FN Thomson Reuters Web of Science™
VR 1.0
PT J
AU Xu, FJ
Xing, J
Moorman, AC
Gordon, SC
Rupp, LB
Lu, M
Spradling, PR
Teshale, EH
Boscarino, JA
Vijayadeva, V
Schmidt, MA
AF Xu, Fujie
Xing, Jian
Moorman, Anne C.
Gordon, Stuart C.
Rupp, Loralee B.
Lu, Mei
Spradling, Philip R.
Teshale, Eyasu H.
Boscarino, Joseph A.
Vijayadeva, Vinutha
Schmidt, Mark A.
TI FIB4 Score and Gender Predict the Incidence of Hepatocellular Carcinoma
(HCC) among Patients with Chronic Hepatitis C Virus (HCV) Infection:
Chronic Hepatitis Cohort Study (CHeCS)
SO HEPATOLOGY
LA English
DT Meeting Abstract
CT 65th Annual Meeting of the
American-Association-for-the-Study-of-Liver-Diseases
CY NOV 07-11, 2014
CL Boston, MA
SP Amer Assoc Study Liver Dis
C1 [Xu, Fujie; Xing, Jian; Moorman, Anne C.; Spradling, Philip R.; Teshale, Eyasu H.] CDC, Div Viral Hepatitis, Atlanta, GA 30333 USA.
[Gordon, Stuart C.; Rupp, Loralee B.; Lu, Mei] Henry Ford Hlth Syst, Detroit, MI USA.
[Boscarino, Joseph A.] Geisinger Hlth Syst, Danville, PA USA.
[Vijayadeva, Vinutha] Kaiser Permanente Hawaii, Honolulu, HI USA.
[Schmidt, Mark A.] Kaiser Permanente Northwest, Portland, OR USA.
NR 0
TC 1
Z9 1
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0270-9139
EI 1527-3350
J9 HEPATOLOGY
JI Hepatology
PY 2014
VL 60
SU 1
SI SI
MA 1471
BP 905A
EP 905A
PG 1
WC Gastroenterology & Hepatology
SC Gastroenterology & Hepatology
GA AS8EW
UT WOS:000344483804034
ER
PT J
AU Morgan, RL
Blackburn, N
Yartel, AK
Des Jarlais, DC
AF Morgan, Rebecca L.
Blackburn, Natalie
Yartel, Anthony K.
Des Jarlais, Don C.
TI Identifying the disease burden of hepatitis C virus (HCV) infection and
non-injection drug use: a systematic review and meta-analysis of persons
who use drugs but do not inject
SO HEPATOLOGY
LA English
DT Meeting Abstract
CT 65th Annual Meeting of the
American-Association-for-the-Study-of-Liver-Diseases
CY NOV 07-11, 2014
CL Boston, MA
SP Amer Assoc Study Liver Dis
C1 [Morgan, Rebecca L.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Blackburn, Natalie] Oak Ridge Inst Sci & Educ, Atlanta, GA USA.
[Yartel, Anthony K.] Ctr Dis Control & Prevent Fdn, Atlanta, GA USA.
[Des Jarlais, Don C.] Beth Israel Deaconess Med Ctr, New York, NY 10003 USA.
NR 0
TC 0
Z9 0
U1 1
U2 2
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0270-9139
EI 1527-3350
J9 HEPATOLOGY
JI Hepatology
PY 2014
VL 60
SU 1
SI SI
MA 1502
BP 921A
EP 921A
PG 1
WC Gastroenterology & Hepatology
SC Gastroenterology & Hepatology
GA AS8EW
UT WOS:000344483804065
ER
PT J
AU Layden, JE
Phillips, RO
Sarfo, FS
Mora, N
Owusu, DO
Kliethermes, S
Owusu-Ofori, SP
Forbi, J
Opare-Sem, O
Nelson, K
Cooper, R
AF Layden, Jennifer E.
Phillips, Richard O.
Sarfo, Fred S.
Mora, Nallely
Owusu, Dorcas O.
Kliethermes, Stephanie
Owusu-Ofori, Shirley P.
Forbi, Joseph
Opare-Sem, Ohene
Nelson, Kenrad
Cooper, Richard
TI High Rates of HCV Active Infection in a Blood Bank Study in Ghana, West
Africa
SO HEPATOLOGY
LA English
DT Meeting Abstract
CT 65th Annual Meeting of the
American-Association-for-the-Study-of-Liver-Diseases
CY NOV 07-11, 2014
CL Boston, MA
SP Amer Assoc Study Liver Dis
C1 [Layden, Jennifer E.] Loyola Univ, Med Ctr, Maywood, IL 60153 USA.
[Layden, Jennifer E.; Mora, Nallely; Kliethermes, Stephanie; Cooper, Richard] Loyola Univ Chicago, Maywood, IL USA.
[Nelson, Kenrad] Johns Hopkins Univ, Baltimore, MD USA.
[Forbi, Joseph] CDC, Atlanta, GA 30333 USA.
[Phillips, Richard O.; Sarfo, Fred S.; Owusu, Dorcas O.; Owusu-Ofori, Shirley P.; Opare-Sem, Ohene] Komfo Anokye Teaching Hosp, Kumasi, Ghana.
[Phillips, Richard O.; Sarfo, Fred S.; Opare-Sem, Ohene] Kwame Nkrumah Univ Sci & Technol, Kumasi, Ghana.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0270-9139
EI 1527-3350
J9 HEPATOLOGY
JI Hepatology
PY 2014
VL 60
SU 1
SI SI
MA 1512
BP 925A
EP 926A
PG 2
WC Gastroenterology & Hepatology
SC Gastroenterology & Hepatology
GA AS8EW
UT WOS:000344483804075
ER
PT J
AU Layden, JE
Phillips, RO
Sarfo, FS
Owusu, DO
Mora, N
Forbi, J
Kliethermes, S
Owusu-Ofori, SP
Opare-Sem, O
Nelson, K
Cooper, R
AF Layden, Jennifer E.
Phillips, Richard O.
Sarfo, Fred S.
Owusu, Dorcas O.
Mora, Nallely
Forbi, Joseph
Kliethermes, Stephanie
Owusu-Ofori, Shirley P.
Opare-Sem, Ohene
Nelson, Kenrad
Cooper, Richard
TI Evidence for Multiple Transmission Pathways and Geographic Variation of
HCV infection in Ghana, West Africa
SO HEPATOLOGY
LA English
DT Meeting Abstract
CT 65th Annual Meeting of the
American-Association-for-the-Study-of-Liver-Diseases
CY NOV 07-11, 2014
CL Boston, MA
SP Amer Assoc Study Liver Dis
C1 [Layden, Jennifer E.] Loyola Univ, Med Ctr, Maywood, IL 60153 USA.
[Layden, Jennifer E.; Mora, Nallely; Kliethermes, Stephanie] Loyola Univ Chicago, Maywood, IL USA.
[Forbi, Joseph] CDC, Atlanta, GA 30333 USA.
[Nelson, Kenrad] Johns Hopkins Univ, Baltimore, MD USA.
[Phillips, Richard O.; Sarfo, Fred S.; Owusu, Dorcas O.; Owusu-Ofori, Shirley P.; Opare-Sem, Ohene; Cooper, Richard] Komfo Anokye Teaching Hosp, Kumasi, Ghana.
[Phillips, Richard O.; Sarfo, Fred S.; Opare-Sem, Ohene; Cooper, Richard] Kwame Nkrumah Univ Sci & Technol, Kumasi, Ghana.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0270-9139
EI 1527-3350
J9 HEPATOLOGY
JI Hepatology
PY 2014
VL 60
SU 1
SI SI
MA 1540
BP 939A
EP 939A
PG 1
WC Gastroenterology & Hepatology
SC Gastroenterology & Hepatology
GA AS8EW
UT WOS:000344483804103
ER
PT J
AU Teshale, EH
Xing, J
Holmberg, SD
Moorman, AC
Gordon, SC
Rupp, LB
Lu, M
Spradling, P
Boscarino, JA
Vijayadeva, V
Schmidt, MA
Xu, FJ
AF Teshale, Eyasu H.
Xing, Jian
Holmberg, Scott D.
Moorman, Anne C.
Gordon, Stuart C.
Rupp, Loralee B.
Lu, Mei
Spradling, Philip
Boscarino, Joseph A.
Vijayadeva, Vinutha
Schmidt, Mark A.
Xu, Fujie
TI Increased all-cause hospitalization among hepatitis C virus
(HCV)-infected persons: the Chronic Hepatitis Cohort Study (CHeCS),
2006-2010
SO HEPATOLOGY
LA English
DT Meeting Abstract
CT 65th Annual Meeting of the
American-Association-for-the-Study-of-Liver-Diseases
CY NOV 07-11, 2014
CL Boston, MA
SP Amer Assoc Study Liver Dis
C1 [Teshale, Eyasu H.; Xing, Jian; Holmberg, Scott D.; Moorman, Anne C.; Spradling, Philip; Xu, Fujie] CDC, Atlanta, GA 30333 USA.
[Gordon, Stuart C.; Rupp, Loralee B.; Lu, Mei] Henry Ford Hlth Syst, Detroit, MI USA.
[Boscarino, Joseph A.] Geisinger Hlth Systme, Danville, PA USA.
[Vijayadeva, Vinutha] Kaiser Permanente, Hawai, HI USA.
[Schmidt, Mark A.] Kaiser Permanente Northwest, Portland, OR USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0270-9139
EI 1527-3350
J9 HEPATOLOGY
JI Hepatology
PY 2014
VL 60
SU 1
SI SI
MA 1569
BP 953A
EP 954A
PG 2
WC Gastroenterology & Hepatology
SC Gastroenterology & Hepatology
GA AS8EW
UT WOS:000344483804132
ER
PT J
AU Lau, D
Ganova-Raeva, L
Chung, RT
Johnson, G
Chang, KM
Lisker-Melman, M
Shaikh, OS
Janssen, HL
Wahed, AS
Lok, AS
AF Lau, Daryl
Ganova-Raeva, Lilia
Chung, Raymond T.
Johnson, Geoffrey
Chang, Kyong-Mi
Lisker-Melman, Mauricio
Shaikh, Obaid S.
Janssen, Harry L.
Wahed, Abdus S.
Lok, Anna S.
TI Prevalence of Precore and Dual Basal Core Promoter HBV Variants in a
Racially Diverse Cohort of Patients with Chronic HBV Infection in North
America
SO HEPATOLOGY
LA English
DT Meeting Abstract
CT 65th Annual Meeting of the
American-Association-for-the-Study-of-Liver-Diseases
CY NOV 07-11, 2014
CL Boston, MA
SP Amer Assoc Study Liver Dis
C1 [Lau, Daryl] Harvard Univ, Sch Med, BIDMC, Boston, MA USA.
[Ganova-Raeva, Lilia] CDC, Atlanta, GA 30333 USA.
[Chung, Raymond T.] Harvard Univ, Sch Med, MGH, Boston, MA USA.
[Johnson, Geoffrey; Shaikh, Obaid S.; Wahed, Abdus S.] Univ Pittsburgh, Pittsburgh, PA USA.
[Chang, Kyong-Mi] Philadelphia VAMC, Philadelphia, PA USA.
[Chang, Kyong-Mi] Univ Penn, Philadelphia, PA 19104 USA.
[Lisker-Melman, Mauricio] Washington Univ, Sch Med, St Louis, MO USA.
[Janssen, Harry L.] Toronto Western Hosp, Univ Hlth Network, Toronto, ON M5T 2S8, Canada.
[Lok, Anna S.] Univ Michigan, Ann Arbor, MI 48109 USA.
NR 0
TC 1
Z9 1
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0270-9139
EI 1527-3350
J9 HEPATOLOGY
JI Hepatology
PY 2014
VL 60
SU 1
SI SI
MA 1605
BP 970A
EP 971A
PG 3
WC Gastroenterology & Hepatology
SC Gastroenterology & Hepatology
GA AS8EW
UT WOS:000344483804168
ER
PT J
AU Bruce, M
Ching, L
Gounder, PP
Bulkow, L
Spradling, PR
Snowball, M
Negus, S
McMahon, BJ
AF Bruce, Michael
Ching, Lance
Gounder, Prabhu P.
Bulkow, Lisa
Spradling, Philip R.
Snowball, Mary
Negus, Susan
McMahon, Brian J.
TI Epidemiology of Hepatitis B Virus Infection according to Genotype in
Alaska Native People
SO HEPATOLOGY
LA English
DT Meeting Abstract
CT 65th Annual Meeting of the
American-Association-for-the-Study-of-Liver-Diseases
CY NOV 07-11, 2014
CL Boston, MA
SP Amer Assoc Study Liver Dis
C1 [Bruce, Michael; Gounder, Prabhu P.; Bulkow, Lisa] CDC, Arctic Invest Program, Anchorage, AK USA.
[Ching, Lance] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA.
[Spradling, Philip R.] CDC, Epidemiol & Surveillance Branch, Div Viral Hepatitis, Atlanta, GA 30333 USA.
[Snowball, Mary; Negus, Susan; McMahon, Brian J.] Alaska Native Tribal Hlth Consortium, Liver Dis & Hepatitis Program, Anchorage, AK USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0270-9139
EI 1527-3350
J9 HEPATOLOGY
JI Hepatology
PY 2014
VL 60
SU 1
SI SI
MA 1610
BP 973A
EP 973A
PG 1
WC Gastroenterology & Hepatology
SC Gastroenterology & Hepatology
GA AS8EW
UT WOS:000344483804173
ER
PT J
AU Gounder, PP
Bulkow, L
Snowball, M
Negus, S
Spradling, PR
Bruce, M
McMahon, BJ
AF Gounder, Prabhu P.
Bulkow, Lisa
Snowball, Mary
Negus, Susan
Spradling, Philip R.
Bruce, Michael
McMahon, Brian J.
TI Hepatocellular Carcinoma Risk By Genotype Among Hepatitis B Virus
Infected Alaska Native Persons Who Are Below the Age For Which
Guidelines Recommend HCC Surveillance. A Population-Based Retrospective
Cohort Study
SO HEPATOLOGY
LA English
DT Meeting Abstract
CT 65th Annual Meeting of the
American-Association-for-the-Study-of-Liver-Diseases
CY NOV 07-11, 2014
CL Boston, MA
SP Amer Assoc Study Liver Dis
C1 [Gounder, Prabhu P.; Bulkow, Lisa; Bruce, Michael] Ctr Dis Control & Prevent, Arctic Invest Program, Anchorage, AK USA.
[Snowball, Mary; Negus, Susan] Alaska Native Tribal Hlth Consortium, Liver Dis & Hepatitis Program, Anchorage, AK USA.
[Spradling, Philip R.; McMahon, Brian J.] Ctr Dis Control & Prevent, Div Viral Hepatitis, Atlanta, GA USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0270-9139
EI 1527-3350
J9 HEPATOLOGY
JI Hepatology
PY 2014
VL 60
SU 1
SI SI
MA 1614
BP 975A
EP 975A
PG 1
WC Gastroenterology & Hepatology
SC Gastroenterology & Hepatology
GA AS8EW
UT WOS:000344483804177
ER
PT J
AU Xu, FJ
Leidner, AJ
Tong, X
Holmberg, SD
AF Xu, Fujie
Leidner, Andrew J.
Tong, Xin
Holmberg, Scott D.
TI Estimating the Number of Patients with Chronic Hepatitis C Infection
According to Liver Fibrosis Stage in the United States
SO HEPATOLOGY
LA English
DT Meeting Abstract
CT 65th Annual Meeting of the
American-Association-for-the-Study-of-Liver-Diseases
CY NOV 07-11, 2014
CL Boston, MA
SP Amer Assoc Study Liver Dis
C1 [Xu, Fujie; Leidner, Andrew J.; Tong, Xin; Holmberg, Scott D.] CDC, Div Viral Hepatitis, Atlanta, GA 30333 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0270-9139
EI 1527-3350
J9 HEPATOLOGY
JI Hepatology
PY 2014
VL 60
SU 1
SI SI
MA 1757
BP 1044A
EP 1045A
PG 2
WC Gastroenterology & Hepatology
SC Gastroenterology & Hepatology
GA AS8EW
UT WOS:000344483804319
ER
PT B
AU Maslanka, SE
AF Maslanka, Susan E.
BE Foster, KA
TI Botulism as a Disease of Humans
SO MOLECULAR ASPECTS OF BOTULINUM NEUROTOXIN, VOL 4
SE Current Topics in Neurotoxicity
LA English
DT Article; Book Chapter
DE Botulinum neurotoxin; Botulism; Foodborne botulism; Wound botulism;
Infant botulism; Iatrogenic; Toxinfection
ID A FOODBORNE BOTULISM; CLOSTRIDIUM-BOTULINUM; WOUND BOTULISM; INFANT
BOTULISM; INTESTINAL COLONIZATION; LABORATORY DIAGNOSIS; IATROGENIC
BOTULISM; ADVERSE EVENTS; CEREBRAL-PALSY; FERMENTED TOFU
AB Human botulism presents in several different forms which provide unique challenges to public health. Foodborne botulism, while still an issue with home-processed foods, is sometimes associated with restaurants and commercially produced (particularly chilled) foods. The diversity of food products available to consumers, which are widely distributed, requires an integrated, multiagency response approach to contain, evaluate and develop appropriate prevention measures. Wound and adult intestinal toxemia cases are difficult to confirm, and so the total illness burden is likely unknown. Infant botulism highlights the diversity of the neurotoxin-producing Clostridium sp. and associated toxins which can cause botulism worldwide. Finally, an astounding number of adverse events associated with toxin injections remind us of the hazards of botulinum toxin even as its therapeutic benefits expand.
C1 Ctr Dis Control & Prevent CDC, Atlanta, GA 30333 USA.
RP Maslanka, SE (reprint author), Ctr Dis Control & Prevent CDC, Atlanta, GA 30333 USA.
EM sht5@cdc.gov
NR 127
TC 1
Z9 1
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES
BN 978-1-4614-9454-6; 978-1-4614-9453-9
J9 CURR TOP NEUROTOX
PY 2014
VL 4
BP 259
EP 289
DI 10.1007/978-1-4614-9454-6_12
D2 10.1007/978-1-4614-9454-6
PG 31
WC Biochemistry & Molecular Biology; Neurosciences; Toxicology
SC Biochemistry & Molecular Biology; Neurosciences & Neurology; Toxicology
GA BB6GC
UT WOS:000344751500012
ER
PT S
AU Fu, PC
Tolentino, H
Franzke, LH
AF Fu, Paul C., Jr.
Tolentino, Herman
Franzke, Laura H.
BE Magnuson, JA
Fu, PC
TI Evaluation for Public Health Informatics
SO PUBLIC HEALTH INFORMATICS AND INFORMATION SYSTEMS, 2ND EDITION
SE Health Informatics Series
LA English
DT Article; Book Chapter
DE Evaluation; Formative evaluation; Summative evaluation; Mental models;
Evaluation frameworks; Evaluation strategies; Information value cycle;
Data-information-system-context rings; Mental models; Information Value
Cycle; Data-Information System-Context Rings; CDC Six-Step Evaluation
Framework
ID EVALUATION FRAMEWORKS; MEDICAL INFORMATICS; NETWORK ANALYSIS; SYSTEMS;
CARE; IMPLEMENTATION; TECHNOLOGIES; CHALLENGES; MANAGEMENT; QUALITY
AB Evaluation is the application of specific criteria to determine the value or merit of the object of the study. Ensuring that public health information systems (ISs) and programs are managed wisely is essential. Evaluation answers the question of "why" a system is necessary, by collecting the data and performing the analysis needed to make determinations of efficiency and effectiveness and is a critical component to any public health informatics (PHI) project. Evaluation should occur at all stages of a PHI project. By using a combination of formative and summative evaluation, a well-designed plan provides key data to stakeholders that allow for informed decision-making about continuing, replacing, enhancing or retiring a public health IS. The design of the evaluation plan begins with identifying a mental model (e.g., information value cycle or data-information system-context-rings) from which to view the project and the evaluation objectives and determine what to evaluate. Conceptual frameworks, evaluation strategies, and methodology toolkits help define how the evaluation plan is developed and executed. A comprehensive program (e.g., the Centers for Disease Control and Prevention's six-step evaluation framework) provides an example of an evaluation template.
C1 [Fu, Paul C., Jr.] Univ Calif Los Angeles, David Geffen Sch Med, Torrance, CA 90509 USA.
[Fu, Paul C., Jr.] Los Angeles Cty Harbor UCLA Med Ctr, UCLA Fielding Sch Publ Hlth, Torrance, CA 90509 USA.
[Tolentino, Herman; Franzke, Laura H.] Ctr Dis Control & Prevent CDC, Sci Educ & Profess Dev Program Off, Atlanta, GA 30333 USA.
RP Fu, PC (reprint author), Univ Calif Los Angeles, David Geffen Sch Med, 1000 W Carson St,Bldg E-4, Torrance, CA 90509 USA.
EM pfu@labiomed.org; cke1@cdc.gov; lfranzke@cdc.gov
NR 44
TC 0
Z9 0
U1 1
U2 1
PU SPRINGER
PI NEW YORK
PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES
SN 1431-1917
BN 978-1-4471-4237-9; 978-1-4471-4236-2
J9 HEALTH INFORM SER
PY 2014
BP 233
EP 254
DI 10.1007/978-1-4471-4237-9_13
D2 10.1007/978-1-4471-4237-9
PG 22
WC Computer Science, Information Systems; Computer Science,
Interdisciplinary Applications; Medical Informatics
SC Computer Science; Medical Informatics
GA BB5NB
UT WOS:000343972300015
ER
PT S
AU Rothwell, CJ
Freedman, MA
Weed, JA
AF Rothwell, Charles J.
Freedman, Mary Anne
Weed, James A.
BE Magnuson, JA
Fu, PC
TI The National Vital Statistics System
SO PUBLIC HEALTH INFORMATICS AND INFORMATION SYSTEMS, 2ND EDITION
SE Health Informatics Series
LA English
DT Article; Book Chapter
DE Vital statistics; National Vital Statistics System; Model State Vital
Statistics Act; International Classification of Disease; Vital
Statistics Cooperative Program; National Center for Health Statistics;
National Association for Public Health Statistics and Information
Systems; US Standard Certificates; US Standard Reports; Interstate
record exchange; Electronic birth registration; Electronic death
registration; Mortality surveillance; State and Territorial Exchange of
Vital Events; Electronic Verification of Vital Events
AB The vital statistics system in the United States has always recognized the importance of collecting information about public health. Today, the national vital statistics system in the US is a major cooperative effort between the states and federal agencies. The Vital Statistics Cooperative Program provides for collection of records of births, deaths, marriages, and other events on a national level. Moreover, increasing adoption of modern technology for record keeping and data exchange has resulted in faster and more accurate vital statistics reports. State data, supplemented by surveys administered by the National Center for Health Statistics within the Centers for Disease Control and Prevention, provide fundamental information for use in the arena of public policy and public health practice.
In this chapter, we will describe the history of vital statistics in the United States, and examine what data is collected and how collection methods have changed over time. In addition, we will examine the complex relationship between the collection of data at the local and state levels and the aggregation and analysis of the data by the National Center for Health Statistics. This will set the stage for a discussion of the components and uses of the present National Vital Statistics System, including an assessment of the challenges and solutions that the twenty first century presents.
C1 [Rothwell, Charles J.; Weed, James A.] CDC, Natl Ctr Hlth Stat, HHS, Hyattsville, MD 20782 USA.
[Freedman, Mary Anne] Poinciana Consulting LLC, Venice, FL 34293 USA.
RP Rothwell, CJ (reprint author), CDC, Natl Ctr Hlth Stat, HHS, 3311 Toledo Rd, Hyattsville, MD 20782 USA.
EM crothwell@cdc.gov; maryannefreedman@comcast.net; whidbey@comcast.net
NR 13
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES
SN 1431-1917
BN 978-1-4471-4237-9; 978-1-4471-4236-2
J9 HEALTH INFORM SER
PY 2014
BP 309
EP 327
DI 10.1007/978-1-4471-4237-9_17
D2 10.1007/978-1-4471-4237-9
PG 19
WC Computer Science, Information Systems; Computer Science,
Interdisciplinary Applications; Medical Informatics
SC Computer Science; Medical Informatics
GA BB5NB
UT WOS:000343972300019
ER
PT S
AU Garrett, NY
AF Garrett, Nedra Y.
BE Magnuson, JA
Fu, PC
TI Setting National Policies and Standards for Immunization Information
Systems
SO PUBLIC HEALTH INFORMATICS AND INFORMATION SYSTEMS, 2ND EDITION
SE Health Informatics Series
LA English
DT Article; Book Chapter
DE Immunization information systems; Standards; National; Policies;
Vaccines; Decision support; Adverse events; Point of clinical care
ID CHILDHOOD IMMUNIZATION
AB Immunization Information Systems (IIS) are confidential, computerized, population-based systems that collect and consolidate vaccination data from vaccination providers and provide important tools for designing and sustaining effective immunization strategies (National Center for Immunization and Respiratory Diseases, Immunization information systems [Internet]. Atlanta: Centers for Disease Control and Prevention, 2013). At the point of clinical care, an IIS can provide consolidated immunization histories for use by a vaccination provider in determining appropriate client vaccinations. The Centers for Disease Control and Prevention (CDC), in collaboration with key stakeholders, works to ensure IIS are responsive to the needs of the Immunization programs at all levels of government and that these systems take advantage of advances in technology and are aligned with national data and exchange standards. CDC's Immunization program publishes IIS Minimum Functional Standards that provides a framework for the development of IIS through 2017 that describes specific standards that address the IIS programmatic goals, and operational and technical capacities that all IIS should achieve by the end of 2017. These standards were developed through a consensus process from a variety of IIS managers and technical experts from across the US. Several examples of data, standards and systems are provided for each functional standard. This chapter also will examine various policy and technology drivers such as the Centers for Medicare & Medicaid Services (CMS) EHR Incentive Programs' Meaningful Use criteria.
C1 Ctr Dis Control & Prevent, Div Informat Practice Policy & Coordinat, Atlanta, GA 30333 USA.
RP Garrett, NY (reprint author), Ctr Dis Control & Prevent, Div Informat Practice Policy & Coordinat, 1600 Clifton Rd,NE MS E76, Atlanta, GA 30333 USA.
EM ngarrett@cdc.gov
NR 27
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES
SN 1431-1917
BN 978-1-4471-4237-9; 978-1-4471-4236-2
J9 HEALTH INFORM SER
PY 2014
BP 355
EP 371
DI 10.1007/978-1-4471-4237-9_19
D2 10.1007/978-1-4471-4237-9
PG 17
WC Computer Science, Information Systems; Computer Science,
Interdisciplinary Applications; Medical Informatics
SC Computer Science; Medical Informatics
GA BB5NB
UT WOS:000343972300021
ER
PT S
AU Tolentino, H
Sangareddy, SRP
Pepper, C
Magnuson, JA
AF Tolentino, Herman
Sangareddy, Sridhar R. Papagari
Pepper, Catherine
Magnuson, J. A.
BE Magnuson, JA
Fu, PC
TI Case-Based Learning in Public Health Informatics
SO PUBLIC HEALTH INFORMATICS AND INFORMATION SYSTEMS, 2ND EDITION
SE Health Informatics Series
LA English
DT Article; Book Chapter
DE Problem-based learning; Case-based learning; Information Value Cycle;
Case study; Complex adaptive systems; Electronic laboratory reporting;
Clinical laboratory information systems
ID POPULATION HEALTH
AB The public health landscape is undergoing profound changes, including rapid advances in technology, increasing use of electronic health records, and health reform. Improving population health requires knowledge and skills in managing and working within the adaptive complexity of underlying societal structures and functions. These advances in technology, and profound changes within these structures and functions, introduce enormous opportunities for creating efficiencies and economies of scale, not simply for improving public health practice, but for learning as well. Finding informatics solutions to cross-cutting information needs, while solving complex health problems, requires cross-disciplinary education, research, and practice.
Approaches to overcoming these challenges should address the complexity of problems within both the work and learning environments. These problem-based approachevs build skills in collaborative problem solving, critical thinking, systems thinking and lifelong learning. This chapter discusses case-based learning (CBL) as one of the methods for problem-based learning (PBL) and is aimed at the student of public health informatics (PHI) exploring this topic for the first time. The chapter concludes with a student exercise developed for fellows in the CDC Public Health Informatics Fellowship Program.
C1 [Tolentino, Herman] Ctr Dis Control & Prevent CDC, Publ Hlth Informat Fellowship Program, Sci Educ & Profess Dev Program Off, Atlanta, GA 30333 USA.
[Sangareddy, Sridhar R. Papagari] Ctr Dis Control & Prevent, Publ Hlth Informat Fellowship Program, Atlanta, GA 30333 USA.
[Pepper, Catherine] Texas A&M Univ, Med Sci Lib, Round Rock, TX 78665 USA.
[Magnuson, J. A.] Oregon Hlth & Sci Univ, Dept Med Informat & Clin Epidemiol, Portland, OR 97239 USA.
[Tolentino, Herman] Ctr Dis Control & Prevent CDC, Sci Educ & Profess Dev Program Off, Atlanta, GA 30333 USA.
RP Tolentino, H (reprint author), Ctr Dis Control & Prevent CDC, Publ Hlth Informat Fellowship Program, Sci Educ & Profess Dev Program Off, 1600 Clifton Rd NE,Mailstop E-92, Atlanta, GA 30333 USA.
EM htolentino@cdc.gov; spapagarisangareddy@cdc.gov; cpepper@tamu.edu;
jamagnuson@gmail.com
NR 30
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES
SN 1431-1917
BN 978-1-4471-4237-9; 978-1-4471-4236-2
J9 HEALTH INFORM SER
PY 2014
BP 489
EP 510
DI 10.1007/978-1-4471-4237-9_25
D2 10.1007/978-1-4471-4237-9
PG 22
WC Computer Science, Information Systems; Computer Science,
Interdisciplinary Applications; Medical Informatics
SC Computer Science; Medical Informatics
GA BB5NB
UT WOS:000343972300027
ER
PT S
AU Richards, J
Douglas, G
Fraser, HSF
AF Richards, Janise
Douglas, Gerry
Fraser, Hamish S. F.
BE Magnuson, JA
Fu, PC
TI Perspectives on Global Public Health Informatics
SO PUBLIC HEALTH INFORMATICS AND INFORMATION SYSTEMS, 2ND EDITION
SE Health Informatics Series
LA English
DT Article; Book Chapter
DE Global health; Global health informatics; OpenMRS; PEPFAR; HIV/AIDS;
Malawi; Rwanda; EHR; Low income; Resource-constrained
ID NEGLECTED TROPICAL DISEASES; MEDICAL-RECORD; HIV TREATMENT; SYSTEMS;
CARE
AB Public health professionals' functions are rapidly expanding beyond their countries' borders. Many academic centers are recognizing the importance of global health and are creating programs to train students to meet this growing demand. Global health centers and institutes also are being created to focus on the research and programmatic efforts needed to understand the burden of disease worldwide, as well as the financial, political, medical, policy, workforce, and infrastructure issues surrounding any solutions. Due to this emerging interest by the public health community, we need to understand where the intersection between global health and informatics occurs. For many years, the promise of what technology can do to alleviate suffering and support disease surveillance and other public health activities took precedence over understanding the environment in which the technology has to function. People and their participation in the implementation of the technological solution are critical for success. In resource-poor environments, the deployment of technological solutions faces other challenges for success. Lack of stable electrical power, availability of Internet connections, and a workforce that can support the information technology remain barriers to successful implementation. Yet, through experiences in the implementation of information technology as supported by international donors and the US President's Emergency Plan for AIDS Relief, lessons are being learned to move forward towards the benefits that global health informatics can bring.
C1 [Richards, Janise] Ctr Dis Control & Prevent, Div Global HIV AIDS, Ctr Global Hlth, Atlanta, GA 30333 USA.
[Douglas, Gerry] Univ Pittsburgh, Dept Biomed Informat, Ctr Hlth Informat Underserved, Pittsburgh, PA 15206 USA.
[Fraser, Hamish S. F.] Brigham & Womens Hosp, Div Global Hlth Equity, Dept Med, Boston, MA 02115 USA.
RP Richards, J (reprint author), Ctr Dis Control & Prevent, Div Global HIV AIDS, Ctr Global Hlth, 1600 Clifton Rd,M-S E30, Atlanta, GA 30333 USA.
EM jrichards@cdc.gov; gdouglas@pitt.edu; hamish_fraser@hms.harvard.edu
RI Fraser, Hamish/E-3773-2013
NR 38
TC 0
Z9 0
U1 0
U2 1
PU SPRINGER
PI NEW YORK
PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES
SN 1431-1917
BN 978-1-4471-4237-9; 978-1-4471-4236-2
J9 HEALTH INFORM SER
PY 2014
BP 619
EP 644
DI 10.1007/978-1-4471-4237-9_31
D2 10.1007/978-1-4471-4237-9
PG 26
WC Computer Science, Information Systems; Computer Science,
Interdisciplinary Applications; Medical Informatics
SC Computer Science; Medical Informatics
GA BB5NB
UT WOS:000343972300033
ER
PT J
AU Tack, DM
Holman, RC
Folkema, AM
Mehal, JM
Blanton, JD
Sejvar, JJ
AF Tack, Danielle M.
Holman, Robert C.
Folkema, Arianne M.
Mehal, Jason M.
Blanton, Jesse D.
Sejvar, James J.
TI Trends in Encephalitis-Associated Deaths in the United States, 1999-2008
SO NEUROEPIDEMIOLOGY
LA English
DT Article
DE Encephalitis; Mortality; Unspecified encephalitis
ID WEST-NILE-VIRUS; NERVOUS-SYSTEM INFECTIONS; EPIDEMIOLOGY; MANAGEMENT;
HIV
AB Background: While encephalitis may be caused by numerous infectious, immune and toxic processes, the etiology often remains unknown. Methods: We analyzed multiple cause-of-death mortality data during 1999-2008 for the USA, using the 10th revision of International Classification of Diseases codes for encephalitis, listed anywhere on the death record, including 'specified' and 'unspecified' encephalitis. Annual and average annual age-adjusted and age-specific death rates were calculated. Results: For 1999-2008, 12,526 encephalitis-associated deaths were reported with 68.5% as unspecified encephalitis. The average annual age-adjusted encephalitis-associated death rate was 4.3 per 1 million persons, 1.3 for specified and 2.9 for unspecified encephalitis. Annual encephalitis-associated death rates had a significant downward trend (p < 0.01). The most common specified encephalitis deaths were herpesviral encephalitis (36.7%), Toxoplasma meningoencephalitis (27.8%) and Listeria meningitis/meningoencephaltis (6.8%). HIV was colisted with 15.0% of encephalitis-associated deaths, 58.4% of these with a specified code. Conclusion: Encephalitis-associated death rates decreased during 1999-2008, and herpesvirus was the most commonly identified infectious agent associated with encephalitis deaths. The high proportion of unspecified encephalitis deaths highlights the continued challenge of laboratory confirmation for causes of encephalitis and the importance of monitoring trends to assess the impact of new diagnostics and guide potential interventions. (C) 2014 S. Karger AG, Basel
C1 [Tack, Danielle M.] Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA.
[Tack, Danielle M.; Holman, Robert C.; Folkema, Arianne M.; Mehal, Jason M.; Blanton, Jesse D.; Sejvar, James J.] Ctr Dis Control & Prevent, Div High Consequence Pathogens & Pathol, Atlanta, GA 30333 USA.
RP Sejvar, JJ (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd,Mailstop A-30, Atlanta, GA 30333 USA.
EM zea3@cdc.gov
FU Centers for Disease Control and Prevention
FX We would like to thank Neil Vora at CDC Poxvirus and Rabies Branch for
support of this project. All work was supported by the Centers for
Disease Control and Prevention.
NR 28
TC 6
Z9 6
U1 0
U2 3
PU KARGER
PI BASEL
PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND
SN 0251-5350
EI 1423-0208
J9 NEUROEPIDEMIOLOGY
JI Neuroepidemiology
PY 2014
VL 43
IS 1
BP 1
EP 8
DI 10.1159/000362688
PG 8
WC Public, Environmental & Occupational Health; Clinical Neurology
SC Public, Environmental & Occupational Health; Neurosciences & Neurology
GA AS0GG
UT WOS:000343955500001
PM 24968857
ER
PT J
AU Kilinc, FS
Monaghan, WD
Powell, JB
AF Kilinc, F. Selcen
Monaghan, William D.
Powell, Jeffrey B.
TI A Review of Mine Rescue Ensembles for Underground Coal Mining in the
United States
SO JOURNAL OF ENGINEERED FIBERS AND FABRICS
LA English
DT Review
DE mine rescue ensemble; protective clothing; personal protective
equipment; fire fighter; mining
ID STANDARD; STRESS; STRAIN
AB The mining industry is among the top ten industries nationwide with high occupational injury and fatality rates, and mine rescue response may be considered one of the most hazardous activities in mining operations. In the aftermath of an underground mine fire, explosion or water inundation, specially equipped and trained teams have been sent underground to fight fires, rescue entrapped miners, test atmospheric conditions, investigate the causes of the disaster, or recover the dead. Special personal protective ensembles are used by the team members to improve the protection of rescuers against the hazards of mine rescue and recovery. Personal protective ensembles used by mine rescue teams consist of helmet, cap lamp, hood, gloves, protective clothing, boots, kneepads, facemask, breathing apparatus, belt, and suspenders.
While improved technology such as wireless warning and communication systems, lifeline pulleys, and lighted vests have been developed for mine rescuers over the last 100 years, recent research in this area of personal protective ensembles has been minimal due to the trending of reduced exposure of rescue workers. In recent years, the exposure of mine rescue teams to hazardous situations has been changing. However, it is vital that members of the teams have the capability and proper protection to immediately respond to a wide range of hazardous situations. Currently, there are no minimum requirements, best practice documents, or nationally recognized consensus standards for protective clothing used by mine rescue teams in the United States (U. S.). The following review provides a summary of potential issues that can be addressed by rescue teams and industry to improve potential exposures to rescue team members should a disaster situation occur. However, the continued trending in the mining industry toward non-exposure to potential hazards for rescue workers should continue to be the primary goal. To assist in continuing this trend, the mining industry and regulatory agencies have been more restrictive by requiring additional post disaster information regarding atmospheric conditions and other hazards before exposing rescue workers and others in the aftermath of a mine disaster. In light of some of the more recent mine rescuer fatalities such as the Crandall Canyon Mine and Jim Walters Resources in the past years, the direction of reducing exposure is preferred. This review provides a historical perspective on ensembles used during mine rescue operations and summarizes environmental hazards, critical elements of mine rescue ensembles, and key problems with these elements. This study also identifies domains for improved mine rescue ensembles. Furthermore, field observations from several coal mine rescue teams were added to provide the information on the currently used mine rescue ensembles in the U.S.
C1 [Kilinc, F. Selcen; Monaghan, William D.; Powell, Jeffrey B.] NIOSH, Ctr Dis Control & Prevent, Natl Personal Protect Technol Lab, Pittsburgh, PA 15236 USA.
RP Kilinc, FS (reprint author), NIOSH, Ctr Dis Control & Prevent, Natl Personal Protect Technol Lab, 626 Cochrans Mill Rd Bldg T403, Pittsburgh, PA 15236 USA.
EM fselcen@gmail.com
FU Intramural CDC HHS [CC999999]
NR 36
TC 0
Z9 0
U1 3
U2 8
PU INDA
PI CARY
PA PO BOX 1288, CARY, NC 27512-1288 USA
SN 1558-9250
J9 J ENG FIBER FABR
JI J. Eng. Fiber Fabr.
PY 2014
VL 9
IS 1
BP 174
EP 185
PG 12
WC Materials Science, Textiles
SC Materials Science
GA AR7GI
UT WOS:000343747100020
PM 27065231
ER
PT J
AU Ervin, RB
Dye, BA
AF Ervin, R. Bethene
Dye, Bruce A.
TI Associations Between Posterior Functional Contacts and Nutrient Intakes
and Serum Nutrient Values Among Adults in NHANES 2003-2004
SO ORAL HEALTH & PREVENTIVE DENTISTRY
LA English
DT Article
DE dietary recall; functional contacts; NHANES; serum nutrients
ID ORAL-HEALTH COMPONENT; US ADULTS; NUTRITIONAL-STATUS; QUALITY-ASSURANCE;
NATIONAL-HEALTH; NATURAL TEETH; OLDER-ADULTS; PEOPLE; DIET; FOOD
AB Purpose: To examine the associations between the numbers of posterior functional contacts (FCs) and selected nutrient intakes and serum/plasma nutrient values in 3,554 adults 25 years of age and older from the 2003-2004 National Health and Nutrition Examination Survey (NHANES).
Materials and Methods: FCs consist of the number of zones of contact between the maxillary and opposing mandibular posterior teeth when the maxillary and mandibular posterior teeth are together. There were 16 possible zones of contact. Nutrient intakes were calculated from one 24-h dietary recall and selected nutritional biochemistries were measured. Multivariate linear regression was used to examine the association between the numbers of FCs and nutrient intakes or serum/plasma nutrient values, controlling for potential confounding variables.
Results: Males with 6 or more FCs had higher vitamin A (p < 0.05), C (p < 0.05), E (p < 0.01) and B-6 intakes (p < 0.05) than those with 5 or fewer FCs. Females with 6 or more FCs had higher dietary fiber (p < 0.05), vitamin E (p < 0.05) and folate intakes (p < 0.05) than those with 5 or fewer FCs. Males and females with 6 or more FCs had higher serum beta-carotene than those with 5 or fewer FCs (p < 0.05 and p < 0.001, respectively). Males with 6 or more FCs had higher serum folate levels than those with 5 or fewer FCs (p < 0.01), and females with 6 or more FCs had higher serum vitamin C levels than those with 5 or fewer FCs (p < 0.05).
Conclusions: Dietary intakes and serum levels of certain nutrients differ by the number of FCs present.
C1 [Ervin, R. Bethene] Ctr Dis Control & Prevent, Natl Ctr Hlth Stat, Div Hlth & Nutr Examinat Stat, Hyattsville, MD 20782 USA.
[Dye, Bruce A.] Ctr Dis Control & Prevent, Natl Ctr Hlth Stat, Div Hlth Examinat Stat, Hyattsville, MD 20782 USA.
RP Dye, BA (reprint author), Natl Ctr Hlth Stat, Div Hlth Examinat Stat, 3311 Toledo Rd,Room 4416, Hyattsville, MD 20782 USA.
EM bfd1@cdc.gov
NR 23
TC 0
Z9 0
U1 0
U2 2
PU QUINTESSENCE PUBLISHING CO INC
PI HANOVER PARK
PA 4350 CHANDLER DRIVE, HANOVER PARK, IL 60133 USA
SN 1602-1622
EI 1757-9996
J9 ORAL HLTH PREV DENT
JI Oral Health Prev. Dent.
PY 2014
VL 12
IS 3
BP 265
EP 276
DI 10.3290/j.ohpd.a31666
PG 12
WC Dentistry, Oral Surgery & Medicine
SC Dentistry, Oral Surgery & Medicine
GA AR5LW
UT WOS:000343627100010
PM 24624392
ER
PT J
AU Levings, JL
Gunn, JP
AF Levings, Jessica Lee
Gunn, Janelle Peralez
TI From Menu to Mouth: Opportunities for Sodium Reduction in Restaurants
SO PREVENTING CHRONIC DISEASE
LA English
DT Article
ID FOODS
AB Restaurant foods can be a substantial source of sodium in the American diet. According to the Institute of Medicine, the significant contribution made by restaurants and food service menu items to Americans' sodium intake warrants targeted attention. Public health practitioners are uniquely poised to support sodium-reduction efforts in restaurants and help drive demand for lowersodium products through communication and collaboration with restaurant and food service professionals and through incentives for restaurants. This article discusses the role of the public health practitioner in restaurant sodium reduction and highlights select strategies that have been taken by state and local jurisdictions to support this effort.
C1 [Levings, Jessica Lee] Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, Chamblee, GA 30341 USA.
[Gunn, Janelle Peralez] Ctr Dis Control & Prevent, Atlanta, GA USA.
RP Levings, JL (reprint author), Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, MS K-72,4770 Buford Highway, Chamblee, GA 30341 USA.
EM JLevings@cdc.gov
NR 27
TC 0
Z9 0
U1 0
U2 0
PU CENTERS DISEASE CONTROL
PI ATLANTA
PA 1600 CLIFTON RD, ATLANTA, GA 30333 USA
SN 1545-1151
J9 PREV CHRONIC DIS
JI Prev. Chronic Dis.
PD JAN
PY 2014
VL 11
AR 130237
DI 10.5888/pcd11.130237
PG 5
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AR3XD
UT WOS:000343521600014
PM 24456646
ER
PT J
AU Murray, A
Ellis, MU
Castellanos, T
Gaul, Z
Sutton, MY
Sneed, CD
AF Murray, Ashley
Ellis, Monica U.
Castellanos, Ted
Gaul, Zaneta
Sutton, Madeline Y.
Sneed, Carl D.
TI Sexual health discussions between African-American mothers and mothers
of Latino descent and their children
SO SEX EDUCATION-SEXUALITY SOCIETY AND LEARNING
LA English
DT Article
DE mothers; young people; sexual health conversation; African-American;
Latino
ID RISK BEHAVIORS; ADOLESCENT COMMUNICATION; PARENT; FAMILIES; IMPACT;
PREGNANCY; PROGRAMS; YOUTH
AB We examined approaches used by African-American mothers and mothers of Latino descent for informal sex-related discussions with their children to inform sexually transmitted infection (STI)/HIV intervention development efforts. We recruited mothers (of children aged 12-15) from youth service agencies and a university in southern California. Fourteen focus groups were conducted: eight with African-American mothers (n = 31) and six with mothers of Latino descent (n = 24). Data were transcribed, coded for most common themes by four of the authors and reviewed for differences by gender of child. Four key themes emerged when focusing on parent-child discussions about sex: (1) sexual activity discussions took place for both sons and daughters; (2) protection from STI/HIV and pregnancy was a key topic; (3) the use of a direct, honest approach was preferred by mothers; and (4) seizing the moment was important for discussion opportunities. These data help broaden our understanding about the strategies used by African-American mothers and mothers of Latino descent for sexual health discussions with their sons and daughters. Evaluations of these for their potential impact on youth sexual health outcomes are warranted. The data can also contribute to the development of new culturally tailored parent-child communication strategies and HIV prevention interventions for young people of colour.
C1 [Murray, Ashley; Castellanos, Ted; Gaul, Zaneta; Sutton, Madeline Y.] Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA 30333 USA.
[Ellis, Monica U.] Fuller Grad Sch Psychol, Pasadena, CA USA.
[Ellis, Monica U.; Sneed, Carl D.] Calif State Univ Dominguez Hills, Dept Psychol, Carson, CA USA.
[Gaul, Zaneta] ICF Int, Atlanta, GA USA.
RP Murray, A (reprint author), Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA 30333 USA.
EM hfx8@cdc.gov
NR 39
TC 0
Z9 0
U1 1
U2 4
PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND
SN 1468-1811
EI 1472-0825
J9 SEX EDUC-SEX SOC LEA
JI Sex Educ.-Sex. Soc. Learn.
PY 2014
VL 14
IS 5
SI SI
BP 597
EP 608
DI 10.1080/14681811.2014.908767
PG 12
WC Education & Educational Research; Public, Environmental & Occupational
Health
SC Education & Educational Research; Public, Environmental & Occupational
Health
GA AR6SD
UT WOS:000343712200011
ER
PT J
AU Hojgaard, A
Lukacik, G
Piesman, J
AF Hojgaard, Andrias
Lukacik, Gary
Piesman, Joseph
TI Detection of Borrelia burgdorferi, Anaplasma phagocytophilum and Babesia
microti, with two different multiplex PCR assays (vol 5, pg 349, 2014)
SO TICKS AND TICK-BORNE DISEASES
LA English
DT Correction
C1 [Hojgaard, Andrias; Piesman, Joseph] Ctr Dis Control & Prevent, Natl Ctr Emerging & Zoonot Infect Dis, Div Vector Borne Infect Dis, Ft Collins, CO 80521 USA.
[Lukacik, Gary] New York State Dept Hlth, Bur Communicable Dis Control, Albany, NY USA.
RP Hojgaard, A (reprint author), Ctr Dis Control & Prevent, Div Vector Borne Infect Dis, 3156 Rampart Rd, Ft Collins, CO 80521 USA.
EM Fth3@cdc.gov
NR 1
TC 0
Z9 0
U1 0
U2 2
PU ELSEVIER GMBH, URBAN & FISCHER VERLAG
PI JENA
PA OFFICE JENA, P O BOX 100537, 07705 JENA, GERMANY
SN 1877-959X
EI 1877-9603
J9 TICKS TICK-BORNE DIS
JI Ticks Tick-Borne Dis.
PY 2014
VL 5
IS 6
BP 983
EP 983
DI 10.1016/j.ttbdis.2014.07.018
PG 1
WC Infectious Diseases; Microbiology; Parasitology
SC Infectious Diseases; Microbiology; Parasitology
GA AR2AG
UT WOS:000343385100058
ER
PT S
AU McKernan, JL
Ellenbecker, MJ
Holcroft, CA
Petersen, MR
AF McKernan, John L.
Ellenbecker, Michael J.
Holcroft, Christina A.
Petersen, Martin R.
GP ASHRAE
TI Development and Validation of Proposed Ventilation Equations for
Improved Exothermic Process Control
SO ASHRAE TRANSACTIONS 2014, VOL 120, PT 1
SE ASHRAE Transactions
LA English
DT Proceedings Paper
CT ASHRAE Winter Conference
CY 2014
CL New York, NY
SP ASHRAE
ID CONVECTION; HEAT
AB Exothermic or heated process contaminants have the potential to cause acute health effects such as heat stroke, and chronic effects such as manganese poisoning for an estimated 5-10 million American workers each year. Currently there are no specific occupational standards regarding exposure to heat from exothermic processes, therefore it is important to investigate techniques that can mitigate known and potential adverse occupational health effects. The research presented involved a review of the physical properties, heat transfer and meteorological theories governing buoyant air flow created by exothermic processes. These properties and theories were used to identify parameters and develop improved prediction equations required for the determination of buoyant volumetric flow used to design ventilation controls. Goals of this research were to develop and describe new (i.e. proposed) prediction equation, and compare them to currently accepted ones by Hemeon and the American Conference of Governmental Industrial Hygienists (ACGIH). Numerical assessments were conducted to compare solutions from the proposed equations for plume area, mean velocity and flow to those from the ACGIH and Hemeon. Parameters were varied for the dependent variables and solutions from the proposed, ACGIH, and Hemeon equations for plume area, mean velocity and flow were analyzed using a randomized complete block statistical design (ANOVA). Results indicate that the proposed plume mean velocity equation provides significantly greater means than either the ACGIH or Hemeon equations throughout the range of parameters investigated. The proposed equations for plume area and flow also provide significantly greater means than either the ACGIH or Hemeon equations at distances >1 m above exothermic processes. With an accurate solution for the total volumetric flow, ventilation engineers and practicing industrial hygienists are equipped with the necessary information to design and size hoods, as well as place them at an optimal distance from the source to provide adequate control of the rising plume. The equations developed will allow researchers and practitioners to determine the critical control parameters for exothermic processes, such as the exhaust flow necessary to improve efficacy and efficiency, while ensuring adequate worker protection.
C1 [McKernan, John L.] EPA Off Res & Dev, Engn Tech Support Ctr, Cincinnati, OH 45268 USA.
[Ellenbecker, Michael J.] U Massachusetts Lowell, Dept Work Environm, Lowell, MA USA.
[Holcroft, Christina A.] Tufts Univ, Grad Sch Biomed Sci, Boston, MA 02111 USA.
[Petersen, Martin R.] Ctr Dis Control & Prevent, Natl Inst Occupat Safety & Hlth, Cincinnati, OH 45226 USA.
RP McKernan, JL (reprint author), EPA Off Res & Dev, Engn Tech Support Ctr, Cincinnati, OH 45268 USA.
NR 26
TC 0
Z9 0
U1 1
U2 1
PU AMER SOC HEATING, REFRIGERATING AND AIR-CONDITIONING ENGS
PI ATLANTA
PA 1791 TULLIE CIRCLE NE, ATLANTA, GA 30329 USA
SN 0001-2505
J9 ASHRAE TRAN
PY 2014
VL 120
IS 1
PG 8
WC Thermodynamics; Construction & Building Technology
SC Thermodynamics; Construction & Building Technology
GA BB3GM
UT WOS:000342765800069
ER
PT J
AU Jeffries, WL
Okeke, JO
Gelaude, DJ
Torrone, EA
Gasiorowicz, M
Oster, AM
McCree, DH
Bertolli, J
AF Jeffries, William L.
Okeke, Janice O.
Gelaude, Deborah J.
Torrone, Elizabeth A.
Gasiorowicz, Mari
Oster, Alexandra M.
McCree, Donna Hubbard
Bertolli, Jeanne
TI An exploration of religion and spirituality among young, HIV-infected
gay and bisexual men in the USA
SO CULTURE HEALTH & SEXUALITY
LA English
DT Article
DE religion; spirituality; youth; gay and bisexual men; HIV; USA
ID AFRICAN-AMERICAN MEN; BLACK-MEN; UNITED-STATES; PREVENTION INTERVENTION;
DRUG-USE; SEX; HEALTH; RISK; HOMOPHOBIA; EXPERIENCES
AB Although religion and spirituality can promote healthy behaviours and mental well-being, negative religious experiences may harm sexual minority men's health. Despite increasing vulnerability to HIV infection among young gay and bisexual men, few studies examine how religion and spirituality might affect them. To this end, we interviewed young gay and bisexual men who were diagnosed with HIV infection during January 2006-June 2009. Questionnaires assessed religious service attendance, disclosure of sexuality within religious communities, and beliefs about homosexuality being sinful. A subset described religious and spiritual experiences in qualitative interviews. We calculated the prevalence of religion- and spirituality-related factors and identified themes within qualitative interviews. Among men completing questionnaires, 66% currently attended religious services, 16% believed they could disclose their sexuality at church, and 37% believed homosexuality was sinful. Participants who completed qualitative interviews commonly discussed religious attendance and negative experiences within religious settings. They often expressed their spirituality through prayer, and some used it to cope with adverse experiences. These data suggest that religion and spirituality are notable factors that shape young, HIV-infected gay and bisexual men's social contexts. Programmes and interventions that constructively engage with religious institutions and are sensitive to spiritual beliefs may promote these men's health. Aunque la religion y la espiritualidad pueden fomentar estilos de vida saludables y el bienestar mental, las experiencias religiosas negativas pueden danar la salud de los hombres que pertenecen a minorias sexuales. Pese a la creciente vulnerabilidad a la infeccion del virus del sida entre jovenes hombres gais y bisexuales, en pocos estudios se ha examinado como podria afectarles la religion y la espiritualidad. A este fin, llevamos a cabo entrevistas a jovenes hombres gais y bisexuales a los que se diagnostico una infeccion del VIH entre enero de 2006 y junio de 2009. En los cuestionarios se abordaron cuestiones como la asistencia a oficios religiosos, la revelacion de la sexualidad en las comunidades religiosas y la creencia de que la homosexualidad es un pecado. Un subgrupo describio sus experiencias religiosas y espirituales en entrevistas cualitativas. Calculamos la prevalencia de factores relacionados con la religion y la espiritualidad e identificamos temas en estas entrevistas cualitativas. Entre los hombres que completaron los cuestionarios, el 66% asistia actualmente a oficios religiosos, el 16% creia que podria revelar su sexualidad en la iglesia, y el 37% creia que la homosexualidad era un pecado. Los participantes que completaron las entrevistas cualitativas hablaron normalmente de su asistencia a servicios religiosos y experiencias negativas en entornos religiosos. Con frecuencia expresaron su espiritualidad por medio de la oracion, y algunos lo utilizaban para sobrellevar las experiencias adversas. Estos datos indican que la religion y la espiritualidad son factores notables que forman los contextos sociales de hombres jovenes, seropositivos, gais y bisexuales. Los programas y las intervenciones que permitan participar de una manera constructiva en instituciones religiosas y tengan en cuenta las creencias espirituales podrian fomentar la salud de estos hombres.
Bien que la religion et la spiritualite puissent favoriser les comportements propices a la bonne sante et au bien-etre mental, les experiences religieuses negatives peuvent nuire a la sante des hommes appartenant aux minorites sexuelles. Malgre une vulnerabilite croissante au VIH parmi les jeunes hommes gays et bisexuels, peu d'etudes ont examine comment la religion et la spiritualite peuvent les affecter. Dans cet objectif, nous avons interroge des jeunes hommes gays et bisexuels qui avaient recu un diagnostic d'infection a VIH entre janvier 2006 et juin 2009. Les questionnaires portaient sur l'assiduite aux services religieux, le devoilement de la sexualite dans les communautes religieuses et les croyances sur la nature coupable de l'homosexualite. Au cours d'entretiens qualitatifs, un sous-ensemble de participants a decrit les experiences religieuses et spirituelles. Nous avons calcule la prevalence des facteurs lies a la religion et a la spiritualite, et identifie des themes emergeant des entretiens qualitatifs. Parmi les hommes ayant rempli les questionnaires, 60 % se rendaient assidument aux services religieux ; 16 % etaient convaincus de pouvoir devoiler leur sexualite dans leur eglise; et 37 % pensaient que l'homosexualite etait coupable. Les participants aux entretiens qualitatifs ont discute, d'une maniere generale, de la pratique religieuse et des experiences negatives dans les environnements religieux. Ils exprimaient souvent leur spiritualite par la priere, et certains y avaient recours pour faire face aux experiences negatives. Ces donnees suggerent que la religion et la spiritualite sont des facteurs particuliers qui determinent les environnements sociaux des jeunes hommes gays et bisexuels infectes par le VIH. Les programmes et les interventions qui cooperent de maniere constructive avec des institutions religieuses et qui tiennent compte des croyances spirituelles pourraient favoriser la sante de ces hommes.
C1 [Jeffries, William L.; Gelaude, Deborah J.; Torrone, Elizabeth A.; Oster, Alexandra M.; McCree, Donna Hubbard; Bertolli, Jeanne] Ctr Dis Control & Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA 30333 USA.
Columbia Univ, Mailman Sch Publ Hlth, New York, NY USA.
[Gasiorowicz, Mari] Wisconsin Dept Hlth Serv, Div Publ Hlth, Madison, WI USA.
RP Jeffries, WL (reprint author), Ctr Dis Control & Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA 30333 USA.
EM wjeffries@cdc.gov
NR 45
TC 5
Z9 5
U1 4
U2 12
PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND
SN 1369-1058
EI 1464-5351
J9 CULT HEALTH SEX
JI Cult. Health Sex
PY 2014
VL 16
IS 9
BP 1070
EP 1083
DI 10.1080/13691058.2014.928370
PG 14
WC Family Studies; Social Sciences, Biomedical
SC Family Studies; Biomedical Social Sciences
GA AP6SU
UT WOS:000342208800005
PM 24992268
ER
PT S
AU Baloch, MA
AF Baloch, M. A.
BE Hoorfar, J
TI Leafy greens: the case study and real-life lessons from a
Shiga-toxin-producing Escherichia coli (STEC) O145 outbreak in romaine
lettuce
SO GLOBAL SAFETY OF FRESH PRODUCE: A HANDBOOK OF BEST PRACTICE, INNOVATIVE
COMMERCIAL SOLUTIONS AND CASE STUDIES
SE Woodhead Publishing Series in Food Science Technology and Nutrition
LA English
DT Article; Book Chapter
DE fresh produce-related outbreaks; E. coli O145; leafy greens; foodborne
illness outbreak; environmental assessment; systems approach; outbreak
investigation; environmental antecedents
ID FOOD
AB In April and May 2010, 33 cases of Escherichia coli O145 infections were reported from five US states. An epidemiologic investigation found that the illnesses were associated with the consumption of shredded lettuce. A traceback investigation from the processor led to a farm, Ranch A, that supplied lettuce to the processor. This chapter presents the findings of the field environmental assessment conducted in June 2010 on Ranch A and its surrounding watershed. The environmental assessment findings identify and enumerate environmental antecedents and contributing factors that might have influenced the contamination of the lettuce and the outbreak.
C1 US Ctr Dis Control & Prevent, Environm Hlth Serv Branch DEEHS NCEH, Atlanta, GA 30341 USA.
RP Baloch, MA (reprint author), US Ctr Dis Control & Prevent, Environm Hlth Serv Branch DEEHS NCEH, Atlanta, GA 30341 USA.
EM mbaloch@cdc.gov
OI Baloch, Mansoor/0000-0002-1502-086X
NR 20
TC 0
Z9 0
U1 0
U2 2
PU WOODHEAD PUBL LTD
PI CAMBRIDGE
PA ABINGTON HALL ABINGTON, CAMBRIDGE CB1 6AH, CAMBS, ENGLAND
SN 2042-8049
BN 978-1-78242-027-9; 978-1-78242-018-7
J9 WOODHEAD PUBL FOOD S
JI Woodhead Publ. Food Sci. Technol. Nutr.
PY 2014
IS 260
BP 340
EP 355
DI 10.1533/9781782420279.5.340
PG 16
WC Agronomy; Food Science & Technology
SC Agriculture; Food Science & Technology
GA BB2HQ
UT WOS:000341779200026
ER
PT J
AU Okall, DO
Ondenge, K
Nyambura, M
Otieno, FO
Hardnett, F
Turner, K
Mills, LA
Masinya, K
Chen, RT
Gust, DA
AF Okall, Dancun O.
Ondenge, Ken
Nyambura, Monicah
Otieno, Fredrick O.
Hardnett, Felicia
Turner, Kyle
Mills, Lisa A.
Masinya, Kennedy
Chen, Robert T.
Gust, Deborah A.
TI Men Who Have Sex With Men in Kisumu, Kenya: Comfort in Accessing Health
Services and Willingness to Participate in HIV Prevention Studies
SO JOURNAL OF HOMOSEXUALITY
LA English
DT Article
DE MSM; health services; participation in HIV research studies; stigma;
Africa; Kenya; confidentiality
ID VACCINE EFFICACY TRIAL; INFECTION; BOTSWANA; MSM
AB Men who have sex with men (MSM) are a crucial and marginalized at risk population for HIV in Africa but are poorly studied. Like other areas of Africa, homosexuality is illegal in Kenya. We assessed MSM comfort in accessing health services and willingness to participate in HIV prevention research in Kisumu, Kenya-an area of high HIV prevalence. We conducted a two-phase formative study with individual interviews (n = 15) and a structured survey (n = 51). Peer contact or snowball method (n = 43, 84.3%) was the primary recruitment strategy used to locate MSM. Exact logistic regression models were used for survey data analysis. Over 60% (32/51) of survey participants were not very comfortable seeking health services from a public hospital. Almost all MSM (49/51; 96.1%) reported willingness to be contacted to participate in future HIV research studies. Efforts to provide facilities that offer safe and confidential health services and health education for MSM is required. Continued community engagement with the MSM population in Kenya is needed to guide best practices for involving them in HIV prevention research.
C1 [Okall, Dancun O.; Ondenge, Ken; Nyambura, Monicah; Otieno, Fredrick O.] Kenya Govt Med Res Ctr, Kisumu, Kenya.
[Hardnett, Felicia; Chen, Robert T.; Gust, Deborah A.] Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA USA.
[Turner, Kyle] Inner City Fund Int, Atlanta, GA USA.
[Mills, Lisa A.] Ctr Dis Control & Prevent, Kenya Med Res Inst, Kisumu, Kenya.
[Masinya, Kennedy] Men AIDS Youth Grp, Kisumu, Kenya.
RP Gust, DA (reprint author), CDC, Div HIV AIDS Prevent, Epidemiol Branch, Clin Trials Team, 1600 Clifton Rd,Mail Stop E-45, Atlanta, GA 30333 USA.
EM dgust@cdc.gov
RI Amboko, Rashidi/D-9046-2015
FU Intramural CDC HHS [CC999999]
NR 24
TC 5
Z9 5
U1 0
U2 7
PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND
SN 0091-8369
EI 1540-3602
J9 J HOMOSEXUAL
JI J. Homosex.
PY 2014
VL 61
IS 12
BP 1712
EP 1726
DI 10.1080/00918369.2014.951261
PG 15
WC Psychology, Multidisciplinary; Social Sciences, Interdisciplinary
SC Psychology; Social Sciences - Other Topics
GA AP8IV
UT WOS:000342323600005
PM 25089554
ER
PT J
AU Fent, KW
Durgam, S
Mueller, C
AF Fent, Kenneth W.
Durgam, Srinivas
Mueller, Charles
TI Pharmaceutical Dust Exposure at Pharmacies Using Automatic Dispensing
Machines: A Preliminary Study
SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE
LA English
DT Article
DE pharmaceutical dust; active pharmaceutical ingredients; APIs; mail order
pharmacy; outpatient pharmacy; lactose; automatic dispensing machines;
robotic pill dispensers
ID OCCUPATIONAL-EXPOSURE; WORKERS; METHOTREXATE; INGREDIENTS; DUSTINESS;
INDUSTRY; POWDERS; LIMITS
AB Automatic dispensing machines (ADMs) used in pharmacies concentrate and dispense large volumes of pharmaceuticals, including uncoated tablets that can shed dust. We evaluated 43 employees' exposures to pharmaceutical dust at three pharmacies where ADMs were used. We used an optical particle counter to identify tasks that generated pharmaceutical dust. We collected 72 inhalable dust air samples in or near the employees' breathing zones. In addition to gravimetric analysis, our contract laboratory used internal methods involving liquid chromatography to analyze these samples for active pharmaceutical ingredients (APIs) and/or lactose, an inactive filler in tablets. We had to choose samples for these additional analyses because many methods used different extraction solvents. We selected 57 samples for analysis of lactose. We used real-time particle monitoring results, observations, and information from employees on the dustiness of pharmaceuticals to select 28 samples (including 13 samples that were analyzed for lactose) for analysis of specific APIs. Pharmaceutical dust was generated during a variety of tasks like emptying and refilling of ADM canisters. Using compressed air to clean canisters and manual count machines produced the overall highest peak number concentrations (19,000-580,000 particles/L) of smallest particles (count median aerodynamic diameter <= 2 mu m). Employees who refilled, cleaned, or repaired ADM canisters, or hand filled prescriptions were exposed to higher median air concentrations of lactose (5.0-12 mu g/m(3)) than employees who did other jobs (0.04-1.3 mu g/m(3)), such as administrative/office work, labeling/packaging, and verifying prescriptions. We detected 10 APIs in air, including lisinopril, a drug prescribed for high blood pressure, levothyroxine, a drug prescribed for hypothyroidism, and methotrexate, a hazardous drug prescribed for cancer and other disorders. Three air concentrations of lisinopril (1.8-2.7 mu g/m(3)) exceeded the lower bound of the manufacturer's hazard control band (1-10 mu g/m(3)). All other API air concentrations were below applicable occupational exposure limits. Our findings indicate that some pharmacy employees are exposed to multiple APIs and that measures are needed to control those exposures.
C1 [Fent, Kenneth W.; Mueller, Charles] NIOSH, Div Surveillance Hazard Evaluat & Field Studies, Cincinnati, OH 45226 USA.
[Durgam, Srinivas] Global Res Ctr, Niskayuna, NY USA.
RP Fent, KW (reprint author), NIOSH, Div Surveillance Hazard Evaluat & Field Studies, 1090 Tusculum Ave,MS R-14, Cincinnati, OH 45226 USA.
EM kfent@cdc.gov
NR 44
TC 0
Z9 0
U1 0
U2 6
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 530 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 1545-9624
EI 1545-9632
J9 J OCCUP ENVIRON HYG
JI J. Occup. Environ. Hyg.
PY 2014
VL 11
IS 11
BP 695
EP 705
DI 10.1080/15459624.2014.918983
PG 11
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA AP7UW
UT WOS:000342283700005
PM 24824046
ER
PT J
AU Boiano, JM
Steege, AL
Sweeney, MH
AF Boiano, James M.
Steege, Andrea L.
Sweeney, Marie H.
TI Adherence to Safe Handling Guidelines by Health Care Workers Who
Administer Antineoplastic Drugs
SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE
LA English
DT Article
DE antineoplastic drug administration; safe handling practices; health care
workers; hazardous drugs; chemotherapy; web-based survey
ID OCCUPATIONAL EXPOSURES; AWARENESS; NURSES; CHEMOTHERAPY; PERSONNEL;
SETTINGS; LEUKEMIA
AB The toxicity of antineoplastic drugs is well documented. Many are known or suspected human carcinogens where no safe exposure level exists. Authoritative guidelines developed by professional practice organizations and federal agencies for the safe handling of these hazardous drugs have been available for nearly three decades. As a means of evaluating the extent of use of primary prevention practices such as engineering, administrative and work practice controls, personal protective equipment (PPE), and barriers to using PPE, the National Institute for Safety and Health (NIOSH) conducted a web survey of health care workers in 2011. The study population primarily included members of professional practice organizations representing health care occupations which routinely use or come in contact with selected chemical agents. All respondents who indicated that they administered antineoplastic drugs in the past week were eligible to complete a hazard module addressing self-reported health and safety practices on this topic. Most (98%) of the 2069 respondents of this module were nurses. Working primarily in hospitals, outpatient care centers, and physician offices, respondents reported that they had collectively administered over 90 specific antineoplastic drugs in the past week, with carboplatin, cyclophosphamide, and paclitaxel the most common. Examples of activities which increase exposure risk, expressed as percent of respondents, included: failure to wear nonabsorbent gown with closed front and tight cuffs (42%); intravenous (I. V.) tubing primed with antineoplastic drug by respondent (6%) or by pharmacy (12%); potentially contaminated clothing taken home (12%); spill or leak of antineoplastic drug during administration (12%); failure to wear chemotherapy gloves (12%); and lack of hazard awareness training (4%). The most common reason for not wearing gloves or gowns was "skin exposure was minimal"; 4% of respondents, however, reported skin contact during handling and administration. Despite the longstanding availability of safe handling guidance, recommended practices are not always followed, underscoring the importance of training and education for employers and workers.
C1 [Boiano, James M.; Steege, Andrea L.; Sweeney, Marie H.] NIOSH, Div Surveillance Hazard Evaluat & Field Studies, Cincinnati, OH 45226 USA.
RP Boiano, JM (reprint author), NIOSH, Div Surveillance Hazard Evaluat & Field Studies, 1090 Tusculum Ave,MSR-17, Cincinnati, OH 45226 USA.
EM jboiano@cdc.gov
RI Steege, Andrea/H-8900-2016
OI Steege, Andrea/0000-0001-5665-2559
FU National Institute for Occupational Safety and Health
FX The authors thank Westat, Inc., for their collaboration in developing,
testing, and conducting the survey. The authors are grateful to the
professional practice organizations and members who participated in the
survey. We also thank Seth Eisenberg, Gayle DeBord, and Tom Connor for
their valuable comments on and suggestions for an early draft of the
manuscript. This project was supported by the National Institute for
Occupational Safety and Health.
NR 33
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Z9 12
U1 3
U2 21
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 530 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 1545-9624
EI 1545-9632
J9 J OCCUP ENVIRON HYG
JI J. Occup. Environ. Hyg.
PY 2014
VL 11
IS 11
BP 728
EP 740
DI 10.1080/15459624.2014.916809
PG 13
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA AP7UW
UT WOS:000342283700009
PM 24766408
ER
PT J
AU Breuer, D
Ashley, K
AF Breuer, Dietmar
Ashley, Kevin
TI New NIOSH Methods for Sampling and Analysis of Airborne Inorganic Acids
SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE
LA English
DT Article
ID MEASURING EXPOSURE; PERFORMANCE
AB Newly published NIOSH methods for inorganic acids, that are technically harmonized with relevant parallel ISO standard, have been promulgated. These methods have been extensively validated and represent significant improvements in sampling and analytical methodologies for inorganic mists and vapors in workplace atmospheres. The equivalent constructs ofmethod accuracy, as defined by theNIOSH Accuracy Criterion,((20)) and expanded uncertainty, as elucidated in EN 482((11)) and ASTM D7440((21)) (which apply the ISO/IEC Guide to the expression of uncertainty in measurement (GUM)((22)) to air quality measurements), have been previously explained by Bartley.((23)) Under these considerations is intended that, in the near future, additional occupational exposure monitoring methods based on international voluntary consensus standards will be incorporated into the NIOSH Manual of Analytical Methods.
C1 [Breuer, Dietmar] IFA Inst Occupat Safety & Hlth German Social Acci, Inst Arbeitsschutz Deutsch Gesetzlichen Unfallver, D-53757 St Augustin, Germany.
[Ashley, Kevin] NIOSH, US Dept HHS, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA.
RP Breuer, D (reprint author), IFA Inst Occupat Safety & Hlth German Social Acci, Inst Arbeitsschutz Deutsch Gesetzlichen Unfallver, D-53757 St Augustin, Germany.
EM dietmar.breuer@dguv.de
FU IFA; NIOSH
FX This work was carried out under the auspices of a formal Memorandum of
Understanding (MOU) between IFA and NIOSH.
NR 23
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U1 0
U2 1
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 530 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 1545-9624
EI 1545-9632
J9 J OCCUP ENVIRON HYG
JI J. Occup. Environ. Hyg.
PY 2014
VL 11
IS 11
BP D208
EP D211
DI 10.1080/15459624.2014.955183
PG 4
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA AP7UW
UT WOS:000342283700004
PM 25153625
ER
PT J
AU Garcia, A
Jones, E
Echt, AS
Hall, RM
AF Garcia, Alberto
Jones, Erica
Echt, Alan S.
Hall, Ronald M.
TI An Evaluation of an Aftermarket Local Exhaust Ventilation Device for
Suppressing Respirable Dust and Respirable Crystalline Silica Dust from
Powered Saws
SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE
LA English
DT Article
AB The objective of this study was to quantify the respirable dust and respirable silica exposures of roofing workers using an electric-powered circular saw with an aftermarket local exhaust ventilation attachment to cut concrete roofing tiles. The study was conducted to determine whether the local exhaust ventilation attachment was able to control respirable dust and respirable silica exposure below occupational exposure limits (OELs). Time-integrated filter samples and direct reading respirable dust concentrations were evaluated. The local exhaust ventilation consisted of a shroud attached to the cutting plane of the saw; the shroud was then connected to a small electric axial fan, which is intended to collect dust at the point of generation. All sampling was conducted with the control in use.
Roofers are defined as those individuals who only lay tiles. Cutters/roofers are defined as those workers who operate the powered saw to cut tiles and also lay tiles. Respirable dust from this evaluation ranged from 0.13 to 6.59 milligrams per cubic meter (mg/m(3)) with a geometric mean of 0.38 mg/m(3) for roofers and from 0.45 to 3.82 mg/m(3) with a geometric mean of 1.84 mg/m(3) for cutters/roofers. Cutters/roofers usually handle areas close to crevices, edges, or tips of the roof whereas roofers handle areas where complete tiles can be placed. The respirable dust exposures for all cutters/roofers indicated concentrations exceeding the Occupational Safety and Health Administration's (OSHA) permissible exposure limit (PEL) for respirable dust containing silica; it was also exceeded for some of the roofers. The respirable silica concentrations ranged from 0.04 to 0.15 mg/m(3) with a geometric mean of 0.09 mg/m(3) for roofers, and from 0.13 to 1.21 mg/m(3) with a geometric mean of 0.48 mg/m(3) for cutters/roofers. As with respirable dust, the respirable silica exposures for cutters/roofers were higher than the exposures for roofers.
C1 [Garcia, Alberto; Jones, Erica; Echt, Alan S.; Hall, Ronald M.] NIOSH, DART, Cincinnati, OH 45226 USA.
RP Garcia, A (reprint author), NIOSH, 4676 Columbia Pkwy,R5, Cincinnati, OH 45226 USA.
EM agarcia1@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 11
TC 0
Z9 0
U1 1
U2 1
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 530 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 1545-9624
EI 1545-9632
J9 J OCCUP ENVIRON HYG
JI J. Occup. Environ. Hyg.
PY 2014
VL 11
IS 11
BP D200
EP D207
DI 10.1080/15459624.2014.955182
PG 8
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA AP7UW
UT WOS:000342283700003
PM 25148513
ER
PT J
AU Cunningham, TJ
Ford, ES
Croft, JB
Merrick, MT
Rolle, IV
Giles, WH
AF Cunningham, Timothy J.
Ford, Earl S.
Croft, Janet B.
Merrick, Melissa T.
Rolle, Italia V.
Giles, Wayne H.
TI Sex-specific relationships between adverse childhood experiences and
chronic obstructive pulmonary disease in five states
SO INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
LA English
DT Article
DE chronic obstructive pulmonary disease; childhood; abuse; sex
ID UNITED-STATES; FEMALE SMOKERS; SMOKING; ADULTS; RISK; SURVEILLANCE;
DYSFUNCTION; FRAMEWORK; ABUSE; COPD
AB Purpose: Adverse childhood experiences (ACEs) before age 18 have been repeatedly associated with several chronic diseases in adulthood such as depression, heart disease, cancer, diabetes, and stroke. We examined sex-specific relationships between individual ACEs and the number of ACEs with chronic obstructive pulmonary disease (COPD) in the general population.
Materials and methods: Data from 26,546 women and 19,015 men aged >= 18 years in five states of the 2011 Behavioral Risk Factor Surveillance System were analyzed. We used log-linear regression to estimate prevalence ratios (PRs) and their corresponding 95% confidence intervals (CIs) for the relationship of eight ACEs with COPD after adjustment for age group, race/ethnicity, marital status, educational attainment, employment, asthma history, health insurance coverage, and smoking status.
Results: Some 63.8% of women and 62.2% of men reported >= 1 ACE. COPD was reported by 4.9% of women and 4.0% of men. In women, but not in men, there was a higher likelihood of COPD associated with verbal abuse (PR = 1.30, 95% CI: 1.05, 1.61), sexual abuse (PR = 1.69, 95% CI: 1.36, 2.10), living with a substance abusing household member (PR = 1.49, 95% CI: 1.23, 1.81), witnessing domestic violence (PR = 1.40, 95% CI: 1.14, 1.72), and parental separation/divorce (PR = 1.47, 95% CI: 1.21, 1.80) during childhood compared to those with no individual ACEs. Reporting >= 5 ACEs (PR = 2.08, 95% CI: 1.55, 2.80) compared to none was associated with a higher likelihood of COPD among women only.
Conclusion: ACEs are related to COPD, especially among women. These findings underscore the need for further research that examines sex-specific differences and the possible mechanisms linking ACEs and COPD. This work adds to a growing body of research suggesting that ACEs may contribute to health problems later in life and suggesting a need for program and policy solutions.
C1 [Cunningham, Timothy J.; Ford, Earl S.; Croft, Janet B.; Giles, Wayne H.] Ctr Dis Control & Prevent, Div Populat Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30341 USA.
[Merrick, Melissa T.] Ctr Dis Control & Prevent, Div Violence Prevent, Natl Ctr Injury Prevent & Control, Atlanta, GA 30341 USA.
[Rolle, Italia V.] Ctr Dis Control & Prevent, Off Smoking & Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30341 USA.
RP Cunningham, TJ (reprint author), Ctr Dis Control & Prevent, 4770 Buford Highway,Mailstop F78, Atlanta, GA 30341 USA.
EM tjcunningham@cdc.gov
NR 30
TC 8
Z9 9
U1 0
U2 5
PU DOVE MEDICAL PRESS LTD
PI ALBANY
PA PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND
SN 1178-2005
J9 INT J CHRONIC OBSTR
JI Int. J. Chronic Obstr. Pulm. Dis.
PY 2014
VL 9
BP 1033
EP 1042
DI 10.2147/COPD.S68226
PG 10
WC Respiratory System
SC Respiratory System
GA AP6PK
UT WOS:000342199500001
PM 25298732
ER
PT J
AU Kraft, JM
Wilkins, KG
Morales, GJ
Widyono, M
Middlestadt, SE
AF Kraft, Joan Marie
Wilkins, Karin Gwinn
Morales, Guiliana J.
Widyono, Monique
Middlestadt, Susan E.
TI An Evidence Review of Gender-Integrated Interventions in Reproductive
and Maternal-Child Health
SO JOURNAL OF HEALTH COMMUNICATION
LA English
DT Review
ID INTIMATE PARTNER VIOLENCE; CONTRACEPTION; PROJECT; IMPACT; TRIAL; INDIA;
MEN; ASSOCIATION; PREGNANCY; ETHIOPIA
AB Evidence-based behavior change interventions addressing gender dynamics must be identified and disseminated to improve child health outcomes. Interventions were identified from systematic searches of the published literature and a web-based search (Google and implementer's websites). Studies were eligible if an intervention addressed gender dynamics (i.e., norms, unequal access to resources), measured relevant behavioral outcomes (e.g., family planning, antenatal care, nutrition), used at least a moderate evaluation design, and were implemented in low- or middle-income countries. Of the 23 interventions identified, 22 addressed reproductive and maternal-child health behaviors (e.g., birth spacing, antenatal care, breastfeeding) that improve child health. Eight interventions were accommodating (i.e., acknowledged, but did not seek to change gender dynamics), and 15 were transformative (i.e., sought to change gender dynamics). The majority of evaluations (n=12), including interventions that engaged men and women to modify gender norms, had mixed effects. Evidence was most compelling for empowerment approaches (i.e., participatory action for maternal-child health; increase educational and economic resources, and modify norms to reduce child marriage). Two empowerment approaches had sufficient evidence to warrant scaling-up. Research is needed to assess promising approaches, particularly those that engage men and women to modify gender norms around communication and decision making between spouses.
C1 [Kraft, Joan Marie] Ctr Dis Control & Prevent, Atlanta, GA 30341 USA.
[Wilkins, Karin Gwinn] Univ Texas Austin, Austin, TX 78712 USA.
[Morales, Guiliana J.] Univ N Carolina, Gillings Sch Global Publ Hlth, Dept Hlth Behav, Chapel Hill, NC USA.
[Widyono, Monique] US Agcy Int Dev, Bur Global Hlth, Washington, DC 20523 USA.
[Middlestadt, Susan E.] Indiana Univ Sch Publ Hlth, Bloomington, IN USA.
RP Kraft, JM (reprint author), Ctr Dis Control & Prevent, DRH, 4770 Buford Highway NE,MS F74, Atlanta, GA 30341 USA.
EM jik4@cdc.gov
NR 57
TC 16
Z9 16
U1 4
U2 18
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 530 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 1081-0730
EI 1087-0415
J9 J HEALTH COMMUN
JI J. Health Commun.
PY 2014
VL 19
SU 1
SI SI
BP 122
EP 141
DI 10.1080/10810730.2014.918216
PG 20
WC Communication; Information Science & Library Science
SC Communication; Information Science & Library Science
GA AP4QC
UT WOS:000342062000007
PM 25207450
ER
PT J
AU Frieden, TR
AF Frieden, Thomas R.
TI Six Components Necessary for Effective Public Health Program
Implementation
SO AMERICAN JOURNAL OF PUBLIC HEALTH
LA English
DT Article
ID NEW-YORK-CITY; BLOOD-STREAM INFECTIONS; TUBERCULOSIS-CONTROL;
UNITED-STATES; SMOKING; WORLDWIDE; AIR
AB Public health programs succeed and survive if organizations and coalitions address 6 key areas.
(1) Innovation to develop the evidence base for action; (2) a technical package of a limited number of high-priority, evidence-based interventions that together will have a major impact; (3) effective performance management, especially through rigorous, real-time monitoring, evaluation, and program improvement; (4) partnerships and coalitions with public-and private-sector organizations; (5) communication of accurate and timely information to the health care community, decision makers, and the public to effect behavior change and engage civil society; and (6) political commitment to obtain resources and support for effective action.
Programs including smallpox eradication, tuberculosis control, tobacco control, polio eradication, and others have made progress by addressing these 6 areas.
C1 Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
RP Frieden, TR (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd NE,MS D-14, Atlanta, GA 30333 USA.
EM tfrieden@cdc.gov
NR 46
TC 34
Z9 34
U1 3
U2 15
PU AMER PUBLIC HEALTH ASSOC INC
PI WASHINGTON
PA 800 I STREET, NW, WASHINGTON, DC 20001-3710 USA
SN 0090-0036
EI 1541-0048
J9 AM J PUBLIC HEALTH
JI Am. J. Public Health
PD JAN
PY 2014
VL 104
IS 1
BP 17
EP 22
DI 10.2105/AJPH.2013.301608
PG 6
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AO9TW
UT WOS:000341701400024
PM 24228653
ER
PT J
AU Laney, AS
Attfield, MD
AF Laney, A. Scott
Attfield, Michael D.
TI Examination of Potential Sources of Bias in the US Coal Workers' Health
Surveillance Program
SO AMERICAN JOURNAL OF PUBLIC HEALTH
LA English
DT Article
ID PROGRESSIVE MASSIVE FIBROSIS; UNITED-STATES; PNEUMOCONIOSIS; MINERS;
PREVALENCE; EXPOSURE
AB Objectives. We examined the potential influences of certain selection factors on the utility of the Coal Workers' Health Surveillance Program (CWHSP) data for tracking disease distribution and trends.
Methods. We combined data from the CWHSP and the Energy Information Administration to examine any influence of variable worker participation on observed disease prevalence. We evaluated effects of differential participation by coal mining region, temporal changes in employment, and active surveillance efforts.
Results. The published findings of pneumoconiosis distribution and trends from the CWHSP were robust compared with the various participation factors that might have affected their validity for population-based estimates of disease burden. Exploration of factors that could potentially bias the findings generally led to small increases in the primary estimates, mostly for the early years of the program.
Conclusions. We confirmed previously reported findings that there was a high prevalence of coal worker pneumoconiosis (CWP) around 1970-1974, a substantial decline in 1995-1999, and indications of an increase since then. Overall our findings suggest that the previously reported distribution and trends in CWP prevalence were broadly accurate.
C1 [Laney, A. Scott; Attfield, Michael D.] NIOSH, Surveillance Branch, Div Resp Dis Studies, Ctr Dis Control & Prevent, Morgantown, WV 26505 USA.
RP Laney, AS (reprint author), NIOSH, Surveillance Branch, Div Resp Dis Studies, Ctr Dis Control & Prevent, 1095 Willowdale Rd,Mail Stop HG900-2, Morgantown, WV 26505 USA.
EM alaney@cdc.gov
NR 33
TC 6
Z9 6
U1 1
U2 2
PU AMER PUBLIC HEALTH ASSOC INC
PI WASHINGTON
PA 800 I STREET, NW, WASHINGTON, DC 20001-3710 USA
SN 0090-0036
EI 1541-0048
J9 AM J PUBLIC HEALTH
JI Am. J. Public Health
PD JAN
PY 2014
VL 104
IS 1
BP 165
EP 170
DI 10.2105/AJPH.2012.301051
PG 6
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AO9TW
UT WOS:000341701400044
PM 23678894
ER
PT J
AU Dombkowski, KJ
Cowan, AE
Potter, RC
Dong, SM
Kolasa, M
Clark, SJ
AF Dombkowski, Kevin J.
Cowan, Anne E.
Potter, Rachel C.
Dong, Shiming
Kolasa, Maureen
Clark, Sarah J.
TI Statewide Pandemic Influenza Vaccination Reminders for Children with
Chronic Conditions
SO AMERICAN JOURNAL OF PUBLIC HEALTH
LA English
DT Article
ID IMMUNIZATION INFORMATION-SYSTEMS; APRIL-AUGUST 2009; UNITED-STATES;
IDENTIFY CHILDREN; 2009-JANUARY 2010; ASTHMA; RECALL; NOTIFICATIONS;
TECHNOLOGIES; EXPERIENCES
AB Objectives. We evaluated the use of a statewide immunization information system (IIS) to target influenza vaccine reminders to high-risk children during a pandemic.
Methods. We used Michigan's IIS to identify high-risk children (i.e., those with 1 chronic condition) aged 6 months to 18 years with no record of pH1N1 vaccination among children currently or previously enrolled in Medicaid (n = 202 133). Reminders were mailed on December 7, 2009. We retrospectively assessed children's eligibility for evaluation and compared influenza vaccination rates across 3 groups on the basis of their high-risk and reminder status.
Results. Of the children sent reminders, 53 516 were ineligible. Of the remaining 148 617 children, vaccination rates were higher among the 142 383 high-risk children receiving reminders than among the 6234 high-risk children with undeliverable reminders and the 142 383 control group children without chronic conditions who were not sent reminders.
Conclusions. Midseason reminders to parents of unvaccinated high-risk children with current or past Medicaid enrollment were associated with increased pH1N1 and seasonal influenza vaccination rates. Future initiatives should consider strategies to expand targeting of high-risk groups and improve IIS reporting during pandemic events.
C1 [Dombkowski, Kevin J.; Cowan, Anne E.; Dong, Shiming; Clark, Sarah J.] Univ Michigan, Div Gen Pediat, Child Hlth Evaluat & Res Unit, Ann Arbor, MI 48109 USA.
[Potter, Rachel C.] Michigan Dept Community Hlth, Lansing, MI USA.
[Kolasa, Maureen] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Atlanta, GA USA.
RP Dombkowski, KJ (reprint author), Univ Michigan, Div Gen Pediat, 300 North Ingalls,Room 6D05, Ann Arbor, MI 48109 USA.
EM kjd@med.umich.edu
FU Centers for Disease Control and Prevention through Association of
Prevention Teaching and Research
FX This work was funded by the Centers for Disease Control and Prevention
through a cooperative agreement with the Association of Prevention
Teaching and Research.
NR 32
TC 2
Z9 2
U1 0
U2 1
PU AMER PUBLIC HEALTH ASSOC INC
PI WASHINGTON
PA 800 I STREET, NW, WASHINGTON, DC 20001-3710 USA
SN 0090-0036
EI 1541-0048
J9 AM J PUBLIC HEALTH
JI Am. J. Public Health
PD JAN
PY 2014
VL 104
IS 1
BP E39
EP E44
DI 10.2105/AJPH.2013.301662
PG 6
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AO9TW
UT WOS:000341701400010
PM 24228668
ER
PT J
AU Kansagra, SM
Papadouka, V
Geevarughese, A
Hansen, MA
Konty, KJ
Zucker, JR
AF Kansagra, Susan M.
Papadouka, Vikki
Geevarughese, Anita
Hansen, Michael A.
Konty, Kevin J.
Zucker, Jane R.
TI Reaching Children Never Previously Vaccinated for Influenza Through a
School-Located Vaccination Program
SO AMERICAN JOURNAL OF PUBLIC HEALTH
LA English
DT Article
ID IMMUNIZATION; UNIVERSAL; CITY
AB Objectives. We determined the success of the school-located vaccination (SLV) program, implemented in 2009 in New York City to deliver pandemic influenza A (H1N1) monovalent vaccine (pH1N1), versus provider offices in reaching children who had never previously received influenza vaccine.
Methods. We compared the immunization history of children vaccinated in school versus provider offices. We included records in the Citywide Immunization Registry with pH1N1 administered between October 2009 and March 2010 to elementary school-aged children.
Results. In total, 96 524 children received pH1N1 vaccine in schools, and 102 933 children received pH1N1 vaccine in provider offices. Of children vaccinated in schools, 34% had never received seasonal influenza vaccination in the past, compared with only 10% of children vaccinated at provider offices (P < .001). Children vaccinated in schools were more likely to have received a second dose of pH1N1 in 2009-2010 than those vaccinated in provider offices (80% vs 45%).
Conclusions. The SLV program was more successful at reaching children who had never received influenza immunization in the past and should be considered as a strategy for delivering influenza vaccine in routine and emergency situations.
C1 [Kansagra, Susan M.; Papadouka, Vikki; Geevarughese, Anita; Hansen, Michael A.; Konty, Kevin J.] New York City Dept Hlth & Mental Hyg, New York, NY USA.
[Zucker, Jane R.] Ctr Dis Control & Prevent, Immunizat Serv Div, Natl Ctr Immunizat & Resp Dis, New York, NY USA.
[Zucker, Jane R.] New York City Dept Hlth & Mental Hyg, Bur Immunizat, New York, NY USA.
RP Kansagra, SM (reprint author), New York City Dept Hlth & Mental Hyg, 42-09 28th St,9th Floor, Queens, NY 11101 USA.
EM skansagr@health.nyc.gov
FU Public Health Emergency Preparedness Cooperative Agreement
[5U90TP221298-08]; Public Health Emergency Response Grant from the
Centers for Disease Control and Prevention (CDC)
[CDC-RFA-TP09-902-H1N109]
FX All phases of this study were supported by the Public Health Emergency
Preparedness Cooperative Agreement (grant no. 5U90TP221298-08) and the
Public Health Emergency Response Grant (funding opportunity no.
CDC-RFA-TP09-902-H1N109) from the Centers for Disease Control and
Prevention (CDC).
NR 20
TC 3
Z9 3
U1 0
U2 0
PU AMER PUBLIC HEALTH ASSOC INC
PI WASHINGTON
PA 800 I STREET, NW, WASHINGTON, DC 20001-3710 USA
SN 0090-0036
EI 1541-0048
J9 AM J PUBLIC HEALTH
JI Am. J. Public Health
PD JAN
PY 2014
VL 104
IS 1
BP E45
EP E49
DI 10.2105/AJPH.2013.301671
PG 5
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AO9TW
UT WOS:000341701400011
PM 24228652
ER
PT J
AU Kattan, JA
Kudish, KS
Cadwell, BL
Soto, K
Hadler, JL
AF Kattan, Jessica A.
Kudish, Kathy S.
Cadwell, Betsy L.
Soto, Kristen
Hadler, James L.
TI Effect of Vaccination Coordinators on Socioeconomic Disparities in
Immunization Among the 2006 Connecticut Birth Cohort
SO AMERICAN JOURNAL OF PUBLIC HEALTH
LA English
DT Article
ID UNITED-STATES; RISK-FACTORS; US CHILDREN; COVERAGE; CARE; DELAY
AB Objectives. We examined socioeconomic status (SES) disparities and the influence of state Immunization Action Plan-funded vaccination coordinators located in low-SES areas of Connecticut on childhood vaccination up-to-date (UTD) status at age 24 months.
Methods. We examined predictors of underimmunization among the 2006 birth cohort (n = 34568) in the state's Immunization Information System, including individual demographic and SES data, census tract SES data, and residence in an area with a vaccination coordinator. We conducted multilevel logistic regression analyses.
Results. Overall, 81% of children were UTD. Differences by race/ethnicity and census tract SES were typically under 5%. Not being UTD at age 7 months was the strongest predictor of underimmunization at age 24 months. Among children who were not UTD at age 7 months, only Medicaid enrollment (adjusted odds ratio [AOR] = 0.6; 95% confidence interval [CI] = 0.5, 0.7) and residence in an area with a vaccination coordinator (AOR = 0.7; 95% CI = 0.6, 0.9) significantly decreased the odds of subsequent underimmunization.
Conclusions. SES disparities associated with underimmunization at age 24 months were limited. Efforts focused on vaccinating infants born in low SES circumstances can minimize disparities.
C1 [Kattan, Jessica A.] Ctr Dis Control & Prevent, Hartford, CT USA.
[Kattan, Jessica A.] Connecticut Dept Publ Hlth, Infect Dis Sect, Hartford, CT USA.
[Kudish, Kathy S.] Connecticut Dept Publ Health, Immunizat Program, Hartford, CT USA.
[Kudish, Kathy S.] Connecticut Dept Publ Health, Infect Dis Sect, Hartford, CT USA.
[Cadwell, Betsy L.] CDC, Off Surveillance Epidemiol & Lab Serv, Atlanta, GA 30333 USA.
[Hadler, James L.] Connecticut Emerging Infect Program, New Haven, CT USA.
RP Kattan, JA (reprint author), New York City Dept Hlth & Mental Hyg, Bur Alcohol & Drug Use Prevent Care & Treatment, Gotham Ctr, 42-09 28th St,19th Floor,CN 14, Queens, NY 11101 USA.
EM jkattan@health.nyc.gov
NR 24
TC 3
Z9 3
U1 3
U2 4
PU AMER PUBLIC HEALTH ASSOC INC
PI WASHINGTON
PA 800 I STREET, NW, WASHINGTON, DC 20001-3710 USA
SN 0090-0036
EI 1541-0048
J9 AM J PUBLIC HEALTH
JI Am. J. Public Health
PD JAN
PY 2014
VL 104
IS 1
BP E74
EP E81
DI 10.2105/AJPH.2013.301418
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AO9TW
UT WOS:000341701400015
PM 24228642
ER
PT J
AU Shen, XX
An, YL
Zhang, P
Wang, JP
Gregg, EW
Zhang, B
Li, H
Gong, QH
Chen, YY
Xing, XY
Engelgau, M
Hu, YH
Bennett, PH
Li, GW
AF Shen, Xiaoxia
An, Yali
Zhang, Ping
Wang, Jinping
Gregg, Edward W.
Zhang, Bo
Li, Hui
Gong, Qiuhong
Chen, Yanyan
Xing, Xiaoyan
Engelgau, Michael
Hu, Yinghua
Bennett, Peter H.
Li, Guangwei
TI Both Fasting and 2-hour post load glycemic progression predicts
subsequent cardiovascular events in persons with impaired glucose
tolerance: 23-year follow-up of the Da Qing diabetes prevention study
SO CARDIOLOGY
LA English
DT Meeting Abstract
C1 [Shen, Xiaoxia; An, Yali; Gong, Qiuhong; Chen, Yanyan; Li, Guangwei] Fuwai Hosp, Ctr Endocrinol & Cardiovasc Dis, Beijing, Peoples R China.
[Zhang, Ping; Gregg, Edward W.; Engelgau, Michael] CDC, Div Diabet Translat, Atlanta, GA 30333 USA.
[Wang, Jinping; Li, Hui; Hu, Yinghua] Da Qing First Hosp, Dept Cardiol, Da Qing, Peoples R China.
[Bennett, Peter H.] NIDDK, Phoenix Epidemiol & Clin Res Branch, Phoenix, AZ USA.
[Zhang, Bo; Xing, Xiaoyan; Li, Guangwei] China Japan Friendship Hosp, Dept Endocrinol, Beijing, Peoples R China.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU KARGER
PI BASEL
PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND
SN 0008-6312
EI 1421-9751
J9 CARDIOLOGY
JI Cardiology
PY 2014
VL 129
SU 1
BP 11
EP 11
PG 1
WC Cardiac & Cardiovascular Systems
SC Cardiovascular System & Cardiology
GA AO2PY
UT WOS:000341168900030
ER
PT J
AU Hirst, DVL
Dunn, KH
Shulman, SA
Hammond, DR
Sestito, N
AF Hirst, Deborah V. L.
Dunn, Kevin H.
Shulman, Stanley A.
Hammond, Duane R.
Sestito, Nicholas
TI Evaluation of Engineering Controls for the Mixing Of Flavorings
Containing Diacetyl and other Volatile Ingredients
SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE
LA English
DT Article
DE mixing workers; exhaust hood; diacetyl; tracer gas testing; emission
control; mixing tank
ID MICROWAVE-POPCORN PLANT; LUNG-DISEASE RISK; BRONCHIOLITIS OBLITERANS;
MANUFACTURING-INDUSTRY; WORKERS; EXPOSURES
AB Exposures to diacetyl, a primary ingredient of butter flavoring, have been shown to cause respiratory disease among workers who mix flavorings. This study focused on evaluating ventilation controls designed to reduce emissions from the flavor mixing tanks, the major source of diacetyl in the plants. Five exhaust hood configurations were evaluated in the laboratory: standard hinged lid-opened, standard hinged lid-closed, hinged lid-slotted, dome with 38-mm gap, and dome with 114-mm gap. Tracer gas tests were performed to evaluate quantitative capture efficiency for each hood. A perforated copper coil was used to simulate an area source within the 1.2-meter diameter mixing tank. Capture efficiencies were measured at four hood exhaust flow rates (2.83, 5.66, 11.3, and 17.0 cubic meters per min) and three cross draft velocities (0, 30, and 60 meters per min). All hoods evaluated performed well with capture efficiencies above 90% for most combinations of exhaust volume and cross drafts. The standard hinged lid was the least expensive to manufacture and had the best average capture efficiency (over 99%) in the closed configuration for all exhaust flow rates and cross drafts. The hinged lid-slotted hood had some of the lowest capture efficiencies at the low exhaust flow rates compared to the other hood designs. The standard hinged lid performed well, even in the open position, and it provided a flexible approach to controlling emissions from mixing tanks. The dome hood gave results comparable to the standard hinged lid but it is more expensive to manufacture. The results of the study indicate that emissions from mixing tanks used in the production of flavorings can be controlled using simple inexpensive exhaust hoods.
C1 [Hirst, Deborah V. L.; Dunn, Kevin H.; Shulman, Stanley A.; Hammond, Duane R.; Sestito, Nicholas] NIOSH, Div Appl Res & Technol, Cincinnati, OH 45226 USA.
RP Hirst, DVL (reprint author), 1090 Tusculum Ave MS R-5, Cincinnati, OH 45226 USA.
EM DHirst@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 13
TC 2
Z9 2
U1 1
U2 4
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 530 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 1545-9624
EI 1545-9632
J9 J OCCUP ENVIRON HYG
JI J. Occup. Environ. Hyg.
PY 2014
VL 11
IS 10
BP 680
EP 687
DI 10.1080/15459624.2014.904517
PG 8
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA AO0LX
UT WOS:000341001900010
PM 24649880
ER
PT J
AU Dunn, KH
Tsai, CSJ
Woskie, SR
Bennett, JS
Garcia, A
Ellenbecker, MJ
AF Dunn, Kevin H.
Tsai, Candace Su-Jung
Woskie, Susan R.
Bennett, James S.
Garcia, Alberto
Ellenbecker, Michael J.
TI Evaluation of Leakage From Fume Hoods Using Tracer Gas, Tracer
Nanoparticles and Nanopowder Handling Test Methodologies
SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE
LA English
DT Article
ID WALLED-CARBON-NANOTUBES; CENTRAL-NERVOUS-SYSTEM; TIO2 NANOPARTICLES;
PERFORMANCE; MICE; TRANSLOCATION; EXPOSURES; VELOCITY; MOUSE; FLOW
AB The most commonly reported control used to minimize workplace exposures to nanomaterials is the chemical fume hood. Studies have shown, however, that significant releases of nanoparticles can occur when materials are handled inside fume hoods. This study evaluated the performance of a new commercially available nano fume hood using three different test protocols. Tracer gas, tracer nanoparticle, and nanopowder handling protocols were used to evaluate the hood. A static test procedure using tracer gas (sulfur hexafluoride) and nanoparticles as well as an active test using an operator handling nanoalumina were conducted. A commercially available particle generator was used to produce sodium chloride tracer nanoparticles. Containment effectiveness was evaluated by sampling both in the breathing zone (BZ) of a mannequin and operator as well as across the hood opening. These containment tests were conducted across a range of hood face velocities (60, 80, and 100 ft/min) and with the room ventilation system turned off and on. For the tracer gas and tracer nanoparticle tests, leakage was much more prominent on the left side of the hood (closest to the room supply air diffuser) although some leakage was noted on the right side and in the BZ sample locations. During the tracer gas and tracer nanoparticle tests, leakage was primarily noted when the room air conditioner was on for both the low and medium hood exhaust airflows. When the room air conditioner was turned off, the static tracer gas tests showed good containment across most test conditions. The tracer gas and nanoparticle test results were well correlated showing hood leakage under the same conditions and at the same sample locations. The impact of a room air conditioner was demonstrated with containment being adversely impacted during the use of room air ventilation. The tracer nanoparticle approach is a simple method requiring minimal setup and instrumentation. However, the method requires the reduction in background concentrations to allow for increased sensitivity.
C1 [Dunn, Kevin H.; Bennett, James S.; Garcia, Alberto; Ellenbecker, Michael J.] NIOSH, Div Appl Res & Technol, Engn & Phys Hazards Branch, Cincinnati, OH 45226 USA.
[Tsai, Candace Su-Jung] Purdue Univ, Sch Hlth Sci, W Lafayette, IN 47907 USA.
[Woskie, Susan R.] Univ Massachusetts, Coll Hlth Sci, Dept Work Environm, Lowell, MA USA.
RP Dunn, KH (reprint author), NIOSH, MS R5,1090 Tusculum Ave, Cincinnati, OH 45226 USA.
EM KDunn@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 22
TC 1
Z9 1
U1 3
U2 11
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 530 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 1545-9624
EI 1545-9632
J9 J OCCUP ENVIRON HYG
JI J. Occup. Environ. Hyg.
PY 2014
VL 11
IS 10
BP D164
EP D173
DI 10.1080/15459624.2014.933959
PG 10
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA AO0LX
UT WOS:000341001900003
PM 25175285
ER
PT J
AU Esswein, EJ
Snawder, J
King, B
Breitenstein, M
Alexander-Scott, M
Kiefer, M
AF Esswein, Eric J.
Snawder, John
King, Bradley
Breitenstein, Michael
Alexander-Scott, Marissa
Kiefer, Max
TI Evaluation of Some Potential Chemical Exposure Risks During Flowback
Operations in Unconventional Oil and Gas Extraction: Preliminary Results
SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE
LA English
DT Article
ID WORKERS
C1 [Esswein, Eric J.; King, Bradley; Kiefer, Max] NIOSH, Western States Off, Denver, CO 80225 USA.
[Snawder, John; Breitenstein, Michael; Alexander-Scott, Marissa] NIOSH, Div Appl Res & Technol, Cincinnati, OH 45226 USA.
RP Esswein, EJ (reprint author), NIOSH, Western States Off, Denver, CO 80225 USA.
EM eje1@cdc.gov
NR 19
TC 5
Z9 5
U1 0
U2 8
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 530 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 1545-9624
EI 1545-9632
J9 J OCCUP ENVIRON HYG
JI J. Occup. Environ. Hyg.
PY 2014
VL 11
IS 10
BP D174
EP D184
DI 10.1080/15459624.2014.933960
PG 11
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA AO0LX
UT WOS:000341001900004
PM 25175286
ER
PT J
AU Rahman, AM
Murrow, JR
Ozkor, MA
Kavtaradze, N
Lin, J
De Staercke, C
Hooper, WC
Manatunga, A
Hayek, S
Quyyumi, AA
AF Rahman, Ayaz M.
Murrow, Jonathan R.
Ozkor, Muhiddin A.
Kavtaradze, Nino
Lin, Ji
De Staercke, Christine
Hooper, W. Craig
Manatunga, Amita
Hayek, Salim
Quyyumi, Arshed A.
TI Endothelium-Derived Hyperpolarizing Factor Mediates
Bradykinin-Stimulated Tissue Plasminogen Activator Release in Humans
SO JOURNAL OF VASCULAR RESEARCH
LA English
DT Article
DE Bradykinin; Endothelium; Endothelium-derived hyperpolarizing factors;
Fibrinolysis; Tissue plasminogen activator
ID CORONARY-ARTERIES; HUMAN FOREARM; EPOXYEICOSATRIENOIC ACIDS; DEPENDENT
HYPERPOLARIZATION; CYTOCHROME P4502C9; TETRAETHYLAMMONIUM IONS;
MYOCARDIAL-INFARCTION; POTASSIUM CHANNELS; CIGARETTE-SMOKING;
HYDROGEN-PEROXIDE
AB Aims: Bradykinin (BK) stimulates tissue plasminogen activator (t-PA) release from human endothelium. Although BK stimulates both nitric oxide and endothelium-derived hyperpolarizing factor (EDHF) release, the role of EDHF in t-PA release remains unexplored. This study sought to determine the mechanisms of BK-stimulated t-PA release in the forearm vasculature of healthy human subjects. Methods: In 33 healthy subjects (age 40.3 +/- 1.9 years), forearm blood flow (FBF) and t-PA release were measured at rest and after intra-arterial infusions of BK (400 ng/min) and sodium nitroprusside (3.2 mg/min). Measurements were repeated after intra-arterial infusion of tetraethylammonium chloride (TEA; 1 mu mol/min), fluconazole (0.4 mu mol.min(-1).l(-1)), and N-G-monomethyl-L-arginine (L-NMMA, 8 mu mol/min) to block nitric oxide, and their combination in separate studies. Results: BK significantly increased net t-PA release across the forearm (p < 0.0001). Fluconazole attenuated both BK-mediated vasodilation (-23.3 +/- 2.7% FBF, p < 0.0001) and t-PA release (from 50.9 +/- 9.0 to 21.3 +/- 8.9 ng/min/100 ml, p = 0.02). TEA attenuated FBF (-14.7 +/- 3.2%, p = 0.002) and abolished BK-stimulated t-PA release (from 22.9 +/- 5.7 to -0.8 +/- 3.6 ng/min/100 ml, p = 0.0002). L-NMMA attenuated FBF (p < 0.0001), but did not inhibit BK-induced t-PA release (nonsignificant). Conclusion: BK-stimulated t-PA release is partly due to cytochrome P-450-derived epoxides and is inhibited by K-Ca(+) channel blockade. Thus, BK stimulates both EDHF-dependent vasodilation and t-PA release. (C) 2014 S. Karger AG, Basel
C1 [Rahman, Ayaz M.; Murrow, Jonathan R.; Ozkor, Muhiddin A.; Kavtaradze, Nino; Hayek, Salim; Quyyumi, Arshed A.] Emory Univ, Sch Med, Div Cardiol, Dept Med, Atlanta, GA 30322 USA.
[Lin, Ji; Manatunga, Amita] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA.
[De Staercke, Christine; Hooper, W. Craig] Ctr Dis Control & Prevent, Div Blood Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA USA.
RP Quyyumi, AA (reprint author), Emory Univ, Sch Med, 1462 Clifton Rd NE,Suite F506, Atlanta, GA 30322 USA.
EM aquyyum@emory.edu
OI Hayek, Salim/0000-0003-0180-349X
FU National Institutes of Health Research [RO1 HL79115]; Clinical and
Translational Science Award Program [UL1 RR025008]; General Clinical
Research Center program [M01 RR00039]; National Institutes of Health;
National Center for Research Resources; British Cardiovascular Society
Research Fellowship; National Blood Foundation; NIH NRSA Training Grant
[T32]; American College of Cardiology Foundation Keating Fellowship
FX The study was supported by National Institutes of Health Research Grant
RO1 HL79115, and in part by PHS Grant UL1 RR025008 from the Clinical and
Translational Science Award Program, and PHS Grant M01 RR00039 from the
General Clinical Research Center program, National Institutes of Health,
National Center for Research Resources, the British Cardiovascular
Society Research Fellowship, National Blood Foundation, NIH NRSA T32
Training Grant, American College of Cardiology Foundation Keating
Fellowship, and the American Heart Association Beginning Grant-in-Aid.
NR 57
TC 3
Z9 3
U1 0
U2 1
PU KARGER
PI BASEL
PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND
SN 1018-1172
EI 1423-0135
J9 J VASC RES
JI J. Vasc. Res.
PY 2014
VL 51
IS 3
BP 200
EP 208
DI 10.1159/000362666
PG 9
WC Physiology; Peripheral Vascular Disease
SC Physiology; Cardiovascular System & Cardiology
GA AO2PZ
UT WOS:000341169000004
PM 24925526
ER
PT S
AU Sejvar, J
AF Sejvar, James
BE Tselis, AC
Booss, J
TI Neuroepidemiology and the epidemiology of viral infections of the
nervous system
SO NEUROVIROLOGY
SE Handbook of Clinical Neurology
LA English
DT Article; Book Chapter
ID WEST-NILE-VIRUS; CREUTZFELDT-JAKOB-DISEASE; PROGRESSIVE MULTIFOCAL
LEUKOENCEPHALOPATHY; SUBACUTE SCLEROSING-PANENCEPHALITIS; HERPES-SIMPLEX
ENCEPHALITIS; HUMAN PRION DISEASES; TRANSMISSIBLE SPONGIFORM
ENCEPHALOPATHIES; IMMUNIZATION SAFETY DATA; ACUTE FLACCID PARALYSIS;
GUILLAIN-BARRE-SYNDROME
C1 [Sejvar, James] Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Div Vector Borne Infect Dis, Natl Ctr Zoonot Vectorborne & Enter Dis, Atlanta, GA 30333 USA.
RP Sejvar, J (reprint author), Ctr Dis Control & Prevent, Div High Consequence Pathogens & Pathol, Natl Ctr Emerging & Zoonot Infect Dis, 1600 Clifton Rd,Mailstop A-39, Atlanta, GA 30333 USA.
EM zea3@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 113
TC 1
Z9 1
U1 0
U2 1
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0072-9752
BN 978-0-444-53488-0; 978-0-702-04539-4
J9 HAND CLINIC
PY 2014
VL 123
BP 67
EP 87
PG 21
WC Clinical Neurology
SC Neurosciences & Neurology
GA BB1EM
UT WOS:000341048300005
PM 25015481
ER
PT S
AU Sejvar, J
AF Sejvar, James
BE Tselis, AC
Booss, J
TI Vaccines and viral/toxin-associated neurologic infections
SO NEUROVIROLOGY
SE Handbook of Clinical Neurology
LA English
DT Article; Book Chapter
ID GUILLAIN-BARRE-SYNDROME; ACUTE NECROTIZING ENCEPHALOPATHY; IMMUNIZATION
PRACTICES ACIP; SUBACUTE SCLEROSING-PANENCEPHALITIS; ACUTE DISSEMINATED
ENCEPHALOMYELITIS; INFLUENZA-ASSOCIATED ENCEPHALOPATHY; TICK-BORNE
ENCEPHALITIS; CENTRAL-NERVOUS-SYSTEM; PREVENT HERPES-ZOSTER; PRACTICE
RESEARCH DATABASE
C1 [Sejvar, James] Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Div Vector Borne Infect Dis, Natl Ctr Zoonot Vectorborne & Enter Dis, Atlanta, GA 30333 USA.
RP Sejvar, J (reprint author), Ctr Dis Control & Prevent, Div High Consequence Pathogens & Pathol, Natl Ctr Emerging & Zoonot Infect Dis, 1600 Clifton Rd,Mailstop A-39, Atlanta, GA 30333 USA.
EM zea3@cdc.gov
NR 258
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0072-9752
BN 978-0-444-53488-0; 978-0-702-04539-4
J9 HAND CLINIC
PY 2014
VL 123
BP 719
EP 744
PG 26
WC Clinical Neurology
SC Neurosciences & Neurology
GA BB1EM
UT WOS:000341048300038
PM 25015514
ER
PT J
AU Zilversmit, L
Sappenfield, O
Zotti, M
McGehee, MA
AF Zilversmit, Leah
Sappenfield, Olivia
Zotti, Marianne
McGehee, Mary A.
TI Preparedness Planning for Emergencies Among Postpartum Women in Arkansas
During 2009
SO WOMENS HEALTH ISSUES
LA English
DT Article
ID HOUSEHOLD PREPAREDNESS; DISASTER PREPAREDNESS; HURRICANE-KATRINA;
HEALTH; POSTDISASTER; COMMUNICATION
AB Purpose: Having an emergency plan may reduce negative effects of disaster on the health of postpartum women and their infants. However, little is known about the prevalence of emergency plans among postpartum women. In 2009, Arkansas added a question to the Pregnancy Risk Assessment Monitoring System surveillance system about whether women who gave birth that year had an emergency plan. In this study, we first describe the sociodemographic characteristics, disaster experience, and region of residence of postpartum women in Arkansas who indicated that they had an emergency plan for their families in 2009, and second, examine associations between sociodemographic characteristics and disaster experience and the presence of an emergency plan.
Methods: Multivariable logistic regression (n = 1,173) was conducted to examine associations between maternal race/ethnicity, sociodemographic characteristics, region of residence, disaster experience, and having a disaster plan. We adjusted for maternal education, federal poverty level, and family size in our final model.
Findings: Forty-eight percent (n = 559) of women reported having an emergency plan. Hispanic women were less likely to report having a plan compared with non-Hispanic White women (n = 102 [10%]; adjusted prevalence ratio [aPR], 0.6; 95% confidence interval [CI], 0.4-0.9). Families with five or more members were more likely to have a plan compared with smaller families (n = 123 [11%]; aPR, 1.3; 95% CI, 1.1-1.6).
Conclusions: Policymakers and public health practitioners can use these results to promote emergency planning among postpartum women in Arkansas, with special outreach to postpartum women who are Hispanic or have smaller families. Copyright (C) 2014 by the Jacobs Institute of Women's Health. Published by Elsevier Inc.
C1 [Zilversmit, Leah; Sappenfield, Olivia; Zotti, Marianne] Ctr Dis Control & Prevent, Div Reprod Hlth, Appl Sci Branch, Atlanta, GA USA.
[McGehee, Mary A.] Ctr Publ Hlth Practice, Arkansas Dept Hlth, Hlth Stat Branch, Little Rock, AR USA.
RP Zilversmit, L (reprint author), 617 Viale Machiavelli Lane, Henderson, NV 89011 USA.
EM lzilver@gmail.com
NR 29
TC 2
Z9 2
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1049-3867
EI 1878-4321
J9 WOMEN HEALTH ISS
JI Womens Health Iss.
PD JAN-FEB
PY 2014
VL 24
IS 1
BP E83
EP E88
DI 10.1016/j.whi.2013.10.006
PG 6
WC Public, Environmental & Occupational Health; Women's Studies
SC Public, Environmental & Occupational Health; Women's Studies
GA AO1YW
UT WOS:000341112500013
PM 24439951
ER
PT J
AU Thienkrua, W
Todd, CS
Chaikummao, S
Sukwicha, W
Yafant, S
Tippanont, N
Varangrat, A
Khlaimanee, P
Holtz, TH
AF Thienkrua, Warunee
Todd, Catherine S.
Chaikummao, Supaporn
Sukwicha, Wichuda
Yafant, Somsak
Tippanont, Narongritt
Varangrat, Anchalee
Khlaimanee, Pechpailin
Holtz, Timothy H.
TI Prevalence and correlates of willingness to participate in a rectal
microbicide trial among men who have sex with men in Bangkok
SO AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV
LA English
DT Article
DE rectal microbicide; men who have sex with men; clinical trial; HIV;
prevention
ID PERU IMPLICATIONS; ANAL INTERCOURSE; LUBRICANT USE; GAY-MEN; HIV;
THAILAND; ACCEPTABILITY; GEL; INFECTION; SAFETY
AB Rectal microbicides (RMs) hold promise as a HIV prevention method to reduce transmission among men who have sex with men (MSM). To assess RM trial feasibility in Bangkok, we measured prevalence and correlates of willingness to participate among Thai MSM observational cohort participants. Between April 2006 and December 2010, 1744 MSM enrolled in the Bangkok MSM Cohort Study; at 12 months, RM trial participation willingness was measured. We evaluated correlates of RM trial participation willingness using logistic regression analysis. Participants completing the 12-month visit (81.4%, n = 1419) had a mean age of 27.3 years (SD = 6.1), and 65.5% and 86.1% reported having a steady partner or anal intercourse (AI) in the past four months, respectively. Most (79.1%, n = 1123) participants reported willingness to participate in an RM trial, which, in multivariable analysis, was independently associated with insertive only (adjusted odds ratio [AOR] = 3.25, 95% CI: 1.82-5.81) or receptive/versatile role AI (AOR = 3.07, 95% CI: 1.88-5.01), and being paid for sex (AOR = 12.15, 95% CI: 1.67-88.21) in the past four months, and believing that people with AIDS look sick (AOR = 1.92, 95% CI: 1.23-2.98). Of hypothetical RM trial features to increase enrollment likelihood, the most (91.1%) compelling was that the study be approved by the Thai ethics committee, followed by the study site offering evening hours (88.9%). Reasons not to participate were not wanting a rectal examination (29.5%) or fluid collected from the penis or anus (24.6%) and not wanting the placebo (23.0%). RM trial participation willingness was high, particularly for those with greater HIV acquisition risk, within this Thai MSM cohort, suggesting feasibility of an RM trial. Addressing potential barriers to trial entry may be useful in educational materials to optimize recruitment.
C1 [Thienkrua, Warunee; Chaikummao, Supaporn; Sukwicha, Wichuda; Yafant, Somsak; Tippanont, Narongritt; Varangrat, Anchalee; Khlaimanee, Pechpailin; Holtz, Timothy H.] Thailand MOPH US CDC Collaborat TUC, HIV STD Res Program, Nonthaburi, Thailand.
[Todd, Catherine S.] FHI 360, Asia Pacific Reg Off, Bangkok, Thailand.
[Holtz, Timothy H.] Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA USA.
RP Thienkrua, W (reprint author), Thailand MOPH US CDC Collaborat TUC, HIV STD Res Program, Nonthaburi, Thailand.
EM waruneet@cdc.gov
NR 34
TC 2
Z9 2
U1 1
U2 1
PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND
SN 0954-0121
EI 1360-0451
J9 AIDS CARE
JI Aids Care-Psychol. Socio-Med. Asp. Aids-Hiv
PY 2014
VL 26
IS 11
BP 1359
EP 1369
DI 10.1080/09540121.2014.913763
PG 11
WC Health Policy & Services; Public, Environmental & Occupational Health;
Psychology, Multidisciplinary; Respiratory System; Social Sciences,
Biomedical
SC Health Care Sciences & Services; Public, Environmental & Occupational
Health; Psychology; Respiratory System; Biomedical Social Sciences
GA AN2ZB
UT WOS:000340453500006
PM 24797186
ER
PT J
AU Yard, EE
Murphy, MW
Schneeberger, C
Narayanan, J
Hoo, E
Freiman, A
Lewis, LS
Hill, VR
AF Yard, Ellen E.
Murphy, Matthew W.
Schneeberger, Chandra
Narayanan, Jothikumar
Hoo, Elizabeth
Freiman, Alexander
Lewis, Lauren S.
Hill, Vincent R.
TI Microbial and chemical contamination during and after flooding in the
Ohio River-Kentucky, 2011
SO JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS
SUBSTANCES & ENVIRONMENTAL ENGINEERING
LA English
DT Article
DE Natural disaster; emergency response; floods
ID REAL-TIME PCR; TAP WATER SAMPLES; HURRICANE-KATRINA; SURFACE-WATER;
UNITED-STATES; NEW-ORLEANS; ULTRAFILTRATION; RECOVERY; FLOODWATER;
PATHOGENS
AB Surface water contaminants in Kentucky during and after 2011 flooding were characterized. Surface water samples were collected during flood stage (May 2-4, 2011; n = 15) and after (July 25-26, 2011; n = 8) from four different cities along the Ohio River and were analyzed for the presence of microbial indicators, pathogens, metals, and chemical contaminants. Contaminant concentrations during and after flooding were compared using linear and logistic regression. Surface water samples collected during flooding had higher levels of E. coli, enterococci, Salmonella, Campylobacter, E. coli O157:H7, adenovirus, arsenic, copper, iron, lead, and zinc compared to surface water samples collected 3-months post-flood (P < 0.05). These results suggest that flooding increases microbial and chemical loads in surface water. These findings reinforce commonly recommended guidelines to limit exposure to flood water and to appropriately sanitize contaminated surfaces and drinking wells after contamination by flood water.
C1 [Yard, Ellen E.; Murphy, Matthew W.; Lewis, Lauren S.] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Atlanta, GA USA.
[Yard, Ellen E.] Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA USA.
[Schneeberger, Chandra; Narayanan, Jothikumar; Hill, Vincent R.] Ctr Dis Control & Prevent, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA USA.
[Schneeberger, Chandra] IHRC Inc, Atlanta, GA USA.
[Hoo, Elizabeth; Freiman, Alexander] Kentucky Dept Publ Hlth, Div Publ Hlth Protect & Safety, Frankfort, KY USA.
[Hoo, Elizabeth; Freiman, Alexander] Kentucky Dept Publ Hlth, Div Epidemiol & Hlth Planing, Frankfort, KY USA.
[Hoo, Elizabeth] Ctr Dis Control & Prevent, Off Surveillance Epidemiol & Lab Serv, Atlanta, GA USA.
RP Yard, EE (reprint author), CDC NCEH HSB, 4770 Buford Hwy NE,MS F-60, Chamblee, GA 30341 USA.
EM eyard@cdc.gov
NR 35
TC 1
Z9 1
U1 4
U2 21
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 530 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 1093-4529
EI 1532-4117
J9 J ENVIRON SCI HEAL A
JI J. Environ. Sci. Health Part A-Toxic/Hazard. Subst. Environ. Eng.
PY 2014
VL 49
IS 11
BP 1236
EP 1243
DI 10.1080/10934529.2014.910036
PG 8
WC Engineering, Environmental; Environmental Sciences
SC Engineering; Environmental Sciences & Ecology
GA AN1UM
UT WOS:000340369200005
PM 24967556
ER
PT J
AU Dubey, P
Ghia, U
Turkevich, LA
AF Dubey, Prahit
Ghia, Urmila
Turkevich, Leonid A.
TI Numerical Investigation of Sheath and Aerosol Flows in the Flow
Combination Section of a Baron Fiber Classifier
SO AEROSOL SCIENCE AND TECHNOLOGY
LA English
DT Article
ID ALVEOLAR MACROPHAGES; GLASS-FIBERS; LENGTH; CYTOTOXICITY; ASBESTOS;
DIELECTROPHORESIS; CHRYSOTILE; DIMENSIONS; SEPARATION; WORKERS
AB The Baron fiber classifier is an instrument used to separate fibers by length. The flow combination section (FCS) of this instrument is an upstream annular region, where an aerosol of uncharged fibers is introduced along with two sheath flows; length separation occurs by dielectrophoresis downstream in the flow classification section. In its current implementation at NIOSH, the instrument is capable of processing only very small quantities of fibers. In order to prepare large quantities of length-separated fibers for toxicological studies, the throughput of the instrument needs to be increased, and hence, higher aerosol flow rates need to be considered. However, higher aerosol flow rates may give rise to flow separation or vortex formation in the FCS, arising from the sudden expansion of the aerosol at the inlet nozzle. The goal of the present investigation is to understand the interaction of the sheath and aerosol flows inside the FCS, using computational fluid dynamics (CFD), and to identify possible limits to increasing aerosol flow rates. Numerical solutions are obtained using an axisymmetric model of the FCS, and solving the Navier-Stokes equations governing these flows; in this study, the aerosol flow is treated purely aerodynamically. Results of computations are presented for four different flow rates. The geometry of the converging outer cylinder, along with the two sheath flows, is effective in preventing vortex formation in the FCS for aerosol-to-sheath flow inlet velocity ratios below similar to 50. For higher aerosol flow rates, recirculation is observed in both inner and outer sheaths. Results for velocity, streamlines, and shear stress are presented.
C1 [Dubey, Prahit; Ghia, Urmila] Univ Cincinnati, Dept Mech & Mat Engn, Coll Engn & Appl Sci, Cincinnati, OH USA.
[Turkevich, Leonid A.] Ctr Dis Control & Prevent, Chem Exposure & Monitoring Branch, Div Appl Res & Technol, NIOSH, Cincinnati, OH 45226 USA.
RP Turkevich, LA (reprint author), Ctr Dis Control & Prevent, Chem Exposure & Monitoring Branch, Div Appl Res & Technol, NIOSH, 4676 Columbia Pkwy, Cincinnati, OH 45226 USA.
EM LLT0@cdc.gov
FU NIOSH NORA program
FX This work was supported, in part, under the NIOSH NORA program.
NR 36
TC 0
Z9 0
U1 0
U2 2
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 530 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 0278-6826
EI 1521-7388
J9 AEROSOL SCI TECH
JI Aerosol Sci. Technol.
PY 2014
VL 48
IS 8
BP 896
EP 905
DI 10.1080/02786826.2014.936342
PG 10
WC Engineering, Chemical; Engineering, Mechanical; Environmental Sciences;
Meteorology & Atmospheric Sciences
SC Engineering; Environmental Sciences & Ecology; Meteorology & Atmospheric
Sciences
GA AM8RZ
UT WOS:000340146100011
PM 26388662
ER
PT J
AU Medley, A
Seth, P
Pathak, S
Howard, AA
DeLuca, N
Matiko, E
Mwinyi, A
Katuta, F
Sheriff, M
Makyao, N
Wanjiku, L
Ngare, C
Bachanas, P
AF Medley, Amy
Seth, Puja
Pathak, Sonal
Howard, Andrea A.
