] Penn State Univ, Dept Astron & Astrophys, University Pk, PA 16802 USA. [Gurwell, M. A.] Harvard Smithsonian Ctr Astrophys, Cambridge, MA 02138 USA. [Kovalev, Yu A.; Kovalev, Y. Y.] Lebedev Phys Inst, Ctr Astro Space, Moscow 117997, Russia. [Lister, M. L.] Purdue Univ, Dept Phys, W Lafayette, IN 47907 USA. [Moody, J. W.; Pace, C.; Pearson, R.] Brigham Young Univ, Dept Phys & Astron, Provo, UT 84602 USA. [Maccaferri, G.; Orlati, A.] INAF Ist Radioastron, Stn Radioastron Med, I-40059 Bologna, Italy. [Pagani, C.] Univ Leicester, Dept Phys & Astron, Leicester LE1 7RH, Leics, England. [Piner, B. G.] Whittier Coll, Dept Phys & Astron, Whittier, CA USA. [Ros, E.] Univ Valencia, Valencia 46010, Spain. [Sadun, A. C.] Univ Colorado, Dept Phys, Denver, CO 80220 USA. [Zook, A.] Pomona Coll, Dept Phys & Astron, Claremont, CA 91711 USA. RP Abdo, AA (reprint author), Natl Acad Sci, Natl Res Council Res Associate, Washington, DC 20001 USA. EM justin.finke@nrl.navy.mil; dpaneque@mppmu.mpg.de; anita.reimer@uibk.ac.at RI Fonseca Gonzalez, Maria Victoria/I-2004-2015; Tosti, Gino/E-9976-2013; Larionov, Valeri/H-1349-2013; Ozaki, Masanobu/K-1165-2013; Rando, Riccardo/M-7179-2013; Lahteenmaki, Anne/L-5987-2013; Hays, Elizabeth/D-3257-2012; Johnson, Neil/G-3309-2014; Kurtanidze, Omar/J-6237-2014; Rico, Javier/K-8004-2014; Fernandez, Ester/K-9734-2014; Lopez Moya, Marcos/L-2304-2014; GAug, Markus/L-2340-2014; Moralejo Olaizola, Abelardo/M-2916-2014; Ribo, Marc/B-3579-2015; Baldini, Luca/E-5396-2012; Mannheim, Karl/F-6705-2012; lubrano, pasquale/F-7269-2012; Kuss, Michael/H-8959-2012; Doro, Michele/F-9458-2012; giglietto, nicola/I-8951-2012; Reimer, Olaf/A-3117-2013; Morselli, Aldo/G-6769-2011; Prada Moroni, Pier Giorgio/G-5565-2011; Braun, Isabel/C-9373-2012; Thompson, David/D-2939-2012; Gehrels, Neil/D-2971-2012; McEnery, Julie/D-6612-2012; Font, Lluis/L-4197-2014; Moskalenko, Igor/A-1301-2007; Contreras Gonzalez, Jose Luis/K-7255-2014; Mazziotta, Mario /O-8867-2015; Sgro, Carmelo/K-3395-2016; Maneva, Galina/L-7120-2016; Backes, Michael/N-5126-2016; Torres, Diego/O-9422-2016; Temnikov, Petar/L-6999-2016; Orlando, E/R-5594-2016; Barrio, Juan/L-3227-2014; Cortina, Juan/C-2783-2017; Kovalev, Yuri/J-5671-2013; Funk, Stefan/B-7629-2015; Pavlidou, Vasiliki/C-2944-2011; Antoranz, Pedro/H-5095-2015; Delgado, Carlos/K-7587-2014; Nieto, Daniel/J-7250-2015; Kovalev, Yuri/N-1053-2015; Pearson, Timothy/N-2376-2015; Loparco, Francesco/O-8847-2015; Gargano, Fabio/O-8934-2015; Johannesson, Gudlaugur/O-8741-2015; Miranda, Jose Miguel/F-2913-2013 OI Becerra Gonzalez, Josefa/0000-0002-6729-9022; Cesarini, Andrea/0000-0002-8611-8610; leonardo, elvira/0000-0003-0271-7673; Villata, Massimo/0000-0003-1743-6946; Fonseca Gonzalez, Maria Victoria/0000-0003-2235-0725; Caraveo, Patrizia/0000-0003-2478-8018; De Lotto, Barbara/0000-0003-3624-4480; Sgro', Carmelo/0000-0001-5676-6214; SPINELLI, Paolo/0000-0001-6688-8864; Rando, Riccardo/0000-0001-6992-818X; Persic, Massimo/0000-0003-1853-4900; Spanier, Felix/0000-0001-6802-4744; Raiteri, Claudia Maria/0000-0003-1784-2784; Ros, Eduardo/0000-0001-9503-4892; Cassaro, Pietro/0000-0001-5139-9662; Orlati, Andrea/0000-0001-8737-255X; Prada Moroni, Pier Giorgio/0000-0001-9712-9916; giommi, paolo/0000-0002-2265-5003; De Angelis, Alessandro/0000-0002-3288-2517; Frailis, Marco/0000-0002-7400-2135; Larionov, Valeri/0000-0002-4640-4356; Rico, Javier/0000-0003-4137-1134; Lopez Moya, Marcos/0000-0002-8791-7908; GAug, Markus/0000-0001-8442-7877; Moralejo Olaizola, Abelardo/0000-0002-1344-9080; lubrano, pasquale/0000-0003-0221-4806; Doro, Michele/0000-0001-9104-3214; giglietto, nicola/0000-0002-9021-2888; Reimer, Olaf/0000-0001-6953-1385; Morselli, Aldo/0000-0002-7704-9553; Braun, Isabel/0000-0002-9389-0502; Thompson, David/0000-0001-5217-9135; Bonnoli, Giacomo/0000-0003-2464-9077; Stamerra, Antonio/0000-0002-9430-5264; Prandini, Elisa/0000-0003-4502-9053; Kadler, Matthias/0000-0001-5606-6154; Covino, Stefano/0000-0001-9078-5507; Bordas, Pol/0000-0002-0266-8536; Cutini, Sara/0000-0002-1271-2924; Paredes, Josep M./0000-0002-1566-9044; Oya, Igor/0000-0002-3881-9324; Berenji, Bijan/0000-0002-4551-772X; Gasparrini, Dario/0000-0002-5064-9495; Tramacere, Andrea/0000-0002-8186-3793; Baldini, Luca/0000-0002-9785-7726; Dominguez, Alberto/0000-0002-3433-4610; Bastieri, Denis/0000-0002-6954-8862; Omodei, Nicola/0000-0002-5448-7577; Ribo, Marc/0000-0002-9931-4557; Pesce-Rollins, Melissa/0000-0003-1790-8018; Giroletti, Marcello/0000-0002-8657-8852; Perri, Matteo/0000-0003-3613-4409; Angelakis, Emmanouil/0000-0001-7327-5441; Font, Lluis/0000-0003-2109-5961; Moskalenko, Igor/0000-0001-6141-458X; Contreras Gonzalez, Jose Luis/0000-0001-7282-2394; Mazziotta, Mario /0000-0001-9325-4672; Backes, Michael/0000-0002-9326-6400; Torres, Diego/0000-0002-1522-9065; Temnikov, Petar/0000-0002-9559-3384; Barrio, Juan/0000-0002-0965-0259; Cortina, Juan/0000-0003-4576-0452; Kovalev, Yuri/0000-0001-9303-3263; Funk, Stefan/0000-0002-2012-0080; Pavlidou, Vasiliki/0000-0002-0870-1368; Antoranz, Pedro/0000-0002-3015-3601; Delgado, Carlos/0000-0002-7014-4101; Nieto, Daniel/0000-0003-3343-0755; Pearson, Timothy/0000-0001-5213-6231; Loparco, Francesco/0000-0002-1173-5673; Gargano, Fabio/0000-0002-5055-6395; Johannesson, Gudlaugur/0000-0003-1458-7036; Miranda, Jose Miguel/0000-0002-1472-9690 FU Academy of Finland [212656, 210338]; Russian RFBR foundation [09-02-00092]; RFBR [08-02-00545]; NASA [NNX08AW31G]; NSF [AST-0808050]; Smithsonian Institution; Academia Sinica; Georgian National Science Foundation [GNSF/ST07/4-180] FX We acknowledge the use of public data from the Swift and RXTE data archives. The Metsahovi team acknowledges the support from the Academy of Finland for the observing projects (numbers 212656, 210338, among others). This research has made use of data obtained from the National Radio Astronomy Observatory's Very Long Baseline Array (VLBA), projects BK150, BP143, and BL149 (MOJAVE). The National Radio Astronomy Observatory is a facility of the National Science Foundation operated under cooperative agreement by Associated Universities, Inc. The St. Petersburg University team acknowledges support from the Russian RFBR foundation via grant 09-02-00092. AZT-24 observations are made within an agreement between Pulkovo, Rome and Teramo observatories. This research is partly based on observations with the 100 m telescope of the MPIfR (Max-Planck-Institut fur Radioastronomie) at Effelsberg, as well as with the Medicina and Noto telescopes operated by INAF-Istituto di Radioastronomia. RATAN-600 observations were supported in part by the RFBR grant 08-02-00545 and the OVRO 40 m program was funded in part by NASA (NNX08AW31G) and the NSF (AST-0808050). The Submillimeter Array is a joint project between the Smithsonian Astrophysical Observatory and the Academia Sinica Institute of Astronomy and Astrophysics and is funded by the Smithsonian Institution and the Academia Sinica. M. Villata organized the optical-to-radio observations by GASP-WEBT as the president of the collaboration. The Abastumani Observatory team acknowledges financial support by the Georgian National Science Foundation through grant GNSF/ST07/4-180. NR 102 TC 105 Z9 106 U1 1 U2 28 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X EI 1538-4357 J9 ASTROPHYS J JI Astrophys. J. PD AUG 1 PY 2011 VL 736 IS 2 AR 131 DI 10.1088/0004-637X/736/2/131 PG 22 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 795MD UT WOS:000292977400056 ER PT J AU Wang, YM Robbrecht, E AF Wang, Y. -M. Robbrecht, E. TI ASYMMETRIC SUNSPOT ACTIVITY AND THE SOUTHWARD DISPLACEMENT OF THE HELIOSPHERIC CURRENT SHEET SO ASTROPHYSICAL JOURNAL LA English DT Article DE interplanetary medium; Sun: activity; Sun: dynamo; Sun: heliosphere; sunspots; Sun: surface magnetism ID MAGNETIC-FIELD; SOLAR-CYCLE; POLAR FIELDS; NORTH; PHOTOSPHERE; EVOLUTION; MINIMUM; CORONA; MODEL AB Observations of the interplanetary magnetic field (IMF) have suggested a statistical tendency for the heliospheric current sheet (HCS) to be shifted a few degrees southward of the heliographic equator during the period 1965-2010, particularly in the years near sunspot minimum. Using potential-field source-surface extrapolations and photospheric flux-transport simulations, we demonstrate that this southward displacement follows from Joy's law and the observed hemispheric asymmetry in the sunspot numbers, with activity being stronger in the southern (northern) hemisphere during the declining (rising) phase of cycles 20-23. The hemispheric asymmetry gives rise to an axisymmetric quadrupole field, whose equatorial zone has the sign of the leading-polarity flux in the dominant hemisphere; during the last four cycles, the polarity of the IMF around the equator thus tended to match that of the north polar field both before and after polar field reversal. However, large fluctuations are introduced by the nonaxisymmetric field components, which depend on the longitudinal distribution of sunspot activity in either hemisphere. Consistent with this model, the HCS showed an average northward displacement during cycle 19, when the "usual" alternation was reversed and the northern hemisphere became far more active than the southern hemisphere during the declining phase of the cycle. We propose a new method for determining the north-south displacement of the HCS from coronal streamer observations. C1 [Wang, Y. -M.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. [Robbrecht, E.] Royal Observ Belgium, B-1180 Brussels, Belgium. RP Wang, YM (reprint author), USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. EM yi.wang@nrl.navy.mil; eva.robbrecht@oma.be FU NASA; Office of Naval Research FX We are indebted to N. R. Sheeley Jr. for stimulating discussions. This work was supported by NASA and the Office of Naval Research. NR 31 TC 13 Z9 14 U1 0 U2 7 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X EI 1538-4357 J9 ASTROPHYS J JI Astrophys. J. PD AUG 1 PY 2011 VL 736 IS 2 AR 136 DI 10.1088/0004-637X/736/2/136 PG 12 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 795MD UT WOS:000292977400061 ER PT J AU Selvaraj, N Shelley, KH Silverman, DG Stachenfeld, N Galante, N Florian, JP Mendelson, Y Chon, KH AF Selvaraj, Nandakumar Shelley, Kirk H. Silverman, David G. Stachenfeld, Nina Galante, Nicholas Florian, John P. Mendelson, Yitzhak Chon, Ki H. TI A Novel Approach Using Time-Frequency Analysis of Pulse-Oximeter Data to Detect Progressive Hypovolemia in Spontaneously Breathing Healthy Subjects SO IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING LA English DT Article DE Blood loss; hypovolemia; lower body negative pressure (LBNP); photoplethysmogram (PPG); pulse oximeter; time-frequency analysis; trauma care ID BODY NEGATIVE-PRESSURE; WAVE-FORM; HEMORRHAGIC-SHOCK; RESPIRATORY RATE; PHOTOPLETHYSMOGRAM; RESPONSES; HUMANS AB Accurate and early detection of blood volume loss would greatly improve intraoperative and trauma care. This study has attempted to determine early diagnostic and quantitative markers for blood volume loss by analyzing photoplethysmogram (PPG) data from ear, finger, and forehead sites with our high-resolution time-frequency spectral (TFS) technique in spontaneously breathing healthy subjects (n = 11) subjected to lower body negative pressure (LBNP). The instantaneous amplitude modulations (AM) present in heart rate (AM(HR)) and breathing rate (AM(BR)) band frequencies of PPG signals were calculated from the high-resolution TFS. Results suggested that the changes (P < 0.05) in AM(BR) and especially in AM(HR) values can be used to detect the blood volume loss at an early stage of 20% LBNP tolerance when compared to the baseline values. The mean percent decrease in AM(HR) values at 100% LBNP tolerance was 78.3%, 72.5%, and 33.9% for ear, finger, and forehead PPG signals, respectively. The mean percent increase in AM(BR) values at 100% LBNP tolerance was 99.4% and 19.6% for ear and finger sites, respectively; AM(BR) values were not attainable for forehead PPG signal. Even without baseline AM(HR) values, our results suggest that hypovolemia detection is possible with specificity and sensitivity greater than 90% for the ear and forehead locations when LBNP tolerance is 100%. Therefore, the TFS analysis of noninvasive PPG waveforms is promising for early diagnosis and quantification of hypovolemia at levels not identified by vital signs in spontaneously breathing subjects. C1 [Selvaraj, Nandakumar; Mendelson, Yitzhak; Chon, Ki H.] Worcester Polytech Inst, Dept Biomed Engn, Worcester, MA 01609 USA. [Shelley, Kirk H.; Silverman, David G.; Galante, Nicholas] Yale Univ, Dept Anesthesiol, New Haven, CT 06520 USA. [Stachenfeld, Nina] John B Pierce Lab, New Haven, CT 06519 USA. [Florian, John P.] USN, Dept Biomed Res & Dev, Expt Diving Unit, Panama City, FL 32407 USA. RP Chon, KH (reprint author), Worcester Polytech Inst, Dept Biomed Engn, Worcester, MA 01609 USA. EM nselvaraj@wpi.edu; kirk.shelley@yale.edu; david.silverman@yale.edu; nstach@jbpierce.org; nicholas.galente@yale.edu; john.florian@navy.mil; ym@wpi.edu; kichon@wpi.edu RI Shelley, Kirk/E-4435-2010 OI Shelley, Kirk/0000-0002-7344-0897 FU Office of Naval Research Work Unit [N00014-08-1-0244] FX Manuscript received January 31, 2011; revised March 17, 2011; accepted April 9, 2011. Date of publication April 21, 2011; date of current version July 20, 2011. This work was supported by the Office of Naval Research Work Unit under Grant N00014-08-1-0244. Asterisk indicates corresponding author. NR 20 TC 11 Z9 11 U1 1 U2 8 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0018-9294 J9 IEEE T BIO-MED ENG JI IEEE Trans. Biomed. Eng. PD AUG PY 2011 VL 58 IS 8 DI 10.1109/TBME.2011.2144981 PG 8 WC Engineering, Biomedical SC Engineering GA 805BI UT WOS:000293700800016 ER PT J AU Olson, CC Nichols, JM Todd, MD Michalowicz, JV Bucholtz, F AF Olson, Colin C. Nichols, Jonathan M. Todd, Michael D. Michalowicz, Joseph V. Bucholtz, Frank TI Coupling Evolutionary Algorithms With Nonlinear Dynamical Systems: An Efficient Tool for Excitation Design and Optimization SO IEEE TRANSACTIONS ON EVOLUTIONARY COMPUTATION LA English DT Article DE Chaos; damage detection; differential evolution; evolutionary algorithms; nonlinear dynamics; phase-locked loops ID CHAOS AB Many chaotic dynamical systems can produce time series with a wide range of temporal and spectral properties as a function of only a few fixed parameters. This malleability invites their use as tools for shaping or designing inputs used to drive a separate dynamical system of interest. By specifying an objective function and employing an evolutionary algorithm to manipulate the parameters governing the dynamics of the forcing system, the output of the driven system is made to approach an optimal response subject to desired constraints. The technique's versatility is demonstrated for two different applications: damage detection in structures and phase-locked loop disruption. C1 [Olson, Colin C.; Nichols, Jonathan M.; Michalowicz, Joseph V.; Bucholtz, Frank] USN, Res Lab, Washington, DC 20375 USA. [Todd, Michael D.] Univ Calif San Diego, Dept Struct Engn, La Jolla, CA 92093 USA. [Michalowicz, Joseph V.] Global Strategies Grp N Amer, Crofton, MD 21114 USA. RP Olson, CC (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM colin.olson.ctr@nrl.navy.mil; jonathan.nichols@nrl.navy.mil; mdt@ucsd.edu; georgiamsa@yahoo.com; frank.bucholtz@nrl.navy.mil FU Naval Research Laboratory through a National Research Council FX The work of C. C. Olson is supported by the Naval Research Laboratory through a National Research Council Post-Doctoral Fellowship. NR 26 TC 0 Z9 0 U1 2 U2 8 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1089-778X J9 IEEE T EVOLUT COMPUT JI IEEE Trans. Evol. Comput. PD AUG PY 2011 VL 15 IS 4 BP 437 EP 443 DI 10.1109/TEVC.2010.2049360 PG 7 WC Computer Science, Artificial Intelligence; Computer Science, Theory & Methods SC Computer Science GA 805PG UT WOS:000293740700001 ER PT J AU Kroonen, LT AF Kroonen, Leo T. TI Hand Made: Redwood-Balsa Hollow Wooden Surfboard SO JOURNAL OF HAND SURGERY-AMERICAN VOLUME LA English DT Editorial Material C1 USN, Div Hand & Microvasc Surg, Dept Orthopaed Surg, San Diego Med Ctr, San Diego, CA 92134 USA. RP Kroonen, LT (reprint author), USN, Div Hand & Microvasc Surg, Dept Orthopaed Surg, San Diego Med Ctr, 34800 Bob Wilson Dr, San Diego, CA 92134 USA. EM leo.kroonen@med.navy.mil NR 0 TC 0 Z9 0 U1 1 U2 3 PU W B SAUNDERS CO-ELSEVIER INC PI PHILADELPHIA PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA SN 0363-5023 J9 J HAND SURG-AM JI J. Hand Surg.-Am. Vol. PD AUG PY 2011 VL 36A IS 8 BP 1370 EP 1370 DI 10.1016/j.jhsa.2011.03.044 PG 1 WC Orthopedics; Surgery SC Orthopedics; Surgery GA 804QP UT WOS:000293669400019 ER PT J AU McDonald, LS Bavaro, MF Hofmeister, EP Kroonen, LT AF McDonald, Lucas S. Bavaro, Mary F. Hofmeister, Eric P. Kroonen, Leo T. TI Hand Infections SO JOURNAL OF HAND SURGERY-AMERICAN VOLUME LA English DT Article DE Infection; MRSA; deep space infection; osteomyelitis; necrotizing fasciitis ID RESISTANT STAPHYLOCOCCUS-AUREUS; CLOSED CONTINUOUS IRRIGATION; NECROTIZING FASCIITIS; ANIMAL BITES; OSTEOMYELITIS; MANAGEMENT; PREVALENCE; WOUNDS AB Hand infections are commonly seen by orthopedic surgeons as well as emergency room and primary care physicians. Identifying the cause of the infection and initiating prompt and appropriate medical or surgical treatment can prevent substantial morbidity. The most common bacteria implicated in hand infections remain Staphylococcus aureus and Streptococcus species. Methicillin-resistant S aureus infections have become prevalent and represent a difficult problem best treated with empiric antibiotic therapy until the organism can be confirmed. Other organisms can be involved in specific situations that will be reviewed. Types of infections include cellulitis, superficial abscesses, deep abscesses, septic arthritis, and osteomyelitis. In recent years, treatment of these infections has become challenging owing to increased virulence of some organisms and drug resistance. Treatment involves a combination of proper antimicrobial therapy, immobilization, edema control, and adequate surgical therapy. Best practice management requires use of appropriate diagnostic tools, understanding by the surgeon of the unique and complex anatomy of the hand, and proper antibiotic selection in consultation with infectious disease specialists. (J Hand Surg 2011;36A:1403-1412. (C) 2011 Published by Elsevier Inc. on behalf of the American Society for Surgery of the Hand.) C1 USN, Div Infect Dis, Dept Internal Med, San Diego Med Ctr, San Diego, CA 92134 USA. USN, Div Hand & Microvasc Surg, Dept Orthoped Surg, San Diego Med Ctr, San Diego, CA 92134 USA. RP Kroonen, LT (reprint author), USN, Dept Orthopaed Surg, San Diego Med Ctr, 34800 Bob Wilson Dr,Suite 112, San Diego, CA 92134 USA. EM leo.kroonen@med.navy.mil NR 34 TC 14 Z9 14 U1 1 U2 3 PU W B SAUNDERS CO-ELSEVIER INC PI PHILADELPHIA PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA SN 0363-5023 J9 J HAND SURG-AM JI J. Hand Surg.-Am. Vol. PD AUG PY 2011 VL 36A IS 8 BP 1403 EP 1412 DI 10.1016/j.jhsa.2011.05.035 PG 10 WC Orthopedics; Surgery SC Orthopedics; Surgery GA 804QP UT WOS:000293669400028 PM 21816297 ER PT J AU Hospenthal, DR Murray, CK Andersen, RC Bell, RB Calhoun, JH Cancio, LC Cho, JM Chung, KK Clasper, JC Colyer, MH Conger, NG Costanzo, GP Crouch, HK Curry, TK D'Avignon, LC Dorlac, WC Dunne, JR Eastridge, BJ Ficke, JR Fleming, ME Forgione, MA Green, AD Hale, RG Hayes, DK Holcomb, JB Hsu, JR Kester, KE Martin, GJ Moores, LE Obremskey, WT Petersen, K Renz, EM Saffle, JR Solomkin, JS Sutter, DE Tribble, DR Wenke, JC Whitman, TJ Wiesen, AR Wortmann, GW AF Hospenthal, Duane R. Murray, Clinton K. Andersen, Romney C. Bell, R. Bryan Calhoun, Jason H. Cancio, Leopoldo C. Cho, John M. Chung, Kevin K. Clasper, Jon C. Colyer, Marcus H. Conger, Nicholas G. Costanzo, George P. Crouch, Helen K. Curry, Thomas K. D'Avignon, Laurie C. Dorlac, Warren C. Dunne, James R. Eastridge, Brian J. Ficke, James R. Fleming, Mark E. Forgione, Michael A. Green, Andrew D. Hale, Robert G. Hayes, David K. Holcomb, John B. Hsu, Joseph R. Kester, Kent E. Martin, Gregory J. Moores, Leon E. Obremskey, William T. Petersen, Kyle Renz, Evan M. Saffle, Jeffrey R. Solomkin, Joseph S. Sutter, Deena E. Tribble, David R. Wenke, Joseph C. Whitman, Timothy J. Wiesen, Andrew R. Wortmann, Glenn W. TI Executive Summary: Guidelines for the Prevention of Infections Associated With Combat-Related Injuries: 2011 Update Endorsed by the Infectious Diseases Society of America and the Surgical Infection Society SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Review DE Guidelines; Infection; Combat; Trauma; Prevention AB Despite advances in resuscitation and surgical management of combat wounds, infection remains a concerning and potentially preventable complication of combat-related injuries. Interventions currently used to prevent these infections have not been either clearly defined or subjected to rigorous clinical trials. Current infection prevention measures and wound management practices are derived from retrospective review of wartime experiences, from civilian trauma data, and from in vitro and animal data. This update to the guidelines published in 2008 incorporates evidence that has become available since 2007. These guidelines focus on care provided within hours to days of injury, chiefly within the combat zone, to those combat-injured patients with open wounds or burns. New in this update are a consolidation of antimicrobial agent recommendations to a backbone of high-dose cefazolin with or without metronidazole for most postinjury indications and recommendations for redosing of antimicrobial agents, for use of negative pressure wound therapy, and for oxygen supplementation in flight. C1 [Hospenthal, Duane R.] San Antonio Mil Med Ctr, Infect Dis Serv MCHE MDI, Ft Sam Houston, TX 78234 USA. [Cancio, Leopoldo C.; Chung, Kevin K.; Costanzo, George P.; Eastridge, Brian J.; Hale, Robert G.; Hsu, Joseph R.; Renz, Evan M.; Wenke, Joseph C.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Andersen, Romney C.; Colyer, Marcus H.; Dunne, James R.; Fleming, Mark E.; Martin, Gregory J.; Whitman, Timothy J.; Wortmann, Glenn W.] Walter Reed Natl Mil Med Ctr Bethesda, Bethesda, MD USA. [Tribble, David R.] Infect Dis Clin Res Program, Bethesda, MD USA. [Bell, R. Bryan] Oregon Hlth & Sci Univ, Portland, OR 97201 USA. [Calhoun, Jason H.] Ohio State Univ, Columbus, OH 43210 USA. [Cho, John M.] Landstuhl Reg Med Ctr, Landstuhl, Germany. [Clasper, Jon C.; Green, Andrew D.] Royal Ctr Def Med, Inst Res & Dev, Birmingham, W Midlands, England. [Conger, Nicholas G.; Forgione, Michael A.] Keesler Med Ctr, Keesler AFB, MS USA. [Curry, Thomas K.] Madigan Army Med Ctr, Ft Lewis, WA USA. [Wiesen, Andrew R.] Western Reg Med Command, Ft Lewis, WA USA. [D'Avignon, Laurie C.] USAF, Med Support Agcy, Lackland AFB, TX USA. [Dorlac, Warren C.; Solomkin, Joseph S.] Univ Cincinnati, Cincinnati, OH USA. [Holcomb, John B.] Univ Texas Hlth Sci Ctr, Houston, TX USA. [Kester, Kent E.] Walter Reed Army Inst Res, Silver Spring, MD USA. [Moores, Leon E.] Kimbrough Ambulatory Care Ctr, Ft George G Meade, MD USA. [Obremskey, William T.] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA. [Petersen, Kyle] USN, Med Res Ctr, Silver Spring, MD USA. [Saffle, Jeffrey R.] Univ Utah, Salt Lake City, UT USA. RP Hospenthal, DR (reprint author), San Antonio Mil Med Ctr, Infect Dis Serv MCHE MDI, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA. EM duane.hospenthal@us.army.mil FU US Army Medical Command FX Financial support for the consensus conference and publication of the Journal of Trauma supplement was provided by the US Army Medical Command. NR 6 TC 5 Z9 5 U1 0 U2 5 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0022-5282 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD AUG PY 2011 VL 71 SU 2 BP S202 EP S209 DI 10.1097/TA.0b013e318227ac37 PG 8 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 806XB UT WOS:000293849300002 PM 21814088 ER PT J AU Hospenthal, DR Murray, CK Andersen, RC Bell, RB Calhoun, JH Cancio, LC Cho, JM Chung, KK Clasper, JC Colyer, MH Conger, NG Costanzo, GP Crouch, HK Curry, TK D'Avignon, LC Dorlac, WC Dunne, JR Eastridge, BJ Ficke, JR Fleming, ME Forgione, MA Green, AD Hale, RG Hayes, DK Holcomb, JB Hsu, JR Kester, KE Martin, GJ Moores, LE Obremskey, WT Petersen, K Renz, EM Saffle, JR Solomkin, JS Sutter, DE Tribble, DR Wenke, JC Whitman, TJ Wiesen, AR Wortmann, GW AF Hospenthal, Duane R. Murray, Clinton K. Andersen, Romney C. Bell, R. Bryan Calhoun, Jason H. Cancio, Leopoldo C. Cho, John M. Chung, Kevin K. Clasper, Jon C. Colyer, Marcus H. Conger, Nicholas G. Costanzo, George P. Crouch, Helen K. Curry, Thomas K. D'Avignon, Laurie C. Dorlac, Warren C. Dunne, James R. Eastridge, Brian J. Ficke, James R. Fleming, Mark E. Forgione, Michael A. Green, Andrew D. Hale, Robert G. Hayes, David K. Holcomb, John B. Hsu, Joseph R. Kester, Kent E. Martin, Gregory J. Moores, Leon E. Obremskey, William T. Petersen, Kyle Renz, Evan M. Saffle, Jeffrey R. Solomkin, Joseph S. Sutter, Deena E. Tribble, David R. Wenke, Joseph C. Whitman, Timothy J. Wiesen, Andrew R. Wortmann, Glenn W. TI Guidelines for the Prevention of Infections Associated With Combat-Related Injuries: 2011 Update Endorsed by the Infectious Diseases Society of America and the Surgical Infection Society SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Review DE Guidelines; Infection; Combat; Trauma; Prevention ID OPERATION-IRAQI-FREEDOM; HYPERBARIC-OXYGEN THERAPY; SMALL-FRAGMENT WOUNDS; PENETRATING CRANIOCEREBRAL INJURIES; RANDOMIZED CLINICAL-TRIAL; INTRAOPERATIVE BLOOD-LOSS; VACUUM-ASSISTED CLOSURE; SEVERE OPEN FRACTURES; OPEN TIBIA FRACTURES; COMPLICATED INTRAABDOMINAL INFECTIONS AB Despite advances in resuscitation and surgical management of combat wounds, infection remains a concerning and potentially preventable complication of combat-related injuries. Interventions currently used to prevent these infections have not been either clearly defined or subjected to rigorous clinical trials. Current infection prevention measures and wound management practices are derived from retrospective review of wartime experiences, from civilian trauma data, and from in vitro and animal data. This update to the guidelines published in 2008 incorporates evidence that has become available since 2007. These guidelines focus on care provided within hours to days of injury, chiefly within the combat zone, to those combat-injured patients with open wounds or burns. New in this update are a consolidation of antimicrobial agent recommendations to a backbone of high-dose cefazolin with or without metronidazole for most postinjury indications, and recommendations for redosing of antimicrobial agents, for use of negative pressure wound therapy, and for oxygen supplementation in flight. C1 [Hospenthal, Duane R.] San Antonio Mil Med Ctr, Infect Dis Serv MCHE MDI, Ft Sam Houston, TX 78234 USA. [Cancio, Leopoldo C.; Chung, Kevin K.; Costanzo, George P.; Eastridge, Brian J.; Hale, Robert G.; Hsu, Joseph R.; Renz, Evan M.; Wenke, Joseph C.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Andersen, Romney C.; Colyer, Marcus H.; Dunne, James R.; Fleming, Mark E.; Martin, Gregory J.; Whitman, Timothy J.; Wortmann, Glenn W.] Walter Reed Natl Mil Med Ctr Bethesda, Bethesda, MD USA. [Tribble, David R.] Infect Dis Clin Res Program, Bethesda, MD USA. [Bell, R. Bryan] Oregon Hlth & Sci Univ, Portland, OR 97201 USA. [Calhoun, Jason H.] Ohio State Univ, Columbus, OH 43210 USA. [Cho, John M.] Landstuhl Reg Med Ctr, Landstuhl, Germany. [Clasper, Jon C.; Green, Andrew D.] Royal Ctr Def Med, Inst Res & Dev, Birmingham, W Midlands, England. [Conger, Nicholas G.; Forgione, Michael A.] Keesler Med Ctr, Keesler AFB, MS USA. [Curry, Thomas K.] Madigan Army Med Ctr, Ft Lewis, WA USA. [Wiesen, Andrew R.] Western Reg Med Command, Ft Lewis, WA USA. [D'Avignon, Laurie C.] USAF, Med Support Agcy, Lackland AFB, TX USA. [Dorlac, Warren C.; Solomkin, Joseph S.] Univ Cincinnati, Cincinnati, OH USA. [Holcomb, John B.] Univ Texas Hlth Sci Ctr, Houston, TX USA. [Kester, Kent E.] Walter Reed Army Inst Res, Silver Spring, MD USA. [Moores, Leon E.] Kimbrough Ambulatory Care Ctr, Ft George G Meade, MD USA. [Obremskey, William T.] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA. [Petersen, Kyle] USN, Med Res Ctr, Silver Spring, MD USA. [Saffle, Jeffrey R.] Univ Utah, Salt Lake City, UT USA. RP Hospenthal, DR (reprint author), San Antonio Mil Med Ctr, Infect Dis Serv MCHE MDI, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA. EM duane.hospenthal@us.army.mil FU US Army Medical Command FX Financial support for the consensus conference and publication of the Journal of Trauma supplement was provided by the US Army Medical Command. NR 291 TC 32 Z9 35 U1 1 U2 20 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0022-5282 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD AUG PY 2011 VL 71 SU 2 BP S210 EP S234 DI 10.1097/TA.0b013e318227ac4b PG 25 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 806XB UT WOS:000293849300003 PM 21814089 ER PT J AU Hospenthal, DR Green, AD Crouch, HK English, JF Pool, J Yun, HC Murray, CK AF Hospenthal, Duane R. Green, Andrew D. Crouch, Helen K. English, Judith F. Pool, Jane Yun, Heather C. Murray, Clinton K. CA Prevention Combat-Related Infect TI Infection Prevention and Control in Deployed Military Medical Treatment Facilities SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Review DE Infection control; Infection prevention; Combat; Trauma; Military ID MULTIDRUG-RESISTANT BACTERIA; US ARMY SOLDIERS; ACINETOBACTER-BAUMANNII; HEALTH-CARE; SKIN COLONIZATION; NATURAL-HISTORY; WAR WOUNDS; IRAQ; PERSONNEL; DEPAGE,ANTOINE AB Infections have complicated the care of combat casualties throughout history and were at one time considered part of the natural history of combat trauma. Personnel who survived to reach medical care were expected to develop and possibly succumb to infections during their care in military hospitals. Initial care of war wounds continues to focus on rapid surgical care with debridement and irrigation, aimed at preventing local infection and sepsis with bacteria from the environment (e.g., clostridial gangrene) or the casualty's own flora. Over the past 150 years, with the revelation that pathogens can be spread from patient to patient and from healthcare providers to patients (including via unwashed hands of healthcare workers, the hospital environment and fomites), a focus on infection prevention and control aimed at decreasing transmission of pathogens and prevention of these infections has developed. Infections associated with combat-related injuries in the recent operations in Iraq and Afghanistan have predominantly been secondary to multidrug-resistant pathogens, likely acquired within the military healthcare system. These healthcare-associated infections seem to originate throughout the system, from deployed medical treatment facilities through the chain of care outside of the combat zone. Emphasis on infection prevention and control, including hand hygiene, isolation, cohorting, and antibiotic control measures, in deployed medical treatment facilities is essential to reducing these healthcare-associated infections. This review was produced to support the Guidelines for the Prevention of Infections Associated With Combat-Related Injuries: 2011 Update contained in this supplement of Journal of Trauma. C1 [Hospenthal, Duane R.] San Antonio Mil Med Ctr, Infect Dis Serv MCHE MDI, Ft Sam Houston, TX 78234 USA. [Green, Andrew D.] Royal Ctr Def Med, Inst Res & Dev, Birmingham, W Midlands, England. [English, Judith F.] USN, Bur Med & Surg, Washington, DC USA. [Pool, Jane] Landstuhl Reg Med Ctr, Landstuhl, Germany. RP Hospenthal, DR (reprint author), San Antonio Mil Med Ctr, Infect Dis Serv MCHE MDI, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA. EM duane.hospenthal@us.army.mil FU US Army Medical Command FX Financial support for the consensus conference and publication of the Journal of Trauma supplement was provided by the US Army Medical Command. NR 53 TC 14 Z9 16 U1 0 U2 8 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0022-5282 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD AUG PY 2011 VL 71 SU 2 BP S290 EP S298 DI 10.1097/TA.0b013e318227add8 PG 9 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 806XB UT WOS:000293849300009 PM 21814095 ER PT J AU Petersen, K Colyer, MH Hayes, DK Hale, RG Bell, RB AF Petersen, Kyle Colyer, Marcus H. Hayes, David K. Hale, Robert G. Bell, R. Bryan CA Prevention Combat-Related Infect TI Prevention of Infections Associated With Combat-Related Eye, Maxillofacial, and Neck Injuries SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Review DE War; Trauma; Head; Face ID OPERATION-IRAQI-FREEDOM; RANDOMIZED CLINICAL-TRIAL; ANTIBIOTIC-PROPHYLAXIS; ENDURING FREEDOM; WAR INJURIES; BACTERIAL ENDOPHTHALMITIS; MANDIBULAR FRACTURES; PENETRATING INJURIES; FACIAL FRACTURES; DECISION-MAKING AB The percentage of combat wounds involving the eyes, maxillofacial, and neck regions reported in the literature is increasing, representing 36% of all combat-related injuries at the start of the Iraq War. Recent meta-analysis of 21st century eye, maxillofacial, and neck injuries described combat injury incidences of 8% to 20% for the face, 2% to 11% for the neck, and 0.5% to 13% for the eye and periocular structures. This article reviews recent data from military and civilian studies to support evidence-based recommendations for the prevention of infections associated with combat-related eye, maxillofacial, and neck injuries. The major emphasis of this review is on recent developments in surgical practice as new antimicrobial studies were not performed. Further studies of bacterial infection epidemiology and postinjury antimicrobial use in combat-related injuries to the eyes, maxillofacial, and neck region are needed to improve evidence-based medicine recommendations. This evidence-based medicine review was produced to support the Guidelines for the Prevention of Infections associated with Combat-related Injuries: 2011 Update contained in this supplement of Journal of Trauma. C1 [Petersen, Kyle] USN, Med Res Ctr, Silver Spring, MD USA. [Colyer, Marcus H.] Walter Reed Natl Mil Med Ctr Bethesda, Bethesda, MD USA. [Hayes, David K.] San Antonio Mil Med Ctr, Ft Sam Houston, TX USA. [Hale, Robert G.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Bell, R. Bryan] Oregon Hlth & Sci Univ, Portland, OR 97201 USA. RP Petersen, K (reprint author), USN, Med Res Ctr, 503 Robert Grant Ave, Bethesda, MD 20889 USA. EM kyle.petersen@med.navy.mil FU US Army Medical Command FX Financial support for the consensus conference and publication of the Journal of Trauma supplement was provided by the US Army Medical Command. NR 57 TC 6 Z9 8 U1 2 U2 4 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0022-5282 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD AUG PY 2011 VL 71 SU 2 BP S264 EP S269 DI 10.1097/TA.0b013e318227ad9a PG 6 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 806XB UT WOS:000293849300006 PM 21814092 ER PT J AU Santomauro, M Choe, C Heimbigner, J Roberts, J Auge, B AF Santomauro, Michael Choe, Chong Heimbigner, Jared Roberts, John Auge, Brian TI Castleman's Disease in the Left Suprarenal Region, Mimicking an Adrenal Neoplasm SO UROLOGY LA English DT Editorial Material ID TUMOR AB We present a rare case of a 16-year-old male patient with Castleman's disease (CD) manifest by a suspicious mass within the left suprarenal region abutting the left adrenal gland, mimicking an adrenal neoplasm. CD is an uncommon and poorly understood lymphoproliferative disorder that, when observed, typically occurs as a mediastinal mass. Two percent of cases reportedly occur in the pararenal region. Although rare, Castleman's disease should be considered in the differential diagnosis of a retroperitoneal mass. UROLOGY 78: 319, 2011. Published by Elsevier Inc. [GRAPHICS] . C1 [Santomauro, Michael; Choe, Chong; Heimbigner, Jared; Roberts, John; Auge, Brian] USN, Med Ctr, San Diego, CA 92134 USA. RP Santomauro, M (reprint author), USN, San Diego Med Ctr, Dept Urol, 34800 Bob Wilson Dr, San Diego, CA 92134 USA. EM michael.santomauro@med.navy.mil NR 4 TC 0 Z9 0 U1 0 U2 1 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 0090-4295 J9 UROLOGY JI Urology PD AUG PY 2011 VL 78 IS 2 BP 319 EP 319 DI 10.1016/j.urology.2010.12.031 PG 1 WC Urology & Nephrology SC Urology & Nephrology GA 803JH UT WOS:000293577100023 PM 21316092 ER PT J AU Ellis, AM Garcia, AJ Focks, DA Morrison, AC Scott, TW AF Ellis, Alicia M. Garcia, Andres J. Focks, Dana A. Morrison, Amy C. Scott, Thomas W. TI Parameterization and Sensitivity Analysis of a Complex Simulation Model for Mosquito Population Dynamics, Dengue Transmission, and Their Control SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID AEDES-AEGYPTI DIPTERA; MALARIA TRANSMISSION; DENSITY-DEPENDENCE; RELEASE-RECAPTURE; BITING ACTIVITY; HUMAN BLOOD; CULICIDAE; RISK; PATTERNS; SURVIVAL AB Models can be useful tools for understanding the dynamics and control of mosquito-borne disease. More detailed models may be more realistic and better suited for understanding local disease dynamics; however, evaluating model suitability, accuracy, and performance becomes increasingly difficult with greater model complexity. Sensitivity analysis is a technique that permits exploration of complex models by evaluating the sensitivity of the model to changes in parameters. Here, we present results of sensitivity analyses of two interrelated complex simulation models of mosquito population dynamics and dengue transmission. We found that dengue transmission may be influenced most by survival in each life stage of the mosquito, mosquito biting behavior, and duration of the infectious period in humans. The importance of these biological processes for vector-borne disease models and the overwhelming lack of knowledge about them make acquisition of relevant field data on these biological processes a top research priority. C1 [Ellis, Alicia M.; Morrison, Amy C.; Scott, Thomas W.] Univ Calif Davis, Dept Entomol, Davis, CA 95618 USA. [Ellis, Alicia M.; Scott, Thomas W.] NIH, Fogarty Int Ctr, Bethesda, MD 20892 USA. [Focks, Dana A.] Univ Florida, Emerging Pathogens Inst, Dept Environm & Global Hlth, Gainesville, FL USA. [Garcia, Andres J.] Univ Florida, Dept Geog, Emerging Pathogens Inst, Gainesville, FL 32611 USA. [Morrison, Amy C.] USN, Med Res Ctr Detachment, Washington, DC USA. RP Ellis, AM (reprint author), Univ Calif Davis, Dept Entomol, 1 Shields Ave, Davis, CA 95618 USA. EM alicia.m.ellis@gmail.com; andygarcia@gmail.com; DAFocks@id-analysis.com; amy.aegypti@gmail.com; twscott@caes.ucdavis.edu RI Barley, Kamal/F-9579-2011 OI Barley, Kamal/0000-0003-1874-9813 FU Innovative Vector Control Consortium; Department of Homeland Security, and Fogarty International Center, National Institutes of Health FX This research was supported by the Innovative Vector Control Consortium (http://www.ivcc.com/) and the Research and Policy for Infectious Disease Dynamics (RAPIDD) program of the Science and Technology Directory, Department of Homeland Security, and Fogarty International Center, National Institutes of Health. Initial support for the improvement of the dengue models came from the Jean and Julius Tahija Family Foundation, Jakarta, Indonesia. Many thanks to Dr. Steven Stoddard for help in obtaining and interpreting epidemiological and entomological data from the Iquitos surveys, Bborie Park (University of California Davis) for help with computer setup and data organization, and Dr. Chonggang Xu for valuable input on sensitivity analysis procedures. NR 48 TC 20 Z9 20 U1 2 U2 14 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD AUG PY 2011 VL 85 IS 2 BP 257 EP 264 DI 10.4269/ajtmh.2011.10-0516 PG 8 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA 803WN UT WOS:000293613000013 PM 21813844 ER PT J AU Buryk, M Bloom, D Shope, T AF Buryk, Melissa Bloom, David Shope, Timothy TI Efficacy of Neonatal Release of Ankyloglossia: A Randomized Trial SO PEDIATRICS LA English DT Article DE ankyloglossia; frenotomy; breastfeeding; Hazelbaker; tongue-tie ID MCGILL-PAIN-QUESTIONNAIRE; TONGUE-TIE; FEEDING DIFFICULTIES; HUMAN-MILK; INFANTS; DIVISION AB BACKGROUND: Ankyloglossia has been associated with a variety of infant-feeding problems. Frenotomy commonly is performed for relief of ankyloglossia, but there has been a lack of convincing data to support this practice. OBJECTIVES: Our primary objective was to determine whether frenotomy for infants with ankyloglossia improved maternal nipple pain and ability to breastfeed. A secondary objective was to determine whether frenotomy improved the length of breastfeeding. METHODS: Over a 12-month period, neonates who had difficulty breastfeeding and significant ankyloglossia were enrolled in this randomized, single-blinded, controlled trial and assigned to either a frenotomy (30 infants) or a sham procedure (28 infants). Breastfeeding was assessed by a preintervention and postintervention nipple-pain scale and the Infant Breastfeeding Assessment Tool. The same tools were used at the 2-week follow-up and regularly scheduled follow-ups over a 1-year period. The infants in the sham group were given a frenotomy before or at the 2-week follow-up if it was desired. RESULTS: Both groups demonstrated statistically significantly decreased pain scores after the intervention. The frenotomy group improved significantly more than the sham group (P < .001). Breastfeeding scores significantly improved in the frenotomy group (P = .029) without a significant change in the control group. All but 1 parent in the sham group elected to have the procedure performed when their infant reached 2 weeks of age, which prevented additional comparisons between the 2 groups. CONCLUSIONS: We demonstrated immediate improvement in nipple-pain and breastfeeding scores, despite a placebo effect on nipple pain. This should provide convincing evidence for those seeking a frenotomy for infants with signficant ankyloglossia. Pediatrics 2011;128:280-288 C1 [Buryk, Melissa; Bloom, David; Shope, Timothy] USN, Med Ctr Portsmouth, Portsmouth, VA 23708 USA. RP Buryk, M (reprint author), USN, Med Ctr Portsmouth, 620 John Paul Jones Cir, Portsmouth, VA 23708 USA. EM melissa.buryk@gmail.com NR 28 TC 42 Z9 49 U1 1 U2 17 PU AMER ACAD PEDIATRICS PI ELK GROVE VILLAGE PA 141 NORTH-WEST POINT BLVD,, ELK GROVE VILLAGE, IL 60007-1098 USA SN 0031-4005 J9 PEDIATRICS JI Pediatrics PD AUG PY 2011 VL 128 IS 2 BP 280 EP 288 DI 10.1542/peds.2011-0077 PG 9 WC Pediatrics SC Pediatrics GA 800CK UT WOS:000293336200042 PM 21768318 ER PT J AU Schoenfeld, AJ McCriskin, B Hsiao, M Burks, R AF Schoenfeld, A. J. McCriskin, B. Hsiao, M. Burks, R. TI Incidence and epidemiology of spinal cord injury within a closed American population: the United States military (2000-2009) SO SPINAL CORD LA English DT Article DE spinal cord injury; incidence; epidemiology ID CANADA; RISK AB Study design: Cohort study Objectives: The objective of this study was to characterize the incidence of spinal cord injury (SCI) within the population of the United States military from 2000-2009. This investigation also sought to define potential risk factors for the development of SCI. Setting: The population of the United States military from 2000-2009. Methods: The Defense Medical Epidemiology Database was queried for the years 2000-2009 using the International Classification of Diseases, Ninth Revision, Clinical Modification codes for SCI (806.0, 806.1, 806.2, 806.3, 806.4, 806.5, 806.8, 806.9, 952.0, 952.1, 952.2, 952.8, 952.9). The raw incidence of SCI was calculated and unadjusted incidence rates were generated for the risk factors of age, sex, race, military rank and branch of service. Adjusted incidence rate ratios were subsequently determined via multivariate Poisson regression analysis that controlled for other factors in the model and identified significant independent risk factors for SCI. Results: Between 2000 and 2009, there were 5928 cases of SCI among a population at-risk of 13 813 333. The raw incidence of SCI within the population was 429 per million person-years. Male sex, white race, enlisted personnel and service in the Army, Navy or Marine Corps were found to be significant independent risk factors for SCI. The age groups 20-24, 25-29 and 440 were also found to be at significantly greater risk of developing the condition. Conclusions: This study is one of the few investigations to characterize the incidence, epidemiology and risk factors for SCI within the United States. Results presented here may represent the best-available evidence for risk factors of SCI in a large and diverse American cohort. Spinal Cord (2011) 49, 874-879; doi:10.1038/sc.2011.18; published online 8 March 2011 C1 [Schoenfeld, A. J.; McCriskin, B.] Texas Tech Univ Hlth Sci Ctr, William Beaumont Army Med Ctr, Dept Orthopaed Surg, El Paso, TX 79920 USA. [Hsiao, M.] Creighton Univ, Sch Med, Omaha, NE USA. [Burks, R.] USN, Postgrad Sch, Monterrey, CA USA. RP Schoenfeld, AJ (reprint author), Texas Tech Univ Hlth Sci Ctr, William Beaumont Army Med Ctr, Dept Orthopaed Surg, 5005 N Piedras St, El Paso, TX 79920 USA. EM ajschoen@neoucom.edu RI Burks, Robert/J-2481-2015; OI Burks, Robert/0000-0001-6443-6653; Schoenfeld, Andrew/0000-0002-3691-1215 NR 20 TC 12 Z9 13 U1 0 U2 3 PU NATURE PUBLISHING GROUP PI LONDON PA MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND SN 1362-4393 J9 SPINAL CORD JI Spinal Cord PD AUG PY 2011 VL 49 IS 8 BP 874 EP 879 DI 10.1038/sc.2011.18 PG 6 WC Clinical Neurology; Rehabilitation SC Neurosciences & Neurology; Rehabilitation GA 803HS UT WOS:000293573000004 PM 21383763 ER PT J AU Nakhla, I El Mohammady, H Mansour, A Klena, JD Hassan, K Sultan, Y Pastoor, R Abdoel, TH Smits, H AF Nakhla, Isabelle El Mohammady, Hanan Mansour, Adel Klena, John D. Hassan, Khaled Sultan, Yehia Pastoor, Rob Abdoel, Theresia H. Smits, Henk TI Validation of the Dri-Dot Latex agglutination and IgM lateral flow assays for the diagnosis of typhoid fever in an Egyptian population SO DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE LA English DT Article DE Typhoid fever; Rapid diagnostics; Latex agglutination; Lateral flow ID SALMONELLA-TYPHI; BONE-MARROW; DIPSTICK ASSAY; ENTERIC FEVER; WIDAL TEST; ANTIBODIES; BLOOD; SERODIAGNOSIS; CULTURES; TRENDS AB Laboratory confirmation of typhoid fever is essential for appropriate medical treatment. Blood culture is a standard test for diagnosis of typhoid fever, but well-equipped diagnostic facilities to perform culture are seldom available in endemic areas. We retrospectively compared 2 diagnostic field tests, a latex agglutination Dri-Dot assay and an IgM Lateral Flow assay, to blood culture, in patients with clinically diagnosed typhoid fever. Sensitivity of the Dri-Dot was 71.4%, and specificity was 86.3% for samples collected at time of first diagnosis. Sensitivity and specificity of IgM Lateral Flow were 80% and 71.4%, respectively. A major limitation of these serologic tests is the limited sensitivity at the early stage of the disease. Performing both tests in parallel increased sensitivity to 84.3%, but decreased specificity to 70.5%. There was a trend towards improved diagnostic performance using either assay over a longer duration of illness. These rapid, point-of-care assays for typhoid fever provide easy-to-interpret results in typhoid-endemic countries and may be most useful in patients presenting 1 week after symptom onset. Published by Elsevier Inc. C1 [Nakhla, Isabelle; El Mohammady, Hanan; Mansour, Adel; Klena, John D.; Hassan, Khaled] USN, Med Res Unit 3, FPO, AE 09835 USA. [Sultan, Yehia] Abbassia Fever Hosp, Cairo 11517, Egypt. [Pastoor, Rob; Abdoel, Theresia H.; Smits, Henk] KIT, Royal Trop Inst, KIT Biomed Res, NL-1105 AZ Amsterdam, Netherlands. RP Nakhla, I (reprint author), USN, Med Res Unit 3, FPO, AE 09835 USA. EM isabelle.nakhla.eg@med.navy.mil RI Valle, Ruben/A-7512-2013 NR 33 TC 4 Z9 4 U1 2 U2 8 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 0732-8893 J9 DIAGN MICR INFEC DIS JI Diagn. Microbiol. Infect. Dis. PD AUG PY 2011 VL 70 IS 4 BP 435 EP 441 DI 10.1016/j.diagmicrobio.2011.03.020 PG 7 WC Infectious Diseases; Microbiology SC Infectious Diseases; Microbiology GA 799WN UT WOS:000293316900002 PM 21658878 ER PT J AU Beverly, R Garfinkel, S Cardwell, G AF Beverly, Robert Garfinkel, Simson Cardwell, Greg TI Forensic carving of network packets and associated data structures SO DIGITAL INVESTIGATION LA English DT Article; Proceedings Paper CT 11th Annual DFRWS Conference CY AUG 01-03, 2011 CL New Orleans, LA DE Carving; Network Carving; bulk_extractor; Network analysis; Cross drive analysis ID SYSTEM AB Using validated carving techniques, we show that popular operating systems (e.g. Windows, Linux, and OSX) frequently have residual IP packets, Ethernet frames, and associated data structures present in system memory from long-terminated network traffic. Such information is useful for many forensic purposes including establishment of prior connection activity and services used; identification of other systems present on the system's LAN or WLAN; geolocation of the host computer system; and cross-drive analysis. We show that network structures can also be recovered from memory that is persisted onto a mass storage medium during the course of system swapping or hibernation. We present our network carving techniques, algorithms and tools, and validate these against both purpose-built memory images and a readily available forensic corpora. These techniques are valuable to both forensics tasks, particularly in analyzing mobile devices, and to cyber-security objectives such as malware analysis. Published by Elsevier Ltd. C1 [Beverly, Robert; Garfinkel, Simson; Cardwell, Greg] USN, Postgrad Sch, Monterey, CA USA. RP Garfinkel, S (reprint author), USN, Postgrad Sch, Monterey, CA USA. EM rbeverly@nps.edu; slgarfin@nps.edu NR 26 TC 6 Z9 6 U1 0 U2 5 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 1742-2876 J9 DIGIT INVEST JI Digit. Investig. PD AUG PY 2011 VL 8 SU 1 BP S78 EP S89 DI 10.1016/j.diin.2011.05.010 PG 12 WC Computer Science, Information Systems; Computer Science, Interdisciplinary Applications SC Computer Science GA 799GL UT WOS:000293273800010 ER PT J AU Farnsworth, J Amitay, M Beal, D Huyer, SA AF Farnsworth, John Amitay, Michael Beal, David Huyer, Stephen A. TI Measurements of a stator-induced circumferentially varying flow SO EXPERIMENTS IN FLUIDS LA English DT Article ID PARTICLE IMAGE VELOCIMETRY; PROPELLERS AB The flow physics associated with the generation of both axisymmetric and non-axisymmetric swirl by various deflection patterns of a stator array was investigated experimentally through surface pressure and Stereoscopic Particle Image Velocimetry measurements. A three-dimensional rendering technique was developed to reconstruct the flow field around the model and in its wake. The three-dimensional fluid volume was reconstructed from multiple two-dimensional measurement planes. A cyclic distribution of the stators' deflections resulted in non-axisymmetric distributions of the surface pressure and the flow field downstream of the stator array. The addition of a shroud had an amplifying effect: accelerating the flow through the stator array while reducing the non-uniform tangential velocity component generated by the stators. In the model near wake the flow field is associated with secondary flow patterns in the form of coherent streamwise vortical structures that can be described by potential flow mechanisms. The collective pitch distribution of the stators produces a flow field that resembles a potential Rankine vortex, whereas the cyclic pitch distribution generates a flow pattern that can be described by a potential vortex pair in a cross-flow. C1 [Farnsworth, John; Amitay, Michael] Rensselaer Polytech Inst, Troy, NY 12180 USA. [Beal, David; Huyer, Stephen A.] USN, Undersea Warfare Ctr Div Newport, Newport, RI 02841 USA. RP Amitay, M (reprint author), Rensselaer Polytech Inst, 110 8th St, Troy, NY 12180 USA. EM amitam@rpi.edu FU Office of Naval Research through the University Lab Initiative [N000140810130] FX This project was funded by the Office of Naval Research through the University Lab Initiative Program (Award No.: N000140810130, monitored by Mrs. Maria Medeiros and Dr. Scott Hassan). NR 11 TC 4 Z9 4 U1 1 U2 10 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 0723-4864 J9 EXP FLUIDS JI Exp. Fluids PD AUG PY 2011 VL 51 IS 2 BP 423 EP 442 DI 10.1007/s00348-011-1060-z PG 20 WC Engineering, Mechanical; Mechanics SC Engineering; Mechanics GA 797NZ UT WOS:000293135900009 ER PT J AU Carroll, TL Rachford, FJ AF Carroll, T. L. Rachford, F. J. TI Non-linear dynamics method for target identification SO IET RADAR SONAR AND NAVIGATION LA English DT Article ID DIMENSION; SYSTEMS; RADAR; FILTERS; SIGNALS AB One may describe the effect of a radar or sonar target on an incoming signal as a filter that produces a scattered signal. Chaotic signals are very sensitive to the effect of filters, and so a radar or sonar target imposes a unique signature on a scattered chaotic signal. In this study the authors describe a method that uses the concept of phase space dimension to create a reference from a scattered chaotic signal. This reference becomes part of a library, and comparing an unknown scattered signal to this library can reveal which target caused a particular scattered signal. As the authors are not imaging the target, this method can use signal with low-range resolution. C1 [Carroll, T. L.; Rachford, F. J.] USN, Res Lab, Washington, DC 20375 USA. RP Carroll, TL (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM thomas.carroll@nrl.navy.mil OI Carroll, Thomas/0000-0002-2371-2049 NR 27 TC 3 Z9 3 U1 0 U2 2 PU INST ENGINEERING TECHNOLOGY-IET PI HERTFORD PA MICHAEL FARADAY HOUSE SIX HILLS WAY STEVENAGE, HERTFORD SG1 2AY, ENGLAND SN 1751-8784 J9 IET RADAR SONAR NAV JI IET Radar Sonar Navig. PD AUG PY 2011 VL 5 IS 7 BP 741 EP 746 DI 10.1049/iet-rsn.2010.0381 PG 6 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA 797MC UT WOS:000293131000006 ER PT J AU Larson, MA Fey, PD Bartling, AM Iwen, PC Dempsey, MP Francesconi, SC Hinrichs, SH AF Larson, Marilynn A. Fey, Paul D. Bartling, Amanda M. Iwen, Peter C. Dempsey, Michael P. Francesconi, Stephen C. Hinrichs, Steven H. TI Francisella tularensis Molecular Typing Using Differential Insertion Sequence Amplification SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article ID SUBSP TULARENSIS; POPULATION-STRUCTURE; DERMACENTOR TICKS; GENOME SEQUENCE; UNITED-STATES; ENDOSYMBIONTS; HOLARCTICA; DISCRIMINATION; PHYLOGEOGRAPHY; REARRANGEMENT AB Tularemia is a potentially fatal disease that is caused by the highly infectious and zoonotic pathogen Francisella tularensis. Despite the monomorphic nature of sequenced F. tularensis genomes, there is a significant degree of plasticity in the organization of genetic elements. The observed variability in these genomes is due primarily to the transposition of direct repeats and insertion sequence (IS) elements. Since current methods used to genotype F. tularensis are time-consuming and require extensive laboratory resources, IS elements were investigated as a means to subtype this organism. The unique spatial location of specific IS elements provided the basis for the development of a differential IS amplification (DISA) assay to detect and distinguish the more virulent F. tularensis subsp. tularensis (subtypes A. I and A.II) and subsp. holarctica (type B) strains from F. tularensis subsp. novicida and other near neighbors, including Francisella philomiragia and Francisella-like endosymbionts found in ticks. Amplicon sizes and sequences derived from DISA showed heterogeneity within members of the subtype A. I and A.II isolates but not the type B strains. These differences were due to a 312-bp fragment derived from the IS element ISFtu1. Analysis of wild-type F. tularensis isolates by DISA correlated with pulsed-field gel electrophoresis genotyping utilizing two different restriction endonucleases and provided rapid results with minimal sample processing. The applicability of this molecular typing assay for environmental studies was demonstrated by the accurate identification and differentiation of tick-borne F. tularensis. The described approach to IS targeting and amplification provides new capability for epidemiological investigations and characterizations of tularemia source outbreaks. C1 [Larson, Marilynn A.; Fey, Paul D.; Bartling, Amanda M.; Iwen, Peter C.; Hinrichs, Steven H.] Univ Nebraska Med Ctr, Dept Pathol & Microbiol, Omaha, NE 68198 USA. [Dempsey, Michael P.] Armed Forces Inst Pathol, Div Microbiol, Washington, DC 20306 USA. [Francesconi, Stephen C.] USN, Med Res Ctr, Silver Spring, MD USA. RP Larson, MA (reprint author), Univ Nebraska Med Ctr, Dept Pathol & Microbiol, 985900 Nebraska Med Ctr, Omaha, NE 68198 USA. EM malarson@unmc.edu OI Larson, Marilynn/0000-0002-0633-0313 FU U.S. Army Space and Missile Defense Command, Frederick, MD [W9113M-07-1-0004] FX The U.S. Army Space and Missile Defense Command, Frederick, MD, is the awarding and administering acquisition office that supported this work with a grant (W9113M-07-1-0004) to the University of Nebraska Medical Center (S. H. H.). NR 35 TC 4 Z9 5 U1 0 U2 2 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD AUG PY 2011 VL 49 IS 8 BP 2786 EP 2797 DI 10.1128/JCM.00033-11 PG 12 WC Microbiology SC Microbiology GA 798PE UT WOS:000293221900002 PM 21613430 ER PT J AU Chu, PC AF Chu, Peter C. TI Global upper ocean heat content and climate variability SO OCEAN DYNAMICS LA English DT Article DE Dipole Mode Index (DMI); El Nino; Pseudo-El Nino; Global Temperature and Salinity Profile Program (GTSPP); Indian Ocean Dipole; Monthly varying global (T, S) field; Optimal spectral decomposition (OSD); Southern Oscillation Index (SOI); Upper ocean heat content ID TROPICAL INDIAN-OCEAN; FLOW DECOMPOSITION; DIPOLE; SPARSE AB Observational data from the Global Temperature and Salinity Profile Program were used to calculate the upper ocean heat content (OHC) anomaly. The thickness of the upper layer is taken as 300 m for the Pacific/Atlantic Ocean and 150 m for the Indian Ocean since the Indian Ocean has shallower thermoclines. First, the optimal spectral decomposition scheme was used to build up monthly synoptic temperature and salinity dataset for January 1990 to December 2009 on 1 degrees x1 degrees grids and the same 33 vertical levels as the World Ocean Atlas. Then, the monthly varying upper layer OHC field (H) was obtained. Second, a composite analysis was conducted to obtain the total-time mean OHC field (H) and the monthly mean OHC variability ((H) over tilde), which is found an order of magnitude smaller than (H) over tilde. Third, an empirical orthogonal function (EOF) method is conducted on the residue data ((H) over tilde), deviating from (H) over tilde+(H) over tilde, in order to obtain interannual variations of the OHC fields for the three oceans. In the Pacific Ocean, the first two EOF modes account for 51.46% and 13.71% of the variance, representing canonical El Nino/La Nina (EOF-1) and pseudo-El Nino/La Nina (i.e., El Nino Modoki; EOF-2) events. In the Indian Ocean, the first two EOF modes account for 24.27% and 20.94% of the variance, representing basin-scale cooling/warming (EOF-1) and Indian Ocean Dipole (EOF-2) events. In the Atlantic Ocean, the first EOF mode accounts for 49.26% of the variance, representing a basin-scale cooling/warming (EOF-1) event. The second EOF mode accounts for 8.83% of the variance. Different from the Pacific and Indian Oceans, there is no zonal dipole mode in the tropical Atlantic Ocean. Fourth, evident lag correlation coefficients are found between the first principal component of the Pacific Ocean and the Southern Oscillation Index with a maximum correlation coefficient (0.68) at 1-month lead of the EOF-1 and between the second principal component of the Indian Ocean and the Dipole Mode Index with maximum values (around 0.53) at 1-2-month advance of the EOF-2. It implies that OHC anomaly contains climate variability signals. C1 USN, Postgrad Sch, Dept Oceanog, Monterey, CA 93943 USA. RP Chu, PC (reprint author), USN, Postgrad Sch, Dept Oceanog, Monterey, CA 93943 USA. EM pcchu@nps.edu FU Office of Naval Research; Naval Oceanographic Office; Naval Postgraduate School FX Office of Naval Research, the Naval Oceanographic Office, and the Naval Postgraduate School supported this study. The author thanks Dr. Noden E. Huang at the National Central University in Taiwan for stimulating discussion, Dr. L. Charles Sun at NOAA/NODC for providing the GTSPP data, and Mr. Chenwu Fan at NPS for computing assistance. NR 16 TC 7 Z9 8 U1 0 U2 4 PU SPRINGER HEIDELBERG PI HEIDELBERG PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY SN 1616-7341 J9 OCEAN DYNAM JI Ocean Dyn. PD AUG PY 2011 VL 61 IS 8 BP 1189 EP 1204 DI 10.1007/s10236-011-0411-x PG 16 WC Oceanography SC Oceanography GA 797QD UT WOS:000293141500008 ER PT J AU Cress, CD Polly, SJ Hubbard, SM Raffaelle, RP Walters, RJ AF Cress, Cory D. Polly, Stephen J. Hubbard, Seth M. Raffaelle, Ryne P. Walters, Robert J. TI Demonstration of a nipi-diode photovoltaic SO PROGRESS IN PHOTOVOLTAICS LA English DT Article DE nipi diode; solar cell modeling; quantum dot solar cell; quantum well solar cell; band structure engineering; ohmic contact; etching GaAs ID DOPING SUPERLATTICES; CRYSTALS; SUPERSTRUCTURE; ELECTRON AB The simulation, growth, processing, and characterization of a three-period GaAs n-type/intrinsic/p-type/intrinsic ... (nipi) doping solar cell is demonstrated. A V-groove etching process is characterized and used to expose the multiple n-type and p-type layers for electrical connection made by interdigitated grid-finger electrodes. A five-layer photolithographic process flow is developed and used to make 1 x 1 cm(2) devices with varying grid-finger separation. Device simulations of the structure indicate that strong rectification can be achieved in the parallel-connected three period nipi GaAs solar cell structure provided the necessary semiconductor doping compensation is achieved in the region near the metal-semiconductor interfaces. Experimentally, the improvements observed in the open circuit voltage, short circuit current, and ideality of the devices following thermal annealing suggests the formation of barriers near the contacts, which support the simulation results. A comparison of the short circuit current and series resistance under illumination indicate a tradeoff between shadowing and series resistance, which may be overcome with modification to the device structure. Ultimately, these results show promise towards the development of high efficiency solar cells or radioisotope batteries, and offer a novel device structure for the incorporation of nano-structures such as quantum wells or quantum dots. Copyright (C) 2011 John Wiley & Sons, Ltd. C1 [Cress, Cory D.; Walters, Robert J.] USN, Div Elect Sci & Technol, Res Lab, Washington, DC 20375 USA. [Cress, Cory D.; Polly, Stephen J.; Hubbard, Seth M.; Raffaelle, Ryne P.] Rochester Inst Technol, NanoPower Res Lab, Rochester, NY 14623 USA. [Raffaelle, Ryne P.] Natl Renewable Energy Lab, Natl Ctr Photovolta, Golden, CO 80401 USA. RP Cress, CD (reprint author), USN, Div Elect Sci & Technol, Res Lab, Washington, DC 20375 USA. EM nanoPV@nrl.navy.mil RI Polly, Stephen/C-1776-2015; OI Polly, Stephen/0000-0002-7563-6738; Cress, Cory/0000-0001-7563-6693 NR 19 TC 8 Z9 8 U1 1 U2 14 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1062-7995 J9 PROG PHOTOVOLTAICS JI Prog. Photovoltaics PD AUG PY 2011 VL 19 IS 5 BP 552 EP 559 DI 10.1002/pip.1071 PG 8 WC Energy & Fuels; Materials Science, Multidisciplinary; Physics, Applied SC Energy & Fuels; Materials Science; Physics GA 799GK UT WOS:000293273700007 ER PT J AU Hartkopf, WI Mason, BD AF Hartkopf, William I. Mason, Brian D. TI SPECKLE INTERFEROMETRY AT THE USNO FLAGSTAFF STATION: OBSERVATIONS OBTAINED IN 2008 AND NINE NEW ORBITS SO ASTRONOMICAL JOURNAL LA English DT Article DE binaries: general; binaries: visual; techniques: interferometric ID VISUAL BINARY STARS; ASTROMETRIC MEASUREMENTS; ELEMENTS; HIPPARCOS; SYSTEMS; MERATE; PISCO AB Results are presented for 299 speckle interferometric observations of double stars, obtained in 2008 at the USNO Flagstaff Station using the 1.55 m Kaj Strand Astrometric Reflector. Separations range from 0 ''.15 to 9 ''.88, with a median of 2 ''.22. This observing run concentrated on neglected systems, as well as systems in need of improved orbital elements; new orbital solutions have been determined for nine systems as a result. C1 [Hartkopf, William I.; Mason, Brian D.] USN Observ, Washington, DC 20392 USA. RP Hartkopf, WI (reprint author), USN Observ, 3450 Massachusetts Ave NW, Washington, DC 20392 USA. EM wih@usno.navy.mil; bdm@usno.navy.mil NR 43 TC 8 Z9 8 U1 0 U2 3 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-6256 J9 ASTRON J JI Astron. J. PD AUG PY 2011 VL 142 IS 2 AR 56 DI 10.1088/0004-6256/142/2/56 PG 10 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 794IH UT WOS:000292888200023 ER PT J AU Mason, BD Hartkopf, WI Wycoff, GL AF Mason, Brian D. Hartkopf, William I. Wycoff, Gary L. TI SPECKLE INTERFEROMETRY AT THE US NAVAL OBSERVATORY. XVII. SO ASTRONOMICAL JOURNAL LA English DT Article DE binaries: general; binaries: visual ID PROPER-MOTION STARS; VISUAL BINARIES; PHOTOGRAPHIC ASTROMETRY; ORBITAL ELEMENTS; SYSTEMS; AB AB The results of 3362 intensified CCD observations of double stars, made with the 26 inch refractor of the U.S. Naval Observatory, are presented. Each observation of a system represents a combination of over 2000 short-exposure images. These observations are averaged into 1970 mean relative positions and range in separation from 0 ''.78 to 72 ''.17, with amean separation of 14 ''.76. This is the 17th in this series of papers and covers the period 2010 January 6 through December 20. Also presented are 10 pairs that are resolved for the first time. C1 [Mason, Brian D.; Hartkopf, William I.; Wycoff, Gary L.] USN Observ, Washington, DC 20392 USA. RP Mason, BD (reprint author), USN Observ, 3450 Massachusetts Ave NW, Washington, DC 20392 USA. EM bdm@usno.navy.mil; wih@usno.navy.mil NR 64 TC 3 Z9 3 U1 0 U2 3 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-6256 J9 ASTRON J JI Astron. J. PD AUG PY 2011 VL 142 IS 2 AR 46 DI 10.1088/0004-6256/142/2/46 PG 4 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 794IH UT WOS:000292888200013 ER PT J AU Brown, VA Brooke, A Fordyce, JA McCracken, GF AF Brown, Veronica A. Brooke, Anne Fordyce, James A. McCracken, Gary F. TI Genetic analysis of populations of the threatened bat Pteropus mariannus SO CONSERVATION GENETICS LA English DT Article DE Pteropus marianus; Flying fox; Phylogeny; Mariana Islands; Palau ID CONSERVATION; PTEROPODIDAE; ISLANDS; MEGACHIROPTERA; MANAGEMENT; INFERENCE; UNITS AB The Mariana flying fox (Pteropus mariannus) has suffered substantial decline in recent years. Taxonomic classification of P. mariannus has been inconsistent, with subspecies designations based mainly on geography and morphological variation within small sample sizes. In this study, we examine relationships of P. mariannus across two island groups in the western Pacific Ocean. Microsatellite data and mitochondrial sequences, from D-loop, cytochrome oxidase I, and cytochrome b, suggest that the population on the islands of Palau is genetically isolated from the populations in the Mariana Islands. Our data confirm that the bats of Palau should be considered a separate conservation unit from the bats of the Mariana Islands, supporting the current subspecies separation of these two populations. Our results also suggest that there is gene flow among islands within the Mariana archipelago and that the bats on these islands, currently classified as two subspecies, should be managed as a single conservation unit, although we refrain from suggesting taxonomic revisions until genetic and morphological data become available from geographically intermediate populations. C1 [Brown, Veronica A.; Fordyce, James A.; McCracken, Gary F.] Univ Tennessee, Dept Ecol & Evolutionary Biol, Knoxville, TN 37996 USA. [Brooke, Anne] USN, NAVFAC Marianas, FPO AP, Santa Rita, GU 96915 USA. RP Brown, VA (reprint author), Univ Tennessee, Dept Ecol & Evolutionary Biol, 569 Dabney Hall,1416 Circle Dr, Knoxville, TN 37996 USA. EM vabrown@utk.edu OI McCracken, Gary/0000-0002-2493-8103 FU Lubee Bat Conservancy FX Dusty Janeke and Gary Wiles provided tissue samples used in this project. Gary Wiles also provided data on the morphological differences between bats in the Marianas and Palau and reviewed the manuscript. Lara Souza and two anonymous reviewers provided helpful comments on the manuscript. Ben Fitzpatrick, Amy Russell, and Steve Furches provided technical support. The Lubee Bat Conservancy provided funding for microsatellite development. The staff of the Recent Advances in Conservation Genetics Course provided insightful discussions of this data set and the analysis, especially Stephen O'Brien, Bailey Kessing, Warren Johnson, Jim Wilgenbusch, and Klaus Koepfli. NR 39 TC 8 Z9 9 U1 3 U2 32 PU SPRINGER PI DORDRECHT PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS SN 1566-0621 J9 CONSERV GENET JI Conserv. Genet. PD AUG PY 2011 VL 12 IS 4 BP 933 EP 941 DI 10.1007/s10592-011-0196-y PG 9 WC Biodiversity Conservation; Genetics & Heredity SC Biodiversity & Conservation; Genetics & Heredity GA 794FL UT WOS:000292880800006 ER PT J AU Schneidewind, N AF Schneidewind, Norman TI What can software engineers learn from manufacturing to improve software process and product? SO JOURNAL OF INTELLIGENT MANUFACTURING LA English DT Article DE Manufacturing methods; Software process; Software product; Product and process quality; Taguchi methods AB The purpose of this paper is to provide the software engineer with tools from the field of manufacturing as an aid to improving software process and product quality. Process involves classical manufacturing methods, such as statistical quality control applied to product testing, which is designed to monitor and correct the process when the process yields product quality that fails to meet specifications. Product quality is measured by metrics, such as failure count occurring on software during testing. When the process and product quality are out of control, we show what remedial action to take to bring both the process and product under control. NASA Space Shuttle failure data are used to illustrate the process methods. C1 USN, Postgrad Sch, Dept Informat Sci, Monterey, CA USA. RP Schneidewind, N (reprint author), USN, Postgrad Sch, Dept Informat Sci, Monterey, CA USA. EM ieeelife@yahoo.com NR 17 TC 1 Z9 1 U1 1 U2 3 PU SPRINGER PI DORDRECHT PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS SN 0956-5515 EI 1572-8145 J9 J INTELL MANUF JI J. Intell. Manuf. PD AUG PY 2011 VL 22 IS 4 BP 597 EP 606 DI 10.1007/s10845-009-0322-6 PG 10 WC Computer Science, Artificial Intelligence; Engineering, Manufacturing SC Computer Science; Engineering GA 794IQ UT WOS:000292889300011 ER PT J AU Beard, RL AF Beard, Ronald L. TI Role of the ITU-R in time scale definition and dissemination SO METROLOGIA LA English DT Article ID 2ND AB The International Telecommunications Union (ITU) is the leading United Nations agency for Radio and Telecommunications coordination worldwide. The process of managing overall frequency spectrum utilization is through Worldwide Radio Conferences, associated radiocommunication conferences and the activities of the Radiocommunication Study Groups. These Study Groups and their Working Parties, devoted to specialized technical areas, provide the mechanism for Member Nations to participate, study and recommend standards and practices to ensure equitable utilization and interference-free operation within the radio spectrum. An important underlying aspect of spectrum utilization is the facilitation of the determination and coordination of the international time scale. The international time scale is an atomic time scale used by broadcast services throughout the world known as Coordinated Universal Time (UTC). UTC is defined by the International Telecommunication Union (ITU-R) and is maintained by the International Bureau of Weights and Measures (BIPM) in cooperation with the International Earth reference and Rotation Service (IERS). Contributed measurements from timing centres around the world are used in the determination of UTC, which is adjusted to within 0.9 s of Earth rotation time (UT1) by IERS-determined values of the Earth rotation. The adjustments, made in one second steps known as leap seconds, were implemented in 1972 to permit UT1 to be recovered from broadcast values of UTC for celestial navigation. Current telecommunications and navigation systems utilize continuous timing for their data transmissions; consequently, deliberations have been ongoing within the ITU-R on the issue of modifying the definition of UTC to a continuous time scale. C1 USN, Res Lab, ITU R Working Party 7A, Washington, DC 20375 USA. RP Beard, RL (reprint author), USN, Res Lab, ITU R Working Party 7A, Washington, DC 20375 USA. NR 15 TC 0 Z9 0 U1 0 U2 0 PU IOP PUBLISHING LTD PI BRISTOL PA DIRAC HOUSE, TEMPLE BACK, BRISTOL BS1 6BE, ENGLAND SN 0026-1394 J9 METROLOGIA JI Metrologia PD AUG PY 2011 VL 48 IS 4 BP S125 EP S131 DI 10.1088/0026-1394/48/4/S02 PG 7 WC Instruments & Instrumentation; Physics, Applied SC Instruments & Instrumentation; Physics GA 794QN UT WOS:000292916000003 ER PT J AU Gambis, D Luzum, B AF Gambis, Daniel Luzum, Brian TI Earth rotation monitoring, UT1 determination and prediction SO METROLOGIA LA English DT Article ID ATMOSPHERIC ANGULAR-MOMENTUM; SMOOTHING OBSERVATIONAL DATA; ORIENTATION PARAMETERS; REFERENCE FRAME; SERIES; INTERFEROMETRY; LENGTH; MODEL; VLBI AB Monitoring the Earth's rotation angle is essential in various domains linked to reference systems such as space navigation, precise orbit determinations of artificial Earth satellites including the Global Navigation Satellite Systems (GNSS), positional astronomy and for geophysical studies on time scales ranging from a few hours to decades. Universal Time UT1 is based on the rotation of the Earth on its axis. Historically it was related to mean solar time on the meridian of Greenwich, sometimes known as Greenwich Mean Time. Monitoring Earth orientation, and in particular UT1, is the primary task of the International Earth Rotation and Reference Systems Service (IERS). The Earth Orientation Center is responsible for monitoring Earth orientation parameters (EOPs) including long-term consistency and leap second announcements. The Rapid Service/Prediction Center is in charge of the rapid, near real-time solution and predictions. These two complementary services of the IERS provide Earth orientation information from results derived predominantly from Very Long Baseline Interferometry with valuable input from GNSS observations and global atmospheric angular momentum for both the combination and prediction of EOPs. C1 [Gambis, Daniel] Observ Paris, IERS Earth Orientat Ctr, Paris, France. [Luzum, Brian] USN, Res Lab, IERS Rapid Serv, Predict Ctr, Washington, DC 20375 USA. RP Gambis, D (reprint author), Observ Paris, IERS Earth Orientat Ctr, Paris, France. NR 45 TC 15 Z9 17 U1 1 U2 6 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0026-1394 J9 METROLOGIA JI Metrologia PD AUG PY 2011 VL 48 IS 4 BP S165 EP S170 DI 10.1088/0026-1394/48/4/S06 PG 6 WC Instruments & Instrumentation; Physics, Applied SC Instruments & Instrumentation; Physics GA 794QN UT WOS:000292916000007 ER PT J AU Hohenkerk, CY Hilton, JL AF Hohenkerk, C. Y. Hilton, J. L. TI Time references in US and UK astronomical and navigational almanacs SO METROLOGIA LA English DT Article AB An astronomical or navigational almanac can best be thought of as a device for connecting an observer with celestial objects. For an observer with a known position and time the almanac allows the observer to identify the celestial objects. Conversely, if the observer knows what objects he is observing and when, the almanac allows him to determine his position. In either case, knowledge of the time is crucial in providing this link between the celestial objects and the observer through the almanac. This paper summarizes the various time scales used in the astronomical and nautical almanacs produced jointly by the US Naval Observatory and HM Nautical Almanac Office. C1 [Hohenkerk, C. Y.] UK Hydrog Off, HM Naut Almanac Off, Taunton TA1 2DN, Somerset, England. [Hilton, J. L.] USN Observ, Astron Applicat Dept, Washington, DC 20392 USA. RP Hohenkerk, CY (reprint author), UK Hydrog Off, HM Naut Almanac Off, Admiralty Way, Taunton TA1 2DN, Somerset, England. EM Catherine.Hohenkerk@ukho.gov.uk; James.Hilton@usno.navy.mil NR 18 TC 1 Z9 1 U1 0 U2 0 PU IOP PUBLISHING LTD PI BRISTOL PA DIRAC HOUSE, TEMPLE BACK, BRISTOL BS1 6BE, ENGLAND SN 0026-1394 J9 METROLOGIA JI Metrologia PD AUG PY 2011 VL 48 IS 4 BP S195 EP S199 DI 10.1088/0026-1394/48/4/S10 PG 5 WC Instruments & Instrumentation; Physics, Applied SC Instruments & Instrumentation; Physics GA 794QN UT WOS:000292916000011 ER PT J AU McCarthy, DD AF McCarthy, Dennis D. TI Evolution of timescales from astronomy to physical metrology SO METROLOGIA LA English DT Article ID TIME SCALES; EPHEMERIS AB Astronomy has provided a means to mark the passage of time throughout history. One of the repeating phenomena that makes this possible is the Earth's rotation. The basic variability in its rotational speed, however, makes astronomical techniques unsuitable for timekeeping with the precision required for modern applications. Physical metrology from the first mechanical clocks to the most sophisticated atomic standards of today has assumed a growing role in timekeeping. Along with this progress in technology, more sophisticated concepts of timescales have appeared to take advantage of those improvements. C1 USN Observ, Washington, DC 20392 USA. RP McCarthy, DD (reprint author), USN Observ, 3450 Massachusetts Ave NW, Washington, DC 20392 USA. EM dennis.mccarthy@usno.navy.mil NR 56 TC 5 Z9 5 U1 0 U2 3 PU IOP PUBLISHING LTD PI BRISTOL PA DIRAC HOUSE, TEMPLE BACK, BRISTOL BS1 6BE, ENGLAND SN 0026-1394 J9 METROLOGIA JI Metrologia PD AUG PY 2011 VL 48 IS 4 BP S132 EP S144 DI 10.1088/0026-1394/48/4/S03 PG 13 WC Instruments & Instrumentation; Physics, Applied SC Instruments & Instrumentation; Physics GA 794QN UT WOS:000292916000004 ER PT J AU Lutgendorf, MA Adriano, EM Taylor, BJ AF Lutgendorf, Monica A. Adriano, Elizabeth M. Taylor, Bruce J. TI Prevention and Management of Keloid Scars SO OBSTETRICS AND GYNECOLOGY LA English DT Editorial Material ID HYPERTROPHIC SCARS AB A 31-year-old woman, gravida 3, para 2, at 30 weeks of gestation was referred to our institution with the symptom of rapid growth of her keloid scars during her current pregnancy. She was black and had a surgical history of a cesarean delivery and a right vulvar excision for a benign inclusion cyst. The keloid scarring was present at her pfannenstiel incision and also at the site of her right vulvar excision. The scarring was cosmetically disfiguring and physically painful (Fig. 1). At the time of her repeat cesarean delivery, the keloid scars were excised with assistance from the plastic surgery team (Fig. 2). Immediately after surgery, she was treated by radiation oncology with four daily fractions of radiation therapy. The first dose was administered on the day of surgery to limit risk of recurrence. The radiation therapy consisted of 450-500 cGy fractions with a 1- to 2-cm margin, using 6-9 MeV electrons and appropriate bolus material to ensure adequate dose from skin to depth. The patient did well and was discharged after 4 days. Her postoperative course was uncomplicated and she had good wound healing with no recurrence of the keloids at her 15-month postoperative visit (Fig. 3). The patient also had a left preauricular keloid that was excised by plastic surgery 8 months after her delivery, and it was also treated with adjuvant external beam radiation therapy with good cosmetic result. C1 [Lutgendorf, Monica A.] USN, Med Ctr Portsmouth, Dept Obstet & Gynecol, Portsmouth, VA 23708 USA. USN, Med Ctr Portsmouth, Dept Plast & Reconstruct Surg, Portsmouth, VA 23708 USA. RP Lutgendorf, MA (reprint author), USN, Med Ctr Portsmouth, Dept Obstet & Gynecol, 620 John Paul Jones Circle, Portsmouth, VA 23708 USA. EM malutgendorf@gmail.com FU The Chief Navy Bureau of Medicine and Surgery, Washington, DC FX The Chief Navy Bureau of Medicine and Surgery, Washington, DC, Clinical Investigation Program sponsored this study. NR 17 TC 3 Z9 3 U1 1 U2 2 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA SN 0029-7844 J9 OBSTET GYNECOL JI Obstet. Gynecol. PD AUG PY 2011 VL 118 IS 2 BP 351 EP 356 DI 10.1097/AOG.0b013e3182255614 PN 1 PG 6 WC Obstetrics & Gynecology SC Obstetrics & Gynecology GA 795FB UT WOS:000292956900022 PM 21775852 ER PT J AU Kennedy, WG Trafton, JG AF Kennedy, William G. Trafton, J. Gregory TI How Long Is a Moment: The Perception and Reality of Task-Related Absences SO INTERNATIONAL JOURNAL OF SOCIAL ROBOTICS LA English DT Article DE Time estimation; Time perception; Human-robot interaction; Walking AB We have investigated actual and perceived human performance associated with a simple task involving walking and applied the developed knowledge to a human-robot interaction. Based on experiments involving walking at a "purposeful and comfortable" pace, parameters were determined for a trapezoidal model of walking: starting from standing still, accelerating to a constant pace, walking at a constant pace, and decelerating to a stop. We also collected data on humans' evaluation of the accomplishment of a simple task involving walking: determining the transitions from having taken too short a period of time to an appropriate time and from having taken an appropriate time to having taken too long. People were found to be accurate in estimating the task duration for short tasks, but to underestimate the duration of longer tasks. This information was applied to a human-robot interaction involving a human leaving for a "moment" and the robot knows how long the task should take and how time is evaluated by a human. C1 [Kennedy, William G.; Trafton, J. Gregory] Naval Res Lab, Washington, DC 20585 USA. RP Kennedy, WG (reprint author), Naval Res Lab, 4555 Overlook Ave SW, Washington, DC 20585 USA. EM wkennedy@gmu.edu FU National Research Council Research Associateship Award; Office of Naval Research [N001406WZ20001, N0001406WR20156] FX This work was performed while the first author held a National Research Council Research Associateship Award and was partially supported by the Office of Naval Research under N001406WZ20001 and N0001406WR20156. John Hutchison contributed to the background material, Kristina O'Connell conducted the experiments, and Malcolm McCurry prepared the videos and program to obtain evaluation data. The views and conclusions contained in this document should not be interpreted as necessarily representing official policies, either expressed or implied, of the US Navy or the National Research Council. NR 22 TC 1 Z9 1 U1 1 U2 2 PU SPRINGER PI DORDRECHT PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS SN 1875-4791 EI 1875-4805 J9 INT J SOC ROBOT JI Int. J. Soc. Robot. PD AUG PY 2011 VL 3 IS 3 BP 243 EP 252 DI 10.1007/s12369-011-0098-7 PG 10 WC Robotics SC Robotics GA V31OX UT WOS:000208894000005 ER PT J AU Kruse, FA Taranik, JV Coolbaugh, M Michaels, J Littlefield, EF Calvin, WM Martini, BA AF Kruse, Fred A. Taranik, James V. Coolbaugh, Mark Michaels, Joshua Littlefield, Elizabeth F. Calvin, Wendy M. Martini, Brigette A. TI Effect of Reduced Spatial Resolution on Mineral Mapping Using Imaging Spectrometry-Examples Using Hyperspectral Infrared Imager (HyspIRI)-Simulated Data SO REMOTE SENSING LA English DT Article DE imaging spectrometry; hyperspectral; HSI; mineral mapping; HyspIRI simulation; spatial resolution modeling ID STEAMBOAT-SPRINGS; AVIRIS DATA; NEVADA; EXPLORATION; VEGETATION; DISTRICT; ROCKS AB The Hyperspectral Infrared Imager (HyspIRI) is a proposed NASA satellite remote sensing system combining a visible to shortwave infrared (VSWIR) imaging spectrometer with over 200 spectral bands between 0.38 and 2.5 mu m and an 8-band thermal infrared (TIR) multispectral imager, both at 60 m spatial resolution. Short Wave Infrared (SWIR) (2.0-2.5 mu m) simulation results are described here using Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) data in preparation for the future launch. The simulated data were used to assess the effect of the HyspIRI 60 m spatial resolution on the ability to identify and map minerals at hydrothermally altered and geothermal areas. Mineral maps produced using these data successfully detected and mapped a wide variety of characteristic minerals, including jarosite, alunite, kaolinite, dickite, muscovite-illite, montmorillonite, pyrophyllite, calcite, buddingtonite, and hydrothermal silica. Confusion matrix analysis of the datasets showed overall classification accuracy ranging from 70 to 92% for the 60 m HyspIRI simulated data relative to 15 m spatial resolution data. Classification accuracy was lower for similar minerals and smaller areas, which were not mapped well by the simulated 60 m HyspIRI data due to blending of similar signatures and spectral mixing with adjacent pixels. The simulations demonstrate that HyspIRI SWIR data, while somewhat limited by their relatively coarse spatial resolution, should still be useful for mapping hydrothermal/geothermal systems, and for many other geologic applications requiring mineral mapping. C1 [Kruse, Fred A.] USN, Postgrad Sch, Dept Phys, Monterey, CA 93943 USA. [Kruse, Fred A.] USN, Postgrad Sch, Ctr Remote Sensing, Monterey, CA 93943 USA. [Kruse, Fred A.; Taranik, James V.; Coolbaugh, Mark; Michaels, Joshua; Littlefield, Elizabeth F.; Calvin, Wendy M.] Univ Nevada, Dept Geol Sci & Engn, Reno, NV 89557 USA. [Kruse, Fred A.; Taranik, James V.; Coolbaugh, Mark; Michaels, Joshua; Littlefield, Elizabeth F.; Calvin, Wendy M.] Univ Nevada, Arthur Brant Lab Explorat Geophys, Reno, NV 89557 USA. [Coolbaugh, Mark] Renaissance Gold Inc, Reno, NV 89502 USA. [Martini, Brigette A.] Ormat Nevada Inc, Reno, NV 89557 USA. RP Kruse, FA (reprint author), USN, Postgrad Sch, Dept Phys, 833 Dyer Rd, Monterey, CA 93943 USA. EM fakruse@nps.edu; jvtaranik@cs.com; sereno@dim.com; joshua.michaels@gmail.com; eflittlefield@gmail.com; wcalvin@unr.edu; bmartini@ormat.com FU NASA at the University of Nevada, Reno (UNR) [NNX10AF99G]; Arthur Brant Laboratory for Exploration Geophysics at UNR FX This research was partially sponsored by NASA under NASA Grant NNX10AF99G at the University of Nevada, Reno (UNR). Portions of this effort were also partially supported by the Arthur Brant Laboratory for Exploration Geophysics at UNR. Additional research and manuscript preparation was done after the corresponding author changed employment from UNR to the Naval Postgraduate School, Monterey, CA. Ormat Nevada Inc. provided access to their geothermal properties for reconnaissance, field verification, and field spectral measurements. NR 56 TC 16 Z9 17 U1 1 U2 24 PU MDPI AG PI BASEL PA POSTFACH, CH-4005 BASEL, SWITZERLAND SN 2072-4292 J9 REMOTE SENS-BASEL JI Remote Sens. PD AUG PY 2011 VL 3 IS 8 BP 1584 EP 1602 DI 10.3390/rs3081584 PG 19 WC Remote Sensing SC Remote Sensing GA 978NZ UT WOS:000306751500003 ER PT J AU Ward, N Tran, A Abad, A Lee, EW Hahn, M Fordan, E Es-Said, OS AF Ward, N. Tran, A. Abad, A. Lee, E. W. Hahn, M. Fordan, E. Es-Said, O. S. TI The Effects of Retrogression and Reaging on Aluminum Alloy 2099 (C458) SO JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE LA English DT Article DE aluminum-lithium alloys; heat treatable aluminum alloys; retrogression and reaging AB The objective of this study was to investigate the feasibility of performing retrogression and reaging (RRA) heat treatments on 2099 aluminum-lithium alloy. The retrogression temperatures were 200-250 A degrees C and retrogression times were 5-60 min. Half of the samples were exposed to a salt fog environment. Interestingly, the samples exposed to salt spray had consistently higher mechanical tensile properties than those which were not exposed. C1 [Ward, N.; Tran, A.; Es-Said, O. S.] Loyola Marymount Univ, Dept Mech Engn, Los Angeles, CA 90045 USA. [Lee, E. W.] Naval Air Warfare, Naval Air Syst Command, Patuxent River, MD 20670 USA. [Abad, A.; Hahn, M.; Fordan, E.] Northrop Grumman Air Combat Syst, El Segundo, CA 90045 USA. RP Ward, N (reprint author), Loyola Marymount Univ, Dept Mech Engn, Los Angeles, CA 90045 USA. EM oessaid@lmu.edu NR 14 TC 9 Z9 16 U1 0 U2 7 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1059-9495 J9 J MATER ENG PERFORM JI J. Mater. Eng. Perform. PD AUG PY 2011 VL 20 IS 6 BP 989 EP 996 DI 10.1007/s11665-010-9737-7 PG 8 WC Materials Science, Multidisciplinary SC Materials Science GA 792MN UT WOS:000292749800017 ER PT J AU Ward, N Tran, A Abad, A Lee, EW Hahn, M Fordan, E Es-Said, O AF Ward, N. Tran, A. Abad, A. Lee, E. W. Hahn, M. Fordan, E. Es-Said, O. TI The Effects of Retrogression and Reaging on Aluminum Alloy 2195 SO JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE LA English DT Article DE aluminum lithium alloys; retrogression and reaging; 2195 and 2099 alloys ID STRESS-CORROSION AB A retrogression and reaging (RRA) treatment was performed on 2195 Al-Li Alloy. The exposure times were from 5 to 60 min, and the temperatures were from 200 to 250 A degrees C. Samples that were exposed to a salt spray test had overall similar mechanical properties as compared to those that were not exposed. The percent elongation, however, was significantly deteriorated due to the salt spray exposure. The mechanical properties of the 2195 samples were compared to those of 2099 samples exposed to similar treatments in an earlier study. C1 [Ward, N.; Tran, A.; Es-Said, O.] Loyola Marymount Univ, Dept Mech Engn, Los Angeles, CA 90045 USA. [Lee, E. W.] Naval Air Warfare, Naval Air Syst Command, Patuxent River, MD 20670 USA. [Fordan, E.] Northrop Grumman Aerosp Syst Air Combat Syst, El Segundo, CA 90045 USA. RP Ward, N (reprint author), Loyola Marymount Univ, Dept Mech Engn, Los Angeles, CA 90045 USA. EM oessaid@lmu.edu NR 24 TC 1 Z9 1 U1 4 U2 12 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1059-9495 J9 J MATER ENG PERFORM JI J. Mater. Eng. Perform. PD AUG PY 2011 VL 20 IS 6 BP 1003 EP 1014 DI 10.1007/s11665-010-9739-5 PG 12 WC Materials Science, Multidisciplinary SC Materials Science GA 792MN UT WOS:000292749800019 ER PT J AU Brownell, CJ Su, LK AF Brownell, Cody J. Su, Lester K. TI Measurements of multiple mole fraction fields in a turbulent jet by simultaneous planar laser-induced fluorescence and planar Rayleigh scattering SO MEASUREMENT SCIENCE AND TECHNOLOGY LA English DT Article DE planar laser imaging; turbulent mixing; multi-species mixing; differential diffusion; Rayleigh scattering; laser-induced fluorescence ID ACETONE; DIFFUSION; FLOWS; PHOSPHORESCENCE; PRESSURE; FLAMES; VAPOR AB This paper presents two-dimensional measurements of all individual mole fractions in a three-species, non-reacting turbulent flow, using planar laser-induced fluorescence (PLIF) and planar laser Rayleigh scattering. The flow is an axisymmetric jet of acetone and helium in an air coflow. PLIF measures the acetone mole fraction, while Rayleigh scattering measures a linear combination of the acetone and helium mole fractions. The simultaneous implementation of these techniques allows for the calculation of the helium and air mole fraction fields. The results of this diagnostic method are being used for the study of multicomponent molecular transport effects in turbulent fluid mixing. C1 [Brownell, Cody J.] USN Acad, Dept Mech Engn, Annapolis, MD 21402 USA. [Su, Lester K.] Johns Hopkins Univ, Dept Mech Engn, Appl Fluid Imaging Lab, Baltimore, MD 21218 USA. RP Brownell, CJ (reprint author), USN Acad, Dept Mech Engn, 590 Holloway Rd, Annapolis, MD 21402 USA. EM brownell@usna.edu FU National Science Foundation [CBET-0348208] FX This work is supported by the National Science Foundation through grant CBET-0348208. NR 30 TC 1 Z9 1 U1 0 U2 4 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0957-0233 EI 1361-6501 J9 MEAS SCI TECHNOL JI Meas. Sci. Technol. PD AUG PY 2011 VL 22 IS 8 AR 085402 DI 10.1088/0957-0233/22/8/085402 PG 15 WC Engineering, Multidisciplinary; Instruments & Instrumentation SC Engineering; Instruments & Instrumentation GA 792UD UT WOS:000292775000020 ER PT J AU Nasir, M Mott, DR Kennedy, MJ Golden, JP Ligler, FS AF Nasir, Mansoor Mott, David R. Kennedy, Matthew J. Golden, Joel P. Ligler, Frances S. TI Parameters affecting the shape of a hydrodynamically focused stream SO MICROFLUIDICS AND NANOFLUIDICS LA English DT Article DE Flow focusing; Angle of confluence; Converging channels; Inertial effects; Laminar flow; Symmetric ID MICROFLUIDIC DEVICES; T-SENSOR; FLOW; MICROCHANNELS; CONFLUENCE; SURFACES; SCALE; CHIP AB Even at low Reynolds numbers, momentum can impact the shape of hydrodynamically focused flow. Both theoretical and experimental characterization of hydrodynamic focusing in microchannels at Reynolds numbers a parts per thousand currency sign25 revealed the important parameters that affect the shape of the focused layer. A series of symmetric and asymmetric microfluidic channels with two converging streams were fabricated with different angles of confluence at the junction. The channels were used to study the characteristics of Y-type microchannels for flow-focusing. Computational analysis and experimental results gathered using confocal microscopy and particle image velocimetry indicated that the orientation of the sheath and the sample stream inlets, as well as the absolute flow velocities, determine the curvature in the concentration distribution of the focused stream. Decreasing the angle of confluence between sheath and sample, as well as reducing the overall Reynolds number, resulted in a flat interface between sheath and focused fluids. Alignment of the faster flowing sheath fluid channel with the main channel also reduced the inertial effects and produced a focused stream with a flat concentration profile. Control over the shape of the focused stream is important in many biosensors and lab-on-a-chip devices that rely on hydrodynamic focusing for increased detection sensitivity. C1 [Nasir, Mansoor; Golden, Joel P.; Ligler, Frances S.] USN, Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. [Mott, David R.] USN, Res Lab, Computat Phys & Fluid Dynam Lab, Washington, DC 20375 USA. [Kennedy, Matthew J.] USN, Res Lab, Div Chem, Washington, DC 20375 USA. [Kennedy, Matthew J.] CNR, Ottawa, ON, Canada. RP Ligler, FS (reprint author), USN, Res Lab, Ctr Bio Mol Sci & Engn, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM frances.ligler@nrl.navy.mil OI Kennedy, Matthew J./0000-0002-6477-9936; Mott, David/0000-0002-7863-456X FU Defense Threat Reduction Agency (DTRA) [AA07CBT015] FX This project is funded by the Defense Threat Reduction Agency (DTRA #AA07CBT015). The authors would like to thank Dr. James W Fleming at NRL for use of the PIV instrument. Dr. Matthew Kennedy is a National Research Council (NRC) Post-doctoral Fellow. The views are those of the authors and do not represent opinion or policy of the US Navy or Department of Defense. NR 39 TC 11 Z9 11 U1 0 U2 20 PU SPRINGER HEIDELBERG PI HEIDELBERG PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY SN 1613-4982 J9 MICROFLUID NANOFLUID JI Microfluid. Nanofluid. PD AUG PY 2011 VL 11 IS 2 BP 119 EP 128 DI 10.1007/s10404-011-0778-5 PG 10 WC Nanoscience & Nanotechnology; Instruments & Instrumentation; Physics, Fluids & Plasmas SC Science & Technology - Other Topics; Instruments & Instrumentation; Physics GA 789ZZ UT WOS:000292559600001 ER PT J AU Cullenbine, C Wood, RK Newman, A AF Cullenbine, Christopher Wood, R. Kevin Newman, Alexandra TI A sliding time window heuristic for open pit mine block sequencing SO OPTIMIZATION LETTERS LA English DT Article DE Mine scheduling; Mine planning; Open pit mining; Surface mining; Integer programming applications AB The open pit mine block sequencing problem (OPBS) seeks a discretetime production schedule that maximizes the net present value of the orebody extracted from an open-pit mine. This integer program (IP) discretizes the mine's volume into blocks, imposes precedence constraints between blocks, and limits resource consumption in each time period. We develop a "sliding time window heuristic" to solve this IP approximately. The heuristic recursively defines, solves and partially fixes an approximating model having: (i) fixed variables in early time periods, (ii) an exact submodel defined over a "window" of middle time periods, and (iii) a relaxed submodel in later time periods. The heuristic produces near-optimal solutions (typically within 2% of optimality) for model instances that standard optimization software fails to solve. Furthermore, it produces these solutions quickly, even though our OPBS model enforces standard upper-bounding constraints on resource consumption along with less standard, but important, lower-bounding constraints. C1 [Cullenbine, Christopher; Newman, Alexandra] Colorado Sch Mines, Div Econ & Business, Golden, CO 80401 USA. [Wood, R. Kevin] USN, Dept Operat Res, Postgrad Sch, Monterey, CA 93943 USA. RP Cullenbine, C (reprint author), Colorado Sch Mines, Div Econ & Business, Golden, CO 80401 USA. EM ccullenb@mymail.mines.edu; kwood@nps.edu; newman@mines.edu OI Wood, Kevin/0000-0002-0311-8712 NR 24 TC 23 Z9 23 U1 0 U2 4 PU SPRINGER HEIDELBERG PI HEIDELBERG PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY SN 1862-4472 J9 OPTIM LETT JI Optim. Lett. PD AUG PY 2011 VL 5 IS 3 SI SI BP 365 EP 377 DI 10.1007/s11590-011-0306-2 PG 13 WC Operations Research & Management Science; Mathematics, Applied SC Operations Research & Management Science; Mathematics GA 791WJ UT WOS:000292698600002 ER PT J AU Nainani, A Irisawa, T Bennett, BR Boos, JB Ancona, MG Saraswat, KC AF Nainani, Aneesh Irisawa, Toshifumi Bennett, Brian R. Boos, J. Brad Ancona, Mario G. Saraswat, Krishna C. TI Study of Shubnikov-de Haas oscillations and measurement of hole effective mass in compressively strained InXGa1-XSb quantum wells SO SOLID-STATE ELECTRONICS LA English DT Article DE Field effect transistors; III-V CMOS; III-V pMOSFET; Shubnikov-de Haas; Hole effective mass; Cyclotron resonance; III-V ID 2-DIMENSIONAL ELECTRON-GAS AB InXGa1-XSb has the highest hole mobility amongst all III-V semiconductors which can be enhanced further with the use of strain. The use of confinement and strain in InXGa1-XSb quantum wells lifts the degeneracy between the light and heavy hole bands which leads to reduction in the hole effective mass in the lowest occupied band and an increase in the mobility. We present magnetotransport measurements on compressively strained InXGa1-XSb and GaSb quantum wells. Hall-bar and Van de Pauw structures were fabricated and Shubnikov-de Haas oscillations in the temperature range of T = 2-10 K for magnetic fields of B = 0-9 T were measured. The reduction of effective hole mass with strain was quantified. These results are in excellent agreement with modeling results from band structure calculations of the effective hole mass in the presence of strain and confinement. (C) 2011 Elsevier Ltd. All rights reserved. C1 [Nainani, Aneesh; Irisawa, Toshifumi; Saraswat, Krishna C.] Stanford Univ, Dept Elect Engn, Ctr Integrated Syst, Stanford, CA 94305 USA. [Bennett, Brian R.; Boos, J. Brad; Ancona, Mario G.] USN, Res Lab, Washington, DC 20375 USA. RP Nainani, A (reprint author), Stanford Univ, Dept Elect Engn, Ctr Integrated Syst, Stanford, CA 94305 USA. EM nainani@stanford.edu RI Bennett, Brian/A-8850-2008 OI Bennett, Brian/0000-0002-2437-4213 FU Office of Naval Research; Intel Corporation FX This work was partially supported by the Office of Naval Research. A. Nainani would like to thank Intel Corporation for a PhD fellowship and Rick Pam for providing the Agilent 4155C used in this research. NR 12 TC 1 Z9 1 U1 2 U2 11 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0038-1101 J9 SOLID STATE ELECTRON JI Solid-State Electron. PD AUG PY 2011 VL 62 IS 1 BP 138 EP 141 DI 10.1016/j.sse.2011.04.005 PG 4 WC Engineering, Electrical & Electronic; Physics, Applied; Physics, Condensed Matter SC Engineering; Physics GA 788KO UT WOS:000292444000024 ER PT J AU Moore, EZ Murphy, KD Nichols, JM AF Moore, Edward Z. Murphy, Kevin D. Nichols, Jonathan M. TI Crack identification in a freely vibrating plate using Bayesian parameter estimation SO MECHANICAL SYSTEMS AND SIGNAL PROCESSING LA English DT Article DE Bayesian statistics; Plate vibration; Crack identification; Structural health monitoring ID DAMAGE DETECTION; PROBABILISTIC APPROACH AB In this paper a new approach is proposed for identifying the presence and location of a crack in a simply supported plate undergoing free vibration. Specifically, the approach uses a Markov-chain Monte-Carlo implementation of Bayes' Rule to estimate the crack parameters (i.e., its location, orientation, and size) and their probability distributions. Special attention is paid to developing a fast and accurate forward model for the response of the cracked plate. To generate the required time series, a semi-analytical free response is calculated using an FEM based eigen-solution. To speed up the simulations, modified elements are used at the crack tips; this permits a more course mesh without sacrificing accuracy. The approach is demonstrated to be effective at identifying all of the crack parameters. Furthermore, a natural by-product of this method is that it also provides a confidence (credible) interval for each of these parameters. The results show the utility and accuracy of this method in identifying cracks of various sizes, orientations, and locations. (C) 2011 Elsevier Ltd. All rights reserved. C1 [Moore, Edward Z.; Murphy, Kevin D.] Univ Connecticut, Dept Mech Engn, Storrs, CT 06269 USA. [Nichols, Jonathan M.] USN, Res Lab, Washington, DC 20375 USA. RP Murphy, KD (reprint author), Univ Connecticut, Dept Mech Engn, Storrs, CT 06269 USA. EM kdm@engr.uconn.edu FU Office of Naval Research [N00014-10-WX-2-0147, N00014-09-1-0616] FX The author's gratefully acknowledge the financial support of the Office of Naval Research under contracts N00014-10-WX-2-0147 and N00014-09-1-0616. NR 21 TC 10 Z9 12 U1 1 U2 7 PU ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD PI LONDON PA 24-28 OVAL RD, LONDON NW1 7DX, ENGLAND SN 0888-3270 J9 MECH SYST SIGNAL PR JI Mech. Syst. Signal Proc. PD AUG PY 2011 VL 25 IS 6 BP 2125 EP 2134 DI 10.1016/j.ymssp.2011.01.016 PG 10 WC Engineering, Mechanical SC Engineering GA 783HI UT WOS:000292071700016 ER PT J AU Michalowicz, JV Nichols, JM Bucholtz, F Olson, CC AF Michalowicz, J. V. Nichols, J. M. Bucholtz, F. Olson, C. C. TI A general Isserlis theorem for mixed-Gaussian random variables SO STATISTICS & PROBABILITY LETTERS LA English DT Article DE Mixed-Gaussian distribution; Isserlis' theorem; Wick's theorem ID AUTO-BISPECTRAL DENSITY; HIGHER-ORDER SPECTRA; WICKS THEOREM; TIME-SERIES; NONLINEARITY; SYSTEMS AB This work generalizes a widely used result derived by L. Isserlis for the expectations of products of jointly Gaussian random variables by extending it to include mixed-Gaussian random variables. Published by Elsevier B.V. C1 [Nichols, J. M.; Bucholtz, F.; Olson, C. C.] USN, Res Lab, Washington, DC 20375 USA. [Michalowicz, J. V.; Olson, C. C.] GTEC Inc, Crofton, MD 21114 USA. RP Nichols, JM (reprint author), USN, Res Lab, 4555 Overlook Ave, Washington, DC 20375 USA. EM jonathan.nichols@nrl.navy.mil FU Naval Research Laboratory FX The authors would like to acknowledge funding from the Naval Research Laboratory. The authors would also like to acknowledge some very helpful comments made by an anonymous reviewer on an earlier version of this manuscript. NR 26 TC 3 Z9 3 U1 1 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0167-7152 J9 STAT PROBABIL LETT JI Stat. Probab. Lett. PD AUG PY 2011 VL 81 IS 8 BP 1233 EP 1240 DI 10.1016/j.spl.2011.03.022 PG 8 WC Statistics & Probability SC Mathematics GA 785MI UT WOS:000292232700046 ER PT J AU Kwon, YW Esmaeili, Y Park, CM AF Kwon, Y. W. Esmaeili, Y. Park, C. M. TI Stress-Strain Behavior of an Aluminum Alloy Under Transient Strain-Rates SO JOURNAL OF PRESSURE VESSEL TECHNOLOGY-TRANSACTIONS OF THE ASME LA English DT Article ID MECHANICAL-PROPERTIES; DUCTILITY AB Because most structures are subjected to transient strain-rate loading, an experimental study was conducted to investigate the stress-strain behaviors of an aluminum alloy undergoing varying strain-rate loading. To this end, uniaxial tensile loading was applied to coupons of dog-bone shape such that each coupon underwent two or three different strain-rates, i.e., one rate after another. As a basis, a series of single-strain-rate tests was also conducted with strain-rates of 0.1-10.0 s(-1). When the material experienced multistrain-rate loading, the stress-strain curves were significantly different from any single-strain-rate stress-strain curve. The strain-rate history affected the stress-strain curves under multistrain-rate loading. As a result, some simple averaging of single-strain-rate curves did not predict the actual multistrain-rate stress-strain curve properly. Furthermore, the fracture strain under multistrain-rate loading was significantly different from that under any single-strain-rate case. Depending on the applied strain-rates and their sequences, the former was much greater or less than the latter. A technique was proposed based on the residual plastic strain and plastic energy density in order to predict the fracture strain under multistrain-rate loading. The predicted fracture strains generally agreed well with the experimental data. Another observation that was made was that the unloading stress-strain curve was not affected by the previous strain-rate history. [DOI: 10.1115/1.4003470] C1 [Kwon, Y. W.; Park, C. M.] USN, Postgrad Sch, Dept Mech & Aerosp Engn, Monterey, CA 93943 USA. [Esmaeili, Y.] Univ Calif Santa Barbara, Dept Mech & Environm Engn, Santa Barbara, CA 93106 USA. RP Kwon, YW (reprint author), USN, Postgrad Sch, Dept Mech & Aerosp Engn, Monterey, CA 93943 USA. FU ONR; NSWC-Carderock Division FX This work was sponsored by the ONR Solid Mechanics Program as well as the NSWC-Carderock Division. The authors greatly appreciate their support. NR 7 TC 0 Z9 0 U1 1 U2 3 PU ASME-AMER SOC MECHANICAL ENG PI NEW YORK PA THREE PARK AVE, NEW YORK, NY 10016-5990 USA SN 0094-9930 J9 J PRESS VESS-T ASME JI J. Press. Vessel Technol.-Trans. ASME PD AUG PY 2011 VL 133 IS 4 AR 044501 DI 10.1115/1.4003470 PG 4 WC Engineering, Mechanical SC Engineering GA 774RK UT WOS:000291403600017 ER PT J AU Knipling, KE Fonda, RW AF Knipling, K. E. Fonda, R. W. TI Microstructural Evolution in Ti-5111 Friction Stir Welds SO METALLURGICAL AND MATERIALS TRANSACTIONS A-PHYSICAL METALLURGY AND MATERIALS SCIENCE LA English DT Article ID STRENGTH ALUMINUM-ALLOYS; MECHANICAL-PROPERTIES; TITANIUM-ALLOYS; PURE TITANIUM; PLASTIC-DEFORMATION; TEXTURE DEVELOPMENT; STAINLESS-STEEL; GRAIN-STRUCTURE; TI-6AL-4V; TEMPERATURES AB The microstructural evolution occurring during friction stir welding of a near-alpha titanium alloy, Ti-5111, has been examined by backscattered electron imaging and electron backscatter diffraction. The unaffected baseplate (BP) microstructure consists of millimeter-scale prior beta grains containing similar to 100 mu m large colonies of aligned alpha laths, related to each other by a strain-accommodating Burgers orientation relationship. The alpha laths are separated by fine, 100 to 150-nm-thick, interlath beta ribs. A heat-affected zone (HAZ) is observed similar to 1.5 to 2.5 mm from the tool surface, characterized by a thickening of the beta ribs and the formation of secondary alpha platelets within them closer to the tool. There is a narrow thermomechanically affected zone (TMAZ), comprised of outer and inner regions, observed similar to 1.0 to 1.5 mm from the tool surface. Deformation is first observed in a similar to 200-mu m-wide outer TMAZ, where the microstructure is refined through an increase in fine secondary (alpha laths) alpha laths and the lattice orientations rotate to align the close-packed < 11 (2) over bar0 > directions with the shear direction (SD). Continued deformation closer to the tool produces periodic shear bands within a similar to 300-mu m-wide inner TMAZ, resulting in alternating regions of material that are deformed below and above the beta transus. Material in the stir zone (SZ) within similar to 1 mm of the tool surface consists of fine (similar to 10 to 20-mu m diameter) equiaxed prior beta grains that are delineated by similar to 500-nm-thick alpha and contain 150-500-nm thick alpha laths. The texture exhibits both D-1(112)[111] bcc and P-1(1100)[1120] hcp shear texture components, indicating that this material exceeded the beta transus during welding. C1 [Knipling, K. E.; Fonda, R. W.] USN, Res Lab, Washington, DC 20375 USA. RP Knipling, KE (reprint author), USN, Res Lab, Code 6355,4555 Overlook Ave SW, Washington, DC 20375 USA. EM keith.knipling@nrl.navy.mil FU Office of Naval Research FX This research is supported by the Office of Naval Research. The authors would also like to acknowledge Mr. K. Klug from Concurrent Technologies Corporation and Mr. E. Czyryca from the Naval Surface Warfare Center, Carderock Division for supplying the plate used in this study. In addition, we would like to thank Mr. L. Levenberry for his assistance with preparing the samples and Dr. D. Rowenhorst for useful discussions. NR 64 TC 11 Z9 11 U1 3 U2 23 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1073-5623 J9 METALL MATER TRANS A JI Metall. Mater. Trans. A-Phys. Metall. Mater. Sci. PD AUG PY 2011 VL 42A IS 8 BP 2312 EP 2322 DI 10.1007/s11661-011-0630-2 PG 11 WC Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering SC Materials Science; Metallurgy & Metallurgical Engineering GA 778LA UT WOS:000291704200022 ER PT J AU Su, JQ Swaminathan, S Menon, SK McNelley, TR AF Su, Jianqing Swaminathan, Srinivasan Menon, Sarath K. McNelley, Terry R. TI The Effect of Concurrent Straining on Phase Transformations in NiAl Bronze During the Friction Stir Processing Thermomechanical Cycle SO METALLURGICAL AND MATERIALS TRANSACTIONS A-PHYSICAL METALLURGY AND MATERIALS SCIENCE LA English DT Article ID NICKEL-ALUMINUM BRONZE; ULTRAHIGH CARBON-STEELS; RECRYSTALLIZATION; MICROSTRUCTURE; DEFORMATION; CRYSTALLOGRAPHY; TEMPERATURE; BEHAVIOR; ALLOY AB Equivalent strains up to a value of a parts per thousand 2.7 were determined by evaluation of the shape changes of the phases in a duplex alpha(fcc)/beta(bcc) microstructure formed ahead of the pin tool extraction site during the friction stir processing (FSP) thermomechanical cycle in a cast NiAl bronze alloy. Correlation of the local strains with volume fractions of the various microstructure constituents in this alloy shows that the concurrent straining of FSP results in acceleration of the alpha + beta -> beta reaction in the thermomechanically affected zone (TMAZ) ahead of the pin extraction site. The resulting volume fraction of beta (as determined by the volume fraction of its transformation products formed during post-FSP cooling) corresponds closely to the volume fraction expected for the peak stir zone temperature measured separately by means of thermocouples embedded within the tool pin profile along the tool path. The stir zone (SZ) in this material exhibits near-equilibrium microstructures despite brief dwells near the peak temperature (T (peak) a parts per thousand 0.95T (melt)), reflecting large local strains and strain rates associated with this process. C1 [Su, Jianqing] Missouri Univ Sci & Technol, Rolla, MO 65409 USA. [Swaminathan, Srinivasan] Gen Elect Global Res, Bangalore 560066, Karnataka, India. [Menon, Sarath K.; McNelley, Terry R.] Naval Postgrad Sch, Dept Mech & Aerosp Engn, Monterey, CA 93943 USA. RP Su, JQ (reprint author), Missouri Univ Sci & Technol, Rolla, MO 65409 USA. EM tmcnelley@nps.edu FU Defense Advanced Projects Agency (DARPA); Office of Naval Research (ONR) [N00014-06-WR-2-0196, N00014-09-WR20201] FX The authors acknowledge prior support and funding for this work from the Defense Advanced Projects Agency (DARPA), with Dr. Leo Christodoulou as program sponsor, and current support from the Office of Naval Research (ONR Contract Nos. N00014-06-WR-2-0196 and N00014-09-WR20201), with Drs. Julie Christodoulou and William Mullins as program officers. NR 32 TC 8 Z9 8 U1 1 U2 8 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1073-5623 J9 METALL MATER TRANS A JI Metall. Mater. Trans. A-Phys. Metall. Mater. Sci. PD AUG PY 2011 VL 42A IS 8 BP 2420 EP 2430 DI 10.1007/s11661-011-0638-7 PG 11 WC Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering SC Materials Science; Metallurgy & Metallurgical Engineering GA 778LA UT WOS:000291704200031 ER PT J AU Onuegbu, J Fu, AQ Glembocki, O Pokes, S Alexson, D Hosten, CM AF Onuegbu, Jonathan Fu, Anqie Glembocki, Orest Pokes, Shaka Alexson, Dimitri Hosten, Charles M. TI Investigation of chemically modified barium titanate beads as surface-enhanced Raman scattering (SERS) active substrates for the detection of benzene thiol, 1,2-benzene dithiol, and rhodamine 6G SO SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY LA English DT Article DE Surface-enhanced Raman; SEM; Benzene thiol ID SINGLE-MOLECULE DETECTION; SILVER FILMS; ELECTROCHEMICAL PREPARATION; GOLD NANOPARTICLES; SPECTROSCOPY; AG; ACID; TIP; FABRICATION; ELECTRODES AB SERS active surfaces were prepared by depositing silver films using Tollen's reaction on to barium titanate beads. The SERS activity of the resulting surfaces was probed using two thiols (benzene thiol and 1,2-benzene dithiol) and rhodamine 6G. The intensity of the SERS signal for the three analytes was investigated as a function of silver deposition time. The results indicate that the SERS intensity increased with increasing thickness of the silver film until a maximum signal intensity was achieved; additional silver deposition resulted in a decrease in the SERS intensity for all of the studied molecules. SEM measurement of the Ag coated barium titanate beads, as a function of silver deposition time, indicate that maximum SERS intensity corresponded with the formation of atomic scale islands of silver nanoparticles. Complete silver coverage of the beads resulted in a decreased SERS signal and the most intense SERS signals were observed at deposition times of 30 min for the thiols and 20 min for rhodamine 6G. (C) 2011 Elsevier B.V. All rights reserved. C1 [Onuegbu, Jonathan; Hosten, Charles M.] Howard Univ, Dept Chem, Washington, DC 20059 USA. [Fu, Anqie; Glembocki, Orest; Pokes, Shaka; Alexson, Dimitri] USN, Div Elect, Res Lab, Washington, DC USA. RP Hosten, CM (reprint author), Howard Univ, Dept Chem, Washington, DC 20059 USA. EM chosten@howard.edu FU DARPA/MTO FX This research was supported by Dr. Dennis Polla of DARPA/MTO. NR 53 TC 5 Z9 5 U1 2 U2 38 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 1386-1425 J9 SPECTROCHIM ACTA A JI Spectroc. Acta Pt. A-Molec. Biomolec. Spectr. PD AUG PY 2011 VL 79 IS 3 BP 456 EP 461 DI 10.1016/j.saa.2011.03.009 PG 6 WC Spectroscopy SC Spectroscopy GA 780CQ UT WOS:000291832500012 PM 21531612 ER PT J AU Chattopadhyay, R de la Vega, P Paik, SH Murata, Y Ferguson, EW Richie, TL Ooi, GT AF Chattopadhyay, Rana de la Vega, Patricia Paik, Sun H. Murata, Yoko Ferguson, Earl W. Richie, Thomas L. Ooi, Guck T. TI Early Transcriptional Responses of HepG2-A16 Liver Cells to Infection by Plasmodium falciparum Sporozoites SO JOURNAL OF BIOLOGICAL CHEMISTRY LA English DT Article ID HUMAN HEPATOCELLULAR-CARCINOMA; CIRCUMSPOROZOITE PROTEIN; PROTECTIVE ANTIBODIES; GLYPICAN-3 EXPRESSION; INVITRO CULTURE; GENE-EXPRESSION; T-CELLS; MALARIA; STAGE; VIVAX AB Invasion of hepatocytes by Plasmodium sporozoites deposited by Anopheles mosquitoes, and their subsequent transformation into infective merozoites is an obligatory step in the initiation of malaria. Interactions between the sporozoites and hepatocytes lead to a distinct, complex and coordinated cellular and systemic host response. Little is known about host liver cell response to sporozoite invasion, or whether it is primarily adaptive for the parasite, for the host, or for both. Our present study used gene expression profiling of human HepG2-A16 liver cells infected with Plasmodium falciparum sporozoites to understand the host early cellular events and factors influencing parasite infectivity and sporozoite development. Our results show that as early as 30 min following wild-type, non-irradiated sporozoite exposure, the expressions of at least 742 genes was selectively altered. These genes regulate diverse biological functions, such as immune processes, cell adhesion and communications, metabolism pathways, cell cycle regulation, and signal transduction. These functions reflect cellular events consistent with initial host cell defense responses, as well as alterations in host cells to sustain sporozoites growth and survival. Irradiated sporozoites gave very similar gene expression pattern changes, but direct comparative analysis between liver gene expression profiles caused by irradiated and non-irradiated sporozoites identified 29 genes, including glypican-3, that were specifically up-regulated only in irradiated sporozoites. Elucidating the role of this subset of genes may help identify the molecular basis for the irradiated sporozoites inability to develop intrahepatically, and their usefulness as an immunogen for developing protective immunity against pre-erythrocytic stage malaria. C1 [Chattopadhyay, Rana; de la Vega, Patricia; Richie, Thomas L.] US Mil Malaria Vaccine Program, Malaria Program, Silver Spring, MD 20910 USA. [de la Vega, Patricia] Walter Reed Army Inst Res, Silver Spring, MD 20910 USA. [Richie, Thomas L.] USN, Med Res Ctr, Silver Spring, MD 20910 USA. [Paik, Sun H.; Murata, Yoko; Ferguson, Earl W.; Ooi, Guck T.] Sun BioMed Technol Inc, Ridgecrest, CA 93555 USA. RP Chattopadhyay, R (reprint author), US FDA, Div Vaccines & Related Prod Applicat, Off Vaccines Res & Review, Ctr Biol Evaluat & Res, Rockville, MD 20852 USA. EM rana.chattopadhyay@fda.hhs.gov; guckooi@sunbmt.com OI Richie, Thomas/0000-0002-2946-5456 FU Department of Defense [W81XWH-05-C-0030]; CRADA [LP-CRADA-NMRC-05-2107, 6000.RAD1.F.A0309] FX This work was supported by Department of Defense Small Business Innovative Research Grant W81XWH-05-C-0030 (to S. H. P., Y. M., E. W. F., and G. T. O.) and the work between Sun BioMedical Technologies and the Malaria Program, Naval Medical Research Center was conducted through a CRADA collaboration Grant LP-CRADA-NMRC-05-2107 and was supported by Grant 6000.RAD1.F.A0309 (to R. C., P. V., and T. L. R.). NR 64 TC 8 Z9 8 U1 0 U2 3 PU AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3996 USA SN 0021-9258 J9 J BIOL CHEM JI J. Biol. Chem. PD JUL 29 PY 2011 VL 286 IS 30 BP 26396 EP 26405 DI 10.1074/jbc.M111.240879 PG 10 WC Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA 796UK UT WOS:000293078200017 PM 21652718 ER PT J AU Daigle, A Modest, J Geiler, AL Gillette, S Chen, Y Geiler, M Hu, B Kim, S Stopher, K Vittoria, C Harris, VG AF Daigle, A. Modest, J. Geiler, A. L. Gillette, S. Chen, Y. Geiler, M. Hu, B. Kim, S. Stopher, K. Vittoria, C. Harris, V. G. TI Structure, morphology and magnetic properties of Mg(x)Zn(1-x)Fe2O4 ferrites prepared by polyol and aqueous co-precipitation methods: a low-toxicity alternative to Ni(x)Zn(1-x)Fe2O4 ferrites SO NANOTECHNOLOGY LA English DT Article ID ZN FERRITE; MGZN; TEMPERATURE AB The synthesis and properties of Mg(x)Zn(1-x)Fe2O4 spinel ferrites as a low-toxicity alternative to the technologically significant Ni(x)Zn(1-x)Fe2O4 ferrites are reported. Ferrite nanoparticles have been formed through both the polyol and aqueous co-precipitation methods that can be readily adapted to industrial scale synthesis to satisfy the demand of a variety of commercial applications. The structure, morphology and magnetic properties of Mg(x)Zn(1-x)Fe2O4 were studied as a function of composition and particle size. Scanning electron microscopy images show particles synthesised by the aqueous co-precipitation method possess a broad size distribution (i.e. similar to 80-120 nm) with an average diameter of the order of 100 nm +/- 20 nm and could be produced in high process yields of up to 25 g l(-1). In contrast, particles synthesised by the polyol-based co-precipitation method possess a narrower size distribution with an average diameter in the 30 nm +/- 5 nm range but are limited to smaller yields of similar to 6 g l(-1). Furthermore, the polyol synthesis method was shown to control average particle size by varying the length of the glycol surfactant chain. Particles prepared by both methods are compared with respect to their phase purity, crystal structure, morphology, magnetic properties and microwave properties. C1 [Daigle, A.; Modest, J.; Gillette, S.; Chen, Y.; Geiler, M.; Hu, B.; Kim, S.; Vittoria, C.; Harris, V. G.] Northeastern Univ, Dept Elect & Comp Engn, Ctr Microwave Magnet Mat & Integrated Circuits, Boston, MA 02115 USA. [Daigle, A.; Geiler, A. L.; Harris, V. G.] Metamagnetics Inc, Walpole, MA 02081 USA. [Stopher, K.] USN, Ctr Surface Warfare, Crane Div, Crane, IN 47522 USA. RP Daigle, A (reprint author), Northeastern Univ, Dept Elect & Comp Engn, Ctr Microwave Magnet Mat & Integrated Circuits, Boston, MA 02115 USA. EM daigle@metamagneticsinc.com NR 19 TC 19 Z9 19 U1 0 U2 18 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0957-4484 J9 NANOTECHNOLOGY JI Nanotechnology PD JUL 29 PY 2011 VL 22 IS 30 AR 305708 DI 10.1088/0957-4484/22/30/305708 PG 6 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied SC Science & Technology - Other Topics; Materials Science; Physics GA 788OW UT WOS:000292455300032 PM 21719975 ER PT J AU Poludnenko, AY Gardiner, TA Oran, ES AF Poludnenko, Alexei Y. Gardiner, Thomas A. Oran, Elaine S. TI Spontaneous Transition of Turbulent Flames to Detonations in Unconfined Media SO PHYSICAL REVIEW LETTERS LA English DT Article ID DEFLAGRATION; SUPERNOVAE; MHD; CHANNELS; GAS AB A deflagration-to-detonation transition (DDT) can occur in environments ranging from experimental and industrial systems to astrophysical thermonuclear (type Ia) supernovae explosions. Substantial progress has been made in explaining the nature of DDT in confined systems with walls, internal obstacles, or preexisting shocks. It remains unclear, however, whether DDT can occur in unconfined media. Here we use direct numerical simulations (DNS) to show that for high enough turbulent intensities unconfined, subsonic, premixed, turbulent flames are inherently unstable to DDT. The associated mechanism, based on the nonsteady evolution of flames faster than the Chapman-Jouguet deflagrations, is qualitatively different from the traditionally suggested spontaneous reaction-wave model. Critical turbulent flame speeds, predicted by this mechanism for the onset of DDT, are in agreement with DNS results. C1 [Poludnenko, Alexei Y.; Oran, Elaine S.] USN, Res Lab, Washington, DC 20375 USA. [Gardiner, Thomas A.] Sandia Natl Labs, Albuquerque, NM 87185 USA. RP Poludnenko, AY (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM apol@lcp.nrl.navy.mil FU AFOSR [F1ATA09114G005]; ONR/NRL FX We thank Vadim Gamezo, Craig Wheeler, and Forman Williams for valuable discussions. This work was supported by the AFOSR grant F1ATA09114G005 and by the ONR/NRL 6.1 Base Program. NR 26 TC 29 Z9 29 U1 0 U2 25 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0031-9007 EI 1079-7114 J9 PHYS REV LETT JI Phys. Rev. Lett. PD JUL 27 PY 2011 VL 107 IS 5 AR 054501 DI 10.1103/PhysRevLett.107.054501 PG 4 WC Physics, Multidisciplinary SC Physics GA 798DN UT WOS:000293182900008 PM 21867073 ER PT J AU Campo, JJ Whitman, TJ Freilich, D Burgess, TH Martin, GJ Doolan, DL AF Campo, Joseph J. Whitman, Timothy J. Freilich, Daniel Burgess, Timothy H. Martin, Gregory J. Doolan, Denise L. TI Toward a Surrogate Marker of Malaria Exposure: Modeling Longitudinal Antibody Measurements under Outbreak Conditions SO PLOS ONE LA English DT Article ID PLASMODIUM-FALCIPARUM ANTIGENS; LIVER-STAGE ANTIGEN-1; CIRCUMSPOROZOITE PROTEIN; RESPONSES; TRANSMISSION; AREA; REINFECTION; PREVALENCE; TRAVELERS; CHILDREN AB Background: Biomarkers of exposure to Plasmodium falciparum would be a useful tool for the assessment of malaria burden and analysis of intervention and epidemiological studies. Antibodies to pre-erythrocytic antigens represent potential surrogates of exposure. Methods and Findings: In an outbreak cohort of U.S. Marines deployed to Liberia, we modeled pre- and post-deployment IgG against P. falciparum sporozoites by immunofluorescence antibody test, and both IgG and IgM against the P. falciparum circumsporozoite protein by enzyme-linked immunosorbant assay. Modeling seroconversion thresholds by a fixed ratio, linear regression or nonlinear regression produced sensitivity for identification of exposed U.S. Marines between 58-70% and specificities between 87-97%, compared with malaria-naive U.S. volunteers. Exposure was predicted in 30-45% of the cohort. Conclusion: Each of the three models tested has merits in different studies, but further development and validation in endemic populations is required. Overall, these models provide support for an antibody-based surrogate marker of exposure to malaria. C1 [Campo, Joseph J.; Freilich, Daniel; Burgess, Timothy H.; Doolan, Denise L.] USN, Med Res Ctr, Silver Spring, MD 20910 USA. [Campo, Joseph J.] Univ Barcelona, Hosp Clin, CRESIB, Barcelona Ctr Int Hlth Res, Barcelona, Spain. [Whitman, Timothy J.; Burgess, Timothy H.; Martin, Gregory J.] Natl Naval Med Ctr, Dept Infect Dis, Bethesda, MD USA. [Doolan, Denise L.] Queensland Inst Med Res, Div Immunol, Brisbane, Qld 4006, Australia. [Doolan, Denise L.] Univ Queensland, Sch Med, Brisbane, Qld, Australia. RP Campo, JJ (reprint author), USN, Med Res Ctr, Silver Spring, MD 20910 USA. EM joe.campo@cresib.cat; Denise.Doolan@qimr.edu.au RI Doolan, Denise/F-1969-2015 FU US Army Medical Research and Materiel Command [6000.RAD1.F.A0309] FX This work was supported by funds allocated to the Naval Medical Research Center by the US Army Medical Research and Materiel Command (work unit 6000.RAD1.F.A0309). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. NR 24 TC 6 Z9 6 U1 0 U2 2 PU PUBLIC LIBRARY SCIENCE PI SAN FRANCISCO PA 185 BERRY ST, STE 1300, SAN FRANCISCO, CA 94107 USA SN 1932-6203 J9 PLOS ONE JI PLoS One PD JUL 27 PY 2011 VL 6 IS 7 AR e21826 DI 10.1371/journal.pone.0021826 PG 6 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA 799JJ UT WOS:000293282700010 PM 21818270 ER PT J AU Parks, AD Gray, JE AF Parks, A. D. Gray, J. E. TI Variance control in weak-value measurement pointers SO PHYSICAL REVIEW A LA English DT Article ID REALIZATION; SPIN AB The variance of an arbitrary pointer observable is considered for the general case that a complex weak value is measured using a complex valued pointer state. For the typical cases where the pointer observable is either its position or momentum, the associated expressions for the pointer's variance after the measurement contain a term proportional to the product of the weak value's imaginary part with the rate of change of the third central moment of position relative to the initial pointer state just prior to the time of the measurement interaction when position is the observable-or with the initial pointer state's third central moment of momentum when momentum is the observable. These terms provide a means for controlling pointer position and momentum variance and identify control conditions which, when satisfied, can yield variances that are smaller after the measurement than they were before the measurement. Measurement sensitivities which are useful for estimating weak-value measurement accuracies are also briefly discussed. C1 [Parks, A. D.; Gray, J. E.] USN, Ctr Surface Warfare, Electromagnet & Sensor Syst Dept, Dahlgren, VA 22448 USA. RP Parks, AD (reprint author), USN, Ctr Surface Warfare, Electromagnet & Sensor Syst Dept, Dahlgren, VA 22448 USA. FU Office of Naval Research FX This work was supported in part by a grant from the Naval Surface Warfare Center Dahlgren Division's In-House Laboratory Independent Research Program sponsored by the Office of Naval Research. NR 16 TC 15 Z9 15 U1 0 U2 3 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1050-2947 J9 PHYS REV A JI Phys. Rev. A PD JUL 25 PY 2011 VL 84 IS 1 AR 012116 DI 10.1103/PhysRevA.84.012116 PG 4 WC Optics; Physics, Atomic, Molecular & Chemical SC Optics; Physics GA 797KP UT WOS:000293126500007 ER PT J AU Mazin, II AF Mazin, I. I. TI Symmetry analysis of possible superconducting states in KxFeySe2 superconductors SO PHYSICAL REVIEW B LA English DT Article AB A newly discovered family of Fe-based superconductors is isostructural with the so-called 122 family of Fe pnictides but has a qualitatively different doping state. Early experiments indicate that superconductivity is nodeless, yet prerequisites for the s(+/-) nodeless state ( generally believed to be realized in Fe superconductors) are missing. It is tempting to assign a d-wave symmetry to the new materials, and it does seem, at first glance, that such a state may be nodeless. Yet a more careful analysis shows that it is not possible, given the particular 122 crystallography. If indeed superconductivity in this system is nodeless, the possible choice of admissible symmetries is severely limited: it is either a conventional single-sign s(+) state or another s(+/-) state, different from the one believed to be present in other Fe-based superconductors. C1 USN, Res Lab, Washington, DC 20375 USA. RP Mazin, II (reprint author), USN, Res Lab, Code 6393, Washington, DC 20375 USA. EM mazin@dave.nrl.navy.mil RI Mazin, Igor/B-6576-2008 NR 31 TC 66 Z9 66 U1 0 U2 13 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1098-0121 EI 1550-235X J9 PHYS REV B JI Phys. Rev. B PD JUL 25 PY 2011 VL 84 IS 2 AR 024529 DI 10.1103/PhysRevB.84.024529 PG 6 WC Physics, Condensed Matter SC Physics GA 797LD UT WOS:000293128300007 ER PT J AU Timmermans, ML Proshutinsky, A Krishfield, RA Perovich, DK Richter-Menge, JA Stanton, TP Toole, JM AF Timmermans, M-L. Proshutinsky, A. Krishfield, R. A. Perovich, D. K. Richter-Menge, J. A. Stanton, T. P. Toole, J. M. TI Surface freshening in the Arctic Ocean's Eurasian Basin: An apparent consequence of recent change in the wind-driven circulation SO JOURNAL OF GEOPHYSICAL RESEARCH-OCEANS LA English DT Article ID HEAT-FLUX; PACIFIC WATERS; CANADA BASIN; PACK ICE; SEA-ICE; VARIABILITY; HYDROGRAPHY; HALOCLINE; ATLANTIC; LAYER AB Data collected by an autonomous ice-based observatory that drifted into the Eurasian Basin between April and November 2010 indicate that the upper ocean was appreciably fresher than in 2007 and 2008. Sea ice and snowmelt over the course of the 2010 drift amounted to an input of less than 0.5 m of liquid freshwater to the ocean (comparable to the freshening by melting estimated for those previous years), while the observed change in upper-ocean salinity over the melt period implies a freshwater gain of about 0.7 m. Results of a wind-driven ocean model corroborate the observations of freshening and suggest that unusually fresh surface waters observed in parts of the Eurasian Basin in 2010 may have been due to the spreading of anomalously fresh water previously residing in the Beaufort Gyre. This flux is likely associated with a 2009 shift in the large-scale atmospheric circulation to a significant reduction in strength of the anticyclonic Beaufort Gyre and the Transpolar Drift Stream. C1 [Timmermans, M-L.] Yale Univ, Dept Geol & Geophys, New Haven, CT 06511 USA. [Proshutinsky, A.; Krishfield, R. A.; Toole, J. M.] Woods Hole Oceanog Inst, Dept Phys Oceanog, Woods Hole, MA 02543 USA. [Perovich, D. K.; Richter-Menge, J. A.] USA, Cold Reg Res & Engn Lab, Hanover, NH 03755 USA. [Stanton, T. P.] USN, Dept Oceanog, Postgrad Sch, Monterey, CA 93943 USA. RP Timmermans, ML (reprint author), Yale Univ, Dept Geol & Geophys, 210 Whitney Ave, New Haven, CT 06511 USA. EM mary-louise.timmermans@yale.edu RI Timmermans, Mary-Louise/N-5983-2014 FU National Science Foundation Office of Polar Programs Arctic Sciences Section [ARC-0519899, ARC-0856479, ARC-0806306] FX The instruments used in this study were deployed in collaboration with the North Pole Environmental Observatory (NPEO) from the Russian Barneo ice camps with logistic support provided by Andy Heiberg from the Polar Science Center (University of Washington) and Tom Quinn from CH2M Hill Polar Services. We appreciate the use of CTD data from the Freshwater Switchyard of the Arctic Ocean and the NPEO hydrographic surveys. The Ice-Tethered Profiler data were collected and made available by the Ice-Tethered Profiler Program based at the Woods Hole Oceanographic Institution (http://www.whoi.edu/itp). This work was funded by the National Science Foundation Office of Polar Programs Arctic Sciences Section under awards ARC-0519899, ARC-0856479, and ARC-0806306. Web cam images were provided by NOAA-PMEL. Ocean Data View software was used in this work (http://odv.awi.de/). NR 48 TC 41 Z9 41 U1 1 U2 26 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 0148-0227 J9 J GEOPHYS RES-OCEANS JI J. Geophys. Res.-Oceans PD JUL 23 PY 2011 VL 116 AR C00D03 DI 10.1029/2011JC006975 PG 17 WC Oceanography SC Oceanography GA 796YP UT WOS:000293089700002 ER PT J AU Lannoo, MJ Petersen, C Lovich, RE Nanjappa, P Phillips, C Mitchell, JC Macallister, I AF Lannoo, Michael J. Petersen, Christopher Lovich, Robert E. Nanjappa, Priya Phillips, Christopher Mitchell, Joseph C. Macallister, Irene TI Do Frogs Get Their Kicks on Route 66? Continental US Transect Reveals Spatial and Temporal Patterns of Batrachochytrium dendrobatidis Infection SO PLOS ONE LA English DT Article ID AMPHIBIAN CHYTRID FUNGUS; POPULATION DECLINES; RANA-CATESBEIANA; RAIN-FOREST; COSTA-RICA; SEASONAL-VARIATION; EMERGING PATHOGEN; AMERICAN BULLFROG; SURVEY PROTOCOL; MASS MORTALITY AB The chytrid fungus Batrachochytrium dendrobatidis (Bd) has been devastating amphibians globally. Two general scenarios have been proposed for the nature and spread of this pathogen: Bd is an epidemic, spreading as a wave and wiping out individuals, populations, and species in its path; and Bd is endemic, widespread throughout many geographic regions on every continent except Antarctica. To explore these hypotheses, we conducted a transcontinental transect of United States Department of Defense (DoD) installations along U. S. Highway 66 from California to central Illinois, and continuing eastward to the Atlantic Seaboard along U. S. Interstate 64 (in sum from Marine Corps Base Camp Pendleton in California to Naval Air Station Oceana in Virginia). We addressed the following questions: 1) Does Bd occur in amphibian populations on protected DoD environments? 2) Is there a temporal pattern to the presence of Bd? 3) Is there a spatial pattern to the presence of Bd? and 4) In these limited human-traffic areas, is Bd acting as an epidemic (i.e., with evidence of recent introduction and/or die-offs due to chytridiomycosis), or as an endemic (present without clinical signs of disease)? Bd was detected on 13 of the 15 bases sampled. Samples from 30 amphibian species were collected (10% of known United States' species); half (15) tested Bd positive. There was a strong temporal (seasonal) component; in total, 78.5% of all positive samples came in the first (spring/early-summer) sampling period. There was also a strong spatial component-the eleven temperate DoD installations had higher prevalences of Bd infection (20.8%) than the four arid (<60 mm annual precipitation) bases (8.5%). These data support the conclusion that Bd is now widespread, and promote the idea that Bd can today be considered endemic across much of North America, extending from coast-to-coast, with the exception of remote pockets of naive populations. C1 [Lannoo, Michael J.] Indiana Univ Sch Med, Terre Haute, IN USA. [Petersen, Christopher] USN, Facil Engn Command Atlantic, Norfolk, VA USA. [Lovich, Robert E.] USN, Facil Engn Command SW, San Diego, CA 92152 USA. [Nanjappa, Priya] Assoc Fish & Wildlife Agcy, Washington, DC USA. [Phillips, Christopher] Univ Illinois, Inst Nat Resource Sustainabil, Illinois Nat Hist Survey, Champaign, IL 61820 USA. [Mitchell, Joseph C.] Mitchell Ecol Res Serv, Gainesville, FL USA. [Macallister, Irene] USA, Corps Engineers, Construct Engn Res Lab, Champaign, IL USA. RP Lannoo, MJ (reprint author), Indiana Univ Sch Med, Terre Haute, IN USA. EM mlannoo@iupui.edu FU U.S. Department of Defense [09-426] FX Support for this project came from a U.S. Department of Defense Legacy grant (#09-426; https://www.dodlegacy.org.legacy/index.aspx). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. NR 101 TC 12 Z9 16 U1 4 U2 23 PU PUBLIC LIBRARY SCIENCE PI SAN FRANCISCO PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA SN 1932-6203 J9 PLOS ONE JI PLoS One PD JUL 21 PY 2011 VL 6 IS 7 AR e22211 DI 10.1371/journal.pone.0022211 PG 9 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA 795FA UT WOS:000292956800032 PM 21811576 ER PT J AU Kulp, JL Kulp, JL Pompliano, DL Guarnieri, F AF Kulp, John L., III Kulp, John L., Jr. Pompliano, David L. Guarnieri, Frank TI Diverse Fragment Clustering and Water Exclusion Identify Protein Hot Spots SO JOURNAL OF THE AMERICAN CHEMICAL SOCIETY LA English DT Article ID BINDING-SITES; LYSOZYME; SIMULATION; HYDRATION AB Simulated annealing of chemical potential located the highest affinity positions of eight organic probes and water on eight static structures of hen egg white lysozyme (HEWL) in various conformational states. In all HELW conformations, a diverse set of organic probes clustered in the known binding site (hot spot). Fragment clusters at other locations were excluded by tightly-bound waters so that only the hot-spot cluster remained in each case. The location of the hot spot was correctly predicted irrespective of the protein conformation and without accounting for protein flexibility during the simulations. Any one of the static structures could have been used to locate the hot spot. A site on a protein where a diversity of organic probes is calculated to cluster, but where water specifically does not bind, identifies a potential small-molecule binding site or protein-protein interaction hot spot. C1 [Kulp, John L., Jr.; Pompliano, David L.; Guarnieri, Frank] BioLeap Inc, Pennington, NJ 08534 USA. [Kulp, John L., III] USN, Res Lab, Div Chem, Washington, DC 20375 USA. [Guarnieri, Frank] Virginia Commonwealth Univ, Dept Physiol & Biophys, Richmond, VA 23298 USA. [Guarnieri, Frank] Boston Univ, Dept Biomed Engn, Boston, MA 02218 USA. RP Guarnieri, F (reprint author), BioLeap Inc, 238 W Delaware Ave, Pennington, NJ 08534 USA. EM frankguarnieri@yahoo.com FU Office of Naval Research FX We thank Ian Clouds dale and Rick Bryan for assistance and discussions. J.L.K. III acknowledges the Office of Naval Research for support. NR 17 TC 22 Z9 22 U1 0 U2 5 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0002-7863 J9 J AM CHEM SOC JI J. Am. Chem. Soc. PD JUL 20 PY 2011 VL 133 IS 28 BP 10740 EP 10743 DI 10.1021/ja203929x PG 4 WC Chemistry, Multidisciplinary SC Chemistry GA 797GT UT WOS:000293113200017 PM 21682273 ER PT J AU Abdo, AA Ackermann, M Ajello, M Allafort, A Ballet, J Barbiellini, G Bastieri, D Bechtol, K Bellazzini, R Berenji, B Blandford, RD Bonamente, E Borgland, AW Bregeon, J Brigida, M Bruel, P Buehler, R Buson, S Caliandro, GA Cameron, RA Camilo, F Caraveo, PA Cecchi, C Charles, E Chaty, S Chekhtman, A Chernyakova, M Cheung, CC Chiang, J Ciprini, S Claus, R Cohen-Tanugi, J Cominsky, LR Corbel, S Cutini, S D'Ammando, F de Angelis, A den Hartog, PR de Palma, F Dermer, CD Digel, SW Silva, EDE Dormody, M Drell, PS Drlica-Wagner, A Dubois, R Dubus, G Dumora, D Enoto, T Espinoza, CM Favuzzi, C Fegan, SJ Ferrara, EC Focke, WB Fortin, P Fukazawa, Y Funk, S Fusco, P Gargano, F Gasparrini, D Gehrels, N Germani, S Giglietto, N Giommi, P Giordano, F Giroletti, M Glanzman, T Godfrey, G Grenier, IA Grondin, MH Grove, JE Grundstrom, E Guiriec, S Gwon, C Hadasch, D Harding, AK Hayashida, M Hays, E Johannesson, G Johnson, AS Johnson, TJ Johnston, S Kamae, T Katagiri, H Kataoka, J Keith, M Kerr, M Knodlseder, J Kramer, M Kuss, M Lande, J Lee, SH Lemoine-Goumard, M Longo, F Loparco, F Lovellette, MN Lubrano, P Manchester, RN Marelli, M Mazziotta, MN Michelson, PF Mitthumsiri, W Mizuno, T Moiseev, AA Monte, C Monzani, ME Morselli, A Moskalenko, IV Murgia, S Nakamori, T Naumann-Godo, M Neronov, A Nolan, PL Norris, JP Noutsos, A Nuss, E Ohsugi, T Okumura, A Omodei, N Orlando, E Paneque, D Parent, D Pesce-Rollins, M Pierbattista, M Piron, F Porter, TA Possenti, A Raino, S Rando, R Ray, PS Razzano, M Razzaque, S Reimer, A Reimer, O Reposeur, T Ritz, S Sadrozinski, HFW Scargle, JD Sgro, C Shannon, R Siskind, EJ Smith, PD Spandre, G Spinelli, P Strickman, MS Suson, DJ Takahashi, H Tanaka, T Thayer, JG Thayer, JB Thompson, DJ Thorsett, SE Tibaldo, L Tibolla, O Torres, DF Tosti, G Troja, E Uchiyama, Y Usher, TL Vandenbroucke, J Vasileiou, V Vianello, G Vitale, V Waite, AP Wang, P Winer, BL Wolff, MT Wood, DL Wood, KS Yang, Z Ziegler, M Zimmer, S AF Abdo, A. A. Ackermann, M. Ajello, M. Allafort, A. Ballet, J. Barbiellini, G. Bastieri, D. Bechtol, K. Bellazzini, R. Berenji, B. Blandford, R. D. Bonamente, E. Borgland, A. W. Bregeon, J. Brigida, M. Bruel, P. Buehler, R. Buson, S. Caliandro, G. A. Cameron, R. A. Camilo, F. Caraveo, P. A. Cecchi, C. Charles, E. Chaty, S. Chekhtman, A. Chernyakova, M. Cheung, C. C. Chiang, J. Ciprini, S. Claus, R. Cohen-Tanugi, J. Cominsky, L. R. Corbel, S. Cutini, S. D'Ammando, F. de Angelis, A. den Hartog, P. R. de Palma, F. Dermer, C. D. Digel, S. W. do Couto e Silva, E. Dormody, M. Drell, P. S. Drlica-Wagner, A. Dubois, R. Dubus, G. Dumora, D. Enoto, T. Espinoza, C. M. Favuzzi, C. Fegan, S. J. Ferrara, E. C. Focke, W. B. Fortin, P. Fukazawa, Y. Funk, S. Fusco, P. Gargano, F. Gasparrini, D. Gehrels, N. Germani, S. Giglietto, N. Giommi, P. Giordano, F. Giroletti, M. Glanzman, T. Godfrey, G. Grenier, I. A. Grondin, M. -H. Grove, J. E. Grundstrom, E. Guiriec, S. Gwon, C. Hadasch, D. Harding, A. K. Hayashida, M. Hays, E. Johannesson, G. Johnson, A. S. Johnson, T. J. Johnston, S. Kamae, T. Katagiri, H. Kataoka, J. Keith, M. Kerr, M. Knodlseder, J. Kramer, M. Kuss, M. Lande, J. Lee, S. -H. Lemoine-Goumard, M. Longo, F. Loparco, F. Lovellette, M. N. Lubrano, P. Manchester, R. N. Marelli, M. Mazziotta, M. N. Michelson, P. F. Mitthumsiri, W. Mizuno, T. Moiseev, A. A. Monte, C. Monzani, M. E. Morselli, A. Moskalenko, I. V. Murgia, S. Nakamori, T. Naumann-Godo, M. Neronov, A. Nolan, P. L. Norris, J. P. Noutsos, A. Nuss, E. Ohsugi, T. Okumura, A. Omodei, N. Orlando, E. Paneque, D. Parent, D. Pesce-Rollins, M. Pierbattista, M. Piron, F. Porter, T. A. Possenti, A. Raino, S. Rando, R. Ray, P. S. Razzano, M. Razzaque, S. Reimer, A. Reimer, O. Reposeur, T. Ritz, S. Sadrozinski, H. F. -W. Scargle, J. D. Sgro, C. Shannon, R. Siskind, E. J. Smith, P. D. Spandre, G. Spinelli, P. Strickman, M. S. Suson, D. J. Takahashi, H. Tanaka, T. Thayer, J. G. Thayer, J. B. Thompson, D. J. Thorsett, S. E. Tibaldo, L. Tibolla, O. Torres, D. F. Tosti, G. Troja, E. Uchiyama, Y. Usher, T. L. Vandenbroucke, J. Vasileiou, V. Vianello, G. Vitale, V. Waite, A. P. Wang, P. Winer, B. L. Wolff, M. T. Wood, D. L. Wood, K. S. Yang, Z. Ziegler, M. Zimmer, S. TI DISCOVERY OF HIGH-ENERGY GAMMA-RAY EMISSION FROM THE BINARY SYSTEM PSR B1259-63/LS 2883 AROUND PERIASTRON WITH FERMI SO ASTROPHYSICAL JOURNAL LETTERS LA English DT Article DE binaries: eclipsing; gamma rays: stars; pulsars: individual (PSR B1259-63); X-rays: binaries ID PULSAR; RADIO; TELESCOPE; PASSAGE; PSR-B1259-63/SS2883; PSR-1259-63; RADIATION; CATALOG; WIND AB We report on the discovery of >= 100 MeV gamma-rays from the binary system PSR B1259-63/LS 2883 using the Large Area Telescope (LAT) on board Fermi. The system comprises a radio pulsar in orbit around a Be star. We report on LAT observations from near apastron to similar to 128 days after the time of periastron, t(p), on 2010 December 15. No gamma-ray emission was detected from this source when it was far from periastron. Faint gamma-ray emission appeared as the pulsar approached periastron. At similar to t(p) + 30 days, the >= 100 MeV gamma-ray flux increased over a period of a few days to a peak flux 20-30 times that seen during the pre-periastron period, but with a softer spectrum. For the following month, it was seen to be variable on daily timescales, but remained at similar to(1-4) x 10(-6) cm(-2) s(-1) before starting to fade at similar to t(p) + 57 days. The total gamma-ray luminosity observed during this period is comparable to the spin-down power of the pulsar. Simultaneous radio and X-ray observations of the source showed no corresponding dramatic changes in radio and X-ray flux between the pre-periastron and post-periastron flares. We discuss possible explanations for the observed gamma-ray-only flaring of the source. C1 [Ackermann, M.; Ajello, M.; Allafort, A.; Bechtol, K.; Berenji, B.; Blandford, R. D.; Borgland, A. W.; Buehler, R.; Cameron, R. A.; Charles, E.; Chiang, J.; Claus, R.; den Hartog, P. R.; Digel, S. W.; do Couto e Silva, E.; Drell, P. S.; Drlica-Wagner, A.; Dubois, R.; Enoto, T.; Funk, S.; Glanzman, T.; Godfrey, G.; Hayashida, M.; Johnson, A. S.; Kamae, T.; Kerr, M.; Lande, J.; Lee, S. -H.; Michelson, P. F.; Mitthumsiri, W.; Monzani, M. E.; Moskalenko, I. V.; Murgia, S.; Nolan, P. L.; Omodei, N.; Orlando, E.; Paneque, D.; Porter, T. A.; Reimer, A.; Reimer, O.; Tanaka, T.; Thayer, J. G.; Thayer, J. B.; Uchiyama, Y.; Usher, T. L.; Vandenbroucke, J.; Vianello, G.; Waite, A. P.; Wang, P.] Stanford Univ, Dept Phys, Kavli Inst Particle Astrophys & Cosmol, WW Hansen Expt Phys Lab, Stanford, CA 94305 USA. [Ackermann, M.; Ajello, M.; Allafort, A.; Bechtol, K.; Berenji, B.; Blandford, R. D.; Borgland, A. W.; Buehler, R.; Cameron, R. A.; Charles, E.; Chiang, J.; Claus, R.; den Hartog, P. R.; Digel, S. W.; do Couto e Silva, E.; Drell, P. S.; Drlica-Wagner, A.; Dubois, R.; Enoto, T.; Funk, S.; Glanzman, T.; Godfrey, G.; Hayashida, M.; Johnson, A. S.; Kamae, T.; Kerr, M.; Lande, J.; Lee, S. -H.; Michelson, P. F.; Mitthumsiri, W.; Monzani, M. E.; Moskalenko, I. V.; Murgia, S.; Nolan, P. L.; Omodei, N.; Orlando, E.; Paneque, D.; Porter, T. A.; Reimer, A.; Reimer, O.; Tanaka, T.; Thayer, J. G.; Thayer, J. B.; Uchiyama, Y.; Usher, T. L.; Vandenbroucke, J.; Vianello, G.; Waite, A. P.; Wang, P.] Stanford Univ, SLAC Natl Accelerator Lab, Stanford, CA 94305 USA. [Ballet, J.; Chaty, S.; Corbel, S.; Focke, W. B.; Grenier, I. A.; Naumann-Godo, M.; Pierbattista, M.; Tibaldo, L.] Univ Paris Diderot, CEA Saclay, Lab AIM, CEA,IRFU,CNRS,Serv Astrophys, F-91191 Gif Sur Yvette, France. [Barbiellini, G.; Longo, F.] Ist Nazl Fis Nucl, Sez Trieste, I-34127 Trieste, Italy. [Barbiellini, G.; Longo, F.] Univ Trieste, Dipartimento Fis, I-34127 Trieste, Italy. [Bastieri, D.; Buson, S.; Rando, R.; Tibaldo, L.] Ist Nazl Fis Nucl, Sez Padova, I-35131 Padua, Italy. [Bastieri, D.; Buson, S.; Rando, R.; Tibaldo, L.] Univ Padua, Dipartimento Fis G Galilei, I-35131 Padua, Italy. [Bellazzini, R.; Bregeon, J.; Kuss, M.; Pesce-Rollins, M.; Razzano, M.; Sgro, C.; Spandre, G.] Ist Nazl Fis Nucl, Sez Pisa, I-56127 Pisa, Italy. [Bonamente, E.; Cecchi, C.; Germani, S.; Lubrano, P.; Tosti, G.] Ist Nazl Fis Nucl, Sez Perugia, I-06123 Perugia, Italy. [Bonamente, E.; Cecchi, C.; Ciprini, S.; Germani, S.; Lubrano, P.; Tosti, G.] Univ Perugia, Dipartimento Fis, I-06123 Perugia, Italy. [Brigida, M.; de Palma, F.; Favuzzi, C.; Fusco, P.; Giglietto, N.; Giordano, F.; Loparco, F.; Monte, C.; Raino, S.; Spinelli, P.] Univ Politecn Bari, Dipartimento Fis M Merlin, I-70126 Bari, Italy. [Brigida, M.; de Palma, F.; Favuzzi, C.; Fusco, P.; Gargano, F.; Giglietto, N.; Giordano, F.; Loparco, F.; Mazziotta, M. N.; Monte, C.; Raino, S.; Spinelli, P.] Ist Nazl Fis Nucl, Sez Bari, I-70126 Bari, Italy. [Bruel, P.; Fegan, S. J.; Fortin, P.] Ecole Polytech, CNRS, IN2P3, Lab Leprince Ringuet, F-91128 Palaiseau, France. [Caliandro, G. A.; Hadasch, D.; Torres, D. F.] CSIC, IEEC, Inst Ciencias Espai, Barcelona 08193, Spain. [Camilo, F.] Columbia Univ, Columbia Astrophys Lab, New York, NY 10027 USA. [Caraveo, P. A.; Marelli, M.] INAF Ist Astrofis Spaziale & Fis Cosm, I-20133 Milan, Italy. [Chekhtman, A.] Artep Inc, Ellicott City, MD 21042 USA. [Chernyakova, M.] Dublin Inst Adv Studies, Sch Cosm Phys, Dublin 2, Ireland. [Cheung, C. C.] Natl Acad Sci, Natl Res Council Res Associate, Washington, DC 20001 USA. [Cohen-Tanugi, J.; Nuss, E.; Piron, F.; Vasileiou, V.] Univ Montpellier 2, CNRS, IN2P3, Lab Univers & Particules Montpellier, Montpellier, France. [Cominsky, L. R.] Sonoma State Univ, Dept Phys & Astron, Rohnert Pk, CA 94928 USA. [Corbel, S.] Inst Univ France, F-75005 Paris, France. [Cutini, S.; Gasparrini, D.; Giommi, P.] Agenzia Spaziale Italiana ASI Sci Data Ctr, I-00044 Rome, Italy. [D'Ammando, F.] IASF Palermo, I-90146 Palermo, Italy. [D'Ammando, F.] INAF Ist Astrofis Spaziale & Fis Cosm, I-00133 Rome, Italy. [de Angelis, A.] Univ Udine, Dipartimento Fis, I-33100 Udine, Italy. [de Angelis, A.] Ist Nazl Fis Nucl, Sez Trieste, Grp Collegato Udine, I-33100 Udine, Italy. [Abdo, A. A.; Dermer, C. D.; Grove, J. E.; Gwon, C.; Lovellette, M. N.; Ray, P. S.; Strickman, M. S.; Wolff, M. T.; Wood, D. L.; Wood, K. S.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. [Dormody, M.; Ritz, S.; Sadrozinski, H. F. -W.; Thorsett, S. E.; Ziegler, M.] Univ Calif Santa Cruz, Santa Cruz Inst Particle Phys, Dept Phys, Santa Cruz, CA 95064 USA. [Dormody, M.; Ritz, S.; Sadrozinski, H. F. -W.; Thorsett, S. E.; Ziegler, M.] Univ Calif Santa Cruz, Dept Astron & Astrophys, Santa Cruz, CA 95064 USA. [Dubus, G.] Univ Grenoble 1, Inst Planetol & Astrophys Grenoble, CNRS, INSU,UMR 5274, F-38041 Grenoble, France. [Dumora, D.; Lemoine-Goumard, M.; Reposeur, T.] Univ Bordeaux 1, Ctr Etud Nucl Bordeaux Gradignan, CNRS, IN2P3, F-33175 Gradignan, France. [Espinoza, C. M.; Kramer, M.] Univ Manchester, Sch Phys & Astron, Jodrell Bank, Ctr Astrophys, Manchester M13 9PL, Lancs, England. [Ferrara, E. C.; Gehrels, N.; Harding, A. K.; Hays, E.; Johnson, T. J.; Moiseev, A. A.; Thompson, D. J.; Troja, E.] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA. [Fukazawa, Y.; Katagiri, H.; Mizuno, T.] Hiroshima Univ, Dept Phys Sci, Hiroshima 7398526, Japan. [Giroletti, M.] INAF Ist Radioastron, I-40129 Bologna, Italy. [Grondin, M. -H.] Univ Tubingen, Inst Astron & Astrophys, D-72076 Tubingen, Germany. [Grundstrom, E.] Vanderbilt Univ, Dept Phys & Astron, Nashville, TN 37240 USA. [Guiriec, S.] Univ Alabama, Ctr Space Plasma & Aeron Res, Huntsville, AL 35899 USA. [Abdo, A. A.; Parent, D.; Razzaque, S.] George Mason Univ, Coll Sci, Ctr Earth Observing & Space Res, Fairfax, VA 22030 USA. [Johannesson, G.] Univ Iceland, Inst Sci, IS-107 Reykjavik, Iceland. [Johnson, T. J.; Moiseev, A. A.] Univ Maryland, Dept Phys, College Pk, MD 20742 USA. [Johnson, T. J.; Moiseev, A. A.] Univ Maryland, Dept Astron, College Pk, MD 20742 USA. [Johnston, S.; Keith, M.; Manchester, R. N.; Shannon, R.] CSIRO Astron & Space Sci, Australia Telescope Natl Facil, Epping, NSW 1710, Australia. [Kataoka, J.; Nakamori, T.] Waseda Univ, Res Inst Sci & Engn, Shinjuku Ku, Tokyo 1698555, Japan. [Knodlseder, J.] IRAP, CNRS, F-31028 Toulouse 4, France. [Knodlseder, J.] Univ Toulouse, UPS OMP, IRAP, GAHEC, Toulouse, France. [Kramer, M.; Noutsos, A.] Max Planck Inst Radioastron, D-53121 Bonn, Germany. [Moiseev, A. A.] CRESST, Greenbelt, MD 20771 USA. [Morselli, A.; Vitale, V.] Ist Nazl Fis Nucl, Sez Roma Tor Vergata, I-00133 Rome, Italy. [Neronov, A.] ISDC Data Ctr Astrophys, CH-1290 Versoix, Switzerland. [Norris, J. P.] Univ Denver, Dept Phys & Astron, Denver, CO 80208 USA. [Ohsugi, T.; Takahashi, H.] Hiroshima Univ, Hiroshima Astrophys Sci Ctr, Hiroshima 7398526, Japan. [Okumura, A.] JAXA, Inst Space & Astronaut Sci, Chuo Ku, Kanagawa 2525210, Japan. [Orlando, E.] Max Planck Inst Extraterr Phys, D-85748 Garching, Germany. [Paneque, D.] Max Planck Inst Phys & Astrophys, D-80805 Munich, Germany. [Possenti, A.] INAF Cagliari Astron Observ, I-09012 Capoterra, CA, Italy. [Reimer, A.; Reimer, O.] Leopold Franzens Univ Innsbruck, Inst Astro & Teilchenphys, A-6020 Innsbruck, Austria. [Reimer, A.; Reimer, O.] Leopold Franzens Univ Innsbruck, Inst Theoret Phys, A-6020 Innsbruck, Austria. [Scargle, J. D.] NASA, Ames Res Ctr, Div Space Sci, Moffett Field, CA 94035 USA. [Siskind, E. J.] NYCB Real Time Comp Inc, Lattingtown, NY 11560 USA. [Smith, P. D.; Winer, B. L.] Ohio State Univ, Dept Phys, Ctr Cosmol & Astroparticle Phys, Columbus, OH 43210 USA. [Suson, D. J.] Purdue Univ Calumet, Dept Chem & Phys, Hammond, IN 46323 USA. [Tibolla, O.] Univ Wurzburg, Inst Theoret Phys & Astrophys, D-97074 Wurzburg, Germany. [Torres, D. F.] ICREA, Barcelona, Spain. [Vianello, G.] CIFS, I-10133 Turin, Italy. [Vitale, V.] Univ Roma Tor Vergata, Dipartimento Fis, I-00133 Rome, Italy. [Yang, Z.; Zimmer, S.] Stockholm Univ, Dept Phys, SE-10691 Stockholm, Sweden. [Yang, Z.; Zimmer, S.] Oskar Klein Ctr Cosmoparticle Phys, SE-10691 Stockholm, Sweden. RP Abdo, AA (reprint author), USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. EM aous.abdo@nrl.navy.mil; Simon.Johnston@atnf.csiro.au; Andrii.Neronov@unige.ch; dmnparent@gmail.com; kent.wood@nrl.navy.mil RI Loparco, Francesco/O-8847-2015; Moskalenko, Igor/A-1301-2007; Mazziotta, Mario /O-8867-2015; Sgro, Carmelo/K-3395-2016; Torres, Diego/O-9422-2016; Orlando, E/R-5594-2016; Funk, Stefan/B-7629-2015; Morselli, Aldo/G-6769-2011; Gargano, Fabio/O-8934-2015; Johannesson, Gudlaugur/O-8741-2015; Thompson, David/D-2939-2012; Gehrels, Neil/D-2971-2012; Harding, Alice/D-3160-2012; lubrano, pasquale/F-7269-2012; Kuss, Michael/H-8959-2012; giglietto, nicola/I-8951-2012; Reimer, Olaf/A-3117-2013; Tosti, Gino/E-9976-2013; Rando, Riccardo/M-7179-2013; Hays, Elizabeth/D-3257-2012 OI Gasparrini, Dario/0000-0002-5064-9495; Ray, Paul/0000-0002-5297-5278; Marelli, Martino/0000-0002-8017-0338; Sgro', Carmelo/0000-0001-5676-6214; Rando, Riccardo/0000-0001-6992-818X; Bastieri, Denis/0000-0002-6954-8862; Omodei, Nicola/0000-0002-5448-7577; Chaty, Sylvain/0000-0002-5769-8601; Pesce-Rollins, Melissa/0000-0003-1790-8018; Giroletti, Marcello/0000-0002-8657-8852; Cutini, Sara/0000-0002-1271-2924; Loparco, Francesco/0000-0002-1173-5673; Moskalenko, Igor/0000-0001-6141-458X; Mazziotta, Mario /0000-0001-9325-4672; Torres, Diego/0000-0002-1522-9065; Grundstrom, Erika/0000-0002-5130-0260; Giordano, Francesco/0000-0002-8651-2394; Thorsett, Stephen/0000-0002-2025-9613; giommi, paolo/0000-0002-2265-5003; De Angelis, Alessandro/0000-0002-3288-2517; Shannon, Ryan/0000-0002-7285-6348; Caraveo, Patrizia/0000-0003-2478-8018; Funk, Stefan/0000-0002-2012-0080; Morselli, Aldo/0000-0002-7704-9553; Gargano, Fabio/0000-0002-5055-6395; Johannesson, Gudlaugur/0000-0003-1458-7036; Thompson, David/0000-0001-5217-9135; lubrano, pasquale/0000-0003-0221-4806; giglietto, nicola/0000-0002-9021-2888; Reimer, Olaf/0000-0001-6953-1385; FU European Community [ERC-StG-200911]; International Doctorate on Astroparticle Physics (IDAPP) program; NASA, United States; DOE, United States; CEA/Irfu, France; IN2P3/CNRS, France; ASI, Italy; INFN, Italy; MEXT, Japan; KEK, Japan; JAXA, Japan; K. A. Wallenberg Foundation; Swedish Research Council; National Space Board in Sweden; Commonwealth Government; NASA FX Funded by contract ERC-StG-200911 from the European Community.; Partially supported by the International Doctorate on Astroparticle Physics (IDAPP) program.; The Fermi-LAT Collaboration acknowledges support from a number of agencies and institutes for both the development and the operation of the LAT as well as scientific data analysis. These include NASA and DOE in the United States, CEA/Irfu and IN2P3/CNRS in France, ASI and INFN in Italy, MEXT, KEK, and JAXA in Japan, and the K. A. Wallenberg Foundation, the Swedish Research Council, and the National Space Board in Sweden. Additional support from INAF in Italy and CNES in France for science analysis during the operations phase is also gratefully acknowledged. The Parkes radio telescope is part of the Australia Telescope which is funded by the Commonwealth Government for operation as a National Facility managed by CSIRO. We thank our colleagues for their assistance with the radio timing observations. This work was supported in part by a NASA Fermi Guest Investigator Program. NR 28 TC 56 Z9 57 U1 2 U2 14 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 2041-8205 J9 ASTROPHYS J LETT JI Astrophys. J. Lett. PD JUL 20 PY 2011 VL 736 IS 1 AR L11 DI 10.1088/2041-8205/736/1/L11 PG 6 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 797OX UT WOS:000293138300011 ER PT J AU Barnes, E Economou, SE AF Barnes, Edwin Economou, Sophia E. TI Electron-Nuclear Dynamics in a Quantum Dot under Nonunitary Electron Control SO PHYSICAL REVIEW LETTERS LA English DT Article ID POLARIZATION AB We introduce a method for solving the problem of an externally controlled electron spin in a quantum dot interacting with host nuclei via the hyperfine interaction. Our method accounts for generalized (nonunitary) evolution effected by external controls and the environment, such as coherent lasers combined with spontaneous emission. As a concrete example, we develop the microscopic theory of the dynamics of nuclear-induced frequency focusing as first measured in Science 317, 1896 (2007); we find that the nuclear relaxation rates are several orders of magnitude faster than those quoted in that work. C1 [Barnes, Edwin] Univ Maryland, Dept Phys, Condensed Matter Theory Ctr, College Pk, MD 20742 USA. [Economou, Sophia E.] USN, Res Lab, Washington, DC 20375 USA. RP Barnes, E (reprint author), Univ Maryland, Dept Phys, Condensed Matter Theory Ctr, College Pk, MD 20742 USA. RI Barnes, Edwin/A-1583-2013 FU LPS/NSA FX This work was supported by LPS/NSA (E. B.) and in part by ONR and LPS/NSA (S. E. E.). S. E. E. acknowledges useful discussions on the Kraus formalism with A. Rajagopal. NR 22 TC 16 Z9 16 U1 0 U2 2 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0031-9007 J9 PHYS REV LETT JI Phys. Rev. Lett. PD JUL 20 PY 2011 VL 107 IS 4 AR 047601 DI 10.1103/PhysRevLett.107.047601 PG 4 WC Physics, Multidisciplinary SC Physics GA 794SR UT WOS:000292922100015 PM 21867043 ER PT J AU Trammell, SA Melde, BJ Zabetakis, D Deschamps, JR Dinderman, MA Johnson, BJ Kusterbeck, AW AF Trammell, Scott A. Melde, Brian J. Zabetakis, Daniel Deschamps, Jeffrey R. Dinderman, Michael A. Johnson, Brandy J. Kusterbeck, Anne W. TI Electrochemical detection of TNT with in-line pre-concentration using imprinted diethylbenzene-bridged periodic mesoporous organosilicas SO SENSORS AND ACTUATORS B-CHEMICAL LA English DT Article DE Square wave voltammetry; Pre-concentration; Periodic mesoporous organosilicas; 2,4,6-Trinitrotoluene (TNT) ID SOLID-PHASE MICROEXTRACTION; AMPEROMETRIC DETECTION; LIQUID-CHROMATOGRAPHY; NANOPOROUS ORGANOSILICAS; VOLTAMMETRIC DETECTION; SILICA NANOPARTICLES; EXPLOSIVE COMPOUNDS; AQUEOUS SAMPLES; ORGANIC GROUPS; 2,4,6-TRINITROTOLUENE AB We examined the adsorption and release of TNT using diethylbenzene-bridged (DEB) periodic mesoporous organosilica sorbents under varying conditions. The sorbents were applied for in-line target pre-concentration in conjunction with an electrochemical flow cell containing a glassy carbon electrode. Square wave voltammetry was employed for TNT detection. TNT sample volumes between 2 and 480 mL at concentrations ranging from 0.5 to 500 ppb were passed through the DEB sorbents (imprinted or not imprinted for TNT) at pH 6 (sodium acetate) or at pH 7.4 (PBS). Release of target was accomplished using solvent mixtures of methanol/water with sodium acetate as electrolyte or acetonitrile/water with PBS components as electrolyte. Under these conditions, the TNT was released in <200 mu L of the solvent mixture, and pre-concentration factors of >3000 can be achieved when using large volumes of trace TNT samples. When sample volumes of 2 m L were utilized, the sensing system gave a linear response between 20 and 500 ppb with an estimated limit of detection of 13 ppb. When pre-concentrating 480 mL of sample in either buffered solution or seawater, detection of 0.5 ppb TNT was achieved with a signal to noise ratio of 20. Published by Elsevier B.V. C1 [Trammell, Scott A.; Melde, Brian J.; Zabetakis, Daniel; Deschamps, Jeffrey R.; Dinderman, Michael A.; Johnson, Brandy J.; Kusterbeck, Anne W.] USN, Ctr Bio Mol Sci & Engn, Res Lab, Washington, DC 20375 USA. RP Trammell, SA (reprint author), USN, Ctr Bio Mol Sci & Engn, Res Lab, Code 6900, Washington, DC 20375 USA. EM scott.trammell@nrl.navy.mil RI Johnson, Brandy/B-3462-2008; OI Johnson, Brandy/0000-0002-3637-0631; Deschamps, Jeffrey/0000-0001-5845-0010 FU NRL/Office of Naval Research; US Strategic Environmental Research and Development Program (SERDP) [ER-1604] FX The authors wish to thank Kim Edward for his technical help through the Science and Engineering Apprentice Program at NRL. This work was funded by the NRL/Office of Naval Research and the US Strategic Environmental Research and Development Program (SERDP, ER-1604). NR 48 TC 19 Z9 19 U1 0 U2 20 PU ELSEVIER SCIENCE SA PI LAUSANNE PA PO BOX 564, 1001 LAUSANNE, SWITZERLAND SN 0925-4005 J9 SENSOR ACTUAT B-CHEM JI Sens. Actuator B-Chem. PD JUL 20 PY 2011 VL 155 IS 2 BP 737 EP 744 DI 10.1016/j.snb.2011.01.039 PG 8 WC Chemistry, Analytical; Electrochemistry; Instruments & Instrumentation SC Chemistry; Electrochemistry; Instruments & Instrumentation GA 779JO UT WOS:000291774100043 ER PT J AU Wang, DW Wijesekera, HW Teague, WJ Rogers, WE Jarosz, E AF Wang, D. W. Wijesekera, H. W. Teague, W. J. Rogers, W. E. Jarosz, E. TI Bubble cloud depth under a hurricane SO GEOPHYSICAL RESEARCH LETTERS LA English DT Article ID EXTREME WIND SPEEDS; TROPICAL CYCLONES; OCEAN; FREQUENCY; EXCHANGE; WAVES; IVAN AB The bubble cloud depth and its correlation with extreme winds are key elements of bubble-mediated gas injection, which are critical to the determination of the global gas budgets. The characteristics of bubble cloud depth were examined from measurements collected during the passage of a category-4 hurricane with winds up to 50 m s(-1). The bubble cloud depth increases linearly with wind speed for winds less than 35 m s(-1). Our findings are consistent with previous observations at low to moderate wind speeds. However, the rate of increase is reduced significantly at winds higher than 35 m s(-1). Citation: Wang, D.W., H.W. Wijesekera, W.J. Teague, W.E. Rogers, and E. Jarosz (2011), Bubble cloud depth under a hurricane, Geophys. Res. Lett., 38, L14604, doi: 10.1029/2011GL047966. C1 [Wang, D. W.; Wijesekera, H. W.; Teague, W. J.; Rogers, W. E.; Jarosz, E.] USN, Res Lab, Stennis Space Ctr, MS 39529 USA. RP Wang, DW (reprint author), USN, Res Lab, Bldg 1009, Stennis Space Ctr, MS 39529 USA. EM dwang@nrlssc.navy.mil FU Office of Naval Research [0601153N] FX This work is supported by the Office of Naval Research as part of the NRL's basic research project SEED under program element grant 0601153N. We gratefully acknowledge the many constructive comments made by two reviewers. We thank Mr. Idle and Mr. Rivalan at Teledyne RD Instruments for their helpful discussion of the acoustic backscattering measurements. NR 16 TC 5 Z9 5 U1 0 U2 3 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 0094-8276 J9 GEOPHYS RES LETT JI Geophys. Res. Lett. PD JUL 19 PY 2011 VL 38 AR L14604 DI 10.1029/2011GL047966 PG 4 WC Geosciences, Multidisciplinary SC Geology GA 797MF UT WOS:000293131300002 ER PT J AU Pons, T Medintz, IL Farrell, D Wang, X Grimes, AF English, DS Berti, L Mattoussi, H AF Pons, Thomas Medintz, Igor L. Farrell, Dorothy Wang, Xiang Grimes, Amy F. English, Douglas S. Berti, Lorenzo Mattoussi, Hedi TI Single-Molecule Colocalization Studies Shed Light on the Idea of Fully Emitting versus Dark Single Quantum Dots SO SMALL LA English DT Article ID CDSE NANOCRYSTALS; FLUORESCENCE INTERMITTENCY; ENERGY-TRANSFER; BLINKING; PROTEINS; KINETICS AB In this report the correlation between the solution photoluminescence (PL) quantum yield and the fluorescence emission of individual semiconductor quantum dots (QDs) is investigated. This is done by taking advantage of previously reported enhancement in the macroscopic quantum yield of water-soluble QDs capped with dihydrolipoic acid (DHLA) when self-assembled with polyhistidine-appended proteins, and by using fluorescence coincidence analysis (FCA) to detect the presence of "bright" and "dark" single QDs in solution. This allows for changes in the fraction of the two QD species to be tracked as the PL yield of the solution is progressively altered. The results clearly indicate that in a dispersion of luminescent nanocrystals, "bright" (intermittently emitting) single QDs coexist with "permanently dark" (non-emitting) QDs. Furthermore, the increase in the fraction of emitting QDs accompanies the increase in the PL quantum yield of the solution. These findings support the idea that a dispersion of QDs consists of two optically distinct populations of nanocrystals-one is "bright" while the other is "dark;" and that the relative fraction of these two populations defines the overall PL yield. C1 [Pons, Thomas; Medintz, Igor L.; Farrell, Dorothy; Mattoussi, Hedi] USN, Res Lab, Div Opt Sci, Washington, DC 20375 USA. [Wang, Xiang; Grimes, Amy F.; English, Douglas S.] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA. [Berti, Lorenzo] Univ Calif, Dept Biochem & Mol Med, Davis Sch Med, Sacramento, CA 95817 USA. RP Mattoussi, H (reprint author), Florida State Univ, Dept Chem & Biochem, Tallahassee, FL 32306 USA. EM mattoussi@chem.fsu.edu RI Pons, Thomas/A-8667-2008 OI Pons, Thomas/0000-0001-8800-4302 FU NRL; ONR; DTRA; NRC FX The authors acknowledge NRL, ONR, and DTRA for financial support. DF acknowledges the NRC postdoctoral fellowship. NR 33 TC 13 Z9 13 U1 2 U2 18 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1613-6810 J9 SMALL JI Small PD JUL 18 PY 2011 VL 7 IS 14 SI SI BP 2101 EP 2108 DI 10.1002/smll.201100802 PG 8 WC Chemistry, Multidisciplinary; Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter SC Chemistry; Science & Technology - Other Topics; Materials Science; Physics GA 804EH UT WOS:000293636600034 PM 21710484 ER PT J AU Zhang, JL Campbell, JR Reid, JS Westphal, DL Baker, NL Campbell, WF Hyer, EJ AF Zhang, Jianglong Campbell, James R. Reid, Jeffrey S. Westphal, Douglas L. Baker, Nancy L. Campbell, William F. Hyer, Edward J. TI Evaluating the impact of assimilating CALIOP-derived aerosol extinction profiles on a global mass transport model SO GEOPHYSICAL RESEARCH LETTERS LA English DT Article ID SAHARAN DUST; MODIS; RETRIEVALS; LIDAR; PRODUCTS; AERONET; PRIDE; CLOUD AB Coupled two/three-dimensional variational (2D/3DVAR) assimilation of aerosol physical properties retrieved from the Moderate Resolution Imaging Spectroradiometer (MODIS), Multi-angle Imaging Spectroradiometer (MISR) and Cloud Aerosol Lidar with Orthogonal Polarization (CALIOP) satellite-borne instruments is described for the U. S. Navy Aerosol Analysis and Prediction System (NAAPS) global aerosol mass transport model. Coupled 2D/3DVAR assimilation for NAAPS is evaluated for 48-hr forecast cycles, computed four times daily in six-hour intervals, versus stand-alone 2DVAR assimilation of MODIS and MISR aerosol optical depths (AOD). Both systems are validated against AERONET ground-based sun photometer measurements of AOD. Despite a narrow nadir viewing swath and more than 2700 km of equatorial separation between orbits, satellite lidar data assimilation elicits a positive model response. Improvements in analysis and forecast AOD absolute errors are found over both land and maritime AERONET sites. The primary impact to the model from 3DVAR assimilation is the redistribution of aerosol mass into the boundary layer, though the process is sensitive to parameterization of vertical error correlation lengths. Citation: Zhang, J., J. R. Campbell, J. S. Reid, D. L. Westphal, N. L. Baker, W. F. Campbell, and E. J. Hyer (2011), Evaluating the impact of assimilating CALIOP-derived aerosol extinction profiles on a global mass transport model, Geophys. Res. Lett., 38, L14801, doi:10.1029/2011GL047737. C1 [Zhang, Jianglong] Univ N Dakota, Dept Atmospher Sci, Grand Forks, ND 58202 USA. [Campbell, James R.; Reid, Jeffrey S.; Westphal, Douglas L.; Baker, Nancy L.; Campbell, William F.; Hyer, Edward J.] USN, Marine Meteorol Div, Res Lab, Monterey, CA 93943 USA. RP Zhang, JL (reprint author), Univ N Dakota, Dept Atmospher Sci, 2901 Univ Ave,Stop 8264, Grand Forks, ND 58202 USA. EM jzhang@atmos.und.edu RI Hyer, Edward/E-7734-2011; Campbell, James/C-4884-2012; Reid, Jeffrey/B-7633-2014 OI Hyer, Edward/0000-0001-8636-2026; Campbell, James/0000-0003-0251-4550; Reid, Jeffrey/0000-0002-5147-7955 FU Office of Naval Research [32]; NASA; NASA, CALIPSO Science Team [NNH07AG44I] FX This research was funded by the Office of Naval Research Code 32, the Office of Naval Research Young Investigator Program, and the NASA Interdisciplinary Science Program. Authors J.R.C. and J.S.R. acknowledge NASA grant NNH07AG44I as part of the CALIPSO Science Team. The group acknowledges the AERONET program, their contributing principal investigators and their staff for coordinating the coastal and inland sites used in this investigation. NR 34 TC 26 Z9 26 U1 1 U2 12 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 0094-8276 J9 GEOPHYS RES LETT JI Geophys. Res. Lett. PD JUL 16 PY 2011 VL 38 AR L14801 DI 10.1029/2011GL047737 PG 6 WC Geosciences, Multidisciplinary SC Geology GA 793PH UT WOS:000292835100004 ER PT J AU Hashemi, N Erickson, JS Golden, JP Jackson, KM Ligler, FS AF Hashemi, Nastaran Erickson, Jeffrey S. Golden, Joel P. Jackson, Kirsten M. Ligler, Frances S. TI Microflow Cytometer for optical analysis of phytoplankton SO BIOSENSORS & BIOELECTRONICS LA English DT Article DE Flow cytometry; Microfluidics; Optical sensing; Hydrodynamic focusing; Phytoplankton ID FLOW-CYTOMETRY; AIRBORNE LIDAR; OCEAN; DISCRIMINATION; FLUORESCENCE; VARIABILITY; INDICATORS; RETRIEVAL; TOXINS AB Analysis of the intrinsic fluorescence profiles of individual marine algae can be used in general classification of organisms based on cell size and fluorescence properties. We describe the design and fabrication of a Microflow Cytometer on a chip for characterization of phytoplankton. The Microflow Cytometer measured distinct side scatter and fluorescence properties of Synechococcus sp., Nitzschia d., and Thalassiosira p.; measurements were confirmed using the benchtop Accuri C6 flow cytometer. The Microflow Cytometer proved sensitive enough to detect and characterize picoplankton with diameter approximately 1 mu m and larger phytoplankton of up to 80 mu m in length. The wide range in size discrimination coupled with detection of intrinsic fluorescent pigments suggests that this Microflow Cytometer will be able to distinguish different populations of phytoplankton on unmanned underwater vehicles. Published by Elsevier B.V. C1 [Hashemi, Nastaran; Erickson, Jeffrey S.; Golden, Joel P.; Jackson, Kirsten M.; Ligler, Frances S.] USN, Res Lab, Ctr Biomol Sci & Engn, Washington, DC 20375 USA. RP Ligler, FS (reprint author), USN, Res Lab, Ctr Biomol Sci & Engn, Washington, DC 20375 USA. EM Frances.ligler@nrl.navy.mil RI Erickson, Jeffrey/F-6273-2011; Hashemi, Nastaran/A-7645-2012 OI Hashemi, Nastaran/0000-0001-8921-7588 FU ONR/NRL [69-6339] FX This work was supported by ONR/NRL 6.2 work unit 69-6339. Nastaran Hashemi is an American Society for Engineering Education (ASEE) Postdoctoral Fellow. Kirsten Jackson was a Navy Research Enterprise Internship Program summer fellow. The authors thank Dr. Alan Weidemann (Naval Research Laboratory, Stennis, MI) and Dr. Lisa Hilliard (National Oceanic and Atmospheric Administration, Charleston, SC) for their assistance with this project. The views expressed here are those of the authors and do not represent opinion or policy of the US Navy or Department of Defense. NR 30 TC 39 Z9 40 U1 3 U2 51 PU ELSEVIER ADVANCED TECHNOLOGY PI OXFORD PA OXFORD FULFILLMENT CENTRE THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0956-5663 J9 BIOSENS BIOELECTRON JI Biosens. Bioelectron. PD JUL 15 PY 2011 VL 26 IS 11 BP 4263 EP 4269 DI 10.1016/j.bios.2011.03.042 PG 7 WC Biophysics; Biotechnology & Applied Microbiology; Chemistry, Analytical; Electrochemistry; Nanoscience & Nanotechnology SC Biophysics; Biotechnology & Applied Microbiology; Chemistry; Electrochemistry; Science & Technology - Other Topics GA 797DG UT WOS:000293104100001 PM 21601442 ER PT J AU Myers, CA Faix, DJ Blair, PJ AF Myers, Christopher A. Faix, Dennis J. Blair, Patrick J. TI Possible Reduced Effectiveness of the 2009 H1N1 Component of Live, Attenuated Influenza Vaccine SO CLINICAL INFECTIOUS DISEASES LA English DT Letter C1 [Faix, Dennis J.] USN, Febrile Resp Illness Surveillance Team, Febrile Resp Illness Surveillance Grp, Dept Resp Dis Res,Hlth Res Ctr, San Diego, CA 92106 USA. RP Faix, DJ (reprint author), USN, Febrile Resp Illness Surveillance Team, Febrile Resp Illness Surveillance Grp, Dept Resp Dis Res,Hlth Res Ctr, 140 Sylvester Rd, San Diego, CA 92106 USA. EM dennis.faix@med.navy.mil RI Valle, Ruben/A-7512-2013 NR 4 TC 5 Z9 5 U1 0 U2 2 PU OXFORD UNIV PRESS INC PI CARY PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA SN 1058-4838 J9 CLIN INFECT DIS JI Clin. Infect. Dis. PD JUL 15 PY 2011 VL 53 IS 2 BP 207 EP 208 DI 10.1093/cid/cir282 PG 2 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA 796BA UT WOS:000293024000016 PM 21690631 ER PT J AU Hebert, CG Terray, A Hart, SJ AF Hebert, Colin G. Terray, Alex Hart, Sean J. TI Toward Label-Free Optical Fractionation of Blood-Optical Force Measurements of Blood Cells SO ANALYTICAL CHEMISTRY LA English DT Article ID DIFFERENTIATION; CHROMATOGRAPHY; MANIPULATION; PARTICLES; DISCOVERY; CYTOMETRY; HL-60; BEAM; CHIP; LINE AB There is a compelling need to develop systems capable of processing blood and other particle streams for detection of pathogens that are sensitive, selective, automated, and cost/size effective. Our research seeks to develop laser-based separations that do not rely on prior knowledge, antibodies, or fluorescent molecules for pathogen detection. Rather, we aim to harness inherent differences in optical pressure, which arise from variations in particle size, shape, refractive index, or morphology, as a means of separating and characterizing particles. Our method for measuring optical pressure involves focusing a laser into a fluid flowing opposite to the direction of laser propagation. As microscopic particles in the flow path encounter the beam, they are trapped axially along the beam and are pushed upstream from the laser focal point to rest at a point where the optical and fluid forces on the particle balance. On the basis of the flow rate at which this balance occurs, the optical pressure felt by the particle can be calculated. As a first step in the development of a label-free device for processing blood, a system has been developed to measure optical pressure differences between the components of human blood, including erythrocytes, monocytes, granulocytes, and lymphocytes. Force differentials have been measured between various components, indicating the potential for laser-based separation of blood components based upon differences in optical pressure. Potential future applications include the early detection of blood-borne pathogens for the prevention of sepsis and other diseases as well as the detection of biological threat agents. C1 [Hebert, Colin G.; Terray, Alex; Hart, Sean J.] USN, Div Chem, Bio Analyt Chem Sect, Res Lab, Washington, DC 20375 USA. RP Hart, SJ (reprint author), USN, Div Chem, Bio Analyt Chem Sect, Res Lab, Code 6112 4555,Overlook Ave SW, Washington, DC 20375 USA. EM sean.hart@nrl.navy.mil FU U.S. Naval Research Laboratory; Defense Threat Reduction Agency (DTRA) [BA09DET067]; Naval Research Laboratory (NRL) FX This research was performed while the author (C.G.H.) held a National Research Council Research Associateship Award at the U.S. Naval Research Laboratory. Funding was provided by the Defense Threat Reduction Agency (DTRA), under contract number BA09DET067, and the Naval Research Laboratory (NRL). NR 39 TC 17 Z9 17 U1 1 U2 22 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0003-2700 EI 1520-6882 J9 ANAL CHEM JI Anal. Chem. PD JUL 15 PY 2011 VL 83 IS 14 BP 5666 EP 5672 DI 10.1021/ac200834u PG 7 WC Chemistry, Analytical SC Chemistry GA 794JN UT WOS:000292892000027 PM 21634802 ER PT J AU McInturf, SM Bekkedal, MYV Wilfong, E Arfsten, D Chapman, G Gunasekar, PG AF McInturf, S. M. Bekkedal, M. Y. V. Wilfong, E. Arfsten, D. Chapman, G. Gunasekar, P. G. TI The potential reproductive, neurobehavioral and systemic effects of soluble sodium tungstate exposure in Sprague-Dawley rats SO TOXICOLOGY AND APPLIED PHARMACOLOGY LA English DT Article DE Tungstate; Health effects; Reproduction; Behavioral study; Rat; Toxicity ID COPPER AB The debate on tungsten (W) is fostered by its continuous usage in military munitions. Reports demonstrate W solubilizes in soil and can migrate into drinking water supplies and, therefore, is a potential health risk to humans. This study evaluated the reproductive, systemic and neurobehavioral effects of sodium tungstate (NaW) in rats following 70 days of daily pre-and postnatal exposure via oral gavage to 5, 62.5 and 125 mg/kg/day of NaW through mating, gestation and weaning (PND 0-20). Daily administration of NaW produced no overt evidence of toxicity and had no apparent effect on mating success or offspring physical development. Distress vocalizations were elevated in F(1) offspring from the high dose group, whereas righting reflex showed unexpected sex differences where males demonstrated faster righting than females; however, the effects were not dose-dependent. Locomotor activity was affected in both low and high-dose groups of F(1) females. Low-dose group showed increased distance traveled, more time in ambulatory movements and less time in stereotypic behavior than controls or high dose animals. The high-dose group had more time in stereotypical movements than controls, and less time resting than controls and the lowest exposure group. Maternal retrieval was not affected by NaW exposure. Tungsten analysis showed a systemic distribution of NaW in both parents and offspring, with preferential uptake within the immune organs, including the femur, spleen and thymus. Histopathological evidence suggested no severe chronic injury or loss of function in these organs. However, the heart showed histological lesions, histiocytic inflammation from minimal to mild with cardiomyocyte degeneration and necrosis in several P(0) animals of 125 mg NaW dose group. The result of this study suggests that pre and postnatal exposure to NaW may produce subtle neurobehavioral effects in offspring related to motor activity and emotionality. Published by Elsevier Inc. C1 [McInturf, S. M.; Chapman, G.; Gunasekar, P. G.] Naval Med Res Unit Dayton NAMRU, Wright Patterson AFB, OH USA. [Bekkedal, M. Y. V.] Two Steps Forward LLC, Sun Prairie, WI USA. [Wilfong, E.] USN Acad, Annapolis, MD USA. [Arfsten, D.] Naval Air Stn, Navy Drug Screening Lab, Jacksonville, FL USA. RP Gunasekar, PG (reprint author), Naval Med Res Unit Dayton NAMRU, Wright Patterson AFB, OH USA. EM palur.gunasekar@wpafb.af.mil FU Defense Health Programs (DHP) reimbursable Work Unit [60768] FX This work was supported by Defense Health Programs (DHP) reimbursable Work Unit # 60768. The animals used in this study were handled in accordance with the principles stated in the Guide for the Care and Use of Laboratory Animals, National Research Council, 1996, and the Animal Welfare Act of 1996, as amended. The authors gratefully acknowledge support from vivarium, WPAFB for animal facility. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect those of the Defense Health Program. NR 17 TC 12 Z9 12 U1 2 U2 7 PU ACADEMIC PRESS INC ELSEVIER SCIENCE PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA SN 0041-008X J9 TOXICOL APPL PHARM JI Toxicol. Appl. Pharmacol. PD JUL 15 PY 2011 VL 254 IS 2 SI SI BP 133 EP 137 DI 10.1016/j.taap.2010.04.021 PG 5 WC Pharmacology & Pharmacy; Toxicology SC Pharmacology & Pharmacy; Toxicology GA 793HJ UT WOS:000292810700006 PM 21296100 ER PT J AU Gunasekar, PG Stanek, LW AF Gunasekar, Palur G. Stanek, Lindsay W. TI Advances in exposure and toxicity assessment of particulate matter: An overview of presentations at the 2009 Toxicology and Risk Assessment Conference SO TOXICOLOGY AND APPLIED PHARMACOLOGY LA English DT Article DE Particulate matter; Tungsten alloys; Middle East dust; Aerosol collection; Epidemiology; Health effect AB The 2009 Toxicology and Risk Assessment Conference (TRAC) session on "Advances in Exposure and Toxicity Assessment of Particulate Matter" was held in April 2009 in West Chester, OH. The goal of this session was to bring together toxicology, geology and risk assessment experts from the Department of Defense and academia to examine issues in exposure assessment and report on recent epidemiological findings of health effects associated with particulate matter (PM) exposure. Important aspects of PM exposure research are to detect and monitor low levels of PM with various chemical compositions and to assess the health risks associated with these exposures. As part of the overall theme, some presenters discussed collection methods for sand and dust from Iraqi and Afghanistan regions, health issues among deployed personnel, and future directions for risk assessment research among these populations. The remaining speakers focused on the toxicity of ultrafine PM and the characterization of aerosols generated during ballistic impacts of tungsten heavy alloys. Published by Elsevier Inc. C1 [Gunasekar, Palur G.] Naval Hlth Res Ctr Detachment, Environm Hlth Effects Lab, Wright Patterson AFB, Dayton, OH USA. [Stanek, Lindsay W.] US EPA, Natl Ctr Environm Assessment, Res Triangle Pk, NC 27711 USA. RP Gunasekar, PG (reprint author), Naval Hlth Res Ctr Detachment, Environm Hlth Effects Lab, Wright Patterson AFB, Dayton, OH USA. EM palur.gunasekar@wpafb.af.mil; Stanek.Lindsay@epa.gov NR 4 TC 3 Z9 3 U1 2 U2 14 PU ACADEMIC PRESS INC ELSEVIER SCIENCE PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA SN 0041-008X J9 TOXICOL APPL PHARM JI Toxicol. Appl. Pharmacol. PD JUL 15 PY 2011 VL 254 IS 2 SI SI BP 141 EP 144 DI 10.1016/j.taap.2010.10.020 PG 4 WC Pharmacology & Pharmacy; Toxicology SC Pharmacology & Pharmacy; Toxicology GA 793HJ UT WOS:000292810700008 PM 21034760 ER PT J AU Russ, AH Schweidenback, L Yasar, M Li, CH Hanbicki, AT Korkusinski, M Kioseoglou, G Jonker, BT Petrou, A AF Russ, A. H. Schweidenback, L. Yasar, M. Li, C. H. Hanbicki, A. T. Korkusinski, M. Kioseoglou, G. Jonker, B. T. Petrou, A. TI Spin-polarized multiexcitons in quantum dots in the presence of spin-orbit interaction SO PHYSICAL REVIEW B LA English DT Article ID LIGHT-EMITTING-DIODES; INJECTION; SEMICONDUCTOR; RELAXATION; BARRIER AB An efficient electron spin-relaxation mechanism has been observed in InAs quantum dots (QDs) that manifests itself as a sharp drop in the circular polarization of the light emitted by Fe spin-light emitting diodes, which incorporate a single layer of InGaAs QDs, for a narrow range of magnetic fields around 5 T. The underlying mechanism occurs when the QDs are occupied by three-electron-hole pairs forming a tri-exciton (3X) and is a two-step process. The first step involves the spin flip of one of the three electrons mediated by the spin-orbit interaction; in the second step the 3X relaxes to its ground state via phonon emission. C1 [Russ, A. H.; Schweidenback, L.; Yasar, M.; Petrou, A.] SUNY Buffalo, Dept Phys, Buffalo, NY 14260 USA. [Li, C. H.; Hanbicki, A. T.; Kioseoglou, G.; Jonker, B. T.] USN, Res Lab, Washington, DC 20375 USA. [Korkusinski, M.] Natl Res Council Canada, Quantum Theory Grp, Inst Microstruct Sci, Ottawa, ON K1A 0R6, Canada. [Kioseoglou, G.] Univ Crete, Dept Mat Sci & Technol, GR-71003 Iraklion, Greece. RP Russ, AH (reprint author), SUNY Buffalo, Dept Phys, Buffalo, NY 14260 USA. EM gnk@materials.uoc.gr FU NRL; Office of the Naval Research [N0001410WX30262]; NSF [ECCS0824220]; ONR [N000140910113]; Moti Lal Rustgi; NRC-NSERC-BDC Nanotechnology project FX This work was supported by core programs at NRL and by the Office of the Naval Research, Contract No. N0001410WX30262. Work at SUNY Buffalo was supported by NSF Grant No. ECCS0824220 and ONR Grant No. N000140910113. A.P. acknowledges support through the Moti Lal Rustgi professorship. M.K. acknowledges support from the NRC-NSERC-BDC Nanotechnology project and discussions with P. Hawrylak. NR 23 TC 0 Z9 0 U1 0 U2 3 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 2469-9950 EI 2469-9969 J9 PHYS REV B JI Phys. Rev. B PD JUL 15 PY 2011 VL 84 IS 4 AR 045312 DI 10.1103/PhysRevB.84.045312 PG 6 WC Physics, Condensed Matter SC Physics GA 792RM UT WOS:000292766800006 ER PT J AU Li, F Folk, JE Cheng, KJ Kurimura, M Deck, JA Deschamps, JR Rothman, RB Dersch, CM Jacobson, AE Rice, KC AF Li, Feng Folk, John E. Cheng, Kejun Kurimura, Muneaki Deck, Jason A. Deschamps, Jeffrey R. Rothman, Richard B. Dersch, Christina M. Jacobson, Arthur E. Rice, Kenner C. TI Probes for narcotic receptor mediated phenomena. 43. Synthesis of the ortho-a and para-a, and improved synthesis and optical resolution of the ortho-b and para-b oxide-bridged phenylmorphans: Compounds with moderate to low opioid-receptor affinity SO BIOORGANIC & MEDICINAL CHEMISTRY LA English DT Article DE ortho-a and ortho-b oxide-bridged; phenylmorphans; para-a and para-b oxide-bridged; phenylmorphans; Synthesis; Optical resolution ID N-PHENETHYL ANALOGS; ISOMERS AB N-Phenethyl-substituted ortho-a and para-a oxide-bridged phenylmorphans have been obtained through an improved synthesis and their binding affinity examined at the various opioid receptors. Although the N-phenethyl substituent showed much greater affinity for mu- and kappa-opioid receptors than their N-methyl relatives (e. g., K(i) = 167 nM and 171 nM at mu- and kappa-receptors vs > 2800 and 7500 nM for the N-methyl ortho-a oxide-bridged phenylmorphan), the a-isomers were not examined further because of their relatively low affinity. The N-phenethyl substituted ortho-b and para-b oxide-bridged phenylmorphans were also synthesized and their enantiomers were obtained using supercritical fluid chromatography. Of the four enantiomers, only the (+)-ortho-b isomer had moderate affinity for mu- and kappa-receptors (K(i) = 49 and 42 nM, respectively, and it was found to also have moderate mu- and kappa-opioid antagonist activity in the [(35)S]GTP-gamma-S assay (K(e) = 31 and 26 nM). (C) 2011 Published by Elsevier C1 [Li, Feng; Folk, John E.; Cheng, Kejun; Kurimura, Muneaki; Deck, Jason A.; Jacobson, Arthur E.; Rice, Kenner C.] NIDA, Drug Design & Synth Sect, Chem Biol Res Branch, Bethesda, MD 20892 USA. [Li, Feng; Folk, John E.; Cheng, Kejun; Kurimura, Muneaki; Deck, Jason A.; Jacobson, Arthur E.; Rice, Kenner C.] NIAAA, NIH, Dept Hlth & Human Serv, Bethesda, MD 20892 USA. [Deschamps, Jeffrey R.] USN, Res Lab, Ctr Biomol Sci & Engn, Washington, DC 20375 USA. [Deschamps, Jeffrey R.] NIH, Ctr Mol Modeling, Div Computat Biosci, CIT,DHHS, Bethesda, MD 20892 USA. NIDA, Addict Res Ctr, Clin Psychopharmacol Sect, Chem Biol Res Branch,NIH,Dept Hlth & Human Serv, Baltimore, MD 21224 USA. RP Rice, KC (reprint author), NIDA, Drug Design & Synth Sect, Chem Biol Res Branch, 5625 Fishers Lane,Room 4N03, Bethesda, MD 20892 USA. EM kr21f@nih.gov OI Deschamps, Jeffrey/0000-0001-5845-0010 FU NIH of the National Institute on Drug Abuse (NIDA); National Institute of Alcohol Abuse and Alcoholism; NIDA through Naval Research Laboratory (NRL) [Y1-DA1101] FX The work of the Drug Design and Synthesis Section, CBRB, NIDA, & NIAAA, was supported by the NIH Intramural Research Programs of the National Institute on Drug Abuse (NIDA) and the National Institute of Alcohol Abuse and Alcoholism. The Clinical Psychopharmacology Section, CBRB, NIDA, was supported by the NIH Intramural Research Program of the National Institute on Drug Abuse (NIDA). We thank the Averica Discovery Services, J.P. Kiplinger, President, Worcester, MA, for carrying out the supercritical fluid chromatography used to obtain the enantiomers of 16 and 19. We also thank Dr. Klaus Gawrisch and Dr. Walter Teague (Laboratory of Membrane Biochemistry and Biophysics, NIAAA, for NMR spectral data. The authors express their thanks to Noel Whittaker and Wesley White, Laboratory of Analytical Chemistry, NIDDK, for mass spectral data and 1H NMR spectral data. The X-ray crystallographic work was supported by NIDA through an Interagency Agreement #Y1-DA1101 with the Naval Research Laboratory (NRL). NR 17 TC 3 Z9 3 U1 0 U2 3 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0968-0896 J9 BIOORGAN MED CHEM JI Bioorg. Med. Chem. PD JUL 15 PY 2011 VL 19 IS 14 BP 4330 EP 4337 DI 10.1016/j.bmc.2011.05.035 PG 8 WC Biochemistry & Molecular Biology; Chemistry, Medicinal; Chemistry, Organic SC Biochemistry & Molecular Biology; Pharmacology & Pharmacy; Chemistry GA 786JD UT WOS:000292301200018 PM 21684752 ER PT J AU Tehrani, M Luhrs, CC Al-Haik, MS Trevino, J Zea, H AF Tehrani, M. Luhrs, C. C. Al-Haik, M. S. Trevino, J. Zea, H. TI Synthesis of WS2 nanostructures from the reaction of WO3 with CS2 and mechanical characterization of WS2 nanotube composites SO NANOTECHNOLOGY LA English DT Article ID FULLERENE-LIKE STRUCTURES; CARBON NANOTUBES; FRACTURE-TOUGHNESS; MOS2; NANOPARTICLES; EPOXY; NANOCOMPOSITES; RESISTANCE; ALIGNMENT; COATINGS AB Tungsten disulfide (WS2) nanometer sheets, spheres, fibers and tubes were generated by a synthetic pathway that avoids the use of H2S as the source of sulfur and employs instead CS2 vapor, carried by an Ar or N-2/H-2 stream in a heated tubular furnace, for the reaction with WO3 precursor powders. The experiments were conducted at temperatures between 700 and 1000 degrees C, while the reaction times expanded between 30 min and 24 h. Characterization methods used to analyze the products of the synthesis include TEM, SEM, XRD and EDX. We found a strong correlation between precursor and product microstructure, although the temperature and reaction times play a critical role in the products' microstructural features as well. WS2 inorganic fullerene (IF) nanospheres are generated in a wide window of conditions, while nanotubes and nanofibers are only produced at high temperatures or long reaction times. A proposed growth mechanism based on the CS2 synthetic approach is presented. Nanoindentation and nano-impulse techniques were used to characterize the mechanical properties of polymer matrix-WS2 nanotube composites, finding them superior to equivalent SWCNT composites. The improvements in toughness of nanocomposites based on WS2 can be attributed to geometrical and morphological effects that assisted several toughening mechanisms such as crack pinning and the formation of an immobilized polymeric interphase around the nanotubes. C1 [Luhrs, C. C.] USN, Dept Mech & Aerosp Engn, Postgrad Sch, Monterey, CA 93943 USA. [Tehrani, M.; Al-Haik, M. S.] Virginia Tech, Dept Engn Sci & Mech, Blacksburg, VA 24061 USA. [Trevino, J.] Univ New Mexico, Dept Mech Engn, Albuquerque, NM 87131 USA. [Zea, H.] Univ Nacl Colombia, Dept Ingn Quim & Ambiental, Bogota 11001, Colombia. RP Luhrs, CC (reprint author), USN, Dept Mech & Aerosp Engn, Postgrad Sch, Monterey, CA 93943 USA. EM ccluhrs@nps.edu RI Al-Haik, Marwan/L-7732-2014 OI Al-Haik, Marwan/0000-0001-7465-0274 FU National Science Foundation (NSF) [EEC-0741525, NSF-CMMI-0846589] FX The authors greatly acknowledge the support of the National Science Foundation (NSF) Awards # EEC-0741525 and NSF-CMMI-0846589. NR 46 TC 6 Z9 6 U1 7 U2 93 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0957-4484 J9 NANOTECHNOLOGY JI Nanotechnology PD JUL 15 PY 2011 VL 22 IS 28 AR 285714 DI 10.1088/0957-4484/22/28/285714 PG 10 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied SC Science & Technology - Other Topics; Materials Science; Physics GA 775NX UT WOS:000291468000045 PM 21659689 ER PT J AU Yin, YJ Zhou, JJ Mansour, AN Zhou, XY AF Yin, Yijing Zhou, Juanjuan Mansour, Azzam N. Zhou, Xiangyang TI Effect of NaI/I-2 mediators on properties of PEO/LiAlO2 based all-solid-state supercapacitors SO JOURNAL OF POWER SOURCES LA English DT Article DE PEO/LiAlO2/AC; NaI/I-2 mediator; Solid-state; Supercapacitor ID POLYMER-BASED SUPERCAPACITOR; NANOCRYSTALLINE SOLAR-CELLS; ELECTROCHEMICAL CAPACITORS; COMPOSITE ELECTRODES; CARBON MATERIALS; RUTHENIUM OXIDE; ION BATTERIES; SULFURIC-ACID; REDOX COUPLE; ELECTROLYTES AB NaI/I-2 mediators and activated carbon were added into poly(ethylene oxide) (PEO)/lithium aluminate (LiAlO2) electrolyte to fabricate composite electrodes. All solid-state supercapacitors were fabricated using the as prepared composite electrodes and a Nafion 117 membrane as a separator. Cyclic voltam-metry, electrochemical impedance spectroscopy. and galvanostatic charge/discharge measurements were conducted to evaluate the electrochemical properties of the supercapacitors. With the addition of NaI/I-2 mediators, the specific capacitance increased by 27 folds up to 150 Fg(-1). The specific capacitance increased with increases in the concentration of mediators in the electrodes. The addition of mediators also reduced the electrode resistance and rendered a higher electron transfer rate between mediator and mediator. The stability of the all-solid-state supercapacitor was tested over 2000 charge/discharge cycles. (C) 2011 Elsevier B.V. All rights reserved. C1 [Yin, Yijing; Zhou, Juanjuan; Zhou, Xiangyang] Univ Miami, Dept Mech & Aerosp Engn, Coral Gables, FL 33124 USA. [Mansour, Azzam N.] NSWC, Syst & Mat Power, Bethesda, MD 20817 USA. [Mansour, Azzam N.] NSWC, Protect Branch, Caederock Div, Bethesda, MD 20817 USA. RP Zhou, XY (reprint author), Univ Miami, Dept Mech & Aerosp Engn, POB 248294, Coral Gables, FL 33124 USA. EM xzhou@miami.edu FU Office of Naval Research (ONR) [N00014-08-1-0332, N00014-08-WX-20797] FX The authors would like to thank Office of Naval Research (ONR) for financial support under award numbers N00014-08-1-0332 and N00014-08-WX-20797. We also thank Dr. j.A. Zaykoski (NSWC, Carderock Division) for providing the XRD pattern presented in this manuscript. NR 44 TC 15 Z9 18 U1 5 U2 29 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0378-7753 J9 J POWER SOURCES JI J. Power Sources PD JUL 15 PY 2011 VL 196 IS 14 SI SI BP 5997 EP 6002 DI 10.1016/j.jpowsour.2011.02.079 PG 6 WC Chemistry, Physical; Electrochemistry; Energy & Fuels; Materials Science, Multidisciplinary SC Chemistry; Electrochemistry; Energy & Fuels; Materials Science GA 767EB UT WOS:000290837000032 ER PT J AU Trammell, SA Dressick, WJ Melde, BJ Moore, M AF Trammell, Scott A. Dressick, Walter J. Melde, Brian J. Moore, Martin TI Photocurrents from the Direct Irradiation of a Donor-Acceptor Complex Contained in a Thin Film on Indium Tin Oxide SO JOURNAL OF PHYSICAL CHEMISTRY C LA English DT Article ID ELECTRON-TRANSFER REACTIONS; PHOTO-ELECTROCHEMICAL CELL; EXCITED-STATE PROPERTIES; PHOTOELECTROCHEMICAL CELLS; CONJUGATED POLYMERS; CHARGE-TRANSFER; RUTHENIUM(II) PHOTOSENSITIZERS; ENERGY-TRANSFER; VISIBLE-LIGHT; SOLAR-CELLS AB We describe the performance of a photoelectrochemical cell based on an electron donor-acceptor (EDA) complex formed by the association of tetraphenylborate anion with a viologen dication siloxane film immobilized on an indium tin oxide (ITO) electrode. Visible irradiation of a weak absorbance band of the EDA complex leads to simultaneous photoreduction of the viologen and photooxidation of the tetraphenylborate, forming a viologen monocation radical and tetraphenylborate radical. Spontaneous decomposition of the latter to products incapable of further reaction inhibits reverse electron transfer, permitting harvesting of the redox equivalents stored as the viologen monocation radical at the electrode. Results of statistically designed two-level factorial experiments indicate that the photo current increases with light intensity (L) and viologen coverage (P), but decreases with viologen siloxane film age (A). Although the solution BPh4- concentration (F) does not significantly affect the photocurrent response under our experimental conditions, the nature of the electrolyte anion (C) does. Although significant interactions among the L, P, A, and C variables exist, our analyses provide a model that (1) describes the viologen film aging; (2) adequately predicts cell photocurrent responses as functions of levels of the L, P, and, to a somewhat lesser extent, A variables; and (3) identifies areas for improvement and optimization of cell performance. C1 [Trammell, Scott A.; Dressick, Walter J.; Melde, Brian J.; Moore, Martin] USN, Ctr Biomol Sci & Engn, Res Lab, Washington, DC 20375 USA. RP Trammell, SA (reprint author), USN, Ctr Biomol Sci & Engn, Res Lab, Code 6900,4555 Overlook Ave SW, Washington, DC 20375 USA. EM scott.trammell@nrl.navy.mil FU Office of Naval Research (ONR) through the Naval Research Laboratory FX We gratefully acknowledge financial support for this research from the Office of Naval Research (ONR) through the Naval Research Laboratory Core 6.1 Research program. NR 99 TC 9 Z9 9 U1 0 U2 21 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1932-7447 J9 J PHYS CHEM C JI J. Phys. Chem. C PD JUL 14 PY 2011 VL 115 IS 27 BP 13446 EP 13461 DI 10.1021/jp2023988 PG 16 WC Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Chemistry; Science & Technology - Other Topics; Materials Science GA 788YG UT WOS:000292479700041 ER PT J AU Delehanty, JB Bradburne, CE Susumu, K Boeneman, K Mei, BC Farrell, D Blanco-Canosa, JB Dawson, PE Mattoussi, H Medintz, IL AF Delehanty, James B. Bradburne, Christopher E. Susumu, Kimihiro Boeneman, Kelly Mei, Bing C. Farrell, Dorothy Blanco-Canosa, Juan B. Dawson, Philip E. Mattoussi, Hedi Medintz, Igor L. TI Spatiotemporal Multicolor Labeling of Individual Cells Using Peptide-Functionalized Quantum Dots and Mixed Delivery Techniques SO JOURNAL OF THE AMERICAN CHEMICAL SOCIETY LA English DT Article ID RESONANCE ENERGY-TRANSFER; INTRACELLULAR DELIVERY; PROTEIN; STABILITY; NANOPARTICLES; POLYMERS; PROGRESS; LIGANDS AB Multicolor fluorescent labeling of both intra- and extracellular structures is a powerful technique for simultaneous monitoring of multiple complex biochemical processes. This approach remains extremely challenging, however, as it often necessitates the combinatorial use of numerous targeting probes (e.g., antibodies), multistep bioconjugation chemistries, different delivery strategies (e.g., electroporation or transfection reagents), cellular fixation coupled with membrane permeabilization, and complex spectral deconvolution. Here, we present a nanoparticle-based fluorescence labeling strategy for the multicolor labeling of distinct subcellular compartments within live cells without the need for antibody conjugation or cellular fixation/permeabilization. This multipronged approach incorporates an array of delivery strategies, which localize semiconductor quantum dots (Qps) to various subcellular structures. QD uptake is implemented in a spaciotemporal manner by staggering the delivery of QD-peptide composites and exploiting various innate (peptide-mediated endocytosis, peptide-membrane interaction, polymer-based transfection) along with physical (microinjection) cellular delivery modalities to live cells growing in culture over a 4 day period. Imaging of the different intracellular labels is simplified by the unique photophysical characteristics of the QDs in combination with Forster resonance energy transfer sensitization, which allow for multiple spectral windows to be accessed with one excitation wavelength. Using this overall approach, QDs were targeted to both early and late endosomes, the cellular cytosol, and the plasma membrane in live cells, ultimately allowing for simultaneous five-color fluorescent imaging. C1 [Delehanty, James B.; Bradburne, Christopher E.; Boeneman, Kelly; Medintz, Igor L.] USN, Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. [Susumu, Kimihiro; Mei, Bing C.; Farrell, Dorothy; Mattoussi, Hedi] USN, Res Lab, Div Opt Sci, Washington, DC 20375 USA. [Blanco-Canosa, Juan B.; Dawson, Philip E.] Scripps Res Inst, La Jolla, CA 92037 USA. RP Delehanty, JB (reprint author), USN, Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. EM james.delehanty@nrl.navy.mil; igor.medintz@nrl.navy.mil RI Gemmill, Kelly/G-2167-2012 FU NRC FX We acknowledge DTRA/ARO, DARPA, NRL, and the NRL-NSI. C.E.B. and D.F. acknowledge NRC fellowships. J.B.B.-C. acknowledges a Marie Curie IOF. NR 43 TC 62 Z9 63 U1 9 U2 79 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0002-7863 J9 J AM CHEM SOC JI J. Am. Chem. Soc. PD JUL 13 PY 2011 VL 133 IS 27 BP 10482 EP 10489 DI 10.1021/ja200555z PG 8 WC Chemistry, Multidisciplinary SC Chemistry GA 797SG UT WOS:000293149800033 PM 21627173 ER PT J AU Pootong, P Serichantalergs, O Bodhidatta, L Poly, F Guerry, P Mason, CJ AF Pootong, Piyarat Serichantalergs, Oralak Bodhidatta, Ladaporn Poly, Frederic Guerry, Patricia Mason, Carl J. TI Distribution of flagella secreted protein and integral membrane protein among Campylobacter jejuni isolated from Thailand SO GUT PATHOGENS LA English DT Article ID GENOME SEQUENCE; HOST-CELLS; INVASION; APPARATUS AB Background: Campylobacter jejuni, a gram-negative bacterium, is a frequent cause of gastrointestinal food-borne illness in humans throughout the world. There are several reports that the virulence of C. jejuni might be modulated by non-flagellar proteins that are secreted through the filament. Recently, FspA (Flagella secreted proteins) have been described. Two alleles of fspA (fspA1 and fspA2) based on sequence analysis were previously reported and only the fspA2 allele was found in Thai isolates. The aim of this study is to analyze the deduced amino acid sequences fspA and the adjacent putative integral membrane protein from 103 Thai C. jejuni isolates. Results: A total of 103 representative C. jejuni isolates were amplified by PCR for the fspA gene and the adjacent integral membrane protein gene. Two PCR product sizes were amplified using the same primers, an approximately 1600-bp PCR product from 19 strains that contained fspA and integral membrane protein genes and an approximately 800-bp PCR product from 84 strains that contained only the fspA gene. DNA sequencing was performed on the amplified products. The deduced amino acid sequences of both genes were analyzed separately using CLC Free Workbench 4 software. The analysis revealed three groups of FspA. Only FspA group 1 sequences (19/103) (corresponding to fspA1) consisting of 5 subgroups were associated with the adjacent gene encoding the integral membrane protein. FspA group 2 was the largest group (67/103) consisting of 9 subgroups. FspA group 2p (17/103) consisting of 7 subgroups was found to contain stop codons at a position before the terminal 142 position. Conclusions: This study reveals greater heterogeneity of FspA (group 1, 2 and 2p) among Thai C. jejuni isolates than previously reported. Furthermore, the subgroups of FspA groups 1 were associated with groups of integral membrane protein. The significance of these different FspA variants to virulence requires further study. C1 [Pootong, Piyarat; Serichantalergs, Oralak; Bodhidatta, Ladaporn; Mason, Carl J.] Armed Forces Res Inst Med Sci, Enter Dis Dept, Bangkok 10400, Thailand. [Poly, Frederic; Guerry, Patricia] USN, Med Res Ctr, Enter Dis Dept, Silver Spring, MD 20910 USA. RP Pootong, P (reprint author), Armed Forces Res Inst Med Sci, Enter Dis Dept, Bangkok 10400, Thailand. EM piyaratp@afrims.org RI Guerry, Patricia/A-8024-2011; OI MASON, CARL/0000-0002-3676-2811 FU Walter Reed Army Institute of Research, Washington, DC, USA FX All study projects described here were financially supported by the Military Infectious Diseases Research Program, Walter Reed Army Institute of Research, Washington, DC, USA. We would like to thank Apichai Srijan, Department of Enteric Diseases at the Armed Forces Research Institute of Medical Sciences (AFRIMS), for his kind provision of C. jejuni strains. The views expressed in this article are those of the author and do not reflect the official policy of the Department of the Army, Department of Defense, or the U.S. Government. NR 17 TC 0 Z9 0 U1 0 U2 3 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1757-4749 J9 GUT PATHOG JI Gut Pathogens PD JUL 12 PY 2011 VL 3 AR 11 DI 10.1186/1757-4749-3-11 PG 7 WC Gastroenterology & Hepatology; Microbiology SC Gastroenterology & Hepatology; Microbiology GA 879OK UT WOS:000299339900001 PM 21745410 ER PT J AU Friedman, AL Robinson, JT Perkins, FK Campbell, PM AF Friedman, Adam L. Robinson, Jeremy T. Perkins, F. Keith Campbell, Paul M. TI Extraordinary magnetoresistance in shunted chemical vapor deposition grown graphene devices SO APPLIED PHYSICS LETTERS LA English DT Article ID READ-HEAD SENSORS; LINEAR MAGNETORESISTANCE; HYBRID STRUCTURE; QUANTUM; SEMICONDUCTORS; FILMS AB We report gate tunable linear magnetoresistances (MRs) of similar to 600% at 12 T in metal-shunted devices fabricated on chemical vapor deposition (CVD) grown graphene. The effect occurs due to decreasing conduction through the shunt as the magnetic field increases (known as the extraordinary magnetoresistance effect) and yields an MR that is at least an order-of-magnitude higher than in un-shunted graphene devices. [doi: 10.1063/1.3610565] C1 [Friedman, Adam L.; Robinson, Jeremy T.; Perkins, F. Keith; Campbell, Paul M.] USN, Res Lab, Washington, DC 20375 USA. RP Friedman, AL (reprint author), USN, Res Lab, Code 6876, Washington, DC 20375 USA. EM adam.friedman@nrl.navy.mil RI Friedman, Adam/D-9610-2011; Robinson, Jeremy/F-2748-2010 OI Friedman, Adam/0000-0003-0597-5432; NR 21 TC 7 Z9 7 U1 0 U2 20 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD JUL 11 PY 2011 VL 99 IS 2 AR 022108 DI 10.1063/1.3610565 PG 3 WC Physics, Applied SC Physics GA 792VA UT WOS:000292777300030 ER PT J AU Ikyo, BA Marko, IP Adams, AR Sweeney, SJ Canedy, CL Vurgaftman, I Kim, CS Kim, M Bewley, WW Meyer, JR AF Ikyo, B. A. Marko, I. P. Adams, A. R. Sweeney, S. J. Canedy, C. L. Vurgaftman, I. Kim, C. S. Kim, M. Bewley, W. W. Meyer, J. R. TI Temperature dependence of 4.1 mu m mid-infrared type II "W" interband cascade lasers SO APPLIED PHYSICS LETTERS LA English DT Article ID PRESSURE AB The thermal properties of 5-stage "W" Interband-Cascade Lasers emitting at 4.1 mu m at room temperature (RT) are investigated by measuring the lasing and spontaneous emission properties as a function of temperature and hydrostatic pressure up to 1 GPa. Experiments show that at RT more than 90% of threshold current of these devices is due to non-radiative loss processes. We also find that the threshold current density dependence on temperature can be fitted with a single exponential function over a wide temperature range with a characteristic temperature, T(0), of 45 K. The relatively high temperature sensitivity in these devices is attributable to the large non-radiative current contribution coupled with non-pinning of the carrier density above threshold. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3606533] C1 [Ikyo, B. A.; Marko, I. P.; Adams, A. R.; Sweeney, S. J.] Univ Surrey, Dept Phys, Adv Technol Inst, Guildford GU2 7XH, Surrey, England. [Canedy, C. L.; Vurgaftman, I.; Kim, C. S.; Kim, M.; Bewley, W. W.; Meyer, J. R.] USN, Res Lab, Washington, DC 20375 USA. RP Ikyo, BA (reprint author), Univ Surrey, Dept Phys, Adv Technol Inst, Guildford GU2 7XH, Surrey, England. EM s.sweeney@surrey.ac.uk NR 17 TC 5 Z9 6 U1 2 U2 9 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD JUL 11 PY 2011 VL 99 IS 2 AR 021102 DI 10.1063/1.3606533 PG 3 WC Physics, Applied SC Physics GA 792VA UT WOS:000292777300002 ER PT J AU Drake, AJ Djorgovski, SG Mahabal, A Anderson, J Roy, R Mohan, V Ravindranath, S Frail, D Gezari, S Neill, JD Ho, LC Prieto, JL Thompson, D Thorstensen, J Wagner, M Kowalski, R Chiang, J Grove, JE Schinzel, FK Wood, DL Carrasco, L Recillas, E Kewley, L Archana, KN Basu, A Wadadekar, Y Kumar, B Myers, AD Phinney, ES Williams, R Graham, MJ Catelan, M Beshore, E Larson, S Christensen, E AF Drake, A. J. Djorgovski, S. G. Mahabal, A. Anderson, J. Roy, R. Mohan, V. Ravindranath, S. Frail, D. Gezari, S. Neill, James D. Ho, L. C. Prieto, J. L. Thompson, D. Thorstensen, J. Wagner, M. Kowalski, R. Chiang, J. Grove, J. E. Schinzel, F. K. Wood, D. L. Carrasco, L. Recillas, E. Kewley, L. Archana, K. N. Basu, Aritra Wadadekar, Yogesh Kumar, Brijesh Myers, A. D. Phinney, E. S. Williams, R. Graham, M. J. Catelan, M. Beshore, E. Larson, S. Christensen, E. TI THE DISCOVERY AND NATURE OF THE OPTICAL TRANSIENT CSS100217:102913+404220 SO ASTROPHYSICAL JOURNAL LA English DT Article DE galaxies: active; galaxies: nuclei; galaxies: stellar content; supernovae: general ID ACTIVE GALACTIC NUCLEI; DIGITAL SKY SURVEY; LINE SEYFERT-1 GALAXIES; LARGE-AREA TELESCOPE; GRAVITATING ACCRETION DISKS; TIDAL DISRUPTION EVENTS; HUBBLE-SPACE-TELESCOPE; GAMMA-RAY BURSTS; HOST GALAXIES; RADIO-LOUD AB We report on the discovery and observations of the extremely luminous optical transient CSS100217:102913+404220 (CSS100217 hereafter). Spectroscopic observations showed that this transient was coincident with a galaxy at red-shift z = 0.147 and reached an apparent magnitude of V similar to 16.3. After correcting for foreground Galactic extinction we determine the absolute magnitude to be M-V = -22.7 approximately 45 days after maximum light. Over a period of 287 rest-frame days, this event had an integrated bolometric luminosity of 1.3 x 10(52) erg based on time-averaged bolometric corrections of similar to 15 from V-and R-band observations. Analysis of the pre-outburst Sloan Digital Sky Survey (SDSS) spectrum of the source shows features consistent with a narrow-line Seyfert 1 galaxy. High-resolution Hubble Space Telescope and Keck follow-up observations show that the event occurred within 150 pc of the nucleus of the galaxy, suggesting a possible link to the active nuclear region. However, the rapid outburst along with photometric and spectroscopic evolution are much more consistent with a luminous supernova. Line diagnostics suggest that the host galaxy is undergoing significant star formation. We use extensive follow-up of the event along with archival Catalina Sky Survey NEO search and SDSS data to investigate the three most likely sources of such an event: (1) an extremely luminous supernova, (2) the tidal disruption of a star by the massive nuclear black hole, and (3) variability of the central active galactic nucleus (AGN). We find that CSS100217 was likely an extremely luminous Type IIn supernova and occurred within the range of the narrow-line region of an AGN. We discuss how similar events may have been missed in past supernova surveys because of confusion with AGN activity. C1 [Drake, A. J.; Djorgovski, S. G.; Mahabal, A.; Neill, James D.; Phinney, E. S.; Williams, R.; Graham, M. J.] CALTECH, Pasadena, CA 91225 USA. [Anderson, J.] STScI, Baltimore, MD 21218 USA. [Roy, R.; Kumar, Brijesh] Aryabhatta Res Inst Observ Sci, Naini Tal 263129, Uttarakhand, India. [Mohan, V.; Ravindranath, S.] IUCAA, Pune 411007, Maharashtra, India. [Frail, D.] NRAO, Tucson, AZ 85721 USA. [Gezari, S.] Johns Hopkins Univ, Dept Phys & Astron, Bloomberg Ctr 366, Baltimore, MD 21218 USA. [Ho, L. C.; Prieto, J. L.] Carnegie Observ, Pasadena, CA 91101 USA. [Thompson, D.; Wagner, M.] Univ Arizona, LBT, Tucson, AZ 85721 USA. [Thorstensen, J.] Dartmouth Coll, Wilder Lab 6127, Hanover, NH 03755 USA. [Kowalski, R.; Beshore, E.; Larson, S.] Univ Arizona, Dept Planetary Sci, Lunar & Planetary Lab, Tucson, AZ 85721 USA. [Chiang, J.] Stanford Univ, SLAC Natl Accelerator Lab, Kavli Inst Particle Astrophys & Cosmol, WW Hansen Expt Phys Lab, Stanford, CA 94305 USA. [Grove, J. E.; Wood, D. L.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. [Schinzel, F. K.] Max Planck Inst Radioastron, D-53121 Bonn, Germany. [Carrasco, L.; Recillas, E.] INAOE, Puebla, Mexico. [Kewley, L.] IFA, Hilo, HI 96720 USA. [Archana, K. N.] Mahatma Gandhi Univ, Sch Comp Sci, Kottayam 686560, Kerala, India. [Archana, K. N.; Basu, Aritra; Wadadekar, Yogesh] TIFR, Natl Ctr Radio Astrophys, Pune 411007, Maharashtra, India. [Myers, A. D.] Univ Illinois, Dept Astron, Urbana, IL 61801 USA. [Catelan, M.] Pontificia Univ Catolica Chile, Dept Astron & Astrofis, Santiago, Chile. [Christensen, E.] Gemini Observ, La Serena, CL, Chile. RP Drake, AJ (reprint author), CALTECH, 1200 E Calif Blvd, Pasadena, CA 91225 USA. FU U.S. National Science Foundation [AST-0909182, CNS-0540369, AST-0407448, AST-0407297]; Space Telescope Science Institute under NASA [NAS 5-26555]; NASA [NAS 5-26555, 08-FERMI08-0025, NNG05GF22G, HF-51261.01]; Ajax Foundation; Proyecto Basal [PFB-06/2007]; FONDAP Centro de Astrofisica [15010003]; MIDEPLAN [P07-021-F] FX We thank Minjin Kim for help in analyzing the SDSS spectrum. The CRTS survey is supported by the U.S. National Science Foundation under grants AST-0909182 and CNS-0540369. Support for program number GO proposal 12117 was provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555. The work at Caltech was supported in part by the NASA Fermi grant 08-FERMI08-0025, and by the Ajax Foundation. The CSS survey is funded by the National Aeronautics and Space Administration under grant no. NNG05GF22G issued through the Science Mission Directorate Near-Earth Objects Observations Program. J.L.P. acknowledges support from NASA through Hubble Fellowship Grant HF-51261.01-A awarded by the STScI, which is operated by AURA, Inc. for NASA, under contract NAS 5-26555. The PQ survey is supported by the U. S. National Science Foundation under Grants AST-0407448 and AST-0407297. Support for M. C. is provided by Proyecto Basal PFB-06/2007, by FONDAP Centro de Astrofisica 15010003, and by MIDEPLAN Rs Programa Iniciativa Cientifica Milenio through grant P07-021-F, awarded to The Milky Way Millennium Nucleus. GALEX (Galaxy Evolution Explorer) is a NASA Small Explorer, launched in 2003 April. We gratefully acknowledge NASA's support for construction, operation, and science analysis for the GALEX mission, developed in cooperation with the Centre National d'Etudes Spatiales of France and the Korean Ministry of Science and Technology. The Expanded Very Large Array is operated by the National Radio Astronomy Observatory, a facility of the National Science Foundation operated under cooperative agreement by Associated Universities, Inc. We thank the staff of GMRT that made these observations possible. GMRT is run by the National Centre for Radio Astrophysics of the Tata Institute of Fundamental Research. The Fermi LAT Collaboration acknowledges support from a number of agencies and institutes for both the development and the operation of the LAT as well as scientific data analysis. These include NASA and DOE in the United States, CEA/Irfu and IN2P3/CNRS in France, ASI and INFN in Italy, MEXT, KEK, and JAXA in Japan, and the K. A. Wallenberg Foundation, the Swedish Research Council and the National Space Board in Sweden. We thank all the observers at ARIES who provided their valuable time and support for the observations of this event. The UBVRI observations presented here are included by R. R. in partial fulfillment of the requirements for a Ph. D. degree. NR 131 TC 26 Z9 26 U1 1 U2 12 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X EI 1538-4357 J9 ASTROPHYS J JI Astrophys. J. PD JUL 10 PY 2011 VL 735 IS 2 AR 106 DI 10.1088/0004-637X/735/2/106 PG 21 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 783NF UT WOS:000292089700039 ER PT J AU Johnson, H Raymond, JC Murphy, NA Giordano, S Ko, YK Ciaravella, A Suleiman, R AF Johnson, H. Raymond, J. C. Murphy, N. A. Giordano, S. Ko, Y. -K. Ciaravella, A. Suleiman, R. TI TRANSITION REGION EMISSION FROM SOLAR FLARES DURING THE IMPULSIVE PHASE SO ASTROPHYSICAL JOURNAL LA English DT Article DE Sun: activity; Sun: corona; Sun: coronal mass ejections (CMEs); Sun: flares; Sun: UV radiation ID CORONAL MASS EJECTION; 2002 JULY 23; HARD X-RAY; CHROMOSPHERIC EVAPORATION; WHITE-LIGHT; SOHO OBSERVATIONS; ATOMIC DATABASE; SOURCE MOTIONS; RHESSI; PLASMA AB There are relatively few observations of UV emission during the impulsive phases of solar flares, so the nature of that emission is poorly known. Photons produced by solar flares can resonantly scatter off atoms and ions in the corona. Based on off-limb measurements by the Solar and Heliospheric Observatory/Ultraviolet Coronagraph Spectrometer, we derive the O VI lambda 1032 luminosities for 29 flares during the impulsive phase and the Ly alpha luminosities of 5 flares, and we compare them with X-ray luminosities from GOES measurements. The upper transition region and lower transition region luminosities of the events observed are comparable. They are also comparable to the luminosity of the X-ray emitting gas at the beginning of the flare, but after 10-15 minutes the X-ray luminosity usually dominates. In some cases, we can use Doppler dimming to estimate flow speeds of the O VI emitting gas, and five events show speeds in the 40-80 km s(-1) range. The O VI emission could originate in gas evaporating to fill the X-ray flare loops, in heated chromospheric gas at the footpoints, or in heated prominence material in the coronal mass ejection. All three sources may contribute in different events or even in a single event, and the relative timing of UV and X-ray brightness peaks, the flow speeds, and the total O VI luminosity favor each source in one or more events. C1 [Johnson, H.; Raymond, J. C.; Murphy, N. A.; Suleiman, R.] Harvard Smithsonian Ctr Astrophys, Cambridge, MA 02138 USA. [Johnson, H.] Northeastern Univ, Dept Phys, Dana Res Ctr 111, Boston, MA 02115 USA. [Giordano, S.] Osserv Astron Torino, INAF, I-10025 Pino Torinese, Italy. [Ko, Y. -K.