DeLuca, Nickolas
Matiko, Eva
Mwinyi, Abubakari
Katuta, Frieda
Sheriff, Mushin
Makyao, Neema
Wanjiku, Lucy
Ngare, Carol
Bachanas, Pamela
TI Alcohol use and its association with HIV risk behaviors among a cohort
of patients attending HIV clinical care in Tanzania, Kenya, and Namibia
SO AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV
LA English
DT Article
DE alcohol use; HIV/AIDS; HIV risk behavior; sub-Saharan Africa
ID SUB-SAHARAN AFRICA; ANTIRETROVIRAL THERAPY; SOUTH-AFRICA; DISEASE
PROGRESSION; CAPE-TOWN; MEDICATION ADHERENCE; SEXUAL-BEHAVIORS;
CONSUMPTION; INFECTION; UGANDA
AB This article describes the frequency of alcohol use among HIV-positive patients attending clinical care in sub-Saharan Africa and explores the association between alcohol use, medication adherence, and sexual risk behavior. Data from 3538 patients attending an HIV clinic in Kenya, Tanzania, or Namibia were captured through interview and medical record abstraction. Participants were categorized into three drinking categories: nondrinkers, nonharmful drinkers, and harmful/likely dependent drinkers. A proportional odds model was used to identify correlates associated with categories of alcohol use. Overall, 20% of participants reported alcohol use in the past 6 months; 15% were categorized as nonharmful drinkers and 5% as harmful/likely dependent drinkers. Participants who reported missing a dose of their HIV medications [adjusted odds ratio (AOR): 2.04, 95% confidence interval (CI): 1.67, 2.49]; inconsistent condom use (AOR: 1.49, 95% CI: 1.23, 1.79); exchanging sex for food, money, gifts, or a place to stay (AOR: 1.57, 95% CI: 1.06, 2.32); and having a sexually transmitted infection symptom (AOR: 1.40, 95% CI: 1.10, 1.77) were more likely to be categorized in the higher risk drinking categories. This research highlights the need to integrate alcohol screening and counseling into the adherence and risk reduction counseling offered to HIV-positive patients as part of their routine care. Moreover, given the numerous intersections between alcohol and HIV, policies that focus on reducing alcohol consumption and alcohol-related risk behavior should be integrated into HIV prevention, care, and treatment strategies.
C1 [Medley, Amy; Seth, Puja; DeLuca, Nickolas; Bachanas, Pamela] US Ctr Dis Control & Prevent, Div Global HIV AIDS, Atlanta, GA 30333 USA.
[Pathak, Sonal] ICF Int, Atlanta, GA USA.
[Howard, Andrea A.] Columbia Univ, Int Ctr AIDS Care & Treatment Programs ICAP, New York, NY USA.
[Matiko, Eva] US Ctr Dis Control & Prevent, Dar Es Salaam, Tanzania.
[Mwinyi, Abubakari] Columbia Univ, Int Ctr AIDS Care & Treatment Programs ICAP, Dar Es Salaam, Tanzania.
[Katuta, Frieda] Minist Hlth & Social Serv, Windhoek, Namibia.
[Sheriff, Mushin] Columbia Univ, Int Ctr AIDS Care & Treatment Programs ICAP, Nairobi, Kenya.
[Makyao, Neema] Minist Hlth & Social Welf, Dar Es Salaam, Tanzania.
[Wanjiku, Lucy] US Ctr Dis Control & Prevent, Nairobi, Kenya.
[Ngare, Carol] Natl AIDS STD Control Programme NASCOP, Nairobi, Kenya.
RP Medley, A (reprint author), US Ctr Dis Control & Prevent, Div Global HIV AIDS, Atlanta, GA 30333 USA.
EM amedley@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 55
TC 6
Z9 7
U1 0
U2 1
PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND
SN 0954-0121
EI 1360-0451
J9 AIDS CARE
JI Aids Care-Psychol. Socio-Med. Asp. Aids-Hiv
PY 2014
VL 26
IS 10
BP 1288
EP 1297
DI 10.1080/09540121.2014.911809
PG 10
WC Health Policy & Services; Public, Environmental & Occupational Health;
Psychology, Multidisciplinary; Respiratory System; Social Sciences,
Biomedical
SC Health Care Sciences & Services; Public, Environmental & Occupational
Health; Psychology; Respiratory System; Biomedical Social Sciences
GA AM8NJ
UT WOS:000340132300013
PM 24773163
ER
PT J
AU Djawe, K
Brown, EEJ
Gaul, Z
Sutton, M
AF Djawe, Kpandja
Brown, Emma E. J.
Gaul, Zaneta
Sutton, Madeline
TI Community-based electronic data collections for HIV prevention research
with black/African-American men in the rural, Southern USA
SO AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV
LA English
DT Article
DE ACASI; feasibility; low-income; rural; HIV; black men
ID ASSISTED SELF-INTERVIEW; SEXUAL-BEHAVIOR; AUDIO; ACASI; ACCEPTABILITY;
POPULATION; ATTITUDES; MODES; YOUTH
AB In Florida, the HIV case rate among black men is five times that of white men; tailored HIV prevention interventions are lacking. Historical concerns regarding trust with public health venues and sharing sensitive information make face-to-face data collection with some rural, southern black men challenging. We evaluated the feasibility and acceptability of using audio computer-assisted self-interviews (ACASIs) by local community-based organization members to collect HIV-related information from black men in rural settings. We used logistic regression to estimate associations between using ACASI and participants' sociodemographic characteristics. Of 636 men approached, 586 (92.0%) participated, 479 (81.7%) never completed a computer survey, and 287 (71%) of those reporting a preference preferred ACASI for future data collections. Increased age, past computer use, and sharing a household with someone were significantly associated with ACASI feasibility and acceptability. Using ACASI with black men in rural settings is feasible for HIV intervention research and disparity-reducing goals.
C1 [Djawe, Kpandja; Gaul, Zaneta; Sutton, Madeline] Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA 30333 USA.
[Brown, Emma E. J.] Res & Program Evaluat CHARM Inc, Lake City, FL USA.
[Gaul, Zaneta] ICF Int, Atlanta, GA USA.
RP Djawe, K (reprint author), Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA 30333 USA.
EM wgp6@cdc.gov
NR 46
TC 3
Z9 3
U1 0
U2 1
PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND
SN 0954-0121
EI 1360-0451
J9 AIDS CARE
JI Aids Care-Psychol. Socio-Med. Asp. Aids-Hiv
PY 2014
VL 26
IS 10
BP 1309
EP 1317
DI 10.1080/09540121.2014.911812
PG 9
WC Health Policy & Services; Public, Environmental & Occupational Health;
Psychology, Multidisciplinary; Respiratory System; Social Sciences,
Biomedical
SC Health Care Sciences & Services; Public, Environmental & Occupational
Health; Psychology; Respiratory System; Biomedical Social Sciences
GA AM8NJ
UT WOS:000340132300016
PM 24773187
ER
PT J
AU Esona, MD
Mijatovic-Rustempasic, S
Yen, C
Parashar, UD
Gentsch, JR
Bowen, MD
LaRussa, P
AF Esona, Mathew D.
Mijatovic-Rustempasic, Slavica
Yen, Catherine
Parashar, Umesh D.
Gentsch, Jon R.
Bowen, Michael D.
LaRussa, Philip
TI Detection of PCV-2 DNA in stool samples from infants vaccinated with
RotaTeq (R)
SO HUMAN VACCINES & IMMUNOTHERAPEUTICS
LA English
DT Article
DE rotavirus vaccines; porcine circovirus; shedding; stool; DNA
ID HUMAN ROTAVIRUS VACCINE; CIRCOVIRUS TYPE-1 PCV1; PORCINE-CIRCOVIRUS;
CONTAMINATION; CHILDREN
AB Rotarix (R) and RotaTeq (R) vaccines have led to a dramatic reduction in rotavirus disease worldwide. However, the detection of porcine circovirus type 1 (PCV-1) and 2 (PCV-2) DNA in these vaccines raised some safety concerns. Studies examining shedding of rotavirus in stool from rotavirus vaccine recipients have been performed but no published data exist regarding the shedding of PCV virus in stools of vaccinees. The goal of this study was to determine if PCV-1 and/or PCV-2 is shed in the feces of infants vaccinated with RotaTeq (R). Using multiple PCR assays for detection of PCV DNA, we tested for PCV-1 and PCV-2 in 826 stool swab samples collected serially during the first 9 d after vaccination from 102 children vaccinated with RotaTeq (R). Since the vaccine is recommended and uptake is high, we did not have samples from unvaccinated infants. A total of 235 (28.5%) samples from 59 vaccine recipients were positive for PCV-2 DNA by one or more assays used in this study. PCV-1 DNA was not detected in RotaTeq (R) or any of the stool swab extracts. Twenty-two of the 102 vaccine recipients (21.6%) shed RotaTeq (R) vaccine strain and 10 of these vaccinees (9.8%) were shedding both PCV DNA and rotavirus vaccine RNA. PCV DNA was detected up to 9 d post vaccination and was most frequently detected in the first 5 d after vaccination. This study demonstrated shedding of PCV-2 DNA by RotaTeq (R) vaccinees but we did not find evidence that this DNA was associated with viable PCV. Findings from this study support the continued use of current rotavirus vaccines.
C1 [Esona, Mathew D.; Mijatovic-Rustempasic, Slavica; Yen, Catherine; Parashar, Umesh D.; Gentsch, Jon R.; Bowen, Michael D.] Ctr Dis Control & Prevent, Div Viral Dis, Natl Ctr Immunizat & Resp Dis, Atlanta, GA USA.
[Yen, Catherine; LaRussa, Philip] Columbia Univ, Coll Phys & Surg, New York, NY 10027 USA.
RP LaRussa, P (reprint author), Columbia Univ, Coll Phys & Surg, New York, NY 10027 USA.
EM plarussa@columbia.edu
NR 25
TC 6
Z9 6
U1 0
U2 3
PU LANDES BIOSCIENCE
PI AUSTIN
PA 1806 RIO GRANDE ST, AUSTIN, TX 78702 USA
SN 2164-5515
EI 2164-554X
J9 HUM VACC IMMUNOTHER
JI Human Vaccines Immunother.
PD JAN
PY 2014
VL 10
IS 1
BP 25
EP 32
DI 10.4161/hv.26731
PG 8
WC Biotechnology & Applied Microbiology; Immunology
SC Biotechnology & Applied Microbiology; Immunology
GA AH6RQ
UT WOS:000336258800004
PM 24104203
ER
PT J
AU Leung, J
Siegel, S
Jones, JF
Schulte, C
Blog, D
Schmid, DS
Bialek, SR
Marin, M
AF Leung, Jessica
Siegel, Subhadra
Jones, James F.
Schulte, Cynthia
Blog, Debra
Schmid, D. Scott
Bialek, Stephanie R.
Marin, Mona
TI Fatal varicella due to the vaccine-strain varicella-zoster virus
SO HUMAN VACCINES & IMMUNOTHERAPEUTICS
LA English
DT Article
DE varicella; VZV; varicella-zoster virus; vaccine-strain; vaccine adverse
event; acyclovir resistance
ID INFECTIOUS-DISEASES SOCIETY; HIV MEDICINE ASSOCIATION;
INSTITUTES-OF-HEALTH; KILLER T-CELLS; OPPORTUNISTIC INFECTIONS; SAFETY
PROFILE; UNITED-STATES; CHILD; ACYCLOVIR; RECOMMENDATIONS
AB We describe a death in a 15-mo-old girl who developed a varicella-like rash 20 d after varicella vaccination that lasted for 2 mo despite acyclovir treatment. The rash was confirmed to be due to vaccine-strain varicella-zoster virus (VZV). This is the first case of fatal varicella due to vaccine-strain VZV reported from the United States. The patient developed severe respiratory complications that worsened with each new crop of varicella lesions; vaccine-strain VZV was detected in the bronchial lavage specimen. Sepsis and multi-organ failure led to death. The patient did not have a previously diagnosed primary immune deficiency, but her failure to thrive and repeated hospitalizations early in life (starting at 5 mo) for presumed infections and respiratory compromise treated with corticosteroids were suggestive of a primary or acquired immune deficiency. Providers should monitor for adverse reactions after varicella vaccination. If severe adverse events develop, acyclovir should be administered as soon as possible. The possibility of acyclovir resistance and use of foscar-net should be considered if lesions do not improve after 10 d of treatment (or if they become atypical [e. g., verrucous]). Experience with use of varicella vaccine indicates that the vaccine has an excellent safety profile and that serious adverse events are very rare and mostly described in immunocompromised patients. The benefit of vaccination in preventing severe disease and mortality outweigh the low risk of severe events occurring after vaccination.
C1 [Leung, Jessica; Schmid, D. Scott; Bialek, Stephanie R.; Marin, Mona] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
[Siegel, Subhadra] New York Med Coll, Dept Pediat, New York, NY USA.
[Jones, James F.] Ctr Dis Control & Prevent, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA USA.
[Schulte, Cynthia; Blog, Debra] New York State Dept Hlth, Bur Immunizat, Albany, NY USA.
RP Leung, J (reprint author), Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
EM JLeung@cdc.gov
NR 34
TC 10
Z9 10
U1 0
U2 0
PU LANDES BIOSCIENCE
PI AUSTIN
PA 1806 RIO GRANDE ST, AUSTIN, TX 78702 USA
SN 2164-5515
EI 2164-554X
J9 HUM VACC IMMUNOTHER
JI Human Vaccines Immunother.
PD JAN
PY 2014
VL 10
IS 1
BP 146
EP 149
DI 10.4161/hv.26200
PG 4
WC Biotechnology & Applied Microbiology; Immunology
SC Biotechnology & Applied Microbiology; Immunology
GA AH6RQ
UT WOS:000336258800022
PM 23982221
ER
PT J
AU Caraballo, RS
Wang, X
Xu, X
AF Caraballo, Ralph S.
Wang, Xu
Xu, Xin
TI Can you refuse these discounts? An evaluation of the use and price
discount impact of price-related promotions among US adult smokers by
cigarette manufacturers
SO BMJ OPEN
LA English
DT Article
ID 4 COUNTRY SURVEY; SMOKING-CESSATION; PURCHASE PATTERNS; TOBACCO;
BEHAVIORS
AB Objectives: The raising unit price of cigarette has been shown to be one of the most effective ways of reducing cigarette consumption and increasing rates of successful quitting. However, researchers have shown that price-sensitive smokers have used a variety of strategies to mitigate the effect of the rising price of cigarettes on their smoking habits. In particular, 23-34% of adult smokers in the US use cheaper brands, and 18-55% use coupons or promotions. Little is known about the discount use by type of brands. As such, the main purpose of this analysis is to evaluate the uses and price discount effects of these price-related discounts by manufacturers and major brands.
Setting: An analysis based on the cross-sectional 2009-2010 National Adult Tobacco Survey (NATS).
Participants: 11 766 current smokers aged 18 or above in the USA.
Primary outcome measures: Price-related discount was defined as smokers who used coupons, rebates, buy-one-get-one-free, two-for-one or any other special promotions for their last cigarettes purchase.
Results: The use of price-related discounts and associated price impact vary widely by cigarette manufacturer and brand. Approximately one of three Camel, one of four Marlboro and one of eight Newport smokers used price-related discounts on their latest cigarette purchases. The average price reductions of discounts offered by Philip Morris (PM) or R.J. Reynolds (RJR) were around 29 cents per pack while that of Lorillard (Newport only) was 24 cents per pack. Cigarette brands that provided significant per pack price reductions include: PM Marlboro (28 cents), RJR brand Camel (41 cents), Doral (50 cents), Kool (73 cents) and Salem (80 cents), and Lorillard Newport (24 cents).
Conclusions: Policies that decrease price-minimisation strategies will benefit public health.
C1 [Caraballo, Ralph S.; Wang, Xu; Xu, Xin] Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Off Smoking & Hlth, Atlanta, GA 30333 USA.
RP Caraballo, RS (reprint author), Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Off Smoking & Hlth, Atlanta, GA 30333 USA.
EM rfc8@cdc.gov
NR 25
TC 4
Z9 4
U1 2
U2 4
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 2044-6055
J9 BMJ OPEN
JI BMJ Open
PY 2014
VL 4
IS 6
AR e004685
DI 10.1136/bmjopen-2013-004685
PG 7
WC Medicine, General & Internal
SC General & Internal Medicine
GA AM2YH
UT WOS:000339717100025
PM 24898086
ER
PT J
AU Spradling, PR
Hu, DJ
McMahon, BJ
AF Spradling, Philip R.
Hu, Dale J.
McMahon, Brian J.
BE Thomas, HC
Lok, ASF
Locarnini, SA
Zuckerman, AJ
TI Epidemiology and prevention
SO VIRAL HEPATITIS, 4TH EDITION
LA English
DT Article; Book Chapter
ID HEPATITIS-B-VIRUS; HEPATOCELLULAR-CARCINOMA; UNITED-STATES; INFECTION;
VACCINATION; GENOTYPE; CHILDREN; IMMUNITY; TAIWAN; AGE
AB Infection with hepatitis B virus (HBV) continues to be a leading cause of illness and death in many areas of the world. The prevalence of chronic infection among countries varies greatly and remains high in many parts of Asia and Africa. In developed countries, the prevalence is higher among those who emigrated from high- or intermediate-prevalence countries and among those with high-risk behaviors. Since the release of a highly effective vaccine in 1981, universal infant hepatitis B vaccination programs implemented in a growing number of countries have resulted in dramatic reductions in perinatal and chronic infection. Among persons vaccinated during adolescence and adulthood, studies demonstrate persistence of immunity for at least 20 years, and revaccination (or "booster doses") is not recommended. However, among persons vaccinated at birth, some data suggest loss of immunity in a significant proportion of persons after 15 years. Studies are ongoing to examine long-term immunity among persons who received hepatitis B vaccine at birth to determine if, when, and for whom revaccination may be warranted.
Hepatitis B virus (HBV) is a significant global pathogen. Approximately one-third of the world's population has been exposed to this virus, and 240 million persons are estimated to have chronic HBV infection. In the United States, the overall prevalence of chronic HBV infection is nearly 0.3%, but it is approximately 10% among persons born in countries in which hepatitis B is endemic. In this chapter, we review the epidemiology of hepatitis B in the United States and the rest of the world, including the routes of HBV transmission, groups and settings in which the risk of HBV infection is high, and HBV co-infection with other viruses. We also discuss prevention of HBV infection with hepatitis B vaccines and their global impact on this viral infection.
C1 [Spradling, Philip R.] Ctr Dis Control & Prevent, Div Viral Hepatitis, Atlanta, GA 30333 USA.
[Hu, Dale J.] US Embassy, US CDC Off, Int Emerging Infect Program, Beijing, Peoples R China.
[McMahon, Brian J.] Alaska Native Tribal Hlth Consortium, Liver Dis & Hepatitis Program, Anchorage, AK USA.
[McMahon, Brian J.] Ctr Dis Control & Prevent, Arctic Invest Program, Anchorage, AK USA.
RP Spradling, PR (reprint author), Ctr Dis Control & Prevent, Div Viral Hepatitis, Atlanta, GA 30333 USA.
NR 36
TC 1
Z9 1
U1 0
U2 0
PU BLACKWELL SCIENCE PUBL
PI OXFORD
PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND
BN 978-0-470-67295-2
PY 2014
BP 81
EP 95
PG 15
WC Gastroenterology & Hepatology; Infectious Diseases; Virology
SC Gastroenterology & Hepatology; Infectious Diseases; Virology
GA BA5VL
UT WOS:000337034100007
ER
PT J
AU Farley, JE
Landers, TF
Godfrey, C
Lipke, V
Sugarman, J
AF Farley, Jason E.
Landers, Timothy F.
Godfrey, Catherine
Lipke, Virginia
Sugarman, Jeremy
TI Optimizing the Protection of Research Participants and Personnel in
HIV-Related Research Where TB Is Prevalent: Practical Solutions for
Improving Infection Control
SO JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
LA English
DT Article
DE infection control; TB; HIV; clinical research; human subjects
protections; ethics
ID DRUG-RESISTANT TUBERCULOSIS; ISONIAZID PREVENTIVE THERAPY; HEALTH-CARE
WORKERS; SOUTH-AFRICA; PULMONARY TUBERCULOSIS; ANTIRETROVIRAL THERAPY;
MULTIDRUG-RESISTANT; TRANSMISSION; IMPLEMENTATION; DISINFECTION
AB Tuberculosis (TB) is a leading cause of death among persons with HIV globally. HIV-related research in TB endemic areas raises some unique and important ethical issues in infection control related to protecting both research participants and personnel. To address such concerns, this article provides practical guidance to help research teams develop strategies to prevent TB transmission in studies involving persons with HIV in TB endemic settings.
C1 [Farley, Jason E.] Johns Hopkins Univ, Sch Nursing, Dept Community & Publ Hlth, Baltimore, MD 21205 USA.
[Farley, Jason E.; Sugarman, Jeremy] Johns Hopkins Ctr AIDS Res CFAR, Baltimore, MD USA.
[Landers, Timothy F.] Ohio State Univ, Coll Nursing, Columbus, OH 43210 USA.
[Godfrey, Catherine] NIAID, NIH, Bethesda, MD 20892 USA.
[Lipke, Virginia] Ctr Dis Control & Prevent, Div Global HIV AIDS GAP, Atlanta, GA USA.
[Sugarman, Jeremy] Johns Hopkins Berman Inst Bioeth, Baltimore, MD USA.
[Sugarman, Jeremy] Johns Hopkins Univ, Sch Med, Baltimore, MD 21205 USA.
RP Farley, JE (reprint author), Johns Hopkins Univ, Sch Nursing, 525 N Wolfe St,Suite 525, Baltimore, MD 21205 USA.
EM jfarley1@jhu.edu
FU National Institutes of Health (NIH) [1P30AI094189]; NIH - National
Institute of Allergy and Infectious Disease; NIH - NCI; NIH - National
Institute of Child Health and Human Development; NIH - National Heart,
Lung, and Blood Institute; NIH - National Institute of Drug Abuse; NIH -
National Institute of Mental Health; NIH - National Institute on Aging;
NIH - FIC; NIH - OAR; National Institute of Allergy and Infectious
Disease; National Institute of Drug Abuse; National Institute of Mental
Health [UM1AI068619]
FX This publication proposal was made possible with help from the Johns
Hopkins University Center for AIDS Research, a National Institutes of
Health (NIH)-funded program (1P30AI094189), which is supported by the
following NIH cofunding and participating Institutes and Centers:
National Institute of Allergy and Infectious Disease, NCI, National
Institute of Child Health and Human Development, National Heart, Lung,
and Blood Institute, National Institute of Drug Abuse, National
Institute of Mental Health, National Institute on Aging, FIC, and OAR.
Work on this article was also supported in part by the National
Institute of Allergy and Infectious Disease, National Institute of Drug
Abuse and the National Institute of Mental Health under Cooperative
Agreement # UM1AI068619 to the HIV Prevention Trials Network.
NR 40
TC 2
Z9 2
U1 1
U2 13
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1525-4135
EI 1077-9450
J9 JAIDS-J ACQ IMM DEF
JI JAIDS
PD JAN 1
PY 2014
VL 65
SU 1
BP S19
EP S23
PG 5
WC Immunology; Infectious Diseases
SC Immunology; Infectious Diseases
GA AL3IF
UT WOS:000339019600006
PM 24321979
ER
PT J
AU Cassell, MM
Holtz, TH
Wolfe, MI
Hahn, M
Prybylski, D
AF Cassell, Michael M.
Holtz, Timothy H.
Wolfe, Mitchell I.
Hahn, Michael
Prybylski, Dimitri
TI 'Getting to zero' in Asia and the Pacific through more strategic use of
antiretrovirals for HIV prevention
SO SEXUAL HEALTH
LA English
DT Review
DE AIDS; at-risk populations; epidemic; pre-exposure prophylaxis; treatment
as prevention
ID SEXUALLY-TRANSMITTED INFECTIONS; HUMAN-IMMUNODEFICIENCY-VIRUS;
INJECTION-DRUG USERS; FEMALE SEX WORKERS; RANDOMIZED-TRIAL; CONDOM USE;
PREEXPOSURE PROPHYLAXIS; DEVELOPING-COUNTRIES; NEXT-GENERATION; RISK
BEHAVIORS
AB Encouraged by experimental trials demonstrating the efficacy of antiretrovirals (ARVs) in preventing HIV infection, countries across the Asia-Pacific region have committed to the achievement of ambitious targets tantamount to ending AIDS. The available data suggest that some countries still can make progress through targeted condom promotion and the expansion of harm-reduction interventions, but that none may realise its vision of 'zero new HIV infections' without more strategic use of ARVs as part of a combination of HIV prevention efforts targeting key populations. Low rates of HIV testing among men who have sex with men, people who inject drugs, sex workers and other key populations evidence low treatment coverage where treatment could have the greatest impact on curbing local epidemics. Studies have demonstrated the promise of adding ARV treatment and pre-exposure prophylaxis to the existing HIV prevention toolkit, but achieving population-level impact will require service-delivery approaches that overcome traditional prevention, care and treatment program distinctions. Priorities include: (1) innovative strategies to reach, test, treat and retain in services the individuals most likely to acquire or transmit HIV; (2) task shifting and enhanced partnerships between the public sector and civil society; (3) improved 'cascade' data systems to assess and promote service uptake and retention; and (4) policy and financing reform to enhance HIV testing and treatment access among key populations.
C1 [Cassell, Michael M.] US Agcy Int Dev, Hanoi, Vietnam.
[Holtz, Timothy H.; Wolfe, Mitchell I.; Prybylski, Dimitri] Minist Publ Hlth, Dept Dis Control, Thailand Minist Publ Hlth US Ctr Dis Control & Pr, Nonthaburi 11000, Thailand.
[Holtz, Timothy H.] US Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA 30333 USA.
[Wolfe, Mitchell I.; Prybylski, Dimitri] US Ctr Dis Control & Prevent, Div Global HIV AIDS, Atlanta, GA 30333 USA.
[Hahn, Michael] Joint United Nations Programme HIV AIDS, Thailand Country Off, Pranakorn Bangkok 10200, Thailand.
RP Cassell, MM (reprint author), US Agcy Int Dev, 6th Floor,Tung Shing Sq,2 Ngo Quyen, Hanoi, Vietnam.
EM mcassell@usaid.gov
NR 102
TC 4
Z9 4
U1 6
U2 10
PU CSIRO PUBLISHING
PI CLAYTON
PA UNIPARK, BLDG 1, LEVEL 1, 195 WELLINGTON RD, LOCKED BAG 10, CLAYTON, VIC
3168, AUSTRALIA
SN 1448-5028
EI 1449-8987
J9 SEX HEALTH
JI Sex Health
PY 2014
VL 11
IS 2
BP 107
EP 118
DI 10.1071/SH13116
PG 12
WC Public, Environmental & Occupational Health; Infectious Diseases
SC Public, Environmental & Occupational Health; Infectious Diseases
GA AL3CD
UT WOS:000339002000004
PM 24942266
ER
PT S
AU Hamner, HC
Tinker, SC
AF Hamner, Heather C.
Tinker, Sarah C.
BE PenaRosas, JP
GarciaCasal, MN
Pachon, H
TI Fortification of corn masa flour with folic acid in the United States:
an overview of the evidence
SO TECHNICAL CONSIDERATIONS FOR MAIZE FLOUR AND CORN MEAL FORTIFICATION IN
PUBLIC HEALTH
SE Annals of the New York Academy of Sciences
LA English
DT Article; Proceedings Paper
CT World-Health-Organization Consultation on Technical Considerations for
Fortification of Maize Flour and Corn Meal in Public Health
CY APR 08-09, 2013
CL New York Acad Sci, New York, NY
SP World Hlth Org, Flour Fortificat Initiat
HO New York Acad Sci
DE fortification; corn masa flour; folic acid
ID NEURAL-TUBE DEFECTS; NUTRITION EXAMINATION SURVEY; MEXICAN-AMERICAN
WOMEN; ACCULTURATION FACTORS; POTENTIAL IMPACT; NATIONAL-HEALTH;
PREVENTION; POPULATION; VITAMIN; FOLATE
AB Corn masa flour, used to make products such as corn tortillas, is a staple food for Hispanic populations residing in the United States, particularly among Mexican Americans and Central Americans. Research has indicated that Hispanic women in the United States continue to be at a higher risk of having a neural tube defect-affected pregnancy than women of other races/ethnicities, even after the introduction of folic acid fortification of cereal grain products labeled as "enriched." Corn masa flour has, therefore, been suggested as a potential food vehicle for folic acid in the United States. This paper explores the potential impact that folic acid fortification of corn masa flour could have on the Hispanic population in the United States.
C1 [Hamner, Heather C.; Tinker, Sarah C.] Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USA.
RP Hamner, HC (reprint author), Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, 1600 Clifton Rd NE MS E-86, Atlanta, GA 30333 USA.
EM hfc2@cdc.gov
FU Sackler Institute for Nutrition Science at the New York Academy of
Sciences; FFI
FX The findings and conclusions in this report are those of the authors and
do not necessarily represent the official position of the Centers for
Disease Control and Prevention. This article was presented at the World
Health Organization consultation "Technical Considerations for Maize
Flour and Corn Meal Fortification in PublicHealth" in collaboration with
the Sackler Institute for Nutrition Science at the New York Academy of
Sciences and the Flour Fortification Initiative (FFI), convened on 8 and
9 April 2013, at the New York Academy of Sciences in New York, USA. This
article is being published individually but will be consolidated with
other articles as a special issue of Annals of the New York Academy of
Sciences. The coordinators of this issue were Drs. Maria Nieves
Garcia-Casal, Mireille McLean, Helena Pachon, and Juan Pablo Pena-Rosas.
The special issue is the responsibility of the editorial staff of Annals
of the New York Academy of Sciences, who delegated to the coordinators
preliminary supervision of both technical conformity to the publishing
requirements of Annals of the New York Academy of Sciences and general
oversight of the scientific merit of each article. The workshop was
supported by the Sackler Institute for Nutrition Science at the New York
Academy of Sciences and the FFI. The authors alone are responsible for
the views expressed in this article; they do not necessarily represent
the views, decisions, or policies of the institutions with which they
are affiliated or the decisions, policies, or views of the World Health
Organization. The opinions expressed in this publication are those of
the authors and are not attributable to the sponsors, publisher, or
editorial staff of Annals of the New York Academy of Sciences.
NR 32
TC 4
Z9 4
U1 3
U2 17
PU BLACKWELL SCIENCE PUBL
PI OXFORD
PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND
SN 0077-8923
J9 ANN NY ACAD SCI
JI Ann.NY Acad.Sci.
PY 2014
VL 1312
BP 8
EP 14
DI 10.1111/nyas.12325
PG 7
WC Food Science & Technology; Public, Environmental & Occupational Health;
Nutrition & Dietetics
SC Food Science & Technology; Public, Environmental & Occupational Health;
Nutrition & Dietetics
GA BA8PR
UT WOS:000338446900002
PM 24494975
ER
PT J
AU Bean, CJ
Hooper, WC
Ellingsen, D
DeBaun, MR
Sonderman, J
Blot, WJ
AF Bean, Christopher J.
Hooper, W. Craig
Ellingsen, Dorothy
DeBaun, Michael R.
Sonderman, Jennifer
Blot, William J.
TI Discordance between Self-Report and Genetic Confirmation of Sickle Cell
Disease Status in African-American Adults
SO PUBLIC HEALTH GENOMICS
LA English
DT Article
DE Genetic communication; Health literacy; Hemoglobin; Self-report; Sickle
cell disease
ID PUBLIC-HEALTH IMPLICATIONS; TRAIT; KNOWLEDGE; ATTITUDES; AWARENESS;
BELIEFS
AB Background: Sickle cell disease (SCD) is an autosornal recessive genetic disorder, with persons heterozygous for the mutation said to have the sickle cell trait (SCT). Serious adverse effects are mainly limited to those with SCD, but the distinction between disease and trait is not always clear to the general population. We sought to determine the accuracy of self-reported SCD when compared to genetic confirmation. Methods: From stratified random samples of Southern Community Cohort Study participants, we sequenced the beta-globin gene in 51 individuals reporting SCD and 75 individuals reporting no SCD. Results: The median age of the group selected was 53 years (range 40-69) with 29% male. Only 5.9% of the 51 individuals reporting SCD were confirmed by sequencing, with the remaining 62.7% having SCT, 5.9% having hemoglobin C trait, and 25.5% having neither SCD nor trait. Sequencing results of the 75 individuals reporting no SCD by contrast were 100% concordant with self-report. Conclusions: Misreporting of SCD is common in an older adult population, with most persons reporting SCD in this study being carriers of the trait and a sizeable minority completely unaffected. The results from this pilot survey support the need for increased efforts to raise community awareness and knowledge of SCD. (C) 2014 S. Karger AG, Basel
C1 [Bean, Christopher J.; Hooper, W. Craig; Ellingsen, Dorothy] Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, Div Blood Disorders, Atlanta, GA USA.
[DeBaun, Michael R.] Vanderbilt Meharry Matthew Walker Ctr Excellence, Nashville, TN 37208 USA.
[Blot, William J.] Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol, Nashville, TN 37232 USA.
[Sonderman, Jennifer; Blot, William J.] Int Epidemiol Inst, Rockville, MD USA.
RP Blot, WJ (reprint author), Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol, 1161 21st Ave S, Nashville, TN 37232 USA.
EM william.j.blot@vanderbilt.edu
FU Intramural CDC HHS [CC999999]; NCI NIH HHS [R01 CA092447]
NR 18
TC 3
Z9 3
U1 1
U2 4
PU KARGER
PI BASEL
PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND
SN 1662-4246
EI 1662-8063
J9 PUBLIC HEALTH GENOM
JI Pub. Health Genomics
PY 2014
VL 17
IS 3
BP 169
EP 172
DI 10.1159/000360260
PG 4
WC Genetics & Heredity; Public, Environmental & Occupational Health
SC Genetics & Heredity; Public, Environmental & Occupational Health
GA AK9NZ
UT WOS:000338755100006
PM 24685557
ER
PT J
AU Lopez, LM
Grimes, DA
Schulz, KF
Curtis, KM
Chen, M
AF Lopez, Laureen M.
Grimes, David A.
Schulz, Kenneth F.
Curtis, Kathryn M.
Chen, Mario
TI Steroidal contraceptives: effect on bone fractures in women
SO COCHRANE DATABASE OF SYSTEMATIC REVIEWS
LA English
DT Review
DE Bone Density [drug effects]; Bone Remodeling [drug effects];
Contraceptives, Oral, Hormonal [adverse effects; pharmacology];
Estrogens [pharmacology]; Fractures, Bone [chemically induced];
Medroxyprogesterone Acetate [adverse effects; pharmacology];
Premenopause; Progestins [pharmacology]; Randomized Controlled Trials as
Topic; Female; Humans
ID DEPOT MEDROXYPROGESTERONE ACETATE; COMBINED ORAL-CONTRACEPTIVES;
RANDOMIZED CONTROLLED-TRIAL; YOUNG FERTILE WOMEN; MINERAL DENSITY;
HORMONAL CONTRACEPTION; ADOLESCENT GIRLS; DOUBLE-BLIND; LEVONORGESTREL;
TURNOVER
AB Background
Steroidal contraceptive use has been associated with changes in bone mineral density in women. Whether such changes increase the risk of fractures later in life is not clear. Osteoporosis is a major public health concern. Age-related decline in bone mass increases the risk of fracture, especially of the spine, hip, and wrist. Concern about bone health influences the recommendation and use of these effective contraceptives globally.
Objectives
Our aim was to evaluate the effect of using hormonal contraceptives before menopause on the risk of fracture in women.
Search methods
Through April 2014, we searched for studies of fracture or bone health and hormonal contraceptives in MEDLINE, POPLINE, CENTRAL, EMBASE, and LILACS, as well as ClinicalTrials.gov and ICTRP. We examined reference lists of relevant articles for other trials. For the initial review, we wrote to investigators to find additional trials.
Selection criteria
Randomized controlled trials (RCTs) were considered if they examined fractures, bone mineral density (BMD), or bone turnover markers in women with hormonal contraceptive use prior to menopause. Eligible interventions included comparisons of a hormonal contraceptive with a placebo or with another hormonal contraceptive that differed in terms of drug, dosage, or regimen. They also included providing a supplement to one group.
Data collection and analysis
We assessed all titles and abstracts identified through the literature searches. Mean differences were computed using the inverse variance approach. For dichotomous outcomes, theMantel-Haenszel odds ratio (OR) was calculated. Both included the 95% confidence interval (CI) and used a fixed-effect model. Due to differing interventions, no trials could be combined for meta-analysis. We applied principles from GRADE to assess the evidence quality and address confidence in the effect estimates. In addition, a sensitivity analysis included trials that provided sufficient data for this review and evidence of at least moderate quality.
Main results
We found 19RCTs that met our eligibility criteria. Eleven trials compared different combined oral contraceptives (COCs) or regimens of COCs; five examined an injectable versus another injectable, implant, or IUD; two studied implants, and one compared the transdermal patch versus the vaginal ring. No trial had fracture as an outcome. BMD was measured in 17 studies and 12 trials assessed biochemical markers of bone turnover. Depot medroxyprogesterone acetate (DMPA) was associated with decreased bone mineral density (BMD). The placebo-controlled trials showed BMD increases for DMPA plus estrogen supplement and decreases for DMPA plus placebo supplement. COCs did not appear to negatively affect BMD, and some formulations had more positive effects than others. However, no COC trial was placebo-controlled. Where studies showed differences between groups in bone turnover markers, the results were generally consistent with those for BMD. For implants, the single-rod etonogestrel group showed a greater BMD decrease versus the two-rod levonorgestrel group but results were not consistent across all implant comparisons.
The sensitivity analysis included 11 trials providing evidence of moderate or high quality. Four trials involving DMPA showed some positive effects of an estrogen supplement on BMD, a negative effect of DMPA-subcutaneous on lumbar spine BMD, and a negative effect of DMPA on a bone formation marker. Of the three COC trials, one had a BMD decrease for the group with gestodene plus EE 15 mu g. Another indicated less bone resorption in the group with gestodene plus EE 30 mu g versus EE 20 mu g.
Authors' conclusions
Whether steroidal contraceptives influence fracture risk cannot be determined from existing information. The evidence quality was considered moderate overall, largely due to the trials of DMPA, implants, and the patch versus ring. The COC evidence varied in quality but was low overall. Many trials had small numbers of participants and some had large losses. Health care providers and women should consider the costs and benefits of these effective contraceptives. For example, injectable contraceptives and implants provide effective, long-term birth control yet do not involve a daily regimen. Progestin-only contraceptives are considered appropriate for women who should avoid estrogen due to medical conditions.
C1 [Lopez, Laureen M.] FHI 360, Clin Sci, Durham, NC 27701 USA.
[Grimes, David A.; Schulz, Kenneth F.] Univ N Carolina, Sch Med, Chapel Hill, NC USA.
[Schulz, Kenneth F.] FHI 360, Quantitat Sci, Durham, NC USA.
[Curtis, Kathryn M.] Ctr Dis Control & Prevent, Div Reprod Hlth, Atlanta, GA USA.
[Chen, Mario] FHI 360, Div Biostat, Durham, NC USA.
RP Lopez, LM (reprint author), FHI 360, Clin Sci, 359 Blackwell St,Suite 200, Durham, NC 27701 USA.
EM llopez@fhi360.org
FU National Institute of Child Health and Human Development, USA.; US
Agency for International Development, USA.
FX Internal sources; No sources of support supplied; External sources;
National Institute of Child Health and Human Development, USA.; Support
for conducting the review and updates at FHI 360 (through 2014); US
Agency for International Development, USA.
NR 76
TC 5
Z9 5
U1 3
U2 6
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1469-493X
EI 1361-6137
J9 COCHRANE DB SYST REV
JI Cochrane Database Syst Rev.
PY 2014
IS 6
AR CD006033
DI 10.1002/14651858.CD006033.pub5
PG 93
WC Medicine, General & Internal
SC General & Internal Medicine
GA AK3FM
UT WOS:000338308700022
PM 24960023
ER
PT J
AU Razzaghi, H
Tinker, SC
AF Razzaghi, Hilda
Tinker, Sarah C.
TI Seafood consumption among pregnant and non-pregnant women of
childbearing age in the United States, NHANES 1999-2006
SO FOOD & NUTRITION RESEARCH
LA English
DT Article
DE pregnant; fish; seafood; NHANES; mercury
ID MATERNAL FISH INTAKE; PROSPECTIVE COHORT; US COHORT; METHYLMERCURY;
EXPOSURE; OUTCOMES; CHILDREN; MERCURY; CHILDHOOD; COGNITION
AB Objectives: Long-chain polyunsaturated fatty acids found in seafood are essential for optimal neurodevelopment of the fetus. However, concerns about mercury contamination of seafood and its potential harm to the developing fetus have created uncertainty about seafood consumption for pregnant women. We compared fish and shellfish consumption patterns, as well as their predictors, among pregnant and non-pregnant women of childbearing age in the US.
Methods: Data from 1,260 pregnant and 5,848 non-pregnant women aged 16-49 years from the 1999 to 2006 National Health and Nutrition Examination Survey (NHANES) were analyzed. Frequency and type of seafood consumed and adjusted associations of multiple characteristics with seafood consumption were estimated for pregnant and non-pregnant women, separately. Time trends were also examined.
Results: There were no significant differences in the prevalence of fish or shellfish consumption, separately or combined, between pregnant and non-pregnant women using either the 30-day questionnaire or the Day 1, 24-h recall. Seafood consumption was associated with higher age, income, and education among pregnant and non-pregnant women, and among fish consumers these groups were more likely to consume >= 3 servings in the past 30 days. Tuna and shrimp were the most frequently reported fish and shellfish, respectively, among both pregnant and non-pregnant women. We observed no significant time trends.
Conclusion: There were no differences in seafood consumption between pregnant and non-pregnant women, and the factors related to seafood consumption were similar for both groups. Our data suggest that many women consume less than the recommended two servings of seafood a week.
C1 [Razzaghi, Hilda; Tinker, Sarah C.] CDC, Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USA.
[Razzaghi, Hilda] Oak Ridge Inst Sci & Educ, Oak Ridge, TN USA.
RP Razzaghi, H (reprint author), 1600 Clifton Rd,Mail Stop E86, Atlanta, GA 30345 USA.
EM hir2@cdc.gov
FU appointment to the Research Participation program for the Centers for
Disease Control and Prevention
FX H.R. was supported by an appointment to the Research Participation
program for the Centers for Disease Control and Prevention administered
by the Oak Ridge Institute for Science and Education through an
agreement between the Department of Energy and CDC.
NR 31
TC 1
Z9 1
U1 0
U2 6
PU CO-ACTION PUBLISHING
PI JARFALLA
PA RIPVAGEN 7, JARFALLA, SE-175 64, SWEDEN
SN 1654-6628
EI 1654-661X
J9 FOOD NUTR RES
JI Food Nutr. Res.
PY 2014
VL 58
AR 23287
DI 10.3402/fnr.v58.23287
PG 9
WC Food Science & Technology; Nutrition & Dietetics
SC Food Science & Technology; Nutrition & Dietetics
GA AK3UJ
UT WOS:000338349900001
ER
PT J
AU Lee, SJ
Tak, S
Alterman, T
Calvert, GM
AF Lee, Soo-Jeong
Tak, Sangwoo
Alterman, Toni
Calvert, Geoffrey M.
TI Prevalence of Musculoskeletal Symptoms Among Agricultural Workers in the
United States: An Analysis of the National Health Interview Survey,
2004-2008
SO JOURNAL OF AGROMEDICINE
LA English
DT Article
DE Agriculture; joint pain; low back pain; musculoskeletal symptoms;
national survey
ID BACK-PAIN; FARMERS; DISORDERS; RISK; SURVEILLANCE; ILLNESS; MIGRANT;
INJURY
AB Ergonomic risks from agricultural tasks can compromise musculoskeletal health of workers. This study estimated prevalence of musculoskeletal symptoms in a sample representing almost 2 million US agricultural industry workers. This study used National Health Interview Survey data from 2004 to 2008. Weighted prevalence was calculated by demographic and employment factors. Prevalence ratios were calculated using generalized linear models with the Poisson distribution assumption. Prevalence rates of low back and neck pain in the previous 3 months were 24.3% and 10.5%, respectively, among agricultural workers. Monthly prevalence of joint pain was 17.0% for hips/knees, 9.8% for shoulders, 9.5% for wrists/hands, 5.4% for elbows, and 4.7% for ankles/toes. Agricultural workers had a significantly higher prevalence of shoulder pain than all other industry workers (prevalence ratios [PR] = 1.28, 95% confidence interval [CI]: 1.02-1.61). This study provides detailed national estimates of musculoskeletal symptom prevalence to understand the burden and the need for intervention among agricultural workers.
C1 [Lee, Soo-Jeong] Univ Calif San Francisco, Sch Nursing, Dept Community Hlth Syst, San Francisco, CA 94143 USA.
[Tak, Sangwoo] Univ Calif Los Angeles, Sch Publ Hlth, Los Angeles, CA 90024 USA.
[Alterman, Toni; Calvert, Geoffrey M.] NIOSH, Div Surveillance Hazard Evaluat & Field Studies, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA.
RP Lee, SJ (reprint author), Univ Calif San Francisco, Sch Nursing, Dept Community Hlth Syst, 2 Koret Way,Suite N505, San Francisco, CA 94143 USA.
EM soo-jeong.lee@nursing.ucsf.edu
OI Alterman, Toni/0000-0003-1512-4367
NR 40
TC 3
Z9 3
U1 0
U2 6
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 530 WALNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 1059-924X
EI 1545-0813
J9 J AGROMEDICINE
JI J. Agromedicine
PY 2014
VL 19
IS 3
BP 268
EP 280
DI 10.1080/1059924X.2014.916642
PG 13
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AJ9FO
UT WOS:000338013300003
PM 24959759
ER
PT J
AU Lisko, JG
Stanfill, SB
Watson, CH
AF Lisko, Joseph G.
Stanfill, Stephen B.
Watson, Clifford H.
TI Quantitation of ten flavor compounds in unburned tobacco products
SO ANALYTICAL METHODS
LA English
DT Article
ID CHROMATOGRAPHY-MASS SPECTROMETRY; COUMARIN; CAMPHOR; ALKENYLBENZENES;
CIGARETTES; MENTHOL; SMOKE
AB Most research on unburned tobacco has focused on the harmful chemicals associated with the tobacco itself. However, certain flavor additives in tobacco products can pose additional health risks. Flavors like camphor, coumarin, pulegone, eugenol, methyl salicylate, menthol and diphenyl ether have exhibited biological activity and/or toxicity in both lab animals and humans. This publication presents a new GC/MS method for the quantitation of ten flavor compounds (eucalyptol, camphor, menthol, pulegone, ethyl salicylate, methyl salicylate, cinnamaldehyde, eugenol, diphenyl ether and coumarin) in a variety of tobacco products, including smokeless products and cigar filler. Excellent linearity (>0.997), accuracy (93.9-106.6%) and precision (CV, 0.5-3.0%) were achieved for all flavor analytes measured. A summary of the concentrations of these flavors in selected international smokeless tobacco (SLT) products including zarda, quiwam, gutkha, and khaini varieties from Southeast Asia and snuff, clove cigarette filler and flavored cigar filler from the United States is reported. High concentrations of eugenol (2110 mu g g(-1)), coumarin (439 mu g g(-1)), camphor (1060 mu g g(-1)) and diphenyl ether (4840 mu g g(-1)) were found in selected products. Accurate identification and quantitation of potentially hazardous flavor compounds is important because they can exist in relatively high levels in some tobacco products, including international SLT products. We outline a versatile method which can be used to quantitate flavor compounds in multiple types of tobacco products.
C1 [Lisko, Joseph G.; Stanfill, Stephen B.; Watson, Clifford H.] Ctr Dis Control & Prevent, Tobacco & Volatiles Branch, Div Sci Lab, Natl Ctr Environm Hlth, Atlanta, GA 30341 USA.
RP Lisko, JG (reprint author), Ctr Dis Control & Prevent, Tobacco & Volatiles Branch, Div Sci Lab, Natl Ctr Environm Hlth, 4770 Buford Highway, Atlanta, GA 30341 USA.
EM jlisko@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 29
TC 5
Z9 6
U1 0
U2 14
PU ROYAL SOC CHEMISTRY
PI CAMBRIDGE
PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS,
ENGLAND
SN 1759-9660
EI 1759-9679
J9 ANAL METHODS-UK
JI Anal. Methods
PY 2014
VL 6
IS 13
BP 4698
EP 4704
DI 10.1039/c4ay00271g
PG 7
WC Chemistry, Analytical; Food Science & Technology; Spectroscopy
SC Chemistry; Food Science & Technology; Spectroscopy
GA AJ5XI
UT WOS:000337763200031
PM 26388954
ER
PT J
AU Wang, Y
Chen, AM
Dietrich, KN
Radcliffe, J
Caldwell, KL
Rogan, WJ
AF Wang, Yan
Chen, Aimin
Dietrich, Kim N.
Radcliffe, Jerilynn
Caldwell, Kathleen L.
Rogan, Walter J.
TI Postnatal exposure to methyl mercury and neuropsychological development
in 7-year-old urban inner-city children exposed to lead in the United
States
SO CHILD NEUROPSYCHOLOGY
LA English
DT Article
DE Methyl mercury; Lead; Postnatal exposure; Neuropsychological tests;
Cognition; IQ
ID PRENATAL METHYLMERCURY EXPOSURE; POLYUNSATURATED FATTY-ACIDS;
CHELATION-THERAPY; CHILDBEARING AGE; FISH CONSUMPTION; MATERNAL FISH; US
CHILDREN; BLOOD LEAD; PREGNANCY; NEURODEVELOPMENT
AB Background: The most common route for general population exposure to methyl mercury (MeHg) is fish consumption. Recommendations to pregnant women about consuming fish contaminated with MeHg are also applied to children, but there are few studies available about the effects of low-level postnatal MeHg exposure in them.Objectives: To investigate the association between postnatal methyl mercury exposure and neuropsychological development in a study of children also exposed to lead, both measured at 7 years.Methods: We measured MeHg concentrations in blood samples from the Treatment of Lead-Exposed Children (TLC) trial in which 780 children with elevated concentrations of lead in blood were followed with neuropsychological tests from ages 12-33 months through 7 years. Here we examine blood MeHg concentration and neuropsychological test scores, both measured at age 7 years. We used a maximum likelihood method to estimate geometric mean MeHg concentration and generalized linear regression models to analyze MeHg and neuropsychological test scores.Results: Geometric mean MeHg concentration was 0.56 (95% confidence interval: 0.52, 0.59) g/L. A1g/L increase in MeHg was associated with a 2.1 (95% confidence interval: 0.4, 3.8) point increase in Full-Scale IQ and 0.2 (95% confidence interval: 0.02, 0.4) point increase in Learning Slopeindex T-score on a test of verbal memory.Conclusions: Our results suggest that the relatively low MeHg exposure in US school-aged children from this population has no detectable adverse effect on neuropsychological development. The positive associations observed between MeHg and neurodevelopment may indirectly reflect consumption of beneficial polyunsaturated fatty acids from seafood.
C1 [Wang, Yan; Rogan, Walter J.] NIEHS, Epidemiol Branch, Res Triangle Pk, NC 27709 USA.
[Chen, Aimin; Dietrich, Kim N.] Univ Cincinnati, Coll Med, Div Epidemiol & Biostat, Dept Environm Hlth, Cincinnati, OH 45267 USA.
[Radcliffe, Jerilynn] Univ Penn, Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA.
[Caldwell, Kathleen L.] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Inorgan & Radiat Analyt Toxicol Branch, Atlanta, GA USA.
RP Dietrich, KN (reprint author), Univ Cincinnati, Coll Med, Div Epidemiol & Biostat, Dept Environm Hlth, 3223 Eden Ave,Room G-31,ML 056, Cincinnati, OH 45267 USA.
EM kim.dietrich@uc.edu
RI Rogan, Walter/I-6034-2012
OI Rogan, Walter/0000-0002-9302-0160
FU US National Institute of Environmental Health Sciences/National
Institutes of Health
FX This study was supported by the Intramural Research Program of the US
National Institute of Environmental Health Sciences/National Institutes
of Health. We thank Dr. Robert Jones, National Center for Environmental
Health of the CDC, for help with the measurement of Hg and the editorial
assistance of NIH Fellows Editorial Board.
NR 37
TC 2
Z9 2
U1 0
U2 7
PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND
SN 0929-7049
EI 1744-4136
J9 CHILD NEUROPSYCHOL
JI Child Neuropsychol.
PY 2014
VL 20
IS 5
BP 527
EP 538
DI 10.1080/09297049.2013.824955
PG 12
WC Clinical Neurology
SC Neurosciences & Neurology
GA AJ8QE
UT WOS:000337970600003
PM 23971942
ER
PT J
AU Margos, G
Piesman, J
Lane, RS
Ogden, NH
Sing, A
Straubinger, RK
Fingerle, V
AF Margos, Gabriele
Piesman, Joseph
Lane, Robert S.
Ogden, Nicholas H.
Sing, Andreas
Straubinger, Reinhard K.
Fingerle, Volker
TI Borrelia kurtenbachii sp nov., a widely distributed member of the
Borrelia burgdorferi sensu lato species complex in North America
SO INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
LA English
DT Article
ID MULTILOCUS SEQUENCE-ANALYSIS; LYME-DISEASE; BISSETTII; SURVEILLANCE;
INFECTION; GENETICS; REVEALS; STRAINS; CANADA
AB Lyme borreliosis group spirochaetes are parasitic bacteria transmitted by vector ticks of the genus lxodes and distributed mainly between 40 degrees and 60 degrees northern latitudes. Since Borrelia burgdorferi sensu stricto (hereinafter, B. burgdorferi) was described in the north-eastern USA during the early 1980s, an increasing diversity has been noted within the species complex. Here, we describe a novel genomic species, Borrelia kurtenbachii sp. nov. (type strain 25015(T)=ATCC BAA-2495(T)= DSM 26572(T)), that is prevalent in transmission cycles among vector ticks and reservoir hosts in North America. Confirmation of the presence of this species in Europe awaits further investigation.
C1 [Margos, Gabriele; Straubinger, Reinhard K.] Univ Munich, Dept Infect Dis & Zoonoses, Fac Vet Med, D-80359 Munich, Germany.
[Margos, Gabriele; Fingerle, Volker] Natl Reference Ctr Borrelia, D-85764 Oberschleissheim, Germany.
[Margos, Gabriele; Sing, Andreas; Fingerle, Volker] Bavarian Hlth & Food Safety Author, D-85764 Oberschleissheim, Germany.
[Piesman, Joseph] Ctr Dis Control & Prevent, Bacterial Dis Branch, Div Vector Borne Dis, Ft Collins, CO 80521 USA.
[Lane, Robert S.] Univ Calif Berkeley, Div Organisms & Environm, Dept Environm Sci Policy & Management, Berkeley, CA 94720 USA.
[Ogden, Nicholas H.] Publ Hlth Agcy Canada, Zoonoses Div, Ctr Food Borne Environm & Zoonot Infect Dis, Ottawa, ON, Canada.
RP Margos, G (reprint author), Univ Munich, Dept Infect Dis & Zoonoses, Fac Vet Med, Vet Str 13, D-80359 Munich, Germany.
EM gabriele.margos@lgl.bayern.de
OI Fingerle, Volker/0000-0002-3835-5646; Straubinger,
Reinhard/0000-0001-8382-7182
FU German National Reference Centre for Borrelia
FX The authors are grateful for continuous support by the Bavarian Ministry
for Environment and Health (StMUG) and the Robert Koch-Institut, Berlin,
Germany, for support of the German National Reference Centre for
Borrelia. In addition, the authors would like to thank D. Aanensen for
maintaining the Borrelia MLST website at Imperial College London, UK;
Nataljia Rudenko, Czech Academy of Sciences, and James Oliver of the
James H. Oliver, Jr. Institute of Arthropodology and Parasitology (IAP),
Georgia, USA, for sharing unpublished data.
NR 23
TC 15
Z9 15
U1 1
U2 9
PU SOC GENERAL MICROBIOLOGY
PI READING
PA MARLBOROUGH HOUSE, BASINGSTOKE RD, SPENCERS WOODS, READING RG7 1AG,
BERKS, ENGLAND
SN 1466-5026
EI 1466-5034
J9 INT J SYST EVOL MICR
JI Int. J. Syst. Evol. Microbiol.
PD JAN
PY 2014
VL 64
BP 128
EP 130
DI 10.1099/ijs.0.054593-0
PN 1
PG 3
WC Microbiology
SC Microbiology
GA AJ8CN
UT WOS:000337930400021
PM 24048870
ER
PT J
AU Fisher, EM
Shaffer, RE
AF Fisher, Edward M.
Shaffer, Ronald E.
TI Considerations for Recommending Extended Use and Limited Reuse of
Filtering Facepiece Respirators in Health Care Settings
SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE
LA English
DT Editorial Material
ID PERSONAL PROTECTIVE EQUIPMENT; INFLUENZA-VIRUS; N95 RESPIRATORS;
TRANSFER EFFICIENCY; INFECTION RISK; PANDEMIC H1N1; PARTICLE-SIZE;
SURVIVAL; BACTERIA; IMPACT
AB Public health organizations, such as the Centers for Disease Control and Prevention (CDC), are increasingly recommending the use of N95 filtering facepiece respirators (FFRs) in health care settings. For infection control purposes, the usual practice is to discard FFRs after close contact with a patient ("single use"). However, in some situations, such as during contact with tuberculosis patients, limited FFR reuse (i.e., repeated donning and doffing of the same FFR by the same person) is practiced. A related practice, extended use, involves wearing the same FFR for multiple patient encounters without doffing. Extended use and limited FFR reuse have been recommended during infectious disease outbreaks and pandemics to conserve FFR supplies. This commentary examines CDC recommendations related to FFR extended use and limited reuse and analyzes available data from the literature to provide a relative estimate of the risks of these practices compared to single use.
Analysis of the available data and the use of disease transmission models indicate that decisions regarding whether FFR extended use or reuse should be recommended should continue to be pathogen-and event-specific. Factors to be included in developing the recommendations are the potential for the pathogen to spread via contact transmission, the potential that the event could result in or is currently causing a FFR shortage, the protection provided by FFR use, human factors, potential for self-inoculation, the potential for secondary exposures, and government policies and regulations. While recent findings largely support the previous recommendations for extended use and limited reuse in certain situations, some new cautions and limitations should be considered before issuing recommendations in the future. In general, extended use of FFRs is preferred over limited FFR reuse. Limited FFR reuse would allow the user a brief respite from extended wear times, but increases the risk of self-inoculation and preliminary data from one study suggest that some FFR models may begin to lose effectiveness after multiple donnings.
C1 [Fisher, Edward M.; Shaffer, Ronald E.] NIOSH, Natl Personal Protect Technol Lab, Pittsburgh, PA 15236 USA.
RP Shaffer, RE (reprint author), NIOSH, Technol Res Branch, Natl Personal Protect Technol Lab, Ctr Dis Control & Prevent, 626 Cochrans Mill Rd,Bldg 20,POB 18070, Pittsburgh, PA 15236 USA.
EM RShaffer@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 100
TC 6
Z9 6
U1 1
U2 4
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 530 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 1545-9624
EI 1545-9632
J9 J OCCUP ENVIRON HYG
JI J. Occup. Environ. Hyg.
PY 2014
VL 11
IS 8
BP D115
EP D128
DI 10.1080/15459624.2014.902954
PG 14
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA AJ8IM
UT WOS:000337946700002
PM 24628658
ER
PT B
AU Weilharter, G
AF Weilharter, Gottfried
BE Scala, K
Grossmann, R
Lenglachner, M
Mayer, K
TI REFLECTIVE AND COMPETENT LEADERSHIP IN HOSPITALS THROUGH A
DIFFERENTIATED CONCEPT OF CONSULTING
SO LEADERSHIP LEARNING FOR THE FUTURE
SE Research in Management Education and Development
LA English
DT Article; Book Chapter
C1 CDC, Atlanta, GA 30333 USA.
RP Weilharter, G (reprint author), CDC, Atlanta, GA 30333 USA.
EM info@fritz-weilharter.at
NR 0
TC 0
Z9 0
U1 0
U2 0
PU INFORMATION AGE PUBLISHING-IAP
PI CHARLOTTE
PA PO BOX 79049, CHARLOTTE, NC 28271-7047 USA
BN 978-1-62396-460-3; 978-1-62396-461-0
J9 RES MANAG EDUC DEV
PY 2014
BP 319
EP 333
PG 15
WC Education & Educational Research; Management
SC Education & Educational Research; Business & Economics
GA BA5DL
UT WOS:000336555000023
ER
PT J
AU Brett, ME
Hinckley, AF
Zielinski-Gutierrez, EC
Mead, PS
AF Brett, Meghan E.
Hinckley, Alison F.
Zielinski-Gutierrez, Emily C.
Mead, Paul S.
TI U.S. healthcare providers' experience with Lyme and other tick-borne
diseases
SO TICKS AND TICK-BORNE DISEASES
LA English
DT Article
DE Tick-borne disease; Lyme disease; Treatment; Prophylaxis; Provider
knowledge
ID ERYTHEMA MIGRANS; ANTIBIOTIC-THERAPY; DIAGNOSIS; PREVENTION;
PROPHYLAXIS; MANAGEMENT; MISSOURI; BITES
AB Surveillance indicates that tick-borne diseases are a common problem in the United States. Nevertheless, little is known regarding the experience or management practices of healthcare providers who treat these conditions. The purpose of the present study was to characterize the frequency of tick-borne diseases in clinical practice and the knowledge of healthcare providers regarding their management. Four questions about tick-borne diseases were added to the 2009 Docstyles survey, a nationally representative survey of >2000 U.S. healthcare providers. Topics included diseases encountered, management of patients with early Lyme disease (LD), provision of tick-bite prophylaxis, and sources of information on tick-borne diseases. Overall, 51.3% of practitioners had treated at least one patient for a tick-borne illness in the previous year. Among these, 75.1% had treated one type of disease, 19.0% two types of disease, and 5.9% three or more diseases. LD was encountered by 936 (46.8%) providers; Rocky Mountain spotted fever was encountered by 184 (9.2%) providers. Given a scenario involving early LD, 89% of providers would prescribe antibiotics at the first visit, with or without ordering a blood test. Tick-bite prophylaxis was prescribed by 31.0% of all practitioners, including 41.1% in high-LD-incidence states and 26.0% in low-incidence states. Tick-borne diseases are encountered frequently in clinical practice. Most providers would treat early LD promptly, suggesting they are knowledgeable regarding the limitations of laboratory testing in this setting. Conversely, providers in low-LD-incidence states frequently prescribe tick-bite prophylaxis, suggesting a need for education to reduce potential misdiagnosis and overtreatment. Published by Elsevier GmbH.
C1 [Brett, Meghan E.; Hinckley, Alison F.; Zielinski-Gutierrez, Emily C.; Mead, Paul S.] Ctr Dis Control & Prevent, Div Vector Borne Dis, Ft Collins, CO 80521 USA.
RP Hinckley, AF (reprint author), Ctr Dis Control & Prevent, 3156 Rampart Rd, Ft Collins, CO 80521 USA.
EM ahinckley@cdc.gov
FU Centers for Disease Control and Prevention
FX This work was funded by the Centers for Disease Control and Prevention.
The views expressed in the publication are those of the authors and not
necessarily those of the U.S. government. The authors do not have any
conflicts of interest to disclose.
NR 24
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U1 1
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PU ELSEVIER GMBH, URBAN & FISCHER VERLAG
PI JENA
PA OFFICE JENA, P O BOX 100537, 07705 JENA, GERMANY
SN 1877-959X
EI 1877-9603
J9 TICKS TICK-BORNE DIS
JI Ticks Tick-Borne Dis.
PY 2014
VL 5
IS 4
BP 404
EP 408
DI 10.1016/j.ttbdis.2014.01.008
PG 5
WC Infectious Diseases; Microbiology; Parasitology
SC Infectious Diseases; Microbiology; Parasitology
GA AJ9BO
UT WOS:000338002000008
PM 24713280
ER
PT J
AU Krahn, GL
Horner-Johnson, W
Hall, TA
Roid, GH
Andresen, EM
Fujiura, GT
Nosek, MA
Cardinal, BJ
Drum, CE
Suzuki, R
Peterson, JJ
AF Krahn, Gloria L.
Horner-Johnson, Willi
Hall, Trevor A.
Roid, Gale H.
Andresen, Elena M.
Fujiura, Glenn T.
Nosek, Margaret A.
Cardinal, Bradley J.
Drum, Charles E.
Suzuki, Rie
Peterson, Jana J.
TI Development and Psychometric Assessment of the Function-Neutral
Health-Related Quality of Life Measure
SO AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
LA English
DT Article
DE Persons with Disability; Health Status; Environment; Quality-of-Life;
Questionnaires; Reliability; Validity
ID SELF-RATED HEALTH; SPINAL-CORD-INJURY; DISABILITY PARADOX; PERCEIVED
HEALTH; OUTCOMES; ADULTS; LIMITATIONS; ISSUES; SF-36
AB Objective: The aim of this study was to determine the conceptual framework, item pool, and psychometric properties of a new function-neutral measure of health-related quality-of-life (HRQOL).
Design: This is an expert panel review of existing measures of HRQOL and development of a conceptual model, core constructs, and item pool and a validation by experts in specific disabilities and in cultural competence. Items were cognitively tested, pilot tested for functional bias, field tested with a national sample of adults with various limitations, and reliability tested via repeat administration. Final item selection was based on analyses of factor structure, demographic bias, variance in likelihood of endorsement, and item-total correlation. Psychometric properties were demonstrated through differential item functioning analyses, factor analyses, correlations, and item response theory analyses.
Results: The results supported a four-domain conceptual model of HRQOL (physical health, mental health, social health, and life satisfaction and beliefs) for a 42-item HRQOL measure with an ancillary 15-item environment scale. The measure has strong internal consistency (alpha = 0.88-0.97), known-groups validity, and test-retest reliability (r = 0.83-0.91). Tests of convergent and divergent validity confirmed the ability of the Function-Neutral Health-Related Quality of Life to measure health while being relatively free of content assessing function.
Conclusions: A conceptually grounded four-domain, function-neutral measure of HRQOL that is appropriate for use with persons with and without various functional limitations was developed.
C1 [Krahn, Gloria L.; Horner-Johnson, Willi; Hall, Trevor A.; Drum, Charles E.; Suzuki, Rie; Peterson, Jana J.] Oregon Hlth & Sci Univ, Portland, OR 97201 USA.
[Roid, Gale H.] Warner Pacific Coll, Portland, OR USA.
[Andresen, Elena M.] Univ Florida, Gainesville, FL USA.
[Fujiura, Glenn T.] Univ Illinois, Chicago, IL USA.
[Nosek, Margaret A.] Baylor Coll Med, Houston, TX 77030 USA.
[Cardinal, Bradley J.] Oregon State Univ, Corvallis, OR 97331 USA.
RP Krahn, GL (reprint author), Ctr Dis Control & Prevent, Div Human Dev & Disabil, Natl Ctr Birth Defects & Dev Disabil, 1600 Clifton Rd NE,MS E88, Atlanta, GA 30333 USA.
OI Horner-Johnson, Willi/0000-0003-3568-1400
FU United States Department of Education, National Institute on Disability
and Rehabilitation Research (NIDRR) [H133B040034]
FX Supported by funds from the United States Department of Education,
National Institute on Disability and Rehabilitation Research (NIDRR),
under grant number H133B040034, principal investigator Gloria Krahn,
PhD, MPH, and project officer Phillip Beatty, PhD.
NR 51
TC 2
Z9 2
U1 1
U2 8
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0894-9115
EI 1537-7385
J9 AM J PHYS MED REHAB
JI Am. J. Phys. Med. Rehabil.
PD JAN
PY 2014
VL 93
IS 1
BP 56
EP 74
DI 10.1097/PHM.0b013e3182a517e6
PG 19
WC Rehabilitation; Sport Sciences
SC Rehabilitation; Sport Sciences
GA AJ5OZ
UT WOS:000337735800006
PM 24355997
ER
PT J
AU Le, D
Holt, CL
Pisu, M
Brown-Galvan, A
Fairley, TL
Smith, JL
White, A
Hall, IJ
Oster, RA
Martin, MY
AF Le, Daisy
Holt, Cheryl L.
Pisu, Maria
Brown-Galvan, Aquila
Fairley, Temeika L.
Smith, Judith Lee
White, Arica
Hall, Ingrid J.
Oster, Robert A.
Martin, Michelle Y.
TI The Role of Social Support in Posttreatment Surveillance Among African
American Survivors of Colorectal Cancer
SO JOURNAL OF PSYCHOSOCIAL ONCOLOGY
LA English
DT Article
DE colorectal cancer; African American; guidelines; surveillance;
colonoscopy; oncology
ID QUALITY-OF-LIFE; RELIGIOUS INVOLVEMENT; BREAST-CANCER;
RACIAL-DIFFERENCES; PHYSICAL HEALTH; FOLLOW-UP; CARE; SPIRITUALITY;
GUIDELINE; RECEIPT
AB African Americans are less likely than other groups to receive appropriate surveillance after colorectal cancer (CRC) treatment. The objective of this study is to qualitatively explore the role of social support in post-CRC treatment surveillance and ultimately, inform interventions to promote surveillance in African American survivors of CRC.
Interviews were conducted with 60 African American survivors of CRC recruited from the Cancer Care Outcomes Research and Surveillance (CanCORS) study and the Alabama Statewide Cancer Registry. Interviews were recorded and transcribed. Transcripts were reviewed and coded independently by the authors. The NVivo software package was used to facilitate coding and data management. Survivors were from 4 to 6 years post diagnosis, 57% female, 60% older than age 65 years, 57% from rural Alabama, 30% with stage 1, 32% with stage 2, and 38% with stage 3 disease. Material and emotional social support from family and one's faith community were cited as playing an important role in coping with the disease and posttreatment surveillance. Survivors who reported being adherent with posttreatment surveillance recommendations (according to stage of disease based on self-report of colonoscopy, computed tomography scans, and blood work) reported more religious material and non-material social support, and support from other survivors of CRC. In these African American survivors of CRC, support from family, other survivors of cancer, and the faith community was perceived as being important for adherence to posttreatment surveillance. Interventions to increase posttreatment surveillance in this population may be enhanced by including components that emphasize familial, other cancer survivor, and religious support.
C1 [Le, Daisy; Holt, Cheryl L.] Univ Maryland, Sch Publ Hlth, Dept Behav & Community Hlth, College Pk, MD 20742 USA.
[Pisu, Maria; Brown-Galvan, Aquila; Oster, Robert A.; Martin, Michelle Y.] Univ Alabama Birmingham, Dept Med, Div Prevent Med, Birmingham, AL 35294 USA.
[Pisu, Maria; Brown-Galvan, Aquila; Oster, Robert A.; Martin, Michelle Y.] Univ Alabama Birmingham, Ctr Comprehens Canc, Birmingham, AL 35294 USA.
[Fairley, Temeika L.; Smith, Judith Lee; White, Arica; Hall, Ingrid J.] Ctr Dis Control & Prevent, Div Canc Prevent & Control, Atlanta, GA USA.
RP Holt, CL (reprint author), Univ Maryland, Sch Publ Hlth, Dept Behav & Community Hlth, 2369 Public Hlth Bldg 255, College Pk, MD 20742 USA.
EM cholt14@umd.edu
FU NCI NIH HHS [U01 CA93326, U01 CA93344, U01 CA93332, U01 CA93339, U01
CA93324, U01 CA93348, R01 CA105202]; PHS HHS [U36/CCU319276 CFDA 93.283]
NR 57
TC 4
Z9 4
U1 2
U2 5
PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND
SN 0734-7332
EI 1540-7586
J9 J PSYCHOSOC ONCOL
JI J. Psychosoc. Oncol.
PY 2014
VL 32
IS 3
BP 245
EP 263
DI 10.1080/07347332.2014.897293
PG 19
WC Psychology, Social
SC Psychology
GA AJ3MK
UT WOS:000337570500001
PM 24611486
ER
PT J
AU Caruso, CC
AF Caruso, Claire C.
TI Negative Impacts of Shiftwork and Long Work Hours
SO REHABILITATION NURSING
LA English
DT Article
DE Shift work; occupational diseases; occupational injury; occupational
exposure; work schedule tolerance; circadian rhythms; job stress;
overtime work; extended work shifts; sleepiness
ID SHORT-SLEEP DURATION; HEALTH-CARE SECTOR; SCHEDULE CHARACTERISTICS;
PROSTATE-CANCER; MEDICAL ERRORS; HEART-DISEASE; UNITED-STATES;
RISK-FACTORS; NIGHT WORK; NURSES
AB Purpose: Healthcare organizations often have to provide patient care around the clock. Shift work (any shift outside of 7 a.m. to 6 p.m) and long work hours increase the risk for short sleep duration and sleep disturbances. Thirty-two percent of healthcare workers report they do not get enough sleep. The purpose of the article is to give an overview of the wide range of risks to nurses, patients, and employers that are linked to shift work, long work hours, and poor sleep from other sources.
Findings: Shift work and long work hours increase the risk for reduced performance on the job, obesity, injuries, and a wide range of chronic diseases. In addition, fatigue-related errors could harm patients. Fatigued nurses also endanger others during their commute to and from work.
Conclusion and Clinical Relevance: The key strategy to reduce these risks is making sleep a priority in the employer's systems for organizing work and in the nurse's personal life.
C1 NIOSH, Cincinnati, OH 45226 USA.
RP Caruso, CC (reprint author), NIOSH, 4676 Columbia Pkwy MS C-24, Cincinnati, OH 45226 USA.
EM ZHL1@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 78
TC 34
Z9 35
U1 8
U2 67
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0278-4807
EI 2048-7940
J9 REHABIL NURS
JI Rehabil. Nurs.
PD JAN-FEB
PY 2014
VL 39
IS 1
BP 16
EP 25
DI 10.1002/rnj.107
PG 10
WC Nursing; Rehabilitation
SC Nursing; Rehabilitation
GA AJ2SP
UT WOS:000337512500003
PM 23780784
ER
PT J
AU Hall, RM
Earnest, GS
Hammond, DR
Dunn, KH
Garcia, A
AF Hall, Ronald M.
Earnest, G. Scott
Hammond, Duane R.
Dunn, Kevin H.
Garcia, Alberto
TI A Summary of Research and Progress on Carbon Monoxide Exposure Control
Solutions on Houseboats
SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE
LA English
DT Article
AB Investigations of carbon monoxide (CO-related poisonings and deaths on houseboats were conducted by the Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health. These investigations measured hazardous CO concentrations on and around houseboats that utilize gasoline-powered generators. Engineering control devices were developed and tested to mitigate this deadly hazard. CO emissions were measured using various sampling techniques which included exhaust emission analyzers, detector tubes, evacuated containers (grab air samples analyzed by a gas chromatograph), and direct-reading CO monitors. CO results on houseboats equipped with gasoline-powered generators without emission controls indicated hazardous CO concentrations exceeding immediately dangerous to life and health (IDLH) levels in potentially occupied areas of the houseboat. Air sample results on houseboats that were equipped with engineering controls to remove the hazard were highly effective and reduced CO levels by over 98% in potentially occupied areas. The engineering control devices used to reduce the hazardous CO emissions from gasoline-powered generators on houseboats were extremely effective at reducing CO concentrations to safe levels in potentially occupied areas on the houseboats and are now beginning to be widely used.
C1 [Hall, Ronald M.; Earnest, G. Scott; Hammond, Duane R.; Dunn, Kevin H.; Garcia, Alberto] NIOSH, Div Appl Res & Technol, Engn & Phys Hazards Branch, Cincinnati, OH 45226 USA.
RP Hall, RM (reprint author), NIOSH, 4676 Columbia Pkwy, Cincinnati, OH 45226 USA.
EM rmhall@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 31
TC 0
Z9 0
U1 1
U2 5
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 530 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 1545-9624
EI 1545-9632
J9 J OCCUP ENVIRON HYG
JI J. Occup. Environ. Hyg.
PY 2014
VL 11
IS 7
BP D92
EP D100
DI 10.1080/15459624.2014.895374
PG 9
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA AI7SR
UT WOS:000337099200002
PM 24568306
ER
PT J
AU Fasula, AM
Carry, M
Miller, KS
AF Fasula, Amy M.
Carry, Monique
Miller, Kim S.
TI A Multidimensional Framework for the Meanings of the Sexual Double
Standard and its Application for the Sexual Health of Young Black Women
in the US
SO JOURNAL OF SEX RESEARCH
LA English
DT Article
ID AFRICAN-AMERICAN WOMEN; RANDOMIZED CONTROLLED-TRIAL; HETEROSEXUAL
COUPLES; ADOLESCENT GIRLS; CONDOM USE; PREVENTION INTERVENTION; GENDER
IDEOLOGIES; DECISION-MAKING; HIV PREVENTION; BODY-IMAGE
AB There has been debate in the literature as to whether a sexual double standard (SDS) currently exists in the United States. Studies vary greatly in how the SDS is operationalized, making it difficult to interpret findings across studies and translate academic literature into applied fields such as public health. To advance academic and applied research, we propose a multidimensional framework for the SDS that can accommodate complex and nuanced meanings, is flexible enough to allow for the dynamic nature of social ideologies, and is grounded in an understanding of social systems of inequality. In this article, we describe three dimensions that define the broad elements of the SDS: (a) polarized (hetero) sexualities, (b) active male and passive female roles, and (c) the power struggle narrative. To illustrate the use of the framework, we contextualize each dimension in terms of the intersection of race and gender for young Black women in the United States. And finally, to apply the framework, we explore the effects the SDS can have on sexual health and suggest some directions for public health interventions. These analyses lay the groundwork for more complex and comprehensive investigations of the SDS and its effects on sexual health.
C1 [Fasula, Amy M.; Carry, Monique; Miller, Kim S.] Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA 30333 USA.
RP Fasula, AM (reprint author), Ctr Dis Control & Prevent, Div HIV AIDS Prevent, 1600 Clifton Rd NE,Mail Stop E-37, Atlanta, GA 30333 USA.
EM afasula@cdc.gov
NR 110
TC 8
Z9 8
U1 4
U2 17
PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND
SN 0022-4499
EI 1559-8519
J9 J SEX RES
JI J. Sex Res.
PY 2014
VL 51
IS 2
BP 170
EP 183
DI 10.1080/00224499.2012.716874
PG 14
WC Psychology, Clinical; Social Sciences, Interdisciplinary
SC Psychology; Social Sciences - Other Topics
GA AI9CL
UT WOS:000337225300005
PM 23148703
ER
PT J
AU Hoffmann, M
Zhao, SH
Pettengill, J
Luo, Y
Monday, SR
Abbott, J
Ayers, SL
Cinar, HN
Muruvanda, T
Li, C
Allard, MW
Whichard, J
Meng, JH
Brown, EW
McDermott, PF
AF Hoffmann, Maria
Zhao, Shaohua
Pettengill, James
Luo, Yan
Monday, Steven R.
Abbott, Jason
Ayers, Sherry L.
Cinar, Hediye N.
Muruvanda, Tim
Li, Cong
Allard, Marc W.
Whichard, Jean
Meng, Jianghong
Brown, Eric W.
McDermott, Patrick F.
TI Comparative Genomic Analysis and Virulence Differences in Closely
Related Salmonella enterica Serotype Heidelberg Isolates from Humans,
Retail Meats, and Animals
SO GENOME BIOLOGY AND EVOLUTION
LA English
DT Article
DE outbreak; antimicrobial resistance; plasmid; SNP analysis; trace-back
ID IV SECRETION SYSTEMS; MULTILOCUS GENOTYPE DATA; SEROVAR HEIDELBERG;
ESCHERICHIA-COLI; UNITED-STATES; POPULATION-STRUCTURE;
CAENORHABDITIS-ELEGANS; PLASMID; DIVERSITY; EVOLUTION
AB Salmonella enterica subsp. enterica serovar Heidelberg (S. Heidelberg) is one of the top serovars causing human salmonellosis. Recently, an antibiotic-resistant strain of this serovar was implicated in a large 2011 multistate outbreak resulting from consumption of contaminated ground turkey that involved 136 confirmed cases, with one death. In this study, we assessed the evolutionary diversity of 44 S. Heidelberg isolates using whole-genome sequencing (WGS) generated by the 454 GS FLX (Roche) platform. The isolates, including 30 with nearly indistinguishable (one band difference) Xbal pulsed-field gel electrophoresis patterns (JF6X01.0032, JF6X01.0058), were collected from various sources between 1982 and 2011 and included nine isolates associated with the 2011 outbreak. Additionally, we determined the complete sequence for the chromosome and three plasmids from a clinical isolate associated with the 2011 outbreak using the Pacific Biosciences (PacBio) system. Using single-nucleotide polymorphism (SNP) analyses, we were able to distinguish highly clonal isolates, including strains isolated at different times in the same year. The isolates from the recent 2011 outbreak clustered together with a mean SNP variation of only 17 SNPs. The S. Heidelberg isolates carried a variety of phages, such as prophage P22, P4, lambda-like prophage Gifsy-2, and the P2-like phage which carries the sopE1 gene, virulence genes including 62 pathogenicity, and 13 fimbrial markers and resistance plasmids of the incompatibility (Inc)I1, IncA/C, and IncHI2 groups. Twenty-one strains contained an IncX plasmid carrying a type IV secretion system. On the basis of the recent and historical isolates used in this study, our results demonstrated that, in addition to providing detailed genetic information for the isolates, WGS can identify SNP targets that can be utilized for differentiating highly clonal S. Heidelberg isolates.
C1 [Hoffmann, Maria; Zhao, Shaohua; Abbott, Jason; Ayers, Sherry L.; Li, Cong; McDermott, Patrick F.] US FDA, Div Anim & Food Microbiol, Res Off, Ctr Vet Med, Laurel, MD 20708 USA.
[Hoffmann, Maria; Meng, Jianghong] Univ Maryland, Inst Food Safety & Appl Nutr, College Pk, MD 20742 USA.
[Pettengill, James; Luo, Yan] US FDA, Div Publ Hlth & Biostat, Off Food Def Commun & Emergency Response, Ctr Food Safety & Nutr, College Pk, MD USA.
[Monday, Steven R.; Muruvanda, Tim; Allard, Marc W.; Brown, Eric W.] US FDA, Div Microbiol, Off Regulatory Sci, Ctr Food Safety & Nutr, College Pk, MD USA.
[Cinar, Hediye N.] US FDA, Div Virulence Assessment, Off Appl Res & Safety Assessment, Ctr Food Safety & Nutr, Laurel, MD USA.
[Whichard, Jean] Ctr Dis Control & Prevent, Div Foodborne Waterborne & Environm Dis, Atlanta, GA USA.
RP Hoffmann, M (reprint author), US FDA, Div Anim & Food Microbiol, Res Off, Ctr Vet Med, Laurel, MD 20708 USA.
EM maria.hoffman@fda.hhs.gov; Patrick.McDermott@fda.hhs.gov
FU Center for Veterinary Medicine; Center for Food Safety and Applied
Nutrition at the US Food and Drug Administration; Joint Institute for
Food Safety and Applied Nutrition (JIFSAN), University of Maryland,
College Park, MD
FX The authors thank Ruth Timme for submission of the draft genomes to NCBI
and the NCBI rapid annotation pipeline team, Bill Klimke, Dmitry
Dernovoy, Stacy Ciufo, Kathleen O'Neill, Azat Badretdin, and Tatiana
Tatusova, for key genome annotation service. Further they thank Yuansha
Chen for sharing the CVM/DAFM database of antimicrobial resistance
genes. No human subjects or animals were used in this study. All authors
have read the manuscript and agreed to its contents, subject matter, and
author line order. These data are novel and have not been previously
published elsewhere. Disclosure forms provided by the authors will be
available with the full text of this article. This work was supported by
the Center for Veterinary Medicine and the Center for Food Safety and
Applied Nutrition at the US Food and Drug Administration and by an
appointment of MH by the Joint Institute for Food Safety and Applied
Nutrition (JIFSAN), University of Maryland, College Park, MD.
NR 64
TC 22
Z9 22
U1 0
U2 28
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1759-6653
J9 GENOME BIOL EVOL
JI Genome Biol. Evol.
PY 2014
VL 6
IS 5
BP 1046
EP 1068
DI 10.1093/gbe/evu079
PG 23
WC Evolutionary Biology; Genetics & Heredity
SC Evolutionary Biology; Genetics & Heredity
GA AI7BY
UT WOS:000337037100002
PM 24732280
ER
PT J
AU de Perio, MA
Niemeier, RT
AF de Perio, Marie A.
Niemeier, R. Todd
TI Evaluation of Exposure to Tuberculosis Among Employees at a Medical
Center
SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE
LA English
DT Article
ID HEALTH-CARE WORKERS; NOSOCOMIAL TRANSMISSION;
MYCOBACTERIUM-TUBERCULOSIS; UNSUSPECTED DISEASE; RISK; INFECTION;
OUTBREAK
C1 [de Perio, Marie A.] NIOSH, Div Surveillance Hazard Evaluat & Field Studies, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA.
[Niemeier, R. Todd] NIOSH, Educ & Informat Div, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA.
RP de Perio, MA (reprint author), NIOSH, Ctr Dis Control & Prevent, 4676 Columbia Pkwy,R-10, Cincinnati, OH 45226 USA.
EM mdeperio@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 18
TC 0
Z9 0
U1 0
U2 3
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 520 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA
SN 1545-9624
EI 1545-9632
J9 J OCCUP ENVIRON HYG
JI J. Occup. Environ. Hyg.
PY 2014
VL 11
IS 6
BP D63
EP D68
DI 10.1080/15459624.2014.888075
PG 6
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA AI7SO
UT WOS:000337098800001
PM 24499024
ER
PT J
AU Keck, JW
Redd, JT
Cheek, JE
Layne, LJ
Groom, AV
Kitka, S
Bruce, MG
Suryaprasad, A
Amerson, NL
Cullen, T
Bryan, RT
Hennessy, TW
AF Keck, James W.
Redd, John T.
Cheek, James E.
Layne, Larry J.
Groom, Amy V.
Kitka, Sassa
Bruce, Michael G.
Suryaprasad, Anil
Amerson, Nancy L.
Cullen, Theresa
Bryan, Ralph T.
Hennessy, Thomas W.
TI Influenza surveillance using electronic health records in the American
Indian and Alaska Native population
SO JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
LA English
DT Article
ID A H1N1; ILLNESS; RISK
AB Objective Increasing use of electronic health records (EHRs) provides new opportunities for public health surveillance. During the 2009 influenza A (H1N1) virus pandemic, we developed a new EHR-based influenza-like illness (ILI) surveillance system designed to be resource sparing, rapidly scalable, and flexible. 4 weeks after the first pandemic case, ILI data from Indian Health Service (IHS) facilities were being analyzed.
Materials and methods The system defines ILI as a patient visit containing either an influenza-specific International Classification of Disease, V. 9 (ICD-9) code or one or more of 24 ILI-related ICD-9 codes plus a documented temperature >= 100 degrees F. EHR-based data are uploaded nightly. To validate results, ILI visits identified by the new system were compared to ILI visits found by medical record review, and the new system's results were compared with those of the traditional US ILI Surveillance Network.
Results The system monitored ILI activity at an average of 60% of the 269 IHS electronic health databases. EHR-based surveillance detected ILI visits with a sensitivity of 96.4% and a specificity of 97.8% based on chart review (N=2375) of visits at two facilities in September 2009. At the peak of the pandemic (week 41, October 17, 2009), the median time from an ILI visit to data transmission was 6 days, with a mode of 1 day.
Discussion EHR-based ILI surveillance was accurate, timely, occurred at the majority of IHS facilities nationwide, and provided useful information for decision makers. EHRs thus offer the opportunity to transform public health surveillance.
C1 [Keck, James W.; Groom, Amy V.; Kitka, Sassa; Bruce, Michael G.; Suryaprasad, Anil; Amerson, Nancy L.; Bryan, Ralph T.; Hennessy, Thomas W.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Redd, John T.; Cheek, James E.; Layne, Larry J.; Cullen, Theresa] Indian Hlth Serv, Albuquerque, NM USA.
RP Redd, JT (reprint author), Santa Fe Indian Hosp, 1700 Cerrillos Rd, Santa Fe, NM 87508 USA.
EM john.redd@ihs.gov
NR 13
TC 3
Z9 3
U1 0
U2 3
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 1067-5027
EI 1527-974X
J9 J AM MED INFORM ASSN
JI J. Am. Med. Inf. Assoc.
PD JAN
PY 2014
VL 21
IS 1
BP 132
EP 138
DI 10.1136/amiajnl-2012-001591
PG 7
WC Computer Science, Information Systems; Computer Science,
Interdisciplinary Applications; Health Care Sciences & Services;
Information Science & Library Science; Medical Informatics
SC Computer Science; Health Care Sciences & Services; Information Science &
Library Science; Medical Informatics
GA AI2VK
UT WOS:000336716000020
PM 23744788
ER
PT J
AU Creanga, AA
Berg, CJ
Ko, JY
Farr, SL
Tong, VT
Bruce, FC
Callaghan, WM
AF Creanga, Andreea A.
Berg, Cynthia J.
Ko, Jean Y.
Farr, Sherry L.
Tong, Van T.
Bruce, F. Carol
Callaghan, William M.
TI Maternal Mortality and Morbidity in the United States: Where Are We Now?
SO JOURNAL OF WOMENS HEALTH
LA English
DT Article
ID PREGNANCY-RELATED MORTALITY; PREPREGNANCY OBESITY TRENDS; REPRODUCTIVE
AGE; WOMEN; HEALTH; DEPRESSION; INFLUENZA; DELIVERY; HOSPITALIZATIONS;
ASSOCIATION
AB This article provides a brief overview of the work conducted by the Division of Reproductive Health at the Centers for Disease Control and Prevention on severe maternal morbidity and mortality in the United States. The article presents the latest data and trends in maternal mortality and severe maternal morbidity, as well as on maternal substance abuse and mental health disorders during pregnancy, two relatively recent topics of interest in the Division, and includes future directions of work in all these areas.
C1 [Creanga, Andreea A.; Berg, Cynthia J.; Ko, Jean Y.; Farr, Sherry L.; Tong, Van T.; Bruce, F. Carol; Callaghan, William M.] Ctr Dis Control & Prevent, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA.
RP Creanga, AA (reprint author), Natl Ctr Chron Dis Prevent & Hlth Promot, Div Reprod Hlth, 4770 Buford Highway Northeast,Mail Stop K-23, Atlanta, GA 30341 USA.
EM acreanga@cdc.gov
OI Tong, Van/0000-0002-3970-1440
FU Intramural CDC HHS [CC999999]
NR 47
TC 51
Z9 51
U1 1
U2 7
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1540-9996
EI 1931-843X
J9 J WOMENS HEALTH
JI J. Womens Health
PD JAN
PY 2014
VL 23
IS 1
BP 3
EP 9
DI 10.1089/jwh.2013.4617
PG 7
WC Public, Environmental & Occupational Health; Medicine, General &
Internal; Obstetrics & Gynecology; Women's Studies
SC Public, Environmental & Occupational Health; General & Internal
Medicine; Obstetrics & Gynecology; Women's Studies
GA AI4BZ
UT WOS:000336811900002
PM 24383493
ER
PT J
AU Olsen, SJ
Kittikraisak, W
Fernandez, S
Suntarattiwong, P
Chotpitayasunondh, T
AF Olsen, Sonja J.
Kittikraisak, Wanitchaya
Fernandez, Stefan
Suntarattiwong, Piyarat
Chotpitayasunondh, Tawee
TI Challenges With New Rapid Influenza Diagnostic Tests
SO PEDIATRIC INFECTIOUS DISEASE JOURNAL
LA English
DT Letter
C1 [Olsen, Sonja J.] Ctr Dis Control & Prevent, Influenza Div, Atlanta, GA 30333 USA.
[Olsen, Sonja J.; Kittikraisak, Wanitchaya] Thailand MOPH US CDC Collaborat, Influenza Program, Nonthaburi, Thailand.
[Fernandez, Stefan] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Suntarattiwong, Piyarat; Chotpitayasunondh, Tawee] Queen Sirikit Natl Inst Child Hlth, Bangkok, Thailand.
RP Olsen, SJ (reprint author), Ctr Dis Control & Prevent, Influenza Div, Atlanta, GA 30333 USA.
FU Intramural CDC HHS [CC999999]
NR 6
TC 2
Z9 2
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0891-3668
EI 1532-0987
J9 PEDIATR INFECT DIS J
JI Pediatr. Infect. Dis. J.
PD JAN
PY 2014
VL 33
IS 1
BP 117
EP 118
DI 10.1097/INF.0000000000000089
PG 4
WC Immunology; Infectious Diseases; Pediatrics
SC Immunology; Infectious Diseases; Pediatrics
GA AH9ZP
UT WOS:000336505700037
PM 24346605
ER
PT J
AU Ortiz, AP
Unger, ER
Munoz, C
Panicker, G
Tortolero-Luna, G
Soto-Salgado, M
Otero, Y
Suarez, E
Perez, CM
AF Ortiz, A. P.
Unger, E. R.
Munoz, C.
Panicker, G.
Tortolero-Luna, G.
Soto-Salgado, M.
Otero, Y.
Suarez, E.
Perez, C. M.
TI Cross-sectional study of HPV-16 infection in a population-based
subsample of Hispanic adults
SO BMJ OPEN
LA English
DT Article
DE EPIDEMIOLOGY
ID PAPILLOMAVIRUS TYPE-16 INFECTION; UNITED-STATES; ANTIBODY-RESPONSE;
SEROPREVALENCE; WOMEN; MEN; SEROEPIDEMIOLOGY; PREVALENCE; RISK; DNA
AB Objective This study aimed to estimate the prevalence and correlates of seropositivity to human papillomavirus (HPV)-16 in a subsample of adults who participated in the parent study Epidemiology of Hepatitis C in the adult population of Puerto Rico (PR). Setting The parent study was a population-based household survey aimed to estimate the seroprevalence of hepatitis C and other viral infections (hepatitis A, hepatitis B, HIV, and herpes simplex type 2) in PR (n=1654) between 2005 and 2008.
Participants A subsample of the last 450 consecutive adults aged 21-64years, recruited between February 2007 and January 2008, who participated in the parent study and agreed to participate in HPV testing.
Primary and secondary outcome measures The samples were tested by ELISA for HPV-16 viral-like particle-specific immunoglobulin G. Information on sociodemographic, health, and lifestyle characteristics was collected. Logistic regression modelling was used to estimate the prevalence odds ratio (POR) to assess factors associated to HPV-16 seropositivity.
Results Prevalence of seropositivity to HPV-16 was 11.3%. Seroprevalence was higher in women (15.8%) than men (5.6%; p=0.001). After adjusting for age and sex, ever smokers (POR 2.06, 95% CI 1.08 to 3.92) and participants with at least five lifetime sexual partners (POR 2.91, 95% CI 1.24 to 6.81) were more likely to be HPV-16 seropositive.
Conclusions HPV-16 seropositivity is similar to that reported in the USA (10.4%) for NHANES 2003-2004 participants, although different assays were used in these studies. While future studies should evaluate HPV seroprevalence using a larger population-based sample, our results highlight the need to further understand the burden of HPV infection and HPV-related malignancies in PR, population with a low vaccine uptake.
C1 [Ortiz, A. P.; Tortolero-Luna, G.] Univ Puerto Rico, Ctr Comprehens Canc, Canc Control & Populat Sci Program, San Juan, PR 00936 USA.
[Ortiz, A. P.; Munoz, C.; Suarez, E.; Perez, C. M.] Univ Puerto Rico, Grad Sch Publ Hlth, Dept Biostat & Epidemiol, San Juan, PR 00936 USA.
[Unger, E. R.; Panicker, G.] Ctr Dis Control & Prevent, Chron Viral Dis Branch, Atlanta, GA USA.
[Soto-Salgado, M.; Otero, Y.] Univ Puerto Rico, Sch Med, UPR MDACC Partnership Excellence Canc Res, San Juan, PR 00936 USA.
RP Ortiz, AP (reprint author), Univ Puerto Rico, Ctr Comprehens Canc, Canc Control & Populat Sci Program, San Juan, PR 00936 USA.
EM ana.ortiz7@upr.edu
FU NIH NIGMS MBRS-SCORE Programme [S06-GM08224]; NICHD/EARDA
[1G11HD046326]; MBRS-SCORE, National Institute of Allergy and Infectious
Diseases, National Institutes of Health [1 SC2 AI090922-01];
NIH/NCRR/RCMI/UPR [G12RR03051]; NCRR [U54-RR 026139-01A1]; NIMHD from
Training in Computational Genomic Epidemiology of Cancer, National
Institute of Cancer [8U54-MD 007587-03 5R25CA094186-07]; U54 Partnership
for Excellence in Cancer Research, National Cancer Institute
[U54CA96297, U54CA96300]
FX The project described was fully supported by S06-GM08224 from NIH NIGMS
MBRS-SCORE Programme, 1G11HD046326 from NICHD/EARDA and 1 SC2
AI090922-01 from MBRS-SCORE, National Institute of Allergy and
Infectious Diseases, National Institutes of Health. This study was
partially supported by G12RR03051 from NIH/NCRR/RCMI/UPR, NCRR Award
Number U54-RR 026139-01A1 & NIMHD Award Number 8U54-MD 007587-03
5R25CA094186-07 from Training in Computational Genomic Epidemiology of
Cancer, National Institute of Cancer and by U54CA96297, U54CA96300 from
U54 Partnership for Excellence in Cancer Research, National Cancer
Institute. The Centers for Disease Control and Prevention provided
support for HPV testing.
NR 25
TC 2
Z9 2
U1 0
U2 6
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 2044-6055
J9 BMJ OPEN
JI BMJ Open
PY 2014
VL 4
IS 2
AR e004203
DI 10.1136/bmjopen-2013-004203
PG 6
WC Medicine, General & Internal
SC General & Internal Medicine
GA AF1FF
UT WOS:000334459100081
PM 24496698
ER
PT J
AU Grzywacz, JG
Alterman, T
Gabbard, S
Shen, R
Nakamoto, J
Carroll, DJ
Muntaner, C
AF Grzywacz, Joseph G.
Alterman, Toni
Gabbard, Susan
Shen, Rui
Nakamoto, Jorge
Carroll, Daniel J.
Muntaner, Carles
TI Job Control, Psychological Demand, and Farmworker Health Evidence From
the National Agricultural Workers Survey
SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
LA English
DT Article
ID HIRED FARM-WORKERS; LATINO FARMWORKERS; MIGRANT FARMWORKERS;
NORTH-CAROLINA; MENTAL-HEALTH; SEASONAL FARMWORKERS; DEPRESSIVE
SYMPTOMS; PESTICIDE EXPOSURE; CARE UTILIZATION; UNITED-STATES
AB Objective: Improve understanding of the potential occupational health impact of how agricultural jobs are organized. Exposure to low job control, high psychological demands, and high job strain were hypothesized to have greater risk for poor self-rated physical health and elevated depressive symptoms. Methods: Cross-sectional data (N = 3691) obtained using the Work Organization and Psychosocial Factors module of the US National Agricultural Workers Survey fielded in 2009-2010. Results: More than one fifth (22.4%) of farmworkers reported fair/poor health, and 8.7% reported elevated depressive symptoms. High psychological demand was associated with increased risk of fair/poor health (odds ratio, 1.73; 95% confidence interval, 1.4 to 2.2) and elevated depressive symptoms (odds ratio, 2.6; 95% confidence interval, 1.9 to 3.8). Conclusions: The organization of work in field agriculture may pose risks for poor occupational health outcomes among a vulnerable worker population.
C1 [Grzywacz, Joseph G.] Oklahoma State Univ, Dept Human Dev & Family Sci, Tulsa, OK 74106 USA.
[Grzywacz, Joseph G.] Oklahoma State Univ, Ctr Family Resilience, Tulsa, OK 74106 USA.
[Alterman, Toni] NIOSH, Div Surveillance Hazard Evaluat & Field Studi, Cincinnati, OH 45226 USA.
[Gabbard, Susan; Nakamoto, Jorge] JBS Int, Aguirre Div, Burlingame, CA USA.
[Shen, Rui] Emergint Technol, Cincinnati, OH USA.
[Carroll, Daniel J.] US Dept Labor, Employment & Training Adm, Washington, DC 20210 USA.
[Muntaner, Carles] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada.
[Muntaner, Carles] Univ Toronto, Bloomberg Fac Nursing, Toronto, ON, Canada.
RP Grzywacz, JG (reprint author), Oklahoma State Univ, Dept Human Dev & Family Sci, 700 N Greenwood Ave,Main Hall 2120, Tulsa, OK 74106 USA.
EM joseph.grzywacz@okstate.edu
OI Alterman, Toni/0000-0003-1512-4367
NR 38
TC 6
Z9 6
U1 1
U2 19
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1076-2752
EI 1536-5948
J9 J OCCUP ENVIRON MED
JI J. Occup. Environ. Med.
PD JAN
PY 2014
VL 56
IS 1
BP 66
EP 71
DI 10.1097/JOM.0000000000000025
PG 6
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AH6MY
UT WOS:000336246200009
PM 24351891
ER
PT J
AU Beitsch, LM
Corso, LC
Davis, MV
Joly, BM
Kronstadt, J
Riley, WJ
AF Beitsch, Leslie M.
Corso, Liza C.
Davis, Mary V.
Joly, Brenda M.
Kronstadt, Jessica
Riley, William J.
TI Transforming Public Health Practice Through Accreditation (A User Guide
for the Special Accreditation Issue)
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Editorial Material
ID STATES
C1 [Beitsch, Leslie M.] Florida State Univ, Coll Med, Tallahassee, FL 32306 USA.
[Corso, Liza C.] Ctr Dis Control & Prevent, Off State Tribal Local & Terr Support, Atlanta, GA USA.
[Davis, Mary V.] Univ N Carolina, North Carolina Inst Publ Hlth, Chapel Hill Gillings Sch Global Publ Hlth, Chapel Hill, NC 27515 USA.
[Joly, Brenda M.] Univ So Maine, Grad Program Publ Hlth, Portland, ME 04103 USA.
[Kronstadt, Jessica] Publ Hlth Accreditat Board, Alexandria, VA USA.
[Riley, William J.] Arizona State Univ, Sch Sci Hlth Care Delivery, Coll Hlth Solut, Phoenix, AZ USA.
RP Beitsch, LM (reprint author), Florida State Univ, Coll Med, 1115 West Call St, Tallahassee, FL 32306 USA.
EM les.beitsch@med.fsu.edu
NR 9
TC 6
Z9 6
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
IS 1
BP 2
EP 3
DI 10.1097/PHH.0b013e3182a8ea1e
PG 2
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AG8TO
UT WOS:000335691300002
PM 24322676
ER
PT J
AU Monteiro, E
Fisher, JS
Daub, T
Zamperetti, MC
AF Monteiro, Erinn
Fisher, Jessica Solomon
Daub, Teresa
Zamperetti, Michelle Chuk
TI CDC/NACCHO Accreditation Support Initiative: Advancing Readiness for
Local and Tribal Health Department Accreditation
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Article
DE funding; tribal health departments; local health departments;
accreditation
AB Context: Health departments have various unique needs that must be addressed in preparing for national accreditation. These needs require time and resources, shortages that many health departments face. Objective: The Accreditation Support Initiative's goal was to test the assumption that even small amounts of dedicated funding can help health departments make important progress in their readiness to apply for and achieve accreditation. Design: Participating sites' scopes of work were unique to the needs of each site and based on the proposed activities outlined in their applications. Deliverables and various sources of data were collected from sites throughout the project period (December 2011-May 2012). Setting/Participants: Awardees included 1 tribal and 12 local health departments, as well as 5 organizations supporting the readiness of local and tribal health departments. Results: Sites dedicated their funding toward staff time, accreditation fees, completion of documentation, and other accreditation readiness needs and produced a number of deliverables and example documents. All sites indicated that they made accreditation readiness gains that would not have occurred without this funding. Conclusions: Preliminary evaluation data from the first year of the Accreditation Support Initiative indicate that flexible funding arrangements may be an effective way to increase health departments' accreditation readiness.
C1 [Monteiro, Erinn; Fisher, Jessica Solomon; Zamperetti, Michelle Chuk] Natl Assoc Cty & City Hlth Officials, Washington, DC 20036 USA.
[Daub, Teresa] Ctr Dis Control & Prevent, Dept Hlth, Div Publ Hlth Performance Improvement, Off State Tribal Local & Terr Support, Atlanta, GA USA.
Ctr Dis Control & Prevent, Syst Dev Branch, Div Publ Hlth Performance Improvement, Off State Tribal Local & Terr Support, Atlanta, GA USA.
RP Monteiro, E (reprint author), Natl Assoc Cty & City Hlth Officials, 1100 17th St NW,Ste 700, Washington, DC 20036 USA.
EM emonteiro@naccho.org
FU NCHM CDC HHS [HM08-805]
NR 8
TC 5
Z9 5
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
IS 1
BP 14
EP 19
DI 10.1097/PHH.0b013e3182a336f3
PG 6
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AG8TO
UT WOS:000335691300006
PM 24322680
ER
PT J
AU Marshall, D
Pyron, T
Jimenez, J
Coffman, J
Pearsol, J
Koester, D
AF Marshall, Donna
Pyron, Trina
Jimenez, Jennifer
Coffman, Joya
Pearsol, Jim
Koester, Deb
TI Improving Public Health Through State Health Improvement Planning: A
Framework for Action
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Article
DE SHIP Guidance and Resources; health improvement planning; state health
improvement planning; national accreditation
ID COMMUNITY-HEALTH
AB Background: State health improvement plans (SHIPs) identify priorities for making the greatest impacts on health promotion and disease prevention, specific to the needs of state populations. Both SHIPs and the state health assessments on which they are based are prerequisites for Public Health Accreditation Board national accreditation. Objective: To identify and evaluate existing SHIPs to develop guidance to support health departments in the state health improvement planning process. Design: In 2010, the Association of State and Territorial Health Officials (ASTHO) conducted a comprehensive search for existing SHIPs. A systematic evaluation of existing SHIPS was accomplished by means of primary source document review using a standardized data collection form. Using data derived from these SHIPs and guidance from a workgroup of practitioners, ASTHO developed the ASTHO SHIP Guidance and Resources (SHIP Guidance) Framework. Results: The search yielded 25 states (49%) having a SHIP completed or in progress. Fifteen states (29%) had no SHIP but had a Healthy People plan, and 10 states (20%) had no SHIP or Healthy People plan. No information was available for 1 state. Findings were reviewed, evaluated, and incorporated into the SHIP Guidance. The SHIP Guidance provides a framework for the implementation, monitoring, and evaluation of a SHIP process using 12 key steps. Conclusions: As public health/health care integration and accreditation readiness activity grows, multisector engagement through a SHIP will continue to be a priority for state public health and improving health outcomes. The SHIP Guidance provides a systematic, flexible approach for states conducting or updating state health assessments and SHIPs.
C1 [Marshall, Donna; Coffman, Joya] Assoc State & Terr Hlth Officials, Arlington, VA 22202 USA.
[Pearsol, Jim] Assoc State & Terr Hlth Officials, Publ Hlth Performance Team, Arlington, VA 22202 USA.
[Pyron, Trina] Ctr Dis Control & Prevent, Div Publ Hlth Performance Improvement, Off State Tribal Local & Terr Support, Atlanta, GA USA.
[Koester, Deb] Ctr Dis Control & Prevent, Carter Consulting Inc, Off State Tribal Local & Terr Support, Atlanta, GA USA.
[Jimenez, Jennifer] Publ Hlth Accreditat Board, Alexandria, VA USA.
RP Marshall, D (reprint author), Assoc State & Terr Hlth Officials, 2231 Crystal Dr,Ste 450, Arlington, VA 22202 USA.
EM dmarshall@astho.org
NR 10
TC 2
Z9 2
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
IS 1
BP 23
EP 28
DI 10.1097/PHH.0b013e3182a5a4b8
PG 6
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AG8TO
UT WOS:000335691300008
PM 24322682
ER
PT J
AU McLees, AW
Thomas, CW
Nawaz, S
Young, AC
Rider, N
Davis, M
AF McLees, Anita W.
Thomas, Craig W.
Nawaz, Saira
Young, Andrea C.
Rider, Nikki
Davis, Mary
TI Advances in Public Health Accreditation Readiness and Quality
Improvement: Evaluation Findings From the National Public Health
Improvement Initiative
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Article
DE performance management; performance standards; public health
accreditation; evaluation; quality improvement
ID DEPARTMENTS; SYSTEMS
AB Introduction: Continuous quality improvement is a central tenet of the Public Health Accreditation Board's (PHAB) national voluntary public health accreditation program. Similarly, the Centers for Disease Control and Prevention launched the National Public Health Improvement Initiative (NPHII) in 2010 with the goal of advancing accreditation readiness, performance management, and quality improvement (QI). Objective: Evaluate the extent to which NPHII awardees have achieved program goals. Design: NPHII awardees responded to an annual assessment and program monitoring data requests. Analysis included simple descriptive statistics. Setting: Seventy-four state, tribal, local, and territorial public health agencies receiving NPHII funds. Participants: NPHII performance improvement managers or principal investigators. Main Outcome Measure(s): Development of accreditation prerequisites, completion of an organizational self-assessment against the PHAB Standards and Measures, Version 1.0, establishment of a performance management system, and implementation of QI initiatives to increase efficiency and effectiveness. Results: Of the 73 responding NPHII awardees, 42.5% had a current health assessment, 26% had a current health improvement plan, and 48% had a current strategic plan in place at the end of the second program year. Approximately 26% of awardees had completed an organizational PHAB self-assessment, 72% had established at least 1 of the 4 components of a performance management system, and 90% had conducted QI activities focused on increasing efficiencies and/or effectiveness. Conclusions: NPHII appears to be supporting awardees' initial achievement of program outcomes. As NPHII enters its third year, there will be additional opportunities to advance the work of NPHII, compile and disseminate results, and inform a vision of high-quality public health necessary to improve the health of the population.
C1 [McLees, Anita W.; Thomas, Craig W.; Nawaz, Saira; Young, Andrea C.] Ctr Dis Control & Prevent, Off State Tribal Local & Terr Support, US Dept HHS, Atlanta, GA 30345 USA.
[Rider, Nikki] Natl Network Publ Hlth Inst, New Orleans, LA USA.
[Davis, Mary] Univ N Carolina, North Carolina Inst Publ Hlth, UNC Gillings Sch Global Publ Hlth, Chapel Hill, NC USA.
RP McLees, AW (reprint author), Ctr Dis Control & Prevent, Off State Tribal Local & Terr Support, 1825 Century Ctr MS E-70, Atlanta, GA 30345 USA.
EM zdu5@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 18
TC 11
Z9 11
U1 1
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
IS 1
BP 29
EP 35
DI 10.1097/PHH.0b013e31829ff726
PG 7
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AG8TO
UT WOS:000335691300009
PM 24322683
ER
PT J
AU Thomas, CW
Pietz, H
Corso, L
Erlwein, B
Monroe, J
AF Thomas, Craig W.
Pietz, Harald
Corso, Liza
Erlwein, Bobbie
Monroe, Judith
TI Advancing Accreditation Through the National Public Health Improvement
Initiative
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Article
C1 [Pietz, Harald] Ctr Dis Control & Prevent, Dept Hlth, Atlanta, GA 30329 USA.
[Pietz, Harald] Ctr Dis Control & Prevent, Syst Dev Branch, Atlanta, GA 30329 USA.
[Thomas, Craig W.; Corso, Liza; Erlwein, Bobbie] Ctr Dis Control & Prevent, Div Publ Hlth Performance Improvement, Atlanta, GA 30329 USA.
[Monroe, Judith] Ctr Dis Control & Prevent, Off State Tribal Local & Terr, Atlanta, GA 30329 USA.
RP Thomas, CW (reprint author), Ctr Dis Control & Prevent, Off State Tribal Local & Terr Support, Century Ctr 1825, MS E70, Atlanta, GA 30329 USA.
EM CHT2@cdc.gov
NR 10
TC 5
Z9 5
U1 1
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
IS 1
BP 36
EP 38
DI 10.1097/PHH.0b013e3182a8a5cb
PG 3
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AG8TO
UT WOS:000335691300010
PM 24322684
ER
PT J
AU Wallace, H
Tilson, H
Carlson, VP
Valasek, T
AF Wallace, Harvey
Tilson, Hugh
Carlson, Valeria P.
Valasek, Tricia
TI Instrumental Roles of Governance in Accreditation: Responsibilities of
Public Health Governing Entities
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Article
C1 [Wallace, Harvey] No Michigan Univ, Coll Profess Studies, Marquette, MI 49855 USA.
[Tilson, Hugh] Univ N Carolina, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA.
[Carlson, Valeria P.] Ctr Dis Control & Prevent, Hlth Dept Syst Dev Branch, Div Publ Hlth Performance Improvement, Off State Tribal Local & Terr Support, Atlanta, GA USA.
[Valasek, Tricia] Univ Findlay, Findlay, OH USA.
[Valasek, Tricia] Natl Assoc Local Boards Hlth, Bowling Green, OH USA.
RP Wallace, H (reprint author), No Michigan Univ, Coll Profess Studies, Marquette, MI 49855 USA.
EM hwallace@nmu.edu
FU Intramural CDC HHS [CC999999]
NR 6
TC 3
Z9 3
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
IS 1
BP 61
EP 63
DI 10.1097/PHH.0b013e3182a45141
PG 3
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AG8TO
UT WOS:000335691300016
PM 24322689
ER
PT J
AU Thielen, L
Leff, M
Corso, L
Monteiro, E
Fisher, JS
Pearsol, J
AF Thielen, Lee
Leff, Marilyn
Corso, Liza
Monteiro, Erinn
Fisher, Jessica Solomon
Pearsol, Jim
TI A Study of Incentives to Support and Promote Public Health Accreditation
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Article
DE public health accreditation; incentives
AB Context: Accreditation of public health agencies through the Public Health Accreditation Board is voluntary. Incentives that encourage agencies to apply for accreditation have been suggested as important factors in facilitating participation by state and local agencies. Objective: The project describes both current and potential incentives that are available at the federal, state, and local levels. Design: Thirty-nine key informants from local, state, tribal, federal, and academic settings were interviewed from March through May 2012. Through open-ended interviews, respondents were asked about incentives that were currently in use in their settings and incentives they thought would help encourage participation in Public Health Accreditation Board accreditation. Results: Incentives currently in use by public health agencies based on interviews include (1) financial support, (2) legal mandates, (3) technical assistance, (4) peer support workgroups, and (5) state agencies serving as role models by seeking accreditation themselves. Key informants noted that state agencies are playing valuable and diverse roles in providing incentives for accreditation within their own states. Key informants also identified the Centers for Disease Control and Prevention and other players, such as private foundations, public health institutes, national and state associations, and academia as providing both technical and financial assistance to support accreditation efforts. Conclusions: State, tribal, local, and federal agencies, as well as related organizations can play an important role by providing incentives to move agencies toward accreditation.
C1 [Thielen, Lee; Leff, Marilyn] Thielen Consulting, Ft Collins, CO 80524 USA.
[Corso, Liza] Ctr Dis Control & Prevent, Off State Tribal Local & Terr Support, Div Publ Hlth Performance Improvement, Atlanta, GA USA.
[Monteiro, Erinn; Fisher, Jessica Solomon] Natl Assoc Cty & City Hlth Officials, Washington, DC USA.
[Pearsol, Jim] Assoc State & Terr Hlth Officials, Arlington, VA USA.
RP Thielen, L (reprint author), Thielen Consulting, 1308 Lindenwood Dr, Ft Collins, CO 80524 USA.
EM leethielen@aol.com
NR 11
TC 6
Z9 6
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
IS 1
BP 98
EP 103
DI 10.1097/PHH.0b013e31829ed746
PG 6
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AG8TO
UT WOS:000335691300029
PM 24322702
ER
PT J
AU Mercer, SL
Banks, SM
Verma, P
Fisher, JS
Corso, LC
Carlson, V
AF Mercer, Shawna L.
Banks, Starr M.
Verma, Pooja
Fisher, Jessica Solomon
Corso, Liza C.
Carlson, Valeria
TI Guiding the Way to Public Health Improvement: Exploring the Connections
Between The Community Guide's Evidence-Based Interventions and Health
Department Accreditation Standards
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Article
DE quality improvement; performance management; public health improvement;
public health systems; public health accreditation; evidence-based
public health
AB Context: Recent years have seen rising interest in initiatives that focus on public health improvement. This includes support for accreditation of public health departments-administered by the Public Health Accreditation Board (PHAB)-and increasing expectations that health departments should use evidence-based programs, services, and policies (interventions) such as those described in The Guide to Community Preventive Services (The Community Guide). Objective: This project was initiated to explore the potential connections between Community Guide interventions and PHAB domains, standards, and measures. Design: The project team focused on developing a Crosswalk tool to assist health departments in identifying evidence-based interventions from The Community Guide whose implementation could help document conformity with PHAB domains, standards, and measures. All Community Preventive Services Task Force-recommended interventions were reviewed to determine whether they reflect the intent and requirements of the PHAB standards and measures. Main Outcome Measures: Three types of connections were defined through which Community Guide interventions could be relevant to the required documentation for a PHAB measure. All instances of these connections were identified and included in the Crosswalk. Results: The Crosswalk tool consists of 2 tables. The first table cross-references individual PHAB domains, standards, and measures with interventions from The Community Guide that could help provide documentation for accreditation. The second table can help accreditation preparation staff to engage with program staff. It is searchable by Community Guide topic, identifying the PHAB measures that relate to each Community Guide intervention within that topic. The type, location, and extent of connections between Community Guide interventions and PHAB domains, standards, and measures are presented and discussed. Conclusions: Tools such as the Crosswalk can be instrumental in advancing the use of evidence-based interventions in public health practice.
C1 [Mercer, Shawna L.; Banks, Starr M.] Ctr Dis Control & Prevent, Community Guide Branch, Div Epidemiol Anal & Lib Serv Proposed, Ctr Surveillance Epidemiol & Lab Serv Proposed,Of, Atlanta, GA 30329 USA.
[Corso, Liza C.; Carlson, Valeria] Ctr Dis Control & Prevent, Div Publ Hlth Performance Improvement, Off State Tribal Local & Terr Support, Atlanta, GA 30329 USA.
[Verma, Pooja] Natl Assoc Cty & City Hlth Officials, Accreditat & Qual Improvement, Washington, DC USA.
[Fisher, Jessica Solomon] Natl Assoc Cty & City Hlth Officials, Publ Hlth Programs, Washington, DC USA.
RP Mercer, SL (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd NE,Mail Stop E-69, Atlanta, GA 30329 USA.
EM SMercer@cdc.gov
FU NCHM CDC HHS [HM08-805301SUPP10]
NR 12
TC 3
Z9 3
U1 2
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
IS 1
BP 104
EP 110
DI 10.1097/PHH.0b013e3182aa444c
PG 7
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AG8TO
UT WOS:000335691300030
PM 24322703
ER
PT J
AU Singleton, CM
Corso, L
Koester, D
Carlson, V
Bevc, CA
Davis, MV
AF Singleton, Christa-Marie
Corso, Liza
Koester, Deborah
Carlson, Valeria
Bevc, Christine A.
Davis, Mary V.
TI Accreditation and Emergency Preparedness: Linkages and Opportunities for
Leveraging the Connections
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Article
DE public health emergency preparedness; accreditation; public health
AB Background: Public health officials must frequently demonstrate the quality and value of public health services, especially during challenging fiscal climates. One of the ways that public health quality and accountability have been demonstrated is through the use of accreditation and standard setting initiatives. Objective: The objective of this analysis was to identify existing alignment opportunities between standards established by the Public Health Accreditation Board (PHAB) and the Centers for Disease Control and Prevention's (CDC's) public health preparedness (PHP) capabilities in order to optimize and leverage the connections for state and local public health professionals. Design: During March-May 2012, a PHAB/PHP crosswalk was developed by a research team from the CDC's Office for State, Tribal, Local and Territorial Support and Office of Public Health Preparedness and Response's Division of State and Local Readiness to examine the intersection of the PHP capabilities and the PHAB standards. The PHAB/PHP crosswalk used the CDC Public Health Preparedness Capabilities: National Standards for State and Local Planning (PHP Capabilities) and the PHAB Standards and Measures, Version 1.0 (PHAB Standards) as its source documents. To help illustrate the results of the crosswalk, alignment was also depicted through a network graph to transform the results into a visual depiction of the linkages between PHP capabilities and PHAB standards. Results: The most direct links to emergency preparedness were found in PHAB Domains 2 and 5. Opportunities for improved alignment were found throughout the standard documents, particularly in PHAB Domains 3, 8, and 11. The most direct links to accreditation were found in PHP capabilities 1, 2, 3, and 4. Conclusions: The results highlight the synergy between the infrastructure and foundational elements represented by accreditation and targeted programmatic activities supported by preparedness funding.
C1 [Singleton, Christa-Marie] Ctr Dis Control & Prevent, Div State & Local Readiness, Off Publ Hlth Preparedness & Response, Atlanta, GA 30333 USA.
[Corso, Liza] Ctr Dis Control & Prevent, Div Publ Hlth Performance Improvement, Off State Tribal Local & Terr Support, Atlanta, GA 30333 USA.
[Koester, Deborah] Carter Consulting Inc, Atlanta, GA USA.
[Koester, Deborah] Ctr Dis Control & Prevent, Off State Tribal Local & Terr Support, Atlanta, GA 30333 USA.
[Carlson, Valeria] Ctr Dis Control & Prevent, Dept Hlth, Off State Tribal Local & Terr Support, Atlanta, GA 30333 USA.
[Carlson, Valeria] Ctr Dis Control & Prevent, Syst Dev Branch, Div Publ Hlth Performance Improvement, Off State Tribal Local & Terr Support, Atlanta, GA 30333 USA.
[Bevc, Christine A.; Davis, Mary V.] UNC Gillings Sch Global Publ Hlth, North Carolina Inst Publ Hlth, Chapel Hill, NC USA.
RP Singleton, CM (reprint author), Ctr Dis Control & Prevent, Div State & Local Readiness, Off Publ Hlth Preparedness & Response, 600 Clifton Rd, Atlanta, GA 30333 USA.
EM zbi9@cdc.gov
FU OPHPR CDC HHS [1P01TP000296]
NR 18
TC 4
Z9 4
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
IS 1
BP 119
EP 124
DI 10.1097/PHH.0b013e3182a9dbd8
PG 6
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AG8TO
UT WOS:000335691300032
PM 24322705
ER
PT J
AU Koo, D
Miner, KR
Tilson, HH
Halverson, PK
AF Koo, Denise
Miner, Kathleen R.
Tilson, Hugh H.
Halverson, Paul K.
TI Workforce Standards as Part of Health Department Accreditation-Necessary
but Not Yet Sufficient
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Article
C1 [Koo, Denise] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
[Miner, Kathleen R.] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA.
[Tilson, Hugh H.] UNC Gillings Sch Global Publ Hlth, Chapel Hill, NC USA.
[Halverson, Paul K.] Indiana Univ, Richard M Fairbanks Sch Publ Hlth, Indianapolis, IN 46204 USA.
RP Koo, D (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd NE,Mailstop E-92, Atlanta, GA 30333 USA.
EM dkoo@cdc.gov
NR 5
TC 0
Z9 0
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
IS 1
BP 125
EP 127
DI 10.1097/PHH.0b013e3182a5a3a7
PG 3
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AG8TO
UT WOS:000335691300033
PM 24322706
ER
PT J
AU Daub, T
Doshi, S
Elligers, JJ
Pavletic, D
Pyron, T
AF Daub, Teresa
Doshi, Sonal
Elligers, Julia Joh
Pavletic, Denise
Pyron, Trina
TI Leveraging the Revised National Public Health Performance Standards
toMeet Today's Ever-Changing Public Health System Landscape
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Editorial Material
C1 [Daub, Teresa; Doshi, Sonal; Pyron, Trina] Ctr Dis Control & Prevent, Off State Tribal Local & Terr Support, Div Publ Hlth Performance Improvement, Atlanta, GA 30341 USA.
[Elligers, Julia Joh] Natl Assoc Cty & City Hlth Officials, Washington, DC USA.
[Pavletic, Denise] Assoc State & Terr Hlth Officials, Arlington, VA USA.
RP Daub, T (reprint author), Ctr Dis Control & Prevent, 4770 Buford Hwy NE,MS E-70, Atlanta, GA 30341 USA.
EM tdaub@cdc.gov
NR 10
TC 1
Z9 1
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
IS 1
BP 135
EP 137
DI 10.1097/PHH.0b013e3182a7bdae
PG 3
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AG8TO
UT WOS:000335691300035
PM 24322708
ER
PT J
AU Monroe, J
Collins, J
Ikeda, R
Khabbaz, R
AF Monroe, Judith
Collins, Janet
Ikeda, Robin
Khabbaz, Rima
TI Institutionalizing Public Health Department Accreditation Through CDC
Opportunities
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Editorial Material
ID PERFORMANCE
C1 [Monroe, Judith] Ctr Dis Control & Prevent, Off State Tribal Local & Terr Support, Atlanta, GA 30341 USA.
[Collins, Janet] Ctr Dis Control & Prevent, Div Nutr Phys Act & Obes, Atlanta, GA 30341 USA.
[Ikeda, Robin] Ctr Dis Control & Prevent, Off Noncommunicable Dis Injury & Environm Hlth, Atlanta, GA 30341 USA.
[Khabbaz, Rima] Ctr Dis Control & Prevent, Off Infect Dis, Atlanta, GA 30341 USA.
RP Monroe, J (reprint author), Ctr Dis Control & Prevent, Off State Tribal Local & Terr Support, 4770 Buford Hwy NE, Atlanta, GA 30341 USA.
EM JAMonroe@cdc.gov
NR 13
TC 0
Z9 0
U1 1
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
IS 1
BP 141
EP 144
DI 10.1097/PHH.0b013e3182a5a3c2
PG 4
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AG8TO
UT WOS:000335691300037
PM 24322710
ER
PT J
AU Cummings, PL
Kuo, T
Gase, LN
Mugavero, K
AF Cummings, Patricia L.
Kuo, Tony
Gase, Lauren N.
Mugavero, Kristy
TI Integrating Sodium Reduction Strategies in the Procurement Process and
Contracting of Food Venues in the County of Los Angeles Government,
2010-2012
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Article
DE County; healthy food procurement; program intervention; sodium limits
ID PHYSICAL-ACTIVITY; UNITED-STATES; HEALTH IMPACT; LOCAL-POLICY;
CONSUMPTION; OBESITY; CHOICE; MENU
AB Since sodium is ubiquitous in the food supply, recent approaches to sodium reduction have focused on increasing the availability of lower-sodium products through system-level and environmental changes. This article reviews integrated efforts by the Los Angeles County Sodium Reduction Initiative to implement these strategies at food venues in the County of Los Angeles government. The review used mixed methods, including a scan of the literature, key informant interviews, and lessons learned during 2010-2012 to assess program progress. Leveraging technical expertise and shared resources, the initiative strategically incorporated sodium reduction strategies into the overall work plan of a multipartnership food procurement program in Los Angeles County. To date, 3 County departments have incorporated new or updated nutrition requirements that included sodium limits and other strategies. The strategic coupling of sodium reduction to food procurement and general health promotion allowed for simultaneous advancement and acceleration of the County's sodium reduction agenda.
C1 [Cummings, Patricia L.; Kuo, Tony; Gase, Lauren N.] Los Angeles Cty Dept Publ Hlth, Los Angeles Cty Sodium Reduct Initiat, Div Chron Dis & Injury Prevent, Los Angeles, CA 90010 USA.
[Cummings, Patricia L.; Kuo, Tony; Gase, Lauren N.] Univ Calif Los Angeles, Los Angeles, CA USA.
[Mugavero, Kristy] Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, Atlanta, GA USA.
RP Cummings, PL (reprint author), Los Angeles Cty Dept Publ Hlth, Los Angeles Cty Sodium Reduct Initiat, Div Chron Dis & Injury Prevent, 3530 Wilshire Blvd,8th Floor, Los Angeles, CA 90010 USA.
EM pcummings@ph.lacounty.gov
FU Intramural CDC HHS [CC999999]; NCCDPHP CDC HHS [U50 DP003061, U58
DP003061]
NR 29
TC 3
Z9 4
U1 0
U2 7
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
SU 1
BP S16
EP S22
DI 10.1097/PHH.0b013e31829d7f63
PG 7
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AH2UU
UT WOS:000335977900004
PM 24322811
ER
PT J
AU Losby, JL
Patel, D
Schuldt, J
Hunt, GS
Stracuzzi, JC
Johnston, Y
AF Losby, Jan L.
Patel, Deesha
Schuldt, June
Hunt, Glynnis S.
Stracuzzi, Jeanne C.
Johnston, Yvonne
TI Sodium-Reduction Strategies for Meals Prepared for Older Adults
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Article
DE nutrition; older adults; sodium; sodium reduction
AB This article describes lessons learned from implementing sodium-reduction strategies in programs that provide meals to older adults in 2 New York counties, with one county replicating the approaches of the other. The implemented sodium-reduction strategies were product substitutions, recipe modifications, and cooking from scratch. Both counties were able to achieve modest sodium reductions in prepared meals. Lessons learned to implement sodium reduction strategies include the following: (1) identifying partners with shared experience and common goals; (2) engaging experts; (3) understanding the complexity of the meals system for older adults; (4) conducting sodium nutrient analysis; (5) making gradual and voluntary reductions to sodium content; and (6) working toward sustainable sodium reduction.
C1 [Losby, Jan L.; Patel, Deesha] Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, Atlanta, GA 30341 USA.
[Schuldt, June; Hunt, Glynnis S.] Schenectady Cty Publ Hlth Serv, Schenectady, NY USA.