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. [Ciaravella, A.] Osserv Astron Palermo, INAF, I-90134 Palermo, Italy. RP Johnson, H (reprint author), Harvard Smithsonian Ctr Astrophys, 60 Garden St, Cambridge, MA 02138 USA. OI Ciaravella, Angela/0000-0002-3127-8078; Murphy, Nicholas/0000-0001-6628-8033; Giordano, Silvio/0000-0002-3468-8566 FU NASA [NNG06GG78G, NNX09AB17G-R] FX This work was supported by NASA grants NNG06GG78G and NNX09AB17G-R to the Smithsonian Astrophysical Observatory. SOHO is a project of international cooperation between ESA and NASA. NR 50 TC 5 Z9 5 U1 0 U2 6 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X EI 1538-4357 J9 ASTROPHYS J JI Astrophys. J. PD JUL 10 PY 2011 VL 735 IS 2 AR 70 DI 10.1088/0004-637X/735/2/70 PG 14 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 783NF UT WOS:000292089700003 ER PT J AU Sibeck, DG Lin, RQ AF Sibeck, D. G. Lin, R. -Q. TI Concerning the motion and orientation of flux transfer events produced by component and antiparallel reconnection SO JOURNAL OF GEOPHYSICAL RESEARCH-SPACE PHYSICS LA English DT Article ID INTERPLANETARY MAGNETIC-FIELD; HIGH-LATITUDE MAGNETOPAUSE; DAYSIDE RECONNECTION; AMPTE/IRM OBSERVATIONS; EARTHS MAGNETOSPHERE; MAGNETOSHEATH FLOW; SIGNATURES; CONVECTION; MODEL; IMF AB We employ the Cooling et al. (2001) model to predict the location, orientation, motion, and signatures of flux transfer events (FTEs) generated at the solstices and equinoxes along extended subsolar component and high-latitude antiparallel reconnection curves for typical solar wind plasma conditions and various interplanetary magnetic field (IMF) strengths and directions. In general, events generated by the two mechanisms maintain the strikingly different orientations they begin with as they move toward the terminator in opposite pairs of magnetopause quadrants. The curves along which events generated by component reconnection form bow toward the winter cusp. Events generated by antiparallel reconnection form on the equatorial magnetopause during intervals of strongly southward IMF orientation during the equinoxes, form in the winter hemisphere and only reach the dayside equatorial magnetopause during the solstices when the IMF strength is very large and the IMF points strongly southward, never reach the equatorial dayside magnetopause when the IMF has a substantial dawnward or duskward component, and never reach the equatorial flank magnetopause during intervals of northward and dawnward or duskward IMF orientation. Magnetosheath magnetic fields typically have strong components transverse to events generated by component reconnection but only weak components transverse to the axes of events generated by antiparallel reconnection. As a result, much stronger bipolar magnetic field signatures normal to the nominal magnetopause should accompany events generated by component reconnection. The results presented in this paper suggest that events generated by component reconnection predominate on the dayside equatorial and flank magnetopause for most solar wind conditions. C1 [Sibeck, D. G.] NASA Goddard Space Flight Ctr, Greenbelt, MD 20723 USA. [Lin, R. -Q.] USN, Ctr Surface Warfare, Carderock Div, Bethesda, MD 20084 USA. RP Sibeck, DG (reprint author), NASA Goddard Space Flight Ctr, 8800 Greenbelt Rd,Code 674, Greenbelt, MD 20723 USA. EM david.g.sibeck@nasa.gov RI Sibeck, David/D-4424-2012 FU NASA FX The research reported in this paper was funding by NASA's Heliophysics Guest Investigator Program. The authors thank Y. Wang for encouragement and numerous helpful suggestions. NR 50 TC 5 Z9 5 U1 1 U2 1 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 0148-0227 J9 J GEOPHYS RES-SPACE JI J. Geophys. Res-Space Phys. PD JUL 9 PY 2011 VL 116 AR A07206 DI 10.1029/2011JA016560 PG 11 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 790SS UT WOS:000292610100001 ER PT J AU Erwin, SC Gao, CX Roder, C Lahnemann, J Brandt, O AF Erwin, Steven C. Gao, Cunxu Roder, Claudia Laehnemann, Jonas Brandt, Oliver TI Epitaxial Interfaces between Crystallographically Mismatched Materials SO PHYSICAL REVIEW LETTERS LA English DT Article ID DISSIMILAR MATERIALS; LATTICE-PARAMETERS; HETEROEPITAXY; ENERGY; IRON AB We report an unexpected mechanism by which an epitaxial interface can form between materials having strongly mismatched lattice constants. A simple model is proposed in which one material tilts out of the interface plane to create a coincidence-site lattice that balances two competing geometrical criteria-low residual strain and short coincidence-lattice period. We apply this model, along with complementary first-principles total-energy calculations, to the interface formed by molecular-beam epitaxy of cubic Fe on hexagonal GaN and find excellent agreement between theory and experiment. C1 [Erwin, Steven C.] USN, Ctr Computat Mat Sci, Res Lab, Washington, DC 20375 USA. [Gao, Cunxu; Roder, Claudia; Laehnemann, Jonas; Brandt, Oliver] Paul Drude Inst Festkorperelekt, D-10117 Berlin, Germany. RP Erwin, SC (reprint author), USN, Ctr Computat Mat Sci, Res Lab, Washington, DC 20375 USA. RI Gao, Cunxu/D-6688-2011; Lahnemann, Jonas/L-3589-2013; Brandt, Oliver/A-9438-2014 OI Lahnemann, Jonas/0000-0003-4072-2369; Brandt, Oliver/0000-0002-9503-5729 NR 19 TC 10 Z9 10 U1 0 U2 43 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0031-9007 J9 PHYS REV LETT JI Phys. Rev. Lett. PD JUL 8 PY 2011 VL 107 IS 2 AR 026102 DI 10.1103/PhysRevLett.107.026102 PG 4 WC Physics, Multidisciplinary SC Physics GA 789VB UT WOS:000292544000005 PM 21797624 ER PT J AU Canright, D Gangopadhyay, S Maitra, S Stanica, P AF Canright, David Gangopadhyay, Sugata Maitra, Subhamoy Stanica, Pantelimon TI Laced Boolean functions and subset sum problems in finite fields SO DISCRETE APPLIED MATHEMATICS LA English DT Article DE Boolean functions; Hamming weight; Subset sum problems; Residues modulo primes ID BOUNDS AB In this paper, we investigate some algebraic and combinatorial properties of a special Boolean function on n variables, defined using weighted sums in the residue ring modulo the least prime p >= n. We also give further evidence relating to a question raised by Shparlinski regarding this function, by computing accurately the Boolean sensitivity, thus settling the question for prime number values p = n. Finally, we propose a generalization of these functions, which we call laced functions, and compute the weight of one such, for every value of n. Published by Elsevier B.V. C1 [Canright, David; Stanica, Pantelimon] USN, Postgrad Sch, Dept Appl Math, Monterey, CA 93943 USA. [Gangopadhyay, Sugata] Indian Inst Technol, Dept Math, Roorkee 247667, Uttar Pradesh, India. [Maitra, Subhamoy] Indian Stat Inst, Appl Stat Unit, Kolkata 700108, W Bengal, India. RP Stanica, P (reprint author), USN, Postgrad Sch, Dept Appl Math, Monterey, CA 93943 USA. EM dcanright@nps.edu; gsugata@gmail.com; subho@isical.ac.in; pstanica@nps.edu NR 9 TC 2 Z9 2 U1 1 U2 5 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0166-218X EI 1872-6771 J9 DISCRETE APPL MATH JI Discret Appl. Math. PD JUL 6 PY 2011 VL 159 IS 11 BP 1059 EP 1069 DI 10.1016/j.dam.2011.03.022 PG 11 WC Mathematics, Applied SC Mathematics GA 780GP UT WOS:000291842800001 ER PT J AU Anand, P Escuadro, H Gera, R Martell, C AF Anand, Pranav Escuadro, Henry Gera, Ralucca Martell, Craig TI Triangular line graphs and word sense disambiguation SO DISCRETE APPLIED MATHEMATICS LA English DT Article DE H-line graphs; Triangular line graph; Line graph; Connectivity ID SEQUENCES AB Linguists often represent the relationships between words in a collection of text as an undirected graph G = (V, E), where V is the vocabulary and vertices are adjacent in G if and only if the words that they represent co-occur in a relevant pattern in the text. Ideally, the words with similar meanings give rise to the vertices of a component of the graph. However, many words have several distinct meanings, preventing components from characterizing distinct semantic fields. This paper examines how the structural properties of triangular line graphs motivate the use of a clustering coefficient on the triangular line graph, thereby helping to identify polysemous words. The triangular line graph of G, denoted by T(G), is the subgraph of the line graph of G where two vertices are adjacent if the corresponding edges in G belong to a K(3). (C) 2011 Elsevier B.V. All rights reserved. C1 [Escuadro, Henry] Juniata Coll, Dept Math, Huntingdon, PA 16652 USA. [Anand, Pranav] Univ Calif Santa Cruz, Dept Linguist, Santa Cruz, CA 95064 USA. [Gera, Ralucca] USN, Postgrad Sch, Dept Appl Math, Monterey, CA 93943 USA. [Martell, Craig] USN, Postgrad Sch, Dept Comp Sci, Monterey, CA 93943 USA. RP Escuadro, H (reprint author), Juniata Coll, Dept Math, Huntingdon, PA 16652 USA. EM panand@ucsc.edu; escuadro@juniata.edu; rgera@nps.edu; cmartell@nps.edu FU Department of the Navy PEO Integrated Warfare Systems FX The authors would like to thank the referees, as well as Derrick Stolee and Stephen Hartke, for their comments and suggestions regarding this publication. Also P. Anand, R. Gera and C. Martell thank the Department of the Navy PEO Integrated Warfare Systems for funding that partially supported this work. NR 14 TC 2 Z9 2 U1 0 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0166-218X J9 DISCRETE APPL MATH JI Discret Appl. Math. PD JUL 6 PY 2011 VL 159 IS 11 BP 1160 EP 1165 DI 10.1016/j.dam.2011.03.019 PG 6 WC Mathematics, Applied SC Mathematics GA 780GP UT WOS:000291842800010 ER PT J AU Puls, CP Staley, NE Moon, JS Robinson, JA Campbell, PM Tedesco, JL Myers-Ward, RL Eddy, CR Gaskill, DK Liu, Y AF Puls, Conor P. Staley, Neal E. Moon, Jeong-Sun Robinson, Joshua A. Campbell, Paul M. Tedesco, Joseph L. Myers-Ward, Rachael L. Eddy, Charles R., Jr. Gaskill, D. Kurt Liu, Ying TI Top-gate dielectric induced doping and scattering of charge carriers in epitaxial graphene SO APPLIED PHYSICS LETTERS LA English DT Article ID MOBILITY; STRAIN AB We show that an e-gun deposited dielectric impose severe limits on epitaxial graphene-based device performance based on Raman spectroscopy and low-temperature transport measurements. Specifically, we show from studies of epitaxial graphene Hall bars covered by SiO(2) that the measured carrier density is strongly inhomogenous and predominantly induced by charged impurities at the grapheme/dielectric interface that limit mobility via Coulomb interactions. Our work emphasizes that material integration of epitaxial graphene and a gate dielectric is the next major road block towards the realization of graphene-based electronics. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3607284] C1 [Puls, Conor P.; Staley, Neal E.; Liu, Ying] Penn State Univ, Dept Phys, University Pk, PA 16802 USA. [Moon, Jeong-Sun] HRL Labs, Malibu, CA 90265 USA. [Robinson, Joshua A.] Penn State Univ, Ctr Electroopt, University Pk, PA 16802 USA. [Tedesco, Joseph L.; Myers-Ward, Rachael L.; Eddy, Charles R., Jr.; Gaskill, D. Kurt] USN, Res Lab, Adv SiC Epitaxial Res Lab, Washington, DC 20375 USA. RP Puls, CP (reprint author), Penn State Univ, Dept Phys, 104 Davey Lab, University Pk, PA 16802 USA. EM liu@phys.psu.edu RI Robinson, Joshua/I-1803-2012 FU DARPA; ASEE; ONR FX This work was supported by DARPA under the CERA program. Some devices were fabricated at the PSU MRI Nanofab within the NNIN under Cooperative Agreement No. 0335765. J.L.T. acknowledges postdoctoral fellowship support from ASEE. Portions of work at NRL were supported by ONR. The views, opinions, and findings contained in this article are those of the authors and should not be interpreted as representing the official views or policies, either expressed or implied, of DARPA or DOD. NR 21 TC 3 Z9 3 U1 1 U2 21 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD JUL 4 PY 2011 VL 99 IS 1 AR 013103 DI 10.1063/1.3607284 PG 3 WC Physics, Applied SC Physics GA 791CN UT WOS:000292639200054 ER PT J AU Radko, T AF Radko, Timour TI Eddy viscosity and diffusivity in the modon-sea model SO JOURNAL OF MARINE RESEARCH LA English DT Article ID OCEAN CIRCULATION MODELS; STRATIFIED KOLMOGOROV FLOW; BETA-PLANE; 2-DIMENSIONAL TURBULENCE; OVERTURNING CIRCULATION; BAROCLINIC INSTABILITY; DEEP STRATIFICATION; 3-DIMENSIONAL FLOW; MESOSCALE EDDIES; CELLULAR FLOWS AB A deterministic model is developed to evaluate and explain the rate of dissipation of momentum in eddying oceanic flows. Theory is based on a classical conceptualization of mesoscale variability - Stern's modon-sea solution - which represents a closely packed array of steady compact dipolar vortices on the barotropic beta-plane. In our model, the periodic modon-sea pattern is subjected to a large-scale perturbation, weakly modulating the amplitude of the individual modons. The asymptotic multiscale analysis makes it possible to explicitly describe the interaction between the modon-sea eddies and the perturbing flow. This interaction results in a systematic weakening of the large-scale perturbation. The eddy viscosity in the model is found to be only weakly dependent on the explicit dissipation but rapidly decreases with increased separation of the modons. The estimates based on the modon-sea model are comparable to, but less than, the values of viscosity typically used in coarse resolution numerical ocean models. The eddy diffusivity of passive tracers is also evaluated and discussed in terms of a combination of analytical and numerical methods. The asymptotic theories are successfully tested by direct numerical simulations. C1 USN, Postgrad Sch, Dept Oceanog, Monterey, CA 93943 USA. RP Radko, T (reprint author), USN, Postgrad Sch, Dept Oceanog, Monterey, CA 93943 USA. EM tradko@nps.edu FU National Science Foundation [OCE 0623524] FX The author is indebted forever to his former mentor Melvin Stern for his generous help and guidance. The analysis in this paper follows directly from Stern's pioneering insights into the dynamics of oceanic vortices. Thanks are in order to Jason Flanagan, Igor Kamenkovich, David Marshall, George Veronis and reviewers for helpful comments. Support of the National Science Foundation (grant OCE 0623524) is gratefully acknowledged. NR 82 TC 2 Z9 2 U1 0 U2 4 PU SEARS FOUNDATION MARINE RESEARCH PI NEW HAVEN PA YALE UNIV, KLINE GEOLOGY LAB, 210 WHITNEY AVENUE, NEW HAVEN, CT 06520-8109 USA SN 0022-2402 J9 J MAR RES JI J. Mar. Res. PD JUL-NOV PY 2011 VL 69 IS 4-6 BP 723 EP 752 PG 30 WC Oceanography SC Oceanography GA 909KB UT WOS:000301562300014 ER PT J AU Simeonov, JA AF Simeonov, Julian A. TI Primary and secondary intrusions in double-diffusively stable vertical gradients SO JOURNAL OF MARINE RESEARCH LA English DT Article ID THERMOHALINE INTRUSIONS; SALT FINGERS; HORIZONTAL GRADIENTS; INDIAN-OCEAN; SHEAR-FLOW; INSTABILITIES; WATER; MODEL AB The purpose of this paper is to show that molecularly-driven double-diffusive intrusions can produce significant lateral and vertical double-diffusive mixing even when the initial temperature and salinity are both stably stratified in the vertical. Assuming uniform density-compensated horizontal gradients and periodic disturbances, three-dimensional direct numerical simulations (DNS) for the fastest growing intrusion show that the latter equilibrates due to the generation of salt fingers which reduce the driving buoyancy pressure gradient. The DNS also provided statistical data for a new parameterization of the salt finger fluxes which includes the effects of shear and variable vertical gradients. This parameterization makes it feasible to numerically investigate the subharmonic instabilities of the equilibrium DNS solution. Linearized calculations with parameterized salt fingers show that the vertical and horizontal wavelength of the fastest growing secondary instability are approximately three and fourteen times that of the primary intrusion. Nonlinear simulations show that the equilibrium lateral and vertical double-diffusive fluxes of the secondary mode are an order of magnitude larger than those of the primary intrusion. Numerically determined dependences of the intrusion lateral velocity on the vertical wavelength are compared to previous numerical and experimental work. C1 USN, Res Lab, Marine Geosci Div, Stennis Space Ctr, MS 39529 USA. RP Simeonov, JA (reprint author), USN, Res Lab, Marine Geosci Div, Stennis Space Ctr, MS 39529 USA. EM simeonov@nrlssc.navy.mil OI Simeonov, Julian/0000-0002-7554-071X FU National Science Foundation [OCE-0236304]; Office of Naval Research FX This work began at Florida State University and was completed at the Naval Research Laboratory. I gratefully acknowledge the support of the National Science Foundation under Grant OCE-0236304 and the support of the Office of Naval Research to the Naval Research Laboratory via the Jerome and Isabella Karle Distinguished Scholar Fellowship Program. Computing resources were provided by the San Diego Supercomputer Center. The paper has improved thanks to comments by Barry Ruddick and an anonymous reviewer. I am also grateful to my mentor, Melvin Stern, for his guidance and support. I greatly miss his friendship, dedication and collaboration. NR 28 TC 0 Z9 0 U1 0 U2 4 PU SEARS FOUNDATION MARINE RESEARCH PI NEW HAVEN PA YALE UNIV, KLINE GEOLOGY LAB, 210 WHITNEY AVENUE, NEW HAVEN, CT 06520-8109 USA SN 0022-2402 J9 J MAR RES JI J. Mar. Res. PD JUL-NOV PY 2011 VL 69 IS 4-6 BP 797 EP 825 PG 29 WC Oceanography SC Oceanography GA 909KB UT WOS:000301562300017 ER PT J AU Wheeler, B AF Wheeler, Brannon TI The Birth of the Prophet Muhammad: Devotional Piety in Sunni Islam SO JOURNAL OF THE AMERICAN ORIENTAL SOCIETY LA English DT Book Review C1 [Wheeler, Brannon] USN Acad, Annapolis, MD 21402 USA. RP Wheeler, B (reprint author), USN Acad, Annapolis, MD 21402 USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU AMER ORIENTAL SOC PI ANN ARBOR PA HARLAN HATCHER GRADUATE LIB UNIV MICHIGAN, ANN ARBOR, MI 48109-1205 USA SN 0003-0279 J9 J AM ORIENTAL SOC JI J. Am. Orient. Soc. PD JUL-SEP PY 2011 VL 131 IS 3 BP 507 EP 507 PG 1 WC Asian Studies SC Asian Studies GA 867OB UT WOS:000298462600027 ER PT J AU May, L Porter, C Tribble, D Armstrong, A Mostafa, M Riddle, M AF May, Larissa Porter, Chad Tribble, David Armstrong, Adam Mostafa, Manal Riddle, Mark TI Self-reported incidence of skin and soft tissue infections among deployed US military SO TRAVEL MEDICINE AND INFECTIOUS DISEASE LA English DT Article DE Skin and soft tissue infections; Military; Deployment ID RESISTANT STAPHYLOCOCCUS-AUREUS; METHICILLIN-RESISTANT; AFGHANISTAN; IRAQ; COLONIZATION; SOLDIERS; TROOPS; POPULATION; PERSONNEL; RECRUITS AB The incidence of skin and soft tissue infections has steadily increased over the Skin and soft tissue past decade, and military populations, particularly recruits, have been affected. However, infections; the epidemiology of skin and soft tissue infections in deployed personnel has not previously Military; been described. Deployment We conducted a cross-sectional study of United States military personnel in mid-deployment using self-reported questionnaire data containing 11 demographic questions and 20 questions related to skin and soft tissue infections. The primary outcome was self-reported incident SSTI. Descriptive analyses were conducted and incidence estimates calculated. Multivariable regression models were developed to evaluate the association between SSTI and important covariates. Self-reported treatment modalities and effect on work performance were also assessed. The study was approved by the Institutional Review Board. 2125 questionnaires were completed over 12 months using convenience sampling. 110 personnel (5%) reported one or more skin and soft tissue infection during their most recent employment, for an incidence of 52 cases per 100,000 person-days. The majority reported a single infection. A higher proportion of individuals reporting skin and soft tissue infection were female, reported antibiotic use in the 6 months prior to completing the survey, had a family member in the healthcare occupation, and were senior enlisted or officers. 40 (36%) were treated with antibiotics and 24 (22%) underwent incision and drainage. Less than 5% (3 patients) required admission. Eighty eight respondents (81%), reported no days of lost job performance. There is a higher than expected incidence of skin and soft tissue infections in deployed military personnel. Although fewer than 20% of patients report missing at least one day of work, this can have a significant impact on the military mission. Further study should be conducted into how to prevent skin and soft tissue infections in military populations. (C) 2011 Elsevier Ltd. All rights reserved. C1 [May, Larissa] George Washington Univ, Dept Emergency Med, Washington, DC 20037 USA. [Porter, Chad; Riddle, Mark] USN, Enter Dis Dept, Med Res Ctr, Silver Spring, MD USA. [Tribble, David] Uniformed Serv Univ Hlth Sci, Dept Prevent Med & Biometr, Infect Dis Clin Res Program, Bethesda, MD 20815 USA. [Armstrong, Adam] Natl Naval Med Ctr, Navy Cent HIV Program, Bethesda, MD 20889 USA. [Mostafa, Manal] US Naval Med Res Unit 3, Cairo, Egypt. [Mostafa, Manal] Clin Trial & Mil Surveys Program CTMS, Abbasiya, Egypt. RP May, L (reprint author), George Washington Univ, Dept Emergency Med, 2150 Penn Ave NW,Suite 2B, Washington, DC 20037 USA. EM larissa.may@gmail.com; Chad.Porter@med.navy.mil; dtribble@usuhs.mil; Adam.Armstrong@med.navy.mil; Manal.Mostafa.eg@med.navy.mil; mark.riddle.mil@ah20.navy.mil RI Valle, Ruben/A-7512-2013 NR 34 TC 7 Z9 7 U1 0 U2 2 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 1477-8939 J9 TRAVEL MED INFECT DI JI Travel Med. Infect. Dis. PD JUL PY 2011 VL 9 IS 4 BP 213 EP 220 DI 10.1016/j.tmaid.2011.06.001 PG 8 WC Public, Environmental & Occupational Health; Infectious Diseases SC Public, Environmental & Occupational Health; Infectious Diseases GA 854WH UT WOS:000297525000006 PM 21917525 ER PT J AU Whitbeck, ER Quinn, GD Quinn, JB AF Whitbeck, Evan R. Quinn, George D. Quinn, Janet B. TI Effect of Calcium Hydroxide on the Fracture Resistance of Dentin SO JOURNAL OF RESEARCH OF THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY LA English DT Article DE calcium hydroxide; edge chipping; fracture resistance; human dentin; pulpectomy; teeth ID SODIUM-HYPOCHLORITE; ROOT DENTIN; EDGE-STRENGTH; TOUGHNESS; CERAMICS; GEOMETRY; MODULUS; TISSUE; TEETH AB An increased incidence of fracture has been reported in teeth where root canals were treated with calcium hydroxide. Edge chipping is one test used to measure the resistance of brittle materials to fracture. Presently, no studies have reported on edge chipping in teeth. This study evaluated the fracture resistance of human dentin exposed to calcium hydroxide for up to 60 days using the edge chipping method. Twelve recently extracted teeth were divided into a control group and three experimental groups with varying calcium hydroxide exposures. All teeth underwent pulpectomy via standard protocol. It was expected that the edge chip resistance would decrease as a function of exposure, but the results showed the converse. Chip resistance may reflect both the fracture resistance and the hardness of dentin, a quasi brittle material. C1 [Whitbeck, Evan R.] USN, Comprehens Dent Dept, Sch Postgrad Dent, Bethesda, MD 20889 USA. [Quinn, George D.; Quinn, Janet B.] Natl Inst Stand & Technol, Amer Dent Assocoat Fdn, Paffenbarger Res Ctr, Gaithersburg, MD 20899 USA. RP Whitbeck, ER (reprint author), USN, Comprehens Dent Dept, Sch Postgrad Dent, Bethesda, MD 20889 USA. EM whitbeck.evan@gmail.com; george.quinn@nist.gov FU National Institute of Standards and Technology; National Institute of Health [R01-DE17983] FX The authors appreciate support of the National Institute of Standards and Technology, and from National Institute of Health Grant R01-DE17983, which made this work possible. NR 43 TC 8 Z9 8 U1 2 U2 8 PU US GOVERNMENT PRINTING OFFICE PI WASHINGTON PA SUPERINTENDENT DOCUMENTS,, WASHINGTON, DC 20402-9325 USA SN 1044-677X J9 J RES NATL INST STAN JI J. Res. Natl. Inst. Stand. Technol. PD JUL-AUG PY 2011 VL 116 IS 4 BP 743 EP 749 DI 10.6028/jres.116.017 PG 7 WC Instruments & Instrumentation; Physics, Applied SC Instruments & Instrumentation; Physics GA 832NH UT WOS:000295811200004 PM 26989596 ER PT J AU Shi, Y Hou, YT Kompella, S Sherali, HD AF Shi, Yi Hou, Y. Thomas Kompella, Sastry Sherali, Hanif D. TI Maximizing Capacity in Multihop Cognitive Radio Networks under the SINR Model SO IEEE TRANSACTIONS ON MOBILE COMPUTING LA English DT Article DE Theory; multihop cognitive radio network; nonlinear optimization; SINR model; cross-layer; capacity ID WIRELESS NETWORKS AB Cognitive radio networks (CRNs) have the potential to utilize spectrum efficiently and are positioned to be the core technology for the next-generation multihop wireless networks. An important problem for such networks is its capacity. We study this problem for CRNs in the SINR (signal-to-interference-and-noise-ratio) model, which is considered to be a better characterization of interference (but also more difficult to analyze) than disk graph model. The main difficulties of this problem are two-fold. First, SINR is a nonconvex function of transmission powers; an optimization problem in the SINR model is usually a nonconvex program and NP-hard in general. Second, in the SINR model, scheduling feasibility and the maximum allowed flow rate on each link are determined by SINR at the physical layer. To maximize capacity, it is essential to follow a cross-layer approach, but joint optimization at physical (power control), link (scheduling), and network (flow routing) layers with the SINR function is inherently difficult. In this paper, we give a mathematical characterization of the joint relationship among these layers. We devise a solution procedure that provides a (1 - epsilon) optimal solution to this complex problem, where epsilon is the required accuracy. Our theoretical result offers a performance benchmark for any other algorithms developed for practical implementation. Using numerical results, we demonstrate the efficacy of the solution procedure and offer quantitative understanding on the interaction of power control, scheduling, and flow routing in a CRN. C1 [Shi, Yi; Hou, Y. Thomas] Virginia Polytech Inst & State Univ, Bradley Dept Elect & Comp Engn, Blacksburg, VA 24061 USA. [Kompella, Sastry] USN, Res Lab, Div Informat Technol, Washington, DC 20375 USA. [Sherali, Hanif D.] Virginia Polytech Inst & State Univ, Grado Dept Ind & Syst Engn, Blacksburg, VA 24061 USA. RP Shi, Y (reprint author), Virginia Polytech Inst & State Univ, Bradley Dept Elect & Comp Engn, 302 Whittemore Hall,0111, Blacksburg, VA 24061 USA. EM yshi@vt.edu; thou@vt.edu; sastry.kompella@nrl.navy.mil; hanifs@vt.edu FU US National Science Foundation (NSF) [CNS-0721570]; US Naval Research Lab [N00173-10-1-G-007]; ONR; NSF [CMMI-0969169] FX The authors thank the anonymous reviewers for their constructive comments that helped improve the paper. The authors also thank editor Thyaga Nandagopal for his guidance in their revision efforts and his prompt handling of the review process. The work of Y.T. Hou and Y. Shi was supported in part by US National Science Foundation (NSF) Grant CNS-0721570 and US Naval Research Lab Grant N00173-10-1-G-007. The work of S. Kompella was supported in part by the ONR. The work of H.D. Sherali was supported in part by NSF Grant CMMI-0969169. NR 34 TC 46 Z9 53 U1 2 U2 6 PU IEEE COMPUTER SOC PI LOS ALAMITOS PA 10662 LOS VAQUEROS CIRCLE, PO BOX 3014, LOS ALAMITOS, CA 90720-1314 USA SN 1536-1233 EI 1558-0660 J9 IEEE T MOBILE COMPUT JI IEEE. Trans. Mob. Comput. PD JUL PY 2011 VL 10 IS 7 BP 954 EP 967 DI 10.1109/TMC.2010.204 PG 14 WC Computer Science, Information Systems; Telecommunications SC Computer Science; Telecommunications GA 764XQ UT WOS:000290668400004 ER PT J AU Razzaque, S Smirnov, AY AF Razzaque, Soebur Smirnov, A. Yu TI Searching for sterile neutrinos in ice SO JOURNAL OF HIGH ENERGY PHYSICS LA English DT Article DE Neutrino Physics; Solar and Atmospheric Neutrinos ID ATMOSPHERIC NEUTRINOS; MASS HIERARCHY; OSCILLATIONS; MATTER; EARTH; LSND AB Oscillation interpretation of the results from the LSND, MiniBooNE and some other experiments requires existence of sterile neutrino with mass similar to 1 eV and mixing with the active neutrinos vertical bar U-mu 0 vertical bar(2) similar to (0.02 - 0.04). It has been realized some time ago that existence of such a neutrino affects significantly the fluxes of atmospheric neutrinos in the TeV range which can be tested by the IceCube Neutrino Observatory. In view of the first IceCube data release we have revisited the oscillations of high energy atmospheric neutrinos in the presence of one sterile neutrino. Properties of the oscillation probabilities are studied in details for various mixing schemes both analytically and numerically. The energy spectra and angular distributions of the nu mu-events have been computed for the simplest nu(s) - mass, and nu(s) - nu(mu) mixing schemes and confronted with the IceCube data. An illustrative statistical analysis of the present data shows that in the nu(s) - mass mixing case the sterile neutrinos with parameters required by LSND/MiniBooNE can be excluded at about 3 sigma level. The nu(s) - nu mu mixing scheme, however, can not be ruled out with currently available IceCube data. C1 [Razzaque, Soebur] George Mason Univ, Coll Sci, Fairfax, VA 22030 USA. [Smirnov, A. Yu] Abdus Salam Int Ctr Theoret Phys, I-34100 Trieste, Italy. RP Razzaque, S (reprint author), USN, Res Lab, Div Space Sci, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM srazzaqu@gmu.edu; smirnov@ictp.it FU U.S. Naval Research Laboratory FX We thank Doug Cowen, Kara Hoffman, Paolo Desiati, Elisa Resconi and specially Warren Huelsnitz for helping us understand the IceCube results better. Work of S.R. was funded while under contract with the U.S. Naval Research Laboratory. NR 43 TC 20 Z9 20 U1 0 U2 1 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1029-8479 J9 J HIGH ENERGY PHYS JI J. High Energy Phys. PD JUL PY 2011 IS 7 AR 084 DI 10.1007/JHEP07(2011)084 PG 36 WC Physics, Particles & Fields SC Physics GA 805PN UT WOS:000293741500020 ER PT J AU Kraska, J AF Kraska, James TI Shipping Interdiction and the Law of the Sea SO AMERICAN JOURNAL OF INTERNATIONAL LAW LA English DT Book Review C1 [Kraska, James] USN, War Coll, Int Law Dept, Newport, RI 02841 USA. RP Kraska, J (reprint author), USN, War Coll, Int Law Dept, Newport, RI 02841 USA. NR 11 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC INT LAW PI WASHINGTON PA 2223 MASSACHUSETTS AVE N W, WASHINGTON, DC 20008-2864 USA SN 0002-9300 J9 AM J INT LAW JI Am. J. Int. Law PD JUL PY 2011 VL 105 IS 3 BP 638 EP 643 PG 6 WC International Relations; Law SC International Relations; Government & Law GA 809XG UT WOS:000294089400029 ER PT J AU Tank, SE Lesack, LFW Gareis, JAL Osburn, CL Hesslein, RH AF Tank, Suzanne E. Lesack, Lance F. W. Gareis, Jolie A. L. Osburn, Christopher L. Hesslein, Ray H. TI Multiple tracers demonstrate distinct sources of dissolved organic matter to lakes of the Mackenzie Delta, western Canadian Arctic SO LIMNOLOGY AND OCEANOGRAPHY LA English DT Article ID FRESH-WATER; STABLE-ISOTOPES; BACTERIAL-GROWTH; FOOD WEBS; CARBON; FLUORESCENCE; MACROPHYTE; FLOODPLAIN; DEGRADATION; RESPONSES AB Lakes of the Mackenzie Delta occur across a gradient that contains three clear end members: those that remain connected to river-water channels throughout the summer; those that receive only brief inputs of river water during an annual spring flood but contain dense macrophyte stands; and those that experience significant permafrost thaw along their margins. We measured dissolved organic carbon (DOC) concentration, dissolved organic matter (DOM) absorption and fluorescence, and stable isotopes of DOM, DOM precursor materials, and bacteria to elucidate the importance of river water, macrophytes, and thermokarst as DOM sources to Mackenzie Delta lakes. Despite standing stocks of macrophyte C that are sevenfold to 12-fold greater than those of total DOC, stable isotopes indicated that autochthonous sources contributed less than 15% to overall DOM in macrophyte-rich lakes. Instead, fluorescence and absorption indicated that the moderate summertime increase in DOC concentration in macrophyte-rich lakes was the result of infrequent flushing, while bacterial delta(13)C indicated rapid bacterial removal of autochthonous DOC from the water column. In thermokarst lakes, summertime increases in DOC concentration were substantial, and stable isotopes indicated that much of this increase came from C released as a result of thermokarst-related processes. Our results indicate that these distinct sources of DOM to neighboring arctic Delta lakes may drive between-lake differences in C cycling and energy flow. Rapidly assimilated macrophyte DOM should be an important contributor to microbial food webs in our study lakes. In contrast, the accumulation of thermokarst-origin DOM allows for a significant role in physico-chemistry but indicates a lesser contribution of this DOM to higher trophic levels. C1 [Tank, Suzanne E.; Lesack, Lance F. W.] Simon Fraser Univ, Dept Biol Sci, Burnaby, BC V5A 1S6, Canada. [Lesack, Lance F. W.; Gareis, Jolie A. L.] Simon Fraser Univ, Dept Geog, Burnaby, BC V5A 1S6, Canada. [Osburn, Christopher L.] USN, Res Lab, Div Chem, Washington, DC 20375 USA. [Hesslein, Ray H.] Fisheries & Oceans Canada, Inst Freshwater, Winnipeg, MB R3T 2N6, Canada. RP Tank, SE (reprint author), Marine Biol Lab, Ctr Ecosyst, Woods Hole, MA 02543 USA. EM setank@mbl.edu RI Tank, Suzanne/I-4816-2012; OI Tank, Suzanne/0000-0002-5371-6577; Osburn, Christopher/0000-0002-9334-4202 FU Natural Sciences and Engineering Research Council of Canada (NSERC); Science Horizons Youth Internship Program; Northern Scientific Training Program; NSERC; Simon Fraser University; Garfield Weston Award for Northern Research FX We gratefully acknowledge the technical assistance of Adam Chateauvert and thank the Inuvialuit and Gwich'in community organizations for allowing this work to occur within their traditional territories. This study was supported by a Discovery Grant and Northern Research Supplement from the Natural Sciences and Engineering Research Council of Canada (NSERC) to L. F. W. L.; funds from the Science Horizons Youth Internship Program, Northern Scientific Training Program, and NSERC Northern Research Internship; and logistical support from the Aurora Research Institute and Polar Continental Shelf Project. Personal financial support to S. E. T. was provided by a Simon Fraser University CD Nelson Memorial Graduate Scholarship, an NSERC Canada Graduate Scholarship-Doctoral, and a Garfield Weston Award for Northern Research. Thoughtful comments from two anonymous reviewers greatly improved the manuscript. NR 57 TC 20 Z9 21 U1 0 U2 39 PU AMER SOC LIMNOLOGY OCEANOGRAPHY PI WACO PA 5400 BOSQUE BLVD, STE 680, WACO, TX 76710-4446 USA SN 0024-3590 J9 LIMNOL OCEANOGR JI Limnol. Oceanogr. PD JUL PY 2011 VL 56 IS 4 BP 1297 EP 1309 DI 10.4319/lo.2011.56.4.1297 PG 13 WC Limnology; Oceanography SC Marine & Freshwater Biology; Oceanography GA 816LZ UT WOS:000294603400010 ER PT J AU McKenna, TM AF McKenna, Thomas M. TI Developing Bioinspired Autonomous Systems SO MARINE TECHNOLOGY SOCIETY JOURNAL LA English DT Editorial Material ID INSECT FLIGHT; LOCOMOTION; DYNAMICS C1 Off Naval Res, Div Human & Bioengn Syst, Arlington, VA 22203 USA. RP McKenna, TM (reprint author), Off Naval Res, Div Human & Bioengn Syst, 875 N Randolph St,Suite 1425, Arlington, VA 22203 USA. EM tom.mckenna@navy.mil NR 23 TC 5 Z9 5 U1 0 U2 5 PU MARINE TECHNOLOGY SOC INC PI COLUMBIA PA 5565 STERRETT PLACE, STE 108, COLUMBIA, MD 21044 USA SN 0025-3324 EI 1948-1209 J9 MAR TECHNOL SOC J JI Mar. Technol. Soc. J. PD JUL-AUG PY 2011 VL 45 IS 4 BP 19 EP 23 PG 5 WC Engineering, Ocean; Oceanography SC Engineering; Oceanography GA 818GD UT WOS:000294738700004 ER PT J AU Geder, JD Palmisano, JS Ramamurti, R Pruessner, M Ratna, B Sandberg, WC AF Geder, Jason D. Palmisano, John S. Ramamurti, Ravi Pruessner, Marius Ratna, Banahalli Sandberg, William C. TI Bioinspired Design Process for an Underwater Flying and Hovering Vehicle SO MARINE TECHNOLOGY SOCIETY JOURNAL LA English DT Article DE bio-inspired robotics; pectoral fin; unmanned systems; computational fluid dynamics ID FLAPPING AQUATIC FLIGHT; GOMPHOSUS-VARIUS; LABRID FISHES; BIRD WRASSE; LOCOMOTION; VISUALIZATION; COMPUTATIONS; PROPULSION; KINEMATICS; DYNAMICS AB We review here the results obtained during the past several years in a series of computational and experimental investigations aimed at understanding the origin of high-force production in the flapping wings of insects and the flapping and deforming fins of fish and the incorporation of that information into bioinspired vehicle designs. We summarize the results obtained on pectoral fin force production, flapping and deforming fin design, and the emulation of fish pectoral fin swimming in unmanned vehicles. In particular, we discuss the main results from the computational investigations of pectoral fin force production for a particular coral reef fish, the bird wrasse (Gomphosus varius), whose impressive underwater flight and hovering performance matches our vehicle mission requirements. We describe the tradeoffs made between performance and produceability during the bio-inspired design of an actively controlled curvature pectoral fin and the incorporation of it into two underwater flight vehicles: a two-fin swimming version and four-fin swimming version. We describe the unique computational approach taken throughout the fin and vehicle design process for relating fin deformation time-histories to specified desired vehicle dynamic behaviors. We describe the development of the vehicle controller, including hardware implementation, using actuation of the multiple deforming flapping fins as the only means of propulsion and control. Finally, we review the comparisons made to date between four-fin vehicle experimental trajectory measurements and controller simulation predictions and discuss the incorporation of those comparisons into the controller design. C1 [Geder, Jason D.] USN, Res Lab, Computat Phys & Fluid Dynam Lab, Washington, DC 20375 USA. [Sandberg, William C.] Sci Applicat Int Corp, Mclean, VA 22102 USA. RP Geder, JD (reprint author), USN, Res Lab, Computat Phys & Fluid Dynam Lab, Overlook Ave SW, Washington, DC 20375 USA. EM jgeder@lcp.nrl.navy.mil NR 40 TC 0 Z9 0 U1 1 U2 11 PU MARINE TECHNOLOGY SOC INC PI COLUMBIA PA 5565 STERRETT PLACE, STE 108, COLUMBIA, MD 21044 USA SN 0025-3324 J9 MAR TECHNOL SOC J JI Mar. Technol. Soc. J. PD JUL-AUG PY 2011 VL 45 IS 4 BP 74 EP 82 PG 9 WC Engineering, Ocean; Oceanography SC Engineering; Oceanography GA 818GD UT WOS:000294738700010 ER PT J AU Fish, FE Weber, PW Murray, MM Howle, LE AF Fish, Frank E. Weber, Paul W. Murray, Mark M. Howle, Laurens E. TI Marine Applications of the Biomimetic Humpback Whale Flipper SO MARINE TECHNOLOGY SOCIETY JOURNAL LA English DT Article DE tubercles; delayed stall; Megaptera novaeangliae; leading edge; bio-inspired design ID LEADING-EDGE PROTUBERANCES; MEGAPTERA-NOVAEANGLIAE; DRAG REDUCTION; PERFORMANCE; TUBERCLES; TECHNOLOGY; LOCOMOTION; PROPELLER; DOLPHIN AB The biomimetic approach seeks technological advancement through a transfer of technology from natural technologies to engineered systems. The morphology of the wing-like flipper of the humpback whale has potential for marine applications. As opposed to the straight leading edge of conventional hydrofoils, the humpback whale flipper has a number of sinusoid-like rounded bumps, called tubercles, which are arranged periodically along the leading edge. The presence of the tubercles modifies the water flow over the wing-like surface, creating regions of vortex generation between the tubercles. These vortices interact with the flow over the tubercle and accelerate that flow, helping to maintain a partially attached boundary layer. This hydrodynamic effect can delay stall to higher angles of attack, increases lift, and reduces drag compared to the post-stall condition of conventional wings. As the humpback whale functions in the marine environment in a Reynolds regime similar to some engineered marine systems, the use of tubercles has the potential to enhance the performance of wing-like structures. Specific applications of the tubercles for marine technology include sailboat masts, fans, propellers, turbines; and control surfaces, such as rudders, dive planes, stabilizers, spoilers, and keels. C1 [Fish, Frank E.] W Chester Univ, Dept Biol, W Chester, PA 19383 USA. [Murray, Mark M.] USN Acad, Annapolis, MD 21402 USA. [Howle, Laurens E.] Duke Univ, Durham, NC 27706 USA. RP Fish, FE (reprint author), W Chester Univ, Dept Biol, W Chester, PA 19383 USA. EM ffish@wcupa.edu FU National Science Foundation [IOS-0640185]; National Defense Science and Engineering Graduate (NDSEG) FX We thank the technical support staff of the United States Naval Academy. This work was supported by the National Science Foundation (IOS-0640185) to FEF and the National Defense Science and Engineering Graduate (NDSEG) Fellowship to PWW. NR 51 TC 3 Z9 3 U1 1 U2 29 PU MARINE TECHNOLOGY SOC INC PI COLUMBIA PA 5565 STERRETT PLACE, STE 108, COLUMBIA, MD 21044 USA SN 0025-3324 EI 1948-1209 J9 MAR TECHNOL SOC J JI Mar. Technol. Soc. J. PD JUL-AUG PY 2011 VL 45 IS 4 BP 198 EP 207 PG 10 WC Engineering, Ocean; Oceanography SC Engineering; Oceanography GA 818GD UT WOS:000294738700020 ER PT J AU Nguyen, HD Galitz, MS Clarke, DD AF Nguyen, Huong D. Galitz, Michael S. Clarke, Douglas D. TI What is the diagnosis? Cavernous hemangioma SO ENDOCRINE PRACTICE LA English DT Editorial Material ID MALFORMATIONS C1 [Nguyen, Huong D.; Galitz, Michael S.; Clarke, Douglas D.] Naval Med Ctr Portsmouth, Div Endocrinol, Portsmouth, VA USA. RP Nguyen, HD (reprint author), USN, Div Endocrinol, Med Ctr Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA 23708 USA. EM huong.nguyen@med.navy.mil NR 3 TC 0 Z9 0 U1 0 U2 0 PU AMER ASSOC CLINICAL ENDOCRINOLOGISTS PI JACKSONVILLE PA 245 RIVERSIDE AVENUE, STE 200, JACKSONVILLE, FL 32202 USA SN 1530-891X J9 ENDOCR PRACT JI Endocr. Pract. PD JUL-AUG PY 2011 VL 17 IS 4 BP 667 EP 667 DI 10.4158/EP11021.VV PG 1 WC Endocrinology & Metabolism SC Endocrinology & Metabolism GA 812FH UT WOS:000294276000025 PM 21324810 ER PT J AU Polak, S Riddle, MS Tribble, DR Armstrong, AW Mostafa, M Porter, CK AF Polak, Suzanne Riddle, Mark S. Tribble, David R. Armstrong, Adam W. Mostafa, Manal Porter, Chad K. TI Pre-deployment vaccinations and perception of risk among US military personnel SO HUMAN VACCINES LA English DT Article DE vaccine; attitudes; perception; compulsory; military ID COMPULSORY VACCINATION; ATTITUDES; PARENTS; TROOPS AB Background: Vaccination programs have significantly reduced the incidence of numerous infectious diseases; however, public attitudes toward immunization oftentimes remain contentious. Concerns over vaccine safety and effectiveness, compounded with reduced perceived risk of disease, influence decision making and frequently override public health recommendations. Although vaccinations are compulsory for US military personnel, their concerns mirror the general population, resulting in sub-optimal coverage. Results: Demographics of the 1,757 respondents: 83.3% male, 71.1% Army, 87.5% enlisted, mean age of 29.2 years (standard deviation: 8.3). The majority (89.3%) reported receiving all pre-deployment vaccines; 17.1% stated they would decline if given the opportunity. Factors associated with an increased likelihood of declining vaccines included a perception that the vaccines were not safe [odds ratio (OR): 3.7; p < 0.001] and rarely/never believing information from the military command (OR: 2.2; p < 0.001). Those with a perceived risk for the diseases targeted by the vaccines were less likely to decline (OR: 0.6; p < 0.001). Discussion: In US military personnel, negative perceptions of pre-deployment vaccines exist. These attitudes appear to be associated with negative perceptions of vaccine safety and low perceived disease risk. Targeted interventions, focusing on the drivers of negative perceptions toward vaccines, and accounting for the source of the educational material, may influence attitudes and improve vaccination perceptions. Methods: A self-administered questionnaire was completed by a convenience sample of US military personnel deployed to Iraq, Afghanistan and surrounding regions. Questions solicited demographic information and assessed agreement with statements in an attempt to identify factors associated with declining pre-deployment vaccines. C1 [Riddle, Mark S.; Porter, Chad K.] USN, Med Res Ctr, Enter Dis Dept, Silver Spring, MD USA. [Polak, Suzanne] Uniformed Serv Univ Hlth Sci, Dept Prevent Med & Biometr, Bethesda, MD 20814 USA. [Tribble, David R.] Uniformed Serv Univ Hlth Sci, Infect Dis Clin Res Program, Bethesda, MD 20814 USA. [Armstrong, Adam W.; Mostafa, Manal] Naval Med Res Unit 3, Cairo, Egypt. RP Porter, CK (reprint author), USN, Med Res Ctr, Enter Dis Dept, Silver Spring, MD USA. EM Chad.Porter@med.navy.mil RI Riddle, Mark/A-8029-2011; Valle, Ruben/A-7512-2013 FU [6000.RAD1.D.E0301] FX This work was funded by work unit number 6000.RAD1.D.E0301. NR 17 TC 3 Z9 3 U1 1 U2 6 PU LANDES BIOSCIENCE PI AUSTIN PA 1806 RIO GRANDE ST, AUSTIN, TX 78702 USA SN 1554-8600 J9 HUM VACCINES JI Hum. Vaccines PD JUL PY 2011 VL 7 IS 7 BP 762 EP 767 DI 10.4161/hv.7.7.15574 PG 6 WC Biotechnology & Applied Microbiology; Immunology SC Biotechnology & Applied Microbiology; Immunology GA 814LC UT WOS:000294453300015 PM 21712646 ER PT J AU del Pozo, M Manuel, C Gonzalez-Aranguena, E Owen, G AF del Pozo, Monica Manuel, Conrado Gonzalez-Arangueena, Enrique Owen, Guillermo TI Centrality in directed social networks. A game theoretic approach SO SOCIAL NETWORKS LA English DT Article DE Social networks; Game theory; Centrality; Shapley value ID COOPERATIVE GAMES; SHAPLEY VALUE; POWER; INDEX; FLOW AB In this paper we define a family of centrality measures for directed social networks from a game theoretical point of view. We follow the line started in our previous paper (Gomez et al., 2003) and, besides the definition, we obtain a characterization of the measures and an additive decomposition in three summands that can be interpreted in terms of emission, betweenness and reception centrality components. (C) 2011 Elsevier B.V. All rights reserved. C1 [del Pozo, Monica; Manuel, Conrado; Gonzalez-Arangueena, Enrique] Univ Complutense Madrid, Escuela Univ Estadist, Dpto Estadist & IO 3, Madrid, Spain. [Owen, Guillermo] USN, Postgrad Sch, Dept Math, Monterey, CA 93943 USA. RP Manuel, C (reprint author), Univ Complutense Madrid, Escuela Univ Estadist, Dpto Estadist & IO 3, Madrid, Spain. EM conrado@estad.ucm.es RI Manuel, Conrado/I-1958-2015; del Pozo, Monica/I-2183-2015; Gonzalez-Aranguena, Enrique/L-8359-2014 NR 41 TC 7 Z9 7 U1 0 U2 11 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0378-8733 EI 1879-2111 J9 SOC NETWORKS JI Soc. Networks PD JUL PY 2011 VL 33 IS 3 BP 191 EP 200 DI 10.1016/j.socnet.2011.04.001 PG 10 WC Anthropology; Sociology SC Anthropology; Sociology GA 815IV UT WOS:000294520200002 ER PT J AU Crawford, MJ AF Crawford, Michael J. TI Perilous Fight: Americas Intrepid War with Britain on the High Seas, 1812-1815 SO JOURNAL OF MILITARY HISTORY LA English DT Book Review C1 [Crawford, Michael J.] USN, Hist & Heritage Command, Washington, DC USA. RP Crawford, MJ (reprint author), USN, Hist & Heritage Command, Washington, DC USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU SOC MILITARY HISTORY PI LEXINGTON PA C/O VIRGINIA MILITARY INST, GEORGE C MARSHALL LIBRARY, LEXINGTON, VA 24450-1600 USA SN 0899-3718 J9 J MILITARY HIST JI J. Mil. Hist. PD JUL PY 2011 VL 75 IS 3 BP 915 EP 917 PG 3 WC History SC History GA 793VE UT WOS:000292851200024 ER PT J AU Carstairs, SD Kreshak, AA Tanen, DA AF Carstairs, Shaun D. Kreshak, Allyson A. Tanen, David A. TI CROTALINE FAB ANTIVENOM REVERSES PLATELET DYSFUNCTION INDUCED BY C. SCUTULATUS VENOM: AN IN VITRO STUDY SO CLINICAL TOXICOLOGY LA English DT Meeting Abstract C1 [Carstairs, Shaun D.; Tanen, David A.] USN, Med Ctr, San Diego, CA 92152 USA. [Kreshak, Allyson A.] Brown Univ, Providence, RI 02912 USA. NR 0 TC 0 Z9 0 U1 0 U2 3 PU INFORMA HEALTHCARE PI NEW YORK PA 52 VANDERBILT AVE, NEW YORK, NY 10017 USA SN 1556-3650 J9 CLIN TOXICOL JI Clin. Toxicol. PD JUL PY 2011 VL 49 IS 6 MA 2 BP 515 EP 515 PG 1 WC Toxicology SC Toxicology GA 804YS UT WOS:000293692600019 ER PT J AU Bebarta, VS Lairet, J Dixon, P Bourdreau, S Vargas, T Tanen, D AF Bebarta, Vikhyat S. Lairet, Julio Dixon, Patricia Bourdreau, Susan Vargas, Toni Tanen, David TI INTRAOSSEOUS HYDROXOCOBALAMIN VERSUS INTRAMUSCULAR HYDROXYLAMINE IN A VALIDATED SWINE MODEL OF ACUTE CYANIDE TOXICITY AND SHOCK SO CLINICAL TOXICOLOGY LA English DT Meeting Abstract C1 [Dixon, Patricia] Wilford Hall USAF Med Ctr, Clin Res Div, San Antonio, TX 78236 USA. [Tanen, David] USN, Med Ctr San Diego, San Diego, CA 92152 USA. [Bebarta, Vikhyat S.; Lairet, Julio; Bourdreau, Susan; Vargas, Toni] Wilford Hall USAF Med Ctr, Dept Emergency Med, San Antonio, TX 78236 USA. RI Bebarta, Vikhyat/M-1513-2015 NR 0 TC 0 Z9 0 U1 0 U2 3 PU INFORMA HEALTHCARE PI NEW YORK PA 52 VANDERBILT AVE, NEW YORK, NY 10017 USA SN 1556-3650 J9 CLIN TOXICOL JI Clin. Toxicol. PD JUL PY 2011 VL 49 IS 6 MA 7 BP 517 EP 517 PG 1 WC Toxicology SC Toxicology GA 804YS UT WOS:000293692600024 ER PT J AU Dean, RN Anderson, A Reeves, SJ Flowers, GT Hodel, AS AF Dean, Robert Neal Anderson, Abby Reeves, Stanley J. Flowers, George T. Hodel, A. Scottedward TI Electrical Noise in MEMS Capacitive Elements Resulting From Environmental Mechanical Vibrations in Harsh Environments SO IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS LA English DT Article DE Harsh environment; microelectromechanical systems (MEMS); noise AB Many microelectromechanical systems (MEMS) devices possess charged capacitor structures where the suspension system allows relative electrode motion due to internal or external stimuli. When such a device is subjected to external mechanical vibrations present in a harsh operating environment, unwanted movement between the capacitor plates can generate a noise current which is injected into the connected circuitry. This paper analyzes this phenomenon and presents a model for the dynamics of a MEMS device with capacitive plates experiencing relative motion due to external stimuli. A Fourier series expansion of the current is developed to characterize the frequency content of the signal in closed form for a given vibration frequency, and simulation and experimental results are presented. C1 [Dean, Robert Neal; Reeves, Stanley J.; Hodel, A. Scottedward] Auburn Univ, Dept Elect & Comp Engn, Auburn, AL 36849 USA. [Anderson, Abby] USN, Ctr Surface Warfare, Dahlgren, VA 22448 USA. [Flowers, George T.] Auburn Univ, Dept Mech Engn, Auburn, AL 36849 USA. RP Dean, RN (reprint author), Auburn Univ, Dept Elect & Comp Engn, Auburn, AL 36849 USA. EM deanron@auburn.edu; anderson.abby@yahoo.com; reevesj@auburn.edu; flowegt@auburn.edu NR 24 TC 7 Z9 7 U1 1 U2 7 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0278-0046 EI 1557-9948 J9 IEEE T IND ELECTRON JI IEEE Trans. Ind. Electron. PD JUL PY 2011 VL 58 IS 7 BP 2697 EP 2705 DI 10.1109/TIE.2010.2076310 PG 9 WC Automation & Control Systems; Engineering, Electrical & Electronic; Instruments & Instrumentation SC Automation & Control Systems; Engineering; Instruments & Instrumentation GA 806SU UT WOS:000293832600015 ER PT J AU Oriti, G Julian, AL AF Oriti, Giovanna Julian, Alexander L. TI Three-Phase VSI with FPGA-Based Multisampled Space Vector Modulation SO IEEE TRANSACTIONS ON INDUSTRY APPLICATIONS LA English DT Article; Proceedings Paper CT IEEE Energy Conversion Congress and Exposition CY SEP 12-16, 2010 CL Atlanta, GA SP IEEE DE Field-programmable gate arrays (FPGAs); pulsewidth-modulated inverters; sampling methods; space vector modulation ID CONVERTER AB This paper demonstrates improved performance of a three-phase voltage source inverter (VSI) when digital multi-sampled space vector modulation is used. The modulator and the inverter controller are implemented entirely using a field-programmable gate array platform, thus achieving increased bandwidth with respect to a typical digital signal processor or microprocessor-based controller. Increased controller bandwidth results in lower output voltage harmonic distortion in the frequency range above the fundamental and below the switching frequency. Experimental validation is presented together with the analysis carried out using a state space model of a VSI with an output LC filter. C1 [Oriti, Giovanna; Julian, Alexander L.] USN, Postgrad Sch, Dept Elect & Comp Engn, Monterey, CA 93943 USA. RP Oriti, G (reprint author), USN, Postgrad Sch, Dept Elect & Comp Engn, Monterey, CA 93943 USA. EM giovanna.oriti@ieee.org; ajulian@nps.edu NR 18 TC 13 Z9 14 U1 0 U2 4 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0093-9994 J9 IEEE T IND APPL JI IEEE Trans. Ind. Appl. PD JUL-AUG PY 2011 VL 47 IS 4 BP 1813 EP 1820 DI 10.1109/TIA.2011.2154295 PG 8 WC Engineering, Multidisciplinary; Engineering, Electrical & Electronic SC Engineering GA 805EB UT WOS:000293708100032 ER PT J AU Freitas, JA Kim, J Kim, JK Son, CS Jang, S Baik, KH AF Freitas, Jaime A., Jr. Kim, Jihyun Kim, Jong Kyu Son, Chang-Sik Jang, Soohwan Baik, Kwang Hyeon TI Comparison of metal-organic decomposed (MOD) cerium oxide (CeO2) gate deposited on GaN and SiC substrates Preface SO JOURNAL OF CRYSTAL GROWTH LA English DT Editorial Material C1 [Freitas, Jaime A., Jr.] USN, Res Lab, Washington, DC 20375 USA. [Kim, Jihyun] Korea Univ, Seoul, South Korea. [Kim, Jong Kyu] Pohang Univ Sci & Technol, Pohang, South Korea. [Son, Chang-Sik] Silla Univ, Pusan, South Korea. [Jang, Soohwan] Dankook Univ, Seoul, South Korea. [Baik, Kwang Hyeon] Korea Elect Technol Inst, Songnam, South Korea. RP Freitas, JA (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM jaime.freitas@nrl.navy.mil; hyunhyun7@korea.ac.kr; kimjk@postech.ac.kr; csson@silla.ac.kr; jangmountain@dankook.ac.kr; khbaik@keti.re.kr RI Kim, Jihyun/F-6940-2013 NR 0 TC 1 Z9 1 U1 0 U2 12 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0022-0248 J9 J CRYST GROWTH JI J. Cryst. Growth PD JUL 1 PY 2011 VL 326 IS 1 BP 1 EP 1 DI 10.1016/j.jcrysgro.2011.06.020 PG 1 WC Crystallography; Materials Science, Multidisciplinary; Physics, Applied SC Crystallography; Materials Science; Physics GA 802BH UT WOS:000293483800001 ER PT J AU Kim, HY Mastro, MA Hite, J Eddy, CR Kim, J AF Kim, Hong-Yeol Mastro, Michael A. Hite, Jennifer Eddy, Charles R., Jr. Kim, Jihyun TI Photo-enhanced chemical etched GaN LED on silicon substrate SO JOURNAL OF CRYSTAL GROWTH LA English DT Article DE Etching; Gallium nitride; Light-emitting diode ID LIGHT-EMITTING-DIODES; VAPOR-PHASE EPITAXY; QUANTUM EFFICIENCY; GALLIUM NITRIDE; N-GAN; GROWTH; TEMPERATURE; EXTRACTION; CRYSTAL; DENSITY AB In this study, GaN LEDs grown with an intermediate DBR on a Si substrate were chemically etched by 3 M KOH solution under UV light illumination. After 60 min of KOH etching, the hexagonal etch pits and randomized embossments were clearly imaged by SEM and AFM. The etch pits were generated at the threading dislocations, which are common for lattice mismatched growth of GaN on Si. The photoluminescence intensity at 380 nm was enhanced by approximately 21% after PEC etching. The enhanced PL intensity indicated that the generated etch pits and embossments increased the surface area, and effectively increased light scattering effects by randomizing the light rays and increasing the number of scattering events. (C) 2011 Elsevier B.V. All rights reserved. C1 [Kim, Hong-Yeol; Kim, Jihyun] Korea Univ, Dept Chem & Biol Engn, Seoul 136701, South Korea. [Mastro, Michael A.; Hite, Jennifer; Eddy, Charles R., Jr.] USN, Res Lab, Washington, DC 20375 USA. RP Kim, J (reprint author), Korea Univ, Dept Chem & Biol Engn, Seoul 136701, South Korea. EM hyunhyun7@korea.ac.kr RI Kim, Jihyun/F-6940-2013; Hite, Jennifer/L-5637-2015 OI Hite, Jennifer/0000-0002-4090-0826 FU ONR; LG Innotek- Korea University FX The research at NRL was supported by ONR. The research at Korea University was supported by LG Innotek- Korea University Nano-Photonics Program. NR 27 TC 4 Z9 4 U1 0 U2 22 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0022-0248 J9 J CRYST GROWTH JI J. Cryst. Growth PD JUL 1 PY 2011 VL 326 IS 1 BP 58 EP 61 DI 10.1016/j.jcrysgro.2011.01.051 PG 4 WC Crystallography; Materials Science, Multidisciplinary; Physics, Applied SC Crystallography; Materials Science; Physics GA 802BH UT WOS:000293483800013 ER PT J AU Kim, HY Anderson, T Mastro, MA Freitas, JA Jang, S Hite, J Eddy, CR Kim, J AF Kim, Hong-Yeol Anderson, Travis Mastro, Michael A. Freitas, Jaime A., Jr. Jang, Soohwan Hite, Jennifer Eddy, Charles R., Jr. Kim, Jihyun TI Optical and electrical characterization of AlGaN/GaN high electron mobility transistors irradiated with 5 MeV protons SO JOURNAL OF CRYSTAL GROWTH LA English DT Article DE Photoluminescence; Radiation; Semiconducting Gallium Compounds; High Electron Mobility Transistor ID IMPLANTED GAN; RAMAN-SCATTERING; GALLIUM NITRIDE AB An AlGaN/GaN HEMT was irradiated with 5 MeV protons at a dose up to 2 x 10(15)/cm(2). Photoluminescence spectra measured at 5 K indicated that GaN lattice was severely damaged by collisions with high energy protons although distinct near band-edge features were still observable. An I(DS)-V(DS) measurement showed that the current level was decreased by 43% after proton irradiation, and an I(GS)-V(GS) measurement suggested that damage at the metal-contact/AlGaN interface was minimal. Transistor operation was found to be resistant to proton irradiation, which was partially attributed to a self-healing mechanism in proximity to the AlGaN/GaN interface. Published by Elsevier B.V. C1 [Anderson, Travis; Mastro, Michael A.; Freitas, Jaime A., Jr.; Hite, Jennifer; Eddy, Charles R., Jr.] USN, Res Lab, Washington, DC 20375 USA. [Kim, Hong-Yeol; Kim, Jihyun] Korea Univ, Dept Chem & Biol Engn, Seoul, South Korea. [Jang, Soohwan] Dankook Univ, Dept Chem Engn, Yongin 448701, South Korea. RP Mastro, MA (reprint author), USN, Res Lab, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM michael.mastro@nrl.navy.mil; hyunhyun7@korea.ac.kr RI Kim, Jihyun/F-6940-2013; Hite, Jennifer/L-5637-2015 OI Hite, Jennifer/0000-0002-4090-0826 FU Korean government (MEST); Office of Naval Research; Office of Naval Research Global [62909-09-1-4060]; [M2AB02] FX The research at Korea University was supported by Korea Science and Engineering Foundation grant funded by the Korean government (MEST). (Grant code: M2AB02) and BK21 program and was carried out using MC-50 cyclotron at the Korea Institute of Radiological and Medical sciences. The research at NRL was supported by the Office of Naval Research and Office of Naval Research Global (62909-09-1-4060). NR 19 TC 11 Z9 11 U1 2 U2 15 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0022-0248 J9 J CRYST GROWTH JI J. Cryst. Growth PD JUL 1 PY 2011 VL 326 IS 1 BP 62 EP 64 DI 10.1016/j.jcrysgro.2011.01.052 PG 3 WC Crystallography; Materials Science, Multidisciplinary; Physics, Applied SC Crystallography; Materials Science; Physics GA 802BH UT WOS:000293483800014 ER PT J AU Kim, HY Jung, Y Kim, SH Ahn, J Mastro, MA Hite, JK Eddy, CR Kim, J AF Kim, Hong-Yeol Jung, Younghun Kim, Sung Hyun Ahn, Jaehui Mastro, Michael A. Hite, Jennifer K. Eddy, Charles R., Jr. Kim, Jihyun TI Wet etching of non-polar gallium nitride light-emitting diode structure for enhanced light extraction SO JOURNAL OF CRYSTAL GROWTH LA English DT Article DE Gallium compounds; Light-emitting diodes ID 2-DIMENSIONAL PHOTONIC CRYSTAL; GAN AB The surface of a non-polar a-plane GaN light-emitting diode (LED) was intentionally damaged with a KOH wet etch to enhance the extraction of light. This roughening technique has been commonly applied to c-plane polar GaN LEDs to extract photons that would otherwise suffer from total internal refraction. We show that wet etching of the non-polar LED does create a textured surface that increases the light extraction efficiency; however, the mechanism of the etch is quite dissimilar to the etch mechanism observed for c-plane LEDs. In fact, the etch proceeds perpendicular to the a-plane surface along unstable N-face (0 0 0 -1) plane with the Ga-face plane resistant to the etch. The photoluminescence intensity from a-plane non-polar LED after KOH-based wet etching was increased by 83% in our experiments. Therefore, surface roughening by KOH-based wet etch was found to be very effective to extract photons from a-plane non-polar GaN-based LEDs. (C) 2011 Elsevier B.V. All rights reserved. C1 [Kim, Hong-Yeol; Jung, Younghun; Kim, Sung Hyun; Ahn, Jaehui; Kim, Jihyun] Korea Univ, Dept Chem & Biol Engn, Seoul 136701, South Korea. [Mastro, Michael A.; Hite, Jennifer K.; Eddy, Charles R., Jr.] USN, Res Lab, Power Elect Mat Sect, Washington, DC 20375 USA. RP Kim, J (reprint author), Korea Univ, Dept Chem & Biol Engn, Seoul 136701, South Korea. EM hyunhyun7@korea.ac.kr RI Kim, Sung Hyun/F-7292-2013; Kim, Jihyun/F-6940-2013; Hite, Jennifer/L-5637-2015 OI Hite, Jennifer/0000-0002-4090-0826 FU LG Innotek-Korea University; ONR; ONR-Global [N62909-09-1-4060] FX The work at Korea University was supported by LG Innotek-Korea University Nano-Photonics Program. The work at NRL was supported by ONR and ONR-Global(N62909-09-1-4060). NR 11 TC 9 Z9 9 U1 0 U2 20 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0022-0248 J9 J CRYST GROWTH JI J. Cryst. Growth PD JUL 1 PY 2011 VL 326 IS 1 BP 65 EP 68 DI 10.1016/j.jcrysgro.2011.01.053 PG 4 WC Crystallography; Materials Science, Multidisciplinary; Physics, Applied SC Crystallography; Materials Science; Physics GA 802BH UT WOS:000293483800015 ER PT J AU Jung, Y Ahn, J Mastro, MA Hite, JK Feigelson, B Eddy, CR Kim, J AF Jung, Younghun Ahn, Jaehui Mastro, Michael A. Hite, Jennifer K. Feigelson, Boris Eddy, Charles R., Jr. Kim, Jihyun TI Electrical and optical characterization of GaN micro-wires SO JOURNAL OF CRYSTAL GROWTH LA English DT Article DE Etching; Nanostructues; Nitrides; Semiconducting gallium compounds ID GALLIUM NITRIDE; RAMAN-SCATTERING; PLANE GAN; SPECTROSCOPY; PRESSURE; CRYSTALS; SURFACE; POLAR AB A near atmospheric pressure solution growth process was developed to produce an abundant quantity of GaN micro-wires in the c-direction with a length of tens of microns and a diameter of approximately 1-10 mu m. Raman analysis showed that the micro-wires were free of stress which was expected for a free-forming crystal. The lack of stress and extended defects in the GaN micro-wire provided a useful test-bed to directly compare the wet-etch behavior of the polar c-planes and non-polar m-planes in GaN. The etch behavior at the end of the micro-wire (+/- c) was dramatically different, with the (0 0 0 1) plane found to be stable and the (0 0 0 -1) plane observed to rapidly etch into nanoscale hexagonal pyramids. Additionally a dielectrophoretic method was employed to readily align the wires as part of a larger device processing sequence. (C) 2011 Elsevier B.V. All rights reserved. C1 [Jung, Younghun; Ahn, Jaehui; Kim, Jihyun] Korea Univ, Dept Chem & Biol Engn, Seoul 136701, South Korea. [Mastro, Michael A.; Hite, Jennifer K.; Feigelson, Boris; Eddy, Charles R., Jr.] USN, Res Lab, Washington, DC 20375 USA. RP Kim, J (reprint author), Korea Univ, Dept Chem & Biol Engn, Seoul 136701, South Korea. EM hyunhyun7@korea.ac.kr RI Kim, Jihyun/F-6940-2013; Hite, Jennifer/L-5637-2015 OI Hite, Jennifer/0000-0002-4090-0826 FU Ministry of Education, Science and Technology of Korea FX The research at Korea University was supported by the Cabon Dioxide Reduction and Sequestration Center, one of the 21st Century Frontier R&D Program funded by the Ministry of Education, Science and Technology of Korea. NR 23 TC 0 Z9 0 U1 0 U2 12 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0022-0248 J9 J CRYST GROWTH JI J. Cryst. Growth PD JUL 1 PY 2011 VL 326 IS 1 BP 81 EP 84 DI 10.1016/j.jcrysgro.2011.01.057 PG 4 WC Crystallography; Materials Science, Multidisciplinary; Physics, Applied SC Crystallography; Materials Science; Physics GA 802BH UT WOS:000293483800019 ER PT J AU Savelyev, IB Haus, BK Donelan, MA AF Savelyev, Ivan B. Haus, Brian K. Donelan, Mark A. TI Experimental Study on Wind-Wave Momentum Flux in Strongly Forced Conditions SO JOURNAL OF PHYSICAL OCEANOGRAPHY LA English DT Article ID FOLLOWER FIELD-MEASUREMENTS; INPUT SPECTRAL-FUNCTION; SURFACE GRAVITY-WAVES; AIR-FLOW; SEA-SURFACE; SHEAR FLOWS; PRESSURE FLUCTUATIONS; ATMOSPHERIC-PRESSURE; HURRICANE WINDS; WATER-WAVES AB A quantitative description of wind-wave momentum transfer in high wind conditions is necessary for accurate wave models, storm and hurricane forecasting, and models that require atmosphere-ocean coupling such as circulation and mixed layer models. In this work, a static pressure probe mounted on a vertical wave follower to investigate relatively strong winds (U-10 up to 26.9 m s(-1) and U-10/C-p up to 16.6) above waves in laboratory conditions. The main goal of the paper is to quantify the effect of wave shape and airflow sheltering on the momentum transfer and wave growth. Primary results are formulated in terms of wind forcing and wave steepness ak, where a is wave amplitude and k is wave number. It is suggested that, within the studied range (ak up to 0.19), the airflow is best described by the nonseparated sheltering theory. Notably, a small amount of spray and breaking waves was present at the highest wind speeds; however, their effect on the momentum flux was not found to be significant within studied conditions. C1 [Savelyev, Ivan B.] USN, Res Lab, Washington, DC 20375 USA. [Haus, Brian K.; Donelan, Mark A.] Univ Miami, Rosenstiel Sch Marine & Atmospher Sci, Miami, FL 33149 USA. RP Savelyev, IB (reprint author), USN, Res Lab, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM ivansav@gmail.com FU National Science Foundation [OCE 0526318, AGS 0933942]; Office of Naval Research [ONR N000140610288] FX The authors gratefully acknowledge the support of the National Science Foundation (Grants OCE 0526318 and AGS 0933942) and the Office of Naval Research (Grant ONR N000140610288). We thank Mike Rebozo, Tom Snowden, and Hector Garcia for technical assistance during the experiments. NR 46 TC 5 Z9 5 U1 1 U2 6 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 USA SN 0022-3670 J9 J PHYS OCEANOGR JI J. Phys. Oceanogr. PD JUL PY 2011 VL 41 IS 7 BP 1328 EP 1344 DI 10.1175/2011JPO4577.1 PG 17 WC Oceanography SC Oceanography GA 802LP UT WOS:000293513200004 ER PT J AU Jordan, SA AF Jordan, Stephen A. TI Axisymmetric turbulent statistics of long slender circular cylinders SO PHYSICS OF FLUIDS LA English DT Article DE boundary layer turbulence; flow simulation; shapes (structures) ID LARGE-EDDY SIMULATIONS; BOUNDARY-LAYER; THIN CYLINDER; WALL-PRESSURE; AXIAL-FLOW; VELOCITY AB The experimental evidence leads us to believe that long slender circular cylinders have similar axisymmetric turbulent statistics along most of their axial length. The respective boundary layer reaches a maximum thickness (delta) with no further downstream net growth. Despite their small radius (a), these long cylinders still own high radius-based Reynolds numbers (Re(a)) as well as transverse curvatures (delta/a). The influence of these flow conditions (and others) on the turbulent statistics is still chiefly unknown. The present effort begins an investigation that targets axial similarity (or homogeneity) of the long thin cylinder statistics. The database is a collection of previous experimental measurements and observations as well as the present computational results by the large-eddy simulation methodology. Interestingly, this investigation shows that reaching axial homogeneity is reliant essentially on Re(a) with lesser influence by the transverse curvature. But the Re(a) value depends on the turbulent statistic of interest. Likewise, this same result was found for spotting the radial location of the respective statistical peak. Axial homogeneity starts near the cylinder wall then migrates outward radially with increasing Re(a) until full saturation through the turbulent intermediate layer. [doi:10.1063/1.3609272] C1 USN, Undersea Warfare Ctr, Newport, RI 02841 USA. RP Jordan, SA (reprint author), USN, Undersea Warfare Ctr, Newport, RI 02841 USA. EM stephen.jordan@navy.mil FU Office of Naval Research [N0001411AF00002]; Naval Undersea Warfare Center Division Newport FX The author gratefully acknowledges the support of the Office of Naval Research (Dr. Ronald D. Joslin, Program Officer), Contract No. N0001411AF00002, and the In-House Laboratory Independent Research Program (Dr. Anthony A. Ruffa, Program Coordinator) at the Naval Undersea Warfare Center Division Newport. NR 28 TC 8 Z9 8 U1 0 U2 1 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 1070-6631 J9 PHYS FLUIDS JI Phys. Fluids PD JUL PY 2011 VL 23 IS 7 AR 075105 DI 10.1063/1.3609272 PG 11 WC Mechanics; Physics, Fluids & Plasmas SC Mechanics; Physics GA 801ZD UT WOS:000293478200033 ER PT J AU Davis, J Petrov, GM AF Davis, J. Petrov, G. M. TI Neutron production from ultrashort pulse lasers using linear and circular polarization SO PHYSICS OF PLASMAS LA English DT Article ID ION-BEAMS; PROTON-BEAMS; TARGETS; PLASMA; ACCELERATION; IRRADIATION; EMISSION; DRIVEN AB An implicit 2D3V particle-in-cell code is used to study proton and deuteron acceleration from an ultrathin CD foil with thickness between 20 and 200 nm using linear and circular polarization. The proton and deuteron beams drive nuclear fusion reactions from converter foils in a pitcher-catcher set-up. The neutron yield for three representative reactions d-d, d-Li, and p-Li has been calculated analytically using the total neutron production cross section and ion stopping power. For linear polarization, maximum normalized neutron yield of (Y) over bar (d-d) 3.4 x 10(6), (Y) over bar (d-Li) = 3.2 x 10(7), and (Y) over bar (p-Li) 6.8 x 10(6) neutrons/J laser energy has been calculated at the optimum foil thickness of 50 nm. For circular polarization, the optimum foil thickness is 20 nm, for which the corresponding neutron yields are (Y) over bar (d-d) 1.9 x 10(6), (Y) over bar (d-Li) = 2.0 x 10(7), and (Y) over bar (p-Li) = 2.7 x 10(6), respectively. The laser polarization strongly affects the neutron production; for our regime, i.e., intensity I = 1 x 10(21) W/cm(2), pulse duration tau(FWHM) = 30 fs, and laser energy epsilon(laser) = 3.8 J, both the conversion efficiency of laser energy into ion kinetic energy and neutron yield are higher for linear polarization. Only for ultrathin (similar to 20 nm) foils in the radiation pressure acceleration regime, circular and linear polarizations yield comparable results. [doi: 10.1063/1.3615033] C1 [Davis, J.; Petrov, G. M.] USN, Res Lab, Div Plasma Phys, Washington, DC 20375 USA. RP Davis, J (reprint author), USN, Res Lab, Div Plasma Phys, 4555 Overlook Ave SW, Washington, DC 20375 USA. FU ONR; Naval Research Laboratory [6.1] FX This work was supported by ONR and the Naval Research Laboratory under the 6.1 program. We would like to thank the referee of this paper for their insightful comments and suggestions with regard to many numerical and technical issues of the paper. NR 60 TC 2 Z9 2 U1 2 U2 11 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 1070-664X J9 PHYS PLASMAS JI Phys. Plasmas PD JUL PY 2011 VL 18 IS 7 AR 073109 DI 10.1063/1.3615033 PG 6 WC Physics, Fluids & Plasmas SC Physics GA 801XS UT WOS:000293474500044 ER PT J AU Petrov, GM Davis, J AF Petrov, G. M. Davis, J. TI A generalized implicit algorithm for multi-dimensional particle-in-cell simulations in Cartesian geometry SO PHYSICS OF PLASMAS LA English DT Article ID ELECTROMAGNETIC-FIELD ALGORITHM; LASER-TARGET INTERACTIONS; PLASMA SIMULATION; PIC CODE; INSTABILITIES AB An implicit multi-dimensional particle-in-cell (PIC) code is developed to study the interaction of ultrashort pulse lasers with matter. The algorithm is based on current density decomposition and is only marginally more complicated compared to explicit PIC codes, but it completely eliminates grid heating and possesses good energy conserving properties with relaxed time step and grid resolution. This is demonstrated in a test case study, in which high-energy protons are generated from a thin carbon foil at solid density using linear and circular polarizations. The grid heating rate is estimated to be 1-10 eV/ps. [doi: 10.1063/1.3603837] C1 [Petrov, G. M.; Davis, J.] USN, Res Lab, Div Plasma Phys, Washington, DC 20375 USA. RP Petrov, GM (reprint author), USN, Res Lab, Div Plasma Phys, 4555 Overlook Ave SW, Washington, DC 20375 USA. FU Naval Research Laboratory [6.1] FX This work was supported by the Naval Research Laboratory under the 6.1 program. We would like to thank the Referee of this paper for his/her insightful comments and suggestions with regard to many numerical and technical issues of the paper. NR 33 TC 16 Z9 16 U1 1 U2 10 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 1070-664X J9 PHYS PLASMAS JI Phys. Plasmas PD JUL PY 2011 VL 18 IS 7 AR 073102 DI 10.1063/1.3603837 PG 9 WC Physics, Fluids & Plasmas SC Physics GA 801XS UT WOS:000293474500037 ER PT J AU Baggenstoss, PM AF Baggenstoss, Paul M. TI An algorithm for the localization of multiple interfering sperm whales using multi-sensor time difference of arrival SO JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA LA English DT Article AB In this paper an algorithm is described for the localization of individual sperm whales in situations where several near-by animals are simultaneously vocalizing. The algorithm operates on time-difference of arrival (TDOA) measurements observed at sensor pairs and assumes no prior knowledge of the TDOA-whale associations. In other words, it solves the problem of associating TDOAs to whales. The algorithm is able to resolve association disputes where a given TDOA measurement may fit to more than one position estimate and can handle spurious TDOAs. The algorithm also provides estimates of Cramer-Rao lower bound for the position estimates. The algorithm was tested with real data using TDOA estimates obtained by cross-correlating click-trains. The click-trains were generated by a separate algorithm that operated independently on each sensor to produce click-trains corresponding to a given whale and to reject click-trains from reflected propagation paths. [DOI: 10.1121/1.3598454] C1 [Baggenstoss, Paul M.] USN, Undersea Warfare Ctr, Newport, RI 02841 USA. RP Baggenstoss, PM (reprint author), USN, Undersea Warfare Ctr, 1176 Howell St, Newport, RI 02841 USA. EM p.m.baggenstoss@ieee.org FU Joint Industry Programme; US National Marine Fisheries Service FX This research was undertaken partly as a component of the DECAF project (Density Estimation for Cetaceans from passive Acoustic Fixed sensors), funded under the National Oceanographic Partnership Program jointly by the Joint Industry Programme and US National Marine Fisheries Service. I would like to especially thank DECAF project members, Len Thomas and especially Tiago Marques who provided very comprehensive and insightful comments and suggestions. NR 16 TC 15 Z9 16 U1 1 U2 6 PU ACOUSTICAL SOC AMER AMER INST PHYSICS PI MELVILLE PA STE 1 NO 1, 2 HUNTINGTON QUADRANGLE, MELVILLE, NY 11747-4502 USA SN 0001-4966 J9 J ACOUST SOC AM JI J. Acoust. Soc. Am. PD JUL PY 2011 VL 130 IS 1 BP 102 EP 112 DI 10.1121/1.3598454 PG 11 WC Acoustics; Audiology & Speech-Language Pathology SC Acoustics; Audiology & Speech-Language Pathology GA 794SD UT WOS:000292920700021 PM 21786881 ER PT J AU Chin-Bing, SA Jordan, PM Warn-Varnas, A AF Chin-Bing, S. A. Jordan, P. M. Warn-Varnas, A. TI A note on the viscous, 1D shallow water equations: Traveling wave phenomena SO MECHANICS RESEARCH COMMUNICATIONS LA English DT Article DE Viscous shallow water equations; Traveling wave solutions; Bistability; Abel equations; Viscoelasticity ID FLUID; MEDIA; MODEL AB Exact traveling wave solutions (TWS)s of the one-dimensional (1D) shallow water equations are derived and studied in the case of a viscous fluid. These TWSs, which satisfy special cases of Abel's equation, are shown to take the form of kinks, which are not classic Taylor shocks, and to admit bifurcations and steepening. Stability issues are also addressed, asymptotic/limiting case expressions are presented, the possibility of hysteresis is explored, and it is established that bistability only occurs for left-running waves. Last, it is shown that the free surface height is capable of behaving similarly to the strain exhibited by a class of nonlinear viscoelastic media. Published by Elsevier Ltd. C1 [Chin-Bing, S. A.; Jordan, P. M.; Warn-Varnas, A.] USN, Res Lab, Stennis Space Ctr, MS 39529 USA. RP Jordan, PM (reprint author), USN, Res Lab, Stennis Space Ctr, MS 39529 USA. EM pedro.jordan@nrlssc.navy.mil FU ONR/NRL FX This study was initiated by P.M.J. in March 2007 while he was a visitor at OCIAM, Mathematical Institute, Oxford University, Oxford, UK. The authors are indebted to the three anonymous reviewers for their valuable comments and suggestions. All figures appearing in this article were produced using the software package Mathematica (Version 5.2). This work was supported by ONR/NRL funding. NR 23 TC 1 Z9 1 U1 1 U2 1 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0093-6413 J9 MECH RES COMMUN JI Mech. Res. Commun. PD JUL PY 2011 VL 38 IS 5 BP 382 EP 387 DI 10.1016/j.mechrescom.2011.05.003 PG 6 WC Mechanics SC Mechanics GA 805IU UT WOS:000293720900008 ER PT J AU Changela, HG Stroud, RM De Gregorio, BT Nittler, LR Alexander, CMO Cody, GD AF Changela, H. G. Stroud, R. M. De Gregorio, B. T. Nittler, L. R. Alexander, C. M. O'D. Cody, G. D. TI NANOGLOBULE ABUNDANCES IN IOM EXTRACTS: CORRELATION WITH PARENT BODY PROCESSING SO METEORITICS & PLANETARY SCIENCE LA English DT Meeting Abstract CT 74th Annual Meeting of the Meteoritical-Society CY AUG 08-12, 2011 CL London, ENGLAND SP Meteorit Soc, Nat Hist Museum, Imperial Coll, Lunar & Planetary Inst, Natl Aeronaut & Space Adm, European Space Agcy, Barringer Crater Co, CAMECA Instruments, Bruker Nano GmbH, CEPSAR - Open Univ, Univ Leicester, Space Res Ctr, Univ Glasgow, Cambridge Univ Press, Sci (AAAS), WiTec GmbII, Royal Observ Greenwich ID ORGANIC-MATTER; ORIGIN C1 [Changela, H. G.] George Washington Univ, Dept Phys, Washington, DC 20052 USA. [Changela, H. G.; Stroud, R. M.] USN, Res Lab, Washington, DC 20375 USA. [De Gregorio, B. T.] NASA, Lyndon B Johnson Space Ctr, Houston, TX 77058 USA. [Nittler, L. R.; Alexander, C. M. O'D.; Cody, G. D.] Carnegie Inst Washington, Washington, DC 20015 USA. EM changela@anvil.nrl.navy.mil RI De Gregorio, Bradley/B-8465-2008; Stroud, Rhonda/C-5503-2008 OI De Gregorio, Bradley/0000-0001-9096-3545; Stroud, Rhonda/0000-0001-5242-8015 NR 6 TC 0 Z9 0 U1 0 U2 1 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1086-9379 J9 METEORIT PLANET SCI JI Meteorit. Planet. Sci. PD JUL PY 2011 VL 46 SU 1 SI SI BP A39 EP A39 PG 1 WC Geochemistry & Geophysics SC Geochemistry & Geophysics GA 797AN UT WOS:000293094700074 ER PT J AU Peeters, Z Alexander, CMO Changela, H Nittler, LR Price, S Stroud, RM AF Peeters, Z. Alexander, C. M. O'D. Changela, H. Nittler, L. R. Price, S. Stroud, R. M. TI IN SITU SYNCHROTRON X-RAY TRANSMISSION MICROSCOPY OF CR CHONDRITES QUE 99177 AND GRA 95229 SO METEORITICS & PLANETARY SCIENCE LA English DT Meeting Abstract CT 74th Annual Meeting of the Meteoritical-Society CY AUG 08-12, 2011 CL London, ENGLAND SP Meteorit Soc, Nat Hist Museum, Imperial Coll, Lunar & Planetary Inst, Natl Aeronaut & Space Adm, European Space Agcy, Barringer Crater Co, CAMECA Instruments, Bruker Nano GmbH, CEPSAR - Open Univ, Univ Leicester, Space Res Ctr, Univ Glasgow, Cambridge Univ Press, Sci (AAAS), WiTec GmbII, Royal Observ Greenwich C1 [Peeters, Z.; Alexander, C. M. O'D.; Nittler, L. R.; Price, S.] Carnegie Inst Washington, Washington, DC 20015 USA. [Changela, H.; Stroud, R. M.] USN, Res Lab, Code 6s366, Washington, DC 20375 USA. EM zpeeters@dtm.ciw.edu RI Stroud, Rhonda/C-5503-2008 OI Stroud, Rhonda/0000-0001-5242-8015 NR 4 TC 13 Z9 13 U1 0 U2 0 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1086-9379 J9 METEORIT PLANET SCI JI Meteorit. Planet. Sci. PD JUL PY 2011 VL 46 SU 1 SI SI BP A185 EP A185 PG 1 WC Geochemistry & Geophysics SC Geochemistry & Geophysics GA 797AN UT WOS:000293094700366 ER PT J AU Sandford, SA Nuevo, M Milam, SN Cody, GD Kilcoyne, ALD De Gregorio, BT Stroud, RM AF Sandford, S. A. Nuevo, M. Milam, S. N. Cody, G. D. Kilcoyne, A. L. D. De Gregorio, B. T. Stroud, R. M. TI XANES ANALYSIS OF ORGANIC RESIDUES FROM THE IRRADIATION OF ASTROPHYSICAL ICE ANALOGS AND COMPARISON WITH Stardust SAMPLES SO METEORITICS & PLANETARY SCIENCE LA English DT Meeting Abstract CT 74th Annual Meeting of the Meteoritical-Society CY AUG 08-12, 2011 CL London, ENGLAND SP Meteorit Soc, Nat Hist Museum, Imperial Coll, Lunar & Planetary Inst, Natl Aeronaut & Space Adm, European Space Agcy, Barringer Crater Co, CAMECA Instruments, Bruker Nano GmbH, CEPSAR - Open Univ, Univ Leicester, Space Res Ctr, Univ Glasgow, Cambridge Univ Press, Sci (AAAS), WiTec GmbII, Royal Observ Greenwich ID AMINO-ACIDS; COMET 81P/WILD-2 C1 [Sandford, S. A.; Nuevo, M.] NASA, Ames Res Ctr, Moffett Field, CA 94035 USA. [Milam, S. N.] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA. [Cody, G. D.] Carnegie Inst Washington, Washington, DC 20005 USA. [Kilcoyne, A. L. D.] Adv Light Source, Berkeley, CA USA. [De Gregorio, B. T.] NASA, Lyndon B Johnson Space Ctr, Houston, TX 77058 USA. [Stroud, R. M.] USN, Res Lab, Washington, DC 20375 USA. EM Scott.A.Sandford@nasa.gov RI Milam, Stefanie/D-1092-2012; De Gregorio, Bradley/B-8465-2008; Kilcoyne, David/I-1465-2013; Stroud, Rhonda/C-5503-2008 OI Milam, Stefanie/0000-0001-7694-4129; De Gregorio, Bradley/0000-0001-9096-3545; Stroud, Rhonda/0000-0001-5242-8015 NR 9 TC 0 Z9 0 U1 0 U2 1 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1086-9379 J9 METEORIT PLANET SCI JI Meteorit. Planet. Sci. PD JUL PY 2011 VL 46 SU 1 SI SI BP A204 EP A204 PG 1 WC Geochemistry & Geophysics SC Geochemistry & Geophysics GA 797AN UT WOS:000293094700404 ER PT J AU Starkey, NA Franchi, IA Bridges, JC Changela, HG Hicks, LJ AF Starkey, N. A. Franchi, I. A. Bridges, J. C. Changela, H. G. Hicks, L. J. TI OXYGEN ISOTOPE ANALYSIS OF A CHONDRULE-LIKE WILD 2 TERMINAL PARTICLE USING NANOSIMS SO METEORITICS & PLANETARY SCIENCE LA English DT Meeting Abstract CT 74th Annual Meeting of the Meteoritical-Society CY AUG 08-12, 2011 CL London, ENGLAND SP Meteorit Soc, Nat Hist Museum, Imperial Coll, Lunar & Planetary Inst, Natl Aeronaut & Space Adm, European Space Agcy, Barringer Crater Co, CAMECA Instruments, Bruker Nano GmbH, CEPSAR - Open Univ, Univ Leicester, Space Res Ctr, Univ Glasgow, Cambridge Univ Press, Sci (AAAS), WiTec GmbII, Royal Observ Greenwich C1 [Starkey, N. A.; Franchi, I. A.] Open Univ, PSSRI, Milton Keynes MK7 6AA, Bucks, England. [Bridges, J. C.; Changela, H. G.; Hicks, L. J.] Univ Leicester, SRC, Leicester LE1 7RH, Leics, England. [Changela, H. G.] NRL, Washington, DC 20375 USA. EM n.starkey@open.ac.uk NR 5 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1086-9379 J9 METEORIT PLANET SCI JI Meteorit. Planet. Sci. PD JUL PY 2011 VL 46 SU 1 SI SI BP A221 EP A221 PG 1 WC Geochemistry & Geophysics SC Geochemistry & Geophysics GA 797AN UT WOS:000293094700439 ER PT J AU Foley, AW Keith, WL Cipolla, KM AF Foley, A. W. Keith, W. L. Cipolla, K. M. TI Comparison of theoretical and experimental wall pressure wavenumber-frequency spectra for axisymnnetric and flat-plate turbulent boundary layers SO OCEAN ENGINEERING LA English DT Article DE Flow noise; Turbulence; Turbulent boundary layer; Wall pressure; Wavenumber-frequency spectra ID FLUCTUATIONS; FEATURES; BENEATH; MODEL AB The measurement and analysis of turbulent boundary layer wall pressure fluctuations using a wavenumber filter of sensors provide quantitative knowledge of turbulence physics. In addition, the sources of flow-induced noise and vibration for towed SONAR arrays can be determined. An axisymmetric turbulent boundary layer can have significantly different features than those of a comparable flat-plate boundary layer. Here, a detailed comparison of the distribution of wall pressure energy in both wavenumber and frequency between flat-plate and thick axisymmetric boundary layers is presented. The background theory of wavenumber-frequency spectra and state-of-the-art models for flat-plate boundary layers are discussed. The widely used model of Chase (1987), valid for flat-plate boundary layers over a wide range of Reynolds numbers, is used and combined with a sensor response function to allow the effects of spatial averaging to be considered. It is demonstrated that when measured boundary layer parameters for the axisymmetric case are used in the Chase flat-plate model, the results accurately predict the axisymmetric boundary layer wall pressure measurements. Published by Elsevier Ltd. C1 [Foley, A. W.; Keith, W. L.; Cipolla, K. M.] Naval Sea Syst Command Newport, Naval Undersea Warfare Ctr, Devices Sensors & Mat R&D Branch, Sensors & Sonar Syst Dept, Newport, RI 02841 USA. RP Keith, WL (reprint author), Naval Sea Syst Command Newport, Naval Undersea Warfare Ctr, Devices Sensors & Mat R&D Branch, Sensors & Sonar Syst Dept, 1176 Howell St, Newport, RI 02841 USA. EM alia.foley@navy.mil; william.keith@navy.mil; kimberly.cipolla@navy.mil FU Naval Undersea Warfare Center Division Newport Virtual In-House Laboratory Independent Research Program FX This effort was funded under the Naval Undersea Warfare Center Division Newport Virtual In-House Laboratory Independent Research Program, Program Manager Dr. Anthony Ruffa. NR 10 TC 1 Z9 1 U1 2 U2 7 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0029-8018 J9 OCEAN ENG JI Ocean Eng. PD JUL PY 2011 VL 38 IS 10 BP 1123 EP 1129 DI 10.1016/j.oceaneng.2011.05.001 PG 7 WC Engineering, Marine; Engineering, Civil; Engineering, Ocean; Oceanography SC Engineering; Oceanography GA 804TR UT WOS:000293677400008 ER PT J AU Hite, JK Twigg, ME Mastro, MA Eddy, CR Kub, FJ AF Hite, Jennifer K. Twigg, Mark E. Mastro, Michael A. Eddy, Charles R., Jr. Kub, Francis J. TI Initiating polarity inversion in GaN growth using an AlN interlayer SO PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE LA English DT Article DE III-V; GaN; inversion; polarity ID SUBSTRATE; GAN(0001); FILMS; MG AB In this work, we show that the polarity of GaN grown on N-polar material can be controlled through a combination of surface conditioning and introduction of a non-Mg inversion layer (IL). The IL we use is a thin, low-temperature AlN layer deposited by metal organic chemical vapor deposition (MOCVD). The subsequent inverted films are Ga-polar that do not contain inversion domain boundaries and with crystal quality similar to MOCVD films grown on sapphire. The polarity inversion technique is enhanced by the addition of an etching step prior to AlN deposition. (C) 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim C1 [Hite, Jennifer K.; Twigg, Mark E.; Mastro, Michael A.; Eddy, Charles R., Jr.; Kub, Francis J.] USN, Res Lab, Washington, DC 20375 USA. RP Hite, JK (reprint author), USN, Res Lab, Power Elect Sect Code 6882, Washington, DC 20375 USA. EM jennifer.hite@nrl.navy.mil RI Hite, Jennifer/L-5637-2015 OI Hite, Jennifer/0000-0002-4090-0826 FU Office of Naval Research; ASEE FX This work was supported under the Office of Naval Research. JKH would also like to thank the ASEE Postdoctoral Fellowship Program for support. NR 14 TC 14 Z9 14 U1 1 U2 38 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1862-6300 J9 PHYS STATUS SOLIDI A JI Phys. Status Solidi A-Appl. Mat. PD JUL PY 2011 VL 208 IS 7 BP 1504 EP 1506 DI 10.1002/pssa.201001123 PG 3 WC Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter SC Materials Science; Physics GA 806JL UT WOS:000293803600005 ER PT J AU Meyer, DJ Katzer, DS Deen, DA Storm, DF Binari, SC Gougousi, T AF Meyer, D. J. Katzer, D. S. Deen, D. A. Storm, D. F. Binari, S. C. Gougousi, T. TI HfO2-insulated gate N-polar GaN HEMTs with high breakdown voltage SO PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE LA English DT Article DE ALD; iHEMT; MIS; pulsed I-V ID ALGAN/GAN HEMTS AB In this paper, we present the first demonstration of a HfO2-insulated gate N-polar GaN inverted high-electron-mobility transistor (iHEMT). HfO2-insulated gate devices showed an order of magnitude improvement in reverse bias gate leakage current as compared to reference Schottky devices. With the reduced gate leakage current, the insulated gate iHEMTs were able to simultaneously demonstrate breakdown voltages in excess of 130 V and maximum current density of 0.87 A/mm. Pulsed I-V gate-lag measurements were performed to investigate the dram current transient behavior of these devices. (C) 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim C1 [Meyer, D. J.; Katzer, D. S.; Deen, D. A.; Storm, D. F.; Binari, S. C.] USN, Res Lab, Div Elect Sci & Technol, Washington, DC 20375 USA. [Gougousi, T.] Univ Maryland Baltimore Cty, Dept Phys, Baltimore, MD 21250 USA. RP Meyer, DJ (reprint author), USN, Res Lab, Div Elect Sci & Technol, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM david.meyer@nrl.navy.mil RI Katzer, D. Scott/N-7841-2013; Gougousi, Theodosia/C-8156-2014 FU Office of Naval Research; NSF [DMR 0846445] FX The authors would like to thank Neil Green for his assistance with device fabrication. This work was supported by the Office of Naval Research. The HfO2 ALD work at UMBC was supported in part by NSF (DMR 0846445). NR 17 TC 13 Z9 14 U1 0 U2 16 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1862-6300 J9 PHYS STATUS SOLIDI A JI Phys. Status Solidi A-Appl. Mat. PD JUL PY 2011 VL 208 IS 7 BP 1630 EP 1633 DI 10.1002/pssa.201001080 PG 4 WC Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter SC Materials Science; Physics GA 806JL UT WOS:000293803600042 ER PT J AU Mondry, TE Mondry, JM Soballe, PW AF Mondry, Tammy E. Mondry, Joseph M. Soballe, Peter W. TI Cancer Treatment-Related Lymphedema in Geriatrics SO TOPICS IN GERIATRIC REHABILITATION LA English DT Article DE cancer; lymphedema; prevention; self-management; treatment ID BREAST-CONSERVING TREATMENT; NODE DISSECTION; SECONDARY LYMPHEDEMA; RISK-FACTORS; ADJUVANT RADIOTHERAPY; RADICAL HYSTERECTOMY; CUTANEOUS MELANOMA; CERVICAL-CANCER; BIOPSY; TRIAL AB Cancer treatment-related lymphedema is a chronic, incurable disorder that can significantly affect quality of life. It is caused by a mechanical alteration of the lymphatic system during surgery and/or radiation therapy for the treatment of cancer. Lymphedema can have several adverse effects to include increased risk of cellulitis, decreased productivity, disability, psychosocial impacts, and poor body image issues. The purpose of this article is to discuss current clinical practices for risk reduction, identification, treatment, and maintenance of this condition. C1 [Mondry, Tammy E.; Mondry, Joseph M.] New Horizons Phys Therapy, San Diego, CA 92130 USA. [Soballe, Peter W.] USN, Dept Surg, San Diego Med Ctr, San Diego, CA 92152 USA. RP Mondry, TE (reprint author), New Horizons Phys Therapy, 11622 El Camino Real,Ste 100, San Diego, CA 92130 USA. EM newhorizonspt@cox.net NR 55 TC 0 Z9 0 U1 0 U2 2 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0882-7524 J9 TOP GERIATR REHABIL JI Top. Geriatr. Rehabil. PD JUL-SEP PY 2011 VL 27 IS 3 BP 215 EP 221 DI 10.1097/TGR.0b013e31821990cf PG 7 WC Gerontology; Rehabilitation SC Geriatrics & Gerontology; Rehabilitation GA 802IQ UT WOS:000293503600008 ER PT J AU Moon, S Menon, D Barndt, G AF Moon, Suresh Menon, Dinesh Barndt, Gene TI Fatigue Life Reliability Based on Measured Usage, Flight Loads, and Fatigue Strength Variations SO JOURNAL OF THE AMERICAN HELICOPTER SOCIETY LA English DT Article AB The U. S. Navy has developed a usage monitoring system based on the regime recognition concept for tracking rotary wing aircraft fatigue components and structures. Thus far, 50 AH-1W aircraft have been equipped with the Structural Data Recording Set (SDRS), acquiring 3400 valid flight hours of usage. The usage variations in each regime are modeled using a Weibull distribution. Similarly, the load variations in each regime are also modeled using a Weibull distribution. The strength variation was obtained from the aluminum alloy-264 full-scale component fatigue test data. This variation is modeled using a Weibull distribution. The usage, load, and strength variations are then combined to compute fatigue life and the associated multivariate probability of failure and reliability. The component fatigue lives versus the reliability curve will help the U. S. Navy plan component retirements with specified risks. In addition, the individual contribution from usage, loads, strength, and cycle counting to six nines reliability are calculated. Finally, the impact of usage monitoring on reliability is assessed and the bivariate standard deviation required to achieve six nines reliability is evaluated. C1 [Moon, Suresh] L3 Commun, Air Vehicle Engn, Lexington Pk, MD USA. [Menon, Dinesh] AeroStructures Inc, Crystal City, VA USA. [Barndt, Gene] USN, Air Syst Command, Struct Div, Ret Rotary Wing Branch, Patuxent River, MD USA. RP Moon, S (reprint author), L3 Commun, Air Vehicle Engn, Lexington Pk, MD USA. EM suresh.moon@L-3com.com NR 12 TC 0 Z9 0 U1 0 U2 4 PU AMER HELICOPTER SOC INC PI ALEXANDRIA PA 217 N WASHINGTON ST, ALEXANDRIA, VA 22314 USA SN 0002-8711 J9 J AM HELICOPTER SOC JI J. Am. Helicopter Soc. PD JUL PY 2011 VL 56 IS 3 AR 032006 DI 10.4050/JAHS.56.032006 PG 18 WC Engineering, Aerospace SC Engineering GA 800TU UT WOS:000293391000007 ER PT J AU Ghersi, BM Sovero, MM Icochea, E Gonzalez, RI Blazes, DL Gonzalez, AE Montgomery, JM AF Ghersi, Bruno M. Sovero, Merly M. Icochea, Eliana Gonzalez, Rosa I. Blazes, David L. Gonzalez, Armando E. Montgomery, Joel M. TI Isolation of Low-pathogenic H7N3 Avian Influenza from Wild Birds in Peru SO JOURNAL OF WILDLIFE DISEASES LA English DT Article ID SOUTH-AMERICA; OUTBREAK; NORTH; LINEAGES; GENES AB Wild birds serve as natural reservoirs and sometimes harbor low-pathogenic avian influenza viruses. However, mutation of the virus can result in highly pathogenic strains, often more common among H5 and H7 genotypes. We report the isolation of a low-pathogenic H7N3 avian influenza in a Peruvian wetland. C1 [Ghersi, Bruno M.; Icochea, Eliana; Gonzalez, Rosa I.; Gonzalez, Armando E.] Univ Nacl Mayor San Marcos, Sch Vet Med, Lima 14, Peru. [Ghersi, Bruno M.; Sovero, Merly M.; Montgomery, Joel M.] USN, Med Res Unit 6, Washington, DC 20521 USA. [Blazes, David L.] Armed Forces Hlth Surveillance Ctr, Silver Spring, MD 20910 USA. RP Ghersi, BM (reprint author), Univ Nacl Mayor San Marcos, Sch Vet Med, Av Circunvalac Cdra 28 S-N, Lima 14, Peru. EM bruno.ghersi@med.navy.mil FU US Department of Defense, Armed Forces Health Surveillance Center, Global Emerging Infections Surveillance and Response System FX We thank Rodrigo Iglesias for help in the field; Gloria Chauca for help with influenza strain identification; and Ernesto Ortiz, Gabriela Salmon, and Erik Reaves for helpful reviews of the manuscript. This work was supported by the US Department of Defense, Armed Forces Health Surveillance Center, Global Emerging Infections Surveillance and Response System. The views expressed in this article are those of the authors and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, or the US Government. NR 12 TC 6 Z9 6 U1 1 U2 2 PU WILDLIFE DISEASE ASSOC, INC PI LAWRENCE PA 810 EAST 10TH ST, LAWRENCE, KS 66044-8897 USA SN 0090-3558 J9 J WILDLIFE DIS JI J. Wildl. Dis. PD JUL PY 2011 VL 47 IS 3 BP 792 EP 795 PG 4 WC Veterinary Sciences SC Veterinary Sciences GA 793CR UT WOS:000292798500044 PM 21719856 ER PT J AU Jennings, TL Becker-Catania, SG Triulzi, RC Tao, GL Scott, B Sapsford, KE Spindel, S Oh, E Jain, V Delehanty, JB Prasuhn, DE Boeneman, K Algar, WR Medintz, IL AF Jennings, Travis L. Becker-Catania, Sara G. Triulzi, Robert C. Tao, Guoliang Scott, Bradley Sapsford, Kim E. Spindel, Samantha Oh, Eunkeu Jain, Vaibhav Delehanty, James. B. Prasuhn, Duane E. Boeneman, Kelly Algar, W. Russ Medintz, Igor L. TI Reactive Semiconductor Nanocrystals for Chemoselective Biolabeling and Multiplexed Analysis SO ACS NANO LA English DT Article DE nanocrystal; semiconductor; quantum dot; bioconjugation; chemoselective; probe; cellular imaging; multiplexing ID QUANTUM DOTS; BIOORTHOGONAL CHEMISTRY; DELIVERY; NANOPARTICLES; NANOTECHNOLOGY; BIOMOLECULES; STRATEGIES; LIGATION; PROTEINS; SURFACES AB Effective biological application of nanocrystalline semiconductor quantum dots continues to be hampered by the lack of easily implemented and widely applicable labeling chemistries. Here, we introduce two new orthogonal nanocrystal bioconjugation chemistries that overcome many of the labeling issues associated with currently utilized approaches. These chemistries specifically target either (1) the ubiquitous amines found on proteins or (2) thiols present In either antibody hinge regions or recombinantly introduced into other proteins to facilitate site-specific labeling. The amine chemistry incorporates aniline-catalyzed hydrazone bond formation, while the sulfhydryl chemistry utilizes nanouystals displaying surface activated maleimide groups. Both reactive chemistries are rapidly implemented, yielding purified nanocrystal protein bioconjugates in as little as 3 h. Following initial characterization of the nanocrystal materials, the wide applicability and strong multiplexing potential of these chemistries are demonstrated in an array of applications including immunoassays, immunolabeling in both cellular and tissue samples, in vivo cellular uptake, and flow cytometry. Side-by-side comparison of the immunolabeled cells suggested a functional equivalence between results generated with the amine and thiol-labeled antibody nanocrystal bioconjugates In that format. Three-color labeling was achieved in the cellular uptake format, with no significant toxicity observed while simultaneous five-color labeling of different epitopes was demonstrated for the immunolabeled tissue sample. Novel labeling applications are also facilitated by these chemistries, as highlighted by the ability to directly label cellular membranes in adherent cell cultures with the thiol-reactive chemistry. C1 [Jennings, Travis L.; Becker-Catania, Sara G.; Triulzi, Robert C.; Tao, Guoliang; Scott, Bradley] EBioscience Inc, San Diego, CA 92121 USA. [Sapsford, Kim E.; Spindel, Samantha] US FDA, Div Biol, Sci & Engn Labs, Silver Spring, MD 20993 USA. [Delehanty, James. B.; Prasuhn, Duane E.; Boeneman, Kelly; Algar, W. Russ; Medintz, Igor L.] USN, Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. [Oh, Eunkeu; Jain, Vaibhav] USN, Res Lab, Div Opt Sci, Washington, DC 20375 USA. [Algar, W. Russ] George Mason Univ, Coll Sci, Fairfax, VA 22030 USA. RP Jennings, TL (reprint author), EBioscience Inc, 10255 Sci Ctr Dr, San Diego, CA 92121 USA. EM travis.jennings@ebioscience.com; igor.medintz@nrl.navy.mil RI Gemmill, Kelly/G-2167-2012 FU CB Directorate/Physical S&T Division (DTRA), DARPA, ONR, NRL; NRL-NSI; Critical Path Initiative FDA; Natural Sciences and Engineering Research Council of Canada (NSERC) FX The authors acknowledge the CB Directorate/Physical S&T Division (DTRA), DARPA, ONR, NRL, and the NRL-NSI for financial support. K.B. and D.P. acknowledge ASEE fellowships through NRL. KS. and S.S. acknowledge the Critical Path Initiative FDA for financial support. T.L.J. is grateful to Drs. M. Fung and C. Funatake for helpful discussions and interpretations in flow cytometry. W.R.A. is grateful to the Natural Sciences and Engineering Research Council of Canada (NSERC) for support through a postdoctoral fellowship. NR 54 TC 47 Z9 47 U1 4 U2 51 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1936-0851 EI 1936-086X J9 ACS NANO JI ACS Nano PD JUL PY 2011 VL 5 IS 7 BP 5579 EP 5593 DI 10.1021/nn201050g PG 15 WC Chemistry, Multidisciplinary; Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Chemistry; Science & Technology - Other Topics; Materials Science GA 796ES UT WOS:000293035200036 PM 21692444 ER PT J AU Rakowski, CE Laming, JM Hwang, U Eriksen, KA Ghavamian, P Hughes, JP AF Rakowski, Cara E. Laming, J. Martin Hwang, Una Eriksen, Kristoffer A. Ghavamian, Parviz Hughes, John P. TI THE EFFECT OF A COSMIC RAY PRECURSOR IN SN 1006? SO ASTROPHYSICAL JOURNAL LETTERS LA English DT Article DE acceleration of particles; cosmic rays; ISM: supernova remnants; shock waves; supernovae: individual (SN 1006) ID TYCHOS SUPERNOVA-REMNANT; DIFFUSIVE SHOCK ACCELERATION; RAYLEIGH-TAYLOR INSTABILITY; CONFINED DETONATION MODEL; PARTICLE-ACCELERATION; IA-SUPERNOVAE; BLAST WAVE; MAGNETIC-FIELD; EVOLUTION; SN-1006 AB Like many young supernova remnants, SN 1006 exhibits what appear to be clumps of ejecta close to or protruding beyond the main blast wave. In this Letter, we examine three such protrusions along the east rim. They are semi-aligned with ejecta fingers behind the shock-front and exhibit emission lines from O VII and O VIII. We first interpret them in the context of an upstream medium modified by the saturated non-resonant Bell instability which enhances the growth of Rayleigh-Taylor instabilities when advected post-shock. We discuss their apparent periodicity if the spacing is determined by properties of the remnant or by a preferred size scale in the cosmic ray precursor. We also briefly discuss the alternative that these structures have an origin in the ejecta structure of the explosion itself. In this case, the young evolutionary age of SN 1006 would imply density structure within the outermost layers of the explosion with potentially important implications for deflagration and detonation in thermonuclear supernova explosion models. C1 [Rakowski, Cara E.; Laming, J. Martin] USN, Div Space Sci, Res Lab, Washington, DC 20375 USA. [Hwang, Una] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA. [Eriksen, Kristoffer A.; Hughes, John P.] Rutgers State Univ, Piscataway, NJ 08854 USA. [Ghavamian, Parviz] Space Telescope Sci Inst, Baltimore, MD 21218 USA. RP Rakowski, CE (reprint author), USN, Div Space Sci, Res Lab, Code 7671, Washington, DC 20375 USA. FU NASA [NNH10A009I]; Office of Naval Research; Chandra [GO9-0078X]; HST at STScI [GO-11184.07A] FX C.E.R and J.M.L acknowledge support from NASA contract NNH10A009I and basic research funds from the Office of Naval Research. K. A. E and J.P.H acknowledge support from Chandra grant number GO9-0078X to Rutgers University. P. G. acknowledges HST grant GO-11184.07A at STScI. NR 35 TC 13 Z9 13 U1 0 U2 5 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 2041-8205 J9 ASTROPHYS J LETT JI Astrophys. J. Lett. PD JUL 1 PY 2011 VL 735 IS 1 AR L21 DI 10.1088/2041-8205/735/1/L21 PG 5 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 797OT UT WOS:000293137900021 ER PT J AU Stehman, CR Buckley, RG Dos Santos, FL Riffenburgh, RH Swenson, A Mulligan, S Mjos, N Brewer, M AF Stehman, Christine R. Buckley, Robert G. Dos Santos, Frank L. Riffenburgh, Robert H. Swenson, Aaron Mulligan, Sheila Mjos, Nathan Brewer, Matt TI BEDSIDE ESTIMATION OF PATIENT HEIGHT FOR CALCULATING IDEAL BODY WEIGHT IN THE EMERGENCY DEPARTMENT SO JOURNAL OF EMERGENCY MEDICINE LA English DT Article DE ideal body weight; drug dosing; ventilator volume settings; medical error ID ACCURACY; DISPOSITION; OBESITY AB Background: Ideal body weight (IBW), which can be calculated using the variables of true height and sex, is important for drug dosing and ventilator settings. True height often cannot be measured in the emergency department (ED). Objectives: Determine the most accurate method to estimate IBW using true height-based IBW that uses true height estimated by providers or patients compared to true height estimated by a regression formula using measured tibial length, and compare all to the conventional 70 kg male/60 kg female standard IBW. Methods: Prospective, observational, double-blind, convenience sampling of stable adult patients in a tertiary care ED from September 2004 to April 2006. Derivation set (215 patients) had blinded provider and patient true height estimates and tibial length measurements compared to gold-standard standing true height. A validation set (102 patients) then compared the accuracy of IBW using true height calculated from the regression formula vs. IBW using gold-standard true height. Regression formula for men tibial length-IBW (kg) = 25.83 + 1.11 x tibial length; for women tibial length-IBVV = 7.90 + 1.20 x tibial length; R(2) = 0.89, p < 0.001. Inter-rater correlation of tibial length was 0.94. Results: Derivation set: percent within 5 kg of true height-based IBW for men/women = Patient: 91.1 %:/85.7%; Physician: 66.1 %/45.1%; Nurse: 65.7%/ 47.3%; tibial length: 66.1%/63.7%; and 70 kg male/60 kg female standard 46%/75%. Validation set: tibial length-IBW estimates were within 5 kg of true height-ideal body weight in only 56.2% of men and 42.2% of women. Conclusions: Patient-reported height is the best bedside method to estimate true height to calculate ideal body weight. Physician and nurse estimates of true height are substantially less accurate, as is true height obtained from a regression formula that uses measured tibial length. All methods were more accurate than using the conventional 70 kg male/60 kg female IBW standard. (C) 2011 Published by Elsevier Inc. C1 [Riffenburgh, Robert H.] USN, Med Ctr, Dept Clin Invest, San Diego, CA 92134 USA. [Dos Santos, Frank L.] US Naval Hosp, Naples, Italy. [Riffenburgh, Robert H.] San Diego State Univ, Dept Math & Stat, San Diego, CA 92182 USA. [Swenson, Aaron] Dartmouth Coll, Sch Med, Hanover, NH USA. [Mulligan, Sheila] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA. [Mjos, Nathan; Brewer, Matt] Western Univ Hlth Sci, Pomona, CA USA. RP Buckley, RG (reprint author), USN, San Diego Med Ctr, Emergency Dept, 34800 Bob Wilson Dr, San Diego, CA 92134 USA. NR 13 TC 4 Z9 5 U1 0 U2 3 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 0736-4679 J9 J EMERG MED JI J. Emerg. Med. PD JUL PY 2011 VL 41 IS 1 BP 97 EP 101 DI 10.1016/j.jemermed.2009.12.016 PG 5 WC Emergency Medicine SC Emergency Medicine GA 798KB UT WOS:000293203500024 PM 20189741 ER PT J AU Miller, SF Arul, SG Kruger, GH Pan, TY Shih, AJ AF Miller, Scott F. Arul, Senthil G. Kruger, Grant H. Pan, Tsung-Yu Shih, Albert J. TI Effect of Localized Metal Matrix Composite Formation on Spot Friction Welding Joint Strength SO JOURNAL OF ENGINEERING MATERIALS AND TECHNOLOGY-TRANSACTIONS OF THE ASME LA English DT Article DE friction stir welding; metal matrix composite; joint strength ID ALUMINUM; FLOW; REINFORCEMENT; BEHAVIOR; CREEP AB In this study, metal particles were added during the spot friction welding (SFW) process, a solid state sheet metal joining process, to create a localized metal matrix composite (MMC) for the improvement of lap shear strength in AISI 6111-T4 aluminum alloy sheets. The Ancorsteel (R) 1000 particles were compressed between the upper and lower sheets and distributed concentrically around the tool axis perpendicular to the plate surface, which formed a localized MMC and were effective as the reinforcement particles in aluminum 6111-T4 alloy sheets. Results revealed that the MMC reinforcement improved the lap shear strength of SFW joints by about 25%. An aluminum-ferrous solid solution was formed around the steel particles along the aluminum matrix interface. The load-deflection curve shows that the steel particle MMC increased both the strength and ductility of SFW joint. This is attributed to two phenomena observed on the failed lap shear tensile specimens with SFW MMC. One is the longer and more torturous crack path, and the other is the secondary crack on steel particle MMC reinforced SFW joints. [DOI: 10.1115/1.4004389] C1 [Miller, Scott F.] Univ Hawaii Manoa, Honolulu, HI 96822 USA. [Arul, Senthil G.] USN, Sea Syst Command, Dept Navy, Washington, DC 20376 USA. [Kruger, Grant H.; Shih, Albert J.] Univ Michigan, Ann Arbor, MI 48109 USA. [Pan, Tsung-Yu] Oak Ridge Natl Lab, Oak Ridge, TN 37831 USA. RP Miller, SF (reprint author), Univ Hawaii Manoa, Honolulu, HI 96822 USA. FU Ford Motor Company; NSF [0700617] FX We acknowledge the support from Ford Motor Company and NSF CMMI Grant No. 0700617. NR 23 TC 0 Z9 0 U1 0 U2 9 PU ASME-AMER SOC MECHANICAL ENG PI NEW YORK PA THREE PARK AVE, NEW YORK, NY 10016-5990 USA SN 0094-4289 J9 J ENG MATER-T ASME JI J. Eng. Mater. Technol.