[Stracuzzi, Jeanne C.] Broome Cty Off Aging, Binghamton, NY USA.
[Johnston, Yvonne] Binghamton Univ, Decker Sch Nursing, Binghamton, NY USA.
RP Losby, JL (reprint author), Ctr Dis Control & Prevent, 4770 Buford Hwy NE,Mailstop F-72, Atlanta, GA 30341 USA.
EM JLosby@cdc.gov
FU Intramural CDC HHS [CC999999]; NCCDPHP CDC HHS [U50 DP003064, U58
DP003064]
NR 12
TC 3
Z9 3
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
SU 1
BP S23
EP S30
DI 10.1097/PHH.0b013e3182a0e3ca
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AH2UU
UT WOS:000335977900005
PM 24322812
ER
PT J
AU Mugavero, KL
Gunn, JP
Dunet, DO
Bowman, BA
AF Mugavero, Kristy L.
Gunn, Janelle P.
Dunet, Diane O.
Bowman, Barbara A.
TI Sodium Reduction: An Important Public Health Strategy for Heart Health
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Editorial Material
ID UNITED-STATES; SCHOOL-DISTRICT; COUNTY; FOOD; ADULTS; CONSUMPTION;
POPULATION; CALIFORNIA; POLICY; MEALS
C1 [Mugavero, Kristy L.; Gunn, Janelle P.; Dunet, Diane O.; Bowman, Barbara A.] Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, Atlanta, GA 30341 USA.
RP Mugavero, KL (reprint author), Ctr Dis Control & Prevent, 4770 Buford Hwy,MS F72, Atlanta, GA 30341 USA.
EM frc9@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 30
TC 1
Z9 1
U1 2
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
SU 1
BP S1
EP S5
DI 10.1097/PHH.0b013e3182aa659c
PG 5
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AH2UU
UT WOS:000335977900001
PM 24322810
ER
PT J
AU Schuldt, J
Levings, JL
Kahn-Marshall, J
Hunt, G
Mugavero, K
Gunn, JP
AF Schuldt, June
Levings, Jessica Lee
Kahn-Marshall, Jennifer
Hunt, Glynnis
Mugavero, Kristy
Gunn, Janelle Peralez
TI Reducing Sodium Across the Board: A Pilot Program in Schenectady County
Independent Restaurants
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Article
DE independent restaurants; nutrition; sodium; sodium reduction
AB Excess sodium intake can lead to increased blood pressure. Restaurant foods contribute nearly a quarter of the sodium consumed in the American diet. The objective of the pilot project was to develop and implement in collaboration with independent restaurants a tool, the Restaurant Assessment Tool and Evaluation (RATE), to assess efforts to reduce sodium in independent restaurants and measure changes over time in food preparation categories, including menu, cooking techniques, and products. Twelve independent restaurants in Schenectady County, New York, voluntarily participated. From initial assessment to a 6-month follow-up assessment using the RATE, 11 restaurants showed improvement in the cooking category, 9 showed improvement in the menu category, and 7 showed improvement in the product category. Menu analysis conducted by the Schenectady County Health Department staff suggested that reported sodium-reduction strategies might have affected approximately 25% of the restaurant menu items. The findings from this project suggest that a facilitated assessment, such as the RATE, can provide a useful platform for independent restaurant owners and public health practitioners to discuss and encourage sodium reduction. The RATE also provides opportunities to build and strengthen relationships between public health care practitioners and independent restaurant owners, which may help sustain the positive changes made.
C1 [Schuldt, June; Hunt, Glynnis] Schenectady Cty Publ Hlth Serv, New York, NY USA.
[Kahn-Marshall, Jennifer] Cornell Cooperat Extens, New York, NY USA.
[Levings, Jessica Lee; Mugavero, Kristy; Gunn, Janelle Peralez] Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, Atlanta, GA 30341 USA.
RP Schuldt, J (reprint author), Ctr Dis Control & Prevent, Atlanta, GA 30341 USA.
EM frc9@cdc.gov
NR 7
TC 4
Z9 4
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
SU 1
BP S31
EP S37
DI 10.1097/PHH.0b013e31829d7b7c
PG 7
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AH2UU
UT WOS:000335977900006
PM 24322813
ER
PT J
AU Taylor, S
Tibbett, T
Patel, D
Bishop, E
AF Taylor, Stephanie
Tibbett, Theresa
Patel, Deesha
Bishop, Ereka
TI Use of Environmental Change Strategies to Facilitate Sodium Reduction: A
Case Study in a Rural California School District
SO JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
LA English
DT Article
DE environmental change; nutrition; rural school district; school meals;
sodium content; sodium reduction
ID BLOOD-PRESSURE; CHILDREN
AB Context: Excess sodium consumption increases the risk for hypertension, which is a leading risk factor for cardiovascular disease. For children and teenagers, school meals are a significant source of sodium consumption.
Objective: To describe the environmental change strategies that were implemented to reduce sodium in the school meals of a rural California school district.
Design: Descriptions of the environmental strategies, with an emphasis on staff training and infrastructure improvements.
Setting: School district of approximately two thousand 9th- to 12th-grade students in rural, northern California.
Participants: School administration and food service staff at the 5 high schools in Anderson Union High School District.
Intervention: Shasta County Public Health partnered with Anderson Union High School District to (1) facilitate changes to meal preparation practices, (2) improve cafeteria infrastructure, and (3) provide training and technical assistance to improve procurement strategies.
Results: Environmental strategies to reduce sodium in school meals were implemented in 2011. Anderson Union High School District has continued to successfully implement scratch cooking and improve procurement strategies to reduce sodium in school meals.
Conclusion: Using an approach that includes environmental change strategies can lead to sodium reduction in a school setting.
C1 [Taylor, Stephanie] Shasta Cty Hlth & Human Serv Agcy, Outcomes Planning & Evaluat Div, Redding, CA 96001 USA.
[Tibbett, Theresa; Bishop, Ereka] Shasta Cty Hlth & Human Serv Agcy, Hlth Commun Div, Publ Hlth Branch, Redding, CA 96001 USA.
[Patel, Deesha] Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, Atlanta, GA USA.
RP Taylor, S (reprint author), Shasta Cty Hlth & Human Serv Agcy, Redding, CA 96001 USA.
EM smtaylor@co.shasta.ca.us
FU Intramural CDC HHS [CC999999]; NCCDPHP CDC HHS [U50 DP003071, U58
DP003071]
NR 9
TC 4
Z9 4
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1078-4659
EI 1550-5022
J9 J PUBLIC HEALTH MAN
JI J. Public Health Manag. Pract.
PD JAN-FEB
PY 2014
VL 20
SU 1
BP S38
EP S42
DI 10.1097/PHH.0b013e31829d7726
PG 5
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AH2UU
UT WOS:000335977900007
PM 24322814
ER
PT J
AU Eaton, JW
Menzies, NA
Stover, J
Cambiano, V
Chindelevitch, L
Cori, A
Hontelez, JAC
Humair, S
Kerr, CC
Klein, DJ
Mishra, S
Mitchell, KM
Nichols, BE
Vickerman, P
Bakker, R
Barnighausen, T
Bershteyn, A
Bloom, DE
Boily, MC
Chang, ST
Cohen, T
Dodd, PJ
Fraser, C
Gopalappa, C
Lundgren, J
Martin, NK
Mikkelsen, E
Mountain, E
Pham, QD
Pickles, M
Phillips, A
Platt, L
Pretorius, C
Prudden, HJ
Salomon, JA
van de Vijver, DAMC
de Vlas, SJ
Wagner, BG
White, RG
Wilson, DP
Zhang, L
Blandford, J
Meyer-Rath, G
Remme, M
Revill, P
Sangrujee, N
Terris-Prestholt, F
Doherty, M
Shaffer, N
Easterbrook, PJ
Hirnschall, G
Hallett, TB
AF Eaton, Jeffrey W.
Menzies, Nicolas A.
Stover, John
Cambiano, Valentina
Chindelevitch, Leonid
Cori, Anne
Hontelez, Jan A. C.
Humair, Salal
Kerr, Cliff C.
Klein, Daniel J.
Mishra, Sharmistha
Mitchell, Kate M.
Nichols, Brooke E.
Vickerman, Peter
Bakker, Roel
Baernighausen, Till
Bershteyn, Anna
Bloom, David E.
Boily, Marie-Claude
Chang, Stewart T.
Cohen, Ted
Dodd, Peter J.
Fraser, Christophe
Gopalappa, Chaitra
Lundgren, Jens
Martin, Natasha K.
Mikkelsen, Evelinn
Mountain, Elisa
Pham, Quang D.
Pickles, Michael
Phillips, Andrew
Platt, Lucy
Pretorius, Carel
Prudden, Holly J.
Salomon, Joshua A.
van de Vijver, David A. M. C.
de Vlas, Sake J.
Wagner, Bradley G.
White, Richard G.
Wilson, David P.
Zhang, Lei
Blandford, John
Meyer-Rath, Gesine
Remme, Michelle
Revill, Paul
Sangrujee, Nalinee
Terris-Prestholt, Fern
Doherty, Meg
Shaffer, Nathan
Easterbrook, Philippa J.
Hirnschall, Gottfried
Hallett, Timothy B.
TI Health benefits, costs, and cost-effectiveness of earlier eligibility
for adult antiretroviral therapy and expanded treatment coverage: a
combined analysis of 12 mathematical models
SO LANCET GLOBAL HEALTH
LA English
DT Article
ID HIV PREVENTION; SOUTH-AFRICA; IMPACT; RISK; SEX; ART; PREVALENCE;
INFECTION; SETTINGS; HIV/AIDS
AB Background New WHO guidelines recommend initiation of antiretroviral therapy for HIV-positive adults with CD4 counts of 500 cells per mu L or less, a higher threshold than was previously recommended. Country decision makers have to decide whether to further expand eligibility for antiretroviral therapy accordingly. We aimed to assess the potential health benefits, costs, and cost-effectiveness of various eligibility criteria for adult antiretroviral therapy and expanded treatment coverage.
Methods We used several independent mathematical models in four settings-South Africa (generalised epidemic, moderate antiretroviral therapy coverage), Zambia (generalised epidemic, high antiretroviral therapy coverage), India (concentrated epidemic, moderate antiretroviral therapy coverage), and Vietnam (concentrated epidemic, low antiretroviral therapy coverage)-to assess the potential health benefits, costs, and cost-effectiveness of various eligibility criteria for adult antiretroviral therapy under scenarios of existing and expanded treatment coverage, with results projected over 20 years. Analyses assessed the extension of eligibility to include individuals with CD4 counts of 500 cells per mu L or less, or all HIV-positive adults, compared with the previous (2010) recommendation of initiation with CD4 counts of 350 cells per mu L or less. We assessed costs from a health-system perspective, and calculated the incremental cost (in US$) per disability-adjusted life-year (DALY) averted to compare competing strategies. Strategies were regarded very cost effective if the cost per DALY averted was less than the country's 2012 per-head gross domestic product (GDP; South Africa: $8040; Zambia: $1425; India: $1489; Vietnam: $1407) and cost effective if the cost per DALY averted was less than three times the per-head GDP.
Findings In South Africa, the cost per DALY averted of extending eligibility for antiretroviral therapy to adult patients with CD4 counts of 500 cells per mu L or less ranged from $237 to $1691 per DALY averted compared with 2010 guidelines. In Zambia, expansion of eligibility to adults with a CD4 count threshold of 500 cells per mu L ranged from improving health outcomes while reducing costs (ie, dominating the previous guidelines) to $749 per DALY averted. In both countries results were similar for expansion of eligibility to all HIV-positive adults, and when substantially expanded treatment coverage was assumed. Expansion of treatment coverage in the general population was also cost effective. In India, the cost for extending eligibility to all HIV-positive adults ranged from $131 to $241 per DALY averted, and in Vietnam extending eligibility to patients with CD4 counts of 500 cells per mu L or less cost $290 per DALY averted. In concentrated epidemics, expanded access for key populations was also cost effective.
Interpretation Our estimates suggest that earlier eligibility for antiretroviral therapy is very cost effective in low-income and middle-income settings, although these estimates should be revisited when more data become available. Scaling up antiretroviral therapy through earlier eligibility and expanded coverage should be considered alongside other high-priority health interventions competing for health budgets.
C1 [Cori, Anne; Fraser, Christophe] Univ London Imperial Coll Sci Technol & Med, MRC Ctr Outbreak Anal & Modelling, London W2 1PG, England.
[Eaton, Jeffrey W.; Mishra, Sharmistha; Boily, Marie-Claude; Mountain, Elisa; Pickles, Michael; Hallett, Timothy B.] Univ London Imperial Coll Sci Technol & Med, Dept Infect Dis Epidemiol, London W2 1PG, England.
[Menzies, Nicolas A.; Salomon, Joshua A.] Harvard Univ, Sch Publ Hlth, Ctr Hlth Decis Sci, Boston, MA 02115 USA.
[Chindelevitch, Leonid; Humair, Salal; Baernighausen, Till; Bloom, David E.; Salomon, Joshua A.] Harvard Univ, Sch Publ Hlth, Dept Global Hlth & Populat, Boston, MA 02115 USA.
[Cohen, Ted] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.
[Stover, John; Gopalappa, Chaitra; Pretorius, Carel] Futures Inst, Glastonbury, CT USA.
[Cambiano, Valentina; Phillips, Andrew] UCL, Res Dept Infect & Populat Hlth, London, England.
[Hontelez, Jan A. C.; Bakker, Roel; de Vlas, Sake J.] Univ Med Ctr Rotterdam, Erasmus MC, Dept Publ Hlth, Rotterdam, Netherlands.
[Nichols, Brooke E.; van de Vijver, David A. M. C.] Univ Med Ctr Rotterdam, Erasmus MC, Dept Virol, Rotterdam, Netherlands.
[Hontelez, Jan A. C.; Baernighausen, Till] Univ KwaZulu Natal, Africa Ctr Hlth & Populat Studies, Mtubatuba, South Africa.
[Hontelez, Jan A. C.; Mikkelsen, Evelinn] Radboud Univ Nijmegen, Med Ctr, Dept Primary & Community Care, Nijmegen Int Ctr Hlth Syst Anal & Educ NICHE, NL-6525 ED Nijmegen, Netherlands.
[Kerr, Cliff C.; Pham, Quang D.; Wilson, David P.; Zhang, Lei] Univ New S Wales, Kirby Inst, Sydney, NSW, Australia.
[Klein, Daniel J.; Bershteyn, Anna; Chang, Stewart T.; Wagner, Bradley G.] Inst Dis Modelling, Intellectual Ventures Lab, Bellevue, WA USA.
[Mishra, Sharmistha] Univ Toronto, St Michaels Hosp, Div Infect Dis, Toronto, ON, Canada.
[Mitchell, Kate M.; Vickerman, Peter; Martin, Natasha K.; Platt, Lucy; Prudden, Holly J.; Remme, Michelle; Terris-Prestholt, Fern] London Sch Hyg & Trop Med, Social & Math Epidemiol Grp, London WC1, England.
[Dodd, Peter J.; White, Richard G.] London Sch Hyg & Trop Med, Dept Infect Dis Epidemiol, London WC1, England.
[Cohen, Ted] Brigham & Womens Hosp, Div Global Hlth Equ, Boston, MA 02115 USA.
[Lundgren, Jens] Copenhagen Univ Hosp, Rigshosp, Ctr Viral Dis, Dept Infect Dis, Copenhagen, Denmark.
[Lundgren, Jens] Univ Copenhagen, Fac Hlth Sci, Copenhagen, Denmark.
[Martin, Natasha K.] Univ Bristol, Sch Social & Community Med, Bristol, Avon, England.
[Blandford, John; Sangrujee, Nalinee] US Ctr Dis Control & Prevent, Div Global HIV AIDS, Atlanta, GA USA.
[Meyer-Rath, Gesine] Boston Univ, Ctr Global Hlth & Dev, Boston, MA 02215 USA.
[Meyer-Rath, Gesine] Univ Witwatersrand, Dept Med, Hlth Econ & Epidemiol Res Off, Fac Hlth Sci, ZA-2001 Johannesburg, South Africa.
[Revill, Paul] Univ York, Ctr Hlth Econ, York YO10 5DD, N Yorkshire, England.
[Doherty, Meg; Shaffer, Nathan; Easterbrook, Philippa J.; Hirnschall, Gottfried] WHO, Dept HIV AIDS, CH-1211 Geneva, Switzerland.
RP Hallett, TB (reprint author), Univ London Imperial Coll Sci Technol & Med, Dept Infect Dis Epidemiol, London W2 1PG, England.
EM timothy.hallett@imperial.ac.uk
RI Phillips, Andrew/B-4427-2008; White, Richard/D-5407-2009; Fraser,
Christophe/A-8109-2008; Salomon, Joshua/D-3898-2009;
OI Pickles, Michael/0000-0002-6754-3945; Mishra,
Sharmistha/0000-0001-8492-5470; Eaton, Jeffrey/0000-0001-7728-728X;
Phillips, Andrew/0000-0003-2384-4807; White,
Richard/0000-0003-4410-6635; Fraser, Christophe/0000-0003-2399-9657;
Salomon, Joshua/0000-0003-3929-5515; Gopalappa,
Chaitra/0000-0001-8384-6041; Lundgren, Jens/0000-0001-8901-7850; Dodd,
Pete/0000-0001-5825-9347
FU Bill & Melinda Gates Foundation; WHO; Bill and Melinda Gates through the
Global Good Fund; Canadian Foundation for AIDS (CANFAR) [023-015];
Wellcome Trust [086431/Z/08/Z]; US National Institute of General Medical
Sciences [U54GM088558]; World Bank; Australian Research Council;
University of New South Wales; AusAID; UK Medical Research Council
[G0802414, MR/J005088/1]; Bill & Melinda Gates Foundation (Consortium to
Respond Effectively to the AIDS/TB Epidemic) [19790.01]; Bill & Melinda
Gates Foundation (TB Modelling and Analysis Consortium) [21675]; Aids
Fonds in Amsterdam, Netherlands [2010-035]; European Union FP7 CHAIN
grant [223131]; UK National Institute for Health Research postdoctoral
fellowship; UNAIDS India
FX The study was funded by the Bill & Melinda Gates Foundation and WHO. We
thank Ellen McRobie and Annick Borquez from Imperial College London
(London, UK) for coordinating the HIV Modelling Consortium ART
Eligibility Guidelines modelling project. We thank Mary Mahy from UNAIDS
(Geneva, Switzerland) for providing additional information about UNAIDS'
country-level epidemiological estimates. We thank Emmanuela Gakidou and
Herbert Duber from the Institute for Health Metrics and Evaluation at
the University of Washington (Seattle, WA, USA) for providing
information about antiretroviral therapy programmes in South Africa and
Zambia. We thank Elliot Raizes from the US Centers for Disease Control
and Prevention (CDC, Atlanta, GA, USA) for input on supply-chain
management costs for antiretroviral drugs. We thank the Clinton Health
Access Initiative (New York, NY, USA) and the Division of Global
HIV/AIDS of the CDC for access to unpublished cost estimates. VC and AP
acknowledge the University College London Research Computing Services
(Legion Cluster; London, UK) and input to the synthesis model from
Deborah Ford, Alec Miners, Paul Revill, Fumiyo Nakagawa, and Deenan
Pillay. DJK, AB, STC, and BGW thank Bill and Melinda Gates for their
active support of this work and their sponsorship through the Global
Good Fund. M-CB, SM, EMo, and MP thank all other members of the
Strategic Epi-ART in India Modeling team for their contribution to data
and model inputs. M-CB, SM, EMo, and MP acknowledge the Canadian
Foundation for AIDS (CANFAR, research grant number 023-015) for funding
the Belgaum modelling. KMM and HJP acknowledge funding from the Wellcome
Trust (086431/Z/08/Z). TC received funding from the US National
Institute of General Medical Sciences (U54GM088558; the content is
solely the responsibility of the authors and does not necessarily
represent the official views of the National Institute of General
Medical Sciences or the National Institutes of Health). DPW, CCK, QDP,
and LZ acknowledge funding from the World Bank, Australian Research
Council, University of New South Wales, and AusAID. QDP acknowledges
scholarship support from AusAID. RGW acknowledges research funding from
the UK Medical Research Council (Methodology Research Fellowship
G0802414 and grant MR/J005088/1) and the Bill & Melinda Gates Foundation
(Consortium to Respond Effectively to the AIDS/TB Epidemic [19790.01]
and TB Modelling and Analysis Consortium [21675]). BEN and DAMCvdV
acknowledge research funding from the Aids Fonds (grant 2010-035) in
Amsterdam, Netherlands, and the European Union FP7 CHAIN grant (223131).
NKM acknowledges funding from a UK National Institute for Health
Research postdoctoral fellowship. PV acknowledges funding support from
UNAIDS India for modelling work in northeast India. The findings and
conclusions in this report are those of the authors and do not
necessarily represent the official positions of the CDC or WHO.
NR 49
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U1 5
U2 20
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 2214-109X
J9 LANCET GLOB HEALTH
JI Lancet Glob. Health
PD JAN
PY 2014
VL 2
IS 1
BP E23
EP E34
DI 10.1016/S2214-109X(13)70172-4
PG 12
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AH8YK
UT WOS:000336423900015
PM 25104632
ER
PT J
AU Dunne, EF
Flagg, EW
Unger, ER
Hsu, K
Ghanen, K
Kerndt, P
Shlay, JC
Koutsky, LA
Datta, DS
Panicker, G
Zaidi, A
Weinstock, H
Markowitz, LE
AF Dunne, Eileen F.
Flagg, Elaine W.
Unger, Elizabeth R.
Hsu, Kathy
Ghanen, Khalil
Kerndt, Peter
Shlay, Judy C.
Koutsky, Laura A.
Datta, Deblina S.
Panicker, Gitika
Zaidi, Akbar
Weinstock, Hillard
Markowitz, Lauri E.
TI Would Young Women Attending Sexually Transmitted Disease Clinics Benefit
From Human Papillomavirus Vaccination? An Assessment of Human
Papillomavirus DNA and Seropositivity From Human Papillomavirus Sentinel
Surveillance, 2003Y2005
SO SEXUALLY TRANSMITTED DISEASES
LA English
DT Article
ID HPV INFECTION; EFFICACY; STATES
AB Background There are limited data on the proportion who have been exposed to vaccine-type human papillomavirus (HPV) among women attending sexually transmitted disease (STD) clinics; this information could inform the potential benefits of HPV vaccination for women attending this venue.
Methods Human papillomavirus surveillance was conducted in STD clinics in Baltimore, MD; Boston, MA; Denver, CO; Los Angeles, CA; and Seattle, WA, among women receiving cervical cancer screening from January 2003 to December 2005. The women had specimens collected for cervical cytology HPV testing by L1 consensus polymerase chain reaction testing and serologic assessment for HPV 6, 11, 16, and 18 using the competitive Luminex immunoassay. Results from 880 women with adequate specimens were included. Women were HPV naive if they were both HPV DNA negative and seronegative for a specific HPV type.
Results One hundred seventy women (19.3%) had HPV 16, 18, 6, or 11 DNA, and 418 (47.5%) were HPV 16, 18, 6, or 11 seropositive. Four hundred ten (46.6%) women were naive to all 4 types, 570 (64.8%) were naive to both HPV 16 and 18, and 545 (61.9%) were naive to both HPV 6 and 11. Almost all (99.3%) women were naive to at least 1 vaccine HPV type.
Conclusions Almost half of young women age eligible for HPV vaccine and attending STD clinics were naive to all 4 HPV types, and more than half were naive to both HPV 16 and 18. This assessment suggests that most young women attending this venue might benefit from HPV vaccination.
C1 [Dunne, Eileen F.; Flagg, Elaine W.; Unger, Elizabeth R.; Datta, Deblina S.; Panicker, Gitika; Zaidi, Akbar; Weinstock, Hillard; Markowitz, Lauri E.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Hsu, Kathy] Massachusetts Dept Publ Hlth, Div STD Prevent, Boston, MA USA.
[Ghanen, Khalil] Johns Hopkins Univ, Sch Med, Baltimore, MD USA.
[Kerndt, Peter] Cty Los Angeles Dept Hlth Serv, STD Program, Los Angeles, CA USA.
[Shlay, Judy C.] Denver Publ Hlth, Denver, CO USA.
[Koutsky, Laura A.] Univ Washington, Seattle, WA 98195 USA.
[Datta, Deblina S.] GAVI, Geneva, Switzerland.
RP Dunne, EF (reprint author), CDC, Div STD Prevent, 1600 Clifton Rd,MS E-02, Atlanta, GA 30333 USA.
EM Dde9@cdc.gov
NR 14
TC 1
Z9 1
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0148-5717
EI 1537-4521
J9 SEX TRANSM DIS
JI Sex. Transm. Dis.
PD JAN
PY 2014
VL 41
IS 1
BP 46
EP 49
DI 10.1097/OLQ.0000000000000071
PG 4
WC Infectious Diseases
SC Infectious Diseases
GA AH5YQ
UT WOS:000336207800009
PM 24326582
ER
PT J
AU Anschuetz, G
Asbel, L
Salmon, ME
Johnson, CC
AF Anschuetz, Greta
Asbel, Lenore
Salmon, Melinda E.
Johnson, Caroline C.
TI Use of First- Line Treatment for Neisseria gonorrhoeae After Treatment
Guideline Changes
SO SEXUALLY TRANSMITTED DISEASES
LA English
DT Article
ID THREAT
AB After 2 notices with treatment recommendation changes for Neisseria gonorrhoeae, the Philadelphia Department of Public Health documented medical therapy for 92% (3279/3551) of cases; 3001 (92%) received a recommended therapy. Nonrecommended therapies were documented in 8% of cases. Providers diagnosing 2 or less N. gonorrhoeae cases were more likely to use nonrecommended therapy.
C1 [Anschuetz, Greta; Asbel, Lenore; Salmon, Melinda E.; Johnson, Caroline C.] Philadelphia Dept Publ Hlth, Div Dis Control, Philadelphia, PA 19146 USA.
[Salmon, Melinda E.] US Ctr Dis Control & Prevent, Div STD Prevent, Atlanta, GA USA.
RP Anschuetz, G (reprint author), Philadelphia Dept Publ Hlth, 500 S Broad St, Philadelphia, PA 19146 USA.
EM Greta.Anschuetz@phila.gov
FU Comprehensive STD Prevention Systems Projects grant
FX Funding for this analysis was made possible by funding from
Comprehensive STD Prevention Systems Projects grant.
NR 8
TC 5
Z9 5
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0148-5717
EI 1537-4521
J9 SEX TRANSM DIS
JI Sex. Transm. Dis.
PD JAN
PY 2014
VL 41
IS 1
BP 64
EP 66
DI 10.1097/OLQ.0000000000000061
PG 3
WC Infectious Diseases
SC Infectious Diseases
GA AH5YQ
UT WOS:000336207800013
PM 24335745
ER
PT J
AU Haderxhanaj, LT
Gift, TL
Loosier, PS
Cramer, RC
Leichliter, JS
AF Haderxhanaj, Laura T.
Gift, Thomas L.
Loosier, Penny S.
Cramer, Ryan C.
Leichliter, Jami S.
TI Trends in Receipt of Sexually Transmitted Disease Services Among Women
15 to 44 Years Old in the United States, 2002 to 2006Y2010
SO SEXUALLY TRANSMITTED DISEASES
LA English
DT Article
ID CHLAMYDIA
AB Background To describe recent trends in the receipt of sexually transmitted disease (STD) services among women (age, 15-44 years) from 2002 to 2006-2010 using the National Survey of Family Growth.
Methods We analyzed trends in demographics, health insurance, and visit-related variables of women reporting receipt of STD services (counseling, testing, or treatment) in the past 12 months. We also analyzed trends in the source of STD services and the payment method used.
Results Receipt of STD services reported by women in the past 12 months increased from 2002 (12.6%) to 2006-2010 (16.0%; P < 0.001). Receipt of services did not increase among adolescents (P = 0.592). Among women receiving STD services from a private doctor/HMO, the percentage with private insurance decreased over time (74.6%-66.8%), whereas the percentage with Medicaid increased (12.8%-19.7%; P = 0.020). For women receiving STD services at a public clinic or nonprimary care facility, there were no statistically significant differences by demographics, except that fewer adolescents but more young adults reported using a public clinic over time (P = 0.038). Among women who reported using Medicaid as payment, receipt of STD services at a public clinic significantly decreased (36.8%-25.4%; P = 0.019). For women who paid for STD services with private insurance, the only significant difference was an increase in having a copay over time (61.3%-70.1%; P = 0.012).
Conclusions Despite a significant increase in receipt of STD services over time, many women at risk for STDs did not receive services including adolescents. In addition, we identified important shifts in payment methods during this time frame.
C1 [Haderxhanaj, Laura T.; Gift, Thomas L.; Loosier, Penny S.; Cramer, Ryan C.; Leichliter, Jami S.] Ctr Dis Control & Prevent, Div STD Prevent, Atlanta, GA 30333 USA.
RP Haderxhanaj, LT (reprint author), Ctr Dis Control & Prevent, Div STD Prevent, 1600 Clifton Rd,Mailstop E-02, Atlanta, GA 30333 USA.
EM LHaderxhanaj@cdc.gov
FU US Department of Energy; CDC
FX This research was supported, in part, by an appointment to the Research
Participation Program at the Centers for Disease Control and Prevention
(CDC) administered by the Oak Ridge Institute for Science and Education
through an interagency agreement between the US Department of Energy and
CDC.
NR 26
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Z9 6
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0148-5717
EI 1537-4521
J9 SEX TRANSM DIS
JI Sex. Transm. Dis.
PD JAN
PY 2014
VL 41
IS 1
BP 67
EP 73
DI 10.1097/OLQ.0000000000000058
PG 7
WC Infectious Diseases
SC Infectious Diseases
GA AH5YQ
UT WOS:000336207800014
PM 24335746
ER
PT J
AU Rukh, S
Khurana, R
Mickey, T
Anderson, L
Velasquez, C
Taylor, M
AF Rukh, Sana
Khurana, Renuka
Mickey, Tom
Anderson, Larissa
Velasquez, Corinne
Taylor, Melanie
TI Chlamydia and Gonorrhea Diagnosis, Treatment, Personnel Cost Savings,
and Service Delivery Improvements After the Implementation of Express
Sexually Transmitted Disease Testing in Maricopa County, Arizona
SO SEXUALLY TRANSMITTED DISEASES
LA English
DT Article
ID VISIT OPTION; INFECTIONS; EFFICIENCY; CLINICS
AB Background The demand for low-cost sexually transmitted disease (STD) services in Maricopa County (Phoenix area) is high. Improved methods for STD/HIV testing are needed to increase the number of patients receiving testing.
Objectives The present study sought to evaluate an STD/HIV express testing (ET) option for patients identified as being at lower risk for infection.
Methods Clients reporting current STD symptoms, contact to an infected partner, or health department referral were identified via questionnaire and routed to a traditional provider visit (PV); those not reporting these situations were routed to ET (laboratory-only). Demographics, treatment completion, and treatment intervals were compared among patients diagnosed as having chlamydia and gonorrhea through ET and PV encounters in September 2008 to July 2011. Personnel costs were compared for each of the 2 visit types. The number of clinic turn-aways for the 2-month time interval before the start of the program was compared with the 2-month interval at the end of the evaluation.
Results Of the 36,946 clients seen at Maricopa County Department of Public Health, 7466 (20.2%) were patients seen through express visits. Overall chlamydia and gonorrhea positivity was lower among ET patients (527/7466; 7.1%) as compared with those tested through PVs (6323/29,480; 21.4%). Treatment completion rates were comparable but were higher among patients seen through PVs (99%) as compared with ET (94%). A savings of $2936 per 1000 patients seen was achieved when 20% of clients were routed through ET. Clinic turn-aways decreased significantly, from 159 clients during the 2 months before implementation of ET to 6 patients during the last 2 months of evaluation (96% reduction).
Conclusions This ET system included an effective patient routing process that provided an efficient way to increase access to STD testing among persons at lower risk, at a reduced cost per patient, while maintaining high treatment coverage.
C1 [Rukh, Sana] Univ Arizona, Mel & Enid Zuckerman Coll Publ Hlth, Phoenix, AZ 85004 USA.
[Khurana, Renuka; Mickey, Tom; Velasquez, Corinne; Taylor, Melanie] Maricopa Cty Dept Publ Hlth, Phoenix, AZ USA.
[Anderson, Larissa; Taylor, Melanie] Arizona Dept Hlth Serv, Phoenix, AZ 85007 USA.
[Taylor, Melanie] Ctr Dis Control & Prevent, Div STD Prevent, Atlanta, GA USA.
RP Rukh, S (reprint author), Univ Arizona, Mel & Enid Zuckerman Coll Publ Hlth, 550 East Van Buren St, Phoenix, AZ 85004 USA.
EM srukh@email.arizona.edu
NR 13
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Z9 6
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0148-5717
EI 1537-4521
J9 SEX TRANSM DIS
JI Sex. Transm. Dis.
PD JAN
PY 2014
VL 41
IS 1
BP 74
EP 78
DI 10.1097/OLQ.0000000000000070
PG 5
WC Infectious Diseases
SC Infectious Diseases
GA AH5YQ
UT WOS:000336207800015
PM 24326585
ER
PT J
AU Chiu, CH
Vagi, SJ
Wolkin, AF
Martin, JP
Noe, RS
AF Chiu, Cindy H.
Vagi, Sara J.
Wolkin, Amy F.
Martin, John Paul
Noe, Rebecca S.
TI Evaluation of the National Weather Service Extreme Cold Warning
Experiment in North Dakota
SO WEATHER CLIMATE AND SOCIETY
LA English
DT Article
DE Emergency preparedness; Field experiments; Planning; Societal impacts;
Windchill
AB Dangerously cold weather threatens life and property. During periods of extreme cold due to wind chill, the National Weather Service (NWS) issues wind chill warnings to prompt the public to take action to mitigate risks. Wind chill warnings are based on ambient temperatures and wind speeds. Since 2010, NWS has piloted a new extreme cold warning issued for cold temperatures in wind and nonwind conditions. The North Dakota Department of Health, NWS, and the Centers for Disease Control and Prevention collaborated in conducting household surveys in Burleigh County, North Dakota, to evaluate this new warning. The objectives of the evaluation were to assess whether residents heard the new warning and to determine if protective behaviors were prompted by the warning. This was a cross-sectional survey design using the Community Assessment for Public Health Emergency Response (CASPER) methodology to select a statistically representative sample of households from Burleigh County. From 10 to 11 April 2012, 188 door-to-door household interviews were completed. The CASPER methodology uses probability sampling with weighted analysis to estimate the number and percentage of households with a specific response within Burleigh County. The majority of households reported having heard both the extreme cold and wind chill warnings, and both warnings prompted protective behaviors. These results suggest this community heard the new warning and took protective actions after hearing the warning.
C1 [Chiu, Cindy H.; Vagi, Sara J.; Wolkin, Amy F.; Noe, Rebecca S.] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Atlanta, GA USA.
[Martin, John Paul] NOAA, Natl Weather Serv, Weather Forecast Off, Bismarck, ND USA.
RP Noe, RS (reprint author), CDC, Natl Ctr Environm Hlth, 4770 Buford Hwy,MS F-60, Atlanta, GA 30341 USA.
EM rhn9@cdc.gov
OI Chiu, Cindy H/0000-0003-2226-2776
FU Intramural CDC HHS [CC999999]
NR 19
TC 0
Z9 0
U1 1
U2 6
PU AMER METEOROLOGICAL SOC
PI BOSTON
PA 45 BEACON ST, BOSTON, MA 02108-3693 USA
SN 1948-8327
EI 1948-8335
J9 WEATHER CLIM SOC
JI Weather Clim. Soc.
PD JAN
PY 2014
VL 6
IS 1
BP 22
EP 31
DI 10.1175/WCAS-D-13-00023.1
PG 10
WC Environmental Studies; Meteorology & Atmospheric Sciences
SC Environmental Sciences & Ecology; Meteorology & Atmospheric Sciences
GA AG8CJ
UT WOS:000335646000003
PM 27239260
ER
PT J
AU Li, CY
Wen, XJ
Pavkov, ME
Zhao, GX
Balluz, LS
Ford, ES
Williams, D
Gotway, CA
AF Li, Chaoyang
Wen, Xiao-Jun
Pavkov, Meda E.
Zhao, Guixiang
Balluz, Lina S.
Ford, Earl S.
Williams, Desmond
Gotway, Carol A.
TI Awareness of Kidney Disease among US Adults: Findings from the 2011
Behavioral Risk Factor Surveillance System
SO AMERICAN JOURNAL OF NEPHROLOGY
LA English
DT Article
DE Kidney disease; Prevalence; Awareness; Hypertension; Diabetes
ID HEALTH INTERVIEW SURVEY; NATIONAL-HEALTH; RENAL-DISEASE; UNITED-STATES;
PREVALENCE; POPULATION; MORTALITY; TRENDS
AB Background: The prevalence of chronic kidney disease as measured by biomarkers is increasing, but the recognition for this condition remains low in the USA. Little is known about the awareness of kidney disease at the state level.
Methods: Data from 490,302 adults aged 18 years or older in all 50 states as well as the District of Columbia who participated in the 2011 Behavioral Risk Factor Surveillance System were analyzed. Kidney disease diagnosis, a measure of individual awareness, was ascertained by participants' self-report in the telephone survey. Prevalence ratios of self-reported kidney disease in sub-populations were estimated and tested using log-linear regression analyses with a robust variance estimator.
Results: The unadjusted prevalence of self-reported kidney disease was estimated to be 2.5%. After adjustment for age and all other selected covariates, Hispanics had a higher prevalence than non-Hispanic whites (adjusted prevalence ratio 1.2, 95% CI 1.0-1.4). Persons who were unemployed (adjusted prevalence ratio 1.4, 95% CI 1.2-1.5) had a higher prevalence than those who were employed. Persons who had hypertension (adjusted prevalence ratio 1.9, 95% CI 1.7-2.1), diabetes (adjusted prevalence ratio 1.7,95% CI 1.5-1.8), cardiovascular disease (coronary heart disease, myocardial infarction or stroke; adjusted prevalence ratio 1.5, 95% CI 1.4-1.6) or cancer (adjusted prevalence ratio 1.5,95% CI 1.3-1.6) had a higher prevalence of self-reported kidney disease than those without these conditions.
Conclusion:The overall awareness of kidney disease was low in the general population. Efforts are needed to promote the awareness and early detection of kidney disease in public health services and clinical practice. (C) 2014 S. Karger AG, Basel
C1 [Li, Chaoyang; Wen, Xiao-Jun; Balluz, Lina S.] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Div Environm Hazards & Hlth Effects, Atlanta, GA 30341 USA.
[Pavkov, Meda E.; Williams, Desmond] Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Div Diabet Translat, Atlanta, GA 30341 USA.
[Zhao, Guixiang; Ford, Earl S.; Gotway, Carol A.] Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Div Populat Hlth, Atlanta, GA 30341 USA.
RP Li, CY (reprint author), Ctr Dis Control & Prevent, 4770 Buford Highway,MS F60, Atlanta, GA 30341 USA.
EM cli@cdc.gov
NR 22
TC 5
Z9 6
U1 0
U2 2
PU KARGER
PI BASEL
PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND
SN 0250-8095
EI 1421-9670
J9 AM J NEPHROL
JI Am. J. Nephrol.
PY 2014
VL 39
IS 4
BP 306
EP 313
DI 10.1159/000360184
PG 8
WC Urology & Nephrology
SC Urology & Nephrology
GA AH3HG
UT WOS:000336013700004
PM 24732234
ER
PT J
AU Biggerstaff, M
Jhung, MA
Reed, C
Garg, S
Balluz, L
Fry, AM
Finelli, L
AF Biggerstaff, M.
Jhung, M. A.
Reed, C.
Garg, S.
Balluz, L.
Fry, A. M.
Finelli, L.
TI Impact of medical and behavioural factors on influenza-like illness,
healthcare-seeking, and antiviral treatment during the 2009 H1N1
pandemic: USA, 2009-2010
SO EPIDEMIOLOGY AND INFECTION
LA English
DT Article
DE Healthcare-seeking behaviour; influenza; influenza A(H1N1)pdm09;
influenza antiviral treatment
ID RESPIRATORY-TRACT COMPLICATIONS; FACTOR SURVEILLANCE SYSTEM;
CIGARETTE-SMOKING; UNITED-STATES; RISK-FACTOR; EPIDEMIC INFLUENZA;
VACCINATION; PREVALENCE; CHILDREN; EFFICACY
AB We analysed a cross-sectional telephone survey of U.S. adults to assess the impact of selected characteristics on healthcare-seeking behaviours and treatment practices of people with influenza-like illness (ILI) from September 2009 to March 2010. Of 216431 respondents, 81% reported ILI. After adjusting for selected characteristics, respondents aged 18-64 years with the following factors were more likely to report ILI: a diagnosis of asthma [adjusted odds ratio (aOR) 188, 95% CI 167-213] or heart disease (aOR 141, 95% CI 117-170), being disabled (aOR 175, 95% CI 157-196), and reporting financial barriers to healthcare access (aOR 163, 95% CI 145-182). Similar associations were seen in respondents aged 65 years. Forty percent of respondents with ILI sought healthcare, and 14% who sought healthcare reported receiving influenza antiviral treatment. Treatment was not more frequent in patients with high-risk conditions, except those aged 18-64 years with heart disease (aOR 190, 95% CI 103-351). Of patients at high risk for influenza complications, self-reported ILI was greater but receipt of antiviral treatment was not, despite guidelines recommending their use in this population.
C1 [Biggerstaff, M.; Jhung, M. A.; Reed, C.; Garg, S.; Fry, A. M.; Finelli, L.] Ctr Dis Control & Prevent, Epidemiol & Prevent Branch, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
[Garg, S.] Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA.
[Balluz, L.] Ctr Dis Control & Prevent, Div Behav Surveillance, Off Surveillance Epidemiol & Lab Serv, Atlanta, GA 30333 USA.
RP Biggerstaff, M (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd NE MS A-32, Atlanta, GA 30333 USA.
EM MBiggerstaff@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 38
TC 4
Z9 4
U1 1
U2 2
PU CAMBRIDGE UNIV PRESS
PI NEW YORK
PA 32 AVENUE OF THE AMERICAS, NEW YORK, NY 10013-2473 USA
SN 0950-2688
EI 1469-4409
J9 EPIDEMIOL INFECT
JI Epidemiol. Infect.
PD JAN
PY 2014
VL 142
IS 1
BP 114
EP 125
DI 10.1017/S0950268813000654
PG 12
WC Public, Environmental & Occupational Health; Infectious Diseases
SC Public, Environmental & Occupational Health; Infectious Diseases
GA AC4XG
UT WOS:000332523900014
PM 23522400
ER
PT J
AU Cardemil, CV
Rathee, M
Gary, H
Wannemuehler, K
Anand, A
Mach, O
Bahl, S
Wassilak, S
Chu, SY
Khera, A
Jafari, HS
Pallansch, MA
AF Cardemil, C. V.
Rathee, M.
Gary, H.
Wannemuehler, K.
Anand, A.
Mach, O.
Bahl, S.
Wassilak, S.
Chu, S. Y.
Khera, A.
Jafari, H. S.
Pallansch, M. A.
TI Surveillance during an era of rapidly changing poliovirus epidemiology
in India: the role of one vs. two stool specimens in poliovirus
detection, 2000-2010
SO EPIDEMIOLOGY AND INFECTION
LA English
DT Article
DE Infectious disease epidemiology; laboratory tests; polio; surveillance;
surveillance system
ID ACUTE FLACCID PARALYSIS; WILD POLIOVIRUS; ERADICATION; SENSITIVITY;
AMERICA
AB Since 2004, efforts to improve poliovirus detection have significantly increased the volume of specimen testing from acute flaccid paralysis (AFP) patients in India. One option to decrease collection and testing burden would be collecting only a single stool specimen instead of two. We investigated stool specimen sensitivity for poliovirus detection in India to estimate the contribution of the second specimen. We reviewed poliovirus isolation data for 303984 children aged <15 years with AFP during 2000-2010. Using maximum-likelihood estimation, we determined specimen sensitivity of each stool specimen, combined sensitivity of both specimens, and sensitivity added by the second specimen. Of 5184 AFP patients with poliovirus isolates, 382 (7.4%) were identified only by the second specimen. Sensitivity was 91.4% for the first specimen and 84.5% for the second specimen; the second specimen added 7.3% sensitivity, giving a combined sensitivity of 987%. Combined sensitivity declined, and added sensitivity increased, as the time from paralysis onset to stool collection increased (P=0.032). The sensitivity added by the second specimen is important to detect the last chains of poliovirus transmission and to achieve certification of polio eradication. For sensitive surveillance, two stool specimens should continue to be collected from each AFP patient in India.
C1 [Cardemil, C. V.; Gary, H.; Wannemuehler, K.; Anand, A.; Mach, O.; Wassilak, S.; Chu, S. Y.] Ctr Dis Control & Prevent, Global Immunizat Div, Ctr Global Hlth, Atlanta, GA 30333 USA.
[Cardemil, C. V.] Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA.
[Rathee, M.; Bahl, S.; Jafari, H. S.] World Hlth Org India, Natl Polio Surveillance Project, New Delhi, India.
[Khera, A.] Govt India, Minist Hlth & Family Welf, New Delhi, India.
[Pallansch, M. A.] Ctr Dis Control & Prevent, Div Viral Dis, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
RP Cardemil, CV (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd, Atlanta, GA 30333 USA.
EM ccardemil@cdc.gov
NR 20
TC 3
Z9 3
U1 1
U2 1
PU CAMBRIDGE UNIV PRESS
PI NEW YORK
PA 32 AVENUE OF THE AMERICAS, NEW YORK, NY 10013-2473 USA
SN 0950-2688
EI 1469-4409
J9 EPIDEMIOL INFECT
JI Epidemiol. Infect.
PD JAN
PY 2014
VL 142
IS 1
BP 163
EP 171
DI 10.1017/S0950268813000800
PG 9
WC Public, Environmental & Occupational Health; Infectious Diseases
SC Public, Environmental & Occupational Health; Infectious Diseases
GA AC4XG
UT WOS:000332523900020
PM 23594458
ER
PT J
AU Fuhr, DC
Fleischmann, A
Riley, L
Kann, L
Poznyak, V
AF Fuhr, Daniela Christina
Fleischmann, Alexandra
Riley, Leanne
Kann, Laura
Poznyak, Vladimir
TI Alcohol and other psychoactive substances in Africa and the Americas:
results from the WHO Global School-based Student Health Survey
SO JOURNAL OF SUBSTANCE USE
LA English
DT Article
DE Adolescence; alcohol; drugs
ID UNITED-STATES; CIGARETTE USE; RISK-FACTOR; TOBACCO USE; DRUG-USE;
SMOKING; CONSUMPTION; DRINKING; ADOLESCENTS; DEPENDENCE
AB Objective: The objective of this study was to estimate the prevalence of current alcohol use and its association with cigarette and drug use among 13-15-year-olds in Africa and the Americas.
Method: Cross-sectional data of the WHO Global School-based Student Health Survey from nine countries in the WHO African Region and seven countries/territories in the WHO Region of the Americas were analysed. Single and joint prevalence rates, and prevalence odds ratios were computed.
Results: In the majority of countries, alcohol was the most often consumed psychoactive substance, with the prevalence of current alcohol use outweighing the prevalence of current cigarette and lifetime drug use. Gender differences for alcohol were not marked. The use of alcohol was strongly associated with cigarette or drug use, indicating clustering.
Conclusions: For the bulk of countries in the Americas and for single countries in Africa, current alcohol use is as high as prevalence rates occurring in other parts of the world. It is imperative to monitor psychoactive substance use among adolescents in these countries to be able to prevent future health and social harm with the information gained.
C1 [Fuhr, Daniela Christina] London Sch Hyg & Trop Med, Ctr Global Mental Hlth, London, England.
[Fleischmann, Alexandra; Poznyak, Vladimir] WHO, Dept Mental Hlth & Subst Abuse, CH-1211 Geneva, Switzerland.
[Riley, Leanne] WHO, Dept Chron Dis & Hlth Promot Surveillance & Popul, CH-1211 Geneva, Switzerland.
[Kann, Laura] US Ctr Dis Control & Prevent, Div Adolescent & Sch Hlth, Atlanta, GA USA.
RP Fuhr, DC (reprint author), London Sch Hyg & Trop Med, Ctr Global Mental Hlth, London, England.
EM Daniela.Fuhr@lshtm.ac.uk
NR 32
TC 1
Z9 1
U1 0
U2 4
PU INFORMA HEALTHCARE
PI NEW YORK
PA 52 VANDERBILT AVE, NEW YORK, NY 10017 USA
SN 1465-9891
EI 1475-9942
J9 J SUBST USE
JI J. Subst. Use
PY 2014
VL 19
IS 3
BP 274
EP 282
DI 10.3109/14659891.2013.824038
PG 9
WC Substance Abuse
SC Substance Abuse
GA AG5FP
UT WOS:000335445200009
ER
PT J
AU Kitahara, CM
Linet, MS
Brenner, AV
Wang, SS
Melin, BS
Wang, ZM
Inskip, PD
Freeman, LEB
Braganza, MZ
Carreon, T
Feychting, M
Gaziano, JM
Peters, U
Purdue, MP
Ruder, AM
Sesso, HD
Shu, XO
Waters, MA
White, E
Zheng, W
Hoover, RN
Fraumeni, JF
Chatterjee, N
Yeager, M
Chanock, SJ
Hartge, P
Rajaraman, P
AF Kitahara, Cari M.
Linet, Martha S.
Brenner, Alina V.
Wang, Sophia S.
Melin, Beatrice S.
Wang, Zhaoming
Inskip, Peter D.
Freeman, Laura E. Beane
Braganza, Melissa Z.
Carreon, Tania
Feychting, Maria
Gaziano, J. Michael
Peters, Ulrike
Purdue, Mark P.
Ruder, Avima M.
Sesso, Howard D.
Shu, Xiao-Ou
Waters, Martha A.
White, Emily
Zheng, Wei
Hoover, Robert N.
Fraumeni, Joseph F., Jr.
Chatterjee, Nilanjan
Yeager, Meredith
Chanock, Stephen J.
Hartge, Patricia
Rajaraman, Preetha
TI Personal History of Diabetes, Genetic Susceptibility to Diabetes, and
Risk of Brain Glioma: A Pooled Analysis of Observational Studies
SO CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
LA English
DT Article
ID GENOME-WIDE ASSOCIATION; CENTRAL-NERVOUS-SYSTEM; INSULIN-RESISTANCE;
PHYSICIANS HEALTH; CANCER INCIDENCE; TUMORS; VARIANTS; MELLITUS; COHORT;
LOCI
AB Background: Brain glioma is a relatively rare and fatal malignancy in adulthood with few known risk factors. Some observational studies have reported inverse associations between diabetes and subsequent glioma risk, but possible mechanisms are unclear.
Methods: We conducted a pooled analysis of original data from five nested case-control studies and two case-control studies from the United States and China that included 962 glioma cases and 2,195 controls. We examined self-reported diabetes history in relation to glioma risk, as well as effect modification by seven glioma risk associated single-nucleotide polymorphisms(SNP). We also examined the associations between 13 diabetes risk associated SNPs, identified from genome-wide association studies, and glioma risk. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using multivariable-adjusted logistic regression models.
Results: We observed a 42% reduced risk of glioma for individuals with a history of diabetes (OR = 0.58; 95% CI, 0.40-0.84). The association did not differ by sex, study design, or after restricting to glioblastoma, the most common histological subtype. We did not observe any significant per-allele trends among the 13 diabetes related SNPs examined in relation to glioma risk.
Conclusion: These results support an inverse association between diabetes history and glioma risk. The role of genetic susceptibility to diabetes cannot be excluded, and should be pursued in future studies together with other factors that might be responsible for the diabetes-glioma association.
Impact: These data suggest the need for studies that can evaluate, separately, the association between type 1 and type 2 diabetes and subsequent risk of adult glioma. Cancer Epidemiol Biomarkers Prev; 23(1); 47-54. (C) 2013 AACR.
C1 [Kitahara, Cari M.; Linet, Martha S.; Brenner, Alina V.; Wang, Zhaoming; Inskip, Peter D.; Freeman, Laura E. Beane; Braganza, Melissa Z.; Purdue, Mark P.; Hoover, Robert N.; Fraumeni, Joseph F., Jr.; Chatterjee, Nilanjan; Yeager, Meredith; Chanock, Stephen J.; Hartge, Patricia; Rajaraman, Preetha] NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
[Wang, Zhaoming; Yeager, Meredith; Chanock, Stephen J.] SAIC Frederick Inc, Core Genotyping Facil, NCI, Gaithersburg, MD USA.
[Wang, Sophia S.] City Hope & Beckman Res Inst, Dept Populat Sci, Div Canc Etiol, Duarte, CA USA.
[Carreon, Tania; Ruder, Avima M.; Waters, Martha A.] NIOSH, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA.
[Gaziano, J. Michael; Sesso, Howard D.] Harvard Univ, Brigham & Womens Hosp, Div Prevent Med, Sch Med, Boston, MA 02115 USA.
[Gaziano, J. Michael; Sesso, Howard D.] Harvard Univ, Brigham & Womens Hosp, Div Aging, Sch Med, Boston, MA 02115 USA.
[Gaziano, J. Michael] VA Boston Healthcare Syst, Geriatr Res Educ & Clin Ctr, Res & Informat Ctr, Massachusetts Vet Epidemiol, Boston, MA USA.
[Peters, Ulrike] Univ Washington, Fred Hutchinson Canc Res Ctr, Seattle, WA 98195 USA.
[Peters, Ulrike; White, Emily] Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA.
[Shu, Xiao-Ou; Zheng, Wei] Vanderbilt Univ, Med Ctr, Nashville, TN USA.
[Melin, Beatrice S.] Umea Univ, Dept Radiat Sci, Umea, Sweden.
[Feychting, Maria] Karolinska Inst, Inst Environm Med, S-10401 Stockholm, Sweden.
RP Kitahara, CM (reprint author), Div Canc Epidemiol & Genet, 9609 Med Ctr Dr,Room 7E-566, Bethesda, MD 20892 USA.
EM meinholdc@mail.nih.gov
RI Purdue, Mark/C-9228-2016; Kitahara, Cari/R-8267-2016
OI Purdue, Mark/0000-0003-1177-3108;
FU National Institutes of Health [CA 97193, CA 34944, CA 40360, HL 26490,
HL 34595]; Division of Cancer Epidemiology and Genetics; Division of
Cancer Prevention; National Cancer Institute; NIH; DHHS; NIOSH operating
funds; National Cancer Institute [K05CA154337]; NIH Office of Dietary
Supplements
FX The authors thank all investigators who contributed data for the
GliomaScan study.; For PHS: The PHS is supported by grants CA 97193, CA
34944, CA 40360, HL 26490, and HL 34595 from the National Institutes of
Health. For PLCO: This research was supported by the Intramural Research
Program of the Division of Cancer Epidemiology and Genetics and by
contracts from the Division of Cancer Prevention, National Cancer
Institute, NIH, DHHS.; For NIOSH: This research was supported by NIOSH
operating funds. The contributions of former laboratory director Mary
Ann Butler are gratefully acknowledged. The findings and conclusions in
this report are those of the author(s) and do not necessarily represent
the views of the National Institute for Occupational Safety and Health.;
For VITAL: Grant K05CA154337 is funded by the National Cancer Institute
(NCI) and the NIH Office of Dietary Supplements (ODS).
NR 37
TC 10
Z9 10
U1 0
U2 7
PU AMER ASSOC CANCER RESEARCH
PI PHILADELPHIA
PA 615 CHESTNUT ST, 17TH FLOOR, PHILADELPHIA, PA 19106-4404 USA
SN 1055-9965
EI 1538-7755
J9 CANCER EPIDEM BIOMAR
JI Cancer Epidemiol. Biomarkers Prev.
PD JAN
PY 2014
VL 23
IS 1
BP 47
EP 54
DI 10.1158/1055-9965.EPI-13-0913
PG 8
WC Oncology; Public, Environmental & Occupational Health
SC Oncology; Public, Environmental & Occupational Health
GA AG0ZB
UT WOS:000335143400006
PM 24220915
ER
PT J
AU Tauxe, RV
AF Tauxe, Robert V.
TI Cholera: fourth year of the epidemic in Haiti; sixth decade of the
global pandemic
SO PATHOGENS AND GLOBAL HEALTH
LA English
DT Editorial Material
C1 Ctr Dis Control & Prevent, Div Foodborne Waterborne & Environm Dis, Atlanta, GA 30333 USA.
RP Tauxe, RV (reprint author), Ctr Dis Control & Prevent, Div Foodborne Waterborne & Environm Dis, MS C-09,1600 Clifton Rd, Atlanta, GA 30333 USA.
EM rvt1@cdc.gov
NR 5
TC 0
Z9 0
U1 0
U2 4
PU MANEY PUBLISHING
PI LEEDS
PA STE 1C, JOSEPHS WELL, HANOVER WALK, LEEDS LS3 1AB, W YORKS, ENGLAND
SN 2047-7724
EI 2047-7732
J9 PATHOG GLOB HEALTH
JI Pathog. Glob. Health
PD JAN
PY 2014
VL 108
IS 1
BP 1
EP 2
DI 10.1179/2047772413Z.000000000168
PG 2
WC Public, Environmental & Occupational Health; Parasitology; Tropical
Medicine
SC Public, Environmental & Occupational Health; Parasitology; Tropical
Medicine
GA AG5ET
UT WOS:000335442900001
PM 24548153
ER
PT J
AU Ali, A
Jafri, RZ
Messonnier, N
Tevi-Benissan, C
Durrheim, D
Eskola, J
Fermon, F
Klugman, KP
Ramsay, M
Sow, S
Shao, ZJ
Bhutta, Z
Abramson, J
AF Ali, Asad
Jafri, Rabab Zehra
Messonnier, Nancy
Tevi-Benissan, Carol
Durrheim, David
Eskola, Juhani
Fermon, Florence
Klugman, Keith P.
Ramsay, Mary
Sow, Samba
Shao Zhujun
Bhutta, Zulfiqar
Abramson, Jon
TI Global practices of meningococcal vaccine use and impact on invasive
disease
SO PATHOGENS AND GLOBAL HEALTH
LA English
DT Review
DE Invasive meningococcal disease; Epidemiology; Vaccines; Immunization
schedule; Meningococcemia; Serogroup; Global; Immunity; Meningococcus;
Meningitis
ID C CONJUGATE VACCINE; MEMBRANE VESICLE VACCINE; RANDOMIZED
CONTROLLED-TRIAL; MENINGITIDIS SEROGROUP-C; NEISSERIA-MENINGITIDIS;
POLYSACCHARIDE VACCINE; UNITED-KINGDOM; IMMUNOLOGICAL MEMORY; GROUP-A;
ANTIBODY PERSISTENCE
AB A number of countries now include meningococcal vaccines in their routine immunization programs. This review focuses on different approaches to including meningococcal vaccines in country programs across the world and their effect on the burden of invasive meningococcal disease (IMD) as reflected by pre and post-vaccine incidence rates in the last 20 years. Mass campaigns using conjugated meningococcal vaccines have lead to control of serogroup C meningococcal disease in the UK, Canada, Australia, Spain, Belgium, Ireland, and Iceland. Serogroup B disease, predominant in New Zealand, has been dramatically decreased, partly due to the introduction of an outer membrane vesicle (OMV) vaccine. Polysaccharide vaccines were used in high risk people in Saudi Arabia and Syria and in routine immunization in China and Egypt. The highest incidence region of the meningitis belt initiated vaccination with the serogroup A conjugate vaccine in 2010 and catch-up vaccination is ongoing. Overall results of this vaccine introduction are encouraging especially in countries with a moderate to high level of endemic disease. Continued surveillance is required to monitor effectiveness in countries that recently implemented these programs.
C1 [Ali, Asad; Jafri, Rabab Zehra] Aga Khan Univ, Dept Paediat & Child Hlth, Karachi, Pakistan.
[Jafri, Rabab Zehra] Univ Illinois, Chicago, IL USA.
[Messonnier, Nancy] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Tevi-Benissan, Carol] WHO, CH-1211 Geneva, Switzerland.
[Durrheim, David] Univ Newcastle, Sch Med & Publ Hlth, Callaghan, NSW 2308, Australia.
[Eskola, Juhani] Finnish Natl Inst Hlth & Welf THL, Helsinki, Finland.
[Fermon, Florence] Med Sans Frontieres, Int Vaccinat Working Grp, Paris, France.
[Klugman, Keith P.] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA.
[Klugman, Keith P.] Univ Witwatersrand, Johannesburg, South Africa.
[Klugman, Keith P.] MRC, Resp & Meningeal Pathogens Res Unit, Johannesburg, South Africa.
[Ramsay, Mary] Hlth Protect Agcy, Ctr Infect Colindale, Immunisat Dept, London, England.
[Sow, Samba] Univ Maryland, Sch Med, Baltimore, MD 21201 USA.
[Bhutta, Zulfiqar] Aga Khan Univ, Div Women & Child Hlth, Karachi, Pakistan.
[Abramson, Jon] Wake Forest Med Sch, Winston Salem, NC USA.
RP Ali, A (reprint author), Aga Khan Univ, Dept Paediat & Child Hlth, Stadium Rd, Karachi, Pakistan.
EM asad.ali@aku.edu
FU World Health Organization [001]
NR 84
TC 14
Z9 15
U1 0
U2 7
PU MANEY PUBLISHING
PI LEEDS
PA STE 1C, JOSEPHS WELL, HANOVER WALK, LEEDS LS3 1AB, W YORKS, ENGLAND
SN 2047-7724
EI 2047-7732
J9 PATHOG GLOB HEALTH
JI Pathog. Glob. Health
PD JAN
PY 2014
VL 108
IS 1
BP 11
EP 20
DI 10.1179/2047773214Y.0000000126
PG 10
WC Public, Environmental & Occupational Health; Parasitology; Tropical
Medicine
SC Public, Environmental & Occupational Health; Parasitology; Tropical
Medicine
GA AG5ET
UT WOS:000335442900004
PM 24548156
ER
PT J
AU Hojgaard, A
Lukacik, G
Piesman, J
AF Hojgaard, Andrias
Lukacik, Gary
Piesman, Joseph
TI Detection of Borrelia burgdorferi, Anaplasma phagocytophilum and Babesia
microti, with two different multiplex PCR assays
SO TICKS AND TICK-BORNE DISEASES
LA English
DT Article
DE Multiplex PCR; Ticks; Pathogens
ID TICKS
AB We have developed 2 real-time multiplex PCR assays for detection of Borrelia burgdorferi, Anaplasma phagocytophilum, and Babesia microti. The efficiency and sensitivity of each multiplex PCR assay was evaluated using field-collected Ixodes scapularis ticks that were positive for each of the pathogens, cloned plasmids harboring each of the PCR targets, and laboratory I. scapularis infected with B. burgdorferi B31. There was no difference in efficiency or sensitivity when comparing the multiplex PCR with the individual PCR reactions. If the 2 multiplex PCR assays are used in the same analysis, field-collected ticks that only harbor B. miyamotoi can also be identified. The multiplex assays are fast and cost-effective methods for screening and detecting pathogens in ticks, when compared to single-target PCR. Published by Elsevier GmbH.
C1 [Hojgaard, Andrias; Piesman, Joseph] Ctr Dis Control & Prevent, Div Vector Borne Dis, Natl Ctr Emerging & Zoonot Infect Dis, Ft Collins, CO 80521 USA.
[Lukacik, Gary] New York State Dept Hlth, Bur Communicable Dis Control, Albany, NY USA.
RP Hojgaard, A (reprint author), Ctr Dis Control & Prevent, Div Vector Borne Infect Dis, 3156 Rampart Rd, Ft Collins, CO 80521 USA.
EM Fth3@cdc.gov
NR 7
TC 16
Z9 16
U1 1
U2 11
PU ELSEVIER GMBH, URBAN & FISCHER VERLAG
PI JENA
PA OFFICE JENA, P O BOX 100537, 07705 JENA, GERMANY
SN 1877-959X
EI 1877-9603
J9 TICKS TICK-BORNE DIS
JI Ticks Tick-Borne Dis.
PY 2014
VL 5
IS 3
BP 349
EP 351
DI 10.1016/j.ttbdis.2013.12.001
PG 3
WC Infectious Diseases; Microbiology; Parasitology
SC Infectious Diseases; Microbiology; Parasitology
GA AG2ZS
UT WOS:000335286200020
PM 24507434
ER
PT J
AU Tucker, SP
AF Tucker, Samuel P.
TI Development, evaluation and comparison of two independent sampling and
analytical methods for ortho-phthalaldehyde vapors and condensation
aerosols in air
SO ANALYTICAL METHODS
LA English
DT Article
ID PERFORMANCE LIQUID-CHROMATOGRAPHY; ANAPHYLAXIS FOLLOWING CYSTOSCOPY;
2,4-DINITROPHENYLHYDRAZINE-IMPREGNATED SILICA; DISINFECTION; CARTRIDGE;
OZONE
AB Two independent sampling and analytical methods for ortho-phthalaldehyde (OPA) in air have been developed, evaluated and compared: (1) a reagent-coated solid sorbent HPLC-UV method and (2) an impinger-fluorescence method. In the first method, air sampling is conducted at 1.0 L min(-1) with a sampler containing 350 mg of silica gel coated with 1 mg of acidified 2,4-dinitrophenylhydrazine (DNPH). After sampling, excess DNPH in ethyl acetate is added to the sampler prior to storage for 68 hours. The OPA-DNPH derivative is eluted with 4.0 mL of dimethyl sulfoxide (DMSO) for measurement by HPLC with a UV detector set at 385 nm. The estimated detection limit is 0.016 mu g per sample or 0.067 mu g m(-3) (0.012 ppb) for a 240 L air sample. Recoveries of vapor spikes at levels of 1.2 to 6.2 mu g were 96 to 101%. Recoveries of spikes as mixtures of vapor and condensation aerosols were 97 to 100%. In the second method, air sampling is conducted at 1.0 L min(-1) with a midget impinger containing 10 mL of DMSO solution containing N-acetyl-L-cysteine and ethylenediamine. The fluorescence reading is taken 80 min after the completion of air sampling. Since the time of taking the fluorescence reading is critical, the reading is taken with a portable fluorometer. The estimated detection limit is 0.024 mu g per sample or 0.1 mu g m(-3) (0.018 ppb) for a 240 L air sample. Recoveries of OPA vapor spikes at levels of 1.4 to 5.0 mu g per sample were 97 to 105%. Recoveries of spikes as mixtures of vapors and condensation aerosols were 95 to 99%. The collection efficiency for a mixture of vapor and condensation aerosol was 99.4%. The two methods were compared side-by-side in a generation system constructed for producing controlled atmospheres of OPA vapor in air. Average air concentrations of OPA vapor found by both methods agreed within +/- 10%.
C1 NIOSH, Cincinnati, OH 45226 USA.
RP Tucker, SP (reprint author), NIOSH, Cincinnati, OH 45226 USA.
EM sptucker@fuse.net
NR 23
TC 0
Z9 0
U1 1
U2 2
PU ROYAL SOC CHEMISTRY
PI CAMBRIDGE
PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS,
ENGLAND
SN 1759-9660
EI 1759-9679
J9 ANAL METHODS-UK
JI Anal. Methods
PY 2014
VL 6
IS 8
BP 2592
EP 2607
DI 10.1039/c3ay42085j
PG 16
WC Chemistry, Analytical; Food Science & Technology; Spectroscopy
SC Chemistry; Food Science & Technology; Spectroscopy
GA AD8NZ
UT WOS:000333524200024
ER
PT J
AU Knaack, JS
Hamelin, EI
Magnuson, M
Silvestri, E
Ash, D
Johnson, RC
AF Knaack, Jennifer S.
Hamelin, Elizabeth I.
Magnuson, Matthew
Silvestri, Erin
Ash, Doris
Johnson, Rudolph C.
TI Quantitative analysis and stability of the rodenticide TETS (tetramine)
in finished tap water
SO ANALYTICAL METHODS
LA English
DT Article
ID CHROMATOGRAPHY-MASS-SPECTROMETRY; GAS-CHROMATOGRAPHY; HUMAN BLOOD;
TETRAMETHYLENE DISULFOTETRAMINE; GC FPD; TETRAMETHYLENEDISULFOTETRAMINE;
FOOD; PHARMACOLOGY; AGENT
AB The determination of the rodenticide tetramethylenedisulfotetramine (TETS) in drinking water is reportable through the use of automated sample preparation via solid phase extraction and detection using isotope dilution gas chromatography-mass spectrometry. The method was characterized over twenty-two analytical batches with quality control samples. Accuracies for low and high concentration quality control pools were 100 and 101%, respectively. The minimum reporting level (MRL) for TETS in this method is 0.50 mu g L-1. Five drinking waters representing a range of water quality parameters and disinfection practices were fortified with TETS at ten times the MRL and analyzed over a 28 day period to determine the stability of TETS in these waters. The amount of TETS measured in these samples averaged 100 +/- 6% of the amount fortified suggesting that tap water samples may be held for up to 28 days prior to analysis.
C1 [Knaack, Jennifer S.; Hamelin, Elizabeth I.; Ash, Doris; Johnson, Rudolph C.] Ctr Dis Control & Prevent, Emergency Response Branch, Div Sci Lab, Natl Ctr Environm Hlth, Atlanta, GA 30341 USA.
[Magnuson, Matthew; Silvestri, Erin] US EPA, Natl Homeland Secur Res Ctr, Cincinnati, OH 45268 USA.
RP Johnson, RC (reprint author), Ctr Dis Control & Prevent, Emergency Response Branch, Div Sci Lab, Natl Ctr Environm Hlth, 4770 Buford Highway,MS F-44, Atlanta, GA 30341 USA.
EM RJohnson6@cdc.gov
FU USEPA, through its Office of Research and Development; CDC; EPA
[DW75-92259701]
FX The authors would like to thank Benjamin Ku for assisting with graphical
editing. The research described herein has been peer and
administratively reviewed and has been approved for publication as a
joint U.S. Environmental Protection Agency (EPA) and Centers for Disease
Control and Prevention (CDC) document. The USEPA, through its Office of
Research and Development, funded and collaborated with the CDC in the
research described herein under EPA IA# DW75-92259701. Note that
approval does not signify that the contents necessarily reflect the
views of the USEPA, the CDC, the Public Health Service, or the US
Department of Health and Human Services. Reference herein to any
specific commercial product, process, or service by trade name,
trademark, manufacturer, or otherwise does not necessarily constitute or
imply its endorsement, recommendation, or favoring by the United States
government. The views and opinions expressed herein do not necessarily
state or reflect those of the United States government and shall not be
used for advertising or product endorsement purposes.
NR 29
TC 0
Z9 0
U1 2
U2 11
PU ROYAL SOC CHEMISTRY
PI CAMBRIDGE
PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS,
ENGLAND
SN 1759-9660
EI 1759-9679
J9 ANAL METHODS-UK
JI Anal. Methods
PY 2014
VL 6
IS 8
BP 2780
EP 2784
DI 10.1039/c3ay41912f
PG 5
WC Chemistry, Analytical; Food Science & Technology; Spectroscopy
SC Chemistry; Food Science & Technology; Spectroscopy
GA AD8NZ
UT WOS:000333524200049
ER
PT J
AU Jagannathan, P
Eccles-James, I
Bowen, K
Nankya, F
Auma, A
Wamala, S
Ebusu, C
Muhindo, MK
Arinaitwe, E
Briggs, J
Greenhouse, B
Tappero, JW
Kamya, MR
Dorsey, G
Feeney, ME
AF Jagannathan, Prasanna
Eccles-James, Ijeoma
Bowen, Katherine
Nankya, Felistas
Auma, Ann
Wamala, Samuel
Ebusu, Charles
Muhindo, Mary K.
Arinaitwe, Emmanuel
Briggs, Jessica
Greenhouse, Bryan
Tappero, Jordan W.
Kamya, Moses R.
Dorsey, Grant
Feeney, Margaret E.
TI IFN gamma/IL-10 Co-producing Cells Dominate the CD4 Response to Malaria
in Highly Exposed Children
SO PLOS PATHOGENS
LA English
DT Article
ID PLASMODIUM-FALCIPARUM MALARIA; REGULATORY T-CELLS; IFN-GAMMA; CLINICAL
MALARIA; CIRCUMSPOROZOITE PROTEIN; SPOROZOITE INOCULATION; LYMPHATIC
FILARIASIS; IMMUNE-RESPONSES; IL-10 PRODUCTION; VIRAL CLEARANCE
AB Although evidence suggests that T cells are critical for immunity to malaria, reliable T cell correlates of exposure to and protection from malaria among children living in endemic areas are lacking. We used multiparameter flow cytometry to perform a detailed functional characterization of malaria-specific T cells in 78 four-year-old children enrolled in a longitudinal cohort study in Tororo, Uganda, a highly malaria-endemic region. More than 1800 episodes of malaria were observed in this cohort, with no cases of severe malaria. We quantified production of IFN, TNF, and IL-10 (alone or in combination) by malaria-specific T cells, and analyzed the relationship of this response to past and future malaria incidence. CD4(+) T cell responses were measurable in nearly all children, with the majority of children having CD4(+) T cells producing both IFN and IL-10 in response to malaria-infected red blood cells. Frequencies of IFN/IL10 co-producing CD4(+) T cells, which express the Th1 transcription factor T-bet, were significantly higher in children with 2 prior episodes/year compared to children with <2 episodes/year (P<0.001) and inversely correlated with duration since malaria (Rho=-0.39, P<0.001). Notably, frequencies of IFN/IL10 co-producing cells were not associated with protection from future malaria after controlling for prior malaria incidence. In contrast, children with <2 prior episodes/year were significantly more likely to exhibit antigen-specific production of TNF without IL-10 (P=0.003). While TNF-producing CD4(+) T cells were not independently associated with future protection, the absence of cells producing this inflammatory cytokine was associated with the phenotype of asymptomatic infection. Together these data indicate that the functional phenotype of the malaria-specific T cell response is heavily influenced by malaria exposure intensity, with IFN/IL10 co-producing CD4(+) T cells dominating this response among highly exposed children. These CD4(+) T cells may play important modulatory roles in the development of antimalarial immunity.
Author Summary Despite reports of decreasing malaria morbidity across many parts of Africa, the incidence of malaria among children continues to be very high in Uganda, even in the setting of insecticide-treated bednets and artemisinin-based combination therapy. Additional control measures, including a vaccine, are sorely needed in these settings, but progress has been limited by our lack of understanding of immunologic correlates of exposure and protection. T cell responses to malaria are thought to be important for protection in experimental models, but their role in protecting against naturally acquired infection is not clear. In this study, we performed detailed assessments of the malaria-specific T cell response among 4-year-old children living in Tororo, Uganda, an area of high malaria transmission. We found that recent malaria infection induces a malaria-specific immune response dominated by Th1 T cells co-producing IFN and IL-10, and that these cells are not associated with protection from future infection. IFN/IL-10 co-producing cells have been described in several parasitic infections and are hypothesized to be important in limiting CD4-mediated pathology, but they may also prevent the development of sterilizing immunity. These observations have important implications for understanding the pathophysiology of malaria in humans and for malaria vaccine development.
C1 [Jagannathan, Prasanna; Eccles-James, Ijeoma; Bowen, Katherine; Briggs, Jessica; Greenhouse, Bryan; Dorsey, Grant; Feeney, Margaret E.] Univ Calif San Francisco, San Francisco Gen Hosp, Dept Med, San Francisco, CA 94143 USA.
[Nankya, Felistas; Auma, Ann; Wamala, Samuel; Ebusu, Charles; Muhindo, Mary K.; Arinaitwe, Emmanuel] Infect Dis Res Collaborat, Kampala, Uganda.
[Tappero, Jordan W.] Ctr Dis Control & Prevent, Ctr Global Hlth, Atlanta, GA USA.
[Kamya, Moses R.] Makerere Univ, Coll Hlth Sci, Dept Med, Kampala, Uganda.
[Feeney, Margaret E.] Univ Calif San Francisco, Dept Pediat, San Francisco, CA USA.
RP Feeney, ME (reprint author), Univ Calif San Francisco, San Francisco Gen Hosp, Dept Med, San Francisco, CA 94143 USA.
EM margaret.feeney@ucsf.edu
OI Greenhouse, Bryan/0000-0003-0287-9111
FU Centers for Disease Control and Prevention [U62P024421]; NIH/NIAID
[R01AI093615, U19AI089674, K23 AI100949]; UCSF Centers for AIDS Research
[P30AI027763]; Burroughs Wellcome Fund/American Society of Tropical
Medicine and Hygiene; National Center for Advancing Translational
Sciences/NIH, through UCSF-CTSI [UL1 TR000004]
FX This work was supported by the Centers for Disease Control and
Prevention (Cooperative Agreement No U62P024421); NIH/NIAID R01AI093615
(MEF), UCSF Centers for AIDS Research (Supplement to MEF, P30AI027763),
NIH/NIAID U19AI089674 (GD), NIH/NIAID K23 AI100949 (PJ), and Burroughs
Wellcome Fund/American Society of Tropical Medicine and Hygiene (PJ).
Additional support was provided by the National Center for Advancing
Translational Sciences/NIH, through UCSF-CTSI Grant Number UL1 TR000004.
The funders had no role in study design, data collection and analysis,
decision to publish, or preparation of the manuscript. The findings and
conclusions in this paper are those of the authors and do not
necessarily represent the official position of the Centers for Disease
Control and Prevention or the NIH.
NR 91
TC 36
Z9 36
U1 0
U2 2
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1553-7366
EI 1553-7374
J9 PLOS PATHOG
JI PLoS Pathog.
PD JAN
PY 2014
VL 10
IS 1
AR e1003864
DI 10.1371/journal.ppat.1003864
PG 14
WC Microbiology; Parasitology; Virology
SC Microbiology; Parasitology; Virology
GA AC6NQ
UT WOS:000332640900031
PM 24415936
ER
PT J
AU Azziz-Baumgartner, E
Homaira, N
Hamadani, JD
Tofail, F
Dahlberg, LL
Haque, R
Luby, SP
Naved, RT
AF Azziz-Baumgartner, Eduardo
Homaira, Nusrat
Hamadani, J. D.
Tofail, Fahmida
Dahlberg, Linda L.
Haque, Rashidul
Luby, Stephen P.
Naved, Ruchira T.
TI The Prevalence and Impact of Intimate Partner Violence on Maternal
Distress in a Community of Low-Income Bangladeshi and Displaced Ethnic
Bihari Mothers: Dhaka, 2008-2009
SO VIOLENCE AGAINST WOMEN
LA English
DT Article
DE Bangladesh; intimate partner violence prevalence rates
ID DOMESTIC VIOLENCE; MENTAL-HEALTH; WOMENS HEALTH; PREGNANCY;
MULTICOUNTRY; WEIGHT; ABUSE
AB Low-income, ethnic, and/or displaced mothers are frequently victimized; we explored the burden of intimate partner violence (IPV) among such women. Teams administered IPV and maternal distress questionnaires to quantify victimization after the birth of a child. Of 250 mothers reporting abuse, 133 (53%) reported their husband hitting; 111 (44%) kicking, dragging, or beating; 61 (24%) choking or burning; and 33 (13%) injuring them with a knife or gun (12 case-patients per 100 person-years). Women who experienced more forms of victimization reported more distress (p = .01). Mothers in this low-income community experienced severe victimization and distress.
C1 [Azziz-Baumgartner, Eduardo; Dahlberg, Linda L.; Luby, Stephen P.] US Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
[Azziz-Baumgartner, Eduardo; Homaira, Nusrat; Hamadani, J. D.; Tofail, Fahmida; Haque, Rashidul; Luby, Stephen P.; Naved, Ruchira T.] Int Ctr Diarrhoeal Dis Res, Dhaka, Bangladesh.
RP Azziz-Baumgartner, E (reprint author), US Ctr Dis Control & Prevent, 1600 Clifton Rd.,NE,MS A32, Atlanta, GA 30333 USA.
EM eha9@cdc.gov
OI Luby, Stephen/0000-0001-5385-899X
FU NCPDCID CDC HHS [U01/CI000628-02]; NIAID NIH HHS [5R01 AI043596]
NR 30
TC 1
Z9 1
U1 0
U2 4
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1077-8012
EI 1552-8448
J9 VIOLENCE AGAINST WOM
JI Violence Against Women
PD JAN
PY 2014
VL 20
IS 1
BP 59
EP 73
DI 10.1177/1077801213520579
PG 15
WC Women's Studies
SC Women's Studies
GA AB3KS
UT WOS:000331690300005
PM 24567536
ER
PT J
AU Elliott, JC
Aharonoyich, E
O'Leary, A
Wainberg, M
Hasin, DS
AF Elliott, Jennifer C.
Aharonoyich, Efrat
O'Leary, Ann
Wainberg, Milton
Hasin, Deborah S.
TI Drinking motives as prospective predictors of outcome in an intervention
trial with heavily drinking HIV patients
SO DRUG AND ALCOHOL DEPENDENCE
LA English
DT Article
DE HIV; AIDS; Drinking; Alcohol; Prediction; Motives
ID ALCOHOL-USE DISORDER; INTERVIEW SCHEDULE AUDADIS; ACTIVE ANTIRETROVIRAL
THERAPY; RANDOMIZED CONTROLLED-TRIAL; GENERAL-POPULATION SAMPLE;
SUBSTANCE USE; DSM-IV; INFECTED PATIENTS; UNITED-STATES; BEHAVIORAL
INTERVENTION
AB Background: Heavy alcohol consumption in HIV patients is an increasing health concern. Applying the drinking motivational model to HIV primary care patients, drinking motives (drinking to cope with negative affect, for social facilitation, and in response to social pressure) were associated with alcohol consumption at a baseline interview. However, whether these motives predict continued heavy drinking or alcohol dependence in this population is unknown.
Methods: Participants were 254 heavy-drinking urban HIV primary care patients (78.0% male; 94.5% African American or Hispanic) participating in a randomized trial of brief drinking-reduction interventions. Drinking motive scales, as well as measures of alcohol consumption and alcohol dependence, were administered at baseline. Consumption and dependence measures were re-administered at the end of treatment two months later. Regression analyses tested whether baseline drinking motive scale scores predicted continued heavy drinking and alcohol dependence status at the end of treatment, and whether motives interacted with treatment condition.
Results: Baseline drinking to cope with negative affect predicted continued heavy drinking (p < 0.05) and alcohol dependence, the latter in both in the full sample (adjusted odds ratio [AOR] = 2.14) and among those with baseline dependence (AOR = 2.52). Motives did not interact with treatment condition in predicting alcohol outcomes.
Conclusions: Drinking to cope with negative affect may identify HIV patients needing targeted intervention to reduce drinking, and may inform development of more effective interventions addressing ways other than heavy drinking to cope with negative affect. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
C1 [Elliott, Jennifer C.; Hasin, Deborah S.] Columbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, New York, NY 10032 USA.
[Aharonoyich, Efrat; Wainberg, Milton; Hasin, Deborah S.] Columbia Univ, Dept Psychiat, Coll Phys & Surg, New York, NY 10032 USA.
[Aharonoyich, Efrat; Wainberg, Milton; Hasin, Deborah S.] New York State Psychiat Inst & Hosp, New York, NY 10032 USA.
[O'Leary, Ann] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
RP Hasin, DS (reprint author), Columbia Univ, Dept Psychiat, Coll Phys & Surg, 1051 Riverside Dr 123, New York, NY 10032 USA.
EM dsh2@columbia.edu
FU New York State Psychiatric Institute; [R01AA014323]; [K05AA014223];
[R01DA024606]; [T32DA031099]
FX This study was funded by grants R01AA014323, K05AA014223, R01DA024606,
T32DA031099, and the New York State Psychiatric Institute.
NR 45
TC 8
Z9 8
U1 2
U2 6
PU ELSEVIER IRELAND LTD
PI CLARE
PA ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000,
IRELAND
SN 0376-8716
EI 1879-0046
J9 DRUG ALCOHOL DEPEN
JI Drug Alcohol Depend.
PD JAN 1
PY 2014
VL 134
BP 290
EP 295
DI 10.1016/j.drugalcdep.2013.10.026
PG 6
WC Substance Abuse; Psychiatry
SC Substance Abuse; Psychiatry
GA AC3MI
UT WOS:000332425500039
PM 24286967
ER
PT J
AU Anderson, VP
Chun, H
AF Anderson, Vern Putz
Chun, Heekyoung
TI WORKPLACE HAZARDS AND PREVENTION OPTIONS FROM A NONRANDOM SAMPLE OF
RETAIL TRADE BUSINESSES
SO INTERNATIONAL JOURNAL OF OCCUPATIONAL SAFETY AND ERGONOMICS
LA English
DT Article
DE hazards; interventions; engineering controls; ergonomics; manual
materials handling
ID SAFETY CLIMATE; BACK INJURY; WORKERS; INTERVENTION; EQUIPMENT; PAIN
AB Employer commitment is a key factor in an effective safety program, yet limited research has focused on the safety priorities of retail store managers. To address this, the U.S. National Institute for Occupational Safety and Health recruited 4 experienced ergonomists, who met and interviewed 9 retailers in different parts of the eastern USA. The reports from the 9 interviews were used to document the hazards facing retailers and the interventions they attempted. Those interviewed were managers/owners of establishments that ranged from a small bakery with 11 employees to a supermarket with 85 or more employees. The main hazards across all establishments included overexertion, contact-with-objects, and falls-to-the-same-level. We also compared the retailers' perceptions of safety hazards with injuries from actual hazards as supplied by the U.S. Bureau of Labor Statistics. This report provides insight into the retailers' perceptions of safety hazards as well as their commitment to the prevention of workplace injuries.
C1 [Anderson, Vern Putz; Chun, Heekyoung] NIOSH, Cincinnati, OH 45226 USA.
RP Anderson, VP (reprint author), NIOSH, 4676 Columbia Pwky, Cincinnati, OH 45226 USA.
EM vep1@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 42
TC 0
Z9 0
U1 2
U2 8
PU CENTRAL INST LABOUR PROTECTION-NATL RESEARCH INST
PI WARSAW
PA UL CZERNIAKOWSKA 16, WARSAW, 00-701, POLAND
SN 1080-3548
J9 INT J OCCUP SAF ERGO
JI Int. J. Occup. Saf. Ergon.
PY 2014
VL 20
IS 1
BP 181
EP 195
PG 15
WC Ergonomics; Public, Environmental & Occupational Health
SC Engineering; Public, Environmental & Occupational Health
GA AD7XC
UT WOS:000333479800017
PM 24629880
ER
PT J
AU Josset, L
Zeng, H
Kelly, SM
Tumpey, TM
Katze, MG
AF Josset, Laurence
Zeng, Hui
Kelly, Sara M.
Tumpey, Terrence M.
Katze, Michael G.
TI Transcriptomic Characterization of the Novel Avian-Origin Influenza A
(H7N9) Virus: Specific Host Response and Responses Intermediate between
Avian (H5N1 and H7N7) and Human (H3N2) Viruses and Implications for
Treatment Options
SO MBIO
LA English
DT Article
ID BRONCHIAL EPITHELIAL-CELLS; SEQUENCE-ANALYSIS; RECEPTOR-BINDING; HUMAN
INFECTIONS; REPLICATION; MINOCYCLINE; TRANSMISSION; RESISTANCE;
OUTBREAK; FERRETS
AB A novel avian-origin H7N9 influenza A virus (IAV) emerged in China in 2013, causing mild to lethal human respiratory infections. H7N9 originated with multiple reassortment events between avian viruses and carries genetic markers of human adaptation. Determining whether H7N9 induces a host response closer to that with human or avian IAV is important in order to better characterize this emerging virus. Here we compared the human lung epithelial cell response to infection with A/Anhui/01/13 (H7N9) or highly pathogenic avian-origin H5N1, H7N7, or human seasonal H3N2 IAV. The transcriptomic response to H7N9 was highly specific to this strain but was more similar to the response to human H3N2 than to that to other avian IAVs. H7N9 and H3N2 both elicited responses related to eicosanoid signaling and chromatin modification, whereas H7N9 specifically induced genes regulating the cell cycle and transcription. Among avian IAVs, the response to H7N9 was closest to that elicited by H5N1 virus. Host responses common to H7N9 and the other avian viruses included the lack of induction of the antigen presentation pathway and reduced proinflammatory cytokine induction compared to that with H3N2. Repression of these responses could have an important impact on the immunogenicity and virulence of H7N9 in humans. Finally, using a genome-based drug repurposing approach, we identified several drugs predicted to regulate the host response to H7N9 that may act as potential antivirals, including several kinase inhibitors, as well as FDA-approved drugs, such as troglitazone and minocycline. Importantly, we validated that minocycline inhibited H7N9 replication in vitro, suggesting that our computational approach holds promise for identifying novel antivirals.
IMPORTANCE Whether H7N9 will be the next pandemic influenza virus or will persist and sporadically infect humans from its avian reservoir, similar to H5N1, is not known yet. High-throughput profiling of the host response to infection allows rapid characterization of virus-host interactions and generates many hypotheses that will accelerate understanding and responsiveness to this potential threat. We show that the cellular response to H7N9 virus is closer to that induced by H3N2 than to that induced by H5N1, reflecting the potential of this new virus for adaptation to humans. Importantly, dissecting the host response to H7N9 may guide host-directed antiviral development.
C1 [Josset, Laurence; Kelly, Sara M.; Katze, Michael G.] Univ Washington, Sch Med, Dept Microbiol, Seattle, WA 98195 USA.
[Zeng, Hui; Tumpey, Terrence M.] Ctr Dis Control & Prevent, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA USA.
RP Katze, MG (reprint author), Univ Washington, Sch Med, Dept Microbiol, Seattle, WA 98195 USA.
EM honey@u.washington.edu
RI Josset, Laurence/A-7960-2015
OI Josset, Laurence/0000-0002-7158-1186
FU NIH, NIAID network of Centers of Excellence in Influenza Research and
Surveillance (CEIRS) [HHSN266200700008C]
FX This project has been funded in whole or in part with federal funds from
the NIH, NIAID network of Centers of Excellence in Influenza Research
and Surveillance (CEIRS), under contract HHSN266200700008C.
NR 47
TC 10
Z9 10
U1 0
U2 21
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 2150-7511
J9 MBIO
JI mBio
PD JAN-FEB
PY 2014
VL 5
IS 1
AR e01102-13
DI 10.1128/mBio.01102-13
PG 12
WC Microbiology
SC Microbiology
GA AC4YF
UT WOS:000332526500028
PM 24496798
ER
PT J
AU Luckhaupt, SE
Sweeney, MH
Sestito, JP
Calvert, GM
AF Luckhaupt, Sara E.
Sweeney, Marie H.
Sestito, John P.
Calvert, Geoffrey M.
TI What is the true prevalence of carpal tunnel syndrome among US workers?
SO SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH
LA English
DT Letter
C1 [Luckhaupt, Sara E.; Sweeney, Marie H.; Sestito, John P.; Calvert, Geoffrey M.] NIOSH, Div Surveillance Hazard Evaluat & Field Studies, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA.
[Luckhaupt, Sara E.] NIOSH, Cincinnati, OH 45226 USA.
RP Luckhaupt, SE (reprint author), NIOSH, 4676 Columbia Pkwy,R-17, Cincinnati, OH 45226 USA.
EM sluckhaupt@cdc.gov
NR 2
TC 1
Z9 1
U1 1
U2 2
PU SCANDINAVIAN JOURNAL WORK ENVIRONMENT & HEALTH
PI HELSINKI
PA TOPELIUKSENKATU 41A, SF-00250 HELSINKI, FINLAND
SN 0355-3140
EI 1795-990X
J9 SCAND J WORK ENV HEA
JI Scand. J. Work Environ. Health
PD JAN
PY 2014
VL 40
IS 1
BP 100
EP 100
DI 10.5271/sjweh.3391
PG 1
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AD5VN
UT WOS:000333321400012
PM 24121819
ER
PT J
AU West, CA
Galloway, E
Niemeier, MT
AF West, Christine A.
Galloway, Ellen
Niemeier, Maureen T.
TI Resident Aggression Toward Staff at a Center for the Developmentally
Disabled
SO WORKPLACE HEALTH & SAFETY
LA English
DT Article
ID WORK-ENVIRONMENT; MINNESOTA NURSES; NURSING-HOMES; HEALTH; INJURIES;
IMPACT; VIOLENCE; CONSEQUENCES; ORGANIZATION; OVERTIME
AB Few studies have examined factors contributing to nonfatal assaults to staff working in residential care facilities. The authors evaluated resident assaults toward direct care/nursing staff at an Intermediate Care Facility for Individuals with Mental Retardation (ICF/MR), which included observations of work areas, employee interviews, calculation of injury and assault rates for 2004 to 2007 from Occupational Safety and Health Administration Logs, and review of state ICF/MR guidelines. Most staff interviewed reported having been injured during physical restraint of a resident and the average rate of injury from assault at the center evaluated was higher than the average national rates for the health care and social assistance sector for the same time period. The center lacked policies for a safe workplace. The authors recommended review and maintenance of workplace violence prevention policies and developing a post-incident response and evaluation program to assist staff in coping with the consequences of assault and/or occupational injury.
C1 [West, Christine A.; Galloway, Ellen; Niemeier, Maureen T.] NIOSH, Cincinnati, OH 43236 USA.
RP West, CA (reprint author), NIOSH, 3135 S Whitetree Circle, Cincinnati, OH 43236 USA.
EM cawest@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 40
TC 0
Z9 0
U1 1
U2 8
PU SLACK INC
PI THOROFARE
PA 6900 GROVE RD, THOROFARE, NJ 08086 USA
SN 2165-0799
EI 2165-0969
J9 WORKPLACE HEALTH SAF
JI Workplace Health Saf.
PD JAN
PY 2014
VL 62
IS 1
BP 19
EP 26
DI 10.3928/21650799-20131220-04
PG 8
WC Nursing
SC Nursing
GA AE2KU
UT WOS:000333802600004
PM 24571051
ER
PT J
AU Dorsey, KIA
Moritz, ED
Notari, EP
Schonberger, LB
Dodd, RY
AF Dorsey, Kern I. A.
Moritz, Erin D.
Notari, Edward P.
Schonberger, Lawrence B.
Dodd, Roger Y.
TI Survival of blood transfusion recipients identified by a look-back
investigation
SO BLOOD TRANSFUSION
LA English
DT Article
DE blood transfusion; post-transfusion survival; recipient survival;
transfusion recipients; year of transfusion
ID LONG-TERM SURVIVAL; CREUTZFELDT-JAKOB-DISEASE; HEPATITIS-C LOOKBACK;
SWEDEN; RISK
AB Background. Survival of blood transfusion recipients is a critical consideration in assessing the outcomes oftransfusion. Data from the USA on the short- and long-term survival of recipients are limited.
Materials and methods. Blood product recipients were identified through a look-back study of Creutzfeldt-Jakob disease. Survival data were obtained from searches of the National Death Index or the Social Security Death Master File. Short- and long-term survival of recipients was analysed through descriptive statistics, Kaplan-Meier survival analysis, and stratified Cox proportional hazard modelling.
Results. This study includes data from 575 blood product recipients. One half of the recipients died within the first year of transfusion and the median time to death was 1.1 years. Survival rates at 5, 10, 15, 20, and 25 years after transfusion were 32%, 22%, 15%, 12%, and 9%, respectively. Survival rates varied with age at transfusion and type of component received, but not by gender. Survival after transfusion varied by year of transfusion, with recipients transfused in 1980-1989 having longer post-transfusion survival than those transfused in 2000-2010 (p=0.049). In multivariate models, the type of component transfused, but not the year of transfusion, was a significant predictor of survival among recipients; this effect varied by age.
Discussion. We provide an estimate of survival time from a geographically diverse sample of blood product recipients in the USA. Predictors of post-transfusion survival are numerous and complex, and may include year of transfusion and type of component transfused.
C1 [Dorsey, Kern I. A.; Moritz, Erin D.; Notari, Edward P.; Dodd, Roger Y.] Amer Red Cross, Jerome H Holland Lab Biomed Sci, Rockville, MD 20855 USA.
[Schonberger, Lawrence B.] Ctr Dis Control & Prevent, Natl Ctr Emerging & Zoonot Infect Dis, Div High Consequence Pathogens & Pathol, Atlanta, GA USA.
RP Dodd, RY (reprint author), Amer Red Cross, Jerome H Holland Lab Biomed Sci, 15601 Crabbs Branch Way, Rockville, MD 20855 USA.
EM roger.dodd@redcross.org
FU CJD Foundation
FX The Authors would like to acknowledge the blood centres and regions that
identified and reported both the donors for the CJD look-back
investigation and the recipients involved in this study. The Authors are
also grateful to the CJD Foundation (Florence Kranitz and her
colleagues) for their support in spreading the word about the look-back
investigation. Finally, the Authors would like to thank Fatemeh Musavi
from the American Red Cross for her SAS programming help.
NR 21
TC 1
Z9 1
U1 0
U2 0
PU SIMITI SERVIZI SRL
PI MILAN
PA VIA DESIDERIO 21, MILAN, 20131, ITALY
SN 1723-2007
J9 BLOOD TRANSFUS-ITALY
JI Blood Transf.
PD JAN
PY 2014
VL 12
IS 1
BP 67
EP 72
DI 10.2450/2013.0047-13
PG 6
WC Hematology
SC Hematology
GA AC1OR
UT WOS:000332266400013
PM 24333056
ER
PT J
AU Jere, KC
Esona, MD
Ali, YH
Peenze, I
Roy, S
Bowen, MD
Saeed, IK
Khalafalla, AI
Nyaga, MM
Mphahlele, J
Steele, D
Seheri, ML
AF Jere, Khuzwayo C.
Esona, Mathew D.
Ali, Yahia H.
Peenze, Ina
Roy, Sunando
Bowen, Michael D.
Saeed, Intisar K.
Khalafalla, AbdelMelik I.
Nyaga, Martin M.
Mphahlele, Jeffrey
Steele, Duncan
Seheri, Mapaseka L.
TI Novel NSP1 genotype characterised in an African camel G8P[11] rotavirus
strain
SO INFECTION GENETICS AND EVOLUTION
LA English
DT Article
DE Camel rotavirus; Africa; Whole genome analysis; Rotavirus genotypes
ID GROUP-A ROTAVIRUS; FULL GENOMIC ANALYSIS; MOLECULAR CHARACTERIZATION;
INTERSPECIES TRANSMISSION; PROVIDES EVIDENCE; VP6 GENES; IDENTIFICATION;
G8; CLASSIFICATION; DS-1-LIKE
AB Animal-human interspecies transmission is thought to play a significant role in influencing rotavirus strain diversity in humans. Proving this concept requires a better understanding of the complete genetic constellation of rotaviruses circulating in various animal species. However, very few whole genomes of animal rotaviruses, especially in developing countries, are available. In this study, complete genetic configuration of the first African camel rotavirus strain (RVA/Camel-wt/SDN/MRC-DPRU447/2002/G8P[11]) was assigned a unique G8-P[11]-I2-R2-C2-M2-A18-N2-T6-E2-H3 genotype constellation that has not been reported in other ruminants. It contained a novel NSP1 genotype (genotype A18). The evolutionary dynamics of the genome segments of strain MRC-DPRU447 were rather complex compared to those found in other camelids. Its genome segments 1, 3, 7-10 were closely related (>93% nucleotide identity) to those of human-animal reassortant strains like RVA/Human-tc/ITA/PA169/1988/G6P[14] and RVA/ Human-wt/HUN/Hun5/1997/G6P[14], segments 4, 6 and 11 shared common ancestry (>95% nucleotide identity) with bovine rotaviruses like strains RVA/Cow-wt/CHN/DQ-75/2008/G10P[11] and RVA/Cowwt/ KOR/KJ19-2/XXXX/G6P[7], whereas segment 2 was closely related (94% nucleotide identity) to guanaco rotavirus strain RVA/Guanaco-wt/ARG/Rio_Negro/1998/G8P[1]. Its genetic backbone consisted of DS-1-like, AU-1-like, artiodactyl-like and a novel A18 genotype. This suggests that strain MRC-DPRU447 potentially emerged through multiple reassortment events between several mammalian rotaviruses of at least two genogroups or simply strain MRC-DPRU447 display a unique progenitor genotypes. Close relationship between some of the genome segments of strain MRC-DPRU447 to human rotaviruses suggests previous occurrence of reassortment processes combined with interspecies transmission between humans and camels. The whole genome data for strain MRC-DPRU447 adds to the much needed animal rotavirus data from Africa which is limited at the moment. (C) 2013 Elsevier B.V. All rights reserved.
C1 [Jere, Khuzwayo C.; Esona, Mathew D.; Peenze, Ina; Nyaga, Martin M.; Mphahlele, Jeffrey; Steele, Duncan; Seheri, Mapaseka L.] Univ Limpopo, NHLS Dr George Mukhari Tertiary Lab, MRC, Diarrhoeal Pathogens Res Unit,Dept Virol, Pretoria, South Africa.
[Esona, Mathew D.; Roy, Sunando; Bowen, Michael D.] CDC, Gastroenteritis & Resp Viruses Lab Branch, Div Viral Dis, NCIRD, Atlanta, GA 30333 USA.
[Ali, Yahia H.; Saeed, Intisar K.] Dept Virol, Cent Vet Res Lab, Khartoum, Sudan.
[Khalafalla, AbdelMelik I.] Univ Khartoum, Dept Microbiol, Fac Vet Med, Shambat 13314, Khartoum North, Sudan.
[Jere, Khuzwayo C.] Univ Liverpool, Inst Infect & Global Hlth, Dept Clin Infect Microbiol & Immunol, Liverpool L69 3BX, Merseyside, England.
RP Seheri, ML (reprint author), Univ Limpopo, Dept Virol, POB 173, ZA-0204 Medunsa, South Africa.
EM mapaseka.seheri@ul.ac.za
OI Khalafalla, Abdelmalik/0000-0001-9156-1361; Jere,
Khuzwayo/0000-0003-3376-8529
FU Medical Research Council of South Africa
FX We thank Mr. Andrew M. Musyoki and Mr. Lorens L. Maake for critical
reading of the manuscript; and Miss. Leah Nemarude for technical
support. This work was financially supported by the Medical Research
Council of South Africa.
NR 34
TC 19
Z9 20
U1 0
U2 3
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1567-1348
EI 1567-7257
J9 INFECT GENET EVOL
JI Infect. Genet. Evol.
PD JAN
PY 2014
VL 21
BP 58
EP 66
DI 10.1016/j.meegid.2013.10.002
PG 9
WC Infectious Diseases
SC Infectious Diseases
GA AC1RN
UT WOS:000332273800006
PM 24184096
ER
PT J
AU Mijatovic-Rustempasic, S
Teel, EN
Kerin, TK
Hull, JJ
Roy, S
Weinberg, GA
Payne, DC
Parashar, UD
Gentsch, JR
Bowen, MD
AF Mijatovic-Rustempasic, Slavica
Teel, Elizabeth N.
Kerin, Tara K.
Hull, Jennifer J.
Roy, Sunando
Weinberg, Geoffrey A.
Payne, Daniel C.
Parashar, Umesh D.
Gentsch, Jon R.
Bowen, Michael D.
TI Genetic analysis of G12P[8] rotaviruses detected in the largest US G12
genotype outbreak on record
SO INFECTION GENETICS AND EVOLUTION
LA English
DT Article
DE Rotavirus; USA; VP7 protein; VP4 protein; VP8*; Vaccine
ID GROUP-A ROTAVIRUS; UNITED-STATES; PHYLOGENETIC ANALYSIS; STRAIN
SURVEILLANCE; TRYPSIN ENHANCEMENT; BINDING DOMAIN; GLOBAL SPREAD;
CHILDREN; VP4; PROTEIN
AB In 2006-07, 77 cases of gastroenteritis in Rochester, NY, USA were associated with rotavirus genotype G12P[8]. Sequence analysis identified a high degree of genetic relatedness among the VP7 and VP4 genes of the Rochester G12P[8] strains and between these strains and currently circulating human G12P[8] strains. Out of 77 samples, two and seven unique nucleotide sequences were identified for VP7 and VP4 genes, respectively. Rochester strain VP7 genes were found to occupy the G12-III lineage and VP4 genes clustered within the P[8]-3 lineage. Six strains contained non-synonymous nucleotide substitutions that produced amino acid changes at 6 sites in the VP8/region of the VP4 gene. Two sites (amino acids 242 and 246) were located in or near a described trypsin cleavage site. Selection analyses identified one positively selected VP7 site (107) and strong purifying selection at 58 sites within the VP7 gene as well as 2 of the 6 variant sites (79 and 218) in VP4. Published by Elsevier B.V.
C1 [Mijatovic-Rustempasic, Slavica; Teel, Elizabeth N.; Kerin, Tara K.; Hull, Jennifer J.; Roy, Sunando; Payne, Daniel C.; Parashar, Umesh D.; Gentsch, Jon R.; Bowen, Michael D.] Ctr Dis Control & Prevent, Div Viral Dis, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
[Weinberg, Geoffrey A.] Univ Rochester, Sch Med & Dent, Dept Pediat, Rochester, NY 14642 USA.
RP Bowen, MD (reprint author), Ctr Dis Control & Prevent, Gastroenteritis & Resp Viruses Lab Branch, DVD, NCIRD, 1600 Clifton Rd NE,Mailstop G04, Atlanta, GA 30333 USA.
EM mkb6@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 47
TC 14
Z9 15
U1 0
U2 2
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1567-1348
EI 1567-7257
J9 INFECT GENET EVOL
JI Infect. Genet. Evol.
PD JAN
PY 2014
VL 21
BP 214
EP 219
DI 10.1016/j.meegid.2013.11.004
PG 6
WC Infectious Diseases
SC Infectious Diseases
GA AC1RN
UT WOS:000332273800024
PM 24270016
ER
PT J
AU Vaughan, G
Rossi, LMG
Forbi, JC
de Paula, VS
Purdy, MA
Xia, GL
Khudyakov, YE
AF Vaughan, Gilberto
Goncalves Rossi, Livia Maria
Forbi, Joseph C.
de Paula, Vanessa S.
Purdy, Michael A.
Xia, Guoliang
Khudyakov, Yury E.
TI Hepatitis A virus: Host interactions, molecular epidemiology and
evolution
SO INFECTION GENETICS AND EVOLUTION
LA English
DT Review
DE Hepatitis A virus; Molecular epidemiology; Genetic relatedness;
Genotype; Molecular evolution; Host factors
ID INJECTING DRUG-USERS; DOUBLE-STRANDED-RNA; RIO-DE-JANEIRO;
IRES-DEPENDENT TRANSLATION; INNATE ANTIVIRAL RESPONSES;
TRACT-BINDING-PROTEIN; ACUTE VIRAL-HEPATITIS; TOLL-LIKE RECEPTOR-3;
CHILD-CARE CENTER; NF-KAPPA-B
AB Infection with hepatitis A virus (HAV) is the commonest viral cause of liver disease and presents an important public health problem worldwide. Several unique HAV properties and molecular mechanisms of its interaction with host were recently discovered and should aid in clarifying the pathogenesis of hepatitis A. Genetic characterization of HAV strains have resulted in the identification of different genotypes and subtypes, which exhibit a characteristic worldwide distribution. Shifts in HAV endemicity occurring in different parts of the world, introduction of genetically diverse strains from geographically distant regions, genotype displacement observed in some countries and population expansion detected in the last decades of the 20th century using phylogenetic analysis are important factors contributing to the complex dynamics of HAV infections worldwide. Strong selection pressures, some of which, like usage of deoptimized codons, are unique to HAV, limit genetic variability of the virus. Analysis of subgenomic regions has been proven useful for outbreak investigations. However, sharing short sequences among epidemiologically unrelated strains indicates that specific identification of HAV strains for molecular surveillance can be achieved only using whole-genome sequences. Here, we present up-to-date information on the HAV molecular epidemiology and evolution, and highlight the most relevant features of the HAV-host interactions. Published by Elsevier B.V.
C1 [Vaughan, Gilberto; Goncalves Rossi, Livia Maria; Forbi, Joseph C.; Purdy, Michael A.; Xia, Guoliang; Khudyakov, Yury E.] Ctr Dis Control & Prevent, Div Viral Hepatitis, Atlanta, GA 30333 USA.
[de Paula, Vanessa S.] Fiocruz MS, Inst Oswaldo Cruz, Lab Viral Hepatitis, BR-21045900 Rio De Janeiro, Brazil.
RP Vaughan, G (reprint author), Ctr Dis Control & Prevent, Mol Epidemiol & Bioinformat Lab, Div Viral Hepatitis, 1600 Clifton Rd,M-S A-33, Atlanta, GA 30333 USA.
EM GVaughan@cdc.gov
NR 240
TC 23
Z9 25
U1 3
U2 22
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1567-1348
EI 1567-7257
J9 INFECT GENET EVOL
JI Infect. Genet. Evol.
PD JAN
PY 2014
VL 21
BP 227
EP 243
DI 10.1016/j.meegid.2013.10.023
PG 17
WC Infectious Diseases
SC Infectious Diseases
GA AC1RN
UT WOS:000332273800026
PM 24200587
ER
PT J
AU Cui, AL
Zhu, Z
Chen, M
Zheng, HY
Liu, L
Wang, Y
Ma, Y
Wang, CY
Fang, XQ
Li, P
Guan, RH
Wang, S
Zhou, JH
Zheng, L
Gao, H
Ding, ZR
Li, LQ
Bo, F
Sun, ZD
Zhang, ZY
Feng, DX
He, JL
Chen, H
Jin, L
Rota, PA
Xu, WB
AF Cui, Aili
Zhu, Zhen
Chen, Meng
Zheng, Huanying
Liu, Leng
Wang, Yan
Ma, Yan
Wang, Changyin
Fang, Xueqiang
Li, Ping
Guan, Ronghui
Wang, Shuang
Zhou, Jianhui
Zheng, Lei
Gao, Hui
Ding, Zhengrong
Li, Liqun
Bo, Fang
Sun, Zhaodan
Zhang, Zhenying
Feng, Daxing
He, Jilan
Chen, Hui
Jin, Li
Rota, Paul A.
Xu, Wenbo
TI Epidemiologic and genetic characteristics of mumps viruses isolated in
China from 1995 to 2010
SO INFECTION GENETICS AND EVOLUTION
LA English
DT Article
DE Mumps virus; Epidemiology; Genetic characteristics
ID SH GENE; GENOTYPES; SEQUENCE; STRAINS; JAPAN
AB The epidemiologic and genetic characteristics of mumps viruses detected in China from 1995 to 2010 were analyzed in this study. Mumps remains endemic in China with a high overall incidence rate. The incidence of mumps in Western China was higher than that in other regions of the country. Each year, most of mumps cases occurred between April and July, but a small peak also occurred in November and December. Mumps cases primarily affected the under 15 year old age group. Virologic data demonstrated that genotype F was the predominant circulating genotype throughout China for at least 15 years and no other genotype was detected between 1995 and 2010. Analysis of sequence data from the small hydrophobic (SH) gene indicated that multiple transmission chains of genotype F were found in various provinces of China, with no apparent chronologic and geographic restriction. This is the first report describing the epidemiology of mumps and genetic characterization of mumps viruses at the national level in China. (C) 2013 Elsevier B. V. All rights reserved.
C1 [Cui, Aili; Zhu, Zhen; Xu, Wenbo] China Ctr Dis Control & Prevent, Natl Inst Viral Dis Control & Prevent, Beijing 102206, Peoples R China.
[Chen, Meng] Beijing Prov Ctr Dis Control & Prevent, Beijing 100013, Peoples R China.
[Zheng, Huanying; Liu, Leng] Guangdong Prov Ctr Dis Control & Prevent, Guangzhou 511430, Peoples R China.
[Wang, Yan; Ma, Yan] Liaoning Prov Ctr Dis Control & Prevent, Shenyang 110005, Peoples R China.
[Wang, Changyin; Fang, Xueqiang] Shandong Prov Ctr Dis Control & Prevent, Jinan 250014, Peoples R China.
[Li, Ping; Guan, Ronghui] Shannxi Prov Ctr Dis Control & Prevent, Xian 710054, Peoples R China.
[Wang, Shuang; Zhou, Jianhui] Jilin Prov Ctr Dis Control & Prevent, Changchun 130062, Peoples R China.
[Zheng, Lei; Gao, Hui] Shanxi Prov Ctr Dis Control & Prevent, Taiyuan 030012, Peoples R China.
[Ding, Zhengrong; Li, Liqun] Yunnan Prov Ctr Dis Control & Prevent, Kunming 650022, Peoples R China.
[Bo, Fang; Sun, Zhaodan] Heilongjiang Prov Ctr Dis Control & Prevent, Haerbin 150030, Peoples R China.
[Zhang, Zhenying; Feng, Daxing] Henan Prov Ctr Dis Control & Prevent, Zhengzhou 450016, Peoples R China.
[He, Jilan] Sichuan Prov Ctr Dis Control & Prevent, Chengdu 610041, Peoples R China.
[Chen, Hui] Ningxia Prov Ctr Dis Control & Prevent, Yinchuan 750004, Peoples R China.
[Jin, Li] Publ Hlth England, Virus Reference Dept, London NW9 5EQ, England.
[Rota, Paul A.] Ctr Dis Control & Prevent, Div Viral Dis, Atlanta, GA 30333 USA.
RP Xu, WB (reprint author), 155 Chang Bai Rd, Beijing 102206, Peoples R China.
EM wenbo_xu1@aliyun.com
FU National Natural Science Foundation of China [81102170]; National
Infectious Disease Surveillance Program of the Ministry of Science and
Technology of the People's Republic of China [2012ZX10004201-003,
2013ZX10004202]
FX This work was partially supported by the National Natural Science
Foundation of China (Project No. 81102170), the National Infectious
Disease Surveillance Program of the Ministry of Science and Technology
of the People's Republic of China (2012ZX10004201-003 and
2013ZX10004202).
NR 25
TC 6
Z9 6
U1 1
U2 4
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1567-1348
EI 1567-7257
J9 INFECT GENET EVOL
JI Infect. Genet. Evol.
PD JAN
PY 2014
VL 21
BP 384
EP 390
DI 10.1016/j.meegid.2013.12.005
PG 7
WC Infectious Diseases
SC Infectious Diseases
GA AC1RN
UT WOS:000332273800044
PM 24355245
ER
PT J
AU Onufrak, SJ
Park, S
Sharkey, JR
Sherry, B
AF Onufrak, Stephen J.
Park, Sohyun
Sharkey, Joseph R.
Sherry, Bettylou
TI The relationship of perceptions of tap water safety with intake of
sugar- sweetened beverages and plain water among US adults
SO PUBLIC HEALTH NUTRITION
LA English
DT Article
DE Drinking water; Beverages; Perceptions
ID BOTTLED WATER; MINORITY CHILDREN; BODY-WEIGHT; CONSUMPTION; HEALTH;
ADOLESCENTS; LATINO
AB Objective Research is limited on whether mistrust of tap water discourages plain water intake and leads to a greater intake of sugar-sweetened beverages (SSB). The objective of the present study was to examine demographic differences in perceptions of tap water safety and determine if these perceptions are associated with intake of SSB and plain water.
Design The study examined perceptions of tap water safety and their cross-sectional association with intake of SSB and plain water. Racial/ethnic differences in the associations of tap water perceptions with SSB and plain water intake were also examined.
Setting Nationally weighted data from the 2010 HealthStyles Survey (n 4184).
Subjects US adults aged 18 years.
Results Overall, 130 % of participants disagreed that their local tap water was safe to drink and 264 % of participants agreed that bottled water was safer than tap water. Both mistrust of tap water safety and favouring bottled water differed by region, age, race/ethnicity, income and education. The associations of tap water mistrust with intake of SSB and plain water were modified by race/ethnicity (P < 005). Non-white racial/ethnic groups who disagreed that their local tap water was safe to drink were more likely to report low intake of plain water. The odds of consuming 1 SSB/d among Hispanics who mistrusted their local tap water was twice that of Hispanics who did not (OR = 20; 95 % CI 12, 33).
Conclusions Public health efforts to promote healthy beverages should recognize the potential impact of tap water perceptions on water and SSB intake among minority populations.
C1 [Onufrak, Stephen J.; Park, Sohyun; Sherry, Bettylou] Ctr Dis Control & Prevent, Div Nutr Phys Act & Obes, Obes Prevent & Control Branch, Atlanta, GA 30341 USA.
[Sharkey, Joseph R.] Texas A&M Univ, Sch Rural Publ Hlth, College Stn, TX USA.
RP Onufrak, SJ (reprint author), Ctr Dis Control & Prevent, Div Nutr Phys Act & Obes, Obes Prevent & Control Branch, 4770 Buford Highway NE,MS K-26, Atlanta, GA 30341 USA.
EM seo5@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 21
TC 8
Z9 8
U1 2
U2 9
PU CAMBRIDGE UNIV PRESS
PI CAMBRIDGE
PA EDINBURGH BLDG, SHAFTESBURY RD, CB2 8RU CAMBRIDGE, ENGLAND
SN 1368-9800
EI 1475-2727
J9 PUBLIC HEALTH NUTR
JI Public Health Nutr.
PD JAN
PY 2014
VL 17
IS 1
BP 179
EP 185
DI 10.1017/S1368980012004600
PG 7
WC Public, Environmental & Occupational Health; Nutrition & Dietetics
SC Public, Environmental & Occupational Health; Nutrition & Dietetics
GA AC2YX
UT WOS:000332383300022
PM 23098620
ER
PT J
AU Boland, TA
McGuone, D
Jindal, J
Rocha, M
Cumming, M
Rupprecht, CE
Barbosa, TFS
Oliveira, RD
Chu, CJ
Cole, AJ
Kotait, I
Kuzmina, NA
Yager, PA
Kuzmin, IV
Hedley-Whyte, ET
Brown, CM
Rosenthal, ES
AF Boland, Torrey A.
McGuone, Declan
Jindal, Jenelle
Rocha, Marcelo
Cumming, Melissa
Rupprecht, Charles E.
Souza Barbosa, Taciana Fernandes
Oliveira, Rafael de Novaes
Chu, Catherine J.
Cole, Andrew J.
Kotait, Ivanete
Kuzmina, Natalia A.
Yager, Pamela A.
Kuzmin, Ivan V.
Hedley-Whyte, E. Tessa
Brown, Catherine M.
Rosenthal, Eric S.
TI Phylogenetic and Epidemiologic Evidence of Multiyear Incubation in Human
Rabies
SO ANNALS OF NEUROLOGY
LA English
DT Article
ID UNITED-STATES
AB Eight years after emigrating from Brazil, an otherwise healthy man developed rabies. An exposure prior to immigration was reported. Genetic analysis revealed a canine rabies virus variant found only in the patient's home country, and the patient had not traveled internationally since immigrating to the United States. We describe how epidemiological, phylogenetic, and viral sequencing data provided confirmation that rabies encephalomyelitis may present after a long, multiyear incubation period, a consideration that previously has been hypothesized without the ability to exclude a more recent exposure. Accordingly, rabies should be considered in the diagnosis of any acute encephalitis, myelitis, or encephalomyelitis.
C1 [Boland, Torrey A.] Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA.
[McGuone, Declan; Hedley-Whyte, E. Tessa] Harvard Univ, Massachusetts Gen Hosp, Sch Med, CS Kubik Lab Neuropathol,Dept Pathol, Boston, MA USA.
[Jindal, Jenelle; Rocha, Marcelo; Chu, Catherine J.; Cole, Andrew J.; Rosenthal, Eric S.] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Neurol, Boston, MA USA.
[Cumming, Melissa; Brown, Catherine M.] Hinton State Lab, Massachusetts Dept Publ Hlth, Jamaica Plain, MA USA.
[Rupprecht, Charles E.] Global Alliance Rabies Control, Manhattan, KS USA.
[Souza Barbosa, Taciana Fernandes] Evandro Chagas Inst, Para, Brazil.
[Oliveira, Rafael de Novaes; Kotait, Ivanete] Inst Pasteur, Sao Paulo, Brazil.
[Kuzmina, Natalia A.; Yager, Pamela A.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Kuzmin, Ivan V.] Aravan LLC, Lilburn, GA USA.
RP Boland, TA (reprint author), Rush Univ, Med Ctr, Dept Neurol Sci, 1725 W Harrison St,Suite 1106, Chicago, IL 60612 USA.
EM torrey_boland@rush.edu
OI Rosenthal, Eric/0000-0003-3900-356X
FU NIH National Institute of Neurological Diseases and Stroke
FX A.J.C.: consultancy, Clarus Ventures, Concert Pharmaceuticals, Sage
Pharmaceuticals, Eisai Pharmaceuticals; grants/grants pending, NIH
National Institute of Neurological Diseases and Stroke. P. A. Y.:
royalties, EMD Millipore (Chemicon International).
NR 14
TC 2
Z9 2
U1 0
U2 5
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0364-5134
EI 1531-8249
J9 ANN NEUROL
JI Ann. Neurol.
PD JAN
PY 2014
VL 75
IS 1
BP 155
EP 160
DI 10.1002/ana.24016
PG 6
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA AA3WQ
UT WOS:000331026300017
PM 24038455
ER
PT J
AU Chiu, CH
Noe, RS
Martin, JP
Wolkin, AF
Vagi, SJ
AF Chiu, Cindy H.
Noe, Rebecca S.
Martin, John Paul
Wolkin, Amy F.
Vagi, Sara J.
TI The Use of Community Assessment for Public Health Emergency Response to
Evaluate NWS Warnings
SO BULLETIN OF THE AMERICAN METEOROLOGICAL SOCIETY
LA English
DT Article
C1 [Chiu, Cindy H.] Ctr Dis Control & Prevent, Epidem Intelligence Serv Program, Atlanta, GA 30341 USA.
[Noe, Rebecca S.; Vagi, Sara J.] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Atlanta, GA 30341 USA.
[Martin, John Paul] NOAA, US Dept Commerce, NWS Weather Forecast Off, Bismarck, ND USA.
[Wolkin, Amy F.] Ctr Dis Control & Prevent, Disaster Epidemiol & Response Team, Natl Ctr Environm Hlth, Atlanta, GA 30341 USA.
RP Chiu, CH (reprint author), Ctr Dis Control & Prevent, Epidem Intelligence Serv Program, 4770 Buford Hwy,Mississippi F-60, Atlanta, GA 30341 USA.
EM cchiu@cdc.gov
OI Chiu, Cindy H/0000-0003-2226-2776
FU Intramural CDC HHS [CC999999]
NR 0
TC 0
Z9 0
U1 0
U2 3
PU AMER METEOROLOGICAL SOC
PI BOSTON
PA 45 BEACON ST, BOSTON, MA 02108-3693 USA
SN 0003-0007
EI 1520-0477
J9 B AM METEOROL SOC
JI Bull. Amer. Meteorol. Soc.
PD JAN
PY 2014
VL 95
IS 1
BP 18
EP 21
DI 10.1175/BAMS-D-12-00123.1
PG 4
WC Meteorology & Atmospheric Sciences
SC Meteorology & Atmospheric Sciences
GA AB8NL
UT WOS:000332047200005
PM 27293241
ER
PT J
AU Welcome, DE
Dong, RG
Xu, XYS
Warren, C
McDowell, TW
AF Welcome, Daniel E.
Dong, Ren G.
Xu, Xueyan S.
Warren, Christopher
McDowell, Thomas W.
TI The effects of vibration-reducing gloves on finger vibration
SO INTERNATIONAL JOURNAL OF INDUSTRIAL ERGONOMICS
LA English
DT Article
DE Finger vibration; Anti-vibration glove; Vibration-reducing glove;
Hand-arm vibration; Hand-transmitted vibration
ID NONCONTACT MEASUREMENT; ISOLATION PERFORMANCE; ANTIVIBRATION GLOVES;
MECHANICAL IMPEDANCE; HAND-VIBRATION; ARM; TRANSMISSIBILITY; HAZARDS;
HAMMER
AB Vibration-reducing (VR) gloves have been used to reduce the hand-transmitted vibration exposures from machines and powered hand tools but their effectiveness remains unclear, especially for finger protection. The objectives of this study are to determine whether VR gloves can attenuate the vibration transmitted to the fingers and to enhance the understanding of the mechanisms of how these gloves work. Seven adult male subjects participated in the experiment. The fixed factors evaluated include hand force (four levels), glove condition (gel-filled, air bladder, no gloves), and location of the finger vibration measurement: A 3-D laser vibrometer was used to measure the vibrations on the fingers with and without wearing a glove on a 3-D hand-arm vibration test system. This study finds that the effect of VR gloves on the finger vibration depends on not only the gloves but also their influence on the distribution of the finger contact stiffness and the grip effort. As a result, the gloves increase the vibration in the fingertip area but marginally reduce the vibration in the proximal area at some frequencies below 100 Hz. On average, the gloves reduce the vibration of the entire fingers by less than 3% at frequencies below 80 Hz but increase at frequencies from 80 to 400 Hz. At higher frequencies, the gel-filled glove is more effective at reducing the finger vibration than the air bladder-filled glove. The implications of these findings are discussed.
Relevance to industry: Prolonged, intensive exposure to hand-transmitted vibration can cause hand-arm vibration syndrome. Vibration-reducing gloves have been used as an alternative approach to reduce the vibration exposure. However, their effectiveness for reducing finger-transmitted vibrations remains unclear. This study enhanced the understanding of the glove effects on finger vibration and provided useful information on the effectiveness of typical VR gloves at reducing the vibration transmitted to the fingers. The new results and knowledge can be used to help select appropriate gloves for the operations of powered hand tools, to help perform risk assessment of the vibration exposure, and to help design better VR gloves. Published by Elsevier B.V.
C1 [Welcome, Daniel E.; Dong, Ren G.; Xu, Xueyan S.; Warren, Christopher; McDowell, Thomas W.] NIOSH, Engn & Control Technol Branch, HELD, CDC, Morgantown, WV 26505 USA.
RP Dong, RG (reprint author), NIOSH, Engn & Control Technol Branch, HELD, CDC, MS L-2027,1095 Willowdale Rd, Morgantown, WV 26505 USA.
EM rkd6@cdc.gov
OI McDowell, Thomas/0000-0002-2416-2210
FU Intramural CDC HHS [CC999999]
NR 36
TC 11
Z9 12
U1 1
U2 16
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0169-8141
EI 1872-8219
J9 INT J IND ERGONOM
JI Int. J. Ind. Ergon.
PD JAN
PY 2014
VL 44
IS 1
BP 45
EP 59
DI 10.1016/j.ergon.2013.10.003
PG 15
WC Engineering, Industrial; Ergonomics
SC Engineering
GA AC2SN
UT WOS:000332354400007
PM 26543297
ER
PT J
AU Sabogal, RI
Medlin, E
Aquino, G
Gelting, RJ
AF Sabogal, Raquel I.
Medlin, Elizabeth
Aquino, Gonzalo
Gelting, Richard J.
TI Sustainability of water, sanitation and hygiene interventions in Central
America
SO JOURNAL OF WATER SANITATION AND HYGIENE FOR DEVELOPMENT
LA English
DT Article
DE Central America; evaluation; hygiene promotion; sanitation;
sustainability; water
AB The American Red Cross and U. S. Centers for Disease Control and Prevention collaborated on a sustainability evaluation of post-hurricane water, sanitation and hygiene (WASH) interventions in Central America. In 2006 and 2009, we revisited six study areas in rural El Salvador, Guatemala, Honduras and Nicaragua to assess sustainability of WASH interventions finalized in 2002, after 1998's Hurricane Mitch. We used surveys to collect data, calculate indicators and identify factors that influence sustainability. Regional sustainability indicator results showed there was a statistically significant decline in access to water. The presence of sanitation facilities had not changed since the beginning of the project; however, maintenance and use of latrines declined but continued to meet the goal of 75% use after 7 years. The hygiene indicator, hand washing, initially declined and then increased. Declines in water access were due to operational problems related to storm events and population changes. Sanitation facilities were still present and sometimes used even though they reached or surpassed their original design life. Changes in hygiene practices appeared related to ongoing hygiene promotion from outside organizations. These results provide useful input for making WASH programs more sustainable and informing future, more in-depth research into factors influencing sustainability.
C1 [Sabogal, Raquel I.; Medlin, Elizabeth; Gelting, Richard J.] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Div Emergency & Environm Hlth Serv, Chamblee, GA 30341 USA.
[Aquino, Gonzalo] Amer Red Cross, Water & Sanitat Delegate Latin Amer & Caribbean R, Qual & Learning Unit, Panama City, Panama.
RP Sabogal, RI (reprint author), Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Div Emergency & Environm Hlth Serv, 4770 Buford Highway NE, Chamblee, GA 30341 USA.
EM rsabogal@cdc.gov
FU American Red Cross, Red Cross National Societies water and sanitation
delegates
FX The authors would like to thank the American Red Cross, Red Cross
National Societies water and sanitation delegates, and all community
members who participated in our study. Their support ensured our success
with this study. American Red Cross (Sergio Denegri, Mark Toy) and Red
Cross National Societies (El Salvador-Mirna Zelaya, Salvador Molina,
Adan Rivas; Guatemala-Maria Teresa Estrada, Adolfo Saguil; Honduras-Joel
Duron, Jorge Pinel; Nicaragua-Carmen Maria Garcia Bucardo, David
Maxwell, Ramona Caceres). We would also like to thank the additional CDC
investigators who participated in past data collections (Lana Corrales
MPH, Victoria Cuellar MPH, Kristin Delea MPH, Jane Horton MPH, Carolyn
Monteilh PhD).
NR 22
TC 1
Z9 1
U1 2
U2 18
PU IWA PUBLISHING
PI LONDON
PA ALLIANCE HOUSE, 12 CAXTON ST, LONDON SW1H0QS, ENGLAND
SN 2043-9083
J9 J WATER SANIT HYG DE
JI J. Wate Sanit. Hyg. Dev.
PY 2014
VL 4
IS 1
BP 89
EP 99
DI 10.2166/washdev.2013.130
PG 11
WC Water Resources
SC Water Resources
GA AB8XH
UT WOS:000332072800010
PM 26413262
ER
PT J
AU Hubbard, B
Lockhart, G
Gelting, RJ
Bertrand, F
AF Hubbard, Brian
Lockhart, Gabriella
Gelting, Richard J.
Bertrand, Fabienne
TI Development of Haiti's rural water, sanitation and hygiene workforce
SO JOURNAL OF WATER SANITATION AND HYGIENE FOR DEVELOPMENT
LA English
DT Article
DE cholera; Haiti; sanitation and hygiene; water quality; water; workforce
development
AB In 2009 the Haitian Directorate of Potable Water and Sanitation (DINEPA) identified an inadequately trained and under-staffed rural workforce as one of their main institutional challenges. Plans to address this challenge were impacted by the devastating earthquake of January 12, 2010 and the cholera outbreak of October 2010, both of which further complicated Haiti's already poor water and sanitation conditions. Recognizing the importance of DINEPA's institutional priorities, donor and technical assistance groups provided needed support to improve the country's conditions and build the rural water and sanitation workforce. This report describes how DINEPA and the US Centers for Disease Control and Prevention (CDC) collaborated to design and implement a training program for 264 potable water and sanitation technicians for rural areas. The paper also describes the initial field activities of the newly trained technicians and the immediate impact of their work in the rural water, sanitation and hygiene sector.
C1 [Hubbard, Brian] US Ctr Dis Control & Prevent, Environm Hlth Serv Branch, Natl Ctr Environm Hlth, Dept Hlth & Human Serv, Atlanta, GA 30341 USA.
[Lockhart, Gabriella] US Ctr Dis Control & Prevent, Environm Hlth Serv Branch, Natl Ctr Environm Hlth, Dept Hlth & Human Serv, Brookline, MA 02445 USA.
[Gelting, Richard J.] US Ctr Dis Control & Prevent, Hlth Syst Reconstruct Team, Emergency Response & Recovery Branch, Div Global Hlth Protect,Ctr Global Hlth,Dept Hlth, Atlanta, GA 30329 USA.
[Bertrand, Fabienne] Natl Directorate Potable Water & Sanitat, Petion Ville, Haiti.
RP Hubbard, B (reprint author), US Ctr Dis Control & Prevent, Environm Hlth Serv Branch, Natl Ctr Environm Hlth, Dept Hlth & Human Serv, 4770 Buford Highway,MS F-58, Atlanta, GA 30341 USA.
EM bnh5@cdc.gov
FU Inter-American Development Bank (IADB); World Bank
FX The authors would like to acknowledge the contributions of the
Inter-American Development Bank (IADB), and the World Bank for their
financial and technical support of the TEPAC program. Additionally, the
authors would like to thank Dr Thomas Handzel for his leadership and
direction of WASH activities in Haiti, and Kitty Middleton, Molly
Patrick and Martin Fogl for their technical, management and
communication support with stakeholders in the water and sanitation
sector in Haiti.
NR 6
TC 1
Z9 1
U1 7
U2 29
PU IWA PUBLISHING
PI LONDON
PA ALLIANCE HOUSE, 12 CAXTON ST, LONDON SW1H0QS, ENGLAND
SN 2043-9083
J9 J WATER SANIT HYG DE
JI J. Wate Sanit. Hyg. Dev.
PY 2014
VL 4
IS 1
BP 159
EP 163
DI 10.2166/washdev.2013.089
PG 5
WC Water Resources
SC Water Resources
GA AB8XH
UT WOS:000332072800017
ER
PT J
AU Lockhart, G
Oswald, WE
Hubbard, B
Medlin, E
Gelting, RJ
AF Lockhart, Gabriella
Oswald, William E.
Hubbard, Brian
Medlin, Elizabeth
Gelting, Richard J.
TI Development of indicators for measuring outcomes of water safety plans
SO JOURNAL OF WATER SANITATION AND HYGIENE FOR DEVELOPMENT
LA English
DT Article
DE drinking water; evaluation; indicators; outcomes; water safety plans
ID FRAMEWORK
AB Water safety plans (WSPs) are endorsed by the World Health Organization as the most effective method of protecting a water supply. With the increase in WSPs worldwide, several valuable resources have been developed to assist practitioners in the implementation of WSPs, yet there is still a need for a practical and standardized method of evaluating WSP effectiveness. In 2012, the Centers for Disease Control and Prevention (CDC) published a conceptual framework for the evaluation of WSPs, presenting four key outcomes of the WSP process: institutional, operational, financial and policy change. In this paper, we seek to operationalize this conceptual framework by providing a set of simple and practical indicators for assessing WSP outcomes. Using CDC's WSP framework as a foundation and incorporating various existing performance monitoring indicators for water utilities, we developed a set of approximately 25 indicators of institutional, operational, financial and policy change within the WSP context. These outcome indicators hold great potential for the continued implementation and expansion of WSPs worldwide. Having a defined framework for evaluating a WSP's effectiveness, along with a set of measurable indicators by which to carry out that evaluation, will help implementers assess key WSP outcomes internally, as well as benchmark their progress against other WSPs in their region and globally.
C1 [Lockhart, Gabriella; Oswald, William E.; Hubbard, Brian; Medlin, Elizabeth; Gelting, Richard J.] US Ctr Dis Control & Prevent, Water Sanitat & Hyg Team, Environm Hlth Serv Branch, Natl Ctr Environm Hlth,Dept Hlth & Human Serv, Atlanta, GA USA.
RP Gelting, RJ (reprint author), 4770 Buford Highway NE,MS F-57, Atlanta, GA 30341 USA.
EM rgelting@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 16
TC 2
Z9 2
U1 0
U2 6
PU IWA PUBLISHING
PI LONDON
PA ALLIANCE HOUSE, 12 CAXTON ST, LONDON SW1H0QS, ENGLAND
SN 2043-9083
J9 J WATER SANIT HYG DE
JI J. Wate Sanit. Hyg. Dev.
PY 2014
VL 4
IS 1
BP 171
EP 181
DI 10.2166/washdev.2013.159
PG 11
WC Water Resources
SC Water Resources
GA AB8XH
UT WOS:000332072800019
PM 26361540
ER
PT J
AU Marienau, KJ
Cramer, EH
Coleman, MS
Marano, N
Cetron, MS
AF Marienau, Karen J.
Cramer, Elaine H.
Coleman, Margaret S.
Marano, Nina
Cetron, Martin S.
TI Flight related tuberculosis contact investigations in the United States:
Comparative risk and economic analysis of alternate protocols
SO TRAVEL MEDICINE AND INFECTIOUS DISEASE
LA English
DT Article
DE Tuberculosis; TB; Air travel; Contact investigation; Transmission risk;
Cost-benefit analysis
ID MYCOBACTERIUM-TUBERCULOSIS; AIR-TRAVEL; INFECTIOUS TUBERCULOSIS;
TRANSMISSION; AIRPLANE; EXPOSURE; HEALTH
AB Background: In-flight transmission risk of Mycobacterium tuberculosis is not well defined, although studies suggest it is low. The impact of flight-related tuberculosis (TB) contact investigations (TBCIs) on TB prevention and control is not well established, and they compete for resources with activities with established benefits. We sought to determine the risks and cost benefits of using more restrictive criteria in comparison to the Centers for Disease Control and Prevention (CDC) 2008 protocol for TBCIs.
Methods: The risk-benefits of a modified CDC protocol were analyzed in comparison to the 2008 CDC protocol using data from flight-related TBCIs conducted in the United States from 2007 through 2009. We predicted the numbers and characteristics of case-travelers that would be identified using each protocol's criteria, and results of the associated passenger-contacts' TB screening tests. The economic analysis compared the costs of TBCIs to avoided costs of TB treatment and mortality using a Return on Investment model.
Results: The estimated in-flight transmission risk using a modified CDC protocol was 1.4%-19% versus 1.1%-24% for the 2008 protocol. Numbers of TBCIs and immediate costs to health departments were reduced by half. Long-term cost benefits were comparable.
Conclusions: CDC's modified protocol appears to be a feasible alternative that will conserve public health resources without jeopardizing the public's health. Published by Elsevier Ltd.
C1 [Marienau, Karen J.; Coleman, Margaret S.; Marano, Nina; Cetron, Martin S.] Ctr Dis Control & Prevent, Natl Ctr Emerging & Zoonot, Div Global Migrat & Quarantine, Atlanta, GA USA.
[Cramer, Elaine H.] SRA Int, Global Hlth Sect, Atlanta, GA USA.
RP Marienau, KJ (reprint author), Suite 2168,7150 Humphrey Dr, Minneapolis, MN 55450 USA.
EM marienauk@yahoo.com
FU National TB Controllers Association
FX Many people, agencies, and organizations collaborated to conduct the TB
contact investigations from which data were drawn for our analyses. We
express our gratitude to the numerous state and local TB program staff;
the many airlines; our Customs and Border Protection partners; and DGMQ
staff, including Quarantine Station staff from across the United States,
as well as Chris Schembri and Krista Kornylo. Without their
contributions our analyses and subsequent policy change would not have
been possible. We also want to thank our colleagues in the CDC Division
of TB Elimination, Thomas Navin and Suzanne Marks, and the National TB
Controllers Association for their consultation and support.
NR 37
TC 3
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U1 1
U2 1
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1477-8939
EI 1873-0442
J9 TRAVEL MED INFECT DI
JI Travel Med. Infect. Dis.
PD JAN-FEB
PY 2014
VL 12
IS 1
BP 54
EP 62
DI 10.1016/j.tmaid.2013.09.007
PG 9
WC Public, Environmental & Occupational Health; Infectious Diseases
SC Public, Environmental & Occupational Health; Infectious Diseases
GA AC0OA
UT WOS:000332193400009
PM 24206902
ER
PT J
AU Coleman, MS
Marienau, KJ
Marano, N
Marks, SM
Cetron, MS
AF Coleman, Margaret S.
Marienau, Karen J.
Marano, Nina
Marks, Suzanne M.
Cetron, Martin S.
TI Economics of United States tuberculosis airline contact investigation
policies: A return on investment analysis
SO TRAVEL MEDICINE AND INFECTIOUS DISEASE
LA English
DT Article
DE Tuberculosis; Return on investment; Contact tracing
ID INFECTION; COSTS; US
AB Background: In 2011, the Centers for Disease Control and Prevention modified its 2008 protocol for flight-related tuberculosis contact investigation initiation. The 2011 Modified protocol was implemented and replaced the 2008 CDC protocol based on comparative epidemiologic and economic analyses; this publication reports the economic analysis results.
Methods: A return on investment model compared relative changes in tuberculosis disease treatment costs resulting from expenditures on tuberculosis contact investigations and latent tuberculosis infection treatment for the 2008 CDC and Modified protocols.
Results: At moderate/high rates of latent tuberculosis infection and tuberculosis disease, positive returns on investment indicated each $1.00 spent on tuberculosis contact investigations and latent tuberculosis treatment resulted in more than $1.00 of savings from reduced tuberculosis disease treatment costs. Low rates of latent tuberculosis infection and tuberculosis disease resulted in negative returns on investment, indicating economic losses from tuberculosis disease treatment costs. There were smaller economic losses at low latent tuberculosis infection and tuberculosis disease rates with the Modified protocol in comparison to the 2008 CDC protocol, while both identified comparable numbers of persons at risk for tuberculosis.
Conclusion: The Modified protocol for conducting flight-related tuberculosis contact investigations represents a better use of resources and protects public health. Published by Elsevier Ltd.
C1 [Coleman, Margaret S.; Marienau, Karen J.; Marano, Nina; Cetron, Martin S.] Ctr Dis Control & Prevent, Div Global Migrat & Quarantine, Atlanta, GA 30333 USA.
[Marks, Suzanne M.] Ctr Dis Control & Prevent, Div TB Eliminat, Atlanta, GA 30333 USA.
RP Coleman, MS (reprint author), Ctr Dis Control & Prevent, Div Global Migrat & Quarantine, 1600 Clifton Rd,Stop E-03, Atlanta, GA 30333 USA.
EM mcoleman@cdc.gov
NR 29
TC 3
Z9 3
U1 0
U2 1
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1477-8939
EI 1873-0442
J9 TRAVEL MED INFECT DI
JI Travel Med. Infect. Dis.
PD JAN-FEB
PY 2014
VL 12
IS 1
BP 63
EP 71
DI 10.1016/j.tmaid.2013.10.016
PG 9
WC Public, Environmental & Occupational Health; Infectious Diseases
SC Public, Environmental & Occupational Health; Infectious Diseases
GA AC0OA
UT WOS:000332193400010
PM 24262643
ER
PT J
AU Leeman, J
Teal, R
Jernigan, J
Reed, JH
Farris, R
Ammerman, A
AF Leeman, Jennifer
Teal, Randall
Jernigan, Jan
Reed, Jenica Huddleston
Farris, Rosanne
Ammerman, Alice
TI What Evidence and Support Do State-Level Public Health Practitioners
Need to Address Obesity Prevention
SO AMERICAN JOURNAL OF HEALTH PROMOTION
LA English
DT Article
DE Obesity Prevention; Evidence-Based Practice; Public Health; Prevention
Research. Manuscript format: research; Research purpose: descriptive;
Study design: qualitative and quantitative survey; Outcome measure:
cognitive; Setting: state/national; Health focus: fitness/physical
activity; nutrition; Strategy: policy; built environment; Target
population: all; Target population circumstances: all
ID PHYSICAL-ACTIVITY; DISSEMINATION; KNOWLEDGE; SETTINGS; GAP
AB Purpose. Obesity has reached epidemic proportions. Public health practitioners are distinctly positioned to promote the environmental changes essential to addressing obesity. The Centers for Disease Control and Prevention (CDC) and other entities provide evidence and technical assistance to support this work, yet little is known about how practitioners use evidence and support as they intervene to prevent obesity. The study's purpose was to describe how practitioners and CDC project officers characterized the obesity prevention task, where practitioners accessed support and evidence, and what approaches to support and evidence they found most useful.
Approach or Design. Mixed-methods, cross-sectional interviews, and survey.
Setting. State-level public health obesity prevention programs.
Participants. Public health practitioners and CDC project officers.
Method. We conducted 10 in-depth interviews with public health practitioners (n = 7) and project officers (n = 3) followed by an online survey completed by 62 practitioners (50% response rate). We applied content analysis to interview data and descriptive statistics to survey data.
Results. Practitioners characterized obesity prevention as uncertain and complex, involving interdependence among actors, multiple levels of activity, an excess of information, and a paucity of evidence. Survey findings provide further detail on the types of evidence and support practitioners used and valued.
Conclusion. We recommend approaches to tailoring evidence and support to the needs of practitioners working on obesity prevention and other complex health problems.
C1 [Leeman, Jennifer] Univ N Carolina, Sch Nursing, Chapel Hill, NC 27510 USA.
[Teal, Randall] Univ N Carolina, Cecil G Sheps Ctr Hlth Serv Res, Chapel Hill, NC 27510 USA.
[Jernigan, Jan] Ctr Dis Control & Prevent, Div Nutr Phys Act & Obes, Atlanta, GA USA.
[Reed, Jenica Huddleston] Deloitte Consulting LLP, Sacramento, CA USA.
[Farris, Rosanne] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Ammerman, Alice] Univ N Carolina, Dept Nutr, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27510 USA.
[Ammerman, Alice] Univ N Carolina, Ctr Hlth Promot & Dis Prevent, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27510 USA.
RP Leeman, J (reprint author), Univ N Carolina, Sch Nursing, Chapel Hill, NC 27510 USA.
EM jleeman@email.unc.edu
FU AHRQ HHS [K12 HS019468]; NIDDK NIH HHS [P30 DK093002]
NR 27
TC 7
Z9 7
U1 0
U2 9
PU AMER JOURNAL HEALTH PROMOTION INC
PI TROY
PA PO BOX 1254, TROY, MI 48099-1254 USA
SN 0890-1171
EI 2168-6602
J9 AM J HEALTH PROMOT
JI Am. J. Health Promot.
PD JAN-FEB
PY 2014
VL 28
IS 3
BP 189
EP 196
DI 10.4278/ajhp.120518-QUAL-266
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AB6JS
UT WOS:000331894900016
PM 23621811
ER
PT J
AU Ioannidis, JPA
Zhou, Y
Chang, CQ
Schully, SD
Khoury, MJ
Freedman, AN
AF Ioannidis, J. P. A.
Zhou, Y.
Chang, C. Q.
Schully, S. D.
Khoury, M. J.
Freedman, A. N.
TI Potential increased risk of cancer from commonly used medications: an
umbrella review of meta-analyses
SO ANNALS OF ONCOLOGY
LA English
DT Review
DE cancer; meta-analysis; pharmacoepidemiology; randomized trials; review
ID RANDOMIZED CONTROLLED-TRIALS; CONVERTING-ENZYME-INHIBITORS;
NECROSIS-FACTOR THERAPY; CLINICAL-TRIALS; RHEUMATOID-ARTHRITIS;
CARDIOVASCULAR-DISEASE; COLORECTAL-CANCER; STATIN THERAPY;
PANCREATIC-CANCER; LDL CHOLESTEROL
AB Several commonly used medications have been associated with increased cancer risk in the literature. Here, we evaluated the strength and consistency of these claims in published meta-analyses. We carried out an umbrella review of 74 meta-analysis articles addressing the association of commonly used medications (antidiabetics, antihyperlipidemics, antihypertensives, antirheumatics, drugs for osteoporosis, and others) with cancer risk where at least one meta-analysis in the medication class included some data from randomized trials. Overall, 51 articles found no statistically significant differences, 13 found some decreased cancer risk, and 11 found some increased risk (one reported both increased and decreased risks). The 11 meta-analyses that found some increased risks reported 16 increased risk estimates, of which 5 pertained to overall cancer and 11 to site-specific cancer. Six of the 16 estimates were derived from randomized trials and 10 from observational data. Estimates of increased risk were strongly inversely correlated with the amount of evidence (number of cancer cases) (Spearman's correlation coefficient = -0.77, P < 0.001). In 4 of the 16 topics, another meta-analysis existed that was larger (n = 2) or included better controlled data (n = 2) and in all 4 cases there was no statistically significantly increased risk of malignancy. No medication or class had substantial and consistent evidence for increased risk of malignancy. However, for most medications we cannot exclude small risks or risks in population subsets. Such risks are unlikely to be possible to document robustly unless very large, collaborative studies with standardized analyses and no selective reporting are carried out.
C1 [Ioannidis, J. P. A.] Stanford Univ, Sch Med, Stanford Prevent Res Ctr, Dept Med, Stanford, CA 94305 USA.
[Ioannidis, J. P. A.] Stanford Univ, Sch Med, Stanford Prevent Res Ctr, Dept Hlth Res & Policy, Stanford, CA 94305 USA.
[Ioannidis, J. P. A.] Stanford Univ, Sch Humanities & Sci, Dept Stat, Stanford, CA 94305 USA.
[Zhou, Y.] Georgetown Univ, Canc Control Program, Lombardi Comprehens Canc Ctr, Washington, DC USA.
[Chang, C. Q.; Schully, S. D.; Khoury, M. J.; Freedman, A. N.] NCI, Div Canc Control & Populat Sci, NIH, Bethesda, MD 20892 USA.
[Khoury, M. J.] Ctr Dis Control & Prevent, Off Publ Hlth Genom, Atlanta, GA USA.
RP Ioannidis, JPA (reprint author), Stanford Univ, Sch Med, Stanford Prevent Res Ctr, 1265 Welch Rd,MSOB X306, Stanford, CA 94305 USA.
EM jioannid@stanford.edu
NR 88
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U1 0
U2 12
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0923-7534
EI 1569-8041
J9 ANN ONCOL
JI Ann. Oncol.
PD JAN
PY 2014
VL 25
IS 1
BP 16
EP 23
DI 10.1093/annonc/mdt372
PG 8
WC Oncology
SC Oncology
GA AA7HR
UT WOS:000331268800004
PM 24310915
ER
PT J
AU Will, JC
Loustalot, F
Hong, YL
AF Will, Julie C.
Loustalot, Fleetwood
Hong, Yuling
TI National Trends in Visits to Physician Offices and Outpatient Clinics
for Angina 1995 to 2010
SO CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES
LA English
DT Article
DE ambulatory care; epidemiology; health services research; office visits
ID UNITED-STATES; CARDIOVASCULAR-DISEASE; CHEST-PAIN; CORONARY; GUIDELINES;
UPDATE; DISPARITIES; PREVENTION; PREVALENCE
AB Background We asked whether visits to physician offices and hospital outpatient clinics for angina have changed over time and whether more frequent use of certain diagnostic techniques or referrals in this setting may account for such changes.
Methods and Results We combined data from the National Ambulatory Medical Care Survey and the National Hospital Ambulatory Medical Care Survey to study visits to physician offices and outpatient departments. We calculated both crude and standardized rates for these visits using a modified version of technical specifications published by the Agency for Healthcare Research and Quality. In 1995 to 1998, there were on average 3.6 million office/clinic visits each year for angina among adults in the United States. By 2007 to 2010, this had declined to 2.3 million visits each year. Angina visit rates per 100 000 declined significantly (P<0.05), with the greatest decline from 1995 through 1998 to 2003 through 2007. Coronary atherosclerotic disease diagnoses also declined after 2002. Both stress testing and referring patients out for care doubled during some study periods.
Conclusions Office and clinic visits for angina have declined over time. This trend parallels findings for both preventable hospitalization and emergency room visits for angina. Previous research's decline in angina hospitalizations is not likely attributable to decreased referrals to hospital and emergency rooms for diagnosis and management. Although changes in International Classification of Diseases, Ninth Revision, Clinical Modification coding guidelines may explain some of the decline in angina and coronary atherosclerotic disease visits, it seems that other factors such as improved treatment or prevention may have played an additional role.
C1 [Will, Julie C.; Loustalot, Fleetwood; Hong, Yuling] Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, Atlanta, GA 30341 USA.
RP Will, JC (reprint author), Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, 4770 Buford Hwy NE,Mailstop F-72, Atlanta, GA 30341 USA.
EM jxw6@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 26
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U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1941-7705
EI 1941-7713
J9 CIRC-CARDIOVASC QUAL
JI Circ.-Cardiovasc. Qual. Outcomes
PD JAN
PY 2014
VL 7
IS 1
BP 110
EP 117
DI 10.1161/CIRCOUTCOMES.113.000450
PG 8
WC Cardiac & Cardiovascular Systems
SC Cardiovascular System & Cardiology
GA AA4MY
UT WOS:000331071200016
PM 24425707
ER
PT J
AU See, I
Shehab, N
Kegler, SR
Laskar, SR
Budnitz, DS
AF See, Isaac
Shehab, Nadine
Kegler, Scott R.
Laskar, S. Raja
Budnitz, Daniel S.
TI Emergency Department Visits and Hospitalizations for Digoxin Toxicity
United States, 2005 to 2010
SO CIRCULATION-HEART FAILURE
LA English
DT Article
DE digoxin; drug-related side effects and adverse reactions; emergency
service; hospital; heart failure; hospitalization
ID INVESTIGATION GROUP TRIAL; HEART-FAILURE; DIG TRIAL; DIGITALIS; DRUG;
MORTALITY; SURVEILLANCE; MORBIDITY; RISK
AB Background Recent data on digoxin prescribing and adverse events are lacking but could help inform the management of digoxin in contemporary heart failure treatment.
Methods and Results We determined nationally representative numbers and rates of emergency department (ED) visits for digoxin toxicity in the United States using 2005 to 2010 reports from the National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance project and the National Ambulatory (and Hospital Ambulatory) Medical Care Surveys. Based on 441 cases, an estimated 5156 (95% confidence interval [CI], 2663-7648) ED visits for digoxin toxicity occurred annually in the United States; more than three fourths (78.8% [95% CI, 73.5%-84.1%]) resulted in hospitalization. Serum digoxin level was 2.0 ng/mL for 95.8% (95% CI, 93.2%-98.4%) of estimated ED visits with levels reported (n=251 cases). The rate of ED visits per 10 000 outpatient prescription visits among patients 85 years was twice that of patients 40 to 84 years (rate ratio, 2.4 [95% CI, 1.2-5.0]); among women, the rate was twice that of men (rate ratio, 2.3 [95% CI, 1.1-4.7]). Digoxin toxicity accounted for an estimated 1.0% (95% CI, 0.6%-1.4%) of ED visits for all adverse drug events among patients 40 years, but an estimated 3.3% (95% CI, 2.3%-4.4%) of ED visits and 5.9% (95% CI, 4.0%-7.9%) of hospitalizations for all adverse drug events among patients 85 years. Estimated annual ED visits and hospitalizations remained relatively constant from 2005 to 2010.
Conclusions Digoxin toxicity is not declining; more careful prescribing to high-risk groups and improved monitoring of serum levels might be needed to reduce morbidity from outpatient digoxin use.
C1 [See, Isaac; Shehab, Nadine; Budnitz, Daniel S.] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA 30333 USA.
[See, Isaac] Ctr Dis Control & Prevent, Epidem Intelligence Serv, Off Sci Educ & Lab Serv, Atlanta, GA 30333 USA.
[Kegler, Scott R.] Ctr Dis Control & Prevent, Div Anal Res & Practice Integrat, Natl Ctr Injury Prevent & Control, Atlanta, GA 30333 USA.
[Laskar, S. Raja] Emory Univ, Sch Med, Div Cardiol, Atlanta, GA 30322 USA.
RP See, I (reprint author), Ctr Dis Control & Prevent, Div Healthcare Qual Promot, 1600 Clifton Rd NE Mailstop A-24, Atlanta, GA 30333 USA.
EM isee@cdc.gov
FU Centers for Disease Control and Prevention
FX This work was funded by the Centers for Disease Control and Prevention.
NR 43
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U1 0
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1941-3289
EI 1941-3297
J9 CIRC-HEART FAIL
JI Circ.-Heart Fail.
PD JAN
PY 2014
VL 7
IS 1
BP 28
EP 34
DI 10.1161/CIRCHEARTFAILURE.113.000784
PG 7
WC Cardiac & Cardiovascular Systems
SC Cardiovascular System & Cardiology
GA AA4ND
UT WOS:000331071800005
PM 24300242
ER
PT J
AU See, I
Shugart, A
Lamb, C
Kallen, AJ
Patel, PR
Sinkowitz-Cochran, RL
AF See, Isaac
Shugart, Alicia
Lamb, Carrie
Kallen, Alexander J.
Patel, Priti R.
Sinkowitz-Cochran, Ronda L.
TI Infection Control and Bloodstream Infection Prevention: The Perspective
Of Patients Receiving Hemodialysis
SO NEPHROLOGY NURSING JOURNAL
LA English
DT Article
DE Bloodstream infections; hemodialysis; infection control; patient
education; patient safety
ID EDUCATION MODEL
AB Patients on hemodialysis, particularly those dialyzed through central lines, are at risk of acquiring bloodstream infections. Strategies to prevent bloodstream infections in patients on dialysis include educating patients about infection prevention, although patients' perspectives on this topic are not known. During focus groups conducted to explore these issues, patients reported that education on infection prevention should begin early in the process of dialysis, and that patients should be actively engaged as partners in infection prevention.
C1 [See, Isaac; Shugart, Alicia; Kallen, Alexander J.; Patel, Priti R.; Sinkowitz-Cochran, Ronda L.] Ctr Dis Control & Prevent CDC, Div Healthcare Qual Promot, Atlanta, GA 30333 USA.
[Lamb, Carrie] Dialysis Patient Citizens, Congress & State Relat, Washington, DC USA.
RP See, I (reprint author), Ctr Dis Control & Prevent CDC, Div Healthcare Qual Promot, Atlanta, GA 30333 USA.
EM isee@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 10
TC 2
Z9 2
U1 0
U2 1
PU JANNETTI PUBLICATIONS, INC
PI PITMAN
PA EAST HOLLY AVENUE, BOX 56, PITMAN, NJ 08071-0056 USA
SN 1526-744X
EI 2163-5390
J9 NEPHROL NURS J
JI Nephrol. Nurs. J.
PD JAN-FEB
PY 2014
VL 41
IS 1
BP 37
EP +
PG 4
WC Nursing; Urology & Nephrology
SC Nursing; Urology & Nephrology
GA AA9PY
UT WOS:000331426600005
PM 24689263
ER
PT J
AU Agwu, AL
Chang, JY
Wiegand, RE
Wheeling, JT
Bohannon, BA
Dominguez, KL
AF Agwu, Allison L.
Chang, Jennifer Y.
Wiegand, Ryan E.
Wheeling, John T.
Bohannon, Beverly A.
Dominguez, Kenneth L.
CA LEGACY Consortium
TI Prevalence and Outcomes of Recycling NNRTIs Despite Documented NNRTI
Resistance in HIV-Infected Children and Youth
SO AIDS PATIENT CARE AND STDS
LA English
DT Article
ID PATIENT-RELATED RISKS; ANTIRETROVIRAL TREATMENT; UNITED-STATES;
NEVIRAPINE EXPOSURE; THERAPY; NONADHERENCE; ADOLESCENTS; ADHERENCE;
MUTATIONS; FAILURE
AB Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are commonly used in pediatric patients; however, rapid development of resistance, due to non-adherence and cross-resistance, results in their discontinuation and limits their recycling. We evaluated the clinical experience of recycling NNRTIs despite documented NNRTI resistance (NNRTI-R), and examined virologic and CD4 cell count outcomes among participants enrolled in Longitudinal Epidemiologic Study to Gain Insight into HIV/AIDS in Children and Youth (LEGACY), a national HIV-infected pediatric cohort. We conducted a retrospective analysis of LEGACY participants with major NNRTI-R. Using chi-square analyses and logistic regression, we examined demographic and clinical factors associated with prescription of NNRTIs despite documented NNRTI-R, and associated changes in plasma HIV RNA viral load and CD4 cell counts. Sixteen of 133 (12%) participants with documented NNRTI-R re-started NNRTIs for a median of 370 days (IQR 105-919) with a median 402 days (IQR 70-841) between documentation of NNRTI-R to NNRTI recycling. Participants recycling NNRTIs were less likely to have documented past non-adherence (40.0% vs. 69.2%; p=0.02). Among twelve patients with virologic data at 24 (+/- 8) weeks; seven (58.3%) experienced virologic suppression while on the recycled NNRTI-based regimens. Of the five who failed to suppress, three with subsequent genotyping developed additional NNRTI-R mutations compromising higher generation NNRTIs. While NNRTI's were recycled in only a small fraction of LEGACY participants harboring NNRTI-R mutations, such recycling increased the risk of inducing further resistance mutations that compromised use of higher generation NNRTIs.
C1 [Agwu, Allison L.] Johns Hopkins Med Inst, Dept Pediat Infect Dis, Baltimore, MD 21287 USA.
[Chang, Jennifer Y.; LEGACY Consortium] Johns Hopkins Med Inst, Dept Pediat, Baltimore, MD 21287 USA.
[Wiegand, Ryan E.; Bohannon, Beverly A.; Dominguez, Kenneth L.] Ctr Dis Control, Div HIV AIDS Prevent, Atlanta, GA 30333 USA.
[Wheeling, John T.] Northrop Grumman Inc, Atlanta, GA USA.
RP Agwu, AL (reprint author), Johns Hopkins Med Inst, Dept Pediat Infect Dis, 200 N Wolfe St,Room 3145, Baltimore, MD 21287 USA.
EM ageorg10@jhmi.edu
FU Centers for Disease Control and Prevention, Atlanta GA [200-2004-09976];
National Institutes of Allergy and Infectious Diseases [1K23 AI084549];
Johns Hopkins Ross Clinician Scientist Award
FX The LEGACY project was funded by the Centers for Disease Control and
Prevention, Atlanta GA, contract number 200-2004-09976.; Dr. Agwu was
supported by the National Institutes of Allergy and Infectious Diseases
(1K23 AI084549) and the Johns Hopkins Ross Clinician Scientist Award.
NR 18
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U1 0
U2 1
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1087-2914
EI 1557-7449
J9 AIDS PATIENT CARE ST
JI Aids Patient Care STDS
PD JAN 1
PY 2014
VL 28
IS 1
BP 10
EP 14
DI 10.1089/apc.2013.0308
PG 5
WC Public, Environmental & Occupational Health; Infectious Diseases
SC Public, Environmental & Occupational Health; Infectious Diseases
GA AA0SX
UT WOS:000330808800003
PM 24428795
ER
PT J
AU Crews, DC
Kuczmarski, MF
Grubbs, V
Hedgeman, E
Shahinian, VB
Evans, MK
Zonderman, AB
Burrows, NR
Williams, DE
Saran, R
Powe, NR
AF Crews, Deidra C.
Kuczmarski, Marie Fanelli
Grubbs, Vanessa
Hedgeman, Elizabeth
Shahinian, Vahakn B.
Evans, Michele K.
Zonderman, Alan B.
Burrows, Nilka Rios
Williams, Desmond E.
Saran, Rajiv
Powe, Neil R.
CA Ctr Disease Control & Preven
TI Effect of Food Insecurity on Chronic Kidney Disease in Lower-Income
Americans
SO AMERICAN JOURNAL OF NEPHROLOGY
LA English
DT Article
DE Socioeconomic status; Disparity; Nutrition
ID GLOMERULAR-FILTRATION-RATE; SOCIOECONOMIC-STATUS; NATIONAL-HEALTH;
RACIAL DISPARITIES; SERUM CREATININE; UNITED-STATES; POVERTY;
PREVALENCE; NUTRITION; ALBUMINURIA
AB Background: The relation of food insecurity (inability to acquire nutritionally adequate and safe foods) and chronic kidney disease (CKD) is unknown. We examined whether food insecurity is associated with prevalent CKD among lower-income individuals in both the general US adult population and an urban population. Methods: We conducted cross-sectional analyses of lower-income participants of the National Health and Nutrition Examination Survey (NHANES) 2003-2008 (n = 9,126) and the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study (n = 1,239). Food insecurity was defined based on questionnaires and CKD was defined by reduced estimated glomerular filtration rate or albuminuria; adjustment was performed with multivariable logistic regression. Results: In NHANES, the age-adjusted prevalence of CKD was 20.3, 17.6, and 15.7% for the high, marginal, and no food insecurity groups, respectively. Analyses adjusting for sociodemographics and smoking status revealed high food insecurity to be associated with greater odds of CKD only among participants with either diabetes (OR = 1.67, 95% CI: 1.14-2.45 comparing high to no food insecurity groups) or hypertension (OR = 1.37, 95% CI: 1.03-1.82). In HANDLS, the age-adjusted CKD prevalence was 5.9 and 4.6% for those with and without food insecurity, respectively (p = 0.33). Food insecurity was associated with a trend towards greater odds of CKD (OR = 1.46, 95% CI: 0.98-2.18) with no evidence of effect modification across diabetes, hypertension, or obesity subgroups. Conclusion: Food insecurity may contribute to disparities in kidney disease, especially among persons with diabetes or hypertension, and is worthy of further study. (C) 2014 S. Karger AG, Basel
C1 [Crews, Deidra C.] Johns Hopkins Med Inst, Dept Med, Div Nephrol, Baltimore, MD 21205 USA.
[Crews, Deidra C.] Johns Hopkins Med Inst, Welch Ctr Prevent Epidemiol & Clin Res, Baltimore, MD 21205 USA.
[Kuczmarski, Marie Fanelli] Univ Delaware, Dept Behav Hlth & Nutr, Newark, DE USA.
[Grubbs, Vanessa] Univ Calif San Francisco, Dept Med, Div Nephrol, San Francisco, CA USA.
[Hedgeman, Elizabeth; Shahinian, Vahakn B.; Saran, Rajiv] Univ Michigan, Dept Med, Div Nephrol, Ann Arbor, MI 48109 USA.
[Evans, Michele K.; Zonderman, Alan B.] NIA, NIH, Baltimore, MD USA.
[Burrows, Nilka Rios; Williams, Desmond E.] Ctr Dis Control & Prevent, Div Diabet Translat, Atlanta, GA USA.
[Powe, Neil R.] Univ Calif San Francisco, San Francisco Gen Hosp, Dept Med, San Francisco, CA USA.
RP Crews, DC (reprint author), Johns Hopkins Univ, Sch Med, Div Nephrol, Johns Hopkins Bayview Med Ctr, 301 Mason F Lord Dr,Suite 2500, Baltimore, MD 21224 USA.
EM dcrews1@jhmi.edu
RI Nguyen, Giang/D-9027-2016
FU CDC [1U58DP003839-01]; Intramural Research Program of the NIA, National
Institutes of Health; Harold Amos Medical Faculty Development Program of
the Robert Wood Johnson Foundation; National Institute of Diabetes and
Digestive and Kidney Diseases (NIDDK) [K23 DK093710]; NIDDK [R01
DK78124]
FX This project was supported under a cooperative agreement from the CDC,
grant 1U58DP003839-01. The findings and conclusions in this report are
those of the authors and do not necessarily represent the official
position of the CDC.; This work was supported by the Intramural Research
Program of the NIA, National Institutes of Health. Dr. Crews and Dr.
Grubbs were supported by the Harold Amos Medical Faculty Development
Program of the Robert Wood Johnson Foundation.; Dr. Grubbs was also
supported by grant K23 DK093710 from the National Institute of Diabetes
and Digestive and Kidney Diseases (NIDDK). Dr. Powe was partially
supported by grant R01 DK78124 from the NIDDK.
NR 52
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U2 10
PU KARGER
PI BASEL
PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND
SN 0250-8095
EI 1421-9670
J9 AM J NEPHROL
JI Am. J. Nephrol.
PY 2014
VL 39
IS 1
BP 27
EP 35
DI 10.1159/000357595
PG 9
WC Urology & Nephrology
SC Urology & Nephrology
GA 302VF
UT WOS:000330632300005
PM 24434743
ER
PT J
AU Baillot, A
Pelletier, C
Dunbar, P
Geiss, L
Johnson, JA
Leiter, LA
Langlois, MF
AF Baillot, Aurelie
Pelletier, Catherine
Dunbar, Peggy
Geiss, Linda
Johnson, Jeffrey A.
Leiter, Lawrence A.
Langlois, Marie-France
TI Profile of adults with type 2 diabetes and uptake of clinical care best
practices: Results from the 2011 Survey on Living with Chronic Diseases
in Canada - Diabetes component
SO DIABETES RESEARCH AND CLINICAL PRACTICE
LA English
DT Article
DE Diabetes; Lifestyle management; Clinical monitoring; Health care
ID CARDIOVASCULAR RISK-FACTORS; LIFE-STYLE INTERVENTION; MULTIFACTORIAL
INTERVENTION; COST-EFFECTIVENESS; MEDICAL INFORMATION; PRACTICE
GUIDELINES; CONTROLLED-TRIAL; GLYCEMIC CONTROL; IMPROVEMENT; PROTECTION
AB Aims: This study aimed to (1) describe the profile of adults with type 2 diabetes (T2D) in Canada and (2) assess the uptake of clinical care best practices, as defined by the Canadian Diabetes Association (CDA) Clinical Practice Guidelines (CPGs).
Methods: We used data from the 2011 Survey on Living with Chronic Diseases in Canada - Diabetes component. Participants were aged 20 years and older, living in the 10 Canadian provinces, with self-reported T2D. Descriptive analyses present the prevalence of complications and comorbidities, as well as the level of clinical monitoring and self-monitoring/ lifestyle management recommendations participants received.
Results: We included 2335 participants with T2D, a mean age of 62.9 years, and high prevalence of complications/comorbidities and prescription medication use. Most participants reported being monitored as recommended for eye disease (73.9%), weight (81.0%), blood pressure (89.0%) and blood cholesterol levels (94.3%), but only 65.5% reported having at least two HbA1c tests during the last year and 46.5% reported an annual foot examination by a health professional. About two-thirds of the participants reported having received recommendations on weight management (59.9%) and physical activity (64.7%) from a health professional in the previous year; only 47.8% of the participants reported having received diet counseling to improve diabetes control.
Conclusion: Although the uptake of CDA CPGs for clinical and self-monitoring was high, with the majority of the participants reporting meeting most indicators, it was lower for HbA1c measurement and foot examination. Uptake of lifestyle management recommendations provided by health professionals was also significantly lower. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
C1 [Baillot, Aurelie; Langlois, Marie-France] Univ Sherbrooke, Div Endocrinol, Dept Med, Etienne LeBel Clin Res Ctr,CHU Sherbrooke, Sherbrooke, PQ J1K 2R1, Canada.
[Pelletier, Catherine] Publ Hlth Agcy Canada, Ottawa, ON, Canada.
[Dunbar, Peggy] Diabet Care Program Nova Scotia, Halifax, NS, Canada.
[Geiss, Linda] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Johnson, Jeffrey A.] Univ Alberta, Sch Publ Hlth, Edmonton, AB, Canada.
[Leiter, Lawrence A.] Univ Toronto, St Michaels Hosp, Li KaShing Knowledge Inst, Div Endocrinol & Metab,Keenan Res Ctr, Toronto, ON, Canada.
RP Langlois, MF (reprint author), Univ Sherbrooke, Ctr Hosp, Div Endocrinol, 3001,12E Ave Nord, Sherbrooke, PQ J1H 5N4, Canada.
EM Marie-France.Langlois@USherbrooke.ca
FU Fonds de la recherche du Quebec Sante (FRQS); FRQS
FX Marie-France Langlois is recipient of a National researcher award from
the Fonds de la recherche du Quebec Sante (FRQS). The Etienne-LeBel
Clinical Research Center is an FRQS funded research center. Jeffrey
Johnson is a Senior Scholar with Alberta Innovates-Health Solutions and
a Centennial Professor at the University of Alberta.
NR 34
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U1 0
U2 5
PU ELSEVIER IRELAND LTD
PI CLARE
PA ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000,
IRELAND
SN 0168-8227
EI 1872-8227
J9 DIABETES RES CLIN PR
JI Diabetes Res. Clin. Pract.
PD JAN
PY 2014
VL 103
IS 1
BP 11
EP 19
DI 10.1016/j.diabres.2013.11.022
PG 9
WC Endocrinology & Metabolism
SC Endocrinology & Metabolism
GA 301ZW
UT WOS:000330572000002
PM 24369983
ER
PT J
AU Pridjian, G
Sirois, P
McRae, R
Hinckley, A
Rasmussen, S
Kissinger, P
Buekens, P
Hayes, E
O'Leary, D
Kuhn, S
Swan, K
Xiong, X
Wesson, D
AF Pridjian, Gabriella
Sirois, Patricia
McRae, Robert
Hinckley, Alison
Rasmussen, Sonja
Kissinger, Patricia
Buekens, Pierre
Hayes, Edward
O'Leary, Dan
Kuhn, Stephanie
Swan, Ken
Xiong, Xu
Wesson, Dawn
TI A prospective study of pregnancy and newborn outcomes in mothers with
West Nile virus (WNV) illness during pregnancy
SO AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
LA English
DT Meeting Abstract
CT 34th Annual Scientific Pregnancy Meeting of the
Society-for-Maternal-Fetal-Medicine
CY FEB 03-08, 2014
CL New Orleans, LA
SP Soc Maternal Fetal Med
C1 [Pridjian, Gabriella; Sirois, Patricia; McRae, Robert; Kissinger, Patricia; Buekens, Pierre; Swan, Ken; Xiong, Xu; Wesson, Dawn] Tulane Univ, New Orleans, LA 70118 USA.
[Hinckley, Alison; Hayes, Edward; O'Leary, Dan; Kuhn, Stephanie] Ctr Dis Control & Prevent, Ft Collins, CO USA.
[Rasmussen, Sonja] Ctr Dis Control & Prevent, Atlanta, GA USA.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0002-9378
EI 1097-6868
J9 AM J OBSTET GYNECOL
JI Am. J. Obstet. Gynecol.
PD JAN
PY 2014
VL 210
IS 1
SU S
BP S197
EP S197
PG 1
WC Obstetrics & Gynecology
SC Obstetrics & Gynecology
GA 298KK
UT WOS:000330322600389
ER
PT J
AU Thompson, J
Kuklina, E
Bateman, B
Callaghan, W
James, A
Grotegut, C
AF Thompson, Jennifer
Kuklina, Elena
Bateman, Brian
Callaghan, William
James, Andra
Grotegut, Chad
TI Medical and pregnancy complications among women with congenital heart
disease at delivery
SO AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
LA English
DT Meeting Abstract
CT 34th Annual Scientific Pregnancy Meeting of the
Society-for-Maternal-Fetal-Medicine
CY FEB 03-08, 2014
CL New Orleans, LA
SP Soc Maternal Fetal Med
C1 [Thompson, Jennifer; Kuklina, Elena; Grotegut, Chad] Duke Univ, Med Ctr, Durham, NC USA.
[Kuklina, Elena; Callaghan, William] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Bateman, Brian] Harvard Univ, Boston, MA 02115 USA.
[James, Andra] Univ Virginia, Charlottesville, VA USA.
NR 0
TC 1
Z9 1
U1 0
U2 1
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0002-9378
EI 1097-6868
J9 AM J OBSTET GYNECOL
JI Am. J. Obstet. Gynecol.
PD JAN
PY 2014
VL 210
IS 1
SU S
BP S28
EP S28
PG 1
WC Obstetrics & Gynecology
SC Obstetrics & Gynecology
GA 298KK
UT WOS:000330322600046
ER
PT J
AU Rybak, ME
Pao, CI
Pfeiffer, CM
AF Rybak, Michael E.
Pao, Ching-I
Pfeiffer, Christine M.
TI Determination of urine caffeine and its metabolites by use of
high-performance liquid chromatography-tandem mass spectrometry:
estimating dietary caffeine exposure and metabolic phenotyping in
population studies
SO ANALYTICAL AND BIOANALYTICAL CHEMISTRY
LA English
DT Article
DE Caffeine; Urine; Biomarkers; Dietary intake; Phenotyping; Mass
spectrometry; NHANES
ID IN-VIVO EVALUATION; XANTHINE-OXIDASE; GENETIC POLYMORPHISMS;
EXTRACTIONLESS METHOD; CYP1A2 ACTIVITY; COFFEE; METAANALYSIS;
CONSUMPTION; PROBE; METHYLXANTHINES
AB We have developed and validated a high-performance liquid chromatography-tandem mass spectrometric (LC-MS/MS) method for determining urine caffeine and 14 caffeine metabolites suitable for estimating caffeine exposure and metabolic phenotyping in population studies. Sample preparation consisted solely of a series of simple reagent treatments at room temperature. Stable isotope-labeled analogs were used as internal standards for all analytes. We developed rapid LC-MS/MS separations for both positive and negative ion mode electrospray ionizations to maximize measurement sensitivity. Limits of detection were 0.05-0.1 mu mol/L depending on the analytes. Method imprecision, based on total coefficients of variation, was generally < 7 % when analyte concentration was > 1 mu mol/L. Analyte recoveries were typically within 10 % of being quantitative (100 %), and good agreement was observed among analytes measured across different MS/MS transitions. We applied this method to the analysis of a convenience set of human urine samples (n = 115) and were able to detect a majority of the analytes in a parts per thousand yen99 % of samples as well as calculate caffeine metabolite phenotyping ratios for cytochrome P450 1A2 and N-acetyltransferase 2. Whereas existing LC-MS/MS methods are limited in number of caffeine metabolites for which they are validated, or are designed for studies in which purposely elevated caffeine levels are expected, our method is the first of its kind designed specifically for the rapid, sensitive, accurate, and precise measurement of urine caffeine and caffeine metabolites at concentrations relevant to population studies.
C1 [Rybak, Michael E.; Pao, Ching-I; Pfeiffer, Christine M.] US Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Atlanta, GA 30341 USA.
RP Rybak, ME (reprint author), US Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, 4770 Buford Highway,MS F-55, Atlanta, GA 30341 USA.
EM MRybak@cdc.gov
OI Rybak, Michael/0000-0003-1650-8581
NR 47
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U1 1
U2 29
PU SPRINGER HEIDELBERG
PI HEIDELBERG
PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
SN 1618-2642
EI 1618-2650
J9 ANAL BIOANAL CHEM
JI Anal. Bioanal. Chem.
PD JAN
PY 2014
VL 406
IS 3
BP 771
EP 784
DI 10.1007/s00216-013-7506-9
PG 14
WC Biochemical Research Methods; Chemistry, Analytical
SC Biochemistry & Molecular Biology; Chemistry
GA 288QD
UT WOS:000329625800012
PM 24306330
ER
PT J
AU Andacht, TM
Pantazides, BG
Crow, BS
Fidder, A
Noort, D
Thomas, JD
Blake, TA
Johnson, RC
AF Andacht, Tracy M.
Pantazides, Brooke G.
Crow, Brian S.
Fidder, Alex
Noort, Daan
Thomas, Jerry D.
Blake, Thomas A.
Johnson, Rudolph C.
TI Enhanced Throughput Method for Quantification of Sulfur Mustard Adducts
to Human Serum Albumin Via Isotope Dilution Tandem Mass Spectrometry
SO JOURNAL OF ANALYTICAL TOXICOLOGY
LA English
DT Article
ID BETA-LYASE METABOLITES; PROTEIN ADDUCTS; BIOLOGICAL FATE; HUMAN URINE;
IMMUNOCHEMICAL DETECTION; SENSITIVE METHOD; IN-VITRO; EXPOSURE;
QUANTITATION; PLASMA
AB Here, we report an enhanced throughput method for the diagnosis of human exposure to sulfur mustard. A hydroxyethylthioethyl (HETE) ester-adducted tripeptide, produced by pronase digestion of human serum albumin, was selected as the quantitative exposure biomarker. Cibacron Blue enrichment was developed from an established cartridge method into a 96-well plate format, increasing throughput and ruggedness. This new method decreased sample volume 2.5-fold. Addition of a precipitation and solid-phase extraction concentration step increased the sensitivity of the method. With the conversion to a 96-well plate and optimization of chromatography, the method resulted in a 3-fold decrease in analysis time. Inclusion of a confirmation ion has increased specificity. The method was found to be linear between 0.050 and 50 mu M sulfur mustard exposure with a precision for both quality control samples of <= 6.5% relative standard deviation and an accuracy of >96%. The limit of detection (3S(o)) was calculated to be similar to 0.0048 mM, an exposure value similar to that of the HETE-albumin adduct method first described by Noort and co-workers (Noort et al., 1999; Noort el al., 2004) which used protein precipitation to isolate albumin. A convenience set of 124 plasma samples from healthy unexposed individuals was analyzed using this method to assess background levels of exposure to sulfur mustard; no positive results were detected.
C1 [Andacht, Tracy M.; Pantazides, Brooke G.; Crow, Brian S.; Thomas, Jerry D.; Blake, Thomas A.; Johnson, Rudolph C.] Ctr Dis Control & Prevent, Emergency Response Branch, Div Sci Lab, Natl Ctr Environm Hlth, Atlanta, GA 30341 USA.
[Fidder, Alex; Noort, Daan] Netherlands Org Appl Sci Res TNO, Rijswijk, Netherlands.
RP Johnson, RC (reprint author), Ctr Dis Control & Prevent, Emergency Response Branch, Div Sci Lab, Natl Ctr Environm Hlth, 4770 Buford Highway NE, Atlanta, GA 30341 USA.
EM rmj6@cdc.gov
FU Centers for Disease Control and Prevention; Defense Threat Reduction
Agency (DTRA)
FX This work was funded by the Centers for Disease Control and Prevention
and the Defense Threat Reduction Agency (DTRA).
NR 50
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U1 0
U2 17
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0146-4760
EI 1945-2403
J9 J ANAL TOXICOL
JI J. Anal. Toxicol.
PD JAN-FEB
PY 2014
VL 38
IS 1
BP 8
EP 15
DI 10.1093/jat/bkt088
PG 8
WC Chemistry, Analytical; Toxicology
SC Chemistry; Toxicology
GA 300EA
UT WOS:000330446000003
PM 24201816
ER
PT J
AU Park, J
Ahmadi, SF
Streja, E
Molnar, MZ
Flegar, KM
Gillen, D
Kovesdy, CP
Kalantar-Zadeh, K
AF Park, Jongha
Ahmadi, Seyed-Foad
Streja, Elani
Molnar, Miklos Z.
Flegar, Katherine M.
Gillen, Daniel
Kovesdy, Csaba P.
Kalantar-Zadeh, Kamyar
TI Obesity Paradox in End-Stage Kidney Disease Patients
SO PROGRESS IN CARDIOVASCULAR DISEASES
LA English
DT Review
DE Obesity paradox; Reverse epidemiology; Dialysis; Visceral fat
ID BODY-MASS INDEX; MAINTENANCE HEMODIALYSIS-PATIENTS; INFLAMMATION COMPLEX
SYNDROME; CARDIOVASCULAR RISK-FACTORS; CHRONIC HEART-FAILURE;
TUMOR-NECROSIS-FACTOR; PERITONEAL-DIALYSIS; REVERSE EPIDEMIOLOGY;
RENAL-DISEASE; UNITED-STATES
AB In the general population, obesity is associated with increased cardiovascular risk and decreased survival. In patients with end-stage renal disease (ESRD), however, an "obesity paradox" or "reverse epidemiology" (to include lipid and hypertension paradoxes) has been consistently reported, i.e. a higher body mass index (BMI) is paradoxically associated with better survival. This survival advantage of large body size is relatively consistent for hemodialysis patients across racial and regional differences, although published results are mixed for peritoneal dialysis patients. Recent data indicate that both higher skeletal muscle mass and increased total body fat are protective, although there are mixed data on visceral (intra-abdominal) fat. The obesity paradox in ESRD is unlikely to be due to residual confounding alone and has biologic plausibility. Possible causes of the obesity paradox include protein-energy wasting and inflammation, time discrepancy among competitive risk factors (undemutrition versus overnutrition), hemodynamic stability, alteration of circulatory cytokines, sequestration of uremic toxin in adipose tissue, and endotoxin-lipoprotein interaction. The obesity paradox may have significant clinical implications in the management of ESRD patients especially if obese dialysis patients are forced to lose weight upon transplant wait-listing. Well-designed studies exploring the causes and consequences of the reverse epidemiology of cardiovascular risk factors, including the obesity paradox, among ESRD patients could provide more information on mechanisms. These could include controlled trials of nutritional and pharmacologic interventions to examine whether gain in lean body mass or even body fat can improve survival and quality of life in these patients. (C) 2014 Elsevier Inc. All rights reserved.
C1 [Park, Jongha; Ahmadi, Seyed-Foad; Streja, Elani; Molnar, Miklos Z.; Gillen, Daniel; Kalantar-Zadeh, Kamyar] Univ Calif Irvine, Sch Med, Harold Simmons Ctr Kidney Dis Res & Epidemiol, Orange, CA 92868 USA.
[Park, Jongha] Univ Ulsan, Coll Med, Ulsan Univ Hosp, Div Nephrol, Ulsan 680749, South Korea.
[Flegar, Katherine M.] Ctr Dis Control & Prevent CDC, Hyattsville, MD USA.
[Gillen, Daniel] Univ Calif Irvine, Dept Stat, Irvine, CA USA.
[Kovesdy, Csaba P.] Memphis Vet Affairs Med Ctr, Div Nephrol, Memphis, TN USA.
[Kovesdy, Csaba P.] Univ Tennessee, Ctr Hlth Sci, Div Nephrol, Memphis, TN 38163 USA.
[Kalantar-Zadeh, Kamyar] UCLA Fielding Sch Publ Hlth, Dept Epidemiol, Los Angeles, CA USA.
RP Park, J (reprint author), Ulsan Univ Hosp, 290-3 Jeonha Dong, Ulsan 682714, South Korea.
EM jonghaparkmd@gmail.com; kamkal@ucla.edu
OI Flegal, Katherine/0000-0002-0838-469X; Molnar, Miklos
Z/0000-0002-9665-330X; Kalantar-Zadeh, Kamyar/0000-0002-8666-0725
FU National Institute of Diabetes, Digestive and Kidney Disease
[R01-DK078106, R01-DK096920, K24-DK091419]; National Institute on Aging
of the National Institutes of Health [R21-AG047036]; Centers for Disease
Control and Prevention
FX KKZ and CPK are supported by the National Institute of Diabetes,
Digestive and Kidney Disease grants R01-DK078106 and R01-DK096920, and
KKZ is supported additionally by grant K24-DK091419 and a philanthropist
grant from Mr. Harold Simmons. MZM and KKZ are supported by the National
Institute on Aging of the National Institutes of Health grant
R21-AG047036. Disclaimer: The findings and conclusions in this report
are those of the authors and not necessarily of the Centers for Disease
Control and Prevention.
NR 90
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U2 13
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0033-0620
EI 1873-1740
J9 PROG CARDIOVASC DIS
JI Prog. Cardiovasc. Dis.
PD JAN-FEB
PY 2014
VL 56
IS 4
BP 415
EP 425
DI 10.1016/j.pcad.2013.10.005
PG 11
WC Cardiac & Cardiovascular Systems
SC Cardiovascular System & Cardiology
GA 297LC
UT WOS:000330255900007
PM 24438733
ER
PT J
AU Flak, AL
Su, S
Bertrand, J
Denny, CH
Kesmodel, US
Cogswell, ME
AF Flak, Audrey L.
Su, Su
Bertrand, Jacquelyn
Denny, Clark H.
Kesmodel, Ulrik S.
Cogswell, Mary E.
TI The Association of Mild, Moderate, and Binge Prenatal Alcohol Exposure
and Child Neuropsychological Outcomes: A Meta-Analysis
SO ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
LA English
DT Article
DE Prenatal Alcohol Exposure; Child Neurodevelopment; Systematic Review;
Meta-Analysis
ID ACADEMIC-ACHIEVEMENT; COGNITIVE DEFICITS; MOTOR DEVELOPMENT; LIGHT
DRINKING; TOBACCO USE; AGE 6; PREGNANCY; INFANT; RISK; CONSUMPTION
AB BackgroundThe objective of this review is to evaluate the literature on the association between mild, moderate, and binge prenatal alcohol exposure and child neurodevelopment.
MethodsMeta-analysis with systematic searches of MEDLINE (1970 through August 2012), EMBASE (1988 through August 2012), and PsycINFO((R)) (1970 through August 2012) and examination of selected references.
ResultsFrom 1,593 articles, we identified 34 presenting data from cohort studies that met our inclusion criteria. Information on study population, outcomes, measurement instruments, timing and quantification of alcohol exposure, covariates, and results was abstracted. Outcomes included academic performance, attention, behavior, cognition, language skills, memory, and visual and motor development. The quality of each article was assessed by 2 researchers using the Newcastle-Ottawa Scale. Based on 8 studies of 10,000 children aged 6months through 14years, we observed a significant detrimental association between any binge prenatal alcohol exposure and child cognition (Cohen's d [a standardized mean difference score] -0.13; 95% confidence interval [CI], -0.21, -0.05). Based on 3 high-quality studies of 11,900 children aged 9months to 5years, we observed a statistically significant detrimental association between moderate prenatal alcohol exposure and child behavior (Cohen's d -0.15; 95% CI, -0.28, -0.03). We observed a significant, albeit small, positive association between mild-to-moderate prenatal alcohol exposure and child cognition (Cohen's d 0.04; 95% CI, 0.00, 0.08), but the association was not significant after post hoc exclusion of 1 large study that assessed mild consumption nor was it significant when including only studies that assessed moderate alcohol consumption. None of the other completed meta-analyses resulted in statistically significant associations between mild, moderate, or binge prenatal alcohol exposure and child neuropsychological outcomes.
ConclusionsOur findings support previous findings suggesting the detrimental effects of prenatal binge drinking on child cognition. Prenatal alcohol exposure at levels less than daily drinking might be detrimentally associated with child behavior. The results of this review highlight the importance of abstaining from binge drinking during pregnancy and provide evidence that there is no known safe amount of alcohol to consume while pregnant.
C1 [Flak, Audrey L.] Emory Univ, Dept Epidemiol, Rollins Sch Publ Hlth, Atlanta, GA 30332 USA.
[Flak, Audrey L.; Su, Su] Oak Ridge Inst Sci & Educ, Oak Ridge, TN USA.
[Flak, Audrey L.; Bertrand, Jacquelyn; Denny, Clark H.] Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA USA.
[Su, Su] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Atlanta, GA USA.
[Kesmodel, Ulrik S.] Aarhus Univ, Sch Publ Hlth, Dept Epidemiol, Aarhus, Denmark.
[Kesmodel, Ulrik S.] Aarhus Univ Hosp, Dept Obstet & Gynecol, DK-8000 Aarhus, Denmark.
[Cogswell, Mary E.] Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA.
RP Flak, AL (reprint author), Emory Univ, Dept Epidemiol, CNR 3rd Floor,1518 Clifton Rd,Mailstop 1518-002-3, Atlanta, GA 30332 USA.
EM aflak@emory.edu
FU Centers for Disease Control and Prevention (CDC); Oak Ridge Institute
for Science and Education through an interagency agreement between the
U.S. Department of Energy; CDC
FX The authors thank Camille Smith, MS, EdS for her work on outcome
classifications for this study and Gail Bang, MLIS for her development
and completion of the systematic searches. This research was supported
in part by an appointment to the Research Participation Program at the
Centers for Disease Control and Prevention (CDC) administered by the Oak
Ridge Institute for Science and Education through an interagency
agreement between the U.S. Department of Energy and CDC.
NR 60
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U2 39
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0145-6008
EI 1530-0277
J9 ALCOHOL CLIN EXP RES
JI Alcoholism (NY)
PD JAN
PY 2014
VL 38
IS 1
BP 214
EP 226
DI 10.1111/acer.12214
PG 13
WC Substance Abuse
SC Substance Abuse
GA 292EV
UT WOS:000329885900026
PM 23905882
ER
PT J
AU Dorman, SE
Belknap, R
Graviss, EA
Reves, R
Schluger, N
Weinfurter, P
Wang, YP
Cronin, W
Hirsch-Moverman, Y
Teeter, LD
Parker, M
Garrett, DO
Daley, CL
AF Dorman, Susan E.
Belknap, Robert
Graviss, Edward A.
Reves, Randall
Schluger, Neil
Weinfurter, Paul
Wang, Yaping
Cronin, Wendy
Hirsch-Moverman, Yael
Teeter, Larry D.
Parker, Matthew
Garrett, Denise O.
Daley, Charles L.
CA TB Epidemiologic Studies
TI Interferon-gamma Release Assays and Tuberculin Skin Testing for
Diagnosis of Latent Tuberculosis Infection in Healthcare Workers in the
United States
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Article
DE screening; QuantiFERON; T-SPOT.TB; false positive
ID QUANTIFERON-TB-GOLD; WITHIN-SUBJECT VARIABILITY; IN-TUBE ASSAY;
RESPONSES; CONVERSION
AB Rationale: IFN-gamma release assays (IGRAs) are alternatives to tuberculin skin testing (TST) for diagnosis of latent tuberculosis infection. Limited data suggest IGRAs may not perform well for serial testing of healthcare workers (HCWs).
Objectives: Determine the performance characteristics of IGRAs versus TST for serial testing of HCWs.
Methods: A longitudinal study involving 2,563 HCWs undergoing occupational tuberculosis screening at four healthcare institutions in the United States, where the average tuberculosis case rate ranged from 4 to 9 per 100,000 persons. QuantiFERON-TB Gold In-Tube (QFT-GIT), T-SPOT. TB (T-SPOT), and TST were performed at baseline and every 6 months for 18 months between February 2008 and March 2011.
Measurements and Main Results: A total of 2,418 HCWs completed baseline testing, which was positive for 125 (5.2%) by TST, 118 (4.9%) by QFT-GIT, and 144 (6.0%) by T-SPOT. A baseline positive TST with negative IGRAs was associated with bacillus Calmette-Guerin (BCG) vaccination (odds ratio: 25.1 [95% confidence interval: 15.5, 40.5] vs. no BCG). Proportions of participants with test conversion during the study period were 138 of 2,263 (6.1%) for QFT-GIT, 177 of 2,137 (8.3%) for T-SPOT, and 21 of 2,293 (0.9%) for TST (P < 0.001 for QFT-GIT vs. TST and for T-SPOT vs. TST; P = 0.005 for QFT-GIT vs. T-SPOT). Of the QFT-GIT and T-SPOT converters, 81 of 106 (76.4%) and 91 of 118 (77.1%), respectively, were negative when retested 6 months later. There was negative/positive discordance for 15 of 170 (8.8%) participants by QFT-GIT and for 19 of 151 (12.6%) by T-SPOT when blood was drawn 2 weeks later.
Conclusions: Most conversions among HCWs in low TB incidence settings appear to be false positives, and these occurred six to nine times more frequently with IGRAs than TST; repeat testing of apparent converters is warranted.
C1 [Dorman, Susan E.; Wang, Yaping] Johns Hopkins Univ, Sch Med, Baltimore, MD USA.
[Belknap, Robert; Reves, Randall; Parker, Matthew; Daley, Charles L.] Univ Colorado, Sch Med, Denver, CO USA.
[Belknap, Robert; Reves, Randall; Parker, Matthew] Denver Publ Hlth Dept, Denver, CO USA.
[Graviss, Edward A.; Teeter, Larry D.] Methodist Hosp Res Inst, Houston, TX USA.
[Schluger, Neil; Hirsch-Moverman, Yael] Columbia Univ, CP Felton Natl TB Ctr, Int Ctr AIDS Care & Treatment Programs, Mailman Sch Publ Hlth, New York, NY USA.
[Weinfurter, Paul] Westat Corp, Rockville, MD USA.
[Cronin, Wendy] Maryland Dept Hlth & Mental Hyg, Baltimore, MD USA.
[Garrett, Denise O.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Daley, Charles L.] Natl Jewish Hlth, Div Mycobacterial & Resp Infect, Denver, CO 80206 USA.
RP Daley, CL (reprint author), Natl Jewish Hlth, 1400 Jackson St, Denver, CO 80206 USA.
EM daleyc@njhealth.org
FU CDC Tuberculosis Epidemiologic Studies Consortium
FX Supported by contracts from the CDC Tuberculosis Epidemiologic Studies
Consortium to the study sites. Kits and tubes for QuantiFERON-TB Gold
In-Tube testing were purchased from Cellestis, Inc, and kits and tubes
for T-SPOT. TB testing were purchased from Oxford Immunotec. Technical
representatives from Cellestis and Oxford Immunotec provided laboratory
training for QuantiFERON-TB Gold and T-SPOT. TB testing, respectively.
Neither Cellestis nor Oxford Immunotec had any additional role in design
or conduct of the study; collection, management, analysis, or
interpretation of the data; or preparation, review, or approval of the
manuscript.
NR 43
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U1 0
U2 5
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PD JAN 1
PY 2014
VL 189
IS 1
BP 77
EP 87
DI 10.1164/rccm.201302-0365OC
PG 11
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA 290UW
UT WOS:000329784800016
PM 24299555
ER
PT J
AU Walter, ND
Painter, J
Parker, M
Lowenthal, P
Flood, J
Fu, YX
Asis, R
Reves, R
AF Walter, Nicholas D.
Painter, John
Parker, Matthew
Lowenthal, Phillip
Flood, Jennifer
Fu, Yunxin
Asis, Redentor
Reves, Randall
CA TB Epidemiologic Studies
TI Persistent Latent Tuberculosis Reactivation Risk in United States
Immigrants
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Article
DE United States; epidemiology; emigrants and immigrants; guideline; public
health
ID FOREIGN-BORN PERSONS; LOW-INCIDENCE COUNTRY; US-BOUND IMMIGRANTS;
COST-EFFECTIVENESS; INFECTION; REFUGEES; COHORT; PREVALENCE; CANADA;
IMPACT
AB Rationale: Current guidelines limit latent tuberculosis infection (LTBI) evaluation to persons in the United States less than or equal to 5 years based on the assumption that high TB rates among recent entrants are attributable to high LTBI reactivation risk, which declines over time. We hypothesized that high postarrival TB rates may instead be caused by imported active TB.
Objectives: Estimate reactivation and imported TB in an immigrant cohort.
Methods: We linked preimmigration records from a cohort of California-bound Filipino immigrants during 2001-2010 with subsequent TB reports. TB was likely LTBI reactivation if the immigrant had no evidence of active TB at preimmigration examination, likely imported if preimmigration radiograph was abnormal and TB was reported less than or equal to 6 months after arrival, and likely reactivation of inactive TB if radiograph was abnormal but TB was reported more than 6 months after arrival.
Measurements and Main Results: Among 123,114 immigrants, 793 TB cases were reported. Within 1 year of preimmigration examination, 85% of TB was imported; 6 and 9% were reactivation of LTBI and inactive TB, respectively. Conversely, during Years 2-9 after U.S. entry, 76 and 24% were reactivation of LTBI and inactive TB, respectively. The rate of LTBI reactivation (32 per 100,000) did not decline during Years 1-9.
Conclusions: High postarrival TB rates were caused by detection of imported TB through active postarrival surveillance. Among immigrants without active TB at baseline, reported TB did not decline over 9 years, indicating sustained high risk of LTBI reactivation. Revised guidelines should support LTBI screening and treatment more than 5 years after U.S. arrival.
C1 [Walter, Nicholas D.] Univ Colorado Denver, Div Pulm Sci & Crit Care Med, Aurora, CO 80045 USA.
[Walter, Nicholas D.; Parker, Matthew; Reves, Randall] Denver Publ Hlth Dept, Denver Metro TB Control Program, Denver, CO USA.
[Painter, John] Ctr Dis Control & Prevent, Immigrant Refugee & Migrant Hlth Branch, Div Global Migrat & Quarantine, Atlanta, GA USA.
[Lowenthal, Phillip; Flood, Jennifer] Calif Dept Publ Hlth, TB Control Branch, Div Communicable Dis Control, Ctr Infect Dis, Richmond, CA USA.
[Fu, Yunxin] Univ Texas Hlth Sci Ctr Houston, Ctr Human Genet, Houston, TX 77030 USA.
[Fu, Yunxin] Univ Texas Hlth Sci Ctr Houston, Div Biostat, Sch Publ Hlth, Houston, TX 77030 USA.
[Asis, Redentor] St Lukes Med Ctr Extens Clin, Manila, Philippines.
RP Walter, ND (reprint author), Univ Colorado Denver, Div Pulm Sci & Crit Care Med, Anschutz Med Campus,Box C272,9th Floor, Aurora, CO 80045 USA.
EM nicholas.walter@ucdenver.edu
FU TB Epidemiologic Studies Consortium, U.S. Centers for Disease Control
and Prevention; National Institutes of Health [K-12 5K12HL090147-04]
FX Supported by TB Epidemiologic Studies Consortium, U.S. Centers for
Disease Control and Prevention (M.P., Y.F., and R.R.), and National
Institutes of Health grant K-12 5K12HL090147-04 (N.D.W.).
NR 43
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U1 3
U2 7
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PD JAN 1
PY 2014
VL 189
IS 1
BP 88
EP 95
DI 10.1164/rccm.201308-1480OC
PG 8
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA 290UW
UT WOS:000329784800017
PM 24308495
ER
PT J
AU Piesman, J
Hojgaard, A
Ullmann, AJ
Dolan, MC
AF Piesman, Joseph
Hojgaard, Andrias
Ullmann, Amy J.
Dolan, Marc C.
TI Efficacy of an Experimental Azithromycin Cream for Prophylaxis of
Tick-Transmitted Lyme Disease Spirochete Infection in a Murine Model
SO ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
LA English
DT Article
ID BORRELIA-BURGDORFERI INFECTION; SUSTAINED-RELEASE FORMULATION;
IXODES-SCAPULARIS ACARI; DOXYCYCLINE HYCLATE; ANAPLASMA-PHAGOCYTOPHILUM;
UNITED-STATES; PREVENTION; BITE; IXODIDAE; MICE
AB As an alternative to oral prophylaxis for the prevention of tick transmission of Borrelia burgdorferi, we tested antibiotic cream prophylactic formulations in a murine model of spirochete infection. A 4% preparation of doxycycline cream afforded no protection, but a single application of 4% azithromycin cream was 100% protective when applied directly to the tick bite site at the time of tick removal. Indeed, the azithromycin cream was 100% effective when applied at up to 3 days after tick removal and protected 74% of mice exposed to tick bite when applied at up to 2 weeks after tick removal. Azithromycin cream was also protective when applied at a site distal to the tick bite site, suggesting that it was having a systemic effect in addition to a local transdermal effect. Mice that were protected from tick-transmitted infection did not seroconvert and did not infect larval ticks on xenodiagnosis. Azithromycin cream formulations appear to hold promise for Lyme disease prophylaxis.
C1 [Piesman, Joseph; Hojgaard, Andrias; Ullmann, Amy J.; Dolan, Marc C.] Ctr Dis Control & Prevent, Div Vector Borne Dis, Ft Collins, CO USA.
RP Hojgaard, A (reprint author), Ctr Dis Control & Prevent, Div Vector Borne Dis, Ft Collins, CO USA.
EM fth3@cdc.gov
NR 30
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Z9 3
U1 0
U2 5
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0066-4804
EI 1098-6596
J9 ANTIMICROB AGENTS CH
JI Antimicrob. Agents Chemother.
PD JAN
PY 2014
VL 58
IS 1
BP 348
EP 351
DI 10.1128/AAC.01932-13
PG 4
WC Microbiology; Pharmacology & Pharmacy
SC Microbiology; Pharmacology & Pharmacy
GA 287ZL
UT WOS:000329581100044
PM 24165183
ER
PT J
AU Lo, MK
Bird, BH
Chattopadhyay, A
Drew, CP
Martin, BE
Coleman, JD
Rose, JK
Nichol, ST
Spiropoulou, CF
AF Lo, Michael K.
Bird, Brian H.
Chattopadhyay, Anasuya
Drew, Clifton P.
Martin, Brock E.
Coleman, Joann D.
Rose, John K.
Nichol, Stuart T.
Spiropoulou, Christina F.
TI Single-dose replication-defective VSV-based Nipah virus vaccines provide
protection from lethal challenge in Syrian hamsters
SO ANTIVIRAL RESEARCH
LA English
DT Article
DE Henipavirus; Nipah; Vaccine; VSV; Single-dose; Hamster
ID VESICULAR STOMATITIS-VIRUS; LONG-TERM PROTECTION; SUBUNIT VACCINE;
HENIPAVIRUS INFECTION; IMMUNE-RESPONSES; COMPETENT VECTOR;
PARAMYXOVIRUS; PROTEIN; MODEL; MICE
AB Nipah virus (NiV) continues to cause outbreaks of fatal human encephalitis due to spillover from its bat reservoir. We determined that a single dose of replication-defective vesicular stomatitis virus (VSV)-based vaccine vectors expressing either the NiV fusion (F) or attachment (G) glycoproteins protected hamsters from over 1000 times LD50 NiV challenge. This highly effective single-dose protection coupled with an enhanced safety profile makes these candidates ideal for potential use in livestock and humans. Published by Elsevier B.V.
C1 [Lo, Michael K.; Bird, Brian H.; Martin, Brock E.; Coleman, Joann D.; Nichol, Stuart T.; Spiropoulou, Christina F.] Ctr Dis Control & Prevent, Viral Special Pathogens Branch, Atlanta, GA 30333 USA.
[Drew, Clifton P.] Ctr Dis Control & Prevent, Infect Dis Pathol Branch, Atlanta, GA 30333 USA.
[Chattopadhyay, Anasuya; Rose, John K.] Yale Univ, Sch Med, Dept Pathol, New Haven, CT 06510 USA.
RP Lo, MK (reprint author), Ctr Dis Control & Prevent, Viral Special Pathogens Branch, 1600 Clifton Rd,Mailstop G-14, Atlanta, GA 30333 USA.
EM mko2@cdc.gov; ccs8@cdc.gov
OI Lo, Michael/0000-0002-0409-7896
FU NIH Northeast Biodefense Center Grant [U54-AI057158]
FX We thank Mr. Eddie Jackson for assistance with implanting
temperature/identification transponders in the hamsters, and Peter J.
Eworonsky, Abiola Aminu, and Lester E. Slough for assistance in animal
care and husbandry. The findings and conclusions in this report are
those of the authors and do not necessarily represent those of the
Centers for Disease Control and Prevention. This work was supported in
part by NIH Northeast Biodefense Center Grant U54-AI057158.
NR 34
TC 9
Z9 10
U1 0
U2 4
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0166-3542
EI 1872-9096
J9 ANTIVIR RES
JI Antiviral Res.
PD JAN
PY 2014
VL 101
BP 26
EP 29
DI 10.1016/j.antiviral.2013.10.012
PG 4
WC Pharmacology & Pharmacy; Virology
SC Pharmacology & Pharmacy; Virology
GA 290QF
UT WOS:000329772700003
PM 24184127
ER
PT J
AU Mishin, VP
Sleeman, K
Levine, M
Carney, PJ
Stevens, J
Gubareva, LV
AF Mishin, Vasiliy P.
Sleeman, Katrina
Levine, Marnie
Carney, Paul J.
Stevens, James
Gubareva, Larisa V.
TI The effect of the MDCK cell selected neuraminidase D151G mutation on the
drug susceptibility assessment of influenza A(H3N2) viruses
SO ANTIVIRAL RESEARCH
LA English
DT Article
DE Neuraminidase inhibition assay; Pyrosequencing; Recombinant protein;
NA-Star (R) kit; NA-Fluor (TM) kit
ID INHIBITOR RESISTANCE; SURVEILLANCE; SITE
AB Propagation of influenza A(H3N2) viruses in MDCK cells has been associated with the emergence of neuraminidase (NA) variants carrying a change at residue 151. In this study, the pyrosequencing assay revealed that similar to 90% of A(H3N2) virus isolates analyzed (n = 150) contained more than one amino acid variant (D/G/N) at position 151. Susceptibilities of the virus isolates to zanamivir and oseltamivir were assessed using the chemiluminescent and fluorescent NA inhibition (NI) assays. In the chemiluminescent assay, which utilizes NA-Star (R) substrate, up to 13-fold increase in zanamivir-IC50 was detected for isolates containing a high proportion (>50%) of the G151 NA variant. However, an increase in zanamivir-IC(50)s was not seen in the fluorescent assay, which uses MUNANA as substrate. To investigate this discrepancy, recombinant NAs (rNAs) were prepared and tested in both NI assays. Regardless of the assay used, the zanamivir-IC50 for the rNA G151 was much greater (>1500-fold) than that for rNA D151 wildtype. However, zanamivir resistance conferred by the G151 substitution was masked in preparations containing the D151 NA which had much greater activity, especially against MUNANA. In conclusion, the presence of NA D151G variants in cell culture-grown viruses interferes with drug susceptibility assessment and therefore measures need to be implemented to prevent their emergence. Published by Elsevier B.V.
C1 [Mishin, Vasiliy P.; Sleeman, Katrina; Levine, Marnie; Carney, Paul J.; Stevens, James; Gubareva, Larisa V.] Ctr Dis Control & Prevent, Virus Surveillance & Diag Branch, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
[Levine, Marnie] Battelle Mem Inst, Atlanta, GA 30333 USA.
RP Gubareva, LV (reprint author), Mail Stop G-16,1600 Clifton Rd, Atlanta, GA 30333 USA.
EM LGubareva@cdc.gov
NR 13
TC 12
Z9 12
U1 1
U2 7
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0166-3542
EI 1872-9096
J9 ANTIVIR RES
JI Antiviral Res.
PD JAN
PY 2014
VL 101
BP 93
EP 96
DI 10.1016/j.antiviral.2013.11.001
PG 4
WC Pharmacology & Pharmacy; Virology
SC Pharmacology & Pharmacy; Virology
GA 290QF
UT WOS:000329772700012
PM 24239666
ER
PT J
AU Jaacks, LM
Bell, RA
Dabelea, D
D'Agostino, RB
Dolan, LM
Imperatore, G
Klingensmith, G
Lawrence, JM
Saydah, S
Yi-Frazier, J
Mayer-Davis, EJ
AF Jaacks, Lindsay M.
Bell, Ronny A.
Dabelea, Dana
D'Agostino, Ralph B., Jr.
Dolan, Lawrence M.
Imperatore, Giuseppina
Klingensmith, Georgeanna
Lawrence, Jean M.
Saydah, Sharon
Yi-Frazier, Joyce
Mayer-Davis, Elizabeth J.
CA SEARCH Diabet Youth Study Grp
TI Diabetes Self-Management Education Patterns in a US Population-Based
Cohort of Youth With Type 1 Diabetes
SO DIABETES EDUCATOR
LA English
DT Editorial Material
ID YOUNG-PEOPLE; ADOLESCENTS; PREVALENCE; MELLITUS; CHILDREN; SEARCH;
ASSOCIATION; KNOWLEDGE; OUTCOMES; SUPPORT
AB Purpose The purpose of this study is to describe (1) the receipt of diabetes self-management education (DSME) in a large, diverse cohort of US youth with type 1 diabetes (T1DM), (2) the segregation of self-reported DSME variables into domains, and (3) the demographic and clinical characteristics of youth who receive DSME.
Methods Data are from the US population-based cohort SEARCH for Diabetes in Youth. A cross-sectional analysis was employed using data from 1273 youth <20 years of age at the time of diagnosis of T1DM. Clusters of 19 self-reported DSME variables were derived using factor analysis, and their associations with demographic and clinical characteristics were evaluated using polytomous logistic regression.
Results Nearly all participants reported receiving DSME content consistent with survival skills (eg, target blood glucose and what to do for low or high blood glucose), yet gaps in continuing education were identified (eg, fewer than half of the participants reported receiving specific medical nutrition therapy recommendations). Five DSME clusters were explored: receipt of specific MNT recommendations, receipt of diabetes information resources, receipt of clinic visit information, receipt of specific diabetes information, and met with educator or nutritionist. Factor scores were significantly associated with demographic and clinical characteristics, including race/ethnicity, socioeconomic status, and diabetes self-management practices.
Conclusions Health care providers should work together to address reported gaps in DSME to improve patient care.
C1 [Jaacks, Lindsay M.; Mayer-Davis, Elizabeth J.] Univ N Carolina, Dept Nutr, Chapel Hill, NC 27599 USA.
[Bell, Ronny A.] Wake Forest Sch Med, Dept Epidemiol & Prevent, Winston Salem, NC USA.
[Dabelea, Dana; Klingensmith, Georgeanna] Univ Colorado, Dept Pediat, Denver, CO 80202 USA.
[Dabelea, Dana; Klingensmith, Georgeanna] Univ Colorado, Barbara Davis Ctr, Denver, CO 80202 USA.
[D'Agostino, Ralph B., Jr.] Wake Forest Sch Med, Dept Biostat, Winston Salem, NC USA.
[Dolan, Lawrence M.] Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH 45229 USA.
[Imperatore, Giuseppina; Saydah, Sharon] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Lawrence, Jean M.] Kaiser Permanente So Calif, Dept Res & Evaluat, Pasadena, CA 91101 USA.
[Yi-Frazier, Joyce] Seattle Childrens Hosp, Seattle, WA USA.
[Mayer-Davis, Elizabeth J.] Univ N Carolina, Dept Med, Chapel Hill, NC 27599 USA.
RP Mayer-Davis, EJ (reprint author), Univ N Carolina, 2211 McGavran Greenberg Hall,135 Dauer Dr, Chapel Hill, NC 27599 USA.
EM mayerdav@email.unc.edu
RI Dagostino Jr, Ralph/C-4060-2017
OI Dagostino Jr, Ralph/0000-0002-3550-8395
FU HSRD VA [HIR 10-001]; NCATS NIH HHS [UL1 TR001082]; NCCDPHP CDC HHS
[DP-05-069, 1U18DP002709, DP-10-001, U01 DP000244, U01 DP000246, U01
DP000247, U01 DP000248, U01 DP000250, U01 DP000254, U18 DP002708, U18
DP002709, U18 DP002710, U18 DP002714, U18DP000247-06A1, U18DP002708-01,
U18DP002710-01, U18DP002714]; NCRR NIH HHS [M01 RR000037, M01 RR000069,
M01RR00037, M01RR00069, UL1 RR025014, UL1 RR026314, UL1 RR029882,
UL1RR026314-01, UL1RR029882]; NIDDK NIH HHS [K23 DK089017, P30 DK057516,
P30DK57516]; PHS HHS [00097, 200-2010-35171, U48/CCU419249,
U48/CCU519239, U48/CCU819241-3, U48/CCU919219, U58/CCU019235-4]
NR 31
TC 1
Z9 1
U1 0
U2 15
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 0145-7217
EI 1554-6063
J9 DIABETES EDUCATOR
JI Diabetes Educ.
PD JAN
PY 2014
VL 40
IS 1
BP 29
EP 39
DI 10.1177/0145721713512156
PG 11
WC Endocrinology & Metabolism; Public, Environmental & Occupational Health
SC Endocrinology & Metabolism; Public, Environmental & Occupational Health
GA 291YU
UT WOS:000329869600001
PM 24248833
ER
PT J
AU Quarles, CD
Jones, DR
Jarrett, JM
Shakirova, G
Pan, Y
Caldwell, KL
Jones, RL
AF Quarles, C. Derrick, Jr.
Jones, Deanna R.
Jarrett, Jeffery M.
Shakirova, Gulchekhra
Pan, Yi
Caldwell, Kathleen L.
Jones, Robert L.
TI Analytical method for total chromium and nickel in urine using an
inductively coupled plasma-universal cell technology-mass spectrometer
(ICP-UCT-MS) in kinetic energy discrimination (KED) mode
SO JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
LA English
DT Article
ID TRACE-ELEMENTS; WHOLE-BLOOD; METAL; HIP; INTERFERENCES; COLLISION; GAS
AB Biomonitoring and emergency response measurements are an important aspect of the Division of Laboratory Sciences of the National Center for Environmental Health, Centers for Disease Control and Prevention (CDC). The continuing advancement in instrumentation allows for enhancements to existing analytical methods. Prior to this work, chromium and nickel were analyzed on a sector field inductively coupled plasma-mass spectrometer (SF-ICP-MS). This type of instrumentation provides the necessary sensitivity, selectivity, accuracy, and precision but due to the higher complexity of instrumentation and operation, it is not preferred for routine high throughput biomonitoring needs. Instead a quadrupole based method has been developed on a PerkinElmer NexION (TM) 300D ICP-MS. The instrument is operated using 6.0 mL min(-1) helium as the collision cell gas and in kinetic energy discrimination mode, interferences are successfully removed for the analysis of Cr-52 ((ArC)-Ar-40-C-12 and (ClOH)-Cl-35-O-16-H-1) and Ni-60 ((CaO)-Ca-44-O-16). The limits of detection are 0.162 mu g L-1 Cr and 0.248 mu g L-1 Ni. Method accuracy using NIST SRM 2668 level 1 (1.08 mu g L-1 Cr and 2.31 mu g L-1 Ni) and level 2 (27.7 mu g L-1 Cr and 115 mu g L-1 Ni) was within the 95% confidence intervals reported in the NIST certificate. Among-run precision is less than 10% RSDs (N = 20) for in house quality control and NIST SRM urine samples. While the limits of detection (LOD) for the new quadrupole ICP-UCT-MS with KED method are similar to the SF-ICP-MS method, better measurement precision is observed for the quadrupole method. The new method presented provides fast, accurate, and more precise results on a less complex and more robust ICP-MS platform.
C1 [Quarles, C. Derrick, Jr.; Jones, Deanna R.; Jarrett, Jeffery M.; Shakirova, Gulchekhra; Pan, Yi; Caldwell, Kathleen L.; Jones, Robert L.] Ctr Dis Control & Prevent, Inorgan & Radiat Analyt Toxicol Branch, Natl Ctr Environm Hlth, Atlanta, GA 30341 USA.
RP Quarles, CD (reprint author), Ctr Dis Control & Prevent, Inorgan & Radiat Analyt Toxicol Branch, Natl Ctr Environm Hlth, 4770 Buford Highway,Mailstop F-18, Atlanta, GA 30341 USA.
EM dquarles@appliedspectra.com
OI Jarrett, Jeffery/0000-0001-5755-3552
NR 26
TC 4
Z9 4
U1 2
U2 22
PU ROYAL SOC CHEMISTRY
PI CAMBRIDGE
PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS,
ENGLAND
SN 0267-9477
EI 1364-5544
J9 J ANAL ATOM SPECTROM
JI J. Anal. At. Spectrom.
PY 2014
VL 29
IS 2
BP 297
EP 303
DI 10.1039/c3ja50272d
PG 7
WC Chemistry, Analytical; Spectroscopy
SC Chemistry; Spectroscopy
GA 292WS
UT WOS:000329934000010
ER
PT J
AU Agaku, IT
King, BA
Dube, SR
AF Agaku, Israel T.
King, Brian A.
Dube, Shanta R.
TI Trends in exposure to pro-tobacco advertisements over the Internet, in
newspapers/magazines, and at retail stores among US middle and high
school students, 2000-2012
SO PREVENTIVE MEDICINE
LA English
DT Article
DE Advertising; School; Smoking; Prevalence; Tobacco; Health promotion;
Youths
ID NEIGHBORHOODS; INDUSTRY; HEALTH
AB Background. Most tobacco use begins during youth. Thus, this study assessed the prevalence, trends, and correlates of pro-tobacco advertising among United States students in grades 6-12 during 2000-2012.
Methods. Data from the 2000-2012 National Youth Tobacco Survey were analyzed to assess self-reported exposure to pro-tobacco advertisements through three media: over the Internet, in newspapers/magazines, and at retail stores. Trends during 2000-2012 were assessed in a binary logistic regression model (P < 0.05).
Results. Among all middle and high school students, the overall prevalence of exposure to Internet pro-tobacco advertisements increased from 22.3% to 43.0% during 2000-2012 (P < 0.001 for linear trend). During the same period, declines were observed in the overall prevalence of exposure to pro-tobacco advertisements in newspapers/magazines (65.0% to 36.9%) and at retail stores (87.8% to 76.2%) (P < 0.001 for all linear trends).
Conclusion. Exposure to pro-tobacco advertisements over the Internet increased significantly during 2000-2012 among United States middle and high school students, while a decline in exposure to advertisements in newspapers or magazines, and at retail stores occurred during the same period. However, over two-thirds of students still reported retail store exposure to pro-tobacco advertisements in 2012. Enhanced and sustained efforts would be beneficial to reduce even more exposure to all forms of pro-tobacco advertisements among youths. Published by Elsevier Inc.
C1 [Agaku, Israel T.; King, Brian A.; Dube, Shanta R.] Ctr Dis Control & Prevent, Off Smoking & Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30341 USA.
[Agaku, Israel T.] Ctr Dis Control & Prevent, Epidem Intelligence Serv, Div Appl Sci, Sci Educ & Profess Dev Program Off, Atlanta, GA 30341 USA.
RP Agaku, IT (reprint author), Ctr Dis Control & Prevent, Off Smoking & Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, CDC, 4770 Buford Highway,MS K-50, Atlanta, GA 30341 USA.
EM iagaku@cdc.gov; baking@cdc.gov; skd7@cdc.gov
NR 27
TC 4
Z9 4
U1 0
U2 8
PU ACADEMIC PRESS INC ELSEVIER SCIENCE
PI SAN DIEGO
PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA
SN 0091-7435
EI 1096-0260
J9 PREV MED
JI Prev. Med.
PD JAN
PY 2014
VL 58
BP 45
EP 52
DI 10.1016/j.ypmed.2013.10.012
PG 8
WC Public, Environmental & Occupational Health; Medicine, General &
Internal
SC Public, Environmental & Occupational Health; General & Internal Medicine
GA 295AL
UT WOS:000330088900007
PM 24183778
ER
PT J
AU Ghandour, RM
Hirai, AH
Blumberg, SJ
Strickland, BB
Kogan, MD
AF Ghandour, Reem M.
Hirai, Ashley H.
Blumberg, Stephen J.
Strickland, Bonnie B.
Kogan, Michael D.
TI Financial and Nonfinancial Burden Among Families of CSHCN: Changes
Between 2001 and 2009-2010
SO ACADEMIC PEDIATRICS
LA English
DT Article
DE children with special health care needs; family burden; financial
burden; trends
ID HEALTH-CARE NEEDS; NATIONAL PROFILE; UNITED-STATES; CHILDREN;
EXPENDITURES; IMPACT; DISABILITY; DISORDERS; CHILDHOOD; ACCESS
AB OBJECTIVE: We use the latest data to explore multiple dimensions of financial burden among children with special health care needs (CSHCN) and their families in 2009-2010 and changes since 2001.
METHODS: Five burden indicators were assessed using the 2001 and 2009-2010 National Surveys of CSHCN: past-year health-related out-of-pocket expenses of >=$1,000 or >= 3% of household income; perceived financial problems; changes in family employment; and >10 hours of weekly care provision/coordination. Unadjusted and adjusted prevalence estimates were used to assess burden in 2009-2010 and calculate absolute and relative measures of change since 2001. Prevalence rate ratios for each burden type in 2009-2010 compared to 2001 were estimated by logistic regression.
RESULTS: Nearly half of CSHCN and their families experienced some form of burden in 2009-2010. The percentage of CSHCN living in families that paid >=$1,000 or >= 3% of house-hold income out of pocket for health care rose 120% and 35%, respectively, between 2001 and 2009-2010, while the prevalence of caregiving and employment burdens declined. Relative to 2001, in 2009-2010, CSHCN who were privately insured or least affected by their conditions were 1.7 times as likely to live in families that paid >= 3% of household income out of pocket, while publicly insured children were 20% less likely to do so and those most severely affected were 12% more likely to do so.
CONCLUSIONS: Over the past decade, increases in financial burden and declines in employment and caregiving burdens were observed for CSHCN families. Public insurance expansions may have buffered increases in financial burden, yet disparities persist.
C1 [Ghandour, Reem M.; Hirai, Ashley H.; Kogan, Michael D.] Hlth Resources & Serv Adm, Off Epidemiol & Res, Maternal & Child Hlth Bur, US Dept Hlth & Human Serv, Rockville, MD 20857 USA.
[Blumberg, Stephen J.] Ctr Dis Control & Prevent, Natl Ctr Hlth Stat, US Dept Hlth & Human Serv, Div Hlth Interview Stat, Hyattsville, MD 20782 USA.
[Strickland, Bonnie B.] Hlth Resources & Serv Adm, US Dept Hlth & Human Serv, Maternal & Child Hlth Bur, Div Serv Children Special Hlth Care Needs, Rockville, MD 20857 USA.
RP Ghandour, RM (reprint author), Hlth Resources & Serv Adm, Off Epidemiol & Res, Maternal & Child Hlth Bur, US Dept Hlth & Human Serv, 5600 Fishers Ln,Room 18-41, Rockville, MD 20857 USA.
EM rghandour@hrsa.gov
FU Intramural CDC HHS [CC999999]
NR 35
TC 9
Z9 9
U1 2
U2 3
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1876-2859
EI 1876-2867
J9 ACAD PEDIATR
JI Acad. Pediatr.
PD JAN-FEB
PY 2014
VL 14
IS 1
BP 92
EP 100
PG 9
WC Pediatrics
SC Pediatrics
GA 287SS
UT WOS:000329563100015
PM 24369874
ER
PT J
AU Caraballo, RS
Kruger, J
Asman, K
Pederson, L
Widome, R
Kiefe, CI
Hitsman, B
Jacobs, DR
AF Caraballo, Ralph S.
Kruger, Judy
Asman, Kat
Pederson, Linda
Widome, Rachel
Kiefe, Catarina I.
Hitsman, Brian
Jacobs, David R., Jr.
TI Relapse among Cigarette Smokers: The CARDIA longitudinal study-1985-2011
SO ADDICTIVE BEHAVIORS
LA English
DT Article
DE Relapse; Cessation; Cigarette; Smoking; Abstinence
ID SMOKING-CESSATION; TRAJECTORIES; DEPENDENCE; RISK; US
AB Rationale: There is little information about long-term relapse patterns for cigarette smokers.
Objective: To describe long-term prevalence of relapse and related smoking patterns by sex, race, age, and education level among a community-based cohort of young adults followed for 25 years.
Methods: We examined 25 years of data from Coronary Artery Risk Development in Young Adults (CARDIA), an ongoing study of a community-based cohort of 5115 men and women aged 18 to 30 years at baseline with periodic re-examinations. At each examination smoking, quitting, and relapse were queried. We examined prevalence of smoking relapse among 3603 participants who attended at least 6 of the 8 examinations.
Results: About 53% of 3603 participants never reported smoking on a regular basis. Among the remaining 1682 ever smokers, 52.8% of those who reported current smoking at baseline were still smoking by the end of the study, compared to 10.7% of those who initiated smoking by year 5. Among those classified as former smokers at baseline, 39% relapsed at least once; of these, 69.5% had quit again by the end of the study. Maximum education level attained, age at study baseline, and race were associated with failure to quit smoking by the end of the study and relapse among those who did quit Maximum education level attained and age at study baseline were also associated with ability to successfully quit after a relapse.
Conclusions: Smoking relapse after quitting is common, especially in those with lower education level. Education was the strongest predictor of all three outcomes. Improvements in access to treatment and treatment options, especially for underserved populations, are needed to prevent relapse when smokers quit. Published by Elsevier Ltd.
C1 [Caraballo, Ralph S.; Kruger, Judy] Natl Ctr Chron Dis Prevent & Hlth Promot, Off Smoking & Hlth, Epidemiol Branch, Atlanta, GA 30341 USA.
[Asman, Kat; Pederson, Linda] RTI Int, Stat & Epidemiol Unit, Atlanta, GA 30341 USA.
[Pederson, Linda] McKing Consulting Corp, Atlanta, GA 30341 USA.
[Widome, Rachel; Jacobs, David R., Jr.] Univ Minnesota, Div Epidemiol & Community Hlth, Sch Publ Hlth, Minneapolis, MN 55454 USA.
[Kiefe, Catarina I.] Univ Massachusetts, Sch Med, Dept Quantitat Hlth Sci, Worcester, MA 01655 USA.
[Hitsman, Brian] Northwestern Univ, Feinberg Sch Med, Dept Prevent Med, Chicago, IL 60611 USA.
RP Caraballo, RS (reprint author), Off Smoking & Hlth, Epidemiol Branch, 4770 Buford Highway,M-S K-50, Atlanta, GA 30341 USA.
EM rfc8@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 28
TC 9
Z9 9
U1 1
U2 12
PU PERGAMON-ELSEVIER SCIENCE LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
SN 0306-4603
EI 1873-6327
J9 ADDICT BEHAV
JI Addict. Behav.
PD JAN
PY 2014
VL 39
IS 1
BP 101
EP 106
DI 10.1016/j.addbeh.2013.08.030
PG 6
WC Psychology, Clinical; Substance Abuse
SC Psychology; Substance Abuse
GA 287RQ
UT WOS:000329560300013
PM 24172753
ER
PT J
AU Diallo, K
Lehotzky, E
Zhang, J
Zhou, ZY
de Rivera, IL
Murillo, WE
Nkengasong, J
Sabatier, J
Zhang, GQ
Yang, CF
AF Diallo, Karidia
Lehotzky, Erica
Zhang, Jing
Zhou, Zhiyong
de Rivera, Ivette Lorenzana
Murillo, Wendy E.
Nkengasong, John
Sabatier, Jennifer
Zhang, Guoqing
Yang, Chunfu
TI Evaluation of a Dried Blood and Plasma Collection Device, SampleTanker
(R), for HIV Type 1 Drug Resistance Genotyping in Patients Receiving
Antiretroviral Therapy
SO AIDS RESEARCH AND HUMAN RETROVIRUSES
LA English
DT Article
ID HUMAN-IMMUNODEFICIENCY-VIRUS; SPOT SPECIMENS; FILTER PAPERS; RNA; ASSAY;
EXTRACTION; DIAGNOSIS; DATABASE; INFANTS; STORAGE
AB Whatman 903 filter paper is the only filter paper that has been used for HIV drug resistance (HIVDR) genotyping in resource-limited settings. In this study, we evaluated another dried blood specimen collection device, termed SampleTanker((R)) (ST), for HIVDR genotyping. Blood specimens from 123 antiretroviral therapy (ART)-experienced patients were used to prepare ST whole blood and ST plasma specimens; they were then stored at ambient temperature for 2 or 4 weeks. The remaining plasma specimens were stored at -80 degrees C and used as frozen plasma controls. Frozen plasma viral load (VL) was determined using the Roche Amplicor HIV-1 Monitor test, v.1.5 and 50 specimens with VL 3.00 log(10) copies/ml were genotyped using the broadly sensitive genotyping assay. The medium VL for the 50 frozen plasma specimens with VL 3.00 log(10) was 3.58 log(10) copies/ml (IQR: 3.32-4.11) and 96.0% (48/50) of them were genotyped. Comparing to frozen plasma specimens, significantly lower genotyping rates were obtained from ST whole blood (48.98% and 42.85%) and ST plasma specimens (36.0% and 36.0%) stored at ambient temperature for 2 and 4 weeks, respectively (p<0.001). Nucleotide sequence identity and resistance profile analyses between the matched frozen plasma and ST whole blood or ST plasma specimens revealed high nucleotide sequence identities and concordant resistance profiles (98.1% and 99.0%, and 96.6% and 98.9%, respectively). Our results indicate that with the current design, the ST may not be the ideal dried blood specimen collection device for HIVDR monitoring for ART patients in resource-limited settings.
C1 [Diallo, Karidia; Lehotzky, Erica; Zhang, Jing; Zhou, Zhiyong; Nkengasong, John; Zhang, Guoqing; Yang, Chunfu] Ctr Dis Control & Prevent, Int Lab Branch, Div Global HIV AIDS, CGH, Atlanta, GA 30333 USA.
[de Rivera, Ivette Lorenzana; Murillo, Wendy E.] UNAH, Tegucigalpa, Honduras.
[Sabatier, Jennifer] Ctr Dis Control & Prevent, Strateg Informat & Epidemiol Branch, Div Global HIV AIDS, CGH, Atlanta, GA 30333 USA.
RP Yang, CF (reprint author), Ctr Dis Control & Prevent, Int Lab Branch, Div Global HIV AIDS, CGH, Mail Stop A-11,1600 Clifton Rd NE, Atlanta, GA 30333 USA.
EM cyang1@cdc.gov
RI Zhang, Guoqing/C-9523-2014; Yang, Chunfu/G-6890-2013
FU American Public Health Laboratory (APHL); CDC; Centers for Disease
Control and Prevention
FX Dr. Guoqing Zhang was a recipient of the 2010-2011 International
Emerging Infectious Fellowship (IEID) sponsored by the American Public
Health Laboratory (APHL) and CDC. This research has been supported by
the President's Emergency Plan for AIDS Relief (PEPFAR) through the
Centers for Disease Control and Prevention.
NR 30
TC 4
Z9 4
U1 0
U2 2
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 0889-2229
EI 1931-8405
J9 AIDS RES HUM RETROV
JI Aids Res. Hum. Retrovir.
PD JAN 1
PY 2014
VL 30
IS 1
BP 67
EP 73
DI 10.1089/aid.2013.0127
PG 7
WC Immunology; Infectious Diseases; Virology
SC Immunology; Infectious Diseases; Virology
GA 284BO
UT WOS:000329291200012
PM 23944768
ER
PT J
AU Shvedova, AA
Yanamala, N
Kisin, ER
Tkach, AV
Murray, AR
Hubbs, A
Chirila, MM
Keohavong, P
Sycheva, LP
Kagan, VE
Castranova, V
AF Shvedova, Anna A.
Yanamala, Naveena
Kisin, Elena R.
Tkach, Alexey V.
Murray, Ashley R.
Hubbs, Ann
Chirila, Madalina M.
Keohavong, Phouthone
Sycheva, Lyudmila P.
Kagan, Valerian E.
Castranova, Vincent
TI Long-term effects of carbon containing engineered nanomaterials and
asbestos in the lung: one year postexposure comparisons
SO AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
LA English
DT Article
DE nanoparticles; long-term postexposure; inflammation; fibrosis;
genotoxicity
ID HUMAN MESOTHELIAL CELLS; NF-KAPPA-B; TUMOR-SUPPRESSOR; EPITHELIAL-CELLS;
MOUSE LUNG; IN-VITRO; CYSTEINE CATHEPSINS; GLUCOSE-METABOLISM; PROTEOME
ANALYSIS; OXIDATIVE STRESS
AB The hallmark geometric feature of single-walled carbon nanotubes (SWCNT) and carbon nanofibers (CNF), high length to width ratio, makes them similar to a hazardous agent, asbestos. Very limited data are available concerning long-term effects of pulmonary exposure to SWCNT or CNF. Here, we compared inflammatory, fibrogenic, and genotoxic effects of CNF, SWCNT, or asbestos in mice 1 yr after pharyngeal aspiration. In addition, we compared pulmonary responses to SWCNT by bolus dosing through pharyngeal aspiration and inhalation 5 h/day for 4 days, to evaluate the effect of dose rate. The aspiration studies showed that these particles can be visualized in the lung at 1 yr postexposure, whereas some translocate to lymphatics. All these particles induced chronic bronchopneumonia and lymphadenitis, accompanied by pulmonary fibrosis. CNF and asbestos were found to promote the greatest degree of inflammation, followed by SWCNT, whereas SWCNT were the most fibrogenic of these three particles. Furthermore, SWCNT induced cytogenetic alterations seen as micronuclei formation and nuclear protrusions in vivo. Importantly, inhalation exposure to SWCNT showed significantly greater inflammatory, fibrotic, and genotoxic effects than bolus pharyngeal aspiration. Finally, SWCNT and CNF, but not asbestos exposures, increased the incidence of K-ras oncogene mutations in the lung. No increased lung tumor incidence occurred after 1 yr postexposure to SWCNT, CNF, and asbestos. Overall, our data suggest that long-term pulmonary toxicity of SWCNT, CNF, and asbestos is defined, not only by their chemical composition, but also by the specific surface area and type of exposure.
C1 [Shvedova, Anna A.; Yanamala, Naveena; Kisin, Elena R.; Tkach, Alexey V.; Murray, Ashley R.; Hubbs, Ann; Chirila, Madalina M.; Castranova, Vincent] NIOSH, CDC, Morgantown, WV 26505 USA.
[Keohavong, Phouthone; Kagan, Valerian E.] Univ Pittsburgh, Pittsburgh, PA USA.
[Sycheva, Lyudmila P.] Sysin Res Inst Human Ecol & Environm, Moscow, Russia.
RP Shvedova, AA (reprint author), NIOSH, CDC, 1095 Willowdale Rd, Morgantown, WV 26505 USA.
EM ats1@cdc.gov
OI Keohavong, Phouthone/0000-0001-7812-4925; Sycheva,
Lyudmila/0000-0002-7370-0169
FU NTRC Grant [3927ZJHF]; NIOSH Grant [OH008282]; NIH [R01 ES-019304,
HL-070755, U19 AI-068021]
FX This work was supported by NTRC Grant 3927ZJHF (A. Shvedova), NIOSH
Grant OH008282, and NIH Grants R01 ES-019304, HL-070755, and U19
AI-068021 (V. Kagan).
NR 85
TC 32
Z9 33
U1 0
U2 20
PU AMER PHYSIOLOGICAL SOC
PI BETHESDA
PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 USA
SN 1040-0605
EI 1522-1504
J9 AM J PHYSIOL-LUNG C
JI Am. J. Physiol.-Lung Cell. Mol. Physiol.
PD JAN
PY 2014
VL 306
IS 2
BP L170
EP L182
DI 10.1152/ajplung.00167.2013
PG 13
WC Physiology; Respiratory System
SC Physiology; Respiratory System
GA 291VC
UT WOS:000329858000007
PM 24213921
ER
PT J
AU Eberhard, ML
Ruiz-Tiben, E
Hopkins, DR
Farrell, C
Toe, F
Weiss, A
Withers, PC
Jenks, MH
Thiele, EA
Cotton, JA
Hance, Z
Holroyd, N
Cama, VA
Tahir, MA
Mounda, T
AF Eberhard, Mark L.
Ruiz-Tiben, Ernesto
Hopkins, Donald R.
Farrell, Corey
Toe, Fernand
Weiss, Adam
Withers, P. Craig, Jr.
Jenks, M. Harley
Thiele, Elizabeth A.
Cotton, James A.
Hance, Zahra
Holroyd, Nancy
Cama, Vitaliano A.
Tahir, Mahamat Ali
Mounda, Tchonfienet
TI The Peculiar Epidemiology of Dracunculiasis in Chad
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Article
ID DNA-SEQUENCING DATA; 18S RIBOSOMAL-RNA; GENOME; ERADICATION; MEDINENSIS;
DISCOVERY; FRAMEWORK; INSIGNIS
AB Dracunculiasis was rediscovered in Chad in 2010 after an apparent absence of 10 years. In April 2012 active village-based surveillance was initiated to determine where, when, and how transmission of the disease was occurring, and to implement interventions to interrupt it. The current epidemiologic pattern of the disease in Chad is unlike that seen previously in Chad or other endemic countries, i.e., no clustering of cases by village or association with a common water source, the average number of worms per person was small, and a large number of dogs were found to be infected. Molecular sequencing suggests these infections were all caused by Dracunculus medinensis. It appears that the infection in dogs is serving as the major driving force sustaining transmission in Chad, that an aberrant life cycle involving a paratenic host common to people and dogs is occurring, and that the cases in humans are sporadic and incidental.
C1 Ctr Dis Control & Prevent, Div Parasit Dis & Malaria, Atlanta, GA USA.
[Ruiz-Tiben, Ernesto; Hopkins, Donald R.; Weiss, Adam; Withers, P. Craig, Jr.] Emory Univ, Carter Ctr, Atlanta, GA 30322 USA.
[Farrell, Corey; Toe, Fernand] Carter Ctr, Ndjamena, Chad.
LifeSource Biomed, Centreville, VA USA.
Wellcome Trust Sanger Inst, Hinxton, England.
[Tahir, Mahamat Ali; Mounda, Tchonfienet] Minist Publ Hlth, Ndjamena, Chad.
[Eberhard, Mark L.; Jenks, M. Harley; Thiele, Elizabeth A.; Cama, Vitaliano A.] CDC, Div Parasit Dis, Atlanta, GA 30333 USA.
[Cotton, James A.; Hance, Zahra; Holroyd, Nancy] Wellcome Trust Sanger Inst, Cambridge, England.
RP Eberhard, ML (reprint author), CDC, Div Parasit Dis & Malaria, 1600 Clifton Rd, Atlanta, GA 30333 USA.
EM meberhard@cdc.gov; eruizti@emory.edu; sdsulli@emory.edu;
clfarrel12@gmail.com; fernandtoe@gmail.com; adam.j.weiss@emory.edu;
cwither@emory.edu; uwq1@cdc.gov; xas4@cdc.gov;
james.cotton@sanger.ac.uk; za1@sanger.ac.uk; neh@sanger.ac.uk;
vcama@cdc.gov; mahamat_tahir2@yahoo.fr; tchomcalvin@yahoo.fr
RI Cotton, James/B-8806-2008; Thiele, Elizabeth/F-2590-2016
OI Cotton, James/0000-0001-5475-3583; Thiele, Elizabeth/0000-0001-9235-2019
FU NTD Department; WHO; Next Generation Fund of the Hugh J. Andersen
Foundation; Apple Computer, Inc.; Arab Fund for Economic and Social
Development; Atlanta Woman's Club; BASF Corporation; Canadian
International Development Agency; Chevron Corporation; Children's
Investment Fund Foundation UK; Crawford Family Foundation; Delta Medical
Supplies; Edgar O. Dixon Charitable Trust; Elfenworks Foundation; First
Congregational Church; Foundation Source; Bill & Melinda Gates
Foundation; General Electric Company; Girl Scouts of America Brownie
Troop 861; Global Aviation Holdings; Global Health Education Consortium,
Inc.; Google, Inc.; Robert and Shirley Harris Family Foundation; Harris
myCFO Foundation; Conrad N. Hilton Foundation; John C. and Karyl Kay
Hughes Foundation; John P. Hussman Foundation, Inc.; Johns Hopkins
University; Johnson Johnson; Kendeda Fund; Leslie Family Foundation;
John D. and Catherine T. MacArthur Foundation; McKenna Foundation;
Mid-Continent University; Monsanto Company; Mount Pleasant Lutheran
Church; National Democratic Institute for International Affairs; OPEC
Fund for International Development; Roman Catholic Diocese of Joliet;
Government of Saudi Arabia; Saudi Fund for Development; JV Schiro Zavela
Foundation; S.H.O.D. LLC; Stahl Family Foundation; St. Thomas Aquinas
Parish; Sultanate of Oman: HH General Sheikh Mohamed bin Zayed Al
Nahyan, Crown Prince of Abu Dhabi, in honor of HH Sheikh Khalifa bin
Zayed, President of the United Arab Emirates; UNICEF; UNICEF; United
Kingdom Department for International Development; U.S. Agency for
International Development; U.S. Centers for Disease Control and
Prevention; United Nations World Food Programme; Vanguard Charitable
Endowment Program; Vestergaard Frandsen; Women's Leadership Foundation;
YKK Corporation; Wellcome Trust [098051]
FX The Parasitic Diseases Branch, Division of Parasitic Diseases, CDC,
serves as a WHO Collaborating Center on Dracunculiasis Eradication, and
as such, received a small award from the NTD Department, WHO, in support
of these activities. During 2008 2012, The Carter Center's work to
eradicate Guinea worm disease has been made possible by financial and
in-kind contributions from Next Generation Fund of the Hugh J. Andersen
Foundation; Apple Computer, Inc.; Arab Fund for Economic and Social
Development; Atlanta Woman's Club; BASF Corporation; Canadian
International Development Agency; Chevron Corporation; Children's
Investment Fund Foundation UK; Crawford Family Foundation; Delta Medical
Supplies; Edgar O. Dixon Charitable Trust; Elfenworks Foundation; First
Congregational Church;. Foundation Source; Bill & Melinda Gates
Foundation; General Electric Company; Girl Scouts of America Brownie
Troop 861; Global Aviation Holdings; Global Health Education Consortium,
Inc.: Google, Inc.; Robert and Shirley Harris Family Foundation; Harris
myCFO Foundation; Conrad N. Hilton Foundation; John C. and Karyl Kay
Hughes Foundation; John P. Hussman Foundation, Inc.; Johns Hopkins
University; Johnson & Johnson; Kendeda Fund; Leslie Family Foundation;
John D. and Catherine T. MacArthur Foundation; McKenna Foundation;
Mid-Continent University: Monsanto Company; Mount Pleasant Lutheran
Church: National Democratic Institute for International Affairs: OPEC
Fund for International Development; Roman Catholic Diocese of Joliet;
Government of Saudi Arabia; Saudi Fund for Development; JV Schiro Zavela
Foundation; S.H.O.D. LLC; Stahl Family Foundation; St. Thomas Aquinas
Parish; Sultanate of Oman: HH General Sheikh Mohamed bin Zayed Al
Nahyan, Crown Prince of Abu Dhabi, in honor of HH Sheikh Khalifa bin
Zayed, President of the United Arab Emirates; UNICEF; United Kingdom
Department for International Development; U.S. Agency for International
Development; U.S. Centers for Disease Control and Prevention; United
Nations World Food Programme; Vanguard Charitable Endowment Program;
Vestergaard Frandsen; Women's Leadership Foundation; YKK Corporation;
and many generous individuals. The Wellcome Trust Sanger Institute is
supported by the Wellcome Trust through grant 098051.
NR 19
TC 24
Z9 24
U1 3
U2 31
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
EI 1476-1645
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD JAN
PY 2014
VL 90
IS 1
BP 61
EP 70
DI 10.4269/ajtmh.13-0554
PG 10
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 288BO
UT WOS:000329587200012
PM 24277785
ER
PT J
AU Eddy, BA
Blackstock, AJ
Williamson, JM
Addiss, DG
Streit, TG
de Rochars, VMB
Fox, LM
AF Eddy, Brittany A.
Blackstock, Anna J.
Williamson, John M.
Addiss, David G.
Streit, Thomas G.
de Rochars, Valery M. Beau
Fox, LeAnne M.
TI A Longitudinal Analysis of the Effect of Mass Drug Administration on
Acute Inflammatory Episodes and Disease Progression in Lymphedema
Patients in Leogane, Haiti
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Article
ID PREVENTING ACUTE ADENOLYMPHANGITIS; ELIMINATE LYMPHATIC FILARIASIS;
BRUGIA-MALAYI INFECTION; PAPUA-NEW-GUINEA; BANCROFTIAN FILARIASIS;
WUCHERERIA-BANCROFTI; AFFECTED-LIMB; DIETHYLCARBAMAZINE CHEMOTHERAPY;
CLINICAL MANIFESTATIONS; COMPARATIVE EFFICACY
AB We conducted a longitudinal analysis of 117 lymphedema patients in a filariasis-endemic area of Haiti during 1995-2008. No difference in lymphedema progression between those who received or did not receive mass drug administration (MDA) was found on measures of foot (P = 0.24), ankle (P = 0.87), or leg (P = 0.46) circumference; leg volume displacement (P = 0.09), lymphedema stage (P = 0.93), or frequency of adenolymphangitis (ADL) episodes (P = 0.57). Rates of ADL per year were greater after initiation of MDA among both groups (P < 0.01). Nevertheless, patients who received MDA reported improvement in four areas of lymphedema-related quality of life (P <= 0.01). Decreases in foot and ankle circumference and ADL episodes were observed during the 1995-1998 lymphedema management study (P <= 0.01). This study represents the first longitudinal, quantitative, leg-specific analysis examining the clinical effect of diethylcarbamazine on lymphedema progression and ADL episodes.
C1 Emory Univ, Rollins Sch Publ Hlth, Dept Epidemiol, Atlanta, GA 30322 USA.
Ctr Dis Control & Prevent, Div Parasit Dis & Malaria, Ctr Global Hlth, Atlanta, GA 30333 USA.
Atlanta Res & Educ Fdn, Decatur, GA USA.
[Addiss, David G.] Task Force Global Hlth, Children Worms, Decatur, GA USA.
[Streit, Thomas G.] Univ Notre Dame, Ctr Trop Dis Res & Training, Notre Dame, IN 46556 USA.
Hop St Croix, Lymphat Filariasis Program, Leogane, Haiti.
[Eddy, Brittany A.] Partners Hlth, Boston, MA USA.
[Blackstock, Anna J.; Fox, LeAnne M.] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
[Williamson, John M.] Kenya Govt Med Res Ctr, Ctr Global Hlth Res, Ctr Dis Control & Prevent, Kisian Kisumu, Kenya.
[de Rochars, Valery M. Beau] Univ Florida, Dept Hlth Serv Res Management & Policy, Gainesville, FL USA.
RP Fox, LM (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd NE,Mailstop A-06, Atlanta, GA 30333 USA.
EM beddy@pih.org; ablackstock@cdc.gov; jwilliamson@ke.cdc.gov;
daddiss@taskforce.org; streit1@nd.edu; madsenbeau@phhp.ufl.edu;
lfox@cdc.gov
FU University of Notre Dame Haiti Program; Bill and Melinda Gates
Foundation; Fogarty International Center [5 R25 TW7733]; National
Institutes of Health; Centers for Disease Control and Prevention
FX This study was supported by The University of Notre Dame Haiti Program
with funding by the Bill and Melinda Gates Foundation; the Framework in
Global Health (grant 5 R25 TW7733) to Emory University from the Fogarty
International Center, National Institutes of Health; and the Centers for
Disease Control and Prevention.
NR 52
TC 2
Z9 2
U1 0
U2 2
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
EI 1476-1645
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD JAN
PY 2014
VL 90
IS 1
BP 80
EP 88
DI 10.4269/ajtmh.13-0317
PG 9
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 288BO
UT WOS:000329587200015
PM 24218408
ER
PT J
AU Budge, PJ
Dorkenoo, AM
Sodahlon, YK
Fasuyi, OB
Mathieu, E
AF Budge, Philip J.
Dorkenoo, Ameyo M.
Sodahlon, Yao K.
Fasuyi, Omofolarin B.
Mathieu, Els
TI Ongoing Surveillance for Lymphatic Filariasis in Togo: Assessment of
Alternatives and Nationwide Reassessment of Transmission Status
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Article
ID SLEEPING-SICKNESS; BANCROFTIAN FILARIASIS; RAPID ASSESSMENT; MALARIA;
ERADICATION; ELIMINATION; PROSPECTS; PROGRESS; LESSONS; STORY
AB Tremendous progress has been made towards the goal of global elimination of lymphatic filariasis (LF) transmission by 2020. The number of endemic countries reducing LF transmission through mass drug administration continues to increase, and therefore, the need for effective post-intervention surveillance also continues to increase. Togo is the first sub-Saharan African country to implement LF surveillance, and it has 6 years of experience with this passive surveillance system. We herein report the results of a recent evaluation of the Togolese LF surveillance system, including an evaluation of blood donors as a surveillance population, and provide updated results of ongoing surveillance, including expansion in remote areas. Since implementation of LF surveillance in 2006, only three cases of positive Wuchereria bancrofti filaremia have been detected, suggesting that interruption of transmission has been sustained. Given the impracticality of validating the surveillance system in the absence of ongoing transmission, we confirmed the lack of transmission through a nationwide reassessment survey.
C1 Ctr Dis Control & Prevent, Epidem Intelligence Serv Assigned Parasit Dis Bra, Div Parasit Dis & Malaria, Atlanta, GA 30333 USA.
[Dorkenoo, Ameyo M.] Minist Hlth, Program Eliminat Lymphat Filariasis, Lome, Togo.
Mectizan Donat Program, Atlanta, GA USA.
Emory Univ, Rollins Sch Publ Hlth, Dept Hlth Policy & Management, Atlanta, GA 30322 USA.
Ctr Dis Control & Prevent, Parasit Dis Branch, Div Parasit Dis & Malaria, Atlanta, GA 30333 USA.
[Budge, Philip J.] Vanderbilt Univ, Med Ctr, Div Infect Dis, Nashville, TN USA.
[Sodahlon, Yao K.] Mectizan Donat Program, Decatur, GA USA.
[Fasuyi, Omofolarin B.] Morehouse Sch Med, Dept Family Med, East Point, GA USA.
[Mathieu, Els] Ctr Dis Control & Prevent, Div Parasit Dis & Malaria, Atlanta, GA 30333 USA.
RP Mathieu, E (reprint author), Ctr Dis Control & Prevent, Ctr Global Hlth, 1600 Clifton Rd, Atlanta, GA 30333 USA.
EM Philip.budge@vanderbilt.edu; monicadork@yahoo.fr;
ysodahlon@taskforce.org; OFasuyi@msm.edu; emm7@cdc.gov
FU U.S. Agency for International Development (USAID); ENVISION
[AID-OAA-A-11-00048]
FX This study is made possible by the generous support of the American
people through the U.S. Agency for International Development (USAID) and
the ENVISION project under cooperative agreement No. AID-OAA-A-11-00048.
NR 25
TC 3
Z9 3
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
EI 1476-1645
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD JAN
PY 2014
VL 90
IS 1
BP 89
EP 95
DI 10.4269/ajtmh.13-0407
PG 7
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 288BO
UT WOS:000329587200016
PM 24189363
ER
PT J
AU Lindsey, NP
Staples, JE
Delorey, MJ
Fischer, M
AF Lindsey, Nicole P.
Staples, J. Erin
Delorey, Mark J.
Fischer, Marc
TI Lack of Evidence of Increased West Nile Virus Disease Severity in the
United States in 2012
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Article
ID RISK-FACTORS; ARBOVIRAL DISEASES; INFECTION; ENCEPHALITIS; OUTBREAK;
EPIDEMIC; COLORADO; REGION; USA
AB In the United States, West Nile virus (WNV) causes annual seasonal outbreaks that fluctuate in size and scope. There was a large multistate outbreak of WNV in 2012, with more human disease cases reported nationally than any year since 2003. We evaluated national surveillance data to determine if the higher number of WNV cases reported in 2012 was associated with changes in the epidemiology or severity of disease compared with 2004-2011. Despite an increased incidence of neuroinvasive disease in 2012, national surveillance data showed no evidence of changes in epidemiology or increased disease severity compared with the previous 8 years.
C1 [Lindsey, Nicole P.; Staples, J. Erin; Delorey, Mark J.; Fischer, Marc] Ctr Dis Control & Prevent, Div Vector Borne Dis, Ft Collins, CO 80521 USA.
RP Lindsey, NP (reprint author), Ctr Dis Control & Prevent, Div Vector Borne Dis, 3156 Rampart Rd, Ft Collins, CO 80521 USA.
EM frd3@cdc.gov; auv1@cdc.gov; esy7@cdc.gov; mxf2@cdc.gov
FU Centers for Disease Control and Prevention
FX This work was funded by the Centers for Disease Control and Prevention.
NR 23
TC 7
Z9 7
U1 0
U2 3
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
EI 1476-1645
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD JAN
PY 2014
VL 90
IS 1
BP 163
EP 168
DI 10.4269/ajtmh.13-0432
PG 6
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 288BO
UT WOS:000329587200029
PM 24218412
ER
PT J
AU Bamrah, S
Desmond, E
Ghosh, S
France, AM
Kammerer, JS
Cowan, LS
Heetderks, A
Forbes, A
Moonan, PK
AF Bamrah, Sapna
Desmond, Edward
Ghosh, Smita
France, Anne Marie
Kammerer, J. Steve
Cowan, Lauren S.
Heetderks, Andrew
Forbes, Alstead
Moonan, Patrick K.
TI Molecular Epidemiology of Mycobacterium tuberculosis in the United
States-Affiliated Pacific Islands
SO ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH
LA English
DT Article
DE genotype; molecular epidemiology; Pacific Islands (trust territory);
tuberculosis
ID MULTIDRUG-RESISTANT TUBERCULOSIS; DIAGNOSIS; OUTBREAK
AB The United States-Affiliated Pacific Islands (USAPI) are part of the US National Tuberculosis (TB) Surveillance System and use laboratory services contracted through a cooperative agreement with the Centers for Disease Control and Prevention (CDC). In 2004, the CDC established the National Tuberculosis Genotyping Service, a system to genotype 1 isolate from each culture-confirmed case of TB. To describe the molecular epidemiology of TB in the region, we examined all Mycobacterium tuberculosis isolates submitted for genotyping from January 1, 2004, to December 31, 2008. Over this time period, the USAPI jurisdictions reported 1339 verified TB cases to the National Tuberculosis Surveillance System. Among 419 (31%) reported culture-confirmed TB cases, 352 (84%) had complete genotype results. Routine TB genotyping allowed, for the first time, an exploration of the molecular epidemiology of TB in the USAPI.
C1 [Bamrah, Sapna; Ghosh, Smita; France, Anne Marie; Kammerer, J. Steve; Cowan, Lauren S.; Heetderks, Andrew; Forbes, Alstead; Moonan, Patrick K.] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
[Desmond, Edward] State Calif Dept Publ Hlth Labs, Richmond, CA USA.
RP Bamrah, S (reprint author), Ctr Dis Control & Prevent, Div TB Eliminat, 1600 Clifton Rd,Mailstop E-10, Atlanta, GA 30333 USA.
EM sbamrah@cdc.gov
RI Moonan, Patrick/F-4307-2014;
OI Moonan, Patrick/0000-0002-3550-2065
NR 19
TC 0
Z9 0
U1 0
U2 2
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1010-5395
EI 1941-2479
J9 ASIA-PAC J PUBLIC HE
JI Asia-Pac. J. Public Health
PD JAN
PY 2014
VL 26
IS 1
BP 77
EP 84
DI 10.1177/1010539512469249
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 287MF
UT WOS:000329545200011
PM 23239749
ER
PT J
AU Schrader, SM
Marlow, KL
AF Schrader, Steven M.
Marlow, Katherine L.