-Trans. ASME PD JUL PY 2011 VL 133 IS 3 AR 031009 DI 10.1115/1.4004389 PG 8 WC Engineering, Mechanical; Materials Science, Multidisciplinary SC Engineering; Materials Science GA 794TD UT WOS:000292923300018 ER PT J AU Rolison, DR Nazar, LF AF Rolison, Debra R. Nazar, Linda F. TI Electrochemical energy storage to power the 21st century SO MRS BULLETIN LA English DT Article ID VANADIUM-OXIDE AEROGELS; LITHIUM-ION; TEMPLATE SYNTHESIS; CATION VACANCIES; INTERCALATION; BATTERIES; ELECTRODE; PERFORMANCE; NANOWIRES; MNO2 AB Climate change, diminishing reserves of fossil fuels, energy security, and consumer demand all depend on alternatives to our current course of energy usage and consumption. A broad consensus concurs that implementing energy efficiency and renewable energy technologies are necessities now rather than luxuries to be deferred to some distant future. Neither effort can effect serious change in our energy patterns without marked improvements in electrical energy storage, with electrochemical energy storage in batteries and electrochemical capacitors serving as key components of any plausible scenario. 1, 2 Consumer expectations of convenience and long-lived portable power further drive the need to push these old devices onto a new performance curve. This issue of MRS Bulletin addresses the significant advances occurring in research laboratories around the world as old electrode materials and designs are re-envisioned, and abandoned materials of the past are reinvigorated by arranging matter and function on the nanoscale to bring batteries and electrochemical capacitors into the 21st century. C1 [Rolison, Debra R.] USN, Res Lab, Washington, DC 20375 USA. [Nazar, Linda F.] Univ Waterloo, Dept Chem, Waterloo, ON N2L 3G1, Canada. [Nazar, Linda F.] Univ Waterloo, Dept Elect Engn, Waterloo, ON N2L 3G1, Canada. RP Rolison, DR (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM rolison@nrl.navy.mil; lfnazar@uwaterloo.ca RI Nazar, Linda/H-2736-2014 OI Nazar, Linda/0000-0002-3314-8197 FU U.S. Office of Naval Research; Natural Science and Engineering Research Council of Canada FX The authors acknowledge the support of the U.S. Office of Naval Research (D.R.R.) and the Natural Science and Engineering Research Council of Canada (L.F.N.) for their respective programs in nanomaterials and electrochemical energy storage. The authors also thank Megan B. Sassin of the U.S. Naval Research Laboratory for preparing Figures 2 and 4 NR 48 TC 54 Z9 56 U1 5 U2 53 PU CAMBRIDGE UNIV PRESS PI NEW YORK PA 32 AVENUE OF THE AMERICAS, NEW YORK, NY 10013-2473 USA SN 0883-7694 J9 MRS BULL JI MRS Bull. PD JUL PY 2011 VL 36 IS 7 BP 486 EP 493 DI 10.1557/mrs.2011.136 PG 8 WC Materials Science, Multidisciplinary; Physics, Applied SC Materials Science; Physics GA 798XW UT WOS:000293246500007 ER PT J AU Long, JW Belanger, D Brousse, T Sugimoto, W Sassin, MB Crosnier, O AF Long, Jeffrey W. Belanger, Daniel Brousse, Thierry Sugimoto, Wataru Sassin, Megan B. Crosnier, Olivier TI Asymmetric electrochemical capacitors-Stretching the limits of aqueous electrolytes SO MRS BULLETIN LA English DT Article ID RUTHENIC ACID NANOSHEETS; POROUS CARBON MATERIALS; SURFACE REDOX REACTION; ENERGY-STORAGE; CHARGE-STORAGE; ACTIVATED CARBON; MANGANESE OXIDE; THIN-FILM; IMPEDANCE SPECTROSCOPY; HYBRID SUPERCAPACITOR AB Ongoing technological advances in such disparate areas as consumer electronics, transportation, and energy generation and distribution are often hindered by the capabilities of current energy storage/conversion systems, thereby driving the search for high-performance power sources that are also economically viable, safe to operate, and have limited environmental impact. Electrochemical capacitors (ECs) are a class of energy-storage devices that fill the gap between the high specific energy of batteries and the high specific power of conventional electrostatic capacitors. The most widely available commercial EC, based on a symmetric configuration of two high-surface-area carbon electrodes and a nonaqueous electrolyte, delivers specific energies of up to similar to 6 Whkg(-1) with sub-second response times. Specific energy can be enhanced by moving to asymmetric configurations and selecting electrode materials (e.g., transition metal oxides) that store charge via rapid and reversible faradaic reactions. Asymmetric EC designs also circumvent the main limitation of aqueous electrolytes by extending their operating voltage window beyond the thermodynamic 1.2 V limit to operating voltages approaching similar to 2 V, resulting in high-performance ECs that will satisfy the challenging power and energy demands of emerging technologies and in a more economically and environmentally friendly form than conventional symmetric ECs and batteries. C1 [Long, Jeffrey W.; Sassin, Megan B.] USN, Res Lab, Washington, DC 20375 USA. [Belanger, Daniel] Univ Quebec, Dept Chim, Montreal, PQ H3C 3P8, Canada. [Brousse, Thierry; Crosnier, Olivier] Univ Nantes, F-44035 Nantes, France. [Sugimoto, Wataru] Shinshu Univ, Ueda, Nagano 3868567, Japan. RP Long, JW (reprint author), USN, Res Lab, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM jeffrey.long@nrl.navy.mil; belanger.daniel@uqam.ca; thierry.brousse@univ-nantes.fr; wsugi@shinshu-u.ac.jp; megan.sassin@nrl.navy.mil; olivier.crosnier@univ-nantes.fr RI Sugimoto, Wataru/E-2041-2011 OI Sugimoto, Wataru/0000-0003-3868-042X FU U.S. Office of Naval Research; Natural Science and Engineering Research Council of Canada; Ministere Francais des Affaires Etrangeres of France; Ministere des Relations Internationales of Quebec; ABHYS French ANR FX J. Long and M. Sassin acknowledge the financial support of the U.S. Office of Naval Research. D. Belanger acknowledges the financial support of the Natural Science and Engineering Research Council of Canada. The Ministere Francais des Affaires Etrangeres of France and the Ministere des Relations Internationales of Quebec are also greatly acknowledged for supporting this work. Part of the work contributed by O. Crosnier and T. Brousse was performed under the frame-work of the ABHYS French ANR project, whose support is also acknowledged. The authors gratefully acknowledge John R. Miller (JME, Inc.) for helpful discussions regarding the technical content of this article. NR 110 TC 148 Z9 150 U1 18 U2 140 PU CAMBRIDGE UNIV PRESS PI NEW YORK PA 32 AVENUE OF THE AMERICAS, NEW YORK, NY 10013-2473 USA SN 0883-7694 J9 MRS BULL JI MRS Bull. PD JUL PY 2011 VL 36 IS 7 BP 513 EP 522 DI 10.1557/mrs.2011.137 PG 10 WC Materials Science, Multidisciplinary; Physics, Applied SC Materials Science; Physics GA 798XW UT WOS:000293246500010 ER PT J AU Willett, RM Marcia, RF Nichols, JM AF Willett, Rebecca M. Marcia, Roummel F. Nichols, Jonathan M. TI Compressed sensing for practical optical imaging systems: a tutorial SO OPTICAL ENGINEERING LA English DT Article DE compressed sensing; sampling; image reconstruction; inverse problems; computational imaging; infrared; coded aperture imaging; optimization ID SPARSE REPRESENTATIONS; UNCERTAINTY PRINCIPLES; SIGNAL RECONSTRUCTION; GEOMETRIC FRAMEWORK; RANDOM PROJECTIONS; L(1) MINIMIZATION; INVERSE PROBLEMS; RECOVERY; ALGORITHMS; NOISE AB The emerging field of compressed sensing has potentially powerful implications for the design of optical imaging devices. In particular, compressed sensing theory suggests that one can recover a scene at a higher resolution than is dictated by the pitch of the focal plane array. This rather remarkable result comes with some important caveats however, especially when practical issues associated with physical implementation are taken into account. This tutorial discusses compressed sensing in the context of optical imaging devices, emphasizing the practical hurdles related to building such devices, and offering suggestions for overcoming these hurdles. Examples and analysis specifically related to infrared imaging highlight the challenges associated with large format focal plane arrays and how these challenges can be mitigated using compressed sensing ideas. (C) 2011 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.3596602] C1 [Willett, Rebecca M.] Duke Univ, Durham, NC 27708 USA. [Marcia, Roummel F.] Univ Calif, Merced, CA 95343 USA. [Nichols, Jonathan M.] USN, Res Lab, Washington, DC 20375 USA. RP Willett, RM (reprint author), Duke Univ, Durham, NC 27708 USA. EM willett@duke.edu RI Willett, Rebecca/G-6930-2012 FU NSF [CCF-06-43947, DMS-08-11062]; DARPA [HR0011-09-1-0036]; NGA [HM1582-10-1-0002]; AFRL [FA8650-07-D-1221] FX The authors would like to thank Zachary Harmany for sharing his sparse reconstruction algorithms for compressive coded apertures. This work was supported by NSF CAREER Awards CCF-06-43947, DMS-08-11062, DARPA Grant No. HR0011-09-1-0036, NGA Award HM1582-10-1-0002, and AFRL Grant FA8650-07-D-1221. NR 100 TC 63 Z9 74 U1 4 U2 42 PU SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98225 USA SN 0091-3286 EI 1560-2303 J9 OPT ENG JI Opt. Eng. PD JUL PY 2011 VL 50 IS 7 AR 072601 DI 10.1117/1.3596602 PG 13 WC Optics SC Optics GA 797XZ UT WOS:000293164700019 ER PT J AU Halain, JP Eyles, CJ Mazzoli, A Bewsher, D Davies, JA Mazy, E Rochus, P Defise, JM Davis, CJ Harrison, RA Crothers, SR Brown, DS Korendyke, C Moses, JD Socker, DG Howard, RA Newmark, JS AF Halain, J. -P. Eyles, C. J. Mazzoli, A. Bewsher, D. Davies, J. A. Mazy, E. Rochus, P. Defise, J. M. Davis, C. J. Harrison, R. A. Crothers, S. R. Brown, D. S. Korendyke, C. Moses, J. D. Socker, D. G. Howard, R. A. Newmark, J. S. TI Straylight-Rejection Performance of the STEREO HI Instruments SO SOLAR PHYSICS LA English DT Article DE Straylight; Lens barrel rejection; Mean solar brightness; Off-pointing ID HELIOSPHERIC IMAGER; MISSION AB The SECCHI Heliospheric Imager (HI) instruments on-board the STEREO spacecraft have been collecting images of solar wind transients, including coronal mass ejections, as they propagate through the inner heliosphere since the beginning of 2007. The scientific use of the images depends critically on the performance of the instruments and its evolution over time. One of the most important factors affecting the performance of the instrument is the rejection of straylight from the Sun and from other bright objects located both within and outside the HI fields of view. This paper presents an analysis of the evolution of the straylight-rejection performance of the HI instrument on each of the two STEREO spacecraft over the three first years of the mission. The straylight level has been evaluated and expressed in mean solar brightness units, in which such scientific observations are usually quoted, using photometric conversion factors. C1 [Halain, J. -P.; Mazzoli, A.; Mazy, E.; Rochus, P.] Univ Liege, Ctr Spatial Liege, B-4031 Angleur, Belgium. [Eyles, C. J.] Univ Valencia, Lab Proc Imagenes, Valencia 46071, Spain. [Bewsher, D.; Brown, D. S.] Univ Cent Lancashire, Jeremiah Horrocks Inst, Preston PR1 2HE, Lancs, England. [Defise, J. M.] Univ Liege, Inst Astrophys & Geophys, B-4000 Liege, Belgium. [Eyles, C. J.; Davies, J. A.; Davis, C. J.; Harrison, R. A.; Crothers, S. R.] STFC Rutherford Appleton Lab, RAL Space, Didcot OX11 0QX, Oxon, England. [Korendyke, C.; Moses, J. D.; Socker, D. G.; Howard, R. A.; Newmark, J. S.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. [Newmark, J. S.] NASA Headquarters, Washington, DC 20546 USA. RP Halain, JP (reprint author), Univ Liege, Ctr Spatial Liege, Ave Pre Aily, B-4031 Angleur, Belgium. EM jphalain@ulg.ac.be RI Scott, Christopher/H-8664-2012; OI Scott, Christopher/0000-0001-6411-5649; Brown, Daniel/0000-0002-1618-8816; Bewsher, Danielle/0000-0002-6351-5170 FU NASA; PPARC; BELSPO FX The Heliospheric Imager (HI) instrument was developed by a collaboration which included the University of Birmingham (UB) and the Rutherford Appleton Laboratory (RAL), both in the UK, the Center Spatial de Liege (CSL), in Belgium, and the Naval Research Laboratory (NRL), in the US. We thank the US institutions, funded by NASA; the UK institutions, funded by PPARC; and the Belgian institutions, funded by BELSPO. We also thank the referees and the editor for their constructive comments. NR 12 TC 3 Z9 3 U1 0 U2 1 PU SPRINGER PI DORDRECHT PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS SN 0038-0938 EI 1573-093X J9 SOL PHYS JI Sol. Phys. PD JUL PY 2011 VL 271 IS 1-2 BP 197 EP 218 DI 10.1007/s11207-011-9800-z PG 22 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 797QT UT WOS:000293143100012 ER PT J AU Liu, SF Schulze, JP Herr, L Weekley, JD Zhu, B Osdol, NV Plepys, D Wan, MK AF Liu, Shaofeng Schulze, Jurgen P. Herr, Laurin Weekley, Jeffrey D. Zhu, Bing Osdol, Natalie V. Plepys, Dana Wan, Mike TI CineGrid Exchange: A workflow-based peta-scale distributed storage platform on a high-speed network SO FUTURE GENERATION COMPUTER SYSTEMS-THE INTERNATIONAL JOURNAL OF GRID COMPUTING AND ESCIENCE LA English DT Article DE CineGrid Exchange; Digital archiving; 4K; Distributed storage; IRODS AB The Academy of Motion Picture Arts and Sciences (AMPAS) report "The Digital Dilemma" describes the issues caused by the rapid increase of storage requirements for long-term preservation and access of high quality digital media content. As one of the research communities focusing on very high quality digital content, CineGrid addresses these issues by building a global-scale distributed storage platform suitable for handling high quality digital media, which we call CineGrid Exchange (CX). Today, the CX connects seven universities and research laboratories in five countries, managing 400TB of storage, of which 250TB are dedicated to CineGrid. All of these sites are interconnected through a 10 Gbps dedicated optical network. The CX distributed repository holds digital motion pictures at HD, 2K and 4K resolutions, digital still images and digital audio in various formats. The goals of the CX are: (1) providing a 10 Gbps interconnected distributed platform for the CineGrid community to study digital content related issues, e.g., digital archiving, the movie production process, and network transfer/streaming protocols; (2) building a tool with which people can securely store, easily share and transfer very high definition digital content worldwide for exhibition and real-time collaboration; (3) automating digital policies through middleware and metadata management. In this publication, we introduce the architecture of the CX, resources managed by the CX and the implementation of the first series of CX management policies using the iRODS programmable middleware. We evaluate the first phase of CX platform implementation. We show that the CX has the potential to be a reliable and scalable digital management system. Published by Elsevier B.V. C1 [Liu, Shaofeng] Univ Calif San Diego, Dept Comp Sci & Engn, La Jolla, CA 92093 USA. [Liu, Shaofeng; Schulze, Jurgen P.] UC San Diego, Calif Inst Telecommun & Informat Technol Calit2, La Jolla, CA USA. [Herr, Laurin; Osdol, Natalie V.] Pacific Interface Inc, Oakland, CA USA. [Weekley, Jeffrey D.] USN, Postgrad Sch, MOVES Inst, Monterey, CA USA. [Zhu, Bing; Wan, Mike] Univ Calif San Diego, Inst Neural Computat, La Jolla, CA 92093 USA. [Plepys, Dana] Univ Illinois, Elect Visualizat Lab, Dept Comp Sci, Chicago, IL USA. RP Liu, SF (reprint author), Univ Calif San Diego, Dept Comp Sci & Engn, La Jolla, CA 92093 USA. EM s8liu@cs.ucsd.edu; jschulze@soe.ucsd.edu; laurin@pacific-interface.com; jdweekley@nps.edu; bizhu@ucsd.edu; vanosdol@pacific-interface.com; dana@evl.uic.edu; mwan@sdsc.edu NR 14 TC 3 Z9 3 U1 0 U2 5 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0167-739X J9 FUTURE GENER COMP SY JI Futur. Gener. Comp. Syst. PD JUL PY 2011 VL 27 IS 7 SI SI BP 966 EP 976 DI 10.1016/j.future.2010.11.017 PG 11 WC Computer Science, Theory & Methods SC Computer Science GA 795AJ UT WOS:000292943600011 ER PT J AU Jankosky, CJ Hooper, TI Granado, NS Scher, A Gackstetter, GD Boyko, EJ Smith, TC AF Jankosky, Christopher J. Hooper, Tomoko I. Granado, Nisara S. Scher, Ann Gackstetter, Gary D. Boyko, Edward J. Smith, Tyler C. CA Millennium Cohort Study Team TI Headache Disorders in the Millennium Cohort: Epidemiology and Relations With Combat Deployment SO HEADACHE LA English DT Article DE migraine; headache symptom; incidence; cohort study; military personnel ID POSTTRAUMATIC-STRESS-DISORDER; HEALTH-CARE USE; US MILITARY; UNITED-STATES; MIGRAINE; PREVALENCE; COMORBIDITY; IMPACT; PAIN; ALCOHOL AB Objective.-Characterize migraine and other headache disorders within a large population-based US military cohort, with an emphasis on the temporal association between military deployment and exposure to combat. Background.-Little research has been published on the prevalence of headache disorders in the US military population, especially in relation to overseas deployments and exposure to combat. A higher than expected prevalence of migraine has previously been reported among deployed US soldiers in Iraq, suggesting an association. Headache disorders, including migraine, could have important effects on the performance of service members. Methods.-A total of 77,047 US active-duty, Reserve, and National Guard members completed a baseline questionnaire between July 2001 to June 2003 for the Millennium Cohort Study. Headache disorders were assessed using the following survey-based measures: self-reported history of provider-diagnosed migraine, recurrent severe headache within the past year, and recent headaches/bothered a lot within the past 4 weeks. Follow-up surveys were completed on average 3 years after baseline (mean = 2.7 years; range = 11.4 months to 4.5 years). Results.-The overall male and female prevalence of self-reported headache conditions at baseline were: provider-diagnosed migraine, 6.9% and 20.9%, respectively; recurrent severe headache, 9.4% and 22.3%, respectively; and bothered a lot by headaches, 3.4% and 10.4%, respectively. Combat deployers had significantly higher odds of any new-onset headache disorders than non-deployers (adjusted odds ratios = 1.72 for men, 1.84 for women; 95% confidence intervals, 1.55-1.90 for men, 1.55-2.18 for women), while deployers without combat exposure did not. Conclusions.-Deployed personnel with reported combat exposure appear to represent a higher risk group for new-onset headache disorders. The identification of populations at higher risk of development of headache provides support for targeted interventions. C1 [Jankosky, Christopher J.; Hooper, Tomoko I.] Uniformed Serv Univ Hlth Sci, Dept Prevent Med & Biometr, Bethesda, MD 20814 USA. [Granado, Nisara S.; Smith, Tyler C.] USN, Dept Deployment Hlth Res, Res Ctr, San Diego, CA 92152 USA. [Gackstetter, Gary D.] Analyt Serv Inc, Arlington, VA USA. [Boyko, Edward J.] Seattle Epidemiol Res & Informat Ctr, Dept Vet Affairs Puget Sound Hlth Care Syst, Seattle, WA USA. RP Jankosky, CJ (reprint author), Uniformed Serv Univ Hlth Sci, Dept Prevent Med & Biometr, 4301 Jones Bridge Rd, Bethesda, MD 20814 USA. EM cjankosky@usuhs.mil FU United States Army Medical Research and Materiel Command (Fort Detrick, MD, USA); US Department of Defense [60002] FX The Millennium Cohort Study is funded through the Military Operational Medicine Research Program, United States Army Medical Research and Materiel Command (Fort Detrick, MD, USA).; This work was supported by the US Department of Defense under Work Unit No. 60002. The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the Navy, Department of Defense, or the US Government. Approved for public release; distribution is unlimited. NR 34 TC 12 Z9 12 U1 0 U2 1 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 0017-8748 J9 HEADACHE JI Headache PD JUL-AUG PY 2011 VL 51 IS 7 BP 1098 EP 1111 DI 10.1111/j.1526-4610.2011.01914.x PG 14 WC Clinical Neurology SC Neurosciences & Neurology GA 793ZD UT WOS:000292862100005 PM 21675968 ER PT J AU Deschamps, JR Frisch, M Parrish, D AF Deschamps, Jeffrey R. Frisch, Mark Parrish, Damon TI Thermal Expansion of HMX SO JOURNAL OF CHEMICAL CRYSTALLOGRAPHY LA English DT Article DE 1,3,5,7-tetranitro-1,3,5,7-tetrazocane; HMX, anisotropic; Thermal expansion ID CRYSTAL-STRUCTURE; IGNITION; FORM AB Thermal expansion of the beta-phase of 1,3,5, 7-tetranitro-1,3,5,7-tetrazocane (beta-HMX, C(4)H(8)N(8)O(8)) was studied in the temperature range of -150 to 30 degrees C. beta-HMX is monoclinic (a = 6.5255(10) angstrom, b = 11.0369(18) angstrom, c = 7.3640(12) angstrom, and beta = 102.67(1)degrees), space group P2(1)/n. On cooling from room temperature to -150 degrees C the crystal under goes an anisotropic contraction with the a-axis virtually unchanged while the b and c axes contract by approximately 1.8 and 0.6% respectively. The disproportionate change in the a and c axes results in approximately a 0.4% change in the beta angle. Despite the large differences in expansion along the different axes no phase change was observed. C1 [Deschamps, Jeffrey R.; Frisch, Mark; Parrish, Damon] USN, Res Lab, Washington, DC 20375 USA. RP Deschamps, JR (reprint author), USN, Res Lab, Code 6930,4555 Overlook Ave, Washington, DC 20375 USA. EM deschamps@nrl.navy.mil RI G, Neela/H-3016-2014; OI Deschamps, Jeffrey/0000-0001-5845-0010 FU Office of Naval Research; Naval Research Laboratory FX This research was supported in part by the Office of Naval Research and the Naval Research Laboratory. The authors would like to thank Dr. Anthony Malanoski for his assistance in assessing how errors in the unit cell determination affect the calculated expansion coefficients. The views expressed herein are those of the authors and do not reflect those of the US Navy or the US Department of Defense. NR 15 TC 19 Z9 20 U1 0 U2 7 PU SPRINGER/PLENUM PUBLISHERS PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1074-1542 J9 J CHEM CRYSTALLOGR JI J. Chem. Crystallogr. PD JUL PY 2011 VL 41 IS 7 BP 966 EP 970 DI 10.1007/s10870-011-0026-6 PG 5 WC Crystallography; Spectroscopy SC Crystallography; Spectroscopy GA 793RS UT WOS:000292841400008 ER PT J AU Deschamps, JR Straessler, NA AF Deschamps, Jeffrey R. Straessler, Nicholas A. TI Structure of O-Methyl-trinitrophloroglucinol Derivatives SO JOURNAL OF CHEMICAL CRYSTALLOGRAPHY LA English DT Article DE 5-Methoxystyphnic acid; 3,5-Dimethoxypicric acid; 1,3,5-Trimethoxy-2,4,6-trinitrobenzene; Energetic compounds ID CRYSTAL; 1,3,5-TRIAMINO-2,4,6-TRINITROBENZENE; NITRATION AB The structures of mono, di, and tri-O-methyl derivatives of 2,4,6-trinitrophloroglucinol were determined by single crystal X-ray diffraction. As the number of methoxy groups increased from one to three the unit cell volume increased at a rate greater than the formula weight of the asymmetric unit such that crystal density decreased from 1.823 to 1.619 Mg/m(3). The structural data reveal that the decreased density is related to increased angles between the plane of the phenyl ring and the planes defined by the nitro and methoxy groups, as well as fewer inter molecular interactions. C1 [Deschamps, Jeffrey R.] USN, Res Lab, Washington, DC 20375 USA. [Straessler, Nicholas A.] ATK Aerosp Syst, Res & Dev, Brigham City, UT 84302 USA. RP Deschamps, JR (reprint author), USN, Res Lab, Code 6930,4555 Overlook Ave, Washington, DC 20375 USA. EM deschamps@nrl.navy.mil RI G, Neela/H-3016-2014; OI Deschamps, Jeffrey/0000-0001-5845-0010 FU Department of Defense [WP 1582]; ATK Aerospace Systems [W912HQ-07-C-0018]; Naval Research Laboratory FX This research was supported by the Department of Defense: Strategic Environmental Research and Development Program (SERDP Project # WP 1582) performed under ATK Aerospace Systems Contract W912HQ-07-C-0018, and by the Naval Research Laboratory. NR 18 TC 2 Z9 2 U1 0 U2 1 PU SPRINGER/PLENUM PUBLISHERS PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1074-1542 J9 J CHEM CRYSTALLOGR JI J. Chem. Crystallogr. PD JUL PY 2011 VL 41 IS 7 BP 971 EP 975 DI 10.1007/s10870-011-0027-5 PG 5 WC Crystallography; Spectroscopy SC Crystallography; Spectroscopy GA 793RS UT WOS:000292841400009 ER PT J AU MacMahan, J Reniers, A Brown, J Brander, R Thornton, E Stanton, T Brown, J Carey, W AF MacMahan, Jamie Reniers, Ad Brown, Jenna Brander, Rob Thornton, Ed Stanton, Tim Brown, Jeff Carey, Wendy TI An Introduction to Rip Currents Based on Field Observations SO JOURNAL OF COASTAL RESEARCH LA English DT Editorial Material AB Rip currents are fascinating, natural, surf zone phenomena that occur daily on many beaches throughout the world. My colleagues, students, advisors, and I have been studying rip currents for more than 10 years and have performed more than 10 comprehensive field experiments on various beaches throughout the world using different observational techniques and model simulations to improve our understanding and prediction of rip currents. We have written a series of scientific articles describing the intricacies and complexities of rip current behavior using statistical and mathematical equations. These manuscripts are typically published in professional journals, which often do not communicate our results to those who would benefit from the information-the beachgoing public and ocean swimmers. Herein, we summarize our findings to help people of all ages gain a better understanding of currents at the coast. C1 [MacMahan, Jamie; Brown, Jenna; Thornton, Ed; Stanton, Tim] USN, Postgrad Sch, Dept Oceanog, Monterey, CA 93943 USA. [Reniers, Ad] Univ Miami, Rosenstiel Sch Marine & Atmospher Sci, Miami, FL 33149 USA. [Brander, Rob] Univ New S Wales, Sch Biol Earth & Environm Sci, Sydney, NSW 2052, Australia. [Brown, Jeff] LEAP Engn LLC, Coastal Engn Div, Galveston, TX 77550 USA. [Carey, Wendy] Univ Delaware, Delaware Sea Grant Coll Program, Lewes, DE 19958 USA. RP MacMahan, J (reprint author), USN, Postgrad Sch, Dept Oceanog, Monterey, CA 93943 USA. EM jhmacmah@nps.edu; areniers@rsmas.miami.edu; jeff.brown@leapengineering.com jeff.brown@leapengineering.com; rbrander@unsw.edu.au; thornton@nps.edu; stanton@nps.edu; jeff.brown@leapengineering.com jeff.brown@leapengineering.com NR 0 TC 7 Z9 7 U1 0 U2 16 PU COASTAL EDUCATION & RESEARCH FOUNDATION PI LAWRENCE PA 810 EAST 10TH STREET, LAWRENCE, KS 66044 USA SN 0749-0208 J9 J COASTAL RES JI J. Coast. Res. PD JUL PY 2011 VL 27 IS 4 BP III EP VI DI 10.2112/JCOASTRES-D-11-00024.1 PG 4 WC Environmental Sciences; Geography, Physical; Geosciences, Multidisciplinary SC Environmental Sciences & Ecology; Physical Geography; Geology GA 795DL UT WOS:000292951600001 ER PT J AU McCarthy, E Moretti, D Thomas, L DiMarzio, N Morrissey, R Jarvis, S Ward, J Izzi, A Dilley, A AF McCarthy, Elena Moretti, David Thomas, Len DiMarzio, Nancy Morrissey, Ronald Jarvis, Susan Ward, Jessica Izzi, Annamaria Dilley, Ashley TI Changes in spatial and temporal distribution and vocal behavior of Blainville's beaked whales (Mesoplodon densirostris) during multiship exercises with mid-frequency sonar SO MARINE MAMMAL SCIENCE LA English DT Article DE Blainville's beaked whale; mid-frequency; sonar; Mesoplodon densirostris; mass stranding; AUTEC ID ZIPHIUS-CAVIROSTRIS; DIVING BEHAVIOR; ECHOLOCATION; HAWAII; OCEAN AB The number and distribution of vocalizing groups of Blainville's beaked whales (Mesoplodon densirostris) were analyzed before, during, and after multiship mid-frequency active sonar operations at the US Navy's Atlantic Undersea Test and Evaluation Center (AUTEC) in the Bahamas. Groups of foraging animals were isolated by detecting their echolocation clicks using an array of bottom-mounted hydrophones. Two data sets were evaluated consisting of 115 and 240 h of acoustic data in May 2007 and 2008, respectively. Vocal activity was observed to decline during active sonar exercises and increase upon cessation of sonar transmissions in both data sets. Vocal activity did not recover to preexposure levels in the postexposure time period in 2007 nor in the initial postexposure period in the 2008 data set. Clicks detected during sonar operations were generally found to be on the periphery of the hydrophone field and vocal durations declined for those groups that remained on the range in that time period. Receive levels were calculated for several vocal groups of whales and indicated that animals continued to forage when exposed to sonar at levels as high as 157 dB re: mu Pa. C1 [McCarthy, Elena; Moretti, David; DiMarzio, Nancy; Morrissey, Ronald; Jarvis, Susan; Ward, Jessica; Izzi, Annamaria; Dilley, Ashley] USN, UnderseaWarfare Ctr, Newport, RI 02840 USA. [Thomas, Len] Univ St Andrews, Ctr Res Ecol & Environm Modeling, St Andrews KY16 9LZ, Fife, Scotland. RP McCarthy, E (reprint author), USN, UnderseaWarfare Ctr, Code 74, Newport, RI 02840 USA. EM emccarthy@whoi.edu FU Naval Operations' Environmental Readiness Division; Office of Naval Research FX We thank Peter Tyack and Mark Johnson of the Woods Hole Oceanographic Institution for their support and expertise with DTAGs, Diane Claridge and her staff at the Bahamas Marine Mammal Research Organization, Ian Boyd at the Sea Mammal Research Unit at the University of St Andrews, and Chris Clark at Cornell University's Laboratory of Ornithology. Thanks also to Bert Neales, Jr. at the Naval Undersea Warfare Center for his expertise with NEMO, Bill Sutphin for his knowledge of AUTEC's ship tracking system, and the interns there who aided in the creation of this manuscript, Margaret Prior and Carroll-Anne Ciminello. Special thanks are extended to Holly Turton who edited our manuscript. We would especially like to acknowledge the very helpful and thorough comments by three anonymous reviewers. The Chief of Naval Operations' Environmental Readiness Division and the Office of Naval Research's Marine Mammals and Biological Oceanography Program provided funding and guidance for this work. NR 26 TC 24 Z9 24 U1 5 U2 58 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0824-0469 J9 MAR MAMMAL SCI JI Mar. Mamm. Sci. PD JUL PY 2011 VL 27 IS 3 BP E206 EP E226 DI 10.1111/j.1748-7692.2010.00457.x PG 21 WC Marine & Freshwater Biology; Zoology SC Marine & Freshwater Biology; Zoology GA 793LU UT WOS:000292825200005 ER PT J AU Berck, P Lipow, J AF Berck, Peter Lipow, Jonathan TI Military Conscription and the (Socially) Optimal Number of Boots on the Ground SO SOUTHERN ECONOMIC JOURNAL LA English DT Article ID DRAFT AB In this article, we develop a model of military manpower mobilization. We use the model to evaluate the efficacy of volunteer- and conscription-based manpower systems within a framework of social welfare maximization. We find that neither conscription nor a volunteer approach is likely to be "first best" because of asymmetries of information and constraints on the military pay structure. We then modify the general model by considering the possibility that recruits with high civilian productivity are also more capable soldiers and find that, under such circumstances, conscription may be a more benign form of manpower mobilization than previously understood. We also consider and evaluate various alternatives available to militaries attempting to minimize the welfare losses associated with manpower mobilization. C1 [Berck, Peter] Univ Calif Berkeley, Dept Agr & Resource Econ & Policy, Berkeley, CA 94720 USA. [Lipow, Jonathan] USN, Def Resource Management Inst, Postgrad Sch, Monterey, CA 93943 USA. RP Berck, P (reprint author), Univ Calif Berkeley, Dept Agr & Resource Econ & Policy, Berkeley, CA 94720 USA. EM pberck@berkeley.edu; jlipow@nps.edu NR 19 TC 3 Z9 3 U1 1 U2 5 PU UNIV NORTH CAROLINA PI CHAPEL HILL PA SOUTHERN ECONOMIC JOURNAL, CHAPEL HILL, NC 27514 USA SN 0038-4038 J9 SOUTH ECON J JI South. Econ. J. PD JUL PY 2011 VL 78 IS 1 BP 95 EP 106 PG 12 WC Economics SC Business & Economics GA 793XB UT WOS:000292856100007 ER PT J AU Hollis-Perry, M AF Hollis-Perry, Monique TI The Pathologist: Part of the Team SO ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE LA English DT Letter C1 USN, Naval Med Ctr San Diego, San Diego, CA 92134 USA. RP Hollis-Perry, M (reprint author), USN, Naval Med Ctr San Diego, San Diego, CA 92134 USA. NR 0 TC 0 Z9 0 U1 0 U2 2 PU COLLEGE AMER PATHOLOGISTS PI NORTHFIELD PA C/O KIMBERLY GACKI, 325 WAUKEGAN RD, NORTHFIELD, IL 60093-2750 USA SN 0003-9985 J9 ARCH PATHOL LAB MED JI Arch. Pathol. Lab. Med. PD JUL PY 2011 VL 135 IS 7 BP 823 EP 823 PG 1 WC Medical Laboratory Technology; Medicine, Research & Experimental; Pathology SC Medical Laboratory Technology; Research & Experimental Medicine; Pathology GA 790PW UT WOS:000292602700001 PM 21732767 ER PT J AU Graf, MA Sprenger, M Moore, RW AF Graf, Michael A. Sprenger, Michael Moore, Richard W. TI Central European tornado environments as viewed from a potential vorticity and Lagrangian perspective SO ATMOSPHERIC RESEARCH LA English DT Article DE Europe; Tornado; Severe storm indicators; Forcing; Trajectory analysis ID LEVEL JET STREAKS; HEAVY PRECIPITATION; CLIMATOLOGY; REANALYSIS; PARAMETERS; SUPERCELL; OUTBREAK; FEATURES; STORMS; ALPS AB ECMWF analysis data in conjunction with infrared satellite imagery and surface weather analyses from the German Weather Service are used to investigate 15 significant central European tornadoes (F2 intensity on the Fujita scale) that occurred in 2005 and 2006. The primary goals of the work are to: (i) determine the typical synoptic and mesoscale environments that are conducive to European tornadogenesis; (ii) compare and contrast the said environments with those found in the central United States (US), with a specific focus on severe storm predictors: and (iii) elucidate a methodology for the real-time forecasting of these destructive storms that, in addition to the use of severe storm predictors, leans heavily on the potential vorticity (PV) and Lagrangian frameworks of analysis. With the caveats that there is significant case-to-case variability and the sample size is relatively small, the results illustrate that most European tornadoes form close to (within 200 km of) a distinct upper-level PV anomaly and a majority under the cyclonic side of an upper-level jet streak. Lower-level forcing, in the form of surface fronts, is also found to be present in a number of cases. With regards to severe storm predictors (convective available potential energy, storm-relative helicity and the energy helicity index), this study confirms the earlier findings that, while representative values for European tornadic environments are substantially lower than their US counterparts, they do provide useful predictive information in that their values tend to be markedly higher than the local, monthly climatology. A subsequent Lagrangian analysis that isolates the coherent air streams present in US and European tornadoes provides significant insight into the discrepancies in both the synoptic environments and the absolute magnitude of the severe storm predictors. Backward trajectories launched from the tornado genesis time and position, illustrate that low-level flow blocking by the Alps and the relatively-colder sea surface temperatures found over the Atlantic Ocean (in contrast to the Gulf of Mexico) play a primary role in reducing the dynamic and thermodynamic instabilities in European tornado environments. (C) 2011 Elsevier B.V. All rights reserved. C1 [Graf, Michael A.; Sprenger, Michael] Swiss Fed Inst Technol, Inst Atmospher & Climate Sci, Zurich, Switzerland. [Moore, Richard W.] USN, Postgrad Sch, Monterey, CA USA. RP Graf, MA (reprint author), Swiss Fed Inst Technol, Inst Atmospher & Climate Sci, Zurich, Switzerland. EM michael_arthur_graf@bluewin.ch NR 43 TC 8 Z9 8 U1 2 U2 11 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 0169-8095 J9 ATMOS RES JI Atmos. Res. PD JUL PY 2011 VL 101 IS 1-2 BP 31 EP 45 DI 10.1016/j.atmosres.2011.01.007 PG 15 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA 790WD UT WOS:000292620500003 ER PT J AU Linoski, A AF Linoski, Alexis TI E-books in Academic Libraries SO JOURNAL OF ACADEMIC LIBRARIANSHIP LA English DT Book Review C1 [Linoski, Alexis] USN Acad, Nimitz Lib, Annapolis, MD 21402 USA. RP Linoski, A (reprint author), USN Acad, Nimitz Lib, Annapolis, MD 21402 USA. EM linoski@usna.edu RI Linoski, Alexis/A-8396-2009 OI Linoski, Alexis/0000-0001-7307-8771 NR 1 TC 0 Z9 0 U1 0 U2 5 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 0099-1333 J9 J ACAD LIBR JI J. Acad. Librariansh. PD JUL PY 2011 VL 37 IS 4 BP 364 EP 364 DI 10.1016/j.acalib.2011.04.013 PG 1 WC Information Science & Library Science SC Information Science & Library Science GA 790XV UT WOS:000292625000014 ER PT J AU Chung, S Wheeler, V Myers-Ward, R Nyakiti, LO Eddy, CR Gaskill, DK Skowronski, M Picard, YN AF Chung, Suk Wheeler, Virginia Myers-Ward, Rachael Nyakiti, Luke O. Eddy, Charles R., Jr. Gaskill, D. Kurt Skowronski, Marek Picard, Yoosuf N. TI Secondary electron dopant contrast imaging of compound semiconductor junctions SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID N-JUNCTIONS; MICROSCOPE; SEM; EMISSION; UPDATE AB Secondary electron imaging combined with immersion lens and through-the-lens detection has been used to analyze various semiconductor junctions. Dopant contrast imaging was applied for multi-doped 4H-SiC, growth-interrupted n(+)/p and n/n(+) homoepitaxial interfaces, and an AlGaAs/GaAs p-n junction light-emitting diode structure. Dopant contrast was explained by the local variation in secondary electron escape energies resulting from the built-in potential difference. The effect of varying electron affinity on contrast for the heterostructures is also discussed. The contrast profile of the n-doped AlGaAs compared reasonably well to the simulated valence bandedge energy using a previously determined efficiency of dopant ionization. (C) 2011 American Institute of Physics. [doi:10.1063/1.3597785] C1 [Chung, Suk; Skowronski, Marek; Picard, Yoosuf N.] Carnegie Mellon Univ, Dept Mat Sci & Engn, Pittsburgh, PA 15213 USA. [Wheeler, Virginia; Myers-Ward, Rachael; Nyakiti, Luke O.; Eddy, Charles R., Jr.; Gaskill, D. Kurt] USN, Res Lab, Adv SiC Epitaxial Res Lab, Washington, DC 20375 USA. RP Chung, S (reprint author), Carnegie Mellon Univ, Dept Mat Sci & Engn, 5000 Forbes Ave, Pittsburgh, PA 15213 USA. EM suk.chung@intel.com RI Skowronski, Marek/A-8934-2011; OI Skowronski, Marek/0000-0002-2087-0068; Picard, Yoosuf/0000-0002-2853-5213 FU ONR [N000141010532]; ASEE FX This work was supported by ONR grant N000141010532. The authors acknowledge Professor Yong-Hang Zhang and Dr. Shane R. Johnson at Arizona State University for providing LED samples for SEM analysis. Work at NRL was also supported by ONR. Dr. Virginia Wheeler and Dr. Luke O. Nyakiti are grateful for postdoctoral support from ASEE. NR 27 TC 3 Z9 3 U1 0 U2 16 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0021-8979 EI 1089-7550 J9 J APPL PHYS JI J. Appl. Phys. PD JUL 1 PY 2011 VL 110 IS 1 AR 014902 DI 10.1063/1.3597785 PG 6 WC Physics, Applied SC Physics GA 792US UT WOS:000292776500138 ER PT J AU Nainani, A Yuan, Z Krishnamohan, T Bennett, BR Boos, JB Reason, M Ancona, MG Nishi, Y Saraswat, KC AF Nainani, Aneesh Yuan, Ze Krishnamohan, Tejas Bennett, Brian R. Boos, J. Brad Reason, Matthew Ancona, Mario G. Nishi, Yoshio Saraswat, Krishna C. TI InxGa1-xSb channel p-metal-oxide-semiconductor field effect transistors: Effect of strain and heterostructure design SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID WELL; PERFORMANCE; TRANSPORT; MOSFETS AB InxGa1-xSb is an attractive candidate for high performance III-V p-metal-oxide-semiconductor field effect transistors (pMOSFETs) due to its high bulk hole mobility that can be further enhanced with the use of strain. We fabricate and study InxGa1-xSb-channel pMOSFETs with atomic layer deposition Al2O3 dielectric and self-aligned source/drain formed by ion implantation. The effects of strain and heterostructure design for enhancing transistor performance are studied systematically. Different amounts of biaxial compression are introduced during MBE growth, and the effect of uniaxial strain is studied using wafer-bending experiments. Both surface and buried channel MOSFET designs are investigated. Buried (surface) channel InxGa1-xSb pMOSFETs with peak hole mobility of 910 (620) cm(2)/Vs and subthreshold swing of 120 mV/decade are demonstrated. Pulsed I-V measurements and low-temperature I-V measurements are used to investigate the physics in transistor characteristics. (C) 2011 American Institute of Physics. [doi:10.1063/1.3600220] C1 [Nainani, Aneesh; Yuan, Ze; Krishnamohan, Tejas; Nishi, Yoshio; Saraswat, Krishna C.] Stanford Univ, Ctr Integrated Syst, Dept Elect Engn, Stanford, CA 94305 USA. [Bennett, Brian R.; Boos, J. Brad; Reason, Matthew; Ancona, Mario G.] USN, Res Lab, Washington, DC 20375 USA. RP Nainani, A (reprint author), Stanford Univ, Ctr Integrated Syst, Dept Elect Engn, Stanford, CA 94305 USA. EM nainani@stanford.edu RI Bennett, Brian/A-8850-2008 OI Bennett, Brian/0000-0002-2437-4213 FU Intel Corporation; Office of Naval Research FX Aneesh Nainani would like to thank Intel Corporation for a PhD fellowship. This work was partially supported by the Office of Naval Research and Intel Corporation. NR 27 TC 25 Z9 25 U1 0 U2 9 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0021-8979 J9 J APPL PHYS JI J. Appl. Phys. PD JUL 1 PY 2011 VL 110 IS 1 AR 014503 DI 10.1063/1.3600220 PG 9 WC Physics, Applied SC Physics GA 792US UT WOS:000292776500124 ER PT J AU Lieske, J Cameron, B Drinkwine, B Goretzke, S Alemi, L Needham, K Ventura, J Ho, VT La Barge, DV AF Lieske, Jonathan Cameron, Brian Drinkwine, Benjamin Goretzke, Sean Alemi, Lily Needham, Kenneth Ventura, John Van Thong Ho La Barge, Donald V., III TI Surfer's Myelopathy-Demonstrated by Diffusion-Weighted Magnetic Resonance Imaging: A Case Report and Literature Review SO JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY LA English DT Review ID SPINAL-CORD INFARCTION; MRI AB The authors present a case of "surfer's myelopathy," a rarely described syndrome characterized by nontraumatic paraparesis/paraplegia in novice surfers and theorized to result from spinal cord ischemia secondary to surfing-related positional hyperextension. Imaging and clinical course of the youngest known affected individual are discussed, including evidence of acute spinal cord infarction on diffusion-weighted magnetic resonance imaging, a finding not previously described in the literature. C1 [Lieske, Jonathan; Drinkwine, Benjamin; Van Thong Ho; La Barge, Donald V., III] Naval Med Ctr Portsmouth, Dept Radiol, Portsmouth, VA 23708 USA. [Cameron, Brian] Naval Med Ctr Portsmouth, Dept Neurosurg, Portsmouth, VA 23708 USA. [Goretzke, Sean] Naval Med Ctr Portsmouth, Dept Pediat Neurol, Portsmouth, VA 23708 USA. [Alemi, Lily] Riverside Reg Med Ctr, Dept Family Med, Newport News, VA USA. [Needham, Kenneth] Naval Med Ctr Portsmouth, Dept Orthopaed Surg, Portsmouth, VA 23708 USA. [Ventura, John] Naval Med Ctr Portsmouth, Dept Emergency Med, Portsmouth, VA 23708 USA. RP Lieske, J (reprint author), Naval Med Ctr Portsmouth, Dept Radiol, 620 John Paul Jones Circle, Portsmouth, VA 23708 USA. EM Jonathan.lieske@med.navy.mil NR 12 TC 7 Z9 7 U1 0 U2 4 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0363-8715 J9 J COMPUT ASSIST TOMO JI J. Comput. Assist. Tomogr. PD JUL-AUG PY 2011 VL 35 IS 4 BP 492 EP 494 DI 10.1097/RCT.0b013e31821e277b PG 3 WC Radiology, Nuclear Medicine & Medical Imaging SC Radiology, Nuclear Medicine & Medical Imaging GA 792TR UT WOS:000292773800013 PM 21765307 ER PT J AU Boyarko, GA Romano, M Yakimenko, OA AF Boyarko, George A. Romano, Marcello Yakimenko, Oleg A. TI Time-Optimal Reorientation of a Spacecraft Using an Inverse Dynamics Optimization Method SO JOURNAL OF GUIDANCE CONTROL AND DYNAMICS LA English DT Article ID OPTIMAL 3-AXIS REORIENTATION; RIGID SPACECRAFT; MANEUVERS AB This paper proposes a rapid attitude trajectory generation method for satellite reorientation, which is suitable for both rest-to-rest and track-to-track maneuvers. The problem is first formulated and solved using academic software readily used for generating optimal guidance trajectories offline. Then, the problem is reformulated using a Bezier polynomial parametrization of the quaternion trajectory, which naturally satisfies the unit quaternion norm constraint. The parameters of the quaternion trajectory polynomial and of the speed profile are varied to arrive at a quasi-optimal solution that is both feasible and exactly matches the endpoint conditions specified in the problem. The reduction in the number of varied parameters due to the predetermined structure of the trajectory leads to a fast computational speed as well as a solution that satisfies the end constraints at each iteration. The paper includes numerical simulation results obtained for several cases. C1 [Boyarko, George A.; Romano, Marcello; Yakimenko, Oleg A.] USN, Postgrad Sch, Dept Mech & Aerosp Engn, Monterey, CA 93943 USA. RP Boyarko, GA (reprint author), USN, Postgrad Sch, Dept Mech & Aerosp Engn, Monterey, CA 93943 USA. EM gaboyark@nps.edu; mromano@nps.edu; oayakime@nps.edu RI Romano, Marcello/C-7972-2013 NR 24 TC 17 Z9 20 U1 2 U2 8 PU AMER INST AERONAUT ASTRONAUT PI RESTON PA 1801 ALEXANDER BELL DRIVE, STE 500, RESTON, VA 22091-4344 USA SN 0731-5090 J9 J GUID CONTROL DYNAM JI J. Guid. Control Dyn. PD JUL-AUG PY 2011 VL 34 IS 4 BP 1197 EP 1208 DI 10.2514/1.49449 PG 12 WC Engineering, Aerospace; Instruments & Instrumentation SC Engineering; Instruments & Instrumentation GA 792OV UT WOS:000292757300021 ER PT J AU Yan, H Gong, Q Park, CD Ross, IM D'Souza, CN AF Yan, Hui Gong, Qi Park, Chan D. Ross, I. Michael D'Souza, Christopher N. TI High-Accuracy Trajectory Optimization for a Trans-Earth Lunar Mission SO JOURNAL OF GUIDANCE CONTROL AND DYNAMICS LA English DT Article ID PSEUDOSPECTRAL METHOD; SINGULAR ARCS; LOW-THRUST; SEQUENCE; MODEL AB The trajectory optimization of a spacecraft subject to the gravitational effects of the moon, Earth, and sun are considered. The problem is how to achieve Earth-interface conditions from a low lunar orbit. Practical constraints of maximum thrust, fuel budget, and flight time generates a constrained, nonautonomous, nonlinear optimal control problem. Severe constraints on the fuel budget combined with high-accuracy demands on the endpoint conditions necessitate a high-accuracy solution to the trajectory optimization problem. The problem is first solved using the standard Legendre pseudospectral method. The optimality of the solution is verified by an application of the covector mapping principle. It is shown that the thrust structure consists of three finite burns with nearly linear steering-angle time histories. A singular arc is detected and is interpreted as a singular plane change maneuver. The Bellman pseudospectral method is then employed for mesh refinement to improve the accuracy of the solution. C1 [Yan, Hui; Gong, Qi] Univ Calif Santa Cruz, Dept Appl Math & Stat, Santa Cruz, CA 95064 USA. [Park, Chan D.; Ross, I. Michael] USN, Postgrad Sch, Dept Mech & Aerosp Engn, Monterey, CA 93943 USA. [D'Souza, Christopher N.] NASA, Lyndon B Johnson Space Ctr, EG6, Aerosci & Flight Mech Div, Houston, TX 77058 USA. RP Yan, H (reprint author), Univ Calif Santa Cruz, Dept Appl Math & Stat, Santa Cruz, CA 95064 USA. FU U.S. Naval Postgraduate School [N00244-10-1-0049] FX We gratefully acknowledge funding for this research provided in part by U.S. Naval Postgraduate School under Grant N00244-10-1-0049. We would like to thank one of the anonymous reviewers for independently validating our results. NR 38 TC 9 Z9 10 U1 1 U2 3 PU AMER INST AERONAUT ASTRONAUT PI RESTON PA 1801 ALEXANDER BELL DRIVE, STE 500, RESTON, VA 22091-4344 USA SN 0731-5090 J9 J GUID CONTROL DYNAM JI J. Guid. Control Dyn. PD JUL-AUG PY 2011 VL 34 IS 4 BP 1219 EP 1227 DI 10.2514/1.49237 PG 9 WC Engineering, Aerospace; Instruments & Instrumentation SC Engineering; Instruments & Instrumentation GA 792OV UT WOS:000292757300023 ER PT J AU Boyarko, G Yakimenko, O Romano, M AF Boyarko, George Yakimenko, Oleg Romano, Marcello TI Optimal Rendezvous Trajectories of a Controlled Spacecraft and a Tumbling Object SO JOURNAL OF GUIDANCE CONTROL AND DYNAMICS LA English DT Article; Proceedings Paper CT AIAA Guidance, Navigation and Control Conference CY AUG 10-13, 2009 CL Chicago, IL SP Amer Inst Aeronaut & Astronaut AB This paper formulates and solves the problem of minimum-time and minimum-energy optimal trajectories of rendezvous of a powered chaser and a passive tumbling target, in a circular orbit. Both translational and rotational dynamics are considered. In particular, ending conditions are imposed of matching the positions and velocities of two points of interest onboard the vehicles. A collision-avoidance condition is imposed as well. The optimal control problems are analytically formulated through the use of the Pontryagin minimum principle. The problems are then solved numerically, by using a direct collocation method based on the Gauss pseudospectral approach. Finally, the obtained solutions are verified through the minimum principle, solved by a shooting method. The simulation results show that the pseudospectral solver provides solutions very close to the optimal ones, except in the case of presence of singular arcs when it may not provide a feasible solution. The computational time needed by the pseudospectral solver is a small fraction of the one needed by the indirect approach, but it is still considerably too large to allow for its use in real-time onboard guidance. C1 [Boyarko, George; Yakimenko, Oleg] USN, Postgrad Sch, Dept Mech & Aerosp Engn, Code MAE Yk, Monterey, CA 93943 USA. [Romano, Marcello] USN, Postgrad Sch, Dept Mech & Aerosp Engn, Code MAE MR, Monterey, CA 93943 USA. RP Boyarko, G (reprint author), USN, Postgrad Sch, Dept Mech & Aerosp Engn, Code MAE Yk, Monterey, CA 93943 USA. EM gboyarko@nps.edu; oayakime@nps.edu; mromano@nps.edu RI Romano, Marcello/C-7972-2013 NR 16 TC 16 Z9 19 U1 1 U2 6 PU AMER INST AERONAUT ASTRONAUT PI RESTON PA 1801 ALEXANDER BELL DRIVE, STE 500, RESTON, VA 22091-4344 USA SN 0731-5090 J9 J GUID CONTROL DYNAM JI J. Guid. Control Dyn. PD JUL-AUG PY 2011 VL 34 IS 4 BP 1239 EP 1252 DI 10.2514/1.47645 PG 14 WC Engineering, Aerospace; Instruments & Instrumentation SC Engineering; Instruments & Instrumentation GA 792OV UT WOS:000292757300025 ER PT J AU McKenzie, R Porter, CK Cantrell, JA DeNearing, B O'Dowd, A Grahek, SL Sincock, SA Woods, C Sebeny, P Sack, DA Tribble, DR Bourgeois, AL Savarino, SJ AF McKenzie, Robin Porter, Chad K. Cantrell, Joyce A. DeNearing, Barbara O'Dowd, Aisling Grahek, Shannon L. Sincock, Stephanie A. Woods, Colleen Sebeny, Peter Sack, David A. Tribble, David R. Bourgeois, A. Louis Savarino, Stephen J. TI Volunteer Challenge With Enterotoxigenic Escherichia coli That Express Intestinal Colonization Factor Fimbriae CS17 and CS19 SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID DIARRHEA; IMMUNIZATION; INFECTIONS; RESPONSES; CHILDREN; VACCINE; COHORT; EGYPT AB Human challenges with enterotoxigenic Escherichia coli (ETEC) have broadened our understanding of this important enteropathogen. We report findings from the first challenge studies using ETEC-expressing colonization factor fimbria CS17 and CS19. LSN03-016011/A (LT, CS17) elicited a dose-dependent effect, with the upper dose (6 x 10(9) organisms) causing diarrhea in 88% of recipients. WS0115A (LTSTp, CS19) also showed a dose response, with a 44% diarrhea rate at 9 x 10(9) organisms. Both strains elicited homologous antifimbrial and anti-LT antibody seroconversion. These studies establish the relative pathogenicity of ETEC expressing newer class 5 fimbriae and suggest suitability of the LT|CS17-ETEC challenge model for interventional trials. C1 [Porter, Chad K.; Cantrell, Joyce A.; O'Dowd, Aisling; Sincock, Stephanie A.; Woods, Colleen; Savarino, Stephen J.] USN, Med Res Ctr, Enter Dis Dept, Infect Dis Directorate, Silver Spring, MD 20910 USA. [McKenzie, Robin] Johns Hopkins Univ, Dept Med, Div Infect Dis, Johns Hopkins Bayview Med Ctr, Baltimore, MD USA. [McKenzie, Robin; DeNearing, Barbara; Grahek, Shannon L.; Sack, David A.; Bourgeois, A. Louis] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Int Hlth, Ctr Immunizat Res, Baltimore, MD USA. [Sebeny, Peter] Natl Naval Med Ctr, Div Infect Dis, Dept Med, Bethesda, MD USA. [Tribble, David R.] Uniformed Serv Univ Hlth Sci, Dept Prevent Med & Biometr, Bethesda, MD 20814 USA. [Savarino, Stephen J.] Uniformed Serv Univ Hlth Sci, Dept Pediat, Bethesda, MD 20814 USA. RP Savarino, SJ (reprint author), USN, Med Res Ctr, Enter Dis Dept, Infect Dis Directorate, 503 Robert Grant Ave, Silver Spring, MD 20910 USA. EM stephen.savarino@med.navy.mil FU Peer-Reviewed Medical Research Program [W81XWH-04-1-0067]; Johns Hopkins University School of Medicine General Clinical Research Center (National Center for Research Resources, National Institutes of Health) [M01-RR00052] FX This work was supported by the Peer-Reviewed Medical Research Program (W81XWH-04-1-0067 to SJS) and by Johns Hopkins University School of Medicine General Clinical Research Center (M01-RR00052 from the National Center for Research Resources, National Institutes of Health). NR 16 TC 4 Z9 4 U1 1 U2 2 PU OXFORD UNIV PRESS INC PI CARY PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA SN 1537-6613 J9 J INFECT DIS JI J. Infect. Dis. PD JUL 1 PY 2011 VL 204 IS 1 BP 60 EP 64 DI 10.1093/infdis/jir220 PG 5 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA 790AV UT WOS:000292561800010 PM 21628659 ER PT J AU Belmont, PJ Thomas, D Goodman, GP Schoenfeld, AJ Zacchilli, M Burks, R Owens, BD AF Belmont, Philip J., Jr. Thomas, Dimitri Goodman, Gens P. Schoenfeld, Andrew J. Zacchilli, Michael Burks, Rob Owens, Brett D. TI Combat Musculoskeletal Wounds in a US Army Brigade Combat Team During Operation Iraqi Freedom SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Article DE Military; Combat; Casualty; Wound; Musculoskeletal; Injury ID IMPROVISED EXPLOSIVE DEVICES; ENDURING FREEDOM; UNITED-STATES; ORTHOPEDIC INJURIES; SURGICAL-TEAM; CASUALTY CARE; EXPERIENCE; TRAUMA; AMPUTATIONS; AFGHANISTAN AB Background: A prospective, longitudinal analysis of musculoskeletal combat injuries sustained by a large combat-deployed maneuver unit has not previously been performed. Methods: A detailed description of the musculoskeletal combat casualty care statistics, distribution of wounds, and mechanisms of injury incurred by a US Army Brigade Combat Team during "The Surge" phase of Operation Iraqi Freedom was performed using a centralized casualty database and an electronic medical record system. Results: Among the 4,122 soldiers deployed, there were 242 musculoskeletal combat wounds in 176 combat casualties. The musculoskeletal combat casualty rate for the Brigade Combat Team was 34.2 per 1,000 soldier combat-years. Spine, pelvis, and long bone fractures comprised 55.9% (33 of 59) of the total fractures sustained in combat. Explosions accounted for 80.7% (142 of 176) of all musculoskeletal combat casualties. Musculoskeletal combat casualty wound incidence rates per 1,000 combat-years were as follows: major amputation, 2.1; minor amputation, 0.6; open fracture, 5.0; closed fracture, 6.4; and soft-tissue/neurovascular injury, 32.8. Among musculoskeletal combat casualties, the likelihood of a gunshot wound causing an open fracture was significantly greater (45.8% [11 of 24]) when compared with explosions (10.6% [15 of 142]) (p = 0.0006). Long bone amputations were more often caused by explosive mechanisms than gunshot wounds. Conclusions: A large burden of complex orthopedic injuries has resulted from the combat experience in Operation Iraqi Freedom. This is because of increased enemy reliance on explosive devices, the use of individual and vehicular body armor, and improved survivability of combat-injured soldiers. C1 [Belmont, Philip J., Jr.] William Beaumont Army Med Ctr, Orthopaed Surg Serv, Dept Orthopaed Surg, El Paso, TX 79920 USA. [Burks, Rob] USN, Postgrad Sch, Grad Sch Operat & Informat Sci, Monterey, CA USA. [Owens, Brett D.] US Mil Acad, Keller Army Community Hosp, Dept Orthopaed Surg, West Point, NY 10996 USA. RP Belmont, PJ (reprint author), William Beaumont Army Med Ctr, Orthopaed Surg Serv, Dept Orthopaed Surg, 5005 N Piedras, El Paso, TX 79920 USA. EM philip.belmont@us.army.mil RI Burks, Robert/J-2481-2015; OI Burks, Robert/0000-0001-6443-6653; Belmont, Philip/0000-0003-2618-199X; Schoenfeld, Andrew/0000-0002-3691-1215 NR 38 TC 22 Z9 22 U1 0 U2 8 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0022-5282 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD JUL PY 2011 VL 71 IS 1 BP E1 EP E7 DI 10.1097/TA.0b013e3181edebed PG 7 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 790RR UT WOS:000292607400001 PM 21045748 ER PT J AU Bailey, JR Stinner, DJ Blackbourne, LH Hsu, JR Mazurek, MT AF Bailey, James R. Stinner, Daniel J. Blackbourne, Lorne H. Hsu, Joseph R. Mazurek, Michael T. TI Combat-Related Pelvis Fractures in Nonsurvivors SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Article; Proceedings Paper CT 6th Research Symposium on Extremity War Injuries (EWI) CY 2011 CL Washington, DC DE Pelvis; Fractures; Combat; Wartime; Associated injuries; Mortality ID MORTALITY; TRAUMA; INJURIES; CLASSIFICATION; MANAGEMENT; OUTCOMES AB Background: The purpose of this study was to describe pelvic fractures and their associated injuries in service members who either died of wounds or were killed in action during Operation Iraqi Freedom and Operation Enduring Freedom and define any differences in associated injuries between penetrating versus blunt injury to the pelvis. Methods: A review of all service members who sustained a pelvis fracture during Operation Iraqi Freedom and Operation Enduring Freedom in the year 2008 was performed. Data were recorded for analysis. Results: One hundred four nonsurvivors were identified with pelvic fractures. Appropriate records, photos, and radiographs were available for 91, 70 were classified as "Not Survivable" (77%) and 21 "Potentially Survivable" (23%). Mechanisms of injury included 69 blast (76%), 14 gunshot wounds (15%), 4 motor vehicle accidents (4.5%), and 4 "other" (4.5%). Direct injury to the pelvis was penetrating in 60 (66%) and blunt in 31 (34%). Large pelvic vessel injury was observed more frequently in penetrating pelvic injuries (27%) than blunt injuries (3%). Hollow viscus abdominal injuries were more common in those with penetrating (57%) than blunt injuries (10%). There was an inverse relationship with intra-abdominal, solid organ injuries (blunt, 81%; penetrating, 55%). Head injuries were also more common in blunt pelvic injuries (blunt, 68%; penetrating, 45%), as were cardiopulmonary injuries (blunt, 84%, penetrating injuries, 57%). Conclusions: Large pelvic vessel and hollow viscus injuries occur more frequently in penetrating combat-related pelvic fractures, whereas intra-abdominal solid organ, head, and cardiopulmonary injuries are more common in blunt pelvic injuries. C1 [Bailey, James R.; Mazurek, Michael T.] USN, Dept Orthopaed Surg, San Diego Med Ctr, San Diego, CA 92134 USA. [Stinner, Daniel J.; Blackbourne, Lorne H.; Hsu, Joseph R.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. RP Bailey, JR (reprint author), USN, Dept Orthopaed Surg, San Diego Med Ctr, 34800 Bob Wilson Dr, San Diego, CA 92134 USA. EM James.Bailey@med.navy.mil OI Stinner, Daniel/0000-0002-8981-6262 NR 25 TC 8 Z9 9 U1 0 U2 1 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0022-5282 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD JUL PY 2011 VL 71 SU 1 BP S58 EP S61 DI 10.1097/TA.0b013e31822154d8 PG 4 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 790RW UT WOS:000292607900010 PM 21795891 ER PT J AU Blackbourne, LH Baer, DG Cestero, RF Inaba, K Rasmussen, TE AF Blackbourne, Lorne H. Baer, David G. Cestero, Ramon F. Inaba, Kenji Rasmussen, Todd E. TI Exsanguination Shock: The Next Frontier in Prevention of Battlefield Mortality SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Editorial Material ID COMBAT CASUALTY CARE; IRREVERSIBLE HEMORRHAGIC-SHOCK; OPERATION-ENDURING-FREEDOM; IMPROVES SURVIVAL; DEATH; INJURY; SYSTEM; DAMAGE; DOGS; WAR C1 [Blackbourne, Lorne H.; Baer, David G.; Rasmussen, Todd E.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Cestero, Ramon F.] USN, Med Res Unit San Antonio, Ft Sam Houston, TX USA. [Inaba, Kenji] Univ So Calif, Div Trauma & Crit Care, Los Angeles, CA USA. [Rasmussen, Todd E.] Uniformed Serv Univ Hlth Sci, F Edward Hebert Sch Med, Norman M Rich Dept Surg, Bethesda, MD 20814 USA. RP Blackbourne, LH (reprint author), USA, Inst Surg Res, 3698 Chambers Pass,BLDG 3611, Ft Sam Houston, TX 78234 USA. EM lorne.h.blackbourne@us.army.mil NR 26 TC 10 Z9 10 U1 0 U2 3 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0022-5282 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD JUL PY 2011 VL 71 SU 1 BP S1 EP S3 DI 10.1097/TA.0b013e3182211286 PG 3 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 790RW UT WOS:000292607900001 PM 21795887 ER PT J AU Hospenthal, DR Crouch, HK English, JF Leach, F Pool, J Conger, NG Whitman, TJ Wortmann, GW Robertson, JL Murray, CK AF Hospenthal, Duane R. Crouch, Helen K. English, Judith F. Leach, Fluryanne Pool, Jane Conger, Nicholas G. Whitman, Timothy J. Wortmann, Glenn W. Robertson, Janelle L. Murray, Clinton K. TI Multidrug-Resistant Bacterial Colonization of Combat-Injured Personnel at Admission to Medical Centers After Evacuation From Afghanistan and Iraq SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Article DE Infection control; Military; Trauma; Acinetobacter; E. coli; Klebsiella ID INFECTION-CONTROL CHALLENGES; US ARMY SOLDIERS; ACINETOBACTER-BAUMANNII; OPERATIONS; CASUALTIES; RECOVERY; OUTBREAK; TRAUMA; TIME AB Background: Multidrug-resistant organism (MDRO) infections, including those secondary to Acinetobacter (ACB) and extended spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae (Escherichia coli and Klebsiella species) have complicated the care of combat-injured personnel during Operations Iraqi Freedom and Enduring Freedom. Data suggest that the source of these bacterial infections includes nosocomial transmission in both deployed hospitals and receiving military medical centers (MEDCENs). Admission screening for MDRO colonization has been established to monitor this problem and effectiveness of responses to it. Methods: Admission colonization screening of injured personnel began in 2003 at the three US-based MEDCENs receiving the majority of combat-injured personnel. This was extended to Landstuhl Regional Medical Center (LRMC; Germany) in 2005. Focused on ACB initially, screening was expanded to include all MDROs in 2009 with a standardized screening strategy at LRMC and US-based MEDCENs for patients evacuated from the combat zone. Results: Eighteen thousand five hundred sixty of 21,272 patients admitted to the 4 MEDCENs in calendar years 2005 to 2009 were screened for MDRO colonization. Average admission ACB colonization rates at the US-based MEDCENs declined during this 5-year period from 21% (2005) to 4% (2009); as did rates at LRMC (7-1%). In the first year of screening for all MDROs, 6% (171 of 2,989) of patients were found colonized at admission, only 29% (50) with ACB. Fifty-seven percent of patients (98) were colonized with ESBL-producing E. coli and 11% (18) with ESBL-producing Klebsiella species. Conclusions: Although colonization with ACB declined during the past 5 years, there seems to be replacement of this pathogen with ESBL-producing Enterobacteriaceae. C1 [Hospenthal, Duane R.] Brooke Army Med Ctr, San Antonio Mil Med Ctr, Infect Dis Serv, MCHE MDI, Ft Sam Houston, TX 78234 USA. [Crouch, Helen K.] Brooke Army Med Ctr, Infect Control Serv, Ft Sam Houston, TX 78234 USA. [Hospenthal, Duane R.; Wortmann, Glenn W.; Robertson, Janelle L.; Murray, Clinton K.] Uniformed Serv Univ Hlth Sci, F Edward Hebert Sch Med, Dept Med, Bethesda, MD 20814 USA. [English, Judith F.] USN, Bur Med & Surg, Washington, DC USA. [Leach, Fluryanne] Walter Reed Army Med Ctr, Infect Control Serv, Washington, DC 20307 USA. [Wortmann, Glenn W.] Walter Reed Army Med Ctr, Infect Dis Serv, Washington, DC 20307 USA. [Conger, Nicholas G.] Landstuhl Reg Med Ctr, Div Infect Dis, Ramstein AFB, Germany. [Pool, Jane] Landstuhl Reg Med Ctr, Infect Control Div, Ramstein AFB, Germany. [Whitman, Timothy J.] Natl Naval Med Ctr, Div Infect Dis, Bethesda, MD USA. RP Hospenthal, DR (reprint author), Brooke Army Med Ctr, San Antonio Mil Med Ctr, Infect Dis Serv, MCHE MDI, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA. EM duane.hospenthal@amedd.army.mil NR 25 TC 30 Z9 31 U1 0 U2 7 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0022-5282 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD JUL PY 2011 VL 71 SU 1 BP S52 EP S57 DI 10.1097/TA.0b013e31822118fb PG 6 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 790RW UT WOS:000292607900009 PM 21795879 ER PT J AU Kheirabadi, BS Arnaud, F McCarron, R Murdock, AD Hodge, DL Ritter, B Dubick, MA Blackbourne, LH AF Kheirabadi, Bijan S. Arnaud, Francoise McCarron, Richard Murdock, Alan D. Hodge, Douglas L. Ritter, Brandi Dubick, Michael A. Blackbourne, Lorne H. TI Development of a Standard Swine Hemorrhage Model for Efficacy Assessment of Topical Hemostatic Agents SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Article DE Hemorrhage model; Hemostatic agent; Combat gauze; Efficacy; Swine ID EXTREMITY ARTERIAL HEMORRHAGES; CLOT-INDUCING MINERALS; SMECTITE GRANULES; GROIN INJURY; LETHAL MODEL; DRESSINGS; COAGULOPATHY; SURVIVAL; GAUZE AB Background: The diverse information of efficacy of hemostatic products, obtained from different military laboratories using different models, has made it difficult to ascertain the true benefit of new hemostatic agents in military medicine. The aim of this study was to recommend a standard hemorrhage model for efficacy testing acceptable by most investigators in the field and avoid contradictory and duplicative efforts by different laboratories. Methods: The swine femoral artery injury model (6-mm arteriotomy) with some modifications was tested to standardize the model. The suggested modifications included no splenectomy, one-time treatment, 30 seconds free bleeding, and 5 L limit for fluid resuscitation. The model was tested with all or some of these modifications in four experimental conditions (n = 5-6 pigs per condition) using Combat Gauze (CG) as control agent. Results: The primary end points including blood pressure, blood loss, and survival rates were modestly changed in the four conditions. The second experimental condition in which bleeding was treated with a single CG with 3-minute compression produced the most suitable results. The average blood loss was 99 mL/kg, and hemostasis was achieved in one-third of the pigs, which led to matching survival rate. Conclusion: A rigorous hemorrhage model was developed for future evaluation of new hemostatic agents and comparison with CG, the current standard of care. This model may not be suitable for testing every agent and some modifications may be necessary for specific applications. Furthermore, laboratory studies using this or similar models must be accompanied by operational testing in the field to confirm the efficacy and practical utility of selected agents when used on the battlefield. C1 [Kheirabadi, Bijan S.; Dubick, Michael A.; Blackbourne, Lorne H.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Arnaud, Francoise; McCarron, Richard] USN, Neuro Trauma Dept, Med Res Ctr, Silver Spring, MD USA. [Murdock, Alan D.] USAF, Med Operat Agcy, Lackland AFB, TX USA. [Hodge, Douglas L.; Ritter, Brandi] Def Med Standardizat Board, Ft Detrick, MD USA. RP Kheirabadi, BS (reprint author), 3400 Rawley E Chambers Ave,Bldg 3611, Ft Sam Houston, TX 78234 USA. EM bijan.kheirabadi@us.army.mil FU US Army Medical Research and Materiel Command FX Authors of this article are military service members or employees of the US Government. The funding for this work was provided solely by the US Army Medical Research and Materiel Command. NR 17 TC 16 Z9 17 U1 0 U2 9 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0022-5282 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD JUL PY 2011 VL 71 SU 1 BP S139 EP S146 DI 10.1097/TA.0b013e318221931e PG 8 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 790RW UT WOS:000292607900024 PM 21795871 ER PT J AU Simecek, JW Schultz, ST Anderson, WH Gunning, RL AF Simecek, John W. Schultz, Stephen T. Anderson, William H., III Gunning, Rodney L. TI The Severity of Oral/Facial Problems Treated in Iraq March 2008 to February 2009 SO JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE LA English DT Article DE Dental emergency; Epidemiology; Risk assessment; Military ID DENTAL EMERGENCY RATES; PERSONNEL; FREEDOM; BOSNIA AB Background: The objective of this study was to describe the severity of oral/facial problems occurring in Navy and Marine Corps personnel deployed to Iraq. Methods: Data documented by Navy Dental Officers deployed to Iraq were used to determine the number and type of oral/facial problems treated and to determine the percentages of severe, moderately severe, and pain/loss of function oral/facial problems treated in Iraq from March 2008 through February 2009. Results: During the year of data collection, a total of 13,933 dental visits were documented for Navy and Marine Corps personnel. Of these, 1,641 were encounters to treat an oral/facial problem in Navy and Marine Corps personnel. In all, 37 (2.2%) of the 1,641 encounters for oral/facial problems were considered severe, 266 (16.2%) moderately severe, and 1,338 (81.5%) were for pain/loss of function. Conclusions: Although the majority of military personnel with oral/facial problems experience mild to moderate pain or loss of dental function, approximately 20% are of sufficient severity to cause the warfighter to experience a limitation of their operational capability. C1 [Simecek, John W.; Schultz, Stephen T.; Anderson, William H., III] USN, Med Res Unit San Antonio, Ft Sam Houston, TX USA. [Gunning, Rodney L.] Second Dent Battal Naval Dent Clin, Camp Lejeune, NC USA. RP Simecek, JW (reprint author), 3650 Chambers Pass, Ft Sam Houston, TX 78234 USA. EM john.simecek@amedd.army.mil FU Bureau of Medicine and Surgery FX Funding provided by the Bureau of Medicine and Surgery. NR 19 TC 1 Z9 1 U1 0 U2 0 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0022-5282 J9 J TRAUMA JI J. Trauma-Injury Infect. Crit. Care PD JUL PY 2011 VL 71 SU 1 BP S43 EP S46 DI 10.1097/TA.0b013e3182211497 PG 4 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 790RW UT WOS:000292607900007 PM 21795877 ER PT J AU Sharp, TW AF Sharp, Trueman W. TI Untitled SO MILITARY MEDICINE LA English DT Letter C1 USN, Stennis Space Ctr, MS 39529 USA. RP Sharp, TW (reprint author), USN, Stennis Space Ctr, MS 39529 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ASSOC MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA SN 0026-4075 J9 MIL MED JI Milit. Med. PD JUL PY 2011 VL 176 IS 7 SU S BP VI EP VI PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA 792XQ UT WOS:000292784100004 ER PT J AU Smith, TC AF Smith, Tyler C. CA Millennium Cohort Study Team TI Linking Exposures and Health Outcomes to a Large Population-Based Longitudinal Study: The Millennium Cohort Study SO MILITARY MEDICINE LA English DT Article ID GULF-WAR VETERANS; DEPARTMENT-OF-DEFENSE; POSTTRAUMATIC-STRESS-DISORDER; MILITARY SERVICE MEMBERS; SELF-REPORTED SYMPTOMS; US MILITARY; COMBAT DEPLOYMENT; FUNCTIONAL HEALTH; MENTAL-DISORDERS; ANTHRAX VACCINE AB Objective: To describe current efforts and future potential for understanding long-term health of military service members by linking the Millennium Cohort Study data to exposures and health outcomes. Methods: The Millennium Cohort Study launched in 2001, before September 11 and the start of combat operations in Afghanistan and Iraq. Other substantial Department of Defense (DoD) health, personnel, and exposure databases are maintained in electronic form and may be linked by personal identifiers. Results: More than 150,000 consenting members comprise the Millennium Cohort from all services, and include active duty, Reserve, and National Guard current and past members, and represent demographic, occupational, military, and health characteristics of the U.S. military. These prospective data offer symptom assessment, behavioral health, and self-reported exposures that may complement and fill gaps in capability presented by other DoD electronic health and exposure data. Conclusions: In conjunction with Millennium Cohort survey data, prospective individual-level exposure and health outcome assessment is crucial to understand and quantify any long-term health outcomes potentially associated with unique military occupational exposures. C1 [Smith, Tyler C.; Millennium Cohort Study Team] Naval Hlth Res Ctr, Dept Deployment Hlth Res, San Diego, CA 92106 USA. RP Smith, TC (reprint author), Naval Hlth Res Ctr, Dept Deployment Hlth Res, 140 Sylvester Rd, San Diego, CA 92106 USA. FU Department of Defense FX This work represents report 10-37, supported by the Department of Defense, under work unit no. 60002. The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the Navy, Department of the Army, Department of the Air Force, Department of Defense, Department of Veterans Affairs, or the U.S. Government. This research has been conducted in compliance with all applicable federal regulations governing the protection of human subjects in research (Protocol NHRC.2000.0007). NR 75 TC 5 Z9 6 U1 2 U2 11 PU ASSOC MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA SN 0026-4075 J9 MIL MED JI Milit. Med. PD JUL PY 2011 VL 176 IS 7 SU S BP 56 EP 63 PG 8 WC Medicine, General & Internal SC General & Internal Medicine GA 792XQ UT WOS:000292784100015 PM 21916332 ER PT J AU Gunepin, M Derache, F Ausset, I Berlizot, P Simecek, J AF Gunepin, Mathieu Derache, Florence Ausset, Isabelle Berlizot, Patrick Simecek, John TI The Rate of Dental Emergencies in French Armed Forces Deployed to Afghanistan SO MILITARY MEDICINE LA English DT Article ID OVERSEAS DEPLOYMENTS; DISEASES; FREEDOM; HEALTH; IMPACT AB Objectives: The objectives of this study were as follows: (1) to quantify the dental emergency (DE) rate observed in French soldiers serving in Afghanistan and (2) to determine the percentage of DEs that could have been prevented had predeployment treatment been provided. Methods: All DEs presenting at the French medical surgical hospital in Kabul, Afghanistan, were documented during the period of December 12, 2009 to February 6, 2010. Dental Officers documented (1) the etiology of each DE and (2) whether the DE could have been prevented with predeployment treatment. Results: An estimated rate of 293 DE per 1,000 personnel per year was observed, 78% of the 210 DEs were considered preventable, and 65% of patients required medical evacuation from their units. Conclusion: Previous studies have observed high DE rates for French Army personnel. The intensity, danger, and geography of the mission in Afghanistan exacerbate the negative operational impact of dental pathologies. C1 [Gunepin, Mathieu] Mil Sch Artillery, F-83007 Draguignan, France. [Derache, Florence] Mil Hosp St Anne, F-83041 Toulon 9, France. [Ausset, Isabelle] Mil Hosp Begin, F-94163 St Mande, France. [Berlizot, Patrick] Mil Hosp Val de Grace, F-75230 Paris 5, France. [Simecek, John] USN, Med Res Unit San Antonio, Ft Sam Houston, TX 78234 USA. RP Gunepin, M (reprint author), Mil Sch Artillery, BP 400, F-83007 Draguignan, France. FU Work Unit [G1004] FX Dr. Simecek's portion of this work was supported by Work Unit G1004. NR 21 TC 5 Z9 8 U1 0 U2 1 PU ASSOC MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA SN 0026-4075 J9 MIL MED JI Milit. Med. PD JUL PY 2011 VL 176 IS 7 BP 828 EP 832 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA 792XO UT WOS:000292783900016 PM 22128727 ER PT J AU Phillips, JB Simmons, RG Arnold, RD AF Phillips, Jeffrey B. Simmons, Rita G. Arnold, Richard D. TI A Single Dose of Armodafinil Significantly Promotes Vigilance 11 Hours Post-Dose SO MILITARY MEDICINE LA English DT Article ID SLEEP-DEPRIVATION; HEALTHY-SUBJECTS; PERFORMANCE; ALERTNESS; MODAFINIL; SAFETY AB Objective: This study was conducted to test the ability of armodafinil to promote vigilance among air traffic control operators 8 to 11 hours post-dose. Methods: Forty-eight U.S. Naval air traffic control students were assigned to one of two groups, 150 mg dose of armodafinil or placebo. At 8:00 a.m., participants were administered armodafinil or a placebo, after which they completed a standard work day. Participants returned at 3:45 p.m. to complete the 4-hour performance portion of the study, where they performed the psychomotor vigilance task. Results: The analysis showed a significant difference in vigilance between the armodafinil group and placebo (p < 0.05). Psychomotor vigilance task data revealed that participants receiving a 150 mg dose of armodafinil experienced significantly fewer lapses of attention compared to the control group. Conclusions: These results justify additional investigation into the efficacy of armodafinil to promote sustained vigilance in military operational settings where fatigue-related performance decrements are especially problematic. C1 [Phillips, Jeffrey B.; Simmons, Rita G.; Arnold, Richard D.] USN, Aerosp Med Res Lab, Pensacola, FL 32508 USA. RP Phillips, JB (reprint author), USN, Aerosp Med Res Lab, 280 Fred Bauer St,Bldg 1811, Pensacola, FL 32508 USA. FU Cephalon; [70707] FX The project was funded by Cephalon and supported through work unit number 70707. In the interest of full disclosure, it must be noted that Cephalon is the manufacturer of the drug mentioned in this manuscript. However. Cephelon had no influence on the results of the research. NR 26 TC 1 Z9 2 U1 0 U2 4 PU ASSOC MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA SN 0026-4075 J9 MIL MED JI Milit. Med. PD JUL PY 2011 VL 176 IS 7 BP 833 EP 839 PG 7 WC Medicine, General & Internal SC General & Internal Medicine GA 792XO UT WOS:000292783900017 PM 22128728 ER PT J AU Reynolds, CA McLay, JG Goerss, JS Serra, EA Hodyss, D Sampson, CR AF Reynolds, Carolyn A. McLay, Justin G. Goerss, James S. Serra, Efren A. Hodyss, Daniel Sampson, Charles R. TI Impact of Resolution and Design on the US Navy Global Ensemble Performance in the Tropics SO MONTHLY WEATHER REVIEW LA English DT Article ID ANALYSIS-PERTURBATION SCHEME; PREDICTION SYSTEM; STOCHASTIC CONVECTION; TRANSFORM; MODEL; NCEP; PARAMETERIZATIONS; FORMULATION; GENERATION; FORECASTS AB The performance of the U.S. Navy global atmospheric ensemble prediction system is examined with a focus on tropical winds and tropical cyclone tracks. Ensembles are run at a triangular truncation of T119, T159, and T239, with 33, 17, and 9 ensemble members, respectively, to evaluate the impact of resolution versus the number of ensemble member tradeoffs on ensemble performance. Results indicate that the T159 and T239 ensemble mean tropical cyclone track errors are significantly smaller than those of the T119 ensemble out to 4 days. For ensemble forecasts of upper- and lower-tropospheric tropical winds, increasing resolution has only a small impact on ensemble mean root-mean-square error for wind speed, but does improve Brier scores for 10-m wind speed at the 5 m s(-1) threshold. In addition to the resolution tests, modifications to the ensemble transform initial perturbation methodology and inclusion of stochastic kinetic energy backscatter are also evaluated. Stochastic kinetic energy backscatter substantially increases the ensemble spread and improves Brier scores in the tropics, but for the most part does not significantly reduce ensemble mean tropical cyclone track error. C1 [Reynolds, Carolyn A.; McLay, Justin G.; Goerss, James S.; Hodyss, Daniel; Sampson, Charles R.] USN, Res Lab, Monterey, CA 93943 USA. [Serra, Efren A.] DeVine Consulting Inc, Fremont, CA USA. RP Reynolds, CA (reprint author), USN, Res Lab, 7 Grace Hopper Ave, Monterey, CA 93943 USA. EM carolyn.reynolds@nrlmry.navy.mil OI Reynolds, Carolyn/0000-0003-4690-4171 FU NOAA; Office of Naval Research (ONR) [0602435N, 0601153N] FX We gratefully acknowledge the support of the NOAA Hurricane Forecast Improvement Project and the Office of Naval Research (ONR) through Program Element 0602435N and 0601153N. The DoD High Performance Computing Program at NAVO MSRC provided part of the computing resources. NR 35 TC 14 Z9 14 U1 0 U2 2 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 USA SN 0027-0644 J9 MON WEATHER REV JI Mon. Weather Rev. PD JUL PY 2011 VL 139 IS 7 BP 2145 EP 2155 DI 10.1175/2011MWR3546.1 PG 11 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA 792EJ UT WOS:000292723000007 ER PT J AU Hughes, CL Marshall, R Murphy, E Mun, SK AF Hughes, Cortney L. Marshall, Robert Murphy, Edward Mun, Seong K. TI Technologies in the Patient-Centered Medical Home: Examining the Model from an Enterprise Perspective SO TELEMEDICINE AND E-HEALTH LA English DT Article DE technology; policy; medical records; telemedicine; business administration/economics AB Fee-for-service reimbursement has fragmented the healthcare system. Providers are paid based on the number of services rendered instead of quality, leading to the cost of care rising at a faster rate than its value. One approach to counter this is the Patient-Centered Medical Home (PCMH), a primary care model that emphasizes team-based medicine, a partnership between patients and providers, and expanded access and communication. The transition to PCMH is facilitated by innovative technologies, such as telemedicine for additional services, electronic medical records to document patients' health needs, and online portals for electronic visits and communication between patients and providers. Implementing these technologies involves tremendous investment of funds and time from practices and healthcare organizations. Although PCMH does not require such technologies, they facilitate its success, as care coordination and population management necessitated by the model are difficult to do without. This article argues that there is a paradox in PCMH and technology is at its center. Although PCMH intends to be cost effective by reducing hospital admissions and ER visits through providing better preventative services, it is actually a financial risk due to the very real upfront costs of implementing and sustaining technologies needed to carry out the intent of the PCMH model, which may not be made up immediately, if ever. This article delves into the rationale behind why payers, providers, and patients have adopted PCMH regardless of this risk and in doing so, maps out the roles that innovative technologies play in the conversion to PCMH. C1 [Hughes, Cortney L.; Mun, Seong K.] Virginia Tech, Arlington Innovat Ctr Hlth Res, Arlington, VA 22314 USA. [Marshall, Robert] USN, Bur Med & Surg, Washington, DC USA. [Murphy, Edward] Carilion Clin, Roanoke, VA USA. RP Hughes, CL (reprint author), Virginia Tech, Arlington Innovat Ctr Hlth Res, 1101 King St,Suite 610, Arlington, VA 22314 USA. EM clhughes@vt.edu FU HighView CRADA, TATRC, USAMRMC [W81XWH-08-2-0173] FX The authors would like to thank Jennifer LeFurgy for her leadership in designing the PCMH Workshop held at the George Washington Memorial in Alexandria, VA on June 30, 2010. The authors would also like to thank all the participants for their presentations and especially Phyllis Torda, Dr. Paul Grundy, John Wendland, M. Colette Carver, Dr. Howard Graman, and MAJ Michelle Miner for their comments at the workshop, which made this article possible. This work is in part supported by HighView CRADA, W81XWH-08-2-0173, TATRC, USAMRMC. NR 36 TC 3 Z9 3 U1 0 U2 6 PU MARY ANN LIEBERT INC PI NEW ROCHELLE PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA SN 1530-5627 J9 TELEMED E-HEALTH JI Telemed. e-Health PD JUL-AUG PY 2011 VL 17 IS 6 BP 495 EP 500 DI 10.1089/tmj.2010.0218 PG 6 WC Health Care Sciences & Services SC Health Care Sciences & Services GA 794CD UT WOS:000292872100017 PM 21663447 ER PT J AU Schwenk, RJ Richie, TL AF Schwenk, Robert J. Richie, Thomas L. TI Protective immunity to pre-erythrocytic stage malaria SO TRENDS IN PARASITOLOGY LA English DT Review ID T-CELL RESPONSES; PLASMODIUM-FALCIPARUM SPOROZOITES; YELLOW-FEVER VACCINE; LIVER STAGES; CIRCUMSPOROZOITE PROTEIN; IRRADIATED SPOROZOITES; IN-VIVO; PROTRACTED PROTECTION; MEDIATED PROTECTION; STERILE PROTECTION AB The development of a vaccine against malaria is a major research priority given the burden of disease, death and economic loss inflicted upon the tropical world by this parasite. Despite decades of effort, however, a vaccine remains elusive. The best candidate is a subunit vaccine termed RTS,S but this provides only partial protection against clinical disease. This review examines what is known about protective immunity against pre-erythrocytic stage malaria by considering the humoral and T cell-mediated immune responses that are induced by attenuated sporozoites and by the RTS,S vaccine. On the basis of these observations a set of research priorities are defined that are crucial for the development of a vaccine capable of inducing long-lasting and high-grade protection against malaria. C1 [Schwenk, Robert J.] Walter Reed Army Inst Res, Div Malaria Vaccine Dev, Silver Spring, MD 20910 USA. [Richie, Thomas L.] USN, Med Res Ctr, Infect Dis Directorate, Silver Spring, MD 20910 USA. EM robert.schwenk@amedd.army.mil OI Richie, Thomas/0000-0002-2946-5456 NR 78 TC 19 Z9 19 U1 0 U2 5 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 1471-4922 J9 TRENDS PARASITOL JI Trends Parasitol. PD JUL PY 2011 VL 27 IS 7 BP 306 EP 314 DI 10.1016/j.pt.2011.02.002 PG 9 WC Parasitology SC Parasitology GA 791PD UT WOS:000292676200006 PM 21435951 ER PT J AU Biffinger, JC Uppaluri, S Sun, HR DiMagno, SG AF Biffinger, Justin C. Uppaluri, ShriHarsha Sun, Haoran DiMagno, Stephen G. TI Ligand Fluorination to Optimize Preferential Oxidation of Carbon Monoxide by Water-Soluble Rhodium Porphyrins SO ACS CATALYSIS LA English DT Article DE rhodium; fluorinated macrocycle; porphyrin; carbon monoxide; oxidation; fuel cells ID GAS SHIFT CATALYSTS; FUEL-CELL; ELECTROCHEMICAL GENERATION; METAL-CATALYSTS; CO ATMOSPHERE; HYDROGEN; EQUILIBRIUM; H-2; ELECTROOXIDATION; HYDROCARBONS AB Catalytic, low temperature preferential oxidation (PROX) of carbon monoxide by aqueous [5,10,15,20-tetrakis-(4-sulfonatopheny)-2,3,7,8,12,13,17,18-octafluoroporphyrinato]-rhodium(III) tetrasodium salt, (1[Rh(III)]) and [5,10,15, 20-tetrakis(3-sulfonato-2,6-difluorophenyl)-2,3,7,8,12,13,17,18-octafluoroporphyrinato]rhodium(III) tetrasodium salt, (2[Rh(III)]) is reported. The PROX reaction occurs at ambient temperature in buffered (4 <= pH <= 13) aqueous solutions. Fluorination on the porphyrin periphery is shown to increase the CO PROX reaction rate, shift the metal centered redox potentials, and acidify ligated water molecules. Most importantly, beta-fluorination increases the acidity of the rhodium hydride complex (pK(a) = 2.2 +/- 0.2 for 2[Rh-D]); the dramatically increased acidity of the Rh(III) hydride complex precludes proton reduction and hydrogen activation near neutral pH, thereby permitting oxidation of CO to be unaffected by the presence of H(2). This new fluorinated water-soluble rhodium porphyrin-based homogeneous catalyst system permits preferential oxidation of Carbon monoxide in hydrogen gas streams at 308 K using dioxygen or a sacrificial electron acceptor (indigo carmine) as the terminal oxidant. C1 [Biffinger, Justin C.; Uppaluri, ShriHarsha; Sun, Haoran; DiMagno, Stephen G.] Univ Nebraska, Dept Chem, Lincoln, NE 68588 USA. [Biffinger, Justin C.; Uppaluri, ShriHarsha; Sun, Haoran; DiMagno, Stephen G.] Univ Nebraska, Nebraska Ctr Mat & Nanosci, Lincoln, NE 68588 USA. [Biffinger, Justin C.] USN, Res Lab, Div Chem, Washington, DC 20375 USA. [Sun, Haoran] Univ S Dakota, Vermillion, SD 57069 USA. RP DiMagno, SG (reprint author), Univ Nebraska, Dept Chem, Lincoln, NE 68588 USA. EM sdimagno1@unl.edu RI DiMagno, Stephen/H-9459-2016 OI DiMagno, Stephen/0000-0001-7861-4799 FU ONR; DARPA [N66001-08-1-2026] FX The work was supported through the ONR and DARPA (N66001-08-1-2026) for support of the research and the National Institutes of Health (RR016544-01) for laboratory infrastructure. NR 53 TC 11 Z9 11 U1 3 U2 31 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 2155-5435 J9 ACS CATAL JI ACS Catal. PD JUL PY 2011 VL 1 IS 7 SI SI BP 764 EP 771 DI 10.1021/cs2001187 PG 8 WC Chemistry, Physical SC Chemistry GA 788YD UT WOS:000292479400013 PM 21949596 ER PT J AU Lee, ZP Du, KP Voss, KJ Zibordi, G Lubac, B Arnone, R Weidemann, A AF Lee, Zhong Ping Du, Keping Voss, Kenneth J. Zibordi, Giuseppe Lubac, Bertrand Arnone, Robert Weidemann, Alan TI An inherent-optical-property-centered approach to correct the angular effects in water-leaving radiance SO APPLIED OPTICS LA English DT Article ID REMOTE-SENSING REFLECTANCE; DIFFUSE ATTENUATION COEFFICIENT; VOLUME SCATTERING FUNCTION; OCEAN COLOR IMAGERY; BIDIRECTIONAL REFLECTANCE; THEORETICAL DERIVATION; ATMOSPHERIC CORRECTION; SENSED REFLECTANCE; RAMAN-SCATTERING; PHASE FUNCTION AB Remote-sensing reflectance (R-rs), which is defined as the ratio of water-leaving radiance (L-w) to down-welling irradiance just above the surface (E-d(0(+))), varies with both water constituents (including bottom properties of optically-shallow waters) and angular geometry. L-w is commonly measured in the field or by satellite sensors at convenient angles, while E-d(0(+)) can be measured in the field or estimated based on atmospheric properties. To isolate the variations of R-rs (or L-w) resulting from a change of water constituents, the angular effects of R-rs (or L-w) need to be removed. This is also a necessity for the calibration and validation of satellite ocean color measurements. To reach this objective, for optically-deep waters where bottom contribution is negligible, we present a system centered on water's inherent optical properties (IOPs). It can be used to derive IOPs from angular R-rs and offers an alternative to the system centered on the concentration of chlorophyll. This system is applicable to oceanic and coastal waters as well as to multiband and hyperspectral sensors. This IOP-centered system is applied to both numerically simulated data and in situ measurements to test and evaluate its performance. The good results obtained suggest that the system can be applied to angular R-rs to retrieve IOPs and to remove the angular variation of R-rs. (C) 2011 Optical Society of America C1 [Lee, Zhong Ping] Mississippi State Univ, Geosyst Res Inst, Stennis Space Ctr, MS 39529 USA. [Du, Keping] Beijing Normal Univ, State Key Lab Remote Sensing Sci, Res Ctr Remote Sensing & GIS, Sch Geog, Beijing 100875, Peoples R China. [Voss, Kenneth J.] Univ Miami, Dept Phys, Coral Gables, FL 33124 USA. [Zibordi, Giuseppe] Joint Res Ctr, Global Environm Monitoring Unit, I-21027 Ispra, Italy. [Lubac, Bertrand] Univ Bordeaux 1, CNRS, UMR EPOC 5805, F-33405 Talence, France. [Arnone, Robert; Weidemann, Alan] USN, Res Lab, Stennis Space Ctr, MS 39529 USA. RP Lee, ZP (reprint author), Mississippi State Univ, Geosyst Res Inst, Stennis Space Ctr, MS 39529 USA. EM zplee@ngi.msstate.edu RI Voss, Kenneth /A-5328-2013 OI Voss, Kenneth /0000-0002-7860-5080 FU Naval Research Laboratory; National Aeronautics and Space Administration (NASA) Ocean Biology and Biogeochemistry; Water and Energy Cycle Programs; Korea Ocean Research and Development Institute; National Key Basic Research Program of China (973 Program) [2007CB714407]; CNRS; Institut National des Sciences de l'Univers; Centre National d'Etudes Spatiales; European Space Agency; NASA; Institut francais de recherche pour l'exploitation de la mer FX Financial support from the Naval Research Laboratory (Lee, Arnone, Weidemann), the National Aeronautics and Space Administration (NASA) Ocean Biology and Biogeochemistry (Lee, Voss) and the Water and Energy Cycle (Lee) Programs, the Korea Ocean Research and Development Institute (Lee), and the National Key Basic Research Program of China (973 Program, grant 2007CB714407, Du) are greatly appreciated. The authors also wish to thank the NASA AERONET team for the continuous effort in processing and quality assuring AERONETOC data. The AOPEX cruise is part of the BOUSSOLE project, which is funded by the CNRS, the Institut National des Sciences de l'Univers, the Centre National d'Etudes Spatiales, the European Space Agency, and the NASA through a Letter of Agreement with the Universite Pierre et Marie Curie. Shiptime on the Suroit R/V was funded by the Institut francais de recherche pour l'exploitation de la mer. We are grateful for the comments and suggestions from two anonymous reviewers. NR 65 TC 34 Z9 34 U1 3 U2 22 PU OPTICAL SOC AMER PI WASHINGTON PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA SN 1559-128X EI 2155-3165 J9 APPL OPTICS JI Appl. Optics PD JUL 1 PY 2011 VL 50 IS 19 BP 3155 EP 3167 DI 10.1364/AO.50.003155 PG 13 WC Optics SC Optics GA 789UU UT WOS:000292542800012 PM 21743515 ER PT J AU Brenneman, KE Doganay, M Akmal, A Goldman, S Galloway, DR Mateczun, AJ Cross, AS Baillie, LW AF Brenneman, Karen E. Doganay, Mehmet Akmal, Arya Goldman, Stanley Galloway, Darrell R. Mateczun, Alfred J. Cross, Alan S. Baillie, Leslie W. TI The early humoral immune response to Bacillus anthracis toxins in patients infected with cutaneous anthrax SO FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY LA English DT Article DE anthrax; lethal factor; edema factor; protective antigen ID LETHAL FACTOR; PROTECTIVE ANTIGEN; INHALATION ANTHRAX; TNF-ALPHA; VACCINE; MACROPHAGES; ANTIBODIES; SPORES; MICE; IMMUNIZATION AB Bacillus anthracis, the causative agent of anthrax, produces a tripartite toxin composed of two enzymatically active subunits, lethal factor (LF) and edema factor (EF), which, when associated with a cell-binding component, protective antigen (PA), form lethal toxin and edema toxin, respectively. In this preliminary study, we characterized the toxin-specific antibody responses observed in 17 individuals infected with cutaneous anthrax. The majority of the toxin-specific antibody responses observed following infection were directed against LE, with immunoglobulin G (IgG) detected as early as 4 days after the onset of symptoms in contrast to the later and lower EF- and PA-specific IgG responses. Unlike the case with infection, the predominant toxin-specific antibody response of those immunized with the US anthrax vaccine absorbed and UK anthrax vaccine precipitated licensed anthrax vaccines was directed against PA. We observed that the LF-specific human antibodies were, like anti-PA antibodies, able to neutralize toxin activity, suggesting the possibility that they may contribute to protection. We conclude that an antibody response to LF might be a more sensitive diagnostic marker of anthrax than to PA. The ability of human LF-specific antibodies to neutralize toxin activity supports the possible inclusion of LF in future anthrax vaccines. C1 [Cross, Alan S.] Univ Maryland, Sch Med, Ctr Vaccine Dev, Dept Med, Baltimore, MD 21201 USA. [Brenneman, Karen E.; Akmal, Arya; Goldman, Stanley; Galloway, Darrell R.; Mateczun, Alfred J.] USN, Biol Def Res Directorate, Med Res Ctr, Rockville, MD USA. [Brenneman, Karen E.; Galloway, Darrell R.] Ohio State Univ, Dept Microbiol, Columbus, OH 43210 USA. [Doganay, Mehmet] Erciyes Univ, Dept Infect Dis, Fac Med, Kayseri, Turkey. [Baillie, Leslie W.] Univ Maryland, Ctr Med Biotechnol, Inst Biotechnol, Baltimore, MD 21201 USA. RP Cross, AS (reprint author), Univ Maryland, Sch Med, Ctr Vaccine Dev, Dept Med, 685 W Baltimore St, Baltimore, MD 21201 USA. EM across@medicine.umaryland.edu OI Baillie, Les/0000-0002-8186-223X FU Defense Threat Reduction Agency [80000.000.000.A0031]; NIH [U54 AI057168-01] FX We thank and acknowledge Dr Emine Alp for her assistance. For their assistance in providing samples and information, we acknowledge Dr Basak Dokuzoguz at Ankara Numune Clinical Research and Education Hospital (Ankara), Dr Mehmet Parlak at Ataturk University (Erzurum), Dr Ayhan Akbulut at Firat University (Elazig) and Dr Ilyas Dokmetas at Cumhuriyet University (Sivas). We also acknowledge Stephanie Gray for her administrative efforts. Finally, we thank all the volunteers for their cooperation in donating their time and blood samples to this study. This work was supported by the Defense Threat Reduction Agency under the work unit number 80000.000.000.A0031 and NIH U54 AI057168-01. All authors have no conflicts. NR 41 TC 11 Z9 12 U1 0 U2 4 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 0928-8244 J9 FEMS IMMUNOL MED MIC JI FEMS Immunol. Med. Microbiol. PD JUL PY 2011 VL 62 IS 2 BP 164 EP 172 DI 10.1111/j.1574-695X.2011.00800.x PG 9 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA 788JA UT WOS:000292440000005 PM 21401726 ER PT J AU Wise, SR Harsha, WJ Kim, N Hayden, RE AF Wise, Sean R. Harsha, Wayne J. Kim, Namou Hayden, Richard E. TI FREE FLAP SURVIVAL DESPITE EARLY LOSS OF THE VASCULAR PEDICLE SO HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK LA English DT Article DE free flap; vascular pedicle; survival; neovascularization; radiotherapy ID MICROVASCULAR FREE FLAPS; NECK RECONSTRUCTION; MUSCULOCUTANEOUS FLAPS; RADIATION-THERAPY; HEAD; NEOVASCULARIZATION; COMPLICATIONS; RADIOTHERAPY; MUSCLE AB Background. Early success of microvascular free tissue transfer is dependent upon the patency of the primary vascular pedicle. In time, neovascularization from the recipient bed and surrounding wound margins into the graft may be sufficient to maintain flap viability. The time necessary for successful neovascularization to occur is unclear. Most believe that prior radiation therapy will delay this process. Methods. This case report describes a patient, status post-chemoradiotherapy, who underwent composite resection with anterolateral thigh free flap reconstruction for a new base of tongue squamous cell carcinoma. On postoperative day 9 the vascular pedicle thrombosed secondary to abscess formation. Results. Despite early loss of the arterial and venous pedicle, the flap survived completely. Conclusion. After microvascular free tissue transfer, neovascularization sufficient to maintain flap viability independent of the primary vascular pedicle may occur by postoperative day 9. This early revascularization can also occur despite a history of radiotherapy. (C) 2010 Wiley Periodicals, Inc.(1) Head Neck 33: 1068-1071, 2011 C1 [Harsha, Wayne J.] Madigan Army Med Ctr, Otolaryngol Serv, Tacoma, WA 98431 USA. [Wise, Sean R.] USN, San Diego Med Ctr, Dept Otolaryngol, San Diego, CA 92152 USA. [Harsha, Wayne J.; Kim, Namou; Hayden, Richard E.] Mayo Clin Arizona, Dept Otolaryngol, Phoenix, AZ USA. [Wise, Sean R.] US Naval Hosp, Dept Otolaryngol Head & Neck Surg, Yokosuka, Kanagawa, Japan. [Kim, Namou] Swedish Canc Inst, Swedish Head & Neck Surg Clin, Seattle, WA USA. RP Harsha, WJ (reprint author), Madigan Army Med Ctr, Otolaryngol Serv, Tacoma, WA 98431 USA. EM wayne.harsha@us.army.mil NR 26 TC 8 Z9 8 U1 0 U2 1 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1043-3074 J9 HEAD NECK-J SCI SPEC JI Head Neck-J. Sci. Spec. Head Neck PD JUL PY 2011 VL 33 IS 7 BP 1068 EP 1071 DI 10.1002/hed.21354 PG 4 WC Otorhinolaryngology; Surgery SC Otorhinolaryngology; Surgery GA 789WL UT WOS:000292549100020 PM 20175197 ER PT J AU Fish, FE Weber, PW Murray, MM Howle, LE AF Fish, Frank E. Weber, Paul W. Murray, Mark M. Howle, Laurens E. TI The Tubercles on Humpback Whales' Flippers: Application of Bio-Inspired Technology SO INTEGRATIVE AND COMPARATIVE BIOLOGY LA English DT Article ID LEADING-EDGE TUBERCLES; MEGAPTERA-NOVAEANGLIAE; HYDRODYNAMIC PERFORMANCE; BALEEN WHALES; REDUCTION; DRAG; PROTUBERANCES; AERODYNAMICS; MECHANISMS; MORPHOLOGY AB The humpback whale (Megaptera novaeangliae) is exceptional among the large baleen whales in its ability to undertake aquabatic maneuvers to catch prey. Humpback whales utilize extremely mobile, wing-like flippers for banking and turning. Large rounded tubercles along the leading edge of the flipper are morphological structures that are unique in nature. The tubercles on the leading edge act as passive-flow control devices that improve performance and maneuver-ability of the flipper. Experimental analysis of finite wing models has demonstrated that the presence of tubercles produces a delay in the angle of attack until stall, thereby increasing maximum lift and decreasing drag. Possible fluid-dynamic mechanisms for improved performance include delay of stall through generation of a vortex and modification of the boundary layer, and increase in effective span by reduction of both spanwise flow and strength of the tip vortex. The tubercles provide a bio-inspired design that has commercial viability for wing-like structures. Control of passive flow has the advantages of eliminating complex, costly, high-maintenance, and heavy control mechanisms, while improving performance for lifting bodies in air and water. The tubercles on the leading edge can be applied to the design of watercraft, aircraft, ventilation fans, and windmills. C1 [Fish, Frank E.] W Chester Univ, Dept Biol, W Chester, PA 19383 USA. [Weber, Paul W.] Appl Res Associates Inc, Arlington, VA 22203 USA. [Murray, Mark M.] USN Acad, Dept Mech Engn, Annapolis, MD 21402 USA. [Howle, Laurens E.] Duke Univ, Dept Mech Engn & Mat Sci, Durham, NC 27708 USA. [Howle, Laurens E.] Duke Univ, Ctr Nonlinear & Complex Syst, Durham, NC 27708 USA. RP Fish, FE (reprint author), W Chester Univ, Dept Biol, W Chester, PA 19383 USA. EM ffish@wcupa.edu FU National Science Foundation [IOS-0640185]; National Defense Science and Engineering Graduate (NDSEG) Fellowship FX This work was supported by the National Science Foundation (F. E. F.; IOS-0640185) and the National Defense Science and Engineering Graduate (NDSEG) Fellowship (to P.W.W.). NR 78 TC 36 Z9 39 U1 4 U2 57 PU OXFORD UNIV PRESS INC PI CARY PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA SN 1540-7063 J9 INTEGR COMP BIOL JI Integr. Comp. Biol. PD JUL PY 2011 VL 51 IS 1 BP 203 EP 213 DI 10.1093/icb/icr016 PG 11 WC Zoology SC Zoology GA 786MY UT WOS:000292313800019 PM 21576119 ER PT J AU MacGregor, AJ Dougherty, AL Galarneau, MR AF MacGregor, Andrew J. Dougherty, Amber L. Galarneau, Michael R. TI Injury-Specific Correlates of Combat-Related Traumatic Brain Injury in Operation Iraqi Freedom SO JOURNAL OF HEAD TRAUMA REHABILITATION LA English DT Article DE combat; military; traumatic brain injury ID SEVERITY SCORE; REGISTRY; AFGHANISTAN; WARS; HEAD AB Background: The prevalence of traumatic brain injury (TBI) has increased during the wars in Iraq and Afghanistan compared with 20th century military conflicts. The aim of this study was to elucidate injury-specific correlates of combat-related TBI that have yet to be clearly defined. Participants: Predominately Marine US service members who sustained brain injuries in Iraq between March 2004 and April 2008 identified from clinical records completed in the theater of combat operations (n = 2074). Main Outcome Measures: Severity of TBI was classified as mild, moderate, or severe. Injury-specific factors, such as injury mechanism and type, were abstracted from the clinical records and were compared with severity of TBI. Results: Of all TBIs observed in the sample, 89% were mild. Higher severity of TBI was associated with an increased likelihood of sustaining the injury by gunshot and a lower likelihood of helmet use. Improvised explosive devices were associated with a preponderance of mild TBIs, and frequency of injuries in locations in addition to the head was highest among those with moderate and severe TBIs. Concomitant injuries to the spine/back were associated with blast injury mechanisms. Conclusions: Most incidents of TBI occurring during Operation Iraqi Freedom are mild in severity and a result of blast mechanisms. Multiple injuries were common, particularly as severity of TBI increased. Further research is needed to determine effects of combat-related TBI on rehabilitative and adverse health outcomes. C1 [MacGregor, Andrew J.; Dougherty, Amber L.; Galarneau, Michael R.] USN, Hlth Res Ctr, San Diego, CA 92106 USA. RP Dougherty, AL (reprint author), USN, Hlth Res Ctr, 140 Sylvester Rd, San Diego, CA 92106 USA. EM amber.dougherty@med.navy.mil FU US Navy Medicine Bureau of Medicine and Surgery, Washington, DC [60808] FX This work was supported by the US Navy Medicine Bureau of Medicine and Surgery, Washington, DC, under Work Unit No. 60808. The views and opinions expressed herein are those of the authors and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, or the US Government. This research has been conducted in compliance with all applicable federal regulations governing the protection of human subjects in research. NR 23 TC 24 Z9 24 U1 0 U2 1 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0885-9701 J9 J HEAD TRAUMA REHAB JI J. Head Trauma Rehabil. PD JUL-AUG PY 2011 VL 26 IS 4 BP 312 EP 318 DI 10.1097/HTR.0b013e3181e94404 PG 7 WC Clinical Neurology; Rehabilitation SC Neurosciences & Neurology; Rehabilitation GA 789FZ UT WOS:000292501700008 PM 20808241 ER PT J AU Hedelius, R Fletcher, JJ Glass, WF Susanti, AI Maguire, JD AF Hedelius, Richard Fletcher, James J. Glass, William F., II Susanti, Augustina I. Maguire, Jason D. TI Nephrotic Syndrome and Unrecognized Plasmodium malariae Infection in a US Navy Sailor 14 Years After Departing Nigeria SO JOURNAL OF TRAVEL MEDICINE LA English DT Article ID NORTHERN NIGERIA; IMMUNITY AB A 34-year-old Nigerian man presented with nephrotic syndrome. Renal biopsy revealed chronic membranous glomerulopathy with focal segmental sclerosis. Blood Giemsa smear contained rare Plasmodium sp. trophozoites and small subunit ribosomal RNA polymerase chain reaction amplification confirmed the presence of Plasmodium malariae. This case highlights the importance of obtaining even remote travel histories from ill immigrants and considering occult quartan malaria in patients from endemic locations with nephrotic syndrome. C1 [Hedelius, Richard; Fletcher, James J.; Maguire, Jason D.] USN, Med Ctr Portsmouth, Portsmouth, VA USA. [Glass, William F., II] Nephrocor & Bostwick Labs, Richmond, VA USA. [Susanti, Augustina I.] Naval Med Res Unit 2, Jakarta, Indonesia. RP Hedelius, R (reprint author), Dept Internal Med, Div Infect Dis, 620 John Paul Jones Circle, Portsmouth, VA 23708 USA. EM Richard.hedelius@med.navy.mil FU US Navy, Department of Defense FX The authors would like to acknowledge financial support from US Navy, Department of Defense. NR 16 TC 6 Z9 7 U1 0 U2 1 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 1195-1982 J9 J TRAVEL MED JI J. Travel Med. PD JUL-AUG PY 2011 VL 18 IS 4 BP 288 EP 291 DI 10.1111/j.1708-8305.2011.00526.x PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA 786KU UT WOS:000292307800013 PM 21722243 ER PT J AU Bradford, SF AF Bradford, Scott F. TI Nonhydrostatic Model for Surf Zone Simulation SO JOURNAL OF WATERWAY PORT COASTAL AND OCEAN ENGINEERING LA English DT Article DE Navier-Stokes; Surf zone; Wave propagation; Breaking wave ID BREAKING WAVES; BOUSSINESQ EQUATIONS; SHALLOW-WATER; NUMERICAL-SIMULATION; OVERTURNING WAVES; PLUNGING BREAKERS; TURBULENCE; DYNAMICS; PROPAGATION; VOLUME AB A previously developed model for nonhydrostatic free surface flow is adapted to simulate breaking waves in the surf zone. The model solves the Reynolds-averaged Navier-Stokes equations in a fraction step manner with the pressure split into hydrostatic and nonhydrostatic components. The hydrostatic equations are first solved with an approximate Riemann solver. This approach is particularly well suited for simulating discontinuous flow associated with breaking waves because the model prediction converges to the classical solution for a turbulent bore, which closely resembles breaking waves in the surf zone. The hydrostatic solution is then corrected by including the nonhydrostatic pressure. The model uses a sigma coordinate discretization in the vertical direction, which has been previously demonstrated to yield significant truncation errors with highly skewed grids over large bottom slopes. This potential problem is investigated in the context of highly skewed (but transient) grids that occur with steep breaking waves. C1 USN, Res Lab, Image Sci & Applicat Branch, Washington, DC 20375 USA. RP Bradford, SF (reprint author), USN, Res Lab, Image Sci & Applicat Branch, Code 7261, Washington, DC 20375 USA. EM scott.bradford@nrl.navy.mil NR 49 TC 15 Z9 17 U1 0 U2 5 PU ASCE-AMER SOC CIVIL ENGINEERS PI RESTON PA 1801 ALEXANDER BELL DR, RESTON, VA 20191-4400 USA SN 0733-950X EI 1943-5460 J9 J WATERW PORT COAST JI J. Waterw. Port Coast. Ocean Eng. PD JUL-AUG PY 2011 VL 137 IS 4 BP 163 EP 174 DI 10.1061/(ASCE)WW.1943-5460.0000079 PG 12 WC Engineering, Civil; Engineering, Ocean; Water Resources SC Engineering; Water Resources GA 789LV UT WOS:000292517900002 ER PT J AU Clenney, T Schroeder, A Bondy, P Zizak, V Mitchell, A AF Clenney, Timothy Schroeder, Ashley Bondy, Peter Zizak, Vincent Mitchell, Allen TI Postoperative Pain After Adult Tonsillectomy With Plasmaknife Compared to Monopolar Electrocautery SO LARYNGOSCOPE LA English DT Article DE Tonsillectomy; Plasma Knife; Bovie; postoperative pain ID RECOVERY; ELECTRODISSECTION; METAANALYSIS; ANTIBIOTICS; REDUCTION; COBLATION AB Objectives/Hypothesis: Monopolar cautery is the most commonly used technique for tonsillectomy. The aim of the present study is to compare postoperative pain using a new technology, Plasma Knife tonsillectomy (PKT), in comparison with monopolar cautery tonsillectomy (MCT). Study Design: Prospective, randomized, single-blinded, self-controlled study using paired organs. Methods: Thirty-two adult patients, aged 18 to 30 years, scheduled for tonsillectomy for recurrent tonsillitis were included. Patients were randomly assigned to undergo PKT on one side and MCT on the opposite side. The primary outcome was self-rated daily pain assessed by using a 10-point scale. Patients were provided 21-day pain diaries and were phoned twice weekly by a research assistant to assess pain and remind them to complete diaries. Secondary outcomes included comparisons of operative time, blood loss, and postoperative complications. Results: Repeated measures analysis of variance comparing PKT to MCT during the 21-day postoperative period revealed no difference in postoperative pain between the two groups (P = .131). In addition, total operative time (P = .276) and blood loss (P = .418) did not differ significantly between PKT and MCT. Conclusions: Adult subjects undergoing PKT do not experience less postoperative pain in comparison to MCT. C1 [Clenney, Timothy; Schroeder, Ashley; Bondy, Peter; Zizak, Vincent; Mitchell, Allen] USN, Med Ctr, Dept Otolaryngol Head & Neck Surg, Portsmouth, VA USA. RP Clenney, T (reprint author), 620 John Paul Jones Circle, Portsmouth, VA 23708 USA. EM timothy.clenney@med.navy.mil FU Navy Bureau of Medicine and Surgery, Washington, DC FX The Chief, Navy Bureau of Medicine and Surgery, Washington, DC, Clinical Investigation Program sponsored this study. The authors have no association with any products used in or inferred from this manuscript. Research data derived from Study Title, an approved Naval Medical Center, Portsmouth, VA IRB/IACUC protocol (CIP #2008.0052). The authors have no funding, financial relationships, or conflicts of interest to disclose. NR 17 TC 2 Z9 2 U1 1 U2 3 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 0023-852X J9 LARYNGOSCOPE JI Laryngoscope PD JUL PY 2011 VL 121 IS 7 BP 1416 EP 1421 DI 10.1002/lary.21806 PG 6 WC Medicine, Research & Experimental; Otorhinolaryngology SC Research & Experimental Medicine; Otorhinolaryngology GA 788DJ UT WOS:000292425300011 PM 21647905 ER PT J AU Chanda, D Shigeta, K Gupta, S Cain, T Carlson, A Mihi, A Baca, AJ Bogart, GR Braun, P Rogers, JA AF Chanda, Debashis Shigeta, Kazuki Gupta, Sidhartha Cain, Tyler Carlson, Andrew Mihi, Agustin Baca, Alfred J. Bogart, Gregory R. Braun, Paul Rogers, John A. TI Large-area flexible 3D optical negative index metamaterial formed by nanotransfer printing SO NATURE NANOTECHNOLOGY LA English DT Article ID NANOIMPRINT LITHOGRAPHY; TERAHERTZ FREQUENCIES; REFRACTIVE-INDEX; FABRICATION AB Negative-index metamaterials (NIMs) are engineered structures with optical properties that cannot be obtained in naturally occurring materials(1-3). Recent work has demonstrated that focused ion beam(4) and layer-by-layer electron-beamlithography(5) can be used to pattern the necessary nanoscale features over small areas (hundreds of mu m(2)) for metamaterials with three-dimensional layouts and interesting characteristics, including negative-index behaviour in the optical regime. A key challenge is in the fabrication of such three-dimensional NIMs with sizes and at throughputs necessary for many realistic applications (including lenses, resonators and other photonic components(6-8)). We report a simple printing approach capable of forming large-area, high-quality NIMs with three-dimensional, multilayer formats. Here, a silicon wafer with deep, nanoscale patterns of surface relief serves as a reusable stamp. Blanket deposition of alternating layers of silver and magnesium fluoride onto such a stamp represents a process for 'inking' it with thick, multilayer assemblies. Transfer printing this ink material onto rigid or flexible substrates completes the fabrication in a high-throughput manner. Experimental measurements and simulation results show that macroscale, three-dimensional NIMs (>75 cm(2)) nano-manufactured in this way exhibit a strong, negative index of refraction in the near-infrared spectral range, with excellent figures of merit. C1 [Chanda, Debashis; Shigeta, Kazuki; Gupta, Sidhartha; Cain, Tyler; Carlson, Andrew; Mihi, Agustin; Braun, Paul; Rogers, John A.] Univ Illinois, Dept Mat Sci, Beckman Inst, Urbana, IL 61801 USA. [Chanda, Debashis; Shigeta, Kazuki; Gupta, Sidhartha; Cain, Tyler; Carlson, Andrew; Mihi, Agustin; Braun, Paul; Rogers, John A.] Univ Illinois, Dept Engn, Beckman Inst, Urbana, IL 61801 USA. [Chanda, Debashis; Shigeta, Kazuki; Gupta, Sidhartha; Cain, Tyler; Carlson, Andrew; Mihi, Agustin; Braun, Paul; Rogers, John A.] Univ Illinois, Frederick Seitz Mat Res Lab, Urbana, IL 61801 USA. [Rogers, John A.] Univ Illinois, Dept Mech Sci & Engn, Urbana, IL 61801 USA. [Baca, Alfred J.] USN, NAVAIR NAWCWD, Res & Intelligence Dept, Chem Branch, China Lake, CA 93555 USA. [Bogart, Gregory R.] Sandia Natl Labs, Albuquerque, NM 87185 USA. RP Rogers, JA (reprint author), Univ Illinois, Dept Mat Sci, Beckman Inst, Urbana, IL 61801 USA. EM jrogers@uiuc.edu RI Mihi, Agustin/F-6416-2011; Rogers, John /L-2798-2016 FU Office of Naval Research; US Department of Energy [DE-AC04-94AL85000] FX The work at University of Illinois was supported by a grant from the Office of Naval Research. The authors also gratefully knowledge the contribution of Sandia National Laboratory, which is a multi-programme laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the US Department of Energy (contract no. DE-AC04-94AL85000), in fabricating the large-area master mask using deep UV lithography. NR 35 TC 150 Z9 153 U1 36 U2 329 PU NATURE PUBLISHING GROUP PI LONDON PA MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND SN 1748-3387 EI 1748-3395 J9 NAT NANOTECHNOL JI Nat. Nanotechnol. PD JUL PY 2011 VL 6 IS 7 BP 402 EP 407 DI 10.1038/NNANO.2011.82 PG 6 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Science & Technology - Other Topics; Materials Science GA 788RV UT WOS:000292463000007 PM 21642984 ER PT J AU Okasha, NM Frangopol, DM Saydam, DG Salvino, LW AF Okasha, Nader M. Frangopol, Dan M. Saydam, Duygu Salvino, Liming W. TI Reliability analysis and damage detection in high-speed naval craft based on structural health monitoring data SO STRUCTURAL HEALTH MONITORING-AN INTERNATIONAL JOURNAL LA English DT Article DE structural health monitoring; damage detection; vector autoregressive modeling; reliability; naval craft ID TIME-SERIES ANALYSIS; LOCALIZATION AB Current and future trends in naval craft design are leaning toward the development of high-speed and high-performance vessels. Lack of information on wave-induced loads for these vessels presents a challenge in ensuring their safety that is best tackled with monitoring operational loads and detecting damage via structural health monitoring (SHM) systems. These monitoring systems, however, require efficient statistical and probabilistic procedures that are able to effectively treat the uncertainties inherent in the massive volumes of collected data and provide interpretable information regarding the reliability and condition of the craft structure. In this article, an approach for using SHM data in the reliability analysis and damage detection in high-speed naval craft (HSNC) under uncertainty is presented. This statistical damage detection technique makes use of vector autoregressive modeling for detection and localization of damage in the ship structure. The methodology is illustrated on an HSNC, HSV-2. Data obtained from seakeeping trials of HSV-2 were treated as the SHM data mentioned above. C1 [Okasha, Nader M.; Frangopol, Dan M.; Saydam, Duygu] Lehigh Univ, Dept Civil & Environm Engn, Engn Res Ctr Adv Technol Large Struct Syst ATLSS, Bethlehem, PA 18015 USA. [Salvino, Liming W.] NSWC, Carderock Div, Struct & Composite Code 652, Bethesda, MD 20817 USA. RP Frangopol, DM (reprint author), Lehigh Univ, Dept Civil & Environm Engn, Engn Res Ctr Adv Technol Large Struct Syst ATLSS, Bethlehem, PA 18015 USA. EM dan.frangopol@lehigh.edu FU Office of Naval Research [N-00014-08-0188] FX The support from the Office of Naval Research to Lehigh University under award N-00014-08-0188 is gratefully acknowledged. The authors greatly appreciate the technical guidance and overall support from Mr Thomas Brady, Code 653, Naval Surface Warfare Center, Carderock Division (NSWCCD), for providing the data and other materials. The opinions and conclusions presented in this article are those of the authors and do not necessarily reflect the views of the sponsoring organization. NR 32 TC 14 Z9 15 U1 0 U2 11 PU SAGE PUBLICATIONS LTD PI LONDON PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND SN 1475-9217 J9 STRUCT HEALTH MONIT JI Struct. Health Monit. PD JUL PY 2011 VL 10 IS 4 BP 361 EP 379 DI 10.1177/1475921710379516 PG 19 WC Engineering, Multidisciplinary; Instruments & Instrumentation SC Engineering; Instruments & Instrumentation GA 788PL UT WOS:000292456800003 ER PT J AU Stromdahl, EY Jiang, J Vince, M Richards, AL AF Stromdahl, Ellen Y. Jiang, Ju Vince, Mary Richards, Allen L. TI Infrequency of Rickettsia rickettsii in Dermacentor variabilis Removed from Humans, with Comments on the Role of Other Human-Biting Ticks Associated with Spotted Fever Group Rickettsiae in the United States SO VECTOR-BORNE AND ZOONOTIC DISEASES LA English DT Article DE Amblyomma; Dermacentor; Rhiphicephalus; Rickettsia; Tick(s); Vector-borne; Zoonosis ID AMBLYOMMA-AMERICANUM ACARI; BROWN DOG TICK; RHIPICEPHALUS-SANGUINEUS ACARI; NORTH-CAROLINA; HUMAN PARASITISM; IXODIDAE; VECTOR; PREVALENCE; ANDERSONI; INFECTION AB From 1997 to 2009, the Tick-Borne Disease Laboratory of the U. S. Army Public Health Command (USAPHC) (formerly the U. S. Army Center for Health Promotion and Preventive Medicine) screened 5286 Dermacentor variabilis ticks removed from Department of Defense (DOD) personnel, their dependents, and DOD civilian personnel for spotted fever group rickettsiae using polymerase chain reaction and restriction fragment length polymorphism analysis. Rickettsia montanensis (171/5286 = 3.2%) and Rickettsia amblyommii (7/5286 = 0.1%) were detected in a small number of samples, but no ticks were found positive for Rickettsia rickettsii, the agent of Rocky Mountain spotted fever (RMSF) until May 2009, when it was detected in one D. variabilis male removed from a child in Maryland. This result was confirmed by nucleotide sequence analysis of the rickettsial isolate and of the positive control used in the polymerase chain reaction, which was different from the isolate. Lethal effects of rickettsiostatic proteins of D. variabilis on R. rickettsii and lethal effects of R. rickettsii infection on tick hosts may account for this extremely low prevalence. Recent reports of R. rickettsii in species Rhipicephalus sanguineus and Amblyomma americanum ticks suggest their involvement in transmission of RMSF, and other pathogenic rickettsiae have been detected in Amblyomma maculatum. The areas of the U. S. endemic for RMSF are also those where D. variabilis exist in sympatry with populations of A. americanum and A. maculatum. Interactions among the sympatric species of ticks may be involved in the development of a focus of RMSF transmission. On the other hand, the overlap of foci of RMSF cases and areas of A. americanum and A. maculatum populations might indicate the misdiagnosis as RMSF of diseases actually caused by other rickettsiae vectored by these ticks. Further studies on tick vectors are needed to elucidate the etiology of RMSF. C1 [Stromdahl, Ellen Y.; Vince, Mary] USA, Entomol Sci Program, Publ Hlth Command, Aberdeen Proving Ground, MD 21010 USA. [Jiang, Ju; Richards, Allen L.] USN, Viral & Rickettsial Dis Dept, Med Res Ctr, Silver Spring, MD USA. [Richards, Allen L.] Uniformed Serv Univ Hlth Sci, Prevent Med & Boimetr Dept, Bethesda, MD 20814 USA. RP Stromdahl, EY (reprint author), USA, Entomol Sci Program, Publ Hlth Command Provis, 5158 Blackhawk Rd,BLDG E-5800, Aberdeen Proving Ground, MD 21010 USA. EM ellen.stromdahl@us.army.mil RI Valle, Ruben/A-7512-2013 NR 50 TC 36 Z9 37 U1 1 U2 27 PU MARY ANN LIEBERT INC PI NEW ROCHELLE PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA SN 1530-3667 J9 VECTOR-BORNE ZOONOT JI Vector-Borne Zoonotic Dis. PD JUL PY 2011 VL 11 IS 7 BP 969 EP 977 DI 10.1089/vbz.2010.0099 PG 9 WC Public, Environmental & Occupational Health; Infectious Diseases SC Public, Environmental & Occupational Health; Infectious Diseases GA 789TV UT WOS:000292540100028 PM 21142953 ER PT J AU Rouillard, AP Odstrcil, D Sheeley, NR Tylka, A Vourlidas, A Mason, G Wu, CC Savani, NP Wood, BE Ng, CK Stenborg, G Szabo, A St Cyr, OC AF Rouillard, A. P. Odstrcil, D. Sheeley, N. R., Jr. Tylka, A. Vourlidas, A. Mason, G. Wu, C-C Savani, N. P. Wood, B. E. Ng, C. K. Stenborg, G. Szabo, A. St Cyr, O. C. TI INTERPRETING THE PROPERTIES OF SOLAR ENERGETIC PARTICLE EVENTS BY USING COMBINED IMAGING AND MODELING OF INTERPLANETARY SHOCKS SO ASTROPHYSICAL JOURNAL LA English DT Article DE acceleration of particles; shock waves; Sun: coronal mass ejections (CMEs) ID CORONAL MASS EJECTION; ADVANCED COMPOSITION EXPLORER; WIND SPACECRAFT; STEREO MISSION; DRIVEN SHOCKS; ALPHA MONITOR; WHITE-LIGHT; SUN; ACCELERATION; TELESCOPE AB Images of the solar corona obtained by the Solar-Terrestrial Relations Observatory (STEREO) provide high-cadence, high-resolution observations of a compression wave forming ahead of a fast (940 km s(-1)) coronal mass ejection (CME) that erupted at similar to 9:00 UT on 2010 April 03. The passage of this wave at 1 AU is detected in situ by the Advanced Composition Explorer and Wind spacecraft at 08: 00 UT on April 05 as a shock followed by a turbulent and heated sheath. These unprecedented and complementary observations of a shock-sheath region from the Sun to 1 AU are used to investigate the onset of a Solar Energetic Particle (SEP) event measured at the first Lagrange point (L1) and at STEREO-Behind (STB). The spatial extent, radial coordinates, and speed of the ejection are measured from STEREO observations and used as inputs to a numerical simulation of the CME propagation in the background solar wind. The simulated magnetic and plasma properties of the shock and sheath region at L1 agree very well with the in situ measurements. These simulation results reveal that L1 and STB are magnetically connected to the western and eastern edges of the driven shock, respectively. They also show that the 12 hr delay between the eruption time of the ejection and the SEP onset at L1 corresponds to the time required for the bow shock to reach the magnetic field lines connected with L1. The simulated shock compression ratio increases along these magnetic field lines until the maximum flux of high-energy particles is observed. C1 [Rouillard, A. P.; Odstrcil, D.; Ng, C. K.] George Mason Univ, Coll Sci, Fairfax, VA 22030 USA. [Rouillard, A. P.; Odstrcil, D.; Szabo, A.; St Cyr, O. C.] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA. [Sheeley, N. R., Jr.; Tylka, A.; Vourlidas, A.; Wu, C-C; Wood, B. E.; Ng, C. K.] USN, Res Lab, Washington, DC 20375 USA. [Mason, G.] JHU Appl Phys Lab, Laurel, MD USA. [Savani, N. P.] Univ London Imperial Coll Sci Technol & Med, Blackett Lab, London SW7 2BW, England. [Stenborg, G.] Interferometrics Inc, Herndon, VA USA. RP Rouillard, AP (reprint author), George Mason Univ, Coll Sci, Fairfax, VA 22030 USA. RI Savani, Neel/G-4066-2014; Tylka, Allan/G-9592-2014; Vourlidas, Angelos/C-8231-2009 OI Savani, Neel/0000-0002-1916-7877; Vourlidas, Angelos/0000-0002-8164-5948 FU NASA [NNX11AD40G-45527, NNXIOAT06G, NNX09AU98G, NMX07AN45G, NNH09AK79I]; University of Berkeley (STEREO SIT) [SA4889-26309] FX We thank the referee for his many constructive suggestions. We also thank Yi-Ming Wang and Judith Lean for their continual support. The STEREO SECCHI data are produced by a consortium of RAL (UK), NRL (USA), LMSAL (USA), GSFC (USA), MPS (Germany), CSL (Belgium), IOTA (France), and IAS (France). The ACE data were obtained from the ACE science center. The WIND data were obtained from the Space Physics Data Facility. The SECCHI images were obtained from the World Data Center, Chilton, UK and the Naval Research Laboratory, Washington, DC, USA. The work of A. P. R. was partly funded by NASA contracts NNX11AD40G-45527 and NNXIOAT06G and that of C.K.N. was partially supported by NASA Grant NNX09AU98G. NASA contract SA4889-26309 from University of Berkeley (STEREO SIT) and NASA grant NMX07AN45G permitted the preparation and calibration of the ULEIS and SIT data. A.J.T. was supported in part by NASA grant NNH09AK79I. The NRL employees acknowledge support from the Office of Naval Research and NASA. NR 63 TC 54 Z9 55 U1 0 U2 5 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X J9 ASTROPHYS J JI Astrophys. J. PD JUL 1 PY 2011 VL 735 IS 1 AR 7 DI 10.1088/0004-637X/735/1/7 PG 11 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 779OM UT WOS:000291788300007 ER PT J AU Scholnik, DP AF Scholnik, Dan P. TI Convex-Programming Design of Linear and Nonlinear Phase Wideband Blocking Filters SO IEEE TRANSACTIONS ON SIGNAL PROCESSING LA English DT Article DE Blocking filter; blocking matrix; FIR filter design; notch filter; second-order cone programming; spectral factorization; wideband arrays ID 2-DIMENSIONAL SPECTRAL FACTORIZATION; DIGITAL-FILTERS; SIGNAL CANCELLATION; COHERENT JAMMERS; ADAPTIVE ARRAY; INTERFERENCE; OPTIMIZATION; PERFORMANCE; MATRIX AB Blocking filters are commonly used in array processing to excise targets from data when suitable target-free training data is not available. A drawback is the reduction of the effective size of the array by the order of the filter, motivating a search for the smallest filter that meets the design specifications. Common linear-phase approaches lead to convex optimization and efficient global solutions, but can be inefficient when the phase of the blocking filter is unimportant. Although direct magnitude-response optimization is nonconvex in general, for narrowband linear arrays optimal-magnitude blocking filters can be found using constrained optimization followed by spectral factorization. This approach cannot be directly applied to wideband arrays, as finite-support spectral factors do not generally exist in higher dimensions. Instead, a procedure is presented in which an approximate multidimensional spectral factor of an optimized spectral density is used as a target response in a second optimization stage. Linear and nonlinear-phase solutions are found and compared for both narrowband and wideband notch filters, with the nonlinear phase outperforming the linear phase in both notch width and passband error. The various optimizations are performed using second-order cone programming, an efficient class of convex optimization. C1 USN, Div Radar, Res Lab, Washington, DC 20375 USA. RP Scholnik, DP (reprint author), USN, Div Radar, Res Lab, Washington, DC 20375 USA. EM dan.scholnik@nrl.navy.mil FU Office of Naval Research; Naval Research Laboratory FX Manuscript received June 03, 2010; revised December 06, 2010 and March 17, 2011; accepted April 01, 2011. Date of publication April 11, 2011; date of current version June 15, 2011. The associate editor coordinating the review of this paper and approving it for publication was Dr. Soontorn Oraintara. This work was supported by the Office of Naval Research and by the Naval Research Laboratory base program. NR 44 TC 2 Z9 2 U1 0 U2 2 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1053-587X J9 IEEE T SIGNAL PROCES JI IEEE Trans. Signal Process. PD JUL PY 2011 VL 59 IS 7 BP 3133 EP 3142 DI 10.1109/TSP.2011.2141662 PG 10 WC Engineering, Electrical & Electronic SC Engineering GA 778DM UT WOS:000291680200012 ER PT J AU Sivaprakasam, V Lou, JW Currie, M Eversole, JD AF Sivaprakasam, Vasanthi Lou, Janet W. Currie, Marc Eversole, Jay D. TI Two-photon excited fluorescence from biological aerosol particles SO JOURNAL OF QUANTITATIVE SPECTROSCOPY & RADIATIVE TRANSFER LA English DT Article DE Laser induced fluorescence; Particle scattering; 2-Photon excitation; Aerosol; Biological particle ID LASER-INDUCED FLUORESCENCE; MULTIPHOTON EXCITATION; VISIBLE EMISSION; 5-HYDROXYTRYPTOPHAN; CLASSIFICATION; SCATTERING AB We used a 40 MHz mode-locked 524 nm laser source to evaluate the utility of sub-picosecond excitation of fluorescence from 2-photon absorption in biological aerosols. Individual particles of biological composition, as well as other calibration particles, suspended in an inlet air flow were illuminated and measured as they passed through an optical chamber. To our knowledge, this was the first demonstration of 2-photon excited fluorescence from micron-sized particles composed of micro-organisms. We also observed a high fluorescence signal at visible wavelengths, which was not present with single-photon excitation. Published by Elsevier Ltd. C1 [Sivaprakasam, Vasanthi; Currie, Marc; Eversole, Jay D.] USN, Div Opt Sci, Res Lab, Washington, DC 20375 USA. [Lou, Janet W.] USN, Global Def Technol & Syst Inc, Mission Syst Div, Res Lab, Washington, DC 20375 USA. RP Sivaprakasam, V (reprint author), USN, Div Opt Sci, Res Lab, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM vasanthi.sivaprakasam@nrl.navy.mil FU DTRA FX This work was supported by DTRA. The Defense Threat Reduction Agency (DTRA) was founded in 1998 to integrate and focus the capabilities of the Department of Defense that address the weapons of Mass Destruction (WMD) threat. The mission of the DTRA is to safeguard America and its allies from WMD threat (e.g. chemical, biological, radiological, nuclear and high yield explosives) by providing capabilities to reduce, eliminate and counter the threat and mitigate its effects. Under DTRA, Department of Defense resources, expertise and capabilities are combined to ensure the United States remains ready and able to address the present and future WMD threats. For more information on DTRA, visit _www.dtra.mil_ file://www.dtra.mil. NR 22 TC 2 Z9 2 U1 0 U2 15 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0022-4073 J9 J QUANT SPECTROSC RA JI J. Quant. Spectrosc. Radiat. Transf. PD JUL PY 2011 VL 112 IS 10 BP 1511 EP 1517 DI 10.1016/j.jqsrt.2011.02.010 PG 7 WC Optics; Spectroscopy SC Optics; Spectroscopy GA 778OS UT WOS:000291714600001 ER PT J AU Arnaud, F Teranishi, K Okada, T Parreno-Sacdalan, D Hupalo, D McNamee, G Carr, W Burris, D McCarron, R AF Arnaud, Francoise Teranishi, Kohsuke Okada, Tomoaki Parreno-Sacdalan, Dione Hupalo, Daniel McNamee, George Carr, Walter Burris, David McCarron, Richard TI Comparison of Combat Gauze and TraumaStat in Two Severe Groin Injury Models SO JOURNAL OF SURGICAL RESEARCH LA English DT Article DE hemorrhage; bleeding control; hemostatic dressings; bandages; trauma; hemostasis; swine models ID EXTREMITY ARTERIAL HEMORRHAGE; HEMOSTATIC AGENT; LIFE-SUPPORT; LETHAL MODEL; SWINE; DRESSINGS; EFFICACY; QUIKCLOT AB Background. Fabric-like hemostatic dressings offer promise for hemorrhage control in noncompressible areas, especially given their similarity in form to standard gauze currently in use. Recently, two such products, Combat Gauze (CBG) and TraumaStat (TMS), were introduced. Their performance is evaluated in two vascular injury models. Materials and Methods. The dressings were evaluated in anesthetized Yorkshire pigs, hemorrhaged by full transection of the femoral vasculature with 2 min free bleeding period (CBG [ 6, TMS [ 6) or by 4 mm femoral arterial puncture with 45 s free bleeding period (CBG [ 8, TMS [ 8). After injury, dressings were applied, followed by 5 min of manual compression and then 500 mL resuscitation fluid infused over 30 min. Vital signs, blood pressure, and blood loss were recorded throughout the 3-h experiment. Bleeding control was the primary outcome. Results. All animals had similar pretreatment mean arterial pressure (MAP) (similar to 36.5 mmHg); pretreatment blood loss following injury was similar for both dressing groups in the two models [24% +/- 8% estimated blood volume (EBV) 2 min after transection and 17% +/- 4% EBV45 s after puncture. Incidence of post-treatment bleeding, primarily occurring after release of manual compression or restoration of blood pressure, was more frequent in the puncture model (17% with both CBG and TMS) than the transection model (57% with CBG versus 75% with TMS). Post-treatment blood loss not controlled by the dressing was 19% +/- 22% and 31% +/- 17% EBV, for CBG and TMS, respectively. Survival rate was 100% for both dressings in the transection model, and was 88% for CBG and 50% for TMS in the puncture model. Conclusions. These findings indicated that CBG and TMS were similarly effective in improving hemostasis. These two fabric-like dressings showed easy application and removal, leaving a clean wound for surgical repair. (C) 2011 Elsevier Inc. All rights reserved. C1 [Arnaud, Francoise] USN, Med Res Ctr, RMD, Dept Trauma & Resuscitat Med, Silver Spring, MD 20910 USA. [Arnaud, Francoise; Parreno-Sacdalan, Dione; McNamee, George; Burris, David; McCarron, Richard] Uniformed Serv Univ Hlth Sci, Dept Surg, Bethesda, MD 20814 USA. RP Arnaud, F (reprint author), USN, Med Res Ctr, RMD, Dept Trauma & Resuscitat Med, 503 Robert Grant Ave, Silver Spring, MD 20910 USA. EM francoise.Arnaud@med.navy.mil FU MARCORSYSCOM [206623 M.162 M.A0607] FX The authors thank Drs. T. Tomori, A. Scultetus, A. Haque, M. Hammett, B. Kim, and N. Carballo for surgical and technical assistance, and J. Norris for editorial support. The authors are grateful to Z-Medica, Wallingford, CT and OreMedix for providing the test materials. Research effort was supported by MARCORSYSCOM 206623 M.162 M.A0607. NR 15 TC 12 Z9 14 U1 0 U2 8 PU ACADEMIC PRESS INC ELSEVIER SCIENCE PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA SN 0022-4804 J9 J SURG RES JI J. Surg. Res. PD JUL PY 2011 VL 169 IS 1 BP 92 EP 98 DI 10.1016/j.jss.2009.09.004 PG 7 WC Surgery SC Surgery GA 778ED UT WOS:000291682500028 PM 20070980 ER PT J AU Kaplan, I Sardanelli, S Rehill, BJ Denno, RF AF Kaplan, Ian Sardanelli, Sandra Rehill, Brian J. Denno, Robert F. TI Toward a mechanistic understanding of competition in vascular-feeding herbivores: an empirical test of the sink competition hypothesis SO OECOLOGIA LA English DT Article DE Above-belowground interactions; Induced plant resistance; Interspecific competition; Plant-mediated interactions ID PLANT-MEDIATED INTERACTIONS; GROUND-INDUCED RESPONSES; MELOIDOGYNE-INCOGNITA; HOST-PLANT; INTERSPECIFIC INTERACTIONS; PHYTOPHAGOUS INSECTS; NICOTIANA-TABACUM; CARBON; APHID; ROOT AB Recent evidence suggests that competitive interactions among herbivores are mostly indirect and mediated by plant responses to herbivory. Most studies, however, emphasize chewing insects and secondary chemistry, thus ignoring the diverse group of vascular-parasites that may be more likely to compete through induced changes in phytonutrients. Using an aboveground phloem-feeding aphid (Myzus persicae) and a belowground gall-forming nematode (Meloidogyne incognita) on tobacco plants, we assessed the importance of competition via induced host-plant sinks. In a series of experimental trials, nematode root herbivory caused 55 and 72% declines in the growth and fecundity of aphids, respectively. Aphids, on the other hand, did not impact nematode performance. Therefore, we predicted that nematodes out-compete M. persicae by attenuating the magnitude of aphid-induced sinks. Through a combination of invertase enzyme measurements and stable isotope ((13)C and (15)N) enrichment, we found evidence that both herbivores act as mobilizing sinks. Aphids attracted photoassimilates to feeding aggregations on leaves and nematode galls accumulated resources in the roots. Levels of invertase enzymes, for example, were more than fourfold higher in nematode galls than in surrounding root tissue. Yet we found no evidence supporting a sink competition model for aphid-nematode interactions. The strength of aphid-induced leaf sinks was entirely unaffected by nematode presence, and vice versa. Thus, induced host-plant sinks appear to be a common strategy employed by vascular parasites to manipulate the physiology of their host, but multi-sink competition may be limited to herbivores that co-occur on the same tissue type and/or plants under growth-limited abiotic conditions. C1 [Kaplan, Ian] Purdue Univ, Dept Entomol, W Lafayette, IN 47907 USA. [Sardanelli, Sandra; Denno, Robert F.] Univ Maryland, Dept Entomol, College Pk, MD 20742 USA. [Rehill, Brian J.] USN Acad, Dept Chem, Annapolis, MD USA. RP Kaplan, I (reprint author), Purdue Univ, Dept Entomol, W Lafayette, IN 47907 USA. EM ikaplan@purdue.edu NR 58 TC 26 Z9 26 U1 3 U2 60 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 0029-8549 J9 OECOLOGIA JI Oecologia PD JUL PY 2011 VL 166 IS 3 BP 627 EP 636 DI 10.1007/s00442-010-1885-9 PG 10 WC Ecology SC Environmental Sciences & Ecology GA 777HI UT WOS:000291606100006 PM 21181415 ER PT J AU Haukoos, JS Hopkins, E Hull, A Dean, C Donahoe, K Ruzas, CM Bauerle, JD Terrien, B Forsyth, J Kalish, B Thrun, M Rothman, R AF Haukoos, Jason S. Hopkins, Emily Hull, Amber Dean, Christian Donahoe, Kevin Ruzas, Christopher M. Bauerle, Jessica D. Terrien, Brian Forsyth, Jessica Kalish, Brian Thrun, Mark Rothman, Richard TI HIV Testing in Emergency Departments in the United States: A National Survey SO ANNALS OF EMERGENCY MEDICINE LA English DT Article; Proceedings Paper CT Annual Meeting of the Society-for-Academic-Emergency-Medicine CY MAY 13-17, 2009 CL New Orleans, LA SP Soc Acad Emergency Med ID HUMAN-IMMUNODEFICIENCY-VIRUS; FOR-DISEASE-CONTROL; PREVENTION; RECOMMENDATIONS; HEALTH; CARE AB Objectives: In 2006, the Centers for Disease Control and Prevention (CDC) published recommendations for HIV testing in health care settings, calling for nontargeted opt-out rapid HIV screening in most settings, including emergency departments (EDs). Although a number of ED-based testing strategies exist, it is unclear to what extent they are used. The objective of this study is to survey academic and community EDs throughout the United States to determine ED-based HIV testing practices. Methods: This was a cross-sectional survey study of all academic EDs and a weighted random sample of all community-based EDs in the United States. A standardized survey instrument was developed and administered with an Internet-based survey platform, followed by direct contact and mail. The survey included domains related to perceived HIV testing barriers, whether HIV testing was performed and methods used, and familiarity with the CDC recommendations and whether they had been adopted. Results: Of the 131 total academic sites and the 435 community sites, 99 (76%) and 150 (35%) completed the survey, respectively. A larger proportion of academic sites believed HIV testing was needed (P=.02) and a larger proportion actually provided HIV testing (65% versus 50%; P=.04). Among the academic and community EDs that provided testing, 74% and 62% performed diagnostic testing, 26% and 22% performed targeted screening, and 16% and 6% performed nontargeted screening, respectively. A larger proportion of academic EDs reported receiving external funding to support testing (23% versus 4%; P=.001), whereas a large proportion of community sites considered costs a significant barrier to testing (P=.03). A larger proportion of academic EDs reported being familiar with the 2006 CDC recommendations (64% versus 40%; P<.001), although only 26% and 37% reported having implemented any part of them, respectively. Conclusion: Academic EDs only make up approximately 3% of all EDs in the United States. Significant differences exist between academic and community EDs as they relate to performing HIV testing. Increased efforts should be made to improve the ability of community EDs to provide this service. [Ann Emerg Med. 2011; 58:S10-S16.] C1 [Haukoos, Jason S.; Hopkins, Emily] Denver Hlth Med Ctr, Dept Emergency Med, Denver, CO 80204 USA. [Thrun, Mark] Denver Hlth Med Ctr, Div Infect Dis, Denver, CO 80204 USA. [Haukoos, Jason S.] Colorado Sch Publ Hlth, Dept Epidemiol, Aurora, CO USA. [Haukoos, Jason S.; Ruzas, Christopher M.; Bauerle, Jessica D.; Thrun, Mark] Univ Colorado Denver Sch Med, Aurora, CO USA. [Hull, Amber] Childrens Hosp, Div Pediat Endocrinol, Aurora, CO USA. [Dean, Christian] Univ N Texas Hlth Sci Ctr, Texas Coll Osteopath Med, Ft Worth, TX USA. [Donahoe, Kevin] St Louis Univ, Sch Med, St Louis, MO USA. [Terrien, Brian] USN, San Diego Med Ctr, San Diego, CA 92152 USA. [Forsyth, Jessica] Childrens Hosp, Immunodeficiency Program, Aurora, CO USA. [Kalish, Brian; Rothman, Richard] Johns Hopkins Univ, Dept Emergency Med, Baltimore, MD USA. [Kalish, Brian] Harvard Univ, Sch Med, Boston, MA USA. [Thrun, Mark] Denver Publ Hlth, Denver, CO USA. RP Haukoos, JS (reprint author), Denver Hlth Med Ctr, Dept Emergency Med, 777 Bannock St,Mail Code 0108, Denver, CO 80204 USA. EM Jason.Haukoos@dhha.org OI Rothman, Richard/0000-0002-1017-9505 FU AHRQ HHS [K02 HS017526]; NCHHSTP CDC HHS [U18 PS000314] NR 18 TC 20 Z9 20 U1 0 U2 4 PU MOSBY-ELSEVIER PI NEW YORK PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA SN 0196-0644 J9 ANN EMERG MED JI Ann. Emerg. Med. PD JUL PY 2011 VL 58 IS 1 SU S BP S10 EP S16 DI 10.1016/j.annemergmed.2011.03.033 PG 7 WC Emergency Medicine SC Emergency Medicine GA 786XM UT WOS:000292341200004 PM 21684387 ER PT J AU Leski, TA Malanoski, AP Gregory, MJ Lin, BC Stenger, DA AF Leski, Tomasz A. Malanoski, Anthony P. Gregory, Michael J. Lin, Baochuan Stenger, David A. TI Application of a Broad-Range Resequencing Array for Detection of Pathogens in Desert Dust Samples from Kuwait and Iraq SO APPLIED AND ENVIRONMENTAL MICROBIOLOGY LA English DT Article ID AL-ESKAN-DISEASE; REAL-TIME PCR; Q-FEVER; DNA MICROARRAYS; BACTERIAL IDENTIFICATION; MYCOBACTERIUM-FORTUITUM; COXIELLA-BURNETII; BIOTHREAT AGENTS; UNITED-STATES; US MILITARY AB A significant percentage of the human population is exposed to high levels of naturally occurring airborne dusts. Although the link between airborne particulate inhalation and a variety of respiratory diseases has long been established, little is known about the pathogenic role of the microbial component of the dust. In this study, we applied highly multiplexed PCR and a high-density resequencing microarray (RPM-TEI version 1.0) to screen samples of fine topsoil particles and airborne dust collected in 19 locations in Iraq and Kuwait for the presence of a broad range of human pathogens. The results indicated the presence of potential human pathogens, including Mycobacterium, Brucella, Coxiella burnetii, Clostridium perfringens, and Bacillus. The presence of Coxiella burnetii, a highly infectious potential biowarfare agent, was confirmed and detected in additional samples by use of a more sensitive technique (real-time PCR), indicating a high prevalence of this organism in the analyzed samples. The detection of potentially viable pathogens in breathable dusts from arid regions of Iraq and Kuwait underscores the importance of further study of these environments. C1 [Leski, Tomasz A.; Malanoski, Anthony P.; Lin, Baochuan; Stenger, David A.] USN, Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. [Gregory, Michael J.] USN, Res Lab, Div Chem, Washington, DC 20375 USA. RP Leski, TA (reprint author), USN, Res Lab, Ctr Bio Mol Sci & Engn, Code 6900,4555 Overlook Ave SW, Washington, DC 20375 USA. EM tomasz.leski@nrl.navy.mil RI Malanoski, Anthony/C-7814-2011; Leski, Tomasz/K-6916-2013; Lin, Baochuan/A-8390-2009 OI Malanoski, Anthony/0000-0001-6192-888X; Leski, Tomasz/0000-0001-7688-9887; Lin, Baochuan/0000-0002-9484-0785 FU Office of Naval Research FX The funding for developing the RPM-TEI array was provided by the Office of Naval Research. NR 63 TC 21 Z9 23 U1 2 U2 8 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA SN 0099-2240 J9 APPL ENVIRON MICROB JI Appl. Environ. Microbiol. PD JUL PY 2011 VL 77 IS 13 BP 4285 EP 4292 DI 10.1128/AEM.00021-11 PG 8 WC Biotechnology & Applied Microbiology; Microbiology SC Biotechnology & Applied Microbiology; Microbiology GA 782CR UT WOS:000291985700003 PM 21571877 ER PT J AU Nichols, JM Moore, EZ Murphy, KD AF Nichols, J. M. Moore, E. Z. Murphy, K. D. TI Bayesian identification of a cracked plate using a population-based Markov Chain Monte Carlo method SO COMPUTERS & STRUCTURES LA English DT Article DE Bayesian inference; Population-based Markov Chain Monte Carlo; System identification; Damage identification ID DIFFERENTIAL EVOLUTION; DAMAGE DETECTION; SIMULATION; OPTIMIZATION; MODELS AB Estimating damage in structural systems is a challenging problem due to the complexity of the likelihood function describing the observed data. From a Bayesian perspective a complicated likelihood means efficient sampling of the posterior distribution is difficult and standard Markov Chain Monte Carlo samplers may no longer be sufficient. This work describes a population-based Markov Chain Monte Carlo approach for efficient sampling of the damage parameter posterior distributions. The approach is shown to accurately estimate the state of damage in a cracked plate structure using simulated, free-decay response data. The use of this approach in identifying structural damage has not previously been explored. Published by Elsevier Ltd. C1 [Nichols, J. M.] USN, Res Lab, Washington, DC 20375 USA. [Moore, E. Z.; Murphy, K. D.] Univ Connecticut, Dept Mech Engn, Storrs, CT 06269 USA. RP Nichols, JM (reprint author), USN, Res Lab, 4555 Overlook Ave, Washington, DC 20375 USA. EM jonathan.nichols@nrl.navy.mil FU Office of Naval Research [N00014-09-WX-2-1002] FX The authors would like to acknowledge the Office of Naval Research under Contract No. N00014-09-WX-2-1002 for providing funding for this work. NR 25 TC 20 Z9 22 U1 0 U2 5 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0045-7949 J9 COMPUT STRUCT JI Comput. Struct. PD JUL PY 2011 VL 89 IS 13-14 BP 1323 EP 1332 DI 10.1016/j.compstruc.2011.03.013 PG 10 WC Computer Science, Interdisciplinary Applications; Engineering, Civil SC Computer Science; Engineering GA 781FO UT WOS:000291916200006 ER PT J AU Schmitz, J Bishop, F Patel, SJ AF Schmitz, J. Bishop, F. Patel, S. J. TI Intraocular foreign body in an F-18 jet mechanic SO EMERGENCY MEDICINE JOURNAL LA English DT Editorial Material C1 [Schmitz, J.; Bishop, F.; Patel, S. J.] USN, San Diego Med Ctr, San Diego, CA 92134 USA. RP Schmitz, J (reprint author), USN, San Diego Med Ctr, 34800 Bob Wilson Dr, San Diego, CA 92134 USA. EM joseph.schmitz@med.navy.mil NR 0 TC 0 Z9 0 U1 0 U2 1 PU B M J PUBLISHING GROUP PI LONDON PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND SN 1472-0205 J9 EMERG MED J JI Emerg. Med. J. PD JUL PY 2011 VL 28 IS 7 BP 568 EP 568 DI 10.1136/emj.2010.096917 PG 1 WC Emergency Medicine SC Emergency Medicine GA 782AK UT WOS:000291979600008 PM 20682960 ER PT J AU Sacco, LM Griffin, MTQ McNulty, R Fitzpatrick, JJ AF Sacco, Lisa M. Griffin, Mary T. Quinn McNulty, Rita Fitzpatrick, Joyce J. TI Use of the Serenity Prayer Among Adults With Type 2 Diabetes A Pilot Study SO HOLISTIC NURSING PRACTICE LA English DT Article DE prayer; research challenges; selfcare management; serenityprayer; type 2 diabetes ID ALTERNATIVE MEDICINE; INTERCESSORY PRAYER; COMPLEMENTARY; MELLITUS; TRIAL AB The incidence of type 2 diabetes is rising rapidly with significant associated morbidity and mortality. Treatment efforts are focused on control of serum blood glucose levels. It was anticipated that the use of the Serenity Prayer would assist those who need to gain control over their physiological symptoms. A pilot study of the effect of daily recitation of the Serenity Prayer for 6 weeks on serum blood glucoses in patients with uncontrolled type 2 diabetes was implemented. Thirty-six participants were enrolled in the study; there was a very high attrition rate over the course of the study. Serum blood glucose levels over the duration of the study were analyzed. At 4 to 6 weeks, time 2, there were 2 participants who had lower serum blood glucose levels, 2 had increased serum blood glucose levels, and 4 had no change. Challenges in completing this research and specific recommendations for future research are addressed. C1 [Griffin, Mary T. Quinn; McNulty, Rita; Fitzpatrick, Joyce J.] Case Western Reserve Univ, Frances Payne Bolton Sch Nursing, Cleveland, OH 44106 USA. [Sacco, Lisa M.] USN, San Diego Med Ctr, Emergency Dept, San Diego, CA USA. RP Fitzpatrick, JJ (reprint author), Case Western Reserve Univ, Frances Payne Bolton Sch Nursing, 10900 Euclid Ave, Cleveland, OH 44106 USA. EM Joyce.fitzpatrick@case.edu NR 16 TC 2 Z9 2 U1 1 U2 5 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0887-9311 J9 HOLIST NURS PRACT JI Holist. Nurs. Pract. PD JUL-AUG PY 2011 VL 25 IS 4 BP 192 EP 198 DI 10.1097/HNP.0b013e31822273a8 PG 7 WC Integrative & Complementary Medicine; Nursing SC Integrative & Complementary Medicine; Nursing GA 785CM UT WOS:000292205000004 PM 21697660 ER PT J AU Toporkov, JV Hwang, PA Sletten, MA Farquharson, G Perkovic, D Frasier, SJ AF Toporkov, Jakov V. Hwang, Paul A. Sletten, Mark A. Farquharson, Gordon Perkovic, Dragana Frasier, Stephen J. TI Surface Velocity Profiles in a Vessel's Turbulent Wake Observed by a Dual-Beam Along-Track Interferometric SAR SO IEEE GEOSCIENCE AND REMOTE SENSING LETTERS LA English DT Article DE Along-track interferometry; radar velocity measurement; sea surface; ship wake; synthetic aperture radar ID SHIP WAKES; SIMULATION; IMAGES; SPEED AB The dual-beam interferometer is an airborne instrument that combines two vertically polarized C-band along-track interferometric synthetic aperture radars (AT-InSARs) observing the surface below at different squints. The system was designed by the University of Massachusetts and saw several deployments in the early 2000s. An imagery of a small vessel with a rather pronounced wake pattern captured during one of such flights is the subject of this letter. Specifically, the interferometric phase in the turbulent wake exhibits a conspicuous banding structure that is still visible at distances more than 1 km behind the craft. The phase signatures from the fore and aft looks are combined to retrieve both longitudinal and lateral velocity components along cuts traversing the wake 400 and 750 m behind the boat. The results identify appreciable variations in the longitudinal velocity across the turbulent wake which are apparently consistent with the combined effect of the hull drag and the propeller backwash. A persistent pattern for the lateral component is also observed but is harder to interpret without the detailed knowledge of the vessel. The examples demonstrate the utility of AT-InSAR and, particularly, of a dual-beam AT-InSAR, for studies of centerline ship wakes. Readily available velocity signatures of a turbulent wake obtained with such systems can help with vessel classification tasks. C1 [Toporkov, Jakov V.; Hwang, Paul A.; Sletten, Mark A.] USN, Res Lab, Remote Sensing Div, Washington, DC 20375 USA. [Frasier, Stephen J.] Univ Massachusetts, Microwave Remote Sensing Lab, Amherst, MA 01003 USA. RP Toporkov, JV (reprint author), USN, Res Lab, Remote Sensing Div, Washington, DC 20375 USA. EM jakov.toporkov@nrl.navy.mil; paul.hwang@nrl.navy.mil; mark.sletten@nrl.navy.mil; gordon@apl.washington.edu; Perkovic@jpl.nasa.gov; frasier@ecs.umass.edu RI Frasier, Stephen/H-1536-2015; OI Frasier, Stephen/0000-0003-4287-2889; Farquharson, Gordon/0000-0002-3052-1646 FU Office of Naval Research [N00014-98-1-0612]; Naval Research Laboratory (NRL); Department of Defense FX Manuscript received September 21, 2010; accepted October 26, 2010. Date of publication January 19, 2011; date of current version June 24, 2011. This work was supported in part by the Office of Naval Research under Grant N00014-98-1-0612 to the University of Massachusetts, by the 6.1 and 6.2 Base Research Program, Naval Research Laboratory (NRL), and by the Department of Defense High Performance Computing Modernization Program under a grant of computer time at the NRL Distributed Center and was performed at the University of Massachusetts and the Naval Research Laboratory. NR 16 TC 3 Z9 3 U1 1 U2 7 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1545-598X EI 1558-0571 J9 IEEE GEOSCI REMOTE S JI IEEE Geosci. Remote Sens. Lett. PD JUL PY 2011 VL 8 IS 4 BP 602 EP 606 DI 10.1109/LGRS.2010.2096457 PG 5 WC Geochemistry & Geophysics; Engineering, Electrical & Electronic; Remote Sensing; Imaging Science & Photographic Technology SC Geochemistry & Geophysics; Engineering; Remote Sensing; Imaging Science & Photographic Technology GA 783SW UT WOS:000292105300004 ER PT J AU Andrews, JR Restaino, SR Teare, SW Sharma, YD Jang, WY Vandervelde, TE Brown, JS Reisinger, A Sundaram, M Krishna, S Lester, L AF Andrews, Jonathan R. Restaino, Sergio R. Teare, Scott W. Sharma, Yagya D. Jang, Woo-Yong Vandervelde, Thomas E. Brown, Jay S. Reisinger, Axel Sundaram, Mani Krishna, Sanjay Lester, Luke TI Comparison of Quantum Dots-in-a-Double-Well and Quantum Dots-in-a-Well Focal Plane Arrays in the Long-Wave Infrared SO IEEE TRANSACTIONS ON ELECTRON DEVICES LA English DT Article DE Infrared image sensors; quantum dots (QDs); quantum wells (QWs); radiometry ID PHOTODETECTORS; WAVELENGTH AB Our previous research has reported on the development of the first generation of quantum dots-in-a-well (DWELL) focal plane arrays (FPAs), which are based on InAs quantum dots (QDs) embedded in an InGaAs well having GaAs barriers, which have demonstrated spectral tunability via an externally applied bias voltage. More recently, technologies in DWELL devices have been further advanced by embedding InAs QDs in InGaAs and GaAs double wells with AlGaAs barriers, leading to a less strained InAs/InGaAs/GaAs/AlGaAs heterostructure. These lower strain quantum dots-in-a-double-well devices exhibit lower dark current than the previous generation DWELL devices while still demonstrating spectral tunability. This paper compares two different configurations of double DWELL (DDWELL) FPAs to a previous generation DWELL detector and to a commercially available quantum well infrared photodetector (QWIP). All four devices are 320 x 256 pixel FPAs that have been fabricated and hybridized with an Indigo 9705 read-out integrated circuit. Radiometric characterization, average array responsivity, array uniformity and measured noise equivalent temperature difference for all four devices is computed and compared at 60 K. Overall, the DDWELL devices had lower noise equivalent temperature difference and higher uniformity than the first-generation DWELL devices, although the commercially available QWIP has demonstrated the best performance. C1 [Andrews, Jonathan R.; Restaino, Sergio R.] USN, Res Lab, Remote Sensing Div, Albuquerque, NM 87117 USA. [Teare, Scott W.] New Mexico Inst Min & Technol, Dept Elect Engn, Socorro, NM 87801 USA. [Sharma, Yagya D.; Jang, Woo-Yong; Brown, Jay S.; Krishna, Sanjay; Lester, Luke] Univ New Mexico, Ctr High Technol Mat, Albuquerque, NM 87106 USA. [Vandervelde, Thomas E.] Tufts Univ, Dept Elect & Comp Engn, Renewable Energy & Appl Phys Lab, Medford, MA 02155 USA. [Reisinger, Axel; Sundaram, Mani] QmagiQ LLC, Nashua, NH 03063 USA. RP Andrews, JR (reprint author), USN, Res Lab, Remote Sensing Div, Albuquerque, NM 87117 USA. EM jonathan.andrews@kirtland.af.mil; sergio.restaino@kirtland.af.mil; teare@ee.nmt.edu; skrishna@chtm.unm.edu; tvanderv@ece.tufts.edu; areisinger@qmaiq.com RI Krishna, Sanjay /C-5766-2009; Vandervelde, Tom/I-3317-2013 FU Airforce Research Laboratory [FA9453-07-C-0171]; Los Alamos National Laboratory; National Science Foundation; Korea Research Institute of Standards and Science-Global Research Laboratory Program FX Manuscript received September 29, 2010; revised March 15, 2011; accepted March 20, 2011. Date of publication May 2, 2011; date of current version June 22, 2011. This work was supported in part by the Airforce Research Laboratory under Contract FA9453-07-C-0171, by Los Alamos National Laboratory, by the National Science Foundation, and by Korea Research Institute of Standards and Science-Global Research Laboratory Program. The review of this paper was arranged by Editor J. R. Tower. NR 14 TC 7 Z9 7 U1 1 U2 9 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0018-9383 J9 IEEE T ELECTRON DEV JI IEEE Trans. Electron Devices PD JUL PY 2011 VL 58 IS 7 BP 2022 EP 2027 DI 10.1109/TED.2011.2140374 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA 781SD UT WOS:000291952900026 ER PT J AU Blunt, S Mokole, E AF Blunt, Shannon Mokole, Eric TI Special Section on Waveform Diversity from the Fifth International Waveform Diversity and Design Conference, Niagara Falls, Canada SO IET RADAR SONAR AND NAVIGATION LA English DT Editorial Material C1 [Blunt, Shannon] Univ Kansas, Dept Elect Engn & Comp Sci, Lawrence, KS 66045 USA. [Blunt, Shannon] Radar Syst Lab, Lawrence, KS USA. [Mokole, Eric] Naval Intelligence Support Ctr, Elect Warfare Div, Washington, DC USA. [Mokole, Eric] USN, Res Lab, Div Radar, Washington, DC USA. RP Blunt, S (reprint author), Univ Kansas, Dept Elect Engn & Comp Sci, Lawrence, KS 66045 USA. NR 0 TC 1 Z9 1 U1 0 U2 2 PU INST ENGINEERING TECHNOLOGY-IET PI HERTFORD PA MICHAEL FARADAY HOUSE SIX HILLS WAY STEVENAGE, HERTFORD SG1 2AY, ENGLAND SN 1751-8784 J9 IET RADAR SONAR NAV JI IET Radar Sonar Navig. PD JUL PY 2011 VL 5 IS 6 BP 671 EP 673 DI 10.1049/iet-rsn.2011.9052 PG 3 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA 784VX UT WOS:000292187500009 ER PT J AU Baylis, C Wang, L Moldovan, M Martin, J Miller, H Cohen, L de Graaf, J AF Baylis, C. Wang, L. Moldovan, M. Martin, J. Miller, H. Cohen, L. de Graaf, J. TI Designing transmitters for spectral conformity: power amplifier design issues and strategies SO IET RADAR SONAR AND NAVIGATION LA English DT Article; Proceedings Paper CT 5th International Waveform Diversity and Design Conference (WDD) CY AUG 03-10, 2010 CL Niagara Falls, CANADA AB Spectral constraints placed on radar systems by regulatory agencies require the design of highly linear amplifiers. Spectral spreading in power amplifiers is a result of transistors operated in the non-linear regime to optimise efficiency. Various methods are employed by power amplifier designers to maximise both linearity and efficiency. The methods of predistortion, feedforward, envelope tracking, Doherty and 'linear amplification using non-linear components' are discussed in this article. Trade-offs and challenges inherent in these design approaches are surveyed. C1 [Baylis, C.; Wang, L.; Moldovan, M.; Martin, J.; Miller, H.] Baylor Univ, Wireless & Microwave Circuits & Syst Program, Dept Elect & Comp Engn, Waco, TX 76798 USA. [Cohen, L.; de Graaf, J.] USN, Res Lab, Div Radar, Washington, DC 20375 USA. RP Baylis, C (reprint author), Baylor Univ, Wireless & Microwave Circuits & Syst Program, Dept Elect & Comp Engn, 1 Bear Pl 97356, Waco, TX 76798 USA. EM Charles_Baylis@baylor.edu NR 15 TC 14 Z9 15 U1 0 U2 1 PU INST ENGINEERING TECHNOLOGY-IET PI HERTFORD PA MICHAEL FARADAY HOUSE SIX HILLS WAY STEVENAGE, HERTFORD SG1 2AY, ENGLAND SN 1751-8784 J9 IET RADAR SONAR NAV JI IET Radar Sonar Navig. PD JUL PY 2011 VL 5 IS 6 BP 681 EP 685 DI 10.1049/iet-rsn.2010.0334 PG 5 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA 784VX UT WOS:000292187500011 ER PT J AU Stewart, AE Stalp, JT Futerman, C Vaughan, WC AF Stewart, Alexander E. Stalp, John T. Futerman, Cheryl Vaughan, Winston C. TI Variability of radiation exposure with in-office sinus computed tomography examinations SO INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY LA English DT Article; Proceedings Paper CT 56th Annual Fall Scientific Meeting of the American-Rhinologic-Society (ARS) CY SEP 25-28, 2010 CL Boston, MA SP Amer Rhinol Soc (ARS) DE cancer; computed tomography; CT; endoscopic sinus surgery; image guidance; radiation; sinusitis ID CANCER-RISKS; CT AB Background: An increasing number of patients seeking care by an otolaryngologist are undergoing computed tomography (CT) examinations via in-office CT scanners. Many otolaryngologists and patients are not fully aware of the radiation dosages and the associated risks. A recent study of common CT examinations demonstrated significant variability in radiation dosages for similar studies. Despite the relatively low doses associated with sinus scans, widely publicized studies and events have generated a renewal of physician, public, and regulatory agency awareness and concern regarding medical radiation exposure. Methods: Phantom measurements and/or radiation dosage reports from CT scanners utilized by a large otolaryngology group in California were reviewed and compared. Different types of CT scanners from multiple manufacturers were included. Results: There was nearly a 10-fold difference (0.15-1.45 mSv) in radiation between scans obtained from in-office, hospital-based, and outpatient imaging facility CT scanners. Conclusion: Significant relative variability can exist in radiation dosages associated with routine sinus CT scans obtained in different locations. There is a need for increased awareness and understanding among otolaryngologists and their patients regarding medical radiation exposure. All otolaryngologists should constantly consider the principle of "as low as reasonably achievable" (ALARA). Shielding, pediatric protocols, and other dosage reduction measures should be utilized whenever possible. (C) 2011 ARS-AAOA, LLC. C1 [Stewart, Alexander E.] USN, San Diego Med Ctr, Dept Otolaryngol Head & Neck Surg, San Diego, CA 92134 USA. [Stewart, Alexander E.; Vaughan, Winston C.] Calif Sinus Ctr, Atherton, CA USA. [Stalp, John T.] ABR Certified Radiol Physicist, Fairfax, VA USA. [Futerman, Cheryl] Palo Alto Imaging, Palo Alto, CA USA. RP Stewart, AE (reprint author), USN, San Diego Med Ctr, Dept Otolaryngol Head & Neck Surg, 34800 Bob Wilson Dr, San Diego, CA 92134 USA. EM alexander.stewart@med.navy.mil NR 24 TC 3 Z9 3 U1 0 U2 0 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 2042-6976 J9 INT FORUM ALLERGY RH JI Int. Forum Allergy Rhinol. PD JUL-AUG PY 2011 VL 1 IS 4 BP 313 EP 318 DI 10.1002/alr.20049 PG 6 WC Otorhinolaryngology SC Otorhinolaryngology GA 007XS UT WOS:000308922300015 PM 22287438 ER PT J AU Ruang-areerate, T Jeamwattanalert, P Rodkvamtook, W Richards, AL Sunyakumthorn, P Gaywee, J AF Ruang-areerate, Toon Jeamwattanalert, Pimmada Rodkvamtook, Wuttikorn Richards, Allen L. Sunyakumthorn, Piyanate Gaywee, Jariyanart TI Genotype Diversity and Distribution of Orientia tsutsugamushi Causing Scrub Typhus in Thailand SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article ID RICKETTSIA-TSUTSUGAMUSHI; INDIRECT IMMUNOFLUORESCENCE; PHYLOGENETIC ANALYSIS; SEQUENCE HOMOLOGIES; ANTIGENIC VARIANTS; IDENTIFICATION; STRAINS; GENES; CLASSIFICATION; TROMBICULIDAE AB Scrub typhus, caused by antigenically disparate isolates of Orientia tsutsugamushi, is a widely distributed mite-borne human disease in the Asia Pacific region. Information regarding the heterogeneity of the immunodominant 56-kDa type-specific antigen (TSA) gene is crucial for the design and evaluation of scrub typhus-specific diagnostic assays and vaccines. Using indirect immunofluorescence assays (IFA) and PCR assays, O. tsutsugamushi was detected samples from rodents and patients with fever of unknown origin obtained from six provinces of Thailand during 2004 to 2007. Sequences were determined for a fragment of the 56-kDa TSA gene, and the relationship between these sequences and those previously determined were assessed. The phylogenetic analyses of partial 56-kDa TSA gene sequences demonstrated wide diversity and distribution of O. tsutsugamushi genotypes in Thailand. Furthermore, the genetic diversity grouped the scrub typhus agents into two commonly and five infrequently found genotypes within six provinces of Thailand. The two most commonly found genotypes of O. tsutsugamushi described in this study do not associate with the prototype strains that are widely used for the design and evaluation of diagnostic assays and vaccine candidates. Thus, these new genotypes should be considered for future scrub typhus assay and vaccine development. C1 [Ruang-areerate, Toon] Armed Forces Res Inst Med Sci, Epidemiol Sect, Div Res, Bangkok 10400, Thailand. [Jeamwattanalert, Pimmada] Armed Forces Res Inst Med Sci, Dept Enter Dis, Bangkok 10400, Thailand. [Richards, Allen L.] USN, Viral & Rickettsial Dis Dept, Med Res Ctr, Silver Spring, MD 20910 USA. [Sunyakumthorn, Piyanate] Louisiana State Univ, Sch Vet Med, Dept Pathobiol Sci, Baton Rouge, LA 70803 USA. RP Ruang-areerate, T (reprint author), Armed Forces Res Inst Med Sci, Epidemiol Sect, Div Res, 315-6 Rajvithi Rd, Bangkok 10400, Thailand. EM toonr@afrims.go.th RI Valle, Ruben/A-7512-2013 FU Thanphuying Viraya Chavakul Foundation for Medical Armed Forces; Thailand Tropical Diseases Research Funding Program [T-2]; Global Emerging Infections Surveillance and Response System, a Division of the Armed Forces Health Surveillance Center FX This work was supported by a Thanphuying Viraya Chavakul Foundation for Medical Armed Forces Research grant (2008 to 2009) and the Thailand Tropical Diseases Research Funding Program (T-2). Part of this work (by A. L. R.) was supported by the Global Emerging Infections Surveillance and Response System, a Division of the Armed Forces Health Surveillance Center. NR 31 TC 12 Z9 13 U1 0 U2 2 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD JUL PY 2011 VL 49 IS 7 BP 2584 EP 2589 DI 10.1128/JCM.00355-11 PG 6 WC Microbiology SC Microbiology GA 786BC UT WOS:000292276200032 PM 21593255 ER PT J AU Dean, J Harrison, A Lass, RN Macker, J Millar, D Taylor, I AF Dean, Justin Harrison, Andrew Lass, Robert N. Macker, Joe Millar, David Taylor, Ian TI Client/server messaging protocols in serverless environments SO JOURNAL OF NETWORK AND COMPUTER APPLICATIONS LA English DT Article DE XMPP; Serverless chat; WS-Notification; SLP; JmDNS; Peer-to-Peer; Multicast; NORM AB In this paper we discuss the adaptation of TCP transport-oriented client-server messaging protocols to many-to-many peer-to-peer networking environments more suitable for deployment in dynamic wireless networks capable of multicast forwarding. We describe four main issues in adapting such protocols: exposing a network server for receiving TCP session data; the creation of server-side semantic proxies to process the messages and adapt to a serverless environment; service discovery to enable the discovery of necessary services on the network and to maintain the network state; and finally support for multicast interfaces for the transportation of messages amongst peers. We show that our system, called GUMP, can be used to support such protocol adaptations and to illustrate we use GUMP to implement an XMPP proxy allowing existing off-the-shelf XMPP client software to dynamically create and operate multi-user chat sessions in a serverless network environment. We then present two sets of results that show how appropriate discovery systems and transport protocols can dramatically increase the success of protocols, such as XMPP, within a mobile wireless networked environment. Specifically, we first demonstrate that a GUMP supported discovery system, INDI, can significantly increase the success rates and decrease latency of discovering services through profiles, caching and retrying schemes. Second, we show that success rates for XMPP transmission of messages can be vastly improved through the use of multicast as apposed to TCP within the mobile environment. These two factors provide strong empirical support for the justification of GUMP in its ability to adapt between a client-server and serverless world. (C) 2011 Elsevier Ltd. All rights reserved. C1 [Harrison, Andrew; Taylor, Ian] Cardiff Univ, Sch Comp Sci, Cardiff, S Glam, Wales. [Lass, Robert N.; Millar, David] Drexel Univ, Dept Comp Sci, Philadelphia, PA USA. [Dean, Justin; Macker, Joe] Naval Res Lab, Washington, DC USA. RP Taylor, I (reprint author), Cardiff Univ, Sch Comp Sci, Cardiff, S Glam, Wales. EM Ian.J.Taylor@cs.cardiff.ac.uk OI Taylor, Ian/0000-0001-5040-0772 FU Office of Naval Research FX GUMP has been developed by the Networks and Communication Systems Branch of the IT Division at NAL. On-going modifications and experiments with the core system have been funded by the Office of Naval Research Service-Oriented Networking Over MANET (SONOMA) project. We thank Brian Adamson for his guidance and input into the NORM protocol and its integration and David Talmage for helping stress test and debug GUMP during its development phase. NR 32 TC 0 Z9 0 U1 1 U2 6 PU ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD PI LONDON PA 24-28 OVAL RD, LONDON NW1 7DX, ENGLAND SN 1084-8045 J9 J NETW COMPUT APPL JI J. Netw. Comput. Appl. PD JUL PY 2011 VL 34 IS 4 SI SI BP 1366 EP 1379 DI 10.1016/j.jnca.2011.03.021 PG 14 WC Computer Science, Hardware & Architecture; Computer Science, Interdisciplinary Applications; Computer Science, Software Engineering SC Computer Science GA 780IC UT WOS:000291846700031 ER PT J AU Petilon, J Roth, J Hardenbrook, M AF Petilon, Julio Roth, Jonathan Hardenbrook, Mitchell TI Results of Lumbar Total Disc Arthroplasty in Military Personnel SO JOURNAL OF SPINAL DISORDERS & TECHNIQUES LA English DT Article DE total disc arthroplasty; artificial disc; lumbar spine; degenerative disc disease; military ID CHARITE(TM) ARTIFICIAL DISC; CLINICAL-OUTCOMES; FOLLOW-UP; REPLACEMENT AB Study Design: Evaluation of lumbar total disc arthroplasty (TDA) in military patients. Objective: To evaluate the clinical and radiographic outcomes of US military personnel who have undergone TDA for degenerative disc disease and to assess the retention versus discharge rate after undergoing this procedure. Summary of Background Data: TDA was developed as an alternative to arthrodesis for the surgical management of degenerative disc disease with the goal of preserving motion and reducing adjacent segment disease. However, the indications and optimal candidates for this procedure are uncertain. Military members must maintain a certain level of physical fitness and be capable of meeting the demands of hazardous environments. This study reviews results of TDA performed on active duty military members. Methods: The surgery schedules from 2005 to 2008 were reviewed to identify military members who underwent single-level or 2-level TDA for degenerative disc disease after failing at least 6 months of conservative management. All patients had a minimum of 2-year follow-up. Preoperative and postoperative clinical assessments were completed using the Oswestry Disability Index (ODI) questionnaire and the numeric rating scale (NRS). Radiographs were evaluated to determine range of motion, height, and disc position at the operated levels. The retention rate of the patients in the military was also recorded. Statistical analysis of the data was carried out with significance assumed at the P < 0.05 level. Results: Thirty-eight patients, implanted with a total of 56 discs, met the criteria for retrospective analysis. Twenty patients had single-level and 18 had 2-level TDA. Mean age was 35 (23 to 56 y) years. Mean follow-up was 28 months. The overall mean preoperative ODI and NRS of 53.6 and 7.3, significantly improved postoperatively to 27.7 and 3.3, respectively (P < 0.001). There was no difference in the postoperative ODI (P = 0.19) or NRS (P = 0.18) when comparing single-level and 2-level TDA. Clinical success was achieved in 79% of patients. Mean range of motion was 6.5 degrees and the mean disc height increased by 69%. Sixty-eight percent of patients returned to full active duty. Conclusions: This study showed clinical success approaching 80% in military patients who underwent lumbar TDA. Furthermore, close to 70% were able to return to their positions within the military. TDA, while more closely reapproximating the normal biomechanics of the spine, may provide patients with an improved alternative to spinal arthrodesis for degenerative disc disease. C1 [Petilon, Julio; Roth, Jonathan] USN, Dept Orthopaed Surg, Bone & Joint Inst, Naval Med Ctr Portsmouth, Portsmouth, VA 23708 USA. [Hardenbrook, Mitchell] Boston Spine Grp, Newton, MA USA. RP Petilon, J (reprint author), USN, Dept Orthopaed Surg, Bone & Joint Inst, Naval Med Ctr Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA 23708 USA. EM juliopetilon@hotmail.com FU Navy Bureau of Medicine and Surgery, Washington, DC [P06-037] FX The Chief, Navy Bureau of Medicine and Surgery, Washington, DC, Clinical Investigation Program sponsored this study (P06-037). NR 18 TC 2 Z9 2 U1 4 U2 4 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 1536-0652 J9 J SPINAL DISORD TECH JI J. Spinal Disord. Tech. PD JUL PY 2011 VL 24 IS 5 BP 297 EP 301 DI 10.1097/BSD.0b013e3181fb3e2a PG 5 WC Clinical Neurology; Orthopedics SC Neurosciences & Neurology; Orthopedics GA 786EL UT WOS:000292286000004 PM 20975590 ER PT J AU Mohr, SB Garland, CF Gorham, ED Grant, WB Garland, FC AF Mohr, Sharif B. Garland, Cedric F. Gorham, Edward D. Grant, William B. Garland, Frank C. TI Ultraviolet B and Incidence Rates of Leukemia Worldwide SO AMERICAN JOURNAL OF PREVENTIVE MEDICINE LA English DT Article ID 1-ALPHA,25-DIHYDROXYVITAMIN D-3-26,23-LACTONE ANALOGS; GROWTH-FACTOR-I; VITAMIN-D; MYELOID-LEUKEMIA; CANCER MORTALITY; COLON CANCER; CHILDHOOD LEUKEMIA; OVARIAN-CANCER; RETINOIC ACID; UNITED-STATES AB Background: Recent research has suggested a relationship between vitamin D deficiency and risk of leukemia. Purpose: Using data from the UN cancer database, GLOBOCAN, this study will determine whether a relationship exists for latitude and ultraviolet B (UVB) irradiance with incidence rates of leukemia in 175 countries. Methods: Multiple regression was used to analyze the independent association between UVB and age-adjusted incidence rates of leukemia in 139 countries in 2002. This study controlled for dietary data on intake of energy from animal sources and per capita healthcare expenditures. The analyses were performed in 2009. Results: People residing in the highest-latitude countries had the highest rates of leukemia in both men (R(2)=0.34, p<0.0001) and women (R(2)=0.24, p<0.0001). In men, UVB was independently inversely associated with leukemia incidence rates (p <= 0.001), whereas animal energy consumption (p=0.02) and per capita healthcare expenditures (p <= 0.0001) were independently positively associated (R(2) for model=0.61, p <= 0.0001). In women, UVB adjusted for cloud cover was independently inversely associated with leukemia incidence rates (p <= 0.01), whereas animal energy consumption (p <= 0.05) and per capita healthcare expenditures (p=0.0002) were independently positively associated (R(2) for model=0.51, p<0.0001). Conclusions: Countries with low UVB had higher age-adjusted incidence rates of leukemia. This suggests the possibility that low serum 25-hydroxyvitamin D status, because of lower levels of UVB, somehow might predict the development of leukemia. (Am J Prev Med 2011; 41(1): 68-74) (C) 2011 Published by Elsevier Inc. on behalf of American Journal of Preventive Medicine. C1 [Mohr, Sharif B.; Garland, Cedric F.; Gorham, Edward D.; Garland, Frank C.] Univ Calif San Diego, Dept Family & Prevent Med, Div Epidemiol, La Jolla, CA 92093 USA. [Mohr, Sharif B.; Garland, Cedric F.; Gorham, Edward D.] USN, Hlth Res Ctr, Dept Hlth Sci & Epidemiol, San Diego, CA 92152 USA. [Garland, Frank C.] USN, Hlth Res Ctr, Off Tech Director, San Diego, CA 92152 USA. [Grant, William B.] Sunlight Nutr & Hlth Res Ctr, San Francisco, CA USA. RP Garland, CF (reprint author), Univ Calif San Diego, Dept Family & Prevent Med, Div Epidemiol, 9500 Gilman Dr, La Jolla, CA 92093 USA. EM cgarland@ucsd.edu RI Grant, William/B-8311-2009 OI Grant, William/0000-0002-1439-3285 FU Hershey Medical Center, Hershey PA through the Department of the Navy, Bureau of Medicine and Surgery at the Naval Health Research Center (San Diego CA) [60126] FX This research was supported by a Congressional allocation to the Penn State Cancer Institute of the Hershey Medical Center, Hershey PA, through the Department of the Navy, Bureau of Medicine and Surgery, under Work Unit No. 60126 at the Naval Health Research Center (San Diego CA). The views expressed in this report are those of the authors and do not represent an official position of the Department of the Navy, Department of Defense, or the U.S. Government. NR 50 TC 8 Z9 8 U1 0 U2 7 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 0749-3797 J9 AM J PREV MED JI Am. J. Prev. Med. PD JUL PY 2011 VL 41 IS 1 BP 68 EP 74 DI 10.1016/j.amepre.2011.04.003 PG 7 WC Public, Environmental & Occupational Health; Medicine, General & Internal SC Public, Environmental & Occupational Health; General & Internal Medicine GA 775OC UT WOS:000291468700011 PM 21665065 ER PT J AU Behr, BB Cenko, AT Hajian, AR McMillan, RS Murison, M Meade, J Hindsley, R AF Behr, Bradford B. Cenko, Andrew T. Hajian, Arsen R. McMillan, Robert S. Murison, Marc Meade, Jeff Hindsley, Robert TI STELLAR ASTROPHYSICS WITH A DISPERSED FOURIER TRANSFORM SPECTROGRAPH. II. ORBITS OF DOUBLE-LINED SPECTROSCOPIC BINARIES SO ASTRONOMICAL JOURNAL LA English DT Article DE binaries: spectroscopic; instrumentation: spectrographs; techniques: radial velocities ID PHASES DIFFERENTIAL ASTROMETRY; PRECISION RADIAL-VELOCITIES; ECLIPSING BINARIES; IOTA-PEGASI; KAPPA-PEGASI; V-1143 CYGNI; ETA-VIRGINIS; STAR SYSTEM; 12 BOOTIS; TRIPLE AB We present orbital parameters for six double-lined spectroscopic binaries (iota Pegasi, omega Draconis, 12 Bootis, V1143 Cygni, beta Aurigae, and Mizar A) and two double-lined triple star systems (kappa Pegasi and eta Virginis). The orbital fits are based upon high-precision radial velocity (RV) observations made with a dispersed Fourier Transform Spectrograph, or dFTS, a new instrument that combines interferometric and dispersive elements. For some of the double-lined binaries with known inclination angles, the quality of our RV data permits us to determine the masses M-1 and M-2 of the stellar components with relative errors as small as 0.2%. C1 [Behr, Bradford B.; Cenko, Andrew T.; Hajian, Arsen R.; Meade, Jeff] Univ Waterloo, Dept Syst Design Engn, Waterloo, ON N2L 3G1, Canada. [Behr, Bradford B.] Eureka Sci, Oakland, CA 94602 USA. [Behr, Bradford B.; Hajian, Arsen R.; Meade, Jeff] Arjae Spectral Enterprises, Toronto, ON M5V 3B1, Canada. [McMillan, Robert S.] Univ Arizona, Lunar & Planetary Lab, Tucson, AZ 85721 USA. [Murison, Marc] USN Observ, Flagstaff Stn, Flagstaff, AZ 86001 USA. [Hindsley, Robert] USN, Res Lab, Remote Sensing Div, Washington, DC 20375 USA. RP Behr, BB (reprint author), Univ Waterloo, Dept Syst Design Engn, Waterloo, ON N2L 3G1, Canada. FU ARH's NSERC FX This research was funded in part by ARH's NSERC Discovery Grant. NR 41 TC 1 Z9 1 U1 0 U2 4 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-6256 J9 ASTRON J JI Astron. J. PD JUL PY 2011 VL 142 IS 1 AR 6 DI 10.1088/0004-6256/142/1/6 PG 11 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 777AE UT WOS:000291584200006 ER PT J AU Boyd, MR Winters, JG Henry, TJ Jao, WC Finch, CT Subasavage, JP Hambly, NC AF Boyd, Mark R. Winters, Jennifer G. Henry, Todd J. Jao, Wei-Chun Finch, Charlie T. Subasavage, John P. Hambly, Nigel C. TI THE SOLAR NEIGHBORHOOD. XXV. DISCOVERY OF NEW PROPER MOTION STARS WITH 0 ''.40 yr(-1) > mu >= 0 ''.18 yr(-1) BETWEEN DECLINATIONS -47 degrees AND 00 degrees SO ASTRONOMICAL JOURNAL LA English DT Article DE astrometry; solar neighborhood; stars: distances; stars: low-mass; stars: statistics; surveys ID DIGITIZED SKY SURVEY; WHITE-DWARF SYSTEMS; NEARBY STARS; SOUTHERN SKY; SAMPLE; PROGRAM; CATALOG; -90-DEGREES; UCAC3 AB We present 2817 new southern proper motion systems with 0 ''.40 yr(-1) > mu >= 0 ''.18 yr(-1) and declination between -47 degrees and 00 degrees. This is a continuation of the SuperCOSMOS-RECONS (SCR) proper motion searches of the southern sky. We use the same photometric relations as previous searches to provide distance estimates based on the assumption that the objects are single main-sequence stars. We find 79 new red dwarf systems predicted to be within 25 pc, including a few new components of previously known systems. Two systems-SCR 1731-2452 at 9.5 pc and SCR 1746-3214 at 9.9 pc-are anticipated to be within 10 pc. We also find 23 new white dwarf (WD) candidates with distance estimates of 15-66 pc, as well as 360 new red subdwarf candidates. With this search, we complete the SCR sweep of the southern sky for stars with mu >= 0 ''.18 yr(-1) and R-59F <= 16.5, resulting in a total of 5042 objects in 4724 previously unreported proper motion systems. Here we provide selected comprehensive lists from our SCR proper motion search to date, including 152 red dwarf systems estimated to be within 25 pc (9 within 10 pc), 46 WDs (10 within 25 pc), and 598 subdwarf candidates. The results of this search suggest that there are more nearby systems to be found at fainter magnitudes and lower proper motion limits than those probed so far. C1 [Boyd, Mark R.] Georgia Inst Technol, Dept Math, Atlanta, GA 30332 USA. [Winters, Jennifer G.; Henry, Todd J.; Jao, Wei-Chun] Georgia Inst Technol, Dept Phys & Astron, Atlanta, GA 30332 USA. [Finch, Charlie T.] USN Observ, Washington, DC 20392 USA. [Subasavage, John P.] Cerro Tololo Interamer Observ, La Serena, Chile. [Hambly, Nigel C.] Univ Edinburgh, Royal Observ, Inst Astron, Scottish Univ Phys Alliance, Edinburgh EH9 3HJ, Midlothian, Scotland. RP Boyd, MR (reprint author), Georgia Inst Technol, Dept Math, Atlanta, GA 30332 USA. EM boyd@chara.gsu.edu; winters@chara.gsu.edu; thenry@chara.gsu.edu; jao@chara.gsu.edu; finch@usno.navy.mil; jsubasavage@ctio.noao.edu; nch@roe.ac.uk FU National Science Foundation [AST 09-08402]; NASA [NNX08BA95G]; UK Particle Physics and Astronomy Research Council FX The RECONS effort is supported by the National Science Foundation through grant AST 09-08402. This effort has also been supported by NASA grant NNX08BA95G. We thank GSU Honors Students Gregory Brooks, Daryl Giuliano, Skyler Green, and Scott Stinson, each of whom assisted in the blinking process. Funding for the SuperCOSMOS Sky Survey was provided by the UK Particle Physics and Astronomy Research Council. N.C.H. thanks colleagues in the Wide Field Astronomy Unit at Edinburgh for their work in making the SSS possible; particular thanks go to Mike Read, Sue Tritton, and Harvey MacGillivray. This research has made use of results from the SAO/NASA Astrophysics Data System Bibliographic Services, the SIMBAD and VizieR databases operated at CDS, Strasbourg, France, and the Two Micron All Sky Survey, which is a joint project of the University of Massachusetts and the Infrared Processing and Analysis Center, funded by NASA and NSF. NR 36 TC 11 Z9 11 U1 0 U2 3 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-6256 EI 1538-3881 J9 ASTRON J JI Astron. J. PD JUL PY 2011 VL 142 IS 1 AR 10 DI 10.1088/0004-6256/142/1/10 PG 16 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 777AE UT WOS:000291584200010 ER PT J AU Girard, TM van Altena, WF Zacharias, N Vieira, K Casetti-Dinescu, DI Castillo, D Herrera, D Lee, YS Beers, TC Monet, DG Lopez, CE AF Girard, Terrence M. van Altena, William F. Zacharias, Norbert Vieira, Katherine Casetti-Dinescu, Dana I. Castillo, Danilo Herrera, David Lee, Young Sun Beers, Timothy C. Monet, David G. Lopez, Carlos E. TI THE SOUTHERN PROPER MOTION PROGRAM. IV. THE SPM4 CATALOG SO ASTRONOMICAL JOURNAL LA English DT Article DE astrometry; catalogs ID SKY SURVEY 2MASS; GLOBULAR-CLUSTERS; SPACE VELOCITIES; GALACTIC CONSTANT; THICK DISK; ASTROMETRY; RAVE; POLE AB We present the fourth installment of the Yale/San Juan Southern Proper Motion Catalog, SPM4. The SPM4 contains absolute proper motions, celestial coordinates, and B, V photometry for over 103 million stars and galaxies between the south celestial pole and -20 degrees declination. The catalog is roughly complete to V = 17.5 and is based on photographic and CCD observations taken with the Yale Southern Observatory's double astrograph at Cesco Observatory in El Leoncito, Argentina. The proper-motion precision, for well-measured stars, is estimated to be 2-3 mas yr(-1), depending on the type of second-epoch material. At the bright end, proper motions are on the International Celestial Reference System by way of Hipparcos Catalog stars, while the faint end is anchored to the inertial system using external galaxies. Systematic uncertainties in the absolute proper motions are on the order of 1 mas yr(-1). C1 [Girard, Terrence M.; van Altena, William F.; Vieira, Katherine; Casetti-Dinescu, Dana I.] Yale Univ, Dept Astron, New Haven, CT 06520 USA. [Zacharias, Norbert] USN Observ, Washington, DC 20392 USA. [Castillo, Danilo] Dept Sci Operat, San Pedro De Atacama, II Region Alma, Chile. [Herrera, David] Natl Opt Astron Observ, Tucson, AZ 85719 USA. [Lee, Young Sun; Beers, Timothy C.] Michigan State Univ, Dept Phys & Astron, E Lansing, MI 48824 USA. [Lee, Young Sun; Beers, Timothy C.] Michigan State Univ, Joint Inst Nucl Astrophys, E Lansing, MI 48824 USA. [Monet, David G.] USN Observ, Flagstaff Stn, Flagstaff, AZ 86002 USA. [Lopez, Carlos E.] Univ Nacl San Juan, Observ Astron Felix Aguilar, RA-5413 Chimbas, San Juan, Argentina. [Lopez, Carlos E.] Yale So Observ, RA-5413 Chimbas, San Juan, Argentina. RP Girard, TM (reprint author), Yale Univ, Dept Astron, New Haven, CT 06520 USA. EM terry.girard@yale.edu; william.vanaltena@yale.edu; nz@usno.navy.mil; kvieira@cida.ve; dana.casetti@yale.edu; daniloeros@hotmail.com; dherrera@noao.edu; lee@pa.msu.edu; beers@pa.msu.edu; dgm@nofs.navy.mil; cel_2018@yahoo.com.ar FU National Science Foundation [AST04-0908996]; NSF [PHY 02-16783, PHY 08-22648]; Ford Foundation; NASA; Argentine CONICET; Yale University FX We are grateful to the National Science Foundation for their substantial support in the form of a series of grants spanning more than four decades, the most recent being grant AST04-0908996; the University of San Juan for extensive logistical and personnel support throughout the course of the survey; the Argentine CONICET for funding some of the instrumentation; and Yale University for critical financial support during the completion of the SPM program. Also, we are thankful for partial support from the NSF under grants PHY 02-16783 and PHY 08-22648 (Physics Frontier Center/Joint Institute for Nuclear Astrophysics). The SPM program would not have begun were it not for an initial grant from the Ford Foundation, which we also gratefully acknowledge. Finally, we are indebted to our observers who provided the raw material upon which this catalog is based.; This publication makes use of data products from the Two Micron All Sky Survey, which is a joint project of the University of Massachusetts and the Infrared Processing and Analysis Center/California Institute of Technology, funded by NASA and the NSF. NR 42 TC 64 Z9 64 U1 0 U2 3 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-6256 J9 ASTRON J JI Astron. J. PD JUL PY 2011 VL 142 IS 1 AR 15 DI 10.1088/0004-6256/142/1/15 PG 12 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 777AE UT WOS:000291584200015 ER PT J AU Lewis, KT Sambruna, RM Angelakis, E Eracleous, M Cheung, CC Kadler, M AF Lewis, Karen T. Sambruna, Rita M. Angelakis, Emmanouil Eracleous, Michael Cheung, Chi C. Kadler, Matthias TI MULTI-WAVELENGTH OBSERVATIONS OF A SAMPLE OF INTERMEDIATE-LUMINOSITY RADIO-LOUD ACTIVE GALAXIES SO ASTRONOMICAL JOURNAL LA English DT Article DE galaxies: active; galaxies: nuclei; radio continuum: galaxies; X-rays: galaxies ID DIGITAL-SKY-SURVEY; GALACTIC NUCLEI; X-RAY; SEYFERT-GALAXIES; DUST; VARIABILITY; REFLECTION; RADIATION; EMISSION; SPECTRUM AB We present the results from exploratory (12-23 ks) XMM-Newton observations of six optically selected, radio-loud active galactic nuclei (AGNs), together with new radio data and a reanalysis of their archival SDSS spectra. The sources were selected in an effort to expand the current sample of radio-loud AGNs suitable for detailed X-ray spectroscopy studies. The sample includes three broad-line and three narrow-line sources, with X-ray luminosities of the order of L2-10 keV similar to 10(43) erg s(-1). The EPIC spectra of the broad-lined sources can be described by single power laws with photon indices Gamma similar to 1.6 and little to negligible absorption (N-H less than or similar to 10(21) cm(-2)); on the contrary, significant absorption is detected in the narrow-lined objects, N-H similar to 10(23) cm(-2), one of which displays a prominent (equivalent width similar to 2 keV) Fe K alpha emission line. Studying their location in several luminosity-luminosity diagrams for radio-loud AGNs, we find that the sources fall at the lower end of the distribution for bright, classical radio-loud AGNs and close to LINER-like sources. As such, and as indicated by the ratios of their optical emission lines, we conclude that the sources of our sample fall on the border between radiatively efficient and inefficient accretion flows. Future deeper studies of these targets at X-rays and longer wavelengths will expand our understanding of the central engines of radio-loud AGNs at a critical transition region. C1 [Lewis, Karen T.] Coll Wooster, Dept Phys, Wooster, OH 44691 USA. [Lewis, Karen T.; Sambruna, Rita M.; Cheung, Chi C.] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA. [Angelakis, Emmanouil] Max Planck Inst Radioastron, DE-53121 Bonn, Germany. [Eracleous, Michael] Penn State Univ, Dept Astron & Astrophys, Davey Lab 525, University Pk, PA 16802 USA. [Eracleous, Michael] Penn State Univ, Ctr Gravitat Wave Phys, Davey Lab 104, University Pk, PA 16802 USA. [Cheung, Chi C.] Natl Acad Sci, Natl Res Council Res Associate, Washington, DC 20001 USA. [Cheung, Chi C.] USN, Res Lab, Washington, DC 20375 USA. [Kadler, Matthias] Univ Erlangen Nurnberg, Dr Remeis Sternwarte Bamberg, D-96049 Bamberg, Germany. [Kadler, Matthias] Univ Erlangen Nurnberg, ECAP, D-96049 Bamberg, Germany. [Kadler, Matthias] CRESST NASA, Greenbelt, MD 20771 USA. [Kadler, Matthias] Univ Space Res Assoc, Columbia, MD 21044 USA. RP Lewis, KT (reprint author), Coll Wooster, Dept Phys, 109 Taylor Hall, Wooster, OH 44691 USA. EM klewis@wooster.edu OI Angelakis, Emmanouil/0000-0001-7327-5441; Kadler, Matthias/0000-0001-5606-6154 FU National Aeronautics and Space Administration [NNX06AF01G, NNH 06CC03B]; Alfred P. Sloan Foundation; National Science Foundation; U.S. Department of Energy; Japanese Monbukagakusho; Max Planck Society; Higher Education Funding Council for England FX We thank V. Braito for advice on the EPIC data reduction. This work was supported by the National Aeronautics and Space Administration through grant number NNX06AF01G. K. T. L. acknowledges support from the NASA Postdoctoral Program Fellowship (NNH 06CC03B). This research has made use of the NASA/IPAC Extragalactic Database (NED) which is operated by the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space Administration. The results of this paper are based on observations with the 100 m telescope of the MPIfR (Max-Planck-Institut fur Radioastronomie) at Effelsberg.; Funding for the SDSS and SDSS-II has been provided by the Alfred P. Sloan Foundation, the Participating Institutions, the National Science Foundation, the U.S. Department of Energy, the National Aeronautics and Space Administration, the Japanese Monbukagakusho, the Max Planck Society, and the Higher Education Funding Council for England. The SDSS Web site is http://www.sdss.org/. NR 53 TC 2 Z9 2 U1 0 U2 3 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-6256 J9 ASTRON J JI Astron. J. PD JUL PY 2011 VL 142 IS 1 AR 9 DI 10.1088/0004-6256/142/1/9 PG 13 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 777AE UT WOS:000291584200009 ER PT J AU ten Brummelaar, TA O'Brien, DP Mason, BD Farrington, CD Fullerton, AW Gies, DR Grundstrom, ED Harkopf, WI Matson, RA McAlister, HA McSwain, MV Roberts, LC Schaefer, GH Simon-Diaz, S Sturmann, J Sturmann, L Turner, NH Williams, SJ AF ten Brummelaar, Theo A. O'Brien, David P. Mason, Brian D. Farrington, Christopher D. Fullerton, Alexander W. Gies, Douglas R. Grundstrom, Erika D. Harkopf, William I. Matson, Rachel A. McAlister, Harold A. McSwain, M. Virginia Roberts, Lewis C., Jr. Schaefer, Gail H. Simon-Diaz, Sergio Sturmann, Judit Sturmann, Laszlo Turner, Nils H. Williams, Stephen J. TI AN INTERFEROMETRIC AND SPECTROSCOPIC ANALYSIS OF THE MULTIPLE STAR SYSTEM HD 193322 SO ASTRONOMICAL JOURNAL LA English DT Article DE binaries: spectroscopic; binaries: visual; stars: early-type; stars: evolution; stars: individual (HD 193322) ID ICCD SPECKLE OBSERVATIONS; O-TYPE STARS; BLANKETED MODEL ATMOSPHERES; BINARY STARS; MASSIVE STARS; BRIGHT STARS; VISUAL ORBIT; CHARA ARRAY; SPECTRA; CALIBRATION AB The star HD 193322 is a remarkable multiple system of massive stars that lies at the heart of the cluster Collinder 419. Here we report on new spectroscopic observations and radial velocities of the narrow-lined component Ab1 which we use to determine its orbital motion around a close companion Ab2 (P = 312 days) and around a distant third star Aa (P = 35 years). We have also obtained long baseline interferometry of the target in the K' band with the CHARA Array which we use in two ways. First, we combine published speckle interferometric measurements with CHARA separated fringe packet measurements to improve the visual orbit for the wide Aa, Ab binary. Second, we use measurements of the fringe packet from Aa to calibrate the visibility of the fringes of the Ab1, Ab2 binary, and we analyze these fringe visibilities to determine the visual orbit of the close system. The two most massive stars, Aa and Ab1, have masses of approximately 21 and 23 M-circle dot, respectively, and their spectral line broadening indicates that they represent extremes of fast and slow projected rotational velocity, respectively. C1 [ten Brummelaar, Theo A.; Farrington, Christopher D.; Schaefer, Gail H.; Sturmann, Judit; Sturmann, Laszlo; Turner, Nils H.] Georgia State Univ, Ctr High Angular Resolut Astron, Mt Wilson, CA 91023 USA. [O'Brien, David P.; Gies, Douglas R.; Matson, Rachel A.; McAlister, Harold A.; Williams, Stephen J.] Georgia State Univ, Dept Phys & Astron, Ctr High Angular Resolut Astron, Atlanta, GA 30302 USA. [Mason, Brian D.; Harkopf, William I.] USN Observ, Washington, DC 20392 USA. [Fullerton, Alexander W.] Space Telescope Sci Inst, Baltimore, MD 21218 USA. [Grundstrom, Erika D.] Vanderbilt Univ, Dept Phys & Astron, Stevenson Ctr 6301, Nashville, TN 37235 USA. [McSwain, M. Virginia] Lehigh Univ, Dept Phys, Bethlehem, PA 18015 USA. [Roberts, Lewis C., Jr.] CALTECH, Jet Prop Lab, Adapt Opt & Astron Instrumentat Grp, Pasadena, CA 91109 USA. [Simon-Diaz, Sergio] Inst Astrofis Canarias, E-38200 San Cristobal la Laguna, Tenerife, Spain. [Simon-Diaz, Sergio] Univ La Laguna, Dept Astrofis, E-38205 Tenerife, Spain. RP ten Brummelaar, TA (reprint author), Georgia State Univ, Ctr High Angular Resolut Astron, Mt Wilson, CA 91023 USA. EM theo@chara-array.org; obrien@chara.gsu.edu; bdm@usno.navy.mil; farrington@chara-array.org; fullerton@stsci.edu; gies@chara.gsu.edu; erika.grundstrom@vanderbilt.edu; wih@usno.navy.mil; rmatson@chara.gsu.edu; hal@chara.gsu.edu; mcswain@lehigh.edu; lewis.c.roberts@jpl.nasa.gov; schaefer@chara-array.org; ssimon@iac.es; nils@chara-array.org; swilliams@chara.gsu.edu OI Grundstrom, Erika/0000-0002-5130-0260 FU National Science Foundation, Georgia State University; W. M. Keck Foundation; David and Lucile Packard Foundation; National Science Foundation [AST-0606861, AST-0606958, AST-0908253, AST-1009080, AST-0440784]; Board of Regents of the University System of Georgia; National Aeronautics and Space Administration through Terrestrial Planet Finder Foundation [NNH06AD70I]; Lehigh University FX The CHARA Array, operated by Georgia State University, was built with funding provided by the National Science Foundation, Georgia State University, the W. M. Keck Foundation, and the David and Lucile Packard Foundation. This material is based upon work supported by the National Science Foundation under grants AST-0606861, AST-0606958, AST-0908253, and AST-1009080. Institutional support has been provided from the GSU College of Arts and Sciences and from the Research Program Enhancement fund of the Board of Regents of the University System of Georgia, administered through the GSU Office of the Vice President for Research. B. D. M. and W. I. H. have been supported by the National Aeronautics and Space Administration under reimbursable no. NNH06AD70I, issued through the Terrestrial Planet Finder Foundation Science program. Thanks are also extended to Ken Johnston and the U. S. Naval Observatory for their continued support of the Double Star Program. M. V. M. thanks Lehigh University for an institutional grant. A portion of the research in this paper was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration. We are grateful to Dr. Gregg Wade and the MiMeS consortium for sharing with us their spectral data on HD 193322 in advance of publication. This work is partially based on spectral data retrieved from the ELODIE archive at Observatoire de Haute-Provence (OHP). Additional spectroscopic data were retrieved from Ritter Observatory's public archive, which was supported by the National Science Foundation Program for Research and Education with Small Telescopes (NSF-PREST) under grant AST-0440784. NR 38 TC 8 Z9 8 U1 0 U2 3 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-6256 J9 ASTRON J JI Astron. J. PD JUL PY 2011 VL 142 IS 1 AR 21 DI 10.1088/0004-6256/142/1/21 PG 14 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 777AE UT WOS:000291584200021 ER PT J AU Storm, DW Patel, AS Koff, SA Justice, SS AF Storm, Douglas W. Patel, Ashay S. Koff, Stephen A. Justice, Sheryl S. TI Novel management of urinary tract infections SO CURRENT OPINION IN UROLOGY LA English DT Review DE interleukin-6; Mutaflor; probiotic; urinary tract infection; vesicoureteral reflux ID ESCHERICHIA-COLI STRAIN; SWEDISH REFLUX TRIAL; VESICOURETERAL REFLUX; ACUTE PYELONEPHRITIS; ANTIBIOTIC-PROPHYLAXIS; NISSLE 1917; CHILDREN; INFANTS; MULTICENTER; PATHOGENS AB Purpose of review To highlight observations that have suggested the need for changing the conventional approach to the evaluation and management of urinary tract infections (UTIs) and vesicoureteral reflux in children and examine new alternative approaches to prevention of UTI and renal scarring based on research into host-pathogen interaction. Recent findings Recent studies have questioned the traditional approach of using prophylactic antibiotics to prevent recurrence of UTI and development of renal scarring in children with vesicoureteral reflux. Ongoing research on host-pathogen interactions reveals a promising capability to analyze virulence factors in bacteria causing UTIs in children, identify highly virulent bacteria capable of causing pyelonephritis and renal injury, and to selectively target the gastrointestinal reservoirs of these bacteria for elimination using probiotics. Summary Promising experimental studies correlating bacterial virulence with pattern of UTI and identification and characterization of a newly available probiotic capable of eradicating uropathogenic bacteria make targeted probiotic prevention of renal injury-inducing UTIs a potential therapeutic reality. C1 [Patel, Ashay S.; Koff, Stephen A.] Nationwide Childrens Hosp, Div Pediat Urol, Columbus, OH 43205 USA. [Storm, Douglas W.] USN, Dept Urol, Med Ctr, San Diego, CA 92152 USA. [Koff, Stephen A.; Justice, Sheryl S.] Ohio State Univ, Sch Med, Columbus, OH 43210 USA. [Justice, Sheryl S.] Nationwide Childrens Hosp, Res Inst, Ctr Microbial Pathogenesis, Columbus, OH 43205 USA. RP Koff, SA (reprint author), Nationwide Childrens Hosp, Div Pediat Urol, 700 Childrens Dr,Timken Hall G280, Columbus, OH 43205 USA. EM Stephen.Koff@nationwidechildrens.org RI Justice, Sheryl/E-3329-2011 OI Justice, Sheryl/0000-0002-7059-3759 FU Research Institute at Nationwide Children's Hospital FX The research funding support is provided by an intramural grant through the Research Institute at Nationwide Children's Hospital. NR 26 TC 5 Z9 5 U1 1 U2 5 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0963-0643 J9 CURR OPIN UROL JI Curr. Opin. Urol. PD JUL PY 2011 VL 21 IS 4 BP 328 EP 333 DI 10.1097/MOU.0b013e328346d4ee PG 6 WC Urology & Nephrology SC Urology & Nephrology GA 775AK UT WOS:000291428400013 PM 21519273 ER PT J AU Avramov-Zamurovic, S Dagalakis, NG Lee, RD Yoo, JM Kim, YS Yang, SH AF Avramov-Zamurovic, Svetlana Dagalakis, Nicholas G. Lee, Rae Duk Yoo, Jae Myung Kim, Yong Sik Yang, Seung Ho TI Embedded Capacitive Displacement Sensor for Nanopositioning Applications SO IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT LA English DT Article; Proceedings Paper CT Conference on Precision Electromagnetic Measurements (CPEM 2010) CY JUN 13-18, 2010 CL Korea Res Inst Standards & Sci, SOUTH KOREA HO Korea Res Inst Standards & Sci DE Capacitance measurement; displacement measurement; fabrication; nano-size positioners; nanotechnology; sensitivity AB The scale of nano-sized objects requires very precise position determination. The state-of-the-art manipulators involve accurate nanometer positioning. This paper presents the design, fabrication process, and testing of a capacitance-based displacement sensor. The nanopositioner application required active sensing area dimensions to be hundreds of micrometers, making it necessary to develop sensor electrodes that are a few micrometers in size. The advantages of the sensor presented are its noninvasive method and very low voltage necessary for signal conditioning. Initial results suggest good linearity and sensitivity of 0.001 pF/mu m, permitting a reliable displacement resolution on the order of 100 nm. C1 [Avramov-Zamurovic, Svetlana] USN Acad, Annapolis, MD 21402 USA. [Dagalakis, Nicholas G.; Lee, Rae Duk; Yoo, Jae Myung; Kim, Yong Sik; Yang, Seung Ho] NIST, Gaithersburg, MD 20899 USA. RP Avramov-Zamurovic, S (reprint author), USN Acad, Annapolis, MD 21402 USA. EM avramov@usna.edu NR 14 TC 4 Z9 4 U1 3 U2 11 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0018-9456 J9 IEEE T INSTRUM MEAS JI IEEE Trans. Instrum. Meas. PD JUL PY 2011 VL 60 IS 7 BP 2730 EP 2737 DI 10.1109/TIM.2011.2126150 PG 8 WC Engineering, Electrical & Electronic; Instruments & Instrumentation SC Engineering; Instruments & Instrumentation GA 775BQ UT WOS:000291432000094 ER PT J AU Mott, PH Smallhorn, JM Campbell, KW Schrader, HL Cartwright, CL Finck, DG AF Mott, Peter H. Smallhorn, Jodi M. Campbell, Ken W. Schrader, Howard L. Cartwright, Craig L. Finck, Darren G. TI Comparison of buckling of an arched, rubber-core sandwich composite panel to finite element modeling SO COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING LA English DT Article DE Layered structures; Buckling; Finite element analysis (FEA); Mechanical testing ID DEFORMATION; BEHAVIOR; PLATES AB Finite element modeling was developed for buckling of an unbalanced fiberglass-rubber sandwich composite panels under hydrostatic pressure. The analysis was verified with tests on two sets of full-scale panels with different rubber cores. The model was composed of solid elements for the core, and shell elements with a neutral axis offset for the skins. An accurate description of the nonlinear rubber at strains <5% was crucial. The buckling pressures predicted by the model were 148 +/- 7 and 323 +/- 24 kPa for the two sets of panels, which agreed well with the measured values of 147 +/- 2 and 317 +/- 7 kPa, respectively. At low pressure, there was agreement of deflections and strains from the model to the measurement, but at high pressure the agreement was unsatisfactory. A secondary elastic instability was observed, occurring more suddenly in the model. The differences were ascribed to the lack of inclusion of defects in the model. Published by Elsevier Ltd. C1 [Mott, Peter H.] USN, Div Chem, Res Lab, Washington, DC 20375 USA. [Smallhorn, Jodi M.; Campbell, Ken W.; Schrader, Howard L.] Sci Applicat Int Corp, La Plata, MD 20646 USA. [Cartwright, Craig L.; Finck, Darren G.] Goodrich Corp, Jacksonville, FL 32226 USA. RP Mott, PH (reprint author), USN, Div Chem, Res Lab, Washington, DC 20375 USA. EM peter.mott@nrl.navy.mil; darren.finck@goodrich.com FU Naval Sea System Command FX We are indebted to M. Weiner for the initial analysis of the prototype failure. We also gratefully acknowledge discussions on the Payne effect with C.M. Roland and R. Bogoslovov. This work was supported by the Naval Sea System Command. NR 26 TC 2 Z9 2 U1 1 U2 5 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 1359-835X EI 1878-5840 J9 COMPOS PART A-APPL S JI Compos. Pt. A-Appl. Sci. Manuf. PD JUL PY 2011 VL 42 IS 7 BP 843 EP 848 DI 10.1016/j.compositesa.2011.03.013 PG 6 WC Engineering, Manufacturing; Materials Science, Composites SC Engineering; Materials Science GA 773HH UT WOS:000291297100016 ER PT J AU Hu, QC Osswald, S Daniel, R Zhu, Y Wesel, S Ortiz, L Sadoway, DR AF Hu, Qichao Osswald, Sebastian Daniel, Reece Zhu, Yan Wesel, Steven Ortiz, Luis Sadoway, Donald R. TI Graft copolymer-based lithium-ion battery for high-temperature operation SO JOURNAL OF POWER SOURCES LA English DT Article DE Graft copolymer; Polymer electrolyte; PEO; Lithium-ion battery; LiFePO(4); High temperature ID PROPYLENE CARBONATE SOLUTIONS; NANOCOMPOSITE POLYMER ELECTROLYTES; THERMAL-STABILITY; ROOM-TEMPERATURE; IMPEDANCE SPECTROSCOPY; SOLID-ELECTROLYTE; THIN-FILM; ELECTROCHEMICAL IMPEDANCE; RECHARGEABLE BATTERIES; LIXCOO2 CATHODE AB The use of conventional lithium-ion batteries in high temperature applications (>50 degrees C) is currently inhibited by the high reactivity and volatility of liquid electrolytes. Solvent-free, solid-state polymer electrolytes allow for safe and stable operation of lithium-ion batteries, even at elevated temperatures. Recent advances in polymer synthesis have led to the development of novel materials that exhibit solid-like mechanical behavior while providing the ionic conductivities approaching that of liquid electrolytes. Here we report the successful charge and discharge cycling of a graft copolymer electrolyte (GCE)-based lithium-ion battery at temperatures up to 120 degrees C. The GCE consists of poly(oxyethylene) methacrylate-g-poly(dimethyl siloxane) (POEM-g-PDMS) doped with lithium triflate. Using electrochemical impedance spectroscopy (EIS), we analyze the temperature stability and cycling behavior of GCE-based lithium-ion batteries comprised of a LiFePO(4) cathode, a metallic lithium anode, and an electrolyte consisting of a 20-mu m-thick layer of lithium triflate-doped POEM-g-PDMS. Our results demonstrate the great potential of GCE-based Li-ion batteries for high-temperature applications. (C) 2011 Elsevier B.V. All rights reserved. C1 [Hu, Qichao; Osswald, Sebastian; Daniel, Reece; Zhu, Yan; Wesel, Steven; Ortiz, Luis; Sadoway, Donald R.] MIT, Dept Mat Sci & Engn, Cambridge, MA 02139 USA. [Hu, Qichao] Harvard Univ, Sch Engn & Appl Sci, Dept Appl Phys, Cambridge, MA 02138 USA. [Osswald, Sebastian] USN, Postgrad Sch, Dept Phys, Grad Sch Engn & Appl Sci, Monterey, CA 93943 USA. RP Sadoway, DR (reprint author), MIT, Dept Mat Sci & Engn, Cambridge, MA 02139 USA. EM dsadoway@mit.edu FU Chevron; Harvard Graduate Consortium on Energy and Environment FX This work was supported in part by Chevron. Qichao Hu would also like to thank the Harvard Graduate Consortium on Energy and Environment for its fellowship. NR 63 TC 26 Z9 27 U1 11 U2 96 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0378-7753 J9 J POWER SOURCES JI J. Power Sources PD JUL 1 PY 2011 VL 196 IS 13 SI SI BP 5604 EP 5610 DI 10.1016/j.jpowsour.2011.03.001 PG 7 WC Chemistry, Physical; Electrochemistry; Energy & Fuels; Materials Science, Multidisciplinary SC Chemistry; Electrochemistry; Energy & Fuels; Materials Science GA 771GA UT WOS:000291144000031 ER PT J AU Sparks, S DeCambre, M Christman, M Kaplan, G Holmes, N AF Sparks, Scott DeCambre, Marvalyn Christman, Matthew Kaplan, George Holmes, Nicholas TI Salvage Ureteral Reimplantation After Failure of Dextranomer/Hyaluronic Acid Injection SO JOURNAL OF UROLOGY LA English DT Article DE deflux; dextranomer-hyaluronic acid copolymer; replantation; ureter; ureterostomy ID PRIMARY VESICOURETERAL REFLUX; ENDOSCOPIC CORRECTION; COPOLYMER; MANAGEMENT; CHILDREN AB Purpose: Ureteroneocystostomy after dextranomer/hyaluronic acid injection is reportedly associated with significantly more morbidity, and increased operative time, length of stay and postoperative obstruction. To evaluate our experience, we reviewed results of patients who underwent salvage ureteral reimplantation following failed dextranomer/hyaluronic acid injection. Materials and Methods: We retrospectively reviewed charts of patients at a single institution who underwent intravesical ureteral reimplantation as salvage treatment following failed dextranomer/hyaluronic acid injection. Data points such as operative time, blood loss and length of stay were compared to those of controls undergoing de novo reimplantation by the same surgeons. Statistical analysis was performed using Student's t test and chi-square test. Results: We identified 18 patients who underwent salvage reimplant. We compared data to an equal number of controls. Mean age (4.28 years in patients vs 3.34 years in controls, p = 0.62) and mean reflux grade at reimplant (3.15 vs 3.40, p = 0.97) were comparable between the groups. Operative time (128 vs 141.9 minutes, p = 0.14), blood loss (12.9 vs 11.9 ml, p = 0.71) and length of hospital stay (1.68 vs 1.3 days, p = 0.25) were not significantly different. No statistically significant differences were found regarding any of the compared variables. Conclusions: Ureteral reimplantation after dextranomer/hyaluronic acid injection is no more difficult than primary ureteral reimplantation regarding operative time, blood loss and length of hospital stay. These results support dextranomer/hyaluronic acid as initial operative treatment of vesicoureteral reflux when deemed appropriate and may further shift the paradigm of treatment away from prolonged medical management. C1 [Sparks, Scott] Univ Calif San Diego, San Diego, CA 92103 USA. [Christman, Matthew] USN, Med Ctr, San Diego, CA 92152 USA. RP Sparks, S (reprint author), Univ Calif San Diego, San Diego, CA 92103 USA. NR 16 TC 1 Z9 1 U1 0 U2 0 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 0022-5347 J9 J UROLOGY JI J. Urol. PD JUL PY 2011 VL 186 IS 1 BP 257 EP 260 DI 10.1016/j.juro.2011.03.048 PG 4 WC Urology & Nephrology SC Urology & Nephrology GA 775PH UT WOS:000291472900094 PM 21575977 ER PT J AU Prabhakaran, K Chapman, GD Gunasekar, PG AF Prabhakaran, Krishnan Chapman, Gail D. Gunasekar, Palur G. TI alpha-Synuclein overexpression enhances manganese-induced neurotoxicity through the NF-kappa B-mediated pathway SO TOXICOLOGY MECHANISMS AND METHODS LA English DT Article DE Manganese; alpha-Synuclein; Oxidative stress; NF-kappa B; p38 MAPK; Nitric oxide; Apoptosis ID SH-SY5Y NEUROBLASTOMA-CELLS; PARKINSONS-DISEASE; INDUCED APOPTOSIS; OXIDATIVE STRESS; SIGNALING PATHWAYS; DROSOPHILA MODEL; NEURONAL CELLS; RAT ASTROCYTES; GROWTH-FACTOR; LEWY BODIES AB Exposure to manganese (Mn) occurs in both civilian and military operations. Mn exposure results in a movement disorder termed manganism, which resembles Parkinson's disease (PD). However, the pathogenic mechanisms underlying this disorder are not fully understood. alpha-Synuclein, a presynaptic protein is implicated in some neurodegenerative disorders, including PD and Mn-induced apoptosis, and its overexpression contributes to the loss of dopaminergic neurons. Although the role of a-synuclein in this process is widely documented, its exact function is not clear. The objective of this study was to evaluate the mechanism(s) of dopaminergic degeneration associated with a-synuclein expression in response to Mn exposure and to assess the role of nuclear factor-kappa B (NF-kappa B) activation as an intermediary of Mn-induced neurotoxicity. Rat mesencephalic cells (MES 23.5) overexpressing human a-synuclein show enhanced susceptibility to Mn exposure as evidenced by increased apoptosis and NF-kappa B nuclear translocation. Pretreatment with antioxidants and the p38 mitogen-activated protein kinase (MAPK) inhibitor SB239063 significantly diminished NF-kappa B activation, supporting a role for oxidative stress and p38 MAPK in Mn-induced NF-kappa B activation. In addition, increased nitric oxide generation was evident during NF-kappa B activation, which was blocked by NF-kappa B (SN50) and MAPK inhibitors. Mn-induced cell death was attenuated by SN-50 and specific nitric oxide synthase (NOS) inhibitor (1400W); corroborating NOS activation is mediated through NF-kappa B in the mechanism of cell death. These data indicate that the transcription factor NF-kappa B, p38 MAPK, and apoptotic signaling cascades are activated by Mn in human alpha-synuclein-overexpressing cells. Thus, alpha-synuclein may facilitate Mn-induced neurotoxicity, and along with NF-kappa B, it may play a role in dopaminergic cell death. C1 [Prabhakaran, Krishnan; Chapman, Gail D.; Gunasekar, Palur G.] USN, Med Res Unit Dayton NAMRU D, Dayton, OH 45433 USA. RP Gunasekar, PG (reprint author), USN, Med Res Unit Dayton NAMRU D, Dayton, OH 45433 USA. EM Palur.gunasekar@wpafb.af.mil FU [70262] FX The views expressed in this article are those of the author and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, nor the US Government. This work was supported, funded in part, by work unit number 70262. P. G. G. is a military service member (or employee of the US Government). This work was prepared as part of his official duties. Title 17 U. S. C. 105 provided that 'Copyright protection under this title is not available for any work of the United States Government,' Title 17 U. S. C. 101 define a US Government work as a work prepared by a military service member or employee of the US Government as part of that person's official duties. This research was supported in part by an appointment to the Postgraduate Research Participation Program at the Naval Medical Research Unit Dayton administered by Oak Ridge Institute for Science and Education through an interagency agreement between the US Department of Energy and NAMRU-D. NR 57 TC 14 Z9 15 U1 0 U2 2 PU TAYLOR & FRANCIS LTD PI ABINGDON PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND SN 1537-6516 EI 1537-6524 J9 TOXICOL MECH METHOD JI Toxicol. Mech. Methods PD JUL PY 2011 VL 21 IS 6 BP 435 EP 443 DI 10.3109/15376516.2011.560210 PG 9 WC Toxicology SC Toxicology GA 774ND UT WOS:000291392400001 PM 21417633 ER PT J AU Jacobus, H Lin, BC Jimmy, DH Ansumana, R Malanoski, AP Stenger, D AF Jacobus, Headley Lin, Baochuan Jimmy, David Henry Ansumana, Rashid Malanoski, Anthony P. Stenger, David TI Evaluating the impact of adding energy storage on the performance of a hybrid power system SO ENERGY CONVERSION AND MANAGEMENT LA English DT Article DE Hybrid power; Diesel-only generator; Load profile; Battery bank; Generation cost; Operation and maintenance ID PV-DIESEL SYSTEMS; DISPATCH STRATEGY; SOLAR; DESIGN; OPTIMIZATION; REGIONS AB Hybrid power systems have the capability to incorporate significant renewable energy penetration for a small autonomous system while still maintaining reliable grid stability. While there are many papers covering the optimization of component size and dispatch strategy, far fewer papers contain experimental performance data from hybrid systems. Mercy Hospital in Bo, Sierra Leone is converting their power system into a photovoltaic (PV)-diesel hybrid system, thus providing an opportunity to examine the change in system performance before, during, and after the conversion. Due to the seasonal availability of electric power in Sierra Leone, two datasets representing two distinct load profiles are analyzed: Wet Season and Dry Season. The difference in generation efficiency, cost per kW h, generator runtime, and fuel consumption are calculated between a diesel-only generation baseline and the recorded hybrid system performance. The results indicated that the hybrid system significantly reduces operation costs; approximately 37% less during Dry Season and 64% reduction in the Wet Season than a diesel-only generator serving the same load. Published by Elsevier Ltd. C1 [Jacobus, Headley; Lin, Baochuan; Malanoski, Anthony P.; Stenger, David] USN, Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. [Jacobus, Headley] Nova Res Inc, Alexandria, VA 22308 USA. [Jimmy, David Henry; Ansumana, Rashid] Mercy Hosp Res Lab, Kulando Town, Bo, Sierra Leone. RP Stenger, D (reprint author), USN, Res Lab, Ctr Bio Mol Sci & Engn, Code 6900,4555 Overlook Ave SW, Washington, DC 20375 USA. EM jacobush@gmail.com; baochuan.lin@nrl.navy.mil; dave_jimmy07@yahoo.co.uk; rashidansumana@gmail.com; Anthony.malanoski@nri.navy.mil; david.stenger@nrl.navy.mil RI Malanoski, Anthony/C-7814-2011; Lin, Baochuan/A-8390-2009 OI Malanoski, Anthony/0000-0001-6192-888X; Lin, Baochuan/0000-0002-9484-0785 FU Office of Naval Research; Office of under Secretary of Defense for Acquisition, Technology, and Logistics; Nova Research, Inc. FX The funding for this project is provided by the Office of Naval Research and the Office of under Secretary of Defense for Acquisition, Technology, and Logistics. The support given by Nova Research, Inc., Mr. Russ Jefferies in particular, was greatly appreciated. The opinions and assertions contained herein are those of the authors and none are to be construed as those of the US Department of Defense, US Department of the Navy or any other military service or government agency at large. NR 22 TC 18 Z9 18 U1 0 U2 10 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0196-8904 J9 ENERG CONVERS MANAGE JI Energy Conv. Manag. PD JUL PY 2011 VL 52 IS 7 BP 2604 EP 2610 DI 10.1016/j.enconman.2011.01.015 PG 7 WC Thermodynamics; Energy & Fuels; Mechanics SC Thermodynamics; Energy & Fuels; Mechanics GA 762VD UT WOS:000290508700016 ER PT J AU Gordis, JH Papagiannakis, K AF Gordis, Joshua H. Papagiannakis, Konstantinos TI Optimal selection of artificial boundary conditions for model update and damage detection SO MECHANICAL SYSTEMS AND SIGNAL PROCESSING LA English DT Article DE Identification; Artificial boundary conditions; QR decomposition ID ANTIRESONANCES; FREQUENCIES AB Sensitivity-based model error localization and damage detection is hindered by the relative differences in modal sensitivity magnitude among updating parameters. The method of artificial boundary conditions is shown to directly address this limitation, resulting in the increase of the number of updating parameters at which errors can be accurately localized. Using a single set of FRF data collected from a modal test, the artificial boundary conditions (ABC) method identifies experimentally the natural frequencies of a structure under test for a variety of different boundary conditions, without having to physically apply the boundary conditions, hence the term "artificial". The parameter-specific optimal ABC sets applied to the finite element model will produce increased sensitivities in the updating parameter, yielding accurate error localization and damage detection solutions. A method is developed for identifying the parameter-specific optimal ABC sets for updating or damage detection, and is based on the QR decomposition with column pivoting. Updating solution residuals, such as magnitude error and false error location, are shown to be minimized when the updating parameter set is limited to those corresponding to the QR pivot columns. The existence of an optimal ABC set for a given updating parameter is shown to be dependent on the number of modes used, and hence the method developed provides a systematic determination of the minimum number of modes required for localization in a given updating parameter. These various concepts are demonstrated on a simple model with simulated test data. Published by Elsevier Ltd. C1 [Gordis, Joshua H.] USN, Postgrad Sch, Dept Mech & Aerosp Engn Code ME Go, Monterey, CA 93943 USA. [Papagiannakis, Konstantinos] Hellen Navy, Athens, Greece. RP Gordis, JH (reprint author), USN, Postgrad Sch, Dept Mech & Aerosp Engn Code ME Go, 700 Dyer Rd,Bldg 245,Room 313, Monterey, CA 93943 USA. EM jgordis@nps.edu NR 29 TC 2 Z9 2 U1 1 U2 9 PU ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD PI LONDON PA 24-28 OVAL RD, LONDON NW1 7DX, ENGLAND SN 0888-3270 J9 MECH SYST SIGNAL PR JI Mech. Syst. Signal Proc. PD JUL PY 2011 VL 25 IS 5 BP 1451 EP 1468 DI 10.1016/j.ymssp.2010.12.009 PG 18 WC Engineering, Mechanical SC Engineering GA 763IT UT WOS:000290550700002 ER PT J AU Yoon, H Bateman, BE Agrawal, BN AF Yoon, Hyungjoo Bateman, Brett E. Agrawal, Brij N. TI Laser Beam Jitter Control Using Recursive-Least-Squares Adaptive Filters SO JOURNAL OF DYNAMIC SYSTEMS MEASUREMENT AND CONTROL-TRANSACTIONS OF THE ASME LA English DT Article ID FEEDBACK-CONTROL; REJECTION AB The primary focus of this research is to develop and implement control schemes for combined broadband and narrowband disturbances to optical beams. The laser beam jitter control testbed developed at the Naval Postgraduate School is used for development of advanced jitter control techniques. First, we propose a least quadratic Gaussian feedback controller with integrator for cases when only the error signal ( the difference between the desired and the actual beam positions) is available. An anti-notch filter is also utilized to attenuate a vibrational disturbance with a known frequency. Next, we develop feedforward adaptive filter methods for cases when a reference signal, which is highly correlated with the jitter disturbance, is available. A filtered-X recursive least-squares algorithm with an integrated bias estimator is proposed to deal with a constant bias disturbance. Finally, experimental results are provided to validate and compare the performance of the developed control techniques. The designed adaptive filter has a simple structure but shows good jitter rejection performance, thanks to the use of a reference signal. [DOI:10.1115/1.4003372] C1 [Yoon, Hyungjoo] Korea Aerosp Res Inst, Satellite Control Syst Dept, Taejon 305333, South Korea. [Bateman, Brett E.] USN, Dept Phys, Postgrad Sch, Monterey, CA 93943 USA. [Agrawal, Brij N.] USN, Dept Mech & Astronaut Engn, Postgrad Sch, Monterey, CA 93943 USA. [Agrawal, Brij N.] USN, Space Res & Design Ctr, Postgrad Sch, Monterey, CA 93943 USA. RP Yoon, H (reprint author), Korea Aerosp Res Inst, Satellite Control Syst Dept, Taejon 305333, South Korea. EM drake.yoon@gmail.com; batemans2001@att.net; agrawal@nps.edu NR 16 TC 1 Z9 1 U1 0 U2 3 PU ASME PI NEW YORK PA TWO PARK AVE, NEW YORK, NY 10016-5990 USA SN 0022-0434 EI 1528-9028 J9 J DYN SYST-T ASME JI J. Dyn. Syst. Meas. Control-Trans. ASME PD JUL PY 2011 VL 133 IS 4 AR 041001 DI 10.1115/1.4003372 PG 8 WC Automation & Control Systems; Instruments & Instrumentation SC Automation & Control Systems; Instruments & Instrumentation GA 748GU UT WOS:000289379000001 ER PT J AU Varney, RH Hysell, DL Huba, JD AF Varney, R. H. Hysell, D. L. Huba, J. D. TI Sensitivity studies of equatorial topside electron and ion temperatures SO JOURNAL OF GEOPHYSICAL RESEARCH-SPACE PHYSICS LA English DT Article ID INCOHERENT-SCATTER SPECTRUM; F-REGION; PHOTOELECTRON TRANSPORT; ISOTROPIC SCATTERING; LATITUDE IONOSPHERE; COULOMB COLLISIONS; EARTHS IONOSPHERE; ANALYTIC APPROACH; MODEL; JICAMARCA AB Even in the recent extremely low solar minimum the electron and ion temperatures in the low-latitude topside ionosphere display a great deal of day-to-day variability. This paper explores this variability using both the SAMI2 model and a newly developed steady state model of the plasma temperatures. Variations in the electric fields and neutral winds both produce drastic changes in the temperature profiles predicted above the magnetic equator. This implies that information about these parameters is contained in the temperature profiles measured at Jicamarca. Both winds and electric fields alter the arrangement of plasma throughout the entire low-latitude ionosphere, including the locations and densities of the equatorial arcs. These changes have a much larger effect on the topside temperatures above the equator than changing the local advection or expansion alone because the topside equatorial temperatures are strongly coupled to the off-equatorial F regions by field-aligned thermal diffusion and photoelectron transport. The temperatures are more sensitive to changes in the nonlocal photoelectron heating than any other individual effect. The nonlocal photoelectron heating model used is still fairly primitive, however. The extreme sensitivity of the temperatures to the photoelectron transport model used means that more sophisticated photoelectron heating models will need to be used before meaningful comparisons between the model and observations can be made. C1 [Varney, R. H.] Cornell Univ, Sch Elect & Comp Engn, Ithaca, NY 14853 USA. [Hysell, D. L.] Cornell Univ, Dept Earth & Atmospher Sci, Ithaca, NY 14853 USA. [Huba, J. D.] USN, Res Lab, Div Plasma Phys, Washington, DC 20375 USA. RP Varney, RH (reprint author), Cornell Univ, Sch Elect & Comp Engn, 303 Rhodes Hall, Ithaca, NY 14853 USA. EM rhv5@cornell.edu RI Varney, Roger/A-6048-2011; OI Varney, Roger/0000-0002-5976-2638 FU ONR; NSF through Cornell University [AGS-0905448] FX This research has been funded, in part, by ONR (JDH). The Jicamarca Radio Observatory is a facility of the Instituto Geofisico del Peru operated with support from NSF cooperative agreement AGS-0905448 through Cornell University. NR 52 TC 6 Z9 6 U1 0 U2 2 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 2169-9380 EI 2169-9402 J9 J GEOPHYS RES-SPACE JI J. Geophys. Res-Space Phys. PD JUN 30 PY 2011 VL 116 AR A06321 DI 10.1029/2011JA016549 PG 13 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 787RS UT WOS:000292395000005 ER PT J AU Schiller, RV Kourafalou, VH Hogan, P Walker, ND AF Schiller, R. V. Kourafalou, V. H. Hogan, P. Walker, N. D. TI The dynamics of the Mississippi River plume: Impact of topography, wind and offshore forcing on the fate of plume waters SO JOURNAL OF GEOPHYSICAL RESEARCH-OCEANS LA English DT Article ID GULF-OF-MEXICO; LOUISIANA CONTINENTAL-SHELF; COORDINATE OCEAN MODEL; LOW-FREQUENCY CIRCULATION; LOW-SALINITY WATERS; WEST FLORIDA SHELF; LOOP CURRENT; EASTERN GULF; VERTICAL COORDINATE; DATA ASSIMILATION AB High-resolution numerical simulations of the northern Gulf of Mexico region using the Hybrid Coordinate Ocean Model (HYCOM) were employed to investigate the dynamical processes controlling the fate of the Mississippi River plume, in particular the conditions that favor cross-marginal transport. The study focuses on the effects of topography, wind-driven and eddy-driven circulation on the offshore removal of plume waters. A realistically forced simulation (nested in a data-assimilative regional Gulf of Mexico HYCOM model) reveals that the offshore removal is a frequent plume pathway. Eastward wind-driven currents promote large freshwater transport toward the shelf break and the DeSoto Canyon, where eddies with diameters ranging from 50 to 130 km interact with the buoyant plume and effectively entrain the riverine waters. Our estimates show that the offshore removal by eddies can be as large as the wind-driven shelf transport. The proximity of eddies to the shelf break is a sufficient condition for offshore removal, and shelf-to-offshore interaction is facilitated by the steep bottom topography near the delta. Strong eddy-plume interactions were observed when the Loop Current System impinged against the shelf break, causing the formation of coherent, narrow low-salinity bands that extended toward the gulf interior. The offshore pathways depend on the position of the eddies near the shelf edge, their life span and the formation of eddy pairs that generate coherent cross-shelf flows. This study elucidates the dynamics that initiate a unique cross-marginal removal mechanism of riverine low-salinity, nutrient-rich waters, allowing their export along connectivity pathways, induced by a large-scale current system. C1 [Schiller, R. V.; Kourafalou, V. H.] Univ Miami, Rosenstiel Sch Marine & Atmospher Sci, Miami, FL 33149 USA. [Hogan, P.] USN, Res Lab, Stennis Space Ctr, MS 39529 USA. [Walker, N. D.] Louisiana State Univ, Dept Oceanog & Coastal Sci, Baton Rouge, LA 70803 USA. RP Schiller, RV (reprint author), Univ Miami, Rosenstiel Sch Marine & Atmospher Sci, 4600 Rickenbacker Cswy, Miami, FL 33149 USA. EM rschiller@rsmas.miami.edu RI Walker, Nan/D-8819-2013 FU National Science Foundation [NSF OCE-0929651]; National Oceanic and Atmospheric Administration [NOAA NA17RJ1226]; Office of Naval Research [N000140510892] FX The study was funded by the National Science Foundation (NSF OCE-0929651) and the National Oceanic and Atmospheric Administration (NOAA NA17RJ1226). Additional funding for V. H. Kourafalou and P. Hogan was available from the Office of Naval Research through the National Ocean Partnership Program (ONR/NOPP N000140510892). The authors are very thankful to Richard Patchen (NOAA National Ocean Service) for providing the realistic river discharge data set employed in this study, to Robert Leben (University of Colorado) for providing the Loop Current tracking program that was used in the analysis of model results and to Chet Pilley (Earth Scan Laboratory, Louisiana State University) for his assistance with satellite image processing. NR 66 TC 52 Z9 53 U1 4 U2 31 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 0148-0227 J9 J GEOPHYS RES-OCEANS JI J. Geophys. Res.