TI Assessing the reproductive health of men with occupational exposures
SO ASIAN JOURNAL OF ANDROLOGY
LA English
DT Review
DE accessory glands; endocrine; epidemiology; semen; sexual function;
sperm; testis; toxicology
ID IN-SITU HYBRIDIZATION; MALE SEXUAL FUNCTION; NOCTURNAL PENILE
TUMESCENCE; SPERM CHROMATIN-STRUCTURE; MALE HORMONE PROFILE; SEMEN
QUALITY; LEAD-EXPOSURE; INHIBIN-B; AGRICULTURAL-WORKERS; REGIONAL
DIFFERENCES
AB The earliest report linking environmental (occupational) exposure to adverse human male reproductive effects dates back to1775 when an English physician, Percival Pott, reported a high incidence of scrotal cancer in chimney sweeps. This observation led to safety regulations in the form of bathing requirements for these workers. The fact that male-mediated reproductive harm in humans may be a result of toxicant exposures did not become firmly established until relatively recently, when Lancranjan studied lead-exposed workers in Romania in 1975, and later in 1977, when Whorton examined the effects of dibromochloropropane (DBCP) on male workers in California. Since these discoveries, several additional human reproductive toxicants have been identified through the convergence of laboratory and observational findings. Many research gaps remain, as the pool of potential human exposures with undetermined effects on male reproduction is vast. This review provides an overview of methods used to study the effects of exposures on male reproduction and their reproductive health, with a primary emphasis on the implementation and interpretation of human studies. Emphasis will be on occupational exposures, although much of the information is also useful in assessing environmental studies, occupational exposures are usually much higher and better defined.
C1 [Schrader, Steven M.] NIOSH, Ctr Dis Control, Div Appl Res & Technol, Cincinnati, OH 45226 USA.
[Schrader, Steven M.] NIOSH, Ctr Prevent, Div Appl Res & Technol, Cincinnati, OH 45226 USA.
RP Schrader, SM (reprint author), NIOSH, Ctr Dis Control, Div Appl Res & Technol, Cincinnati, OH 45226 USA.
EM sms4@cdc.gov
NR 128
TC 2
Z9 2
U1 4
U2 17
PU MEDKNOW PUBLICATIONS & MEDIA PVT LTD
PI MUMBAI
PA B-9, KANARA BUSINESS CENTRE, OFF LINK RD, GHAKTOPAR-E, MUMBAI, 400075,
INDIA
SN 1008-682X
EI 1745-7262
J9 ASIAN J ANDROL
JI Asian J. Androl.
PD JAN
PY 2014
VL 16
IS 1
BP 23
EP 30
DI 10.4103/1008-682X.122352
PG 8
WC Andrology; Urology & Nephrology
SC Endocrinology & Metabolism; Urology & Nephrology
GA 285QW
UT WOS:000329409700004
PM 24369130
ER
PT J
AU Kelly, NR
Harding, JT
Fulton, JE
Kozinetz, CA
AF Kelly, N. R.
Harding, J. T.
Fulton, J. E.
Kozinetz, C. A.
TI A randomized controlled trial of a video module to increase US poison
center use by low-income parents
SO CLINICAL TOXICOLOGY
LA English
DT Article
DE Poison prevention; Educational intervention; Community outreach
ID EXPOSURES; BARRIERS; CHILDREN; ASSOCIATION; VISITS; SYSTEM; TEXAS
AB Context. U.S. poison centers decrease medical visits by providing telephone advice for home management of potential poisonings, but are underutilized by low-income African-American and Latino parents, and those with limited English proficiency, due to lack of knowledge and misconceptions about poison centers. Objectives. To assess the effectiveness of a poison prevention video module in improving knowledge, behavior, and behavioral intention concerning use of poison centers in a population of low-income, language-diverse adults attending parenting courses offered by a community organization. Methods. A randomized, blinded, controlled trial was conducted at 16 parenting course sites of a community organization and included 297 participants. The organization's instructors presented the video module (intervention) or the usual class curriculum (control). Participants completed questionnaires at baseline and a telephone interview 2-4 weeks later. Changes from baseline to follow-up were compared between the intervention and control groups using analysis of variance and Chi-square tests. Intervention group participants were stratified by English proficiency and compared to assess baseline and follow-up responses by language. Results. After the intervention, participants in the intervention group had a significantly greater increase in knowledge about the poison center, were more likely to have the correct poison center phone number at home, and had greater behavioral intention to use the poison center compared to control group participants. At baseline, Spanish-primary-language participants with limited English proficiency had less knowledge about the poison center, were less likely to have the poison center number at home, and had lower behavioral intention to use the poison center than English proficient participants, but significantly improved after the intervention. Conclusions. This video module, when presented by a community organization's instructors, was highly effective in improving knowledge, behavior, and behavioral intention concerning use of poison centers within a low-income, language-diverse population.
C1 [Kelly, N. R.] Univ Texas SW Med Ctr Dallas, Dept Pediat, Dallas, TX 75390 USA.
[Harding, J. T.] DePelchin Childrens Ctr, Houston, TX USA.
[Fulton, J. E.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Kozinetz, C. A.] Baylor Coll Med, Dept Pediat, Houston, TX 77030 USA.
RP Kelly, NR (reprint author), Childrens Med Ctr, 1935 Med Dist Dr, Dallas, TX 75235 USA.
EM Nancy.Kelly@childrens.com
FU Charlotte and Jamil Azzam Foundation
FX This study was funded by the Charlotte and Jamil Azzam Foundation.
NR 20
TC 0
Z9 0
U1 0
U2 4
PU INFORMA HEALTHCARE
PI NEW YORK
PA 52 VANDERBILT AVE, NEW YORK, NY 10017 USA
SN 1556-3650
EI 1556-9519
J9 CLIN TOXICOL
JI Clin. Toxicol.
PD JAN
PY 2014
VL 52
IS 1
BP 54
EP 62
DI 10.3109/15563650.2013.863328
PG 9
WC Toxicology
SC Toxicology
GA 286XF
UT WOS:000329501900009
PM 24299276
ER
PT J
AU Krahn, GL
Reyes, M
Fox, M
AF Krahn, Gloria L.
Reyes, Michele
Fox, Michael
TI Toward a conceptual model for national policy and practice
considerations
SO DISABILITY AND HEALTH JOURNAL
LA English
DT Article
DE Chronic conditions; Chronic disease; Disability; National
ID PHYSICAL-DISABILITIES; HEALTH DISPARITIES; UNITED-STATES; ADULTS; LIFE
AB Chronic diseases and conditions are serious threats to the population's health. Chronic diseases represent seven of the top ten causes of mortality in the U. S. and are major economic drivers underlying burgeoning national health costs. People with disabilities experience dramatically higher rates of some chronic conditions, but only recently has this problem been recognized. We propose a set of contributing factors and a model to help better understand the relationship of disability with chronic disease. The paper summarizes current CDC initiatives to include disability status and considerations in public health surveys and programs, exemplifying a strategy to promote inclusion of people with disabilities in mainstream programs wherever possible; use cross-disability strategies for conditions unique to people with disabilities where necessary; and implement condition-specific approaches where essential. This initial model is intended to invite dialog on a conceptual framework for preventing chronic conditions and additional functional limitations among people with disabilities. Published by Elsevier Inc.
C1 [Krahn, Gloria L.; Reyes, Michele; Fox, Michael] Ctr Dis Control & Prevent, Div Human Dev & Disabil, Atlanta, GA USA.
RP Krahn, GL (reprint author), 1600 Clifton Rd NE,MS E88, Atlanta, GA 30333 USA.
EM gfk2@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 32
TC 11
Z9 11
U1 0
U2 3
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1936-6574
EI 1876-7583
J9 DISABIL HEALTH J
JI Disabil. Health J.
PD JAN
PY 2014
VL 7
IS 1
BP 13
EP 18
DI 10.1016/j.dhjo.2013.06.006
PG 6
WC Health Care Sciences & Services; Health Policy & Services; Public,
Environmental & Occupational Health; Rehabilitation
SC Health Care Sciences & Services; Public, Environmental & Occupational
Health; Rehabilitation
GA 286VT
UT WOS:000329498100004
PM 24411502
ER
PT J
AU Pinney, SM
Biro, FM
Windham, GC
Herrick, RL
Yaghjyan, L
Calafat, AM
Succop, P
Sucharew, H
Ball, KM
Kato, K
Kushi, LH
Bornschein, R
AF Pinney, Susan M.
Biro, Frank M.
Windham, Gayle C.
Herrick, Robert L.
Yaghjyan, Lusine
Calafat, Antonia M.
Succop, Paul
Sucharew, Heidi
Ball, Kathleen M.
Kato, Kayoko
Kushi, Lawrence H.
Bornschein, Robert
TI Serum biomarkers of polyfluoroalkyl compound exposure in young girls in
Greater Cincinnati and the San Francisco Bay Area, USA
SO ENVIRONMENTAL POLLUTION
LA English
DT Article
DE Polyfluoroalkyl compounds (PFCs); Human milk; Biomonitoring; Drinking
water contaminants; Children
ID PERFLUOROOCTANOIC ACID PFOA; PERFLUORINATED COMPOUNDS; NATIONAL-HEALTH;
DRINKING-WATER; PERFLUOROALKYL COMPOUNDS; NHANES 1999-2000; HUMAN-MILK;
CHEMICALS; POPULATION; SUBSTANCES
AB PFC serum concentrations were measured in 6-8 year-old girls in Greater Cincinnati (GC) (N = 353) and the San Francisco Bay Area (SFBA) (N = 351). PFOA median concentration was lower in the SFBA than GC (5.8 vs. 7.3 ng/mL). In GC, 48/51 girls living in one area had PFOA concentrations above the NHANES 95th percentile for children 12-19 years (8.4 ng/mL), median 22.0 ng/mL. The duration of being breast fed was associated with higher serum PFOA at both sites and with higher PFOS, PFHxS and Me-PFOSA-AcOH concentrations in GC. Correlations of the PFC analytes with each other suggest that a source upriver from GC may have contributed to exposures through drinking water, and water treatment with granular activated carbon filtration resulted in less exposure for SWO girls compared to those in NKY. PFOA has been characterized as a drinking water contaminant, and water treatment systems effective in removing PFCs will reduce body burdens. (C) 2013 Elsevier Ltd. All rights reserved.
C1 [Pinney, Susan M.; Herrick, Robert L.; Succop, Paul; Bornschein, Robert] Univ Cincinnati, Coll Med, Dept Environm Hlth, Cincinnati, OH 45267 USA.
[Biro, Frank M.] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati, OH 45229 USA.
[Biro, Frank M.; Sucharew, Heidi; Ball, Kathleen M.] Cincinnati Childrens Hosp, Med Ctr, Cincinnati, OH 45229 USA.
[Windham, Gayle C.] Calif Dept Publ Hlth, Div Environm & Occupat Dis Control, Richmond, CA 94804 USA.
[Yaghjyan, Lusine] Washington Univ, St Louis, MO 63110 USA.
[Calafat, Antonia M.; Kato, Kayoko] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Div Sci Lab, Atlanta, GA 30341 USA.
[Kushi, Lawrence H.] Kaiser Permanente, Div Res, Oakland, CA 94612 USA.
RP Pinney, SM (reprint author), Univ Cincinnati, Coll Med, Dept Environm Hlth, POB 670056, Cincinnati, OH 45267 USA.
EM susan.pinney@uc.edu; frank.biro@cchmc.org; gayle.windham@cdph.ca.gov;
herricrl@mail.uc.edu; yaghjyanl@wudosis.wustl.edu; aic7@cdc.gov;
paul.succop@uc.edu; heidi.sucharew@cchmc.org; Kathleen.ball@cchmc.org;
kayoko.kato@cdc.hhs.gov; larry.kushi@kp.org; Robert.bornschein@uc.edu
RI Sucharew, Heidi/M-4338-2015;
OI Kushi, Lawrence/0000-0001-9136-1175
FU National Institute of Environmental Health Sciences; National Cancer
Institute [U01 ES12770, U01 ES019453, U01 ES019457]; University of
California [U01ES012801, U01ES019435, U01ES019457]; University of
Cincinnati Center for Environmental Genetics [P30-ES06096]; Molecular
Epidemiology in Children's Environmental Health [T32ES010957]; NCRR
[CTSA-Ul1RR026314, UL1RR024131]
FX Support for this project provided by the National Institute of
Environmental Health Sciences and the National Cancer Institute to the
University of Cincinnati/Cincinnati Children's Hospital Medical Center,
(U01 ES12770, U01 ES019453, U01 ES019457), the University of California
(U01ES012801, U01ES019435 and U01ES019457), the University of Cincinnati
Center for Environmental Genetics (P30-ES06096), and Molecular
Epidemiology in Children's Environmental Health (T32ES010957),
CTSA-Ul1RR026314 and UL1RR024131 from NCRR. We are grateful to Amanda
Kolb, Anita Southwick, Cendi Dahl and Anoush Mirabedi for study
coordination, Dr. Patrick Ryan for geocoding assistance, Dr. Aimin Chen
for his insightful review, and to Charles Dodson, Dr. Zsuzsanna
Kuklenyik, Xavier Bryant, Amal Wanigatunga, Brian Basden, Tao Jia and
Dr. Jack Reidy for the PFC measures in serum, Justin Bates for data
management and Veronica Ratliff for editorial assistance and to the
Greater Cincinnati and San Francisco Bay area breast cancer advocates
for observations, input and support. Disclaimer: The findings and
conclusions in this report are those of the authors and do not
necessarily represent the views of the National Institutes of Health or
the Centers for Disease Control and Prevention.
NR 49
TC 14
Z9 15
U1 1
U2 36
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0269-7491
EI 1873-6424
J9 ENVIRON POLLUT
JI Environ. Pollut.
PD JAN
PY 2014
VL 184
SI SI
BP 327
EP 334
DI 10.1016/j.envpol.2013.09.008
PG 8
WC Environmental Sciences
SC Environmental Sciences & Ecology
GA 285TZ
UT WOS:000329419200040
PM 24095703
ER
PT B
AU Hess, JJ
Marinucci, G
Schramm, PJ
Manangan, A
Luber, G
AF Hess, Jeremy J.
Marinucci, Gino
Schramm, Paul J.
Manangan, Arie
Luber, George
BE Pinkerton, KE
Rom, WN
TI Management of Climate Change Adaptation at the United States Centers for
Disease Control and Prevention
SO GLOBAL CLIMATE CHANGE AND PUBLIC HEALTH
SE Respiratory Medicine Series
LA English
DT Article; Book Chapter
DE Climate change and the CDC; CDC policies on climate change adaptation;
Public health policy on climate change; Climate change adaptation and
public policy; Climate and Health Program
ID PUBLIC-HEALTH INTERVENTIONS; COMPARATIVE RISK-ASSESSMENT; HEAT-RELATED
MORTALITY; ADAPTIVE MANAGEMENT; POLICY
AB As the nation's public health agency, CDC recognizes that climate change poses a multifaceted and potentially significant threat to domestic public health. To facilitate climate change preparedness in public health, the agency developed the Climate and Health Program, which is housed in the National Center for Environmental Health. The Program's mission is to translate science for public health partners, develop decision support tools to facilitate climate change adaptation in public health, and to serve as a credible leader in planning for the human health impacts of a changing climate. Since its formation, the Program has worked to articulate a public health approach to climate change and integrate science from public health and other sectors to facilitate public health adaptation efforts. The Program has developed an adaptive management framework for public health, the BRACE framework, and is working cooperatively with several state and local health departments to pursue an evidence-based approach to climate change adaptation. As public health's expertise and experience grows, the Climate and Health Program will work to continue disseminating relevant information for the increasing number of public health practitioners focused on reducing the adverse health effects of climate change.
C1 [Hess, Jeremy J.] Emory Sch Med & Publ Hlth, Atlanta, GA USA.
[Hess, Jeremy J.] CDC, Climate & Hlth Program, NCEH, Atlanta, GA 30333 USA.
[Marinucci, Gino; Schramm, Paul J.; Manangan, Arie; Luber, George] Ctr Dis Control & Prevent, Climate & Hlth Program, Div Environm Hazards & Hlth Effects, Natl Ctr Environm Hlth, Atlanta, GA USA.
RP Hess, JJ (reprint author), Emory Sch Med & Publ Hlth, Atlanta, GA USA.
EM jhess@emory.edu
NR 33
TC 3
Z9 3
U1 1
U2 2
PU HUMANA PRESS INC
PI TOTOWA
PA 999 RIVERVIEW DR, STE 208, TOTOWA, NJ 07512-1165 USA
BN 978-1-4614-8417-2; 978-1-4614-8416-5
J9 RESPIR MED SER
PY 2014
VL 7
BP 341
EP 360
DI 10.1007/978-1-4614-8417-2_20
D2 10.1007/978-1-4614-8417-2
PG 20
WC Environmental Sciences; Public, Environmental & Occupational Health;
Respiratory System
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health; Respiratory System
GA BJJ05
UT WOS:000328380700021
ER
PT J
AU Liu, Y
Croft, JB
Anderson, LA
Wheaton, AG
Presley-Cantrell, LR
Ford, ES
AF Liu, Yong
Croft, Janet B.
Anderson, Lynda A.
Wheaton, Anne G.
Presley-Cantrell, Letitia R.
Ford, Earl S.
TI The association of chronic obstructive pulmonary disease, disability,
engagement in social activities, and mortality among US adults aged 70
years or older, 1994-2006
SO INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
LA English
DT Article
DE chronic obstructive pulmonary disease; mortality; activities of daily
living; instrumental activities of daily living; disability
ID AIR-FLOW OBSTRUCTION; ELDERLY-PEOPLE; UNITED-STATES; PHYSICAL-ACTIVITY;
COMMUNITY; HEALTH; COPD; SUPPORT; ADL; LONELINESS
AB Purpose: To assess associations among chronic obstructive pulmonary disease (COPD), disability as measured by activities of daily living (ADL) and instrumental ADL (IADL), engagement in social activities, and death among elderly noninstitutionalized US residents.
Materials and methods: A nationally representative sample of 9,415 adults who were aged >70 years and responded to the Second Supplement on Aging survey in 1994-1996 and mortality follow-up study through 2006 were assessed. Multiple logistic regression analyses were performed to assess the risk of all-cause mortality in participants with COPD after accounting for age, sex, race/ethnicity, and smoking status.
Results: At baseline, approximately 9.6% of study participants reported having COPD. Compared with participants without COPD, those with COPD were significantly more likely (P<0.05) to have difficulty with at least one ADL (44.3% versus [vs] 27.5%) and with at least one IADL (59.9% vs 40.2%), significantly less likely to be engaged in social activities (32.6% vs 26.3%), and significantly more likely to die by 2006 (70.7% vs 60.4%; adjusted risk ratio 1.15, P<0.05). The association between COPD and risk for death was moderately attenuated by disability status.
Conclusion: COPD is positively associated with disability and mortality risk among US adults aged >= 70 years. The significant relationship between COPD and mortality risk was moderately attenuated, but was not completely explained by stages of ADL and IADL limitations and social activities.
C1 [Liu, Yong; Croft, Janet B.; Wheaton, Anne G.; Ford, Earl S.] Emory Univ, Epidemiol & Surveillance Branch, Atlanta, GA 30322 USA.
[Anderson, Lynda A.] Emory Univ, Hlth Aging Program, Div Populat Hlth, CDC, Atlanta, GA 30322 USA.
[Anderson, Lynda A.] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA.
[Presley-Cantrell, Letitia R.] Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, Program Dev & Serv Management, Atlanta, GA USA.
RP Liu, Y (reprint author), Ctr Dis Control & Prevent, Div Populat Hlth, Epidemiol & Surveillance Branch, 4770 Buford Highway Northeast,Mailstop F-78, Atlanta, GA 30341 USA.
EM ikd8@cdc.gov
NR 46
TC 11
Z9 11
U1 3
U2 10
PU DOVE MEDICAL PRESS LTD
PI ALBANY
PA PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND
SN 1176-9106
EI 1178-2005
J9 INT J CHRONIC OBSTR
JI Int. J. Chronic Obstr. Pulm. Dis.
PY 2014
VL 9
BP 75
EP 83
DI 10.2147/COPD.S53676
PG 9
WC Respiratory System
SC Respiratory System
GA 290ZX
UT WOS:000329798400001
PM 24477269
ER
PT J
AU Holman, DM
Benard, V
Roland, KB
Watson, M
Liddon, N
Stokley, S
AF Holman, Dawn M.
Benard, Vicki
Roland, Katherine B.
Watson, Meg
Liddon, Nicole
Stokley, Shannon
TI Barriers to Human Papillomavirus Vaccination Among US Adolescents A
Systematic Review of the Literature
SO JAMA PEDIATRICS
LA English
DT Review
ID NUTRITION EXAMINATION SURVEY; IMMUNIZATION SURVEY-TEEN;
STATES-NATIONAL-HEALTH; ETHNIC-MINORITY GIRLS; AGED 13-17 YEARS; HPV
VACCINE; UNITED-STATES; AFRICAN-AMERICAN; CERVICAL-CANCER; PUBLIC-HEALTH
AB IMPORTANCE Since licensure of the human papillomavirus (HPV) vaccine in 2006, HPV vaccine coverage among US adolescents has increased but remains low compared with other recommended vaccines.
OBJECTIVE To systematically review the literature on barriers to HPV vaccination among US adolescents to inform future efforts to increase HPV vaccine coverage.
EVIDENCE REVIEW We searched PubMed and previous review articles to identify original research articles describing barriers to HPV vaccine initiation and completion among US adolescents. Only articles reporting data collected in 2009 or later were included. Findings from 55 relevant articles were summarized by target populations: health care professionals, parents, underserved and disadvantaged populations, and males.
FINDINGS Health care professionals cited financial concerns and parental attitudes and concerns as barriers to providing the HPV vaccine to patients. Parents often reported needing more information before vaccinating their children. Concerns about the vaccine's effect on sexual behavior, low perceived risk of HPV infection, social influences, irregular preventive care, and vaccine cost were also identified as potential barriers among parents. Some parents of sons reported not vaccinating their sons because of the perceived lack of direct benefit. Parents consistently cited health care professional recommendations as one of the most important factors in their decision to vaccinate their children.
CONCLUSIONS AND RELEVANCE Continued efforts are needed to ensure that health care professionals and parents understand the importance of vaccinating adolescents before they become sexually active. Health care professionals may benefit from guidance on communicating HPV recommendations to patients and parents. Further efforts are also needed to reduce missed opportunities for HPV vaccination when adolescents interface with the health care system. Efforts to increase uptake should take into account the specific needs of subgroups within the population. Efforts that address system-level barriers to vaccination may help to increase overall HPV vaccine uptake.
C1 [Holman, Dawn M.; Benard, Vicki; Roland, Katherine B.; Watson, Meg] Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Div Canc Prevent & Control, Atlanta, GA 30341 USA.
[Liddon, Nicole] Ctr Dis Control & Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Div Sexually Transmitted Dis Prevent, Atlanta, GA 30341 USA.
[Stokley, Shannon] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30341 USA.
RP Holman, DM (reprint author), Ctr Dis Control & Prevent, Div Canc Prevent & Control, 4770 Buford Hwy NE,Mailstop F-76, Atlanta, GA 30341 USA.
EM dholman@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 84
TC 155
Z9 156
U1 8
U2 46
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA
SN 2168-6203
EI 2168-6211
J9 JAMA PEDIATR
JI JAMA Pediatr.
PD JAN
PY 2014
VL 168
IS 1
BP 76
EP 82
DI 10.1001/jamapediatrics.2013.2752
PG 7
WC Pediatrics
SC Pediatrics
GA 291RK
UT WOS:000329846600016
PM 24276343
ER
PT J
AU Moreno, MA
AF Moreno, Megan A.
TI Phthalate Exposure and Health Risks
SO JAMA PEDIATRICS
LA English
DT Editorial Material
C1 Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
RP Moreno, MA (reprint author), Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
NR 0
TC 0
Z9 1
U1 0
U2 3
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 515 N STATE ST, CHICAGO, IL 60654-0946 USA
SN 2168-6203
EI 2168-6211
J9 JAMA PEDIATR
JI JAMA Pediatr.
PD JAN
PY 2014
VL 168
IS 1
BP 96
EP 96
PG 1
WC Pediatrics
SC Pediatrics
GA 291RK
UT WOS:000329846600019
PM 24394978
ER
PT J
AU Zhou, XL
Kramer, JP
Calafat, AM
Ye, XY
AF Zhou, Xiaoliu
Kramer, Joshua P.
Calafat, Antonia M.
Ye, Xiaoyun
TI Automated on-line column-switching high performance liquid
chromatography isotope dilution tandem mass spectrometry method for the
quantification of bisphenol A, bisphenol F, bisphenol S, and 11 other
phenols in urine
SO JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL
AND LIFE SCIENCES
LA English
DT Article
DE Bisphenol A; Bisphenol F; Bisphenol S; Exposure; HPLC-MS/MS; Urine
ID EXTRACTION
AB Human exposure to bisphenol A (BPA) is widespread. However, in recent years, bisphenol analogs such as bisphenol S (BPS) and bisphenol F (BPF) are replacing BPA in the production of some consumer products. Because human exposure to these alternative bisphenols may occur, biomonitoring of these bisphenol analogs is warranted. In the present study, we developed and validated a sensitive and selective method that uses on-line solid phase extraction coupled to high performance liquid chromatography-isotope dilution tandem mass spectrometry with peak focusing to measure BPA, BPF, BPS, and 11 other environmental phenols in urine. The method required a small amount of sample (100 ILL) and minimal sample pretreatment. The limits of detection were 0.03 ng/mL (BPS), 0.06 ng/mL (BPF), 0.10 ng/mL (BPA), and ranged from 0.1 ng/mL to 1.0 ng/mL for the other 11 phenols. In 100 urine samples collected in 2009-2012 from a convenience group of anonymous adults in the United States, of the three bisphenols, we detected BPA at the highest frequency and median concentrations (95%, 0.72 ng/mL), followed by BPS (78%, 0.13 ng/mL) and BPF (55%, 0.08 ng/mL). This sensitive, rugged, and labor and cost-effective method could be used for the analysis of large number of samples for epidemiologic studies. Published by Elsevier B.V.
C1 [Zhou, Xiaoliu; Kramer, Joshua P.; Calafat, Antonia M.; Ye, Xiaoyun] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Div Sci Lab, Atlanta, GA 30341 USA.
RP Ye, XY (reprint author), Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Div Sci Lab, 4770 Buford Hwy,Mailstop F53, Atlanta, GA 30341 USA.
EM xay5@cdc.gov
FU U.S. Department of Energy; CDC
FX This work was supported in part by an appointment (Joshua P. Kramer) to
the Research Participation Program at the Centers for Disease Control
and Prevention (CDC), administered by the Oak Ridge Institute for
Science and Education through an interagency agreement between the U.S.
Department of Energy and CDC.
NR 21
TC 47
Z9 48
U1 7
U2 111
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1570-0232
EI 1873-376X
J9 J CHROMATOGR B
JI J. Chromatogr. B
PD JAN 1
PY 2014
VL 944
BP 152
EP 156
DI 10.1016/j.jchromb.2013.11.009
PG 5
WC Biochemical Research Methods; Chemistry, Analytical
SC Biochemistry & Molecular Biology; Chemistry
GA 290PH
UT WOS:000329770300025
PM 24316527
ER
PT J
AU Kaddumukasa, MA
Mutebi, JP
Lutwama, JJ
Masembe, C
Akol, AM
AF Kaddumukasa, M. A.
Mutebi, J. -P.
Lutwama, J. J.
Masembe, C.
Akol, A. M.
TI Mosquitoes of Zika Forest, Uganda: Species Composition and Relative
Abundance
SO JOURNAL OF MEDICAL ENTOMOLOGY
LA English
DT Article
DE Zika forest; Uganda; mosquito species composition; arbovirus vector
ID ONYONG-NYONG FEVER; SOUTH-CENTRAL UGANDA; YELLOW-FEVER; EPIDEMIC; VIRUS;
EMERGENCE; DIPTERA; MONKEYS; ABSENCE
AB Mosquito collections were conducted in Zika Forest near Entebbe, Uganda, from July 2009 through June 2010 using CO2-baited light traps, ovitraps, and human-baited catches. In total, 163,790 adult mosquitoes belonging to 12 genera and 58 species were captured. Of these, 22 species (38%) were captured in Zika Forest for the first time. All the new records found in the forest in this study had previously been captured in other regions of Uganda, implying that they are native to the country and do not represent new introductions. More than 20 species previously collected in Zika Forest were not detected in our collections, and this may suggest a change in the mosquito fauna during the past 40 yr or variation in species composition from year to year. Arboviruses of public health importance have previously been isolated from >50% of the 58 mosquito species captured in Zika Forest, which suggests a high potential for transmission and maintenance of a wide range of arboviruses in Zika Forest.
C1 [Kaddumukasa, M. A.; Masembe, C.; Akol, A. M.] Makerere Univ, Dept Biol Sci, Coll Nat Sci, Kampala, Uganda.
[Kaddumukasa, M. A.; Lutwama, J. J.] Uganda Virus Res Inst, Dept Arbovirol, Entebbe, Uganda.
[Mutebi, J. -P.] Ctr Dis Control & Prevent, Div Vector Borne Infect Dis, Ft Collins, CO 80521 USA.
RP Akol, AM (reprint author), Makerere Univ, Dept Biol Sci, Coll Nat Sci, POB 7062, Kampala, Uganda.
EM aakol@sci.mak.ac.ug
FU Uganda Virus Research Institute; Department of Biological Sciences,
Makerere University; UVRIE; CDC; Organization for Women in Science for
the Developing World (OWSDW)
FX We thank F. Ssenfuka, T. Muwawu, J.-F. Lwanga, J. Mugga, and S. Wakaalo
for their assistance in the field and in the laboratory. We thank R.
Kading and M. Crabtree of the Centers for Disease Control and Prevention
(CDC) and the entomology team at Kenya Medical Research Institute
(KEMRI), Nairobi, for their assistance with mosquito identification. We
thank the Uganda Virus Research Institute and the Department of
Biological Sciences, Makerere University, for financial assistance. This
research was partly funded by in part by UVRIE, the CDC and by a grant
from the Organization for Women in Science for the Developing World
(OWSDW) formerly TWOWS to M. Kaddumukasa.
NR 45
TC 5
Z9 6
U1 1
U2 24
PU ENTOMOLOGICAL SOC AMER
PI LANHAM
PA 10001 DEREKWOOD LANE, STE 100, LANHAM, MD 20706-4876 USA
SN 0022-2585
EI 1938-2928
J9 J MED ENTOMOL
JI J. Med. Entomol.
PD JAN
PY 2014
VL 51
IS 1
BP 104
EP 113
DI 10.1603/ME12269
PG 10
WC Entomology; Veterinary Sciences
SC Entomology; Veterinary Sciences
GA 291CF
UT WOS:000329804600012
PM 24605459
ER
PT J
AU Barrera, R
Amador, M
Acevedo, V
Caban, B
Felix, G
Mackay, AJ
AF Barrera, Roberto
Amador, Manuel
Acevedo, Veronica
Caban, Belkis
Felix, Gilberto
Mackay, Andrew J.
TI Use of the CDC Autocidal Gravid Ovitrap to Control and Prevent Outbreaks
of Aedes aegypti (Diptera: Culicidae)
SO JOURNAL OF MEDICAL ENTOMOLOGY
LA English
DT Article
DE Aedes aegypti; vector control; mosquito trap; dengue; outbreak
ID LETHAL OVITRAP; DENGUE VECTORS; BG-SENTINEL; FIELD PERFORMANCE; NORTH
QUEENSLAND; STICKY OVITRAPS; MALE MOSQUITOS; POPULATION; AUSTRALIA;
ADULT
AB Populations of Aedes aegypti (L.) can be managed through reductions in adult mosquito survival, number of offspring produced, or both. Direct adult mortality can be caused by the use of space sprays or residual insecticides to mosquito resting sites, and with a variety of residual insecticide-impregnated surfaces that are being tested, such as curtains, covers for water-storage vessels, bednets, and ovitraps. The fertility of Ae. aegypti populations can be reduced by the use of autocidal oviposition cups that prevent the development of mosquitoes inside the trap by mechanical means or larvicides, as well as by releasing sterile, transgenic, and para-transgenic mosquitoes. Survival and fertility can be simultaneously reduced by capturing gravid female Ae. aegypti with sticky gravid traps. We tested the effectiveness of the novel Centers for Disease Control and Prevention autocidal gravid ovitrap (CDC-AGO trap) to control natural populations of Ae. aegypti under field conditions in two isolated urban areas (reference vs. intervention areas) in southern Puerto Rico for 1 yr. There were significant reductions in the captures of female Ae. aegypti ( 53D70%) in the intervention area. The presence of three to four AGO control traps per home in 81% of the houses prevented outbreaks of Ae. aegypti, which would be expected after rains. Mosquito captures in BG-Sentinel and AGO traps were significantly and positively correlated, showing that AGO traps are useful and inexpensive mosquito surveillance devices. The use of AGO traps to manage Ae. aegypti populations is compatible with other control means such as source reduction, larviciding, adulticiding, sterile insect techniques, induced cytoplasmic incompatibility, and dominant lethal gene systems.
C1 [Barrera, Roberto; Amador, Manuel; Acevedo, Veronica; Caban, Belkis; Felix, Gilberto; Mackay, Andrew J.] Ctr Dis Control & Prevent, Entomol & Ecol Act, Dengue Branch, San Juan, PR 00920 USA.
RP Barrera, R (reprint author), Ctr Dis Control & Prevent, Entomol & Ecol Act, Dengue Branch, 1324 Calle Canada, San Juan, PR 00920 USA.
EM rbarrera@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 37
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U1 4
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PU ENTOMOLOGICAL SOC AMER
PI LANHAM
PA 10001 DEREKWOOD LANE, STE 100, LANHAM, MD 20706-4876 USA
SN 0022-2585
EI 1938-2928
J9 J MED ENTOMOL
JI J. Med. Entomol.
PD JAN
PY 2014
VL 51
IS 1
BP 145
EP 154
DI 10.1603/ME13096
PG 10
WC Entomology; Veterinary Sciences
SC Entomology; Veterinary Sciences
GA 291CF
UT WOS:000329804600017
PM 24605464
ER
PT J
AU Lutomiah, J
Musila, L
Makio, A
Ochieng, C
Koka, H
Chepkorir, E
Mutisya, J
Mulwa, F
Khamadi, S
Miller, BR
Bast, J
Schnabel, D
Wurapa, EK
Sang, R
AF Lutomiah, Joel
Musila, Lillian
Makio, Albina
Ochieng, Caroline
Koka, Hellen
Chepkorir, Edith
Mutisya, James
Mulwa, Francis
Khamadi, Samoel
Miller, Barry R.
Bast, Joshua
Schnabel, David
Wurapa, Eyako K.
Sang, Rosemary
TI Ticks and Tick-Borne Viruses From Livestock Hosts in Arid and Semiarid
Regions of the Eastern and Northeastern Parts of Kenya
SO JOURNAL OF MEDICAL ENTOMOLOGY
LA English
DT Article
DE Kenya; tick; arbovirus; surveillance; semiarid
ID CONGO HEMORRHAGIC-FEVER; NAIROBI SHEEP DISEASE; IXODID TICKS; DHORI
VIRUS; FAMILY BUNYAVIRIDAE; GENUS NAIROVIRUS; IJARA DISTRICT; RT-PCR;
AFRICA; DUGBE
AB Biodiversity and relative abundance of ticks and associated arboviruses in Garissa (northeastern) and Isiolo (eastern) provinces of Kenya were evaluated. Ticks were collected from livestock, identified to species, pooled, and processed for virus isolation. In Garissa, Rhipicephalus pulchellus Gerstacker (57.8%) and Hyalomma truncatum Koch (27.8%) were the most abundant species sampled, whereas R. pulchellus (80.4%) and Amblyomma gemma Donitz (9.6%) were the most abundant in Isiolo. Forty-four virus isolates, comprising Dugbe virus (DUGV; n = 22) and Kupe virus (n = 10; Bunyaviridae: Nirovirus), Dhori virus (DHOV; n = 10; Orthomyxoviridae: Thogotovirus), and Ngari virus (NRIV; n = 2; Bunyaviridae: Orthobunyavirus), were recovered mostly from R. pulchellus sampled in Isiolo. DUGV was mostly recovered from R. pulchellus from sheep and cattle, and DHOV from R. pulchellus from sheep. All Kupe virus isolates were from Isiolo ticks, including R. pulchellus from all the livestock, A. gemma and Amblyomma variegatum F. from cattle, and H. truncatum from goat. NRIV was obtained from R. pulchellus and A. gemma sampled from cattle in Isiolo and Garissa, respectively, while all DHOV and most DUGV (n = 12) were from R. pulchellus sampled from cattle in Garissa. DUGV was also recovered from H. truncatum and Amblyomma hebraeum Koch from cattle and from Rhipicephalus annulatus Say from camel. This surveillance study has demonstrated the circulation of select tick-borne viruses in parts of eastern and northeastern provinces of Kenya, some of which are of public health importance. The isolation of NRIV from ticks is particularly significant because it is usually known to be a mosquito-borne virus affecting humans.
C1 [Lutomiah, Joel; Sang, Rosemary] Kenya Govt Med Res Ctr, Ctr Virus Res, Nairobi 00100, Kenya.
[Lutomiah, Joel; Musila, Lillian; Makio, Albina; Ochieng, Caroline; Koka, Hellen; Mutisya, James; Khamadi, Samoel; Wurapa, Eyako K.; Sang, Rosemary] US Army Med Res Unit, Div Emerging Infect Dis, Nairobi 00621, Kenya.
[Chepkorir, Edith; Mulwa, Francis] Int Ctr Insect Physiol & Ecol, Nairobi 00100, Kenya.
[Miller, Barry R.] Ctr Dis Control & Prevent, US Dept HHS, Div Vector Borne Infect Dis, Ft Collins, CO 80521 USA.
[Bast, Joshua] US Army Med Res Unit, Dept Entomol, Kisumu 40100, Kenya.
[Schnabel, David] Walter Reed Army Inst Res, Silver Spring, MD 20910 USA.
RP Lutomiah, J (reprint author), Kenya Govt Med Res Ctr, Ctr Virus Res, POB 54628, Nairobi 00100, Kenya.
EM joel.lutomiah@usamru-k.org
FU Department of Emerging Infectious Diseases (DEID); USAMRU-K; AFHSC;
Global Disease Detection (GDD), CDC
FX We thank Dunstone Beti, John Gachoya, Reuben Lugalia, and Anthony Mutai
for their expert contribution in tick sampling and identification. We
also acknowledge Santos Yalwala for drawing the site map. This project
was supported by the Department of Emerging Infectious Diseases (DEID),
USAMRU-K, AFHSC, and the Global Disease Detection (GDD), CDC. The
content is solely the views of the authors and does not represent the
official views of AFHSC or GDD.
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U1 2
U2 7
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0022-2585
EI 1938-2928
J9 J MED ENTOMOL
JI J. Med. Entomol.
PD JAN
PY 2014
VL 51
IS 1
BP 269
EP 277
DI 10.1603/ME13039
PG 9
WC Entomology; Veterinary Sciences
SC Entomology; Veterinary Sciences
GA 291CF
UT WOS:000329804600031
PM 24605478
ER
PT J
AU Calfee, MW
Rose, LJ
Tufts, J
Morse, S
Clayton, M
Touati, A
Griffin-Gatchalian, N
Slone, C
McSweeney, N
AF Calfee, M. Worth
Rose, Laura J.
Tufts, Jenia
Morse, Stephen
Clayton, Matt
Touati, Abderrahmane
Griffin-Gatchalian, Nicole
Slone, Christina
McSweeney, Neal
TI Evaluation of sampling methods for Bacillus spore-contaminated HVAC
filters
SO JOURNAL OF MICROBIOLOGICAL METHODS
LA English
DT Article
DE HVAC sampling; Anthrax; Bacillus anthracis; biological agent; bioterror
ID NONPOROUS SURFACES; VENTILATION DUCTS; FLUIDIZED SPORES; COLLECTION;
DEPOSITION; RELEASE; DECONTAMINATION; BIOTERRORISM; INFILTRATION;
BUILDINGS
AB The objective of this study was to compare an extraction-based sampling method to two vacuum-based sampling methods (vacuum sock and 37 mm cassette filter) with regards to their ability to recover Bacillus atrophaeus spores (surrogate for Bacillus anthracis) from pleated heating, ventilation, and air conditioning (HVAC) filters that are typically found in commercial and residential buildings. Electrostatic and mechanical HVAC filters were tested, both without and after loading with dust to 50% of their total holding capacity. The results were analyzed by one-way ANOVA across material types, presence or absence of dust, and sampling device. The extraction method gave higher relative recoveries than the two vacuum methods evaluated (p <= 0.001). On average, recoveries obtained by the vacuum methods were about 30% of those achieved by the extraction method. Relative recoveries between the two vacuum methods were not significantly different (p > 0.05). Although extraction methods yielded higher recoveries than vacuum methods, either HVAC filter sampling approach may provide a rapid and inexpensive mechanism for understanding the extent of contamination following a wide-area biological release incident. Published by Elsevier B.V.
C1 [Calfee, M. Worth; Tufts, Jenia] US EPA, Natl Homeland Secur Res Ctr, Res Triangle Pk, NC 27711 USA.
[Rose, Laura J.; Morse, Stephen] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Tufts, Jenia] Oak Ridge Inst Sci & Educ, Res Triangle Pk, NC USA.
[Clayton, Matt; Touati, Abderrahmane; Griffin-Gatchalian, Nicole; McSweeney, Neal] ARCADIS Geraghty & Miller Inc, Durham, NC USA.
[Slone, Christina] Kultech Inc, Cary, NC USA.
RP Calfee, MW (reprint author), US EPA, MD E343-06,109 TW Alexander Dr, Res Triangle Pk, NC 27711 USA.
EM calfee.worth@epa.gov
FU U.S. Environmental Protection Agency, through its Office of Research and
Development [EP-C-09-027]; CDC [RW-75-92345701]; U.S. EPA
[RW-75-92345701]; ARCADIS, Inc.
FX The U.S. Environmental Protection Agency, through its Office of Research
and Development, directed the research described herein under
EP-C-09-027 with ARCADIS, Inc. This study was funded through an
interagency agreement between the CDC and the U.S. EPA (RW-75-92345701).
This manuscript has been subject to an administrative review but the
findings and conclusions in this article are of the authors, and do not
necessarily reflect the views of the EPA or CDC. No official endorsement
should be inferred. The U.S. EPA and CDC do not endorse the purchase or
sale of any commercial products or services.
NR 27
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U1 0
U2 14
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0167-7012
EI 1872-8359
J9 J MICROBIOL METH
JI J. Microbiol. Methods
PD JAN
PY 2014
VL 96
BP 1
EP 5
DI 10.1016/j.mimet.2013.10.012
PG 5
WC Biochemical Research Methods; Microbiology
SC Biochemistry & Molecular Biology; Microbiology
GA 290PO
UT WOS:000329771000001
PM 24184312
ER
PT J
AU Gilbert, SE
Rose, LJ
Howard, M
Bradley, MD
Shah, S
Silvestri, E
Schaefer, FW
Noble-Wang, J
AF Gilbert, Sarah E.
Rose, Laura J.
Howard, Michele
Bradley, Meranda D.
Shah, Sanjiv
Silvestri, Erin
Schaefer, Frank W., III
Noble-Wang, Judith
TI Evaluation of swabs and transport media for the recovery of Yersinia
pestis
SO JOURNAL OF MICROBIOLOGICAL METHODS
LA English
DT Article
DE Yersinia pestis; Transport media; Swab; Recovery
ID BACILLUS-ANTHRACIS SPORES; PROCESSING METHOD; SURFACE; PERSISTENCE;
SURVIVAL; WATER
AB The Government Accountability Office report investigating the surface sampling methods used during the 2001 mail contamination with Bacillus anthracis brought to light certain knowledge gaps that existed regarding environmental sampling with biothreat agents. Should a contamination event occur that involves non-spore forming biological select agents, such as Yersinia pestis, surface sample collection and processing protocols specific for these organisms will be needed. Two Y. pestis strains (virulent and avirulent), four swab types (polyester, macrofoam, rayon, and cotton), two pre-moistening solutions, six transport media, three temperatures, two levels of organic load, and four processing methods (vortexing, sonicating, combined sonicating and vortexing, no agitation) were evaluated to determine the conditions that would yield the highest percent of cultivable Y. pestis cells after storage. The optimum pre-moistening agent/transport media combination varied with the Y. pestis strain and swab type. Directly inoculated macrofoam swabs released the highest percent of cells into solution (93.9% recovered by culture) and rayon swabs were considered the second best swab option (77.0% recovered by culture). Storage at 4 degrees C was found to be optimum for all storage times and transport media. In a worst case scenario, where the Y. pestis strain is not known and sample processing and analyses could not occur until 72 h after sampling, macrofoam swabs pre-moistened with PBS supplemented with 0.05% Triton X-100 (PBSTX), stored at 4 degrees C in neutralizing buffer (NB) as a transport medium (PBSTX/NB) or pre-moistened with NB and stored in PBSTX as a transport medium (NB/PBSTX), then vortexed 3 min in the transport medium, performed significantly better than all other conditions for macrofoam swabs, regardless of strain tested (mean 12 72 h recovery of 85.9-105.1%, p < 0.001). In the same scenario, two combinations of pre-moistening medium/transport medium were found to be optimal for rayon swabs stored at 4 degrees C (p < 0.001), then sonicated 3 min in the transport medium; PBSTX/PBSTX and NB/PBSTX (mean 12-72 h recovery of 83.7-110.1%). Published by Elsevier B.V.
C1 [Gilbert, Sarah E.] North Adams Reg Hosp, North Adams, MA USA.
[Rose, Laura J.; Howard, Michele; Bradley, Meranda D.; Noble-Wang, Judith] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA USA.
[Shah, Sanjiv; Silvestri, Erin; Schaefer, Frank W., III] US EPA, Off Res & Dev, Natl Homeland Secur Res Ctr, Cincinnati, OH 45268 USA.
RP Rose, LJ (reprint author), 1600 Clifton Rd NE,MS-C16, Atlanta, GA 30329 USA.
EM lrose@cdc.gov
NR 20
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U1 0
U2 7
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0167-7012
EI 1872-8359
J9 J MICROBIOL METH
JI J. Microbiol. Methods
PD JAN
PY 2014
VL 96
BP 35
EP 41
DI 10.1016/j.mimet.2013.10.017
PG 7
WC Biochemical Research Methods; Microbiology
SC Biochemistry & Molecular Biology; Microbiology
GA 290PO
UT WOS:000329771000007
PM 24184311
ER
PT J
AU Schilling, KA
Cartwright, EJ
Stamper, J
Locke, M
Esposito, DH
Balaban, V
Mintz, E
AF Schilling, Katharine A.
Cartwright, Emily J.
Stamper, John
Locke, Michael
Esposito, Douglas H.
Balaban, Victor
Mintz, Eric
TI Diarrheal Illness Among US Residents Providing Medical Services in Haiti
During the Cholera Epidemic, 2010 to 2011
SO JOURNAL OF TRAVEL MEDICINE
LA English
DT Article
ID TRAVELERS
AB Although nosocomial transmission of cholera is rare, two US healthcare workers (HCW) became ill with cholera after providing medical services during the Haiti cholera epidemic. To assess the incidence of diarrheal illness and explore preventive health behaviors practiced by US residents who provided medical services in Haiti, we conducted a cross-sectional, anonymous, web-based survey. We e-mailed 896 participants from 50 US-based, health-focused non-governmental organizations (NGOs), of whom 381 (43%) completed the survey. Fifty-six percent of respondents (n=215) reported providing some care for patients with cholera. Diarrhea was reported by 31 (8%) respondents. One person was diagnosed with cholera by serologic testing. NGOs responding to international emergencies should ensure ample access to basic hygiene supplies and should promote their use to reduce the incidence of diarrheal illness among HCW working overseas.
C1 [Schilling, Katharine A.; Cartwright, Emily J.; Mintz, Eric] US Ctr Dis Control & Prevent, Div Foodborne Waterborne & Environm Dis, Waterborne Dis Prevent Branch, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30307 USA.
[Cartwright, Emily J.] CDC, Epidem Intelligence Serv, Sci Educ & Profess Dev Program Off, OSELS, Atlanta, GA 30333 USA.
[Cartwright, Emily J.] Emory Univ, Sch Med, Div Infect Dis, Atlanta, GA USA.
[Stamper, John] US Ctr Dis Control & Prevent, Off Director, Off Informat, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30307 USA.
[Locke, Michael] US Ctr Dis Control & Prevention Via Sci Applicat, Div Foodborne Waterborne & Environm Dis, Waterborne Dis Prevent Branch, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30307 USA.
[Esposito, Douglas H.; Balaban, Victor] US Ctr Dis Control & Prevent, Div Global Migrat & Quarantine, Travelers Hlth Branch, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30307 USA.
RP Schilling, KA (reprint author), US Ctr Dis Control & Prevent, Div Foodborne Waterborne & Environm Dis, Waterborne Dis Prevent Branch, Natl Ctr Emerging & Zoonot Infect Dis, 1600 Clifton Rd,Mailstop C09, Atlanta, GA 30307 USA.
EM kschilling@cdc.gov
NR 11
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U1 0
U2 3
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1195-1982
EI 1708-8305
J9 J TRAVEL MED
JI J. Travel Med.
PD JAN
PY 2014
VL 21
IS 1
BP 55
EP 57
DI 10.1111/jtm.12075
PG 3
WC Medicine, General & Internal
SC General & Internal Medicine
GA 285DC
UT WOS:000329372400011
PM 24383654
ER
PT J
AU Jentes, ES
Blanton, JD
Johnson, KJ
Petersen, BW
Lamias, MJ
Robertson, K
Franka, R
Muhm, D
Rupprecht, CE
Marano, N
Brunette, GW
AF Jentes, Emily S.
Blanton, Jesse D.
Johnson, Katherine J.
Petersen, Brett W.
Lamias, Mark J.
Robertson, Kis
Franka, Richard
Muhm, Daniel
Rupprecht, Charles E.
Marano, Nina
Brunette, Gary W.
TI The Global Availability of Rabies Immune Globulin and Rabies Vaccine in
Clinics Providing Indirect Care to Travelers
SO JOURNAL OF TRAVEL MEDICINE
LA English
DT Article
AB We assessed rabies vaccine (RV) and immune globulin (RIG) availability on the local market by querying US Embassy medical staff worldwide. Of 112 responses, 23% were from West, Central, and East Africa. RV and RIG availability varied by region. Possible rabies exposures accounted for 2% of all travelers' health inquiries.
C1 [Jentes, Emily S.; Johnson, Katherine J.; Marano, Nina; Brunette, Gary W.] Ctr Dis Control & Prevent CDC, Div Global Migrat & Quarantine, NCEZID, Atlanta, GA 30333 USA.
[Blanton, Jesse D.; Petersen, Brett W.; Robertson, Kis; Franka, Richard] CDC, Div High Consequence Pathogens & Pathol, NCEZID, Atlanta, GA 30333 USA.
[Lamias, Mark J.] CDC, Off Informat, NCEZID, Atlanta, GA 30333 USA.
[Lamias, Mark J.] Sci Applicat Int Corp, Atlanta, GA USA.
[Muhm, Daniel] US Dept State, Off Med Serv, Washington, DC 20520 USA.
[Rupprecht, Charles E.] Global Alliance Rabies Control, Manhattan, KS USA.
RP Jentes, ES (reprint author), Ctr Dis Control & Prevent CDC, Div Global Migrat & Quarantine, 1600 Clifton Rd NE,MS E-03, Atlanta, GA 30333 USA.
EM efj8@cdc.gov
FU C.E.R.
FX C.E.R. Research sponsorship was the following: During the past 2 years,
travel support for participation in rabies seminars and research support
for development of new rabies biologics via organizations that produce
rabies products. The other authors state they have no conflicts of
interest to declare.
NR 8
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U1 0
U2 1
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1195-1982
EI 1708-8305
J9 J TRAVEL MED
JI J. Travel Med.
PD JAN
PY 2014
VL 21
IS 1
BP 62
EP 66
DI 10.1111/jtm.12085
PG 5
WC Medicine, General & Internal
SC General & Internal Medicine
GA 285DC
UT WOS:000329372400013
PM 24267775
ER
PT J
AU Fenton, KA
Aquino, GA
Dean, HD
AF Fenton, Kevin A.
Aquino, Gustavo A.
Dean, Hazel D.
TI PROGRAM COLLABORATION AND SERVICE INTEGRATION IN THE PREVENTION AND
CONTROL OF HIV INFECTION, VIRAL HEPATITIS, STDs, AND TUBERCULOSIS IN THE
US: LESSONS LEARNED FROM THE FIELD
SO PUBLIC HEALTH REPORTS
LA English
DT Editorial Material
ID HEALTH; CDC
C1 [Aquino, Gustavo A.] Ctr Dis Control & Prevent CDC, Program Integrat, Atlanta, GA USA.
[Fenton, Kevin A.; Dean, Hazel D.] Ctr Dis Control & Prevent CDC, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA USA.
RP Aquino, GA (reprint author), Ctr Dis Control & Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Off Director, 1600 Clifton Rd NE,MS E-07, Atlanta, GA 30333 USA.
EM gaa1@cdc.gov
NR 28
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U1 1
U2 5
PU ASSOC SCHOOLS PUBLIC HEALTH
PI WASHINGTON
PA 1900 M ST NW, STE 710, WASHINGTON, DC 20036 USA
SN 0033-3549
J9 PUBLIC HEALTH REP
JI Public Health Rep.
PD JAN-FEB
PY 2014
VL 129
SU 1
BP 1
EP 4
PG 4
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 288BM
UT WOS:000329587000001
PM 24385642
ER
PT J
AU Will, JC
Nwaise, IA
Schieb, L
Zhong, YN
AF Will, Julie C.
Nwaise, Isaac A.
Schieb, Linda
Zhong, Yuna
TI Geographic and Racial Patterns of Preventable Hospitalizations for
Hypertension: Medicare Beneficiaries, 2004-2009
SO PUBLIC HEALTH REPORTS
LA English
DT Article
ID CARE-SENSITIVE CONDITIONS; HEALTH-CARE; RATES; DISPARITIES; POPULATION;
ASSOCIATION; ACCESS; IMPACT
AB Objectives. Hypertension as the primary reason for hospitalization is often used to indicate failure of the outpatient health-care system to prevent and control high blood pressure. Investigators have reported increased rates of these preventable hospitalizations for black people compared with white people; however, none have mapped them nationally by race.
Methods. We used Medicare Part A data to estimate preventable hypertension hospitalizations from 2004-2009 using technical specifications published by the Agency for Healthcare Research and Quality. Rates per 100,000 beneficiaries were age- and sex-standardized to 2000 U.S. Census data. We mapped county-level rates by race and identified clusters of counties with extreme rates.
Results. Black people had higher crude rates of these hospitalizations than white people for every year studied, and the test for an increasing linear time trend for the standardized rates was significant for both black and white people; that is, the gap between the races increased over time. For both races, clusters of high-rate counties occurred primarily in parts of Oklahoma, Texas, Southern Alabama, and Louisiana. High rates for white people were also found in parts of Appalachia. Large differences in rates among black and white people were found in a number of large urban areas and in parts of Florida and Alabama.
Conclusions. Racial disparities in preventable hospitalizations for hypertension persisted through 2009. The gap between black and white people is increasing, and these inequities exist unevenly across the country. Although this study was intended to be purely descriptive, future studies should use multivariate analyses to examine reasons for these unequal distributions.
C1 [Will, Julie C.; Nwaise, Isaac A.; Schieb, Linda; Zhong, Yuna] Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Div Heart Dis & Stroke Prevent, Atlanta, GA 30341 USA.
RP Will, JC (reprint author), Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Div Heart Dis & Stroke Prevent, 4770 Buford Hwy NE,MS F-72, Atlanta, GA 30341 USA.
EM jxw6@cdc.gov
RI Dalla Zuanna, Teresa/G-3133-2015
NR 34
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U1 1
U2 7
PU ASSOC SCHOOLS PUBLIC HEALTH
PI WASHINGTON
PA 1900 M ST NW, STE 710, WASHINGTON, DC 20036 USA
SN 0033-3549
J9 PUBLIC HEALTH REP
JI Public Health Rep.
PD JAN-FEB
PY 2014
VL 129
IS 1
BP 8
EP 18
PG 11
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 288BL
UT WOS:000329586900003
PM 24381355
ER
PT J
AU Okoro, CA
Stoodt, G
Rohrer, JE
Strine, TW
Li, CY
Balluz, LS
AF Okoro, Catherine A.
Stoodt, Georjean
Rohrer, James E.
Strine, Tara W.
Li, Chaoyang
Balluz, Lina S.
TI Physical Activity Patterns Among U.S. Adults with and without Serious
Psychological Distress
SO PUBLIC HEALTH REPORTS
LA English
DT Article
ID FACTOR SURVEILLANCE SYSTEM; RANDOMIZED CONTROLLED-TRIAL; HEALTH
INTERVIEW SURVEY; GENERAL-POPULATION; MENTAL-ILLNESS; DEPRESSIVE
SYMPTOMS; NATIONAL-HEALTH; OLDER-ADULTS; PRIMARY-CARE; DISORDERS
AB Objective. A physically active lifestyle is recommended for overall health both physical and mental. Serious psychological distress (SPD) is associated with adverse health behaviors. We compared patterns of physical activity (PA) among adults with and without SPD using current public health guidelines for PA and examined whether adults with SPD were physically active at recommended levels.
Methods. We used data from the 2009 Behavioral Risk Factor Surveillance System (BRFSS) to assess SPD using the Kessler 6 (K6) scale of nonspecific psychological distress and PA categories based on the 2008 U.S. Department of Health and Human Services guidelines. Complete data were available for 78,886 adults in 16 states that used an optional BRFSS mental illness and stigma module containing the K6 scale. We performed multiple logistic regression analyses to estimate prevalence ratios (PRs) and 95% confidence intervals (Cls).
Results. The unadjusted prevalence of SPD was 3.9% (95% Cl 3.6, 4.2), and the age-adjusted prevalence of SPD was 3.8% (95% Cl 3.5, 4.1). After adjusting for age, sex, race/ethnicity, education, employment, body mass index, smoking status, and heavy drinking, adults with SPD were significantly less likely to be physically active at recommended levels than adults without SPD. PRs were attenuated but remained significant after further adjustment for limitations to PA.
Conclusion. Adults with SPD are less likely to meet current PA recommendations than adults without SPD, highlighting the need for targeted interventions.
C1 [Okoro, Catherine A.; Li, Chaoyang; Balluz, Lina S.] Ctr Dis Control & Prevent, Off Surveillance Epidemiol & Lab Serv, Publ Hlth Surveillance & Informat Program Off, Div Behav Surveillance, Atlanta, GA 30333 USA.
[Stoodt, Georjean; Rohrer, James E.] Walden Univ, Coll Hlth Sci, Sch Hlth Sci, Minneapolis, MN USA.
[Strine, Tara W.] Ctr Dis Control & Prevent, Off Publ Hlth Preparedness & Response, Atlanta, GA 30333 USA.
RP Okoro, CA (reprint author), Ctr Dis Control & Prevent, Off Surveillance Epidemiol & Lab Serv, Publ Hlth Surveillance & Informat Program Off, Div Behav Surveillance, 1600 Clifton Rd NE,MS E-97, Atlanta, GA 30333 USA.
EM cokoro@cdc.gov
NR 54
TC 5
Z9 6
U1 0
U2 9
PU ASSOC SCHOOLS PUBLIC HEALTH
PI WASHINGTON
PA 1900 M ST NW, STE 710, WASHINGTON, DC 20036 USA
SN 0033-3549
J9 PUBLIC HEALTH REP
JI Public Health Rep.
PD JAN-FEB
PY 2014
VL 129
IS 1
BP 30
EP 38
PG 9
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 288BL
UT WOS:000329586900005
PM 24381357
ER
PT J
AU Harris, LEF
Toledo, L
Dunbar, E
Aquino, GA
Nesheim, SR
AF Harris, Lauren E. Fitz
Toledo, Lauren
Dunbar, Erica
Aquino, Gustavo A.
Nesheim, Steven R.
TI Program Collaboration and Service Integration Activities Among HIV
Programs in 59 US Health Departments
SO PUBLIC HEALTH REPORTS
LA English
DT Article
ID VIRAL-HEPATITIS; STD; SURVEILLANCE; PREVENTION; STATE; CDC; TB
AB Objectives. We identified the level and type of program collaboration and service integration (PCSI) among HIV prevention programs in 59 CDC-funded health department jurisdictions.
Methods. Annual progress reports (APRs) completed by all 59 health departments funded by CDC for HIV prevention activities were reviewed for collaborative and integrated activities reported by HIV programs for calendar year 2009. We identified associations between PCSI activities and funding, AIDS diagnosis rate, and organizational integration.
Results. HIV programs collaborated with other health department programs through data-related activities, provider training, and providing funding for sexually transmitted disease (STD) activities in 24 (41%), 31(53%), and 16 (27%) jurisdictions, respectively. Of the 59 jurisdictions, 57 (97%) reported integrated HIV and STD testing at the same venue, 39 (66%) reported integrated HIV and tuberculosis testing, and 26 (44%) reported integrated HIV and viral hepatitis testing. Forty-five (76%) jurisdictions reported providing integrated education/ outreach activities for HIV and at least one other disease. Twenty-six (44%) jurisdictions reported integrated partner services among HIV and STD programs. Overall, the level of PCSI activities was not associated with HIV funding, AIDS diagnoses, or organizational integration.
Conclusions. HIV programs in health departments collaborate primarily with STD programs. Key PCSI activities include integrated testing, integrated education/outreach, and training. Future assessments are needed to evaluate PCSI activities and to identify the level of collaboration and integration among prevention programs.
C1 [Harris, Lauren E. Fitz; Toledo, Lauren; Dunbar, Erica; Aquino, Gustavo A.; Nesheim, Steven R.] Ctr Dis Control & Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA 30333 USA.
[Harris, Lauren E. Fitz; Toledo, Lauren] ICF Int, Atlanta, GA USA.
RP Harris, LEF (reprint author), Ctr Dis Control & Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, 1600 Clifton Rd NE,MS E-45, Atlanta, GA 30333 USA.
EM lfitzharris@cdc.gov
NR 19
TC 4
Z9 4
U1 1
U2 1
PU ASSOC SCHOOLS PUBLIC HEALTH
PI WASHINGTON
PA 1900 M ST NW, STE 710, WASHINGTON, DC 20036 USA
SN 0033-3549
J9 PUBLIC HEALTH REP
JI Public Health Rep.
PD JAN-FEB
PY 2014
VL 129
SU 1
BP 33
EP 42
PG 10
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 288BM
UT WOS:000329587000006
ER
PT J
AU Hunter, P
Oyervides, O
Grande, KM
Prater, D
Vann, V
Reitl, I
Biedrzycki, PA
AF Hunter, Paul
Oyervides, Otilio
Grande, Katarina M.
Prater, Daphne
Vann, Vannessa
Reitl, Irmine
Biedrzycki, Paul A.
TI Facebook-Augmented Partner Notification in a Cluster of Syphilis Cases
in Milwaukee
SO PUBLIC HEALTH REPORTS
LA English
DT Article
ID SEXUALLY-TRANSMITTED-DISEASES; INTERNET; HIV; MEN; SEX; NETWORK;
SURVEILLANCE; PREVENTION
AB Public health professionals face many challenges in infectious disease cluster case identification and partner notification (PN), especially in populations using social media as a primary communication venue. We present a method using Facebook and social network diagram illustration to identify, link, and notify individuals in a cluster of syphilis cases in young black men who have sex with men (MSM). Use of Facebook was crucial in identifying two of 55 individuals with syphilis, and the cooperation of socially connected individuals with traditional PN methods yielded a high number of contacts per case. Integration of PN services for HIV and sexually transmitted diseases, as well as collaboration between the city and state information systems, assisted in the cluster investigation. Given that rates of syphilis and HIV infection are increasing significantly in young African American MSM, the use of social media can provide an additional avenue to facilitate case identification and notification.
C1 [Hunter, Paul] Univ Wisconsin, Sch Med & Publ Hlth, Madison, WI USA.
[Hunter, Paul; Oyervides, Otilio; Grande, Katarina M.; Prater, Daphne; Vann, Vannessa; Reitl, Irmine; Biedrzycki, Paul A.] City Milwaukee Hlth Dept, Milwaukee, WI 53202 USA.
[Oyervides, Otilio] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Grande, Katarina M.] Univ Wisconsin, Populat Hlth Inst, Madison, WI USA.
RP Hunter, P (reprint author), City Milwaukee Hlth Dept, 841 N Broadway 315, Milwaukee, WI 53202 USA.
EM phunte@milwaukee.gov
NR 32
TC 9
Z9 9
U1 2
U2 12
PU ASSOC SCHOOLS PUBLIC HEALTH
PI WASHINGTON
PA 1900 M ST NW, STE 710, WASHINGTON, DC 20036 USA
SN 0033-3549
J9 PUBLIC HEALTH REP
JI Public Health Rep.
PD JAN-FEB
PY 2014
VL 129
SU 1
BP 43
EP 49
PG 7
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 288BM
UT WOS:000329587000007
PM 24385648
ER
PT J
AU Viner, K
Perella, D
Lopez, A
Bialek, S
Nguyen, M
Spells, N
Watson, B
AF Viner, Kendra
Perella, Dana
Lopez, Adriana
Bialek, Stephanie
Nguyen, Michael
Spells, Niya
Watson, Barbara
TI Comparing Active and Passive Varicella Surveillance in Philadelphia,
2005-2010: Recommendations for the Transition to Nationwide Passive
Varicella Disease Surveillance
SO PUBLIC HEALTH REPORTS
LA English
DT Article
AB Objective. The Philadelphia Department of Public Health (PDPH) conducts active surveillance for varicella in West Philadelphia. For its approximately 300 active surveillance sites, PDPH mandates biweekly reports of varicella (including zero cases) and performs intensive case investigations. Elsewhere in Philadelphia, surveillance sites passively report varicella cases, and abbreviated investigations are conducted. We used active varicella surveillance program data to inform the transition to nationwide passive varicella surveillance.
Methods. We compared classification of reported cases, varicella disease incidence, and reporting completeness for active and passive surveillance areas for 2005-2010. We assessed reporting completeness using capture-recapture analysis of 2- to 18-year-old cases reported by schools/daycare centers and health-care providers.
Results. From 2005 to 2010, PDPH received 3,280 passive and 969 active surveillance varicella case reports. Most passive surveillance reports were classified as probable cases (18% confirmed, 56% probable, and 26% excluded), whereas nearly all of the active surveillance reports were either confirmed or excluded (36% confirmed, 11% probable, and 53% excluded). Overall incidence rates calculated using confirmed/probable cases were similar in the active and passive surveillance areas. Detection of laboratory-confirmed, breakthrough, and moderate-to-severe cases was equivalent for both surveillance areas.
Conclusions. Although active surveillance for varicella results in better classified cases, passive surveillance provides comparable data for monitoring disease trends in breakthrough and moderate-to-severe varicella. To further improve passive surveillance in the two-dose-varicella vaccine era, jurisdictions should consider conducting periodic enhanced surveillance, encouraging laboratory testing, and collecting additional varicella-specific variables for passive surveillance.
C1 [Viner, Kendra; Perella, Dana; Spells, Niya; Watson, Barbara] Philadelphia Dept Publ Hlth, Philadelphia, PA 19146 USA.
[Lopez, Adriana; Bialek, Stephanie] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Nguyen, Michael] US FDA, Rockville, MD 20857 USA.
RP Viner, K (reprint author), Philadelphia Dept Publ Hlth, Div Dis Control, 500 S Broad St, Philadelphia, PA 19146 USA.
EM kendra.viner@phila.gov
NR 15
TC 0
Z9 0
U1 0
U2 0
PU ASSOC SCHOOLS PUBLIC HEALTH
PI WASHINGTON
PA 1900 M ST NW, STE 710, WASHINGTON, DC 20036 USA
SN 0033-3549
J9 PUBLIC HEALTH REP
JI Public Health Rep.
PD JAN-FEB
PY 2014
VL 129
IS 1
BP 47
EP 54
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 288BL
UT WOS:000329586900007
PM 24381359
ER
PT J
AU Hutton, HE
Chander, G
Green, PP
Hutsell, CA
Weingarten, K
Peterson, KL
AF Hutton, Heidi E.
Chander, Geetanjali
Green, Patricia P.
Hutsell, Catherine A.
Weingarten, Kimberly
Peterson, Karen L.
TI A Novel Integration Effort to Reduce the Risk for Alcohol-Exposed
Pregnancy Among Women Attending Urban STD Clinics
SO PUBLIC HEALTH REPORTS
LA English
DT Article
ID SEXUALLY-TRANSMITTED-DISEASES; RANDOMIZED CONTROLLED-TRIAL; MOTIVATIONAL
INTERVENTION; CHILDBEARING AGE; ADOLESCENTS; PREVENTION; CARE;
INFECTION; DISORDERS; BEHAVIORS
AB Alcohol-exposed pregnancy (AEP) is a significant public health Problem in the United States. Sexually transmitted disease (STD) clinics serve female clients with a high prevalence of heavy alcohol consumption coupled with ineffective contraceptive use. Project CHOICES (Changing High-Rik AlcOhol Use and Increasing Contraception Effectiveness) is an evidence-based, brief intervention to lower risk of AEP by targeting alcohol and contraceptive behaviors through motivational interviewing and individualized feedback. We describe our experience integrating and implementing CHOICES in STD clinics. This endeavor aligns with CDC's National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention's program collaboration and service integration strategic priority to strengthen collaborative work across disease areas and integrate services provided by related programs at the client level.
C1 [Hutton, Heidi E.] Johns Hopkins Univ, Sch Med, Dept Psychiat & Behav Sci, AIDS Psychiat Serv, Baltimore, MD USA.
[Chander, Geetanjali] Johns Hopkins Univ, Sch Med, Div Gen Internal Med, Baltimore, MD USA.
[Green, Patricia P.; Hutsell, Catherine A.] Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, Prevent Res Branch, Atlanta, GA USA.
[Weingarten, Kimberly] Druid STD Clin, Baltimore City Hlth Dept, Baltimore, MD USA.
[Peterson, Karen L.] Denver Publ Hlth, Denver, CO 80204 USA.
RP Peterson, KL (reprint author), Denver Publ Hlth, 605 Bannock St, Denver, CO 80204 USA.
EM kpeterso@dhha.org
NR 28
TC 5
Z9 5
U1 1
U2 10
PU ASSOC SCHOOLS PUBLIC HEALTH
PI WASHINGTON
PA 1900 M ST NW, STE 710, WASHINGTON, DC 20036 USA
SN 0033-3549
J9 PUBLIC HEALTH REP
JI Public Health Rep.
PD JAN-FEB
PY 2014
VL 129
SU 1
BP 56
EP 62
PG 7
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 288BM
UT WOS:000329587000009
PM 24385650
ER
PT J
AU Elmore, K
Nelson, R
Gant, Z
Jeffries, C
Broeker, L
Mirabito, M
Roberts, H
AF Elmore, Kim
Nelson, Rob
Gant, Zanetta
Jeffries, Carla
Broeker, Lance
Mirabito, Massimo
Roberts, Henry
TI Data Harmonization Process for Creating the National Center for
HIV/AIDS, Viral Hepatitis, STD, and TB Prevention Atlas
SO PUBLIC HEALTH REPORTS
LA English
DT Article
AB In 2009, the CDC National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) initiated the online, interactive NCHHSTP Atlas. The goal of the Atlas is to strengthen the capacity to monitor the diseases overseen by NCHHSTP and to illustrate demographic, spatial, and temporal variation in disease patterns. The Atlas includes HIV, AIDS, viral hepatitis, sexually transmitted disease, and tuberculosis surveillance data, and aims to provide a single point of access to meet the analytical and data dissemination needs of NCHHSTP. To accoMplish this goal, an NCHHSTP-wide Data Harmonization Workgroup reviewed surveillance data collected by each division to harmonize the data across diseases, allowing one to query data and generate comparable maps and tables via the same user interface. Although we were not able to harmonize all data elements, data standardization is necessary and work continues toward that goal.
C1 [Elmore, Kim; Gant, Zanetta] Ctr Dis Control & Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Div HIV AIDS Prevent, Atlanta, GA 30333 USA.
[Nelson, Rob] Ctr Dis Control & Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Div STD Prevent, Atlanta, GA 30333 USA.
[Jeffries, Carla] Northrop Grumman Corp, Falls Church, VA USA.
[Broeker, Lance; Mirabito, Massimo] Agcy Tox Subst & Dis Registry, Geospatial Res Anal & Serv Program, Atlanta, GA USA.
[Roberts, Henry] Ctr Dis Control & Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Div Viral Hepatitis, Atlanta, GA 30333 USA.
RP Elmore, K (reprint author), Ctr Dis Control & Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, 1600 Clifton Rd NE,MS E48, Atlanta, GA 30333 USA.
EM kelmore@cdc.gov
NR 16
TC 2
Z9 2
U1 0
U2 4
PU ASSOC SCHOOLS PUBLIC HEALTH
PI WASHINGTON
PA 1900 M ST NW, STE 710, WASHINGTON, DC 20036 USA
SN 0033-3549
J9 PUBLIC HEALTH REP
JI Public Health Rep.
PD JAN-FEB
PY 2014
VL 129
SU 1
BP 63
EP 69
PG 7
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 288BM
UT WOS:000329587000010
PM 24385651
ER
PT J
AU Mitruka, K
Blake, H
Ricks, P
Miramontes, R
Bamrah, S
Chee, C
Hickstein, L
AF Mitruka, Kren
Blake, Haley
Ricks, Philip
Miramontes, Roque
Bamrah, Sapna
Chee, Carla
Hickstein, Laurie
TI A Tuberculosis Outbreak Fueled by Cross-Border Travel and Illicit
Substances: Nevada and Arizona
SO PUBLIC HEALTH REPORTS
LA English
DT Article
ID UNDOCUMENTED FOREIGN-BORN; UNITED-STATES; PUBLIC-HEALTH; TRANSMISSION;
SURVEILLANCE; IMMIGRATION; FAILURE; USERS
AB Objectives. From May 2006 to August 2008, the Southern Nevada Health District identified eight tuberculosis (TB) cases in six adults and two children in a Hispanic community. We conducted an outbreak investigation to determine the extent of TB transmission and prevent additional cases.
Methods. We investigated TB cases in Nevada and Arizona with the outbreak genotype or cases with suspected epidemiologic links to this cluster but without genotyping data. We reviewed medical records and interviewed patients and contacts. Subsequently, genotype surveillance was conducted for approximately four years to monitor additional outbreak-related cases.
Results. Eight outbreak cases were identified among six adults and two children. All patients were Hispanic and five were U.S.-born. The index patient was diagnosed while detained in Immigration and Customs Enforcement custody but deported before treatment completion. He was lost to follow-up for two years, during which time he served as the source for six secondary TB cases, including his own child. Along with the index patient, five patients reportedly engaged in the sale or use of methamphetamine. Follow-up surveillance in the two states identified eight additional cases with the outbreak genotype; three had epidemiologic links to the index case.
Conclusions. We found that incomplete TB treatment led to extensive TB transmission. We recommend thorough discharge planning and active measures to ensure continuity of care and TB treatment completion for people in custody at higher risk for loss to follow-up, which likely includes those engaged in the sale or use of illicit substances.
C1 [Mitruka, Kren; Ricks, Philip; Miramontes, Roque; Bamrah, Sapna] Ctr Dis Control & Prevent, Div TB Eliminat, Atlanta, GA 30333 USA.
[Blake, Haley; Hickstein, Laurie] Southern Nevada Hlth Dist, TB Treatment & Control Clin, Las Vegas, NV USA.
[Chee, Carla] Arizona Dept Hlth Serv, Phoenix, AZ 85007 USA.
RP Mitruka, K (reprint author), Ctr Dis Control & Prevent, Div TB Eliminat, Surveillance Epidemiol & Outbreak Invest Branch, 1600 Clifton Rd NE,MS G-37, Atlanta, GA 30333 USA.
EM kmitruka@cdc.gov
NR 34
TC 1
Z9 1
U1 0
U2 2
PU ASSOC SCHOOLS PUBLIC HEALTH
PI WASHINGTON
PA 1900 M ST NW, STE 710, WASHINGTON, DC 20036 USA
SN 0033-3549
J9 PUBLIC HEALTH REP
JI Public Health Rep.
PD JAN-FEB
PY 2014
VL 129
IS 1
BP 78
EP 85
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 288BL
UT WOS:000329586900011
PM 24381363
ER
PT J
AU Skinner, JM
Distefano, J
Warrington, J
Bailey, SR
Winscott, M
Taylor, MM
AF Skinner, Julia M.
Distefano, Jana
Warrington, Jennifer
Bailey, S. Robert
Winscott, Michelle
Taylor, Melanie M.
TI Trends in Reported Syphilis and Gonorrhea Among HIV-Infected People in
Arizona: Implications for Prevention and Control
SO PUBLIC HEALTH REPORTS
LA English
DT Article
ID SEXUALLY-TRANSMITTED INFECTIONS; MEN; RISK; SEX; TRANSMISSION;
CHLAMYDIA; DISEASES
AB Objective. HIV and sexually transmitted disease (STD) surveillance patterns in Arizona suggested the need for integrated data analyses to identify trends.
Methods. We compiled all HIV/AIDS cases diagnosed from 1998 to 2008 that were reported in Arizona and syphilis or gonorrhea cases diagnosed from 1998 to 2008 in Arizona. We used deterministic matching to identify individuals who were diagnosed with HIV and one or more STDs, and calculated time intervals between diagnoses.
Results. Of 23,940 people with HIV/AIDS reported from 1998 to 2008, 1,899. (2.6%) had at leak one syphilis or gonorrhea diagnosis from 1998 to 2008. Approximately 85% of these cases reported male-to-male sexual contact. Among males with syphilis, HIV coinfection increased from 0.5% in 1998 to 29.1% in 2008. Among males with gonorrhea, HIV coinfection increased from 2.0% in 1998 to 3.1% in 2008. Among HIV-cases diagnosed from 2004 to 2008 and reported with at least one syphilis or gonorrhea diagnosis, the majority of syphilis cases (76.1%) were diagnosed at or after HIV diagnosis, whereas a majority of gonorrhea cases (54.9%) were diagnosed prior to HIV diagnosis.
Conclusion. Use of the deterministic matching method identified increases in STD infections among HIV-infected people. The routine performance of this cross-matching method may be a useful tool in identifying these high-risk individuals so that targeted partner services and appropriate care referrals may be used in a timely fashion.
C1 [Skinner, Julia M.; Distefano, Jana; Warrington, Jennifer; Bailey, S. Robert] Arizona Dept Hlth Serv, HIV Surveillance Program, Phoenix, AZ 85007 USA.
[Winscott, Michelle] Mayo Clin, Scottsdale, AZ USA.
[Taylor, Melanie M.] Ctr Dis Control & Prevent, Div STD Prevent, Atlanta, GA USA.
[Taylor, Melanie M.] Arizona Dept Hlth Serv, STD Control Program, Phoenix, AZ 85007 USA.
RP Skinner, JM (reprint author), Arizona Dept Hlth Serv, HIV Surveillance Program, 150 N 18th Ave,Ste 110, Phoenix, AZ 85007 USA.
EM julia.skinner@azdhs.gov
NR 27
TC 4
Z9 4
U1 0
U2 3
PU ASSOC SCHOOLS PUBLIC HEALTH
PI WASHINGTON
PA 1900 M ST NW, STE 710, WASHINGTON, DC 20036 USA
SN 0033-3549
J9 PUBLIC HEALTH REP
JI Public Health Rep.
PD JAN-FEB
PY 2014
VL 129
SU 1
BP 85
EP 94
PG 10
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 288BM
UT WOS:000329587000013
PM 24385654
ER
PT J
AU Peterson, C
Grosse, SD
Glidewell, J
Garg, LF
Van Naarden, K
Knapp, MM
Beres, LM
Hinton, CF
Olney, RS
Cassell, CH
AF Peterson, Cora
Grosse, Scott D.
Glidewell, Jill
Garg, Lorraine F.
Van Naarden, Kim
Knapp, Mary M.
Beres, Leslie M.
Hinton, Cynthia F.
Olney, Richard S.
Cassell, Cynthia H.
TI A Public Health Economic Assessment of Hospitals' Cost to Screen
Newborns for Critical Congenital Heart Disease
SO PUBLIC HEALTH REPORTS
LA English
DT Article
ID PULSE OXIMETRY; ASYMPTOMATIC NEWBORNS; DEFECTS; INFANTS; STRATEGIES;
ACCURACY; MODEL
AB Objective. Critical congenital heart disease (CCHD) was recently added to the U.S. Recommended Uniform Screening Panel for newborns. This evaluation aimed to estimate screening time and hospital cost per, newborn screened for CCHD using pulse oximetry as part of a public health economic assessment of CCHD screening.
Methods. A cost survey and time and motion study were conducted in well-newborn and special/intensive care nurseries in a random sample of seven birthing hospitals in New Jersey, where the state legislature mandated CCHD screening in 2011. The sample was stratified by hospital facility level, hospital birth census, and geographic location. At the time of the evaluation, all hospitals had conducted CCHD screening for at least four months.
Results. Mean screening time per newborn was 9.1 (standard deviation = 3.4) minutes. Hospitals' total mean estimated cost per newborn screened was $14.19 (in 2011 U.S. dollars), consisting of $7.36 in labor costs and $6.83 in equipment and supply costs.
Conclusions. This federal agency-state health department collaborative assessment is the first state-level analysis of time and hospital costs for CCHD screening using pulse oximetry conducted in the U.S. Hospitals' cost per newborn screened for CCHD with pulse oximetry is comparable with cost estimates of existing newborn screening tests. Hospitals' equipment costs varied substantially based on the pulse oximetry technology employed, with lower costs among hospitals that used reusable screening sensors. In combination with estimates of screening accuracy, effectiveness, and avoided costs, information from this evaluation suggests that CCHD screening is cost-effective.
C1 [Peterson, Cora; Grosse, Scott D.; Glidewell, Jill; Van Naarden, Kim; Hinton, Cynthia F.; Olney, Richard S.; Cassell, Cynthia H.] Ctr Dis Control & Prevent, Natl Ctr Injury Prevent & Control, Atlanta, GA 30341 USA.
[Garg, Lorraine F.; Knapp, Mary M.; Beres, Leslie M.] New Jersey State Dept Hlth, Div Family Hlth Serv Special Child Hlth & Early I, Trenton, NJ 08625 USA.
RP Peterson, C (reprint author), Ctr Dis Control & Prevent, Natl Ctr Injury Prevent & Control, 4770 Buford Hwy,MS F-62, Atlanta, GA 30341 USA.
EM cora.peterson@cdc.hhs.gov
OI Peterson, Cora/0000-0001-7955-0977
NR 23
TC 10
Z9 10
U1 0
U2 4
PU ASSOC SCHOOLS PUBLIC HEALTH
PI WASHINGTON
PA 1900 M ST NW, STE 710, WASHINGTON, DC 20036 USA
SN 0033-3549
J9 PUBLIC HEALTH REP
JI Public Health Rep.
PD JAN-FEB
PY 2014
VL 129
IS 1
BP 86
EP 93
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 288BL
UT WOS:000329586900012
PM 24381364
ER
PT J
AU Maulsby, C
Millett, G
Lindsey, K
Kelley, R
Johnson, K
Montoya, D
Holtgrave, D
AF Maulsby, Cathy
Millett, Greg
Lindsey, Kali
Kelley, Robin
Johnson, Kim
Montoya, Daniel
Holtgrave, David
TI HIV Among Black Men Who Have Sex with Men (MSM) in the United States: A
Review of the Literature
SO AIDS AND BEHAVIOR
LA English
DT Review
DE Black men who have sex with men; HIV/AIDS; HIV; Men who have sex with
men; Health disparity
ID AFRICAN-AMERICAN MEN; NEW-YORK-CITY; ACTIVE ANTIRETROVIRAL THERAPY;
MULTICENTER AIDS COHORT; UNPROTECTED ANAL INTERCOURSE; OLDER PARTNER
SELECTION; HEALTH-SERVICE USE; CONSPIRACY BELIEFS; MALE CIRCUMCISION;
RISK BEHAVIORS
AB In 2006, Millett published a seminal literature review that examined 12 hypotheses to explain the high rates of HIV among black MSM. This paper augments Millett's article by reviewing the recent literature on behavioral, biomedical, structural, social contextual, psychosocial, and social network factors that affect HIV rates among black MSM. We searched three databases: PubMed, Scopus, and Google Scholar. First we searched all articles that included black or African American and MSM and HIV. We then searched the following terms for each area: behavioral (drug use during sex, crack cocaine use, and serosorting); biomedical (circumcision, STDs, and STIs); structural (access to care, HIV care, ART, HAART, patient-provider communication, HIV quality of care); social contextual (stigma, discrimination, internalized homophobia, internalized heterosexism, medical mistrust, social isolation, and incarceration); psychosocial (peer support and mental health); and social network (sexual mixing, partner characteristics, and social networks) factors. We identified 39 articles to include in this review. We found inconclusive evidence that incarceration, stigma, discrimination, social isolation, mental health disparities, or social networks explain the elevated rates of HIV among black MSM. We found evidence that the differences in rates of HIV between black and white MSM may be explained by differences in STIs, undiagnosed seropositivity, access to care and treatment services, and use of HAART. There is an overwhelming need for HIV testing, linkage to care, retention in care, and adherence programs for black MSM.
C1 [Maulsby, Cathy; Holtgrave, David] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Hlth Behav & Soc, Baltimore, MD 21205 USA.
[Millett, Greg] Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA USA.
[Lindsey, Kali; Kelley, Robin; Johnson, Kim; Montoya, Daniel] Natl Minor AIDS Council, Washington, DC USA.
RP Maulsby, C (reprint author), Johns Hopkins Bloomberg Sch Publ Hlth, Dept Hlth Behav & Soc, 624 N Broadway,STE 904C, Baltimore, MD 21205 USA.
EM cmaulsby@jhsph.edu
NR 115
TC 61
Z9 61
U1 4
U2 41
PU SPRINGER/PLENUM PUBLISHERS
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1090-7165
EI 1573-3254
J9 AIDS BEHAV
JI AIDS Behav.
PD JAN
PY 2014
VL 18
IS 1
BP 10
EP 25
DI 10.1007/s10461-013-0476-2
PG 16
WC Public, Environmental & Occupational Health; Social Sciences, Biomedical
SC Public, Environmental & Occupational Health; Biomedical Social Sciences
GA 284LB
UT WOS:000329317700002
PM 23620241
ER
PT J
AU Guo, YQ
Alderisio, KA
Yang, WL
Cama, V
Feng, YY
Xiao, LH
AF Guo, Yaqiong
Alderisio, Kerri A.
Yang, Wenli
Cama, Vitaliano
Feng, Yaoyu
Xiao, Lihua
TI Host Specificity and Source of Enterocytozoon bieneusi Genotypes in a
Drinking Source Watershed
SO APPLIED AND ENVIRONMENTAL MICROBIOLOGY
LA English
DT Article
ID HUMAN WATERBORNE PATHOGENS; EASTERN UNITED-STATES; MOLECULAR
CHARACTERIZATION; CRYPTOSPORIDIUM GENOTYPES; CYCLOSPORA-CAYETANENSIS;
GIARDIA-DUODENALIS; DAIRY-CATTLE; WASTE-WATER; NEW-YORK;
MICROSPORIDIOSIS
AB To assess the host specificity of Enterocytozoon bieneusi and to track the sources of E. bieneusi contamination, we genotyped E. bieneusi in wildlife and stormwater from the watershed of New York City's source water, using ribosomal internal transcribed spacer (ITS)-based PCR and sequence analyses. A total of 255 specimens from 23 species of wild mammals and 67 samples from stormwater were analyzed. Seventy-four (29.0%) of the wildlife specimens and 39 (58.2%) of the stormwater samples from streams were PCR positive. Altogether, 20 E. bieneusi genotypes were found, including 8 known genotypes and 12 new ones. Sixteen and five of the genotypes were seen in animals and stormwater from the watershed, respectively, with WL4 being the most common genotype in both animals (35 samples) and stormwater (23 samples). The 20 E. bieneusi genotypes belonged to five genogroups (groups 1, 3, 4, and 7 and an outlier), with only 23/113 (20.4%) E. bieneusi-positive samples belonging to zoonotic genogroup 1 and 3/20 genotypes ever being detected in humans. The two genogroups previously considered host specific, groups 3 and 4, were both detected in multiple groups of mammals. Thus, with the exception of the type IV, Peru11, and D genotypes, which were detected in only 7, 5, and 2 animals, respectively, most E. bieneusi strains in most wildlife samples and all stormwater samples in the watershed had no known public health significance, as these types have not previously been detected in humans. The role of different species of wild mammals in the contribution of E. bieneusi contamination in stormwater was supported by determinations of host-adapted Cryptosporidium species/genotypes in the same water samples. Data from this study indicate that the host specificity of E. bieneusi group 3 is broader than originally thought, and wildlife is the main source of E. bieneusi in stormwater in the watershed.
C1 [Guo, Yaqiong; Feng, Yaoyu] E China Univ Sci & Technol, Sch Resources & Environm Engn, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China.
[Guo, Yaqiong; Yang, Wenli; Xiao, Lihua] Ctr Dis Control & Prevent, Div Foodborne Waterborne & Environm Dis, Atlanta, GA USA.
[Alderisio, Kerri A.] New York City Dept Environm Protect, Valhalla, NY USA.
[Cama, Vitaliano] Ctr Dis Control & Prevent, Div Parasit Dis & Malaria, Atlanta, GA USA.
RP Feng, YY (reprint author), E China Univ Sci & Technol, Sch Resources & Environm Engn, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China.
EM yyfeng@ecust.edu.cn
RI Xiao, Lihua/B-1704-2013; Feng, Yaoyu/B-3076-2014; Yaqiong,
Guo/N-4927-2015
OI Xiao, Lihua/0000-0001-8532-2727;
FU National Natural Science Foundation of China [31229005, 31110103901];
Fundamental Research Funds for the Central Universities, China; National
Special Fund for the State Key Laboratory of Bioreactor Engineering
[2060204]; Centers for Disease Control and Prevention
FX This work was supported by the National Natural Science Foundation of
China (grants 31229005 and 31110103901); Fundamental Research Funds for
the Central Universities, China; the National Special Fund for the State
Key Laboratory of Bioreactor Engineering (no. 2060204); and the Centers
for Disease Control and Prevention.
NR 36
TC 32
Z9 33
U1 1
U2 9
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0099-2240
EI 1098-5336
J9 APPL ENVIRON MICROB
JI Appl. Environ. Microbiol.
PD JAN
PY 2014
VL 80
IS 1
BP 218
EP 225
DI 10.1128/AEM.02997-13
PG 8
WC Biotechnology & Applied Microbiology; Microbiology
SC Biotechnology & Applied Microbiology; Microbiology
GA 277XA
UT WOS:000328851400023
PM 24141128
ER
PT J
AU Stowell, JD
Forlin-Passoni, D
Radford, K
Bate, SL
Dollard, SC
Bialek, SR
Cannon, MJ
Schmid, DS
AF Stowell, Jennifer D.
Forlin-Passoni, Daniela
Radford, Kay
Bate, Sheri L.
Dollard, Sheila C.
Bialek, Stephanie R.
Cannon, Michael J.
Schmid, D. Scott
TI Cytomegalovirus Survival and Transferability and the Effectiveness of
Common Hand-Washing Agents against Cytomegalovirus on Live Human Hands
SO APPLIED AND ENVIRONMENTAL MICROBIOLOGY
LA English
DT Article
ID DAY-CARE-CENTER; INFECTION; TRANSMISSION; DISEASE; EFFICACY; VIRUS; RISK
AB Congenital cytomegalovirus (CMV) transmission can occur when women acquire CMV while pregnant. Infection control guidelines may reduce risk for transmission. We studied the duration of CMV survival after application of bacteria to the hands and after transfer from the hands to surfaces and the effectiveness of cleansing with water, regular and antibacterial soaps, sanitizer, and diaper wipes. Experiments used CMV AD169 in saliva at initial titers of 1 x 10(5) infectious particles/ml. Samples from hands or surfaces (points between 0 and 15 min) were placed in culture and observed for at least 2 weeks. Samples were also tested using CMV real-time PCR. After application of bacteria to the hands, viable CMV was recovered from 17/20 swabs at 0 min, 18/20 swabs at 1 min, 5/20 swabs at 5 min, and 4/20 swabs at 15 min. After transfer, duration of survival was at least 15 min on plastic (1/2 swabs), 5 min on crackers and glass (3/4 swabs), and 1 min or less on metal and cloth (3/4 swabs); no viable virus was collected from wood, rubber, or hands. After cleansing, no viable virus was recovered using water (0/22), plain soap (0/20), antibacterial soap (0/20), or sanitizer (0/22). Viable CMV was recovered from 4/20 hands 10 min after diaper wipe cleansing. CMV remains viable on hands for sufficient times to allow transmission. CMV may be transferred to surfaces with reduced viability. Hand-cleansing methods were effective at eliminating viable CMV from hands.
C1 [Stowell, Jennifer D.; Cannon, Michael J.] Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA USA.
[Forlin-Passoni, Daniela; Radford, Kay; Bate, Sheri L.; Dollard, Sheila C.; Bialek, Stephanie R.; Schmid, D. Scott] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Viral Dis, Atlanta, GA 30329 USA.
RP Schmid, DS (reprint author), Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Viral Dis, Atlanta, GA 30329 USA.
EM SSchmid@cdc.gov
FU Centers for Disease Control and Prevention; CAPES
FX This research was supported in part by appointments (J.D.S., D.F.-P.,
and S.L.B.) at the Centers for Disease Control and Prevention
administered by the Oak Ridge Institute for Science and Education
through an interagency agreement between the U.S. Department of Energy
and the CDC. Additional funding for D.F.-P. was provided by CAPES
through an agreement between the Brazilian Ministry of Education and
UNIFESP, Sao Paulo, Brazil.
NR 27
TC 7
Z9 7
U1 2
U2 31
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0099-2240
EI 1098-5336
J9 APPL ENVIRON MICROB
JI Appl. Environ. Microbiol.
PD JAN
PY 2014
VL 80
IS 2
BP 455
EP 461
DI 10.1128/AEM.03262-13
PG 7
WC Biotechnology & Applied Microbiology; Microbiology
SC Biotechnology & Applied Microbiology; Microbiology
GA 282QK
UT WOS:000329187100004
PM 24185855
ER
PT J
AU Purcell, DW
Mizuno, Y
Smith, DK
Grabbe, K
Courtenay-Quirk, C
Tomlinson, H
Mermin, J
AF Purcell, David W.
Mizuno, Yuko
Smith, Dawn K.
Grabbe, Kristina
Courtenay-Quirk, Cari
Tomlinson, Hank
Mermin, Jonathan
TI Incorporating Couples-Based Approaches into HIV Prevention for Gay and
Bisexual Men: Opportunities and Challenges
SO ARCHIVES OF SEXUAL BEHAVIOR
LA English
DT Article
DE HIV; Men who have sex with men; Couples counseling; Gay; Bisexual;
Sexual orientation
ID UNPROTECTED ANAL INTERCOURSE; SEXUAL RISK BEHAVIOR; PREEXPOSURE
PROPHYLAXIS; SERODISCORDANT COUPLES; DISCORDANT COUPLES; SECONDARY
SYPHILIS; NEGOTIATED SAFETY; LIMITED KNOWLEDGE; RANDOMIZED-TRIAL;
HOMOSEXUAL-MEN
AB Thirty years after the beginning of the HIV epidemic, gay, bisexual, and other men who have sex with men (collectively called MSM) bear a disproportionate burden of HIV in the United States and continue to acquire a distressingly high number and proportion of new infections. Historically, HIV prevention for MSM has been focused on individual-level behavior change, rarely intervening with MSM as part of a couple. Yet, an estimated 33-67 % of HIV infections among MSM are acquired from primary sexual partners, suggesting that work with MSM as couples could be an important contributor to prevention. Given the emergence of high impact combination HIV prevention, it is timely to consider how work with the broad variety of male couples can improve both personal and community health. Couples HIV testing and counseling for MSM is an important advance for identifying men who are unaware that they are HIV-positive, identifying HIV-discordant couples, and supporting men who want to learn their HIV status with their partner. Once men know their HIV status, new advances in biomedical prevention, which can dramatically reduce risk of HIV transmission or acquisition, allow men to make prevention decisions that can protect themselves and their partners. This paper highlights the present-day challenges and benefits of using a couples-based approach with MSM in the era of combination prevention to increase knowledge of HIV status, increase identification of HIV discordant couples to improve targeting prevention services, and support mutual disclosure of HIV status.
C1 [Purcell, David W.; Mizuno, Yuko; Smith, Dawn K.; Grabbe, Kristina; Tomlinson, Hank] Ctr Dis Control & Prevent, Div HIV AIDS Prevent MS D 21, Atlanta, GA 30333 USA.
[Courtenay-Quirk, Cari] Ctr Dis Control & Prevent, Div Global HIV AIDS, Atlanta, GA 30333 USA.
[Mermin, Jonathan] Ctr Dis Control & Prevent, Natl Ctr HIV Viral Hepatitis STD & TB Prevent, Atlanta, GA 30333 USA.
RP Purcell, DW (reprint author), Ctr Dis Control & Prevent, Div HIV AIDS Prevent MS D 21, 1600 Clifton Rd, Atlanta, GA 30333 USA.
EM dhp8@cdc.gov
OI Purcell, David/0000-0001-8125-5168
FU Intramural CDC HHS [CC999999]
NR 103
TC 10
Z9 10
U1 4
U2 13
PU SPRINGER/PLENUM PUBLISHERS
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0004-0002
EI 1573-2800
J9 ARCH SEX BEHAV
JI Arch. Sex. Behav.
PD JAN
PY 2014
VL 43
IS 1
BP 35
EP 46
DI 10.1007/s10508-013-0205-y
PG 12
WC Psychology, Clinical; Social Sciences, Interdisciplinary
SC Psychology; Social Sciences - Other Topics
GA 283HL
UT WOS:000329236900008
PM 24233328
ER
PT J
AU Adachi, K
Coleman, MS
Khan, N
Jentes, ES
Arguin, P
Rao, SR
LaRocque, RC
Sotir, MJ
Brunette, G
Ryan, ET
Meltzer, MI
AF Adachi, Kenji
Coleman, Margaret S.
Khan, Nomana
Jentes, Emily S.
Arguin, Paul
Rao, Sowmya R.
LaRocque, Regina C.
Sotir, Mark J.
Brunette, Gary
Ryan, Edward T.
Meltzer, Martin I.
CA Global TravEpiNet Consortium
TI Economics of Malaria Prevention in US Travelers to West Africa
SO CLINICAL INFECTIOUS DISEASES
LA English
DT Article
DE costs; benefits; malaria prevention; pretravel health consultation
ID COST-EFFECTIVENESS ANALYSIS; INTERNATIONAL TRAVELERS; UNITED-STATES;
CHEMOPROPHYLAXIS; PROPHYLAXIS; KENYA
AB Background. Pretravel health consultations help international travelers manage travel-related illness risks through education, vaccination, and medication. This study evaluated costs and benefits of that portion of the health consultation associated with malaria prevention provided to US travelers bound for West Africa.
Methods. The estimated change in disease risk and associated costs and benefits resulting from traveler adherence to malaria chemoprophylaxis were calculated from 2 perspectives: the healthcare payer's and the traveler's. We used data from the Global TravEpiNet network of US travel clinics that collect de-identified pretravel data for international travelers. Disease risk and chemoprophylaxis effectiveness were estimated from published medical reports. Direct medical costs were obtained from the Nationwide Inpatient Sample and published literature.
Results. We analyzed 1029 records from January 2009 to January 2011. Assuming full adherence to chemoprophylaxis regimens, consultations saved healthcare payers a per-traveler average of $14 (9-day trip) to $372 (30-day trip). For travelers, consultations resulted in a range of net cost of $20 (9-day trip) to a net savings of $32 (30-day trip). Differences were mostly driven by risk of malaria in the destination country.
Conclusions. Our model suggests that healthcare payers save money for short- and longer-term trips, and that travelers save money for longer trips when travelers adhere to malaria recommendations and prophylactic regimens in West Africa. This is a potential incentive to healthcare payers to offer consistent pretravel preventive care to travelers. This financial benefit complements the medical benefit of reducing the risk of malaria.
C1 [Adachi, Kenji; Coleman, Margaret S.; Khan, Nomana; Jentes, Emily S.; Sotir, Mark J.; Brunette, Gary] Ctr Dis Control & Prevent, Div Global Migrat & Quarantine, Atlanta, GA 30333 USA.
[Arguin, Paul] Ctr Dis Control & Prevent, Div Parasit Dis & Malaria, Atlanta, GA 30333 USA.
[Rao, Sowmya R.] Univ Massachusetts Med Sch, Dept Quantitat Hlth Sci, Worcester, MA USA.
[Rao, Sowmya R.] Bedford VA Med Ctr, Ctr Hlth Qual Outcomes & Econ Res, Bedford, MA USA.
[LaRocque, Regina C.; Ryan, Edward T.] Massachusetts Gen Hosp, Div Infect Dis, Boston, MA 02114 USA.
[LaRocque, Regina C.; Ryan, Edward T.] Harvard Univ, Sch Med, Dept Med, Boston, MA USA.
[Meltzer, Martin I.] Ctr Dis Control & Prevent, Div Preparedness & Emerging Infect, Atlanta, GA 30333 USA.
RP Coleman, MS (reprint author), Ctr Dis Control & Prevent, Div Global Migrat & Quarantine, Natl Ctr Emerging & Zoonot Infect Dis, MS E-03,1600 Clifton Rd, Atlanta, GA 30333 USA.
EM mcoleman@cdc.gov
FU CDC [U19CI000514, U01CK000175]
FX This work was supported by the CDC (Cooperative Agreements U19CI000514
and U01CK000175).
NR 27
TC 2
Z9 2
U1 0
U2 4
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1058-4838
EI 1537-6591
J9 CLIN INFECT DIS
JI Clin. Infect. Dis.
PD JAN 1
PY 2014
VL 58
IS 1
BP 11
EP 21
DI 10.1093/cid/cit570
PG 11
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 280QC
UT WOS:000329044800009
PM 24014735
ER
PT J
AU Ly, KN
Xing, J
Klevens, RM
Jiles, RB
Holmberg, SD
AF Ly, Kathleen N.
Xing, Jian
Klevens, R. Monina
Jiles, Ruth B.
Holmberg, Scott D.
TI Causes of Death and Characteristics of Decedents With Viral Hepatitis,
United States, 2010
SO CLINICAL INFECTIOUS DISEASES
LA English
DT Article
DE viral hepatitis; mortality; death certificates; causes of death
ID CHRONIC LIVER-DISEASE; C VIRUS-INFECTION; SUSTAINED VIROLOGICAL
RESPONSE; ALL-CAUSE MORTALITY; HEPATOCELLULAR-CARCINOMA; COHORT; CARE;
VACCINATION; POPULATION; PREVALENCE
AB Background. Previous research indicates that the mortality burden from viral hepatitis is growing, particularly among middle-aged persons. To monitor progress toward prevention goals, it is important to continue to document characteristics and comortalities of these deaths. This study sought to examine demographic characteristics and the most frequent causes of death among decedents with a viral hepatitis-related death.
Methods. A cross-sectional study was performed on approximately 2.4 million death records from 2010. We calculated mortality rates for decedents with and without hepatitis A, B, and C virus (HAV, HBV, and HCV) and relative risks for the most frequently cited conditions in decedents with and without HBV and HCV.
Results. In 2010, there were 18 473 (0.7%) deaths with HAV, HBV, and HCV listed among causes of death, disproportionately in those aged 45-64 years. Among the 10 frequent causes of death, decedents listing HBV or HCV died, on average, 22-23 years earlier than decedents not listing these infections. HBV- and HCV-infected decedents aged 45-64 years had an increased risk of having the following conditions reported than decedents without these infections: cancer of liver and intrahepatic bile duct; fibrosis, cirrhosis, and other liver diseases; alcohol-related liver disease; gastrointestinal hemorrhage; human immunodeficiency infection; acute and unspecified renal failure; and septicemia (HCV only).
Conclusions. Decedents with other causes of death that include HBV or HCV died 22-23 years earlier than decedents not listing these infections. These data suggest and support the need for prevention, early identification, and treatment of HBV and HCV.
C1 [Ly, Kathleen N.; Xing, Jian; Klevens, R. Monina; Jiles, Ruth B.; Holmberg, Scott D.] Ctr Dis Control & Prevent, Div Viral Hepatitis, Atlanta, GA 30333 USA.
RP Ly, KN (reprint author), Ctr Dis Control & Prevent, Div Viral Hepatitis, 1600 Clifton Rd NE,Mailstop G-37, Atlanta, GA 30333 USA.
EM kathleenly@cdc.gov
FU US Department of Energy; CDC
FX Kathleen Ly was supported in part by an appointment to the Research
Participation Program at the CDC administered by the Oak Ridge Institute
for Science and Education through an interagency agreement between the
US Department of Energy and the CDC.
NR 37
TC 27
Z9 27
U1 0
U2 3
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1058-4838
EI 1537-6591
J9 CLIN INFECT DIS
JI Clin. Infect. Dis.
PD JAN 1
PY 2014
VL 58
IS 1
BP 40
EP 49
DI 10.1093/cid/cit642
PG 10
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 280QC
UT WOS:000329044800013
PM 24065331
ER
PT J
AU Ahmed, F
Lindley, MC
Allred, N
Weinbaum, CM
Grohskopf, L
AF Ahmed, Faruque
Lindley, Megan C.
Allred, Norma
Weinbaum, Cindy M.
Grohskopf, Lisa
TI Effect of Influenza Vaccination of Healthcare Personnel on Morbidity and
Mortality Among Patients: Systematic Review and Grading of Evidence
SO CLINICAL INFECTIOUS DISEASES
LA English
DT Review
DE decision making; evidence-based medicine; health personnel; influenza
vaccines; quality of healthcare
ID LONG-TERM-CARE; RESPIRATORY SYNCYTIAL VIRUS; RANDOMIZED
CONTROLLED-TRIAL; CASE DEFINITIONS; ELDERLY-PEOPLE; UNITED-STATES; HOME
STAFF; WORKERS; DISEASE; RECOMMENDATIONS
AB Background. Influenza vaccination of healthcare personnel (HCP) is recommended in >40 countries. However, there is controversy surrounding the evidence that HCP vaccination reduces morbidity and mortality among patients. Key factors for developing evidence-based recommendations include quality of evidence, balance of benefits and harms, and values and preferences.
Methods. We conducted a systematic review of randomized trials, cohort studies, and case-control studies published through June 2012 to evaluate the effect of HCP influenza vaccination on mortality, hospitalization, and influenza cases in patients of healthcare facilities. We pooled trial results using meta-analysis and assessed evidence quality using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.
Results. We identified 4 cluster randomized trials and 4 observational studies conducted in long-term care or hospital settings. Pooled risk ratios across trials for all-cause mortality and influenza-like illness were 0.71 (95% confidence interval [CI], .59-.85) and 0.58 (95% CI, .46-.73), respectively; pooled estimates for all-cause hospitalization and laboratory-confirmed influenza were not statistically significant. The cohort and case-control studies indicated significant protective associations for influenza-like illness and laboratory-confirmed influenza. No studies reported harms to patients. Using GRADE, the quality of the evidence for the effect of HCP vaccination on mortality and influenza cases in patients was moderate and low, respectively. The evidence quality for the effect of HCP vaccination on patient hospitalization was low. The overall evidence quality was moderate.
Conclusions. The quality of evidence is higher for mortality than for other outcomes. HCP influenza vaccination can enhance patient safety.
C1 [Ahmed, Faruque; Lindley, Megan C.; Allred, Norma] Ctr Dis Control & Prevent, Immunizat Serv Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
[Weinbaum, Cindy M.] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA.
[Grohskopf, Lisa] Ctr Dis Control & Prevent, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
RP Ahmed, F (reprint author), Ctr Dis Control & Prevent, Immunizat Serv Div, Natl Ctr Immunizat & Resp Dis, 1600 Clifton Rd NE,MS A-19, Atlanta, GA 30333 USA.
EM fahmed@cdc.gov
NR 40
TC 61
Z9 61
U1 1
U2 15
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1058-4838
EI 1537-6591
J9 CLIN INFECT DIS
JI Clin. Infect. Dis.
PD JAN 1
PY 2014
VL 58
IS 1
BP 50
EP 57
DI 10.1093/cid/cit580
PG 8
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 280QC
UT WOS:000329044800014
PM 24046301
ER
PT J
AU Mathison, BA
Pritt, BS
AF Mathison, Blaine A.
Pritt, Bobbi S.
TI Laboratory Identification of Arthropod Ectoparasites
SO CLINICAL MICROBIOLOGY REVIEWS
LA English
DT Review
ID RICKETTSIA-FELIS; URINARY MYIASIS; LYME-DISEASE; DIPTERA CALLIPHORIDAE;
MEGASELIA-SCALARIS; INTESTINAL MYIASIS; SERICATA DIPTERA;
ERISTALIS-TENAX; UNITED-STATES; TICKS ACARI
AB The collection, handling, identification, and reporting of ectoparasitic arthropods in clinical and reference diagnostic laboratories are discussed inthisreview. Included are data on ticks, mites, lice, fleas, myiasis-causing flies, and bed bugs. The public health importance of these organisms is briefly discussed. The focus is on the morphological identification and proper handling and reporting of cases involving arthropod ectoparasites, particularly those encountered in the United States. Other arthropods and other organisms not of public health concern, but routinely submitted to laboratories for identification, are also briefly discussed.
C1 [Mathison, Blaine A.] Ctr Dis Control & Prevent, Ctr Global Hlth, Div Parasit Dis & Malaria, Atlanta, GA 30333 USA.
[Pritt, Bobbi S.] Mayo Clin, Div Clin Microbiol, Rochester, MN USA.
RP Mathison, BA (reprint author), Ctr Dis Control & Prevent, Ctr Global Hlth, Div Parasit Dis & Malaria, Atlanta, GA 30333 USA.
EM gqa4@cdc.gov
OI Pritt, Bobbi/0000-0003-0261-1326
NR 139
TC 6
Z9 6
U1 1
U2 19
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0893-8512
EI 1098-6618
J9 CLIN MICROBIOL REV
JI Clin. Microbiol. Rev.
PD JAN
PY 2014
VL 27
IS 1
BP 48
EP 67
DI 10.1128/CMR.00008-13
PG 20
WC Microbiology
SC Microbiology
GA 284NC
UT WOS:000329324800003
PM 24396136
ER
PT J
AU Parola, P
Paddock, CD
Socolovschi, C
Labruna, MB
Mediannikov, O
Kernif, T
Abdad, MY
Stenos, J
Bitam, I
Fournier, PE
Raoult, D
AF Parola, Philippe
Paddock, Christopher D.
Socolovschi, Cristina
Labruna, Marcelo B.
Mediannikov, Oleg
Kernif, Tahar
Abdad, Mohammad Yazid
Stenos, John
Bitam, Idir
Fournier, Pierre-Edouard
Raoult, Didier
TI Update on Tick-Borne Rickettsioses around the World: a Geographic
Approach (vol 26, pg 657, 2013)
SO CLINICAL MICROBIOLOGY REVIEWS
LA English
DT Correction
C1 [Parola, Philippe] Aix Marseille Univ, Unite Rech Malad Infect & Trop Emergentes, UM63,Fac Med, CNRS 7278,IRD 198,WHO Collaborat Ctr Rickettslose, Marseille, France.
Ctr Dis Control & Prevent, Atlanta, GA USA.
Univ Sao Paulo, Fac Med Vet & Zootecnia, Dept Med Vet Prevent & Saude Anim, Sao Paulo, Brazil.
Inst Pasteur, Serv Ecol Syst Vectoriels, Algiers, Algeria.
Murdoch Univ, Australian Rickettsial Reference Lab, Div Vet & Biomed Sci, Barwon Hlth, Geelong, Vic, Australia.
Univ Boumerdes, Boumerdes, Algeria.
RP Parola, P (reprint author), Aix Marseille Univ, Unite Rech Malad Infect & Trop Emergentes, UM63,Fac Med, CNRS 7278,IRD 198,WHO Collaborat Ctr Rickettslose, Marseille, France.
RI Mediannikov, Oleg/H-4018-2015
OI Mediannikov, Oleg/0000-0001-6039-2008
NR 1
TC 3
Z9 3
U1 0
U2 10
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0893-8512
EI 1098-6618
J9 CLIN MICROBIOL REV
JI Clin. Microbiol. Rev.
PD JAN
PY 2014
VL 27
IS 1
BP 166
EP 166
DI 10.1128/CMR.00104-13
PG 1
WC Microbiology
SC Microbiology
GA 284NC
UT WOS:000329324800008
ER
PT J
AU Li, YX
Yin, ZD
Shao, ZJ
Li, MS
Liang, XF
Sandhu, HS
Hadler, SC
Li, JH
Sun, YQ
Li, J
Zou, WJ
Lin, M
Zuo, SY
Mayer, LW
Novak, RT
Zhu, BQ
Xu, L
Luo, HM
AF Li, Yixing
Yin, Zundong
Shao, Zhujun
Li, Manshi
Liang, Xiaofeng
Sandhu, Hardeep S.
Hadler, Stephen C.
Li, Junhong
Sun, Yinqi
Li, Jing
Zou, Wenjing
Lin, Mei
Zuo, Shuyan
Mayer, Leonard W.
Novak, Ryan T.
Zhu, Bingqing
Xu, Li
Luo, Huiming
CA Acute Meningitis Encephalitis
TI Population-based Surveillance for Bacterial Meningitis in China,
September 2006-December 2009
SO EMERGING INFECTIOUS DISEASES
LA English
DT Article
ID INFLUENZAE TYPE-B; REAL-TIME PCR; HAEMOPHILUS-INFLUENZAE;
STREPTOCOCCUS-PNEUMONIAE; NEISSERIA-MENINGITIDIS; CHILDREN;
EPIDEMIOLOGY; ENCEPHALITIS; BANGLADESH; DISEASES
AB During September 2006 December 2009, we conducted active population and sentinel laboratory based surveillance for bacterial meningitis pathogens, including Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae type b, in 4 China prefectures. We identified 7,876 acute meningitis and encephalitis syndrome cases, including 6,388 among prefecture residents. A total of 833 resident cases from sentinel hospitals met the World Health Organization case definition for probable bacterial meningitis; 339 of these cases were among children <5 years of age. Laboratory testing confirmed bacterial meningitis in 74 of 3,391 tested cases. The estimated annual incidence (per 100,000 population) of probable bacterial meningitis ranged from 1.84 to 2.93 for the entire population and from 6.95 to 22.30 for children <5 years old. Active surveillance with laboratory confirmation has provided a population-based estimate of the number of probable bacterial meningitis cases in China, but more complete laboratory testing is needed to better define the epidemiology of the disease in this country.
C1 [Li, Yixing; Yin, Zundong; Liang, Xiaofeng; Li, Junhong; Luo, Huiming] Chinese Ctr Dis Control & Prevent, Beijing 100050, Peoples R China.
[Shao, Zhujun] Natl Inst Communicable Dis Control & Prevent, Beijing, Peoples R China.
[Li, Manshi] Shandong Prov Ctr Dis Control & Prevent, Jinan, Peoples R China.
[Sandhu, Hardeep S.; Hadler, Stephen C.; Mayer, Leonard W.; Novak, Ryan T.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Sun, Yinqi; Li, Jing] Hebei Prov Ctr Dis Control & Prevent, Shijiazhuang, Peoples R China.
[Zou, Wenjing] Hubei Prov Ctr Dis Control & Prevent, Wuhan, Peoples R China.
[Lin, Mei] Guangxi Zhuang Autonomous Reg Ctr Dis Control & P, Nanning, Peoples R China.
[Zuo, Shuyan] World Hlth Org China Off, Beijing, Peoples R China.
[Zhu, Bingqing; Xu, Li] State Key Lab Infect Dis Prevent & Control, Beijing, Peoples R China.
RP Luo, HM (reprint author), Chinese Ctr Dis Control & Prevent, Natl Immunizat Programme, 27 Nanwei Rd, Beijing 100050, Peoples R China.
EM hmluo@vip.sina.com
FU US Centers for Disease Control and Prevention's Global Disease Detection
and Response Initiative
FX Financial support was provided by the Acute Meningitis-Encephalitis
Syndrome Surveillance project of US Centers for Disease Control and
Prevention's Global Disease Detection and Response Initiative.
NR 25
TC 9
Z9 11
U1 0
U2 6
PU CENTERS DISEASE CONTROL
PI ATLANTA
PA 1600 CLIFTON RD, ATLANTA, GA 30333 USA
SN 1080-6040
EI 1080-6059
J9 EMERG INFECT DIS
JI Emerg. Infect. Dis
PD JAN
PY 2014
VL 20
IS 1
BP 61
EP 69
DI 10.3201/eid2001.120375
PG 9
WC Immunology; Infectious Diseases
SC Immunology; Infectious Diseases
GA 283UI
UT WOS:000329272100009
PM 24377388
ER
PT J
AU Marini, RP
Cassiday, PK
Venezia, J
Shen, Z
Buckley, EM
Peters, Y
Taylor, N
Dewhirst, FE
Tondella, ML
Fox, JG
AF Marini, Robert P.
Cassiday, Pamela K.
Venezia, Jaime
Shen, Zeli
Buckley, Ellen M.
Peters, Yaicha
Taylor, Nancy
Dewhirst, Floyd E.
Tondella, Maria L.
Fox, James G.
TI Corynebacterium ulcerans in Ferrets
SO EMERGING INFECTIOUS DISEASES
LA English
DT Letter
ID DIPHTHERIAE; MACAQUES; CAT
C1 [Marini, Robert P.; Venezia, Jaime; Shen, Zeli; Buckley, Ellen M.; Peters, Yaicha; Taylor, Nancy; Fox, James G.] MIT, Cambridge, MA 02139 USA.
[Cassiday, Pamela K.; Tondella, Maria L.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Dewhirst, Floyd E.] Forsyth Inst, Cambridge, MA USA.
[Dewhirst, Floyd E.] Harvard Univ, Sch Dent Med, Boston, MA 02115 USA.
RP Fox, JG (reprint author), MIT, Div Comparat Med, Bldg 16-825C,77 Massachusetts Ave, Cambridge, MA 02139 USA.
EM jgfox@mit.edu
FU NIEHS NIH HHS [P30 ES002109]; NIH HHS [T32 OD010978]
NR 10
TC 7
Z9 7
U1 1
U2 1
PU CENTERS DISEASE CONTROL
PI ATLANTA
PA 1600 CLIFTON RD, ATLANTA, GA 30333 USA
SN 1080-6040
EI 1080-6059
J9 EMERG INFECT DIS
JI Emerg. Infect. Dis
PD JAN
PY 2014
VL 20
IS 1
BP 159
EP 161
DI 10.3201/eid2001.130675
PG 3
WC Immunology; Infectious Diseases
SC Immunology; Infectious Diseases
GA 283UI
UT WOS:000329272100032
PM 24377676
ER
PT J
AU Doi, Y
O'Hara, JA
Lando, JF
Querry, AM
Townsend, BM
Pasculle, AW
Muto, CA
AF Doi, Yohei
O'Hara, Jessica A.
Lando, James F.
Querry, Ashley M.
Townsend, Bethany M.
Pasculle, Anthony W.
Muto, Carlene A.
TI Co-Production of NDM-1 and OXA-232 by Klebsiella pneumoniae
SO EMERGING INFECTIOUS DISEASES
LA English
DT Letter
ID METALLO-BETA-LACTAMASE; UNITED-STATES; ENTEROBACTERIACEAE
C1 [Doi, Yohei; O'Hara, Jessica A.; Querry, Ashley M.; Townsend, Bethany M.; Pasculle, Anthony W.; Muto, Carlene A.] Univ Pittsburgh, Sch Med, Pittsburgh, PA 15261 USA.
[Lando, James F.] Ctr Dis Control & Prevent, Assigned Allegheny Cty Hlth Dept, Pittsburgh, PA USA.
RP Doi, Y (reprint author), Univ Pittsburgh, Sch Med, Div Infect Dis, Scaife Hall S829,3550 Terrace St, Pittsburgh, PA 15261 USA.
EM yod4@pitt.edu
NR 10
TC 19
Z9 19
U1 0
U2 2
PU CENTERS DISEASE CONTROL
PI ATLANTA
PA 1600 CLIFTON RD, ATLANTA, GA 30333 USA
SN 1080-6040
EI 1080-6059
J9 EMERG INFECT DIS
JI Emerg. Infect. Dis
PD JAN
PY 2014
VL 20
IS 1
BP 163
EP 165
DI 10.3201/eid2001.130904
PG 3
WC Immunology; Infectious Diseases
SC Immunology; Infectious Diseases
GA 283UI
UT WOS:000329272100034
PM 24377764
ER
PT J
AU Imanishi, M
Anderson, TC
Routh, J
Brown, C
Conidi, G
Glenn, L
Reddy, V
Waechter, H
Malavet, M
Nyaku, M
Bohm, S
Bidol, S
Arends, K
Saupe, A
Higa, J
Nguyen, TA
Pringle, J
Behravesh, CB
Bosch, S
AF Imanishi, Maho
Anderson, Tara C.
Routh, Janell
Brown, Catherine
Conidi, Giuseppe
Glenn, Lynda
Reddy, Vasudha
Waechter, HaeNa
Malavet, Michelle
Nyaku, Mawuli
Bohm, Susan
Bidol, Sally
Arends, Katherine
Saupe, Amy
Higa, Jeffrey
Thai-An Nguyen
Pringle, Jeshua
Behravesh, Casey Barton
Bosch, Stacey
TI Salmonellosis and Meat Purchased at Live-Bird and Animal-Slaughter
Markets, United States, 2007-2012
SO EMERGING INFECTIOUS DISEASES
LA English
DT Letter
ID AVIAN INFLUENZA
C1 [Imanishi, Maho; Anderson, Tara C.; Routh, Janell; Nyaku, Mawuli; Thai-An Nguyen; Pringle, Jeshua; Behravesh, Casey Barton; Bosch, Stacey] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
[Brown, Catherine; Conidi, Giuseppe; Glenn, Lynda] Massachusetts Dept Publ Hlth, Boston, MA USA.
[Reddy, Vasudha; Waechter, HaeNa] New York City Dept Hlth & Mental Hyg, New York, NY USA.
[Malavet, Michelle] New Jersey State Dept Hlth, Trenton, NJ 08625 USA.
[Nyaku, Mawuli; Bohm, Susan; Bidol, Sally; Arends, Katherine] Michigan Dept Community Hlth, Lansing, MI USA.
[Saupe, Amy] Minnesota Dept Hlth, St Paul, MN USA.
[Higa, Jeffrey] Calif Dept Publ Hlth, Gardena, CA USA.
RP Bosch, S (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd NE,Mailstop A38, Atlanta, GA 30333 USA.
EM gii5@cdc.gov
NR 7
TC 5
Z9 5
U1 0
U2 8
PU CENTERS DISEASE CONTROL
PI ATLANTA
PA 1600 CLIFTON RD, ATLANTA, GA 30333 USA
SN 1080-6040
EI 1080-6059
J9 EMERG INFECT DIS
JI Emerg. Infect. Dis
PD JAN
PY 2014
VL 20
IS 1
BP 167
EP 169
DI 10.3201/eid2001.131179
PG 3
WC Immunology; Infectious Diseases
SC Immunology; Infectious Diseases
GA 283UI
UT WOS:000329272100036
PM 24377875
ER
PT J
AU Cantonwine, DE
Cordero, JF
Rivera-Gonzalez, LO
Del Toro, LVA
Ferguson, KK
Mukherjee, B
Calafat, AM
Crespo, N
Jimenez-Velez, B
Padilla, IY
Alshawabkeh, AN
Meeker, JD
AF Cantonwine, David E.
Cordero, Jose F.
Rivera-Gonzalez, Luis O.
Del Toro, Liza V. Anzalota
Ferguson, Kelly K.
Mukherjee, Bhramar
Calafat, Antonia M.
Crespo, Noe
Jimenez-Velez, Braulio
Padilla, Ingrid Y.
Alshawabkeh, Akram N.
Meeker, John D.
TI Urinary phthalate metabolite concentrations among pregnant women in
Northern Puerto Rico: Distribution, temporal variability, and predictors
SO ENVIRONMENT INTERNATIONAL
LA English
DT Article
DE Endocrine disruptor; Phthalates; Environment; Epidemiology; Exposure;
Pregnancy
ID CARE PRODUCT USE; CONSUMER PRODUCTS; BIRTH OUTCOMES; BISPHENOL-A;
EXPOSURE; ESTERS; MEN; POPULATION; MONOESTERS; CHEMICALS
AB Background: Phthalate contamination exists in the North Coast karst aquifer system in Puerto Rico. In light of potential health impacts associated with phthalate exposure, targeted action for elimination of exposure sources may be warranted, especially for sensitive populations such as pregnant women. However, information on exposure to phthalates from a variety of sources in Puerto Rico is lacking. The objective of this study was to determine concentrations and predictors of urinary phthalate biomarkers measured at multiple times during pregnancy among women living in the Northern karst area of Puerto Rico.
Methods: We recruited 139 pregnant women in Northern Puerto Rico and collected urine samples and questionnaire data at three separate visits (18 +/- 2 weeks, 22 +/- 2 weeks, and 26 +/- 2 weeks of gestation). Urine samples were analyzed for eleven phthalate metabolites: mono-2-ethylhexyl phthalate (MEHP), mono-2-ethyl-5-hydroxyhexyl phthalate, mono-2-ethyl-5-oxohexyl phthalate, mono-2-ethyl-5-carboxypentyl phthalate, mono-ethyl phthalate (MEP), mono-n-butyl phthalate, mono-benzyl phthalate, mono-isobutyl phthalate, mono-3-carboxypropyl phthalate (MCPP), mono carboxyisononyl phthalate (MCNP), and mono carboxyisooctyl phthalate (MCOP).
Results: Detectable concentrations of phthalate metabolites among pregnant women living in Puerto Rico was prevalent, and metabolite concentrations tended to be higher than or similar to those measured in women of reproductive age from the general US population. Intraclass correlation coefficients ranged from very weak (MCNP; 0.05) to moderate (MEP; 0.44) reproducibility among all phthalate metabolites. We observed significant or suggestive positive associations between urinary phthalate metabolite concentrations and water usage/storage habits (MEP, MCNP, MCOP), use of personal care products (MEP), and consumption of certain food items (MCPP, MCNP, and MCOP).
Conclusions: To our knowledge this is the first study to report concentrations, temporal variability, and predictors of phthalate biomarkers among pregnant women in Puerto Rico. Preliminary results suggest several potentially important exposure sources to phthalates in this population and future analysis from this ongoing prospective cohort will help to inform targeted approaches to reduce exposure. (C) 2013 Elsevier Ltd. All rights reserved.
C1 [Cantonwine, David E.] Brigham & Womens Hosp, Dept Obstet & Gynecol, Boston, MA 02115 USA.
[Cordero, Jose F.; Del Toro, Liza V. Anzalota; Crespo, Noe; Jimenez-Velez, Braulio] Univ Puerto Rico, Grad Sch Publ Hlth, San Juan, PR 00936 USA.
[Rivera-Gonzalez, Luis O.; Ferguson, Kelly K.; Meeker, John D.] Univ Michigan, Sch Publ Hlth, Dept Environm Hlth Sci, Ann Arbor, MI 48109 USA.
[Mukherjee, Bhramar] Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA.
[Calafat, Antonia M.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Padilla, Ingrid Y.] Univ Puerto Rico, Dept Civil Engn & Surveying, Mayaguez, PR USA.
[Alshawabkeh, Akram N.] Northeastern Univ, Coll Engn, Boston, MA 02115 USA.
RP Cantonwine, DE (reprint author), Brigham & Womens Hosp, Dept Obstet & Gynecol, MFM Div, Room 304 CWN,75 Francis St, Boston, MA 02115 USA.
EM dcantonwine@partners.org
OI Meeker, John/0000-0001-8357-5085; Ferguson, Kelly/0000-0001-8467-3250
FU National Institute of Environmental Health Sciences (NIEHS)
[P42ES017198, P30ES017885]
FX The project described was supported by P42ES017198 and P30ES017885 from
the National Institute of Environmental Health Sciences (NIEHS). The
content is solely the responsibility of the authors and does not
necessarily represent the official views of the National Institute of
Environmental Health Sciences, the National Institutes of Health, or the
Centers for Disease Control and Prevention. The authors declare no
competing financial interests. We gratefully acknowledge Manori Silva,
Ella Samandar, Jim Preau, and Tao Jia for technical assistance in
measuring the urinary concentrations of the phthalate metabolites.
NR 54
TC 39
Z9 39
U1 7
U2 47
PU PERGAMON-ELSEVIER SCIENCE LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
SN 0160-4120
EI 1873-6750
J9 ENVIRON INT
JI Environ. Int.
PD JAN
PY 2014
VL 62
BP 1
EP 11
DI 10.1016/j.envint.2013.09.014
PG 11
WC Environmental Sciences
SC Environmental Sciences & Ecology
GA 280BF
UT WOS:000329003000001
PM 24161445
ER
PT J
AU Grosse, SD
Boulet, SL
Grant, AM
Hulihan, MM
Faughnan, ME
AF Grosse, Scott D.
Boulet, Sheree L.
Grant, Althea M.
Hulihan, Mary M.
Faughnan, Marie E.