-Oceans PD JUN 30 PY 2011 VL 116 AR C06029 DI 10.1029/2010JC006883 PG 22 WC Oceanography SC Oceanography GA 787NW UT WOS:000292384700003 ER PT J AU Stotland, A Pecora, LM Cohen, D AF Stotland, Alexander Pecora, Louis M. Cohen, Doron TI "Weak quantum chaos" and its resistor network modeling SO PHYSICAL REVIEW E LA English DT Article ID ERGODIC ADIABATIC INVARIANTS; RANDOM-MATRIX ENSEMBLE; ONE-BODY DISSIPATION; STATISTICAL PROPERTIES; SPECTRAL STATISTICS; NONPERTURBATIVE RESPONSE; SEMILINEAR RESPONSE; MESOSCOPIC SYSTEMS; ENERGY-ABSORPTION; LOCALIZATION AB Weakly chaotic or weakly interacting systems have a wide regime where the common random matrix theory modeling does not apply. As an example we consider cold atoms in a nearly integrable optical billiard with a displaceable wall (piston). The motion is completely chaotic but with a small Lyapunov exponent. The Hamiltonian matrix does not look like one taken from a Gaussian ensemble, but rather it is very sparse and textured. This can be characterized by parameters s and g which reflect the percentage of large elements and their connectivity, respectively. For g we use a resistor network calculation that has a direct relation to the semilinear response characteristics of the system, hence leading to a prediction regarding the energy absorption rate of cold atoms in optical billiards with vibrating walls. C1 [Stotland, Alexander] Ben Gurion Univ Negev, Dept Phys, IL-84105 Beer Sheva, Israel. [Pecora, Louis M.; Cohen, Doron] USN, Res Lab, Washington, DC 20375 USA. RP Stotland, A (reprint author), Ben Gurion Univ Negev, Dept Phys, IL-84105 Beer Sheva, Israel. RI Cohen, Doron/D-4564-2009 OI Cohen, Doron/0000-0002-3835-3544 FU U.S.-Israel Binational Science Foundation (BSF) FX We thank Nir Davidson (Weizmann) for a crucial discussion regarding the experimental details. This research has been supported by the U.S.-Israel Binational Science Foundation (BSF). NR 60 TC 4 Z9 4 U1 0 U2 2 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1539-3755 EI 1550-2376 J9 PHYS REV E JI Phys. Rev. E PD JUN 30 PY 2011 VL 83 IS 6 AR 066216 DI 10.1103/PhysRevE.83.066216 PN 2 PG 17 WC Physics, Fluids & Plasmas; Physics, Mathematical SC Physics GA 785WP UT WOS:000292263700003 PM 21797470 ER PT J AU Handler, RA Smith, GB AF Handler, Robert A. Smith, Geoffrey B. TI Statistics of the temperature and its derivatives at the surface of a wind-driven air-water interface SO JOURNAL OF GEOPHYSICAL RESEARCH-OCEANS LA English DT Article ID INFRARED IMAGE SEQUENCES; SEA GAS TRANSFER; THERMAL STRUCTURE; MOLECULAR SUBLAYER; COOL SKIN; OCEAN; FLOW; SUBJECT; RENEWAL; MODEL AB The statistics of the temperature and its spatial derivatives at a wind-driven air-water interface were obtained from a comprehensive data set of high resolution infrared imagery for wind speeds ranging from 2 ms(-1) to 10 ms(-1). We focus our effort on considerations of the anisotropy, symmetry, and intermittency of the surface turbulence. The analysis reveals that the root-mean-square surface temperature, when made nondimensional by using the surface heat flux and friction velocity, is nearly independent of Richardson number (Ri, defined in section 2). In addition, the derivatives of the thermal field appear also to converge to a limiting value at low Ri. The skewness of the temperature field, though slightly positive for the lowest wind speed (2 ms(-1)), is otherwise negative. On the other hand, the skewness of the derivative of the temperature field in the along-wind direction is strictly positive, while the skewness in the cross-wind direction is essentially zero, owing to the spanwise symmetry of the flow. This has the consequence that wind direction can be estimated by computing the skewness of the directional derivative of the temperature field. The flatness of the temperature field is observed to be near the Gaussian value of 3 throughout the wind speed range, while the along-wind and cross-wind derivatives show non-Gaussian behavior, indicating the presence of intermittency in the thermal fields at small scales. All probability density functions of the temperature derivatives are seen to have Gaussian cores, with distinct exponential tails. C1 [Handler, Robert A.; Smith, Geoffrey B.] USN, Res Lab, Washington, DC 20375 USA. RP Handler, RA (reprint author), USN, Res Lab, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM geoffrey.smith@nrl.navy.mil FU Office of Naval Research through the Naval Research Laboratory; DOD; Office of Naval Research [N00014-03-1-0384] FX The authors acknowledge the support of the Office of Naval Research through the Naval Research Laboratory, and also the support of the DOD High Performance Computing Program. We also acknowledge the assistance of Peter Minnett and other staff members at the Rosenstiel School (RSMAS) of the University of Miami. Funding to conduct the experiments was provided to RSMAS by the Office of Naval Research under award N00014-03-1-0384. NR 46 TC 6 Z9 6 U1 2 U2 10 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 0148-0227 J9 J GEOPHYS RES-OCEANS JI J. Geophys. Res.-Oceans PD JUN 28 PY 2011 VL 116 AR C06021 DI 10.1029/2010JC006496 PG 14 WC Oceanography SC Oceanography GA 787NU UT WOS:000292384500002 ER PT J AU Zhao, HB Fan, Y Lupke, G Hanbicki, AT Li, CH Jonker, BT AF Zhao, H. B. Fan, Y. Luepke, G. Hanbicki, A. T. Li, C. H. Jonker, B. T. TI Detection of coherent acoustic phonons by time-resolved second-harmonic generation SO PHYSICAL REVIEW B LA English DT Article ID LIGHT-PULSES; SPECTROSCOPY AB We report on observation of coherent longitudinal acoustic phonons in Fe/AlGaAs (001) heterostructure by time-resolved second-harmonic generation (TRSHG). The phonon induces not only a fast and highly damped oscillatory signal but also a long-lived one that exhibits an oscillating period identical to that obtained from the reflectivity measurement. The long-lived oscillatory second-harmonic generation is generated by an electric field modulated at 42.5 GHz because of the interference of the incident beam and the reflected light by the propagating phonon. TRSHG lets us probe the internal field modulated by phonons and differentiate their impacts at the interface and in the bulk. C1 [Zhao, H. B.; Fan, Y.; Luepke, G.] Coll William & Mary, Dept Appl Sci, Williamsburg, VA 23185 USA. [Zhao, H. B.] Fudan Univ, Dept Opt Sci & Engn, Key Lab Micro & Nano Photon Struct, Minist Educ, Shanghai 200433, Peoples R China. [Hanbicki, A. T.; Li, C. H.; Jonker, B. T.] USN, Res Lab, Washington, DC 20375 USA. RP Zhao, HB (reprint author), Coll William & Mary, Dept Appl Sci, Williamsburg, VA 23185 USA. EM hbzhao@fudan.edu.cn RI Fan, Yichun/F-4234-2012 FU Office of Naval Research; National Natural Science Foundation of China [60908005, 11074044]; Shanghai Pujiang Program; Okawa Foundation FX This work was sponsored in part by the Office of Naval Research, National Natural Science Foundation of China (Grants No. 60908005 and No. 11074044), Shanghai Pujiang Program, and Okawa Foundation. NR 20 TC 7 Z9 7 U1 2 U2 17 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1098-0121 J9 PHYS REV B JI Phys. Rev. B PD JUN 28 PY 2011 VL 83 IS 21 AR 212302 DI 10.1103/PhysRevB.83.212302 PG 4 WC Physics, Condensed Matter SC Physics GA 784UA UT WOS:000292182500001 ER PT J AU Petrova, TB Whitney, KG Davis, J AF Petrova, Tz B. Whitney, K. G. Davis, J. TI X-ray amplification dynamics at similar to 2.8 angstrom in intense laser irradiated xenon clusters: multiple hole dynamics SO JOURNAL OF PHYSICS B-ATOMIC MOLECULAR AND OPTICAL PHYSICS LA English DT Article ID RECOMBINATION RATE COEFFICIENTS; ISOSEQUENCES; IONIZATION; IONS; FE; CA; MG; NI; AR; SI AB In a series of experiments (Borisov et al 2008 J. Phys. B: At. Mol. Opt. Phys. 41 105602, and references 1 through 7 cited in this paper), the amplification of 2.71-2.88 angstrom x-rays was observed, gain coefficients between 27 and 104 cm(-1) were measured, and a number of conjectures were made concerning the ionization stages that were involved in the x-ray amplification. It was conjectured, for example, that x-ray emissions from hole states in Cl-, K-, Ca-, and Ti-like xenon were being amplified. In this paper, our earlier xenon gain model (Petrova et al 2010 J. Phys. B: At. Mol. Opt. Phys. 43 025601) is extended to include single- and double-hole state production within the Fe-like ionization stage in addition to single-hole state production within the Co-like ionization stage in order to assess these conjectures. The gain model, based on flexible atomic code generated data (Gu 2008 Can. J. Phys. 86 675), includes Co-like and Fe-like hole-state generation in xenon through photoionization of 2s and 2p electrons. The hole-state dynamics is self-consistently coupled to an extensive collisional-radiative dynamics of the Ni-, Co-, and Fe-like ionization stages of xenon. In addition, the model includes tunnelling ionization rates that confirm the initial condition assumptions that were made in our earlier paper, and they are needed to support the interpretations of the measured broadband x-ray data. With the use of tunnelling ionization rates, we demonstrate how all of the N-shell, n = 4, electrons are striped from a xenon atom in less than a femtosecond at laser intensities larger than 10(19) W cm(-2). Our calculations also show that, under these initial conditions and with sufficiently high pumping rates (>= 10(14) s(-1)), a range of gains larger than 50 cm(-1) are achievable under select conditions from both Co- and Fe-like xenon single hole radiative decays, in conformity with experimental observations. However, the calculated gain coefficients are sensitive to the laser intensity, laser pulse risetime, the magnitude of the hole-state pumping rates, ion density, and electron and ion heating rates, and, in general, Co-like holes are found to have much higher gains than Fe-like hole states. These model calculations are also capable of producing gains from the double-hole states in Fe-like xenon, but they are much smaller than those generated in the Fe-like single-hole states in the cases included in this paper. Thus, our model calculations do not support the experimental data interpretation in which the measured gains were attributed to double holes in much higher ionization stages of xenon (Xe32+, Xe34+, Xe35+, and Xe37+). Our calculations suggest that these ionization stages can be reached either early in time at much higher laser intensities (in excess of 1.5 x 10(20) W cm(-2) for a 248 nm, similar to 230 fs pulse) or later in time, and only because of tunnelling ionization. In this latter case, however, the measured gains cannot be achieved since cluster densities have fallen by several orders of magnitude from their initial values and ion population have been spread over a much wider range of states. C1 [Petrova, Tz B.; Davis, J.] USN, Radiat Hydrodynam Branch, Div Plasma Phys, Res Lab, Washington, DC 20375 USA. [Whitney, K. G.] Berkeley Scholars Inc, Beltsville, MD 20705 USA. RP Petrova, TB (reprint author), USN, Radiat Hydrodynam Branch, Div Plasma Phys, Res Lab, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM lina.petrova@nrl.navy.mil FU DOE/NNSA; DARPA; NRL [6.1] FX The work is jointly supported by DOE/NNSA, by DARPA, and by NRL under the 6.1 program. We would like to thank Dr G Petrov for his valuable suggestions and comments. NR 15 TC 3 Z9 3 U1 2 U2 2 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0953-4075 J9 J PHYS B-AT MOL OPT JI J. Phys. B-At. Mol. Opt. Phys. PD JUN 28 PY 2011 VL 44 IS 12 AR 125601 DI 10.1088/0953-4075/44/12/125601 PG 18 WC Optics; Physics, Atomic, Molecular & Chemical SC Optics; Physics GA 774LE UT WOS:000291386600010 ER PT J AU Makinen, AJ Kushto, GP AF Maekinen, A. J. Kushto, G. P. TI Monolayer-induced band bending in the near-surface region of Ge(111) SO PHYSICAL REVIEW B LA English DT Article ID GERMANIUM; SILICON; FUNCTIONALIZATION; SI AB Directly grafted organic monolayers on Ge surfaces offer an interesting opportunity to explore aspects of surface passivation and control of electrical properties, namely, molecular gating, of semiconductor surfaces. We report our study of the interfacial electronic structures of n-type, intrinsic, and p-type Ge(111) surfaces that have been chemically modified with various organic monolayers. The monolayers investigated include octadecane, attached via hydrogermylation of 1-octadecene at Ge surfaces, as well as para-substituted phenyl rings, attached by diazonium activation of hydrogenated Ge surfaces. X-ray photoelectron spectroscopy measurements indicate that there is downward band bending, up to 160 meV, associated with assembling these organic monolayers on the Ge substrates. This band bending does not directly correlate with the dipole moment or electron withdrawing or donating character of the molecular moieties, pointing to the critical roles of the nature and quality of the self-assembled monolayer, and the intrinsic electronic structure of the semiconductor material in defining the interfacial electronic structure of the passivated Ge(111) surfaces. C1 [Maekinen, A. J.; Kushto, G. P.] USN, Res Lab, Washington, DC 20375 USA. RP Makinen, AJ (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM Antti.Makinen@nrl.navy.mil FU Office of Naval Research FX The authors would like to thank the Office of Naval Research for support of this work. NR 28 TC 2 Z9 2 U1 1 U2 21 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1098-0121 J9 PHYS REV B JI Phys. Rev. B PD JUN 27 PY 2011 VL 83 IS 24 AR 245315 DI 10.1103/PhysRevB.83.245315 PG 5 WC Physics, Condensed Matter SC Physics GA 784BO UT WOS:000292128800012 ER PT J AU Moody, G Siemens, ME Bristow, AD Dai, X Bracker, AS Gammon, D Cundiff, ST AF Moody, G. Siemens, M. E. Bristow, A. D. Dai, X. Bracker, A. S. Gammon, D. Cundiff, S. T. TI Exciton relaxation and coupling dynamics in a GaAs/AlxGa1-xAs quantum well and quantum dot ensemble SO PHYSICAL REVIEW B LA English DT Article ID CARRIER RELAXATION; SPIN RELAXATION; MU-M AB Exciton inter-and intra-actions in a GaAs/AlGaAs quantum well (QW) and quantum dot (QD) ensemble are studied using optical two-dimensional Fourier transform spectroscopy. We measure population dynamics for times up to 300 ps and temperatures up to 50 K and observe biexponential decay for both QW and QD excitons, strong QW -> QD relaxation, and weak QD -> QW activation. The population dynamics are modeled using a system of rate equations that incorporate radiative and nonradiative decay, coupling between bright and dark exciton states, and QW <-> QD coupling. The fast decay rates are attributed to exciton-bound hole spin flips between optically active and inactive states and are similar for the QW and QDs, indicating excitons are weakly localized in the QDs. The QW -> QD relaxation rate increases with temperature, and QD -> QW excitation is observed at temperatures >= 35 K. C1 [Moody, G.; Siemens, M. E.; Bristow, A. D.; Dai, X.; Cundiff, S. T.] Univ Colorado, JILA, Boulder, CO 80309 USA. [Moody, G.; Siemens, M. E.; Bristow, A. D.; Dai, X.; Cundiff, S. T.] NIST, Boulder, CO 80309 USA. [Moody, G.; Cundiff, S. T.] Univ Colorado, Dept Phys, Boulder, CO 80309 USA. [Bracker, A. S.; Gammon, D.] USN, Res Lab, Washington, DC 20375 USA. RP Moody, G (reprint author), Univ Colorado, JILA, Boulder, CO 80309 USA. EM cundiff@jila.colorado.edu RI Cundiff, Steven/B-4974-2009; Bristow, Alan/F-9703-2013; Moody, Galan/J-5811-2014; Dai, Xingcan/B-3556-2014 OI Cundiff, Steven/0000-0002-7119-5197; Moody, Galan/0000-0001-7263-1483; FU National Science Foundation; US Department of Energy, and the Chemical Sciences, Geosciences, and Biosciences Division, Office of Basic Energy Sciences; National Academy of Sciences/National Research Council FX This work was supported by the National Science Foundation, the US Department of Energy, and the Chemical Sciences, Geosciences, and Biosciences Division, Office of Basic Energy Sciences. MES acknowledges funding from the National Academy of Sciences/National Research Council. NR 33 TC 25 Z9 25 U1 1 U2 18 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1098-0121 J9 PHYS REV B JI Phys. Rev. B PD JUN 27 PY 2011 VL 83 IS 24 AR 245316 DI 10.1103/PhysRevB.83.245316 PG 7 WC Physics, Condensed Matter SC Physics GA 784BO UT WOS:000292128800013 ER PT J AU Aggarwal, MM Ahammed, Z Alakhverdyants, AV Alekseev, I Alford, J Anderson, BD Arkhipkin, D Averichev, GS Balewski, J Barnby, LS Baumgart, S Beavis, DR Bellwied, R Betancourt, MJ Betts, RR Bhasin, A Bhati, AK Bichsel, H Bielcik, J Bielcikova, J Biritz, B Bland, LC Bonner, BE Bouchet, J Braidot, E Brandin, AV Bridgeman, A Bruna, E Bueltmann, S Bunzarov, I Burton, TP Cai, XZ Caines, H Sanchez, MCDLB Catu, O Cebra, D Cendejas, R Cervantes, MC Chajecki, Z Chaloupka, P Chattopadhyay, S Chen, HF Chen, JH Chen, JY Cheng, J Cherney, M Chikanian, A Choi, KE Christie, W Chung, P Clarke, RF Codrington, MJM Corliss, R Cramer, JG Crawford, HJ Das, D Dash, S Leyva, AD De Silva, LC Debbe, RR Dedovich, TG Derevschikov, AA de Souza, RD Didenko, L Djawotho, P Dogra, SM Dong, X Drachenberg, JL Draper, JE Dunlop, JC Mazumdar, MRD Efimov, LG Elhalhuli, E Elnimr, M Engelage, J Eppley, G Erazmus, B Estienne, M Eun, L Evdokimov, O Fachini, P Fatemi, R Fedorisin, J Fersch, RG Filip, P Finch, E Fine, V Fisyak, Y Gagliardi, CA Gangadharan, DR Ganti, MS Garcia-Solis, EJ Geromitsos, A Geurts, F Ghazikhanian, V Ghosh, P Gorbunov, YN Gordon, A Grebenyuk, O Grosnick, D Guertin, SM Gupta, A Gupta, N Guryn, W Haag, B Hamed, A Han, LX Harris, JW Hays-Wehle, JP Heinz, M Heppelmann, S Hirsch, A Hjort, E Hoffman, AM Hoffmann, GW Hofman, DJ Huang, B Huang, HZ Humanic, TJ Huo, L Igo, G Jacobs, P Jacobs, WW Jena, C Jin, F Jones, CL Jones, PG Joseph, J Judd, EG Kabana, S Kajimoto, K Kang, K Kapitan, J Kauder, K Keane, D Kechechyan, A Kettler, D Kikola, DP Kiryluk, J Kisiel, A Klein, SR Knospe, AG Kocoloski, A Koetke, DD Kollegger, T Konzer, J Koralt, I Koroleva, L Korsch, W Kotchenda, L Kouchpil, V Kravtsov, P Krueger, K Krus, M Kumar, L Kurnadi, P Lamont, MAC Landgraf, JM LaPointe, S Lauret, J Lebedev, A Lednicky, R Lee, CH Lee, JH Leight, W LeVine, MJ Li, C Li, L Li, N Li, W Li, X Li, X Li, Y Li, ZM Lin, G Lindenbaum, SJ Lisa, MA Liu, F Liu, H Liu, J Ljubicic, T Llope, WJ Longacre, RS Love, WA Lu, Y Lukashov, EV Luo, X Ma, GL Ma, YG Mahapatra, DP Majka, R Mall, OI Mangotra, LK Manweiler, R Margetis, S Markert, C Masui, H Matis, HS Matulenko, YA McDonald, D McShane, TS Meschanin, A Milner, R Minaev, NG Mioduszewski, S Mischke, A Mitrovski, MK Mohanty, B Mondal, MM Morozov, B Morozov, DA Munhoz, MG Nandi, BK Nattrass, C Nayak, TK Nelson, JM Netrakanti, PK Ng, MJ Nogach, LV Nurushev, SB Odyniec, G Ogawa, A Okorokov, V Oldag, EW Olson, D Pachr, M Page, BS Pal, SK Pandit, Y Panebratsev, Y Pawlak, T Peitzmann, T Perevoztchikov, V Perkins, C Peryt, W Phatak, SC Pile, P Planinic, M Ploskon, MA Pluta, J Plyku, D Poljak, N Poskanzer, AM Potukuchi, BVKS Powell, CB Prindle, D Pruneau, C Pruthi, NK Pujahari, PR Putschke, J Qiu, H Raniwala, R Raniwala, S Ray, RL Redwine, R Reed, R Ritter, HG Roberts, JB Rogachevskiy, OV Romero, JL Rose, A Roy, C Ruan, L Sahoo, R Sakai, S Sakrejda, I Sakuma, T Salur, S Sandweiss, J Sangaline, E Schambach, J Scharenberg, RP Schmitz, N Schuster, TR Seele, J Seger, J Selyuzhenkov, I Seyboth, P Shahaliev, E Shao, M Sharma, M Shi, SS Sichtermann, EP Simon, F Singaraju, RN Skoby, MJ Smirnov, N Sorensen, P Sowinski, J Spinka, HM Srivastava, B Stanislaus, TDS Staszak, D Stevens, JR Stock, R Strikhanov, M Stringfellow, B Suaide, AAP Suarez, MC Subba, NL Sumbera, M Sun, XM Sun, Y Sun, Z Surrow, B Svirida, DN Symons, TJM de Toledo, AS Takahashi, J Tang, AH Tang, Z Tarini, LH Tarnowsky, T Thein, D Thomas, JH Tian, J Timmins, AR Timoshenko, S Tlusty, D Tokarev, M Trainor, TA Tram, VN Trentalange, S Tribble, RE Tsai, OD Ulery, J Ullrich, T Underwood, DG Van Buren, G van Leeuwen, M van Nieuwenhuizen, G Vanfossen, JA Varma, R Vasconcelos, GMS Vasiliev, AN Videbaek, F Viyogi, YP Vokal, S Voloshin, SA Wada, M Walker, M Wang, F Wang, G Wang, H Wang, JS Wang, Q Wang, XL Wang, Y Webb, G Webb, JC Westfall, GD Whitten, C Wieman, H Wissink, SW Witt, R Wu, YF Xie, W Xu, H Xu, N Xu, QH Xu, W Xu, Y Xu, Z Xue, L Yang, Y Yepes, P Yip, K Yoo, IK Yue, Q Zawisza, M Zbroszczyk, H Zhan, W Zhang, JB Zhang, S Zhang, WM Zhang, XP Zhang, Y Zhang, ZP Zhao, J Zhong, C Zhou, J Zhou, W Zhu, X Zhu, YH Zoulkarneev, R Zoulkarneeva, Y AF Aggarwal, M. M. Ahammed, Z. Alakhverdyants, A. V. Alekseev, I. Alford, J. Anderson, B. D. Arkhipkin, D. Averichev, G. S. Balewski, J. Barnby, L. S. Baumgart, S. Beavis, D. R. Bellwied, R. Betancourt, M. J. Betts, R. R. Bhasin, A. Bhati, A. K. Bichsel, H. Bielcik, J. Bielcikova, J. Biritz, B. Bland, L. C. Bonner, B. E. Bouchet, J. Braidot, E. Brandin, A. V. Bridgeman, A. Bruna, E. Bueltmann, S. Bunzarov, I. Burton, T. P. Cai, X. Z. Caines, H. de la Barca Sanchez, M. Calderon Catu, O. Cebra, D. Cendejas, R. Cervantes, M. C. Chajecki, Z. Chaloupka, P. Chattopadhyay, S. Chen, H. F. Chen, J. H. Chen, J. Y. Cheng, J. Cherney, M. Chikanian, A. Choi, K. E. Christie, W. Chung, P. Clarke, R. F. Codrington, M. J. M. Corliss, R. Cramer, J. G. Crawford, H. J. Das, D. Dash, S. Leyva, A. Davila De Silva, L. C. Debbe, R. R. Dedovich, T. G. Derevschikov, A. A. Derradi de Souza, R. Didenko, L. Djawotho, P. Dogra, S. M. Dong, X. Drachenberg, J. L. Draper, J. E. Dunlop, J. C. Mazumdar, M. R. Dutta Efimov, L. G. 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Krueger, K. Krus, M. Kumar, L. Kurnadi, P. Lamont, M. A. C. Landgraf, J. M. LaPointe, S. Lauret, J. Lebedev, A. Lednicky, R. Lee, C-H. Lee, J. H. Leight, W. LeVine, M. J. Li, C. Li, L. Li, N. Li, W. Li, X. Li, X. Li, Y. Li, Z. M. Lin, G. Lindenbaum, S. J. Lisa, M. A. Liu, F. Liu, H. Liu, J. Ljubicic, T. Llope, W. J. Longacre, R. S. Love, W. A. Lu, Y. Lukashov, E. V. Luo, X. Ma, G. L. Ma, Y. G. Mahapatra, D. P. Majka, R. Mall, O. I. Mangotra, L. K. Manweiler, R. Margetis, S. Markert, C. Masui, H. Matis, H. S. Matulenko, Yu. A. McDonald, D. McShane, T. S. Meschanin, A. Milner, R. Minaev, N. G. Mioduszewski, S. Mischke, A. Mitrovski, M. K. Mohanty, B. Mondal, M. M. Morozov, B. Morozov, D. A. Munhoz, M. G. Nandi, B. K. Nattrass, C. Nayak, T. K. Nelson, J. M. Netrakanti, P. K. Ng, M. J. Nogach, L. V. Nurushev, S. B. Odyniec, G. Ogawa, A. Okorokov, V. Oldag, E. W. Olson, D. Pachr, M. Page, B. S. Pal, S. K. Pandit, Y. Panebratsev, Y. Pawlak, T. Peitzmann, T. Perevoztchikov, V. Perkins, C. Peryt, W. Phatak, S. C. Pile, P. Planinic, M. Ploskon, M. A. Pluta, J. Plyku, D. Poljak, N. Poskanzer, A. M. Potukuchi, B. V. K. S. Powell, C. B. Prindle, D. Pruneau, C. Pruthi, N. K. Pujahari, P. R. Putschke, J. Qiu, H. Raniwala, R. Raniwala, S. Ray, R. L. Redwine, R. Reed, R. Ritter, H. G. Roberts, J. B. Rogachevskiy, O. V. Romero, J. L. Rose, A. Roy, C. Ruan, L. Sahoo, R. Sakai, S. Sakrejda, I. Sakuma, T. Salur, S. Sandweiss, J. Sangaline, E. Schambach, J. Scharenberg, R. P. Schmitz, N. Schuster, T. R. Seele, J. Seger, J. Selyuzhenkov, I. Seyboth, P. Shahaliev, E. Shao, M. Sharma, M. Shi, S. S. Sichtermann, E. P. Simon, F. Singaraju, R. N. Skoby, M. J. Smirnov, N. Sorensen, P. Sowinski, J. Spinka, H. M. Srivastava, B. Stanislaus, T. D. S. Staszak, D. Stevens, J. R. Stock, R. Strikhanov, M. Stringfellow, B. Suaide, A. A. P. Suarez, M. C. Subba, N. L. Sumbera, M. Sun, X. M. Sun, Y. Sun, Z. Surrow, B. Svirida, D. N. Symons, T. J. M. Szanto de Toledo, A. Takahashi, J. Tang, A. H. Tang, Z. Tarini, L. H. Tarnowsky, T. Thein, D. Thomas, J. H. Tian, J. Timmins, A. R. Timoshenko, S. Tlusty, D. Tokarev, M. Trainor, T. A. Tram, V. N. Trentalange, S. Tribble, R. E. Tsai, O. D. Ulery, J. Ullrich, T. Underwood, D. G. Van Buren, G. van Leeuwen, M. van Nieuwenhuizen, G. Vanfossen, J. A., Jr. Varma, R. Vasconcelos, G. M. S. Vasiliev, A. N. Videbaek, F. Viyogi, Y. P. Vokal, S. Voloshin, S. A. Wada, M. Walker, M. Wang, F. Wang, G. Wang, H. Wang, J. S. Wang, Q. Wang, X. L. Wang, Y. Webb, G. Webb, J. C. Westfall, G. D. Whitten, C., Jr. Wieman, H. Wissink, S. W. Witt, R. Wu, Y. F. Xie, W. Xu, H. Xu, N. Xu, Q. H. Xu, W. Xu, Y. Xu, Z. Xue, L. Yang, Y. Yepes, P. Yip, K. Yoo, I-K. Yue, Q. Zawisza, M. Zbroszczyk, H. Zhan, W. Zhang, J. B. Zhang, S. Zhang, W. M. Zhang, X. P. Zhang, Y. Zhang, Z. P. Zhao, J. Zhong, C. Zhou, J. Zhou, W. Zhu, X. Zhu, Y. H. Zoulkarneev, R. Zoulkarneeva, Y. CA STAR Collaboration TI Pion femtoscopy in p plus p collisions at root s=200 GeV SO PHYSICAL REVIEW C LA English DT Article ID BOSE-EINSTEIN CORRELATIONS; HEAVY-ION COLLISIONS; QUARK-GLUON PLASMA; AVERAGE TRANSVERSE-MOMENTUM; HADRONIC Z-DECAYS; PARTICLE CORRELATIONS; COULOMB CORRECTIONS; CHARGED PIONS; SOURCE SIZE; 1.8 TEV AB The STAR Collaboration at the BNL Relativistic Heavy Ion Collider has measured two-pion correlation functions from p + p collisions at root s = 200 GeV. Spatial scales are extracted via a femtoscopic analysis of the correlations, though this analysis is complicated by the presence of strong nonfemtoscopic effects. Our results are put into the context of the world data set of femtoscopy in hadron-hadron collisions. We present the first direct comparison of femtoscopy in p + p and heavy ion collisions, under identical analysis and detector conditions. C1 [Bridgeman, A.; Krueger, K.; Spinka, H. M.; Underwood, D. G.] Argonne Natl Lab, Argonne, IL 60439 USA. [Barnby, L. S.; Elhalhuli, E.; Jones, P. G.; Nelson, J. M.] Univ Birmingham, Birmingham, W Midlands, England. [Arkhipkin, D.; Beavis, D. R.; Bland, L. C.; Burton, T. P.; Christie, W.; Debbe, R. R.; Didenko, L.; Dunlop, J. C.; Fachini, P.; Fine, V.; Fisyak, Y.; Gordon, A.; Guryn, W.; Lamont, M. A. C.; Landgraf, J. M.; Lauret, J.; Lebedev, A.; Lee, J. H.; LeVine, M. J.; Ljubicic, T.; Longacre, R. S.; Love, W. A.; Ogawa, A.; Perevoztchikov, V.; Pile, P.; Ruan, L.; Sorensen, P.; Tang, A. H.; Ullrich, T.; Van Buren, G.; Videbaek, F.; Webb, J. C.; Xu, Z.; Yip, K.] Brookhaven Natl Lab, Upton, NY 11973 USA. [Crawford, H. J.; Engelage, J.; Judd, E. G.; Ng, M. J.; Perkins, C.] Univ Calif Berkeley, Berkeley, CA 94720 USA. [de la Barca Sanchez, M. Calderon; Cebra, D.; Das, D.; Draper, J. E.; Haag, B.; Liu, H.; Mall, O. I.; Reed, R.; Romero, J. L.; Salur, S.; Sangaline, E.] Univ Calif Davis, Davis, CA 95616 USA. [Biritz, B.; Cendejas, R.; Gangadharan, D. R.; Ghazikhanian, V.; Guertin, S. M.; Huang, H. Z.; Igo, G.; Kurnadi, P.; Sakai, S.; Staszak, D.; Trentalange, S.; Tsai, O. D.; Wang, G.; Whitten, C., Jr.; Xu, W.] Univ Calif Los Angeles, Los Angeles, CA 90095 USA. [Derradi de Souza, R.; Takahashi, J.; Vasconcelos, G. M. S.] Univ Estadual Campinas, Sao Paulo, Brazil. [Betts, R. R.; Evdokimov, O.; Garcia-Solis, E. J.; Hofman, D. J.; Kauder, K.; Suarez, M. C.] Univ Illinois, Chicago, IL 60607 USA. [Cherney, M.; Gorbunov, Y. N.; McShane, T. S.; Seger, J.] Creighton Univ, Omaha, NE 68178 USA. [Bielcik, J.; Krus, M.; Pachr, M.] Czech Tech Univ, Fac Nucl Sci & Phys Engn, CR-11519 Prague, Czech Republic. [Bielcikova, J.; Chaloupka, P.; Chung, P.; Kapitan, J.; Kouchpil, V.; Sumbera, M.; Tlusty, D.] Nucl Phys Inst AS CR, Rez 25068, Czech Republic. [Kollegger, T.; Mitrovski, M. K.; Schuster, T. R.; Stock, R.] Goethe Univ Frankfurt, Frankfurt, Germany. [Dash, S.; Jena, C.; Mahapatra, D. P.; Phatak, S. C.] Inst Phys, Bhubaneswar 751005, Orissa, India. [Nandi, B. K.; Pujahari, P. R.; Varma, R.] Indian Inst Technol, Mumbai 400076, Maharashtra, India. [Jacobs, W. W.; Page, B. S.; Selyuzhenkov, I.; Sowinski, J.; Stevens, J. R.; Wissink, S. W.] Indiana Univ, Bloomington, IN 47408 USA. [Alekseev, I.; Koroleva, L.; Morozov, B.; Svirida, D. N.] Alikhanov Inst Theoret & Expt Phys, Moscow, Russia. [Bhasin, A.; Dogra, S. M.; Gupta, A.; Gupta, N.; Mangotra, L. K.; Potukuchi, B. V. K. S.] Univ Jammu, Jammu 180001, India. [Alakhverdyants, A. V.; Averichev, G. S.; Bunzarov, I.; Dedovich, T. G.; Efimov, L. G.; Fedorisin, J.; Filip, P.; Kechechyan, A.; Lednicky, R.; Panebratsev, Y.; Rogachevskiy, O. V.; Shahaliev, E.; Tokarev, M.; Vokal, S.; Zoulkarneev, R.; Zoulkarneeva, Y.] Joint Inst Nucl Res, Dubna 141980, Russia. [Alford, J.; Anderson, B. D.; Bouchet, J.; Joseph, J.; Keane, D.; Kumar, L.; Margetis, S.; Pandit, Y.; Subba, N. L.; Vanfossen, J. A., Jr.; Zhang, W. M.] Kent State Univ, Kent, OH 44242 USA. [Fatemi, R.; Fersch, R. 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[Erazmus, B.; Estienne, M.; Geromitsos, A.; Kabana, S.; Roy, C.; Sahoo, R.] SUBATECH, Nantes, France. [Cervantes, M. C.; Clarke, R. F.; Codrington, M. J. M.; Djawotho, P.; Drachenberg, J. L.; Gagliardi, C. A.; Hamed, A.; Huo, L.; Mioduszewski, S.; Tribble, R. E.] Texas A&M Univ, College Stn, TX 77843 USA. [Leyva, A. Davila; Hoffmann, G. W.; Kajimoto, K.; Li, L.; Markert, C.; Oldag, E. W.; Ray, R. L.; Schambach, J.; Thein, D.; Wada, M.] Univ Texas Austin, Austin, TX 78712 USA. [Cheng, J.; Kang, K.; Li, Y.; Wang, Y.; Yue, Q.; Zhu, X.] Tsinghua Univ, Beijing 100084, Peoples R China. [Witt, R.] USN Acad, Annapolis, MD 21402 USA. [Grosnick, D.; Koetke, D. D.; Manweiler, R.; Stanislaus, T. D. S.] Valparaiso Univ, Valparaiso, IN 46383 USA. [Chattopadhyay, S.; Mazumdar, M. R. Dutta; Ganti, M. S.; Ghosh, P.; Mohanty, B.; Mondal, M. M.; Nayak, T. K.; Pal, S. K.; Singaraju, R. N.; Viyogi, Y. P.] Bhabha Atom Res Ctr, Ctr Variable Energy Cyclotron, Kolkata 700064, W Bengal, India. [Kisiel, A.; Pawlak, T.; Peryt, W.; Pluta, J.; Zawisza, M.; Zbroszczyk, H.] Warsaw Univ Technol, Warsaw, Poland. [Bichsel, H.; Cramer, J. G.; Kettler, D.; Prindle, D.; Trainor, T. A.] Univ Washington, Seattle, WA 98195 USA. [Bellwied, R.; De Silva, L. C.; Elnimr, M.; LaPointe, S.; Pruneau, C.; Sharma, M.; Tarini, L. H.; Timmins, A. R.; Voloshin, S. A.] Wayne State Univ, Detroit, MI 48201 USA. [Chen, J. Y.; Li, N.; Li, Z. M.; Liu, F.; Shi, S. S.; Wu, Y. F.; Zhang, J. B.] CCNU HZNU, Inst Particle Phys, Wuhan 430079, Peoples R China. [Baumgart, S.; Bruna, E.; Caines, H.; Catu, O.; Chikanian, A.; Finch, E.; Harris, J. W.; Heinz, M.; Knospe, A. G.; Lin, G.; Majka, R.; Nattrass, C.; Putschke, J.; Sandweiss, J.; Smirnov, N.] Yale Univ, New Haven, CT 06520 USA. [Planinic, M.; Poljak, N.] Univ Zagreb, HR-10002 Zagreb, Croatia. [Aggarwal, M. M.; Bhati, A. K.] Panjab Univ, Chandigarh 160014, India. RP Aggarwal, MM (reprint author), Panjab Univ, Chandigarh 160014, India. RI Inst. of Physics, Gleb Wataghin/A-9780-2017; Okorokov, Vitaly/C-4800-2017; Ma, Yu-Gang/M-8122-2013; Lednicky, Richard/K-4164-2013; Barnby, Lee/G-2135-2010; Mischke, Andre/D-3614-2011; Takahashi, Jun/B-2946-2012; Planinic, Mirko/E-8085-2012; Yang, Yanyun/B-9485-2014; Yoo, In-Kwon/J-6222-2012; Peitzmann, Thomas/K-2206-2012; Witt, Richard/H-3560-2012; Yip, Kin/D-6860-2013; Xue, Liang/F-8077-2013; Voloshin, Sergei/I-4122-2013; Pandit, Yadav/I-2170-2013; Bielcikova, Jana/G-9342-2014; Alekseev, Igor/J-8070-2014; Sumbera, Michal/O-7497-2014; Strikhanov, Mikhail/P-7393-2014; Xu, Wenqin/H-7553-2014; Lee, Chang-Hwan/B-3096-2015; Bruna, Elena/C-4939-2014; Dogra, Sunil /B-5330-2013; Chaloupka, Petr/E-5965-2012; Huang, Bingchu/H-6343-2015; Nattrass, Christine/J-6752-2016; Derradi de Souza, Rafael/M-4791-2013; Suaide, Alexandre/L-6239-2016; Svirida, Dmitry/R-4909-2016 OI Okorokov, Vitaly/0000-0002-7162-5345; Ma, Yu-Gang/0000-0002-0233-9900; Barnby, Lee/0000-0001-7357-9904; Takahashi, Jun/0000-0002-4091-1779; Yang, Yanyun/0000-0002-5982-1706; Peitzmann, Thomas/0000-0002-7116-899X; Yip, Kin/0000-0002-8576-4311; Xue, Liang/0000-0002-2321-9019; Pandit, Yadav/0000-0003-2809-7943; Alekseev, Igor/0000-0003-3358-9635; Sumbera, Michal/0000-0002-0639-7323; Strikhanov, Mikhail/0000-0003-2586-0405; Xu, Wenqin/0000-0002-5976-4991; Lee, Chang-Hwan/0000-0003-3221-1171; Bruna, Elena/0000-0001-5427-1461; Huang, Bingchu/0000-0002-3253-3210; Nattrass, Christine/0000-0002-8768-6468; Derradi de Souza, Rafael/0000-0002-2084-7001; Suaide, Alexandre/0000-0003-2847-6556; FU Offices of NP and HEP within the US DOE Office of Science; US NSF; Sloan Foundation; DFG cluster of excellence 'Origin and Structure of the Universe' of Germany [CNRS/IN2P3]; STFC; EPSRC of the United Kingdom; FAPESP CNPq of Brazil; Ministry of Ed. and Sci. of the Russian Federation; NNSFC; CAS; MoST; MoE of China; GA and MSMT of the Czech Republic; FOM and NWO of the Netherlands; DAE; DST; CSIR of India; Polish Ministry of Sci. and Higher Ed.; Korea Research Foundation; Ministry of Sci., Ed. and Sports of the Republic of Croatia; RosAtom of Russia FX We thank the RHIC Operations Group and RCF at BNL, the NERSC Center at LBNL, and the Open Science Grid consortium for providing resources and support. This work was supported in part by the Offices of NP and HEP within the US DOE Office of Science, the US NSF, the Sloan Foundation, the DFG cluster of excellence 'Origin and Structure of the Universe' of Germany, CNRS/IN2P3, STFC and EPSRC of the United Kingdom, FAPESP CNPq of Brazil, Ministry of Ed. and Sci. of the Russian Federation, NNSFC, CAS, MoST, and MoE of China, GA and MSMT of the Czech Republic, FOM and NWO of the Netherlands, DAE, DST, and CSIR of India, Polish Ministry of Sci. and Higher Ed., Korea Research Foundation, Ministry of Sci., Ed. and Sports of the Republic of Croatia, and RosAtom of Russia. NR 88 TC 29 Z9 30 U1 0 U2 15 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 2469-9985 EI 2469-9993 J9 PHYS REV C JI Phys. Rev. C PD JUN 27 PY 2011 VL 83 IS 6 AR 064905 DI 10.1103/PhysRevC.83.064905 PG 17 WC Physics, Nuclear SC Physics GA 783WK UT WOS:000292114600006 ER PT J AU Su, JQ Nelson, TW McNelley, TR Mishra, RS AF Su, Jian-Qing Nelson, T. W. McNelley, T. R. Mishra, R. S. TI Development of nanocrystalline structure in Cu during friction stir processing (FSP) SO MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING LA English DT Article DE Friction stir processing (FSP); Orientation imaging microscopy (OIM); Grain refinement; Nanocrystalline structure; Microband ID STRENGTH ALUMINUM-ALLOYS; DYNAMIC RECRYSTALLIZATION; POLYCRYSTALLINE COPPER; DEFORMED METALS; STRAIN-RATE; GRAIN-SIZE; DEFORMATION; MICROSTRUCTURE; EVOLUTION; DISLOCATIONS AB The characteristics of microstructures at various locations behind the pin tool extraction site were studied in copper after FSP that had been conducted with continuous quenching to enhance cooling rates. The substructures initially formed around the pin tool consist of very small crystallites having sizes of a few tens of nanometers. It is proposed that the processing conditions result in formation of microband structures around pin tool in the presence of severe strain heterogeneity. The microbands appear as nanoscale elongated crystallites surrounded by high-angle boundaries. The elongated crystallites transform to nearly random oriented and equiaxed grain structures by shape adjustment during the initial stages of cooling from the peak temperature. Nanocrystalline structures similar to 174 nm in size were produced in OFHC copper by FSP. (C) 2011 Elsevier B.V. All rights reserved. C1 [Mishra, R. S.] Missouri Univ Sci & Technol, Dept Mat Sci & Engn, Rolla, MO 65409 USA. [Su, Jian-Qing; McNelley, T. R.] USN, Postgrad Sch, Dept Mech & Astronaut Engn, Monterey, CA 93943 USA. [Nelson, T. W.] Brigham Young Univ, Dept Mech Engn, Provo, UT 84604 USA. RP Su, JQ (reprint author), Missouri Univ Sci & Technol, Dept Mat Sci & Engn, Rolla, MO 65409 USA. EM jsu@mst.edu RI Mishra, Rajiv/A-7985-2009 OI Mishra, Rajiv/0000-0002-1699-0614 FU US National Research Council (NRC); Office of Naval Research [N00014-09-WR20201] FX J.Q. Su would like to acknowledge the support of the US National Research Council (NRC) Research Associateship program. The authors acknowledge partial support by the Office of Naval Research under contract number N00014-09-WR20201, with Drs. J. Deloach and R. Fonda as Scientific Officers. NR 49 TC 27 Z9 28 U1 2 U2 13 PU ELSEVIER SCIENCE SA PI LAUSANNE PA PO BOX 564, 1001 LAUSANNE, SWITZERLAND SN 0921-5093 J9 MAT SCI ENG A-STRUCT JI Mater. Sci. Eng. A-Struct. Mater. Prop. Microstruct. Process. PD JUN 25 PY 2011 VL 528 IS 16-17 BP 5458 EP 5464 DI 10.1016/j.msea.2011.03.043 PG 7 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering SC Science & Technology - Other Topics; Materials Science; Metallurgy & Metallurgical Engineering GA 774GM UT WOS:000291373600019 ER PT J AU Keller, JH Jones, SC Evans, JL Harr, PA AF Keller, J. H. Jones, S. C. Evans, J. L. Harr, P. A. TI Characteristics of the TIGGE multimodel ensemble prediction system in representing forecast variability associated with extratropical transition SO GEOPHYSICAL RESEARCH LETTERS LA English DT Article ID WESTERN NORTH PACIFIC; TROPICAL CYCLONES; DOWNSTREAM IMPACTS; SENSITIVITY AB The characteristics of the extratropical transition (ET) of tropical cyclones and its impact on the midlatitude flow are examined in the THORPEX Interactive Grand Global Ensemble (TIGGE) multimodel ensemble prediction system (EPS). Ten ensemble forecasts initialized prior to ET for five tropical cyclones in 2008 are investigated using an empirical orthogonal function analysis and fuzzy clustering methodology. Each forecast contains 231 members from eight different global EPS. The EPS contributing to TIGGE differ in their spread and their contributions to the different scenarios. Some of the individual EPS are generally confined to only a few scenarios, whereas others contribute regularly to almost all. TIGGE contains more development scenarios than European Centre for Medium Range Weather Forecast (ECMWF) EPS but the full range of development scenarios is only found with the ECMWF included in the multimodel EPS. Citation: Keller, J. H., S. C. Jones, J. L. Evans, and P. A. Harr (2011), Characteristics of the TIGGE multimodel ensemble prediction system in representing forecast variability associated with extratropical transition, Geophys. Res. Lett., 38, L12802, doi:10.1029/2011GL047275. C1 [Keller, J. H.; Jones, S. C.] Karlsruhe Inst Technol, Inst Meteorol & Climate Res IMK TRO, D-76131 Karlsruhe, Germany. [Evans, J. L.] Penn State Univ, Dept Meteorol, University Pk, PA 16802 USA. [Harr, P. A.] USN, Postgrad Sch, Dept Meteorol, Monterey, CA 93943 USA. RP Keller, JH (reprint author), Karlsruhe Inst Technol, Inst Meteorol & Climate Res IMK TRO, Kaiserstr 12, D-76131 Karlsruhe, Germany. EM julia.keller@kit.edu; sarah.jones@kit.edu; evans@meteo.psu.edu; paharr@nps.edu RI Jones, Sarah/B-2339-2013 FU German Research Council (DFG) as part of the research unit PANDOWAE [FOR896]; National Science Foundation [ATM-0735973, AGS-0736003]; Karlsruhe House of Young Scientists; Office for Naval Research FX This study is part of Julia Keller's Ph.D. thesis supported by the German Research Council (DFG) as part of the research unit PANDOWAE (FOR896). The National Science Foundation supported the contribution of Jenni Evans under grant ATM-0735973 and Patrick Harr under grant AGS-0736003. Travel funding from the Karlsruhe House of Young Scientists and the Office for Naval Research Global Visiting for Julia Keller and Sarah Jones facilitated the collaboration. The authors thank the THORPEX consortium and the contributing centers for providing and maintaining the TIGGE database and Francesca Chiaromonte and Simon Lang for valuable discussions. NR 13 TC 19 Z9 19 U1 0 U2 5 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 0094-8276 J9 GEOPHYS RES LETT JI Geophys. Res. Lett. PD JUN 22 PY 2011 VL 38 AR L12802 DI 10.1029/2011GL047275 PG 6 WC Geosciences, Multidisciplinary SC Geology GA 783TN UT WOS:000292107000001 ER PT J AU Chen, W AF Chen, Wei TI Nonlinear inverse model for velocity estimation from an image sequence SO JOURNAL OF GEOPHYSICAL RESEARCH-OCEANS LA English DT Article ID ADVECTIVE SURFACE VELOCITIES; CROSS-CORRELATION TECHNIQUE; OPTICAL-FLOW; SATELLITE IMAGERY; INFRARED IMAGES; SEA; CURRENTS; OCEAN; TEMPERATURE; FIELDS AB Velocity estimation from an image sequence is one of the most challenging inverse problems in computer vision, geosciences, and remote sensing applications. In this paper a nonlinear model has been created for estimating motion field under the constraint of conservation of intensity. A linear differential form of heat or optical flow equation is replaced by a nonlinear temporal integral form of the intensity conservation constraint equation. Iterative equations with Gauss-Newton and Levenberg-Marguardt algorithms are formulated based on the nonlinear equations, velocity field modeling, and a nonlinear least squares model. An algorithm with progressive relaxation of the overconstraint to improve the performance of the velocity estimation is also proposed. The new estimator is benchmarked using a numerical simulation model. Both angular and magnitude error measurements based on the synthetic surface heat flow from the numerical model demonstrate that the performance of the new approach with the nonlinear model is much better than the results of using a linear model of heat or optical flow equation. Four sequences of NOAA Advanced Very High Resolution Radiometer (AVHRR) images taken in the New York Bight fields is also used to demonstrate the performance of the nonlinear inverse model, and the estimated velocity fields are compared with those measured with the Coastal Ocean Dynamics Radar array. The experimental results indicate that the nonlinear inverse model provides significant improvement over the linear inverse model for real AVHRR data sets. C1 USN, Remote Sensing Div, Res Lab, Washington, DC 20375 USA. RP Chen, W (reprint author), USN, Remote Sensing Div, Res Lab, Code 7233,4555 Overlook Ave, Washington, DC 20375 USA. EM wei.chen@nrl.navy.mil FU Office of Naval Research through Naval Research Laboratory [WU-4279-01] FX This research work was supported by the Office of Naval Research through the project WU-4279-01 at the Naval Research Laboratory. I am grateful to J. Kohut (Rutgers University) for supplying the CODAR velocity field used in this work. NR 36 TC 7 Z9 7 U1 0 U2 3 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 0148-0227 J9 J GEOPHYS RES-OCEANS JI J. Geophys. Res.-Oceans PD JUN 22 PY 2011 VL 116 AR C06015 DI 10.1029/2010JC006924 PG 14 WC Oceanography SC Oceanography GA 783VV UT WOS:000292113000001 ER PT J AU Susumu, K Oh, E Delehanty, JB Blanco-Canosa, JB Johnson, BJ Jain, V Hervey, WJ Algar, WR Boeneman, K Dawson, PE Medintz, IL AF Susumu, Kimihiro Oh, Eunkeu Delehanty, James B. Blanco-Canosa, Juan B. Johnson, Brandy J. Jain, Vaibhav Hervey, William Judson Algar, W. Russ Boeneman, Kelly Dawson, Philip E. Medintz, Igor L. TI Multifunctional Compact Zwitterionic Ligands for Preparing Robust Biocompatible Semiconductor Quantum Dots and Gold Nanoparticles SO JOURNAL OF THE AMERICAN CHEMICAL SOCIETY LA English DT Article ID RESONANCE ENERGY-TRANSFER; POLYETHYLENE-GLYCOL; SURFACE-COATINGS; DRUG-DELIVERY; STABILITY; CELL; NANOCRYSTALS; PROTEIN; MULTIVALENT; PEPTIDES AB We describe the synthesis of a series of four different ligands which are used to prepare hydrophilic, biocompatible luminescent quantum dots (QDs) and gold nanoparticles (AuNPs). Overall, the ligands are designed to be compact while still imparting a zwitterionic character to the NPs. Ligands are synthesized appended to a bidentate dihydrolipoic acid- (DHLA) anchor group, allowing for high-affinity NP attachment, and simultaneously incorporate tertiary amines along with carboxyl and/or hydroxyl groups. These are placed in close proximity within the ligand structure and their capacity for joint ionization imparts the requisite zwitterionic nature to the nanocrystal. QDs functionalized with the four different compact ligands were subjected to extensive physical characterization including surface charge, wettability, hydrodynamic size, and tolerance to a wide pH range or high salt concentration over time. The utility of the compact ligand coated QDs was further examined by testing of direct conjugation to polyhistidine-appended protein and peptides, aqueous covalent-coupling chemistry, and the ability to engage in Forster resonance energy transfer (FRET). Conjugating cell penetrating peptides to the compact ligand coated QD series facilitated their rapid and efficient cellular uptake, while subsequent cytotoxicity tests showed no apparent decreases in cell viability. In vivo biocompatibility was also demonstrated by microinjecting the compact ligand coated QDs into cells and monitoring their stability over time. Inherent benefits of the ligand design could be extended beyond QDs as AuNPs functionalized with the same compact ligand series showed similar colloidal properties. The strong potential of these ligands to expand NP capabilities in many biological applications is highlighted. C1 [Susumu, Kimihiro; Oh, Eunkeu; Jain, Vaibhav] USN, Res Lab, Div Opt Sci, Washington, DC 20375 USA. [Delehanty, James B.; Johnson, Brandy J.; Hervey, William Judson; Algar, W. Russ; Boeneman, Kelly; Medintz, Igor L.] USN, Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. [Blanco-Canosa, Juan B.; Dawson, Philip E.] Scripps Res Inst, Dept Cell Biol & Chem, La Jolla, CA 92037 USA. [Algar, W. Russ] George Mason Univ, Coll Sci, Fairfax, VA 22030 USA. RP Susumu, K (reprint author), USN, Res Lab, Div Opt Sci, Code 5611, Washington, DC 20375 USA. EM susumu@ccs.nrl.navy.mil; lgor.Medintz@nrl.navy.mil RI Johnson, Brandy/B-3462-2008; Gemmill, Kelly/G-2167-2012 OI Johnson, Brandy/0000-0002-3637-0631; FU NRL; NRL NSI; DARPA; ONR; ARO/DTRA; NRC RAP; Natural Sciences and Engineering Research Council of Canada (NSERC) FX The authors acknowledge NRL, the NRL NSI, DARPA, ONR, and ARO/DTRA for financial support. J.B.B.-C. acknowledges a Marie Curie IOF. W.J.H. gratefully acknowledges the NRC RAP postdoctoral fellowship program. W.R.A. is grateful to the Natural Sciences and Engineering Research Council of Canada (NSERC) for a postdoctoral fellowship. We thank Dr. M. Mauro at Life Technologies for providing a sample of custom Qdot 625 ITK organic QDs and S. MacDonald at ACD for assistance with pKa determinations. NR 79 TC 131 Z9 132 U1 10 U2 135 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0002-7863 J9 J AM CHEM SOC JI J. Am. Chem. Soc. PD JUN 22 PY 2011 VL 133 IS 24 BP 9480 EP 9496 DI 10.1021/ja201919s PG 17 WC Chemistry, Multidisciplinary SC Chemistry GA 781FD UT WOS:000291915100062 PM 21612225 ER PT J AU Fragiadakis, D Bokobza, L Pissis, P AF Fragiadakis, Daniel Bokobza, Liliane Pissis, Polycarpos TI Dynamics near the filler surface in natural rubber-silica nanocomposites SO POLYMER LA English DT Article DE Nanocomposite; Glass transition; Molecular dynamics ID GLASS-TRANSITION; IN-SITU; POLYMER NANOCOMPOSITES; MOLECULAR-DYNAMICS; DIELECTRIC-SPECTROSCOPY; TEMPERATURE-DEPENDENCE; POLY(VINYL ACETATE); IMMOBILIZED POLYMER; SEGMENTAL DYNAMICS; REINFORCEMENT AB We study the effect of in situ synthesized 10 nm silica nanoparticles on the glass transition and dynamics of natural rubber networks using differential scanning calorimetry, broadband dielectric relaxation spectroscopy and thermally stimulated depolarization currents. Even in the absence of specific polymer-filler interactions, polymer segments within a few nanometers of the filler particles exhibit relaxation times up to 2-3 orders of magnitude slower and reduced heat capacity increment at the glass transition compared to bulk natural rubber. These effects are only observed when the nanoparticles are uniformly distributed in the polymer matrix. (C) 2011 Elsevier Ltd. All rights reserved. C1 [Fragiadakis, Daniel; Pissis, Polycarpos] Natl Tech Univ Athens, Dept Phys, Athens 15780, Greece. [Bokobza, Liliane] ESPCI, Lab PPMD, F-75231 Paris, France. RP Fragiadakis, D (reprint author), USN, Res Lab, Div Chem, Code 6120, Washington, DC 20375 USA. EM daniel.fragiadakis.ctr@nrl.navy.mil RI Fragiadakis, Daniel/A-4510-2009 NR 49 TC 63 Z9 66 U1 9 U2 65 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0032-3861 EI 1873-2291 J9 POLYMER JI Polymer PD JUN 22 PY 2011 VL 52 IS 14 BP 3175 EP 3182 DI 10.1016/j.polymer.2011.04.045 PG 8 WC Polymer Science SC Polymer Science GA 783CR UT WOS:000292059600023 ER PT J AU Abdo, AA Ackermann, M Ajello, M Baldini, L Ballet, J Barbiellini, G Baring, MG Bastieri, D Bechtol, K Bellazzini, R Berenji, B Bhat, PN Bissaldi, E Blandford, RD Bonamente, E Bonnell, J Borgland, AW Bouvier, A Bregeon, J Brigida, M Bruel, P Buehler, R Buson, S Caliandro, GA Cameron, RA Caraveo, PA Casandjian, JM Cecchi, C Charles, E Chekhtman, A Chiang, J Ciprini, S Claus, R Connaughton, V Conrad, J Cutini, S de Angelis, A de Palma, F Dermer, CD Silva, EDE Drell, PS Dubois, R Favuzzi, C Fukazawa, Y Fusco, P Gargano, F Gehrels, N Germani, S Giglietto, N Giommi, P Giordano, F Giroletti, M Glanzman, T Godfrey, G Granot, J Grenier, IA Guiriec, S Hadasch, D Hanabata, Y Hughes, RE Johannesson, G Johnson, AS Kamae, T Katagiri, H Kataoka, J Kerr, M Knodlseder, J Kuss, M Lande, J Latronico, L Lee, SH Longo, F Loparco, F Lott, B Lubrano, P Mazziotta, MN McEnery, JE Meszaros, P Michelson, PF Mizuno, T Moiseev, AA Monzani, ME Morselli, A Moskalenko, IV Murgia, S Nakamori, T Naumann-Godo, M Nolan, PL Norris, JP Nuss, E Ohsugi, T Okumura, A Omodei, N Orlando, E Paciesas, WS Pelassa, V Pesce-Rollins, M Pierbattista, M Piron, F Porter, TA Racusin, JL Raino, S Razzano, M Razzaque, S Reimer, A Reimer, O Reyes, LC Roth, M Sadrozinski, HFW Sgro, C Siskind, EJ Smith, PD Sonbas, E Spandre, G Spinelli, P Stamatikos, M Strickman, MS Takahashi, H Tanaka, T Tanaka, Y Thayer, JG Thayer, JB Torres, DF Tosti, G Troja, E Uehara, T Usher, TL Vandenbroucke, J Vasileiou, V Vianello, G Vilchez, N Vitale, V von Kienlin, A Waite, AP Wang, P Winer, BL Wood, KS Yamazaki, R Yang, Z Ziegler, M Piro, L AF Abdo, A. A. Ackermann, M. Ajello, M. Baldini, L. Ballet, J. Barbiellini, G. Baring, M. G. Bastieri, D. Bechtol, K. Bellazzini, R. Berenji, B. Bhat, P. N. Bissaldi, E. Blandford, R. D. Bonamente, E. Bonnell, J. Borgland, A. W. Bouvier, A. Bregeon, J. Brigida, M. Bruel, P. Buehler, R. Buson, S. Caliandro, G. A. Cameron, R. A. Caraveo, P. A. Casandjian, J. M. Cecchi, C. Charles, E. Chekhtman, A. Chiang, J. Ciprini, S. Claus, R. Connaughton, V. Conrad, J. Cutini, S. de Angelis, A. de Palma, F. Dermer, C. D. do Couto e Silva, E. Drell, P. S. Dubois, R. Favuzzi, C. Fukazawa, Y. Fusco, P. Gargano, F. Gehrels, N. Germani, S. Giglietto, N. Giommi, P. Giordano, F. Giroletti, M. Glanzman, T. Godfrey, G. Granot, J. Grenier, I. A. Guiriec, S. Hadasch, D. Hanabata, Y. Hughes, R. E. Johannesson, G. Johnson, A. S. Kamae, T. Katagiri, H. Kataoka, J. Kerr, M. Knoedlseder, J. Kuss, M. Lande, J. Latronico, L. Lee, S. -H. Longo, F. Loparco, F. Lott, B. Lubrano, P. Mazziotta, M. N. McEnery, J. E. Meszaros, P. Michelson, P. F. Mizuno, T. Moiseev, A. A. Monzani, M. E. Morselli, A. Moskalenko, I. V. Murgia, S. Nakamori, T. Naumann-Godo, M. Nolan, P. L. Norris, J. P. Nuss, E. Ohsugi, T. Okumura, A. Omodei, N. Orlando, E. Paciesas, W. S. Pelassa, V. Pesce-Rollins, M. Pierbattista, M. Piron, F. Porter, T. A. Racusin, J. L. Raino, S. Razzano, M. Razzaque, S. Reimer, A. Reimer, O. Reyes, L. C. Roth, M. Sadrozinski, H. F. -W. Sgro, C. Siskind, E. J. Smith, P. D. Sonbas, E. Spandre, G. Spinelli, P. Stamatikos, M. Strickman, M. S. Takahashi, H. Tanaka, T. Tanaka, Y. Thayer, J. G. Thayer, J. B. Torres, D. F. Tosti, G. Troja, E. Uehara, T. Usher, T. L. Vandenbroucke, J. Vasileiou, V. Vianello, G. Vilchez, N. Vitale, V. von Kienlin, A. Waite, A. P. Wang, P. Winer, B. L. Wood, K. S. Yamazaki, R. Yang, Z. Ziegler, M. Piro, L. TI DETECTION OF HIGH-ENERGY GAMMA-RAY EMISSION DURING THE X-RAY FLARING ACTIVITY IN GRB 100728A SO ASTROPHYSICAL JOURNAL LETTERS LA English DT Article DE gamma-ray burst: individual (GRB100728A); radiation mechanisms: non-thermal ID AFTERGLOW LIGHT CURVES; FERMI OBSERVATIONS; BURST; SWIFT; TELESCOPE; MISSION; FLARES; COMPONENTS; EVOLUTION; ONSET AB We present the simultaneous Swift and Fermi observations of the bright GRB 100728A and its afterglow. The early X-ray emission is dominated by a vigorous flaring activity continuing until 1 ks after the burst. In the same time interval, high-energy emission is significantly detected by the Fermi/Large Area Telescope. Marginal evidence of GeV emission is observed up to later times. We discuss the broadband properties of this burst within both the internal and external shock scenarios, with a particular emphasis on the relation between X-ray flares, the GeV emission, and a continued long-duration central engine activity as their power source. C1 [Abdo, A. A.; Razzaque, S.] George Mason Univ, Ctr Earth Observing & Space Res, Coll Sci, Fairfax, VA 22030 USA. [Ackermann, M.; Ajello, M.; Bechtol, K.; Berenji, B.; Blandford, R. D.; Borgland, A. W.; Bouvier, A.; Buehler, R.; Cameron, R. A.; Charles, E.; Chiang, J.; Claus, R.; do Couto e Silva, E.; Drell, P. S.; Dubois, R.; Glanzman, T.; Godfrey, G.; Johnson, A. S.; Kamae, T.; Kerr, M.; Lande, J.; Lee, S. -H.; Michelson, P. F.; Monzani, M. E.; Moskalenko, I. V.; Murgia, S.; Nolan, P. L.; Omodei, N.; Orlando, E.; Porter, T. A.; Reimer, A.; Reimer, O.; Tanaka, T.; Thayer, J. G.; Thayer, J. B.; Usher, T. L.; Vandenbroucke, J.; Vianello, G.; Waite, A. P.; Wang, P.] Stanford Univ, WW Hansen Expt Phys Lab, Kavli Inst Particle Astrophys & Cosmol, Dept Phys, Stanford, CA 94305 USA. [Ackermann, M.; Ajello, M.; Bechtol, K.; Berenji, B.; Blandford, R. D.; Borgland, A. W.; Bouvier, A.; Buehler, R.; Cameron, R. A.; Charles, E.; Chekhtman, A.; Chiang, J.; Claus, R.; do Couto e Silva, E.; Drell, P. S.; Dubois, R.; Glanzman, T.; Godfrey, G.; Johnson, A. S.; Kamae, T.; Kerr, M.; Lande, J.; Lee, S. -H.; Michelson, P. F.; Monzani, M. E.; Moskalenko, I. V.; Murgia, S.; Nolan, P. L.; Omodei, N.; Orlando, E.; Porter, T. A.; Reimer, A.; Reimer, O.; Tanaka, T.; Thayer, J. G.; Thayer, J. B.; Usher, T. L.; Vandenbroucke, J.; Vianello, G.; Waite, A. P.; Wang, P.] Stanford Univ, SLAC Natl Accelerator Lab, Stanford, CA 94305 USA. [Baldini, L.; Bellazzini, R.; Bregeon, J.; Kuss, M.; Latronico, L.; Pesce-Rollins, M.; Razzano, M.; Sgro, C.; Spandre, G.] Ist Nazl Fis Nucl, Sez Pisa, I-56127 Pisa, Italy. [Ballet, J.; Casandjian, J. M.; Grenier, I. A.; Naumann-Godo, M.; Pierbattista, M.] Univ Paris Diderot, Lab AIM, CEA, IRFU,CNRS,Serv Astrophys,CEA Saclay, F-91191 Gif Sur Yvette, France. [Barbiellini, G.; Longo, F.] Ist Nazl Fis Nucl, Sez Trieste, I-34127 Trieste, Italy. [Barbiellini, G.; Longo, F.] Univ Trieste, Dipartimento Fis, I-34127 Trieste, Italy. [Baring, M. G.] Rice Univ, Dept Phys & Astron, Houston, TX 77251 USA. [Bastieri, D.; Buson, S.] Ist Nazl Fis Nucl, Sez Padova, I-35131 Padua, Italy. [Bastieri, D.; Buson, S.] Univ Padua, Dipartimento Fis G Galilei, I-35131 Padua, Italy. [Bhat, P. N.; Connaughton, V.; Guiriec, S.; Paciesas, W. S.] Univ Alabama, CSPAR, Huntsville, AL 35899 USA. [Bissaldi, E.; Reimer, A.; Reimer, O.] Leopold Franzens Univ Innsbruck, Inst Astro & Teilchenphys, A-6020 Innsbruck, Austria. [Bissaldi, E.; Reimer, A.; Reimer, O.] Leopold Franzens Univ Innsbruck, Inst Theoret Phys, A-6020 Innsbruck, Austria. [Bonamente, E.; Cecchi, C.; Germani, S.; Lubrano, P.; Tosti, G.] Ist Nazl Fis Nucl, Sez Perugia, I-06123 Perugia, Italy. [Bonamente, E.; Bouvier, A.; Cecchi, C.; Chekhtman, A.; Ciprini, S.; de Angelis, A.; Germani, S.; Lubrano, P.; Tosti, G.] Univ Perugia, Dipartimento Fis, I-06123 Perugia, Italy. [Bonnell, J.; Gehrels, N.; McEnery, J. E.; Moiseev, A. A.; Racusin, J. L.; Sonbas, E.; Stamatikos, M.; Troja, E.] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA. [Bonnell, J.; McEnery, J. E.; Moiseev, A. A.] Univ Maryland, Dept Phys, College Pk, MD 20742 USA. [Bonnell, J.; McEnery, J. E.; Moiseev, A. A.] Univ Maryland, Dept Astron, College Pk, MD 20742 USA. [Bouvier, A.; Sadrozinski, H. F. -W.; Ziegler, M.] Univ Calif Santa Cruz, Santa Cruz Inst Particle Phys, Dept Phys, Santa Cruz, CA 95064 USA. [Bouvier, A.; Sadrozinski, H. F. -W.; Ziegler, M.] Univ Calif Santa Cruz, Dept Astron & Astrophys, Santa Cruz, CA 95064 USA. [Brigida, M.; de Palma, F.; Favuzzi, C.; Fusco, P.; Giglietto, N.; Giordano, F.; Loparco, F.; Raino, S.; Spinelli, P.] Univ Politecn Bari, Dipartimento Fis M Merlin, I-70126 Bari, Italy. [Bouvier, A.; Brigida, M.; de Palma, F.; Favuzzi, C.; Fusco, P.; Gargano, F.; Giglietto, N.; Giordano, F.; Loparco, F.; Mazziotta, M. N.; Raino, S.; Spinelli, P.] Ist Nazl Fis Nucl, Sez Bari, I-70126 Bari, Italy. [Bruel, P.] Ecole Polytech, CNRS, IN2P3, Lab Leprince Ringuet, F-91128 Palaiseau, France. [Caliandro, G. A.; Hadasch, D.; Torres, D. F.] CSIC, IEEC, Inst Ciencies Espai, Barcelona 08193, Spain. [Caraveo, P. A.] INAF Ist Astrofis Spaziale & Fis Cosm, I-20133 Milan, Italy. [Chekhtman, A.] Artep Inc, Ellicott City, MD 21042 USA. [Conrad, J.; Yang, Z.] Stockholm Univ, Dept Phys, SE-10691 Stockholm, Sweden. [Conrad, J.; Yang, Z.] Oskar Klein Ctr Cosmoparticle Phys, SE-10691 Stockholm, Sweden. [Cutini, S.; Giommi, P.] Agenzia Spaziale Italiana, Sci Data Ctr, I-00044 Rome, Italy. [de Angelis, A.] Univ Udine, Dipartimento Fis, I-33100 Udine, Italy. [de Angelis, A.] Ist Nazl Fis Nucl, Sez Trieste, Grp Collegato Udine, I-33100 Udine, Italy. [Dermer, C. D.; Strickman, M. S.; Wood, K. S.] USN, Div Space Sci, Res Lab, Washington, DC 20375 USA. [Fukazawa, Y.; Hanabata, Y.; Katagiri, H.; Mizuno, T.; Uehara, T.] Hiroshima Univ, Dept Phys Sci, Hiroshima 7398526, Japan. [Giroletti, M.] INAF Ist Radioastron, I-40129 Bologna, Italy. [Granot, J.] Univ Hertfordshire, Sci & Technol Res Inst, Ctr Astrophys Res, Hatfield AL10 9AB, Herts, England. [Hughes, R. E.; Smith, P. D.; Stamatikos, M.; Winer, B. L.] Ohio State Univ, Dept Phys, Ctr Cosmol & Astroparticle Phys, Columbus, OH 43210 USA. [Johannesson, G.] Univ Iceland, Inst Sci, IS-107 Reykjavik, Iceland. [Kataoka, J.; Nakamori, T.] Waseda Univ, Res Inst Sci & Engn, Shinjuku Ku, Tokyo 1698555, Japan. [Knoedlseder, J.; Vilchez, N.] IRAP, CNRS, F-31028 Toulouse 4, France. [Knoedlseder, J.; Vilchez, N.] Univ Toulouse, UPS OMP, IRAP, Toulouse, France. [Lott, B.] Univ Bordeaux 1, CNRS, IN2P3, Ctr Etud Nucl Bordeaux Gradignan, F-33175 Gradignan, France. [Meszaros, P.] Penn State Univ, Dept Astron & Astrophys, University Pk, PA 16802 USA. [Moiseev, A. A.] CRESST, Greenbelt, MD 20771 USA. [Morselli, A.; Vitale, V.] Ist Nazl Fis Nucl, Sez Roma Tor Vergata, I-00133 Rome, Italy. [Norris, J. P.] Univ Denver, Dept Phys & Astron, Denver, CO 80208 USA. [Nuss, E.; Pelassa, V.; Piron, F.; Vasileiou, V.] Univ Montpellier 2, Lab Universe & Particules Montpellier, CNRS, IN2P3, Montpellier, France. [Ohsugi, T.; Takahashi, H.] Hiroshima Univ, Hiroshima Astrophys Sci Ctr, Hiroshima 7398526, Japan. [Okumura, A.; Tanaka, Y.] JAXA, Inst Space & Astronaut Sci, Chuo Ku, Kanagawa 2525210, Japan. [Orlando, E.; von Kienlin, A.] Max Planck Inst Extraterr Phys, D-85748 Garching, Germany. [Reyes, L. C.] Univ Chicago, Kavli Inst Cosmol Phys, Chicago, IL 60637 USA. [Roth, M.] Univ Washington, Dept Phys, Seattle, WA 98195 USA. [Siskind, E. J.] NYCB Real Time Comp Inc, Lattingtown, NY 11560 USA. [Sonbas, E.] Adiyaman Univ, Dept Phys, TR-02040 Adiyaman, Turkey. [Sonbas, E.] USRA, Columbia, MD 21044 USA. [Torres, D. F.] ICREA, Barcelona, Spain. [Vianello, G.] CIFS, I-10133 Turin, Italy. [Vitale, V.] Univ Roma Tor Vergata, Dipartimento Fis, I-00133 Rome, Italy. [Yamazaki, R.] Aoyama Gakuin Univ, Dept Math & Phys, Kanagawa 2525258, Japan. [Piro, L.] INAF Ist Astrofis Spaziale & Fis Cosm, I-00133 Rome, Italy. RP Abdo, AA (reprint author), George Mason Univ, Ctr Earth Observing & Space Res, Coll Sci, Fairfax, VA 22030 USA. EM sarac@slac.stanford.edu; Julie.E.McEnery@nasa.gov; eleonora.troja@nasa.gov; vlasios.vasileiou@univ-montp2.fr; luigi.piro@iasf-roma.inaf.it RI Gargano, Fabio/O-8934-2015; Moskalenko, Igor/A-1301-2007; Mazziotta, Mario /O-8867-2015; Sgro, Carmelo/K-3395-2016; Bissaldi, Elisabetta/K-7911-2016; Torres, Diego/O-9422-2016; Orlando, E/R-5594-2016; Kuss, Michael/H-8959-2012; giglietto, nicola/I-8951-2012; Reimer, Olaf/A-3117-2013; Tosti, Gino/E-9976-2013; PIRO, LUIGI/E-4954-2013; Johannesson, Gudlaugur/O-8741-2015; Loparco, Francesco/O-8847-2015; Morselli, Aldo/G-6769-2011; Racusin, Judith/D-2935-2012; Gehrels, Neil/D-2971-2012; McEnery, Julie/D-6612-2012; Baldini, Luca/E-5396-2012; lubrano, pasquale/F-7269-2012 OI Giroletti, Marcello/0000-0002-8657-8852; Cutini, Sara/0000-0002-1271-2924; Baldini, Luca/0000-0002-9785-7726; Gargano, Fabio/0000-0002-5055-6395; Moskalenko, Igor/0000-0001-6141-458X; Mazziotta, Mario /0000-0001-9325-4672; Bissaldi, Elisabetta/0000-0001-9935-8106; Torres, Diego/0000-0002-1522-9065; giommi, paolo/0000-0002-2265-5003; De Angelis, Alessandro/0000-0002-3288-2517; Caraveo, Patrizia/0000-0003-2478-8018; Sgro', Carmelo/0000-0001-5676-6214; Bastieri, Denis/0000-0002-6954-8862; Omodei, Nicola/0000-0002-5448-7577; Pesce-Rollins, Melissa/0000-0003-1790-8018; giglietto, nicola/0000-0002-9021-2888; Reimer, Olaf/0000-0001-6953-1385; PIRO, LUIGI/0000-0003-4159-3984; Johannesson, Gudlaugur/0000-0003-1458-7036; Loparco, Francesco/0000-0002-1173-5673; Morselli, Aldo/0000-0002-7704-9553; lubrano, pasquale/0000-0003-0221-4806 FU K. A. Wallenberg Foundation; NASA FX Royal Swedish Academy of Sciences Research Fellow, funded by a grant from the K. A. Wallenberg Foundation.; E.T. was supported by an appointment to the NASA Postdoctoral Program at the Goddard Space Flight Center, administered by Oak Ridge Associated Universities through a contract with NASA. NR 37 TC 25 Z9 25 U1 0 U2 8 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 2041-8205 J9 ASTROPHYS J LETT JI Astrophys. J. Lett. PD JUN 20 PY 2011 VL 734 IS 2 AR L27 DI 10.1088/2041-8205/734/2/L27 PG 6 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 797NX UT WOS:000293135700002 ER PT J AU Draa, MN Hastings, AS Williams, KJ AF Draa, Meredith N. Hastings, Alexander S. Williams, Keith J. TI Comparison of photodiode nonlinearity measurement systems SO OPTICS EXPRESS LA English DT Article ID DISTORTION; PHOTODETECTORS AB Photodiode nonlinearity measurements using one-, two- and three-tone measurement systems are compared with each other, to investigate the comparison accuracy between setups. The mathematical relationship between each setup is analyzed, and data on multiple devices are compared to find under which conditions the measurements are comparable. It is shown that the three measurement systems can be used interchangeably only when the distortion adheres to the expected mathematical slopes. (C)2011 Optical Society of America C1 [Draa, Meredith N.] Global Def Technol & Syst Inc, Crofton, MD 21114 USA. [Hastings, Alexander S.; Williams, Keith J.] USN, Res Lab, Photon Technol Branch, Washington, DC 20032 USA. RP Draa, MN (reprint author), Global Def Technol & Syst Inc, 2200 Def Highway,Suite 405, Crofton, MD 21114 USA. EM meredith.draa.ctr@nrl.navy.mil NR 13 TC 16 Z9 16 U1 0 U2 5 PU OPTICAL SOC AMER PI WASHINGTON PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA SN 1094-4087 J9 OPT EXPRESS JI Opt. Express PD JUN 20 PY 2011 VL 19 IS 13 BP 12635 EP 12645 DI 10.1364/OE.19.012635 PG 11 WC Optics SC Optics GA 794AY UT WOS:000292867600080 PM 21716505 ER PT J AU Thernisien, A Vourlidas, A Howard, RA AF Thernisien, A. Vourlidas, A. Howard, R. A. TI CME reconstruction: Pre-STEREO and STEREO era SO JOURNAL OF ATMOSPHERIC AND SOLAR-TERRESTRIAL PHYSICS LA English DT Article DE Solar corona; Coronal mass ejections; 3D reconstruction; Modeling ID CORONAL MASS EJECTIONS; INTERPLANETARY SCINTILLATION OBSERVATIONS; 3-DIMENSIONAL STRUCTURE; CONE MODEL; SOLAR CORONA; MAGNETIC CLOUDS; TRANSIENTS; LASCO; LOOP; TOMOGRAPHY AB Since the first observations of coronal mass ejections (CMEs) in 1970s, their three-dimensional (3D) morphology has been a key ingredient for understanding their origin and evolution. The determination of their 3D structure using a single viewpoint, however posed a challenge because only their 2D projection on the sky plane is observed. The operation of the STEREO mission with its unique capability of imaging the inner heliosphere from two viewpoints has greatly improved this situation. It is therefore timely to review the pre-STEREO efforts in 3D CME reconstruction and compare them with the first STEREO results in this area. Our paper focuses on the techniques relevant to the CME morphology: forward modeling, polarimetric, spectroscopic, direct inversion. We also discuss the limitations and considerations involved in each technique. (C) 2010 Elsevier Ltd. All rights reserved. C1 [Thernisien, A.] ARTEP Inc, Ellicott City, MD 21042 USA. [Vourlidas, A.; Howard, R. A.] NRL, Washington, DC 20375 USA. RP Thernisien, A (reprint author), ARTEP Inc, 2922 Excelsior Springs Court, Ellicott City, MD 21042 USA. EM arnaud.thernisien@nrl.navy.mil; angelos.vourlidas@nrl.navy.mil; russ.howard@nrl.navy.mil RI Vourlidas, Angelos/C-8231-2009 OI Vourlidas, Angelos/0000-0002-8164-5948 FU NASA FX We thank the referees for their helpful comments. The SECCHI data used here were produced by an international consortium of the Naval Research Laboratory (USA), Lockheed Martin Solar and Astrophysics Lab (USA), NASA Goddard Space Flight Center (USA), Rutherford Appleton Laboratory (UK), University of Birmingham (UK), Max-Planck Institute for Solar System Research (Germany), Centre Spatiale de Liege (Belgium), Institut d'Optique Theorique et Appliquee (France), and Institut d'Astrophysique Spatiale (France). This work was supported by NASA. NR 87 TC 16 Z9 16 U1 0 U2 5 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 1364-6826 J9 J ATMOS SOL-TERR PHY JI J. Atmos. Sol.-Terr. Phys. PD JUN 20 PY 2011 VL 73 IS 10 SI SI BP 1156 EP 1165 DI 10.1016/j.jastp.2010.10.019 PG 10 WC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences SC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences GA 788XJ UT WOS:000292477400008 ER PT J AU Liewer, PC Hall, JR Howard, RA De Jong, EM Thompson, WT Thernisien, A AF Liewer, P. C. Hall, J. R. Howard, R. A. De Jong, E. M. Thompson, W. T. Thernisien, A. TI Stereoscopic analysis of STEREO/SECCHI data for CME trajectory determination SO JOURNAL OF ATMOSPHERIC AND SOLAR-TERRESTRIAL PHYSICS LA English DT Article DE Coronal mass ejections; Stereoscopy; STEREO ID CORONAL MASS EJECTIONS; SOLAR; RECONSTRUCTION; IMAGES; SECCHI; SUN AB The Sun Earth Connection Coronal and Heliospheric Investigation (SECCHI) coronagraphs on the twin Solar TErrestrial RElations Observatory (STEREO) spacecraft provide simultaneous views of the corona and coronal mass ejections from two view points. Here, we analyze simultaneous image pairs using the technique of tie-pointing and triangulation (T&T) to determine the three-dimensional trajectory of seven coronal mass ejections (CMEs). The bright leading edge of a CME seen in coronagraph images results from line-of-sight integration through the CME front; the two STEREO coronagraphs see different apparent leading edges, leading to a systematic error in its three-dimensional reconstruction. We analyze this systematic error using a simple geometric model of a CME front. We validate the technique and analysis by comparing T&T trajectory determinations for seven CMEs with trajectories determined by Thernisien et al. (2009) using a forward modeling technique not susceptible to this systematic effect. We find that, for the range of spacecraft separation studied ( <= 50), T&T gives reliable trajectories (uncertainty < 10 degrees in direction and < 15% velocity) for CME propagating within approximately +/- 40 degrees of perpendicular to Sun-Earth line. For CMEs close to the Sun-Earth or Sun-Spacecraft lines, T&T is subject to larger errors, especially in the velocity. (C) 2010 Elsevier Ltd. All rights reserved. C1 [Liewer, P. C.; Hall, J. R.; De Jong, E. M.] CALTECH, Jet Prop Lab, Pasadena, CA 91109 USA. [Howard, R. A.] USN, Res Lab, Washington, DC 20375 USA. [Thompson, W. T.] Adnet Syst Inc, Lanham, MD 20706 USA. [Thernisien, A.] Univ Space Res Assoc, Columbia, MD 21044 USA. RP Liewer, PC (reprint author), CALTECH, Jet Prop Lab, MS 169-506, Pasadena, CA 91109 USA. EM paulett.liewer@jpl.nasa.gov RI Thompson, William/D-7376-2012 FU NASA; UK institutions by Particle Physics and Astronomy Research Council (PPARC); German institutions by Deutsches Zentrum fur Luft- und Raumfahrt e.V. (DLR); Belgian institutions by Belgian Science Policy Office; French institutions by Center National d'Etudes Spatiales (CNES); Center National de la Recherche Scientifique (CNRS); USAF; Office of Naval Research FX We thank A. Vourlidas and S. Plunkett for useful discussions. We thank N. Rich and S. Suzuki for their help with the SECCHI data. The STEREO/SECCHI data used here are produced by an international consortium of the Naval Research Laboratory (USA), Lockheed-Martin Solar and Astrophysics Lab (USA), NASA Goddard Space Flight Center (USA), Rutherford Appleton Laboratory (UK), University of Birmingham (UK), Max-Planck-Institut fur Sonnensystemforschung (Germany), Center Spatiale de Liege (Belgium), Institut d'Optique Theorique et Appliquee (France), Institut d'Astrophysique Spatiale (France). The USA institutions were funded by NASA; the UK institutions by Particle Physics and Astronomy Research Council (PPARC); the German institutions by Deutsches Zentrum fur Luft- und Raumfahrt e.V. (DLR); the Belgian institutions by Belgian Science Policy Office; the French institutions by Center National d'Etudes Spatiales (CNES) and the Center National de la Recherche Scientifique (CNRS). The NRL effort was also supported by the USAF Space Test Program and the Office of Naval Research. A portion of this work was carried out at the Jet Propulsion Laboratory, California Institute of Technology under a contract with NASA. NR 28 TC 7 Z9 8 U1 0 U2 5 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 1364-6826 J9 J ATMOS SOL-TERR PHY JI J. Atmos. Sol.-Terr. Phys. PD JUN 20 PY 2011 VL 73 IS 10 SI SI BP 1173 EP 1186 DI 10.1016/j.jastp.2010.09.004 PG 14 WC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences SC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences GA 788XJ UT WOS:000292477400010 ER PT J AU Rouillard, AP AF Rouillard, A. P. TI Relating white light and in situ observations of coronal mass ejections: A review SO JOURNAL OF ATMOSPHERIC AND SOLAR-TERRESTRIAL PHYSICS LA English DT Review DE Solar wind; White light images; Coronal mass ejections; Magnetohydrodynamics ID MAGNETIC CLOUD EXPANSION; INTER-PLANETARY SHOCK; SOLAR-CYCLE VARIATION; FLUX ROPE; 1 AU; HELIOSPHERIC IMAGERS; INTERACTION REGIONS; STREAMER BLOBS; WIND; FIELD AB This paper provides a short review of some of the basic concepts related to the observations of coronal mass ejections (CMEs) in white light images and at large distances from the Sun. We review the various ideas which have been put forward to explain the dramatic changes in CME appearance in white light images from the Sun to 1 AU, focusing on results obtained by comparing white light observations of CMEs to the in situ measurements of Interplanetary CMEs (or ICMEs). We start with a list of definitions for the various in situ structures that form an ICME. A few representative examples of the formation of sheath regions and other interaction regions as well as the expansion of magnetic flux ropes are used to illustrate the basic phenomena which induce significant brightness variations during a CME's propagation to 1 AU and beyond. The white light signatures of a number of CMEs observed by the coronagraphs have been successfully simulated numerically by assuming that most of the coronal plasma observed in white light images is located on the surface of a croissant-shaped structure reminiscent of a magnetic flux rope. At large distances from the Sun, white light imagers show that the appearance of CMEs changes dramatically due to the changing position of the CME relative to the Thomson sphere, the expansion of the ejecta and the interaction of the ejecta with the ambient solar wind. (C) 2010 Elsevier Ltd. All rights reserved. C1 [Rouillard, A. P.] George Mason Univ, Coll Sci, Fairfax, VA 22030 USA. [Rouillard, A. P.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. RP Rouillard, AP (reprint author), George Mason Univ, Coll Sci, Fairfax, VA 22030 USA. EM arouilla@gmu.edu FU NASA FX The author wishes to thank Jackie Davies, Neil Sheeley, Benoit Lavraud, Yi-Ming Wang and Mike Lockwood for their continuous scientific and technical support as well as all the scientist and engineers which have contributed to the STEREO mission. The author also thanks the two referees for their detailed and very constructive reports which have greatly improved this review. The STEREO/SECCHI data are produced by a consortium of RAL (UK), NRL (USA), LMSAL (USA), GSFC (USA), MPS (Germany), CSL (Belgium). IOTA (France) and IAS (France). The ACE data were obtained from the ACE science center. This work was supported by NASA. NR 100 TC 30 Z9 30 U1 0 U2 2 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 1364-6826 EI 1879-1824 J9 J ATMOS SOL-TERR PHY JI J. Atmos. Sol.-Terr. Phys. PD JUN 20 PY 2011 VL 73 IS 10 SI SI BP 1201 EP 1213 DI 10.1016/j.jastp.2010.08.015 PG 13 WC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences SC Geochemistry & Geophysics; Meteorology & Atmospheric Sciences GA 788XJ UT WOS:000292477400012 ER PT J AU Dodoo, D Hollingdale, MR Anum, D Koram, KA Gyan, B Akanmori, BD Ocran, J Adu-Amankwah, S Geneshan, H Abot, E Legano, J Banania, G Sayo, R Brambilla, D Kumar, S Doolan, DL Rogers, WO Epstein, J Richie, TL Sedegah, M AF Dodoo, Daniel Hollingdale, Michael R. Anum, Dorothy Koram, Kwadwo A. Gyan, Ben Akanmori, Bartholomew D. Ocran, Josephine Adu-Amankwah, Susan Geneshan, Harini Abot, Esteban Legano, Jennylyn Banania, Glenna Sayo, Renato Brambilla, Donald Kumar, Sanjai Doolan, Denise L. Rogers, William O. Epstein, Judith Richie, Thomas L. Sedegah, Martha TI Measuring naturally acquired immune responses to candidate malaria vaccine antigens in Ghanaian adults SO MALARIA JOURNAL LA English DT Article ID MEROZOITE SURFACE PROTEIN-1; T-CELL EPITOPES; FALCIPARUM CIRCUMSPOROZOITE PROTEIN; HEPATOCYTE ERYTHROCYTE PROTEIN; BLOOD-STAGE ANTIGEN; PLASMODIUM-FALCIPARUM; CLINICAL MALARIA; ANTIBODY-RESPONSES; ADHESIVE PROTEIN; INTERFERON-GAMMA AB Background: To prepare field sites for malaria vaccine trials, it is important to determine baseline antibody and T cell responses to candidate malaria vaccine antigens. Assessing T cell responses is especially challenging, given genetic restriction, low responses observed in endemic areas, their variability over time, potential suppression by parasitaemia and the intrinsic variability of the assays. Methods: In Part A of this study, antibody titres were measured in adults from urban and rural communities in Ghana to recombinant Plasmodium falciparum CSP, SSP2/TRAP, LSA1, EXP1, MSP1, MSP3 and EBA175 by ELISA, and to sporozoites and infected erythrocytes by IFA. Positive ELISA responses were determined using two methods. T cell responses to defined CD8 or CD4 T cell epitopes from CSP, SSP2/TRAP, LSA1 and EXP1 were measured by ex vivo IFN-g ELISpot assays using HLA-matched Class I-and DR-restricted synthetic peptides. In Part B, the reproducibility of the ELISpot assay to CSP and AMA1 was measured by repeating assays of individual samples using peptide pools and low, medium or high stringency criteria for defining positive responses, and by comparing samples collected two weeks apart. Results: In Part A, positive antibody responses varied widely from 17%-100%, according to the antigen and statistical method, with blood stage antigens showing more frequent and higher magnitude responses. ELISA titres were higher in rural subjects, while IFA titres and the frequencies and magnitudes of ex vivo ELISpot activities were similar in both communities. DR-restricted peptides showed stronger responses than Class I-restricted peptides. In Part B, the most stringent statistical criteria gave the fewest, and the least stringent the most positive responses, with reproducibility slightly higher using the least stringent method when assays were repeated. Results varied significantly between the two-week time-points for many participants. Conclusions: All participants were positive for at least one malaria protein by ELISA, with results dependent on the criteria for positivity. Likewise, ELISpot responses varied among participants, but were relatively reproducible by the three methods tested, especially the least stringent, when assays were repeated. However, results often differed between samples taken two weeks apart, indicating significant biological variability over short intervals. C1 [Hollingdale, Michael R.; Geneshan, Harini; Abot, Esteban; Legano, Jennylyn; Banania, Glenna; Sayo, Renato; Epstein, Judith; Richie, Thomas L.; Sedegah, Martha] USN, US Mil Malaria Vaccine Program, Med Res Ctr, Silver Spring, MD 20910 USA. [Dodoo, Daniel; Anum, Dorothy; Koram, Kwadwo A.; Gyan, Ben; Akanmori, Bartholomew D.; Ocran, Josephine; Adu-Amankwah, Susan; Rogers, William O.] Univ Ghana, Noguchi Mem Inst Med Res, Legon, Ghana. [Akanmori, Bartholomew D.] WHO Reg Off Africa, Brazzaville, Congo. [Brambilla, Donald] RTI Rockville, Rockville, MD 20852 USA. [Kumar, Sanjai] US FDA, Ctr Biol Review & Res, Rockville, MD 20892 USA. [Rogers, William O.] Naval Med Res Unit 3, Cairo, Egypt. [Doolan, Denise L.] Queensland Inst Med Res, Brisbane, Qld 4006, Australia. RP Sedegah, M (reprint author), USN, US Mil Malaria Vaccine Program, Med Res Ctr, Silver Spring, MD 20910 USA. EM martha.sedegah@med.navy.mil RI Doolan, Denise/F-1969-2015; OI Richie, Thomas/0000-0002-2946-5456 FU U.S. Naval Medical Research Center [6000.RAD1.F.A0309]; National Institutes of Allergy and Infectious Diseases, National Institutes of Health [NO1 AI95363] FX The studies were supported by U.S. Naval Medical Research Center work unit number 6000.RAD1.F.A0309 and National Institutes of Allergy and Infectious Diseases, National Institutes of Health contract NO1 AI95363. We thank David Lanar and David Narum for the gift of recombinant P. falciparum proteins and John Arko-Mensah and Eric Kyei-Baafour for technical assistance. The study was approved by the Institutional Review Boards of the Noguchi Memorial Institute for Medical Research and the U.S. Naval Medical Research Center and conducted in accordance with the International Conference on Harmonisation (ICH), current Good Clinical Practices (cGCP), and U.S. Navy regulations (SECNAVINST 3900.39B) governing the use of human subjects in medical research. The views expressed herein are the personal ones of the authors and do not purport to reflect the views of the U.S. Navy, the Department of Defense, or the Food and Drug Administration. NR 66 TC 21 Z9 21 U1 0 U2 2 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1475-2875 J9 MALARIA J JI Malar. J. PD JUN 20 PY 2011 VL 10 AR 168 DI 10.1186/1475-2875-10-168 PG 18 WC Infectious Diseases; Parasitology; Tropical Medicine SC Infectious Diseases; Parasitology; Tropical Medicine GA 789LQ UT WOS:000292517400001 PM 21689436 ER PT J AU Abdo, AA Ackermann, M Ajello, M Baldini, L Ballet, J Barbiellini, G Bastieri, D Bechtol, K Bellazzini, R Berenji, B Bonamente, E Borgland, AW Bouvier, A Bregeon, J Brez, A Brigida, M Bruel, P Buehler, R Buson, S Caliandro, GA Cameron, RA Caraveo, PA Casandjian, JM Cecchi, C Charles, E Chekhtman, A Chiang, J Ciprini, S Claus, R Cohen-Tanugi, J Conrad, J Cutini, S de Angelis, A de Palma, F Dermer, CD Digel, SW Silva, EDE Drell, PS Dubois, R Favuzzi, C Fegan, SJ Focke, WB Fortin, P Frailis, M Funk, S Fusco, P Gargano, F Gasparrini, D Gehrels, N Germani, S Giglietto, N Giordano, F Giroletti, M Glanzman, T Godfrey, G Grenier, IA Grillo, L Guiriec, S Hadasch, D Hays, E Hughes, RE Iafrate, G Johannesson, G Johnson, AS Johnson, TJ Kamae, T Katagiri, H Kataoka, J Knodlseder, J Kuss, M Lande, J Latronico, L Lee, SH Lionetto, AM Longo, F Loparco, F Lott, B Lovellette, MN Lubrano, P Makeev, A Mazziotta, MN McEnery, JE Mehault, J Michelson, PF Mitthumsiri, W Mizuno, T Moiseev, AA Monte, C Monzani, ME Morselli, A Moskalenko, IV Murgia, S Nakamori, T Naumann-Godo, M Nolan, PL Norris, JP Nuss, E Ohsugi, T Okumura, A Omodei, N Orlando, E Ormes, JF Ozaki, M Paneque, D Pelassa, V Pesce-Rollins, M Pierbattista, M Piron, F Porter, TA Raino, S Rando, R Razzano, M Reimer, A Reimer, O Reposeur, T Ritz, S Sadrozinski, HFW Schalk, TL Sgro, C Share, GH Siskind, EJ Smith, PD Spandre, G Spinelli, P Strickman, MS Strong, AW Takahashi, H Tanaka, T Thayer, JG Thayer, JB Thompson, DJ Tibaldo, L Torres, DF Tosti, G Tramacere, A Troja, E Uchiyama, Y Usher, TL Vandenbroucke, J Vasileiou, V Vianello, G Vilchez, N Vitale, V Vladimirov, AE Waite, AP Wang, P Winer, BL Wood, KS Yang, Z Ziegler, M AF Abdo, A. A. Ackermann, M. Ajello, M. Baldini, L. Ballet, J. Barbiellini, G. Bastieri, D. Bechtol, K. Bellazzini, R. Berenji, B. Bonamente, E. Borgland, A. W. Bouvier, A. Bregeon, J. Brez, A. Brigida, M. Bruel, P. Buehler, R. Buson, S. Caliandro, G. A. Cameron, R. A. Caraveo, P. A. Casandjian, J. M. Cecchi, C. Charles, E. Chekhtman, A. Chiang, J. Ciprini, S. Claus, R. Cohen-Tanugi, J. Conrad, J. Cutini, S. de Angelis, A. de Palma, F. Dermer, C. D. Digel, S. W. do Couto e Silva, E. Drell, P. S. Dubois, R. Favuzzi, C. Fegan, S. J. Focke, W. B. Fortin, P. Frailis, M. Funk, S. Fusco, P. Gargano, F. Gasparrini, D. Gehrels, N. Germani, S. Giglietto, N. Giordano, F. Giroletti, M. Glanzman, T. Godfrey, G. Grenier, I. A. Grillo, L. Guiriec, S. Hadasch, D. Hays, E. Hughes, R. E. Iafrate, G. Johannesson, G. Johnson, A. S. Johnson, T. J. Kamae, T. Katagiri, H. Kataoka, J. Knoedlseder, J. Kuss, M. Lande, J. Latronico, L. Lee, S. -H. Lionetto, A. M. Longo, F. Loparco, F. Lott, B. Lovellette, M. N. Lubrano, P. Makeev, A. Mazziotta, M. N. McEnery, J. E. Mehault, J. Michelson, P. F. Mitthumsiri, W. Mizuno, T. Moiseev, A. A. Monte, C. Monzani, M. E. Morselli, A. Moskalenko, I. V. Murgia, S. Nakamori, T. Naumann-Godo, M. Nolan, P. L. Norris, J. P. Nuss, E. Ohsugi, T. Okumura, A. Omodei, N. Orlando, E. Ormes, J. F. Ozaki, M. Paneque, D. Pelassa, V. Pesce-Rollins, M. Pierbattista, M. Piron, F. Porter, T. A. Raino, S. Rando, R. Razzano, M. Reimer, A. Reimer, O. Reposeur, T. Ritz, S. Sadrozinski, H. F. -W. Schalk, T. L. Sgro, C. Share, G. H. Siskind, E. J. Smith, P. D. Spandre, G. Spinelli, P. Strickman, M. S. Strong, A. W. Takahashi, H. Tanaka, T. Thayer, J. G. Thayer, J. B. Thompson, D. J. Tibaldo, L. Torres, D. F. Tosti, G. Tramacere, A. Troja, E. Uchiyama, Y. Usher, T. L. Vandenbroucke, J. Vasileiou, V. Vianello, G. Vilchez, N. Vitale, V. Vladimirov, A. E. Waite, A. P. Wang, P. Winer, B. L. Wood, K. S. Yang, Z. Ziegler, M. TI FERMI LARGE AREA TELESCOPE OBSERVATIONS OF TWO GAMMA-RAY EMISSION COMPONENTS FROM THE QUIESCENT SUN SO ASTROPHYSICAL JOURNAL LA English DT Article DE astroparticle physics; cosmic rays; gamma rays: general; Sun: atmosphere; Sun: heliosphere; Sun: X-rays, gamma rays ID GALACTIC COSMIC-RAYS; INVERSE COMPTON-SCATTERING; HELIOSPHERIC MODULATION; EGRET DATA; SOLAR; PROPAGATION; SPECTRUM; GALAXY; PARTICLES; ASTRONOMY AB We report the detection of high-energy gamma-rays from the quiescent Sun with the Large Area Telescope on board the Fermi Gamma-Ray Space Telescope (Fermi) during the first 18 months of the mission. These observations correspond to the recent period of low solar activity when the emission induced by cosmic rays (CRs) is brightest. For the first time, the high statistical significance of the observations allows clear separation of the two components: the point-like emission from the solar disk due to CR cascades in the solar atmosphere and extended emission from the inverse Compton (IC) scattering of CR electrons on solar photons in the heliosphere. The observed integral flux (>= 100 MeV) from the solar disk is (4.6 +/- 0.2inverted right perpendicularstatistical errorinverted left perpendicular(-0.08)(+1.0)inverted right perpendicularsystematic errorinverted left perpendicular) x 10(-7) cm(-2) s(-1), which is similar to 7 times higher than predicted by the "nominal" model of Seckel et al. In contrast, the observed integral flux (>= 100 MeV) of the extended emission from a region of 20 degrees radius centered on the Sun, but excluding the disk itself, (6.8 +/- 0.7[stat.](-0.4)(+0.5)[syst.]) x 10(-7) cm(-2) s(-1), along with the observed spectrum and the angular profile, is in good agreement with the theoretical predictions for the IC emission. C1 [Abdo, A. A.; Makeev, A.] George Mason Univ, Ctr Earth Observing & Space Res, Coll Sci, Fairfax, VA 22030 USA. [Ackermann, M.; Ajello, M.; Bechtol, K.; Berenji, B.; Borgland, A. W.; Buehler, R.; Cameron, R. A.; Charles, E.; Chiang, J.; Claus, R.; Digel, S. W.; do Couto e Silva, E.; Drell, P. S.; Dubois, R.; Focke, W. B.; Funk, S.; Glanzman, T.; Godfrey, G.; Grillo, L.; Johnson, A. S.; Kamae, T.; Lande, J.; Lee, S. -H.; Michelson, P. F.; Mitthumsiri, W.; Monzani, M. E.; Moskalenko, I. V.; Murgia, S.; Nolan, P. L.; Omodei, N.; Orlando, E.; Paneque, D.; Porter, T. A.; Reimer, A.; Reimer, O.; Tanaka, T.; Thayer, J. G.; Thayer, J. B.; Tramacere, A.; Uchiyama, Y.; Usher, T. L.; Vandenbroucke, J.; Vianello, G.; Vladimirov, A. E.; Waite, A. P.; Wang, P.] Stanford Univ, Kavli Inst Particle Astrophys & Cosmol, Dept Phys, Stanford, CA 94305 USA. [Ackermann, M.; Ajello, M.; Bechtol, K.; Berenji, B.; Borgland, A. W.; Buehler, R.; Cameron, R. A.; Charles, E.; Chiang, J.; Claus, R.; Digel, S. W.; do Couto e Silva, E.; Drell, P. S.; Dubois, R.; Focke, W. B.; Funk, S.; Glanzman, T.; Godfrey, G.; Grillo, L.; Johnson, A. S.; Kamae, T.; Lande, J.; Lee, S. -H.; Michelson, P. F.; Mitthumsiri, W.; Monzani, M. E.; Moskalenko, I. V.; Murgia, S.; Nolan, P. L.; Omodei, N.; Orlando, E.; Paneque, D.; Porter, T. A.; Reimer, A.; Reimer, O.; Tanaka, T.; Thayer, J. G.; Thayer, J. B.; Tramacere, A.; Uchiyama, Y.; Usher, T. L.; Vandenbroucke, J.; Vianello, G.; Vladimirov, A. E.; Waite, A. P.; Wang, P.] Stanford Univ, Kavli Inst Particle Astrophys & Cosmol, SLAC Natl Accelerator Lab, WW Hansen Expt Phys Lab, Stanford, CA 94305 USA. [Baldini, L.; Bellazzini, R.; Bregeon, J.; Brez, A.; Kuss, M.; Latronico, L.; Pesce-Rollins, M.; Razzano, M.; Sgro, C.; Spandre, G.] Ist Nazl Fis Nucl, Sez Pisa, I-56127 Pisa, Italy. [Ballet, J.; Casandjian, J. M.; Grenier, I. A.; Naumann-Godo, M.; Pierbattista, M.; Tibaldo, L.] Univ Paris Diderot, Lab AIM, CEA IRFU, CNRS,Serv Astrophys,CEA Saclay, F-91191 Gif Sur Yvette, France. [Barbiellini, G.; Iafrate, G.; Longo, F.] Ist Nazl Fis Nucl, Sez Trieste, I-34127 Trieste, Italy. [Barbiellini, G.; Longo, F.] Univ Trieste, Dipartimento Fis, I-34127 Trieste, Italy. [Bastieri, D.; Buson, S.; Rando, R.; Tibaldo, L.] Ist Nazl Fis Nucl, Sez Padova, I-35131 Padua, Italy. [Bastieri, D.; Buson, S.; Rando, R.; Tibaldo, L.] Univ Padua, Dipartimento Fis G Galilei, I-35131 Padua, Italy. [Bonamente, E.; Cecchi, C.; Germani, S.; Lubrano, P.; Tosti, G.] Ist Nazl Fis Nucl, Sez Perugia, I-06123 Perugia, Italy. [Bonamente, E.; Cecchi, C.; Ciprini, S.; Germani, S.; Lubrano, P.; Tosti, G.] Univ Perugia, Dipartimento Fis, I-06123 Perugia, Italy. [Bouvier, A.; Ritz, S.; Sadrozinski, H. F. -W.; Schalk, T. L.; Ziegler, M.] Univ Calif Santa Cruz, Santa Cruz Inst Particle Phys, Dept Phys, Santa Cruz, CA 95064 USA. [Bouvier, A.; Ritz, S.; Sadrozinski, H. F. -W.; Schalk, T. L.; Ziegler, M.] Univ Calif Santa Cruz, Dept Astron & Astrophys, Santa Cruz, CA 95064 USA. [Brigida, M.; de Palma, F.; Favuzzi, C.; Fusco, P.; Giglietto, N.; Giordano, F.; Loparco, F.; Monte, C.; Raino, S.; Spinelli, P.] Univ & Politecn Bari, Dipartimento Fis M Merlin, I-70126 Bari, Italy. [Brigida, M.; de Palma, F.; Favuzzi, C.; Fusco, P.; Gargano, F.; Giglietto, N.; Giordano, F.; Loparco, F.; Mazziotta, M. N.; Monte, C.; Raino, S.; Spinelli, P.] Ist Nazl Fis Nucl, Sez Bari, I-70126 Bari, Italy. [Bruel, P.; Fegan, S. J.; Fortin, P.] Ecole Polytech, Lab Leprince Ringuet, CNRS IN2P3, Palaiseau, France. [Caliandro, G. A.; Hadasch, D.; Torres, D. F.] Inst Ciencies Espai IEEC CSIC, Barcelona 08193, Spain. [Caraveo, P. A.] INAF Ist Astrofis Spaziale & Fis Cosm, I-20133 Milan, Italy. [Chekhtman, A.] Artep Inc, Ellicott City, MD 21042 USA. [Cohen-Tanugi, J.; Mehault, J.; Nuss, E.; Pelassa, V.; Piron, F.; Vasileiou, V.] Univ Montpellier 2, Lab Univers & Particules Montpellier, CNRS IN2P3, Montpellier, France. [Conrad, J.; Yang, Z.] Stockholm Univ, Dept Phys, SE-10691 Stockholm, Sweden. [Conrad, J.; Yang, Z.] Oskar Klein Ctr Cosmoparticle Phys, SE-10691 Stockholm, Sweden. [Cutini, S.; Gasparrini, D.] Agenzia Spaziale Italiana ASI Sci Data Ctr, I-00044 Rome, Italy. [de Angelis, A.; Frailis, M.] Univ Udine, Dipartimento Fis, I-33100 Udine, Italy. [de Angelis, A.; Frailis, M.] Ist Nazl Fis Nucl, Sez Trieste, Grp Collegato Udine, I-33100 Udine, Italy. [Abdo, A. A.; Dermer, C. D.; Lovellette, M. N.; Strickman, M. S.; Wood, K. S.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. [Frailis, M.; Iafrate, G.] Ist Nazl Astrofis, Osservatorio Astron Trieste, I-34143 Trieste, Italy. [Gehrels, N.; Hays, E.; Johnson, T. J.; McEnery, J. E.; Moiseev, A. A.; Thompson, D. J.; Troja, E.] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA. [Giroletti, M.] INAF Ist Radioastron, I-40129 Bologna, Italy. [Guiriec, S.] Univ Alabama, CSPAR, Huntsville, AL 35899 USA. [Hughes, R. E.; Smith, P. D.; Winer, B. L.] Ohio State Univ, Dept Phys, Ctr Cosmol & Astroparticle Phys, Columbus, OH 43210 USA. [Johannesson, G.] Univ Iceland, Inst Sci, IS-107 Reykjavik, Iceland. [Johnson, T. J.; McEnery, J. E.; Moiseev, A. A.] Univ Maryland, Dept Phys, College Pk, MD 20742 USA. [Johnson, T. J.; McEnery, J. E.; Moiseev, A. A.; Share, G. H.] Univ Maryland, Dept Astron, College Pk, MD 20742 USA. [Katagiri, H.; Mizuno, T.] Hiroshima Univ, Dept Phys Sci, Hiroshima 7398526, Japan. [Kataoka, J.; Nakamori, T.] Waseda Univ, Res Inst Sci & Engn, Shinjuku Ku, Tokyo 1698555, Japan. [Knoedlseder, J.; Vilchez, N.] CNRS, IRAP, F-31028 Toulouse 4, France. [Knoedlseder, J.; Vilchez, N.] Univ Toulouse, UPS OMP, IRAP, Toulouse, France. [Lionetto, A. M.; Morselli, A.; Vitale, V.] Ist Nazl Fis Nucl, Sez Roma Tor Vergata, I-00133 Rome, Italy. [Lionetto, A. M.; Vitale, V.] Univ Roma Tor Vergata, Dipartimento Fis, I-00133 Rome, Italy. [Lott, B.; Reposeur, T.] Univ Bordeaux 1, CNRS IN2p3, Ctr Etud Nucl Bordeaux Gradignan, F-33175 Gradignan, France. [Moiseev, A. A.] NASA, CRESST, Greenbelt, MD 20771 USA. [Norris, J. P.; Ormes, J. F.] Univ Denver, Dept Phys & Astron, Denver, CO 80208 USA. [Ohsugi, T.; Takahashi, H.] Hiroshima Univ, Hiroshima Astrophys Sci Ctr, Hiroshima 7398526, Japan. [Okumura, A.; Ozaki, M.] JAXA, Inst Space & Astronaut Sci, Chuo Ku, Kanagawa 2525210, Japan. [Orlando, E.; Strong, A. W.] Max Planck Inst Extraterr Phys, D-85748 Garching, Germany. [Paneque, D.] Max Planck Inst Phys & Astrophys, D-80805 Munich, Germany. [Reimer, A.; Reimer, O.] Leopold Franzens Univ Innsbruck, Inst Astro & Teilchenphys, A-6020 Innsbruck, Austria. [Reimer, A.; Reimer, O.] Leopold Franzens Univ Innsbruck, Inst Theoret Phys, A-6020 Innsbruck, Austria. [Siskind, E. J.] NYCB Real Time Comp Inc, Lattingtown, NY 11560 USA. [Torres, D. F.] ICREA, Barcelona, Spain. [Tramacere, A.; Vianello, G.] CIFS, I-10133 Turin, Italy. [Tramacere, A.] INTEGRAL Sci Data Ctr, CH-1290 Versoix, Switzerland. RP Abdo, AA (reprint author), USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. EM brigida@ba.infn.it; nico.giglietto@ba.infn.it; imos@stanford.edu; eorlando@stanford.edu RI Johannesson, Gudlaugur/O-8741-2015; Loparco, Francesco/O-8847-2015; Gargano, Fabio/O-8934-2015; Moskalenko, Igor/A-1301-2007; Mazziotta, Mario /O-8867-2015; Sgro, Carmelo/K-3395-2016; Torres, Diego/O-9422-2016; Orlando, E/R-5594-2016; Morselli, Aldo/G-6769-2011; Thompson, David/D-2939-2012; Gehrels, Neil/D-2971-2012; McEnery, Julie/D-6612-2012; Baldini, Luca/E-5396-2012; lubrano, pasquale/F-7269-2012; Kuss, Michael/H-8959-2012; giglietto, nicola/I-8951-2012; Reimer, Olaf/A-3117-2013; Rando, Riccardo/M-7179-2013; Hays, Elizabeth/D-3257-2012; Funk, Stefan/B-7629-2015; Tosti, Gino/E-9976-2013; Ozaki, Masanobu/K-1165-2013 OI Tramacere, Andrea/0000-0002-8186-3793; Baldini, Luca/0000-0002-9785-7726; Sgro', Carmelo/0000-0001-5676-6214; Rando, Riccardo/0000-0001-6992-818X; Bastieri, Denis/0000-0002-6954-8862; Omodei, Nicola/0000-0002-5448-7577; Pesce-Rollins, Melissa/0000-0003-1790-8018; Giroletti, Marcello/0000-0002-8657-8852; Cutini, Sara/0000-0002-1271-2924; Berenji, Bijan/0000-0002-4551-772X; Gasparrini, Dario/0000-0002-5064-9495; Johannesson, Gudlaugur/0000-0003-1458-7036; Loparco, Francesco/0000-0002-1173-5673; Gargano, Fabio/0000-0002-5055-6395; Moskalenko, Igor/0000-0001-6141-458X; Mazziotta, Mario /0000-0001-9325-4672; Torres, Diego/0000-0002-1522-9065; Iafrate, Giulia/0000-0002-6185-8292; Giordano, Francesco/0000-0002-8651-2394; De Angelis, Alessandro/0000-0002-3288-2517; Frailis, Marco/0000-0002-7400-2135; Caraveo, Patrizia/0000-0003-2478-8018; Morselli, Aldo/0000-0002-7704-9553; Thompson, David/0000-0001-5217-9135; lubrano, pasquale/0000-0003-0221-4806; giglietto, nicola/0000-0002-9021-2888; Reimer, Olaf/0000-0001-6953-1385; Funk, Stefan/0000-0002-2012-0080; FU NASA [NNX10AD12G] FX The Fermi-LAT Collaboration acknowledges generous ongoing support from a number of agencies and institutes that have supported both the development and the operation of the Fermi-LAT as well as scientific data analysis. These include the National Aeronautics and Space Administration and the Department of Energy in the United States, the Commissariat a l'Energie Atomique and the Centre National de la Recherche Scientifique/Institut National de Physique Nucleaire et de Physique des Particules in France, the Agenzia Spaziale Italiana and the Istituto Nazionale di Fisica Nucleare in Italy, the Ministry of Education, Culture, Sports, Science and Technology (MEXT), High Energy Accelerator Research Organization (KEK) and Japan Aerospace Exploration Agency (JAXA) in Japan, and the K. A. Wallenberg Foundation, the Swedish Research Council and the Swedish National Space Board in Sweden. Additional support for science analysis during the operations phase is gratefully acknowledged from the Istituto Nazionale di Astrofisica in Italy and the Centre National d'Etudes Spatiales in France. I. V. M. and E.O. acknowledge support from NASA grant NNX10AD12G. NR 50 TC 34 Z9 34 U1 0 U2 7 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X J9 ASTROPHYS J JI Astrophys. J. PD JUN 20 PY 2011 VL 734 IS 2 AR 116 DI 10.1088/0004-637X/734/2/116 PG 10 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 774LD UT WOS:000291386500044 ER PT J AU Warren, HP Brooks, DH Winebarger, AR AF Warren, Harry P. Brooks, David H. Winebarger, Amy R. TI CONSTRAINTS ON THE HEATING OF HIGH-TEMPERATURE ACTIVE REGION LOOPS: OBSERVATIONS FROM HINODE AND THE SOLAR DYNAMICS OBSERVATORY SO ASTROPHYSICAL JOURNAL LA English DT Article DE Sun: corona ID ULTRAVIOLET IMAGING SPECTROMETER; X-RAY LOOPS; TRANSITION-REGION; CORONAL LOOPS; QUIET-SUN; PLASMA DIAGNOSTICS; EMISSION-LINES; MOSS; RESOLUTION; SPECTRA AB We present observations of high-temperature emission in the core of a solar active region using instruments on Hinode and the Solar Dynamics Observatory (SDO). These multi-instrument observations allow us to determine the distribution of plasma temperatures and follow the evolution of emission at different temperatures. We find that at the apex of the high-temperature loops the emission measure distribution is strongly peaked near 4MK and falls off sharply at both higher and lower temperatures. Perhaps most significantly, the emission measure at 0.5MK is reduced by more than two orders of magnitude from the peak at 4MK. We also find that the temporal evolution in broadband soft X-ray images is relatively constant over about 6 hr of observing. Observations in the cooler SDO/Atmospheric Imaging Assembly (AIA) bandpasses generally do not show cooling loops in the core of the active region, consistent with the steady emission observed at high temperatures. These observations suggest that the high-temperature loops observed in the core of an active region are close to equilibrium. We find that it is possible to reproduce the relative intensities of high-temperature emission lines with a simple, high-frequency heating scenario where heating events occur on timescales much less than a characteristic cooling time. In contrast, low-frequency heating scenarios, which are commonly invoked to describe nanoflare models of coronal heating, do not reproduce the relative intensities of high-temperature emission lines and predict low-temperature emission that is approximately an order of magnitude too large. We also present an initial look at images from the SDO/AIA 94 angstrom channel, which is sensitive to Fe XVIII. C1 [Warren, Harry P.