TI The use of US health insurance data for surveillance of rare disorders:
hereditary hemorrhagic telangiectasia
SO GENETICS IN MEDICINE
LA English
DT Article
DE administrative data; epidemiology; Osler-Weber-Rendu disease; prevalence
ID ARTERIOVENOUS-MALFORMATION; MOLECULAR DIAGNOSIS; POPULATION;
EXPENDITURES; MORTALITY; CARE
AB Purpose: To assess the utility of US health insurance data for surveillance of hereditary hemorrhagic telangiectasia, an autosomal-dominant blood vasculature disorder with an estimated prevalence of 1.5-2.0 per 10,000 persons worldwide.
Methods: We used 2005-2010 MarketScan Research Databases to identify individuals with employer-sponsored health insurance and International Classification of Disease, 9th Revision, Clinical Modification codes of 448.0 present in either one inpatient claim or two outpatient claims 30 days apart to define hereditary hemorrhagic telangiectasia. We examined frequencies of International Classification of Disease, 9th Revision, Clinical Modification codes for conditions that are complications of hereditary hemorrhagic telangiectasia among individuals with hereditary hemorrhagic telangiectasia and the general population to identify combinations of codes associated with hereditary hemorrhagic telangiectasia.
Results: Excluding observations from one state, the average prevalence of hereditary hemorrhagic telangiectasia was 0.3 per 10,000 persons. The reported prevalence rose with age from similar to 0.1 per 10,000 at ages <30 years to 1.0-1.1 per 10,000 at ages 70 years and above. The condition codes that were most specific to presumed hereditary hemorrhagic telangiectasia were lung arteriovenous malformations and upper gastrointestinal angiodysplasia. Combinations of those codes and codes for brain arteriovenous malformation and epistaxis were highly predictive of reporting of hereditary hemorrhagic telangiectasia, with 20-57% of enrollees with those codes also meeting the study definition for hereditary hemorrhagic telangiectasia.
Conclusion: Hereditary hemorrhagic telangiectasia is underrecognized in US administrative data. Administrative health data can be used to identify individuals with combinations of signs that are suggestive of hereditary hemorrhagic telangiectasia. Studies are needed to test the hypothesis that referral for evaluation of individuals with administrative records suggestive of undiagnosed hereditary hemorrhagic telangiectasia could lead to diagnosis and access to life-saving treatments for both them and affected family members.
C1 [Grosse, Scott D.; Grant, Althea M.; Hulihan, Mary M.] Ctr Dis Control & Prevent, Div Blood Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USA.
[Boulet, Sheree L.] Ctr Dis Control & Prevent, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA.
[Faughnan, Marie E.] Univ Toronto, St Michaels Hosp, Dept Med, Toronto HHT Ctr,Div Respirol, Toronto, ON M5B 1W8, Canada.
[Faughnan, Marie E.] Univ Toronto, St Michaels Hosp, Li Ka Shing Knowledge Inst, Toronto, ON, Canada.
[Faughnan, Marie E.] HHT Fdn Int, Monkton, MD USA.
RP Grosse, SD (reprint author), Ctr Dis Control & Prevent, Div Blood Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USA.
EM sgrosse@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 25
TC 12
Z9 12
U1 0
U2 0
PU NATURE PUBLISHING GROUP
PI NEW YORK
PA 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA
SN 1098-3600
EI 1530-0366
J9 GENET MED
JI Genet. Med.
PD JAN
PY 2014
VL 16
IS 1
BP 33
EP 39
DI 10.1038/gim.2013.66
PG 7
WC Genetics & Heredity
SC Genetics & Heredity
GA 284GO
UT WOS:000329304300005
PM 23703685
ER
PT J
AU Scheuner, MT
Hamilton, AB
Peredo, J
Sale, TJ
Austin, C
Gilman, SC
Bowen, MS
Goldzweig, CL
Lee, M
Mittman, BS
Yano, EM
AF Scheuner, Maren T.
Hamilton, Alison B.
Peredo, Jane
Sale, Taylor J.
Austin, Colletta
Gilman, Stuart C.
Bowen, M. Scott
Goldzweig, Caroline Lubick
Lee, Martin
Mittman, Brian S.
Yano, Elizabeth M.
TI A cancer genetics toolkit improves access to genetic services through
documentation and use of the family history by primary-care clinicians
SO GENETICS IN MEDICINE
LA English
DT Article
DE family history; hereditary cancer; referral
ID BRCA2 MUTATION CARRIERS; CONTINUING MEDICAL-EDUCATION; WOMENS
HEALTH-CARE; BREAST-CANCER; COLORECTAL-CANCER; LYNCH-SYNDROME; GENOMIC
MEDICINE; RISK-ASSESSMENT; OVARIAN-CANCER; DELIVERY
AB Purpose: We developed, implemented, and evaluated a multicomponent cancer genetics toolkit designed to improve recognition and appropriate referral of individuals at risk for hereditary cancer syndromes.
Methods: We evaluated toolkit implementation in the women's clinics at a large Veterans Administration medical center using mixed methods, including pre-post semistructured interviews, clinician surveys, and chart reviews, and during implementation, monthly tracking of genetic consultation requests and use of a reminder in the electronic health record. We randomly sampled 10% of progress notes 6 months before (n = 139) and 18 months during implementation (n = 677).
Results: The toolkit increased cancer family history documentation by almost 10% (26.6% pre- and 36.3% postimplementation). The reminder was a key component of the toolkit; when used, it was associated with a twofold increase in cancer family history documentation (odds ratio = 2.09; 95% confidence interval: 1.39-3.15), and the history was more complete. Patients whose clinicians completed the reminder were twice as likely to be referred for genetic consultation (4.1-9.6%, P < 0.0001).
Conclusion: A multicomponent approach to the systematic collection and use of family history by primary-care clinicians increased access to genetic services.
C1 [Scheuner, Maren T.; Hamilton, Alison B.; Peredo, Jane; Sale, Taylor J.; Austin, Colletta; Goldzweig, Caroline Lubick; Lee, Martin; Mittman, Brian S.; Yano, Elizabeth M.] VA Greater Los Angeles Healthcare Syst, Los Angeles, CA 90073 USA.
[Scheuner, Maren T.; Goldzweig, Caroline Lubick] Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Los Angeles, CA 90095 USA.
[Hamilton, Alison B.] Univ Calif Los Angeles, David Geffen Sch Med, Dept Psychiat & Biobehav Sci, Los Angeles, CA 90095 USA.
[Gilman, Stuart C.] Vet Hlth Adm, Off Acad Affiliat, Washington, DC USA.
[Bowen, M. Scott] Ctr Dis Control & Prevent, Off Publ Hlth Genom, Atlanta, GA USA.
[Lee, Martin; Yano, Elizabeth M.] Univ Calif Los Angeles, Fielding Sch Publ Hlth, Los Angeles, CA USA.
RP Scheuner, MT (reprint author), VA Greater Los Angeles Healthcare Syst, Los Angeles, CA 90073 USA.
EM maren.scheuner@va.gov
OI Mittman, Brian/0000-0003-3589-9178
FU Centers for Disease Control and Prevention [1U38GD000047]
FX This publication was supported by Cooperative Agreement No. 1U38GD000047
from the Centers for Disease Control and Prevention. Its contents are
solely the responsibility of the authors and do not necessarily
represent the official views of the Centers for Disease Control and
Prevention. We thank Muin Khoury for his review of the manuscript (he
received no compensation), Lisa V. Rubenstein for her input to the study
design and review of implementation activities, Shannon Rhodes for data
management and preliminary analyses, and Austin Jones for his
contributions to data entry and quality assurance. Rubenstein, Rhodes,
and Jones provided these services in their respective roles as employees
at the VA Greater Los Angeles Healthcare System.
NR 38
TC 11
Z9 11
U1 0
U2 8
PU NATURE PUBLISHING GROUP
PI NEW YORK
PA 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA
SN 1098-3600
EI 1530-0366
J9 GENET MED
JI Genet. Med.
PD JAN
PY 2014
VL 16
IS 1
BP 60
EP 69
DI 10.1038/gim.2013.75
PG 10
WC Genetics & Heredity
SC Genetics & Heredity
GA 284GO
UT WOS:000329304300009
PM 23765051
ER
PT J
AU Grewal, P
Kamili, S
Motamed, D
AF Grewal, Priya
Kamili, Saleem
Motamed, David
TI Chronic Hepatitis E in an Immunocompetent Patient: A Case Report
SO HEPATOLOGY
LA English
DT Article
ID E VIRUS-INFECTION
C1 [Grewal, Priya; Motamed, David] Mt Sinai Med Ctr, Recanati Miller Transplantat Inst, New York, NY 10029 USA.
[Kamili, Saleem] Ctr Dis Control & Prevent, Div Viral Hepatitis, Atlanta, GA USA.
RP Grewal, P (reprint author), Mt Sinai Med Ctr, Div Liver Dis, Recanati Miller Transplantat Inst, 1425 Madison Ave,Suite 3-61,Box 1104, New York, NY 10029 USA.
EM Priya.grewal@mountsinai.org
NR 8
TC 17
Z9 20
U1 0
U2 3
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0270-9139
EI 1527-3350
J9 HEPATOLOGY
JI Hepatology
PD JAN
PY 2014
VL 59
IS 1
BP 347
EP 348
DI 10.1002/hep.26636
PG 2
WC Gastroenterology & Hepatology
SC Gastroenterology & Hepatology
GA 276GZ
UT WOS:000328738400035
PM 23913727
ER
PT J
AU Banach, DB
Francois, J
Blash, S
Patel, G
Jenkins, SG
LaBombardi, V
Kreiswirth, BN
Srinivasan, A
Calfee, DP
AF Banach, David B.
Francois, Jeannette
Blash, Stephanie
Patel, Gopi
Jenkins, Stephen G.
LaBombardi, Vincent
Kreiswirth, Barry N.
Srinivasan, Arjun
Calfee, David P.
TI Active Surveillance for Carbapenem-Resistant Enterobacteriaceae Using
Stool Specimens Submitted for Testing for Clostridium difficile
SO INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
LA English
DT Article
ID KLEBSIELLA-PNEUMONIAE; ACQUISITION
AB Active surveillance to identify asymptomatic carriers of carbapenem-resistant Enterobacteriaceae (CRE) is a recommended strategy for CRE control in healthcare facilities. Active surveillance using stool specimens tested for Clostridium difficile is a relatively low-cost strategy to detect CRE carriers. Further evaluation of this and other risk factor--based active surveillance strategies is warranted.
C1 [Banach, David B.; Blash, Stephanie; Patel, Gopi; LaBombardi, Vincent] Mt Sinai Sch Med, New York, NY USA.
[Francois, Jeannette] NewYork Presbyterian Hosp, New York, NY USA.
[Jenkins, Stephen G.; Calfee, David P.] Weill Cornell Med Coll, New York, NY 10065 USA.
[Kreiswirth, Barry N.] Univ Med & Dent New Jersey, Publ Hlth Res Inst, Int Ctr Publ Hlth, Newark, NJ 07103 USA.
[Srinivasan, Arjun] Ctr Dis Control & Prevent, Atlanta, GA USA.
RP Calfee, DP (reprint author), Weill Cornell Med Coll, 525 East 68th St,Box 265, New York, NY 10065 USA.
EM dpc9003@med.cornell.edu
FU Association of American Medical Colleges; Centers for Disease Control
and Prevention [MM-1085-09/09]; National Institutes of Health
[1R01AI090155]
FX This study was funded by the Association of American Medical Colleges
and the Centers for Disease Control and Prevention (cooperative
agreement MM-1085-09/09 to D.P.C.). This study was also supported by a
grant (to B.N.K.) from the National Institutes of Health (1R01AI090155).
NR 10
TC 5
Z9 5
U1 0
U2 1
PU UNIV CHICAGO PRESS
PI CHICAGO
PA 1427 E 60TH ST, CHICAGO, IL 60637-2954 USA
SN 0899-823X
EI 1559-6834
J9 INFECT CONT HOSP EP
JI Infect. Control Hosp. Epidemiol.
PD JAN 1
PY 2014
VL 35
IS 1
BP 82
EP 84
DI 10.1086/674391
PG 3
WC Public, Environmental & Occupational Health; Infectious Diseases
SC Public, Environmental & Occupational Health; Infectious Diseases
GA 272KZ
UT WOS:000328460800014
PM 24334803
ER
PT J
AU Mendonca, K
Hauser, R
Calafat, AM
Arbuckle, TE
Duty, SM
AF Mendonca, K.
Hauser, R.
Calafat, A. M.
Arbuckle, T. E.
Duty, S. M.
TI Bisphenol A concentrations in maternal breast milk and infant urine
SO INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH
LA English
DT Article
DE Bisphenol A; Breast milk; Urine; Infant; Exposure
ID TANDEM MASS-SPECTROMETRY; HPLC-MS/MS METHOD; ENVIRONMENTAL PHENOLS;
EXPOSURE; CHILDREN; BIRTH; VARIABILITY; PREDICTORS; PREGNANCY; CHEMICALS
AB The present report describes the distribution of breast milk and urinary free and total bisphenol A (BPA) concentrations, from 27 postpartum women and their 31 infants, and explores the influence of age, sex, and nutritional source on infant BPA urinary concentration.
Both free (unconjugated) and total (free plus conjugated) BPA concentrations from women's breast milk samples and infants' urine samples were measured by online solid-phase extraction coupled to high-performance liquid chromatography-isotope dilution tandem mass spectrometry. Descriptive statistics and nonparametric tests of group comparisons were conducted.
Total BPA was detected in 93 % of urine samples in this healthy infant population aged 3-15 months who were without known environmental exposure to BPA [interquartile range (IQR) = 1.2-4.4 mu g/L)]. Similarly, 75 % of the mothers' breast milk samples had detectable concentrations of total BPA (IQR = 0.4-1.4 mu g/L). The magnitude and frequency of detection of free BPA in the children's urine and the mothers' breast milk were much lower than the total concentrations.
Total BPA was detected in 93 % of this healthy infant population aged 3-15 months who are without known environmental exposure to BPA. Neither free nor total BPA urinary concentrations differed significantly by infant's sex or by nutritional source (breast milk and/or formula) while age group was of borderline significance. There were no significant correlations between free or total BPA concentrations in mothers' breast milk and their infants' urine.
C1 [Mendonca, K.; Duty, S. M.] Simmons Coll, Nursing Programs, Sch Nursing & Hlth Sci, Boston, MA 02115 USA.
[Hauser, R.] Harvard Univ, Sch Publ Hlth, Dept Environm Hlth, Boston, MA 02115 USA.
[Calafat, A. M.] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Atlanta, GA 30341 USA.
[Arbuckle, T. E.] Hlth Canada, Populat Studies Div, Hlth Environm & Consumer Safety Branch, Ottawa, ON K1A 0K9, Canada.
RP Duty, SM (reprint author), Simmons Coll, Nursing Programs, Sch Nursing & Hlth Sci, 300 Fenway,Sci Bldg,Room 314, Boston, MA 02115 USA.
EM susan.duty@simmons.edu
FU Harvard School of Public Health-National Institute of Environmental
Health Sciences (HSPH-NIEHS) [P30ES000002]
FX Jennifer Ford RN, BSN (Harvard School of Public Health). Dr. Elizabeth
Hait, MD (Children's Hospital, Boston, MA). Xiaoyun Ye, Xiaoliu Zhou,
Tao Jia, and Amber Bishop (CDC) for the measurements of BPA. The
biospecimen analyses were funded under the Government of Canada's
Chemicals Management Plan. Kaitlin Mendonca was supported by training
grant Harvard School of Public Health-National Institute of
Environmental Health Sciences (HSPH-NIEHS) Pilot Grant #P30ES000002.
NR 43
TC 26
Z9 28
U1 3
U2 33
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0340-0131
EI 1432-1246
J9 INT ARCH OCC ENV HEA
JI Int. Arch. Occup. Environ. Health
PD JAN
PY 2014
VL 87
IS 1
BP 13
EP 20
DI 10.1007/s00420-012-0834-9
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 283GJ
UT WOS:000329233900002
PM 23212895
ER
PT J
AU Carson, PJ
Prince, HE
Biggerstaff, BJ
Lanciotti, R
Tobler, LH
Busch, M
AF Carson, Paul J.
Prince, Harry E.
Biggerstaff, Brad J.
Lanciotti, Robert
Tobler, Leslie H.
Busch, Michael
TI Characteristics of Antibody Responses in West Nile Virus-Seropositive
Blood Donors
SO JOURNAL OF CLINICAL MICROBIOLOGY
LA English
DT Article
ID INFECTION; RNA; PROTECTION; SEROLOGY; DISEASE
AB West Nile virus (WNV) is now endemic in the United States. Protection against infection is thought to be conferred in part by humoral immunity. An understanding of the durability and specificity of the humoral response is not well established. We studied the magnitude and specificity of antibody responses in 370 WNV-seropositive blood donors. We also recalled 18 donors who were infected in 2005 to compare their antibody responses at 6 months following infection versus at 5 years postinfection. There were no significant differences in IgG antibody levels based on age, sex, or recent infection (as evidenced by IgM positivity). Specific antibody responses by viral plaque reduction neutralization testing (PRNT) were seen in 51/54 subjects evaluated. All donors who were seropositive in 2005 remained seropositive at 5 years and maintained neutralizing antibodies. IgG levels at 5 years postinfection showed fairly minimal decreases compared with the paired levels at 6 months postinfection (mean of paired differences, -0.54 signal-to-cutoff ratio (S/CO) units [95% confidence interval {CI}, -0.86 to -0.21 S/CO units]) and only minimal decreases in PRNT titers. WNV induces a significant antibody response that remains present even 5 years after infection.
C1 [Carson, Paul J.] Univ N Dakota, Sch Med, Grand Forks, ND 58202 USA.
[Carson, Paul J.] Sanford Hlth, Fargo, ND USA.
[Prince, Harry E.] Focus Diagnost, Cypress, CA USA.
[Biggerstaff, Brad J.; Lanciotti, Robert] Ctr Dis Control & Prevent, Ft Collins, CO USA.
[Tobler, Leslie H.; Busch, Michael] Blood Syst Res Inst, San Francisco, CA USA.
RP Carson, PJ (reprint author), Univ N Dakota, Sch Med, Grand Forks, ND 58202 USA.
EM paul.carson@sanfordhealth.org
FU Centers for Disease Control and Prevention [R01-CI-000214]; National
Heart, Lung, and Blood Institute [RC2-HL-101632]
FX This work was funded in part by grants from the Centers for Disease
Control and Prevention (R01-CI-000214) and the National Heart, Lung, and
Blood Institute (RC2-HL-101632).
NR 19
TC 7
Z9 7
U1 0
U2 1
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0095-1137
EI 1098-660X
J9 J CLIN MICROBIOL
JI J. Clin. Microbiol.
PD JAN
PY 2014
VL 52
IS 1
BP 57
EP 60
DI 10.1128/JCM.01932-13
PG 4
WC Microbiology
SC Microbiology
GA 283CM
UT WOS:000329222400010
PM 24131687
ER
PT J
AU Lu, XY
Whitaker, B
Sakthivel, SKK
Kamili, S
Rose, LE
Lowe, L
Mohareb, E
Elassal, EM
Al-sanouri, T
Haddadin, A
Erdman, DD
AF Lu, Xiaoyan
Whitaker, Brett
Sakthivel, Senthil Kumar K.
Kamili, Shifaq
Rose, Laura E.
Lowe, Luis
Mohareb, Emad
Elassal, Emad M.
Al-sanouri, Tarek
Haddadin, Aktham
Erdman, Dean D.
TI Real-Time Reverse Transcription-PCR Assay Panel for Middle East
Respiratory Syndrome Coronavirus
SO JOURNAL OF CLINICAL MICROBIOLOGY
LA English
DT Article
ID SARS CORONAVIRUS; CLINICAL-FEATURES; INFECTION; PNEUMONIA; PLASMA
AB A new human coronavirus (CoV), subsequently named Middle East respiratory syndrome (MERS)-CoV, was first reported in Saudi Arabia in September 2012. In response, we developed two real-time reverse transcription-PCR (rRT-PCR) assays targeting the MERS-CoV nucleocapsid (N) gene and evaluated these assays as a panel with a previously published assay targeting the region upstream of the MERS-CoV envelope gene (upE) for the detection and confirmation of MERS-CoV infection. All assays detected <= 10 copies/reaction of quantified RNA transcripts, with a linear dynamic range of 8 log units and 1.3 x 10(-3) 50% tissue culture infective doses (TCID50)/ml of cultured MERS-CoV per reaction. All assays performed comparably with respiratory, serum, and stool specimens spiked with cultured virus. No false-positive amplifications were obtained with other human coronaviruses or common respiratory viral pathogens or with 336 diverse clinical specimens from non-MERS-CoV cases; specimens from two confirmed MERS-CoV cases were positive with all assay signatures. In June 2012, the U. S. Food and Drug Administration authorized emergency use of the rRT-PCR assay panel as an in vitro diagnostic test for MERS-CoV. A kit consisting of the three assay signatures and a positive control was assembled and distributed to public health laboratories in the United States and internationally to support MERS-CoV surveillance and public health responses.
C1 [Lu, Xiaoyan; Whitaker, Brett; Sakthivel, Senthil Kumar K.; Kamili, Shifaq; Erdman, Dean D.] Ctr Dis Control & Prevent, Div Viral Dis, Atlanta, GA 30333 USA.
[Rose, Laura E.; Lowe, Luis] Ctr Dis Control & Prevent, Div Preparedness & Emerging Infect, Atlanta, GA USA.
[Mohareb, Emad; Elassal, Emad M.] US Naval Med Res Unit 3, Cairo, Egypt.
[Al-sanouri, Tarek; Haddadin, Aktham] Minist Hlth, Cent Publ Hlth Lab, Amman, Jordan.
RP Erdman, DD (reprint author), Ctr Dis Control & Prevent, Div Viral Dis, Atlanta, GA 30333 USA.
EM dde1@cdc.gov
NR 15
TC 37
Z9 42
U1 1
U2 8
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0095-1137
EI 1098-660X
J9 J CLIN MICROBIOL
JI J. Clin. Microbiol.
PD JAN
PY 2014
VL 52
IS 1
BP 67
EP 75
DI 10.1128/JCM.02533-13
PG 9
WC Microbiology
SC Microbiology
GA 283CM
UT WOS:000329222400012
PM 24153118
ER
PT J
AU Vega, E
Barclay, L
Gregoricus, N
Shirley, SH
Lee, D
Vinje, J
AF Vega, Everardo
Barclay, Leslie
Gregoricus, Nicole
Shirley, S. Hannah
Lee, David
Vinje, Jan
TI Genotypic and Epidemiologic Trends of Norovirus Outbreaks in the United
States, 2009 to 2013
SO JOURNAL OF CLINICAL MICROBIOLOGY
LA English
DT Article
ID GII.4 SYDNEY NOROVIRUS; GASTROENTERITIS; STRAIN; SURVEILLANCE;
EMERGENCE; SYSTEM; RECOMBINATION; TRANSMISSION; INFECTIONS; EVOLUTION
AB Noroviruses are the leading cause of epidemic acute gastroenteritis in the United States. From September 2009 through August 2013, 3,960 norovirus outbreaks were reported to CaliciNet. Of the 2,895 outbreaks with a known transmission route, person-to-person and food-borne transmissions were reported for 2,425 (83.7%) and 465 (16.1%) of the outbreaks, respectively. A total of 2,475 outbreaks (62.5%) occurred in long-term care facilities (LTCF), 389 (9.8%) in restaurants, and 227 (5.7%) in schools. A total of 435 outbreaks (11%) were typed as genogroup I (GI) and 3,525 (89%) as GII noroviruses. GII.4 viruses caused 2,853 (72%) of all outbreaks, of which 94% typed as either GII.4 New Orleans or GII.4 Sydney. In addition, three non-GII.4 viruses, i.e., GII.12, GII.1, and GI.6, caused 528 (13%) of all outbreaks. Several non-GII.4 genotypes (GI.3, GI.6, GI.7, GII.3, GII.6, and GII.12) were significantly more associated with food-borne transmission (odds ratio, 1.9 to 7.1; P < 0.05). Patients in LTCF and people >= 65 years of age were at higher risk for GII.4 infections than those in other settings and with other genotypes (P < 0.05). Phylogeographic analysis identified three major dispersions from two geographic locations that were responsible for the GI.6 outbreaks from 2011 to 2013. In conclusion, our data demonstrate the cyclic emergence of new (non-GII.4) norovirus strains, and several genotypes are more often associated with food-borne outbreaks. These surveillance data can be used to improve viral food-borne surveillance and to help guide studies to develop and evaluate targeted prevention methods such as norovirus vaccines, antivirals, and environmental decontamination methods.
C1 [Vega, Everardo; Barclay, Leslie; Gregoricus, Nicole; Shirley, S. Hannah; Lee, David; Vinje, Jan] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
[Shirley, S. Hannah; Lee, David] Atlanta Res & Educ Fdn, Atlanta, GA USA.
RP Vega, E (reprint author), Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
EM evega@cdc.gov; jvinje@cdc.gov
FU intramural food safety program at the Centers for Disease Control and
Prevention; Agriculture and Food Research Initiative Competitive from
the U. S. Department of Agriculture, National Institute of Food and
Agriculture [2011-68003-30395]
FX This study was supported by the intramural food safety program at the
Centers for Disease Control and Prevention and in part by Agriculture
and Food Research Initiative Competitive Grant 2011-68003-30395 from the
U. S. Department of Agriculture, National Institute of Food and
Agriculture.
NR 44
TC 87
Z9 90
U1 4
U2 29
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0095-1137
EI 1098-660X
J9 J CLIN MICROBIOL
JI J. Clin. Microbiol.
PD JAN
PY 2014
VL 52
IS 1
BP 147
EP 155
DI 10.1128/JCM.02680-13
PG 9
WC Microbiology
SC Microbiology
GA 283CM
UT WOS:000329222400023
PM 24172151
ER
PT J
AU Kozak-Muiznieks, NA
Lucas, CE
Brown, E
Pondo, T
Taylor, TH
Frace, M
Miskowski, D
Winchell, JM
AF Kozak-Muiznieks, Natalia A.
Lucas, Claressa E.
Brown, Ellen
Pondo, Tracy
Taylor, Thomas H., Jr.
Frace, Michael
Miskowski, Diane
Winchell, Jonas M.
TI Prevalence of Sequence Types among Clinical and Environmental Isolates
of Legionella pneumophila Serogroup 1 in the United States from 1982 to
2012
SO JOURNAL OF CLINICAL MICROBIOLOGY
LA English
DT Article
ID MONOCLONAL-ANTIBODY SUBGROUPS; LEGIONNAIRES-DISEASE; DISCRIMINATORY
ABILITY; STRAINS; SCHEME; WATER; JAPAN; SURVEILLANCE; DIVERSITY;
OUTBREAK
AB Since the establishment of sequence-based typing as the gold standard for DNA-based typing of Legionella pneumophila, the Legionella laboratory at the Centers for Disease Control and Prevention (CDC) has conducted routine sequence-based typing (SBT) analysis of all incoming L. pneumophila serogroup 1 (Lp1) isolates to identify potential links between cases and to better understand genetic diversity and clonal expansion among L. pneumophila bacteria. Retrospective genotyping of Lp1 isolates from sporadic cases and Legionnaires' disease (LD) outbreaks deposited into the CDC reference collection since 1982 has been completed. For this study, we compared the distribution of sequence types (STs) among Lp1 isolates implicated in 26 outbreaks in the United States, 571 clinical isolates from sporadic cases of LD in the United States, and 149 environmental isolates with no known association with LD. The Lp1 isolates under study had been deposited into our collection between 1982 and 2012. We identified 17 outbreak-associated STs, 153 sporadic STs, and 49 environmental STs. We observed that Lp1 STs from outbreaks and sporadic cases are more similar to each other than either group is to environmental STs. The most frequent ST for both sporadic and environmental isolates was ST1, accounting for 25% and 49% of the total number of isolates, respectively. The STs shared by both outbreak-associated and sporadic Lp1 included ST1, ST35, ST36, ST37, and ST222. The STs most commonly found in sporadic and outbreak-associated Lp1 populations may have an increased ability to cause disease and thus may require special attention when detected.
C1 [Kozak-Muiznieks, Natalia A.; Lucas, Claressa E.; Brown, Ellen; Pondo, Tracy; Taylor, Thomas H., Jr.; Winchell, Jonas M.] Ctr Dis Control & Prevent, Div Bacterial Dis, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
[Frace, Michael] Ctr Dis Control & Prevent, Biotechnol Core Facil Branch, Div Sci Resources, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA USA.
[Miskowski, Diane] EMSL Analyt Inc, Cinnaminson, NJ USA.
RP Winchell, JM (reprint author), Ctr Dis Control & Prevent, Div Bacterial Dis, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
EM Jwinchell@cdc.gov
FU CDC NCEH/NCZVED Safe Water Foundation
FX This work was supported by funding from the CDC NCEH/NCZVED Safe Water
Foundation.
NR 39
TC 15
Z9 15
U1 0
U2 5
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0095-1137
EI 1098-660X
J9 J CLIN MICROBIOL
JI J. Clin. Microbiol.
PD JAN
PY 2014
VL 52
IS 1
BP 201
EP 211
DI 10.1128/JCM.01973-13
PG 11
WC Microbiology
SC Microbiology
GA 283CM
UT WOS:000329222400030
PM 24197883
ER
PT J
AU Donskey, CJ
Sunkesula, VCK
Jencson, AL
Stone, ND
Gould, CV
McDonald, LC
Samore, M
Mayer, J
Pacheco, S
Sambol, S
Petrella, L
Terry, D
Gerding, DN
AF Donskey, Curtis J.
Sunkesula, Venkata C. K.
Jencson, Annette L.
Stone, Nimalie D.
Gould, Carolyn V.
McDonald, L. Clifford
Samore, Matthew
Mayer, Jeanmarie
Pacheco, Susan
Sambol, Susan
Petrella, Laurica
Terry, Deborah
Gerding, Dale N.
TI Utility of a Commercial PCR Assay and a Clinical Prediction Rule for
Detection of Toxigenic Clostridium difficile in Asymptomatic Carriers
SO JOURNAL OF CLINICAL MICROBIOLOGY
LA English
DT Article
ID TERM-CARE FACILITY; HOSPITALIZED-PATIENTS; INFECTION; COLONIZATION;
RESIDENTS; TRANSMISSION
AB A commercial PCR assay of perirectal swab specimens detected 17 (68%) of 25 asymptomatic carriers of toxigenic Clostridium difficile, including 93% with skin and/or environmental contamination. A clinical prediction rule, followed by PCR screening, could be used to identify carriers at high risk of C. difficile shedding.
C1 [Donskey, Curtis J.; Sunkesula, Venkata C. K.; Jencson, Annette L.] Cleveland Vet Affairs Med Ctr, Geriatr Res Educ & Clin Ctr, Cleveland, OH 44106 USA.
[Stone, Nimalie D.; Gould, Carolyn V.; McDonald, L. Clifford] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Samore, Matthew; Mayer, Jeanmarie] Univ Utah, Salt Lake City, UT USA.
[Pacheco, Susan; Sambol, Susan; Petrella, Laurica; Terry, Deborah; Gerding, Dale N.] Hines Vet Affairs Hosp, Chicago, IL USA.
RP Donskey, CJ (reprint author), Cleveland Vet Affairs Med Ctr, Geriatr Res Educ & Clin Ctr, Cleveland, OH 44106 USA.
EM curtisd123@yahoo.com; vs123@outlook.com
FU Centers for Disease Control and Prevention; Department of Veterans
Affairs; ViroPharma; Pfizer; Cubist; GOJO
FX This study was supported by the Centers for Disease Control and
Prevention and by the Department of Veterans Affairs.; C. J. Donskey is
a consultant for GOJO and 3M and has received research grants from
ViroPharma, Pfizer, and Cubist. D. N. G. holds patents for the treatment
and prevention of CDI licensed to ViroPharma; is a consultant for Sanofi
Pasteur, Merck, ViroPharma, GSK, Roche, Novartis, Cubist, Cangene, and
Actelion; and holds a research grant from GOJO.
NR 14
TC 10
Z9 10
U1 2
U2 5
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0095-1137
EI 1098-660X
J9 J CLIN MICROBIOL
JI J. Clin. Microbiol.
PD JAN
PY 2014
VL 52
IS 1
BP 315
EP 318
DI 10.1128/JCM.01852-13
PG 4
WC Microbiology
SC Microbiology
GA 283CM
UT WOS:000329222400048
PM 24153132
ER
PT J
AU Glass, RI
Parashar, U
Patel, M
Gentsch, J
Jiang, BM
AF Glass, Roger I.
Parashar, Umesh
Patel, Manish
Gentsch, Jon
Jiang, Baoming
TI Rotavirus vaccines: Successes and challenges
SO JOURNAL OF INFECTION
LA English
DT Article
DE Rotavirus; Vaccines; Childhood diarrhea
ID CHILDHOOD DIARRHEA; UNITED-STATES; ACUTE GASTROENTERITIS; VACCINATION
PROGRAMS; GLOBAL SEASONALITY; YOUNG-CHILDREN; INFECTION; INFANTS;
EFFICACY; ANTIBODY
AB Since 2006, the availability of two new rotavirus vaccines has raised enthusiasm to consider the eventual control and elimination of severe rotavirus diarrhea through the global use of vaccines. Rotavirus remains the most severe cause of acute diarrhea in children worldwide responsible for several hundred thousands of deaths in low income countries and up to half of hospital admissions for diarrhea around the world. The new vaccines have been recommended by WHO for all infants and in more than 47 countries, their introduction into routine childhood immunization programs has led to a remarkable decline in hospital admissions and even deaths within 3 years of introduction. Challenges remain with issues of vaccine finance globally and the problem that these live oral vaccines perform less well in low income settings where they are needed most. Ongoing research that will accompany vaccine introduction might help address these issues of efficacy and new vaccines and novel financing schemes may both help make these vaccines universally available and affordable in the decade. Published by Elsevier Ltd on behalf of The British Infection Association.
C1 [Glass, Roger I.] NIH, Fogarty Int Ctr, Bethesda, MD 20892 USA.
[Parashar, Umesh; Patel, Manish; Gentsch, Jon; Jiang, Baoming] Ctr Dis Control & Prevent, Viral Gastroenteritis Team, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
RP Glass, RI (reprint author), NIH, Fogarty Int Ctr, 31 Ctr Dr,Mailstop 2220, Bethesda, MD 20892 USA.
EM glassr@mail.nih.gov; uap2@CDC.GOV; aul3@CDC.GOV; jrg4@CDC.GOV;
bxj4@CDC.GOV
FU CDC; U.S. Government
FX All of this work has been funded through the CDC and the U.S.
Government.
NR 59
TC 28
Z9 30
U1 2
U2 9
PU W B SAUNDERS CO LTD
PI LONDON
PA 32 JAMESTOWN RD, LONDON NW1 7BY, ENGLAND
SN 0163-4453
EI 1532-2742
J9 J INFECTION
JI J. Infect.
PD JAN
PY 2014
VL 68
SU 1
BP S9
EP S18
DI 10.1016/j.jinf.2013.09.010
PG 10
WC Infectious Diseases
SC Infectious Diseases
GA 283CN
UT WOS:000329222500003
PM 24156947
ER
PT J
AU Wolter, N
Cohen, C
Tempia, S
Madhi, SA
Venter, M
Moyes, J
Walaza, S
Kgokong, BM
Groome, M
du Plessis, M
Pretorius, M
Dawood, H
Kahn, K
Variava, E
Klugman, KP
von Gottberg, A
AF Wolter, Nicole
Cohen, Cheryl
Tempia, Stefano
Madhi, Shabir A.
Venter, Marietjie
Moyes, Jocelyn
Walaza, Sibongile
Kgokong, Babatyi Malope
Groome, Michelle
du Plessis, Mignon
Pretorius, Marthi
Dawood, Halima
Kahn, Kathleen
Variava, Ebrahim
Klugman, Keith P.
von Gottberg, Anne
TI HIV and Influenza Virus Infections Are Associated With Increased Blood
Pneumococcal Load: A Prospective, Hospital-Based Observational Study in
South Africa, 2009-2011
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article
DE Streptococcus pneurnoniae; pneumococcal pneumonia; bacterial load; HIV;
influenza
ID POLYMERASE-CHAIN-REACTION; COMMUNITY-ACQUIRED PNEUMONIA; GENOMIC
BACTERIAL LOAD; STREPTOCOCCUS-PNEUMONIAE; CONJUGATE VACCINE;
HEALTHY-CHILDREN; MOUSE MODEL; DISEASE; SAMPLES; IMPACT
AB Background. Increased pneumococcal loads are associated with severe outcomes. We determined the prevalence of pneumococcal DNA in blood specimens from patients hospitalized with acute lower respiratory tract infection and identified factors associated with invasive pneumococcal pneumonia, bacterial loads, and death.
Methods. A total of 8523 patients were enrolled as part of prospective hospital-based surveillance. Blood was collected for quantitative pneumococcal (tytA) detection, and nasopharyngeal specimens were collected for detection of influenza virus and other respiratory viruses by real-time polymerase chain reaction.
Results. Of 6396 cases (75%) with /ytA results, 422 (7%) were positive for pneumococcal DNA. The prevalences of human immunodeficiency virus (HIV) and influenza virus were 51% (2965/5855) and 8% (485/6358), respectively. On multivariable analysis, HIV infection (adjusted odds ratio [aOR], 2.4; 95% confidence interval [CI], 1.6-3.6), influenza virus coinfection (aOR, 1.4; 95% CI, 1.2-2.1), oxygen therapy during admission (a0R, 1.6; 95% CI, 1.1-2.3) and in-hospital death (aOR, 2.1; 95% CI, 1.1-4.0) were significantly associated with increased pneumococcal load. Among /ytA-positive patients, after adjustment for length of hospitalization, duration of symptoms, and oxygen therapy during admission, pneumococcal loads >= 10,000 DNA copies/mi. (a0R, 3.6; 95% CI, 1.8-7.2) were associated with increased risk of death.
Conclusions. HIV and influenza virus infections were associated with elevated pneumococcal loads, which, in turn, were associated with increased risk of death.
C1 [Wolter, Nicole; Cohen, Cheryl; Tempia, Stefano; Madhi, Shabir A.; Venter, Marietjie; Moyes, Jocelyn; Walaza, Sibongile; Kgokong, Babatyi Malope; du Plessis, Mignon; Pretorius, Marthi; Klugman, Keith P.; von Gottberg, Anne] Natl Inst Communicable Dis, Ctr Resp Dis & Meningitis, Natl Hlth Lab Serv, ZA-2131 Johannesburg, Gauteng, South Africa.
[Wolter, Nicole; Cohen, Cheryl; du Plessis, Mignon; von Gottberg, Anne] Fac Hlth Sci, Johannesburg, South Africa.
[Kahn, Kathleen] Univ Witwatersrand, Fac Hlth Sci, MRC, Wits Rural Publ Hlth & Hlth Transit Res Unit Agin, ZA-2050 Johannesburg, South Africa.
[Madhi, Shabir A.; Groome, Michelle] Natl Res Fdn Vaccine Preventable Dis, Dept Sci & Technol, Johannesburg, South Africa.
[Venter, Marietjie] Univ Pretoria, Dept Med Virol, ZA-0001 Pretoria, South Africa.
[Dawood, Halima] Pietermaritzburg Metropolitan Hosp, Edendale Hosp, Pietermaritzburg, South Africa.
[Variava, Ebrahim] Klerksdorp Tshepong Hosp, Klerksdorp, South Africa.
[Tempia, Stefano] Ctr Dis Control & Prevent, Influenza Div, Atlanta, GA USA.
[Klugman, Keith P.] Emory Univ, Hubert Dept Global Hlth, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA.
[Klugman, Keith P.] Emory Univ, Sch Med, Div Infect Dis, Atlanta, GA USA.
[Kahn, Kathleen] Umea Univ, Ctr Global Hlth Res, Umea, Sweden.
[Kahn, Kathleen] INDEPTH Network, Accra, Ghana.
RP Wolter, N (reprint author), Natl Inst Communicable Dis, Ctr Resp Dis & Meningitis, Private Bag X4, ZA-2131 Johannesburg, Gauteng, South Africa.
EM nicolew@nicd.ac.za
RI Venter, Marietjie/P-9604-2016;
OI Venter, Marietjie/0000-0003-2696-824X; du Plessis,
Mignon/0000-0001-9186-0679
FU Pfizer South Africa [WS1167521]; Centers for Disease Control and
Prevention [5U51IP0001551]
FX This work was supported by Pfizer South Africa (Investigator initiated
research agreement WS1167521) and the Centers for Disease Control and
Prevention (cooperative agreement 5U51IP0001551).
NR 43
TC 9
Z9 9
U1 1
U2 3
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0022-1899
EI 1537-6613
J9 J INFECT DIS
JI J. Infect. Dis.
PD JAN 1
PY 2014
VL 209
IS 1
BP 56
EP 65
DI 10.1093/infdis/jit427
PG 10
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 282FY
UT WOS:000329157000010
PM 23922370
ER
PT J
AU Visser, SN
Danielson, ML
Bitsko, RH
Holbrook, JR
Kogan, MD
Ghandour, RM
Perou, R
Blumberg, SJ
AF Visser, Susanna N.
Danielson, Melissa L.
Bitsko, Rebecca H.
Holbrook, Joseph R.
Kogan, Michael D.
Ghandour, Reem M.
Perou, Ruth
Blumberg, Stephen J.
TI Trends in the Parent-Report of Health Care Provider-Diagnosed and
Medicated Attention-Deficit/Hyperactivity Disorder: United States,
2003-2011
SO JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
LA English
DT Article
DE attention-deficit/hyperactivity disorder (ADHD); epidemiology;
medication; prevalence; stimulants
ID DEFICIT HYPERACTIVITY DISORDER; SUPPLEMENT NCS-A; SUBSTANCE USE;
STIMULANT MEDICATION; MULTIMODAL TREATMENT; TREATMENT STRATEGIES;
MENTAL-DISORDERS; CHILDHOOD ADHD; US CHILDREN; FOLLOW-UP
AB Objective: Data from the 2003 and 2007 National Survey of Children's Health (NSCH) reflect the increasing prevalence of parent-reported attention-deficit/hyperactivity disorder (ADHD) diagnosis and treatment by health care providers. This report updates these prevalence estimates for 2011 and describes temporal trends. Method: Weighted analyses were conducted with 2011 NSCH data to estimate prevalence of parent-reported ADHD diagnosis, current ADHD, current medication treatment, ADHD severity, and mean age of diagnosis for U.S. children/adolescents aged 4 to 17 years and among demographic subgroups. A history of ADHD diagnosis (2003-2011), as well as current ADHD and medication treatment prevalence (2007-2011), were compared using prevalence ratios and 95% confidence intervals. Results: In 2011, 11% of children/adolescents aged 4 to 17 years had ever received an ADHD diagnosis (6.4 million children). Among those with a history of ADHD diagnosis, 83% were reported as currently having ADHD (8.8%); 69% of children with current ADHD were taking medication for ADHD (6.1%, 3.5 million children). A parent-reported history of ADHD increased by 42% from 2003 to 2011. Prevalence of a history of ADHD, current ADHD, medicated ADHD, and moderate/severe ADHD increased significantly from 2007 estimates. Prevalence of medicated ADHD increased by 28% from 2007 to 2011. Conclusions: Approximately 2 million more U.S. children/adolescents aged 4 to 17 years had been diagnosed with ADHD in 2011, compared to 2003. More than two-thirds of those with current ADHD were taking medication for treatment in 2011. This suggests an increasing burden of ADHD on the U.S. health care system. Efforts to further understand ADHD diagnostic and treatment patterns are warranted. J. Am. Acad. Child Adolesc. Psychiatry, 2014;53(1)34-46.
C1 [Visser, Susanna N.; Danielson, Melissa L.; Bitsko, Rebecca H.; Holbrook, Joseph R.; Perou, Ruth] Ctr Dis Control & Prevent CDC, Div Human Dev & Disabil, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30329 USA.
[Kogan, Michael D.; Ghandour, Reem M.] US Hlth Resources & Serv Adm, Off Epidemiol & Res, Maternal & Child Hlth Bur, Rockville, MD 20857 USA.
[Blumberg, Stephen J.] CDC, Div Hlth Interview Stat, Natl Ctr Hlth Stat, Atlanta, GA 30333 USA.
RP Visser, SN (reprint author), Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, E-88,1600 Clifton Rd, Atlanta, GA 30333 USA.
EM svisser@cdc.gov
OI Danielson, Melissa/0000-0001-9461-0341
FU Maternal and Child Health Bureau of the Health Resources and Services
Administration
FX The National Survey of Children's Health is a module of the Centers for
Disease Control and Prevention's State and Local Area Integrated
Telephone Survey and was sponsored by the Maternal and Child Health
Bureau of the Health Resources and Services Administration.
NR 56
TC 154
Z9 155
U1 2
U2 41
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0890-8567
EI 1527-5418
J9 J AM ACAD CHILD PSY
JI J. Am. Acad. Child Adolesc. Psychiatr.
PD JAN
PY 2014
VL 53
IS 1
BP 34
EP 46
DI 10.1016/j.jaac.2013.09.001
PG 13
WC Psychology, Developmental; Pediatrics; Psychiatry
SC Psychology; Pediatrics; Psychiatry
GA 280GG
UT WOS:000329016100006
PM 24342384
ER
PT J
AU Alymova, IV
Samarasinghe, A
Vogel, P
Green, AM
Weinlich, R
McCullers, JA
AF Alymova, Irina V.
Samarasinghe, Amali
Vogel, Peter
Green, Amanda M.
Weinlich, Ricardo
McCullers, Jonathan A.
TI A Novel Cytotoxic Sequence Contributes to Influenza A Viral Protein
PB1-F2 Pathogenicity and Predisposition to Secondary Bacterial Infection
SO JOURNAL OF VIROLOGY
LA English
DT Article
ID CELL-SPECIFIC PROTEIN; VIRUS PROTEIN; MITOCHONDRIAL-MEMBRANE; DIFFERENT
STRAINS; INTERFERON; EXPRESSION; PNEUMONIA
AB Enhancement of cell death is a distinguishing feature of H1N1 influenza virus A/Puerto Rico/8/34 protein PB1-F2. Comparing the sequences (amino acids [aa] 61 to 87 using PB1-F2 amino acid numbering) of the PB1-F2-derived C-terminal peptides from influenza A viruses inducing high or low levels of cell death, we identified a unique I68, L69, and V70 motif in A/Puerto Rico/8/34 PB1-F2 responsible for promotion of the peptide's cytotoxicity and permeabilization of the mitochondrial membrane. When administered to mice, a 27-mer PB1-F2-derived C-terminal peptide with this amino acid motif caused significantly greater weight loss and pulmonary inflammation than the peptide without it (due to I68T, L69Q, and V70G mutations). Similar to the wild-type peptide, A/Puerto Rico/8/34 elicited significantly higher levels of macrophages, neutrophils, and cytokines in the bronchoalveolar lavage fluid of mice than its mutant counterpart 7 days after infection. Additionally, infection of mice with A/Puerto Rico/8/34 significantly enhanced the levels of morphologically transformed epithelial and immune mononuclear cells recruited in the airways compared with the mutant virus. In the mouse bacterial superinfection model, both peptide and virus with the I68, L69, and V70 sequence accelerated development of pneumococcal pneumonia, as reflected by increased levels of viral and bacterial lung titers and by greater mortality. Here we provide evidence suggesting that the newly identified cytotoxic sequence I68, L69, and V70 of A/Puerto Rico/8/34 PB1-F2 contributes to the pathogenesis of both primary viral and secondary bacterial infections.
C1 [Alymova, Irina V.] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Influenza Div, Atlanta, GA 30333 USA.
[Alymova, Irina V.; Green, Amanda M.; McCullers, Jonathan A.] St Jude Childrens Res Hosp, Dept Infect Dis, Memphis, TN 38105 USA.
[Vogel, Peter] St Jude Childrens Res Hosp, Dept Pathol, Memphis, TN 38105 USA.
[Weinlich, Ricardo] St Jude Childrens Res Hosp, Dept Immunol, Memphis, TN 38105 USA.
[Samarasinghe, Amali; McCullers, Jonathan A.] Univ Tennessee, Ctr Hlth Sci, Dept Pediat, Memphis, TN 38163 USA.
RP Alymova, IV (reprint author), Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Influenza Div, Atlanta, GA 30333 USA.
EM ialymova@cdc.gov
RI Weinlich, Ricardo/S-7495-2016;
OI Samarasinghe, Amali/0000-0002-3104-2823
FU American Lebanese Syrian Associated Charities (ALSAC)
FX This work was supported by the American Lebanese Syrian Associated
Charities (ALSAC).
NR 34
TC 15
Z9 15
U1 0
U2 3
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0022-538X
EI 1098-5514
J9 J VIROL
JI J. Virol.
PD JAN
PY 2014
VL 88
IS 1
BP 503
EP 515
DI 10.1128/JVI.01373-13
PG 13
WC Virology
SC Virology
GA 282SW
UT WOS:000329194600046
PM 24173220
ER
PT J
AU Michael, SL
Wentzel, K
Elliott, MN
Dittus, PJ
Kanouse, DE
Wallander, JL
Pasch, KE
Franzini, L
Taylor, WC
Qureshi, T
Franklin, FA
Schuster, MA
AF Michael, Shannon L.
Wentzel, Kathryn
Elliott, Marc N.
Dittus, Patricia J.
Kanouse, David E.
Wallander, Jan L.
Pasch, Keryn E.
Franzini, Luisa
Taylor, Wendell C.
Qureshi, Tariq
Franklin, Frank A.
Schuster, Mark A.
TI Parental and Peer Factors Associated with Body Image Discrepancy among
Fifth-Grade Boys and Girls
SO JOURNAL OF YOUTH AND ADOLESCENCE
LA English
DT Article
DE Body image discrepancy; Peer factors; Parental factors; Self-worth;
Fifth graders
ID QUALITY-OF-LIFE; SELF-ESTEEM; ADOLESCENT GIRLS; MEDIA INFLUENCES;
PREADOLESCENT CHILDREN; 12-YEAR-OLD GIRLS; WEIGHT STATUS; RISK-FACTORS;
MASS INDEX; DISSATISFACTION
AB Many young adolescents are dissatisfied with their body due to a discrepancy between their ideal and actual body size, which can lead to weight cycling, eating disorders, depression, and obesity. The current study examined the associations of parental and peer factors with fifth-graders' body image discrepancy, physical self-worth as a mediator between parental and peer factors and body image discrepancy, and how these associations vary by child's sex. Body image discrepancy was defined as the difference between young adolescents' self-perceived body size and the size they believe a person their age should be. Data for this study came from Healthy Passages, which surveyed 5,147 fifth graders (51 % females; 34 % African American, 35 % Latino, 24 % White, and 6 % other) and their primary caregivers from the United States. Path analyses were conducted separately for boys and girls. The findings for boys suggest father nurturance and getting along with peers are related negatively to body image discrepancy; however, for girls, fear of negative evaluation by peers is related positively to body image discrepancy. For both boys and girls, getting along with peers and fear of negative evaluation by peers are related directly to physical self-worth. In addition, mother nurturance is related positively to physical self-worth for girls, and father nurturance is related positively to physical self-worth for boys. In turn, physical self-worth, for both boys and girls, is related negatively to body image discrepancy. The findings highlight the potential of parental and peer factors to reduce fifth graders' body image discrepancy.
C1 [Michael, Shannon L.; Qureshi, Tariq] Ctr Dis Control & Prevent, Atlanta, GA 30341 USA.
[Michael, Shannon L.; Wentzel, Kathryn] Univ Maryland, College Pk, MD 20742 USA.
[Elliott, Marc N.; Kanouse, David E.] RAND Corp, Santa Monica, CA 90407 USA.
[Dittus, Patricia J.] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
[Wallander, Jan L.] Univ Calif, Merced, CA 95343 USA.
[Pasch, Keryn E.] Univ Texas Austin, Austin, TX 78712 USA.
[Franzini, Luisa; Taylor, Wendell C.] Univ Texas Hlth Sci Ctr Houston, Houston, TX 77030 USA.
[Franklin, Frank A.] Univ Alabama Birmingham, Birmingham, AL 35294 USA.
[Schuster, Mark A.] Harvard Univ, Sch Med, Dept Pediat, Boston, MA 02115 USA.
[Schuster, Mark A.] Childrens Hosp, Dept Med, Div Gen Pediat, Boston, MA 02115 USA.
RP Michael, SL (reprint author), Ctr Dis Control & Prevent, 4770 Buford Highway NE,MS K-12, Atlanta, GA 30341 USA.
EM sot2@cdc.gov; wentzel@umd.edu; Marc_Elliott@rand.org; pdittus@cdc.gov;
kanouse@rand.org; jwallander@ucmerced.edu; kpasch@austin.utexas.edu;
luisa.franzini@uth.tmc.edu; Wendell.C.Taylor@uth.tmc.edu; tq@tariqq.com;
FFranklin@ms.soph.uab.edu; mark.schuster@childrens.harvard.edu
RI Johnson, Marilyn/E-7209-2011
FU Intramural CDC HHS [CC999999]
NR 62
TC 5
Z9 7
U1 2
U2 34
PU SPRINGER/PLENUM PUBLISHERS
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0047-2891
EI 1573-6601
J9 J YOUTH ADOLESCENCE
JI J. Youth Adolesc.
PD JAN
PY 2014
VL 43
IS 1
BP 15
EP 29
DI 10.1007/s10964-012-9899-8
PG 15
WC Psychology, Developmental
SC Psychology
GA 283JB
UT WOS:000329241200002
PM 23334988
ER
PT J
AU Almeida, J
Mulready-Ward, C
Bettegowda, VR
Ahluwalia, IB
AF Almeida, Joanna
Mulready-Ward, Candace
Bettegowda, Vani R.
Ahluwalia, Indu B.
TI Racial/Ethnic and Nativity Differences in Birth Outcomes Among Mothers
in New York City: The Role of Social Ties and Social Support
SO MATERNAL AND CHILD HEALTH JOURNAL
LA English
DT Article
DE Low birth weight; Preterm birth; Race/ethnicity; Immigrants; Social
ties; Social support
ID EPIDEMIOLOGIC PARADOX; PREGNANCY OUTCOMES; HEALTH BEHAVIORS;
UNITED-STATES; FOREIGN-BORN; PERINATAL HEALTH; MEXICAN DESCENT; WEIGHT;
WOMEN; ACCULTURATION
AB Immigrants have lower rates of low birth weight (LBW) and to some extent preterm birth (PTB), than their US-born counterparts. This pattern has been termed the 'immigrant health paradox'. Social ties and support are one proposed explanation for this phenomenon. We examined the contribution of social ties and social support to LBW and PTB by race/ethnicity and nativity among women in New York City (NYC). The NYC Pregnancy Risk Assessment Monitoring System survey (2004-2007) data, linked with the selected items from birth certificates, were used to examine LBW and PTB by race/ethnicity and nativity status and the role of social ties and social support to adverse birth outcomes using bivariate and multivariable analyses. SUDAAN software was used to adjust for complex survey design and sampling weights. US- and foreign-born Blacks had significantly increased odds of PTB [adjusted odds ratio (AOR) = 2.43, 95 % CI 1.56, 3.77 and AOR = 2.6, 95 % CI 1.66, 4.24, respectively] compared to US-born Whites. Odds of PTB among foreign-born Other Latinas, Island-born Puerto Ricans' and foreign-born Asians' were not significantly different from US-born Whites, while odds of PTB for foreign-born Whites were significantly lower (AOR = 0.47, 95 % CI 0.26, 0.84). US and foreign-born Blacks' odds of LBW were 2.5 fold that of US-born Whites. Fewer social ties were associated with 32-39 % lower odds of PTB. Lower social support was associated with decreased odds of LBW (AOR 0.69, 95 % CI 0.50, 0.96). We found stronger evidence of the immigrant health paradox across racial/ethnic groups for PTB than for LBW. Results also point to the importance of accurately assessing social ties and social support during pregnancy and to considering the potential downside of social ties.
C1 [Almeida, Joanna] Simmons Sch Social Work, Boston, MA USA.
[Mulready-Ward, Candace] Bur Maternal Infant & Reprod Hlth, NYC Dept Hlth & Mental Hyg, New York, NY USA.
[Bettegowda, Vani R.] March Dimes Fdn, Perinatal Data Ctr, White Plains, NY USA.
[Ahluwalia, Indu B.] Ctr Dis Control & Prevent, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA.
RP Almeida, J (reprint author), Simmons Sch Social Work, Boston, MA USA.
EM joanna.almeida@simmons.edu
NR 50
TC 4
Z9 4
U1 2
U2 9
PU SPRINGER/PLENUM PUBLISHERS
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1092-7875
EI 1573-6628
J9 MATERN CHILD HLTH J
JI Matern. Child Health J.
PD JAN
PY 2014
VL 18
IS 1
BP 90
EP 100
DI 10.1007/s10995-013-1238-5
PG 11
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 283MG
UT WOS:000329249600011
PM 23435918
ER
PT J
AU Smith, JJ
Robinson, RF
Khan, BA
Sosnoff, CS
Dillard, DA
AF Smith, Julia J.
Robinson, Renee F.
Khan, Burhan A.
Sosnoff, Connie S.
Dillard, Denise A.
TI Estimating Cotinine Associations and a Saliva Cotinine Level to Identify
Active Cigarette Smoking in Alaska Native Pregnant Women
SO MATERNAL AND CHILD HEALTH JOURNAL
LA English
DT Article
DE Maternal cigarette smoking; Pregnant women; Saliva cotinine; Alaska
native women
ID TANDEM MASS-SPECTROMETRY; SELF-REPORTED SMOKING; TOBACCO-SMOKE; SERUM
COTININE; UNITED-STATES; MATERNAL SMOKING; PASSIVE SMOKING; EXPOSURE;
NONSMOKERS; NICOTINE
AB Studies indicate nicotine metabolism varies by race and can change during pregnancy. Given high rates of tobacco use and limited studies among Alaska Native (AN) women, we estimated associations of saliva cotinine levels with cigarette use and second-hand smoke (SHS) exposure and estimated a saliva cotinine cutoff to distinguish smoking from non-smoking pregnant AN women. Using questionnaire data and saliva cotinine, we utilized multi-variable linear regression (n = 370) to estimate cotinine associations with tobacco use, SHS exposure, demographic, and pregnancy-related factors. Additionally, we estimated an optimal saliva cotinine cutoff for indication of active cigarette use in AN pregnant women using receiver operating characteristic (ROC) curve analysis (n = 377). Saliva cotinine significantly decreased with maternal age and significantly increased with cigarettes smoked per day, SHS exposure, and number of previous full term pregnancies. Using self-reported cigarette use in the past 7 days as indication of active smoking, the area under the ROC curve was 0.975 (95 % CI: 0.960-0.990). The point closest to 100 % specificity and sensitivity occurred with a cotinine concentration of 1.07 ng/mL, which corresponded to sensitivity of 94 % and specificity of 94 %. We recommend using a saliva cotinine cutoff of 1 ng/mL to distinguish active smoking in pregnant AN women. This cutoff is lower than used in other studies with pregnant women, most likely due to high prevalence of light or intermittent smoking in the AN population. Continued study of cotinine levels in diverse populations is needed.
C1 [Smith, Julia J.; Robinson, Renee F.; Khan, Burhan A.; Dillard, Denise A.] Southcent Fdn Res Dept, Anchorage, AK 99501 USA.
[Sosnoff, Connie S.] Ctr Dis Control & Prevent, Div Sci Lab, Atlanta, GA 30341 USA.
RP Smith, JJ (reprint author), Southcent Fdn Res Dept, 4501 Diplomacy Dr,Suite 200, Anchorage, AK 99501 USA.
EM jsmith@southcentralfoundation.com
NR 52
TC 2
Z9 2
U1 0
U2 4
PU SPRINGER/PLENUM PUBLISHERS
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1092-7875
EI 1573-6628
J9 MATERN CHILD HLTH J
JI Matern. Child Health J.
PD JAN
PY 2014
VL 18
IS 1
BP 120
EP 128
DI 10.1007/s10995-013-1241-x
PG 9
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 283MG
UT WOS:000329249600014
PM 23423858
ER
PT J
AU Klein, EG
Liu, ST
Conrey, EJ
AF Klein, Elizabeth G.
Liu, Sherry T.
Conrey, Elizabeth J.
TI Comprehensive Smoke-Free Policies: A Tool for Improving Preconception
Health?
SO MATERNAL AND CHILD HEALTH JOURNAL
LA English
DT Article
DE Smoking; Policy; Low-income; Women; WIC; Preconception health
ID UNITED-STATES; TOBACCO USE; PRENATAL SMOKING; PREGNANT SMOKERS;
SECONDHAND SMOKE; WOMEN; CESSATION; CARE; INDICATORS; TRENDS
AB Lower income women are at higher risk for preconception and prenatal smoking, are less likely to spontaneously quit smoking during pregnancy, and have higher prenatal relapse rates than women in higher income groups. Policies prohibiting tobacco smoking in public places are intended to reduce exposure to secondhand smoke; additionally, since these policies promote a smoke-free norm, there have been associations between smoke-free policies and reduced smoking prevalence. Given the public health burden of smoking, particularly among women who become pregnant, our objective was to assess the impact of smoke-free policies on the odds of preconception smoking among low-income women. We estimated the odds of preconception smoking among low-income women in Ohio between 2002 and 2009 using data from repeated cross-sectional samples of women participating in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC). A logistic spline regression was applied fitting a knot at the point of enforcement of the Ohio Smoke-free Workplace Act to evaluate whether this policy was associated with changes in the odds of smoking. After adjusting for individual- and environmental-level factors, the Ohio Smoke-free Workplace Act was associated with a small, but statistically significant reduction in the odds of preconception smoking in WIC participants. Comprehensive smoke-free policies prohibiting smoking in public places and workplaces may also be associated with reductions in smoking among low-income women. This type of policy or environmental change strategy may promote a tobacco-free norm and improve preconception health among a population at risk for smoking.
C1 [Klein, Elizabeth G.; Liu, Sherry T.] Ohio State Univ, Coll Publ Hlth, Div Hlth Behav & Hlth Promot, Columbus, OH 43210 USA.
[Conrey, Elizabeth J.] Ohio Dept Hlth, State Epidemiol Off, Columbus, OH 43266 USA.
[Conrey, Elizabeth J.] Ctr Dis Control & Prevent, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA.
RP Klein, EG (reprint author), Ohio State Univ, Coll Publ Hlth, Div Hlth Behav & Hlth Promot, Columbus, OH 43210 USA.
EM eklein@cph.osu.edu
RI Klein, Elizabeth/B-3195-2012
OI Klein, Elizabeth/0000-0002-6895-4682
NR 43
TC 2
Z9 2
U1 1
U2 8
PU SPRINGER/PLENUM PUBLISHERS
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1092-7875
EI 1573-6628
J9 MATERN CHILD HLTH J
JI Matern. Child Health J.
PD JAN
PY 2014
VL 18
IS 1
BP 146
EP 152
DI 10.1007/s10995-013-1247-4
PG 7
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 283MG
UT WOS:000329249600017
PM 23467844
ER
PT J
AU King, JP
Gazmararian, JA
Shapiro-Mendoza, CK
AF King, Jennifer P.
Gazmararian, Julie A.
Shapiro-Mendoza, Carrie K.
TI Disparities in Mortality Rates Among US Infants Born Late Preterm or
Early Term, 2003-2005
SO MATERNAL AND CHILD HEALTH JOURNAL
LA English
DT Article
DE Infant mortality; Preterm infants; Disparities; Vital statistics
ID UNITED-STATES; NEONATAL-MORTALITY; SINGLETON BIRTHS; GESTATIONAL-AGE;
MATERNAL AGE; RISK; TRENDS; RACE; PREGNANCY; OUTCOMES
AB The purpose of this study was to identify disparities in neonatal, post-neonatal, and overall infant mortality rates among infants born late preterm (34-36 weeks gestation) and early term (37-38 weeks gestation) by race/ethnicity, maternal age, and plurality. In analyses of 2003-2005 data from US period linked birth/infant death datasets, we compared infant mortality rates by race/ethnicity, maternal age, and plurality among infants born late preterm or early term and also determined the leading causes of death among these infants. Among infants born late preterm, infants born to American Indian/Alaskan Native, non-Hispanic black, or teenage mothers had the highest infant mortality rates per 1,000 live births (14.85, 9.90, and 11.88 respectively). Among infants born early term, corresponding mortality rates were 5.69, 4.49, and 4.82, respectively. Among infants born late preterm, singletons had a higher infant mortality rate than twins (8.59 vs. 5.62), whereas among infants born early term, the rate was higher among twins (3.67 vs. 3.15). Congenital malformations and sudden infant death syndrome were the leading causes of death among both late preterm and early term infants. Infant mortality rates among infants born late preterm or early term varied substantially by maternal race/ethnicity, maternal age, and plurality. Information about these disparities may help in the development of clinical practice and prevention strategies targeting infants at highest risk.
C1 [King, Jennifer P.; Gazmararian, Julie A.] Emory Univ, Rollins Sch Publ Hlth, Dept Epidemiol, Atlanta, GA 30322 USA.
[King, Jennifer P.] Marshfield Med Res Fdn, Epidemiol Res Ctr, Marshfield, WI 54449 USA.
[Shapiro-Mendoza, Carrie K.] Ctr Dis Control & Prevent, Maternal & Infant Hlth Branch, Div Reprod Hlth, Atlanta, GA 30341 USA.
RP King, JP (reprint author), Marshfield Med Res Fdn, Epidemiol Res Ctr, 1000N Oak Ave ML2, Marshfield, WI 54449 USA.
EM king.jennifer@marshfieldclinic.org; jagazma@emory.edu; ayn9@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 33
TC 4
Z9 5
U1 1
U2 11
PU SPRINGER/PLENUM PUBLISHERS
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1092-7875
EI 1573-6628
J9 MATERN CHILD HLTH J
JI Matern. Child Health J.
PD JAN
PY 2014
VL 18
IS 1
BP 233
EP 241
DI 10.1007/s10995-013-1259-0
PG 9
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 283MG
UT WOS:000329249600026
PM 23519825
ER
PT J
AU Kulcsar, M
Gilchrist, S
George, MG
AF Kulcsar, Michael
Gilchrist, Siobhan
George, Mary G.
TI Improving Stroke Outcomes in Rural Areas Through Telestroke Programs: An
Examination of Barriers, Facilitators, and State Policies
SO TELEMEDICINE AND E-HEALTH
LA English
DT Article
DE telemedicine; telestroke; rural; stroke
ID ACUTE ISCHEMIC-STROKE; AMERICAN-HEART-ASSOCIATION; UNITED-STATES;
PLASMINOGEN-ACTIVATOR; POOLED ANALYSIS; TELEMEDICINE; CARE; DELIVERY;
RECOMMENDATIONS; THROMBOLYSIS
AB Introduction:Every year in the United States more than 600,000 ischemic stroke patients do not receive proven, effective stroke treatment or may not be medically eligible to receive the one medication endorsed by the U.S. Food and Drug Administration for acute ischemic stroke. The lack of treatment is due partly to shortages of neurological experts in rural and underserved areas. Telestroke programs can improve stroke care for stroke patients in rural and underserved settings by using interactive telecommunication technology that connects centrally located neurological experts to rural healthcare facilities. Many states have enacted policies and practices that facilitate telestroke access.Materials and Methods:We reviewed statutes and regulations in all 50 states that affect the adoption of telemedicine programs and describe examples of state-implemented programs in two states with policies that encourage telestroke use.Results and Discussion:This review presents evidence of the value and effectiveness of telestroke programs, as well as an explanation of common barriers and facilitators of telestroke, including licensing and credentialing rules, reimbursement issues, and liability concerns. Most states have adopted policies that affect the adoption of telestroke programs. Georgia and South Carolina are examples of states implementing stroke policies using a telestroke model to treat stroke patients in rural areas.
C1 [Kulcsar, Michael] Fulton Cty Juvenile Court, Atlanta, GA USA.
[Gilchrist, Siobhan] Columbus Technol & Serv Inc, Chamblee, GA USA.
[George, Mary G.] Ctr Dis Control & Prevent CDC, Div Heart Dis & Stroke Prevent, Atlanta, GA 30341 USA.
RP George, MG (reprint author), Ctr Dis Control & Prevent CDC, Div Heart Dis & Stroke Prevent, 4770 Buford Hwy NE,MS F72, Atlanta, GA 30341 USA.
EM coq5@cdc.gov
NR 35
TC 2
Z9 2
U1 2
U2 8
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1530-5627
EI 1556-3669
J9 TELEMED E-HEALTH
JI Telemed. e-Health
PD JAN 1
PY 2014
VL 20
IS 1
BP 3
EP 10
DI 10.1089/tmj.2013.0048
PG 8
WC Health Care Sciences & Services
SC Health Care Sciences & Services
GA 282HV
UT WOS:000329162700002
PM 24286197
ER
PT J
AU Collard, JM
Wang, X
Mahamane, AE
Idi, I
Issaka, B
Ousseni, M
Mayer, LW
Nato, F
Moulia-Pelat, JP
AF Collard, Jean-Marc
Wang, Xin
Mahamane, Ali Elhaj
Idi, Issa
Issaka, Bassira
Ousseni, Moumouni
Mayer, Leonard W.
Nato, Farida
Moulia-Pelat, Jean-Paul
TI A five-year field assessment of rapid diagnostic tests for meningococcal
meningitis in Niger by using the combination of conventional and
real-time PCR assays as a gold standard
SO TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Article
DE Early detection; Meningitis; Neisseria meningitidis serogroups A and W;
Niger; Patient treatment; Rapid diagnostic tests
ID NEISSERIA-MENINGITIDIS; BACTERIAL-MENINGITIS; SEROGROUP-A;
IDENTIFICATION; AGREEMENT; AFRICA; W135
AB Meningococcocal meningitis represents an important cause of mortality and morbidity in sub-Saharan countries. Confirmatory bacteriological or molecular diagnosis is essential for patient management/treatment and meningitis surveillance, but many laboratory tests are expensive and rarely available for low-income countries. A rapid diagnostic test (RDT) represents a valuable alternative to improve case management and surveillance.
A dipstick RDT developed in early 2000s that detects Neisseria meningitidis serogroups A, C, W and Y but for which a new conjugated antibody (L4-8) for the detection of serogroup A replaced the original K15-2 was assessed in the field by trained staff from health centres and district hospitals in Niger. The results were compared to those obtained in the reference laboratory and the sensitivity and specificity of RDTs were determined using conventional and real-time PCR assays as a gold standard.
RDT results from field staff and the reference laboratory obtained for 2095 cerebrospinal fluid (CSF) specimens presented a strong concordance of 94 with Cohens coefficient of 0.88. The observed concordance between RDTs operated by staff from the reference laboratory vs combination of conventional and real-time PCR assays was 89 with Cohens coefficient of 0.76 indicating very good agreement. The theoretical overall sensitivity for RDT was 91.5 and the specificity 84.6.
RDT has proven to be relatively sensitive and specific for the detection of meningococcal serogroups A/C/Y/W. We confirmed that these RDTs can be reliably operated by trained but non-specialised staff in basic health facilities.
C1 [Collard, Jean-Marc; Mahamane, Ali Elhaj; Idi, Issa; Issaka, Bassira; Ousseni, Moumouni; Moulia-Pelat, Jean-Paul] Ctr Rech Med & Sanit CERMES, Niamey, Niger.
[Wang, Xin; Mayer, Leonard W.] Ctr Dis Control & Prevent, Div Bacterial Dis, Atlanta, GA USA.
[Nato, Farida] Inst Pasteur, Platform Recombinant Prot & Antibody Prod PT5, Paris, France.
RP Collard, JM (reprint author), Sci Inst Publ Hlth, Brussels, Belgium.
EM Jean-Marc.Collard@wiv-isp.be
FU French Ministry of Foreign Affairs [FSP] [2005-174]; Sanofi Pasteur
[Men07]; UNICEF (RDT distribution and training)
FX This work was financially supported by the French Ministry of Foreign
Affairs [FSP No. 2005-174] by Sanofi Pasteur [contract Men07] and UNICEF
(RDT distribution and training in 2009).
NR 29
TC 5
Z9 6
U1 1
U2 5
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0035-9203
EI 1878-3503
J9 T ROY SOC TROP MED H
JI Trans. Roy. Soc. Trop. Med. Hyg.
PD JAN
PY 2014
VL 108
IS 1
BP 6
EP 12
DI 10.1093/trstmh/trt104
PG 7
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 281WR
UT WOS:000329132200003
PM 24300442
ER
PT J
AU Costa, F
Porter, FH
Rodrigues, G
Farias, H
de Faria, MT
Wunder, EA
Osikowicz, LM
Kosoy, MY
Reis, MG
Ko, AI
Childs, JE
AF Costa, Federico
Porter, Fleur Helena
Rodrigues, Gorete
Farias, Helena
de Faria, Marcus Tucunduva
Wunder, Elsio A.
Osikowicz, Lynn M.
Kosoy, Michael Y.
Reis, Mitermayer Galvao
Ko, Albert I.
Childs, James E.
TI Infections by Leptospira interrogans, Seoul Virus, and Bartonella spp.
Among Norway Rats (Rattus norvegicus) from the Urban Slum Environment in
Brazil
SO VECTOR-BORNE AND ZOONOTIC DISEASES
LA English
DT Article
DE Leptospira interrogans; Seoul virus; Bartonella spp; Norway rats (Rattus
norvegicus); Brazil
ID HANTAVIRUS PULMONARY SYNDROME; RODENTS; POPULATION; BALTIMORE; ZOONOSES;
EPIDEMIC; THAILAND; MARYLAND; CITY; USA
AB Norway rats (Rattus norvegicus) are reservoir hosts for zoonotic pathogens that cause significant morbidity and mortality in humans. Studies evaluating the prevalence of zoonotic pathogens in tropical Norway rat populations are rare, and data on co-infection with multiple pathogens are nonexistent. Herein, we describe the prevalence of leptospiral carriage, Seoul virus (SEOV), and Bartonella spp. infection independently, in addition to the rates of co-infection among urban, slum-dwelling Norway rats in Salvador, Brazil, trapped during the rainy season from June to August of 2010. These data were complemented with previously unpublished Leptospira and SEOV prevalence information collected in 1998. Immunofluorescence staining of kidney impressions was used to identify Leptospira interrogans in 2010, whereas isolation was used in 1998, and western blotting was used to detect SEOV antibodies in 2010, whereas enzyme-linked immunosorbent assay (ELISA) was used in 1998: in 2010, Bartonella spp. were isolated from a subsample of rats. The most common pathogen in both years was Leptospira spp. (83%, n=142 in 1998, 63%, n=84 in 2010). SEOV was detected in 18% of individuals in both 1998 and 2010 (n=78 in 1998; n=73 in 2010), and two species of Bartonella were isolated from 5 of 26 rats (19%) tested in 2010. The prevalence of all agents increased significantly with rat mass/age. Acquisition of Leptospira spp. occurred at a younger mass/age than SEOV and Bartonella spp. infection, suggesting differences in the transmission dynamics of these pathogens. These data indicate that Norway rats in Salvador serve as reservoir hosts for all three of these zoonotic pathogens and that the high prevalence of leptospiral carriage in Salvador rats poses a high degree of risk to human health.
C1 [Costa, Federico; Reis, Mitermayer Galvao] Minist Saude, Ctr Pesquisas Goncalo Moniz, Fundacao Oswaldo Cruz, BR-40296710 Salvador, BA, Brazil.
[Costa, Federico; Porter, Fleur Helena; Wunder, Elsio A.; Ko, Albert I.] Yale Univ, Div Epidemiol Microbial Dis, Sch Publ Hlth, New Haven, CT USA.
[Rodrigues, Gorete; Farias, Helena] Minist Saude, Ctr Controle Zoonoses, Secretaria Municipal Saude, Salvador, BA, Brazil.
[de Faria, Marcus Tucunduva] Embrapa Amazonia Orienta, Belem, Para, Brazil.
[Osikowicz, Lynn M.; Kosoy, Michael Y.] Ctr Dis Control & Prevent, DVBID, Ft Collins, CO USA.
[Childs, James E.] Yale Univ, Sch Med, Dept Epidemiol & Publ Hlth, New Haven, CT 06510 USA.
[Childs, James E.] Yale Univ, Sch Med, Ctr Ecoepidemiol, New Haven, CT USA.
RP Costa, F (reprint author), Minist Saude, Ctr Pesquisas Goncalo Moniz, Fundacao Oswaldo Cruz, Rua Waldemar Falcao 121, BR-40296710 Salvador, BA, Brazil.
RI Ko, Albert/P-2343-2015; Wunder, Elsio/C-2733-2013; Costa,
Federico/G-1838-2015
OI Costa, Federico/0000-0001-6951-2336
FU Secretariat of Health Surveillance; Oswaldo Cruz Foundation; National
Institutes of Health [R01 AI052473, U01 AI088752, R01 TW009504, R24
TW007988, R25 TW009338, D43 TW00919]; CAPES (Coordination for the
Improvement of Higher Education Personnel/Ministry of Education/Brazil)
FX We would like to thank the staff of Centro de Controle de Zoonoses from
Salvador for their assistance in conducting the study and Julia Schoen
for assisting with database management; Ying Bai for the Bartonella spp.
sequencing; and Kate Hacker for her critical advice during the
preparation of the manuscript. This work was supported by the
Secretariat of Health Surveillance, the Oswaldo Cruz Foundation and the
National Institutes of Health (grants R01 AI052473, U01 AI088752, R01
TW009504, R24 TW007988, R25 TW009338 and D43 TW00919) and CAPES
(Coordination for the Improvement of Higher Education Personnel/Ministry
of Education/Brazil).
NR 54
TC 19
Z9 21
U1 0
U2 11
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1530-3667
EI 1557-7759
J9 VECTOR-BORNE ZOONOT
JI Vector-Borne Zoonotic Dis.
PD JAN 1
PY 2014
VL 14
IS 1
BP 33
EP 40
DI 10.1089/vbz.2013.1378
PG 8
WC Public, Environmental & Occupational Health; Infectious Diseases
SC Public, Environmental & Occupational Health; Infectious Diseases
GA 284ZE
UT WOS:000329360400004
PM 24359425
ER
PT J
AU Lubelczyk, C
Elias, SP
Kantar, L
Albert, J
Hansen, S
Saxton-Shaw, K
MacMillan, K
Smith, LB
Eisen, R
Swope, B
Smith, RP
Mutebi, JP
AF Lubelczyk, Charles
Elias, Susan P.
Kantar, Lee
Albert, Jennifer
Hansen, Stephen
Saxton-Shaw, Kali
MacMillan, Katharine
Smith, Leticia B.
Eisen, Rebecca
Swope, Bethany
Smith, Robert Pease
Mutebi, John-Paul
TI Detection of Eastern Equine Encephalitis Virus Antibodies in Moose
(Alces americana), Maine, 2010
SO VECTOR-BORNE AND ZOONOTIC DISEASES
LA English
DT Article
DE Eastern equine encephalitis virus; Moose; Alces Americana; Maine;
Mosquitos
ID WHITE-TAILED DEER; NORTHEASTERN UNITED-STATES; ENCEPHALOMYELITIS;
MOSQUITOS; TRANSMISSION; CONNECTICUT; BLOODMEALS; MICHIGAN; OUTBREAK;
VECTORS
AB Moose sera were collected from harvested animals during the 2010 hunting season in Maine. Of the 145 serum samples screened by plaque reduction neutralization test (PRNT), 16 (11%) had antibodies to eastern equine encephalitis virus (EEEV). Positive samples were collected from Aroostook County (n=13), Somerset County (n=2), and Piscataquis County (n=1) in northern and central Maine. Preliminary mosquito surveillance revealed the presence of enzootic and bridge vectors mosquitoes, including Culiseta (Climacura) melanura (Coquillett), Aedes (Aedimorphus) vexans (Meigen), and Coquillettidia (Coquillettidia) perturbans (Walker). Select mosquito species were tested by RT-PCR for the presence of EEEV. None were positive. This is the first report of EEEV in moose from Maine.
C1 [Lubelczyk, Charles; Elias, Susan P.; Smith, Leticia B.; Smith, Robert Pease] Maine Med Ctr, Res Inst, Vector Borne Dis Lab, South Portland, ME USA.
[Kantar, Lee] Maine Dept Inland Fisheries & Wildlife, Bangor, ME USA.
[Albert, Jennifer; Hansen, Stephen] Univ Maine, Dept Biol, Ft Kent, ME USA.
[Saxton-Shaw, Kali; MacMillan, Katharine; Eisen, Rebecca; Swope, Bethany; Mutebi, John-Paul] Ctr Dis Control & Prevent, Ft Collins, CO USA.
RP Lubelczyk, C (reprint author), Maine Med Ctr, Res Inst, Vector Borne Dis Lab, 81 Res Dr, Scarborough, ME 04074 USA.
EM lubelc@mmc.org
NR 31
TC 2
Z9 3
U1 1
U2 9
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1530-3667
EI 1557-7759
J9 VECTOR-BORNE ZOONOT
JI Vector-Borne Zoonotic Dis.
PD JAN 1
PY 2014
VL 14
IS 1
BP 77
EP 81
DI 10.1089/vbz.2012.1172
PG 5
WC Public, Environmental & Occupational Health; Infectious Diseases
SC Public, Environmental & Occupational Health; Infectious Diseases
GA 284ZE
UT WOS:000329360400011
PM 24359417
ER
PT J
AU Larson, TC
Franzblau, A
Lewin, M
Goodman, AB
Antao, VC
AF Larson, Theodore C.
Franzblau, Alfred
Lewin, Michael
Goodman, Alyson B.
Antao, Vinicius C.
TI Impact of Body Mass Index on the Detection of Radiographic Localized
Pleural Thickening
SO ACADEMIC RADIOLOGY
LA English
DT Article
DE Radiograph; pneumoconiosis; predictive values
ID CHEST RADIOGRAPHS; ASBESTOS; EXPOSURE; OBESITY; WORKERS; VERMICULITE;
OVERWEIGHT; DISEASES; ADULTS; LIBBY
AB Rationale and Objectives: Subpleural fat can be difficult to distinguish from localized pleural thickening (LPT), a marker of asbestos exposure, on chest radiographs. The aims of this study were to examine the influence of body mass index (BMI) on the-performance of radiograph readers when classifying LPT and to model the risk of false test results with varying BMI.
Materials and Methods: Subjects (n = 200) were patients being screened or treated for asbestos-related health outcomes. A film chest radiograph, a digital chest radiograph, and a high-resolution computed tomography (HRCT) chest scan were collected from each subject. All radiographs were independently read by seven B readers and scored using the International Labour Office system. HRCT scans, read by three experienced thoracic radiologists, served as the gold standard for the presence of LPT. We calculated measures of radiograph reader performance, including sensitivity and specificity, for each image modality. We also used logistic regression to estimate the probability of a false-positive and a false-negative result while controlling for covariates.
Results: The proportion of false-positive readings correlated with BMI. While controlling for covariates, regression modeling showed the probability of a false-positive result increased with increasing BMI category, younger age, not having pleural calcification, and among subjects not reporting occupational or household contact asbestos exposure.
Conclusions: Clinicians should be cautious when-evaluating-radiographs of younger obese persons for the presence of asbestos-related pleural plaque, particularly in populations having an anticipated low or background prevalence of LPT.
C1 [Larson, Theodore C.; Lewin, Michael; Antao, Vinicius C.] Agcy Tox Subst & Dis Registry, Div Toxicol & Human Hlth Sci, Atlanta, GA 30341 USA.
[Franzblau, Alfred] Univ Michigan, Sch Publ Hlth, Dept Environm Hlth Sci, Ann Arbor, MI 48109 USA.
[Goodman, Alyson B.] Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA USA.
RP Larson, TC (reprint author), Agcy Tox Subst & Dis Registry, Div Toxicol & Human Hlth Sci, 4770 Buford Highway NE,MS F57, Atlanta, GA 30341 USA.
EM TLarson@cdc.gov
NR 27
TC 4
Z9 4
U1 0
U2 4
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1076-6332
EI 1878-4046
J9 ACAD RADIOL
JI Acad. Radiol.
PD JAN
PY 2014
VL 21
IS 1
BP 3
EP 10
DI 10.1016/j.acra.2013.09.014
PG 8
WC Radiology, Nuclear Medicine & Medical Imaging
SC Radiology, Nuclear Medicine & Medical Imaging
GA 280HI
UT WOS:000329018900002
PM 24331259
ER
PT J
AU Jhung, MA
D'Mello, T
Perez, A
Aragon, D
Bennett, NM
Cooper, T
Farley, MM
Fowler, B
Grube, SM
Hancock, EB
Lynfield, R
Morin, C
Reingold, A
Ryan, P
Schaffner, W
Sharangpani, R
Tengelsen, L
Thomas, A
Thurston, D
Yousey-Hindes, K
Zansky, S
Finelli, L
Chaves, SS
AF Jhung, Michael A.
D'Mello, Tiffany
Perez, Alejandro
Aragon, Deborah
Bennett, Nancy M.
Cooper, Tara
Farley, Monica M.
Fowler, Brian
Grube, Stephen M.
Hancock, Emily B.
Lynfield, Ruth
Morin, Craig
Reingold, Arthur
Ryan, Patricia
Schaffner, William
Sharangpani, Ruta
Tengelsen, Leslie
Thomas, Ann
Thurston, Diana
Yousey-Hindes, Kimberly
Zansky, Shelley
Finelli, Lyn
Chaves, Sandra S.
TI Hospital-onset influenza hospitalizations-United States, 2010-2011
SO AMERICAN JOURNAL OF INFECTION CONTROL
LA English
DT Article
DE Health care associated
ID CARE-ASSOCIATED INFECTIONS; NOSOCOMIAL TRANSMISSION; TRANSPLANT
RECIPIENTS; VIRUS-INFECTIONS; ADULTS; OUTBREAK; CHILDREN; DURATION;
LENGTH
AB Background: Seasonal influenza is responsible for more than 200,000 hospitalizations each year in the United States. Although hospital-onset (HO) influenza contributes to morbidity and mortality among these patients, little is known about its overall epidemiology.
Objective: We describe patients with HO influenza in the United States during the 2010-2011 influenza season and compare them with community-onset (CO) cases to better understand factors associated with illness.
Methods: We identified laboratory-confirmed, influenza-related hospitalizations using the Influenza Hospitalization Surveillance Network (FluSurv-NET), a network that conducts population-based surveillance in 16 states. CO cases had laboratory confirmation <= 3 days after hospital admission; HO cases had laboratory confirmation > 3 days after admission.
Results: We identified 172 (2.8%) HO cases among a total of 6,171 influenza-positive hospitalizations. HO and CO cases did not differ by age (P = .22), sex (P = .29), or race (P = .25). Chronic medical conditions were more common in HO cases (89%) compared with CO cases (78%) (P < .01), and a greater proportion of HO cases (42%) than CO cases (17%) were admitted to the intensive care unit (P < .01). The median length of stay after influenza diagnosis of HO cases (7.5 days) was greater than that of CO cases (3 days) (P < .01).
Conclusion: HO cases had greater length of stay and were more likely to be admitted to the intensive care unit or die compared with CO cases. HO influenza may play a role in the clinical outcome of hospitalized patients, particularly among those with chronic medical conditions. Published by Elsevier Inc. on behalf of the Association for Professionals in Infection Control and Epidemiology, Inc.
C1 [Jhung, Michael A.; D'Mello, Tiffany; Perez, Alejandro; Finelli, Lyn; Chaves, Sandra S.] Ctr Dis Control & Prevent, Influenza Div, Epidemiol & Prevent Branch, Atlanta, GA 30333 USA.
[Aragon, Deborah] Colorado Dept Publ Hlth & Environm, Denver, CO USA.
[Bennett, Nancy M.] Univ Rochester, Sch Med & Dent, Dept Med, Rochester, NY 14642 USA.
[Cooper, Tara] Rhode Isl Dept Hlth, Providence, RI 02908 USA.
[Farley, Monica M.] Emory Univ, Georgia Div Publ Hlth, Georgia Emerging Infect Program, Atlanta, GA 30322 USA.
[Fowler, Brian; Zansky, Shelley] Ohio Dept Hlth, Columbus, OH 43266 USA.
[Grube, Stephen M.] Oklahoma Dept Hlth, Oklahoma City, OK USA.
[Hancock, Emily B.] New Mexico Dept Hlth, Santa Fe, NM USA.
[Lynfield, Ruth; Morin, Craig] Minnesota Dept Hlth, St Paul, MN USA.
[Reingold, Arthur] Calif Emerging Infect Program, Oakland, CA USA.
[Ryan, Patricia] Maryland Dept Hlth & Mental Hyg, Baltimore, MD USA.
[Schaffner, William] Vanderbilt Univ, Sch Med, Dept Prevent Med, Nashville, TN 37212 USA.
[Sharangpani, Ruta] Michigan Dept Community Hlth, Lansing, MI USA.
[Tengelsen, Leslie] Idaho Dept Hlth & Welf, Boise, ID USA.
[Thomas, Ann] Oregon Publ Hlth Div, Portland, OR USA.
[Thurston, Diana] Salt Lake Valley Hlth Dept, Salt Lake City, UT USA.
[Yousey-Hindes, Kimberly] Yale Univ, Sch Publ Hlth, Connecticut Emerging Infect Program, New Haven, CT USA.
RP Jhung, MA (reprint author), Ctr Dis Control & Prevent, Influenza Div, 1600 Clifton Rd NE,MS A-32, Atlanta, GA 30333 USA.
EM MJhung@cdc.gov
OI Yousey-Hindes, Kimberly/0000-0002-9418-575X
NR 30
TC 6
Z9 6
U1 0
U2 2
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0196-6553
EI 1527-3296
J9 AM J INFECT CONTROL
JI Am. J. Infect. Control
PD JAN
PY 2014
VL 42
IS 1
BP 7
EP 11
DI 10.1016/j.ajic.2013.06.018
PG 5
WC Public, Environmental & Occupational Health; Infectious Diseases
SC Public, Environmental & Occupational Health; Infectious Diseases
GA 282IT
UT WOS:000329165200005
PM 24183534
ER
PT J
AU Zheteyeva, YA
Tosh, P
Patel, PR
Martinez, D
Kilborn, C
Awosika-Olumo, D
Khuwaja, S
Ibrahim, S
Ryder, A
Tohme, RA
Khudyakov, Y
Thai, H
Drobeniuc, J
Heseltine, G
Guh, AY
AF Zheteyeva, Yenlik A.
Tosh, Pritish
Patel, Priti R.
Martinez, Diana
Kilborn, Cindy
Awosika-Olumo, Debo
Khuwaja, Salma
Ibrahim, Syed
Ryder, Anthony
Tohme, Rania A.
Khudyakov, Yury
Thai, Hong
Drobeniuc, Jan
Heseltine, Gary
Guh, Alice Y.
TI Hepatitis B outbreak associated with a home health care agency serving
multiple assisted living facilities in Texas, 2008-2010
SO AMERICAN JOURNAL OF INFECTION CONTROL
LA English
DT Article
DE Blood glucose monitoring; Infection control; Patient safety
ID TRANSMISSION
AB We investigated a multifacility outbreak of acute hepatitis B virus infection involving 21 residents across 10 assisted living facilities in Texas during the period January 2008 through July 2010. Epidemiologic and laboratory data suggested that these infections belonged to a single outbreak. The only common exposure was receipt of assisted monitoring of blood glucose from the same home health care agency. Improved infection control oversight and training of assisted living facility and home health care agency personnel providing assisted monitoring of blood glucose is needed. Published by Elsevier Inc. on behalf of the Association for Professionals in Infection Control and Epidemiology, Inc.
C1 [Zheteyeva, Yenlik A.; Tosh, Pritish; Patel, Priti R.; Guh, Alice Y.] Ctr Dis Control & Prevent, Ctr Emerging & Zoonot Infect Dis, Div Healthcare Qual Promot, Atlanta, GA 30333 USA.
[Zheteyeva, Yenlik A.; Tosh, Pritish; Tohme, Rania A.] Ctr Dis Control & Prevent, Sci Educ & Profess Dev Program Off, Epidem Intelligence Serv, Atlanta, GA 30333 USA.
[Martinez, Diana; Kilborn, Cindy] Harris Cty Publ Hlth & Environm Serv, Houston, TX USA.
[Awosika-Olumo, Debo; Khuwaja, Salma] City Houston Dept Hlth & Human Serv, Houston, TX USA.
[Ibrahim, Syed] Montgomery Cty Publ Hlth Dept, Conroe, TX USA.
[Ryder, Anthony] Ft Bend Cty Hlth & Human Serv, Rosenberg, TX USA.
[Tohme, Rania A.; Khudyakov, Yury; Thai, Hong; Drobeniuc, Jan] Ctr Dis Control & Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Div Viral Hepatitis, Atlanta, GA 30333 USA.
[Heseltine, Gary] Texas Dept State Hlth Serv, Austin, TX USA.
RP Guh, AY (reprint author), Ctr Dis Control & Prevent, Div Healthcare Qual Promot, 1600 Clifton Rd NE,MS A-31, Atlanta, GA 30333 USA.
EM ggt4@cdc.gov
NR 10
TC 3
Z9 3
U1 0
U2 1
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0196-6553
EI 1527-3296
J9 AM J INFECT CONTROL
JI Am. J. Infect. Control
PD JAN
PY 2014
VL 42
IS 1
BP 77
EP 81
DI 10.1016/j.ajic.2013.06.016
PG 5
WC Public, Environmental & Occupational Health; Infectious Diseases
SC Public, Environmental & Occupational Health; Infectious Diseases
GA 282IT
UT WOS:000329165200021
PM 24176604
ER
PT J
AU Zhu, JL
Obel, C
Hasle, H
Rasmussen, SA
Li, J
Olsen, J
AF Zhu, Jin Liang
Obel, Carsten
Hasle, Henrik
Rasmussen, Sonja A.
Li, Jiong
Olsen, Jorn
TI Social Conditions for People With Down Syndrome: A Register-Based Cohort
Study in Denmark
SO AMERICAN JOURNAL OF MEDICAL GENETICS PART A
LA English
DT Article
DE Down syndrome; mosaic trisomy 21; social conditions; offspring
ID POPULATION; LIFE; CHILDREN; TRISOMY-21; FERTILITY; SURVIVAL; DISEASE;
HEALTH; HOSPITALIZATIONS; MORTALITY
AB Today, most persons with Down syndrome (DS) survive into middle age, but information on their social conditions as adults is limited. We addressed this knowledge gap using data from national registers in Denmark. We identified a national cohort of 1,998 persons with DS who were born between 1968 and 2007 (1,852 with standard trisomy 21, 80 with Robertsonian translocations and 66 with mosaicism) using the Danish Cytogenetic Register. We followed this cohort from 1980 to 2007. Information on social conditions (education, employment, source of income, marital status, etc.) was obtained by linkages to national registers, including the Integrated Database for Longitudinal Labor Market Research. For those aged 18 and older, more than 80% of persons with DS attended 10 years of primary school, with about 2% completing secondary or post-secondary education. About 4% obtained a full-time job, whereas the remaining mainly received public support from the government. Only a few (1-2%) of persons with DS were married or had a child. No significant differences in these social conditions were seen between males and females. More persons with mosaic DS attended secondary or post-secondary education, had a full-time job, were married, or had a child (18%, 28%, 15%, and 7%, respectively), compared with persons with standard DS (1%, 2%, 1%, and 1%, respectively). These data may provide families with better insight into social conditions and society with a better understanding of the social support needed for persons with DS. (c) 2013 Wiley Periodicals, Inc.
C1 [Zhu, Jin Liang; Obel, Carsten] Aarhus Univ, Dept Publ Hlth, Res Program Childrens Mental Hlth, DK-8000 Aarhus C, Denmark.
[Zhu, Jin Liang; Li, Jiong; Olsen, Jorn] Aarhus Univ, Dept Publ Hlth, Epidemiol Sect, DK-8000 Aarhus C, Denmark.
[Obel, Carsten] Aarhus Univ, Dept Publ Hlth, Sect Gen Practice, DK-8000 Aarhus C, Denmark.
[Hasle, Henrik] Aarhus Univ Hosp, Dept Pediat, DK-8000 Aarhus, Denmark.
[Rasmussen, Sonja A.] Ctr Dis Control & Prevent CDC, Atlanta, GA USA.
RP Zhu, JL (reprint author), Aarhus Univ, Dept Publ Hlth, Epidemiol Sect, Bartholins Alle 2, DK-8000 Aarhus C, Denmark.
EM zjl@soci.au.dk
RI li, jiong/L-6534-2014;
OI li, jiong/0000-0002-1716-8067; Hasle, Henrik/0000-0003-3976-9231
FU Centers for Disease Control and Prevention (CDC) [5 U10 DD000230-06];
European Research Council [260242]; Tryg Foundation [7-11-1155]
FX Grant sponsor: Centers for Disease Control and Prevention (CDC); Grant
number: #5 U10 DD000230-06; Grant sponsor: European Research Council;
Grant number: 260242; Grant sponsor: Tryg Foundation; Grant number:
7-11-1155.
NR 31
TC 3
Z9 3
U1 2
U2 11
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1552-4825
EI 1552-4833
J9 AM J MED GENET A
JI Am. J. Med. Genet. A
PD JAN
PY 2014
VL 164
IS 1
BP 36
EP 41
DI 10.1002/ajmg.a.36272
PG 6
WC Genetics & Heredity
SC Genetics & Heredity
GA 276FV
UT WOS:000328734900006
PM 24273114
ER
PT J
AU Jackson, JM
Crider, KS
Cragan, JD
Rasmussen, SA
Olney, RS
AF Jackson, Jodi M.
Crider, Krista S.
Cragan, Janet D.
Rasmussen, Sonja A.
Olney, Richard S.
TI Frequency of Prenatal Cytogenetic Diagnosis and Pregnancy Outcomes by
Maternal Race-Ethnicity, and the Effect on the Prevalence of Trisomy 21,
Metropolitan Atlanta, 1996-2005
SO AMERICAN JOURNAL OF MEDICAL GENETICS PART A
LA English
DT Article
DE trisomy 21; Down syndrome; prenatal; cytogenetics; congenital defect;
elective termination
ID DOWN-SYNDROME; BIRTH-DEFECTS; UNITED-STATES; AMNIOCENTESIS; POPULATION;
CALIFORNIA; WOMEN; ACCEPTANCE; EXPERIENCE
AB The prevalence of trisomy 21 has been reported to differ by race-ethnicity, however, the results are inconsistent and the cause of the differences is unknown. Using data from 1996 to 2005 from the Metropolitan Atlanta Congenital Defects Program (MACDP), we analyzed the use of prenatal cytogenetic testing and the subsequent use of elective termination among pregnancies affected with any MACDP-eligible birth defect and trisomy 21, by maternal race-ethnicity. We then examined whether these factors could explain the observed differences in the prevalence of trisomy 21 among race-ethnicity groups. Among all pregnancies with birth defects, prenatal cytogenetic testing as well as elective terminations after an abnormal prenatal cytogenetic test result were observed less frequently among Hispanic women than among non-Hispanic white women (odds ratio [OR] 0.66, 95% confidence interval [CI] 0.56-0.78, respectively). In pregnancies affected by trisomy 21, both the Hispanic and the non-Hispanic black populations had more live births (89.5% and 77.8%, respectively) and fewer elective terminations (5.7% and 15.2%, respectively) compared to the non-Hispanic white population (63.0% live births, 32.3% elective terminations). After adjusting for elective terminations, non-Hispanic white mothers had a higher live birth prevalence of trisomy 21 compared to non-Hispanic black (OR 0.64, 95% CI 0.54-0.76) or Hispanic mothers (OR 0.69, 95% CI 0.55-0.86). Overall, our data suggest that factors associated with decisions made about the use of prenatal testing, and about pregnancy management after testing, might play a large role in the race-ethnicity differences observed in the live birth prevalence of trisomy 21. (c) 2013 Wiley Periodicals, Inc.
C1 [Jackson, Jodi M.; Crider, Krista S.; Cragan, Janet D.; Rasmussen, Sonja A.; Olney, Richard S.] Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA USA.
RP Jackson, JM (reprint author), 1600 Clifton Rd,MS E-86, Atlanta, GA 30333 USA.
EM hwi4@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 25
TC 4
Z9 4
U1 1
U2 5
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1552-4825
EI 1552-4833
J9 AM J MED GENET A
JI Am. J. Med. Genet. A
PD JAN
PY 2014
VL 164
IS 1
BP 70
EP 76
DI 10.1002/ajmg.a.36247
PG 7
WC Genetics & Heredity
SC Genetics & Heredity
GA 276FV
UT WOS:000328734900011
PM 24273106
ER
PT J
AU Pratt, LA
Brody, DJ
AF Pratt, Laura A.
Brody, Debra J.
TI Implications of two-stage depression screening for identifying persons
with thoughts of self-harm
SO GENERAL HOSPITAL PSYCHIATRY
LA English
DT Article
DE Depression; Self-harm; Screening; PHQ-9; NHANES
ID PATIENT HEALTH QUESTIONNAIRE; PRIMARY-CARE PATIENTS; SUICIDAL IDEATION;
MAJOR DEPRESSION; CANCER-PATIENTS; OLDER-ADULTS; PHQ-9; ADOLESCENTS;
HEART; RISK
AB Objective: Persons with thoughts of self-harm may need evaluation for suicide risk. We examine the prevalence of thoughts of self-harm and whether persons with thoughts of self-harm are identified when two-stage depression screening is used.
Methods: Data are from the 2005-2010 National Health and Nutrition Examination Surveys. Persons responding positively to question nine of the Patient Health Questionnaire-9 (PHQ-9) are identified as having thoughts of self-harm. We compare two depression cutoff scores for the Patient Health Questionnaire-2 (PHQ-2) to see what percentage of persons with thoughts of self-harm would be identified as needing further screening with the PHQ-9.
Results: The prevalence of thoughts of self-harm was 3.5%. Persons 12-17 years old, poor and reporting fair or poor health were more likely to report thoughts of self-harm. A cutoff score of three on the PHQ-2 identified 49% of persons with thoughts of self-harm for further screening with the PHQ-9. A cut point of two increased the proportion of persons with thoughts of self-harm continuing for further screening to 76%.
Conclusions: Using a lower cutoff score, two, the PHQ-2 captures more persons with thoughts of self-harm. One quarter of persons with self-harm thoughts may not be identified for further screening when two-stage screening is used. Published by Elsevier Inc.
C1 [Pratt, Laura A.] Ctr Dis Control & Prevent, Off Anal & Epidemiol, Natl Ctr Hlth Stat, Atlanta, GA 30329 USA.
[Brody, Debra J.] Ctr Dis Control & Prevent, Div Hlth & Nutr Examinat Surveys, Natl Ctr Hlth Stat, Atlanta, GA 30329 USA.
RP Pratt, LA (reprint author), Natl Ctr Hlth Stat, 3311 Toledo Rd,Rm 6333, Hyattsville, MD 20782 USA.
EM lpratt@cdc.gov
NR 40
TC 3
Z9 3
U1 0
U2 6
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0163-8343
EI 1873-7714
J9 GEN HOSP PSYCHIAT
JI Gen. Hosp. Psych.
PD JAN-FEB
PY 2014
VL 36
IS 1
BP 119
EP 123
DI 10.1016/j.genhosppsych.2013.09.007
PG 5
WC Psychiatry
SC Psychiatry
GA 281OY
UT WOS:000329112100024
PM 24183490
ER
PT J
AU Simmons, GM
Frick, N
Wang, A
Miller, ME
Fragueiro, D
AF Simmons, G. M.
Frick, N.
Wang, A.
Miller, M. E.
Fragueiro, D.
TI Identifying information needs among children and teens living with
haemophilia
SO HAEMOPHILIA
LA English
DT Article
DE adolescents; children; disclosure; haemophilia; sports; transition
AB Transitioning from one life stage to the next can be difficult, but for those living with a chronic condition, it can be even more challenging. Children and adolescents with haemophilia need help to manage transitions while dealing with the complications of their disorder. The National Haemophilia Foundation (NHF), headquartered in New York City, has an extensive information centre on bleeding disorders, but it was not clear how much material existed on the topic of transition. The objectives of this project were to (i) assess the availability of literature about transition for children and adolescents living with haemophilia, (ii) determine which transition issues were the most relevant and (iii) develop and test information products that would address those transition issues. An inventory of NHF's resources and an environmental scan over the Internet was performed. Focus groups were conducted to determine messaging. Video prototypes containing messages were created, tested by focus groups and revised. The literature search yielded limited information available on transition for children and adolescents with haemophilia. Results of the formative research indicated that adolescents wanted more information on sports participation and disclosure of their condition (e.g. to peers, teachers, coaches, health care providers). Video was found to be the preferred delivery format. Children and adolescents living with haemophilia need information to help them transition through life. As a result of this study, two educational products were produced, but several more are recommended to guide these individuals in making healthy transitions into adulthood.
C1 [Simmons, G. M.] Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, Div Blood Disorders, Atlanta, GA 30333 USA.
[Frick, N.; Wang, A.] Natl Hemophilia Fdn, New York, NY USA.
[Miller, M. E.; Fragueiro, D.] ICF Int, Strateg Commun & Mkt Div, Rockville, MD USA.
RP Simmons, GM (reprint author), Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, Div Blood Disorders, 1600 Clifton Rd,MS E 64, Atlanta, GA 30333 USA.
EM gmsimmons@cdc.gov
FU CDC
FX This project was funded by CDC, under a contract to ICF International,
to research relevant information resources, find gaps in primary subject
areas and to determine the most appropriate messages to help youth with
haemophilia manage their condition as they transition to adulthood. The
authors acknowledge the members of the HANDI Evaluation Working Group
including: Maggie Gallarno of the University of Mississippi Medical
Center; Chasity L. Mullins, R.N., B.S.N., of the Vanderbilt University
Medical Center; Jean Marandola, R.N., M.S., from Rhode Island Hospital;
Marion Koerper, M.D., of the UCSF Haemophilia Program; Ruth Mulvany,
R.P.T. of the University of Tennessee; Regina Butler, R.N., Children's
Hospital of Philadelphia; Casey Nakatani of the Haemophilia Foundation
of Southern California; Deborah Adamkin of the Florida Haemophilia
Association; Rob Alexander of the Central Ohio Chapter of NHF; Ann
Henningfield of the Haemophilia Foundation of Michigan; and Brent Movitz
of the National Youth Leadership Institute. The authors thank Dawn
Rotellini, Michelle Rice and Jennifer Crawford of the National
Haemophilia Foundation for their support and guidance through the life
of the project. The authors thank Sally McAlister for her early
contributions to the conceptualization of this project. The authors also
thank the NHF Chapter Staff who assisted with recruitment efforts among
parent and adolescent participants and for informing the development and
increasing the potential utility of these two videos.
NR 13
TC 2
Z9 2
U1 0
U2 4
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1351-8216
EI 1365-2516
J9 HAEMOPHILIA
JI Haemophilia
PD JAN
PY 2014
VL 20
IS 1
BP 1
EP 8
DI 10.1111/hae.12223
PG 8
WC Hematology
SC Hematology
GA 276FG
UT WOS:000328733300001
PM 23809876
ER
PT J
AU Puetz, J
Soucie, JM
Kempton, CL
Monahan, PE
AF Puetz, J.
Soucie, J. M.
Kempton, C. L.
Monahan, P. E.
CA HTCN Investigators
TI Prevalent inhibitors in haemophilia B subjects enrolled in the Universal
Data Collection database
SO HAEMOPHILIA
LA English
DT Article
DE factor IX; haemophilia B; inhibitors; prevalence; race; Universal Data
Collection
ID PREVIOUSLY UNTREATED PATIENTS; FACTOR-IX; FACTOR-VIII; EFFICACY;
REGISTRY; SAFETY; COHORT; RISK
AB Several risk factors for inhibitors have recently been described for haemophilia A. It has been assumed that similar risk factors are also relevant for haemophilia B, but there is limited data to confirm this notion. The aim of this study was to determine the prevalence of and risk factors associated with inhibitors in haemophilia B. The database of the Universal Data Collection (UDC) project of the Centers for Disease Control for the years 1998-2011 was queried to determine the prevalence of inhibitors in haemophilia B subjects. In addition, disease severity, race/ethnicity, age, factor exposure and prophylaxis usage were evaluated to determine their impact on inhibitor prevalence. Of the 3785 male subjects with haemophilia B enrolled in the UDC database, 75 (2%) were determined to have an inhibitor at some point during the study period. Severe disease (OR 13.1, 95% CI 6.2-27.7), black race (OR 2.2, 95% CI 1.2-4.1), and age <11years (OR 2.5, 95% CI 1.5-4.0) were found to be significantly associated with having an inhibitor. There was insufficient data to determine if type of factor used and prophylaxis were associated with inhibitors. Inhibitors in haemophilia B are much less prevalent than haemophilia A, especially in patients with mild disease. Similar factors associated with inhibitors in haemophilia A also seem to be present for haemophilia B. The information collected by this large surveillance project did not permit evaluation of potential risk factors related to treatment approaches and exposures, and additional studies will be required.
C1 [Puetz, J.] St Louis Univ, Dept Pediat, Div Hematol Oncol, St Louis, MO 63104 USA.
[Soucie, J. M.] Ctr Dis Control & Prevent, Div Blood Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA USA.
[Kempton, C. L.] Emory Univ, Dept Pediat, Atlanta, GA 30322 USA.
[Kempton, C. L.] Emory Univ, Dept Hematol Oncol, Atlanta, GA 30322 USA.
[Monahan, P. E.] Univ N Carolina, Dept Pediat, Chapel Hill, NC USA.
[Monahan, P. E.] Natl Ctr Birth Defects & Dev Disabil, Div Blood Disorders, Atlanta, GA USA.
RP Puetz, J (reprint author), St Louis Univ, Dept Pediat, Div Hematol Oncol, 1465 S Grand, St Louis, MO 63104 USA.
EM puetzjj@slu.edu
RI Kerlin, Bryce/E-3369-2011
OI Kerlin, Bryce/0000-0002-1756-8271
FU Prevention of Bleeding Disorder Complications through Regional
Hemophilia Treatment Centers
FX The authors acknowledge the assistance of the Universal Data Collection
Working Group and the Centers for Disease Control for their help in
designing and completing this study, and for the use of the UDC data.
The collection and analysis of the data were supported by the
Grant/Cooperative Agreement 'Prevention of Bleeding Disorder
Complications through Regional Hemophilia Treatment Centers'. We also
thank the patients, staff members and physicians of the Hemophilia
Treatment Centers who contributed to the UDC database, and especially
those who responded to our queries regarding the data.
NR 19
TC 16
Z9 17
U1 1
U2 3
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1351-8216
EI 1365-2516
J9 HAEMOPHILIA
JI Haemophilia
PD JAN
PY 2014
VL 20
IS 1
BP 25
EP 31
DI 10.1111/hae.12229
PG 7
WC Hematology
SC Hematology
GA 276FG
UT WOS:000328733300008
PM 23855900
ER
PT J
AU Frieden, TR
King, SMC
Wright, JS
AF Frieden, Thomas R.
King, Sallyann M. Coleman
Wright, Janet S.
TI Protocol-Based Treatment of Hypertension A Critical Step on the Pathway
to Progress
SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
LA English
DT Editorial Material
ID BLOOD-PRESSURE; AWARENESS; TRENDS
C1 [Frieden, Thomas R.; King, Sallyann M. Coleman; Wright, Janet S.] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
RP Frieden, TR (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd NE,MS D-14, Atlanta, GA 30333 USA.
EM tfrieden@cdc.gov
NR 7
TC 18
Z9 18
U1 0
U2 1
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 515 N STATE ST, CHICAGO, IL 60654-0946 USA
SN 0098-7484
EI 1538-3598
J9 JAMA-J AM MED ASSOC
JI JAMA-J. Am. Med. Assoc.
PD JAN 1
PY 2014
VL 311
IS 1
BP 21
EP 22
DI 10.1001/jama.2013.282615
PG 2
WC Medicine, General & Internal
SC General & Internal Medicine
GA 282HN
UT WOS:000329161400010
PM 24231925
ER
PT J
AU King, BA
Tynan, MA
Dube, SR
Arrazola, R
AF King, Brian A.
Tynan, Michael A.
Dube, Shanta R.
Arrazola, Rene
TI Flavored-Little-Cigar and Flavored-Cigarette Use Among US Middle and
High School Students
SO JOURNAL OF ADOLESCENT HEALTH
LA English
DT Article
ID UNITED-STATES; TOBACCO; CONSUMPTION; BEHAVIOR; SMOKING; BRANDS; ADULTS;
YOUTH
AB Purpose: Flavors can mask the harshness and taste of tobacco, making flavored tobacco products appealing to youth. We assessed the prevalence and correlates of flavored-little-cigar and flavored-cigarette use among U.S. middle and high school students in 2011.
Methods: Data were obtained from the 2011 National Youth Tobacco Survey, a nationally representative school-based survey of U.S. students in grades 6-12. National estimates of current flavored-little-cigar use, flavored-cigarette use, and combined use of either product were calculated overall and among current smokers by respondent characteristics, including sex, race/ethnicity, school level, and grade. Additionally, intention to quit tobacco and smoking frequency were assessed by flavored product use.
Results: The overall prevalence of current use was 4.2% for flavored cigarettes, 3.3% for flavored little cigars, and 6.3% for either product. Among current cigar smokers, 35.9% reported using flavored little cigars, and among current cigarette smokers, 35.4% reported using flavored cigarettes. Among current cigar or cigarette smokers, 42.4% reported using flavored little cigars or flavored cigarettes. Flavored product use among current smokers was higher among non-Hispanic whites than among blacks and Hispanics, higher among high school students than middle school students, and increased with grade. Among cigar smokers, prevalence of no intention to quit tobacco was higher among flavored-little-cigar users (59.7%) than nonusers (49.3%).
Conclusions: More than two fifths of U.S. middle and high school smokers report using flavored little cigars or flavored cigarettes, and disparities in the use of these products exist across subpopulations. Efforts are needed to reduce flavored tobacco product use among youth. Published by Elsevier Inc. on behalf of Society for Adolescent Health and Medicine.
C1 [King, Brian A.; Tynan, Michael A.; Dube, Shanta R.; Arrazola, Rene] Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Off Smoking & Hlth, Atlanta, GA 30341 USA.
RP King, BA (reprint author), Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Off Smoking & Hlth, 4770 Buford Highway,MS F-79, Atlanta, GA 30341 USA.
EM baking@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 33
TC 40
Z9 40
U1 0
U2 3
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1054-139X
EI 1879-1972
J9 J ADOLESCENT HEALTH
JI J. Adolesc. Health
PD JAN
PY 2014
VL 54
IS 1
BP 40
EP 46
PG 7
WC Psychology, Developmental; Public, Environmental & Occupational Health;
Pediatrics
SC Psychology; Public, Environmental & Occupational Health; Pediatrics
GA 280WV
UT WOS:000329062400007
PM 24161587
ER
PT J
AU Arrazola, RA
Kuiper, NM
Dube, SR
AF Arrazola, Rene A.
Kuiper, Nicole M.
Dube, Shanta R.
TI Patterns of Current Use of Tobacco Products Among US High School
Students for 2000-2012-Findings From the National Youth Tobacco Survey
SO JOURNAL OF ADOLESCENT HEALTH
LA English
DT Article
ID CIGARETTE SMOKERS; UNITED-STATES; ADOLESCENTS; DEPENDENCE
AB Purpose: The purpose of this study was to assess patterns and trends of tobacco use among high school students to better understand which products are used individually or concurrently.
Methods: Data from the National Youth Tobacco Survey from 2000 through 2012 were used to assess patterns and trends of current tobacco use (cigarettes, cigars, smokeless tobacco, and other tobacco products) among U. S. high school students. We assessed use of products individually and concurrently.
Results: During 2000-2012, overall linear declines were observed in current use of any tobacco product from 33.6% to 20.4% (p < .05), current use of only 1 tobacco product, from 18.8% to 10.5% (p < .05), and current poly tobacco use, from 14.7% to 9.9% (p < .05), among high school students. Overall current use of only cigarettes had both a linear decline, from 14.0% to 4.7%, as well as a quadratic trend.
Conclusions: During 2000-2012, the most significant overall decline observed was for students who reported smoking only cigarettes. The results suggest that more data on the use of multiple tobacco products, not just cigarettes, is needed to guide tobacco prevention and control policies and programs. Published by Elsevier Inc. on behalf of Society for Adolescent Health and Medicine.
C1 [Arrazola, Rene A.; Kuiper, Nicole M.; Dube, Shanta R.] Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Off Smoking & Hlth, Atlanta, GA 30341 USA.
RP Arrazola, RA (reprint author), Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Off Smoking & Hlth, 4770 Buford Highway NE,MS F-79, Atlanta, GA 30341 USA.
EM RArrazola@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 20
TC 29
Z9 29
U1 1
U2 5
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1054-139X
EI 1879-1972
J9 J ADOLESCENT HEALTH
JI J. Adolesc. Health
PD JAN
PY 2014
VL 54
IS 1
BP 54
EP U173
DI 10.1016/j.jadohealth.2013.08.003
PG 16
WC Psychology, Developmental; Public, Environmental & Occupational Health;
Pediatrics
SC Psychology; Public, Environmental & Occupational Health; Pediatrics
GA 280WV
UT WOS:000329062400009
PM 24074604
ER
PT J
AU Lowry, R
Crosby, AE
Brener, ND
Kann, L
AF Lowry, Richard
Crosby, Alexander E.
Brener, Nancy D.
Kann, Laura
TI Suicidal Thoughts and Attempts Among US High School Students: Trends and
Associated Health-Risk Behaviors, 1991-2011
SO JOURNAL OF ADOLESCENT HEALTH
LA English
DT Article
ID ADOLESCENT SUICIDE; UNITED-STATES; SUBSTANCE USE; PRIMARY-CARE;
IDEATION; PREVENTION
AB Purpose: To describe secular trends in suicidal thoughts and attempts and the types of health-risk behaviors associated with suicidal thoughts and attempts among U. S. high school students.
Methods: Data were analyzed from 11 national Youth Risk Behavior Surveys conducted biennially during 1991-2011. Each survey employed a nationally representative sample of students in grades 9-12 and provided data from approximately 14,000 students. Using sex-stratified logistic regression models that controlled for race/ethnicity and grade, we analyzed secular trends in the prevalence of suicidal thoughts and attempts. Adjusted prevalence ratios (APR) were calculated to measure associations between suicide risk and a broad range of health-risk behaviors.
Results: During 1991-2011, among female students, both suicidal thoughts (seriously considered suicide; made a plan to attempt suicide) and attempts (any attempt; attempt with injury requiring medical treatment) decreased significantly; among male students, only suicidal thoughts decreased significantly. During 2011, compared with students with no suicidal thoughts or attempts, the health-risk behaviors most strongly associated with suicide attempts among female students were injection drug use (APR=12.8), carrying a weapon on school property (APR=9.7), and methamphetamine use (APR=8.7); among male students, the strongest associations were for IDU (APR=22.4), using vomiting/laxatives for weight control (APR=17.1), and having been forced to have sex (APR=14.8).
Conclusions: School-based suicide prevention programs should consider confidential screening for health-risk behaviors that are strongly associated with suicide attempts to help identify students at increased risk for suicide and provide referrals to suicide and other prevention services (e. g., substance abuse and violence prevention) as appropriate. Published by Elsevier Inc. on behalf of Society for Adolescent Health and Medicine.
C1 [Lowry, Richard; Brener, Nancy D.; Kann, Laura] Natl Ctr HIV AIDS, Div Adolescent & Sch Hlth, Atlanta, GA USA.
[Crosby, Alexander E.] Ctr Dis Control & Prevent, Natl Ctr Injury Prevent & Control, Div Violence Prevent, Atlanta, GA 30341 USA.
RP Lowry, R (reprint author), Ctr Dis Control & Prevent, Div Adolescent & Sch Hlth, 4770 Buford Hwy NE Mailstop K-33, Atlanta, GA 30341 USA.
EM rxl1@cdc.gov
NR 39
TC 7
Z9 7
U1 4
U2 16
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1054-139X
EI 1879-1972
J9 J ADOLESCENT HEALTH
JI J. Adolesc. Health
PD JAN
PY 2014
VL 54
IS 1
BP 100
EP 108
DI 10.1016/j.jadohealth.2013.07.024
PG 9
WC Psychology, Developmental; Public, Environmental & Occupational Health;
Pediatrics
SC Psychology; Public, Environmental & Occupational Health; Pediatrics
GA 280WV
UT WOS:000329062400016
PM 24035267
ER
PT J
AU Kossover, RA
Chi, CJ
Wise, ME
Tran, AH
Chande, ND
Perz, JF
AF Kossover, Rachel A.
Chi, Carolyn J.
Wise, Matthew E.
Tran, Alvin H.
Chande, Neha D.
Perz, Joseph F.
TI Infection Prevention and Control Standards in Assisted Living
Facilities: Are Residents' Needs Being Met?
SO JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
LA English
DT Article
DE Assisted living; health policy; health care-associated infection;
infection prevention; health care workers
ID BLOOD-GLUCOSE; CENTRAL MARYLAND; HEALTH-CARE; TRANSMISSION; OUTBREAKS;
VIRGINIA; ILLNESS
AB Background: Assisted living facilities (ALFs) provide housing and care to persons unable to live independently, and who often have increasing medical needs. Disease outbreaks illustrate challenges of maintaining adequate resident protections in these facilities. Objectives: Describe current state laws on assisted living admissions criteria, medical oversight, medication administration, vaccination requirements, and standards for infection control training.
Methods: We abstracted laws and regulations governing assisted living facilities for the 50 states using a structured abstraction tool. Selected characteristics were compared according to the time period in which the regulation took effect. Selected state health departments were queried regarding outbreaks identified in assisted living facilities.
Results: Of the 50 states, 84% specify health-based admissions criteria to assisted living facilities; 60% require licensed health care professionals to oversee medical care; 88% specifically allow subcontracting with outside entities to provide routine medical services onsite; 64% address medication administration by assisted living facility staff; 54% specify requirements for some form of initial infection control training for all staff; 50% require reporting of disease outbreaks to the health department; 18% specify requirements to offer or require vaccines to staff; 30% specify requirements to offer or require vaccines to residents. Twelve states identified approximately 1600 outbreaks from 2010 to 2013, with influenza or norovirus infections predominating.
Conclusions: There is wide variation in how assisted living facilities are regulated in the United States. States may wish to consider regulatory changes that ensure safe health care delivery, and minimize risks of infections, outbreaks of disease, and other forms of harm among assisted living residents. Published by Elsevier Inc. on behalf of American Medical Directors Association, Inc.
C1 [Kossover, Rachel A.; Chi, Carolyn J.; Wise, Matthew E.; Tran, Alvin H.; Chande, Neha D.; Perz, Joseph F.] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA 30333 USA.
RP Kossover, RA (reprint author), Ctr Dis Control & Prevent, Div Healthcare Qual Promot, 1600 Clifton Rd,MS A-31, Atlanta, GA 30333 USA.
EM gvb7@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 39
TC 3
Z9 3
U1 1
U2 7
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1525-8610
EI 1538-9375
J9 J AM MED DIR ASSOC
JI J. Am. Med. Dir. Assoc.
PD JAN
PY 2014
VL 15
IS 1
BP 47
EP 53
DI 10.1016/j.jamda.2013.09.011
PG 7
WC Geriatrics & Gerontology
SC Geriatrics & Gerontology
GA 280WE
UT WOS:000329060700008
PM 24239014
ER
PT J
AU Shcherbik, S
Sergent, SB
Davis, WG
Shu, B
Barnes, J
Kiseleva, I
Larionova, N
Klimov, A
Bousse, T
AF Shcherbik, Svetlana
Sergent, Sheila B.
Davis, William G.
Shu, Bo
Barnes, John
Kiseleva, Irina
Larionova, Natalie
Klimov, Alexander
Bousse, Tatiana
TI Application of real time RT-PCR for the genetic homogeneity and
stability tests of the seed candidates for live attenuated influenza
vaccine production
SO JOURNAL OF VIROLOGICAL METHODS
LA English
DT Article
DE Influenza virus; Reassortants; Live vaccine; Real time RT-PCR;
Homogeneity test
ID VIRUS VACCINE; RESTRICTION ANALYSIS; GENOME COMPOSITION; ASSAY;
VALIDATION; EFFICACY; STRAINS; H1N1; RNA; H7
AB Development and improvement of quality control tests for live attenuated vaccines are a high priority because of safety concerns. Live attenuated influenza vaccine (LAIV) viruses are 6:2 reassortants containing the hemagglutinin (HA) and neuraminidase (NA) gene segments from circulating influenza viruses to induce protective immune responses, and the six internal gene segments from a cold-adapted Master Donor Virus (MDV). LAIV candidate viruses for the 2012-2013 seasons, A/Victoria/361/2011-CDC-LV1 (LV1) and B/Texas/06/2011-CDC-LV2B (LV2B), were created by classical reassortment of A/Victoria/361/2011 and MDV-A A/Leningrad/134/17/57 (H2N2) or B/Texas/06/2011 and MDV-B B/USSR/60/69. In an attempt to provide better identity and stability testing for quality control of LV1 and LV2B, sensitive real-time RT-PCR assays (rRT-PCR) were developed to detect the presence of undesired gene segments (HA and NA from MDV and the six internal genes from the seasonal influenza viruses). The sensitivity of rRT-PCR assays designed for each gene segment ranged from 0.08 to 0.8EID50 (50% of Egg Infectious Dose) per reaction for the detection of undesired genes in LV1 and from 0.1 to 1 EID50 per reaction for the detection of undesired genes in LV2B. No undesired genes were detected either before or after five passages of LV1 or LV2B in eggs. The complete genome sequencing of LV1 and LV2B confirmed the results of rRT-PCR, demonstrating the utility of the new rRT-PCR assays to provide the evidence for the homogeneity of the prepared vaccine candidate. Published by Elsevier B.V.
C1 [Shcherbik, Svetlana; Sergent, Sheila B.; Davis, William G.; Shu, Bo; Barnes, John; Klimov, Alexander; Bousse, Tatiana] Ctr Dis Control & Prevent, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
[Shcherbik, Svetlana; Sergent, Sheila B.; Davis, William G.] Battelle Mem Inst, Atlanta, GA 30329 USA.
[Kiseleva, Irina; Larionova, Natalie] Russian Acad Med Sci, Inst Expt Med, Dept Virol, St Petersburg, Russia.
RP Bousse, T (reprint author), Ctr Dis Control & Prevent, Virol Surveillance & Diag Branch, Influenza Div, Natl Ctr Immunizat & Resp Dis, Mail Stop G-16,1600 Clifton Rd, Atlanta, GA 30333 USA.
EM tbousse@cdc.gov
RI Kiseleva, Irina/E-6555-2014;
OI Kiseleva, Irina/0000-0002-3892-9873; Larionova,
Natalie/0000-0003-1171-3383
FU CDC
FX We thank Larisa Rudenko (IEM, St Petersburg, Russia) for providing MDVs,
serum to MDVs and protocols for generation and characterization of
reassortants. We thank Xiyan Xu for providing wt viruses, Amanda Balish
for technical assistance on the project, Jan Mabry for help in
preparation of serum to reassortant virus, Angie Foust for help in
lyophilization of reassortant, Stephen Lindstrom for providing
primers/probe sets for universal detection of H3 and H2 subtypes and
detection of PB1 gene of LAIV-A virus (FluMist). We also thank Nancy Cox
and Julie Villanueva for the support of project development at CDC. The
work described in this report was supported by the World Health
Organization (WHO) and the U.S. Department of Health and Human Services
Biomedical Advanced Research and Development Authority (HHS BARDA).
NR 39
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PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0166-0934
EI 1879-0984
J9 J VIROL METHODS
JI J. Virol. Methods
PD JAN
PY 2014
VL 195
BP 18
EP 25
DI 10.1016/j.jviromet.2013.09.003
PG 8
WC Biochemical Research Methods; Biotechnology & Applied Microbiology;
Virology
SC Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology;
Virology
GA 277FQ
UT WOS:000328804800003
PM 24056261
ER
PT J
AU Worwa, G
Andrade, CC
Thiemann, TC
Park, B
Maharaj, PD
Anishchenko, M
Brault, AC
Reisen, WK
AF Worwa, Gabriella
Andrade, Christy C.
Thiemann, Tara C.
Park, Bborie
Maharaj, Payal D.
Anishchenko, Michael
Brault, Aaron C.
Reisen, William K.
TI Allele-specific qRT-PCR demonstrates superior detection of single
nucleotide polymorphisms as genetic markers for West Nile virus compared
to Luminex (R) and quantitative sequencing
SO JOURNAL OF VIROLOGICAL METHODS
LA English
DT Article
DE West Nile virus; Genetic marker; Luminex (R) technology; Quantitative
sequencing; qRT-PCR; Fitness competition
ID VIRULENCE; EVOLUTION; REPLICATION; MUTATIONS; MOSQUITOS; ARBOVIRUS;
ISOLATE; CELLS
AB To enable in vivo and in vitro competitive fitness comparisons among West Nile viruses (WNV), three reference viruses were marked genetically by site-directed mutagenesis with five synonymous nucleotide substitutions in the envelope gene region of the genome. Phenotypic neutrality of the mutants was assessed experimentally by competitive replication in cell culture and genetic stability of the substituted nucleotides was confirmed by direct sequencing.
Luminex (R) technology, quantitative sequencing and quantitative RT-PCR (qRT-PCR) were compared in regard to specificity, sensitivity and accuracy for quantitation of wildtype and genetically marked viruses in mixed samples based on RNA obtained from samples of known viral titers. Although Luminex (R) technology and quantitative sequencing provided semi-quantitative or qualitative measurements, a sequence-specific primer extension approach using a specific reverse primer set in singleplex qRT-PCR demonstrated the best quantitation and specificity in the detection of RNA from wildtype and mutant viruses. (C) 2013 Elsevier B.V. All rights reserved.
C1 [Worwa, Gabriella; Andrade, Christy C.; Thiemann, Tara C.; Park, Bborie; Reisen, William K.] Univ Calif Davis, Sch Vet Med, Dept Pathol Microbiol & Immunol, Ctr Vectorborne Dis, Davis, CA 95616 USA.
[Maharaj, Payal D.; Anishchenko, Michael; Brault, Aaron C.] Ctr Dis Control & Prevent, Div Vector Borne Dis, Ft Collins, CO 80521 USA.
RP Reisen, WK (reprint author), Univ Calif Davis, Sch Vet Med, Dept Pathol Microbiol & Immunol, Ctr Vectorborne Dis, Davis, CA 95616 USA.
EM wkreisen@ucdavis.edu
OI Maharaj, Payal/0000-0002-4157-4479
FU Swiss National Science Foundation (SNSF) [PBBEP3_128345]; Swiss
Foundation for Grants in Biology and Medicine (SFGBM) [PASMP3_137034/1];
National Institutes of Health (NIH) [T32 AI074550]; Pacific Southwest
Regional Center for Excellence (PSWRCE) [U54 AI065359]; Biomedical
Advanced Research and Development Authority (BARDA); National Institutes
of Allergy and Infectious Diseases (NIH) [RO1-AI55607]
FX The authors acknowledge Dr. Brent Ewing for providing an academic
license of PolySNP and PHRED. Special thanks to Dr. Gregory Ebel and Dr.
Gerod Hall for their advice on the implementation of the quantitative
sequencing. G. Worwa was supported by the Swiss National Science
Foundation (SNSF; PBBEP3_128345) and the Swiss Foundation for Grants in
Biology and Medicine (SFGBM; PASMP3_137034/1). C. Andrade was supported
by the National Institutes of Health training grant (NIH; T32 AI074550).
Funding for these studies was provided by the Pacific Southwest Regional
Center for Excellence (PSWRCE; U54 AI065359), Biomedical Advanced
Research and Development Authority (BARDA), and the National Institutes
of Allergy and Infectious Diseases (NIH; RO1-AI55607).
NR 18
TC 3
Z9 3
U1 0
U2 11
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0166-0934
EI 1879-0984
J9 J VIROL METHODS
JI J. Virol. Methods
PD JAN
PY 2014
VL 195
BP 76
EP 85
DI 10.1016/j.jviromet.2013.09.014
PG 10
WC Biochemical Research Methods; Biotechnology & Applied Microbiology;
Virology
SC Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology;
Virology
GA 277FQ
UT WOS:000328804800010
PM 24121135
ER
PT J
AU Welch, RJ
Chang, GJJ
Litwin, CM
AF Welch, Ryan J.
Chang, Gwong-Jen J.
Litwin, Christine M.
TI Comparison of a commercial dengue IgM capture ELISA with dengue antigen
focus reduction microneutralization test and the centers for disease
control dengue IgM capture-ELISA
SO JOURNAL OF VIROLOGICAL METHODS
LA English
DT Article
DE Dengue; Arbovirus; Microneutralization; ELISA; Antibodies; Flavivirus
ID LINKED IMMUNOSORBENT ASSAYS; IMMUNOGLOBULIN-M; INFECTION; DIAGNOSIS;
FEVER
AB Dengue (DENV) infection is caused by an arbovirus that is a member of the family Flaviviridae, genus Flavivirus. The diagnosis of acute dengue infection using clinical signs and symptoms can be difficult since the manifestations cannot be readily differentiated from other infections. Therefore the diagnosis of acute dengue infection depends upon laboratory assays. Dengue virus ELISAs have been designed for the detection of IgM and IgG antibodies in addition to nonstructural 1 (NS1) antigens. The InBios IgM Dengue ELISA was compared to the Antigen Focus Reduction Microneutralization Test (FR mu NT90) and Centers for Disease Control Dengue IgM Capture-ELISA (CDC MAC-ELISA). The calculated sensitivity, specificity and agreement of the InBios ELISA compared to FR mu NT90 and CDC MAC-ELISA was 88.7% (C.I. 81.4-93.7), 93.1% (C.I. 89.1-95.8) and 91.5% (C.I. 86.3-95.0), respectively.
In summary the InBios IgM Dengue ELISA sensitivity and specificity is comparable to other commercially available IgM Capture-ELISAs. (C) 2013 Elsevier B.V. All rights reserved.
C1 [Welch, Ryan J.; Litwin, Christine M.] Univ Utah, ARUP Inst Clin & Expt Pathol, Salt Lake City, UT USA.
[Chang, Gwong-Jen J.] US Dept Hlth & Human Serv, Publ Hlth Serv, Ctr Dis Control & Prevent, Arbovira1 Dis Branch,Div Vector Borne Dis, Ft Collins, CO USA.
[Litwin, Christine M.] Univ Utah, Dept Pathol, Salt Lake City, UT USA.
RP Litwin, CM (reprint author), Georgia Regents Univ, Med Coll Georgia, Dept Pathol, 1120 15th St, Augusta, GA 30912 USA.
EM clitwin@gru.edu
FU University of Utah, ARUP Institute for Clinical and Experimental
Pathology(R)
FX This study was supported by the University of Utah, ARUP Institute for
Clinical and Experimental Pathology (R).
NR 9
TC 6
Z9 6
U1 0
U2 7
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0166-0934
EI 1879-0984
J9 J VIROL METHODS
JI J. Virol. Methods
PD JAN
PY 2014
VL 195
BP 247
EP 249
DI 10.1016/j.jviromet.2013.10.019
PG 3
WC Biochemical Research Methods; Biotechnology & Applied Microbiology;
Virology
SC Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology;
Virology
GA 277FQ
UT WOS:000328804800035
PM 24161816
ER
PT J
AU Culzoni, MJ
Dwivedi, P
Green, MD
Newton, PN
Fernandez, FM
AF Culzoni, Maria J.
Dwivedi, Prabha
Green, Michael D.
Newton, Paul N.
Fernandez, Facundo M.
TI Ambient mass spectrometry technologies for the detection of falsified
drugs
SO MEDCHEMCOMM
LA English
DT Review
ID DESORPTION ELECTROSPRAY-IONIZATION; ATMOSPHERIC-PRESSURE
PHOTOIONIZATION; COUNTERFEIT ANTIMALARIAL TABLETS; INDUCED
CHEMICAL-IONIZATION; REAL-TIME; SURFACE SAMPLING/IONIZATION; SUBSTANDARD
MEDICINES; LIQUID-CHROMATOGRAPHY; SOLID-SURFACES; ION-SOURCE
AB Increased globalization of the pharmaceutical market has facilitated the unobstructed and fast spread of poor-quality medicines. Poor-quality medicines include spurious/falsely-labeled/falsified/counterfeit drugs (those that are deliberately and fraudulently mislabeled with respect to content and/or origin), substandard drugs (legitimate drugs that do not meet their quality specifications), and degraded medicines (good quality pharmaceuticals that suffered from deterioration caused by improper storage or distribution). Consumption of poor-quality pharmaceuticals is likely to increase morbidity and mortality. Moreover, poor-quality drugs can also contribute to the development of resistance to anti-infective medicines and decrease the quality of health care received by patients. To assess the true prevalence of poor quality drugs, tiered technology approaches enabling the testing of drug samples collected at points of sale are required, thus ensuring public health standards. High throughput and high resolution ambient mass spectrometry techniques allow investigation of pharmaceuticals with minimal or no sample preparation, thus possessing capabilities to survey a large number of drug samples for their authenticity.
C1 [Culzoni, Maria J.; Dwivedi, Prabha; Fernandez, Facundo M.] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA.
[Culzoni, Maria J.] Univ Nacl Litoral, Fac Bioquim & Ciencias Biol, Catedra Quim Analit 1, Lab Desarrollo Analit & Quimiometria LADAQ, Santa Fe, Argentina.
[Culzoni, Maria J.] Consejo Nacl Invest Cient & Tecn, RA-1033 Buenos Aires, DF, Argentina.
[Green, Michael D.] Ctr Dis Control & Prevent, Ctr Global Hlth, Div Parasit Dis & Malaria, Atlanta, GA USA.
[Newton, Paul N.] Mahosot Hosp, Microbiol Lab, Oxford Wellcome Trust Res Unit, Lao Oxford Mahosot Hospital Oxford, Viangchan, Lao PDR, Laos.
[Newton, Paul N.] Univ Oxford, Churchill Hosp, Ctr Trop Med, Nuffield Dept Med, Oxford, England.
[Newton, Paul N.] Univ Oxford, Churchill Hosp, WorldWide Antimalarial Resistance Network, Oxford, England.
RP Fernandez, FM (reprint author), Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA.
EM facundo.fernandez@chemistry.gatech.edu
FU Bill and Melinda Gates Foundation to the London School of Hygiene and
Tropical Medicine
FX The authors are grateful to the ACT consortium for funding their project
to assess the quality of drugs in Africa via an award from the Bill and
Melinda Gates Foundation to the London School of Hygiene and Tropical
Medicine.
NR 87
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U1 3
U2 45
PU ROYAL SOC CHEMISTRY
PI CAMBRIDGE
PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS,
ENGLAND
SN 2040-2503
EI 2040-2511
J9 MEDCHEMCOMM
JI MedChemComm
PY 2014
VL 5
IS 1
BP 9
EP 19
DI 10.1039/c3md00235g
PG 11
WC Biochemistry & Molecular Biology; Chemistry, Medicinal
SC Biochemistry & Molecular Biology; Pharmacology & Pharmacy
GA 278JH
UT WOS:000328886000001
ER
PT J
AU Schauer, GL
Malarcher, AM
Berg, CJ
AF Schauer, Gillian L.
Malarcher, Ann M.
Berg, Carla J.
TI Differences in Smoking and Cessation Characteristics Among Adult
Nondaily Smokers in the United States: Findings From the 20092010
National Adult Tobacco Survey
SO NICOTINE & TOBACCO RESEARCH
LA English
DT Article
ID INTERMITTENT SMOKING; CIGARETTE-SMOKING; HEALTH; LIGHT; PATTERNS
AB Nondaily smoking in the United States is increasing. Although differences in smoking and cessation behaviors between daily and nondaily smokers have been documented, differences among nondaily smokers are poorly understood. This study provides updated national data on smoking and cessation characteristics among nondaily versus daily smokers and between subgroups of nondaily smokers.
Data were obtained from the 20092010 National Adult Tobacco Survey, a stratified, dual-frame telephone survey conducted in the United States. Participants were categorized into daily smokers, never-daily nondaily smokers (NDNS), recently converted (1 year) nondaily smokers (RCNS), and established-converted (> 1 year) nondaily smokers (ECNS). Chi-square tests were used to assess differences across groups, and multivariable logistic regression was used to identify factors associated with past-year quit attempts.
Among nondaily smokers (17.8% of the total sample), 27.1% were NDNS, 37.4% were RCNS, and 35.4% were ECNS. RCNS were the most likely to report ever having tried to quit (p < .0001), having tried to quit in the past year (p < .0001), having used cessation treatment during their last quit attempt (p < .05), and wanting to quit smoking for good (p < .001). Compared with NDNS, RCNS had more than twice the odds of trying to quit in the past year after adjusting for demographics and smoking characteristics (adjusted odds ratio 2.1, 95% confidence interval 1.33.2). No significant differences existed between NDNS and ECNS.
RCNS are potentially more interested in quitting and should be specifically targeted with cessation interventions to avoid relapse to daily or long-term nondaily smoking.
C1 [Schauer, Gillian L.; Malarcher, Ann M.] Ctr Dis Control & Prevent, Off Smoking & Hlth, Atlanta, GA 30341 USA.
[Schauer, Gillian L.; Berg, Carla J.] Emory Univ, Atlanta, GA 30322 USA.
RP Schauer, GL (reprint author), Ctr Dis Control & Prevent, Off Smoking & Hlth, 4770 Buford Highway NE,Mailstop MS F-79, Atlanta, GA 30341 USA.
EM vyc9@cdc.gov
NR 28
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Z9 8
U1 0
U2 8
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1462-2203
EI 1469-994X
J9 NICOTINE TOB RES
JI Nicotine Tob. Res.
PD JAN
PY 2014
VL 16
IS 1
BP 58
EP 68
DI 10.1093/ntr/ntt113
PG 11
WC Substance Abuse; Public, Environmental & Occupational Health
SC Substance Abuse; Public, Environmental & Occupational Health
GA 280VT
UT WOS:000329059600008
PM 23925825
ER
PT J
AU Chaloupka, FJ
Kostova, D
Shang, C
AF Chaloupka, Frank J.
Kostova, Deliana
Shang, Ce
TI Cigarette Excise Tax Structure and Cigarette Prices: Evidence From the
Global Adult Tobacco Survey and the US National Adult Tobacco Survey
SO NICOTINE & TOBACCO RESEARCH
LA English
DT Article
AB Introduction: The importance of tobacco tax structure in determining the relative prices of different tobacco products and brands has become increasingly recognized. The structuring of tobacco tax across products and brands within a country can impact the variability of prices within a country, shaping consumption and influencing tobacco users' incentives to switch down to cheaper alternatives in response to tax and price increases.
Methods: Brand-specific data on the average prices paid for the top 5 cigarette brands in 13 countries were obtained from the Global Adult Tobacco Survey, and for the United States, data were obtained from the National Adult Tobacco Survey. The variability of cigarette prices paid across brands was analyzed in the context of each country's tobacco tax structure.
Results: Countries with simpler cigarette tax structures, particularly those that emphasize specific taxes and do not involve tier-based taxes, exhibit less variability in the prices smokers pay for cigarettes across brands.
Conclusions: Increases in cigarette taxes in countries with simpler tax structures will be more effective in reducing cigarette smoking and its health and economic consequences than comparable tax increases in countries where tax structures are more complicated and there are greater opportunities for switching to cheaper brands in order to avoid a tax increase.
C1 [Chaloupka, Frank J.] Univ Illinois, Dept Econ, Chicago, IL 60608 USA.
[Chaloupka, Frank J.; Shang, Ce] Univ Illinois, Inst Hlth Res & Policy, Chicago, IL 60608 USA.
[Kostova, Deliana] Ctr Dis Control & Prevent, Atlanta, GA USA.
RP Chaloupka, FJ (reprint author), Univ Illinois, Inst Hlth Res & Policy, 1747 W Roosevelt,Room 558, Chicago, IL 60608 USA.
EM fjc@uic.edu
RI Shang, Ce/L-3617-2016
FU Bloomberg Initiative to Reduce Tobacco Use, a program of Bloomberg
Philanthropies; Bill and Melinda Gates Foundation
FX Funding for the Global Adult Tobacco Survey (GATS) is provided by the
Bloomberg Initiative to Reduce Tobacco Use, a program of Bloomberg
Philanthropies. Governments of Brazil and India contributed to GATS
implementation in their respective countries. The Bill and Melinda Gates
Foundation provided additional funding for GATS implementation in China
and for analysis.
NR 24
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Z9 10
U1 1
U2 12
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1462-2203
EI 1469-994X
J9 NICOTINE TOB RES
JI Nicotine Tob. Res.
PD JAN
PY 2014
VL 16
SU 1
BP S3
EP S9
DI 10.1093/ntr/ntt121
PG 7
WC Substance Abuse; Public, Environmental & Occupational Health
SC Substance Abuse; Public, Environmental & Occupational Health
GA 282HP
UT WOS:000329161700002
PM 23935181
ER
PT J
AU Kostova, D
Chaloupka, FJ
Yurekli, A
Bettcher, D
Prasad, N
Asma, S
AF Kostova, Deliana
Chaloupka, Frank J.
Yurekli, Ayda
Bettcher, Douglas
Prasad, Neena
Asma, Samira
TI Nicotine and Tobacco Research Special Supplement: Economic Aspects of
Tobacco Use in Low- and Middle-Income Countries
SO NICOTINE & TOBACCO RESEARCH
LA English
DT Editorial Material
C1 [Kostova, Deliana; Asma, Samira] Ctr Dis Control & Prevent, Atlanta, GA 30341 USA.
[Chaloupka, Frank J.] Univ Illinois, Inst Hlth Res & Policy, Dept Econ & Hlth Policy, Chicago, IL USA.
[Yurekli, Ayda; Bettcher, Douglas] WHO, CH-1211 Geneva, Switzerland.
[Prasad, Neena] Bloomberg Initiat Reduce Tobacco Use, New York, NY USA.
RP Kostova, D (reprint author), Ctr Dis Control & Prevent, 4770 Buford Highway, Atlanta, GA 30341 USA.
EM kiv0@cdc.gov
NR 5
TC 0
Z9 0
U1 0
U2 1
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1462-2203
EI 1469-994X
J9 NICOTINE TOB RES
JI Nicotine Tob. Res.
PD JAN
PY 2014
VL 16
SU 1
BP S1
EP S2
DI 10.1093/ntr/ntt089
PG 2
WC Substance Abuse; Public, Environmental & Occupational Health
SC Substance Abuse; Public, Environmental & Occupational Health
GA 282HP
UT WOS:000329161700001
PM 24343954
ER
PT J
AU Kostova, D
Tesche, J
Perucic, AM
Yurekli, A
Asma, S
AF Kostova, Deliana
Tesche, Jean
Perucic, Anne-Marie
Yurekli, Ayda
Asma, Samira
CA GATS Collaborative Grp
TI Exploring the Relationship Between Cigarette Prices and Smoking Among
Adults: A Cross-Country Study of Low- and Middle-Income Nations
SO NICOTINE & TOBACCO RESEARCH
LA English
DT Article
ID TOBACCO USE
AB Evidence on the relationship between cigarette prices and adult smoking in low- and middle-income countries (LMICs) is relatively limited. This study offers new descriptive evidence on this relationship using data from a set of 13 LMICs.
We use Global Adult Tobacco Survey (GATS) cross-country data from approximately 200,000 participants aged 15 and older. Estimates on the relationship between prices and adult smoking were obtained from logit models of smoking participation and ordinary least squares models of conditional cigarette demand.
Higher prices were associated with lower demand across countries, in terms of both smoking prevalence and daily number of cigarettes smoked among smokers. Our estimates suggest that the total price elasticity of cigarette demand in LMICs is approximately 0.53. We find that higher socioeconomic status (SES), represented through wealth and education effects is associated with lower chance of smoking overall, but among existing smokers, it may be associated with a larger number of cigarettes smoked.
After controlling for a set of individual demographic and country characteristics, cigarette prices retain a significant role in shaping cigarette demand across LMICs. Because higher SES is associated with a reduced chance of smoking overall but also with increased daily consumption among current smokers, optimal tobacco tax policies in LMICs may face an added need to accommodate to shifting SES structures within the populations of these countries.
C1 [Kostova, Deliana; Tesche, Jean; Asma, Samira] Ctr Dis Control & Prevent, Atlanta, GA 30341 USA.
[Tesche, Jean] World Bank, Washington, DC 20433 USA.
[Perucic, Anne-Marie; Yurekli, Ayda] WHO, CH-1211 Geneva, Switzerland.
RP Kostova, D (reprint author), Ctr Dis Control & Prevent, 4770 Buford Highway, Atlanta, GA 30341 USA.
EM kiv0@cdc.gov
FU Bloomberg Initiative to Reduce Tobacco Use, a program of Bloomberg
Philanthropies; Bill and Melinda Gates Foundation
FX Funding for the Global Adult Tobacco Survey (GATS) is provided by the
Bloomberg Initiative to Reduce Tobacco Use, a program of Bloomberg
Philanthropies. Governments of Brazil and India contributed to GATS
implementation in their respective countries. Bill and Melinda Gates
Foundation provided additional funding for GATS implementation in China.
NR 27
TC 7
Z9 7
U1 0
U2 9
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1462-2203
EI 1469-994X
J9 NICOTINE TOB RES
JI Nicotine Tob. Res.
PD JAN
PY 2014
VL 16
SU 1
BP S10
EP S15
DI 10.1093/ntr/ntt170
PG 6
WC Substance Abuse; Public, Environmental & Occupational Health
SC Substance Abuse; Public, Environmental & Occupational Health
GA 282HP
UT WOS:000329161700003
PM 24343955
ER
PT J
AU Ross, H
Kostova, D
Stoklosa, M
Leon, M
AF Ross, Hana
Kostova, Deliana
Stoklosa, Michal
Leon, Maria
TI The Impact of Cigarette Excise Taxes on Smoking Cessation Rates From
1994 to 2010 in Poland, Russia, and Ukraine
SO NICOTINE & TOBACCO RESEARCH
LA English
DT Article
ID SOVIET-UNION; TOBACCO; INCREASES; DURATION; BEHAVIOR; PRICES; POLICY;
QUIT
AB We studied the impact of cigarette excise taxes on the rates of smoking cessation with data from 3 neighboring Eastern European countries (Russia, Poland, and Ukraine) during the post-transitional period of the 1990s and 2000s.
Using Global Adult Tobacco Survey data from 11,106 former and current smokers, we estimated the impact of cigarette taxes on the smokers likelihood of quitting over time. We first transformed the surveys cross-sectional data into a pseudo-longitudinal format in which the average observation period for individual subjects was 12 years and then employed duration analysis.
We estimated that a 10% increase in cigarette taxes during the observation period increased the probability of smoking cessation among smokers in these countries by 1.6% to 2.3%.
Cigarette tax increases have played a significant role in driving smoking cessation in Poland, Russia, and Ukraine. Further increases in cigarette excise taxes are likely to encourage further cessation and thus impact the prevalence of smoking in the region.
C1 [Ross, Hana; Stoklosa, Michal] Amer Canc Soc, Atlanta, GA 30303 USA.
[Kostova, Deliana] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Leon, Maria] Int Agcy Res Canc, F-69372 Lyon, France.
RP Ross, H (reprint author), Amer Canc Soc, 250 Williams St, Atlanta, GA 30303 USA.
EM hana.ross@cancer.org
FU European Commission (EC FP7) under the project Pricing Policies and
Control of Tobacco in Europe (PPACTE) [HEALTH-F2-2009-223323]; Bloomberg
Initiative to Reduce Tobacco Use, a program of Bloomberg Philanthropies
FX This work was supported by the European Commission (EC FP7) under the
project Pricing Policies and Control of Tobacco in Europe (PPACTE)
(HEALTH-F2-2009-223323). Funding for the Global Adult Tobacco Survey
(GATS) is provided by the Bloomberg Initiative to Reduce Tobacco Use, a
program of Bloomberg Philanthropies.
NR 35
TC 4
Z9 5
U1 1
U2 4
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1462-2203
EI 1469-994X
J9 NICOTINE TOB RES
JI Nicotine Tob. Res.
PD JAN
PY 2014
VL 16
SU 1
BP S37
EP S43
DI 10.1093/ntr/ntt024
PG 7
WC Substance Abuse; Public, Environmental & Occupational Health
SC Substance Abuse; Public, Environmental & Occupational Health
GA 282HP
UT WOS:000329161700007
PM 24343956
ER
PT J
AU Shang, C
Chaloupka, FJ
Kostova, D
AF Shang, Ce
Chaloupka, Frank J.
Kostova, Deliana
TI Who Quits? An Overview of Quitters in Low- and Middle-Income Countries
SO NICOTINE & TOBACCO RESEARCH
LA English
DT Article
ID SMOKING-CESSATION; CIGARETTE AFFORDABILITY; UNITED-STATES; YOUNG-ADULTS;
SMOKERS; INTENTION; YOUTH
AB Using the Global Adult Tobacco Surveys from 14 primarily low- and middle-income countries, we describe the association between the probability of being a recent quitter and a number of demographic and policy-relevant factors such as exposure to warning labels, work-site smoking bans, antismoking media messaging, tobacco marketing, and current cigarette and bidi prices.
Logistic regressions were used to examine the potential correlates of recent quitting and recent quit attempts.
After accounting for country-specific attributes in pooled analyses, we found that higher rates of exposure to work-site smoking bans are associated with higher odds of being a quitter (odds ratio [OR] with 95% confidence interval [CI] 1.13 [1.04, 1.22]). Exposure to antismoking media messaging (OR with 95% CI 1.08 [1.00, 1.17]), work-site smoking bans (OR with 95% CI 1.11 [0.99, 1.26]), and warning labels (OR with 95% CI 1.03 [1.01, 1.05]); cigarette prices (OR with 95% CI 1.01 [1.00, 1.02]), and bidi prices (OR with 95% CI 1.17 [1.11, 1.22]) are factors associated with higher odds of recent quit attempts in the pooled analysis. These effects vary by country. Exposure to warning labels is found to be associated with greater likelihood of recent quitting in Egypt (OR with 95% CI 3.20 [1.53, 6.68]), and the positive association between exposure to work-site smoking bans and quitting is particularly strong for Southeast Asia (OR with 95% CI 1.20 [1.06, 1.35]) and Asia Pacific countries (OR with 95% CI 1.85 [0.93, 3.68]). Additionally, exposure to tobacco industry marketing is significantly associated with smaller odds of quitting in Asia Pacific (OR with 95% CI 0.83 [0.79, 0.87]) and Latin American countries (OR with 95% CI 0.78 [0.74, 0.82]).
Although our results vary by country, they generally suggest that greater exposure to tobacco control polices is significantly associated with quitting.
C1 [Shang, Ce; Chaloupka, Frank J.] Univ Illinois, Ctr Hlth Policy, Inst Hlth Res & Policy, Chicago, IL 60608 USA.
[Chaloupka, Frank J.] Univ Illinois, Dept Econ, Chicago, IL 60608 USA.
[Kostova, Deliana] Ctr Dis Control & Prevent, Atlanta, GA USA.
RP Shang, C (reprint author), Univ Illinois, Ctr Hlth Policy, Inst Hlth Res & Policy, Room 422,1747 W Roosevelt Rd, Chicago, IL 60608 USA.
EM cshang@uic.edu
RI Shang, Ce/L-3617-2016
FU Bloomberg Initiative to Reduce Tobacco Use, a program of Bloomberg
Philanthropies; Bill and Melinda Gates Foundation
FX Funding for the Global Adult Tobacco Survey (GATS) is provided by the
Bloomberg Initiative to Reduce Tobacco Use, a program of Bloomberg
Philanthropies. Governments of Brazil and India contributed to GATS
implementation in their respective countries. The Bill and Melinda Gates
Foundation provided additional funding for GATS implementation in China
and for analysis.
NR 26
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U1 0
U2 5
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1462-2203
EI 1469-994X
J9 NICOTINE TOB RES
JI Nicotine Tob. Res.
PD JAN
PY 2014
VL 16
SU 1
BP S44
EP S55
DI 10.1093/ntr/ntt179
PG 12
WC Substance Abuse; Public, Environmental & Occupational Health
SC Substance Abuse; Public, Environmental & Occupational Health
GA 282HP
UT WOS:000329161700008
PM 24343957
ER
PT J
AU Barradas, DT
Dietz, PM
Pearl, M
England, LJ
Callaghan, WM
Kharrazi, M
AF Barradas, Danielle T.
Dietz, Patricia M.
Pearl, Michelle
England, Lucinda J.
Callaghan, William M.
Kharrazi, Martin
TI Validation of Obstetric Estimate Using Early Ultrasound: 2007 California
Birth Certificates
SO PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
LA English
DT Article
DE validity; gestational age; preterm
ID GESTATIONAL-AGE; FETAL AGE; BIOMETRY
AB BackgroundObstetric estimate (OE) of gestational age, recently added to the standard US birth certificate, has not been validated. Using early ultrasound-based gestational age (prior to 20 weeks gestation) as the criterion standard, we estimated the prevalence of preterm delivery and the sensitivity and positive predictive value (PPV) of gestational age estimates based on OE.
MethodsWe analyzed 165148 singleton livebirth records (38% of California livebirths during the study period) with linked early ultrasound information from a statewide California prenatal screening programme. OE of gestational age estimates was obtained from birth certificates.
ResultsPrevalence of preterm delivery (<37 weeks gestation) was higher based on early ultrasound (8.1%) compared with preterm delivery based on OE (7.1%). Sensitivity for preterm birth when using OE for gestational age was 74.9% (95% confidence interval [CI] [74.1, 75.6]), and PPV was 85.1% (95% CI [84.4, 85.7]). Incongruence, defined as a14-day difference between early-ultrasound-derived gestational age and OE, was 3.4%.
ConclusionsOE reported on the birth certificate may underestimate the prevalence of preterm delivery, particularly among women of non-Hispanic non-white race and ethnicity and women with lower educational attainment, public insurance at time of delivery, and missing prepregnancy BMI. Additional validation studies in other samples of births are needed.
C1 [Barradas, Danielle T.; Dietz, Patricia M.; England, Lucinda J.; Callaghan, William M.] Ctr Dis Control & Prevent, Div Reprod Hlth, Atlanta, GA 30341 USA.
[Pearl, Michelle] Sequoia Fdn, Richmond, CA USA.
[Kharrazi, Martin] Calif Dept Publ Hlth, Genet Dis Screening Program, Richmond, CA USA.
RP Barradas, DT (reprint author), Ctr Dis Control & Prevent, Div Reprod Hlth, 4770 Buford Hwy NE,MS K-22, Atlanta, GA 30341 USA.
EM dbarradas@cdc.gov
FU Intramural CDC HHS [CC999999]; NIDDK NIH HHS [T32 DK007734]
NR 13
TC 6
Z9 6
U1 0
U2 2
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0269-5022
EI 1365-3016
J9 PAEDIATR PERINAT EP
JI Paediatr. Perinat. Epidemiol.
PD JAN
PY 2014
VL 28
IS 1
BP 3
EP 10
DI 10.1111/ppe.12083
PG 8
WC Public, Environmental & Occupational Health; Obstetrics & Gynecology;
Pediatrics
SC Public, Environmental & Occupational Health; Obstetrics & Gynecology;
Pediatrics
GA 264RX
UT WOS:000327899300002
PM 24117928
ER
PT J
AU Adgent, MA
Hoffman, K
Goldman, BD
Sjodin, A
Daniels, JL
AF Adgent, Margaret A.
Hoffman, Kate
Goldman, Barbara Davis
Sjoedin, Andreas
Daniels, Julie L.
TI Brominated Flame Retardants in Breast Milk and Behavioural and Cognitive
Development at 36 Months
SO PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
LA English
DT Article
DE PBDEs; halogenated diphenyl ethers; flame retardants; milk; human;
environment; environmental pollutant; epidemiology; neurobehavioural
manifestations
ID POLYBROMINATED DIPHENYL ETHERS; ACUTE POSTNATAL EXPOSURE; NEONATAL
EXPOSURE; MARKET-BASKET; ENVIRONMENT; PBDES; RATS; RECEPTORS; ATTENTION;
INFANTS
AB BackgroundPolybrominated diphenyl ethers (PBDEs) are persistent flame retardants found in the environment, in household dust, and in humans. Breast feeding is a prominent route of exposure in infancy. PBDEs adversely affect neurodevelopment in animals. Here, we estimate associations between PBDEs in breast milk and behaviour and cognitive skills in children at 36 months of age.
MethodsWe prospectively studied 304 mothers and their children. We measured PBDEs in breast milk collected at 3 months postpartum. At 36 months, we measured child behaviour with the parent-rated Behavioral Assessment System for Children 2 (n=192), and cognitive skills with the Mullen Scales of Early Learning (n=184). We analysed data with robust regression.
ResultsWe detected BDE-28, -47, -99, -100, and -153 in >70% of milk samples. For each congener, the highest quartile of breast milk PBDE concentration, vs. the lowest, was associated with more anxious behaviour, after confounder adjustment. Select congeners were associated with increased withdrawal (BDE-28) and improved activity of daily living skills (BDE-153). Cognitive skills tended to be positively associated with PBDEs, especially language and fine motor skills. However, most estimates were imprecise.
ConclusionsHere, lactational PBDE exposure was modestly and imprecisely associated with anxiety and withdrawal, but was also associated with improved adaptive and cognitive skills. Positive factors associated with breast feeding may have mitigated some of the hypothesised adverse neurodevelopmental outcomes associated with PBDEs. Further research is needed to inform our understanding of PBDE neurotoxicity and how sources of exposure might confound neurodevelopmental studies.
C1 [Adgent, Margaret A.] NIEHS, Res Triangle Pk, NC 27709 USA.
[Hoffman, Kate; Daniels, Julie L.] Univ N Carolina, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27599 USA.
[Goldman, Barbara Davis] Univ N Carolina, Frank Porter Graham Child Dev Inst, Chapel Hill, NC 27599 USA.
[Goldman, Barbara Davis] Univ N Carolina, Dept Psychol, Chapel Hill, NC 27599 USA.
[Sjoedin, Andreas] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Div Sci Lab, Atlanta, GA USA.
RP Daniels, JL (reprint author), Univ N Carolina, Dept Epidemiol, CB 7435, Chapel Hill, NC 27599 USA.
EM julie_daniels@unc.edu
RI Sjodin, Andreas/F-2464-2010
FU Environmental Protection Agency [RD832736]; National Institute of
Environmental Health Sciences (NIEHS) [P30ES10126]; Centers for Disease
Control and Prevention Foundation; NIEHS Environmental Biostatistics
Training Program [T32ES007018]; Intramural Research Program of the NIH,
National Institute of Environmental Health Sciences
FX This research was supported in part by grants from the Environmental
Protection Agency (RD832736), the National Institute of Environmental
Health Sciences (NIEHS) (P30ES10126), and the Centers for Disease
Control and Prevention Foundation. The work of Kate Hoffman was
supported by the NIEHS Environmental Biostatistics Training Program
(T32ES007018). This research was supported [in part] by the Intramural
Research Program of the NIH, National Institute of Environmental Health
Sciences. The authors have no financial relationships relevant to this
article or conflicts of interest to disclose.
NR 41
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Z9 11
U1 4
U2 39
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0269-5022
EI 1365-3016
J9 PAEDIATR PERINAT EP
JI Paediatr. Perinat. Epidemiol.
PD JAN
PY 2014
VL 28
IS 1
BP 48
EP 57
DI 10.1111/ppe.12078
PG 10
WC Public, Environmental & Occupational Health; Obstetrics & Gynecology;
Pediatrics
SC Public, Environmental & Occupational Health; Obstetrics & Gynecology;
Pediatrics
GA 264RX
UT WOS:000327899300007
PM 24313667
ER
PT J
AU Feldkamp, ML
Srisukhumbowornchai, S
Romitti, PA
Olney, RS
Richardson, SD
Botto, LD
AF Feldkamp, Marcia L.
Srisukhumbowornchai, Sivithee
Romitti, Paul A.
Olney, Richard S.
Richardson, Sandra D.
Botto, Lorenzo D.
CA Natl Birth Defects Prevention
TI Self-Reported Maternal Cigarette Smoke Exposure during the
Periconceptional Period and the Risk for Omphalocoele
SO PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
LA English
DT Article
DE cigarette smoke; maternal smoking; omphalocoele; second-hand smoke
ID BIRTH-DEFECTS PREVENTION; TOBACCO-SMOKE; OROFACIAL CLEFTS; CONSUMPTION;
PREGNANCY
AB BackgroundWe investigated whether maternal exposure to cigarette smoke was associated with omphalocoele and whether periconceptional folic acid modified the association.
Methods:We analysed data from the National Birth Defects Prevention Study on omphalocoele case (n=301) and control (n=8135) mothers for infants born from 1997 through 2007. Mothers who reported active smoking or exposure to second-hand smoke during the periconceptional period (1 month before conception to 3 months after) were considered exposed. Those who reported use of folic acid supplements during the same period were considered supplement users. Odds ratios and 95% confidence intervals were estimated using multivariable logistic regression adjusted for alcohol use, preconception body mass index, and race/ethnicity.
ResultsOne hundred fifteen (38.2%) case and 2592 (31.9%) control mothers reported exposure to cigarette smoke during the periconceptional period. Adjusted odds ratios [95% confidence intervals] were 1.19 [0.94, 1.53] for any smoke exposure, 0.87 [0.54, 1.40] for active smoking, 1.38 [1.00, 1.90] for second-hand smoke exposure, and 1.16 [0.80, 1.67] for both exposures combined. No dose-response relationship was observed. Folic acid-containing supplements did not reduce the risk for omphalocoele among women with active or second-hand smoke exposure.
ConclusionsSelf-reported active maternal smoking, with or without exposure to second-hand smoke, during the periconceptional period was not associated with omphalocoele. In contrast, there was a possible association with periconceptional exposure to second-hand smoke.
C1 [Feldkamp, Marcia L.; Srisukhumbowornchai, Sivithee; Botto, Lorenzo D.] Univ Utah, Dept Pediat, Salt Lake City, UT 84132 USA.
[Romitti, Paul A.] Univ Iowa, Coll Publ Hlth, Iowa City, IA USA.
[Olney, Richard S.] CDC, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USA.
[Richardson, Sandra D.] New York State Dept Hlth, Albany, NY USA.
RP Feldkamp, ML (reprint author), Univ Utah, Hlth Sci Ctr, Dept Pediat, Div Med Genet, 2C 412 SOM,50 North Mario Capecchi Dr, Salt Lake City, UT 84132 USA.
EM marcia.feldkamp@hsc.utah.edu
FU CDC [PA 96043, PA 02081, FOA DD09-001]
FX This work was supported through cooperative agreements under PA 96043,
PA 02081, and FOA DD09-001 from the CDC to the Centers for Birth Defects
Research and Prevention participating in the National Birth Defects
Prevention Study.
NR 33
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U1 1
U2 2
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0269-5022
EI 1365-3016
J9 PAEDIATR PERINAT EP
JI Paediatr. Perinat. Epidemiol.
PD JAN
PY 2014
VL 28
IS 1
BP 67
EP 73
DI 10.1111/ppe.12093
PG 7
WC Public, Environmental & Occupational Health; Obstetrics & Gynecology;
Pediatrics
SC Public, Environmental & Occupational Health; Obstetrics & Gynecology;
Pediatrics
GA 264RX
UT WOS:000327899300009
PM 24313669
ER
PT J
AU Philipp, CS
Faiz, AS
Beckman, MG
Grant, A
Bockenstedt, PL
Heit, JA
James, AH
Kulkarni, R
Manco-Johnson, MJ
Moll, S
Ortel, TL
AF Philipp, Claire S.
Faiz, Ambarina S.
Beckman, Michele G.
Grant, Althea
Bockenstedt, Paula L.
Heit, John A.
James, Andra H.
Kulkarni, Roshni
Manco-Johnson, Marilyn J.
Moll, Stephan
Ortel, Thomas L.
TI Differences in Thrombotic Risk Factors in Black and White Women with
Adverse Pregnancy Outcome
SO THROMBOSIS RESEARCH
LA English
DT Article
DE Thrombotic risk factors; thrombophilia; adverse pregnancy outcomes;
racial disparities
ID FACTOR-V-LEIDEN; FETAL LOSS; ANTIPHOSPHOLIPID SYNDROME; THROMBOPHILIC
DISORDERS; VENOUS THROMBOEMBOLISM; COMPLICATIONS; MISCARRIAGE;
MORTALITY; MUTATION; COHORT
AB Introduction: Black women have an increased risk of adverse pregnancy outcomes and the characteristics of thrombotic risk factors in this population are unknown. The objective of this study was to examine the racial differences in thrombotic risk factors among women with adverse pregnancy outcomes.
Methods: Uniform data were collected in women with adverse pregnancy outcomes (pregnancy losses, intrauterine growth restriction (IUGR), prematurity, placental abruption and preeclampsia) referred to Thrombosis Network Centers funded by the Centers for Disease Control and Prevention (CDC).
Results: Among 343 white and 66 black women seen for adverse pregnancy outcomes, protein S and antithrombin deficiencies were more common in black women. The prevalence of diagnosed thrombophilia was higher among whites compared to blacks largely due to Factor V Leiden mutation. The prevalence of a personal history of venous thromboembolism (VTE) did not differ significantly by race. A family history of VTE, thrombophilia, and stroke or myocardial infarction (MI) was higher among whites. Black women had a higher body mass index, and a higher prevalence of hypertension, while the prevalence of sickle cell disease was approximately 27 fold higher compared to the general US black population.
Conclusions: Thrombotic risk factors differ significantly in white and black women with adverse pregnancy outcomes. Such differences highlight the importance of considering race separately when assessing thrombotic risk factors for adverse pregnancy outcomes. (C) 2013 Elsevier Ltd. All rights reserved.
C1 [Philipp, Claire S.; Faiz, Ambarina S.] Rutgers Robert Wood Johnson Med Sch, Dept Med, New Brunswick, NJ 08903 USA.
[Beckman, Michele G.; Grant, Althea] Ctr Dis Control & Prevent, Div Blood Disorders, Atlanta, GA USA.
[Bockenstedt, Paula L.] Univ Michigan, Dept Med, Ann Arbor, MI 48109 USA.
[Heit, John A.] Mayo Clin, Div Cardiovasc Dis, Rochester, MN USA.
[James, Andra H.] Duke Univ, Dept Obstet & Gynecol, Durham, NC USA.
[Kulkarni, Roshni] Michigan State Univ, Dept Pediat & Human Dev, E Lansing, MI 48824 USA.
[Manco-Johnson, Marilyn J.] Univ Colorado, Dept Pediat, Denver, CO 80202 USA.
[Manco-Johnson, Marilyn J.] Childrens Hosp, Aurora, CO USA.
[Moll, Stephan] Univ N Carolina, Dept Med, Chapel Hill, NC USA.
[Ortel, Thomas L.] Duke Univ, Dept Pathol & Med, Durham, NC USA.
RP Philipp, CS (reprint author), Rutgers Robert Wood Johnson Med Sch, Div Hematol, MEB Rm 378, New Brunswick, NJ 08903 USA.
EM philipp@rutgers.edu
FU Centers for Disease Control and Prevention [DD000017, DD000235,
DD000016, DD000292, DD000014, DD000015]
FX This work was supported by grants from the Centers for Disease Control
and Prevention (DD000017 to CP, DD000235 to JAH, DD000016 to MMJ,
DD000292 to SM, DD000014 to TLO, and DD000015 to the Hemophilia
Foundation of Michigan [PLB, RK]).
NR 29
TC 4
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U1 1
U2 2
PU PERGAMON-ELSEVIER SCIENCE LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
SN 0049-3848
J9 THROMB RES
JI Thromb. Res.
PD JAN
PY 2014
VL 133
IS 1
BP 108
EP 111
DI 10.1016/j.thromres.2013.10.035
PG 4
WC Hematology; Peripheral Vascular Disease
SC Hematology; Cardiovascular System & Cardiology
GA 278TF
UT WOS:000328911900019
PM 24246297
ER
PT J
AU Levin, ML
Zemtsova, GE
Montgomery, M
Killmaster, LF
AF Levin, M. L.
Zemtsova, G. E.
Montgomery, M.
Killmaster, L. F.
TI Effects of homologous and heterologous immunization on the reservoir
competence of domestic dogs for Rickettsia conorii (israelensis)
SO TICKS AND TICK-BORNE DISEASES
LA English
DT Article
DE Rickettsia conorii; Immunization; Reservoir competence; Horizontal
transmission; Rhipicephalus sanguineus
ID SPOTTED-FEVER GROUP; RHIPICEPHALUS-SANGUINEUS TICKS;
DERMACENTOR-VARIABILIS TICK; MOLECULAR-DETECTION; CROSS-PROTECTION;
NATURAL-HISTORY; SP-NOV; MASSILIAE; INFECTION; SUSCEPTIBILITY
AB A number of spotted fever group (SFG) rickettsiae cause serious infections in humans. Several antigenically related rickettsial agents may coexist within the same geographical area, and humans or vertebrate hosts may be sequentially exposed to multiple SFG agents. We assessed whether exposure of a vertebrate reservoir to one SFG Rickettsia will affect the host's immune response to a related pathogen and the efficiency of transmission to uninfected ticks. Two pairs of dogs were each infected with either Rickettsia massiliae or Rickettsia conorii israelensis, and their immune response was monitored twice weekly by IFA. The four immunized dogs and a pair of naive dogs were each challenged with R. conorii israelensis-infected Rhipicephalus sanguineus nymphs. Uninfected Rh. sanguineus larvae were acquisition-fed on the dogs on days 1, 7, and 14 post-challenge. These ticks were tested for the presence of rickettsial DNA after molting to the nymphal stage. The naive dogs became infected with R. conorii israelensis and were infectious to ticks for at least 3 weeks, whereas reservoir competence of dogs previously infected with either R. massiliae or R. conorii was significantly diminished. This opens an opportunity for decreasing the efficiency of transmission and propagation of pathogenic Rickettsia in natural foci by immunizing the primary hosts with closely related nonpathogenic SFG bacteria. However, neither homologous immunization nor cross-immunization significantly affected the efficiency of R. conorii transmission between cofeeding infected nymphs and uninfected larvae. At high densities of ticks, the efficiency of cofeeding transmission may be sufficient for yearly amplification and persistent circulation of a rickettsial pathogen in the vector population. Published by Elsevier GmbH.
C1 [Levin, M. L.; Zemtsova, G. E.; Montgomery, M.; Killmaster, L. F.] Ctr Dis Control & Prevent, Rickettsial Zoonoses Branch, Atlanta, GA 30333 USA.
RP Levin, ML (reprint author), Ctr Dis Control & Prevent, Rickettsial Zoonoses Branch, 1600 Clifton Rd,MS G-13, Atlanta, GA 30333 USA.
EM MLevin@cdc.gov
NR 58
TC 5
Z9 5
U1 0
U2 2
PU ELSEVIER GMBH, URBAN & FISCHER VERLAG
PI JENA
PA OFFICE JENA, P O BOX 100537, 07705 JENA, GERMANY
SN 1877-959X
EI 1877-9603
J9 TICKS TICK-BORNE DIS
JI Ticks Tick-Borne Dis.
PY 2014
VL 5
IS 1
BP 33
EP 40
DI 10.1016/j.ttbdis.2013.07.010
PG 8
WC Infectious Diseases; Microbiology; Parasitology
SC Infectious Diseases; Microbiology; Parasitology
GA 280CW
UT WOS:000329007300006
PM 24201056
ER
PT J
AU Kostova, D
Chaloupka, FJ
Yurekli, A
Ross, H
Cherukupalli, R
Andes, L
Asma, S
AF Kostova, Deliana
Chaloupka, Frank J.
Yurekli, Ayda
Ross, Hana
Cherukupalli, Rajeev
Andes, Linda
Asma, Samira
CA GATS Collaborative Grp
TI A cross-country study of cigarette prices and affordability: evidence
from the Global Adult Tobacco Survey
SO TOBACCO CONTROL
LA English
DT Article
ID SMOKING
AB Objective To describe the characteristics of two primary determinants of cigarette consumption: cigarette affordability and the range of prices paid for cigarettes (and bidis, where applicable) in a set of 15 countries. From this cross-country comparison, identify places where opportunities may exist for reducing consumption through tax adjustments.
Data Self-response data from 45,838 smokers from 15 countries, obtained from the Global Adult Tobacco Survey (GATS) 2008-2011.
Design Using self-response data on individual cigarette expenditure and consumption, we construct a measure of the average cigarette price smokers pay for manufactured cigarettes (and bidis, where applicable) in 15 countries. We use these prices to evaluate cigarette affordability and the range of prices available in each country. These survey-derived measures of cigarette price and affordability are uniquely suited for cross-country comparison because they represent each country's distinctive mix of individual consumption characteristics such as brand choice, intensity of consumption, and purchasing behavior.
Results In this sample of countries, cigarettes are most affordable in Russia, which has the most room for tobacco tax increase. Affordability is also relatively high in Brazil and China for cigarettes, and in India and Bangladesh for bidis. Although the affordability of cigarettes in India is relatively low, the range of cigarette prices paid is relatively high, providing additional evidence to support the call for simplifying the existing tax structure and reducing the width of price options. China has both high affordability and wide price ranges, suggesting multiple opportunities for reducing consumption through tax adjustments.
C1 [Kostova, Deliana; Andes, Linda; Asma, Samira] Ctr Dis Control & Prevent, Atlanta, GA 30341 USA.
[Chaloupka, Frank J.] Univ Illinois, Ctr Hlth Policy, Chicago, IL USA.
[Yurekli, Ayda] World Hlth Org, Geneva, Switzerland.
[Ross, Hana] Amer Canc Soc, Atlanta, GA 30329 USA.
[Cherukupalli, Rajeev] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Baltimore, MD USA.
RP Kostova, D (reprint author), Ctr Dis Control & Prevent, 4770 Buford Hwy,MS F16, Atlanta, GA 30341 USA.
EM kiv0@cdc.gov
NR 17
TC 12
Z9 12
U1 2
U2 6
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 0964-4563
EI 1468-3318
J9 TOB CONTROL
JI Tob. Control
PD JAN
PY 2014
VL 23
IS 1
AR e3
DI 10.1136/tobaccocontrol-2011-050413
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 273QJ
UT WOS:000328550800004
PM 22923477
ER
PT J
AU Rider, CV
Boekelheide, K
Catlin, N
Gordon, CJ
Morata, T
Selgrade, MK
Sexton, K
Simmons, JE
AF Rider, Cynthia V.
Boekelheide, Kim
Catlin, Natasha
Gordon, Christopher J.
Morata, Thais
Selgrade, MaryJane K.
Sexton, Kenneth
Simmons, Jane Ellen
TI Cumulative Risk: Toxicity and Interactions of Physical and Chemical
Stressors
SO TOXICOLOGICAL SCIENCES
LA English
DT Article
DE cumulative risk; nonchemical stressors; joint action; radiation;
infectious disease; sunlight; temperature; noise
ID INDUCED HEARING-LOSS; GERM-CELL APOPTOSIS; CARBON-MONOXIDE;
CYTOMEGALOVIRUS-INFECTION; INCREASED SUSCEPTIBILITY; INFLAMMATORY
RESPONSES; INFLUENZA INFECTION; INDUCED HYPOTHERMIA; NOISE ANNOYANCE;
EXPOSURE
AB Recent efforts to update cumulative risk assessment procedures to incorporate nonchemical stressors ranging from physical to psychosocial reflect increased interest in consideration of the totality of variables affecting human health and the growing desire to develop community-based risk assessment methods. A key roadblock is the uncertainty as to how nonchemical stressors behave in relationship to chemical stressors. Physical stressors offer a reasonable starting place for measuring the effects of nonchemical stressors and their modulation of chemical effects (and vice versa), as they clearly differ from chemical stressors; and doses of many physical stressors are more easily quantifiable than those of psychosocial stressors. There is a commonly held belief that virtually nothing is known about the impact of nonchemical stressors on chemically mediated toxicity or the joint impact of coexposure to chemical and nonchemical stressors. Although this is generally true, there are several instances where a substantial body of evidence exists. A workshop titled Cumulative Risk: Toxicity and Interactions of Physical and Chemical Stressors held at the 2013 Society of Toxicology Annual Meeting provided a forum for discussion of research addressing the toxicity of physical stressors and what is known about their interactions with chemical stressors, both in terms of exposure and effects. Physical stressors including sunlight, heat, radiation, infectious disease, and noise were discussed in reference to identifying pathways of interaction with chemical stressors, data gaps, and suggestions for future incorporation into cumulative risk assessments.
C1 [Rider, Cynthia V.] NIEHS, Div Natl Toxicol Program, Res Triangle Pk, NC 27709 USA.
[Boekelheide, Kim; Catlin, Natasha] Brown Univ, Providence, RI 02912 USA.
[Gordon, Christopher J.] US EPA, Effects Res Lab, Off Res & Dev, Res Triangle Pk, NC 27711 USA.
[Morata, Thais] NIOSH, Integrated Syst Toxicol Div, Cincinnati, OH 45226 USA.
[Selgrade, MaryJane K.] ICF Int, Durham, NC 27713 USA.
[Sexton, Kenneth] Univ N Carolina, Dept Environm Sci & Engn, Chapel Hill, NC 27599 USA.
[Simmons, Jane Ellen] US EPA, Integrated Syst Toxicol Div, Natl Hlth & Environm Effects Res Lab, Off Res & Dev, Res Triangle Pk, NC 27709 USA.
RP Rider, CV (reprint author), NIEHS, 111 TW Alexander Dr,POB 12233,MD K2-12, Res Triangle Pk, NC 27709 USA.
EM ridercv@niehs.nih.gov
FU Superfund Research Program grant [P42ES013660]; Training grant
[T32ES07272]; National Institute of Health, National Institute of
Environmental Health Sciences
FX Superfund Research Program grant (P42ES013660 to K. B.); Training grant
(NC; T32ES07272); the Intramural Research Program of the National
Institute of Health, National Institute of Environmental Health
Sciences.
NR 54
TC 6
Z9 6
U1 3
U2 21
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1096-6080
EI 1096-0929
J9 TOXICOL SCI
JI Toxicol. Sci.
PD JAN
PY 2014
VL 137
IS 1
BP 3
EP 11
DI 10.1093/toxsci/kft228
PG 9
WC Toxicology
SC Toxicology
GA 281XD
UT WOS:000329133400002
PM 24154487
ER
PT J
AU Feelemyer, J
Des Jarlais, D
Arasteh, K
Abdul-Quader, AS
Hagan, H
AF Feelemyer, Jonathan
Des Jarlais, Don
Arasteh, Kamyar
Abdul-Quader, Abu S.
Hagan, Holly
TI Retention of participants in medication-assisted programs in low- and
middle-income countries: an international systematic review
SO ADDICTION
LA English
DT Review
DE Buprenorphine; developing countries; low- and middle-income countries;
methadone; opiate abuse; opiate substitution programs
ID METHADONE-MAINTENANCE TREATMENT; INJECTION-DRUG USERS; QUALITY-OF-LIFE;
TRADITIONAL CHINESE MEDICINE; CONTROLLED-TRIAL; BUPRENORPHINE
MAINTENANCE; SUBSTITUTION THERAPY; HEROIN DEPENDENCE; OPIOID DEPENDENCE;
SUBSTANCE USE
AB Background and aimsMedication-assisted treatment (MAT) is a key component in overdose prevention, reducing illicit opiate use and risk of blood-borne virus infection. By retaining participants in MAT programs for longer periods of time, more noticeable and permanent changes in drug use, risk behavior and quality of life can be achieved. Many studies have documented retention in MAT programs in high-income countries, using a 50% average 12-month follow-up retention rate as a marker for a successful MAT program. This study contributes to a systematic understanding of how successful programs have been in retaining participants in low- and middle-income countries (LMIC) over time.
MethodsUsing Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we conducted a systematic literature search to identify MAT program studies that documented changes in retention over time for participants in buprenorphine and methadone programs in LMIC. Retention was measured for participants by length of follow-up, type of MAT and treatment dosage.
ResultsThere were 58 MAT program studies, with 27047 participants eligible for inclusion in the review. Overall average retention after 12 months was 54.3% [95% confidence interval (CI)=46.2, 63.7%]. Overall average retention was moderately good for both buprenorphine (48.3%, 95% CI=22.1, 74.6%) and methadone (56.6%, 95% CI=45.9%, 67.3%) after 12 months of treatment. Among programs using methadone there was no statistically significant difference in average retention by dosage level, and the 10 highest and lowest dosage programs obtained similar average retention levels after 12 months.
ConclusionMedication-assisted treatment programs in low- and middle-income countries achieve an average 50% retention rate after 12 months, with wide variation across programs but little difference between those using buprenorphine versus methadone.
C1 [Feelemyer, Jonathan; Des Jarlais, Don; Arasteh, Kamyar] Beth Israel Deaconess Med Ctr, Baron Edmond Rothschild Chem Dependency Inst, New York, NY 10038 USA.
[Abdul-Quader, Abu S.] Ctr Dis Control & Prevent, Global AIDS Program, Atlanta, GA USA.
[Hagan, Holly] NYU, Coll Nursing, New York, NY USA.
RP Feelemyer, J (reprint author), Beth Israel Deaconess Med Ctr, Baron Edmond Rothschild Chem Dependency Inst, 160 Water St,FL 24, New York, NY 10038 USA.
EM jfeelemyer@chpnet.org
FU NIAID NIH HHS [R01 AI083035]; NIDA NIH HHS [P30 DA011041]
NR 109
TC 7
Z9 7
U1 1
U2 12
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0965-2140
EI 1360-0443
J9 ADDICTION
JI Addiction
PD JAN
PY 2014
VL 109
IS 1
BP 20
EP 32
DI 10.1111/add.12303
PG 13
WC Substance Abuse; Psychiatry
SC Substance Abuse; Psychiatry
GA 268GD
UT WOS:000328157300005
PM 23859638
ER
PT J
AU Charles, LE
Andrew, ME
Sarkisian, K
Li, SQ
Mnatsakanova, A
Violanti, JM
Wilson, M
Gu, JK
Miller, DB
Burchfiel, CM
AF Charles, Luenda E.
Andrew, Michael E.
Sarkisian, Khachatur
Li, Shengqiao
Mnatsakanova, Anna
Violanti, John M.
Wilson, Mark
Gu, Ja K.
Miller, Diane B.
Burchfiel, Cecil M.
TI Associations Between Insulin and Heart Rate Variability in Police
Officers
SO AMERICAN JOURNAL OF HUMAN BIOLOGY
LA English
DT Article
ID SYMPATHETIC-NERVE ACTIVITY; ARCUATE NUCLEUS; AUTONOMIC REGULATION;
BLOOD-PRESSURE; DISEASE; HYPERINSULINEMIA; GLUCOSE; SYSTEM; PREDICTORS;
ACTIVATION
AB ObjectiveLow heart rate variability (HRV) has been linked to cardiovascular disease. Our objective was to examine the cross-sectional association between insulin and HRV.
MethodsInsulin levels were measured in 355 nondiabetic officers from the BCOPS study, following a 12 h fast. HRV was performed according to methods published by the task force of the European Society of Cardiology and the North American Society of Pacing Electrophysiology for measurement and analysis of HRV. Mean values of high (HF) and low frequency (LF) HRV were compared across tertiles of insulin using ANOVA and ANCOVA; p-values were obtained from linear regression models.
ResultsHigher mean levels of insulin were significantly associated with lower (i.e., worse) mean levels of HRV before and after risk-factor adjustment. The results for HF HRV (ms(2)) were as follows: 1st insulin (mu U/ml) tertile (156.3; 95% confidence interval (CI)=128.6-189.9); 2nd tertile (154.3; 95% CI=124.3-191.5); 3rd tertile (127.9; 95% CI=105.0-155.8), p for trend=0.017. Results with LF HRV were similar to HF HRV. Insulin was also inversely and significantly associated with HRV among officers with BMI 25 kg/m(2), with 25.5% body fat, and among those who reported low (= 1 seasonal influenza vaccination in Year 1 (20092010) and Year 2 (2010-2011) were collected on all student grades K through 5 at intervention and control schools from the IIS in the Spring of 2010 and 2011, respectively. Additionally, coverage achieved through SLV-I was compared to coverage of children vaccinated elsewhere. Preliminary data analysis for Year 1 occurred in Spring 2010; final quantitative analysis for both years was completed in late Fall 2012.
Results: Results are shown for 2009-2010 and 2010-2011, respectively: Children enrolled in suburban SLV-I versus control schools had vaccination coverage of 47% vs 36%, and 52% vs 36% (p<0.0001 both years). In urban areas, coverage was 36% vs 26%, and 31% vs 25% (p<0.001 both years). On multilevel logistic analysis with three nested levels (student, school, school district) during both vaccination seasons, children were more likely to be vaccinated in SLV-I versus control schools; ORs were 1.6 (95% CI=1.4, 1.9; p < 0.001) and 1.5 (95% CI=1.3, 1.8; p<0.001).
Conclusions: Delivering influenza vaccine during school is a promising approach to improving pediatric influenza vaccination coverage. (C) 2014 Published by Elsevier Inc. on behalf of American Journal of Preventive Medicine
C1 [Humiston, Sharon G.] Childrens Mercy Hosp & Clin, Dept Pediat, Kansas City, MO 64108 USA.
[Schaffer, Stanley J.; Szilagyi, Peter G.; Blumkin, Aaron K.] Univ Rochester, Med Ctr, Dept Pediat, Rochester, NY 14642 USA.
[Long, Christine E.; Chappel, Tahleah R.] Univ Rochester, Med Ctr, Ctr Community Hlth, Rochester, NY 14642 USA.
[Szydlowski, Jill] Univ Rochester, Med Ctr, Div Hlth Policy & Outcomes Res, Rochester, NY 14642 USA.
[Kolasa, Maureen S.] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Hlth Serv Res & Evaluat Branch, Atlanta, GA USA.
RP Humiston, SG (reprint author), Childrens Mercy Hosp & Clin, Div Emergency & Urgent Care, 2401 Gillham Rd, Kansas City, MO 64108 USA.
EM sghumiston@cmh.edu
OI Schaffer, Stanley/0000-0001-7993-1374
FU CDC National Center for Immunization and Respiratory Diseases (CDC
NCIRD) [055215-002]; School-Based Influenza Immunization Program
FX This study was supported by the CDC National Center for Immunization and
Respiratory Diseases (CDC NCIRD) Grant 055215-002, "School-Based
Influenza Immunization Program." This support did not include the
purchase of any vaccine. The CDC NCIRD Project Officer, Mrs. Kolasa, met
with the team regularly and contributed to the study design,
implementation, analysis, and manuscript preparation. The authors wish
to thank Dr. Andrew Doniger, William Russell, Kim DiMattia, and the many
school personnel who helped implement the school located vaccination
program.
NR 49
TC 7
Z9 7
U1 3
U2 10
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0749-3797
EI 1873-2607
J9 AM J PREV MED
JI Am. J. Prev. Med.
PD JAN
PY 2014
VL 46
IS 1
BP 1
EP 9
DI 10.1016/j.amepre.2013.08.021
PG 9
WC Public, Environmental & Occupational Health; Medicine, General &
Internal
SC Public, Environmental & Occupational Health; General & Internal Medicine
GA 277DO
UT WOS:000328799300001
PM 24355665
ER
PT J
AU Rao, JK
Anderson, LA
Lin, FC
Laux, JP
AF Rao, Jaya K.
Anderson, Lynda A.
Lin, Feng-Chang
Laux, Jeffrey P.
TI Completion of Advance Directives Among US Consumers
SO AMERICAN JOURNAL OF PREVENTIVE MEDICINE
LA English
DT Article
ID COMMUNITY-DWELLING ELDERS; OF-LIFE ISSUES; END; CARE; COMMUNICATION;
PREFERENCES
AB Background: Current, ongoing national surveys do not include questions about end-of-life (EOL) issues. In particular, population-based data are lacking regarding the factors associated with advance directive completion.
Purpose: To characterize U.S. adults who did and did not have an advance directive and examine factors associated with their completion, such as the presence of a chronic condition and regular source of health care.
Methods: Data were analyzed in 2013 from adults aged 18 years and older who participated in the 2009 or 2010 Health Styles Survey, a mail panel survey designed to be representative of the U.S. population. Likelihood ratio tests were used to examine the associations between advance directive completion and demographic and socioeconomic variables (education, income, employment status); presence of a chronic condition; regular source of health care; and self-reported EOL concerns or discussions. Multiple logistic regression analyses identified independent predictors related to advance directive completion.
Results: Of the 7946 respondents, 26.3% had an advance directive. The most frequently reported reason for not having one was lack of awareness. Advance directive completion was associated with older age, more education, and higher income and was less frequent among non-white respondents. Respondents with advance directives also were more likely to report having a chronic disease and a regular source of care. Advance directives were less frequent among those who reported not knowing if they had an EOL concern.
Conclusions: These data indicate racial and educational disparities in advance directive completion and highlight the need for education about their role in facilitating EOL decisions.
C1 [Rao, Jaya K.] Univ N Carolina, Gillings Sch Global Publ Hlth, Div Pharmaceut Outcomes & Policy, Chapel Hill, NC USA.
[Lin, Feng-Chang; Laux, Jeffrey P.] Univ N Carolina, Gillings Sch Global Publ Hlth, Eshelman Sch Pharm, Dept Biostat, Chapel Hill, NC USA.
[Anderson, Lynda A.] CDC, Div Populat Hlth, Appl Res & Translat Branch, Hlth Aging Program, Atlanta, GA 30333 USA.
[Anderson, Lynda A.] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA.
RP Anderson, LA (reprint author), CDC, Div Populat Hlth, MS F78, 4770 Buford Highway NE, Atlanta, GA 30341 USA.
EM laa0@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 31
TC 41
Z9 41
U1 3
U2 16
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0749-3797
EI 1873-2607
J9 AM J PREV MED
JI Am. J. Prev. Med.
PD JAN
PY 2014
VL 46
IS 1
BP 65
EP 70
DI 10.1016/j.amepre.2013.09.008
PG 6
WC Public, Environmental & Occupational Health; Medicine, General &
Internal
SC Public, Environmental & Occupational Health; General & Internal Medicine
GA 277DO
UT WOS:000328799300009
PM 24355673
ER
PT J
AU Ekwueme, DU
Guy, GP
Rim, SH
White, A
Hall, IJ
Fairley, TL
Dean, HD
AF Ekwueme, Donatus U.
Guy, Gery P., Jr.
Rim, Sun Hee
White, Arica
Hall, Ingrid J.
Fairley, Temeika L.
Dean, Hazel D.
TI Health and Economic Impact of Breast Cancer Mortality in Young Women,
1970-2008
SO AMERICAN JOURNAL OF PREVENTIVE MEDICINE
LA English
DT Article
ID SERVICES TASK-FORCE; UNITED-STATES; SCREENING MAMMOGRAPHY; PRODUCTIVITY
COSTS; WHITE WOMEN; BLACK-WOMEN; AGE; PROGNOSIS; SURVIVAL; DIAGNOSIS
AB Background: Breast cancer is the second-leading cause of cancer-related deaths among women aged <50 years. Studies on the effects of breast cancer mortality among young women are limited.
Purpose: To assess trends in breast cancer mortality rates among women aged 20-49 years, estimate years of potential life lost (YPLL), and the value of productivity losses due to premature mortality.
Methods: Age-adjusted rates and rate ratios (RRs) were calculated using 1970-2008 U.S. mortality data. Breast cancer mortality rates over time were assessed using Joinpoint regression modeling. YPLL was calculated using number of cancer deaths and the remaining life expectancy at the age of death. Value of productivity losses was estimated using the number of deaths and the present value of future lifetime earnings.
Results: From 1970 to 2008, the age-adjusted breast cancer mortality rate among young women was 12.02/100,000. Rates were higher in the Northeast (RR=1.03, 95% CI, 1.02-1.04). The annual decline in breast cancer mortality rates among blacks was smaller (-0.68%) compared with whites (-2.02%). The total number of deaths associated with breast cancer was 225,866, which accounted for an estimated 7.98 million YPLL. The estimated total productivity loss in 2008 was $5.49 billion and individual lifetime lost earnings were $1.10 million.
Conclusions: Considering the effect of breast cancer on women of working age and the disproportionate impact on black women, more age-appropriate interventions with multiple strategies are needed to help reduce these substantial health and economic burdens, improve survival, and in turn reduce productivity costs associated with premature death.
C1 [Ekwueme, Donatus U.; Guy, Gery P., Jr.; Rim, Sun Hee; White, Arica; Hall, Ingrid J.; Fairley, Temeika L.] Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Div Canc Prevent & Control, Atlanta, GA 30341 USA.
[Dean, Hazel D.] Ctr Dis Control & Prevent, Natl Ctr HIV,AIDS,Viral Hepatitis,STD & TB Preven, Off Director, Atlanta, GA 30341 USA.
RP Ekwueme, DU (reprint author), Ctr Dis Control & Prevent, Div Canc Prevent & Control, 4770 Buford Highway,Chamblee Bldg 107,MS F-76,Flo, Atlanta, GA 30341 USA.
EM dce3@cdc.gov
NR 53
TC 12
Z9 12
U1 0
U2 5
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0749-3797
EI 1873-2607
J9 AM J PREV MED
JI Am. J. Prev. Med.
PD JAN
PY 2014
VL 46
IS 1
BP 71
EP 79
DI 10.1016/j.amepre.2013.08.016
PG 9
WC Public, Environmental & Occupational Health; Medicine, General &
Internal
SC Public, Environmental & Occupational Health; General & Internal Medicine
GA 277DO
UT WOS:000328799300010
PM 24355674
ER
PT J
AU Roy, SL
Metzger, R
Chen, JG
Laham, FR
Martin, M
Kipper, SW
Smith, LE
Lyon, GM
Haffner, J
Ross, JE
Rye, AK
Johnson, W
Bodager, D
Friedman, M
Walsh, DJ
Collins, C
Inman, B
Davis, BJ
Robinson, T
Paddock, C
Zaki, SR
Kuehnert, M
DaSilva, A
Qvarnstrom, Y
Sriram, R
Visvesvara, GS
AF Roy, S. L.
Metzger, R.
Chen, J. G.
Laham, F. R.
Martin, M.
Kipper, S. W.
Smith, L. E.
Lyon, G. M., III
Haffner, J.
Ross, J. E.
Rye, A. K.
Johnson, W.
Bodager, D.
Friedman, M.
Walsh, D. J.
Collins, C.
Inman, B.
Davis, B. J.
Robinson, T.
Paddock, C.
Zaki, S. R.
Kuehnert, M.
DaSilva, A.
Qvarnstrom, Y.
Sriram, R.
Visvesvara, G. S.
TI Risk for Transmission of Naegleria fowleri From Solid Organ
Transplantation
SO AMERICAN JOURNAL OF TRANSPLANTATION
LA English
DT Article
DE Ameba; amoeba; disseminated; Naegleria; primary amebic
meningoencephalitis; transplant
ID PRIMARY AMEBIC MENINGOENCEPHALITIS; BALAMUTHIA-MANDRILLARIS;
ACANTHAMOEBA SPP.; DONOR; VIRUS; MICE
AB Primary amebic meningoencephalitis (PAM) caused by the free-living ameba (FLA) Naegleria fowleri is a rare but rapidly fatal disease of the central nervous system (CNS) affecting predominantly young, previously healthy persons. No effective chemotherapeutic prophylaxis or treatment has been identified. Recently, three transplant-associated clusters of encephalitis caused by another FLA, Balamuthia mandrillaris, have occurred, prompting questions regarding the suitability of extra-CNS solid organ transplantation from donors with PAM. During 1995-2012, 21 transplant recipients of solid organs donated by five patients with fatal cases of PAM were reported in the United States. None of the recipients developed PAM, and several recipients tested negative for N. fowleri by serology. However, historical PAM case reports and animal experiments with N. fowleri, combined with new postmortem findings from four patients with PAM, suggest that extra-CNS dissemination of N. fowleri can occur and might pose a risk for disease transmission via transplantation. The risks of transplantation with an organ possibly harboring N. fowleri should be carefully weighed for each individual recipient against the potentially greater risk of delaying transplantation while waiting for another suitable organ. In this article, we present a case series and review existing data to inform such risk assessments.
Although Naegleria fowleri solid organ transplant transmission has not been reported to date, human postmortem findings and animal studies suggest that N. fowleri extra-CNS dissemination can occur; therefore the risks of transplantation with an organ from a patient with primary amebic meningoencephalitis should be carefully weighed against the potentially greater risk of delaying transplantation while waiting for another suitable organ.
C1 [Roy, S. L.; Paddock, C.; Zaki, S. R.; Kuehnert, M.; DaSilva, A.; Qvarnstrom, Y.; Sriram, R.; Visvesvara, G. S.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Metzger, R.; Johnson, W.] TransLife Organ Procurement Org, Winter Pk, FL USA.
[Metzger, R.] Florida Hosp Med Ctr, Dept Transplantat, Orlando, FL 32803 USA.
[Chen, J. G.; Laham, F. R.; Martin, M.] Arnold Palmer Hosp Children, Orlando, FL USA.
[Kipper, S. W.] Sedgwick Cty Reg Forens Sci Ctr, Wichita, KS USA.
[Smith, L. E.] Wesley Med Ctr, Wichita, KS USA.
[Lyon, G. M., III] Emory Univ, Sch Med, Atlanta, GA USA.
[Haffner, J.] Tampa Gen Hosp, Tampa, FL 33606 USA.
[Ross, J. E.] Newberry Pathol Associates, Newberry, SC USA.
[Rye, A. K.] Univ S Carolina, Sch Med, Columbia, SC USA.
[Bodager, D.; Friedman, M.] Florida Dept Hlth, Tallahassee, FL USA.
[Walsh, D. J.] Orange Cty Hlth Dept, Orlando, FL USA.
[Collins, C.] Polk Cty Hlth Dept, Bartow, FL USA.
[Inman, B.] Brevard Cty Hlth Dept, Viera, FL USA.
[Davis, B. J.] Essentia Hlth, Duluth, MN USA.
[Robinson, T.] Minnesota Dept Hlth, St Paul, MN USA.
RP Roy, SL (reprint author), Ctr Dis Control & Prevent, Atlanta, GA USA.
EM str2@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 28
TC 2
Z9 2
U1 0
U2 11
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1600-6135
EI 1600-6143
J9 AM J TRANSPLANT
JI Am. J. Transplant.
PD JAN
PY 2014
VL 14
IS 1
BP 163
EP 171
DI 10.1111/ajt.12536
PG 9
WC Surgery; Transplantation
SC Surgery; Transplantation
GA 274HR
UT WOS:000328597900021
PM 24279908
ER
PT J
AU Barbour, KE
Hootman, JM
Helmick, CG
Murphy, LB
Theis, KA
Schwartz, TA
Kalsbeek, WD
Renner, JB
Jordan, JM
AF Barbour, K. E.
Hootman, J. M.
Helmick, C. G.
Murphy, L. B.
Theis, Kristina A.
Schwartz, T. A.
Kalsbeek, W. D.
Renner, J. B.
Jordan, J. M.
TI Meeting Physical Activity Guidelines and the Risk of Incident Knee
Osteoarthritis: A Population-Based Prospective Cohort Study
SO ARTHRITIS CARE & RESEARCH
LA English
DT Article
ID UNITED-STATES; CENSORED-DATA; EXERCISE; QUESTIONNAIRE; PREVALENCE;
ARTHRITIS; IMPACT
AB ObjectiveKnee osteoarthritis (OA) is a leading cause of disability and joint pain. Although other risk factors of knee OA have been identified, how physical activity affects incident knee OA remains unclear.
MethodsUsing data from the first (1999-2004) and second (2005-2010) followup periods of the Johnston County Osteoarthritis Project study, we tested the association between meeting physical activity guidelines and incident knee outcomes among 1,522 adults ages 45 years. The median followup time was 6.5 years (range 4.0-10.2 years). Physical activity at baseline (moderate-equivalent physical activity minutes/week) was calculated using the Minnesota Leisure Time Physical Activity questionnaire. Incident knee radiographic OA (ROA) was defined as the development of Kellgren/Lawrence grade 2 in a knee at followup. Incident knee symptomatic ROA (sROA) was defined as the development of ROA and symptoms in at least 1 knee at followup. Weibull regression modeling was used to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs) for interval-censored data.
ResultsIn multivariable models, meeting the 2008 Department of Health and Human Services (HHS) physical activity guidelines (150 minutes/week) was not significantly associated with ROA (HR 1.20 [95% CI 0.92-1.56]) or sROA (HR 1.24 [95% CI 0.87-1.76]). Adults in the highest level (300 minutes/week) of physical activity had a higher risk of knee ROA and sROA compared with inactive (0 to <10 minutes/week) participants; however, these associations were not statistically significant (HR 1.62 [95% CI 0.97-2.68] and HR 1.42 [95% CI 0.76-2.65], respectively).
ConclusionMeeting the HHS physical activity guidelines was not associated with incident knee ROA or sROA in a cohort of middle-aged and older adults.
C1 [Barbour, K. E.; Hootman, J. M.; Helmick, C. G.; Murphy, L. B.; Theis, Kristina A.] Ctr Dis Control & Prevent, Atlanta, GA 30345 USA.
[Schwartz, T. A.; Kalsbeek, W. D.; Renner, J. B.; Jordan, J. M.] Univ N Carolina, Chapel Hill, NC USA.
RP Barbour, KE (reprint author), Ctr Dis Control & Prevent, 4770 Buford Highway NE,Mailstop K-51, Atlanta, GA 30345 USA.
EM iyk1@cdc.gov
OI Schwartz, Todd/0000-0002-0232-2543
FU Centers for Disease Control and Prevention/Association of Schools of
Public Health [S043, S1734, S3486]; National Institute of Arthritis and
Musculoskeletal and Skin Diseases Multipurpose Arthritis and
Musculoskeletal Disease Center [5-P60-AR30701]; National Institute of
Arthritis and Musculoskeletal and Skin Diseases Multidisciplinary
Clinical Research Center [5-P60-AR49465-03]
FX The Johnston County Osteoarthritis Project was supported in part by the
Centers for Disease Control and Prevention/Association of Schools of
Public Health (cooperative agreements S043, S1734, and S3486), the
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Multipurpose Arthritis and Musculoskeletal Disease Center (grant
5-P60-AR30701), and the National Institute of Arthritis and
Musculoskeletal and Skin Diseases Multidisciplinary Clinical Research
Center (grant 5-P60-AR49465-03).
NR 30
TC 14
Z9 14
U1 1
U2 12
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 2151-464X
EI 2151-4658
J9 ARTHRIT CARE RES
JI Arthritis Care Res.
PD JAN
PY 2014
VL 66
IS 1
BP 139
EP 146
DI 10.1002/acr.22120
PG 8
WC Rheumatology
SC Rheumatology
GA 277DF
UT WOS:000328798400021
PM 23983187
ER
PT J
AU Callaghan, WM
Prefumo, F
AF Callaghan, W. M.
Prefumo, F.
TI Commentary on 'Pregnancy week at delivery and the risk of shoulder
dystocia: a population study of 2 014 956 deliveries'
SO BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
LA English
DT Editorial Material
C1 [Callaghan, W. M.] Ctr Dis Control & Prevent, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30329 USA.
[Prefumo, F.] Univ Brescia, Dept Obstet & Gynaecol, Maternal Fetal Med Unit, Brescia, Italy.
RP Callaghan, WM (reprint author), Ctr Dis Control & Prevent, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30329 USA.
FU Intramural CDC HHS [CC999999]
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1470-0328
EI 1471-0528
J9 BJOG-INT J OBSTET GY
JI BJOG
PD JAN
PY 2014
VL 121
IS 1
BP 42
EP 42
PG 1
WC Obstetrics & Gynecology
SC Obstetrics & Gynecology
GA 275AQ
UT WOS:000328647800005
PM 26436155
ER
PT J
AU Christensen, D
Braun, KVN
Doernberg, NS
Maenner, MJ
Arneson, CL
Durkin, MS
Benedict, RE
Kirby, RS
Wingate, MS
Fitzgerald, R
Yeargin-Allsopp, M
AF Christensen, Deborah
Braun, Kim Van Naarden
Doernberg, Nancy S.
Maenner, Matthew J.
Arneson, Carrie L.
Durkin, Maureen S.
Benedict, Ruth E.
Kirby, Russell S.
Wingate, Martha S.
Fitzgerald, Robert
Yeargin-Allsopp, Marshalyn
TI Prevalence of cerebral palsy, co-occurring autism spectrum disorders,
and motor functioning - Autism and Developmental Disabilities Monitoring
Network, USA, 2008
SO DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
LA English
DT Article
ID UNITED-STATES; CHILDREN; CLASSIFICATION; EUROPE
AB AimThe aim of this study was to report the prevalence and characteristics of children with cerebral palsy (CP).
MethodChildren with CP (n=451) were ascertained by the Autism and Developmental Disabilities Monitoring (ADDM) Network, a population-based, record-review surveillance system monitoring CP in four areas of the USA. Prevalence was calculated as the number of children with CP among all 8-year-old children residing in these areas in 2008. Motor function was categorized by Gross Motor Function Classification System level and walking ability. Co-occurring autism spectrum disorders (ASD) and epilepsy were ascertained using ADDM Network surveillance methodology.
ResultsThe period prevalence of CP for 2008 was 3.1 per 1000 8-year-old children (95% confidence interval 2.8-3.4). Approximately 58% of children walked independently. Co-occurring ASD frequency was 6.9% and was higher (18.4%) among children with non-spastic CP, particularly hypotonic CP. Co-occurring epilepsy frequency was 41% overall, did not differ by ASD status or CP subtype, and was highest (67%) among children with limited or no walking ability.
InterpretationThe prevalence of CP in childhood from US surveillance data has remained relatively constant, in the range of 3.1 to 3.6 per 1000, since 1996. The higher frequency of ASD in non-spastic than in spastic subtypes of CP calls for closer examination.
This article is commented on by Zwaigenbaum on pages of this issue.
C1 [Christensen, Deborah; Braun, Kim Van Naarden; Doernberg, Nancy S.; Yeargin-Allsopp, Marshalyn] Ctr Dis Control & Prevent, Div Birth Defects & Dev Disabil, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USA.
[Maenner, Matthew J.; Arneson, Carrie L.; Durkin, Maureen S.; Benedict, Ruth E.] Univ Wisconsin, Waisman Ctr, Madison, WI 53705 USA.
[Maenner, Matthew J.; Durkin, Maureen S.] Univ Wisconsin, Dept Populat Hlth Sci, Madison, WI USA.
[Benedict, Ruth E.] Univ Wisconsin, Dept Kinesiol, Occupat Therapy Program, Madison, WI USA.
[Kirby, Russell S.] Univ S Florida, Coll Publ Hlth, Dept Community & Family Hlth, Tampa, FL USA.
[Wingate, Martha S.] Univ Alabama Birmingham, Sch Publ Hlth, Dept Hlth Care Org & Policy, Birmingham, AL 35294 USA.
[Fitzgerald, Robert] Washington Univ, Dept Psychiat, St Louis, MO USA.
RP Christensen, D (reprint author), Ctr Dis Control & Prevent, Div Birth Defects & Dev Disabil, Natl Ctr Birth Defects & Dev Disabil, 1600 Clifton Rd NE,MS E-86, Atlanta, GA 30333 USA.
EM dqc3@cdc.gov
RI Durkin, Maureen/B-7834-2015
FU NICHD NIH HHS [P30 HD003352]
NR 23
TC 42
Z9 44
U1 3
U2 16
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0012-1622
EI 1469-8749
J9 DEV MED CHILD NEUROL
JI Dev. Med. Child Neurol.
PD JAN
PY 2014
VL 56
IS 1
BP 59
EP 65
DI 10.1111/dmcn.12268
PG 7
WC Clinical Neurology; Pediatrics
SC Neurosciences & Neurology; Pediatrics
GA 267WG
UT WOS:000328128400013
PM 24117446
ER
PT J
AU Rogowski, WH
Grosse, SD
Schmidtke, J
Marckmann, G
AF Rogowski, Wolf H.
Grosse, Scott D.
Schmidtke, Joerg
Marckmann, Georg
TI Criteria for fairly allocating scarce health-care resources to genetic
tests: which matter most?
SO EUROPEAN JOURNAL OF HUMAN GENETICS
LA English
DT Article
DE health-care prioritization; genetic testing; costs and cost analysis;
resource allocation; ethics
ID COST-EFFECTIVENESS ANALYSIS; TECHNOLOGY-ASSESSMENT; PRENATAL-DIAGNOSIS;
SERVICES; EQUITY; PERSPECTIVES; PRINCIPLES; DISORDERS; GERMANY; EUROPE
AB The use of genetic tests is expanding rapidly. Given limited health-care budgets throughout Europe and few national coverage decisions specifically for genetic tests, decisions about allocating scarce resources to genetic tests are frequently ad hoc and left to lower-level decision makers. This study assesses substantive ethical and economic criteria to prioritize genetic services in a reasonable and fair manner. Principles for allocating health-care resources can be classified into four categories: need-based allocation; maximizing total benefits; treating people equally; and promoting and rewarding social usefulness. In the face of scarcity, the degree of an individual's need for medical intervention is an important criterion. Also, different economic concepts of efficiency are of relevance in the theory and practice of prioritizing genetic tests. Equity concerns are most likely to be relevant in terms of avoiding undesirable inequities, which may also set boundaries to the use of efficiency as a prioritization criterion. The aim of promoting and rewarding social usefulness is unlikely to be relevant to the question of what priority a genetic test should have in clinical practice. Further work is needed to select an appropriate set of criteria; operationalize them; and assign weights before some kind of standardized priority information can be added to information sources for genetic services. Besides the substantive criteria, formal considerations like those pointed out in the framework of accountability for reasonableness need to be considered in decision making.
C1 [Rogowski, Wolf H.] German Res Ctr Environm Hlth GmbH, Helmholtz Zentrum Munchen, D-85764 Neuherberg, Germany.
[Rogowski, Wolf H.] Univ Munich, Inst & Outpatient Clin Occupat Social & Environm, Ctr Clin, Munich, Germany.
[Grosse, Scott D.] Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA USA.
[Schmidtke, Joerg] Hannover Med Sch, Inst Human Genet, Hannover, Germany.
[Marckmann, Georg] Univ Munich, Inst Eth Hist & Theory Med, Munich, Germany.
RP Rogowski, WH (reprint author), German Res Ctr Environm Hlth GmbH, Helmholtz Zentrum Munchen, Ingolstadter Landstr 1, D-85764 Neuherberg, Germany.
EM rogowski@helmholtz-muenchen.de
FU EuroGentest, an EU [512148]; EuroGentest2 [261469]
FX We acknowledge the comments from various colleagues, especially Per
Carlsson, Jurgen John, Helena Kaariainen, Alastair Kent, Michael
Krawczak, Ulf Kristofferson and Irma Nippert. All errors of omission and
commission remain our own. The study was partly supported by
EuroGentest, an EU FP6 supported NoE Contract Number 512148 (EuroGentest
Unit 3: Clinical genetics, community genetics and public health,
Workpackage 3.2 (J Schmidtke)) and its successor EuroGentest2 (contract
number 261469).
NR 56
TC 9
Z9 9
U1 4
U2 16
PU NATURE PUBLISHING GROUP
PI LONDON
PA MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1018-4813
EI 1476-5438
J9 EUR J HUM GENET
JI Eur. J. Hum. Genet.
PD JAN
PY 2014
VL 22
IS 1
BP 25
EP 31
DI 10.1038/ejhg.2013.172
PG 7
WC Biochemistry & Molecular Biology; Genetics & Heredity
SC Biochemistry & Molecular Biology; Genetics & Heredity
GA 275PP
UT WOS:000328689600011
PM 23921536
ER
PT J
AU Zolotusca, L
Jorgensen, P
Popovici, O
Pistol, A
Popovici, F
Widdowson, MA
Alexandrescu, V
Ivanciuc, A
Cheng, PY
Gross, D
Brown, CS
Mott, JA
AF Zolotusca, Laurentiu
Jorgensen, Pernille
Popovici, Odette
Pistol, Adriana
Popovici, Florin
Widdowson, Marc-Alain
Alexandrescu, Viorel
Ivanciuc, Alina
Cheng, Po-Yung
Gross, Diane
Brown, Caroline S.
Mott, Joshua A.
TI Risk factors associated with fatal influenza, Romania, October 2009-May
2011
SO INFLUENZA AND OTHER RESPIRATORY VIRUSES
LA English
DT Article
DE Influenza; risk factors; Romania; severe acute respiratory illness;
surveillance
ID H1N1 INFLUENZA; UNITED-STATES; WOMEN
AB Background Limited data are available from Central and Eastern Europe on risk factors for severe complications of influenza. Such data are essential to prioritize prevention and treatment resources and to adapt influenza vaccination recommendations.
Objectives To use sentinel surveillance data to identify risk factors for fatal outcomes among hospitalized patients with severe acute respiratory infections (SARI) and among hospitalized patients with laboratory-confirmed influenza.
Methods Retrospective analysis of case-based surveillance data collected from sentinel hospitals in Romania during the 2009/2010 and 2010/2011 winter influenza seasons was performed to evaluate risk factors for fatal outcomes using multivariate logistic regression.
Results During 2009/2010 and 2010/2011, sentinel hospitals reported 661 SARI patients of which 230 (35%) tested positive for influenza. In the multivariate analyses, infection with influenza A(H1N1)pdm09 was the strongest risk factor for death among hospitalized SARI patients (OR: 66; 95% CI: 33-131). Among patients positive for influenza A(H1N1)pdm09 virus infection (n=148), being pregnant (OR: 71; 95% CI: 16-312), clinically obese (OR: 29;95% CI: 16-312), and having an immunocompromising condition (OR: 37;95% CI: 11-134) were significantly associated with fatal outcomes.
Conclusion These findings are consistent with several other investigations of risk factors associated with influenza A(H1N1)pdm09 virus infections. They also support the more recent 2012 recommendations by the WHO Strategic Advisory Group of Experts on Immunization (SAGE) that pregnant women are an important risk group for influenza vaccination. Ongoing sentinel surveillance can be useful tool to monitor risk factors for complications of influenza virus infections during each influenza season, and pandemics as well.
C1 [Zolotusca, Laurentiu] Minist Hlth, Bucharest, Romania.
[Jorgensen, Pernille; Brown, Caroline S.] WHO Reg Off Europe, Copenhagen, Denmark.
[Popovici, Odette; Pistol, Adriana; Popovici, Florin] Natl Inst Publ Hlth, Bucharest, Romania.
[Widdowson, Marc-Alain; Cheng, Po-Yung; Gross, Diane; Mott, Joshua A.] US Ctr Dis Control & Prevent, Influenza Div, Atlanta, GA USA.
[Alexandrescu, Viorel; Ivanciuc, Alina] Cantacuzino Inst Res & Dev Microbiol & Immunol, Bucharest, Romania.
RP Mott, JA (reprint author), KEMRI Headquarters, Ctr Dis Control & Prevent Kenya, Influenza Program, Mbagathi Rd,Off Mbagathi Way,POB 606, Nairobi 00621, Kenya.
EM jmott@ke.cdc.gov
NR 14
TC 1
Z9 2
U1 2
U2 14
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1750-2640
EI 1750-2659
J9 INFLUENZA OTHER RESP
JI Influenza Other Respir. Viruses
PD JAN
PY 2014
VL 8
IS 1
BP 8
EP 12
DI 10.1111/irv.12209
PG 5
WC Infectious Diseases; Virology
SC Infectious Diseases; Virology
GA 275VA
UT WOS:000328704900002
PM 24251915
ER
PT J
AU Levy, JW
Suntarattiwong, P
Simmerman, JM
Jarman, RG
Johnson, K
Olsen, SJ
Chotpitayasunondh, T
AF Levy, Jens W.
Suntarattiwong, Piyarat
Simmerman, James M.
Jarman, Richard G.
Johnson, Kara
Olsen, Sonja J.
Chotpitayasunondh, Tawee
TI Increased hand washing reduces influenza virus surface contamination in
Bangkok households, 2009-2010
SO INFLUENZA AND OTHER RESPIRATORY VIRUSES
LA English
DT Article
DE Human; influenza; Thailand; transmission
ID A VIRUS; TRANSMISSION; SURVIVAL; THAILAND
AB Within a hand-washing clinical trial, we evaluated factors associated with fomite contamination in households with an influenza-infected child. Influenza virus RNA contamination was higher in households with low absolute humidity and in control households, suggesting that hand washing reduces surface contamination.
C1 [Levy, Jens W.; Simmerman, James M.; Olsen, Sonja J.] Thailand MOPH US CDC Collaborat, Int Emerging Infect Program, Nonthaburi 11000, Thailand.
[Suntarattiwong, Piyarat; Chotpitayasunondh, Tawee] Queen Sirikit Natl Inst Child Hlth, Bangkok, Thailand.
[Simmerman, James M.; Olsen, Sonja J.] Ctr Dis Control & Prevent, Influenza Div, Atlanta, GA USA.
[Jarman, Richard G.] US Armed Forces Res Inst Med Sci, Bangkok, Thailand.
[Johnson, Kara] Harvard Univ, Sch Med, Boston, MA USA.
RP Levy, JW (reprint author), Thailand MOPH US CDC Collaborat, Minist Publ Hlth, DDC Bldg 7,Soi 4,Tivanon Rd, Nonthaburi 11000, Thailand.
EM jenslevy@gmail.com; sco2@cdc.gov
FU U.S. CDC [5U51IP000345]; Armed Forces Health Surveillance Center -
Global Emerging Infections Surveillance and Response System
FX This work was supported by funding from the U.S. CDC (cooperative
agreement #5U51IP000345).A portion of the laboratory work was funded by
the Armed Forces Health Surveillance Center - Global Emerging Infections
Surveillance and Response System.
NR 12
TC 2
Z9 2
U1 0
U2 3
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1750-2640
EI 1750-2659
J9 INFLUENZA OTHER RESP
JI Influenza Other Respir. Viruses
PD JAN
PY 2014
VL 8
IS 1
BP 13
EP 16
DI 10.1111/irv.12204
PG 4
WC Infectious Diseases; Virology
SC Infectious Diseases; Virology
GA 275VA
UT WOS:000328704900003
PM 24373290
ER
PT J
AU Yu, HJ
Huang, JG
Huai, Y
Guan, XH
Klena, J
Liu, SL
Peng, YX
Yang, H
Luo, J
Zheng, JD
Chen, MY
Peng, ZB
Xiang, NJ
Huo, XX
Xiao, L
Jiang, H
Chen, H
Zhang, YZ
Xing, XS
Xu, Z
Feng, ZJ
Zhan, FX
Yang, WZ
Uyeki, TM
Wang, Y
Varma, JK
AF Yu, Hongjie
Huang, Jigui
Huai, Yang
Guan, Xuhua
Klena, John
Liu, Shali
Peng, Youxing
Yang, Hui
Luo, Jun
Zheng, Jiandong
Chen, Maoyi
Peng, Zhibin
Xiang, Nijuan
Huo, Xixiang
Xiao, Lin
Jiang, Hui
Chen, Hui
Zhang, Yuzhi
Xing, Xuesen
Xu, Zhen
Feng, Zijian
Zhan, Faxian
Yang, Weizhong
Uyeki, Timothy M.
Wang, Yu
Varma, Jay K.
TI The substantial hospitalization burden of influenza in central China:
surveillance for severe, acute respiratory infection, and influenza
viruses, 2010-2012
SO INFLUENZA AND OTHER RESPIRATORY VIRUSES
LA English
DT Article
DE China; disease burden; influenza; seasonality
ID CHILDREN YOUNGER; B VIRUS; SEASONAL INFLUENZA; UNITED-STATES; HONG-KONG;
DISEASE; POPULATION; PNEUMONIA; MORTALITY; EPIDEMIC
AB Background Published data on influenza in severe acute respiratory infection (SARI) patients are limited. We conducted SARI surveillance in central China and estimated hospitalization rates of SARI attributable to influenza by viral type/subtype.
Methods Surveillance was conducted at four hospitals in Jingzhou, China from 2010 to 2012. We enrolled hospitalized patients who had temperature 373 degrees C and at least one of: cough, sore throat, tachypnea, difficulty breathing, abnormal breath sounds on auscultation, sputum production, hemoptysis, chest pain, or chest radiograph consistent with pneumonia. A nasopharyngeal swab was collected from each case-patient within 24hours of admission for influenza testing by real-time reverse transcription PCR.
Results Of 17172 SARI patients enrolled, 90% were aged <15years. The median duration of hospitalization was 5days. Of 16208 (94%) SARI cases tested, 2057 (13%) had confirmed influenza, including 1427 (69%) aged <5years. Multiple peaks of influenza occurred during summer, winter, and spring months. Influenza was associated with an estimated 115 and 142 SARI hospitalizations per 100000 during 2010-2011 and 2011-2012 [including A(H3N2): 55 and 44 SARI hospitalizations per 100000; pandemic A(H1N1): 33 SARI hospitalizations per 100000 during 2010-2011; influenza B: 26 and 98 hospitalizations per 100000], with the highest rate among children aged 6-11months (3603 and 3805 hospitalizations per 100000 during 2010-2011 and 2011-2012, respectively).
Conclusions In central China, influenza A and B caused a substantial number of hospitalizations during multiple periods each year. Our findings strongly suggest that young children should be the highest priority group for annual influenza vaccination in China.
C1 [Yu, Hongjie; Zheng, Jiandong; Peng, Zhibin; Jiang, Hui; Xu, Zhen] Chinese Ctr Dis Control & Prevent, Div Infect Dis, Beijing 100050, Peoples R China.
[Huang, Jigui; Chen, Maoyi; Xiao, Lin] Jingzhou Ctr Dis Control & Prevent, Jingzhou, Peoples R China.
[Huai, Yang; Klena, John; Zhang, Yuzhi; Varma, Jay K.] US Ctr Dis Control & Prevent, China US Collaborat Program Emerging & Reemerging, Beijing, Peoples R China.
[Guan, Xuhua; Huo, Xixiang; Chen, Hui; Xing, Xuesen; Zhan, Faxian] Hubei Prov Ctr Dis Control & Prevent, Wuhan, Peoples R China.
[Liu, Shali] Jingzhou Cent Hosp, Jingzhou, Peoples R China.
[Peng, Youxing] Jingzhou First Peoples Hosp, Jingzhou, Peoples R China.
[Yang, Hui] Jingzhou Second Peoples Hosp, Jingzhou, Peoples R China.
[Luo, Jun] Jingzhou Maternal & Childrens Hosp, Jingzhou, Peoples R China.
[Xiang, Nijuan; Feng, Zijian] Chinese Ctr Dis Control & Prevent, Publ Hlth Emergency Ctr, Beijing, Peoples R China.
[Yang, Weizhong; Wang, Yu] Chinese Ctr Dis Control & Prevent, Beijing 100050, Peoples R China.
[Uyeki, Timothy M.] Ctr Dis Control & Prevent, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA USA.
[Varma, Jay K.] Ctr Dis Control & Prevent, Global Dis Detect Program, Div Global Dis Detect & Response, Ctr Global Hlth, Atlanta, GA USA.
RP Wang, Y (reprint author), Chinese Ctr Dis Control & Prevent, Beijing 100050, Peoples R China.
EM wangyu@chinacdc.cn; jvarma@cdc.gov
FU China-U.S. Collaborative Program on Emerging and Re-emerging Infectious
Diseases
FX This study was supported by grants from the China-U.S. Collaborative
Program on Emerging and Re-emerging Infectious Diseases. None of the
funders had any role in the study design and the collection, analysis,
and interpretation of data, or in the writing of the article and the
decision to submit it for publication.
NR 42
TC 13
Z9 18
U1 4
U2 15
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1750-2640
EI 1750-2659
J9 INFLUENZA OTHER RESP
JI Influenza Other Respir. Viruses
PD JAN
PY 2014
VL 8
IS 1
BP 53
EP 65
DI 10.1111/irv.12205
PG 13
WC Infectious Diseases; Virology
SC Infectious Diseases; Virology
GA 275VA
UT WOS:000328704900009
PM 24209711
ER
PT J
AU Shapiro, DJ
Hicks, LA
Pavia, AT
Hersh, AL
AF Shapiro, Daniel J.
Hicks, Lauri A.
Pavia, Andrew T.
Hersh, Adam L.
TI Antibiotic prescribing for adults in ambulatory care in the USA, 2007-09
SO JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
LA English
DT Article
DE antibiotic stewardship; antibiotic resistance; prescribing patterns
ID RESPIRATORY-TRACT INFECTIONS; STAPHYLOCOCCUS-AUREUS INFECTIONS;
CLINICAL-PRACTICE GUIDELINES; UNITED-STATES; STREPTOCOCCUS-PNEUMONIAE;
EMERGENCY-DEPARTMENT; RESISTANCE; SETTINGS; PRESCRIPTIONS; POPULATION
AB Objectives: To determine patterns of ambulatory antibiotic prescribing in US adults, including the use of broad-spectrum versus narrow-spectrum agents, to provide a description of the diagnoses for which antibiotics are prescribed and to identify patient and physician factors associated with broad-spectrum antibiotic prescribing.
Methods: We used data for patients aged >= 18 years from the National Ambulatory and National Hospital Ambulatory Medical Care Surveys (2007-09). These are nationally representative surveys of patient visits to offices, hospital outpatient departments and emergency departments (EDs) in the USA, collectively referred to as ambulatory visits. We determined the types of antibiotics prescribed, including the use of broad-spectrum versus narrow-spectrum antibiotics, and examined prescribing patterns by diagnoses. We used multivariable logistic regression to identify factors associated with broad-spectrum antibiotic prescribing.
Results: Antibiotics were prescribed during 101 million (95% CI:91-111 million) ambulatory visits annually, representing 10% of all visits. Broad-spectrum agents were prescribed during 61% of visits in which antibiotics were prescribed. The most commonly prescribed antibiotics were quinolones (25% of antibiotics), macrolides (20%) and aminopenicillins (12%). Antibiotics were most commonly prescribed for respiratory conditions(41% of antibiotics), skin/mucosal conditions (18%) and urinary tract infections (9%). In multivariable analysis, among patients prescribed antibiotics, broad-spectrum agents were more likely to be prescribed than narrow-spectrum antibiotics for respiratory infections for which antibiotics are rarely indicated (e. g. bronchitis), during visits to EDs and for patients >= 60 years.
Conclusions: Broad-spectrum agents constitute the majority of antibiotics in ambulatory care. More than 25% of prescriptions are for conditions for which antibiotics are rarely indicated. Antibiotic stewardship interventions targeting respiratory and non-respiratory conditions are needed in ambulatory care.
C1 [Shapiro, Daniel J.] Univ Calif San Francisco, Sch Med, San Francisco, CA USA.
[Hicks, Lauri A.] Ctr Dis Control & Prevent, Resp Dis Branch, Atlanta, GA USA.
[Pavia, Andrew T.; Hersh, Adam L.] Univ Utah, Dept Pediat, Div Pediat Infect Dis, Salt Lake City, UT 84112 USA.
RP Hersh, AL (reprint author), Univ Utah, Dept Pediat, Div Pediat Infect Dis, Salt Lake City, UT 84112 USA.
EM adam.hersh@hsc.utah.edu
FU Centers for Disease Control and Prevention [200-2010-M-36230, IPA
110369]
FX This work was supported by contract number 200-2010-M-36230 and IPA
110369 from the Centers for Disease Control and Prevention.
NR 34
TC 63
Z9 63
U1 1
U2 10
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0305-7453
EI 1460-2091
J9 J ANTIMICROB CHEMOTH
JI J. Antimicrob. Chemother.
PD JAN
PY 2014
VL 69
IS 1
BP 234
EP 240
DI 10.1093/jac/dkt301
PG 7
WC Infectious Diseases; Microbiology; Pharmacology & Pharmacy
SC Infectious Diseases; Microbiology; Pharmacology & Pharmacy
GA 271XR
UT WOS:000328425400034
PM 23887867
ER
PT J
AU Frasch, HF
Dotson, GS
Bunge, AL
Chen, CP
Cherrie, JW
Kasting, GB
Kissel, JC
Sahmel, J
Semple, S
Wilkinson, S
AF Frasch, H. Frederick
Dotson, G. Scott
Bunge, Annette L.
Chen, Chen-Peng
Cherrie, John W.
Kasting, Gerald B.
Kissel, John C.
Sahmel, Jennifer
Semple, Sean
Wilkinson, Simon
TI Analysis of finite dose dermal absorption data: Implications for dermal
exposure assessment
SO JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
LA English
DT Article
DE risk assessment; skin absorption; percent absorption; fractional
absorption; dermal load; maximum flux; evaporation
ID SKIN IN-VITRO; PERCUTANEOUS-ABSORPTION; VOLATILE COMPOUNDS; KINETICS;
SOLVENTS
AB A common dermal exposure assessment strategy estimates the systemic uptake of chemical in contact with skin using the fixed fractional absorption approach: the dermal absorbed dose is estimated as the product of exposure and the fraction of applied chemical that is absorbed, assumed constant for a given chemical. Despite the prominence of this approach there is little guidance regarding the evaluation of experiments from which fractional absorption data are measured. An analysis of these experiments is presented herein, and limitations to the fixed fractional absorption approach are discussed. The analysis provides a set of simple algebraic expressions that may be used in the evaluation of finite dose dermal absorption experiments, affording a more data-driven approach to dermal exposure assessment. Case studies are presented that demonstrate the application of these tools to the assessment of dermal absorption data.
C1 [Frasch, H. Frederick] NIOSH, Hlth Effects Lab, Morgantown, WV 26505 USA.
[Dotson, G. Scott] NIOSH, Educ & Informat Div, Cincinnati, OH USA.
[Bunge, Annette L.] Colorado Sch Mines, Dept Chem & Biol Engn, Golden, CO 80401 USA.
[Chen, Chen-Peng] China Med Univ, Coll Publ Hlth, Dept Occupat Safety & Hlth, Taichung, Taiwan.
[Cherrie, John W.] Inst Occupat Med, Edinburgh EH8 9SV, Midlothian, Scotland.
[Kasting, Gerald B.] Univ Cincinnati, Winkle Coll Pharm, Cincinnati, OH USA.
[Kissel, John C.] Univ Washington, Dept Environm & Occupat Hlth Sci, Seattle, WA 98195 USA.
[Sahmel, Jennifer] ChemRisk, Boulder, CO USA.
[Semple, Sean] Univ Aberdeen, Div Appl Hlth Sci, Aberdeen, Scotland.
[Wilkinson, Simon] Univ Newcastle, Med Toxicol Ctr, Inst Cellular Med, Newcastle Upon Tyne, Tyne & Wear, England.
RP Frasch, HF (reprint author), NIOSH, Hlth Effects Lab, Morgantown, WV 26505 USA.
EM HFrasch@cdc.gov
RI Bunge, Annette/A-7995-2012;
OI Bunge, Annette/0000-0002-0287-3724; Semple, Sean/0000-0002-0462-7295
NR 37
TC 11
Z9 11
U1 4
U2 24
PU NATURE PUBLISHING GROUP
PI NEW YORK
PA 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA
SN 1559-0631
EI 1559-064X
J9 J EXPO SCI ENV EPID
JI J. Expo. Sci. Environ. Epidemiol.
PD JAN-FEB
PY 2014
VL 24
IS 1
BP 65
EP 73
DI 10.1038/jes.2013.23
PG 9
WC Environmental Sciences; Public, Environmental & Occupational Health;
Toxicology
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health; Toxicology
GA 274KJ
UT WOS:000328604900010
PM 23715085
ER
PT J
AU Suchdev, PS
Ruth, LJ
Earley, M
Macharia, A
Williams, TN
AF Suchdev, Parminder S.
Ruth, Laird J.
Earley, Marie
Macharia, Alex
Williams, Thomas N.
TI The burden and consequences of inherited blood disorders among young
children in western Kenya
SO MATERNAL AND CHILD NUTRITION
LA English
DT Article
DE sickle cell disorders; haemoglobinopathies; thalassaemia; G6PD
deficiency; haptoglobins; anaemia
ID PLASMODIUM-FALCIPARUM MALARIA; VITAMIN-A-DEFICIENCY;
SICKLE-CELL-DISEASE; ALPHA(+)-THALASSEMIA PROTECTS; PRESCHOOL-CHILDREN;
IRON-DEFICIENCY; HEMOGLOBIN; ANEMIA; HAPTOGLOBIN; TRAIT
AB Although inherited blood disorders are common among children in many parts of Africa, limited data are available about their prevalence or contribution to childhood anaemia. We conducted a cross-sectional survey of 858 children aged 6-35 months who were randomly selected from 60 villages in western Kenya. Haemoglobin (Hb), ferritin, malaria, C-reactive protein (CRP) and retinol binding protein (RBP) were measured from capillary blood. Using polymerase chain reaction (PCR), Hb type, -3.7kb alpha-globin chain deletion, glucose-6-phosphate dehydrogenase (G6PD) genotype and haptoglobin (Hp) genotype were determined. More than 2 out of 3 children had at least one measured blood disorder. Sickle cell trait (HbAS) and disease (HbSS) were found in 17.1% and 1.6% of children, respectively; 38.5% were heterozygotes and 9.6% were homozygotes for (+)-thalassaemia. The Hp 2-2 genotype was found in 20.4% of children, whereas 8.2% of males and 6.8% of children overall had G6PD deficiency. There were no significant differences in the distribution of malaria by the measured blood disorders, except among males with G6PD deficiency who had a lower prevalence of clinical malaria than males of normal G6PD genotype (P=0.005). After excluding children with malaria parasitaemia, inflammation (CRP>5mgL(-1)), iron deficiency (ferritin<12gL(-1)) or vitamin A deficiency (RBP<0.7gL(-1)), the prevalence of anaemia among those without (+)-thalassaemia (43.0%) remained significantly lower than that among children who were either heterozygotes (53.5%) or homozygotes (67.7%, P=0.03). Inherited blood disorders are common among pre-school children in western Kenya and are important contributors to anaemia.
C1 [Suchdev, Parminder S.; Ruth, Laird J.] Ctr Dis Control & Prevent, Nutr Branch, Atlanta, GA 30341 USA.
[Suchdev, Parminder S.] Emory Univ, Dept Pediat & Global Hlth, Atlanta, GA 30322 USA.
[Earley, Marie] CDC, Newborn Screening Qual Assurance Program, Atlanta, GA 30333 USA.
[Macharia, Alex; Williams, Thomas N.] KEMRI Ctr Geog Med Res Coast, Kilifi, Kenya.
[Williams, Thomas N.] Nuffield Dept Clin Med, Oxford, England.
[Williams, Thomas N.] INDEPTH Network, Accra, Ghana.
RP Suchdev, PS (reprint author), Ctr Dis Control & Prevent, Nutr Branch, 4770 Buford Highway NE,MS K25, Atlanta, GA 30341 USA.
EM psuchdev@cdc.gov
OI Suchdev, Parmi/0000-0002-0350-3469
FU US Centers for Disease Control and Prevention, Atlanta; Wellcome Trust,
UK [091758]
FX This work was supported by the US Centers for Disease Control and
Prevention, Atlanta, through a cooperative agreement between CDC and the
Kenya Medical Research Institute. TNW is supported by a Senior
Fellowship from the Wellcome Trust, UK (091758).
NR 36
TC 9
Z9 10
U1 2
U2 12
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1740-8695
EI 1740-8709
J9 MATERN CHILD NUTR
JI Matern. Child Nutr.
PD JAN
PY 2014
VL 10
IS 1
BP 135
EP 144
DI 10.1111/j.1740-8709.2012.00454.x
PG 10
WC Nutrition & Dietetics; Pediatrics
SC Nutrition & Dietetics; Pediatrics
GA 273ZB
UT WOS:000328573700010
PM 22973867
ER
PT J
AU Fisher, D
Li, CM
Chiu, MS
Themann, CL
Petersen, H
Jonasson, F
Jonsson, PV
Sverrisdottir, JE
Garcia, M
Harris, TB
Launer, LJ
Eiriksdottir, G
Gudnason, V
Hoffman, HJ
Cotch, MF
AF Fisher, Diana
Li, Chuan-Ming
Chiu, May S.
Themann, Christa L.
Petersen, Hannes
Jonasson, Frithbert
Jonsson, Palmi V.
Sverrisdottir, Johanna Eyrun
Garcia, Melissa
Harris, Tamara B.
Launer, Lenore J.
Eiriksdottir, Gudny
Gudnason, Vilmundur
Hoffman, Howard J.
Cotch, Mary Frances
TI Impairments in hearing and vision impact on mortality in older people:
the AGES-Reykjavik Study
SO AGE AND AGEING
LA English
DT Article
DE AGES-Reykjavik study; hearing; vision; dual sensory impairment;
all-cause mortality; cardiovascular disease mortality; older people
ID HEALTH INTERVIEW SURVEY; VISUAL IMPAIRMENT; SENSORY IMPAIRMENT;
FOLLOW-UP; POPULATION; DISABILITY; CATARACT; PROJECT; ACUITY; ADULTS
AB Objective: to examine the relationships between impairments in hearing and vision and mortality from all-causes and cardiovascular disease (CVD) among older people.
Design: population-based cohort study.
Participants: the study population included 4,926 Icelandic individuals, aged >= 67 years, 43.4% male, who completed vision and hearing examinations between 2002 and 2006 in the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-RS) and were followed prospectively for mortality through 2009.
Methods: participants were classified as having 'moderate or greater' degree of impairment for vision only (VI), hearing only (HI), and both vision and hearing (dual sensory impairment, DSI). Cox proportional hazard regression, with age as the time scale, was used to calculate hazard ratios (HR) associated with impairment and mortality due to all-causes and specifically CVD after a median follow-up of 5.3 years.
Results: the prevalence of HI, VI and DSI were 25.4, 9.2 and 7.0%, respectively. After adjusting for age, significantly (P < 0.01) increased mortality from all causes, and CVD was observed for HI and DSI, especially among men. After further adjustment for established mortality risk factors, people with HI remained at higher risk for CVD mortality [HR: 1.70 (1.27-2.27)], whereas people with DSI remained at higher risk of all-cause mortality [HR: 1.43 (1.11-1.85)] and CVD mortality [HR: 1.78 (1.18-2.69)]. Mortality rates were significantly higher in men with HI and DSI and were elevated, although not significantly, among women with HI.
Conclusions: older men with HI or DSI had a greater risk of dying from any cause and particularly cardiovascular causes within a median 5-year follow-up. Women with hearing impairment had a non-significantly elevated risk. Vision impairment alone was not associated with increased mortality.
C1 [Fisher, Diana; Cotch, Mary Frances] NEI, Div Epidemiol & Clin Applicat, NIH, Bethesda, MD 20892 USA.
[Li, Chuan-Ming; Chiu, May S.; Hoffman, Howard J.] NIDCD, Div Sci Programs, Epidemiol & Stat Program, NIH, Bethesda, MD USA.
[Themann, Christa L.] NIOSH, Hearing Loss Prevent Team, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA.
[Petersen, Hannes; Jonasson, Frithbert; Jonsson, Palmi V.; Gudnason, Vilmundur] Univ Iceland, Fac Med, Reykjavik, Iceland.
[Petersen, Hannes] Landspitali Univ Hosp, Dept Otolaryngol Head & Neck Surg, Reykjavik, Iceland.
[Jonasson, Frithbert] Landspitali Univ Hosp, Reykjavik, Iceland.
[Jonsson, Palmi V.] Landspitali Univ Hosp, Dept Geriatr, IS-101 Reykjavjk, Iceland.
[Sverrisdottir, Johanna Eyrun; Eiriksdottir, Gudny; Gudnason, Vilmundur] Iceland Heart Assoc, Kopavogur, Iceland.
[Garcia, Melissa; Harris, Tamara B.; Launer, Lenore J.] NIA, Lab Epidemiol Demog & Biometry, Intramural Res Program, NIH, Bethesda, MD 20892 USA.
RP Fisher, D (reprint author), NEI, Div Epidemiol & Clin Applicat, NIH, Bethesda, MD 20892 USA.
EM diana.fisher@nih.gov
RI Gudnason, Vilmundur/K-6885-2015;
OI Gudnason, Vilmundur/0000-0001-5696-0084; Cotch, Mary
Frances/0000-0002-2046-4350
FU National Institutes of Health, National Institute on Aging (NIA)
[N01-AG-12100]; NIA [Z01-AG007380]; National Eye Institute (NEI)
[ZIAEY000401]; National Institute on Deafness and Other Communication
Disorders (NIDCD) Division of Scientific Programs [IAA Y2-DC-1004-02];
Hjartavernd (Icelandic Heart Association); Althingi (Icelandic
Parliament)
FX This work was supported by the National Institutes of Health, National
Institute on Aging (NIA) (contract number N01-AG-12100); the NIA
Intramural Research Program (Z01-AG007380); the National Eye Institute
(NEI) Intramural Research Program (ZIAEY000401); the National Institute
on Deafness and Other Communication Disorders (NIDCD) Division of
Scientific Programs (IAA Y2-DC-1004-02); and with funding from
Hjartavernd (Icelandic Heart Association) and the Althingi (Icelandic
Parliament).
NR 30
TC 25
Z9 26
U1 1
U2 10
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 0002-0729
EI 1468-2834
J9 AGE AGEING
JI Age Ageing
PD JAN
PY 2014
VL 43
IS 1
BP 69
EP 76
DI 10.1093/ageing/aft122
PG 8
WC Geriatrics & Gerontology
SC Geriatrics & Gerontology
GA 271JZ
UT WOS:000328389200014
PM 23996030
ER
PT J
AU Gingold, JA
Simon, AE
Schoendorf, KC
AF Gingold, Janet A.
Simon, Alan E.
Schoendorf, Kenneth C.
TI Excess Screen Time in US Children: Association With Family Rules and
Alternative Activities
SO CLINICAL PEDIATRICS
LA English
DT Article
DE children; adolescents; screen time; media use; sedentary behavior;
physical activity; National Survey of Children's Health
ID PHYSICAL-ACTIVITY; WEIGHT STATUS; MEDIA USE; ADOLESCENT OVERWEIGHT;
CHILDHOOD OVERWEIGHT; SEDENTARY BEHAVIORS; TELEVISION USE;
DIETARY-INTAKE; MEAL PATTERNS; UNITED-STATES
AB We describe the association of screen time in excess of American Academy of Pediatrics recommendations (2 h/d) with family television-use policies and regular nonscreen activities among US school-aged children. Data from the 2007 National Survey of Children's Health were used. The sum of minutes spent on television, videos, video games, and recreational computer use was calculated for children 6 to 17 years old. Bivariate and multivariate logistic regression models were used to calculate relative odds of exceeding American Academy of Pediatrics guidelines and of heavy screen use (>4 h/d) for varying family media-use policies and frequency of alternative activities (physical activity and family meals). In all, 49% of school-aged children had screen time >2 h/d and 16% had screen time >4 h/d. Lower frequency of family meals, presence of TV in the bedroom, absence of rules about TV viewing, and less physical activity were associated with both >2 and >4 hours per day of screen time.
C1 [Gingold, Janet A.] Childrens Natl Med Ctr, Washington, DC 20010 USA.
[Simon, Alan E.; Schoendorf, Kenneth C.] Ctr Dis Control & Prevent, Natl Ctr Hlth Stat, Hyattsville, MD 20782 USA.
[Schoendorf, Kenneth C.] US PHS, Rockville, MD USA.
RP Gingold, JA (reprint author), Childrens Natl Med Ctr, Goldberg Ctr, 111 Michigan Ave NW, Washington, DC 20010 USA.
EM jgingold@cnmc.org
OI Gingold, Janet/0000-0001-7236-1575
NR 64
TC 9
Z9 9
U1 4
U2 24
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 0009-9228
EI 1938-2707
J9 CLIN PEDIATR
JI Clin. Pediatr.
PD JAN
PY 2014
VL 53
IS 1
BP 41
EP 50
DI 10.1177/0009922813498152
PG 10
WC Pediatrics
SC Pediatrics
GA 265ZI
UT WOS:000327990900008
PM 23922251
ER
PT J
AU Badaru, A
Klingensmith, GJ
Dabelea, D
Mayer-Davis, EJ
Dolan, L
Lawrence, JM
Marcovina, S
Beavers, D
Rodriguez, BL
Imperatore, G
Pihoker, C
AF Badaru, Angela
Klingensmith, Georgeanna J.
Dabelea, Dana
Mayer-Davis, Elizabeth J.
Dolan, Lawrence
Lawrence, Jean M.
Marcovina, Santica
Beavers, Daniel
Rodriguez, Beatriz L.
Imperatore, Giuseppina
Pihoker, Catherine
TI Correlates of Treatment Patterns Among Youth With Type 2 Diabetes
SO DIABETES CARE
LA English
DT Article
ID PEDIATRIC-PATIENTS; GLYCEMIC CONTROL; METFORMIN; MONOTHERAPY; CHILDREN;
FAILURE; ADOLESCENTS; MELLITUS; SEARCH; TRIAL
AB OBJECTIVETo describe treatment regimens in youth with type 2 diabetes and examine associations between regimens, demographic and clinical characteristics, and glycemic control.RESEARCH DESIGN AND METHODSThis report includes 474 youth with a clinical diagnosis of type 2 diabetes who completed a SEARCH for Diabetes in Youth study visit. Diabetes treatment regimen was categorized as lifestyle alone, metformin monotherapy, any oral hypoglycemic agent (OHA) other than metformin or two or more OHAs, insulin monotherapy, and insulin plus any OHA(s). Association of treatment with demographic and clinical characteristics (fasting C-peptide [FCP], diabetes duration, and self-monitoring of blood glucose [SMBG]), and A1C was assessed by (2) and ANOVA. Multiple linear regression models were used to evaluate independent associations of treatment regimens and A1C, adjusting for demographics, diabetes duration, FCP, and SMBG.RESULTSOver 50% of participants reported treatment with metformin alone or lifestyle. Of the autoantibody-negative youth, 40% were on metformin alone, while 33% were on insulin-containing regimens. Participants on metformin alone had a lower A1C (7.0 2.0%, 53 +/- 22 mmol/mol) than those on insulin alone (9.2 +/- 2.7%, 77 +/- 30 mmol/mol) or insulin plus OHA (8.6 +/- 2.6%, 70 +/- 28 mmol/mol) (P < 0.001). These differences remained significant after adjustment (7.5 +/- 0.3%, 58 +/- 3 mmol/mol; 9.1 +/- 0.4%, 76 +/- 4 mmol/mol; and 8.6 +/- 0.4%, 70 +/- 4 mmol/mol) (P < 0.001) and were more striking in those with diabetes for 2 years (7.9 +/- 2.8, 9.9 +/- 2.8, and 9.8 +/- 2.6%). Over one-half of those on insulin-containing therapies still experience treatment failure (A1C 8%, 64 mmol/mol).CONCLUSIONSApproximately half of youth with type 2 diabetes were managed with lifestyle or metformin alone and had better glycemic control than individuals using other therapies. Those with longer diabetes duration in particular commonly experienced treatment failures, and more effective management strategies are needed.
C1 [Badaru, Angela; Pihoker, Catherine] Univ Washington, Dept Pediat, Seattle, WA 98195 USA.
[Klingensmith, Georgeanna J.] Univ Colorado, Sch Med, Barbara Davis Ctr, Aurora, CO USA.
[Klingensmith, Georgeanna J.] Univ Colorado, Sch Med, Dept Pediat, Aurora, CO USA.
[Dabelea, Dana] Univ Colorado Denver, Colorado Sch Publ Hlth, Dept Epidemiol, Aurora, CO USA.
[Mayer-Davis, Elizabeth J.] Univ N Carolina, Dept Nutr, Chapel Hill, NC USA.
[Mayer-Davis, Elizabeth J.] Univ N Carolina, Dept Med, Chapel Hill, NC USA.
[Dolan, Lawrence] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati Childrens Hosp, Cincinnati, OH USA.
[Lawrence, Jean M.] Kaiser Permanente So Calif, Dept Res & Evaluat, Pasadena, CA 91101 USA.
[Marcovina, Santica] Univ Washington, Dept Med, Seattle, WA USA.
[Beavers, Daniel] Wake Forest Sch Med, Dept Biostat Sci, Winston Salem, NC USA.
[Rodriguez, Beatriz L.] Univ Hawaii Manoa, John A Burns Sch Med, Honolulu, HI 96822 USA.
[Imperatore, Giuseppina] Ctr Dis Control & Prevent, Div Diabet Translat, Atlanta, GA USA.
RP Pihoker, C (reprint author), Univ Washington, Dept Pediat, Seattle, WA 98195 USA.
EM catherine.pihoker@seattlechildrens.org
RI Beavers, Daniel/G-5338-2016
FU Centers for Disease Control and Prevention [00097, DP-05-069,
DP-10-001]; NIDDK; Kaiser Permanente Southern California [U48/CCU919219,
U01 DP000246, U18DP002714]; University of Colorado Denver
[U48/CCU819241-3, U01 DP000247, U18DP000247-06A1]; Kuakini Medical
Center [U58CCU919256, U01 DP000245]; Children's Hospital Medical Center
(Cincinnati) [U48/CCU519239, U01 DP000248, 1U18DP002709]; University of
North Carolina at Chapel Hill [U48/CCU419249, U01 DP000254,
U18DP002708-01]; University of Washington School of Medicine
[U58/CCU019235-4, U01 DP000244, U18DP002710-01]; Wake Forest University
School of Medicine [U48/CCU919219, U01 DP000250, 200-2010-35171];
National Institutes of Health [NIH]/National Center for Research
Resources [NCRR] [UL1RR029882]; Children's Hospital and Regional Medical
Center [M01RR00037]; Colorado Pediatric General Clinical Research Center
[M01 RR00069]; Barbara Davis Center at the University of Colorado Denver
[DERC NIH P30 DK57516]; Institutional Clinical and Translational Science
Award, NIH/NCRR, at the University of Cincinnati [1UL1RR026314-01]
FX SEARCH is funded by the Centers for Disease Control and Prevention (PA
numbers 00097, DP-05-069, and DP-10-001) and supported by the NIDDK.
Site contract numbers are as follows: Kaiser Permanente Southern
California (U48/CCU919219, U01 DP000246, and U18DP002714), University of
Colorado Denver (U48/CCU819241-3, U01 DP000247, and U18DP000247-06A1),
Kuakini Medical Center (U58CCU919256 and U01 DP000245), Children's
Hospital Medical Center (Cincinnati) (U48/CCU519239, U01 DP000248, and
1U18DP002709), University of North Carolina at Chapel Hill
(U48/CCU419249, U01 DP000254, and U18DP002708-01), University of
Washington School of Medicine (U58/CCU019235-4, U01 DP000244, and
U18DP002710-01), and Wake Forest University School of Medicine
(U48/CCU919219, U01 DP000250, and 200-2010-35171). The authors
acknowledge the involvement of General Clinical Research Centers at the
South Carolina Clinical & Translational Research Institute, the Medical
University of South Carolina (National Institutes of Health
[NIH]/National Center for Research Resources [NCRR] grant no.
UL1RR029882), the Children's Hospital and Regional Medical Center (grant
no. M01RR00037), the Colorado Pediatric General Clinical Research Center
(grant no. M01 RR00069), and the Barbara Davis Center at the University
of Colorado Denver (DERC NIH P30 DK57516); the Institutional Clinical
and Translational Science Award, NIH/NCRR, at the University of
Cincinnati (grant no. 1UL1RR026314-01); and the Children with Medical
Handicaps program managed by the Ohio Department of Health.
NR 19
TC 5
Z9 5
U1 0
U2 6
PU AMER DIABETES ASSOC
PI ALEXANDRIA
PA 1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA
SN 0149-5992
EI 1935-5548
J9 DIABETES CARE
JI Diabetes Care
PD JAN
PY 2014
VL 37
IS 1
BP 64
EP 72
DI 10.2337/dc13-1124
PG 9
WC Endocrinology & Metabolism
SC Endocrinology & Metabolism
GA 275KV
UT WOS:000328676000023
PM 24026554
ER
PT J
AU Chou, CF
Sherrod, CE
Zhang, XZ
Barker, LE
Bullard, KM
Crews, JE
Saaddine, JB
AF Chou, Chiu-Fang
Sherrod, Cheryl E.
Zhang, Xinzhi
Barker, Lawrence E.
Bullard, Kai McKeever
Crews, John E.
Saaddine, Jinan B.
TI Barriers to Eye Care Among People Aged 40 Years and Older With Diagnosed
Diabetes, 2006-2010
SO DIABETES CARE
LA English
DT Article
ID HEALTH-INSURANCE COVERAGE; ANGELES LATINO EYE; AFRICAN-AMERICANS; VISUAL
IMPAIRMENT; US ADULTS; VISION; RETINOPATHY; PREVALENCE; GUIDELINES;
SERVICES
AB OBJECTIVEWe examine barriers to receiving recommended eye care among people aged 40 years with diagnosed diabetes.RESEARCH DESIGN AND METHODSWe analyzed 2006-2010 Behavioral Risk Factor Surveillance System data from 22 states (n = 27,699). Respondents who had not sought eye care in the preceding 12 months were asked the main reason why. We categorized the reasons as cost/lack of insurance, no need, no eye doctor/travel/appointment, and other (meaning everything else). We used multinomial logistic regression to control for race/ethnicity, education, income, and other selected covariates.RESULTSAmong adults with diagnosed diabetes, nonadherence to the recommended annual eye examinations was 23.5%. The most commonly reported reasons for not receiving eye care in the preceding 12 months were no need and cost or lack of insurance (39.7 and 32.3%, respectively). Other reasons were no eye doctor, no transportation or could not get appointment (6.4%), and other (21.5%). After controlling for covariates, adults aged 40-64 years were more likely than those aged 65 years (relative risk ratio [RRR] = 2.79; 95% CI 2.01-3.89) and women were more likely than men (RRR = 2.33; 95% CI 1.75-3.14) to report cost or lack of insurance as their main reason. However, people aged 40-64 years were less likely than those aged 65 years to report no need (RRR = 0.51; 95% CI 0.39-0.67) as their main reason.CONCLUSIONSAddressing concerns about cost or lack of insurance for adults under 65 years and no perceived need among those 65 years and older could help improve eye care service utilization among people with diabetes.