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. [Brooks, David H.] George Mason Univ, Coll Sci, Fairfax, VA 22030 USA. [Winebarger, Amy R.] NASA, George C Marshall Space Flight Ctr, Huntsville, AL 35812 USA. RP Warren, HP (reprint author), USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. NR 52 TC 67 Z9 67 U1 0 U2 6 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X J9 ASTROPHYS J JI Astrophys. J. PD JUN 20 PY 2011 VL 734 IS 2 AR 90 DI 10.1088/0004-637X/734/2/90 PG 12 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 774LD UT WOS:000291386500018 ER PT J AU Lowrie, W Lukin, VS Shumlak, U AF Lowrie, W. Lukin, V. S. Shumlak, U. TI A priori mesh quality metric error analysis applied to a high-order finite element method SO JOURNAL OF COMPUTATIONAL PHYSICS LA English DT Article DE Finite element; Spectral element; Mesh deformation; Mesh quality metrics; MHD ID STIFFNESS MATRIX; CONDITION NUMBER AB Characterization of computational mesh's quality prior to performing a numerical simulation is an important step in insuring that the result is valid. A highly distorted mesh can result in significant errors. It is therefore desirable to predict solution accuracy on a given mesh. The HiFi/SEL high-order finite element code is used to study the effects of various mesh distortions on solution quality of known analytic problems for spatial discretizations with different order of finite elements. The measured global error norms are compared to several mesh quality metrics by independently varying both the degree of the distortions and the order of the finite elements. It is found that the spatial spectral convergence rates are preserved for all considered distortion types, while the total error increases with the degree of distortion. For each distortion type, correlations between the measured solution error and the different mesh metrics are quantified, identifying the most appropriate overall mesh metric. The results show promise for future a priori computational mesh quality determination and improvement. (C) 2011 Elsevier Inc. All rights reserved. C1 [Lowrie, W.; Shumlak, U.] Univ Washington, Plasma Sci & Innovat Ctr, Seattle, WA 98195 USA. [Lukin, V. S.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. RP Lowrie, W (reprint author), Univ Washington, Plasma Sci & Innovat Ctr, Box 352250, Seattle, WA 98195 USA. EM wlowrie@uw.edu OI Shumlak, Uri/0000-0002-2918-5446 FU US Department of Energy; Office of Naval Research FX This research was supported by the US Department of Energy and the Office of Naval Research. Special thanks to Alan Glasser, Ulrich Hetmaniuk, and Eric Meier for their help and advice with this research. NR 17 TC 3 Z9 3 U1 0 U2 7 PU ACADEMIC PRESS INC ELSEVIER SCIENCE PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA SN 0021-9991 J9 J COMPUT PHYS JI J. Comput. Phys. PD JUN 20 PY 2011 VL 230 IS 14 BP 5564 EP 5586 DI 10.1016/j.jcp.2011.03.036 PG 23 WC Computer Science, Interdisciplinary Applications; Physics, Mathematical SC Computer Science; Physics GA 774GP UT WOS:000291374000006 ER PT J AU Montes, MA Churnside, J Lee, Z Gould, R Arnone, R Weidemann, A AF Montes, Martin A. Churnside, James Lee, Zhongping Gould, Richard Arnone, Robert Weidemann, Alan TI Relationships between water attenuation coefficients derived from active and passive remote sensing: a case study from two coastal environments SO APPLIED OPTICS LA English DT Article ID OCEAN COLOR; OPTICAL-PROPERTIES; OCEANOGRAPHIC LIDAR; SCATTERING; MODEL; UNCERTAINTIES; IRRADIANCE; ALGORITHM; RADIATION; INHERENT AB Relationships between the satellite-derived diffuse attenuation coefficient of downwelling irradiance (K-d) and airborne-based vertical attenuation of lidar volume backscattering (alpha) were examined in two coastal environments. At 1.1 km resolution and a wavelength of 532 nm, we found a greater connection between alpha and K-d when alpha was computed below 2 m depth (Spearman rank correlation coefficient up to 0.96), and a larger contribution of K-d to alpha with respect to the beam attenuation coefficient as estimated from lidar measurements and K-d models. Our results suggest that concurrent passive and active optical measurements can be used to estimate total scattering coefficient and backscattering efficiency in waters without optical vertical structure. (C) 2011 Optical Society of America C1 [Montes, Martin A.; Lee, Zhongping] Mississippi State Univ, Geosyst Res Inst, Mississippi State, MS 39529 USA. [Gould, Richard; Arnone, Robert; Weidemann, Alan] USN, Res Lab, Stennis Space Ctr, NASA, Stennis Space Ctr, MS 39529 USA. [Churnside, James] Natl Ocean & Atmospher Adm, Earth Syst Res Lab, Boulder, CO 80305 USA. RP Montes, MA (reprint author), Mississippi State Univ, Geosyst Res Inst, Mississippi State, MS 39529 USA. EM mmontes@gri.msstate.edu RI Churnside, James/H-4873-2013; Manager, CSD Publications/B-2789-2015 FU Naval Research Laboratory (NRL) [PBE0601153N] FX This work was supported by the Naval Research Laboratory (NRL) internal project "3D Remote Sensing with a Multiple-Band Active and Passive System: Theoretical Basis," PBE0601153N. NR 32 TC 5 Z9 5 U1 0 U2 10 PU OPTICAL SOC AMER PI WASHINGTON PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA SN 1559-128X EI 2155-3165 J9 APPL OPTICS JI Appl. Optics PD JUN 20 PY 2011 VL 50 IS 18 BP 2990 EP 2999 DI 10.1364/AO.50.002990 PG 10 WC Optics SC Optics GA 781WN UT WOS:000291968500024 PM 21691366 ER PT J AU Seely, J Kjornrattanawanich, B Goray, L Feng, Y Bremer, J AF Seely, John Kjornrattanawanich, Benjawan Goray, Leonid Feng, Yan Bremer, James TI Characterization of zone plate properties using monochromatic synchrotron radiation in the 2 to 20 nm wavelength range SO APPLIED OPTICS LA English DT Article ID EFFICIENCIES; GRATINGS AB A zone plate composed of Mo zones having 4 mm outermost zone diameter, 100 nm outermost zone width, and supported on a silicon nitride membrane was characterized using monochromatic synchrotron radiation in the 2 to 20 nm wavelength range. The zero and first order efficiencies were measured and compared to ab initio calculations that account for the optical properties of the materials, the width and shape of the zones, and multiple-layer thin-film effects. It is shown that the thicknesses of the Mo zones and the membrane and the ratio of the zone width to zone period can be independently determined from the measured diffraction efficiencies in the zero and first orders and that the computational code can be used to reliably design zone plates that are optimized for applications such as solar irradiance monitors in the extreme ultraviolet region. C1 [Seely, John] USN, Res Lab, Washington, DC 20375 USA. [Kjornrattanawanich, Benjawan] Artep Inc, Ellicott City, MD 21042 USA. [Kjornrattanawanich, Benjawan] Brookhaven Natl Lab, Natl Synchrotron Light Source Beamline X24C, Upton, NY 11973 USA. [Goray, Leonid] Russian Acad Sci, St Petersburg Acad Univ, St Petersburg 194021, Russia. [Goray, Leonid] Russian Acad Sci, Inst Analyt Instrumentat, St Petersburg 190103, Russia. [Feng, Yan] Xradia Inc, Pleasanton, CA 94588 USA. [Bremer, James] Res Support Instruments Inc, Lanham, MD 20706 USA. RP Seely, J (reprint author), USN, Res Lab, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM john.seely@nrl.navy.mil RI Goray, Leonid/D-4426-2013 OI Goray, Leonid/0000-0002-0381-9607 FU NASA; Office of Naval Research (ONR) FX This work was supported by the NASA project Ultra-Stable Extreme Ultraviolet Solar Monitor using Zone Plates and by the Office of Naval Research (ONR). NR 10 TC 1 Z9 1 U1 0 U2 1 PU OPTICAL SOC AMER PI WASHINGTON PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA SN 1559-128X EI 2155-3165 J9 APPL OPTICS JI Appl. Optics PD JUN 20 PY 2011 VL 50 IS 18 BP 3015 EP 3020 DI 10.1364/AO.50.003015 PG 6 WC Optics SC Optics GA 781WN UT WOS:000291968500027 PM 21691369 ER PT J AU Hoheisel, R Schachtner, M Stammler, E Bett, AW AF Hoheisel, R. Schachtner, M. Staemmler, E. Bett, A. W. TI Determination of the subcell photovoltage in multijunction solar cells via voltage-dependent capacitance analysis SO APPLIED PHYSICS LETTERS LA English DT Article DE aluminium compounds; capacitance; elemental semiconductors; Fermi level; gallium arsenide; gallium compounds; germanium; III-V semiconductors; indium compounds; solar cells; wide band gap semiconductors AB The letter describes a method for determining the photovoltage, i.e., the quasifermi level splitting at open-circuit conditions, associated with each subcell in a series connected multijunction solar cell structure by voltage-dependent capacitance analysis. Experimental verification and accuracy analysis of subcell photovoltage determination is provided for a 6-tuple AlGaInP/GaInP/AlGaInAs/GaInAs/GaInNAs/Ge solar cell device. (C) 2011 American Institute of Physics. [doi:10.1063/1.3601468] C1 [Hoheisel, R.; Schachtner, M.; Staemmler, E.; Bett, A. W.] Fraunhofer Inst Solar Energy Syst, D-79110 Freiburg, Germany. RP Hoheisel, R (reprint author), USN, Res Lab, 4555 Overlook Ave SE, Washington, DC 20375 USA. EM raymond.hoheisel@ise.fraunhofer.de NR 12 TC 5 Z9 5 U1 0 U2 14 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD JUN 20 PY 2011 VL 98 IS 25 AR 251106 DI 10.1063/1.3601468 PG 3 WC Physics, Applied SC Physics GA 782VE UT WOS:000292039900006 ER PT J AU Wilhelm, K Abbo, L Auchere, F Barbey, N Feng, L Gabriel, AH Giordano, S Imada, S Llebaria, A Matthaeus, WH Poletto, G Raouafi, NE Suess, ST Teriaca, L Wang, YM AF Wilhelm, K. Abbo, L. Auchere, F. Barbey, N. Feng, L. Gabriel, A. H. Giordano, S. Imada, S. Llebaria, A. Matthaeus, W. H. Poletto, G. Raouafi, N. -E. Suess, S. T. Teriaca, L. Wang, Y. -M. TI Morphology, dynamics and plasma parameters of plumes and inter-plume regions in solar coronal holes SO ASTRONOMY AND ASTROPHYSICS REVIEW LA English DT Review DE Sun; Corona; Coronal holes; Coronal plumes; Inter-plume regions; Solar wind ID EXTREME-ULTRAVIOLET OBSERVATIONS; SLOW MAGNETOSONIC WAVES; R-CIRCLE-DOT; MAGNETOHYDRODYNAMIC TURBULENCE DRIVEN; PRESSURE BALANCE STRUCTURES; EUV IMAGING SPECTROMETER; POLAR PLUMES; WHITE-LIGHT; TRANSITION-REGION; QUIET-SUN AB Coronal plumes, which extend from solar coronal holes (CH) into the high corona and-possibly-into the solar wind (SW), can now continuously be studied with modern telescopes and spectrometers on spacecraft, in addition to investigations from the ground, in particular, during total eclipses. Despite the large amount of data available on these prominent features and related phenomena, many questions remained unanswered as to their generation and relative contributions to the high-speed streams emanating from CHs. An understanding of the processes of plume formation and evolution requires a better knowledge of the physical conditions at the base of CHs, in plumes and in the surrounding inter-plume regions. More specifically, information is needed on the magnetic field configuration, the electron densities and temperatures, effective ion temperatures, non-thermal motions, plume cross sections relative to the size of a CH, the plasma bulk speeds, as well as any plume signatures in the SW. In spring 2007, the authors proposed a study on 'Structure and dynamics of coronal plumes and inter-plume regions in solar coronal holes' to the International Space Science Institute (ISSI) in Bern to clarify some of these aspects by considering relevant observations and the extensive literature. This review summarizes the results and conclusions of the study. Stereoscopic observations allowed us to include three-dimensional reconstructions of plumes. Multi-instrument investigations carried out during several campaigns led to progress in some areas, such as plasma densities, temperatures, plume structure and the relation to other solar phenomena, but not all questions could be answered concerning the details of plume generation process(es) and interaction with the SW. C1 [Wilhelm, K.; Feng, L.; Teriaca, L.] Max Planck Inst Sonnensyst Forsch, D-37191 Katlenburg Lindau, Germany. [Feng, L.] Chinese Acad Sci, Purple Mt Observ, Nanjing 210008, Peoples R China. [Abbo, L.; Giordano, S.] INAF Osservatorio Astron Torino, I-10025 Pino Torinese, Italy. [Auchere, F.; Barbey, N.; Gabriel, A. H.] Univ Paris 11, Inst Astrophys Spatiale, F-91405 Orsay, France. [Imada, S.] Japan Aerosp Explorat Agcy, Inst Space & Astronaut Sci, Sagamihara, Kanagawa 2298510, Japan. [Llebaria, A.] Observ Astron Marseille Prov, Lab Astrophys Marseille, F-13388 Marseille 13, France. [Matthaeus, W. H.] Univ Delaware, Bartol Res Inst, Dept Phys & Astron, Newark, DE USA. [Poletto, G.] Osserv Astrofis Arcetri, I-50125 Florence, Italy. [Raouafi, N. -E.] Johns Hopkins Univ, Appl Phys Lab, Laurel, MD 20723 USA. [Suess, S. T.] Natl Space Sci & Technol Ctr, Huntsville, AL 35805 USA. [Wang, Y. -M.] USN, Code 7672, EO Hulburt Ctr Space Res, Res Lab, Washington, DC 20375 USA. RP Wilhelm, K (reprint author), Max Planck Inst Sonnensyst Forsch, D-37191 Katlenburg Lindau, Germany. EM wilhelm@mps.mpg.de RI Feng, Li/G-2100-2015; Raouafi, Nour/C-2286-2016; Raouafi, Noureddine/G-4062-2010; OI Giordano, Silvio/0000-0002-3468-8566; Raouafi, Nour/0000-0003-2409-3742; Raouafi, Noureddine/0000-0001-8938-8221; Auchere, Frederic/0000-0003-0972-7022; Abbo, Lucia/0000-0001-8235-2242 FU International Space Science Institute; Italian Space Agency [ASI/I015/07/0] FX We dedicate this article to the memory of Sir William Ian Axford who was very interested in coronal plumes and their relation to the fast solar wind. The team members thank the International Space Science Institute for the opportunity to conduct this work within the International Study Team programme and the financial support. During two sessions in Bern, we enjoyed the hospitality and the excellent working conditions at the institute. We also want to thank the SOHO, TRACE, Hinode and STEREO teams. Without their work we could not have conducted this study. We acknowledge the analysis of the XRT data discussed here by Giulia Schettino and Alphonse Sterling, the comments on a draft version of the manuscript by EckartMarsch and the review of the referee. GP is grateful for support from the Italian Space Agency (ASI/I015/07/0). SI thanks Saku Tsuneta for fruitful discussions about the magnetic fields in polar regions. NR 237 TC 31 Z9 31 U1 1 U2 9 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 0935-4956 J9 ASTRON ASTROPHYS REV JI Astron. Astrophys. Rev. PD JUN 16 PY 2011 VL 19 BP 1 EP 70 AR 35 DI 10.1007/s00159-011-0035-7 PG 70 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 834PZ UT WOS:000295976300001 ER PT J AU Berger, EL Zega, TJ Keller, LP Lauretta, DS AF Berger, Eve L. Zega, Thomas J. Keller, Lindsay P. Lauretta, Dante S. TI Evidence for aqueous activity on comet 81P/Wild 2 from sulfide mineral assemblages in Stardust samples and CI chondrites SO GEOCHIMICA ET COSMOCHIMICA ACTA LA English DT Article ID INTERPLANETARY DUST PARTICLES; TRANSMISSION ELECTRON-MICROSCOPY; IRON-NICKEL SULFIDES; SOLAR NEBULA; CARBONACEOUS CHONDRITES; PYRRHOTITE SUPERSTRUCTURES; CRYSTAL-STRUCTURE; PARENT BODY; CUBANITE; SYSTEM AB The discovery of nickel-, copper-, and zinc-bearing iron sulfides from comet 81P/Wild 2 (Wild 2) represents the strongest evidence, in the Stardust collection, of grains that formed in an aqueous environment. We investigated three microtomed TEM sections which contain crystalline sulfide assemblages from Wild 2 and twelve thin sections of the hydrothermally altered CI chondrite Orgueil. Detailed structural and compositional characterizations of the sulfide grains from both collections reveal striking similarities. The Stardust samples include a cubanite (CuFe2S3) grain, a pyrrhotite [(Fe,Ni)(1-x)S]/pentlandite [(Fe, Ni)(9)S-8] assemblage, and a pyrrhotite/sphalerite [(Fe, Zn)S] assemblage. Similarly, the CI-chondrite sulfides include individual cubanite and pyrrhotite grains, cubanite/pyrrhotite assemblages, pyrrhotite/pentlandite assemblages, as well as possible sphalerite inclusions within pyrrhotite grains. The cubanite is the low temperature orthorhombic form, which constrains temperature to a maximum of 210 degrees C. The Stardust and Orgueil pyrrhotites are the 4C monoclinic polytype, which is not stable above similar to 250 degrees C. The combinations of cubanite and pyrrhotite, as well as pyrrhotite and pentlandite signify even lower temperatures. The crystal structures, compositions, and petrographic relationships of these sulfides constrain formation and alteration conditions. Taken together, these constraints attest to low-temperature hydrothermal processing. Our analyses of these minerals provide constraints on large scale issues such as: heat sources in the comet-forming region; aqueous activity on cometary bodies; and the extent and mechanisms of radial mixing of material in the early nebula. The sulfides in the Wild 2 collection are most likely the products of low-temperature aqueous alteration. They provide evidence of radial mixing of material (e. g. cubanite, troilite) from the inner solar system to the comet-forming region and possible secondary aqueous processing on the cometary body. (C) 2011 Elsevier Ltd. All rights reserved. C1 [Berger, Eve L.; Lauretta, Dante S.] Univ Arizona, Lunar & Planetary Lab, Tucson, AZ 85721 USA. [Zega, Thomas J.] USN, Res Lab, Washington, DC 20375 USA. [Keller, Lindsay P.] NASA, Lyndon B Johnson Space Ctr, Houston, TX 77058 USA. RP Berger, EL (reprint author), Univ Arizona, Lunar & Planetary Lab, Tucson, AZ 85721 USA. EM elberger@lpl.arizona.edu FU NASA [NNX08AW48H, NNH08AH58I, 06-SSAP06-0026, NNX09AC60G] FX Special thanks to G. Consolmagno and the Vatican Observatory for providing samples of Orgueil. We thank D. Brownlee, D. Joswiak and G. Matrajt, at the University of Washington; K. Nakamura-Messenger for assistance in Stardust sample selection; and CAPTEM for providing Stardust samples; Emma Bullock, Hughes Leroux, and an anonymous referee for constructive reviews; and Associate Editor, Sara Russell, for helpful comments. This work was supported by NASA grants: NNX08AW48H (ELB), NNH08AH58I (Rhonda Stroud PI, TJZ Co-I), 06-SSAP06-0026 (Scott Messenger PI, LPK Co-I), and NNX09AC60G (DSL PI). NR 98 TC 43 Z9 43 U1 2 U2 9 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0016-7037 J9 GEOCHIM COSMOCHIM AC JI Geochim. Cosmochim. Acta PD JUN 15 PY 2011 VL 75 IS 12 BP 3501 EP 3513 DI 10.1016/j.gca.2011.03.026 PG 13 WC Geochemistry & Geophysics SC Geochemistry & Geophysics GA 796YD UT WOS:000293088500012 ER PT J AU Garces, NY Wheeler, VD Hite, JK Jernigan, GG Tedesco, JL Nepal, N Eddy, CR Gaskill, DK AF Garces, N. Y. Wheeler, V. D. Hite, J. K. Jernigan, G. G. Tedesco, J. L. Nepal, Neeraj Eddy, C. R., Jr. Gaskill, D. K. TI Epitaxial graphene surface preparation for atomic layer deposition of Al2O3 SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID RAY PHOTOELECTRON-SPECTROSCOPY; GATE DIELECTRICS; WAFER-SCALE; FILMS; TRANSISTORS; CHEMISTRY; GROWTH; GAS; XPS AB Atomic layer deposition was employed to deposit relatively thick (similar to 30 nm) aluminum oxide (Al2O3) using trimethylaluminum and triply-distilled H2O precursors onto epitaxial graphene grown on the Si-face of silicon carbide. Ex situ surface conditioning by a simple wet chemistry treatment was used to render the otherwise chemically inert graphene surface more amenable to dielectric deposition. The obtained films show excellent morphology and uniformity over large (similar to 64 mm(2)) areas (i.e., the entire sample area), as determined by atomic force microscopy and scanning electron microscopy. X-ray photoelectron spectroscopy revealed a nearly stoichiometric film with reduced impurity content. Moreover, from capacitance-voltage measurements a dielectric constant of similar to 7.6 was extracted and a positive Dirac voltage shift of similar to 1.0 V was observed. The graphene mobility, as determined by van der Pauw Hall measurements, was not affected by the sequence of surface pretreatment and dielectric deposition. (C) 2011 American Institute of Physics. [doi:10.1063/1.3596761] C1 [Garces, N. Y.] North Amer, Global Strategies Grp, Crofton, MD 21114 USA. [Garces, N. Y.; Wheeler, V. D.; Hite, J. K.; Jernigan, G. G.; Tedesco, J. L.; Nepal, Neeraj; Eddy, C. R., Jr.; Gaskill, D. K.] USN, Res Lab, Washington, DC 20375 USA. RP Garces, NY (reprint author), North Amer, Global Strategies Grp, 2200 Def Hwy,Suite 405, Crofton, MD 21114 USA. EM nelson.garces@nrl.navy.mil RI Hite, Jennifer/L-5637-2015 OI Hite, Jennifer/0000-0002-4090-0826 FU American Society for Engineering Education Naval Research Laboratory; Office of Naval Research FX The authors thank Paul E. Sheehan for kindly providing access to his spectroscopic ellipsometer and for helpful suggestions fitting the data. J.L.T., V.D.W., and J.K.H. acknowledge the support of the American Society for Engineering Education Naval Research Laboratory Postdoctoral Fellowship Program. Work at the U.S. Naval Research Laboratory is supported by the Office of Naval Research. NR 32 TC 24 Z9 24 U1 2 U2 61 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0021-8979 J9 J APPL PHYS JI J. Appl. Phys. PD JUN 15 PY 2011 VL 109 IS 12 AR 124304 DI 10.1063/1.3596761 PG 6 WC Physics, Applied SC Physics GA 786TQ UT WOS:000292331200119 ER PT J AU Hwang, PF Porterfield, N Pannell, D Davis, TA Elster, EA AF Hwang, Paul F. Porterfield, Nancy Pannell, Dylan Davis, Thomas A. Elster, Eric A. TI Trauma is danger SO JOURNAL OF TRANSLATIONAL MEDICINE LA English DT Review ID TUMOR-NECROSIS-FACTOR; GROUP BOX-1 PROTEIN; ACUTE LUNG INJURY; IMMUNE-SYSTEM; SEPTIC SHOCK; ANTIINFLAMMATORY THERAPIES; EXTRACELLULAR HSP72; STRUCTURAL BASIS; INNATE IMMUNITY; SERUM-LEVELS AB Background: Trauma is one of the leading causes of death in young adult patients. Many pre-clinical and clinical studies attempt to investigate the immunological pathways involved, however the true mediators remain to be elucidated. Herein, we attempt to describe the immunologic response to systemic trauma in the context of the Danger model. Data Sources: A literature search using PubMed was used to identify pertinent articles describing the Danger model in relation to trauma. Conclusions: Our knowledge of Danger signals in relation to traumatic injury is still limited. Danger/alarmin signals are the most proximal molecules in the immune response that have many possibilities for effector function in the innate and acquired immune systems. Having a full understanding of these molecules and their pathways would give us the ability to intervene at such an early stage and may prove to be more effective in blunting the post-injury inflammatory response unlike previously failed cytokine experiments. C1 [Hwang, Paul F.; Porterfield, Nancy; Davis, Thomas A.; Elster, Eric A.] USN, Regenerat Med Dept, Med Res Ctr, Silver Spring, MD USA. [Hwang, Paul F.; Elster, Eric A.] Walter Reed Natl Mil Med Ctr, Dept Surg, Gen Surg Serv, Bethesda, MD USA. [Hwang, Paul F.; Elster, Eric A.] Uniformed Serv Univ Hlth Sci, Dept Surg, Bethesda, MD 20814 USA. [Pannell, Dylan] Canadian Forces Hlth Serv, Dept Natl Defense, Ottawa, ON, Canada. [Pannell, Dylan] Univ Toronto, Dept Surg, Toronto, ON M5S 1A1, Canada. RP Elster, EA (reprint author), USN, Regenerat Med Dept, Med Res Ctr, Silver Spring, MD USA. EM eric.elster1@med.navy.mil FU U.S. Navy Bureau of Medicine and Surgery; Office of Naval Research [604771N.0933.001.A0604] FX This effort was supported (in part) by the U.S. Navy Bureau of Medicine and Surgery under the Medical Development Program and Office of Naval Research work unit number (604771N.0933.001.A0604). NR 73 TC 11 Z9 12 U1 0 U2 1 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1479-5876 J9 J TRANSL MED JI J. Transl. Med. PD JUN 15 PY 2011 VL 9 AR 92 DI 10.1186/1479-5876-9-92 PG 10 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA 789LA UT WOS:000292515800001 PM 21676213 ER PT J AU Sapsford, KE Tyner, KM Dair, BJ Deschamps, JR Medintz, IL AF Sapsford, Kim E. Tyner, Katherine M. Dair, Benita J. Deschamps, Jeffrey R. Medintz, Igor L. TI Analyzing Nanomaterial Bioconjugates: A Review of Current and Emerging Purification and Characterization Techniques SO ANALYTICAL CHEMISTRY LA English DT Review ID FIELD-FLOW FRACTIONATION; DYNAMIC LIGHT-SCATTERING; RESONANCE ENERGY-TRANSFER; FLUORESCENCE CORRELATION SPECTROSCOPY; ATOMIC-FORCE MICROSCOPY; SOLID LIPID NANOPARTICLES; WALLED CARBON NANOTUBES; X-RAY-SCATTERING; QUANTUM DOTS; GOLD NANOPARTICLES C1 [Sapsford, Kim E.] US FDA, Div Biol, Off Sci & Engn Labs, Ctr Devices & Radiol Hlth, Silver Spring, MD 20993 USA. [Tyner, Katherine M.] US FDA, Div Drug Safety Res, Off Testing & Res, Off Pharmaceut Sci,Ctr Drug Evaluat & Res, Silver Spring, MD 20993 USA. [Dair, Benita J.] US FDA, Div Chem & Mat Sci, Off Sci & Engn Labs, Ctr Devices & Radiol Hlth, Silver Spring, MD 20993 USA. [Deschamps, Jeffrey R.; Medintz, Igor L.] USN, Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. RP Sapsford, KE (reprint author), US FDA, Div Biol, Off Sci & Engn Labs, Ctr Devices & Radiol Hlth, 10903 New Hampshire Ave, Silver Spring, MD 20993 USA. EM Kim.Sapsford@fda.hhs.gov; Igor.Medintz@nrl.navy.mil OI Deschamps, Jeffrey/0000-0001-5845-0010 FU NRL-NSI; ONR; DTRA; DARPA FX I.L.M. and K.E.S thank F. Ligler at NRL for initial encouragement. I.L.M. acknowledges the NRL-NSI, ONR, DTRA, and DARPA for financial support. K.E.S would like to thank Dr. T. Umbreit and Dr. B. Casey (FDA) for their helpful comments during the preparation of this manuscript. This paper reflects the current thinking and experience of the authors. No official support or endorsement by the U.S. Food and Drug Administration is intended or should be inferred. NR 261 TC 137 Z9 137 U1 7 U2 166 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0003-2700 EI 1520-6882 J9 ANAL CHEM JI Anal. Chem. PD JUN 15 PY 2011 VL 83 IS 12 BP 4453 EP 4488 DI 10.1021/ac200853a PG 36 WC Chemistry, Analytical SC Chemistry GA 775YP UT WOS:000291499800008 PM 21545140 ER PT J AU Field, CR In, HJ Begue, NJ Pehrsson, PE AF Field, Christopher R. In, Hyun Jin Begue, Nathan J. Pehrsson, Pehr E. TI Vapor Detection Performance of Vertically Aligned, Ordered Arrays of Silicon Nanowires with a Porous Electrode SO ANALYTICAL CHEMISTRY LA English DT Article ID WALLED CARBON NANOTUBES; CHEMICAL WARFARE AGENTS; SENSORS; DEVICES AB Vertically aligned, ordered arrays of silicon nanowires capped with a porous top electrode are used to detect gas phase ammonia and nitrogen dioxide in humidified air. The sensors had very fast response times and large signal-to-noise ratios. Calibration curves were created using both an initial slope method and a fixed-time point method. The initial-slope method had a power law dependence that correlates well with concentration, demonstrating a viable alternative for eventual quantitative vapor detection and enabling shorter sampling and regeneration times. C1 [Field, Christopher R.; Pehrsson, Pehr E.] USN, Res Lab, Div Chem, Washington, DC 20375 USA. [In, Hyun Jin; Begue, Nathan J.] CNR, Washington, DC 20001 USA. RP Field, CR (reprint author), USN, Res Lab, Div Chem, Washington, DC 20375 USA. EM christopher.field@nrl.navy.mil FU Defense Threat Reduction Agency FX The authors would like to acknowledge Michael Malito, Dr. Cy Tamanaha, and Dr. Susan Rose-Pehrsson for their efforts in constructing the vapor delivery system and modeling of the conical sample chamber, respectively. We would also like to thank Mark Hammond for his work on the computer interface connected to the vapor delivery system. This work was funded in part by the Defense Threat Reduction Agency. All fabrication was carried out in the Naval Research Laboratory's Nanoscience Institute. NR 28 TC 14 Z9 14 U1 2 U2 32 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0003-2700 EI 1520-6882 J9 ANAL CHEM JI Anal. Chem. PD JUN 15 PY 2011 VL 83 IS 12 BP 4724 EP 4728 DI 10.1021/ac200779d PG 5 WC Chemistry, Analytical SC Chemistry GA 775YP UT WOS:000291499800019 PM 21563827 ER PT J AU Hirschel, M Gangemi, JD McSharry, J Myers, C AF Hirschel, Mark Gangemi, J. David McSharry, James Myers, Chris TI Novel Uses for Hollow Fiber Bioreactors SO GENETIC ENGINEERING & BIOTECHNOLOGY NEWS LA English DT Article C1 [Hirschel, Mark; Gangemi, J. David] Biovest Int, Tampa, FL 33606 USA. [McSharry, James] Ordway Res Inst, Albany, NY USA. [Myers, Chris] Naval Hlth Res Ctr, Dept Resp Dis Res, San Diego, CA USA. RP Hirschel, M (reprint author), Biovest Int, Tampa, FL 33606 USA. EM mhirschel@biovest.com NR 0 TC 3 Z9 3 U1 0 U2 0 PU MARY ANN LIEBERT INC PI NEW ROCHELLE PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA SN 1935-472X J9 GENET ENG BIOTECHN N JI Genet. Eng. Biotechnol. News PD JUN 15 PY 2011 VL 31 IS 12 BP 42 EP + PG 2 WC Biotechnology & Applied Microbiology; Genetics & Heredity SC Biotechnology & Applied Microbiology; Genetics & Heredity GA 779EZ UT WOS:000291762200012 ER PT J AU Davis, TA O'Brien, FP Anam, K Grijalva, S Potter, BK Elster, EA AF Davis, Thomas A. O'Brien, Frederick P. Anam, Khairul Grijalva, Steven Potter, Benjamin K. Elster, Eric A. TI Heterotopic Ossification in Complex Orthopaedic Combat Wounds Quantification and Characterization of Osteogenic Precursor Cell Activity in Traumatized Muscle SO JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME LA English DT Article ID MESENCHYMAL STEM-CELLS; HUMAN BONE-MARROW; MATRIX-MEDIATED RETENTION; EX-VIVO EXPANSION; TRANSCRIPTION FACTORS; ADIPOSE-TISSUE; STROMAL CELLS; SHEAR-STRESS; RISK-FACTORS; DIFFERENTIATION AB Background: Heterotopic ossification frequently develops following high-energy blast injuries sustained in modern warfare. We hypothesized that differences,in the population of progenitor cells present in a wound would correlate with the subsequent formation of heterotopic ossification. Methods: We obtained muscle biopsy specimens from military service members who had sustained high-energy wartime injuries and from patients undergoing harvest of a hamstring tendon autograft. Plastic-adherent cells were isolated in single-cell suspension and plated to assess the prevalence of colony-forming cells. Phenotypic characteristics were assessed with use of flow cytometry. Individual colony-forming units were counted after an incubation period of seven to ten days, and replicate cultures were incubated in lineage-specific induction media. Immunohistochemical staining was then performed to determine the percentage of colonies that had differentiated along an osteogenic lineage. Quantitative real-time reverse-transcription polymerase chain reaction was used to identify changes in osteogenic gene expression. Results: Injured patients had significantly higher numbers of muscle-derived connective-tissue progenitor cells per gram of tissue (p < 0.0001; 95% confidence interval [CI], 129,930 to 253,333), and those who developed heterotopic ossification had higher numbers of assayable osteogenic colonies (p < 0.016; 95% CI, 12,249 to 106,065). In the injured, group, quantitative real-time reverse-transcription polymerase chain reaction performed on the in vitro expanded progeny of connective-tissue progenitors demonstrated upregulation of COL10A1, COL4A3, COMP, FGFR2, FLT1, IGF2, ITGAM, MMP9, PHEX, SCARB1, SOX9, and VEGFA in the patients with heterotopic ossification as compared with those without heterotopic ossification. Conclusions: Our study suggests that the number of connective-tissue progenitor cells is increased in traumatized tissue. Furthermore, wounds in which heterotopic ossification eventually forms have a higher percentage of connective-tissue progenitor cells committed to osteogenic differentiation than do wounds in which heterotopic ossification does not form. The early identification of heterotopic ossification-precursor cells and target genes in severe wounds not only may be an effective prognostic tool with which to assess whether heterotopic ossification will develop in a wound, but may also guide the future development of individualized prophylactic measures. C1 [Davis, Thomas A.; Anam, Khairul] USN, Regenerat Med Dept, Med Res Ctr, Silver Spring, MD 20910 USA. [O'Brien, Frederick P.; Grijalva, Steven; Potter, Benjamin K.; Elster, Eric A.] Walter Reed Natl Mil Med Ctr, Bethesda, MD 20889 USA. RP Davis, TA (reprint author), USN, Regenerat Med Dept, Med Res Ctr, Room 2A10,503 Robert Grant Ave, Silver Spring, MD 20910 USA. EM thomas.davis1@med.navy.mil FU Office of Naval Research; U.S. Navy Bureau of Medicine and Surgery under the Medical Development [601152N.00001.2130.A1001, 6011771N.0933.001.A0604] FX This work was supported by the Office of Naval Research and U.S. Navy Bureau of Medicine and Surgery under the Medical Development work unit numbers 601152N.00001.2130.A1001 and 6011771N.0933.001.A0604. NR 37 TC 34 Z9 34 U1 0 U2 4 PU JOURNAL BONE JOINT SURGERY INC PI NEEDHAM PA 20 PICKERING ST, NEEDHAM, MA 02192 USA SN 0021-9355 J9 J BONE JOINT SURG AM JI J. Bone Joint Surg.-Am. Vol. PD JUN 15 PY 2011 VL 93A IS 12 BP 1122 EP 1131 DI 10.2106/JBJSJ.01417 PG 10 WC Orthopedics; Surgery SC Orthopedics; Surgery GA 777LX UT WOS:000291623400005 PM 21776549 ER PT J AU Sheremet, A Jaramillo, S Su, SF Allison, MA Holland, KT AF Sheremet, A. Jaramillo, S. Su, S-F. Allison, M. A. Holland, K. T. TI Wave-mud interaction over the muddy Atchafalaya subaqueous clinoform, Louisiana, United States: Wave processes SO JOURNAL OF GEOPHYSICAL RESEARCH-OCEANS LA English DT Article ID SOUTHWEST COAST; SHALLOW-WATER; SURFACE-WAVES; MODEL; SHELF; MUDBANKS; INDIA; DISSIPATION; ATTENUATION; EVOLUTION AB Observations of wave and sediment processes collected at two locations on the Atchafalaya inner shelf show that wave dissipation in shallow, muddy environments is strongly coupled to bed-sediment reworking by waves. During an energetic wave event (2 m significant wave height in 5 m water depth), acoustic backscatter records suggest that sediment in the surficial bed layer evolves from consolidated mud through liquefaction, fluid mud formation, and hindered settling to gelled, under-consolidated mud. Net swell dissipation increases steadily during the storm from negligible prestorm values, consistent with bed softening, but shows no correlation with detectable fluid mud layers. Remarkably, the maximum dissipation rate occurs poststorm, when no fluid mud layers are present. In the waning stage of the storm, the contribution of different wave-forcing processes to wave dissipation is analyzed using an inverse modeling approach based on a nonlinear three-wave interaction model. Although wave-mud interaction dominates dissipative processes, nonlinear three-wave interactions control the shape of the frequency distribution of the dissipation rate. In the wake of the storm, the viscosity values predicted by the inverse modeling converge toward measured values characteristic for gelled mud in a trend that is consistent with a fluid mud entering dewatering and consolidation stages. C1 [Sheremet, A.; Su, S-F.] Univ Florida, Gainesville, FL 32611 USA. [Allison, M. A.] Univ Texas Austin, Inst Geophys, Austin, TX 78758 USA. [Holland, K. T.] USN, Seafloor Sci Branch, Res Lab, Stennis Space Ctr, MS 39529 USA. [Jaramillo, S.] Univ Hawaii Manoa, Sch Ocean & Earth Sci & Technol, Honolulu, HI 96822 USA. RP Sheremet, A (reprint author), Univ Florida, 365 Weil Hall, Gainesville, FL 32611 USA. EM alex@coastal.ufl.edu; sjara@hawaii.edu; ssf@ufl.edu; mallison@mail.utexas.edu; tholland@nrlssc.navy.mil RI Allison, Mead/A-7208-2010; Holland, K. Todd/A-7673-2011; Jaramillo, Sergio/K-3081-2012 OI Holland, K. Todd/0000-0002-4601-6097; FU Office of Naval Research [N00014-07-1-0448, N00014-08-1-0598] FX This work is supported by the Office of Naval Research awards N00014-07-1-0448 and N00014-08-1-0598. Data was collected with the support of Coastal Studies Institute, Louisiana State University. We are grateful to A. Mehta for suggestions and advice on mud modeling and for providing data to characterize the Atchafalaya mud, to Erick Rogers for discussions on the SWAN-based inverse modeling approach, and to the anonymous reviewers, whose advice helped improve this manuscript. NR 42 TC 21 Z9 21 U1 1 U2 8 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 0148-0227 J9 J GEOPHYS RES-OCEANS JI J. Geophys. Res.-Oceans PD JUN 15 PY 2011 VL 116 AR C06005 DI 10.1029/2010JC006644 PG 14 WC Oceanography SC Oceanography GA 780AU UT WOS:000291824300002 ER PT J AU Pruessner, MW Khurgin, JB Stievater, TH Rabinovich, WS Bass, R Boos, JB Urick, VJ AF Pruessner, Marcel W. Khurgin, Jacob B. Stievater, Todd H. Rabinovich, William S. Bass, Robert Boos, J. Brad Urick, Vincent J. TI Demonstration of a mode-conversion cavity add-drop filter SO OPTICS LETTERS LA English DT Article ID RESONATORS AB We experimentally demonstrate a new type of add-drop filter incorporating an asymmetric Y-branch waveguide coupler and a shifted-grating mode-conversion cavity. The device relies on mode separation in the asymmetric Y-branch and wavelength-selective mode conversion upon reflection from the shifted-grating cavity. Add-drop functionality is demonstrated in a three-port integrated silicon-on-insulator device. (C) 2011 Optical Society of America C1 [Pruessner, Marcel W.; Stievater, Todd H.; Rabinovich, William S.; Bass, Robert; Boos, J. Brad; Urick, Vincent J.] USN, Res Lab, Washington, DC 20375 USA. [Khurgin, Jacob B.] Johns Hopkins Univ, Baltimore, MD 21218 USA. RP Pruessner, MW (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM marcelwp@ccs.nrl.navy.mil RI khurgin, Jacob/A-3278-2010 FU Office of Naval Research (ONR) FX M. W. Pruessner thanks the NRL Nanoscience Institute staff for fabrication assistance. The authors acknowledge the support of the Office of Naval Research (ONR). NR 11 TC 13 Z9 13 U1 0 U2 6 PU OPTICAL SOC AMER PI WASHINGTON PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA SN 0146-9592 J9 OPT LETT JI Opt. Lett. PD JUN 15 PY 2011 VL 36 IS 12 BP 2230 EP 2232 PG 3 WC Optics SC Optics GA 778RI UT WOS:000291722100019 PM 21685976 ER PT J AU Kutana, A Erwin, SC AF Kutana, Alex Erwin, Steven C. TI PbSe nanocrystals remain intrinsic after surface adsorption of hydrazine SO PHYSICAL REVIEW B LA English DT Article ID ORIENTED ATTACHMENT; QUANTUM DOTS; NANOWIRES; GROWTH; FILMS; ALIGNMENT; SOLIDS; POLAR AB Recent experiments have shown a dramatic increase in the conductivity of PbSe nanocrystalline films after hydrazine treatment, suggesting that hydrazine may create free carriers in PbSe nanocrystals. Here, we study the effect of hydrazine adsorption on the electronic structure of PbSe nanocrystals using density functional theory. The physisorption of the intact hydrazine molecule and its dissociative chemisorption on different surfaces of PbSe are considered. Despite experimental indications of the n-type doping by hydrazine in PbSe, no theoretical evidence of the effect is found. Instead, PbSe is predicted to remain an intrinsic semiconductor after surface doping by hydrazine, and become a p-type semiconductor after doping by the hydrazine fragments. We attribute the discrepancy between experiment and theory to indirect effects, such as self-doping by excess surface atoms due to selective surface etching. C1 [Kutana, Alex; Erwin, Steven C.] USN, Res Lab, Ctr Computat Mat Sci, Washington, DC 20375 USA. RP Kutana, A (reprint author), USN, Res Lab, Ctr Computat Mat Sci, Washington, DC 20375 USA. FU Naval Research Laboratory FX This work was performed under the ASEE program at the Naval Research Laboratory. Computations were performed at the DoD Shared Resource Center at ARSC. NR 31 TC 12 Z9 12 U1 0 U2 21 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1098-0121 J9 PHYS REV B JI Phys. Rev. B PD JUN 15 PY 2011 VL 83 IS 23 AR 235419 DI 10.1103/PhysRevB.83.235419 PG 4 WC Physics, Condensed Matter SC Physics GA 777VZ UT WOS:000291654500007 ER PT J AU Shen, YC Hsia, RY AF Shen, Yu-Chu Hsia, Renee Y. TI Association Between Ambulance Diversion and Survival Among Patients With Acute Myocardial Infarction SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article ID HOSPITAL CARDIAC-ARREST; LENGTH-OF-STAY; EMERGENCY-DEPARTMENTS; MORTALITY; IMPACT; DELAYS; TIMES; CARE AB Context Ambulance diversion, a practice in which emergency departments (EDs) are temporarily closed to ambulance traffic, might be problematic for patients experiencing time-sensitive conditions, such as acute myocardial infarction (AMI). However, there is little empirical evidence to show whether diversion is associated with worse patient outcomes. Objective To analyze whether temporary ED closure on the day a patient experiences AMI, as measured by ambulance diversion hours of the nearest ED, is associated with increased mortality rates among patients with AMI. Design, Study, and Participants A case-crossover design of 13 860 Medicare patients with AMI from 508 zip codes within 4 California counties (Los Angeles, San Francisco, San Mateo, and Santa Clara) whose admission date was between 2000 and 2005. Data included 100% Medicare claims data that covered admissions between 2000 and 2005, linked with date of death until 2006, and daily ambulance diversion logs from the same 4 counties. Among the hospital universe, 149 EDs were identified as the nearest ED to these patients. Main Outcome Measures The percentage of patients with AMI who died within 7 days, 30 days, 90 days, 9 months, and 1 year from admission (when their nearest ED was not on diversion and when that same ED was exposed to <6, 6 to <12, and >= 12 hours of diversion out of 24 hours on the day of admission). Results Between 2000 and 2006, the mean (SD) daily diversion duration was 7.9 (6.1) hours. Based on analysis of 11 625 patients admitted to the ED between 2000 and 2005, and whose nearest ED had at least 3 diversion exposure levels (3541, 3357, 2667, and 2060 patients for no exposure, exposure to <6, 6 to <12, and >= 12 hours of diversion, respectively), there were no statistically significant differences in mortality rates between no diversion and exposure to less than 12 hours of diversion. Exposure to 12 or more hours of diversion was associated with higher 30-day mortality vs no diversion status (unadjusted mortality rate, 392 patients [19%] vs 545 patients [15%]; regression adjusted difference, 3.24 percentage points; 95% confidence interval [CI], 0.60-5.88); higher 90-day mortality (537 patients [26%] vs 762 patients [22%]; 2.89 percentage points; 95% CI, 0.13-5.64); higher 9-month mortality (680 patients [33%] vs 980 patients [28%]; 2.93 percentage points; 95% CI, 0.15-5.71); and higher 1-year mortality (731 patients [35%] vs 1034 patients [29%]; 3.04 percentage points; 95% CI, 0.33-5.75). Conclusion Among Medicare patients with AMI in 4 populous California counties, exposure to at least 12 hours of diversion by the nearest ED was associated with increased 30-day, 90-day, 9-month, and 1-year mortality. JAMA. 2011;305(23):2440-2447 www.jama.com C1 [Shen, Yu-Chu] USN, Postgrad Sch, Grad Sch Business & Publ Policy, Monterey, CA 93943 USA. [Shen, Yu-Chu] Natl Bur Econ Res, Cambridge, MA 02138 USA. [Hsia, Renee Y.] Univ Calif San Francisco, San Francisco Gen Hosp, Dept Emergency Med, San Francisco, CA USA. RP Shen, YC (reprint author), USN, Postgrad Sch, Grad Sch Business & Publ Policy, 555 Dyer Rd,Code GB, Monterey, CA 93943 USA. EM yshen@nps.edu FU Robert Wood Johnson Foundation's Changes in Health Care Financing and Organization initiative [63974]; National Institutes of Health/National Center for Research Resources, University of California, San Francisco Clinical and Translational Science [KL2 RR024130] FX This work was supported by grant 63974 from the Robert Wood Johnson Foundation's Changes in Health Care Financing and Organization initiative (Dr Shen), grant KL2 RR024130 from the National Institutes of Health/National Center for Research Resources, University of California, San Francisco Clinical and Translational Science (Dr Hsia), and the Robert Wood Johnson Foundation Physician Faculty Scholars (Dr Hsia). NR 41 TC 37 Z9 37 U1 0 U2 1 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60654-0946 USA SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD JUN 15 PY 2011 VL 305 IS 23 BP 2440 EP 2447 DI 10.1001/jama.2011.811 PG 8 WC Medicine, General & Internal SC General & Internal Medicine GA 777EB UT WOS:000291597300024 PM 21666277 ER PT J AU Tumialan, LM Gluf, WM AF Tumialan, Luis. M. Gluf, Wayne M. TI Progressive Vertebral Body Osteolysis After Cervical Disc Arthroplasty SO SPINE LA English DT Article DE arthroplasty; cervical; complication; osteolysis; ProDisc C ID METAL SENSITIVITY; PRODISC-C; ORTHOPEDIC IMPLANTS; REPLACEMENT AB Study Design. Case report. Objective. To review the management of a patient with progressive osteolysis of the vertebral body after undergoing cervical arthroplasty for management of a refractory radiculopathy. Summary of Background Data. Since the Food and Drug Administration's (FDA) approval of cervical arthroplasty devices in 2007, many surgeons have incorporated this technology into clinical practice. As arthroplasty becomes more widespread, complications unique to this technology are inevitable. To date, only a limited number of complications have been reported in the literature suggesting the safety of this device. To the authors' knowledge, this report represents the first complication of osteolysis from a keel based arthroplasty device. Methods. A 30-year-old man underwent an uneventful C5-C6 total disc arthroplasty with initial benefit. Progressively worsening neck pain prompted repeat imaging at 9 and 15 months, which showed a progressive osteolytic process in the vicinity of the keel of the superior alloy endplate. This necessitated exploration of the surgical site, explantation of the implant and conversion of the disc arthroplasty to an arthrodesis. Results. Examination of the osteolytic area did not reveal any gross abnormalities. Testing of the device by the manufacturer did not reveal any defects. A comprehensive infectious workup was negative. The osteolytic process halted after the explantation of the device. A bony arthrodesis was achieved at 6 months and the patient remains symptom free 29 months after the initial procedure and 14 months after the revision. Conclusion. This report illustrates an exceptional case of a progressive osteolysis with a keel based arthroplasty device. An immune mediated osteolytic process appears to be a plausible explanation for the clinical symptoms and radiographic progression seen in this case. Given the years of use of the ProDisc-C since its FDA approval in 2007, complications with this device are rare. This represents the first reported case of osteolysis from such an implant. C1 [Tumialan, Luis. M.] St Josephs Hosp, Barrow Neurol Inst, Div Neurol Surg, Phoenix, AZ 85013 USA. [Gluf, Wayne M.] USN, San Diego Med Ctr, Dept Neurosurg, San Diego, CA 92152 USA. RP Tumialan, LM (reprint author), St Josephs Hosp, Barrow Neurol Inst, Div Neurol Surg, 2910 N 3rd Ave, Phoenix, AZ 85013 USA. EM luis.tumialan@bnaneuro.net NR 19 TC 11 Z9 11 U1 0 U2 1 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0362-2436 J9 SPINE JI SPINE PD JUN 15 PY 2011 VL 36 IS 14 BP E973 EP E978 DI 10.1097/BRS.0b013e3181fd863b PG 6 WC Clinical Neurology; Orthopedics SC Neurosciences & Neurology; Orthopedics GA 772PC UT WOS:000291245100011 PM 21289567 ER PT J AU Crum-Cianflone, NF Wilkins, K Lee, AW Grosso, A Landrum, ML Weintrob, A Ganesan, A Maguire, J Klopfer, S Brandt, C Bradley, WP Wallace, MR Agan, BK AF Crum-Cianflone, Nancy F. Wilkins, Kenneth Lee, Andrew W. Grosso, Anthony Landrum, Michael L. Weintrob, Amy Ganesan, Anuradha Maguire, Jason Klopfer, Stephanie Brandt, Carolyn Bradley, William P. Wallace, Mark R. Agan, Brian K. CA Infect Dis Clinical Res Program HI TI Long-term Durability of Immune Responses After Hepatitis A Vaccination Among HIV-Infected Adults SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID HUMAN-IMMUNODEFICIENCY-VIRUS; ACTIVE ANTIRETROVIRAL THERAPY; ANTIBODY-RESPONSES; HOMOSEXUAL-MEN; IMMUNOGENICITY; INDIVIDUALS; SAFETY; PROTECTION; VAQTA(R); CHILDREN AB Methods. We retrospectively studied HIV-infected adults who had received 2 doses of HAV vaccine. We analyzed blood specimens taken at 1 year, 3 years, and, when available, 6-10 years postvaccination. HAV immunoglobulin G (IgG) values of >= 10 mIU/mL were considered seropositive. Results. We evaluated specimens from 130 HIV-infected adults with a median age of 35 years and a median CD4 cell count of 461 cells/mm(3) at or before time of vaccination. Of these, 49% had an HIV RNA load < 1000 copies/mL. Initial vaccine responses were achieved in 89% of HIV-infected adults (95% confidence interval [CI], 83%-94%), compared with 100% (95% CI, 99%-100%) of historical HIV-uninfected adults. Among initial HIV-infected responders with available specimens, 90% (104 of 116; 95% CI, 83%-95%) remained seropositive at 3 years and 85% (63 of 74; 95% CI, 75%-92%) at 6-10 years. Geometric mean concentrations (GMCs) among HIV-infected adults were 154, 111, and 64 mIU/mL at 1, 3, and 6-10 years, respectively, compared with 1734, 687, and 684 mIU/mL among HIV-uninfected persons. Higher GMCs over time among HIV-infected adults were associated with lower log(10) HIV RNA levels (beta = -.12, P = .04). Conclusions. Most adults with well-controlled HIV infections had durable seropositive responses up to 6-10 years after HAV vaccination. Suppressed HIV RNA levels are associated with durable HAV responses. C1 [Crum-Cianflone, Nancy F.; Wilkins, Kenneth; Landrum, Michael L.; Weintrob, Amy; Ganesan, Anuradha; Maguire, Jason; Brandt, Carolyn; Bradley, William P.; Agan, Brian K.] Uniformed Serv Univ Hlth Sci, Infect Dis Clin Res Program, Bethesda, MD 20814 USA. [Crum-Cianflone, Nancy F.; Brandt, Carolyn] USN, Infect Dis Clin, San Diego Med Ctr, San Diego, CA 92134 USA. [Lee, Andrew W.; Grosso, Anthony; Klopfer, Stephanie] Merck Res Labs, N Wales, PA USA. [Landrum, Michael L.] San Antonio Mil Med Ctr, Infect Dis Serv, San Antonio, TX USA. [Weintrob, Amy] Walter Reed Army Med Ctr, Infect Dis Clin, Washington, DC 20307 USA. [Ganesan, Anuradha] Natl Naval Med Ctr, Infect Dis Clin, Bethesda, MD USA. [Maguire, Jason] Naval Med Ctr Portsmouth, Infect Dis Clin, Portsmouth, VA USA. [Wallace, Mark R.] Orlando Reg Med Clin, Infect Dis Clin, Orlando, FL USA. RP Crum-Cianflone, NF (reprint author), USN, Clin Invest Dept KCA, San Diego Med Ctr, 34800 Bob Wilson Dr,Ste 5, San Diego, CA 92134 USA. EM nancy.crum@med.navy.mil OI Polis, Michael/0000-0002-9151-2268; Agan, Brian/0000-0002-5114-1669 FU Department of Defense through the Uniformed Services University of the Health Sciences [IDCRP-000-11]; National Institute of Allergy and Infectious Diseases, National Institutes of Health [Y1-AI-5072] FX This work was supported by the Infectious Disease Clinical Research Program, a Department of Defense program executed through the Uniformed Services University of the Health Sciences (IDCRP-000-11); and the National Institute of Allergy and Infectious Diseases, National Institutes of Health (Inter-Agency Agreement Y1-AI-5072). NR 43 TC 24 Z9 25 U1 0 U2 2 PU OXFORD UNIV PRESS INC PI CARY PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA SN 1537-6613 J9 J INFECT DIS JI J. Infect. Dis. PD JUN 15 PY 2011 VL 203 IS 12 BP 1815 EP 1823 DI 10.1093/infdis/jir180 PG 9 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA 770BO UT WOS:000291062200016 PM 21606540 ER PT J AU Hoang, K Johannes, M AF Hoang, Khang Johannes, Michelle TI Tailoring Native Defects in LiFePO4: Insights from First-Principles Calculations SO CHEMISTRY OF MATERIALS LA English DT Article DE lithium iron phosphate; defects; first-principles; polaron; ionic conduction ID POSITIVE-ELECTRODE MATERIALS; DENSITY-FUNCTIONAL THEORY; TOTAL-ENERGY CALCULATIONS; AUGMENTED-WAVE METHOD; LITHIUM-ION; BASIS-SET; LIMPO4 M; CONDUCTIVITY; TRANSPORT; BATTERIES AB We report first-principles density-functional theory studies of native point defects and defect complexes in olivine-type LiFePO4, a promising candidate for rechargeable Li-ion battery electrodes. The defects are characterized by their formation energies, which are calculated within the GGA+U framework. We find that native point defects are charged, and each defect is stable in one charge state only. Removing electrons from the stable defects always generates defect complexes containing small hole polarons. Defect formation energies, hence concentrations, and defect energy landscapes are all sensitive to the choice of atomic chemical potentials, which represent experimental conditions. One can, therefore, suppress or enhance certain native defects in LiFePO4 via tuning the synthesis conditions. On the basis of our results, we provide insights on how to obtain samples in experiments with tailored defect concentrations for targeted applications. We also discuss the mechanisms for ionic and electronic conduction in LiFePO4 and suggest strategies for enhancing the electrical conductivity. C1 [Hoang, Khang; Johannes, Michelle] USN, Res Lab, Ctr Computat Mat Sci, Washington, DC 20375 USA. [Hoang, Khang] George Mason Univ, Sch Phys Astron & Computat Sci, Fairfax, VA 22030 USA. RP Johannes, M (reprint author), USN, Res Lab, Ctr Computat Mat Sci, Washington, DC 20375 USA. EM michelle.johannes@nrl.navy.mil RI Hoang, Khang/C-2879-2008 OI Hoang, Khang/0000-0003-1889-0745 FU Naval Research Laboratory [NRL-N00173-08-G001]; Office of Naval Research FX We acknowledge helpful discussions with S. C. Erwin and J. Allen, and the use of computing facilities at the DoD HPC Centers. K.H. was supported by the Naval Research Laboratory through Grant No. NRL-N00173-08-G001, and M.J. was supported by the Office of Naval Research. NR 54 TC 68 Z9 68 U1 2 U2 63 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0897-4756 J9 CHEM MATER JI Chem. Mat. PD JUN 14 PY 2011 VL 23 IS 11 BP 3003 EP 3013 DI 10.1021/cm200725j PG 11 WC Chemistry, Physical; Materials Science, Multidisciplinary SC Chemistry; Materials Science GA 773GD UT WOS:000291294100042 ER PT J AU Pecora, LM Lee, H Wu, DH Antonsen, T Lee, MJ Ott, E AF Pecora, Louis M. Lee, Hoshik Wu, Dong-Ho Antonsen, Thomas Lee, Ming-Jer Ott, Edward TI Chaos regularization of quantum tunneling rates SO PHYSICAL REVIEW E LA English DT Article ID REGIME; MATRIX; STATES AB Quantum tunneling rates through a barrier separating two-dimensional, symmetric, double-well potentials are shown to depend on the classical dynamics of the billiard trajectories in each well and, hence, on the shape of the wells. For shapes that lead to regular (integrable) classical dynamics the tunneling rates fluctuate greatly with eigenenergies of the states sometimes by over two orders of magnitude. Contrarily, shapes that lead to completely chaotic trajectories lead to tunneling rates whose fluctuations are greatly reduced, a phenomenon we call regularization of tunneling rates. We show that a random-plane-wave theory of tunneling accounts for the mean tunneling rates and the small fluctuation variances for the chaotic systems. C1 [Pecora, Louis M.; Wu, Dong-Ho] USN, Res Lab, Washington, DC 20375 USA. [Lee, Hoshik] Coll William & Mary, Dept Phys, Williamsburg, VA 23187 USA. [Antonsen, Thomas; Lee, Ming-Jer; Ott, Edward] Univ Maryland, Dept Phys, College Pk, MD 20742 USA. [Antonsen, Thomas; Lee, Ming-Jer; Ott, Edward] Univ Maryland, Dept Elect Engn, College Pk, MD 20742 USA. RP Pecora, LM (reprint author), USN, Res Lab, Washington, DC 20375 USA. RI O, E/F-1630-2015 FU ONR [N00014-07-1-0734] FX This work was partly supported by ONR Grant No. N00014-07-1-0734 NR 21 TC 15 Z9 15 U1 0 U2 4 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1539-3755 EI 1550-2376 J9 PHYS REV E JI Phys. Rev. E PD JUN 13 PY 2011 VL 83 IS 6 AR 065201 DI 10.1103/PhysRevE.83.065201 PN 2 PG 4 WC Physics, Fluids & Plasmas; Physics, Mathematical SC Physics GA 778KM UT WOS:000291702600001 PM 21797430 ER PT J AU Hartley, DJ Janssens, RVF Riedinger, LL Riley, MA Wang, X Aguilar, A Carpenter, MP Chiara, CJ Chowdhury, P Darby, IG Garg, U Ijaz, QA Kondev, FG Lakshmi, S Lauritsen, T Ludington, A Ma, WC McCutchan, EA Mukhopadhyay, S Pifer, R Seyfried, EP Shirwadkar, U Stefanescu, I Tandel, SK Vanhoy, JR Zhu, S Frauendorf, S AF Hartley, D. J. Janssens, R. V. F. Riedinger, L. L. Riley, M. A. Wang, X. Aguilar, A. Carpenter, M. P. Chiara, C. J. Chowdhury, P. Darby, I. G. Garg, U. Ijaz, Q. A. Kondev, F. G. Lakshmi, S. Lauritsen, T. Ludington, A. Ma, W. C. McCutchan, E. A. Mukhopadhyay, S. Pifer, R. Seyfried, E. P. Shirwadkar, U. Stefanescu, I. Tandel, S. K. Vanhoy, J. R. Zhu, S. Frauendorf, S. TI Rotational structures and the wobbling mode in Ta-167 SO PHYSICAL REVIEW C LA English DT Article ID HIGH-SPIN STATES; COINCIDENCE DATA; NUCLEI; EXCITATIONS; DEFORMATIONS; MOTION; LU-165; PHONON; W-167 AB Excited states in the neutron-deficient nucleus Ta-167 were studied through the Sn-120(V-51,4n) reaction. Twelve rotational bands have been observed and the relative excitation energy of each sequence is now known owing to the multiple interband connections. Several quasineutron alignments were observed that aided in the quasiparticle assignments of these bands. The resulting interpretation is in line with observations in neighboring nuclei. Trends in the wobbling phonon energy seen in Lu-161,Lu-163,Lu-165,Lu-167 and Ta-167 are also discussed and particle-rotor model calculations (assuming constant moments of inertia) are found to be inconsistent with the experimental data. C1 [Hartley, D. J.; Ludington, A.; Pifer, R.; Seyfried, E. P.; Vanhoy, J. R.] USN Acad, Dept Phys, Annapolis, MD 21402 USA. [Janssens, R. V. F.; Carpenter, M. P.; Chiara, C. J.; Lauritsen, T.; McCutchan, E. A.; Stefanescu, I.; Zhu, S.] Argonne Natl Lab, Div Phys, Argonne, IL 60439 USA. [Riedinger, L. L.; Darby, I. G.] Univ Tennessee, Dept Phys & Astron, Knoxville, TN 37996 USA. [Riley, M. A.; Wang, X.; Aguilar, A.] Florida State Univ, Dept Phys, Tallahassee, FL 32306 USA. [Chiara, C. J.; Kondev, F. G.] Argonne Natl Lab, Nucl Engn Div, Argonne, IL 60439 USA. [Chiara, C. J.; Stefanescu, I.] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA. [Chowdhury, P.; Lakshmi, S.; Shirwadkar, U.; Tandel, S. K.] Univ Massachusetts, Dept Phys, Lowell, MA 01854 USA. [Garg, U.; Mukhopadhyay, S.; Frauendorf, S.] Univ Notre Dame, Dept Phys, Notre Dame, IN 46556 USA. [Ijaz, Q. A.; Ma, W. C.] Mississippi State Univ, Dept Phys, Mississippi State, MS 39762 USA. RP Hartley, DJ (reprint author), USN Acad, Dept Phys, Annapolis, MD 21402 USA. RI Soundara Pandian, Lakshmi/C-8107-2013; Carpenter, Michael/E-4287-2015 OI Soundara Pandian, Lakshmi/0000-0003-3099-1039; Carpenter, Michael/0000-0002-3237-5734 FU National Science Foundation [PHY-0854815, PHY-0754674, PHY07-58100]; US Department of Energy, Office of Nuclear Physics [DE-AC02-06CH11357, DE-FG02-94ER40848, DE-FG02-94ER40834, DE-FG02-95ER40939, DE-FG02-96ER40983] FX The authors thank the ANL operations staff at Gammasphere and gratefully acknowledge the efforts of J. P. Greene for target preparation. We thank D. C. Radford and H. Q. Jin for their software support. This work is funded by the National Science Foundation under Grants No. PHY-0854815 (USNA), No. PHY-0754674 (FSU), and No. PHY07-58100 (ND), as well as by the US Department of Energy, Office of Nuclear Physics, under Contract No. DE-AC02-06CH11357 (ANL), and Grants No. DE-FG02-94ER40848 (UML), No. DE-FG02-94ER40834 (UM), No. DE-FG02-95ER40939 (MSU), and No. DE-FG02-96ER40983 (UT). NR 38 TC 8 Z9 9 U1 2 U2 6 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0556-2813 J9 PHYS REV C JI Phys. Rev. C PD JUN 13 PY 2011 VL 83 IS 6 AR 064307 DI 10.1103/PhysRevC.83.064307 PG 19 WC Physics, Nuclear SC Physics GA 777GX UT WOS:000291605000001 ER PT J AU Curtin, AE Fuhrer, MS Tedesco, JL Myers-Ward, RL Eddy, CR Gaskill, DK AF Curtin, A. E. Fuhrer, M. S. Tedesco, J. L. Myers-Ward, R. L. Eddy, C. R., Jr. Gaskill, D. K. TI Kelvin probe microscopy and electronic transport in graphene on SiC(0001) in the minimum conductivity regime SO APPLIED PHYSICS LETTERS LA English DT Article ID EPITAXIAL GRAPHENE; SILICON-CARBIDE; WAFER-SCALE AB Ambient-environment Kelvin probe microscopy of many (10 mu m)(2) areas of single-layer graphene on SiC(0001) shows area-to-area rms surface potential variation of 12 meV. Electronic transport data are consistent with the minimum conductivity regime. Together the data indicate a highly uniform carrier concentration with a small magnitude (<10(12) cm(-2)). We conclude that the previously reported large spread in carrier densities from Hall measurements on similar samples is an artifact of electron-hole puddling in the minimum conductivity regime. (C) 2011 American Institute of Physics. [doi:10.1063/1.3595360] C1 [Curtin, A. E.; Fuhrer, M. S.] Univ Maryland, Ctr Nanophys & Adv Mat, College Pk, MD 20742 USA. [Tedesco, J. L.; Myers-Ward, R. L.; Eddy, C. R., Jr.; Gaskill, D. K.] USN, Res Lab, Washington, DC 20375 USA. RP Curtin, AE (reprint author), Univ Maryland, Ctr Nanophys & Adv Mat, College Pk, MD 20742 USA. EM mfuhrer@physics.umd.edu RI Fuhrer, Michael/E-7634-2010 OI Fuhrer, Michael/0000-0001-6183-2773 FU ASEE; Office of Naval Research; University of Maryland NSF-MRSEC and MRSEC shared facilities [DMR 05-20741] FX J.L.T. is grateful to the ASEE for postdoctoral fellowship support. Work at NRL was supported by the Office of Naval Research. A. E. C. and M. S. F. acknowledge support from the University of Maryland NSF-MRSEC and MRSEC shared facilities under Grant No. DMR 05-20741. NR 22 TC 22 Z9 22 U1 2 U2 34 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD JUN 13 PY 2011 VL 98 IS 24 AR 243111 DI 10.1063/1.3595360 PG 3 WC Physics, Applied SC Physics GA 779SZ UT WOS:000291803600078 ER PT J AU Gallo, EM Chen, GN Currie, M McGuckin, T Prete, P Lovergine, N Nabet, B Spanier, JE AF Gallo, Eric M. Chen, Guannan Currie, Marc McGuckin, Terrence Prete, Paola Lovergine, Nico Nabet, Bahram Spanier, Jonathan E. TI Picosecond response times in GaAs/AlGaAs core/shell nanowire-based photodetectors SO APPLIED PHYSICS LETTERS LA English DT Article ID HETEROSTRUCTURES AB High-speed metal-semiconductor-metal (MSM) photodetectors based on Schottky-contacted core/shell GaAs/AlGaAs and bare GaAs nanowires were fabricated and characterized. The measured core/shell temporal response has a similar to 10 ps full-width at half-maximum and an estimated corrected value less than 5 ps. The bare GaAs devices exhibit a slower response (similar to 35 ps) along with a slow decaying persistent photocurrent (similar to 80 s). The core/shell devices exhibit significantly improved dc and high-speed performance over bare nanowires and comparable performance to planar MSM photodetectors. The picosecond temporal response, coupled with picoampere dark current, demonstrate the potential for core/shell nanowires in high-speed imaging arrays and on-chip optical interconnects. (C) 2011 American Institute of Physics. [doi:10.1063/1.3600061] C1 [Gallo, Eric M.; Chen, Guannan; McGuckin, Terrence; Spanier, Jonathan E.] Drexel Univ, Dept Mat Sci & Engn, Philadelphia, PA 19104 USA. [Currie, Marc] USN, Res Lab, Div Opt Sci, Washington, DC 20375 USA. [Prete, Paola] Consiglio Nazl Ric CNR, Ist Microelettron Microsistemi IMM, I-73100 Lecce, Italy. [Lovergine, Nico] Univ Salento, Dept Innovat Engn, I-73100 Lecce, Italy. [Nabet, Bahram] Drexel Univ, Dept Elect & Comp Engn, Philadelphia, PA 19104 USA. RP Gallo, EM (reprint author), Drexel Univ, Dept Mat Sci & Engn, Philadelphia, PA 19104 USA. EM spanier@drexel.edu RI Chen, Guannan/F-6440-2010; Lovergine, Nico/N-5324-2015; PRETE, PAOLA/C-1717-2016; OI Chen, Guannan/0000-0003-1868-4327; Lovergine, Nico/0000-0003-0190-4899; PRETE, PAOLA/0000-0002-4948-4718; Spanier, Jonathan/0000-0002-3096-2644 FU NSF [DMR-0907381, DGE-0538476]; U.S. Army Research Office [W911NF-08-1-0067]; Office of Naval Research FX This work at Drexel was supported by the NSF (Grant No. DMR-0907381) and in part by the U.S. Army Research Office (Grant No. W911NF-08-1-0067). E. M. G. was supported in part by the NSF GK-12 Graduate Fellowship (Grant No. DGE-0538476) and M. C. was supported by the Office of Naval Research. The authors would also like to thank Michelle Sipics for assistance in manuscript preparation. NR 17 TC 47 Z9 49 U1 4 U2 41 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD JUN 13 PY 2011 VL 98 IS 24 AR 241113 DI 10.1063/1.3600061 PG 3 WC Physics, Applied SC Physics GA 779SZ UT WOS:000291803600013 ER PT J AU Kong, BD Semenov, YG Krowne, CM Kim, KW AF Kong, B. D. Semenov, Y. G. Krowne, C. M. Kim, K. W. TI Unusual magnetoresistance in a topological insulator with a single ferromagnetic barrier SO APPLIED PHYSICS LETTERS LA English DT Article ID SURFACE AB Tunneling surface current through a thin ferromagnetic barrier on a three-dimensional topological insulator is shown to possess an extraordinary response to the orientation of barrier magnetization. In contrast to conventional magnetoresistance devices that are sensitive to the relative alignment of two magnetic layers, a drastic change in the transmission current is achieved by a single layer when its magnetization rotates by 90 degrees. Numerical estimations predict a giant magnetoresistance as large as 800% at room temperature with the proximate exchange energy of 40 meV at the barrier interface. When coupled with electrical control of magnetization direction, this phenomenon may be used to enhance the gating function with potentially sharp turn-on/off for low power applications. (C) 2011 American Institute of Physics. [doi:10.1063/1.3600330] C1 [Kong, B. D.; Semenov, Y. G.; Kim, K. W.] N Carolina State Univ, Dept Elect & Comp Engn, Raleigh, NC 27695 USA. [Krowne, C. M.] USN, Div Elect Sci & Technol, Res Lab, Washington, DC 20375 USA. RP Kong, BD (reprint author), N Carolina State Univ, Dept Elect & Comp Engn, Raleigh, NC 27695 USA. EM kwk@ncsu.edu RI KONG, BYOUNG DON/A-2186-2012 OI KONG, BYOUNG DON/0000-0003-4072-4399 FU SRC Focus Center on Functional Engineered Nano Architectonics (FENA); U.S. Army Research Office FX This work was supported, in part, by the SRC Focus Center on Functional Engineered Nano Architectonics (FENA) and the U.S. Army Research Office. NR 18 TC 42 Z9 42 U1 8 U2 36 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD JUN 13 PY 2011 VL 98 IS 24 AR 243112 DI 10.1063/1.3600330 PG 3 WC Physics, Applied SC Physics GA 779SZ UT WOS:000291803600079 ER PT J AU Hindsley, RB Armstrong, JT Schmitt, HR Andrews, JR Restaino, SR Wilcox, CC Vrba, FJ Benson, JA DiVittorio, ME Hutter, DJ Shankland, PD Gregory, SA AF Hindsley, Robert B. Armstrong, J. Thomas Schmitt, Henrique R. Andrews, Jonathan R. Restaino, Sergio R. Wilcox, Christopher C. Vrba, Frederick J. Benson, James A. DiVittorio, Michael E. Hutter, Donald J. Shankland, Paul D. Gregory, Steven A. TI Navy Prototype Optical Interferometer observations of geosynchronous satellites SO APPLIED OPTICS LA English DT Article AB Using a 15.9 m baseline at the Navy Prototype Optical Interferometer (NPOI), we have successfully detected interferometric fringes in observations of the geosynchronous satellite (geosat) DirecTV-9S while it glinted on two nights in March 2009. The fringe visibilities can be fitted by a model consisting of two components, one resolved (greater than or similar to 3.7 m) and one unresolved (similar to 1.1 m). Both the length of the glint and the specular albedos are consistent with the notion that the glinting surfaces are not completely flat and scatter reflected sunlight into an opening angle of roughly 15 degrees. Enhancements to the NPOI that would improve geosat observations include adding an infrared capability, which could extend the glint season, and adding larger, adaptive-optics equipped telescopes. Future work may test the feasibility of observing geosats with aperture-masked large telescopes and of developing an array of six to nine elements. (C) 2011 Optical Society of America C1 [Hindsley, Robert B.; Armstrong, J. Thomas; Schmitt, Henrique R.] USN, Res Lab, Remote Sensing Div, Washington, DC 20375 USA. [Schmitt, Henrique R.] Computat Phys Inc, Springfield, VA 22151 USA. [Andrews, Jonathan R.; Restaino, Sergio R.; Wilcox, Christopher C.] USN, Res Lab, Remote Sensing Div, Albuquerque, NM 87117 USA. [Vrba, Frederick J.; Benson, James A.; DiVittorio, Michael E.; Hutter, Donald J.; Shankland, Paul D.] US Naval Observ, Flagstaff Stn, Flagstaff, AZ 86001 USA. [Gregory, Steven A.] Boeing LTS, Albuquerque, NM 87117 USA. RP Hindsley, RB (reprint author), USN, Res Lab, Remote Sensing Div, 4555 Overlook Ave NW, Washington, DC 20375 USA. EM hindsley@nrl.navy.mil NR 12 TC 11 Z9 11 U1 0 U2 2 PU OPTICAL SOC AMER PI WASHINGTON PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA SN 1559-128X EI 2155-3165 J9 APPL OPTICS JI Appl. Optics PD JUN 10 PY 2011 VL 50 IS 17 BP 2692 EP 2698 DI 10.1364/AO.50.002692 PG 7 WC Optics SC Optics GA 780QG UT WOS:000291872800025 PM 21673773 ER PT J AU Agakishiev, H Aggarwal, MM Ahammed, Z Alakhverdyants, AV Alekseev, I Alford, J Anderson, BD Anson, CD Arkhipkin, D Averichev, GS Balewski, J Beavis, DR Behera, NK Bellwied, R Betancourt, MJ Betts, RR Bhasin, A Bhati, AK Bichsel, H Bielcik, J Bielcikova, J Biritz, B Bland, LC Bordyuzhin, IG Borowski, W Bouchet, J Braidot, E Brandin, AV Bridgeman, A Brovko, SG Bruna, E Bueltmann, S Bunzarov, I Burton, TP Cai, XZ Caines, H Sanchez, MCD Cebra, D Cendejas, R Cervantes, MC Chajecki, Z Chaloupka, P Chattopadhyay, S Chen, HF Chen, JH Chen, JY Chen, L Cheng, J Cherney, M Chikanian, A Choi, KE Christie, W Chung, P Codrington, MJM Corliss, R Cramer, JG Crawford, HJ Dash, S Leyva, AD De Silva, LC Debbe, RR Dedovich, TG Derevschikov, AA de Souza, RD Didenko, L Djawotho, P Dogra, SM Dong, X Drachenberg, JL Draper, JE Dunlop, JC Efimov, LG Elnimr, M Engelage, J Eppley, G Estienne, M Eun, L Evdokimov, O Fatemi, R Fedorisin, J Fersch, RG Filip, P Finch, E Fine, V Fisyak, Y Gagliardi, CA Gangadharan, DR Geromitsos, A Geurts, F Ghosh, P Gorbunov, YN Gordon, A Grebenyuk, OG Grosnick, D Guertin, SM Gupta, A Guryn, W Haag, B Hajkova, O Hamed, A Han, LX Harris, JW Hays-Wehle, JP Heinz, M Heppelmann, S Hirsch, A Hjort, E Hoffmann, GW Hofman, DJ Huang, B Huang, HZ Humanic, TJ Huo, L Igo, G Jacobs, P Jacobs, WW Jena, C Jin, F Joseph, J Judd, EG Kabana, S Kang, K Kapitan, J Kauder, K Ke, HW Keane, D Kechechyan, A Kettler, D Kikola, DP Kiryluk, J Kisiel, A Kizka, V Klein, SR Knospe, AG Koetke, DD Kollegger, T Konzer, J Koralt, I Koroleva, L Korsch, W Kotchenda, L Kouchpil, V Kravtsov, P Krueger, K Krus, M Kumar, L Kurnadi, P Lamont, MAC Landgraf, JM LaPointe, S Lauret, J Lebedev, A Lednicky, R Lee, JH Leight, W LeVine, MJ Li, C Li, L Li, N Li, W Li, X Li, X Li, Y Li, ZM Lisa, MA Liu, F Liu, H Liu, J Ljubicic, T Llope, WJ Longacre, RS Love, WA Lu, Y Lukashov, EV Luo, X Ma, GL Ma, YG Mahapatra, DP Majka, R Mall, OI Mangotra, LK Manweiler, R Margetis, S Markert, C Masui, H Matis, HS Matulenko, YA McDonald, D McShane, TS Meschanin, A Milner, R Minaev, NG Mioduszewski, S Mischke, A Mitrovski, MK Mohammed, Y Mohanty, B Mondal, MM Morozov, B Morozov, DA Munhoz, MG Mustafa, MK Naglis, M Nandi, BK Nayak, TK Netrakanti, PK Nogach, LV Nurushev, SB Odyniec, G Ogawa, A Oh, K Ohlson, A Okorokov, V Oldag, EW Olson, D Pachr, M Page, BS Pal, SK Pandit, Y Panebratsev, Y Pawlak, T Pei, H Peitzmann, T Perkins, C Peryt, W Phatak, SC Pile, P Planinic, M Ploskon, MA Pluta, J Plyku, D Poljak, N Poskanzer, AM Potukuchi, BVKS Powell, CB Prindle, D Pruneau, C Pruthi, NK Pujahari, PR Putschke, J Qiu, H Raniwala, R Raniwala, S Ray, RL Redwine, R Reed, R Ritter, HG Roberts, JB Rogachevskiy, OV Romero, JL Rose, A Ruan, L Rusnak, J Sahoo, NR Sakai, S Sakrejda, I Salur, S Sandweiss, J Sangaline, E Sarkar, A Schambach, J Scharenberg, RP Schmah, AM Schmitz, N Schuster, TR Seele, J Seger, J Selyuzhenkov, I Seyboth, P Shahaliev, E Shao, M Sharma, M Shi, SS Shou, QY Sichtermann, EP Simon, F Singaraju, RN Skoby, MJ Smirnov, N Sorensen, P Spinka, HM Srivastava, B Stanislaus, TDS Staszak, D Steadman, SG Stevens, JR Stock, R Strikhanov, M Stringfellow, B Suaide, AAP Suarez, MC Subba, NL Sumbera, M Sun, XM Sun, Y Sun, Z Surrow, B Svirida, DN Symons, TJM de Toledo, AS Takahashi, J Tang, AH Tang, Z Tarini, LH Tarnowsky, T Thein, D Thomas, JH Tian, J Timmins, AR Tlusty, D Tokarev, M Trainor, TA Tram, VN Trentalange, S Tribble, RE Tribedy, P Tsai, OD Ullrich, T Underwood, DG Van Buren, G van Nieuwenhuizen, G Vanfossen, JA Varma, R Vasconcelos, GMS Vasiliev, AN Videbaek, F Viyogi, YP Vokal, S Voloshin, SA Wada, M Walker, M Wang, F Wang, G Wang, H Wang, JS Wang, Q Wang, XL Wang, Y Webb, G Webb, JC Westfall, GD Whitten, C Wieman, H Wissink, SW Witt, R Witzke, W Wu, YF Xiao, Z Xie, W Xu, H Xu, N Xu, QH Xu, W Xu, Y Xu, Z Xue, L Yang, Y Yang, Y Yepes, P Yip, K Yoo, IK Zawisza, M Zbroszczyk, H Zhan, W Zhang, JB Zhang, S Zhang, WM Zhang, XP Zhang, Y Zhang, ZP Zhao, J Zhong, C Zhou, W Zhu, X Zhu, YH Zoulkarneev, R Zoulkarneeva, Y AF Agakishiev, H. Aggarwal, M. M. Ahammed, Z. Alakhverdyants, A. V. Alekseev, I. Alford, J. Anderson, B. D. Anson, C. D. Arkhipkin, D. Averichev, G. S. Balewski, J. Beavis, D. R. Behera, N. K. Bellwied, R. Betancourt, M. J. Betts, R. R. Bhasin, A. Bhati, A. K. Bichsel, H. Bielcik, J. Bielcikova, J. Biritz, B. Bland, L. C. Bordyuzhin, I. G. Borowski, W. Bouchet, J. Braidot, E. Brandin, A. V. Bridgeman, A. Brovko, S. G. Bruna, E. Bueltmann, S. Bunzarov, I. Burton, T. P. Cai, X. Z. Caines, H. Sanchez, M. Calderon de la Barca Cebra, D. Cendejas, R. Cervantes, M. C. Chajecki, Z. Chaloupka, P. Chattopadhyay, S. Chen, H. F. Chen, J. H. Chen, J. Y. Chen, L. Cheng, J. Cherney, M. Chikanian, A. Choi, K. E. Christie, W. Chung, P. Codrington, M. J. M. Corliss, R. Cramer, J. G. Crawford, H. J. Dash, S. Leyva, A. Davila De Silva, L. C. Debbe, R. R. Dedovich, T. G. Derevschikov, A. A. Derradi de Souza, R. Didenko, L. Djawotho, P. Dogra, S. M. Dong, X. Drachenberg, J. L. Draper, J. E. Dunlop, J. C. Efimov, L. G. Elnimr, M. Engelage, J. Eppley, G. Estienne, M. Eun, L. Evdokimov, O. Fatemi, R. Fedorisin, J. Fersch, R. G. Filip, P. Finch, E. Fine, V. Fisyak, Y. Gagliardi, C. A. Gangadharan, D. R. Geromitsos, A. Geurts, F. Ghosh, P. Gorbunov, Y. N. Gordon, A. Grebenyuk, O. G. Grosnick, D. Guertin, S. M. Gupta, A. Guryn, W. Haag, B. Hajkova, O. Hamed, A. Han, L-X. Harris, J. W. Hays-Wehle, J. P. Heinz, M. Heppelmann, S. Hirsch, A. Hjort, E. Hoffmann, G. W. Hofman, D. J. Huang, B. Huang, H. Z. Humanic, T. J. Huo, L. Igo, G. Jacobs, P. Jacobs, W. W. Jena, C. Jin, F. Joseph, J. Judd, E. G. Kabana, S. Kang, K. Kapitan, J. Kauder, K. Ke, H. W. Keane, D. Kechechyan, A. Kettler, D. Kikola, D. P. Kiryluk, J. Kisiel, A. Kizka, V. Klein, S. R. Knospe, A. G. Koetke, D. D. Kollegger, T. Konzer, J. Koralt, I. Koroleva, L. Korsch, W. Kotchenda, L. Kouchpil, V. Kravtsov, P. Krueger, K. Krus, M. Kumar, L. Kurnadi, P. Lamont, M. A. C. Landgraf, J. M. LaPointe, S. Lauret, J. Lebedev, A. Lednicky, R. Lee, J. H. Leight, W. LeVine, M. J. Li, C. Li, L. Li, N. Li, W. Li, X. Li, X. Li, Y. Li, Z. M. Lisa, M. A. Liu, F. Liu, H. Liu, J. Ljubicic, T. Llope, W. J. Longacre, R. S. Love, W. A. Lu, Y. Lukashov, E. V. Luo, X. Ma, G. L. Ma, Y. G. Mahapatra, D. P. Majka, R. Mall, O. I. Mangotra, L. K. Manweiler, R. Margetis, S. Markert, C. Masui, H. Matis, H. S. Matulenko, Yu. A. McDonald, D. McShane, T. S. Meschanin, A. Milner, R. Minaev, N. G. Mioduszewski, S. Mischke, A. Mitrovski, M. K. Mohammed, Y. Mohanty, B. Mondal, M. M. Morozov, B. Morozov, D. A. Munhoz, M. G. Mustafa, M. K. Naglis, M. Nandi, B. K. Nayak, T. K. Netrakanti, P. K. Nogach, L. V. Nurushev, S. B. Odyniec, G. Ogawa, A. Oh, K. Ohlson, A. Okorokov, V. Oldag, E. W. Olson, D. Pachr, M. Page, B. S. Pal, S. K. Pandit, Y. Panebratsev, Y. Pawlak, T. Pei, H. Peitzmann, T. Perkins, C. Peryt, W. Phatak, S. C. Pile, P. Planinic, M. Ploskon, M. A. Pluta, J. Plyku, D. Poljak, N. Poskanzer, A. M. Potukuchi, B. V. K. S. Powell, C. B. Prindle, D. Pruneau, C. Pruthi, N. K. Pujahari, P. R. Putschke, J. Qiu, H. Raniwala, R. Raniwala, S. Ray, R. L. Redwine, R. Reed, R. Ritter, H. G. Roberts, J. B. Rogachevskiy, O. V. Romero, J. L. Rose, A. Ruan, L. Rusnak, J. Sahoo, N. R. Sakai, S. Sakrejda, I. Salur, S. Sandweiss, J. Sangaline, E. Sarkar, A. Schambach, J. Scharenberg, R. P. Schmah, A. M. Schmitz, N. Schuster, T. R. Seele, J. Seger, J. Selyuzhenkov, I. Seyboth, P. Shahaliev, E. Shao, M. Sharma, M. Shi, S. S. Shou, Q. Y. Sichtermann, E. P. Simon, F. Singaraju, R. N. Skoby, M. J. Smirnov, N. Sorensen, P. Spinka, H. M. Srivastava, B. Stanislaus, T. D. S. Staszak, D. Steadman, S. G. Stevens, J. R. Stock, R. Strikhanov, M. Stringfellow, B. Suaide, A. A. P. Suarez, M. C. Subba, N. L. Sumbera, M. Sun, X. M. Sun, Y. Sun, Z. Surrow, B. Svirida, D. N. Symons, T. J. M. Szanto de Toledo, A. Takahashi, J. Tang, A. H. Tang, Z. Tarini, L. H. Tarnowsky, T. Thein, D. Thomas, J. H. Tian, J. Timmins, A. R. Tlusty, D. Tokarev, M. Trainor, T. A. Tram, V. N. Trentalange, S. Tribble, R. E. Tribedy, P. Tsai, O. D. Ullrich, T. Underwood, D. G. Van Buren, G. van Nieuwenhuizen, G. Vanfossen, J. A., Jr. Varma, R. Vasconcelos, G. M. S. Vasiliev, A. N. Videbaek, F. Viyogi, Y. P. Vokal, S. Voloshin, S. A. Wada, M. Walker, M. Wang, F. Wang, G. Wang, H. Wang, J. S. Wang, Q. Wang, X. L. Wang, Y. Webb, G. Webb, J. C. Westfall, G. D. Whitten, C., Jr. Wieman, H. Wissink, S. W. Witt, R. Witzke, W. Wu, Y. F. Xiao, Z. Xie, W. Xu, H. Xu, N. Xu, Q. H. Xu, W. Xu, Y. Xu, Z. Xue, L. Yang, Y. Yang, Y. Yepes, P. Yip, K. Yoo, I-K. Zawisza, M. Zbroszczyk, H. Zhan, W. Zhang, J. B. Zhang, S. Zhang, W. M. Zhang, X. P. Zhang, Y. Zhang, Z. P. Zhao, J. Zhong, C. Zhou, W. Zhu, X. Zhu, Y. H. Zoulkarneev, R. Zoulkarneeva, Y. CA STAR Collaboration TI Experimental studies of di-jet survival and surface emission bias in Au plus Au collisions via angular correlations with respect to back-to-back leading hadrons SO PHYSICAL REVIEW C LA English DT Article ID STAR AB We report first results from an analysis based on a new multi-hadron correlation technique, exploring jet-medium interactions and di-jet surface emission bias at the BNL Relativistic Heavy Ion Collider (RHIC). Pairs of back-to-back high-transverse-momentum hadrons are used for triggers to study associated hadron distributions. In contrast with two-and three-particle correlations with a single trigger with similar kinematic selections, the associated hadron distribution of both trigger sides reveals no modification in either relative pseudorapidity Delta eta or relative azimuthal angle Delta phi from d + Au to central Au + Au collisions. We determine associated hadron yields and spectra as well as production rates for such correlated back-to-back triggers to gain additional insights on medium properties. C1 [Agakishiev, H.; Alakhverdyants, A. V.; Averichev, G. S.; Bunzarov, I.; Dedovich, T. G.; Efimov, L. G.; Fedorisin, J.; Filip, P.; Kechechyan, A.; Kizka, V.; Lednicky, R.; Panebratsev, Y.; Rogachevskiy, O. V.; Shahaliev, E.; Tokarev, M.; Vokal, S.; Zoulkarneev, R.; Zoulkarneeva, Y.] Joint Inst Nucl Res, RU-141980 Dubna, Russia. [Bridgeman, A.; Krueger, K.; Spinka, H. M.; Underwood, D. G.] Argonne Natl Lab, Argonne, IL 60439 USA. [Arkhipkin, D.; Beavis, D. R.; Bland, L. C.; Burton, T. P.; Christie, W.; Debbe, R. R.; Didenko, L.; Dunlop, J. C.; Fine, V.; Fisyak, Y.; Gordon, A.; Guryn, W.; Lamont, M. A. C.; Landgraf, J. M.; Lauret, J.; Lebedev, A.; Lee, J. H.; LeVine, M. J.; Ljubicic, T.; Longacre, R. S.; Love, W. A.; Ogawa, A.; Pile, P.; Ruan, L.; Sorensen, P.; Tang, A. H.; Ullrich, T.; Van Buren, G.; Videbaek, F.; Webb, J. C.; Xu, Z.; Yip, K.] Brookhaven Natl Lab, Upton, NY 11973 USA. [Brovko, S. G.; Sanchez, M. Calderon de la Barca; Cebra, D.; Draper, J. E.; Haag, B.; Liu, H.; Mall, O. I.; Reed, R.; Romero, J. L.; Salur, S.; Sangaline, E.] Univ Calif Davis, Davis, CA 95616 USA. [Biritz, B.; Cendejas, R.; Gangadharan, D. R.; Guertin, S. M.; Huang, H. Z.; Igo, G.; Kurnadi, P.; Staszak, D.; Trentalange, S.; Tsai, O. D.; Wang, G.; Whitten, C., Jr.; Xu, W.] Univ Calif Los Angeles, Los Angeles, CA 90095 USA. [Derradi de Souza, R.; Takahashi, J.; Vasconcelos, G. M. S.] Univ Estadual Campinas, Sao Paulo, Brazil. [Betts, R. R.; Evdokimov, O.; Hofman, D. J.; Kauder, K.; Pei, H.; Suarez, M. C.] Univ Illinois, Chicago, IL 60607 USA. [Cherney, M.; Gorbunov, Y. N.; McShane, T. S.; Seger, J.] Creighton Univ, Omaha, NE 68178 USA. [Bielcik, J.; Hajkova, O.; Krus, M.; Pachr, M.] Czech Tech Univ, FNSPE, CZ-11519 Prague, Czech Republic. [Bielcikova, J.; Chaloupka, P.; Chung, P.; Kapitan, J.; Kouchpil, V.; Rusnak, J.; Sumbera, M.; Tlusty, D.] Nucl Phys Inst AS CR, Rez 25068, Czech Republic. [Kollegger, T.; Mitrovski, M. K.; Schuster, T. R.; Stock, R.] Goethe Univ Frankfurt, Frankfurt, Germany. [Dash, S.; Jena, C.; Mahapatra, D. P.; Phatak, S. C.] Inst Phys, Bhubaneswar 751005, Orissa, India. [Behera, N. K.; Nandi, B. K.; Pujahari, P. R.; Sarkar, A.; Varma, R.] Indian Inst Technol, Bombay 400076, Maharashtra, India. [Jacobs, W. W.; Page, B. S.; Selyuzhenkov, I.; Stevens, J. R.; Wissink, S. W.] Indiana Univ, Bloomington, IN USA. [Alekseev, I.; Bordyuzhin, I. G.; Koroleva, L.; Morozov, B.; Svirida, D. N.] Alikhanov Inst Theoret & Expt Phys, Moscow, Russia. [Bhasin, A.; Dogra, S. M.; Gupta, A.; Mangotra, L. K.; Potukuchi, B. V. K. S.] Univ Jammu, Jammu 180001, India. [Alford, J.; Anderson, B. D.; Bouchet, J.; Joseph, J.; Keane, D.; Kumar, L.; Margetis, S.; Pandit, Y.; Subba, N. L.; Vanfossen, J. A., Jr.; Zhang, W. M.] Kent State Univ, Kent, OH 44242 USA. [Fatemi, R.; Fersch, R. G.; Korsch, W.; Webb, G.; Witzke, W.] Univ Kentucky, Lexington, KY 40506 USA. [Qiu, H.; Sun, Z.; Wang, J. S.; Xu, H.; Yang, Y.; Zhan, W.] Inst Modern Phys, Lanzhou, Peoples R China. [Ahammed, Z.; Dong, X.; Grebenyuk, O. G.; Hjort, E.; Jacobs, P.; Kikola, D. P.; Kiryluk, J.; Klein, S. R.; Masui, H.; Matis, H. S.; Naglis, M.; Odyniec, G.; Olson, D.; Ploskon, M. A.; Poskanzer, A. M.; Powell, C. B.; Ritter, H. G.; Rose, A.; Sakai, S.; Sakrejda, I.; Schmah, A. M.; Sichtermann, E. P.; Sun, X. M.; Symons, T. J. M.; Thomas, J. H.; Tram, V. N.; Wieman, H.; Xu, N.; Zhang, Y.] Univ Calif Berkeley, Lawrence Berkeley Lab, Berkeley, CA 94720 USA. [Balewski, J.; Betancourt, M. J.; Corliss, R.; Hays-Wehle, J. P.; Leight, W.; Milner, R.; Redwine, R.; Seele, J.; Steadman, S. G.; Surrow, B.; van Nieuwenhuizen, G.; Walker, M.] MIT, Cambridge, MA 02139 USA. [Schmitz, N.; Seyboth, P.; Simon, F.] Max Planck Inst Phys & Astrophys, D-80805 Munich, Germany. [Tarnowsky, T.; Wang, H.; Westfall, G. D.] Michigan State Univ, E Lansing, MI 48824 USA. [Brandin, A. V.; Kotchenda, L.; Kravtsov, P.; Lukashov, E. V.; Okorokov, V.; Strikhanov, M.] Moscow Engn Phys Inst, Moscow 115409, Russia. [Braidot, E.; Mischke, A.; Peitzmann, T.] NIKHEF, Amsterdam, Netherlands. [Braidot, E.; Mischke, A.; Peitzmann, T.] Univ Utrecht, Amsterdam, Netherlands. [Anson, C. D.; Chajecki, Z.; Humanic, T. J.; Lisa, M. A.] Ohio State Univ, Columbus, OH 43210 USA. [Bueltmann, S.; Koralt, I.; Plyku, D.] Old Dominion Univ, Norfolk, VA 23529 USA. [Aggarwal, M. M.; Bhati, A. K.; Pruthi, N. K.] Panjab Univ, Chandigarh 160014, India. [Eun, L.; Heppelmann, S.] Penn State Univ, University Pk, PA 16802 USA. [Derevschikov, A. A.; Matulenko, Yu. A.; Meschanin, A.; Minaev, N. G.; Morozov, D. A.; Nogach, L. V.; Nurushev, S. B.; Vasiliev, A. N.] Inst High Energy Phys, Protvino, Russia. [Hirsch, A.; Konzer, J.; Li, X.; Mustafa, M. K.; Netrakanti, P. K.; Scharenberg, R. P.; Skoby, M. J.; Srivastava, B.; Stringfellow, B.; Wang, F.; Wang, Q.; Xie, W.] Purdue Univ, W Lafayette, IN 47907 USA. [Choi, K. E.; Oh, K.; Yoo, I-K.] Pusan Natl Univ, Pusan 609735, South Korea. [Raniwala, R.; Raniwala, S.] Univ Rajasthan, Jaipur 302004, Rajasthan, India. [Eppley, G.; Geurts, F.; Liu, J.; Llope, W. J.; McDonald, D.; Roberts, J. B.; Yepes, P.] Rice Univ, Houston, TX 77251 USA. [Munhoz, M. G.; Suaide, A. A. P.; Szanto de Toledo, A.] Univ Sao Paulo, Sao Paulo, Brazil. [Chen, H. F.; Huang, B.; Li, C.; Lu, Y.; Luo, X.; Shao, M.; Sun, Y.; Tang, Z.; Wang, X. L.; Xu, Y.; Zhang, Z. P.] Univ Sci & Technol China, Hefei 230026, Peoples R China. [Li, X.; Xu, Q. H.; Zhou, W.] Shandong Univ, Jinan 250100, Shandong, Peoples R China. [Cai, X. Z.; Chen, J. H.; Han, L-X.; Jin, F.; Li, W.; Ma, G. L.; Ma, Y. G.; Shou, Q. Y.; Tian, J.; Xue, L.; Zhang, S.; Zhao, J.; Zhong, C.; Zhu, Y. H.] Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China. [Borowski, W.; Estienne, M.; Geromitsos, A.; Kabana, S.] SUBATECH, Nantes, France. [Cervantes, M. C.; Codrington, M. J. M.; Djawotho, P.; Drachenberg, J. L.; Gagliardi, C. A.; Hamed, A.; Huo, L.; Mioduszewski, S.; Mohammed, Y.; Tribble, R. E.] Texas A&M Univ, College Stn, TX 77843 USA. [Leyva, A. Davila; Hoffmann, G. W.; Li, L.; Markert, C.; Oldag, E. W.; Ray, R. L.; Schambach, J.; Thein, D.; Wada, M.] Univ Texas Austin, Austin, TX 78712 USA. [Bellwied, R.; De Silva, L. C.; Timmins, A. R.] Univ Houston, Houston, TX 77204 USA. [Cheng, J.; Kang, K.; Li, Y.; Wang, Y.; Xiao, Z.; Zhang, X. P.; Zhu, X.] Tsinghua Univ, Beijing 100084, Peoples R China. [Witt, R.] USN Acad, Annapolis, MD 21402 USA. [Grosnick, D.; Koetke, D. D.; Manweiler, R.; Stanislaus, T. D. S.] Valparaiso Univ, Valparaiso, IN 46383 USA. [Chattopadhyay, S.; Ghosh, P.; Mohanty, B.; Mondal, M. M.; Nayak, T. K.; Pal, S. K.; Sahoo, N. R.; Singaraju, R. N.; Tribedy, P.; Viyogi, Y. P.] Ctr Variable Energy Cyclotron, Kolkata 700064, India. [Kisiel, A.; Pawlak, T.; Peryt, W.; Pluta, J.; Zawisza, M.; Zbroszczyk, H.] Warsaw Univ Technol, Warsaw, Poland. [Bichsel, H.; Cramer, J. G.; Kettler, D.; Prindle, D.; Trainor, T. A.] Univ Washington, Seattle, WA 98195 USA. [Elnimr, M.; LaPointe, S.; Pruneau, C.; Sharma, M.; Tarini, L. H.; Voloshin, S. A.] Wayne State Univ, Detroit, MI 48201 USA. [Chen, J. Y.; Chen, L.; Ke, H. W.; Li, N.; Li, Z. M.; Liu, F.; Shi, S. S.; Wu, Y. F.; Yang, Y.; Zhang, J. B.] CCNU HZNU, Inst Particle Phys, Wuhan 430079, Peoples R China. [Bruna, E.; Caines, H.; Chikanian, A.; Finch, E.; Harris, J. W.; Heinz, M.; Knospe, A. G.; Majka, R.; Ohlson, A.; Putschke, J.; Sandweiss, J.; Smirnov, N.] Yale Univ, New Haven, CT 06520 USA. [Planinic, M.; Poljak, N.] Univ Zagreb, HR-10002 Zagreb, Croatia. RP Agakishiev, H (reprint author), Joint Inst Nucl Res, RU-141980 Dubna, Russia. RI Sumbera, Michal/O-7497-2014; Strikhanov, Mikhail/P-7393-2014; Xu, Wenqin/H-7553-2014; XIAO, Zhigang/C-3788-2015; Bruna, Elena/C-4939-2014; Dogra, Sunil /B-5330-2013; Chaloupka, Petr/E-5965-2012; Huang, Bingchu/H-6343-2015; Derradi de Souza, Rafael/M-4791-2013; Suaide, Alexandre/L-6239-2016; Svirida, Dmitry/R-4909-2016; Inst. of Physics, Gleb Wataghin/A-9780-2017; Okorokov, Vitaly/C-4800-2017; Ma, Yu-Gang/M-8122-2013; Mischke, Andre/D-3614-2011; Bielcikova, Jana/G-9342-2014; Alekseev, Igor/J-8070-2014; Takahashi, Jun/B-2946-2012; Planinic, Mirko/E-8085-2012; Yoo, In-Kwon/J-6222-2012; Peitzmann, Thomas/K-2206-2012; Witt, Richard/H-3560-2012; Yip, Kin/D-6860-2013; Xue, Liang/F-8077-2013; Voloshin, Sergei/I-4122-2013; Lednicky, Richard/K-4164-2013; Yang, Yanyun/B-9485-2014; Rusnak, Jan/G-8462-2014 OI Sumbera, Michal/0000-0002-0639-7323; Strikhanov, Mikhail/0000-0003-2586-0405; Xu, Wenqin/0000-0002-5976-4991; Bruna, Elena/0000-0001-5427-1461; Huang, Bingchu/0000-0002-3253-3210; Derradi de Souza, Rafael/0000-0002-2084-7001; Suaide, Alexandre/0000-0003-2847-6556; Okorokov, Vitaly/0000-0002-7162-5345; Ma, Yu-Gang/0000-0002-0233-9900; Alekseev, Igor/0000-0003-3358-9635; Takahashi, Jun/0000-0002-4091-1779; Peitzmann, Thomas/0000-0002-7116-899X; Yip, Kin/0000-0002-8576-4311; Xue, Liang/0000-0002-2321-9019; Yang, Yanyun/0000-0002-5982-1706; FU RHIC Operations Group; RCF at BNL; NERSC Center at LBNL; Open Science Grid consortium; Offices of NP; HEP within the US DOE Office of Science; US NSF; Sloan Foundation; DFG cluster of excellence "Origin and Structure of the Universe" of Germany; CNRS/IN2P3; FAPESP CNPq of Brazil; Ministry of Ed. and Sci. of the Russian Federation; NNSFC; CAS; MoST; MoE of China; GA; MSMT of the Czech Republic; FOM; NWO of the Netherlands; DAE; DST; CSIR of India; Polish Ministry of Sci. and Higher Ed.; Korea Research Foundation; Ministry of Sci., Ed. and Sports of the Rep. Of Croatia; RosAtom of Russia FX We thank the RHIC Operations Group and RCF at BNL, the NERSC Center at LBNL, and the Open Science Grid consortium for providing resources and support. This work was supported in part by the Offices of NP and HEP within the US DOE Office of Science, the US NSF, the Sloan Foundation, the DFG cluster of excellence "Origin and Structure of the Universe" of Germany, CNRS/IN2P3, FAPESP CNPq of Brazil, Ministry of Ed. and Sci. of the Russian Federation, NNSFC, CAS, MoST, and MoE of China, GA and MSMT of the Czech Republic, FOM and NWO of the Netherlands, DAE, DST, and CSIR of India, Polish Ministry of Sci. and Higher Ed., Korea Research Foundation, Ministry of Sci., Ed. and Sports of the Rep. Of Croatia, and RosAtom of Russia. NR 29 TC 6 Z9 6 U1 0 U2 12 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0556-2813 EI 1089-490X J9 PHYS REV C JI Phys. Rev. C PD JUN 10 PY 2011 VL 83 IS 6 AR 061901 DI 10.1103/PhysRevC.83.061901 PG 6 WC Physics, Nuclear SC Physics GA 775MN UT WOS:000291463700001 ER PT J AU Herd, CDK Blinova, A Simkus, DN Huang, YS Tarozo, R Alexander, CMO Gyngard, F Nittler, LR Cody, GD Fogel, ML Kebukawa, Y Kilcoyne, ALD Hilts, RW Slater, GF Glavin, DP Dworkin, JP Callahan, MP Elsila, JE De Gregorio, BT Stroud, RM AF Herd, Christopher D. K. Blinova, Alexandra Simkus, Danielle N. Huang, Yongsong Tarozo, Rafael Alexander, Conel M. O'D. Gyngard, Frank Nittler, Larry R. Cody, George D. Fogel, Marilyn L. Kebukawa, Yoko Kilcoyne, A. L. David Hilts, Robert W. Slater, Greg F. Glavin, Daniel P. Dworkin, Jason P. Callahan, Michael P. Elsila, Jamie E. De Gregorio, Bradley T. Stroud, Rhonda M. TI Origin and Evolution of Prebiotic Organic Matter As Inferred from the Tagish Lake Meteorite SO SCIENCE LA English DT Article ID MURCHISON METEORITE; CARBONACEOUS CHONDRITE; MONOCARBOXYLIC ACIDS; HYDROUS PYROLYSIS; AMINO-ACIDS; ISOVALINE AB The complex suite of organic materials in carbonaceous chondrite meteorites probably originally formed in the interstellar medium and/or the solar protoplanetary disk, but was subsequently modified in the meteorites' asteroidal parent bodies. The mechanisms of formation and modification are still very poorly understood. We carried out a systematic study of variations in the mineralogy, petrology, and soluble and insoluble organic matter in distinct fragments of the Tagish Lake meteorite. The variations correlate with indicators of parent body aqueous alteration. At least some molecules of prebiotic importance formed during the alteration. C1 [Herd, Christopher D. K.; Blinova, Alexandra; Simkus, Danielle N.] Univ Alberta, Dept Earth & Atmospher Sci, Edmonton, AB T6G 2E3, Canada. [Huang, Yongsong; Tarozo, Rafael] Brown Univ, Dept Geol Sci, Providence, RI 02912 USA. [Alexander, Conel M. O'D.; Gyngard, Frank; Nittler, Larry R.] Carnegie Inst Washington, Dept Terr Magnetism, Washington, DC 20015 USA. [Cody, George D.; Fogel, Marilyn L.; Kebukawa, Yoko] Carnegie Inst Washington, Geophys Lab, Washington, DC 20015 USA. [Kilcoyne, A. L. David] Univ Calif Berkeley, Lawrence Berkeley Lab, Adv Light Source, Berkeley, CA 94720 USA. [Hilts, Robert W.] Grant MacEwan Univ, Dept Phys Sci, Edmonton, AB T5J 4S2, Canada. [Slater, Greg F.] McMaster Univ, Sch Geog & Earth Sci, Hamilton, ON L8S 4K1, Canada. [Glavin, Daniel P.; Dworkin, Jason P.; Callahan, Michael P.; Elsila, Jamie E.] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA. [De Gregorio, Bradley T.] NASA, Lyndon B Johnson Space Ctr, Engn & Sci Contract Grp, Houston, TX 77058 USA. [De Gregorio, Bradley T.; Stroud, Rhonda M.] USN, Res Lab, Washington, DC 20375 USA. RP Herd, CDK (reprint author), Univ Alberta, Dept Earth & Atmospher Sci, Edmonton, AB T6G 2E3, Canada. EM herd@ualberta.ca RI Elsila, Jamie/C-9952-2012; Callahan, Michael/D-3630-2012; Slater, Greg/B-5163-2013; De Gregorio, Bradley/B-8465-2008; Glavin, Daniel/D-6194-2012; Alexander, Conel/N-7533-2013; Fogel, Marilyn/M-2395-2015; Dworkin, Jason/C-9417-2012; Kebukawa, Yoko/A-7315-2010; Kilcoyne, David/I-1465-2013; Stroud, Rhonda/C-5503-2008 OI Slater, Greg/0000-0001-7418-7566; De Gregorio, Bradley/0000-0001-9096-3545; Glavin, Daniel/0000-0001-7779-7765; Alexander, Conel/0000-0002-8558-1427; Fogel, Marilyn/0000-0002-1176-3818; Dworkin, Jason/0000-0002-3961-8997; Kebukawa, Yoko/0000-0001-8430-3612; Stroud, Rhonda/0000-0001-5242-8015 FU Natural Sciences and Engineering Research Council of Canada; Alberta Innovates; NASA; U.S. Office of Naval Research; CIW; Grant MacEwan University; Carnegie Institution of Canada; U.S. Department of Energy [DE-AC02-05CH11231]; W.M. Keck Foundation FX Funding for this study was provided by the Natural Sciences and Engineering Research Council of Canada, Alberta Innovates, NASA (Astrobiology, including Carnegie Institution Astrobiology and the Goddard Center for Astrobiology; Origins of Solar Systems; Cosmochemistry and Postdoctoral Programs), the U.S. Office of Naval Research, the CIW, Grant MacEwan University, and the Carnegie Institution of Canada. The Canadian Institute for Advanced Research is thanked for hosting workshops that facilitated work on the MCAs. J. Kirby assisted with MCA analysis. R. Bowden carried out bulk IOM analyses. XANES data were acquired on the Scanning Transmission X-ray Microscope at beamline 5.3.2.2 of the Advanced Light Source, which is supported by the Director of the Office of Science, U.S. Department of Energy, under contract no. DE-AC02-05CH11231, and by a W.M. Keck Foundation grant to the CIW. Three anonymous reviewers are thanked for constructive comments that improved the manuscript. NR 37 TC 86 Z9 87 U1 4 U2 56 PU AMER ASSOC ADVANCEMENT SCIENCE PI WASHINGTON PA 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005 USA SN 0036-8075 J9 SCIENCE JI Science PD JUN 10 PY 2011 VL 332 IS 6035 BP 1304 EP 1307 DI 10.1126/science.1203290 PG 4 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA 775EP UT WOS:000291441700041 PM 21659601 ER PT J AU Abdo, AA Ackermann, M Ajello, M Allafort, A Baldini, L Ballet, J Barbiellini, G Baring, MG Bastieri, D Bellazzini, R Berenji, B Blandford, RD Bloom, ED Bonamente, E Borgland, AW Bouvier, A Brandt, TJ Bregeon, J Brigida, M Bruel, P Buehler, R Buson, S Caliandro, GA Cameron, RA Caraveo, PA Casandjian, JM Cecchi, C Chaty, S Chekhtman, A Cheung, CC Chiang, J Cillis, AN Ciprini, S Claus, R Cohen-Tanugi, J Conrad, J Corbel, S Cutini, S de Angelis, A de Palma, F Dermer, CD Digel, SW Silva, EDE Drell, PS Drlica-Wagner, A Dubois, R Dumora, D Favuzzi, C Ferrara, EC Fortin, P Frailis, M Fukazawa, Y Fukui, Y Funk, S Fusco, P Gargano, F Gasparrini, D Gehrels, N Germani, S Giglietto, N Giordano, F Giroletti, M Glanzman, T Godfrey, G Grenier, IA Grondin, MH Guiriec, S Hadasch, D Hanabata, Y Harding, AK Hayashida, M Hayashi, K Hays, E Horan, D Jackson, MS Johannesson, G Johnson, AS Kamae, T Katagiri, H Kataoka, J Kerr, M Knodlseder, J Kuss, M Lande, J Latronico, L Lee, SH Lemoine-Goumard, M Longo, F Loparco, F Lovellette, MN Lubrano, P Madejski, GM Makeev, A Mazziotta, MN McEnery, JE Michelson, PF Mignani, RP Mitthumsiri, W Mizuno, T Moiseev, AA Monte, C Monzani, ME Morselli, A Moskalenko, IV Murgia, S Naumann-Godo, M Nolan, PL Norris, JP Nuss, E Ohsugi, T Okumura, A Orlando, E Ormes, JF Paneque, D Parent, D Pelassa, V Pesce-Rollins, M Pierbattista, M Piron, F Pohl, M Porter, TA Raino, S Rando, R Razzano, M Reimer, O Reposeur, T Ritz, S Romani, RW Roth, M Sadrozinski, HFW Parkinson, PMS Sgro, C Smith, DA Smith, PD Spandre, G Spinelli, P Strickman, MS Tajima, H Takahashi, H Takahashi, T Tanaka, T Thayer, JG Thayer, JB Thompson, DJ Tibaldo, L Tibolla, O Torres, DF Tosti, G Tramacere, A Troja, E Uchiyama, Y Vandenbroucke, J Vasileiou, V Vianello, G Vilchez, N Vitale, V Waite, AP Wang, P Winer, BL Wood, KS Yamamoto, H Yamazaki, R Yang, Z Ziegler, M AF Abdo, A. A. Ackermann, M. Ajello, M. Allafort, A. Baldini, L. Ballet, J. Barbiellini, G. Baring, M. G. Bastieri, D. Bellazzini, R. Berenji, B. Blandford, R. D. Bloom, E. D. Bonamente, E. Borgland, A. W. Bouvier, A. Brandt, T. J. Bregeon, J. Brigida, M. Bruel, P. Buehler, R. Buson, S. Caliandro, G. A. Cameron, R. A. Caraveo, P. A. Casandjian, J. M. Cecchi, C. Chaty, S. Chekhtman, A. Cheung, C. C. Chiang, J. Cillis, A. N. Ciprini, S. Claus, R. Cohen-Tanugi, J. Conrad, J. Corbel, S. Cutini, S. de Angelis, A. de Palma, F. Dermer, C. D. Digel, S. W. do Couto e Silva, E. Drell, P. S. Drlica-Wagner, A. Dubois, R. Dumora, D. Favuzzi, C. Ferrara, E. C. Fortin, P. Frailis, M. Fukazawa, Y. Fukui, Y. Funk, S. Fusco, P. Gargano, F. Gasparrini, D. Gehrels, N. Germani, S. Giglietto, N. Giordano, F. Giroletti, M. Glanzman, T. Godfrey, G. Grenier, I. A. Grondin, M. -H. Guiriec, S. Hadasch, D. Hanabata, Y. Harding, A. K. Hayashida, M. Hayashi, K. Hays, E. Horan, D. Jackson, M. S. Johannesson, G. Johnson, A. S. Kamae, T. Katagiri, H. Kataoka, J. Kerr, M. Knoedlseder, J. Kuss, M. Lande, J. Latronico, L. Lee, S. -H. Lemoine-Goumard, M. Longo, F. Loparco, F. Lovellette, M. N. Lubrano, P. Madejski, G. M. Makeev, A. Mazziotta, M. N. McEnery, J. E. Michelson, P. F. Mignani, R. P. Mitthumsiri, W. Mizuno, T. Moiseev, A. A. Monte, C. Monzani, M. E. Morselli, A. Moskalenko, I. V. Murgia, S. Naumann-Godo, M. Nolan, P. L. Norris, J. P. Nuss, E. Ohsugi, T. Okumura, A. Orlando, E. Ormes, J. F. Paneque, D. Parent, D. Pelassa, V. Pesce-Rollins, M. Pierbattista, M. Piron, F. Pohl, M. Porter, T. A. Raino, S. Rando, R. Razzano, M. Reimer, O. Reposeur, T. Ritz, S. Romani, R. W. Roth, M. Sadrozinski, H. F. -W. Parkinson, P. M. Saz Sgro, C. Smith, D. A. Smith, P. D. Spandre, G. Spinelli, P. Strickman, M. S. Tajima, H. Takahashi, H. Takahashi, T. Tanaka, T. Thayer, J. G. Thayer, J. B. Thompson, D. J. Tibaldo, L. Tibolla, O. Torres, D. F. Tosti, G. Tramacere, A. Troja, E. Uchiyama, Y. Vandenbroucke, J. Vasileiou, V. Vianello, G. Vilchez, N. Vitale, V. Waite, A. P. Wang, P. Winer, B. L. Wood, K. S. Yamamoto, H. Yamazaki, R. Yang, Z. Ziegler, M. TI OBSERVATIONS OF THE YOUNG SUPERNOVA REMNANT RX J1713.7-3946 WITH THE FERMI LARGE AREA TELESCOPE SO ASTROPHYSICAL JOURNAL LA English DT Article DE acceleration of particles; gamma rays: general; gamma rays: ISM; ISM: individual objects (RX J1713.7-3946); ISM: supernova remnants; radiation mechanisms: non-thermal ID X-RAY-EMISSION; MOLECULAR CLOUDS; COSMIC-RAYS; PARTICLE-ACCELERATION; SHOCK ACCELERATION; CASSIOPEIA-A; SHELL; G347.3-0.5; DISCOVERY; TEV AB We present observations of the young supernova remnant (SNR) RX J1713.7-3946 with the Fermi Large Area Telescope (LAT). We clearly detect a source positionally coincident with the SNR. The source is extended with a best-fit extension of 0 degrees.55 +/- 0 degrees.04 matching the size of the non-thermal X-ray and TeV gamma-ray emission from the remnant. The positional coincidence and the matching extended emission allow us to identify the LAT source with SNR RX J1713.7-3946. The spectrum of the source can be described by a very hard power law with a photon index of Gamma = 1.5 +/- 0.1 that coincides in normalization with the steeper H. E. S. S.-detected gamma-ray spectrum at higher energies. The broadband gamma-ray emission is consistent with a leptonic origin as the dominant mechanism for the gamma-ray emission. C1 [Abdo, A. A.; Makeev, A.; Parent, D.] George Mason Univ, Coll Sci, Ctr Earth Observing & Space Res, Fairfax, VA 22030 USA. [Ackermann, M.; Ajello, M.; Allafort, A.; Berenji, B.; Blandford, R. D.; Bloom, E. D.; Borgland, A. W.; Buehler, R.; Cameron, R. A.; Chiang, J.; Claus, R.; Digel, S. W.; do Couto e Silva, E.; Drell, P. S.; Drlica-Wagner, A.; Dubois, R.; Funk, S.; Glanzman, T.; Godfrey, G.; Hayashida, M.; Johnson, A. S.; Kamae, T.; Kerr, M.; Lande, J.; Lee, S. -H.; Madejski, G. M.; Michelson, P. F.; Mitthumsiri, W.; Monzani, M. E.; Moskalenko, I. V.; Murgia, S.; Nolan, P. L.; Orlando, E.; Paneque, D.; Porter, T. A.; Reimer, O.; Romani, R. W.; Tajima, H.; Tanaka, T.; Thayer, J. G.; Thayer, J. B.; Tramacere, A.; Uchiyama, Y.; Vandenbroucke, J.; Vianello, G.; Waite, A. P.; Wang, P.] Stanford Univ, Dept Phys, Kavli Inst Particle Astrophys & Cosmol, WW Hansen Expt Phys Lab, Stanford, CA 94305 USA. [Ackermann, M.; Ajello, M.; Allafort, A.; Berenji, B.; Blandford, R. D.; Bloom, E. D.; Borgland, A. W.; Buehler, R.; Cameron, R. A.; Chiang, J.; Claus, R.; Digel, S. W.; do Couto e Silva, E.; Drell, P. S.; Drlica-Wagner, A.; Dubois, R.; Funk, S.; Glanzman, T.; Godfrey, G.; Hayashida, M.; Johnson, A. S.; Kamae, T.; Kerr, M.; Lande, J.; Lee, S. -H.; Madejski, G. M.; Michelson, P. F.; Mitthumsiri, W.; Monzani, M. E.; Moskalenko, I. V.; Murgia, S.; Nolan, P. L.; Orlando, E.; Paneque, D.; Porter, T. A.; Reimer, O.; Romani, R. W.; Tajima, H.; Tanaka, T.; Thayer, J. G.; Thayer, J. B.; Tramacere, A.; Uchiyama, Y.; Vandenbroucke, J.; Vianello, G.; Waite, A. P.; Wang, P.] Stanford Univ, SLAC Natl Accelerator Lab, Stanford, CA 94305 USA. [Baldini, L.; Bellazzini, R.; Bregeon, J.; Kuss, M.; Latronico, L.; Pesce-Rollins, M.; Razzano, M.; Sgro, C.; Spandre, G.] Ist Nazl Fis Nucl, Sez Pisa, I-56127 Pisa, Italy. [Ballet, J.; Casandjian, J. M.; Chaty, S.; Corbel, S.; Grenier, I. A.; Naumann-Godo, M.; Pierbattista, M.; Tibaldo, L.] CEA IRFU CNRS Univ Paris Diderot, Serv Astrophys, CEA Saclay, Lab AIM, F-91191 Gif Sur Yvette, France. [Barbiellini, G.; Longo, F.] Ist Nazl Fis Nucl, Sez Trieste, I-34127 Trieste, Italy. [Barbiellini, G.; Longo, F.] Univ Trieste, Dipartimento Fis, I-34127 Trieste, Italy. [Baring, M. G.] Rice Univ, Dept Phys & Astron, Houston, TX 77251 USA. [Bastieri, D.; Buson, S.; Rando, R.; Tibaldo, L.] Ist Nazl Fis Nucl, Sez Padova, I-35131 Padua, Italy. [Bastieri, D.; Buson, S.; Rando, R.; Tibaldo, L.] Univ Padua, Dipartimento Fis G Galilei, I-35131 Padua, Italy. [Bonamente, E.; Cecchi, C.; Germani, S.; Lubrano, P.; Tosti, G.] Ist Nazl Fis Nucl, Sez Perugia, I-06123 Perugia, Italy. [Bonamente, E.; Cecchi, C.; Ciprini, S.; Germani, S.; Lubrano, P.; Tosti, G.] Univ Perugia, Dipartimento Fis, I-06123 Perugia, Italy. [Bouvier, A.; Ritz, S.; Sadrozinski, H. F. -W.; Parkinson, P. M. Saz; Ziegler, M.] Univ Calif Santa Cruz, Santa Cruz Inst Particle Phys, Dept Phys, Santa Cruz, CA 95064 USA. [Bouvier, A.; Ritz, S.; Sadrozinski, H. F. -W.; Parkinson, P. M. Saz; Ziegler, M.] Univ Calif Santa Cruz, Dept Astron & Astrophys, Santa Cruz, CA 95064 USA. [Brandt, T. J.; Knoedlseder, J.; Vilchez, N.] CNRS, IRAP, F-31028 Toulouse 4, France. [Brandt, T. J.; Knoedlseder, J.; Vilchez, N.] Univ Toulouse, UPS OMP, IRAP, Toulouse, France. [Brandt, T. J.; Smith, P. D.; Winer, B. L.] Ohio State Univ, Ctr Cosmol & Astroparticle Phys, Dept Phys, Columbus, OH 43210 USA. [Brigida, M.; de Palma, F.; Favuzzi, C.; Fusco, P.; Giglietto, N.; Giordano, F.; Loparco, F.; Monte, C.; Raino, S.; Spinelli, P.] Univ Politecn Bari, Dipartimento Fis M Merlin, I-70126 Bari, Italy. [Brigida, M.; de Palma, F.; Favuzzi, C.; Fusco, P.; Gargano, F.; Giglietto, N.; Giordano, F.; Loparco, F.; Mazziotta, M. N.; Monte, C.; Raino, S.; Spinelli, P.] Ist Nazl Fis Nucl, Sez Bari, I-70126 Bari, Italy. [Bruel, P.; Fortin, P.; Horan, D.] Ecole Polytech, CNRS IN2P3, Lab Leprince Ringuet, Palaiseau, France. [Caliandro, G. A.; Hadasch, D.; Torres, D. F.] Inst Ciencies Espai IEEC CSIC, Barcelona 08193, Spain. [Caraveo, P. A.] INAF Ist Astrofis Spaziale & Fis Cosm, I-20133 Milan, Italy. [Chekhtman, A.] Artep Inc, Ellicott City, MD 21042 USA. [Cheung, C. C.] Natl Acad Sci, Washington, DC 20001 USA. [Cillis, A. N.] Inst Astron & Fis Espacio, Buenos Aires, DF, Argentina. [Cillis, A. N.; Ferrara, E. C.; Gehrels, N.; Harding, A. K.; Hays, E.; McEnery, J. E.; Moiseev, A. A.; Thompson, D. J.; Troja, E.] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA. [Cohen-Tanugi, J.; Nuss, E.; Pelassa, V.; Piron, F.; Vasileiou, V.] Univ Montpellier 2, Lab Phys Theor & Astroparticules, CNRS IN2P3, Montpellier, France. [Conrad, J.; Yang, Z.] Stockholm Univ, Dept Phys, SE-10691 Stockholm, Sweden. [Conrad, J.; Jackson, M. S.; Yang, Z.] Oskar Klein Ctr Cosmoparticle Phys, SE-10691 Stockholm, Sweden. [Corbel, S.] Inst Univ France, F-75005 Paris, France. [Cutini, S.; Gasparrini, D.] Agenzia Spaziale Italiana ASI, Sci Data Ctr, I-00044 Rome, Italy. [de Angelis, A.; Frailis, M.] Univ Udine, Dipartimento Fis, I-33100 Udine, Italy. [de Angelis, A.; Frailis, M.] Ist Nazl Fis Nucl, Sez Trieste, Grp Coll Udine, I-33100 Udine, Italy. [Dermer, C. D.; Lovellette, M. N.; Strickman, M. S.; Wood, K. S.] USN, Div Space Sci, Res Lab, Washington, DC 20375 USA. [Dumora, D.; Lemoine-Goumard, M.; Reposeur, T.; Smith, D. A.] Univ Bordeaux 1, CNRS IN2p3, Ctr Etud Nucl Bordeaux Gradignan, F-33175 Gradignan, France. [Frailis, M.] Ist Nazl Astrofis, Osservatorio Astron Trieste, I-34143 Trieste, Italy. [Fukazawa, Y.; Hanabata, Y.; Hayashi, K.; Katagiri, H.; Mizuno, T.] Hiroshima Univ, Dept Phys Sci, Hiroshima 7398526, Japan. [Fukui, Y.; Yamamoto, H.] Nagoya Univ, Dept Phys & Astrophys, Chikusa Ku, Nagoya, Aichi 4648602, Japan. [Giroletti, M.] INAF Ist Radioastron, I-40129 Bologna, Italy. [Grondin, M. -H.] Univ Tubingen, Inst Astron & Astrophys, D-72076 Tubingen, Germany. [Guiriec, S.] Univ Alabama, CSPAR, Huntsville, AL 35899 USA. [Jackson, M. S.] Royal Inst Technol KTH, Dept Phys, SE-10691 Stockholm, Sweden. [Johannesson, G.] Univ Iceland, Inst Sci, IS-107 Reykjavik, Iceland. [Kataoka, J.] Waseda Univ, Res Inst Sci & Engn, Shinjuku Ku, Tokyo 1698555, Japan. [McEnery, J. E.; Moiseev, A. A.] Univ Maryland, Dept Phys, College Pk, MD 20742 USA. [McEnery, J. E.; Moiseev, A. A.] Univ Maryland, Dept Astron, College Pk, MD 20742 USA. [Mignani, R. P.] Univ Coll London, Mullard Space Sci Lab, Dorking RH5 6NT, Surrey, England. [Moiseev, A. A.] CRESST, Greenbelt, MD 20771 USA. [Morselli, A.; Vitale, V.] Ist Nazl Fis Nucl, Sez Roma Tor Vergata, I-00133 Rome, Italy. [Norris, J. P.; Ormes, J. F.] Univ Denver, Dept Phys & Astron, Denver, CO 80208 USA. [Ohsugi, T.; Takahashi, H.] Hiroshima Univ, Hiroshima Astrophys Sci Ctr, Hiroshima 7398526, Japan. [Okumura, A.; Takahashi, T.] JAXA, Inst Space & Astronaut Sci, Chuo Ku, Kanagawa 2525210, Japan. [Orlando, E.] Max Planck Inst Extraterr Phys, D-85748 Garching, Germany. [Paneque, D.] Max Planck Inst Phys & Astrophys, D-80805 Munich, Germany. [Pohl, M.] Univ Potsdam, Inst Phys & Astron, D-14476 Potsdam, Germany. [Pohl, M.] Deutsch Elektronen Synchrotron DESY, D-15738 Zeuthen, Germany. [Reimer, O.] Leopold Franzens Univ Innsbruck, Inst Astro & Teilchenphys, A-6020 Innsbruck, Austria. [Reimer, O.] Leopold Franzens Univ Innsbruck, Inst Theoret Phys, A-6020 Innsbruck, Austria. [Roth, M.] Univ Washington, Dept Phys, Seattle, WA 98195 USA. [Tibolla, O.] Univ Wurzburg, Inst Theoret Phys & Astrophys, D-97074 Wurzburg, Germany. [Torres, D. F.] ICREA, Barcelona, Spain. [Tramacere, A.; Vianello, G.] CIFS, I-10133 Turin, Italy. [Tramacere, A.] INTEGRAL Sci Data Ctr, CH-1290 Versoix, Switzerland. [Vitale, V.] Univ Roma Tor Vergata, Dipartimento Fis, I-00133 Rome, Italy. [Yamazaki, R.] Aoyama Gakuin Univ, Dept Math & Phys, Kanagawa 2525258, Japan. RP Abdo, AA (reprint author), George Mason Univ, Coll Sci, Ctr Earth Observing & Space Res, Fairfax, VA 22030 USA. EM markusa@slac.stanford.edu; funk@slac.stanford.edu; uchiyama@slac.stanford.edu RI Johannesson, Gudlaugur/O-8741-2015; Gargano, Fabio/O-8934-2015; Loparco, Francesco/O-8847-2015; Moskalenko, Igor/A-1301-2007; Mazziotta, Mario /O-8867-2015; Sgro, Carmelo/K-3395-2016; Torres, Diego/O-9422-2016; Orlando, E/R-5594-2016; Rando, Riccardo/M-7179-2013; Hays, Elizabeth/D-3257-2012; Morselli, Aldo/G-6769-2011; Thompson, David/D-2939-2012; Harding, Alice/D-3160-2012; Gehrels, Neil/D-2971-2012; McEnery, Julie/D-6612-2012; Baldini, Luca/E-5396-2012; lubrano, pasquale/F-7269-2012; Kuss, Michael/H-8959-2012; giglietto, nicola/I-8951-2012; Reimer, Olaf/A-3117-2013; Tosti, Gino/E-9976-2013; Funk, Stefan/B-7629-2015 OI Tramacere, Andrea/0000-0002-8186-3793; Baldini, Luca/0000-0002-9785-7726; Rando, Riccardo/0000-0001-6992-818X; Bastieri, Denis/0000-0002-6954-8862; Chaty, Sylvain/0000-0002-5769-8601; Pesce-Rollins, Melissa/0000-0003-1790-8018; Giroletti, Marcello/0000-0002-8657-8852; Cutini, Sara/0000-0002-1271-2924; Berenji, Bijan/0000-0002-4551-772X; Gasparrini, Dario/0000-0002-5064-9495; Johannesson, Gudlaugur/0000-0003-1458-7036; Gargano, Fabio/0000-0002-5055-6395; Loparco, Francesco/0000-0002-1173-5673; Moskalenko, Igor/0000-0001-6141-458X; Mazziotta, Mario /0000-0001-9325-4672; Torres, Diego/0000-0002-1522-9065; Giordano, Francesco/0000-0002-8651-2394; De Angelis, Alessandro/0000-0002-3288-2517; Frailis, Marco/0000-0002-7400-2135; Caraveo, Patrizia/0000-0003-2478-8018; Sgro', Carmelo/0000-0001-5676-6214; Morselli, Aldo/0000-0002-7704-9553; Thompson, David/0000-0001-5217-9135; lubrano, pasquale/0000-0003-0221-4806; giglietto, nicola/0000-0002-9021-2888; Reimer, Olaf/0000-0001-6953-1385; Funk, Stefan/0000-0002-2012-0080 FU K. A. Wallenberg Foundation; European Community [ERC-StG-259391]; International Doctorate on Astroparticle Physics (IDAPP) program FX Royal Swedish Academy of Sciences Research Fellow, funded by a grant from the K. A. Wallenberg Foundation.; Funded by contract ERC-StG-259391 from the European Community.; Partially supported by the International Doctorate on Astroparticle Physics (IDAPP) program. NR 47 TC 134 Z9 137 U1 0 U2 10 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X J9 ASTROPHYS J JI Astrophys. J. PD JUN 10 PY 2011 VL 734 IS 1 AR 28 DI 10.1088/0004-637X/734/1/28 PG 9 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 769OS UT WOS:000291026900028 ER PT J AU Jenkins, LP Brandt, WN Colbert, EJM Koribalski, B Kuntz, KD Levan, AJ Ojha, R Roberts, TP Ward, MJ Zezas, A AF Jenkins, L. P. Brandt, W. N. Colbert, E. J. M. Koribalski, B. Kuntz, K. D. Levan, A. J. Ojha, R. Roberts, T. P. Ward, M. J. Zezas, A. TI INVESTIGATING THE NUCLEAR ACTIVITY OF BARRED SPIRAL GALAXIES: THE CASE OF NGC 1672 SO ASTROPHYSICAL JOURNAL LA English DT Article DE galaxies: evolution; galaxies: individual (NGC 1672); galaxies: nuclei; galaxies: spiral ID RADIATIVELY INEFFICIENT ACCRETION; TELESCOPE ADVANCED CAMERA; NEARBY SEYFERT-GALAXIES; XMM-NEWTON OBSERVATIONS; STAR-FORMING GALAXIES; X-RAY SUPERNOVAE; GALACTIC NUCLEI; SPACE-TELESCOPE; EMISSION-LINE; RADIO-EMISSION AB We have performed an X-ray study of the nearby barred spiral galaxy NGC 1672, primarily to ascertain the effect of the bar on its nuclear activity. We use both Chandra and XMM-Newton observations to investigate its X-ray properties, together with supporting high-resolution optical imaging data from the Hubble Space Telescope (HST), infrared imaging from the Spitzer Space Telescope, and Australia Telescope Compact Array ground-based radio data. We detect 28 X-ray sources within the D-25 area of the galaxy; many are spatially correlated with star formation in the bar and spiral arms, and two are identified as background galaxies in the HST images. Nine of the X-ray sources are ultraluminous X-ray sources, with the three brightest (L-X > 5 x 10(39) erg s(-1)) located at the ends of the bar. With the spatial resolution of Chandra, we are able to show for the first time that NGC 1672 possesses a hard (Gamma similar to 1.5) nuclear X-ray source with a 2-10 keV luminosity of 4 x 10(38) erg s(-1). This is surrounded by an X-ray-bright circumnuclear star-forming ring, comprised of point sources and hot gas, which dominates the 2-10 keV emission in the central region of the galaxy. The spatially resolved multiwavelength photometry indicates that the nuclear source is a low-luminosity active galactic nucleus (LLAGN), but with star formation activity close to the central black hole. A high-resolution multiwavelength survey is required to fully assess the impact of both large-scale bars and smaller-scale phenomena such as nuclear bars, rings, and nuclear spirals on the fueling of LLAGN. C1 [Jenkins, L. P.] NASA, Goddard Space Flight Ctr, Lab Xray Astrophys, Greenbelt, MD 20771 USA. [Jenkins, L. P.; Colbert, E. J. M.; Kuntz, K. D.] Johns Hopkins Univ, Baltimore, MD 21218 USA. [Brandt, W. N.] Penn State Univ, Dept Astron & Astrophys, University Pk, PA 16802 USA. [Brandt, W. N.] Penn State Univ, Inst Gravitat & Cosmos, University Pk, PA 16802 USA. [Koribalski, B.] CSIRO, Australia Telescope Natl Facil, Epping, NSW 1710, Australia. [Levan, A. J.] Univ Warwick, Dept Phys, Coventry CV4 7AL, W Midlands, England. [Ojha, R.] USN Observ, NVI, Washington, DC 20392 USA. [Roberts, T. P.; Ward, M. J.] Univ Durham, Dept Phys, Durham DH1 3LE, England. [Zezas, A.] Univ Crete, Dept Phys, GR-71003 Iraklion, Greece. RP Jenkins, LP (reprint author), NASA, Goddard Space Flight Ctr, Lab Xray Astrophys, Code 662, Greenbelt, MD 20771 USA. RI Zezas, Andreas/C-7543-2011; Brandt, William/N-2844-2015; OI Zezas, Andreas/0000-0001-8952-676X; Brandt, William/0000-0002-0167-2453; Jenkins, Leigh/0000-0001-9464-0719 FU NASA [NNX10AC99G, NAS8-03060, NAS 5-26555]; ESA Member States; Commonwealth of Australia FX We thank the referee for helpful comments that have improved the manuscript. L.P.J. acknowledges funding for the majority of this project from the NASA Postdoctoral Fellowship Program. W.N.B. acknowledges NASA ADP grant NNX10AC99G. This research has made use of software provided by the Chandra X-ray Center (CXC), which is operated by the Smithsonian Astrophysical Observatory for and on behalf of the National Aeronautics Space Administration under contract NAS8-03060. The XMM-Newton observatory is an ESA science mission with instruments and contributions directly funded by ESA Member States and NASA. Observations made with the NASA/ESA Hubble Space Telescope were obtained from the data archive at the Space Telescope Institute. STScI is operated by the association of Universities for Research in Astronomy, Inc. under the NASA contract NAS 5-26555. The Spitzer Space Telescope is operated by the Jet Propulsion Laboratory, California Institute of Technology under a contract with NASA. The Australia Telescope Compact Array is part of the Australia Telescope which is funded by the Commonwealth of Australia for operation as a National Facility managed by CSIRO. This research has made use of the NASA/IPAC Infrared Science Archive, which is operated by the Jet Propulsion Laboratory, California Institute of Technology, under contract with NASA. NR 99 TC 3 Z9 3 U1 0 U2 3 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X J9 ASTROPHYS J JI Astrophys. J. PD JUN 10 PY 2011 VL 734 IS 1 AR 33 DI 10.1088/0004-637X/734/1/33 PG 20 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 769OS UT WOS:000291026900033 ER PT J AU Rouillard, AP Sheeley, NR Cooper, TJ Davies, JA Lavraud, B Kilpua, EKJ Skoug, RM Steinberg, JT Szabo, A Opitz, A Sauvaud, JA AF Rouillard, A. P. Sheeley, N. R., Jr. Cooper, T. J. Davies, J. A. Lavraud, B. Kilpua, E. K. J. Skoug, R. M. Steinberg, J. T. Szabo, A. Opitz, A. Sauvaud, J. -A. TI THE SOLAR ORIGIN OF SMALL INTERPLANETARY TRANSIENTS SO ASTROPHYSICAL JOURNAL LA English DT Article DE solar wind; Sun: corona; Sun: coronal mass ejections (CMEs); Sun: heliosphere ID CORONAL MASS EJECTIONS; MAGNETIC CLOUD EXPANSION; ALFVEN WAVES; FLUX ROPE; 1 AU; HELIOSPHERIC IMAGERS; STEREO OBSERVATIONS; WIND SPACECRAFT; STREAMER BLOBS; PLASMA AB In this paper, we present evidence for magnetic transients with small radial extents ranging from 0.025 to 0.118 AU measured in situ by the Solar-Terrestrial Relations Observatory (STEREO) and the near-Earth Advanced Composition Explorer (ACE) and Wind spacecraft. The transients considered in this study are much smaller (< 0.12 AU) than the typical sizes of magnetic clouds measured near 1 AU (similar to 0.23 AU). They are marked by low plasma beta values, generally lower magnetic field variance, short timescale magnetic field rotations, and are all entrained by high-speed streams by the time they reach 1 AU. We use this entrainment to trace the origin of these small interplanetary transients in coronagraph images. We demonstrate that these magnetic field structures originate as either small or large mass ejecta. The small mass ejecta often appear from the tip of helmet streamers as arch-like structures and other poorly defined white-light features (the so-called blobs). However, we have found a case of a small magnetic transient tracing back to a small and narrow mass ejection erupting from below helmet streamers. Surprisingly, one of the small magnetic structures traces back to a large mass ejection; in this case, we show that the central axis of the coronal mass ejection is along a different latitude and longitude to that of the in situ spacecraft. The small size of the transient is related to the in situ measurements being taken on the edges or periphery of a larger magnetic structure. In the last part of the paper, an ejection with an arch-like aspect is tracked continuously to 1 AU in the STEREO images. The associated in situ signature is not that of a magnetic field rotation but rather of a temporary reversal of the magnetic field direction. Due to its "open-field topology," we speculate that this structure is partly formed near helmet streamers due to reconnection between closed and open magnetic field lines. The implications of these observations for our understanding of the variability of the slow solar wind are discussed. C1 [Rouillard, A. P.] George Mason Univ, Coll Sci, Fairfax, VA 22030 USA. [Rouillard, A. P.; Szabo, A.] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA. [Sheeley, N. R., Jr.; Cooper, T. J.] USN, Res Lab, Washington, DC USA. [Davies, J. A.] Rutherford Appleton Lab, RAL Space, Chilton OX11 0QX, England. [Lavraud, B.; Opitz, A.; Sauvaud, J. -A.] Univ Toulouse, Ctr Etud Spatiale Rayonnements, F-21028 Toulouse, France. [Lavraud, B.; Opitz, A.; Sauvaud, J. -A.] CNRS, UMR 5187, Toulouse, France. [Kilpua, E. K. J.] Univ Helsinki, Dept Phys Sci, Div Theoret Phys, FIN-00014 Helsinki, Finland. [Skoug, R. M.; Steinberg, J. T.] Los Alamos Natl Lab, Los Alamos, NM 87545 USA. RP Rouillard, AP (reprint author), George Mason Univ, Coll Sci, Fairfax, VA 22030 USA. RI Kilpua, Emilia/G-8994-2012 FU NASA [NNX11AD40G-45527, NNXIOAT06G]; Academy of Finland [130298]; Office of Naval Research FX The STEREO/SECCHI data are produced by a consortium of RAL (UK), NRL (USA), LMSAL (USA), GSFC (USA), MPS (Germany), CSL (Belgium), IOTA (France), and IAS (France). The ACE data were obtained from the ACE science center. The Wind data were obtained from the Space Physics Data Facility. The SECCHI images were obtained from the Naval Research Laboratory, Washington DC, USA, and the World Data Center, Chilton, UK. This work was partly supported by NASA. E.K. J.K.'s study was supported through the Academy of Finland (project 130298). The NRL employees acknowledge support from the Office of Naval Research. The work of A.P.R. was partly funded by NASA contracts NNX11AD40G-45527 and NNXIOAT06G. NR 70 TC 21 Z9 21 U1 0 U2 10 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X J9 ASTROPHYS J JI Astrophys. J. PD JUN 10 PY 2011 VL 734 IS 1 AR 7 DI 10.1088/0004-637X/734/1/7 PG 10 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 769OS UT WOS:000291026900007 ER PT J AU Teske, JK Najita, JR Carr, JS Pascucci, I Apai, D Henning, T AF Teske, Johanna K. Najita, Joan R. Carr, John S. Pascucci, Ilaria Apai, Daniel Henning, Thomas TI MEASURING ORGANIC MOLECULAR EMISSION IN DISKS WITH LOW-RESOLUTION SPITZER SPECTROSCOPY SO ASTROPHYSICAL JOURNAL LA English DT Article DE circumstellar matter; infrared: stars; protoplanetary disks; stars: formation; stars: pre-main sequence ID T-TAURI STARS; CO FUNDAMENTAL EMISSION; YOUNG STELLAR OBJECTS; X-RAY-EMISSION; MAIN-SEQUENCE STARS; HERBIG-AE STARS; PROTOPLANETARY DISKS; INNER-DISK; CIRCUMSTELLAR DISKS; TRANSITIONAL DISKS AB We explore the extent to which Spitzer Infrared Spectrograph (IRS) spectra taken at low spectral resolution can be used in quantitative studies of organic molecular emission from disks surrounding low-mass young stars. We use Spitzer IRS spectra taken in both the high- and low-resolution modules for the same sources to investigate whether it is possible to define line indices that can measure trends in the strength of the molecular features in low-resolution data. We find that trends in the HCN emission strength seen in the high-resolution data can be recovered in low-resolution data. In examining the factors that influence the HCN emission strength, we find that the low-resolution HCN flux is modestly correlated with stellar accretion rate and X-ray luminosity. Correlations of this kind are perhaps expected based on recent observational and theoretical studies of inner disk atmospheres. Our results demonstrate the potential of using the large number of low-resolution disk spectra that reside in the Spitzer archive to study the factors that influence the strength of molecular emission from disks. Such studies would complement results for the much smaller number of circumstellar disks that have been observed at high resolution with IRS. C1 [Teske, Johanna K.] Univ Arizona, Steward Observ, Tucson, AZ 85721 USA. [Najita, Joan R.] Natl Opt Astron Observ, Tucson, AZ 85716 USA. [Carr, John S.] USN, Res Lab, Washington, DC 20375 USA. [Pascucci, Ilaria; Apai, Daniel] Space Telescope Sci Inst, Baltimore, MD 21218 USA. [Henning, Thomas] Max Planck Inst Astron, D-69117 Heidelberg, Germany. RP Teske, JK (reprint author), Univ Arizona, Steward Observ, 933 N Cherry Ave, Tucson, AZ 85721 USA. EM jteske@as.arizona.edu; najita@noao.edu; carr@nrl.navy.mil; pascucci@stsci.edu; apai@stsci.edu; henning@mpia.de NR 77 TC 6 Z9 6 U1 0 U2 3 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0004-637X J9 ASTROPHYS J JI Astrophys. J. PD JUN 10 PY 2011 VL 734 IS 1 AR 27 DI 10.1088/0004-637X/734/1/27 PG 9 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 769OS UT WOS:000291026900027 ER PT J AU Mutus, JY Livadaru, L Robinson, JT Urban, R Salomons, MH Cloutier, M Wolkow, RA AF Mutus, J. Y. Livadaru, L. Robinson, J. T. Urban, R. Salomons, M. H. Cloutier, M. Wolkow, R. A. TI Low-energy electron point projection microscopy of suspended graphene, the ultimate 'microscope slide' SO NEW JOURNAL OF PHYSICS LA English DT Article ID MEMBRANES; IMAGES; FILMS; RIPPLES; FIBERS; SINGLE; DAMAGE; ATOMS AB Point projection microscopy (PPM) is used to image suspended graphene by using low-energy electrons (100-205 eV). Because of the low energies used, the graphene is neither damaged nor contaminated by the electron beam for doses of the order of 10(7) electrons per nm(2). The transparency of graphene is measured to be 74%, equivalent to electron transmission through a sheet twice as thick as the covalent radius of sp(2)-bonded carbon. Also observed is rippling in the structure of the suspended graphene, with a wavelength of approximately 26 nm. The interference of the electron beam due to diffraction off the edge of a graphene knife edge is observed and is used to calculate a virtual source size of 4.7 +/- 0.6 angstrom for the electron emitter. It is demonstrated that graphene can serve as both the anode and the substrate in PPM, thereby avoiding distortions due to strong field gradients around nanoscale objects. Graphene can be used to image objects suspended on the sheet using PPM and, in the future, electron holography. C1 [Mutus, J. Y.; Livadaru, L.; Urban, R.; Salomons, M. H.; Cloutier, M.; Wolkow, R. A.] Univ Alberta, Dept Phys, Edmonton, AB T6G 2G7, Canada. [Mutus, J. Y.; Livadaru, L.; Urban, R.; Salomons, M. H.; Cloutier, M.; Wolkow, R. A.] Natl Res Council Canada, Natl Inst Nanotechnol, Edmonton, AB T6G 2M9, Canada. [Robinson, J. T.] USN, Res Lab, Washington, DC 20375 USA. RP Mutus, JY (reprint author), Univ Alberta, Dept Phys, 11322-89 Ave, Edmonton, AB T6G 2G7, Canada. EM jmutus@ualberta.ca RI Robinson, Jeremy/F-2748-2010 FU Natural Sciences and Engineering Research Council (NSERC) of Canada; Alberta Innovates-Technology Futures FX We thank P E Sheehan for facilitating this research and for his help with the preparation of this paper. The authors are grateful to B Cho for fruitful discussion and encouragement. The Microscopy group at the National Institute for Nanotechnology provided facilities for imaging the graphene sample in STEM. We thank the Natural Sciences and Engineering Research Council (NSERC) of Canada and Alberta Innovates-Technology Futures for funding this research. NR 39 TC 21 Z9 21 U1 3 U2 26 PU IOP PUBLISHING LTD PI BRISTOL PA DIRAC HOUSE, TEMPLE BACK, BRISTOL BS1 6BE, ENGLAND SN 1367-2630 J9 NEW J PHYS JI New J. Phys. PD JUN 8 PY 2011 VL 13 AR 063011 DI 10.1088/1367-2630/13/6/063011 PG 11 WC Physics, Multidisciplinary SC Physics GA 784EU UT WOS:000292139000004 ER PT J AU Pechkis, JA Carini, JL Rogers, CE Gould, PL Kallush, S Kosloff, R AF Pechkis, J. A. Carini, J. L. Rogers, C. E., III Gould, P. L. Kallush, S. Kosloff, R. TI Coherent control of ultracold Rb-85 trap-loss collisions with nonlinearly frequency-chirped light SO PHYSICAL REVIEW A LA English DT Article ID LOCKED DIODE-LASER; PULSES; PHOTOASSOCIATION; MOLECULES; ATOMS; STATE AB We present results on coherent control of ultracold trap-loss collisions using 40-ns pulses of nonlinearly frequency-chirped light. The chirps, either positive or negative, sweep similar to 1 GHz in 100 ns and are centered at various detunings below the D-2 line of Rb-85. At each center detuning, we compare the collisional rate constant beta for chirps that are linear in time, concave-down, and concave-up. For positive chirps, we find that beta generally depends very little on the shape of the chirp. For negative chirps, however, we find that beta can be enhanced by up to 50(20)% for the case of the concave-down shape. This occurs at detunings where the evolution of the wave packet is expected to be coherent. An enhancement at these detunings is also seen in quantum-mechanical simulations of the collisional process. C1 [Pechkis, J. A.; Carini, J. L.; Rogers, C. E., III; Gould, P. L.] Univ Connecticut, Dept Phys, Storrs, CT 06269 USA. [Kallush, S.] ORT Braude, Dept Phys & Opt Engn, Karmiel, Israel. [Kosloff, R.] Hebrew Univ Jerusalem, Dept Phys Chem, IL-91094 Jerusalem, Israel. [Kosloff, R.] Hebrew Univ Jerusalem, Fritz Haber Res Ctr Mol Dynam, IL-91094 Jerusalem, Israel. RP Pechkis, JA (reprint author), USN, Res Lab, 4555 Overlook Ave SW, Washington, DC 20375 USA. RI Kosloff, Ronnie/D-2388-2013 OI Kosloff, Ronnie/0000-0001-6201-2523 FU Chemical Sciences, Geosciences and Biosciences Division, Office of Basic Energy Sciences, Office of Science, US Department of Energy FX The work at the University of Connecticut is supported by the Chemical Sciences, Geosciences and Biosciences Division, Office of Basic Energy Sciences, Office of Science, US Department of Energy. NR 36 TC 13 Z9 13 U1 0 U2 5 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1050-2947 J9 PHYS REV A JI Phys. Rev. A PD JUN 6 PY 2011 VL 83 IS 6 AR 063403 DI 10.1103/PhysRevA.83.063403 PG 5 WC Optics; Physics, Atomic, Molecular & Chemical SC Optics; Physics GA 773LL UT WOS:000291308700011 ER PT J AU Hui, CY Long, R Wahl, KJ Everett, RK AF Hui, Chung-Yuen Long, Rong Wahl, Kathryn J. Everett, Richard K. TI Barnacles resist removal by crack trapping SO JOURNAL OF THE ROYAL SOCIETY INTERFACE LA English DT Article DE barnacles; crack; energy release rate ID ANTIFOULING COATINGS; ADHESIVE PLAQUE; RIGID PUNCH; BALANUS; CEMENT; MECHANICS; SURFACES; POLYMERIZATION; AMPHITRITE; DETACHMENT AB We study the mechanics of pull-off of a barnacle adhering to a thin elastic layer which is bonded to a rigid substrate. We address the case of barnacles having acorn shell geometry and hard, calcarious base plates. Pull-off is initiated by the propagation of an interface edge crack between the base plate and the layer. We compute the energy release rate of this crack as it grows along the interface using a finite element method. We also develop an approximate analytical model to interpret our numerical results and to give a closed-form expression for the energy release rate. Our result shows that the resistance of barnacles to interfacial failure arises from a crack-trapping mechanism. C1 [Hui, Chung-Yuen; Long, Rong] Cornell Univ, Sibley Sch Mech & Aerosp Engn, Ithaca, NY 14853 USA. [Wahl, Kathryn J.] USN, Res Lab, Div Chem, Washington, DC 20375 USA. [Everett, Richard K.] USN, Res Lab, Div Mat Sci & Technol, Washington, DC 20375 USA. RP Hui, CY (reprint author), Cornell Univ, Sibley Sch Mech & Aerosp Engn, Ithaca, NY 14853 USA. EM ch45@cornell.edu RI Long, Rong/C-4379-2011; OI Everett, Richard/0000-0002-6725-9442; Wahl, Kathryn/0000-0001-8163-6964 FU US Department of Energy, Office of Basic Energy Science, Division of Material Sciences and Engineering [DE-FG02-07ER46463]; Office of Naval Research and the Naval Research Laboratory FX C.Y.H. and R. L. are supported by the US Department of Energy, Office of Basic Energy Science, Division of Material Sciences and Engineering under Award (DE-FG02-07ER46463). K.J.W. and R. K. E. acknowledge the support of Office of Naval Research and the Naval Research Laboratory's basic research programme. R. K. E. gratefully acknowledges the use of a high resolution Skyscan 1172 at Micro Photonics Inc. (Allentown, PA, USA). C.Y.H., R. L. and K.J.W. enjoy discussions with Anand Jagota at Lehigh University. NR 37 TC 8 Z9 8 U1 2 U2 19 PU ROYAL SOC PI LONDON PA 6-9 CARLTON HOUSE TERRACE, LONDON SW1Y 5AG, ENGLAND SN 1742-5689 J9 J R SOC INTERFACE JI J. R. Soc. Interface PD JUN 6 PY 2011 VL 8 IS 59 BP 868 EP 879 DI 10.1098/rsif.2010.0567 PG 12 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA 752EL UT WOS:000289672200010 PM 21208968 ER PT J AU Namjoshi, OA Gryboski, A Fonseca, GO Van Linn, ML Wang, ZJ Deschamps, JR Cook, JM AF Namjoshi, Ojas A. Gryboski, Angelica Fonseca, German O. Van Linn, Michael L. Wang, Zhi-jian Deschamps, Jeffrey R. Cook, James M. TI Development of a Two-Step Route to 3-PBC and beta CCt, Two Agents Active against Alcohol Self-Administration in Rodent and Primate Models SO JOURNAL OF ORGANIC CHEMISTRY LA English DT Article ID C-N; BOND FORMATION; PHARMACOPHORE; CARBAZOLES; CARBOLINES; RECEPTORS; ARYLATION; ANTAGONIST; AMINATION; CATALYSTS AB To gain access to 3-propoxy-beta-carboline hydrochloride (3-PBC center dot HCl) (1 center dot HCl) and beta-carboline-3-carboxylate-tert-butyl ester (beta CCt) (2), potential clinical agents active against alcohol self-administration, a two-step route was developed. This process involves a palladium-catalyzed Buchwald Hartwig coupling and an intramolecular Heck reaction. C1 [Namjoshi, Ojas A.; Gryboski, Angelica; Fonseca, German O.; Van Linn, Michael L.; Wang, Zhi-jian; Cook, James M.] Univ Wisconsin, Dept Chem & Biochem, Milwaukee, WI 53211 USA. [Deschamps, Jeffrey R.] USN, Res Lab, Ctr Biomol Sci & Engn, Washington, DC 20375 USA. RP Cook, JM (reprint author), Univ Wisconsin, Dept Chem & Biochem, Milwaukee, WI 53211 USA. EM capncook@uwm.edu OI Deschamps, Jeffrey/0000-0001-5845-0010; Namjoshi, Ojas/0000-0002-2142-3702 FU NIMH [MH 046851]; NIAAA [AA016179] FX We thank the NIMH (MH 046851) (J.M.C.) and NIAAA (AA016179) as well as the Lynde and Harry Bradley Foundation for generous financial support. The crystallographic analysis was carried out at the Naval Research Laboratory. NR 37 TC 7 Z9 7 U1 0 U2 4 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0022-3263 J9 J ORG CHEM JI J. Org. Chem. PD JUN 3 PY 2011 VL 76 IS 11 BP 4721 EP 4727 DI 10.1021/jo200425m PG 7 WC Chemistry, Organic SC Chemistry GA 770ZZ UT WOS:000291128300045 PM 21495660 ER PT J AU Viner, V Viner, G AF Viner, Veronika Viner, Gloria TI Effect of Filler Choice on a Binary Frontal Polymerization System SO JOURNAL OF PHYSICAL CHEMISTRY B LA English DT Article ID PROPAGATING FRONT; CONVECTION; PRODUCT AB Binary frontal polymerization is a process that involves two different systems polymerizing simultaneously but independently of each other. Various factors including filler choice and initiator concentration can affect front temperature and velocity. Like thermal frontal polymerization systems, binary frontal polymerization of a cyanate ester system and multifunctional acrylate is affected by initiator (amine) concentration and filler choice. Systems with higher viscosities and higher initiator concentrations resulted in higher velocities. Front temperature was rarely affected by filler choice. Aniline concentration and initial monomer ratios had a greater effect on front temperature than filler choice does. C1 [Viner, Veronika] USN, Naval Air Syst Command NAVAIR, Naval Air Warfare Ctr, Weap Div NAWCWD,Res Dept,Chem Div, China Lake, CA 93555 USA. [Viner, Gloria] Louisiana State Univ, Dept Chem, Baton Rouge, LA 70803 USA. RP Viner, V (reprint author), USN, Naval Air Syst Command NAVAIR, Naval Air Warfare Ctr, Weap Div NAWCWD,Res Dept,Chem Div, 1900 N Knox Rd,Stop 6303, China Lake, CA 93555 USA. EM Veronika.Viner@navy.mil FU China Lake Naval Air Warfare Center Weapons Division FX This research was funded by China Lake Naval Air Warfare Center Weapons Division. NR 20 TC 6 Z9 6 U1 1 U2 1 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1520-6106 J9 J PHYS CHEM B JI J. Phys. Chem. B PD JUN 2 PY 2011 VL 115 IS 21 BP 6862 EP 6867 DI 10.1021/jp112365a PG 6 WC Chemistry, Physical SC Chemistry GA 768EP UT WOS:000290914600007 PM 21557600 ER PT J AU Dawood, FS Ambrose, JF Russell, BP Hawksworth, AW Winchell, JM Glass, N Thurman, K Soltis, MA McDonough, E Warner, AK Weston, E Clemmons, NS Rosen, J Mitchell, SL Faix, DJ Blair, PJ Moore, MR Lowery, J AF Dawood, Fatimah S. Ambrose, John F. Russell, Bruce P. Hawksworth, Anthony W. Winchell, Jonas M. Glass, Nina Thurman, Kathleen Soltis, Michele A. McDonough, Erin Warner, Agnes K. Weston, Emily Clemmons, Nakia S. Rosen, Jennifer Mitchell, Stephanie L. Faix, Dennis J. Blair, Patrick J. Moore, Matthew R. Lowery, John TI Outbreak of Pneumonia in the Setting of Fatal Pneumococcal Meningitis among US Army Trainees: Potential Role of Chlamydia pneumoniae Infection SO BMC INFECTIOUS DISEASES LA English DT Article DE Pneumonia; pneumococcal; Chlamydophila; pneumoniae; Military Personnel ID REAL-TIME PCR; STREPTOCOCCUS-PNEUMONIAE; MYCOPLASMA-PNEUMONIAE; MILITARY PERSONNEL; EPIDEMIC; FINLAND; COMMUNITY AB Background: Compared to the civilian population, military trainees are often at increased risk for respiratory infections. We investigated an outbreak of radiologically-confirmed pneumonia that was recognized after 2 fatal cases of serotype 7F pneumococcal meningitis were reported in a 303-person military trainee company (Alpha Company). Methods: We reviewed surveillance data on pneumonia and febrile respiratory illness at the training facility; conducted chart reviews for cases of radiologically-confirmed pneumonia; and administered surveys and collected nasopharyngeal swabs from trainees in the outbreak battalion (Alpha and Hotel Companies), associated training staff, and trainees newly joining the battalion. Results: Among Alpha and Hotel Company trainees, the average weekly attack rates of radiologically-confirmed pneumonia were 1.4% and 1.2% (most other companies at FLW: 0-0.4%). The pneumococcal carriage rate among all Alpha Company trainees was 15% with a predominance of serotypes 7F and 3. Chlamydia pneumoniae was identified from 31% of specimens collected from Alpha Company trainees with respiratory symptoms. Conclusion: Although the etiology of the outbreak remains unclear, the identification of both S. pneumoniae and C. pneumoniae among trainees suggests that both pathogens may have contributed either independently or as cofactors to the observed increased incidence of pneumonia in the outbreak battalion and should be considered as possible etiologies in outbreaks of pneumonia in the military population. C1 [Dawood, Fatimah S.] Ctr Dis Control & Prevent, Epidem Intelligence Serv, Off Workforce & Career Dev, Influenza Epidemiol & Prevent Branch,Influenza Di, Atlanta, GA 30333 USA. [Winchell, Jonas M.; Glass, Nina; Thurman, Kathleen; Warner, Agnes K.; Weston, Emily; Rosen, Jennifer; Mitchell, Stephanie L.; Moore, Matthew R.] Ctr Dis Control & Prevent, Resp Dis Branch, Div Bacterial Dis, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA. [Ambrose, John F.; Soltis, Michele A.; Clemmons, Nakia S.] USA, Ctr Hlth Promot & Prevent Med, Aberdeen Proving Ground, MD 21010 USA. [Russell, Bruce P.] Gen Leonard Wood Army Community Hosp, Div Prevent Med, Ft Leonard Wood, MO 65473 USA. [Hawksworth, Anthony W.; McDonough, Erin; Faix, Dennis J.; Blair, Patrick J.] USN, Hlth Res Ctr, San Diego, CA 92106 USA. RP Dawood, FS (reprint author), Ctr Dis Control & Prevent, Epidem Intelligence Serv, Off Workforce & Career Dev, Influenza Epidemiol & Prevent Branch,Influenza Di, 1600 Clifton Rd NE, Atlanta, GA 30333 USA. EM fdawood@cdc.gov; zdn4@cdc.gov RI Valle, Ruben/A-7512-2013; OI Glass, Nina/0000-0002-6821-4289 NR 19 TC 11 Z9 11 U1 0 U2 0 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1471-2334 J9 BMC INFECT DIS JI BMC Infect. Dis. PD JUN 2 PY 2011 VL 11 AR 157 DI 10.1186/1471-2334-11-157 PG 9 WC Infectious Diseases SC Infectious Diseases GA 783KN UT WOS:000292081300001 PM 21635754 ER PT J AU Ancona, MG AF Ancona, M. G. TI Density-gradient theory: a macroscopic approach to quantum confinement and tunneling in semiconductor devices SO JOURNAL OF COMPUTATIONAL ELECTRONICS LA English DT Article DE Continuum; Density-gradient; Electron transport; Semiconductor device simulation; Quantum confinement; Quantum tunneling; Thermodynamics ID INHOMOGENEOUS ELECTRON-GAS; DRIFT-DIFFUSION MODEL; EQUATION-OF-STATE; MOMENT EQUATIONS; INVERSION-LAYER; SIMULATION; TRANSPORT AB Density-gradient theory provides a macroscopic approach to modeling quantum transport that is particularly well adapted to semiconductor device analysis and engineering. After some introductory observations, the basis of the theory in macroscopic and microscopic physics is summarized, and its scattering-dominated and scattering-free versions are introduced. Remarks are also given about the underlying mathematics and numerics. A variety of applications of the theory to both quantum confinement and quantum tunneling situations are then reviewed. In doing so, particular emphasis is put on understanding the range of validity of the theory and on its unexpected power as a phenomenology. The article closes with a few comments about the future. C1 USN, Res Lab, Washington, DC 20375 USA. RP Ancona, MG (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM ancona@estd.nrl.navy.mil FU Office of Naval Research FX The author thanks Professor Zhiping Yu of Tsinghua University for his encouragement over many years, as well as for his kind invitation to write this article. Thanks also go to Dr. Andrew Brown of the University of Glasgow for generously allowing the use of Figs. 3.5.5-3.5.7 from [42], and to Dr. Chagaan Baatar and the Office of Naval Research for funding support. Lastly, with respect and gratitude, the author again acknowledges his teacher, the late Professor Harry F. Tiersten of the Rensselaer Polytechnic Institute, whose deep physical insight and uncompromising devotion to truth and clarity have long been an inspiration. NR 51 TC 21 Z9 21 U1 2 U2 7 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1569-8025 J9 J COMPUT ELECTRON JI J. Comput. Electron. PD JUN PY 2011 VL 10 IS 1-2 BP 65 EP 97 DI 10.1007/s10825-011-0356-9 PG 33 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA 898IM UT WOS:000300735800007 ER PT J AU Arnaud, F McCarron, R Freilich, D AF Arnaud, Francoise McCarron, Richard Freilich, Daniel TI Amylase and Lipase Detection in Hemorrhaged Animals Treated with HBOC-201 SO ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY LA English DT Article DE interference; HBOC; trauma; hemorrhage; pancreas; clinical chemistry ID BOVINE POLYMERIZED HEMOGLOBIN; CROSS-LINKED HEMOGLOBIN; TRAUMATIC BRAIN-INJURY; OXYGEN CARRIER; ENDOTHELIAL LIPASE; DEFINITIVE CARE; SERUM AMYLASE; SWINE MODEL; RESUSCITATION; PANCREATITIS AB HBOC-201 may alter lipase and amylase detection on chemistry analyzers using optical methods and affect pancreatic function after trauma. Amylase and lipase measurements were correlated against HBOC-201 to evaluate interference on samples spiked with 0-6g/dL HBOC-201. The detection threshold was 2.5g/dL or none when measured, respectively, on Vitros 250 or Advia 1650 instruments. Amylase and lipase from blood samples collected from 55% EBV hemorrhaged Yucatan min-pigs showed peaks around 24-48 hours. Amylase increase was not significant between treatments but lipase was higher in HBOC-201-treated animals. Animals particularly affected by the injury had elevated enzymes after hemorrhagic shock, without significant clinical consequences. C1 [Arnaud, Francoise; McCarron, Richard; Freilich, Daniel] USN, Med Res Ctr, Silver Spring, MD 20910 USA. [Arnaud, Francoise; McCarron, Richard; Freilich, Daniel] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA. RP Arnaud, F (reprint author), USN, Med Res Ctr, 503 Robert Grant Ave, Silver Spring, MD 20910 USA. EM francoise.arnaud@MED.NAVY.MIL FU ONR Work Unit [602236N.4426.W26.A0241] FX This work was funded from ONR Work Unit No. 602236N.4426.W26.A0241. NR 24 TC 0 Z9 0 U1 0 U2 0 PU INFORMA HEALTHCARE PI LONDON PA TELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLAND SN 1073-1199 J9 ARTIF CELL BLOOD SUB JI Artif. Cells Blood Substit. Biotechnol. PD JUN PY 2011 VL 39 IS 3 BP 155 EP 161 DI 10.3109/10731199.2010.516260 PG 7 WC Biotechnology & Applied Microbiology; Engineering, Biomedical; Materials Science, Biomaterials SC Biotechnology & Applied Microbiology; Engineering; Materials Science GA 764ZC UT WOS:000290672200007 PM 21171938 ER PT J AU Lee, DJ Andersson, K AF Lee, Deok-Jin Andersson, Klas TI Hybrid Control of Long-Endurance Aerial Robotic Vehicles for Wireless Sensor Networks SO INTERNATIONAL JOURNAL OF ADVANCED ROBOTIC SYSTEMS LA English DT Article DE Sensor networks; Autonomous aerial robot; Soaring control; Self-tuning control; Long endurance flight control ID DESIGN AB This paper presents an effective hybrid control approach for building stable wireless sensor networks between heterogeneous unmanned vehicles using long-endurance aerial robotic vehicles. For optimal deployment of the aerial vehicles in communication networks, a gradient climbing based self-estimating control algorithm is utilized to locate the aerial platforms to maintain maximum communication throughputs between distributed multiple nodes. The autonomous aerial robots, which function as communication relay nodes, extract and harvest thermal energy from the atmospheric environment to improve their flight endurance within specified communication coverage areas. The rapidly-deployable sensor networks with the high-endurance aerial vehicles can be used for various application areas including environment monitoring, surveillance, tracking, and decision-making support. Flight test and simulation studies are conducted to evaluate the effectiveness of the proposed hybrid control technique for robust communication networks. C1 [Lee, Deok-Jin; Andersson, Klas] USN, Postgrad Sch, Ctr Autonomous Vehicle Res, Monterey, CA 93943 USA. RP Lee, DJ (reprint author), USN, Postgrad Sch, Ctr Autonomous Vehicle Res, Monterey, CA 93943 USA. FU National Research Foundation; Ministry of Education, Science and Technology [NRF-2010-0026391] FX This work was supported by Mid-career Research Program through the National Research Foundation grant funded by the Ministry of Education, Science and Technology (NRF-2010-0026391). The author would like to thank to Prof. Kil-To Jung for his valuable support and advice for this research. NR 28 TC 5 Z9 5 U1 0 U2 4 PU INTECH -OPEN ACCESS PUBLISHER PI RIJEKA PA UNIV CAMPUS STEP RI, SLAVKA KRAUTZEKA 83/A, RIJEKA, 51000, CROATIA SN 1729-8806 J9 INT J ADV ROBOT SYST JI Int. J. Adv. Robot. Syst. PD JUN PY 2011 VL 8 IS 2 BP 101 EP 113 PG 13 WC Robotics SC Robotics GA 837IG UT WOS:000296187400010 ER PT J AU Livingston, MA Ai, ZM Karsch, K Gibson, GO AF Livingston, Mark A. Ai, Zhuming Karsch, Kevin Gibson, Gregory O. TI User interface design for military AR applications SO VIRTUAL REALITY LA English DT Article DE Augmented reality; Mobile systems; User interface; Interaction; Evaluation ID MOBILE AUGMENTED REALITY AB Designing a user interface for military situation awareness presents challenges for managing information in a useful and usable manner. We present an integrated set of functions for the presentation of and interaction with information for a mobile augmented reality application for military applications. Our research has concentrated on four areas. We filter information based on relevance to the user (in turn based on location), evaluate methods for presenting information that represents entities occluded from the user's view, enable interaction through a top-down map view metaphor akin to current techniques used in the military, and facilitate collaboration with other mobile users and/or a command center. In addition, we refined the user interface architecture to conform to requirements from subject matter experts. We discuss the lessons learned in our work and directions for future research. C1 [Livingston, Mark A.; Ai, Zhuming; Karsch, Kevin; Gibson, Gregory O.] USN, Res Lab, Washington, DC 20375 USA. RP Livingston, MA (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM mark.livingston@nrl.navy.mil FU NRL; DARPA [FA8650-09-C-7908] FX This work was supported in part by the NRL Base Program and in part by DARPA under the ULTRA-Vis Program for work as a performing member of the Lockheed Martin team, contract # FA8650-09-C-7908. NR 20 TC 10 Z9 10 U1 3 U2 25 PU SPRINGER LONDON LTD PI LONDON PA 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND SN 1359-4338 J9 VIRTUAL REAL-LONDON JI Virtual Real. PD JUN PY 2011 VL 15 IS 2-3 SI SI BP 175 EP 184 DI 10.1007/s10055-010-0179-1 PG 10 WC Computer Science, Interdisciplinary Applications; Computer Science, Software Engineering; Imaging Science & Photographic Technology SC Computer Science; Imaging Science & Photographic Technology GA 838IB UT WOS:000296280200008 ER PT J AU Guarda, S AF Guarda, Sylvain TI Fontane as a Biograph SO GERMAN QUARTERLY LA German DT Book Review C1 [Guarda, Sylvain] USN Acad, Annapolis, MD 21402 USA. RP Guarda, S (reprint author), USN Acad, Annapolis, MD 21402 USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 0016-8831 J9 GER QUART JI Ger. Q. PD SUM PY 2011 VL 84 IS 3 BP 370 EP 371 PG 2 WC Language & Linguistics; Literature, German, Dutch, Scandinavian SC Linguistics; Literature GA 805AB UT WOS:000293697300009 ER PT J AU Reid, JS Benedetti, A Colarco, PR Hansen, JA AF Reid, Jeffrey S. Benedetti, Angela Colarco, Peter R. Hansen, James A. TI INTERNATIONAL OPERATIONAL AEROSOL OBSERVABILITY WORKSHOP SO BULLETIN OF THE AMERICAN METEOROLOGICAL SOCIETY LA English DT Editorial Material C1 [Reid, Jeffrey S.; Hansen, James A.] USN, Marine Meteorol Div, Res Lab, Monterey, CA 93943 USA. [Benedetti, Angela] European Ctr Medium Range Weather Forecasts, Reading RG2 9AX, Berks, England. [Colarco, Peter R.] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA. RP Reid, JS (reprint author), USN, Marine Meteorol Div, Res Lab, Monterey, CA 93943 USA. EM jeffrey.reid@nrlmry.navy.mil RI Reid, Jeffrey/B-7633-2014; Colarco, Peter/D-8637-2012 OI Reid, Jeffrey/0000-0002-5147-7955; Colarco, Peter/0000-0003-3525-1662 NR 0 TC 10 Z9 10 U1 0 U2 4 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 USA SN 0003-0007 J9 B AM METEOROL SOC JI Bull. Amer. Meteorol. Soc. PD JUN PY 2011 VL 92 IS 6 BP ES21 EP ES24 DI 10.1175/2010BAMS3183.1 PG 4 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA 797MU UT WOS:000293132800001 ER PT J AU Keith, MJ Johnston, S Ray, PS Ferrara, EC Parkinson, PMS Celik, O Belfiore, A Donato, D Cheung, CC Abdo, AA Camilo, F Freire, PCC Guillemot, L Harding, AK Kramer, M Michelson, PF Ransom, SM Romani, RW Smith, DA Thompson, DJ Weltevrede, P Wood, KS AF Keith, M. J. Johnston, S. Ray, P. S. Ferrara, E. C. Parkinson, P. M. Saz Celik, O. Belfiore, A. Donato, D. Cheung, C. C. Abdo, A. A. Camilo, F. Freire, P. C. C. Guillemot, L. Harding, A. K. Kramer, M. Michelson, P. F. Ransom, S. M. Romani, R. W. Smith, D. A. Thompson, D. J. Weltevrede, P. Wood, K. S. TI Discovery of millisecond pulsars in radio searches of southern Fermi Large Area Telescope sources SO MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY LA English DT Article DE pulsars: general; pulsars: individual: J2241-5236 ID GAMMA-RAY PULSARS; BLIND FREQUENCY SEARCHES; SOURCE CATALOG; LAT; POPULATION; SYSTEM AB Using the Parkes Radio Telescope, we have carried out deep observations of 11 unassociated gamma-ray sources. Periodicity searches of these data have discovered two millisecond pulsars, PSR J1103-5403 (1FGL J1103.9-5355) and PSR J2241-5236 (1FGL J2241.9-5236), and a long-period pulsar, PSR J1604-44 (1FGL J1604.7-4443). In addition, we searched for but did not detect any radio pulsations from six gamma-ray pulsars discovered by the Fermi satellite to a level of similar to 0.04 mJy (for pulsars with a 10 per cent duty cycle). The timing of the millisecond pulsar PSR J1103-5403 has shown that its position is 9 arcmin from the centroid of the gamma-ray source. Since these observations were carried out, independent evidence has shown that 1FGL J1103.9-5355 is associated with the flat spectrum radio sourcePKS 1101-536. It appears certain that the pulsar is not associated with the gamma-ray source, despite the seemingly low probability of a chance detection of a radio millisecond pulsar. We consider that PSR J1604-44 is a chance discovery of a weak, long-period pulsar and is unlikely to be associated with 1FGL J1604.7-4443. PSR J2241-5236 has a spin period of 2.2 ms and orbits a very low mass companion with a 3.5-h orbital period. The relatively high flux density and low dispersion measure of PSR J2241-5236 make it an excellent candidate for high precision timing experiments. The gamma rays of 1FGL J2241.9-5236 have a spectrum that is well modelled by a power law with an exponential cut-off, and phase binning with the radio ephemeris results in a multipeaked gamma-ray pulse profile. Observations with Chandra have identified a coincident X-ray source within 0.1 arcsec of the position of the pulsar obtained by radio timing. C1 [Keith, M. J.; Johnston, S.] CSIRO, Australia Telescope Natl Facil, Epping, NSW 1710, Australia. [Ray, P. S.; Wood, K. S.] USN, Div Space Sci, Res Lab, Washington, DC 20375 USA. [Ferrara, E. C.; Celik, O.; Donato, D.; Kramer, M.; Thompson, D. J.] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA. [Parkinson, P. M. Saz; Belfiore, A.] Univ Calif Santa Cruz, Santa Cruz Inst Particle Phys, Dept Phys, Santa Cruz, CA 95064 USA. [Parkinson, P. M. Saz; Belfiore, A.] Univ Calif Santa Cruz, Dept Astron & Astrophys, Santa Cruz, CA 95064 USA. [Celik, O.; Donato, D.] CRESST, Greenbelt, MD 20771 USA. [Celik, O.] Univ Maryland Baltimore Cty, Dept Phys, Baltimore, MD 21250 USA. [Celik, O.] Univ Maryland Baltimore Cty, Ctr Space Sci & Technol, Baltimore, MD 21250 USA. [Belfiore, A.] INAF Ist Astrofis Spaziale Fis Cosm, I-20133 Milan, Italy. [Belfiore, A.] Univ Pavia, DFNT, I-27100 Pavia, Italy. [Donato, D.] Univ Maryland, Dept Phys, College Pk, MD 20742 USA. [Donato, D.] Univ Maryland, Dept Astron, College Pk, MD 20742 USA. [Cheung, C. C.; Abdo, A. A.] Natl Acad Sci, Natl Res Council Res Associate, Washington, DC 20001 USA. [Camilo, F.] Columbia Univ, Columbia Astrophys Lab, New York, NY 10027 USA. [Freire, P. C. C.; Guillemot, L.; Kramer, M.] Max Planck Inst Radioastron, D-53121 Bonn, Germany. [Kramer, M.; Weltevrede, P.] Univ Manchester, Jodrell Bank Ctr Astrophys, Sch Phys & Astron, Manchester M13 9PL, Lancs, England. [Michelson, P. F.; Romani, R. W.] Stanford Univ, WW Hansen Expt Phys Lab, Kavli Inst Particle Astrophys & Cosmol, Dept Phys, Stanford, CA 94305 USA. [Michelson, P. F.; Romani, R. W.] Stanford Univ, SLAC Natl Accelerator Lab, Stanford, CA 94305 USA. [Ransom, S. M.] NRAO, Charlottesville, VA 22903 USA. [Smith, D. A.] Univ Bordeaux 1, Ctr Etud Nucl Bordeaux Gradignan, CNRS, IN2p3, F-33175 Gradignan, France. RP Keith, MJ (reprint author), CSIRO, Australia Telescope Natl Facil, Epping, NSW 1710, Australia. EM mkeith@pulsarastronomy.net RI Thompson, David/D-2939-2012; Harding, Alice/D-3160-2012; Saz Parkinson, Pablo Miguel/I-7980-2013; OI Ray, Paul/0000-0002-5297-5278; Thompson, David/0000-0001-5217-9135; Ransom, Scott/0000-0001-5799-9714 FU Commonwealth of Australia; National Aeronautics and Space Administration; Department of Energy in the United States; Commissariat a l'Energie Atomique; Centre National de la Recherche Scientifique/Institut National de Physique Nucleaire et de Physique des Particules in France; Agenzia Spaziale Italiana; Istituto Nazionale di Fisica Nucleare in Italy; Ministry of Education, Culture, Sports, Science and Technology (MEXT); High Energy Accelerator Research Organization (KEK); Japan Aerospace Exploration Agency (JAXA) in Japan; K. A. Wallenberg Foundation; Swedish Research Council; Swedish National Space Board in Sweden; Istituto Nazionale di Astrofisica in Italy; Centre National d'Etudes Spatiales in France FX The Parkes Observatory is part of the Australia Telescope which is funded by the Commonwealth of Australia for operation as a National Facility managed by CSIRO.; The Fermi LAT Collaboration acknowledges generous ongoing support from a number of agencies and institutes that have supported both the development and the operation of the LAT and scientific data analysis. These include the National Aeronautics and Space Administration and the Department of Energy in the United States, the Commissariat a l'Energie Atomique and the Centre National de la Recherche Scientifique/Institut National de Physique Nucleaire et de Physique des Particules in France, the Agenzia Spaziale Italiana and the Istituto Nazionale di Fisica Nucleare in Italy, the Ministry of Education, Culture, Sports, Science and Technology (MEXT), High Energy Accelerator Research Organization (KEK) and Japan Aerospace Exploration Agency (JAXA) in Japan, and the K. A. Wallenberg Foundation, the Swedish Research Council and the Swedish National Space Board in Sweden.; Additional support for science analysis during the operations phase is gratefully acknowledged from the Istituto Nazionale di Astrofisica in Italy and the Centre National d'Etudes Spatiales in France. NR 33 TC 46 Z9 46 U1 0 U2 0 PU OXFORD UNIV PRESS PI OXFORD PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND SN 0035-8711 EI 1365-2966 J9 MON NOT R ASTRON SOC JI Mon. Not. Roy. Astron. Soc. PD JUN PY 2011 VL 414 IS 2 BP 1292 EP 1300 DI 10.1111/j.1365-2966.2011.18464.x PG 9 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 792JS UT WOS:000292740500036 ER PT J AU Geva, A Brigger, MT AF Geva, Alon Brigger, Matthew T. TI Dexamethasone and Tonsillectomy Bleeding: A Meta-Analysis SO OTOLARYNGOLOGY-HEAD AND NECK SURGERY LA English DT Review DE tonsillectomy; hemorrhage; dexamethasone; steroids ID PEDIATRIC TONSILLECTOMY; POSTOPERATIVE NAUSEA; RANDOMIZED-TRIAL; STEROID-THERAPY; CHILDREN; PAIN; ADENOTONSILLECTOMY; MANAGEMENT; ADULTS; ELECTROCAUTERY AB Objective. To use meta-analytic techniques to examine the effect of dexamethasone on the risk of postoperative bleeding following tonsillectomy. Data Sources. PubMed and Embase databases accessed on April 23, 2009, and April 28, 2009. Review Methods. Using principles of meta-analysis, inclusion and exclusion criteria were developed to identify all randomized controlled trials of patients undergoing tonsillectomy in which perioperative intravenous dexamethasone was administered in at least 1 treatment arm and bleeding complications were reported. Electronic databases were searched to identify candidate articles. Two authors independently abstracted data from each article. Discrepancies were resolved by consensus. A fixed-effects model was used to pool relative risks among studies using the Mantel-Haenszel method. Studies were assessed for publication bias using a funnel plot of studies' effect size vs standard error of the effect size as well as Begg test and Egger test. A P value <.05 was considered significant. Results. The primary search identified 85 potential studies. Fourteen met inclusion criteria and were selected for meta-analysis. No significant heterogeneity was found among studies (I(2) < 0.1%; 95% confidence interval [CI], 0%-55%; P = .68). The pooled relative risk (RR) of postoperative bleeding did not differ significantly between patients receiving dexamethasone and controls (RR, 1.02; 95% CI, 0.65-1.61; P = .92). When studies were stratified by age, primary vs secondary hemorrhage, and follow-up duration, no further significant differences in bleeding rate were identified. No evidence of publication bias was found using Begg (P = .70) or Egger (P = .73) tests. Conclusion. The results of this meta-analysis indicate that perioperative dexamethasone does not confer an increased risk of postoperative bleeding in patients undergoing tonsillectomy. C1 [Brigger, Matthew T.] USN, Dept Otolaryngol Head & Neck Surg, San Diego Med Ctr, San Diego, CA 92134 USA. [Geva, Alon] Harvard Univ, Sch Med, Dept Pediat, Boston, MA 02115 USA. [Geva, Alon] Childrens Hosp Boston, Dept Med, Boston, MA USA. RP Brigger, MT (reprint author), USN, Dept Otolaryngol Head & Neck Surg, San Diego Med Ctr, 34800 Bob Wilson Dr, San Diego, CA 92134 USA. EM matt.brigger@alumni.vanderbilt.edu NR 27 TC 12 Z9 12 U1 1 U2 6 PU SAGE PUBLICATIONS LTD PI LONDON PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND SN 0194-5998 J9 OTOLARYNG HEAD NECK JI Otolaryngol. Head Neck Surg. PD JUN PY 2011 VL 144 IS 6 BP 838 EP 843 DI 10.1177/0194599811399538 PG 6 WC Otorhinolaryngology; Surgery SC Otorhinolaryngology; Surgery GA 808SN UT WOS:000293998800002 PM 21493330 ER PT J AU Mullin, DP Ge, XX Jackson, RL Liu, JZ Pfannenstiel, TJ Balough, BJ AF Mullin, David P. Ge, Xianxi Jackson, Ron L. Liu, Jianzhong Pfannenstiel, Travis J. Balough, Ben J. TI Effects of Tympanomeatal Blunting on Sound Transfer Function SO OTOLARYNGOLOGY-HEAD AND NECK SURGERY LA English DT Article DE anterior tympanomeatal angle; blunting; laser Doppler vibrometer; round window membrane ID GRAFT TYMPANOPLASTY; ANTERIOR; RECONSTRUCTION; MYRINGOPLASTY; PERFORATION; ANGLE AB Objective. (1) To measure the peak-to-peak displacement of the round window membrane (RWM) prior to blunting procedure. (2) To evaluate the impact of blunting the anterior tympanomeatal angle (ATA) on middle ear sound transfer function. Study Design. Basic science study. Setting. Cadaveric temporal bone research laboratory. Subjects and Methods. Six fresh human temporal bones were prepared using a mastoidectomy and facial recess approach. Baseline RWM peak-to-peak displacements were obtained by single-point laser Doppler vibrometry (LDV) at 90-dB sound pressure level over a spectrum of 250 to 8000 Hz. Temporalis muscle was harvested and then fashioned into a graft for each temporal bone, mimicking ATA blunting. RWM displacement responses with the blunted ATA were measured using the LDV to judge the impact on middle ear transfer function. Results. For each of the 6 temporal bones, the average displacement decreased across all sound frequencies with the ATA blunting when compared with baseline (no blunting). Baseline velocity measurements for all sound signals averaged 4.5 x 10(-3) +/- 1.892 x 10(-3) (mean +/- SEM) mm/s, while measurements averaged 2.2 +/- 6.62 x 10(-4) mm/s with blunting of the ATA (P < .001). This amounted to a 52% decrease in velocity of the RWM following blunting of the ATA. Conclusion. Blunting of the ATA decreases the sound transfer function of the tympanic membrane and middle ear. Prevention of blunting at the ATA during tympanoplasty should be emphasized. C1 [Mullin, David P.; Ge, Xianxi; Jackson, Ron L.; Liu, Jianzhong; Pfannenstiel, Travis J.; Balough, Ben J.] USN, Dept Otolaryngol, San Diego Med Ctr, San Diego, CA 92134 USA. RP Mullin, DP (reprint author), USN, Dept Otolaryngol, Med Ctr, 34520 Bob Wilson Dr,Suite 200, San Diego, CA 92134 USA. EM david.mullin@med.navy.mil FU Chief BUMED, Navy Department, Washington, DC [S-00-005, NSHSBETHINST 6000.41B] FX The Chief BUMED, Navy Department, Washington, DC, Clinical Investigation Program sponsored this report (CIP# S-00-005) as required by NSHSBETHINST 6000.41B. NR 19 TC 1 Z9 1 U1 0 U2 3 PU SAGE PUBLICATIONS LTD PI LONDON PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND SN 0194-5998 J9 OTOLARYNG HEAD NECK JI Otolaryngol. Head Neck Surg. PD JUN PY 2011 VL 144 IS 6 BP 940 EP 944 DI 10.1177/0194599810397749 PG 5 WC Otorhinolaryngology; Surgery SC Otorhinolaryngology; Surgery GA 808SN UT WOS:000293998800021 PM 21493348 ER PT J AU Abdo, AA Ackermann, M Ajello, M Allafort, A Baldini, L Ballet, J Barbiellini, G Bastieri, D Bellazzini, R Berenji, B Blandford, RD Bloom, ED Bonamente, E Borgland, AW Bouvier, A Bregeon, J Brigida, M Bruel, P Buehler, R Buson, S Caliandro, GA Cameron, RA Caraveo, PA Casandjian, JM Cavazzuti, E Cecchi, C Charles, E Chekhtman, A Cheung, CC Chiang, J Ciprini, S Claus, R Conrad, J Cutini, S D'Ammando, F de Angelis, A de Palma, F Dermer, CD Digel, SW Silva, EDE Drell, PS Dubois, R Dumora, D Escande, L Favuzzi, C Fegan, SJ Ferrara, EC Fortin, P Fukazawa, Y Fusco, P Gargano, F Gasparrini, D Gehrels, N Germani, S Giglietto, N Giommi, P Giordano, F Giroletti, M Glanzman, T Godfrey, G Grenier, IA Grove, JE Guiriec, S Hadasch, D Hayashida, M Hays, E Horan, D Itoh, R Johannesson, G Johnson, AS Kamae, T Katagiri, H Kataoka, J Knodlseder, J Kuss, M Lande, J Larsson, S Latronico, L Lee, SH Longo, F Loparco, F Lott, B Lovellette, MN Lubrano, P Madejski, GM Makeev, A Mazziotta, MN McConville, W McEnery, JE Michelson, PF Mitthumsiri, W Mizuno, T Moiseev, AA Monte, C Monzani, ME Morselli, A Moskalenko, IV Murgia, S Naumann-Godo, M Nishino, S Nolan, PL Norris, JP Nuss, E Ohsugi, T Okumura, A Orlando, E Ormes, JF Paneque, D Pelassa, V Pesce-Rollins, M Pierbattista, M Piron, F Porter, TA Raino, S Rando, R Razzaque, S Reimer, A Reimer, O Ritz, S Roth, M Sadrozinski, HFW Sanchez, D Scargle, JD Schalk, TL Sgro, C Siskind, EJ Smith, PD Spandre, G Spinelli, P Strickman, MS Takahashi, H Takahashi, T Tanaka, T Tanaka, Y Thayer, JG Thayer, JB Thompson, DJ Tibaldo, L Torres, DF Tosti, G Tramacere, A Troja, E Vandenbroucke, J Vasileiou, V Vianello, G Vilchez, N Vitale, V Waite, AP Wang, P Winer, BL Wood, KS Yang, Z Ziegler, M AF Abdo, A. A. Ackermann, M. Ajello, M. Allafort, A. Baldini, L. Ballet, J. Barbiellini, G. Bastieri, D. Bellazzini, R. Berenji, B. Blandford, R. D. Bloom, E. D. Bonamente, E. Borgland, A. W. Bouvier, A. Bregeon, J. Brigida, M. Bruel, P. Buehler, R. Buson, S. Caliandro, G. A. Cameron, R. A. Caraveo, P. A. Casandjian, J. M. Cavazzuti, E. Cecchi, C. Charles, E. Chekhtman, A. Cheung, C. C. Chiang, J. Ciprini, S. Claus, R. Conrad, J. Cutini, S. D'Ammando, F. de Angelis, A. de Palma, F. Dermer, C. D. Digel, S. W. do Couto e Silva, E. Drell, P. S. Dubois, R. Dumora, D. Escande, L. Favuzzi, C. Fegan, S. J. Ferrara, E. C. Fortin, P. Fukazawa, Y. Fusco, P. Gargano, F. Gasparrini, D. Gehrels, N. Germani, S. Giglietto, N. Giommi, P. Giordano, F. Giroletti, M. Glanzman, T. Godfrey, G. Grenier, I. A. Grove, J. E. Guiriec, S. Hadasch, D. Hayashida, M. Hays, E. Horan, D. Itoh, R. Johannesson, G. Johnson, A. S. Kamae, T. Katagiri, H. Kataoka, J. Knoedlseder, J. Kuss, M. Lande, J. Larsson, S. Latronico, L. Lee, S. -H. Longo, F. Loparco, F. Lott, B. Lovellette, M. N. Lubrano, P. Madejski, G. M. Makeev, A. Mazziotta, M. N. McConville, W. McEnery, J. E. Michelson, P. F. Mitthumsiri, W. Mizuno, T. Moiseev, A. A. Monte, C. Monzani, M. E. Morselli, A. Moskalenko, I. V. Murgia, S. Naumann-Godo, M. Nishino, S. Nolan, P. L. Norris, J. P. Nuss, E. Ohsugi, T. Okumura, A. Orlando, E. Ormes, J. F. Paneque, D. Pelassa, V. Pesce-Rollins, M. Pierbattista, M. Piron, F. Porter, T. A. Raino, S. Rando, R. Razzaque, S. Reimer, A. Reimer, O. Ritz, S. Roth, M. Sadrozinski, H. F. -W. Sanchez, D. Scargle, J. D. Schalk, T. L. Sgro, C. Siskind, E. J. Smith, P. D. Spandre, G. Spinelli, P. Strickman, M. S. Takahashi, H. Takahashi, T. Tanaka, T. Tanaka, Y. Thayer, J. G. Thayer, J. B. Thompson, D. J. Tibaldo, L. Torres, D. F. Tosti, G. Tramacere, A. Troja, E. Vandenbroucke, J. Vasileiou, V. Vianello, G. Vilchez, N. Vitale, V. Waite, A. P. Wang, P. Winer, B. L. Wood, K. S. Yang, Z. Ziegler, M. TI FERMI GAMMA-RAY SPACE TELESCOPE OBSERVATIONS OF THE GAMMA-RAY OUTBURST FROM 3C454.3 IN NOVEMBER 2010 SO ASTROPHYSICAL JOURNAL LETTERS LA English DT Article DE galaxies: active ID ACTIVE GALACTIC NUCLEI; LARGE-AREA TELESCOPE; BLAZAR 3C 454.3; DETECTED BLAZARS; VARIABILITY; QUASARS; FLARE; CATALOG; MASSES AB The flat-spectrum radio quasar 3C454.3 underwent an extraordinary 5 day gamma-ray outburst in 2010 November when the daily flux measured with the Fermi Large Area Telescope (LAT) at photon energies E > 100 MeV reached (66 +/- 2) x 10(-6) photons cm(-2) s(-1). This is a factor of three higher than its previous maximum flux recorded in 2009 December and greater than or similar to 5 times brighter than the Vela pulsar, which is normally the brightest source in the gamma-ray sky. The 3 hr peak flux was (85 +/- 5) x 10(-6) photons cm-2 s(-1), corresponding to an apparent isotropic luminosity of (2.1 +/- 0.2) x10(50) erg s(-1), the highest ever recorded for a blazar. In this Letter, we investigate the features of this exceptional event in the gamma-ray band of the Fermi-LAT. In contrast to previous flares of the same source observed with the Fermi-LAT, clear spectral changes are observed during the flare. C1 [Abdo, A. A.; Cheung, C. C.] Natl Acad Sci, Natl Res Council Res Associate, Washington, DC 20001 USA. [Ackermann, M.; Ajello, M.; Allafort, A.; Berenji, B.; Blandford, R. D.; Bloom, E. D.; Borgland, A. W.; Buehler, R.; Cameron, R. A.; Charles, E.; Chiang, J.; Claus, R.; Digel, S. W.; do Couto e Silva, E.; Drell, P. S.; Dubois, R.; Glanzman, T.; Godfrey, G.; Hayashida, M.; Johnson, A. S.; Kamae, T.; Lande, J.; Lee, S. -H.; Madejski, G. M.; Michelson, P. F.; Mitthumsiri, W.; Monzani, M. E.; Moskalenko, I. V.; Murgia, S.; Nolan, P. L.; Orlando, E.; Paneque, D.; Porter, T. A.; Reimer, A.; Reimer, O.; Tanaka, T.; Thayer, J. G.; Thayer, J. B.; Tramacere, A.; Vandenbroucke, J.; Vianello, G.; Waite, A. P.; Wang, P.] Stanford Univ, WW Hansen Expt Phys Lab, Kavli Inst Particle Astrophys & Cosmol, Dept Phys, Stanford, CA 94305 USA. [Ackermann, M.; Ajello, M.; Allafort, A.; Berenji, B.; Blandford, R. D.; Bloom, E. D.; Borgland, A. W.; Buehler, R.; Cameron, R. A.; Charles, E.; Chiang, J.; Claus, R.; Digel, S. W.; do Couto e Silva, E.; Drell, P. S.; Dubois, R.; Glanzman, T.; Godfrey, G.; Hayashida, M.; Johnson, A. S.; Kamae, T.; Lande, J.; Lee, S. -H.; Madejski, G. M.; Michelson, P. F.; Mitthumsiri, W.; Monzani, M. E.; Moskalenko, I. V.; Murgia, S.; Nolan, P. L.; Orlando, E.; Paneque, D.; Porter, T. A.; Reimer, A.; Reimer, O.; Tanaka, T.; Thayer, J. G.; Thayer, J. B.; Tramacere, A.; Vandenbroucke, J.; Vianello, G.; Waite, A. P.; Wang, P.] Stanford Univ, SLAC Natl Accelerator Lab, Stanford, CA 94305 USA. [Baldini, L.; Bellazzini, R.; Bregeon, J.; Kuss, M.; Latronico, L.; Pesce-Rollins, M.; Sgro, C.; Spandre, G.] Ist Nazl Fis Nucl, Sez Pisa, I-56127 Pisa, Italy. [Ballet, J.; Casandjian, J. M.; Grenier, I. A.; Naumann-Godo, M.; Pierbattista, M.; Tibaldo, L.] Univ Paris Diderot, Lab AIM, CEA IRFU, CNRS,CEA Saclay, F-91191 Gif Sur Yvette, France. [Barbiellini, G.; Longo, F.] Ist Nazl Fis Nucl, Sez Trieste, I-34127 Trieste, Italy. [Barbiellini, G.; Longo, F.] Univ Trieste, Dipartimento Fis, I-34127 Trieste, Italy. [Bastieri, D.; Buson, S.; Rando, R.; Tibaldo, L.] Ist Nazl Fis Nucl, Sez Padova, I-35131 Padua, Italy. [Bastieri, D.; Buson, S.; Rando, R.; Tibaldo, L.] Univ Padua, Dipartimento Fis G Galilei, I-35131 Padua, Italy. [Bonamente, E.; Cecchi, C.; Germani, S.; Lubrano, P.; Tosti, G.] Ist Nazl Fis Nucl, Sez Perugia, I-06123 Perugia, Italy. [Bonamente, E.; Cecchi, C.; Ciprini, S.; Germani, S.; Lubrano, P.; Tosti, G.] Univ Perugia, Dipartimento Fis, I-06123 Perugia, Italy. [Bouvier, A.; Ritz, S.; Sadrozinski, H. F. -W.; Schalk, T. L.; Ziegler, M.] Univ Calif Santa Cruz, Santa Cruz Inst Particle Phys, Dept Phys, Santa Cruz, CA 95064 USA. [Bouvier, A.; Ritz, S.; Sadrozinski, H. F. -W.; Schalk, T. L.; Ziegler, M.] Univ Calif Santa Cruz, Dept Astron & Astrophys, Santa Cruz, CA 95064 USA. [Brigida, M.; de Palma, F.; Favuzzi, C.; Fusco, P.; Giglietto, N.; Giordano, F.; Loparco, F.; Monte, C.; Raino, S.; Spinelli, P.] Univ Bari, Dipartimento Fis M Merlin, I-70126 Bari, Italy. [Brigida, M.; de Palma, F.; Favuzzi, C.; Fusco, P.; Giglietto, N.; Giordano, F.; Loparco, F.; Monte, C.; Raino, S.; Spinelli, P.] Politecn Bari, I-70126 Bari, Italy. [Brigida, M.; de Palma, F.; Favuzzi, C.; Fusco, P.; Gargano, F.; Giglietto, N.; Giordano, F.; Loparco, F.; Mazziotta, M. N.; Monte, C.; Raino, S.; Spinelli, P.] Ist Nazl Fis Nucl, Sez Bari, I-70126 Bari, Italy. [Bruel, P.; Fegan, S. J.; Fortin, P.; Horan, D.; Sanchez, D.] Ecole Polytech, CNRS, IN2P3, Lab Leprince Ringuet, F-91128 Palaiseau, France. [Caliandro, G. A.; Hadasch, D.; Torres, D. F.] Inst Ciencies Espai IEEC CSIC, Barcelona 08193, Spain. [Caraveo, P. A.] INAF Ist Astrofis Spaziale & Fis Cosm, I-20133 Milan, Italy. [Cavazzuti, E.; Cutini, S.; Gasparrini, D.; Giommi, P.] Agenzia Spaziale Italiana Sci Data Ctr, I-00044 Frascati, Roma, Italy. [Chekhtman, A.] Artep Inc, Excelsior Springs Court 2922, Ellicott City, MD 21042 USA. [Conrad, J.; Larsson, S.; Yang, Z.] Stockholm Univ, Dept Phys, SE-10691 Stockholm, Sweden. [D'Ammando, F.] IASF Palermo, I-90146 Palermo, Italy. [Conrad, J.; Larsson, S.; Yang, Z.] Oskar Klein Ctr Cosmoparticle Phys, SE-10691 Stockholm, Sweden. [D'Ammando, F.] INAF Ist Astrofis Spaziale & Fis Cosm, I-00133 Rome, Italy. [de Angelis, A.] Univ Udine, Dipartimento Fis, I-33100 Udine, Italy. [de Angelis, A.] Ist Nazl Fis Nucl, Sez Trieste, Grp Collegato Udine, I-33100 Udine, Italy. [Abdo, A. A.; Dermer, C. D.; Grove, J. E.; Lovellette, M. N.; Strickman, M. S.; Wood, K. S.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. [Dumora, D.; Escande, L.; Lott, B.] Univ Bordeaux 1, Ctr Etud Nucl Bordeaux Gradignan, CNRS, IN2P3, F-33175 Gradignan, France. [Escande, L.] CNRS, Ctr Etud Nucl Bordeaux Gradignan, IN2P3, UMR 5797, F-33175 Gradignan, France. [Ferrara, E. C.; Gehrels, N.; Hays, E.; McConville, W.; McEnery, J. E.; Moiseev, A. A.; Thompson, D. J.; Troja, E.] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA. [Fukazawa, Y.; Itoh, R.; Katagiri, H.; Mizuno, T.; Nishino, S.] Hiroshima Univ, Dept Phys Sci, Hiroshima 7398526, Japan. [Giroletti, M.] INAF Ist Radioastron, I-40129 Bologna, Italy. [Guiriec, S.] Univ Alabama, CSPAR, Huntsville, AL 35899 USA. [Johannesson, G.] Univ Iceland, Inst Sci, IS-107 Reykjavik, Iceland. [Kataoka, J.] Waseda Univ, Res Inst Sci & Engn, Shinjuku Ku, Tokyo 1698555, Japan. [Knoedlseder, J.; Vilchez, N.] CNRS, IRAP, F-31028 Toulouse 4, France. [Knoedlseder, J.; Vilchez, N.] Univ Toulouse, UPS OMP, IRAP, Toulouse, France. [Larsson, S.] Stockholm Univ, Dept Astron, SE-10691 Stockholm, Sweden. [Makeev, A.; Razzaque, S.] George Mason Univ, Coll Sci, Ctr Earth Observat & Space Res, Fairfax, VA 22030 USA. [McConville, W.; McEnery, J. E.; Moiseev, A. A.] Univ Maryland, Dept Phys, College Pk, MD 20742 USA. [McConville, W.; McEnery, J. E.; Moiseev, A. A.] Univ Maryland, Dept Astron, College Pk, MD 20742 USA. [Moiseev, A. A.] CRESST, Greenbelt, MD 20771 USA. [Morselli, A.; Vitale, V.] Ist Nazl Fis Nucl, Sez Roma Tor Vergata, I-00133 Rome, Italy. [Norris, J. P.; Ormes, J. F.] Univ Denver, Dept Phys & Astron, Denver, CO 80208 USA. [Nuss, E.; Pelassa, V.; Piron, F.; Vasileiou, V.] Univ Montpellier 2, Lab Phys Theor & Astroparticules, CNRS, IN2P3, Montpellier, France. [Ohsugi, T.; Takahashi, H.] Hiroshima Univ, Hiroshima Astrophys Sci Ctr, Hiroshima 7398526, Japan. [Okumura, A.; Takahashi, T.; Tanaka, Y.] JAXA, Inst Space & Astronaut Sci, Chuo Ku, Kanagawa 2525210, Japan. [Orlando, E.] Max Planck Inst Extraterr Phys, D-85748 Garching, Germany. [Paneque, D.] Max Planck Inst Phys & Astrophys, D-80805 Munich, Germany. [Reimer, A.; Reimer, O.] Leopold Franzens Univ Innsbruck, Inst Astro & Teilchenphys, A-6020 Innsbruck, Austria. [Reimer, A.; Reimer, O.] Leopold Franzens Univ Innsbruck, Inst Theoret Phys, A-6020 Innsbruck, Austria. [Roth, M.] Univ Washington, Dept Phys, Seattle, WA 98195 USA. [Scargle, J. D.] NASA, Ames Res Ctr, Div Space Sci, Moffett Field, CA 94035 USA. [Siskind, E. J.] NYCB Real Time Comp Inc, Lattingtown, NY 11560 USA. [Smith, P. D.; Winer, B. L.] Ohio State Univ, Dept Phys, Ctr Cosmol & Astroparticle Phys, Columbus, OH 43210 USA. [Torres, D. F.] ICREA, Barcelona, Spain. [Tramacere, A.; Vianello, G.] CIFS, I-10133 Turin, Italy. [Tramacere, A.] INTEGRAL Sci Data Ctr, CH-1290 Versoix, Switzerland. [Vitale, V.] Univ Roma Tor Vergata, Dipartimento Fis, I-00133 Rome, Italy. RP Abdo, AA (reprint author), USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. EM charles.dermer@nrl.navy.mil; escande@cenbg.in2p3.fr; lott@cenbg.in2p3.fr RI Johannesson, Gudlaugur/O-8741-2015; Moskalenko, Igor/A-1301-2007; Mazziotta, Mario /O-8867-2015; Sgro, Carmelo/K-3395-2016; Torres, Diego/O-9422-2016; Orlando, E/R-5594-2016; Morselli, Aldo/G-6769-2011; Hays, Elizabeth/D-3257-2012; Loparco, Francesco/O-8847-2015; Thompson, David/D-2939-2012; Gehrels, Neil/D-2971-2012; McEnery, Julie/D-6612-2012; Baldini, Luca/E-5396-2012; lubrano, pasquale/F-7269-2012; Kuss, Michael/H-8959-2012; giglietto, nicola/I-8951-2012; Reimer, Olaf/A-3117-2013; Tosti, Gino/E-9976-2013; Rando, Riccardo/M-7179-2013; Gargano, Fabio/O-8934-2015 OI Cutini, Sara/0000-0002-1271-2924; Gasparrini, Dario/0000-0002-5064-9495; Tramacere, Andrea/0000-0002-8186-3793; Baldini, Luca/0000-0002-9785-7726; Johannesson, Gudlaugur/0000-0003-1458-7036; Moskalenko, Igor/0000-0001-6141-458X; Mazziotta, Mario /0000-0001-9325-4672; Torres, Diego/0000-0002-1522-9065; giommi, paolo/0000-0002-2265-5003; De Angelis, Alessandro/0000-0002-3288-2517; Caraveo, Patrizia/0000-0003-2478-8018; Sgro', Carmelo/0000-0001-5676-6214; Rando, Riccardo/0000-0001-6992-818X; Bastieri, Denis/0000-0002-6954-8862; Pesce-Rollins, Melissa/0000-0003-1790-8018; Giroletti, Marcello/0000-0002-8657-8852; Morselli, Aldo/0000-0002-7704-9553; Loparco, Francesco/0000-0002-1173-5673; Thompson, David/0000-0001-5217-9135; lubrano, pasquale/0000-0003-0221-4806; giglietto, nicola/0000-0002-9021-2888; Reimer, Olaf/0000-0001-6953-1385; Gargano, Fabio/0000-0002-5055-6395 FU K. A. Wallenberg Foundation; International Doctorate on Astroparticle Physics (IDAPP) program FX Royal Swedish Academy of Sciences Research Fellow, funded by a grant from the K. A. Wallenberg Foundation.; Partially supported by the International Doctorate on Astroparticle Physics (IDAPP) program. NR 23 TC 80 Z9 80 U1 0 U2 9 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 2041-8205 J9 ASTROPHYS J LETT JI Astrophys. J. Lett. PD JUN 1 PY 2011 VL 733 IS 2 AR L26 DI 10.1088/2041-8205/733/2/L26 PG 7 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 797NQ UT WOS:000293135000010 ER PT J AU Dermer, CD Cavadini, M Razzaque, S Finke, JD Chiang, J Lott, B AF Dermer, Charles D. Cavadini, Massimo Razzaque, Soebur Finke, Justin D. Chiang, James Lott, Benoit TI TIME DELAY OF CASCADE RADIATION FOR TeV BLAZARS AND THE MEASUREMENT OF THE INTERGALACTIC MAGNETIC FIELD SO ASTROPHYSICAL JOURNAL LETTERS LA English DT Article DE galaxies: jets; gamma rays: galaxies; radiation mechanisms: non-thermal ID ACTIVE GALACTIC NUCLEI; EXTRAGALACTIC BACKGROUND LIGHT; LARGE-AREA TELESCOPE; GAMMA-RAY BURSTS; FERMI OBSERVATIONS; EMISSION; CONSTRAINTS; HALOS; ERA AB Recent claims that the strength B-IGMF of the intergalactic magnetic field (IGMF) is greater than or similar to 10(-15) G are based on upper limits to the expected cascade flux in the GeV band produced by blazar TeV photons absorbed by the extragalactic background light. This limit depends on an assumption that the mean blazar TeV flux remains constant on timescales greater than or similar to 2(B-IGMF/10(-18)G)(2)/(E/10 GeV)(2) yr for an IGMF coherence length approximate to 1 Mpc, where E is the measured photon energy. Restricting TeV activity of 1ES 0229+200 to approximate to 3-4 years during which the source has been observed leads to a more robust lower limit of B-IGMF greater than or similar to 10(-18) G, which can be larger by an order of magnitude if the intrinsic source flux above approximate to 5-10 TeV from 1ES 0229+200 is strong. C1 [Dermer, Charles D.; Razzaque, Soebur; Finke, Justin D.] USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. [Cavadini, Massimo] Univ Insubria, Dipartimento Matemat & Fis, I-22100 Como, Italy. [Chiang, James] Stanford Univ, WW Hansen Expt Phys Lab, Kavli Inst Particle Astrophys & Cosmol, Dept Phys, Stanford, CA 94305 USA. [Chiang, James] Stanford Univ, SLAC Natl Accelerator Lab, Stanford, CA 94305 USA. [Lott, Benoit] CNRS IN2P3, Ctr Etud Nucl Bordeaux Gradignan, UMR 5797, F-33175 Gradignan, France. [Lott, Benoit] 40 Univ Bordeaux, Ctr Etud Nucl Bordeaux Gradignan, UMR 5797, F-33175 Gradignan, France. RP Dermer, CD (reprint author), USN, Res Lab, Div Space Sci, Washington, DC 20375 USA. EM charles.dermer@nrl.navy.mil FU NASA [DPR 76-644-10]; NRL High Energy Space Environment Branch; Office of Naval Research FX We thank J. Perkins for discussions about the VERITAS data, the VERITAS team for kindly allowing us to show their preliminary 1ES 0229+200 data, and the referee for a constructive report. This work is supported by NASA Fermi Guest Investigator Program DPR 76-644-10. M. C. acknowledges the support and hospitality of the NRL High Energy Space Environment Branch during his visit. The work of C. D. D. and J. D. F. is also supported by the Office of Naval Research. NR 31 TC 98 Z9 98 U1 0 U2 5 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 2041-8205 J9 ASTROPHYS J LETT JI Astrophys. J. Lett. PD JUN 1 PY 2011 VL 733 IS 2 AR L21 DI 10.1088/2041-8205/733/2/L21 PG 5 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 797NQ UT WOS:000293135000005 ER PT J AU Vourlidas, A Colaninno, R Nieves-Chinchilla, T Stenborg, G AF Vourlidas, A. Colaninno, R. Nieves-Chinchilla, T. Stenborg, G. TI THE FIRST OBSERVATION OF A RAPIDLY ROTATING CORONAL MASS EJECTION IN THE MIDDLE CORONA SO ASTROPHYSICAL JOURNAL LETTERS LA English DT Article DE Sun: activity; Sun: coronal mass ejections (CMEs) ID CONE MODEL; FLUX ROPE; HALO CMES; HELIOSPHERE; CONNECTION; SPACE; FIELD; LINE AB In this Letter, we present the first direct detection of a rotating coronal mass ejection (CME) in the middle corona (5-15 R-circle dot). The CME rotation rate is 60 degrees day(-1), which is the highest rate reported yet. The Earth-directed event was observed by the STEREO/SECCHI and SOHO/LASCO instruments. We are able to derive the three-dimensional morphology and orientation of the CME flux rope by applying a forward-fitting model to simultaneous observations from three vantage points (SECCHI-A, -B, LASCO). Surprisingly, we find that even such rapidly rotating CME does not result in significant projection effects (variable angular width) in any single coronagraph view. This finding may explain the prevalent view of constant angular width for CMEs above 5 R-circle dot and the lack of detections of rotating CMEs in the past. Finally, the CME is a "stealth" CME with very weak low corona signatures as viewed from Earth. It originated from a quiet-Sun neutral line. We tentatively attribute the fast rotation to a possible disconnection of one of the CME footpoints early in the eruption. We discuss the implications of such rotations to space weather prediction. C1 [Vourlidas, A.; Colaninno, R.] USN, Res Lab, Solar Phys Branch, Div Space Sci, Washington, DC 20375 USA. [Nieves-Chinchilla, T.] Catholic Univ Amer, Dept Phys, Washington, DC 20064 USA. [Stenborg, G.] Interferometrics Inc, Herdon, VA USA. RP Vourlidas, A (reprint author), USN, Res Lab, Solar Phys Branch, Div Space Sci, Washington, DC 20375 USA. RI Nieves-Chinchilla, Teresa/F-3482-2016; Vourlidas, Angelos/C-8231-2009 OI Nieves-Chinchilla, Teresa/0000-0003-0565-4890; Vourlidas, Angelos/0000-0002-8164-5948 FU NASA [NNH08AI50I] FX We thank O. C. St. Cyr for useful discussions. The AIA data used here are courtesy of SDO (NASA) and the AIA consortium. The SECCHI data are courtesy of STEREO (NASA) and the SECCHI consortium. A.V.'s work is supported by NASA grant NNH08AI50I. NR 25 TC 34 Z9 36 U1 0 U2 9 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 2041-8205 J9 ASTROPHYS J LETT JI Astrophys. J. Lett. PD JUN 1 PY 2011 VL 733 IS 2 AR L23 DI 10.1088/2041-8205/733/2/L23 PG 6 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 797NQ UT WOS:000293135000007 ER PT J AU Reeder, DB AF Reeder, Davis Benjamin TI FISH ACOUSTICS: PHYSICS-BASED MODELING AND MEASUREMENT SO JOURNAL OF MARINE SCIENCE AND TECHNOLOGY-TAIWAN LA English DT Article DE underwater acoustics; fish acoustics; backscatter; target strength; attenuation; measurement; modeling ID FILLED CYLINDERS; SCATTERING; SWIMBLADDERS; SYSTEMS; TARGET; SOUND AB The U.S. Office of Naval Research has sponsored research in the area of marine organism acoustics for many years. The research program has included development of theoretical physics-based acoustic scattering models of single animals, high-resolution laboratory measurements of scattering by individual animals, and at-sea field experiments. The program has been focused on the backscattered signal, but has also included investigation of the forward-scattered signal. Downward-looking acoustic surveys using ship borne echosounders rely on the backscattered signal and provide non-invasive, non-destructive, rapid, high-resolution, large area survey capability compared to traditional net tows. Horizontally-oriented acoustic surveys provide the opportunity to investigate both the backscattered and forward-scattered signals from marine organisms and their impact on long-range acoustic propagation characteristics in the shallow water environment. Both cases require an understanding of the scattering characteristics of each type of organism and aggregation in the acoustic path as a function of acoustic frequency and orientation relative to the acoustic source and receiver. This overview of the fish-related acoustics research program includes representative examples which demonstrate the fundamental physical principles which have shaped the program. C1 Off Naval Res, Arlington, VA 22217 USA. RP Reeder, DB (reprint author), Off Naval Res, Code 32, Arlington, VA 22217 USA. EM reederd@onr.navy.mil NR 18 TC 1 Z9 1 U1 1 U2 6 PU NATL TAIWAN OCEAN UNIV PI KEELUNG PA NO 2 PEI-NING RD, KEELUNG, 202, TAIWAN SN 1023-2796 J9 J MAR SCI TECH-TAIW JI J. Mar. Sci. Technol.-Taiwan PD JUN PY 2011 VL 19 IS 3 BP 273 EP 278 PG 6 WC Engineering, Multidisciplinary; Oceanography SC Engineering; Oceanography GA 798IF UT WOS:000293195700006 ER PT J AU Mahnken, TG AF Mahnken, Thomas G. TI Weapons: The Growth & Spread of the Precision-Strike Regime SO DAEDALUS LA English DT Article AB For two decades, scholars and practitioners have argued that the world is experiencing a Revolution in Military Affairs brought on by the development and diffusion of precision-strike and related capabilities. The United States took an early lead in exploiting the promise of precision-strike systems, and the use of precision weaponry has given the United States a battlefield edge for twenty years. However, these weapons are now spreading: other countries, and non-state actors, are acquiring them and developing countermeasures against them. As the precision-strike regime matures, the United States will see its edge erode. The ability of the United States to project power will diminish considerably. In addition, U.S. forces, and eventually the United States itself, will be increasingly vulnerable to precision weapons in the hands of our adversaries. C1 [Mahnken, Thomas G.] USN, War Coll, Washington, DC USA. RP Mahnken, TG (reprint author), Johns Hopkins Univ, Philip Merrill Ctr Strateg Studies, Baltimore, MD 21218 USA. NR 44 TC 6 Z9 6 U1 1 U2 8 PU MIT PRESS PI CAMBRIDGE PA 55 HAYWARD STREET, CAMBRIDGE, MA 02142 USA SN 0011-5266 J9 DAEDALUS-US JI Daedalus PD SUM PY 2011 VL 140 IS 3 BP 45 EP 57 PG 13 WC Humanities, Multidisciplinary; Social Sciences, Interdisciplinary SC Arts & Humanities - Other Topics; Social Sciences - Other Topics GA 793UP UT WOS:000292849700005 ER PT J AU Carmona-Martinez, AA Harnisch, F Fitzgerald, LA Biffinger, JC Ringeisen, BR Schroder, U AF Carmona-Martinez, Alessandro A. Harnisch, Falk Fitzgerald, Lisa A. Biffinger, Justin C. Ringeisen, Bradley R. Schroeder, Uwe TI Cyclic voltammetric analysis of the electron transfer of Shewanella oneidensis MR-1 and nanofilament and cytochrome knock-out mutants SO BIOELECTROCHEMISTRY LA English DT Article DE Microbial bioelectrochemical systems; Microbial fuel cells; Bacterial electron transfer; Shewanella oneidensis; Cyclic voltammetry ID MICROBIAL FUEL-CELLS; REDUCING BACTERIUM; POWER; ELECTROCHEMISTRY; MECHANISMS; NANOWIRES; ACCEPTORS; TRANSPORT; FLAVINS; BINDING AB Shewanella is frequently used as a model microorganism for microbial bioelectrochemical systems. In this study, we used cyclic voltammetry (CV) to investigate extracellular electron transfer mechanisms from S. oneidensis MR-1 (WT) and five deletion mutants: membrane bound cytochrome (Delta mtrC/Delta omcA), transmembrane pili (Delta pilM-Q, Delta mshH-Q, and Delta pilM-Q/Delta mshH-Q) and flagella (Delta flg). We demonstrate that the formal potentials of mediated and direct electron transfer sites of the derived biofilms can be gained from CVs of the respective biofilms recorded at bioelectrocatlytic (i.e. turnover) and lactate depleted (i.e. non-turnover) conditions. As the biofilms possess only a limited bioelectrocatalytic activity, an advanced data processing procedure, using the open-source software SOAS, was applied. The obtained results indicate that S. oneidensis mutants used in this study are able to bypass hindered direct electron transfer by alternative redox proteins as well as self-mediated pathways. (C) 2011 Elsevier B.V. All rights reserved. C1 [Carmona-Martinez, Alessandro A.; Harnisch, Falk; Schroeder, Uwe] Tech Univ Carolo Wilhelmina Braunschweig, Inst Environm & Sustainable Chem, D-38106 Braunschweig, Germany. [Fitzgerald, Lisa A.; Biffinger, Justin C.; Ringeisen, Bradley R.] USN, Res Lab, Div Chem, Washington, DC 20375 USA. RP Harnisch, F (reprint author), Tech Univ Carolo Wilhelmina Braunschweig, Inst Environm & Sustainable Chem, Hagenring 30, D-38106 Braunschweig, Germany. EM f.harnisch@tu-braunschweig.de RI Carmona-Martinez, Alessandro/J-1352-2014; OI Harnisch, Falk/0000-0002-0014-4640 FU DAAD; Fonds der Chemischen Industrie (FCI); Office of Naval Research (ONR) through NRL [61153N]; Air Force Office for Scientific Research (AFOSR) through MIPR [F1ATA00060G002] FX The authors thank Luciano D. Dantas for help with the Linux and SOAS software handling and Daad Saffarini (U of Wisconsin-Milwaukee, WI) and group for the mutant strains of S. oneidensis. A. A. C.-M. thanks the DAAD for a Ph.D. scholarship. F.H. acknowledges the support by the Fonds der Chemischen Industrie (FCI). U.S. acknowledges the foundation of the professorship Sustainable Chemistry and Energy Research by the Volkswagen AG and the Verband der Deutschen Biokraftstoffindustrie e.V. L.A.F., J.C.B. and B.R.R. thank the Office of Naval Research (ONR) for funding through NRL base core support PE#61153N, and the Air Force Office for Scientific Research (AFOSR) for funding through MIPR#F1ATA00060G002. NR 47 TC 66 Z9 67 U1 6 U2 95 PU ELSEVIER SCIENCE SA PI LAUSANNE PA PO BOX 564, 1001 LAUSANNE, SWITZERLAND SN 1567-5394 J9 BIOELECTROCHEMISTRY JI Bioelectrochemistry PD JUN PY 2011 VL 81 IS 2 BP 74 EP 80 DI 10.1016/j.bioelechem.2011.02.006 PG 7 WC Biochemistry & Molecular Biology; Biology; Biophysics; Electrochemistry SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Biophysics; Electrochemistry GA 790KX UT WOS:000292588000003 PM 21402501 ER PT J AU Hutchins, TE AF Hutchins, Todd Emerson TI Structuring a Sustainable Letters of Marque Regime: How Commissioning Privateers Can Defeat the Somali Pirates SO CALIFORNIA LAW REVIEW LA English DT Article ID WAR POWERS; REPRISAL; LAW; SEA AB Piracy is a complex problem that threatens maritime safety and interferes with global commerce. Supported by networks of financiers and negotiators, Somali pirates viciously attack seafarers across expansive stretches of the Indian Ocean. Despite costly naval interventions, pirates continue to strike. Powerful nations from around the globe have been unsuccessful at stemming the problem because they have focused on capturing and prosecuting a relatively small number of seagoing pirates, while allowing pirate networks to operate with near impunity. To prevent future attacks., an effective and sustainable deterrence regime must be implemented to target the financiers and sophisticated kingpins who lead pirate networks. This Comment examines a new approach based on an age-old solution privateers. The U.S. Constitution expressly provides that Congress, by issuing letters of marque, can enable private entities to conduct maritime warfare on behalf of the nation. Successive generations of American governments have employed letters of marque to combat maritime threats efficiently. Once more, the commissioning of privateers might prove to be an appropriate tool in the battle to dismantle pirate networks. Given the dispersed nature of the problem and relatively limited capabilities of the pirates, this Comment argues that privateers may provide a more cost-effective and sustainable approach than deploying naval forces. It suggests how a new regime for deploying privateers against Somali pirates could and should be established consistent with international law under either international or domestic frameworks. RP Hutchins, TE (reprint author), USN, Justice Sch, Newport, RI 02841 USA. NR 280 TC 4 Z9 4 U1 1 U2 3 PU UNIV CALIFORNIA BERKELEY SCH LAW PI BERKELEY PA BOAT HALL, 588 SIMON HALL, BERKELEY, CA 94720-7200 USA SN 0008-1221 J9 CALIF LAW REV JI Calif. Law Rev. PD JUN PY 2011 VL 99 IS 3 BP 819 EP 884 PG 66 WC Law SC Government & Law GA 790WR UT WOS:000292622000002 ER PT J AU Lutgendorf, MA Schindler, LL Hill, JB Magann, EF O'Boyle, JD AF Lutgendorf, Monica A. Schindler, Lynnett L. Hill, James B. Magann, Everett F. O'Boyle, John D. TI Implementation of a Protocol to Reduce Occurrence of Retained Sponges After Vaginal Delivery SO MILITARY MEDICINE LA English DT Article ID SURGERY AB Background: Retained sponges (gossypiboma) following vaginal delivery are an uncommon occurrence. Although significant morbidity from such an event is unlikely, there are many reported adverse effects, including symptoms of malodorous discharge, loss of confidence in providers and the medical system, and legal claims. Objective: To report a protocol intended to reduce the occurrence of retained sponges following vaginal delivery. Methods: After identification of limitations with existing delivery room protocols, we developed a sponge count protocol to reduce occurrence of retained vaginal sponges. We report our experience at Naval Medical Center Portsmouth, a large tertiary care military treatment facility with our efforts to implement a sponge count protocol to reduce retained sponges following vaginal delivery. Conclusions: With appropriate pre-implementation training, protocols which incorporate post-delivery vaginal sweep and sponge counts are well accepted by the health care team and can be incorporated into the delivery room routine. C1 [Lutgendorf, Monica A.; Schindler, Lynnett L.; Hill, James B.; Magann, Everett F.; O'Boyle, John D.] USN, Med Ctr Portsmouth, Dept Obstet & Gynecol, Portsmouth, VA 23708 USA. RP Lutgendorf, MA (reprint author), USN, Med Ctr Portsmouth, Dept Obstet & Gynecol, 620 John Paul Jones Circle, Portsmouth, VA 23708 USA. NR 5 TC 5 Z9 6 U1 0 U2 1 PU ASSOC MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA SN 0026-4075 J9 MIL MED JI Milit. Med. PD JUN PY 2011 VL 176 IS 6 BP 702 EP 704 PG 3 WC Medicine, General & Internal SC General & Internal Medicine GA 792XN UT WOS:000292783800024 PM 21702393 ER PT J AU Johnson, LA Johnson, RL Alfonzo, C AF Johnson, Lucas A. Johnson, Rebecca L. Alfonzo, Chris TI Spice: A Legal Marijuana Equivalent SO MILITARY MEDICINE LA English DT Article AB Spice, an herbal mixture containing synthetic cannabinoids, is a legal drug increasingly abused by adolescents and young adults for its narcotic-like effects. A paucity of English language literature exists on the clinical effects of Spice use. A case report of substance-induced psychosis and a summary of available literature follows later. C1 [Johnson, Lucas A.] III Marine Expeditionary Force, Marine Headquarters Grp 3, Unit 35640, FPO, AP 96606 USA. [Johnson, Rebecca L.] III Marine Expeditionary Force, Marine Logist Grp 3, Unit 38463, FPO, AP 96604 USA. [Alfonzo, Chris] USN, Dept Psychiat, Aerosp Med Inst, Pensacola, FL 32508 USA. RP Johnson, LA (reprint author), III Marine Expeditionary Force, Marine Headquarters Grp 3, Unit 35640, FPO, AP 96606 USA. NR 21 TC 27 Z9 28 U1 0 U2 3 PU ASSOC MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA SN 0026-4075 J9 MIL MED JI Milit. Med. PD JUN PY 2011 VL 176 IS 6 BP 718 EP 720 PG 3 WC Medicine, General & Internal SC General & Internal Medicine GA 792XN UT WOS:000292783800028 PM 21702397 ER PT J AU Carroll, TL AF Carroll, T. L. TI Detecting variation in chaotic attractors SO CHAOS LA English DT Article ID STRANGE ATTRACTORS; SYSTEMS AB If the output of an experiment is a chaotic signal, it may be useful to detect small changes in the signal, but there are a limited number of ways to compare signals from chaotic systems, and most known methods are not robust in the presence of noise. One may calculate dimension or Lyapunov exponents from the signal, or construct a synchronizing model, but all of these are only useful in low noise situations. I introduce a method for detecting small variations in a chaotic attractor based on directly calculating the difference between vector fields in phase space. The differences are found by comparing close strands in phase space, rather than close neighbors. The use of strands makes the method more robust to noise and more sensitive to small attractor differences. [doi:10.1063/1.3602221] C1 USN, Res Lab, Washington, DC 20375 USA. RP Carroll, TL (reprint author), USN, Res Lab, Washington, DC 20375 USA. EM Thomas.Carroll@nrl.navy.mil OI Carroll, Thomas/0000-0002-2371-2049 NR 15 TC 6 Z9 6 U1 0 U2 3 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 1054-1500 J9 CHAOS JI Chaos PD JUN PY 2011 VL 21 IS 2 AR 023128 DI 10.1063/1.3602221 PG 6 WC Mathematics, Applied; Physics, Mathematical SC Mathematics; Physics GA 786TH UT WOS:000292330300028 PM 21721770 ER PT J AU Olson, CC Nichols, JM Michalowicz, JV Bucholtz, F AF Olson, C. C. Nichols, J. M. Michalowicz, J. V. Bucholtz, F. TI Signal design using nonlinear oscillators and evolutionary algorithms: Application to phase-locked loop disruption SO CHAOS LA English DT Article ID UNIVERSAL CIRCUIT; GENERATING CHAOS; OPTIMIZATION; EXCITATIONS; REACTORS; SYSTEMS AB This work describes an approach for efficiently shaping the response characteristics of a fixed dynamical system by forcing with a designed input. We obtain improved inputs by using an evolutionary algorithm to search a space of possible waveforms generated by a set of nonlinear, ordinary differential equations (ODEs). Good solutions are those that result in a desired system response subject to some input efficiency constraint, such as signal power. In particular, we seek to find inputs that best disrupt a phase-locked loop (PLL). Three sets of nonlinear ODEs are investigated and found to have different disruption capabilities against a model PLL. These differences are explored and implications for their use as input signal models are discussed. The PLL was chosen here as an archetypal example but the approach has broad applicability to any input/output system for which a desired input cannot be obtained analytically. (C) 2011 American Institute of Physics. [doi:10.1063/1.3597650] C1 [Olson, C. C.; Michalowicz, J. V.] Sotera Def Solut Inc, Crofton, MD USA. [Olson, C. C.; Nichols, J. M.; Michalowicz, J. V.; Bucholtz, F.] USN, Res Lab, Div Opt Sci, Washington, DC 20375 USA. RP Olson, CC (reprint author), Sotera Def Solut Inc, Crofton, MD USA. EM colin.olson.ctr@nrl.navy.mil NR 34 TC 1 Z9 1 U1 1 U2 4 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 1054-1500 J9 CHAOS JI Chaos PD JUN PY 2011 VL 21 IS 2 AR 023136 DI 10.1063/1.3597650 PG 12 WC Mathematics, Applied; Physics, Mathematical SC Mathematics; Physics GA 786TH UT WOS:000292330300036 PM 21721778 ER PT J AU Hall, A Petersen, K Koller, W Patel, P Mendoza, M Li, A deChickera, S Foster, P Dekaban, G AF Hall, Aaron Petersen, Kyle Koller, Wayne Patel, Pratik Mendoza, Mirian Li, Alex deChickera, Sonali Foster, Paula Dekaban, Gregory TI DEVELOPMENT OF A RODENT MODEL OF DECOMPRESSION SICKNESS INDUCED SPINAL CORD INJURY SO JOURNAL OF NEUROTRAUMA LA English DT Meeting Abstract CT 29th Annual National Neurotrauma Symposium CY JUL 10-13, 2011 CL Hollywood Beach, FL C1 [Hall, Aaron; Petersen, Kyle; Koller, Wayne; Patel, Pratik; Mendoza, Mirian] USN, Med Res Ctr, Dept Undersea Med, Silver Spring, MD USA. [Li, Alex] Robarts Res Inst, Ctr Mind & Metab Imaging, London, ON N6A 5C1, Canada. [Foster, Paula] Robarts Res Inst, Imaging Res Grp, London, ON N6A 5C1, Canada. [deChickera, Sonali; Dekaban, Gregory] Robarts Res Inst, BioTherapeut Res Lab, London, ON N6A 5C1, Canada. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MARY ANN LIEBERT INC PI NEW ROCHELLE PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA SN 0897-7151 J9 J NEUROTRAUM JI J. Neurotrauma PD JUN PY 2011 VL 28 IS 6 BP A25 EP A25 PG 1 WC Critical Care Medicine; Clinical Neurology; Neurosciences SC General & Internal Medicine; Neurosciences & Neurology GA 788PT UT WOS:000292457600090 ER PT J AU Mietus, C Browne, K Meng, X Wolf, J Smith, D Adeeb, S Kawoos, U Rosen, A Chavko, M Cullen, DK AF Mietus, Constance Browne, Kevin Meng, Xu Wolf, John Smith, Douglas Adeeb, Saleena Kawoos, Usmah Rosen, Arye Chavko, Mikulas Cullen, D. Kacy TI NEUROANATOMICAL PATTERNS OF BIOPHYSICAL RESPONSES AND NEUROPATHOLOGY BASED ON ORIENTATION TO BLAST WAVE SO JOURNAL OF NEUROTRAUMA LA English DT Meeting Abstract CT 29th Annual National Neurotrauma Symposium CY JUL 10-13, 2011 CL Hollywood Beach, FL C1 [Mietus, Constance; Browne, Kevin; Wolf, John; Smith, Douglas; Cullen, D. Kacy] Univ Penn, Dept Neurosurg, Ctr Brain Injury & Repair, Philadelphia, PA 19104 USA. [Meng, Xu; Rosen, Arye] Drexel Univ, Sch Biomed Engn Sci & Hlth Syst, Philadelphia, PA 19104 USA. [Adeeb, Saleena; Kawoos, Usmah] USN, Dept Trauma & Resuscitat Med, Res Ctr, Silver Spring, MD USA. NR 0 TC 0 Z9 0 U1 0 U2 1 PU MARY ANN LIEBERT INC PI NEW ROCHELLE PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA SN 0897-7151 J9 J NEUROTRAUM JI J. Neurotrauma PD JUN PY 2011 VL 28 IS 6 BP A99 EP A100 PG 2 WC Critical Care Medicine; Clinical Neurology; Neurosciences SC General & Internal Medicine; Neurosciences & Neurology GA 788PT UT WOS:000292457600312 ER PT J AU Moratz, C Burton, E Morgan, A Schrot, J McCarron, R Liu, YB Myers, M McCabe, J AF Moratz, Chantal Burton, Ellen Morgan, Amy Schrot, John McCarron, Richard Liu, Yunbo Myers, Matthew McCabe, Joseph TI RAT BLOOD-BRAIN BARRIER DISRUPTION AND NEUROIMMUNE ALTERATIONS FROM NON-IMPACT PRESSURE ALTERATIONS BY HIGH-INTENSITY FOCUSED ULTRASOUND AND BLAST OVERPRESSURE SHOCK TUBE EXPOSURE SO JOURNAL OF NEUROTRAUMA LA English DT Meeting Abstract CT 29th Annual National Neurotrauma Symposium CY JUL 10-13, 2011 CL Hollywood Beach, FL C1 [Moratz, Chantal] Uniformed Serv Univ Hlth Sci, Dept Med, Bethesda, MD 20814 USA. [Burton, Ellen; Morgan, Amy] USUHS, Ctr Neurosci & Regenerat Med, Bethesda, MD USA. [Schrot, John; McCarron, Richard] USN, Med Res Ctr, Silver Spring, MD USA. [Liu, Yunbo; Myers, Matthew] US FDA, Ctr Devices & Radiol Hlth, White Oak, MD USA. [McCabe, Joseph] USUHS, Dept Anat Physiol & Genet, Bethesda, MD USA. NR 0 TC 0 Z9 0 U1 0 U2 1 PU MARY ANN LIEBERT INC PI NEW ROCHELLE PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA SN 0897-7151 J9 J NEUROTRAUM JI J. Neurotrauma PD JUN PY 2011 VL 28 IS 6 BP A76 EP A76 PG 1 WC Critical Care Medicine; Clinical Neurology; Neurosciences SC General & Internal Medicine; Neurosciences & Neurology GA 788PT UT WOS:000292457600241 ER PT J AU Shah, A Stemper, B Yoganandan, N Shender, B AF Shah, Alok Stemper, Brian Yoganandan, Narayan Shender, Barry TI PRESSURE PROFILES AND ATTENUATION CHARACTERISTICS OF SHOCKWAVES USING POST MORTEM HUMAN SUBJECT MODEL FOR BLAST-INDUCED MILD TRAUMATIC BRAIN INJURY SO JOURNAL OF NEUROTRAUMA LA English DT Meeting Abstract CT 29th Annual National Neurotrauma Symposium CY JUL 10-13, 2011 CL Hollywood Beach, FL C1 [Shah, Alok; Stemper, Brian; Yoganandan, Narayan; Shender, Barry] Med Coll Wisconsin, Milwaukee, WI 53226 USA. [Shender, Barry] USN, Air Warfare Ctr, Div Aircraft, Patuxent River, MD USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MARY ANN LIEBERT INC PI NEW ROCHELLE PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA SN 0897-7151 J9 J NEUROTRAUM JI J. Neurotrauma PD JUN PY 2011 VL 28 IS 6 BP A59 EP A59 PG 1 WC Critical Care Medicine; Clinical Neurology; Neurosciences SC General & Internal Medicine; Neurosciences & Neurology GA 788PT UT WOS:000292457600191 ER PT J AU Shaughness, M Maudlin-Jeronimo, E Hall, A Shear, D McCarron, R Stone, J Ahlers, S AF Shaughness, Michael Maudlin-Jeronimo, Eric Hall, Aaron Shear, Deborah McCarron, Richard Stone, James Ahlers, Stephen TI EVALUATION OF CORTICOSTERONE AFTER REPEATED EXPOSURE TO LOW LEVEL BLAST OVERPRESSURE IN RATS SO JOURNAL OF NEUROTRAUMA LA English DT Meeting Abstract CT 29th Annual National Neurotrauma Symposium CY JUL 10-13, 2011 CL Hollywood Beach, FL C1 [Shaughness, Michael; Maudlin-Jeronimo, Eric; Hall, Aaron; McCarron, Richard; Ahlers, Stephen] USN, Med Res Ctr, Silver Spring, MD USA. [Shear, Deborah] Walter Reed Army Inst Res, Silver Spring, MD USA. [Stone, James] Univ Virginia, Sch Med, Charlottesville, VA 22908 USA. NR 0 TC 0 Z9 0 U1 0 U2 1 PU MARY ANN LIEBERT INC PI NEW ROCHELLE PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA SN 0897-7151 J9 J NEUROTRAUM JI J. Neurotrauma PD JUN PY 2011 VL 28 IS 6 BP A61 EP A62 PG 2 WC Critical Care Medicine; Clinical Neurology; Neurosciences SC General & Internal Medicine; Neurosciences & Neurology GA 788PT UT WOS:000292457600199 ER PT J AU Tustison, N Avants, B Cook, P Kim, J Whyte, J Gee, J Ahlers, S Stone, J AF Tustison, Nicholas Avants, Brian Cook, Philip Kim, Junghoon Whyte, John Gee, James Ahlers, Stephen Stone, James TI MULTIVARIATE ANALYSIS OF DIFFUSION TENSOR IMAGING AND CORTICAL THICKNESS MAPS IN A TRAUMATIC BRAIN INJURY (TBI) COHORT USING ADVANCED NORMALIZATION TOOLS (ANTS) SO JOURNAL OF NEUROTRAUMA LA English DT Meeting Abstract CT 29th Annual National Neurotrauma Symposium CY JUL 10-13, 2011 CL Hollywood Beach, FL C1 [Tustison, Nicholas; Stone, James] Univ Virginia, Charlottesville, VA USA. [Avants, Brian; Cook, Philip; Gee, James] Univ Penn, Philadelphia, PA 19104 USA. [Kim, Junghoon; Whyte, John] Moss Rehabil Res Inst, Philadelphia, PA USA. [Ahlers, Stephen] USN, Med Res Ctr, Silver Spring, MD USA. NR 0 TC 1 Z9 1 U1 0 U2 0 PU MARY ANN LIEBERT INC PI NEW ROCHELLE PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA SN 0897-7151 J9 J NEUROTRAUM JI J. Neurotrauma PD JUN PY 2011 VL 28 IS 6 BP A111 EP A111 PG 1 WC Critical Care Medicine; Clinical Neurology; Neurosciences SC General & Internal Medicine; Neurosciences & Neurology GA 788PT UT WOS:000292457600346 ER PT J AU Wang, YS Chavko, M Weiss, T Adeeb, S McCarron, R Yu, S AF Wang, Yushan Chavko, Mikulas Weiss, Tracy Adeeb, Saleena McCarron, Richard Yu, Simon TI CHANGES IN GLUTAMATE RECEPTOR TRAFFICKING IN BLAST-INDUCED TRAUMATIC BRAIN INJURY IN THE RAT SO JOURNAL OF NEUROTRAUMA LA English DT Meeting Abstract CT 29th Annual National Neurotrauma Symposium CY JUL 10-13, 2011 CL Hollywood Beach, FL C1 [Wang, Yushan; Weiss, Tracy; Yu, Simon] Def R&D Canada Suffield, Medicine Hat, AB, Canada. [Chavko, Mikulas; Adeeb, Saleena; McCarron, Richard] USN, Med Res Ctr, Silver Spring, MD USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MARY ANN LIEBERT INC PI NEW ROCHELLE PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA SN 0897-7151 J9 J NEUROTRAUM JI J. Neurotrauma PD JUN PY 2011 VL 28 IS 6 BP A48 EP A48 PG 1 WC Critical Care Medicine; Clinical Neurology; Neurosciences SC General & Internal Medicine; Neurosciences & Neurology GA 788PT UT WOS:000292457600158 ER PT J AU Sutherland, DA MacCready, P Banas, NS Smedstad, LF AF Sutherland, David A. MacCready, Parker Banas, Neil S. Smedstad, Lucy F. TI A Model Study of the Salish Sea Estuarine Circulation SO JOURNAL OF PHYSICAL OCEANOGRAPHY LA English DT Article ID COASTAL OCEAN MODEL; JUAN-DE-FUCA; PUGET-SOUND; FORM DRAG; PART I; EXCHANGE; FLOW; FORMULATION; WASHINGTON; TURBULENCE AB A realistic hindcast simulation of the Salish Sea, which encompasses the estuarine systems of Puget Sound, the Strait of Juan de Fuca, and the Strait of Georgia, is described for the year 2006. The model shows moderate skill when compared against hydrographic, velocity, and sea surface height observations over tidal and subtidal time scales. Analysis of the velocity and salinity fields allows the structure and variability of the exchange flow to be estimated for the first time from the shelf into the farthest reaches of Puget Sound. This study utilizes the total exchange flow formalism that calculates volume transports and salt fluxes in an isohaline framework, which is then compared to previous estimates of exchange flow in the region. From this analysis, residence time distributions are estimated for Puget Sound and its major basins and are found to be markedly shorter than previous estimates. The difference arises from the ability of the model and the isohaline method for flux calculations to more accurately estimate the exchange flow. In addition, evidence is found to support the previously observed spring neap modulation of stratification at the Admiralty Inlet sill. However, the exchange flow calculated increases at spring tides, exactly opposite to the conclusion reached from an Eulerian average of observations. C1 [Sutherland, David A.; MacCready, Parker] Univ Washington, Sch Oceanog, Seattle, WA 98195 USA. [Banas, Neil S.] Univ Washington, Appl Phys Lab, Seattle, WA 98105 USA. [Smedstad, Lucy F.] Naval Res Lab, Stennis Space Ctr, MS USA. RP Sutherland, DA (reprint author), NOAA, NW Fisheries Sci Ctr, 2725 Montlake Blvd E, Seattle, WA 98112 USA. EM david.sutherland@noaa.gov RI Banas, Neil/C-8565-2015; OI Banas, Neil/0000-0002-1892-9497; Sutherland, David/0000-0002-2843-8608 FU State of Washington through the University of Washington; National Science Foundation [0849622, 0751683, OCE0942675]; Vetlesen Foundation; National Oceanic and Atmospheric Administration [NA09NOS4780180]; U.S. Navy NAVSEA FX Funding was provided by the State of Washington through the University of Washington Puget Sound Regional Synthesis Model (PRISM) project, and we thank M. Warner, J. Newton, and M. Kawase for leading the data collection part of PRISM. Additional support came from the National Science Foundation Grants 0849622 and 0751683 and the Vetlesen Foundation. This project benefited from many observational programs, but we especially thank B. Hickey for leading the RISE project and sharing the CTD data; E. Dever for the RISE mooring data; and B. Hickey for leading the ECOHAB PNW project, which is supported by the Coastal Ocean Program of the National Oceanic and Atmospheric Administration (NA09NOS4780180) and the National Science Foundation (OCE0942675). The Institute of Ocean Sciences in Canada and the Washington State Department of Ecology generously shared their data, including the Joint Effort to Monitor the Straits (JEMS) led by C. Maloy and J. Newton and cosponsored by Ecology and PRISM. J. Newton, M. Alford, A. Devol, and J. Mickett provided leadership for the Hood Canal Dissolved Oxygen Program (HCDOP), funded through the U.S. Navy NAVSEA. D. Darr provided system administration, and C. Bassin helped archive data. Two anonymous reviewers provided comments that greatly improved the clarity and content of this manuscript. NR 56 TC 49 Z9 49 U1 1 U2 46 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 USA SN 0022-3670 J9 J PHYS OCEANOGR JI J. Phys. Oceanogr. PD JUN PY 2011 VL 41 IS 6 BP 1125 EP 1143 DI 10.1175/2010JPO4540.1 PG 19 WC Oceanography SC Oceanography GA 787VT UT WOS:000292405500006 ER PT J AU Hwang, PA Garcia-Nava, H Ocampo-Torres, FJ AF Hwang, Paul A. Garcia-Nava, Hector Ocampo-Torres, Francisco J. TI Dimensionally Consistent Similarity Relation of Ocean Surface Friction Coefficient in Mixed Seas SO JOURNAL OF PHYSICAL OCEANOGRAPHY LA English DT Article ID WIND-STRESS; DRAG COEFFICIENT; WAVES; ROUGHNESS; PARAMETERIZATION; GENERATION; WAVELENGTH; STATE; FLUX AB Applying wavelength scaling, dimensionally consistent expressions of the ocean surface friction coefficient can be developed for both wind sea and mixed sea in the ocean. For a wind sea with a monopeak wave spectrum, the natural choice of the scaling wavelength is that of the spectral peak component. For a mixed sea with a multipeak spectrum, the peak component in the wind sea portion of the wave spectrum is not a good reference wavelength. A much better scaling wavelength is the weighted average of swell and wind sea following the consideration of equivalent momentum in the wave field. The resulting friction coefficient C(lambda/2) is referenced to the wind speed at one-half of the scaling wavelength U(lambda/2) instead of C(10) referenced to the neutral wind speed at 10-m elevation U(10). Although referencing the wind speed at a fixed elevation such as U(10) is of practical necessity, U(lambda/2) is physically significant as the free-stream velocity in wave-modulated boundary layer flows. A simple procedure to apply the similarity relation of C(lambda/2) to obtain C(10) is described. C1 [Hwang, Paul A.] USN, Res Lab, Remote Sensing Div, Washington, DC 20375 USA. [Garcia-Nava, Hector; Ocampo-Torres, Francisco J.] Ctr Invest Cient & Educ Super Ensenada, Dept Oceanog Fis, Ensenada, Baja California, Mexico. RP Hwang, PA (reprint author), USN, Res Lab, Remote Sensing Div, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM paul.hwang@nrl.navy.mil OI Garcia Nava, Hector/0000-0002-8077-4676 FU Office of Naval Research (NRL) [61153N]; CONACYT [62520, SEP-2003-C02-44718] FX This work is sponsored by the Office of Naval Research (NRL Program Element 61153N) and CONACYT (Project 62520, DirocIOA). The IntOA field experiment was supported by CONACYT (SEP-2003-C02-44718). We are grateful for the insightful comments and suggestions from two anonymous reviewers. NR 33 TC 8 Z9 8 U1 0 U2 4 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 USA SN 0022-3670 J9 J PHYS OCEANOGR JI J. Phys. Oceanogr. PD JUN PY 2011 VL 41 IS 6 BP 1227 EP 1238 DI 10.1175/2011JPO4566.1 PG 12 WC Oceanography SC Oceanography GA 787VT UT WOS:000292405500011 ER PT J AU Seely, JF Szabo, CI Audebert, P Brambrink, E AF Seely, J. F. Szabo, C. I. Audebert, P. Brambrink, E. TI Energetic electron propagation in solid targets driven by the intense electric fields of femtosecond laser pulses SO PHYSICS OF PLASMAS LA English DT Article ID COLLISIONLESS ABSORPTION; PLASMA INTERACTIONS; HOT-ELECTRONS; LIGHT; BEAMS AB An analytical model is used to interpret experimental data on the propagation of energetic electrons perpendicular to and parallel to the propagation direction of intense femtosecond laser pulses that are incident on solid targets. The pulses with approximate to 10(20) W/cm(2) intensity are incident normal onto a gadolinium or tungsten wire embedded in an aluminum substrate, and MeV electrons generated in the focal spot propagate along the laser direction into the irradiated wire. Electrons also propagate laterally from the focal spot through the aluminum substrate and into a dysprosium or hafnium spectator wire at a distance up to 1 mm from the irradiated wire. The ratio of the K shell emission from the spectator and irradiated wires is a measure of the numbers and energies of the MeV electrons propagating parallel to and perpendicular to the intense oscillating electric field of the laser pulse. It is found that the angular distribution of electrons from the focal spot is highly non-isotropic, and approximately twice as many electrons are driven by the electric field toward the spectator wire as into the irradiated wire. This quantitative result is consistent with the qualitative experimental observation that the oscillating electric field of an intense femtosecond laser pulse, when interacting with a heavy metal target, preferentially drives energetic electrons in the electric field direction as compared to perpendicular to the field. (C) 2011 American Institute of Physics. [doi:10.1063/1.3596538] C1 [Seely, J. F.] USN, Res Lab, Washington, DC 20375 USA. [Szabo, C. I.] Artep Inc, Ellicott City, MD 21042 USA. [Audebert, P.; Brambrink, E.] Ecole Polytech, LULI, F-91128 Palaiseau, France. RP Seely, JF (reprint author), USN, Res Lab, 4555 Overlook Ave SW, Washington, DC 20375 USA. EM john.seely@nrl.navy.mil FU Office of Naval Research FX The work at the Naval Research Laboratory was supported by the Office of Naval Research. NR 32 TC 4 Z9 4 U1 0 U2 8 PU AMER INST PHYSICS PI MELVILLE PA 1305 WALT WHITMAN RD, STE 300, MELVILLE, NY 11747-4501 USA SN 1070-664X EI 1089-7674 J9 PHYS PLASMAS JI Phys. Plasmas PD JUN PY 2011 VL 18 IS 6 AR 062702 DI 10.1063/1.3596538 PG 8 WC Physics, Fluids & Plasmas SC Physics GA 786UN UT WOS:000292333500033 ER PT J AU Sotnikov, VI Mudaliar, S Genoni, TC Rose, DV Oliver, BV Mehlhorn, TA AF Sotnikov, V. I. Mudaliar, S. Genoni, T. C. Rose, D. V. Oliver, B. V. Mehlhorn, T. A. TI Shear flow instability in a partially-ionized plasma sheath around a fast-moving vehicle SO PHYSICS OF PLASMAS LA English DT Article ID REENTRY AB The stability of ion acoustic waves in a sheared-flow, partially-ionized compressible plasma sheath around a fast-moving vehicle in the upper atmosphere, is described and evaluated for different flow profiles. In a compressible plasma with shear flow, instability occurs for any velocity profile, not just for profiles with an inflection point. A second-order differential equation for the electrostatic potential of excited ion acoustic waves in the presence of electron and ion collisions with neutrals is derived and solved numerically using a shooting method with boundary conditions appropriate for a finite thickness sheath in contact with the vehicle. We consider three different velocity flow profiles and find that in all cases that neutral collisions can completely suppress the instability. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3596534] C1 [Sotnikov, V. I.; Mudaliar, S.] USAF, Sensors Directorate, Res Lab, Hanscom AFB, MA 01731 USA. [Genoni, T. C.; Rose, D. V.] Voss Sci LLC, Albuquerque, NM 87108 USA. [Oliver, B. V.] Sandia Natl Labs, Albuquerque, NM 87185 USA. [Mehlhorn, T. A.] USN, Res Lab, Washington, DC 20375 USA. RP Sotnikov, VI (reprint author), USAF, Sensors Directorate, Res Lab, Hanscom AFB, MA 01731 USA. FU Sensors Directorate, Air Force Research Laboratory; Air Force Office of Scientific Research FX This work was supported by the Sensors Directorate, Air Force Research Laboratory and by the Air Force Office of Scientific Research. The authors are also thankful to Leonid Rudakov and Michael Keidar for useful discussions. NR 14 TC 4 Z9 4 U1 1 U2 8 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 1070-664X J9 PHYS PLASMAS JI Phys. Plasmas PD JUN PY 2011 VL 18 IS 6 AR 062104 DI 10.1063/1.3596534 PG 8 WC Physics, Fluids & Plasmas SC Physics GA 786UN UT WOS:000292333500005 ER EF