C1 [Chou, Chiu-Fang; Zhang, Xinzhi; Barker, Lawrence E.; Bullard, Kai McKeever; Crews, John E.; Saaddine, Jinan B.] Ctr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USA.
[Sherrod, Cheryl E.] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Baltimore, MD USA.
RP Chou, CF (reprint author), Ctr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USA.
EM cchou@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 36
TC 5
Z9 5
U1 0
U2 6
PU AMER DIABETES ASSOC
PI ALEXANDRIA
PA 1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA
SN 0149-5992
EI 1935-5548
J9 DIABETES CARE
JI Diabetes Care
PD JAN
PY 2014
VL 37
IS 1
BP 180
EP 188
DI 10.2337/dc13-1507
PG 9
WC Endocrinology & Metabolism
SC Endocrinology & Metabolism
GA 275KV
UT WOS:000328676000038
PM 24009300
ER
PT J
AU de Ravello, L
Jones, SE
Tulloch, S
Taylor, M
Doshi, S
AF de Ravello, Lori
Jones, Sherry Everett
Tulloch, Scott
Taylor, Melanie
Doshi, Sonal
TI Substance Use and Sexual Risk Behaviors Among American Indian and Alaska
Native High School Students
SO JOURNAL OF SCHOOL HEALTH
LA English
DT Article
DE American Indian; Alaska Native; Indians; Native American; North America;
sexual behavior; substance use; Youth Risk Behavior Surveillance System
ID YOUTH; ADOLESCENTS
AB BACKGROUNDWe describe the prevalence of behaviors that put American Indian and Alaska Native (AI/AN) high school students at risk for teen pregnancy and sexually transmitted infections (STIs) and the relationships among race/ethnicity and these behaviors.
METHODSWe analyzed merged 2007 and 2009 data from the national Youth Risk Behavior Survey, a biennial, self-administered, school-based survey of US students in grades 9-12 (N=27,912). Prevalence estimates and logistic regression, controlling for sex and grade, were used to examine the associations between race/ethnicity, and substance use, and sexual risk behaviors.
RESULTSOf the 26 variables studied, the adjusted odds ratios (AOR) were higher among AI/AN than White students for 18 variables (ranging from 1.4 to 2.3), higher among AI/AN than Black students for 13 variables (ranging from 1.4 to 4.2), and higher among AI/AN than Hispanic students for 5 variables (ranging from 1.4 to 1.5). Odds were lower among AI/AN than Black students for many of the sexual risk-related behaviors.
CONCLUSIONSThe data suggest it is necessary to develop targeted, adolescent-specific interventions aimed at reducing behaviors that put AI/AN high school students at risk for teen pregnancy, STI/HIV, and other health conditions.
C1 [de Ravello, Lori] Ctr Dis Control & Prevent, Div Reprod Hlth, Atlanta, GA 30341 USA.
[Jones, Sherry Everett] Ctr Dis Control & Prevent, Div Adolescent, Atlanta, GA 30341 USA.
[Jones, Sherry Everett] Ctr Dis Control & Prevent, Sch Hlth, Atlanta, GA 30341 USA.
[Tulloch, Scott] Ctr Dis Control & Prevent, Div STD Prevent, Atlanta, GA 30333 USA.
[Taylor, Melanie] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
[Doshi, Sonal] Ctr Dis Control & Prevent, Off State Tribal Local & Territorial Support, Atlanta, GA 30341 USA.
RP de Ravello, L (reprint author), Ctr Dis Control & Prevent, Div Reprod Hlth, 4770 Buford Hwy NE,MS K22, Atlanta, GA 30341 USA.
EM leb8@cdc.gov; sce2@cdc.gov; sdt2@cdc.gov; mdt7@cdc.gov; srd5@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 34
TC 17
Z9 17
U1 2
U2 12
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0022-4391
EI 1746-1561
J9 J SCHOOL HEALTH
JI J. Sch. Health
PD JAN
PY 2014
VL 84
IS 1
BP 25
EP 32
DI 10.1111/josh.12114
PG 8
WC Education & Educational Research; Education, Scientific Disciplines;
Health Care Sciences & Services; Public, Environmental & Occupational
Health
SC Education & Educational Research; Health Care Sciences & Services;
Public, Environmental & Occupational Health
GA 269CH
UT WOS:000328217600004
PM 24320149
ER
PT J
AU Dooyema, CA
Copeland, D
Sinclair, JR
Shi, JR
Wilkins, M
Wells, E
Collins, J
AF Dooyema, Carrie A.
Copeland, Daphne
Sinclair, Julie R.
Shi, Jianrong
Wilkins, Melinda
Wells, Eden
Collins, Jim
TI Factors Influencing School Closure and Dismissal Decisions: Influenza A
(H1N1), Michigan 2009
SO JOURNAL OF SCHOOL HEALTH
LA English
DT Article
DE influenza; Michigan; non-pharmaceutical interventions; pandemic flu;
school closure policy
ID TRANSMISSION; COMMUNITY; OUTBREAK; ILLNESS
AB BACKGROUNDIn fall 2009, many US communities experienced school closures during the influenza A H1N1 pandemic (pH1N1) and the state of Michigan reported 567 closures. We conducted an investigation in Michigan to describe pH1N1-related school policies, practices, and identify factors related to school closures.
METHODSWe distributed an online survey to all Michigan K-12 school principals. Descriptive statistics and chi-square tests summarize school policies, practices, adherence to government guidelines, and differences between schools that closed and those that remained open during the pandemic.
RESULTSOf 4441 traditional K-12 Michigan schools, 937 (21%) principals responded to our survey representing approximately 374,000 students and 17,700 teachers. The majority (88%) of schools had influenza preparedness plans and followed government school influenza guidelines. Among respondents, 15% (137/937) of schools closed in fall 2009 with high absenteeism as the primary reason for closure. Schools that closed reported significant illness in their school, had <300 students, and had invested substantial resources preparing and responding to influenza.
CONCLUSIONSAdherence to government guidelines for schools appears high in Michigan. Closures occurred in schools that reported significant illness and were likely motivated by excessive absenteeism. Understanding factors related to closures during pH1N1 may inform future pandemic preparedness efforts.
C1 [Dooyema, Carrie A.] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Atlanta, GA 30341 USA.
[Copeland, Daphne; Shi, Jianrong] Ctr Dis Control & Prevent, Div Global Migrat & Quarantine, Atlanta, GA 30333 USA.
[Sinclair, Julie R.] Ctr Dis Control & Prevent, Div Global Migrat & Quarantine, Philadelphia, PA 19153 USA.
[Wilkins, Melinda; Wells, Eden; Collins, Jim] Michigan Dept Community Hlth, Bur Epidemiol, Div Communicable Dis, Lansing, MI 48913 USA.
RP Dooyema, CA (reprint author), Ctr Dis Control & Prevent, 4770 Buford Highway,MS K-26, Chamblee, GA 30341 USA.
EM igb7@cdc.gov; dcopeland@cdc.gov; bwg5@cdc.gov; hku3@cdc.gov;
wilkinsm@msu.edu; ewells@umich.edu; collinsj12@michigan.gov
NR 16
TC 6
Z9 6
U1 4
U2 12
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0022-4391
EI 1746-1561
J9 J SCHOOL HEALTH
JI J. Sch. Health
PD JAN
PY 2014
VL 84
IS 1
BP 56
EP 62
DI 10.1111/josh.12113
PG 7
WC Education & Educational Research; Education, Scientific Disciplines;
Health Care Sciences & Services; Public, Environmental & Occupational
Health
SC Education & Educational Research; Health Care Sciences & Services;
Public, Environmental & Occupational Health
GA 269CH
UT WOS:000328217600008
PM 24320153
ER
PT B
AU Ballard, DJ
Fleming, NS
AF Ballard, David J.
Fleming, Neil S.
BE Ballard, DJ
TI Achieving STEEEP Health Care Introduction
SO ACHIEVING STEEEP HEALTH CARE
LA English
DT Editorial Material; Book Chapter
C1 [Ballard, David J.] BHCS, Dallas, TX USA.
[Ballard, David J.] BHCS Inst Hlth Care Res & Improvement, Dallas, TX USA.
[Ballard, David J.] BHCS STEEEP Safe Timely Effect Efficient Equitabl, Dallas, TX USA.
[Ballard, David J.] Mayo Clin & Mayo Grad Sch Med, Rochester, MN USA.
[Ballard, David J.] Univ Virginia, Sch Med, Charlottesville, VA 22903 USA.
[Ballard, David J.] Emory Univ, Sch Med, Med, Atlanta, GA 30322 USA.
[Ballard, David J.] Emory Univ, Rollins Sch Publ Hlth, Epidemiol, Atlanta, GA 30322 USA.
[Ballard, David J.] Mayo Sect Hlth Serv Evaluat, Rochester, MN USA.
[Ballard, David J.] Kerr L White Inst Hlth Serv Res, Rockville, MD USA.
[Ballard, David J.] Int Soc Qual Hlth Care, Rockville, MD USA.
[Ballard, David J.] AHRQ, Hlth Care Qual & Effectiveness Res Study Sect, Rockville, MD USA.
[Ballard, David J.] Univ N Carolina, Chapel Hill, NC 27515 USA.
[Fleming, Neil S.] BHCS STEEEP Global Inst, Dallas, TX USA.
[Fleming, Neil S.] Ctr Dis Control, Natl Ctr Hlth Stat, Atlanta, GA 30333 USA.
RP Ballard, DJ (reprint author), AHRQ, Ctr Educ & Res Therapeut Steering Comm, Rockville, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU CRC PRESS-TAYLOR & FRANCIS GROUP
PI BOCA RATON
PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA
BN 978-1-4665-6538-8; 978-1-4665-6537-1
PY 2014
BP XXIII
EP XXIX
PG 7
WC Health Care Sciences & Services; Health Policy & Services
SC Health Care Sciences & Services
GA BE6PM
UT WOS:000374503500003
ER
PT B
AU Leonard, BM
Shutts, C
Fleming, NS
AF Leonard, Bradley M.
Shutts, Christopher
Fleming, Neil S.
BE Ballard, DJ
TI STEEEP Academy
SO ACHIEVING STEEEP HEALTH CARE
LA English
DT Article; Book Chapter
ID COMMUNITY HOSPITALS; TRIAL
C1 [Leonard, Bradley M.; Fleming, Neil S.] Baylor Hlth Care Syst, STEEEP Global Inst, Dallas, TX USA.
[Shutts, Christopher] Baylor Hlth Care Syst, STEEEP Acad, Dallas, TX USA.
[Fleming, Neil S.] Ctr Dis Control, Natl Ctr Hlth Stat, Atlanta, GA 30333 USA.
RP Leonard, BM (reprint author), Baylor Hlth Care Syst, STEEEP Global Inst, Dallas, TX USA.
NR 7
TC 0
Z9 0
U1 0
U2 0
PU CRC PRESS-TAYLOR & FRANCIS GROUP
PI BOCA RATON
PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA
BN 978-1-4665-6538-8; 978-1-4665-6537-1
PY 2014
BP 51
EP 61
PG 11
WC Health Care Sciences & Services; Health Policy & Services
SC Health Care Sciences & Services
GA BE6PM
UT WOS:000374503500011
ER
PT B
AU Fleming, NS
Masica, A
McCarthy, I
AF Fleming, Neil S.
Masica, Andrew
McCarthy, Ian
BE Ballard, DJ
TI Evaluation of Clinical, Economic, and Financial Outcomes
SO ACHIEVING STEEEP HEALTH CARE
LA English
DT Article; Book Chapter
ID CARE; HEALTH; COSTS
C1 [Fleming, Neil S.] BHCS STEEEP Global Inst, Dallas, TX 75246 USA.
[Fleming, Neil S.] Ctr Dis Control, Natl Ctr Hlth Stat, Atlanta, GA 30333 USA.
[Masica, Andrew] Baylor Hlth Care Syst, Clin Innovat, Dallas, TX USA.
[McCarthy, Ian] Baylor Hlth Care Syst, Hlth Econ, Dallas, TX USA.
RP Fleming, NS (reprint author), BHCS STEEEP Global Inst, Dallas, TX 75246 USA.
NR 10
TC 0
Z9 0
U1 0
U2 0
PU CRC PRESS-TAYLOR & FRANCIS GROUP
PI BOCA RATON
PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA
BN 978-1-4665-6538-8; 978-1-4665-6537-1
PY 2014
BP 83
EP 90
PG 8
WC Health Care Sciences & Services; Health Policy & Services
SC Health Care Sciences & Services
GA BE6PM
UT WOS:000374503500015
ER
PT B
AU Fleming, NS
Ballard, DJ
AF Fleming, Neil S.
Ballard, David J.
BE Ballard, DJ
TI Achieving STEEEP Health Care Conclusion
SO ACHIEVING STEEEP HEALTH CARE
LA English
DT Editorial Material; Book Chapter
C1 [Fleming, Neil S.] BHCS STEEEP Global Inst, Dallas, TX 75206 USA.
[Fleming, Neil S.] BHCS, Dallas, TX USA.
[Fleming, Neil S.] Ctr Dis Control, Natl Ctr Hlth Stat, Atlanta, GA 30333 USA.
[Ballard, David J.] BHCS, Dallas, TX USA.
[Ballard, David J.] BHCS Inst Hlth Care Res & Improvement, Dallas, TX USA.
[Ballard, David J.] Global Inst, BHCS STEEEP Safe Timely Effect Efficient Equitabl, Dallas, TX USA.
[Ballard, David J.] Mayo Clin & Mayo Grad Sch Med, Rochester, MN USA.
[Ballard, David J.] Univ Virginia, Sch Med, Charlottesville, VA 22903 USA.
[Ballard, David J.] Emory Univ, Sch Med, Med, Atlanta, GA 30322 USA.
[Ballard, David J.] Emory Univ, Rollins Sch Publ Hlth, Epidemiol, Atlanta, GA 30322 USA.
[Ballard, David J.] Mayo Sect Hlth Serv Evaluat, Rochester, MN USA.
[Ballard, David J.] Kerr L White Inst Hlth Serv Res, Augusta, GA USA.
[Ballard, David J.] Int Soc Qual Hlth Care, Melbourne, Vic, Australia.
[Ballard, David J.] Agcy Healthcare Res & Qual, Hlth Care Qual & Effectiveness Res Study Sect, Rockville, MD USA.
RP Fleming, NS (reprint author), BHCS STEEEP Global Inst, Dallas, TX 75206 USA.
NR 6
TC 0
Z9 0
U1 0
U2 0
PU CRC PRESS-TAYLOR & FRANCIS GROUP
PI BOCA RATON
PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA
BN 978-1-4665-6538-8; 978-1-4665-6537-1
PY 2014
BP 237
EP 242
PG 6
WC Health Care Sciences & Services; Health Policy & Services
SC Health Care Sciences & Services
GA BE6PM
UT WOS:000374503500032
ER
PT J
AU Anjum, H
Wunderink, RG
Balk, R
Waterer, GW
Grace, B
Tulaimat, A
Self, WH
Grijalva, C
Courtney, M
Anderson, E
Jain, S
Bramley, A
Fakhran, S
AF Anjum, H.
Wunderink, R. G.
Balk, R.
Waterer, G. W.
Grace, B.
Tulaimat, A.
Self, W. H.
Grijalva, C.
Courtney, M.
Anderson, E.
Jain, S.
Bramley, A.
Fakhran, S.
TI Outcomes Of Pneumonia Hospitalizations Among Adults With And Without
Hyperglycemia And Diabetes Mellitus: Preliminary Results From The
Centers For Disease Control And Prevention Etiology Of Pneumonia In The
Community (epic) Study
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Anjum, H.; Tulaimat, A.; Fakhran, S.] John H Stroger Jr Hosp Cook Cty, Chicago, IL USA.
[Wunderink, R. G.; Grace, B.; Courtney, M.] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA.
[Balk, R.] Rush Univ, Med Ctr, Chicago, IL 60612 USA.
[Waterer, G. W.] Univ Western Australia, Perth, WA, Australia.
[Self, W. H.] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA.
[Grijalva, C.] Vanderbilt Univ, Med Ctr, Nashville, TN USA.
[Anderson, E.] Emory Univ, Med Ctr, Atlanta, GA 30322 USA.
[Jain, S.; Bramley, A.] Ctr Dis Control & Prevent, Nat Ctr Immunizat & Resp Dis, Atlanta, GA USA.
EM hanjum77@gmail.com
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A6520
PG 2
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838206318
ER
PT J
AU Beavers, SF
Mirabelli, MC
Chatterjee, A
AF Beavers, S. F.
Mirabelli, M. C.
Chatterjee, A.
TI Asthma Control And Exacerbations Among Adults With Diagnoses Of Asthma
And COPD
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Beavers, S. F.; Mirabelli, M. C.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Chatterjee, A.] Wake Forest Univ, Sch Med, Winston Salem, NC 27109 USA.
EM fgx5@cdc.gov
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A4596
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838204089
ER
PT J
AU Brust, JCM
Shah, NS
Mthiyane, T
Petersen, L
Ning, Y
Allana, S
Magee, M
Master, I
Gandhi, NR
AF Brust, J. C. M.
Shah, N. S.
Mthiyane, T.
Petersen, L.
Ning, Y.
Allana, S.
Magee, M.
Master, I.
Gandhi, N. R.
TI Novel Grading Scheme To Determine Severity Of Hearing Loss In Patients
Treated For Mdr-Tb
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Brust, J. C. M.; Ning, Y.] Montefiore Med Ctr, Bronx, NY 10467 USA.
[Brust, J. C. M.; Ning, Y.] Albert Einstein Coll Med, Bronx, NY 10467 USA.
[Shah, N. S.] US Ctr Dis Control & Prevent, Atlanta, GA USA.
[Mthiyane, T.] South African Med Res Council, Durban, South Africa.
[Petersen, L.] Univ Cape Town, Cape Town, South Africa.
[Allana, S.; Magee, M.; Gandhi, N. R.] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA.
[Master, I.] King George V King Dinuzulu Hosp Complex, Durban, South Africa.
EM jcmbrust@gmail.com
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A2562
PG 2
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838201720
ER
PT J
AU Carlson, EK
Miller, TL
Katz, DJ
Vemulapalli, A
Fa, A
Rohrback, AC
Gallups, JS
AF Carlson, E. K.
Miller, T. L.
Katz, D. J.
Vemulapalli, A.
Fa, A.
Rohrback, A. C.
Gallups, J. S.
TI Practical Economic Evaluation In The Local Setting: A Web-Based Tool To
Guide Latent Tuberculosis Infection (ltbi) Screening And Treatment
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Carlson, E. K.; Miller, T. L.; Vemulapalli, A.; Fa, A.; Rohrback, A. C.] Univ North Texas Hlth Sci Ctr, Ft Worth, TX USA.
[Katz, D. J.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Gallups, J. S.] Tarrant Cty Publ Hlth, Ft Worth, TX USA.
EM erin.carlson@unthsc.edu
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A3207
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838202483
ER
PT J
AU Colton, M
Hsu, J
Chew, G
Brugge, D
Yip, F
Sircar, K
Ryan, PH
Sandel, M
Adamkiewicz, G
AF Colton, M.
Hsu, J.
Chew, G.
Brugge, D.
Yip, F.
Sircar, K.
Ryan, P. H.
Sandel, M.
Adamkiewicz, G.
TI Characterizing Asthma Morbidity And The Indoor Environment Of
Low-Income, Chinese-American Children In The Green Housing Study
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Colton, M.; Adamkiewicz, G.] Harvard Sch Publ Hlth, Boston, MA USA.
[Hsu, J.] Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA USA.
[Chew, G.; Yip, F.; Sircar, K.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Brugge, D.] Tufts Univ, Sch Med, Boston, MA 02111 USA.
[Ryan, P. H.] Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH 45229 USA.
[Sandel, M.] Boston Univ, Sch Med, Boston, MA 02118 USA.
EM mcolton@mail.harvard.edu
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A5087
PG 2
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838204571
ER
PT J
AU Cummings, KJ
Virji, MA
Park, JY
Carey, B
Trapnell, BC
Healey, T
Armstrong, JL
Kreiss, K
AF Cummings, K. J.
Virji, M. A.
Park, J. Y.
Carey, B.
Trapnell, B. C.
Healey, T.
Armstrong, J. L.
Kreiss, K.
TI Relationship Between Respiratory Health And Exposure Indices Among
Workers At An Indium-Tin Oxide (ito) Production Facility
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Cummings, K. J.; Virji, M. A.; Park, J. Y.; Armstrong, J. L.; Kreiss, K.] NIOSH, CDC, Morgantown, WV USA.
[Cummings, K. J.; Carey, B.; Trapnell, B. C.] Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH 45229 USA.
[Healey, T.] Brown Univ, Warren Alpert Med Sch, Providence, RI 02912 USA.
EM cvx5@cdc.gov
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A3174
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838202451
ER
PT J
AU Ford, ES
AF Ford, E. S.
TI Lung Function, Vitamin D Concentrations, And Mortality In United States
Adults
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Ford, E. S.] Ctr Dis Control & Prevent, Atlanta, GA USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A3775
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838203147
ER
PT J
AU Girard, TD
Edwards, KM
Self, WH
Grijalva, CG
Zhu, Y
Williams, DJ
Jain, S
Jackson, JC
AF Girard, T. D.
Edwards, K. M.
Self, W. H.
Grijalva, C. G.
Zhu, Y.
Williams, D. J.
Jain, S.
Jackson, J. C.
TI Long-Term Cognitive Outcomes After Hospitalization For
Community-Acquired Pneumonia (cogcap)
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Girard, T. D.; Grijalva, C. G.; Jackson, J. C.] Vanderbilt Univ Sch Med, Nashville, TN USA.
[Girard, T. D.; Grijalva, C. G.; Jackson, J. C.] VA Med Ctr, Nashville, TN USA.
[Edwards, K. M.; Self, W. H.; Zhu, Y.; Williams, D. J.] Vanderbilt Univ Sch Med, Nashville, TN USA.
[Jain, S.] Ctr Dis Control & Prevent, Atlanta, GA USA.
EM timothy.girard@vanderbilt.edu
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A6525
PG 2
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838206323
ER
PT J
AU Henneberger, PK
Cox-Ganser, J
Moore, VC
Burge, CB
Liang, X
Burge, PS
AF Henneberger, P. K.
Cox-Ganser, J.
Moore, V. C.
Burge, C. B.
Liang, X.
Burge, P. S.
TI Can Serial Fev1 Identify Work-Related Asthma Cases Missed By Serial Peak
Expiratory Flow?
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Henneberger, P. K.; Cox-Ganser, J.; Liang, X.] NIOSH, CDC, Morgantown, WV USA.
[Moore, V. C.; Burge, C. B.; Burge, P. S.] Birmingham Heartlands Hosp, Birmingham, W Midlands, England.
EM pkh0@cdc.gov
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A4594
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838204087
ER
PT J
AU Jayakumar, A
Everett, CK
Benator, D
Davis, JL
Alland, D
Heilig, C
Weiner, M
Kerrigan, A
Zamudio, C
Goldberg, S
Whitworth, WC
Nahid, P
AF Jayakumar, A.
Everett, C. K.
Benator, D.
Davis, J. L.
Alland, D.
Heilig, C.
Weiner, M.
Kerrigan, A.
Zamudio, C.
Goldberg, S.
Whitworth, W. C.
Nahid, P.
TI Quantitative Xpert Mtb/rif To Assess Tuberculosis Treatment Response:
Timing To Predict Eight Week Culture Conversion
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Jayakumar, A.; Everett, C. K.; Davis, J. L.; Nahid, P.] Univ Calif San Francisco, San Francisco, CA 94143 USA.
[Benator, D.] Washington DC VA Med Ctr, Washington, DC USA.
[Alland, D.] Rutgers New Jersey Med Sch, Newark, NJ USA.
[Heilig, C.; Goldberg, S.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Weiner, M.] Univ Texas Hlth Sci Ctr San Antonio, San Antonio, TX 78229 USA.
[Kerrigan, A.] Vanderbilt Univ, Med Ctr, Nashville, TN USA.
[Zamudio, C.] Univ Peruana Cayetano Heredia, Lima, Peru.
[Whitworth, W. C.] CDC, Atlanta, GA 30333 USA.
EM archana.jayakumar@ucsf.edu
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A2551
PG 2
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838201710
ER
PT J
AU Larson, T
Antao, VC
AF Larson, T.
Antao, V. C.
TI Localized Pleural Thickening Of Upper Lung Zones
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Larson, T.; Antao, V. C.] ATSDR, Atlanta, GA USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A3160
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838202437
ER
PT J
AU Miller, TL
Wilson, FE
Pang, W
Beavers, S
Hoger, S
Sharnprapai, S
Pagaoa, M
Katz, D
Weis, SE
AF Miller, T. L.
Wilson, F. E.
Pang, W.
Beavers, S.
Hoger, S.
Sharnprapai, S.
Pagaoa, M.
Katz, D.
Weis, S. E.
TI Mortality Hazard And Survival After Tuberculosis Treatment
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Miller, T. L.; Weis, S. E.] Univ North Texas Hlth Sci Ctr, Ft Worth, TX USA.
[Wilson, F. E.] Univ Nebraska, Omaha, NE 68182 USA.
[Pang, W.] Univ Washington, Seattle, WA 98195 USA.
[Beavers, S.; Pagaoa, M.; Katz, D.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Hoger, S.] Tarleton State Univ, Ft Worth, TX USA.
[Sharnprapai, S.] Massachusetts Dept Publ Hlth, Jamaica, NJ USA.
EM thaddeus.miller@unthsc.edu
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A5771
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838205391
ER
PT J
AU Mirabelli, MC
Beavers, SF
Chatterjee, AB
AF Mirabelli, M. C.
Beavers, S. F.
Chatterjee, A. B.
TI Active Asthma, Smoking Status, And The Prevalence Of COPD Among Adults
With A History Of Asthma
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Mirabelli, M. C.; Beavers, S. F.] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Atlanta, GA USA.
[Chatterjee, A. B.] Wake Forest Sch Med, Winston Salem, NC USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A5934
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838205554
ER
PT J
AU Mirabelli, MC
Beavers, SF
Flanders, WD
Chatterjee, AB
AF Mirabelli, M. C.
Beavers, S. F.
Flanders, W. D.
Chatterjee, A. B.
TI Five-Year Reliability Of Self-Reported Asthma History Among Adult Study
Participants
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Mirabelli, M. C.] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Atlanta, GA USA.
[Flanders, W. D.] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA.
[Chatterjee, A. B.] Wake Forest Sch Med, Winston Salem, NC USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A2303
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838201462
ER
PT J
AU Peisl, A
Doney, B
Hoffman, EA
Graziani, M
Kullman, G
Kaufman, JD
Burchfiel, C
Donohue, KM
Stukovsky, KH
Fujishiro, K
Barr, RG
AF Peisl, A.
Doney, B.
Hoffman, E. A.
Graziani, M.
Kullman, G.
Kaufman, J. D.
Burchfiel, C.
Donohue, K. M.
Stukovsky, K. Hinckley
Fujishiro, K.
Barr, R. G.
TI Occupational Risk Factors For Percent Emphysema On Computed Tomography
In The Multi-Ethnic Study Of Atherosclerosis
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Peisl, A.; Donohue, K. M.; Barr, R. G.] Columbia Univ, New York, NY USA.
[Doney, B.; Graziani, M.; Burchfiel, C.] NIOSH, Morgantown, WV USA.
[Hoffman, E. A.] Univ Iowa, Iowa City, IA USA.
[Kullman, G.] IH Consulting LLC, Morgantown, WV USA.
[Kaufman, J. D.; Stukovsky, K. Hinckley] Univ Washington, Seattle, WA 98195 USA.
[Fujishiro, K.] NIOSH, Cincinnati, OH 45226 USA.
EM acp2173@columbia.edu
NR 0
TC 1
Z9 1
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A5099
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838204583
ER
PT J
AU Pinheiro, GA
Henley, S
Larson, T
Antao, VC
AF Pinheiro, G. A.
Henley, S.
Larson, T.
Antao, V. C.
TI Association Between Asbestos Consumption And Pleural Mesothelioma
Incidence In The Usa
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Pinheiro, G. A.; Larson, T.; Antao, V. C.] Agcy Tox Subst & Dis Registry, Atlanta, GA USA.
[Henley, S.] Ctr Dis Control & Prevent, Atlanta, GA USA.
EM ghp6@cdc.gov
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A5770
PG 2
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838205390
ER
PT J
AU Pleasants, RA
Heidari, K
Wheaton, A
Ohar, JA
Strange, CB
Mannino, DM
Croft, J
Liao, W
Kraft, M
AF Pleasants, R. A.
Heidari, K.
Wheaton, A.
Ohar, J. A.
Strange, C. B.
Mannino, D. M.
Croft, J.
Liao, W.
Kraft, M.
TI Adults At Risk For COPD - Use Of The Behavioral Risk Factor Surveillance
System
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Pleasants, R. A.; Kraft, M.] Duke Univ, Med Ctr, Durham, NC USA.
[Heidari, K.] South Carolina Dept Environm Hlth Control, Columbia, SC USA.
[Wheaton, A.; Croft, J.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Ohar, J. A.] Wake Forest Univ, Bowman Gray Sch Med, Winston Salem, NC USA.
[Strange, C. B.] Med Univ South Carolina, Charleston, SC USA.
[Mannino, D. M.] Univ Kentucky, Lexington, KY USA.
[Liao, W.] NC COPD Taskforce, Cary, NC USA.
EM roy.pleasants@duke.edu
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A5957
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838205577
ER
PT J
AU Pleasants, RA
Heidari, K
Wheaton, A
Ohar, JA
Strange, CB
Mannino, DM
Croft, J
Liao, W
Kraft, M
AF Pleasants, R. A.
Heidari, K.
Wheaton, A.
Ohar, J. A.
Strange, C. B.
Mannino, D. M.
Croft, J.
Liao, W.
Kraft, M.
TI Use Of The Behavioral Risk Factor Surveillance System To Describe
Comorbidities And Health Impairment In Adults At High-Risk For COPD
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Pleasants, R. A.] Duke Univ, Med Ctr, Durham, NC USA.
[Heidari, K.] South Carolina Dept Environm Hlth Control, Columbia, SC USA.
[Wheaton, A.; Croft, J.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Ohar, J. A.] Wake Forest Univ, Bowman Gray Sch Med, Winston Salem, NC USA.
[Strange, C. B.] Med Univ South Carolina, Charleston, SC USA.
[Mannino, D. M.] Univ Kentucky, Coll Publ Hlth, Lexington, KY USA.
[Liao, W.] NC COPD Taskforce, Cary, NC USA.
[Kraft, M.] Duke Univ, Med Ctr, Dept Pulm & Crit Care Med, Durham, NC 27706 USA.
EM roy.pleasants@duke.edu
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A5817
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838205437
ER
PT J
AU Reddy, D
Winter, M
Moro, R
Feng, PJ
Goldberg, S
Saukkonen, JJ
AF Reddy, D.
Winter, M.
Moro, R.
Feng, P. -J.
Goldberg, S.
Saukkonen, J. J.
TI Time-Based Analysis For Alanine Transaminase Monitoring To Detect
Hepatotoxicity During Tuberculosis Treatment
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Reddy, D.; Saukkonen, J. J.] Boston Univ, Boston, MA 02215 USA.
[Winter, M.] Boston Univ, Sch Publ Hlth, Boston, MA USA.
[Moro, R.; Feng, P. -J.; Goldberg, S.] CDC, Atlanta, GA 30333 USA.
EM divya.reddy@bmc.org
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A3202
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838202478
ER
PT J
AU Soyseth, V
Bakke, B
Henneberger, PK
Kongerud, J
AF Soyseth, V.
Bakke, B.
Henneberger, P. K.
Kongerud, J.
TI Accelerated Annual Decline In Fev1 Among Norwegian Aluminum Workers
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Soyseth, V.] Akershus Univ Hosp, Lorenskog, Norway.
[Soyseth, V.; Bakke, B.] Natl Inst Occupat Hlth, Oslo, Norway.
[Henneberger, P. K.] NIOSH, CDC, Morgantown, WV USA.
[Kongerud, J.] Univ Oslo, Oslo, Norway.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A5100
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838204584
ER
PT J
AU Tam, EK
Sircar, K
Miike, R
Yip, F
Divinksi, T
AF Tam, E. K.
Sircar, K.
Miike, R.
Yip, F.
Divinksi, T.
TI Is Vog Exposure Associated With Airway Obstruction In Hawaii Island
Schoolchildren?
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Tam, E. K.; Miike, R.; Divinksi, T.] Univ Hawaii, Honolulu, HI 96822 USA.
[Sircar, K.; Yip, F.] Ctr Dis Control & Prevent, Atlanta, GA USA.
EM tameliza@hawaii.edu
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A2312
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838201471
ER
PT J
AU Volkmann, T
Oeltmann, J
Moonan, P
Miramontes, R
AF Volkmann, T.
Oeltmann, J.
Moonan, P.
Miramontes, R.
TI Tuberculosis And Excess Alcohol Use In The United States, 1997-2012
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Volkmann, T.; Oeltmann, J.; Moonan, P.; Miramontes, R.] CDC, Atlanta, GA 30333 USA.
EM xdh4@cdc.gov
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A3210
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838202486
ER
PT J
AU Waterer, GW
Self, WH
Girard, TD
Trabue, C
McNabb, P
Courtney, DM
Anderson, E
Fakhran, S
Balk, R
Grijalva, CG
Bramley, A
Jain, S
AF Waterer, G. W.
Self, W. H.
Girard, T. D.
Trabue, C.
McNabb, P.
Courtney, D. M.
Anderson, E.
Fakhran, S.
Balk, R.
Grijalva, C. G.
Bramley, A.
Jain, S.
TI Analysis Of Adult Inpatient Deaths In The Cdc-Etiology Of Pneumonia In
The Community (epic) Study: Implications For Community-Acquired
Pneumonia (cap) Quality Of Care (qoc) Metrics
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Waterer, G. W.] Univ Western Australia, Perth, WA, Australia.
[Self, W. H.] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA.
[Girard, T. D.; Grijalva, C. G.] Vanderbilt Univ, Med Ctr, Nashville, TN USA.
[Trabue, C.; McNabb, P.] Nashville Baptist Hosp, Nashville, TN USA.
[Courtney, D. M.] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA.
[Anderson, E.] Emory Univ, Atlanta, GA 30322 USA.
[Fakhran, S.] John H Stroger Jr Hosp Cook Cty, Chicago, IL USA.
[Balk, R.] Rush Univ, Med Ctr, Chicago, IL 60612 USA.
[Bramley, A.; Jain, S.] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Atlanta, GA USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A6518
PG 2
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838206316
ER
PT J
AU White, GE
Mazurek, JM
Storey, E
AF White, G. E.
Mazurek, J. M.
Storey, E.
TI The Proportion Of Employed Adults With Asthma Who Have Frequent
Workplace Exposures
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [White, G. E.; Mazurek, J. M.; Storey, E.] NIOSH, CDC, Morgantown, WV USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A6494
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838206293
ER
PT J
AU Wunderink, RG
Self, WH
Waterer, GW
Anderson, E
Balk, R
Fakhran, S
Courtney, D
Qi, C
Williams, D
Zhu, Y
Hicks, L
Whitney, CG
Moore, MR
Carvalho, MDG
Bramley, A
Jain, S
Edwards, K
Grijalva, CG
AF Wunderink, R. G.
Self, W. H.
Waterer, G. W.
Anderson, E.
Balk, R.
Fakhran, S.
Courtney, D.
Qi, C.
Williams, D.
Zhu, Y.
Hicks, L.
Whitney, C. G.
Moore, M. R.
Carvalho, M. D. G.
Bramley, A.
Jain, S.
Edwards, K.
Grijalva, C. G.
TI Occult Pneumococcal Community-Acquired Pneumonia (cap) In The Cdc
Etiology Of Pneumonia In The Community (epic) Study Detected By
Serotype-Specific Urinary Antigen Detection (ssuad)
SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
C1 [Wunderink, R. G.; Courtney, D.; Qi, C.] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA.
[Self, W. H.; Grijalva, C. G.] Vanderbilt Univ, Nashville, TN 37235 USA.
[Waterer, G. W.] Univ Western Australia, Perth, WA, Australia.
[Anderson, E.] Emory Univ, Atlanta, GA 30322 USA.
[Balk, R.] Rush Univ, Med Ctr, Chicago, IL 60612 USA.
[Fakhran, S.] John H Stroger Jr Hosp Cook Cty, Chicago, IL USA.
[Williams, D.; Zhu, Y.; Edwards, K.] Vanderbilt Univ, Nashville, IL USA.
[Hicks, L.; Whitney, C. G.; Moore, M. R.; Carvalho, M. D. G.; Bramley, A.; Jain, S.] Ctr Dis Control & Prevent, Atlanta, GA USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER THORACIC SOC
PI NEW YORK
PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA
SN 1073-449X
EI 1535-4970
J9 AM J RESP CRIT CARE
JI Am. J. Respir. Crit. Care Med.
PY 2014
VL 189
MA A4639
PG 1
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA V45TF
UT WOS:000209838204131
ER
PT J
AU Cummings, KJ
McCague, AB
Kreiss, K
AF Cummings, Kristin J.
McCague, Anna-Binney
Kreiss, Kathleen
TI Nonmalignant Respiratory Disease Mortality in Styrene-Exposed Workers
SO EPIDEMIOLOGY
LA English
DT Letter
ID REINFORCED-PLASTICS; INDUSTRY
C1 [Cummings, Kristin J.; McCague, Anna-Binney; Kreiss, Kathleen] NIOSH, Div Resp Dis Studies, Ctr Dis Control & Prevent, Morgantown, WV 26505 USA.
RP Cummings, KJ (reprint author), NIOSH, Div Resp Dis Studies, Ctr Dis Control & Prevent, Morgantown, WV 26505 USA.
EM kcummings@cdc.gov
FU Intramural NIH HHS
NR 5
TC 4
Z9 4
U1 1
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1044-3983
EI 1531-5487
J9 EPIDEMIOLOGY
JI Epidemiology
PD JAN
PY 2014
VL 25
IS 1
BP 160
EP 161
DI 10.1097/EDE.0b013e3182a70b0f
PG 2
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 268XW
UT WOS:000328205200032
PM 24296936
ER
PT B
AU Astrovskaya, I
Mancuso, N
Tork, B
Mangul, S
Artyomenko, A
Skums, P
Ganova-Raeva, L
Mandoiu, I
Zelikovsky, A
AF Astrovskaya, Irina
Mancuso, Nicholas
Tork, Bassam
Mangul, Serghei
Artyomenko, Alex
Skums, Pavel
Ganova-Raeva, Lilia
Mandoiu, Ion
Zelikovsky, Alex
BE Poptsova, MS
TI Inferring Viral Quasispecies Spectra from Shotgun and Amplicon
Next-generation Sequencing Reads
SO GENOME ANALYSIS: CURRENT PROCEDURES AND APPLICATIONS
LA English
DT Article; Book Chapter
ID ERROR-CORRECTION; RNA VIRUSES; HIGH-THROUGHPUT; IN-VIVO; RECONSTRUCTION;
TECHNOLOGIES; MUTATIONS; VACCINE; DESIGN; HIV-1
AB Many clinically relevant viruses, including hepatitis C virus (HCV) and human immunodeficiency virus (HIV), exhibit high genomic diversity within infected hosts which may explain the failure of vaccines and resistance to existing antiviral therapies. Characterizing the viral population infecting a host requires reconstructing all coexisting (related, but non-identical) viral variants, referred to as quasispecies, and inferring their relative abundances. Next-generation sequencing is a promising approach for characterizing viral diversity due to its ability to generate a large number of reads at a low cost. However, standard assembly software was originally designed for a single genome assembly and cannot be used to assemble multiple closely related quasispecies sequences and estimate their abundances. In this chapter, we focus on the problem of reconstructing viral quasispecies populations from next-generation sequencing reads produced by two most commonly used strategies: the shotgun sequencing and the sequencing of partially overlapping PCR amplicons. We discuss computational challenges associated with each strategy and review existing approaches to quasispecies reconstruction with focus on two state-of-the-art software tools - Viral Spectrum Assembler (ViSpA), designed for the shotgun reads, and Viral Assembler (VirA), which handles the amplicon reads. Both tools have been tested on simulated and real read data from HCV, HIV (ViSpA) and HBV (VirA) quasispecies, and shown to compare favourably with other existing methods.
C1 [Astrovskaya, Irina] Univ Maryland, Ctr Bioinformat & Computat, College Pk, MD 20742 USA.
[Mancuso, Nicholas; Tork, Bassam; Artyomenko, Alex] Georgia State Univ, Dept Comp Sci, Atlanta, GA 30303 USA.
[Mangul, Serghei; Zelikovsky, Alex] Univ Calif Los Angeles, Dept Comp Sci, Los Angeles, CA 90024 USA.
[Skums, Pavel; Ganova-Raeva, Lilia] Ctr Dis Control & Prevent, Div Viral Hepatitis, Atlanta, GA USA.
[Mandoiu, Ion] Univ Connecticut, Dept Comp Sci & Engn, Storrs, CT USA.
RP Astrovskaya, I (reprint author), Univ Maryland, Ctr Bioinformat & Computat, College Pk, MD 20742 USA.
EM iastrovskaya@gmail.com; nick.mancuso@gmail.com; basamt@gmail.com;
serghei@cs.ucla.edu; artyomenkoav@gmail.com; skumsp@gmail.com;
lkg7@cdc.gov; ion@engr.uconn.edu; alexz@cs.gsu.edu
OI Zelikovsky, Alexander/0000-0003-4424-4691
NR 68
TC 0
Z9 0
U1 0
U2 0
PU CAISTER ACADEMIC PRESS
PI WYMONDHAM
PA 32 HEWITTS LANE, WYMONDHAM NR 18 0JA, ENGLAND
BN 978-1-908230-68-3; 978-1-908230-29-4
PY 2014
BP 231
EP 262
PG 32
WC Biochemical Research Methods; Biochemistry & Molecular Biology; Genetics
& Heredity
SC Biochemistry & Molecular Biology; Genetics & Heredity
GA BF7MU
UT WOS:000384249900013
ER
PT J
AU Amek, NO
Odhiambo, FO
Khagayi, S
Moige, H
Orwa, G
Hamel, MJ
Van Eijk, A
Vulule, J
Slutsker, L
Laserson, KF
AF Amek, Nyaguara O.
Odhiambo, Frank O.
Khagayi, Sammy
Moige, Hellen
Orwa, Gordon
Hamel, Mary J.
Van Eijk, Annemieke
Vulule, John
Slutsker, Laurence
Laserson, Kayla F.
TI Childhood cause-specific mortality in rural Western Kenya: application
of the InterVA-4 model
SO GLOBAL HEALTH ACTION
LA English
DT Article
DE under-5; verbal autopsy; InterVA; health and demographic surveillance
AB Background: Assessing the progress in achieving the United Nation's Millennium Development Goals in terms of population health requires consistent and reliable information on cause-specific mortality, which is often rare in resource-constrained countries. Health and demographic surveillance systems (HDSS) have largely used medical personnel to review and assign likely causes of death based on the information gathered from standardized verbal autopsy (VA) forms. However, this approach is expensive and time consuming, and it may lead to biased results based on the knowledge and experience of individual clinicians. We assessed the cause-specific mortality for children under 5 years old (under-5 deaths) in Siaya County, obtained from a computer-based probabilistic model (InterVA-4).
Design: Successfully completed VA interviews for under-5 deaths conducted between January 2003 and December 2010 in the Kenya Medical Research Institute/US Centers for Disease Control and Prevention HDSS were extracted from the VA database and processed using the InterVA-4 (version 4.02) model for interpretation. Cause-specific mortality fractions were then generated from the causes of death produced by the model.
Results: A total of 84.33% (6,621) childhood deaths had completed VA data during the study period. Children aged 1-4 years constituted 48.53% of all cases, and 42.50% were from infants. A single cause of death was assigned to 89.18% (5,940) of cases, 8.35% (556) of cases were assigned two causes, and 2.10% (140) were assigned 'indeterminate' as cause of death by the InterVA-4 model. Overall, malaria (28.20%) was the leading cause of death, followed by acute respiratory infection including pneumonia (25.10%), in under-5 children over the study period. But in the first 5 years of the study period, acute respiratory infection including pneumonia was the main cause of death, followed by malaria. Similar trends were also reported in infants (29 days-11 months) and children aged 1-4 years.
Conclusions: Under-5 cause-specific mortality obtained using the InterVA-4 model is consistent with existing knowledge on the burden of childhood diseases in rural western Kenya.
C1 [Amek, Nyaguara O.; Odhiambo, Frank O.; Khagayi, Sammy; Moige, Hellen; Orwa, Gordon; Van Eijk, Annemieke; Vulule, John; Laserson, Kayla F.] Kenya Govt Med Res Ctr, Ctr Global Hlth Res, Kisumu, Kenya.
[Hamel, Mary J.; Slutsker, Laurence; Laserson, Kayla F.] Ctr Dis Control & Prevent, Ctr Global Hlth, Atlanta, GA USA.
RP Amek, NO (reprint author), Kenya Govt Med Res Ctr, POB 1578, Kisumu, Kenya.
EM namek@kemricdc.org
FU Sida (Research Cooperation); Wellcome Trust; William & Flora Hewlett
Foundation
FX We thank the study area community for providing this information, and
all HDSS staffs for assisting in collecting and processing it. KEMRI/CDC
HDSS is a member of the INDEPTH Network. This article is published with
permission from the Director of KEMRI. We are grateful to the INDEPTH
Secretariat for organising and funding a series of data analysis and
scientific writing workshops in Ghana, Thailand, Belgium and UK through
core support grants from Sida (Research Cooperation), the Wellcome Trust
and the William & Flora Hewlett Foundation.
NR 36
TC 5
Z9 5
U1 0
U2 0
PU CO-ACTION PUBLISHING
PI JARFALLA
PA RIPVAGEN 7, JARFALLA, SE-175 64, SWEDEN
SN 1654-9880
J9 GLOBAL HEALTH ACTION
JI Glob. Health Action
PY 2014
VL 7
AR 25581
DI 10.3402/gha.v7.25581
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA V44GA
UT WOS:000209736300001
PM 25377340
ER
PT J
AU Xu, XYS
Dong, RG
Welcome, DE
Warren, C
McDowell, TW
AF Xu, Xueyan S.
Dong, Ren G.
Welcome, Daniel E.
Warren, Christopher
McDowell, Thomas W.
TI An examination of the handheld adapter approach for measuring
hand-transmitted vibration exposure
SO MEASUREMENT
LA English
DT Article
DE Hand-arm vibration; Hand-transmitted vibration; Vibration measurement;
Vibration dosimeter; Handheld adapter
ID GLOVES; TOOLS; TRANSMISSIBILITY; WRIST; TIME; PALM
AB The use of a handheld adapter equipped with a tri-axial accelerometer is the most convenient and efficient approach for measuring vibration exposure at the hand-tool interface, especially when the adapter is incorporated into a miniature handheld or wrist-strapped dosimeter. To help optimize the adapter approach, the specific aims of this study are to identify and understand the major sources and mechanisms of measurement errors and uncertainties associated with using these adapters, and to explore their improvements. Five representative adapter models were selected and used in the experiment. Five human subjects served as operators in the experiment on a hand-arm vibration test system. The results of this study confirm that many of the handheld adapters can produce substantial overestimations of vibration exposure, and measurement errors can significantly vary with tool, adapter model, mounting position, mounting orientation, and subject. Major problems with this approach include unavoidable influence of the hand dynamic motion on the adapter, unstable attachment, insufficient attachment contact force, and inappropriate adapter structure. However, the results of this study also suggest that measurement errors can be substantially reduced if the design and use of an adapter can be systematically optimized toward minimizing the combined effects of the identified factors. Some potential methods for improving the design and use of the adapters are also proposed and discussed. Published by Elsevier Ltd.
C1 [Xu, Xueyan S.; Dong, Ren G.; Welcome, Daniel E.; Warren, Christopher; McDowell, Thomas W.] NIOSH, Engn & Control Technol Branch, Morgantown, WV 26505 USA.
RP Dong, RG (reprint author), NIOSH, ECTB, HELD, CDC, 1095 Willowdale Rd,MS L-2027, Morgantown, WV 26505 USA.
EM RDong@cdc.gov
OI McDowell, Thomas/0000-0002-2416-2210
FU Intramural CDC HHS [CC999999]
NR 39
TC 2
Z9 2
U1 1
U2 6
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0263-2241
EI 1873-412X
J9 MEASUREMENT
JI Measurement
PD JAN
PY 2014
VL 47
BP 64
EP 77
DI 10.1016/j.measurement.2013.08.037
PG 14
WC Engineering, Multidisciplinary; Instruments & Instrumentation
SC Engineering; Instruments & Instrumentation
GA 268UR
UT WOS:000328196600010
PM 26744580
ER
PT B
AU Zheng, ZC
Wei, Z
Bennett, JS
AF Zheng, Z. C.
Wei, Z.
Bennett, J. S.
GP ASME
TI INVESTIGATION OF EXHAUST CONDITIONS ON INFLUENCING CONTAMINANT TRANSPORT
FOR INDOOR ENVIRONMENTS
SO PROCEEDINGS OF THE ASME FLUIDS ENGINEERING DIVISION SUMMER MEETING -
2014, VOL 1A: SYMPOSIA
LA English
DT Proceedings Paper
CT 4th ASME Joint US-European Fluids Engineering Diviison Summer Meeting
CY AUG 03-07, 2014
CL Chicago, IL
SP ASME, Fluids Engn Div
ID PARTICLE DEPOSITION; CHAMBER; FLOWS; MODEL; ROOM
AB Indoor air quality is an important issue involved in a wide variety of industrial applications. In an indoor environment, different types of contaminants exist and have an inevitable potential to cause health problems for human beings and animals. In this study, the focus is on the contaminant contained in painting materials. While painting materials being sprayed to solid surfaces, pollutant plumes are formed near the painting area, which may enclose the body parts of the sprayers. Severe health problems are, possible to occur if a significant amount of painting materials settles on the face of workers. By applying exhaust conditions (i.e. exhaust fan with outlet velocity), the flow convection in the room can be enhanced, which may alleviate the contaminant level on the human body. In such a case, the choice of exhaust condition becomes crucial. With the aid of computational fluid dynamics, an optimal exhaust condition can be determined. To simulate this kind of fluid/solid-particle multiphase flow, the current study employs a pure Eulerian or Euler-Euler type model. In the Euler-Euler approach, the properties of the contaminant particles are assumed to be continuous as those of fluids and all phases are computed in the Eulerian framework. Since the exhaust speed is moderately low and fully turbulent flow is not guaranteed in the room, the RNG k-e model is used as a low Reynolds number turbulent model. The current paper firstly investigated the scenario of sprayer self-contamination. Then, inter-contaminations among different workers will be studied.
C1 [Zheng, Z. C.; Wei, Z.] Univ Kansas, Lawrence, KS 66045 USA.
[Bennett, J. S.] NIOSH, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA.
RP Zheng, ZC (reprint author), Univ Kansas, Lawrence, KS 66045 USA.
NR 9
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC MECHANICAL ENGINEERS
PI NEW YORK
PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA
BN 978-0-7918-4621-6
PY 2014
AR V01AT03A023
PG 8
WC Engineering, Mechanical
SC Engineering
GA BF0WK
UT WOS:000379634600038
ER
PT S
AU Cauda, E
Joy, G
Miller, A
Mischler, S
AF Cauda, Emanuele
Joy, Gerald
Miller, Arthur
Mischler, Steven
BE Harper, M
Lee, T
TI Analysis of the Silica Percent in Airborne Respirable Mine Dust Samples
From US Operations
SO SILICA AND ASSOCIATED RESPIRABLE MINERAL PARTICLES
SE American Society for Testing and Materials Special Technical
Publications
LA English
DT Proceedings Paper
CT Symposium on Silica and Associated Respirable Mineral Particles
CY OCT 25-26, 2012
CL Atlanta, GA
SP ASTM Int, Comm D22 Air Qual, ASTM Int, Subcommittee D22 04 Workplace Air Qual
DE mining; dust; silica content
ID COAL-DUST
AB Exposure to crystalline silica in mining can lead to silicosis, a potentially fatal lung disease, and it may be contributing to the increase of coal workers' pneumoconiosis (CWP) seen in Appalachian miners. Exposure to silica in mines is controlled indirectly by reducing the respirable dust exposure limit through a formula that employs the % of silica in the dust. To reduce this exposure, control technologies and specific monitoring techniques need to be developed and implemented and the knowledge of the % of silica in mine dusts can help this process. This manuscript analyzes the % of silica in dust samples for the U.S. mining industry collected from 1997 to 2011. In the metal/nonmetal (M/NM) industry, metal and sand and gravel mines showed the highest silica % (8.2 %, 9.8 %) along with the highest variability. The silica % was found to be lower for samples collected in underground by comparison to surface and mill. In the coal industry, the samples collected in surface locations showed high silica % in the dust. For both the coal and M/NM industries, the % of silica and the respirable dust concentration were inversely related-i.e., the lower the dust concentration, the higher and more variable silica percentages were observed. The respirable dust limit formula suggests the first explanation: a mine with a high silica % in the dust is required to keep the dust concentration low under the reduced standard. Additional explanations are also proposed: the variability of the % of silica in the dust, the selective efficiency of control technologies, and different transport properties for dust with variable silica content. The findings improve the understanding of exposure to silica in mining environments and the data presented will be helpful in developing monitoring strategies for the measurement of silica and for the design of control technologies.
C1 [Cauda, Emanuele; Joy, Gerald; Miller, Arthur; Mischler, Steven] Ctr Dis Control & Prevent, US Dept Hlth & Human Serv, Publ Hlth Serv, Natl Inst Occupat Safety & Hlth,Off Min Safety &, Pittsburgh, PA 15217 USA.
RP Cauda, E (reprint author), Ctr Dis Control & Prevent, US Dept Hlth & Human Serv, Publ Hlth Serv, Natl Inst Occupat Safety & Hlth,Off Min Safety &, Pittsburgh, PA 15217 USA.
NR 20
TC 0
Z9 0
U1 2
U2 2
PU ASTM INTERNATIONAL
PI WEST CONSHOHOCKEN
PA 100 BARR HARBOR DRIVE, PO BOX C700, WEST CONSHOHOCKEN, PA 19428-2959 USA
SN 0066-0558
BN 978-0-8031-7551-8
J9 AM SOC TEST MATER
PY 2014
VL 1565
BP 12
EP 27
DI 10.1520/STP156520120210
PG 16
WC Public, Environmental & Occupational Health; Materials Science,
Characterization & Testing
SC Public, Environmental & Occupational Health; Materials Science
GA BE4GE
UT WOS:000371678000002
ER
PT S
AU Stacey, P
Mecchia, M
Verpaele, S
Pretorius, C
Key-Schwartz, R
Mattenklott, M
Eypert-Blaison, C
Thorpe, A
Roberts, P
Frost, G
AF Stacey, Peter
Mecchia, Marco
Verpaele, Steven
Pretorius, Cecilia
Key-Schwartz, Rosa
Mattenklott, Markus
Eypert-Blaison, Celine
Thorpe, Andrew
Roberts, Paul
Frost, Gillian
BE Harper, M
Lee, T
TI Differences Between Samplers for Respirable Dust and the Analysis of
Quartz-An International Study
SO SILICA AND ASSOCIATED RESPIRABLE MINERAL PARTICLES
SE American Society for Testing and Materials Special Technical
Publications
LA English
DT Proceedings Paper
CT Symposium on Silica and Associated Respirable Mineral Particles
CY OCT 25-26, 2012
CL Atlanta, GA
SP ASTM Int, Comm D22 Air Qual, ASTM Int, Subcommittee D22 04 Workplace Air Qual
DE respirable; dust; sampler; quartz; XRD analysis; performance; Arizona
Road Dust; silica; X-ray diffraction; sampler uncertainty
ID FLOW RATE SAMPLERS; X-RAY-DIFFRACTION; ALPHA-QUARTZ; PERFORMANCE;
CYCLONE
AB Members of an international standards working group for silica measurement (ISO/TC146/SC2/WG7 Silica) collaborated to assess the differences between sample preparation approaches for the analysis of respirable crystalline silica (RCS) by X-ray diffraction (XRD). They also assessed the relative collection efficiencies of 13 respirable samplers. The evaluation involved nine laboratories from eight countries. Samplers were exposed to airborne concentrations of ultrafine and medium Arizona road dust (ARD) in a calm air chamber. Each participating laboratory analysed samples following their own method and the Health and Safety Laboratory (HSL) retained a third of the samples for verification. All methods and analytical approaches applied in this study obtained comparable results (most were within 12 %). An exception was a method used with the CIP10 R sampler, which reported lower values. Correcting for the crystallinity of the calibration quartz dust using a verified value tested against a certified reference material has one of the largest impacts on the comparability of results. When following good analytical practice, the main factors affecting the comparability of results for RCS are significant differences in sampler efficiencies. In particular, the conductive sampler from SKC obtained a higher concentration of respirable dust (1.3-1.4x) when compared with the average air concentration. The Dorr Oliver, SKC aluminium, CIP10 R, and IOM head (with polyurethane foam separator) samplers all reported lower respirable dust air concentrations than average with the ultrafine ARD. Their lower collection efficiency compared with other samplers is explainable from published sampler information. The Dorr Oliver sampler also had a tendency to collect a lower proportion of RCS in the respirable dust than others. The working group propose that more stringent particle size selection and mass collection criteria are used to improve consistency and crossutilisation of exposure data between countries.
C1 [Stacey, Peter; Thorpe, Andrew; Roberts, Paul; Frost, Gillian] HSL, Harpur Hill, Buxton SK17 9JN, England.
[Mecchia, Marco] INAIL, Italian Workers Compensat Author, Risk Assessment & Prevent Tech Advisory Off, I-00143 Rome, Italy.
[Verpaele, Steven] Adhesia, B-1000 Brussels, Belgium.
[Pretorius, Cecilia] CSIR Ctr Min Innovat, Human Factors Res Grp, Pretoria, South Africa.
[Key-Schwartz, Rosa] NIOSH, Cincinnati, OH 45226 USA.
[Mattenklott, Markus] IFA Inst Arbeitsschutz Deutsch Gesetzlichen Unfal, D-53757 St Augustin, Germany.
[Eypert-Blaison, Celine] INRS Inst Natl Rech & Secur, Ctr Lorraine, Dept Metrol Polluants, Lab Anal Inorgan & Caracterisat Aerosols, F-54519 Vandoeuvre Les Nancy, France.
RP Stacey, P (reprint author), HSL, Harpur Hill, Buxton SK17 9JN, England.
EM peter.stacey@hsl.gov.uk
NR 31
TC 0
Z9 0
U1 1
U2 1
PU ASTM INTERNATIONAL
PI WEST CONSHOHOCKEN
PA 100 BARR HARBOR DRIVE, PO BOX C700, WEST CONSHOHOCKEN, PA 19428-2959 USA
SN 0066-0558
BN 978-0-8031-7551-8
J9 AM SOC TEST MATER
PY 2014
VL 1565
BP 73
EP 102
DI 10.1520/STP156520120188
PG 30
WC Public, Environmental & Occupational Health; Materials Science,
Characterization & Testing
SC Public, Environmental & Occupational Health; Materials Science
GA BE4GE
UT WOS:000371678000006
ER
PT S
AU Coggins, MA
Healy, CB
Lee, T
Harper, M
AF Coggins, Marie A.
Healy, Catherine B.
Lee, Taekhee
Harper, Martin
BE Harper, M
Lee, T
TI Performance of High-Flow-Rate Samplers for Respirable Crystalline Silica
Measurement Under Field Conditions: Preliminary Study
SO SILICA AND ASSOCIATED RESPIRABLE MINERAL PARTICLES
SE American Society for Testing and Materials Special Technical
Publications
LA English
DT Proceedings Paper
CT Symposium on Silica and Associated Respirable Mineral Particles
CY OCT 25-26, 2012
CL Atlanta, GA
SP ASTM Int, Comm D22 Air Qual, ASTM Int, Subcommittee D22 04 Workplace Air Qual
DE Respirable crystalline silica; Occupational exposure assessment; Stone
masonry
ID DUST; QUARTZ; EXPOSURE
AB Restoration stone work regularly involves work with high-silica-content materials (e.g., sandstone), but low-silica-content materials (<2 % quartz) such as limestone and lime mortar are also used. A combination of short sample duration and low silica content makes the quantification of worker exposure to respirable crystalline silica (RCS) difficult. This problem will be further compounded by the introduction of lower occupational exposure standards for RCS. The objective of this work was to determine whether higher-flow samplers might be an effective tool in characterizing lower RCS concentrations. A short study was performed to evaluate the performance of three high-flow samplers (FSP10, CIP10-R, and GK2.69) using side-by-side sampling with low-flow samplers (SIMPEDS and 10-mm nylon cyclones) for RCS exposure measurement at a restoration stonemasonry field site. A total of 19 side-by-side sample replicates for each high-flow and low-flow sampler pair were collected from work tasks involving limestone and sandstone. RESULTS. Most of the RCS (quartz) masses collected with the high-flow-rate samplers were above the limit of detection (62 % to 84 %) relative to the low-flow-rate samplers (58 % to 78 %). The average of the respirable mass concentration ratios for CIP10-R/SIMPEDS, GK2.69/10-mm nylon, FSP10/SIMPEDS, and FSP10/10-mm nylon pairs and the range of the quartz concentration ratios for the CIP10-R/SIMPEDS, CIP10-R/10-mm nylon, GK2.69/10-mm nylon, FSP10/SIMPEDS, and FSP10/10-mm nylon pairs included unity with an average close to unity, indicating no likely difference between the reported values for each sampler. Workers reported problems related to the weight of the sampling pumps for the high-flow-rate samplers. Respirable mass concentration data suggest that the high-flow-rate samplers evaluated would be appropriate for sampling respirable dust concentrations during restoration stone work. Results from the comparison of average quartz concentration ratios between high- and low-flow samplers suggest that the higher mass collected by the high-flow-rate samplers did not interfere with the quartz measurement. A significant portion of the data collected with the high-flow-rate samplers (>82 %) were greater than the limit of detection, which indicates that these samplers are suitable for quantifying exposures, even with low-quartz materials.
C1 [Coggins, Marie A.; Healy, Catherine B.] Natl Univ Ireland, Sch Phys, Galway, Ireland.
[Lee, Taekhee; Harper, Martin] Ctr Dis Control & Prevent, Exposure Assessment Branch, HELD, NIOSH, Morgantown, WV 26505 USA.
RP Coggins, MA (reprint author), Natl Univ Ireland, Sch Phys, Galway, Ireland.
NR 23
TC 1
Z9 1
U1 0
U2 0
PU ASTM INTERNATIONAL
PI WEST CONSHOHOCKEN
PA 100 BARR HARBOR DRIVE, PO BOX C700, WEST CONSHOHOCKEN, PA 19428-2959 USA
SN 0066-0558
BN 978-0-8031-7551-8
J9 AM SOC TEST MATER
PY 2014
VL 1565
BP 125
EP 138
DI 10.1520/STP156520130141
PG 14
WC Public, Environmental & Occupational Health; Materials Science,
Characterization & Testing
SC Public, Environmental & Occupational Health; Materials Science
GA BE4GE
UT WOS:000371678000008
ER
PT S
AU Chisholm, WP
Lee, T
Chirila, M
AF Chisholm, William P.
Lee, Taekhee
Chirila, Madalina
BE Harper, M
Lee, T
TI Determination of Crystalline Silica in Dust at Low Concentrations by
Low-Temperature Infrared Spectrometry
SO SILICA AND ASSOCIATED RESPIRABLE MINERAL PARTICLES
SE American Society for Testing and Materials Special Technical
Publications
LA English
DT Proceedings Paper
CT Symposium on Silica and Associated Respirable Mineral Particles
CY OCT 25-26, 2012
CL Atlanta, GA
SP ASTM Int, Comm D22 Air Qual, ASTM Int, Subcommittee D22 04 Workplace Air Qual
DE respirable quartz dust; silica dust; FTIR
ID LUNG-CANCER; RESPIRABLE QUARTZ; RISK-ASSESSMENT; QUANTIFICATION;
SPECTROSCOPY; DIFFRACTION; RELAXATION; WORKERS
AB The American Conference of Governmental Industrial Hygienists (ACGIH) accepted a lower threshold limit value (TLV) for respirable crystalline silica (RCS) exposure of 25 mu g/m(3), half of the previous TLV. This change is problematic because the current standard sampling and measurement practices used by NIOSH, OSHA, and MSHA are not sensitive enough to allow an analyst to confidently determine samples acquired near the TLV. In response to this need for a more sensitive method to analyze respirable dust filter samples for crystalline silica, a modification of current NIOSH infrared spectrometric methods is being developed. The additional sensitivity is gained by performing the infrared absorbance measurements at 77K where absorbance peaks are more intense by virtue of being narrower. A quick-change cryostat has been fabricated such that a sample can be introduced to the spectrometer and cooled to 77K in 5 min, interrogated for 1min, and removed and the cryostat readied for another sample in 2 min, for a turnaround time of 8 min per sample, which is brief compared to the time required to prepare and redeposit a sample. Therefore, samples can be acquired and interrogated with legacy samplers, filters, pumps, spectrometers, and sample preparation, the only modification being the addition of a cryostat to the spectrometer. Preliminary experiments demonstrate that the peak-to-background ratio of the quartz signature band near 800 cm(-1) increases by approximately 50 % on cooling from room temperature to 77 K. The slopes of the calibration curve derived from standards interrogated at both room temperature and 77K indicate that the low-temperature method is approximately 25 % more sensitive.
C1 [Chisholm, William P.; Lee, Taekhee; Chirila, Madalina] Ctr Dis Control & Prevent, Exposure Assessment Branch, Hlth Effects Lab Div, NIOSH, Morgantown, WV 26505 USA.
RP Chisholm, WP (reprint author), Ctr Dis Control & Prevent, Exposure Assessment Branch, Hlth Effects Lab Div, NIOSH, Morgantown, WV 26505 USA.
NR 25
TC 0
Z9 0
U1 0
U2 0
PU ASTM INTERNATIONAL
PI WEST CONSHOHOCKEN
PA 100 BARR HARBOR DRIVE, PO BOX C700, WEST CONSHOHOCKEN, PA 19428-2959 USA
SN 0066-0558
BN 978-0-8031-7551-8
J9 AM SOC TEST MATER
PY 2014
VL 1565
BP 169
EP 179
DI 10.1520/STP156520130029
PG 11
WC Public, Environmental & Occupational Health; Materials Science,
Characterization & Testing
SC Public, Environmental & Occupational Health; Materials Science
GA BE4GE
UT WOS:000371678000010
ER
PT S
AU Yu, LL
Fassett, JD
MacDonald, BS
Butler, TA
Ramsey, DM
Key-Schwartz, RJ
Rains, TC
AF Yu, Lee L.
Fassett, John D.
MacDonald, Bruce S.
Butler, Therese A.
Ramsey, Dawn M.
Key-Schwartz, Rosa J.
Rains, Theodore C.
BE Harper, M
Lee, T
TI Development of SRMs 295x and 296x, Respirable Crystalline Silica on
Filter
SO SILICA AND ASSOCIATED RESPIRABLE MINERAL PARTICLES
SE American Society for Testing and Materials Special Technical
Publications
LA English
DT Proceedings Paper
CT Symposium on Silica and Associated Respirable Mineral Particles
CY OCT 25-26, 2012
CL Atlanta, GA
SP ASTM Int, Comm D22 Air Qual, ASTM Int, Subcommittee D22 04 Workplace Air Qual
DE respirable; alpha quartz; cristobalite; ICP-OES; Standard Reference
Material; SRM; uncertainty budget; combining results
AB Standard Reference Material (SRM VR) series 2951 to 2958 (5 mu g to 1000 mu g) Respirable Alpha Quartz on Filter and SRM series 2961 to 2967 (5 mu g to 1000 mu g) Respirable Cristobalite on Filter were prepared gravimetrically by depositing SRM 1878 a Respirable Alpha Quartz and SRM 1879 a Respirable Cristobalite on filters, respectively. These new SRMs are developed to assure the quality of respirable crystalline silica measurements using x-ray diffraction and infrared spectrometry around the regulatory limits that are enforced by the Occupational Safety and Health Administration (OSHA). The mass of silica determined by highly sensitive, but non-polymorph-specific, inductively coupled plasma optical emission spectrometry (ICP-OES) was successfully used to calculate the mass of polymorph-specific crystalline silica on filter after all sources of Si on the new SRMs were carefully analyzed. The certified values of alpha quartz in SRMs 2951 to 2958 and cristobalite in SRMs 2961 to 2967, respectively, were established from the gravimetric preparation values and the spectrometric measurement values.
C1 [Yu, Lee L.; Fassett, John D.; MacDonald, Bruce S.; Butler, Therese A.] NIST, Gaithersburg, MD 20899 USA.
[Ramsey, Dawn M.; Key-Schwartz, Rosa J.] NIOSH, Cincinnati, OH 45226 USA.
[Rains, Theodore C.] High Pur Stand, Charleston, SC USA.
RP Yu, LL (reprint author), NIST, Gaithersburg, MD 20899 USA.
NR 8
TC 1
Z9 1
U1 0
U2 0
PU ASTM INTERNATIONAL
PI WEST CONSHOHOCKEN
PA 100 BARR HARBOR DRIVE, PO BOX C700, WEST CONSHOHOCKEN, PA 19428-2959 USA
SN 0066-0558
BN 978-0-8031-7551-8
J9 AM SOC TEST MATER
PY 2014
VL 1565
BP 222
EP 231
DI 10.1520/STP156512239
PG 10
WC Public, Environmental & Occupational Health; Materials Science,
Characterization & Testing
SC Public, Environmental & Occupational Health; Materials Science
GA BE4GE
UT WOS:000371678000014
ER
PT S
AU Hayes, T
Parish, H
Key-Schwartz, R
Popp, D
AF Hayes, Terry
Parish, Helen
Key-Schwartz, Rosa
Popp, Derek
BE Harper, M
Lee, T
TI An Evaluation of Aerosol- and Liquid-Generated Silica Samples for
Proficiency Analytical Testing
SO SILICA AND ASSOCIATED RESPIRABLE MINERAL PARTICLES
SE American Society for Testing and Materials Special Technical
Publications
LA English
DT Proceedings Paper
CT Symposium on Silica and Associated Respirable Mineral Particles
CY OCT 25-26, 2012
CL Atlanta, GA
SP ASTM Int, Comm D22 Air Qual, ASTM Int, Subcommittee D22 04 Workplace Air Qual
DE proficiency analytical testing; Fourier transform infrared spectrometry
(FTIR); X-ray diffraction (XRD); silica; aerosol-generation;
liquid-generation
AB SRI International has prepared dynamically generated silica samples since 1980 for the National Institute of Occupational Safety and Health (NIOSH) and the American Industrial Hygiene Association (AIHA) Proficiency Analytical Testing (PAT) programs. Aerosol-generated samples were developed in 1980 to more closely approximate real world samples and to improve intrabatch precision. Liquid-generated samples may provide tighter control limits, and this method has been reexamined as the generation procedure of choice. Sample preparation procedures have also been investigated to minimize analytical uncertainty and, hence, obtain a true evaluation of the sampling error. Samples were analyzed by SRI, NIOSH, and the Wisconsin Occupational Health Laboratory, using X-ray diffraction or Fourier transform infrared spectrometry (FTIR). Results were plotted and statistically evaluated, then compared to the existing PAT interlaboratory database.
C1 [Hayes, Terry] SRI Int, Analyt Chem, 333 Ravenswood Ave, Menlo Pk, CA 94025 USA.
[Parish, Helen] SRI Int, Dept Analyt Chem, Menlo Pk, CA 94025 USA.
[Key-Schwartz, Rosa] NIOSH, Alice Hamilton Lab, Cincinnati, OH 45213 USA.
[Popp, Derek] Wisconsin State Lab Hyg, Wisconsin Occupat Hlth Lab, Madison, WI 53707 USA.
RP Hayes, T (reprint author), SRI Int, Analyt Chem, 333 Ravenswood Ave, Menlo Pk, CA 94025 USA.
EM terry.hayes@sri.com
NR 4
TC 0
Z9 0
U1 0
U2 0
PU ASTM INTERNATIONAL
PI WEST CONSHOHOCKEN
PA 100 BARR HARBOR DRIVE, PO BOX C700, WEST CONSHOHOCKEN, PA 19428-2959 USA
SN 0066-0558
BN 978-0-8031-7551-8
J9 AM SOC TEST MATER
PY 2014
VL 1565
BP 232
EP 240
DI 10.1520/STP156512243
PG 9
WC Public, Environmental & Occupational Health; Materials Science,
Characterization & Testing
SC Public, Environmental & Occupational Health; Materials Science
GA BE4GE
UT WOS:000371678000015
ER
PT J
AU Hudson, NL
Kasner, EJ
Beckman, J
Mehler, L
Schwartz, A
Higgins, S
Bonnar-Prado, J
Lackovic, M
Mulay, P
Mitchell, Y
Larios, L
Walker, R
Waltz, J
Moraga-McHaley, S
Roisman, R
Calvert, GM
AF Hudson, Naomi L.
Kasner, Edward J.
Beckman, John
Mehler, Louise
Schwartz, Abby
Higgins, Sheila
Bonnar-Prado, Joanne
Lackovic, Michelle
Mulay, Prakash
Mitchell, Yvette
Larios, Leo
Walker, Rob
Waltz, Justin
Moraga-McHaley, Stephanie
Roisman, Rachel
Calvert, Geoffrey M.
TI Characteristics and Magnitude of Acute Pesticide-Related Illnesses and
Injuries Associated With Pyrethrin and Pyrethroid Exposures-11 States,
2000-2008
SO AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
LA English
DT Article
DE pyrethrin; pyrethroid; surveillance; pesticide; illness
ID INSECTICIDES
AB Background Excluding disinfectants, pyrethrins and pyrethroids are the pesticides used most commonly in and around homes. Respiratory effects and paresthesia are among the concerns about pyrethrin/pyrethroid exposures.
MethodsAcute pesticide-related illness/injury cases were identified from the Sentinel Event Notification System for Occupational Risks-Pesticides Program and the California Department of Pesticide Regulation from 2000-2008. Characteristics and incidence rates were determined for acute pyrethrin/pyrethroid-related illness/injury cases. Logistic regression analyses were performed to determine odds of respiratory and dermal symptoms in persons with illness/injury following pyrethrin/pyrethroid exposure compared to persons with illness/injury following exposure to other pesticides.
ResultsA total of 4,974 cases of acute pyrethrin/pyrethroid-related illness were identified. Incidence rates increased over time, reaching 8 cases/million population in 2008. The majority of cases were low severity (85%) and 34% were work-related. Respiratory effects were the most common symptoms reported (48%). Risk of acute respiratory effects were significantly elevated among persons exposed only to pyrethrins (adjusted odds ratio [aOR] 1.79; 95% confidence interval [95% CI]: 1.49-2.16), only to pyrethroids (aOR 1.99 95% CI: 1.77-2.24), to a mixture of pyrethroids (aOR 2.36; 95% CI: 1.99-2.81) or to a mixture containing both pyrethrins and pyrethroids (aOR 2.99; 95% CI: 2.33-3.84) compared to those with illness arising from exposure to other pesticides. The most common factors contributing to pyrethrin/pyrethroid-related illness included exposure from spills/splashes, improper storage, and failure to evacuate during pesticide application.
ConclusionsThe magnitude of acute pyrethrin/pyrethroid-related illness/injury is relatively low but is increasing. As such, additional measures to prevent them are needed. Am. J. Ind. Med. 57:15-30, 2014. (c) 2013 Wiley Periodicals, Inc.
C1 [Hudson, Naomi L.; Kasner, Edward J.; Calvert, Geoffrey M.] NIOSH, Div Surveillance Hazard Evaluat & Field Studies, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA.
[Beckman, John; Roisman, Rachel] Calif Dept Publ Hlth, Richmond, CA USA.
[Beckman, John] Inst Publ Hlth, Oakland, CA USA.
[Mehler, Louise] Calif Dept Pesticide Regulat, Sacramento, CA USA.
[Schwartz, Abby] Michigan Dept Community Hlth, Div Environm Hlth, Lansing, MI USA.
[Higgins, Sheila] North Carolina Dept Hlth & Human Serv, Div Publ Hlth, Raleigh, NC USA.
[Bonnar-Prado, Joanne] Washington State Dept Hlth, Off Environm Hlth Safety & Toxicol, Olympia, WA USA.
[Lackovic, Michelle] Louisiana Dept Hlth & Hosp, New Orleans, LA USA.
[Mulay, Prakash] Florida Dept Hlth, Tallahassee, FL USA.
[Mitchell, Yvette] New York State Dept Hlth, Bur Occupat Hlth & Injury Prevent, Troy, NY USA.
[Larios, Leo] Texas Dept State Hlth Serv, Environm & Injury Epidemiol & Toxicol Unit, Austin, TX USA.
[Walker, Rob] Iowa Dept Publ Hlth, Des Moines, IA 50319 USA.
[Waltz, Justin] Oregon Hlth Author, Off Environm Publ Hlth, Portland, OR USA.
[Moraga-McHaley, Stephanie] New Mexico Dept Hlth, Albuquerque, NM USA.
RP Calvert, GM (reprint author), NIOSH, 4676 Columbia Pkwy,R-17, Cincinnati, OH 45226 USA.
EM jac6@cdc.gov
NR 38
TC 8
Z9 8
U1 3
U2 16
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0271-3586
EI 1097-0274
J9 AM J IND MED
JI Am. J. Ind. Med.
PD JAN
PY 2014
VL 57
IS 1
BP 15
EP 30
DI 10.1002/ajim.22216
PG 16
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 263DP
UT WOS:000327787100003
PM 23788228
ER
PT J
AU Bang, KM
Mazurek, JM
Wood, JM
Hendricks, SA
AF Bang, Ki Moon
Mazurek, Jacek M.
Wood, John M.
Hendricks, Scott A.
TI Diseases Attributable to Asbestos Exposure: Years of Potential Life
Lost, United States, 1999-2010
SO AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
LA English
DT Article
DE years of potential life lost; mortality; asbestos; asbestosis; malignant
mesothelioma; lung cancer
ID PREMATURE MORTALITY; CANCER; WORK; RISK; AGE
AB Background Although asbestos use has been restricted in recent decades, asbestos-associated deaths continue to occur in the United States.
ObjectivesWe evaluated premature mortality and loss of potentially productive years of life attributable to asbestos-associated diseases.
MethodsUsing 1999-2010 National Center for Health Statistics mortality data, we identified decedents aged 25 years whose death certificate listed asbestosis and malignant mesothelioma as the underlying cause of death. We computed years of potential life lost to life expectancy (YPLL) and to age 65 (YPLL65).
ResultsDuring 1999-2010, a total of 427,005 YPLL and 55,184 YPLL65 were attributed to asbestosis (56,907 YPLL and 2,167 YPLL65), malignant mesothelioma (370,098 YPPL and 53,017 YPLL65). Overall and disease-specific asbestos-attributable total YPLL and YPLL65 and median YPLL and YPLL65 per decedent did not change significantly from 1999 to 2010.
ConclusionsThe continuing occurrence of asbestos-associated diseases and their substantial premature mortality burden underscore the need for maintaining prevention efforts and for ongoing surveillance to monitor temporal trends in these diseases. Am. J. Ind. Med. 57:38-48, 2014. (c) 2013 Wiley Periodicals, Inc.
C1 [Bang, Ki Moon; Mazurek, Jacek M.; Wood, John M.; Hendricks, Scott A.] NIOSH, Ctr Dis Control & Prevent, Morgantown, WV 26505 USA.
RP Bang, KM (reprint author), NIOSH, Div Resp Dis Studies, Ctr Dis Control & Prevent, Mailstop H-G900-2 1095 Willowdale Rd, Morgantown, WV 26505 USA.
EM kmb2@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 40
TC 3
Z9 3
U1 0
U2 9
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0271-3586
EI 1097-0274
J9 AM J IND MED
JI Am. J. Ind. Med.
PD JAN
PY 2014
VL 57
IS 1
BP 38
EP 48
DI 10.1002/ajim.22261
PG 11
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 263DP
UT WOS:000327787100005
PM 24108494
ER
PT J
AU Luckhaupt, SE
Sussell, AL
Sweeney, MH
Sestito, JP
Calvert, GM
AF Luckhaupt, Sara E.
Sussell, Aaron L.
Sweeney, Marie H.
Sestito, John P.
Calvert, Geoffrey M.
TI Prevalence of Work-Related Dermatitis in the Working Population:
Authors' Response to Letter from Rosenman and Fussman
SO AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
LA English
DT Letter
ID ASTHMA; SURVEILLANCE; MICHIGAN
C1 [Luckhaupt, Sara E.; Sussell, Aaron L.; Sweeney, Marie H.; Sestito, John P.; Calvert, Geoffrey M.] NIOSH, Div Surveillance Hazard Evaluat & Field Studies, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA.
RP Luckhaupt, SE (reprint author), NIOSH, 4676 Columbia Pkwy,R-17, Cincinnati, OH 45226 USA.
EM sluckhaupt@cdc.gov
NR 8
TC 1
Z9 1
U1 0
U2 1
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0271-3586
EI 1097-0274
J9 AM J IND MED
JI Am. J. Ind. Med.
PD JAN
PY 2014
VL 57
IS 1
BP 127
EP 128
DI 10.1002/ajim.22276
PG 2
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 263DP
UT WOS:000327787100015
PM 24307069
ER
PT J
AU Rasmussen, SA
Jamieson, DJ
AF Rasmussen, Sonja A.
Jamieson, Denise J.
TI Maternal mortality due to pandemic influenza A H1N1 2009 virus in
Colombia
SO JOURNAL OF PERINATAL MEDICINE
LA English
DT Editorial Material
ID PREGNANT-WOMEN; UNITED-STATES; ILLNESS
C1 [Rasmussen, Sonja A.] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
[Rasmussen, Sonja A.] Ctr Dis Control & Prevent, Influenza Coordinat Unit, Off Infect Dis, Atlanta, GA 30333 USA.
[Jamieson, Denise J.] Ctr Dis Control & Prevent, Womens Hlth & Fertil Branch, Div Reprod Hlth, Atlanta, GA 30333 USA.
RP Rasmussen, SA (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd,MS A-28, Atlanta, GA 30333 USA.
EM skr9@cdc.gov
OI Rasmussen, Sonja/0000-0002-0574-4928
NR 15
TC 0
Z9 0
U1 0
U2 3
PU WALTER DE GRUYTER GMBH
PI BERLIN
PA GENTHINER STRASSE 13, D-10785 BERLIN, GERMANY
SN 0300-5577
EI 1619-3997
J9 J PERINAT MED
JI J. Perinat. Med.
PD JAN
PY 2014
VL 42
IS 1
BP 27
EP 29
DI 10.1515/jpm-2013-0228
PG 3
WC Obstetrics & Gynecology; Pediatrics
SC Obstetrics & Gynecology; Pediatrics
GA 262VE
UT WOS:000327765200004
PM 24142342
ER
PT J
AU Sinks, T
AF Sinks, Thomas
TI Screenings and clusters: a cancer cluster in a chemical plant
SO OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
LA English
DT Editorial Material
C1 Natl Ctr Environm Hlth, Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
RP Sinks, T (reprint author), Natl Ctr Environm Hlth, Ctr Dis Control & Prevent, Mailstop F61,1600 Clifton Rd, Atlanta, GA 30333 USA.
EM ths2@cdc.gov
NR 8
TC 0
Z9 0
U1 0
U2 0
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 1351-0711
EI 1470-7926
J9 OCCUP ENVIRON MED
JI Occup. Environ. Med.
PD JAN
PY 2014
VL 71
IS 1
BP 2
EP 3
DI 10.1136/oemed-2013-101789
PG 2
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 263UZ
UT WOS:000327834800002
PM 24265265
ER
PT B
AU Igietseme, JU
Zhu, XP
Black, CM
AF Igietseme, Joseph U.
Zhu, Xiaoping
Black, Carolyn M.
BA Ackerman, ME
Nimmerjahn, F
BF Ackerman, ME
Nimmerjahn, F
TI Fc Receptor-Dependent Immunity
SO ANTIBODY FC: LINKING ADAPTIVE AND INNATE IMMUNITY
LA English
DT Article; Book Chapter
ID CYTOTOXIC T-LYMPHOCYTES; DENDRITIC CELLS; INTRACELLULAR PATHOGENS;
CHLAMYDIA-TRACHOMATIS; MEDIATED PHAGOCYTOSIS; PROTECTIVE IMMUNITY; GAMMA
RECEPTORS; INFECTION; ANTIBODIES; MOLECULES
C1 [Igietseme, Joseph U.; Black, Carolyn M.] Ctr Dis Control & Prevent, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA.
[Igietseme, Joseph U.] Morehouse Sch Med, Dept Microbiol & Immunol, Atlanta, GA 30310 USA.
[Zhu, Xiaoping] Univ Maryland, College Pk, MD 20742 USA.
RP Igietseme, JU (reprint author), Ctr Dis Control & Prevent, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA.
NR 53
TC 0
Z9 0
U1 0
U2 1
PU ELSEVIER ACADEMIC PRESS INC
PI SAN DIEGO
PA 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 USA
BN 978-0-12-394818-2; 978-0-12-394802-1
PY 2014
BP 269
EP 281
PG 13
WC Immunology
SC Immunology
GA BHU43
UT WOS:000326685100015
ER
PT J
AU Olsen, EO
Eaton, DK
Park, S
Brener, ND
Blanck, HM
AF Olsen, Emily O'Malley
Eaton, Danice K.
Park, Sohyun
Brener, Nancy D.
Blanck, Heidi M.
TI Comparing Methods for Assessing Beverage Intake among High School
Students
SO AMERICAN JOURNAL OF HEALTH BEHAVIOR
LA English
DT Article
DE beverage intake; dietary assessment; adolescents; food frequency
questionnaire; Youth Risk Behavior Survey
ID FOOD-FREQUENCY QUESTIONNAIRE; RISK BEHAVIOR SURVEILLANCE; UNITED-STATES;
RELATIVE VALIDITY; CHILDREN; ADOLESCENTS; REPRODUCIBILITY; RELIABILITY;
CONSUMPTION; PREVALENCE
AB Objectives: To compare 7 beverage intake survey questions against criterion data from 24-hour dietary recall interviews (24HrDRIs) among adolescents. Methods: Data were available from 610 US high school students completing a survey and >= 3 24HrDRIs. Analyses compared mean intake (times/day) calculated from the survey to intake (servings/day) from the 24HrDRIs. Proportions of students reporting intake of >= 1 times/day were compared to the 24HrDRI results. Results: Survey data significantly correlated with 24HrDRI data (all corrected r: 0.26-0.49). Survey results differed from 24HrDRI results on reported intake of 5 beverages. Conclusion: Intake from these beverage questions should be reported in times/day, which is related to, but not a proxy for, servings/day. These questions are useful for population-level surveillance of beverage
C1 [Olsen, Emily O'Malley; Eaton, Danice K.; Brener, Nancy D.] Ctr Dis Control & Prevent, Div Adolescent & Sch Hlth, Atlanta, GA USA.
[Park, Sohyun; Blanck, Heidi M.] Ctr Dis Control & Prevent, Div Nutr Phys Act & Obes, Atlanta, GA USA.
RP Olsen, EO (reprint author), Ctr Dis Control & Prevent, Div Adolescent & Sch Hlth, Atlanta, GA USA.
EM eolsen@cdc.gov
NR 27
TC 2
Z9 2
U1 0
U2 20
PU PNG PUBLICATIONS
PI OAK RIDGE
PA 2205-K OAK RIDGE RD, #115, OAK RIDGE, NC 27310 USA
SN 1945-7359
J9 AM J HEALTH BEHAV
JI Am. J. Health Behav.
PY 2014
VL 38
IS 1
BP 114
EP 123
DI 10.5993/AJHB.38.1.12
PG 10
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 219VD
UT WOS:000324538100012
ER
PT J
AU Hall, HI
Tang, T
Westfall, AO
Mugavero, MJ
AF Hall, H. Irene
Tang, Tian
Westfall, Andrew O.
Mugavero, Michael J.
TI HIV Care Visits and Time to Viral Suppression, 19 US Jurisdictions, and
Implications for Treatment, Prevention and the National HIV/AIDS
Strategy
SO PLOS ONE
LA English
DT Article
ID INFECTED PERSONS; ANTIRETROVIRAL TREATMENT; EARLY RETENTION;
UNITED-STATES; MEDICAL-CARE; RECOMMENDATIONS; SOCIETY; PANEL;
ASSOCIATION; ENGAGEMENT
AB Objective: Early and regular care and treatment for human immunodeficiency virus (HIV) infection are associated with viral suppression, reductions in transmission risk and improved health outcomes for persons with HIV. We determined, on a population level, the association of care visits with time from HIV diagnosis to viral suppression.
Methods: Using data from 19 areas reporting HIV-related tests to national HIV surveillance, we determined time from diagnosis to viral suppression among 17,028 persons diagnosed with HIV during 2009, followed through December 2011, using data reported through December 2012. Using Cox proportional hazards models, we assessed factors associated with viral suppression, including linkage to care within 3 months of diagnosis, a goal set forth by the National HIV/AIDS Strategy, and number of HIV care visits as determined by CD4 and viral load test results, while controlling for demographic, clinical, and risk characteristics.
Results: Of 17,028 persons diagnosed with HIV during 2009 in the 19 areas, 76.6% were linked to care within 3 months of diagnosis and 57.0% had a suppressed viral load during the observation period. Median time from diagnosis to viral suppression was 19 months overall, and 8 months among persons with an initial CD4 count <= 350 cells/mu L. During the first 12 months after diagnosis, persons linked to care within 3 months experienced shorter times to viral suppression (higher rate of viral suppression per unit time, hazard ratio [HR] = 4.84 versus not linked within 3 months; 95% confidence interval [CI] 4.27, 5.48). Persons with a higher number of time- updated care visits also experienced a shorter time to viral suppression (HR = 1.51 per additional visit, 95% CI 1.49, 1.52).
Conclusions: Timely linkage to care and greater frequency of care visits were associated with faster time to viral suppression with implications for individual health outcomes and for secondary prevention.
C1 [Hall, H. Irene] Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA 30329 USA.
[Tang, Tian] ICF Int, Atlanta, GA USA.
[Westfall, Andrew O.; Mugavero, Michael J.] Univ Alabama Birmingham, Ctr AIDS Res, Birmingham, AL USA.
[Mugavero, Michael J.] Univ Alabama Birmingham, Dept Med, Div Infect Dis, Birmingham, AL 35294 USA.
RP Hall, HI (reprint author), Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA 30329 USA.
EM ixh1@cdc.gov
OI Westfall, Andrew/0000-0002-0468-4695
FU Centers for Disease Control and Prevention (CDC)
FX The Centers for Disease Control and Prevention (CDC) provides funding to
state and local health departments to conduct surveillance of HIV
disease in accordance with their own disease reporting regulations. CDC
provides technical guidance for the collection of data by the state and
local health departments and data are sent to CDC for national-level
analyses. Role of the Sponsors: The CDC reviewed and approved final
submission but the findings and conclusions in this report are those of
the authors and do not necessarily represent the views of the CDC.
NR 32
TC 17
Z9 17
U1 1
U2 10
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 31
PY 2013
VL 8
IS 12
AR e84318
DI 10.1371/journal.pone.0084318
PG 7
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 284MV
UT WOS:000329323900080
PM 24391937
ER
PT J
AU Talley, LE
Boyd, E
AF Talley, Leisel E.
Boyd, Erin
TI Challenges to the Programmatic Implementation of Ready to Use Infant
Formula in the Post-Earthquake Response, Haiti, 2010: A Program Review
SO PLOS ONE
LA English
DT Review
AB Background and Objectives: Following the 2010 earthquake in Haiti, infant and young child feeding was identified as a priority nutrition intervention. A new approach to support breastfeeding mothers and distribute ready-to-use infant formula (RUIF) to infants unable to breastfeed was established. The objective of the evaluation was to assess the implementation of infant feeding programs using RUIF in displaced persons camps in Port-au-Prince, Haiti during the humanitarian response.
Methods: A retrospective record review was conducted from April-July, 2010 to obtain data on infants receiving RUIF in 30 baby tents. A standardized data collection form was created based on data collected across baby tents and included: basic demographics, admission criteria, primary caretaker, feeding practices, and admission and follow-up anthropometrics.
Main Findings: Orphans and abandoned infants were the most frequent enrollees (41%) in the program. While the program targeted these groups, it is unlikely that this is a true reflection of population demographics. Despite programmatic guidance, admission criteria were not consistently applied across programs. Thirty-four percent of infants were undernourished (weight for age Z score <-2) at the time of admission. Defaulting accounted for 50% of all program exits and there was no follow-up of these children. Low data quality was a significant barrier.
Conclusions: The design, implementation and magnitude of the 'baby tents' using RUIF was novel in response to infant and young child feeding (IYCF) in emergencies and presented multiple challenges that should not be overlooked, including adherence to protocols and the adaption of emergency programs to existing programs. The implementation of IYCF programs should be closely monitored to ensure that they achieve the objectives set by the humanitarian community and national government. IYCF is an often overlooked component of emergency preparedness; however to improve response, generic protocols and pre-emergency training and preparedness should be established for humanitarian agencies.
C1 [Talley, Leisel E.] Ctr Dis Control & Prevent, Emergency Response & Recovery Branch, Atlanta, GA 30329 USA.
[Boyd, Erin] United Nations Childrens Fund, Nutr Sect, Program Div, New York, NY USA.
RP Talley, LE (reprint author), Ctr Dis Control & Prevent, Emergency Response & Recovery Branch, Atlanta, GA 30329 USA.
EM Ltalley@cdc.gov
NR 12
TC 2
Z9 2
U1 1
U2 12
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 31
PY 2013
VL 8
IS 12
AR e84043
DI 10.1371/journal.pone.0084043
PG 6
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 284MV
UT WOS:000329323900020
PM 24391877
ER
PT J
AU Verani, JR
McCracken, J
Arvelo, W
Estevez, A
Lopez, MR
Reyes, L
Moir, JC
Bernart, C
Moscoso, F
Gray, J
Olsen, SJ
Lindblade, KA
AF Verani, Jennifer R.
McCracken, John
Arvelo, Wences
Estevez, Alejandra
Renee Lopez, Maria
Reyes, Lissette
Carlos Moir, Juan
Bernart, Chris
Moscoso, Fabiola
Gray, Jennifer
Olsen, Sonja J.
Lindblade, Kim A.
TI Surveillance for Hospitalized Acute Respiratory Infection in Guatemala
SO PLOS ONE
LA English
DT Article
ID COMMUNITY-ACQUIRED PNEUMONIA; SYNCYTIAL VIRUS-INFECTIONS; CLINICAL
CHARACTERISTICS; YOUNG-CHILDREN; EPIDEMIOLOGY; DIAGNOSIS; ETIOLOGY;
RADIOGRAPHS; POPULATION; AMERICA
AB Acute respiratory infections (ARI) are an important cause of illness and death worldwide, yet data on the etiology of ARI and the population-level burden in developing countries are limited. Surveillance for ARI was conducted at two hospitals in Guatemala. Patients admitted with at least one sign of acute infection and one sign or symptom of respiratory illness met the criteria for a case of hospitalized ARI. Nasopharyngeal/oropharyngeal swabs were collected and tested by polymerase chain reaction for adenovirus, parainfluenza virus types 1,2 and 3, respiratory syncytial virus, influenza A and B viruses, human metapneumovirus, Chlamydia pneumioniae, and Mycoplasma pneumoniae. Urine specimens were tested for Streptococcus pneumoniae antigen. Blood culture and chest radiograph were done at the discretion of the treating physician. Between November 2007 and December 2011, 3,964 case-patients were enrolled. While cases occurred among all age groups, 2,396 (60.4%) cases occurred in children <5 years old and 463 (11.7%) among adults >= 65 years old. Viruses were found in 52.6% of all case-patients and 71.8% of those aged <1 year old; the most frequently detected was respiratory syncytial virus, affecting 26.4% of case-patients. Urine antigen testing for Streptococcus pneumoniae performed for case-patients >= 15 years old was positive in 15.1% of those tested. Among 2,364 (59.6%) of case-patients with a radiograph, 907 (40.0%) had findings suggestive of bacterial pneumonia. Overall, 230 (5.9%) case-patients died during the hospitalization. Using population denominators, the observed hospitalized ARI incidence was 128 cases per 100,000, with the highest rates seen among children <1 year old (1,703 per 100,000), followed by adults >= 65 years old (292 per 100,000). These data, which demonstrate a substantial burden of hospitalized ARI in Guatemala due to a variety of pathogens, can help guide public health policies aimed at reducing the burden of illness and death due to respiratory infections.
C1 [Verani, Jennifer R.] Ctr Dis Control & Prevent, Resp Dis Branch, Atlanta, GA 30333 USA.
[McCracken, John; Estevez, Alejandra; Renee Lopez, Maria; Bernart, Chris; Moscoso, Fabiola; Gray, Jennifer] Univ Valle Guatemala, Ctr Estudios Salud, Guatemala City, Guatemala.
[Arvelo, Wences; Lindblade, Kim A.] Ctr Dis Control & Prevent, Reg Off Cent Amer & Panama, Int Emerging Infect Program, Guatemala City, Guatemala.
[Arvelo, Wences; Lindblade, Kim A.] Ctr Dis Control & Prevent, Div Global Dis Detect & Emergency Response, Atlanta, GA USA.
[Reyes, Lissette] Minist Salud Publ & Asistencia Social, Field Epidemiol Training Program, Guatemala City, Guatemala.
[Reyes, Lissette] Minist Salud Publ & Asistencia Social, Area Salud Santa Rosa, Cuilapa, Guatemala.
[Carlos Moir, Juan] Minist Salud Publ & Asistencia Social, Area Salud Quetzaltenango, Quetzaltenango, Guatemala.
[Olsen, Sonja J.] Ctr Dis Control & Prevent, Influenza Div, Atlanta, GA USA.
RP Verani, JR (reprint author), Ctr Dis Control & Prevent, Resp Dis Branch, Atlanta, GA 30333 USA.
EM qzr7@cdc.gov
FU United States Centers for Disease Control and Prevention (CDC) [UO1
GH000028-02]
FX This publication was supported by Cooperative Agreement Number UO1
GH000028-02 from the United States Centers for Disease Control and
Prevention (CDC). The CDC participated in all aspects of study design,
data collection, data analysis and manuscript preparation.
NR 50
TC 12
Z9 12
U1 0
U2 4
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 31
PY 2013
VL 8
IS 12
AR e83600
DI 10.1371/journal.pone.0083600
PG 11
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 284NF
UT WOS:000329325200089
PM 24391792
ER
PT J
AU Bosch, FX
Broker, TR
Forman, D
Moscicki, AB
Gillison, ML
Doorbar, J
Stern, PL
Stanley, M
Arbyn, M
Poljak, M
Cuzick, J
Castle, PE
Schiller, JT
Markowitz, LE
Fisher, WA
Canfell, K
Denny, LA
Franco, EL
Steben, M
Kane, MA
Schiffman, M
Meijer, CJLM
Sankaranarayanan, R
Castellsague, X
Kim, JJ
Brotons, M
Alemany, L
Albero, G
Diaz, M
de Sanjose, S
AF Xavier Bosch, F.
Broker, Thomas R.
Forman, David
Moscicki, Anna-Barbara
Gillison, Maura L.
Doorbar, John
Stern, Peter L.
Stanley, Margaret
Arbyn, Marc
Poljak, Mario
Cuzick, Jack
Castle, Philip E.
Schiller, John T.
Markowitz, Lauri E.
Fisher, William A.
Canfell, Karen
Denny, Lynette A.
Franco, Eduardo L.
Steben, Marc
Kane, Mark A.
Schiffman, Mark
Meijer, Chris J. L. M.
Sankaranarayanan, Rengaswamy
Castellsague, Xavier
Kim, Jane J.
Brotons, Maria
Alemany, Laia
Albero, Ginesa
Diaz, Mireia
de Sanjose, Silvia
CA ICO Monograph 'Comprehensive Conto
TI Comprehensive Control of Human Papillomavirus Infections and Related
Diseases
SO VACCINE
LA English
DT Review
DE HPV; Cervical cancer; Anal cancer; Penile cancer; Vaginal cancer
ID CERVICAL-CANCER; PREVENTION; COUNTRIES; VACCINES; WORLD
AB Infection with human papillomavirus (HPV) is recognized as one of the major causes of infection-related cancer worldwide, as well as the causal factor in other diseases. Strong evidence for a causal etiology with HPV has been stated by the International Agency for Research on Cancer for cancers of the cervix uteri, penis, vulva, vagina, anus and oropharynx (including base of the tongue and tonsils). Of the estimated 12.7 million new cancers occurring in 2008 worldwide, 4.8% were attributable to HPV infection, with substantially higher incidence and mortality rates seen in developing versus developed countries. In recent years, we have gained tremendous knowledge about HPVs and their interactions with host cells, tissues and the immune system; have validated and implemented strategies for safe and efficacious prophylactic vaccination against HPV infections; have developed increasingly sensitive and specific molecular diagnostic tools for HPV detection for use in cervical cancer screening; and have substantially increased global awareness of HPV and its many associated diseases in women, men, and children. While these achievements exemplify the success of biomedical research in generating important public health interventions, they also generate new and daunting challenges: costs of HPV prevention and medical care, the implementation of what is technically possible, socio-political resistance to prevention opportunities, and the very wide ranges of national economic capabilities and health care systems. Gains and challenges faced in the quest for comprehensive control of HPV infection and HPV-related cancers and other disease are summarized in this review. The information presented may be viewed in terms of a reframed paradigm of prevention of cervical cancer and other HPV-related diseases that will include strategic combinations of at least four major components: 1) routine introduction of HPV vaccines to women in all countries, 2) extension and simplification of existing screening programs using HPV-based technology, 3) extension of adapted screening programs to developing populations, and 4) consideration of the broader spectrum of cancers and other diseases preventable by HPV vaccination in women, as well as in men. Despite the huge advances already achieved, there must be ongoing efforts including international advocacy to achieve widespread optimally universal implementation of HPV prevention strategies in both developed and developing countries.
This article summarizes information from the chapters presented in a special ICO Monograph 'Comprehensive Control of HPV Infections and Related Diseases' Vaccine Volume 30, Supplement 5, 2012. Additional details on each subtopic and full information regarding the supporting literature references may be found in the original chapters. (C) 2013 Elsevier Ltd. All rights reserved.
C1 [Xavier Bosch, F.; Castellsague, Xavier; Brotons, Maria; Alemany, Laia; Albero, Ginesa; Diaz, Mireia; de Sanjose, Silvia] IDIBELL, Catalan Inst Oncol, Canc Epidemiol Res Program, Lhospitalet De Llobregat, Barcelona, Spain.
[Broker, Thomas R.] Univ Alabama Birmingham, Birmingham, AL USA.
[Forman, David] Int Agcy Res Canc, Sect Canc Informat, F-69372 Lyon, France.
[Moscicki, Anna-Barbara] Univ Calif San Francisco, Dept Pediat, Div Adolescent Med, San Francisco, CA USA.
[Gillison, Maura L.] Ohio State Univ, Ctr Comprehens Canc, Columbus, OH 43210 USA.
[Doorbar, John] Natl Inst Med Res, Div Virol, London NW7 1AA, England.
[Stern, Peter L.] Univ Manchester, Paterson Inst Canc Res, Manchester, Lancs, England.
[Stanley, Margaret] Univ Cambridge, Dept Pathol, Cambridge CB2 1QP, England.
[Arbyn, Marc] Sci Inst Publ Hlth, Canc Epidemiol Unit, Brussels, Belgium.
[Arbyn, Marc] Univ Antwerp, Lab Cell Biol & Histol, B-2020 Antwerp, Belgium.
[Poljak, Mario] Univ Ljubljana, Fac Med, Inst Microbiol & Immunol, Ljubljana, Slovenia.
[Cuzick, Jack] Queen Mary Univ London, Wolfson Inst Prevent Med, London, England.
[Castle, Philip E.] Global Canc Initiat, Chestertown, MD USA.
[Schiller, John T.] NCI, Ctr Canc Res, Bethesda, MD 20892 USA.
[Markowitz, Lauri E.] Ctr Dis Control & Prevent, Natl Ctr HIV Viral Hepatitis STD & TB Prevent, Atlanta, GA USA.
[Fisher, William A.] Univ Western Ontario, Dept Psychol, Social Sci Ctr 7428, London, ON, Canada.
[Fisher, William A.] Univ Western Ontario, Dept Obstet & Gynaecol, Social Sci Ctr 7428, London, ON, Canada.
[Canfell, Karen] Univ NSW, Prince Wales Clin Sch, Lowy Canc Res Ctr, Newcastle, NSW, Australia.
[Canfell, Karen] NSW Canc Council, Canc Epidemiol Res Unit, Sydney, NSW, Australia.
[Denny, Lynette A.] Univ Cape Town, Groote Schuur Hosp, Dept Obstet & Gynaecol, ZA-7925 Cape Town, South Africa.
[Denny, Lynette A.] Univ Cape Town, Groote Schuur Hosp, Inst Infect Dis & Mol Med, ZA-7925 Cape Town, South Africa.
[Franco, Eduardo L.] McGill Univ, Div Canc Epidemiol, Montreal, PQ, Canada.
[Steben, Marc] Inst Natl Sante Publ Quebec, Montreal, PQ, Canada.
[Kane, Mark A.] Consultant Immunizat Policy, Mercer Isl, WA USA.
[Schiffman, Mark] NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
[Meijer, Chris J. L. M.] Vrije Univ Amsterdam Med Ctr, Dept Pathol, Amsterdam, Netherlands.
[Sankaranarayanan, Rengaswamy] Int Agcy Res Canc, Screening Grp, F-69372 Lyon, France.
[Castellsague, Xavier; Alemany, Laia; Albero, Ginesa; de Sanjose, Silvia] CIBER Epidemiol & Salud Publ CIBERESP, Madrid, Spain.
[Kim, Jane J.] Harvard Univ, Sch Publ Hlth, Dept Hlth Policy & Management, Ctr Hlth Decis Sci, Boston, MA 02115 USA.
RP Bosch, FX (reprint author), IDIBELL, Catalan Inst Oncol, Canc Epidemiol Res Program, Lhospitalet De Llobregat, Barcelona, Spain.
EM admincerp@iconcologia.net
RI de Sanjose Llongueras, Silvia/H-6339-2014; Bruni, Laia/N-5816-2014;
BOSCH JOSE, FRANCESC XAVIER/J-6339-2012; Castellsague Pique,
Xavier/N-5795-2014; DIAZ SANCHIS, MIREIA/H-6335-2014; Albero,
Ginesa/G-7248-2015;
OI Bruni, Laia/0000-0003-3943-0326; BOSCH JOSE, FRANCESC
XAVIER/0000-0002-7172-3412; Castellsague Pique,
Xavier/0000-0002-0802-3595; Albero, Ginesa/0000-0002-9400-1914; Kjaer,
Susanne/0000-0002-8347-1398; Franco, Eduardo/0000-0002-4409-8084
FU European Commission [HEALTH-F3-2010-242061, HEALTH-F2-2011-282562,
242061]; Instituto de Salud Carlos III (Spanish Government) [FIS
PI08/1535, FIS PI10/02995, FIS PI11/02090, FIS PI11/02096, FIS
PI11/02104, RCESP C03/09, RTICESP C03/10, RTIC RD06/0020/0095,
RD12/0036/0056, CIBERESP]; Agencia de Gestio d'Ajuts Universitaris i de
Recerca Generalitat de Catalunya (Catalonian Government) [AGAUR
2005SGR00695, AGAUR 2009SGR126]; USPHS/NIH/National Cancer Institute
[CA36200, CA83679]; US Public Health Service (National Cancer Institute,
National Institutes of Health, Department of Health and Human Services)
[R37 CA51323]; National Institute of AIDS and Infectious Disease [RC1
AI86051]; UK Medical Research Council [MC_U117584278]; Belgian
Foundation Against Cancer (Brussels, Belgium); International Agency for
Research on Cancer (Lyon, France); Cancer Research UK [A10404]; National
Health and Medical Research Council, Australia [CDF APP1007994,
1007518]; Bill and Melinda Gates Foundation, USA [35537]; U.S. National
Cancer Institute [U54 CA164336, R01 CA160744-01A1]; Bill and Melinda
Gates Foundation [30505]; Cancer Council NSW, Australia
FX The work was partially supported by public grants from the European
Commission (7th Framework Programme grants HEALTH-F3-2010-242061,
PREHDICT and HEALTH-F2-2011-282562, HPV AHEAD), from the Instituto de
Salud Carlos III (Spanish Government) (grants FIS PI08/1535, FIS
PI10/02995, FIS PI11/02090, FIS PI11/02096, FIS PI11/02104, RCESP
C03/09, RTICESP C03/10, RTIC RD06/0020/0095, RD12/0036/0056 and
CIBERESP) and from the Agencia de Gestio d'Ajuts Universitaris i de
Recerca Generalitat de Catalunya (Catalonian Government) (grants AGAUR
2005SGR00695 and AGAUR 2009SGR126), who had no role in data collection,
analysis or interpretation of results. Thomas R. Broker receives
research support from the USPHS/NIH/National Cancer Institute (grants
"Human Papillomavirus Gene Expression" CA36200 and "Mechanisms of Human
Papillomavirus DNA Replication" CA83679). Anna-Barbara Moscicki's work
is supported by US Public Health Service grant R37 CA51323 (National
Cancer Institute, National Institutes of Health, Department of Health
and Human Services) and National Institute of AIDS and Infectious
Disease RC1 AI86051. John Doorbar is funded by the UK Medical Research
Council through program grant MC_U117584278 (Molecular Biology of Human
Papillomavirus Infection). Marc Arbyn received financial support from:
(1) the 7th Framework Programme of DG Research of the European
Commission through the PREHDICT project (grant No. 242061, coordinated
by the Vrije Universiteit Amsterdam, the Netherlands) and through the
HPV AHEAD Network (FP7-HEALTH-2011-282562); (2) the Belgian Foundation
Against Cancer (Brussels, Belgium); and (3) the International Agency for
Research on Cancer (Lyon, France). Jack Cuzick was supported in part by
Cancer Research UK programme grant A10404. Karen Canfell is supported by
grants from the National Health and Medical Research Council, Australia
(CDF APP1007994 and Project Grant #1007518), by non-commercial
government and academic consulting agreements in Australia, New Zealand
and the UK, and by Cancer Council NSW, Australia. Lynette A. Denny was
partially supported by Bill and Melinda Gates Foundation, USA (35537).
The work of Chris J.L.M. Meijer received support via the 7th Framework
Programme of DG Research of the European commission through the PREHDICT
project (grant 242061, coordinated via the Vrije Universiteit
Amsterdam). Jane J. Kim is supported in part by grants from the U.S.
National Cancer Institute (U54 CA164336, R01 CA160744-01A1) and the Bill
and Melinda Gates Foundation (30505) for modeling of HPV and cervical
cancer in developing countries.
NR 20
TC 15
Z9 20
U1 8
U2 42
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 31
PY 2013
VL 31
SU 7
BP H1
EP H31
DI 10.1016/j.vaccine.2013.10.003
PG 31
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 288HM
UT WOS:000329602600003
PM 24332295
ER
PT J
AU Bosch, FX
Broker, TR
Forman, D
Moscicki, AB
Gillison, ML
Doorbar, J
Stern, PL
Stanley, M
Arbyn, M
Poljak, M
Cuzick, J
Castle, PE
Schiller, JT
Markowitz, LE
Fisher, WA
Canfell, K
Denny, LA
Franco, EL
Steben, M
Kane, MA
Schiffman, M
Meijer, CJLM
Sankaranarayanan, R
Castellsague, X
Kim, JJ
Brotons, M
Alemany, L
Albero, G
Diaz, M
de Sanjose, S
AF Xavier Bosch, F.
Broker, Thomas R.
Forman, David
Moscicki, Anna-Barbara
Gillison, Maura L.
Doorbar, John
Stern, Peter L.
Stanley, Margaret
Arbyn, Marc
Poljak, Mario
Cuzick, Jack
Castle, Philip E.
Schiller, John T.
Markowitz, Lauri E.
Fisher, William A.
Canfell, Karen
Denny, Lynette A.
Franco, Eduardo L.
Steben, Marc
Kane, Mark A.
Schiffman, Mark
Meijer, Chris J. L. M.
Sankaranarayanan, Rengaswamy
Castellsague, Xavier
Kim, Jane J.
Brotons, Maria
Alemany, Laia
Albero, Ginesa
Diaz, Mireia
de Sanjose, Silvia
CA ICO Monograph 'Comprehensive Contr
TI Comprehensive Control of Human Papillomavirus Infections and Related
Diseases
SO VACCINE
LA English
DT Review
DE HPV; Cervical cancer; Anal cancer; Penile cancer; Vaginal cancer; Vulvar
cancer; Oropharyngeal cancer; Screening; HPV vaccination; HPV testing;
Prevention
ID CERVICAL-CANCER; PREVENTION; COUNTRIES; VACCINES; WORLD
AB Infection with human papillomavirus (HPV) is recognized as one of the major causes of infection-related cancer worldwide, as well as the causal factor in other diseases. Strong evidence for a causal etiology with HPV has been stated by the International Agency for Research on Cancer for cancers of the cervix uteri, penis, vulva, vagina, anus and oropharynx (including base of the tongue and tonsils). Of the estimated 12.7 million new cancers occurring in 2008 worldwide, 4.8% were attributable to HPV infection, with substantially higher incidence and mortality rates seen in developing versus developed countries. In recent years, we have gained tremendous knowledge about HPVs and their interactions with host cells, tissues and the immune system; have validated and implemented strategies for safe and efficacious prophylactic vaccination against HPV infections; have developed increasingly sensitive and specific molecular diagnostic tools for HPV detection for use in cervical cancer screening; and have substantially increased global awareness of HPV and its many associated diseases in women, men, and children. While these achievements exemplify the success of biomedical research in generating important public health interventions, they also generate new and daunting challenges: costs of HPV prevention and medical care, the implementation of what is technically possible, socio-political resistance to prevention opportunities, and the very wide ranges of national economic capabilities and health care systems. Gains and challenges faced in the quest for comprehensive control of HPV infection and HPV-related cancers and other disease are summarized in this review. The information presented may be viewed in terms of a reframed paradigm of prevention of cervical cancer and other HPV-related diseases that will include strategic combinations of at least four major components: 1) routine introduction of HPV vaccines to women in all countries, 2) extension and simplification of existing screening programs using HPV-based technology, 3) extension of adapted screening programs to developing populations, and 4) consideration of the broader spectrum of cancers and other diseases preventable by HPV vaccination in women, as well as in men. Despite the huge advances already achieved, there must be ongoing efforts including international advocacy to achieve widespread-optimally universal-implementation of HPV prevention strategies in both developed and developing countries.
This article summarizes information from the chapters presented in a special ICO Monograph 'Comprehensive Control of HPV Infections and Related Diseases' Vaccine Volume 30, Supplement 5, 2012. Additional details on each subtopic and full information regarding the supporting literature references may be found in the original chapters. (C) 2013 Elsevier Ltd. All rights reserved.
C1 [Xavier Bosch, F.; Castellsague, Xavier; Kim, Jane J.; Brotons, Maria; Alemany, Laia; Albero, Ginesa; Diaz, Mireia; de Sanjose, Silvia] IDIBELL, Catalan Inst Oncol ICO, Canc Epidemiol Res Program, Lhospitalet De Llobregat, Barcelona, Spain.
[Broker, Thomas R.] Univ Alabama Birmingham, Birmingham, AL USA.
[Forman, David] Int Agcy Res Canc, Sect Canc Informat, F-69372 Lyon, France.
[Moscicki, Anna-Barbara] Univ Calif San Francisco, Dept Pediat, Div Adolescent Med, San Francisco, CA USA.
[Gillison, Maura L.] Ohio State Univ, Ctr Comprehens Canc, Columbus, OH USA.
[Doorbar, John] Natl Inst Med Res, Div Virol, London NW7 1AA, England.
[Stern, Peter L.] Univ Manchester, Paterson Inst Canc Res, Manchester, Lancs, England.
[Stanley, Margaret] Univ Cambridge, Dept Pathol, Cambridge CB2 1QP, England.
[Arbyn, Marc] Sci Inst Publ Hlth, Canc Epidemiol Unit, Brussels, Belgium.
[Arbyn, Marc] Univ Antwerp, Lab Cell Biol & Histol, B-2020 Antwerp, Belgium.
[Poljak, Mario] Univ Ljubljana, Fac Med, Inst Microbiol & Immunol, Ljubljana, Slovenia.
[Cuzick, Jack] Queen Mary Univ London, Wolfson Inst Prevent Med, London, England.
[Castle, Philip E.] Global Canc Initiat, Chestertown, MD USA.
[Schiller, John T.] NCI, Ctr Canc Res, Bethesda, MD 20892 USA.
[Markowitz, Lauri E.] Ctr Dis Control & Prevent, Natl Ctr HIV Viral Hepatitis STD & TB Prevent, Atlanta, GA USA.
[Fisher, William A.] Univ Western Ontario, Dept Psychol, Social Sci Ctr, London, ON, Canada.
[Fisher, William A.] Univ Western Ontario, Dept Obstet & Gynaecol, Social Sci Ctr, London, ON, Canada.
[Canfell, Karen] Univ NSW, Prince Wales Clin Sch, Lowy Canc Res Ctr, Sydney, NSW, Australia.
[Canfell, Karen] NSW Canc Council, Canc Epidemiol Res Unit, Sydney, NSW, Australia.
[Denny, Lynette A.] Univ Cape Town, Groote Schuur Hosp, Dept Obstet & Gynaecol, ZA-7925 Cape Town, South Africa.
[Denny, Lynette A.] Univ Cape Town, Groote Schuur Hosp, Inst Infect Dis & Mol Med, ZA-7925 Cape Town, South Africa.
[Franco, Eduardo L.] McGill Univ, Div Canc Epidemiol, Montreal, PQ, Canada.
[Steben, Marc] Inst Natl Sante Publ Quebec, Montreal, PQ, Canada.
[Kane, Mark A.] Consultant Immunizat Policy, Mercer Isl, WA USA.
[Schiffman, Mark] NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
[Meijer, Chris J. L. M.] Vrije Univ Amsterdam Med Ctr, Dept Pathol, Amsterdam, Netherlands.
[Sankaranarayanan, Rengaswamy] Int Agcy Res Canc, Screening Grp, F-69372 Lyon, France.
[Castellsague, Xavier; Alemany, Laia; Albero, Ginesa; de Sanjose, Silvia] CIBER Epidemiol & Salud Publ CIBERESP, Madrid, Spain.
[Kim, Jane J.] Harvard Univ, Sch Publ Hlth, Dept Hlth Policy & Management, Ctr Hlth Decis Sci, Boston, MA 02115 USA.
RP Bosch, FX (reprint author), IDIBELL, Catalan Inst Oncol ICO, Canc Epidemiol Res Program, Lhospitalet De Llobregat, Barcelona, Spain.
EM admincerp@iconcologia.net
RI de Sanjose Llongueras, Silvia/H-6339-2014; Bruni, Laia/N-5816-2014;
BOSCH JOSE, FRANCESC XAVIER/J-6339-2012; Castellsague Pique,
Xavier/N-5795-2014; DIAZ SANCHIS, MIREIA/H-6335-2014; Albero,
Ginesa/G-7248-2015;
OI BOSCH JOSE, FRANCESC XAVIER/0000-0002-7172-3412; Castellsague Pique,
Xavier/0000-0002-0802-3595; Albero, Ginesa/0000-0002-9400-1914; Kjaer,
Susanne/0000-0002-8347-1398; Bruni, Laia/0000-0003-3943-0326; Franco,
Eduardo/0000-0002-4409-8084
FU European Commission [HEALTH-F3-2010-242061, HEALTH-F2-2011-282562];
Instituto de Salud Carlos III (Spanish Government) [FIS PI08/1535, FIS
PI10/02995, FIS PI11/02090, FIS PI11/02096, FIS PI11/02104, RCESP
C03/09, RTICESP C03/10, RTIC RD06/0020/0095, RD12/0036/0056, CIBERESP];
Agencia de Gestio d'Ajuts Universitaris i de Recerca - Generalitat de
Catalunya (Catalonian Government) [AGAUR 2005SGR00695, AGAUR
2009SGR126]; USPHS/NIH/National Cancer Institute [CA36200, CA83679]; US
Public Health Service grant (National Cancer Institute, National
Institutes of Health, Department of Health and Human Services) [R37
CA51323]; National Institute of AIDS and Infectious Disease [RC1
AI86051]; UK Medical Research Council [MC_U117584278]; European
Commission through the PREHDICT project [242061]; European Commission
through HPV AHEAD Network [FP7-HEALTH-2011-282562]; Belgian Foundation
Against Cancer (Brussels, Belgium); International Agency for Research on
Cancer (Lyon, France); Cancer Research UK [A10404]; National Health and
Medical Research Council, Australia [CDF APP1007994, 1007518]; Cancer
Council NSW, Australia; Bill and Melinda Gates Foundation, USA [35537];
U.S. National Cancer Institute [U54 CA164336, R01 CA160744-01A1]; Bill
and Melinda Gates Foundation [30505]
FX The work was partially supported by public grants from the European
Commission (7th Framework Programme grants HEALTH-F3-2010-242061,
PREHDICT and HEALTH-F2-2011-282562, HPV AHEAD), from the Instituto de
Salud Carlos III (Spanish Government) (grants FIS PI08/1535, FIS
PI10/02995, FIS PI11/02090, FIS PI11/02096, FIS PI11/02104, RCESP
C03/09, RTICESP C03/10, RTIC RD06/0020/0095, RD12/0036/0056 and
CIBERESP) and from the Agencia de Gestio d'Ajuts Universitaris i de
Recerca - Generalitat de Catalunya (Catalonian Government) (grants AGAUR
2005SGR00695 and AGAUR 2009SGR126), who had no role in data collection,
analysis or interpretation of results. Thomas R. Broker receives
research support from the USPHS/NIH/National Cancer Institute (grants
"Human Papillomavirus Gene Expression" CA36200 and "Mechanisms of Human
Papillomavirus DNA Replication" CA83679). Anna-Barbara Moscicki's work
is supported by US Public Health Service grant R37 CA51323 (National
Cancer Institute, National Institutes of Health, Department of Health
and Human Services) and National Institute of AIDS and Infectious
Disease RC1 AI86051. John Doorbar is funded by the UK Medical Research
Council through program grant MC_U117584278 (Molecular Biology of Human
Papillomavirus Infection). Marc Arbyn received financial support from:
(1) the 7th Framework Programme of DG Research of the European
Commission through the PREHDICT project (grant No. 242061, coordinated
by the Vrije Universiteit Amsterdam, the Netherlands) and through the
HPV AHEAD Network (FP7-HEALTH-2011-282562); (2) the Belgian Foundation
Against Cancer (Brussels, Belgium); and (3) the International Agency for
Research on Cancer (Lyon, France). Jack Cuzick was supported in part by
Cancer Research UK programme grant A10404. Karen Canfell is supported by
grants from the National Health and Medical Research Council, Australia
(CDF APP1007994 and Project Grant #1007518), by non-commercial
government and academic consulting agreements in Australia, New Zealand
and the UK, and by Cancer Council NSW, Australia. Lynette A. Denny was
partially supported by Bill and Melinda Gates Foundation, USA (35537).
The work of Chris J.L.M. Meijer received support via the 7th Framework
Programme of DG Research of the European commission through the PREHDICT
project (grant 242061, coordinated via the Vrije Universiteit
Amsterdam). Jane J. Kim is supported in part by grants from the U.S.
National Cancer Institute (U54 CA164336, R01 CA160744-01A1) and the Bill
and Melinda Gates Foundation (30505) for modeling of HPV and cervical
cancer in developing countries.
NR 20
TC 0
Z9 1
U1 1
U2 16
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 30
PY 2013
VL 31
SU 6
BP G1
EP G31
DI 10.1016/j.vaccine.2013.10.002
PG 31
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 289LR
UT WOS:000329684500003
PM 24331817
ER
PT J
AU Parashar, UD
Nelson, EAS
Kang, G
AF Parashar, Umesh D.
Nelson, E. Anthony S.
Kang, Gagandeep
TI Diagnosis, management, and prevention of rotavirus gastroenteritis in
children
SO BMJ-BRITISH MEDICAL JOURNAL
LA English
DT Editorial Material
ID PLACEBO-CONTROLLED TRIAL; CLINICAL SEVERITY; SEVERE DIARRHEA;
RISK-FACTORS; VACCINE; INFECTION; INTUSSUSCEPTION; INFANTS;
HOSPITALIZATION; MEXICO
C1 [Parashar, Umesh D.] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
[Nelson, E. Anthony S.] Chinese Univ Hong Kong, Dept Paediat, Hong Kong, Hong Kong, Peoples R China.
[Kang, Gagandeep] Christian Med Coll & Hosp, Div Gastrointestinal Sci, Vellore 632004, Tamil Nadu, India.
RP Parashar, UD (reprint author), Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
EM uap2@cdc.gov
OI Nelson, Edmund Anthony Severn/0000-0002-2521-3403
NR 69
TC 14
Z9 14
U1 0
U2 7
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 1756-1833
J9 BMJ-BRIT MED J
JI BMJ-British Medical Journal
PD DEC 30
PY 2013
VL 347
AR f7204
DI 10.1136/bmj.f7204
PG 10
WC Medicine, General & Internal
SC General & Internal Medicine
GA 285PM
UT WOS:000329406100001
PM 24379214
ER
PT J
AU Bosch, FX
Broker, TR
Forman, D
Moscicki, AB
Gillison, ML
Doorbar, J
Stern, PL
Stanley, M
Arbyn, M
Poljak, M
Cuzick, J
Castle, PE
Schiller, JT
Markowitz, LE
Fisher, WA
Canfell, K
Denny, LA
Franco, EL
Steben, M
Kane, MA
Schiffman, M
Meijer, CJLM
Sankaranarayanan, R
Castellsague, X
Kim, JJ
Brotons, M
Alemanya, L
Albero, G
Diaz, M
de Sanjose, S
AF Bosch, F. Xavier
Broker, Thomas R.
Forman, David
Moscicki, Anna-Barbara
Gillison, Maura L.
Doorbar, John
Stern, Peter L.
Stanley, Margaret
Arbyn, Marc
Poljak, Mario
Cuzick, Jack
Castle, Philip E.
Schiller, John T.
Markowitz, Lauri E.
Fisher, William A.
Canfell, Karen
Denny, Lynette A.
Franco, Eduardo L.
Steben, Marc
Kane, Mark A.
Schiffman, Mark
Meijer, Chris J. L. M.
Sankaranarayanan, Rengaswamy
Castellsague, Xavier
Kim, Jane J.
Brotons, Maria
Alemanya, Laia
Albero, Ginesa
Diaz, Mireia
de Sanjose, Silvia
CA ICO Monograph Comprehensive Contro
TI Comprehensive Control of Human Papillomavirus Infections and Related
Diseases
SO VACCINE
LA English
DT Review
DE HPV; Cervical cancer; Anal cancer; Penile cancer; Vaginal cancer; Vulvar
cancer; Oropharyngeal cancer; Screening; HPV vaccination; HPV testing;
Prevention
ID CERVICAL-CANCER; PREVENTION; COUNTRIES; VACCINES; WORLD
AB Infection with human papillomavirus (HPV) is recognized as one of the major causes of infection-related cancer worldwide, as well as the causal factor in other diseases. Strong evidence for a causal etiology with HPV has been stated by the International Agency for Research on Cancer for cancers of the cervix uteri, penis, vulva, vagina, anus and oropharynx (including base of the tongue and tonsils). Of the estimated 12.7 million new cancers occurring in 2008 worldwide, 4.8% were attributable to HPV infection, with substantially higher incidence and mortality rates seen in developing versus developed countries. In recent years, we have gained tremendous knowledge about HPVs and their interactions with host cells, tissues and the immune system; have validated and implemented strategies for safe and efficacious prophylactic vaccination against HPV infections; have developed increasingly sensitive and specific molecular diagnostic tools for HPV detection for use in cervical cancer screening; and have substantially increased global awareness of HPV and its many associated diseases in women, men, and children. While these achievements exemplify the success of biomedical research in generating important public health interventions, they also generate new and daunting challenges: costs of HPV prevention and medical care, the implementation of what is technically possible, socio-political resistance to prevention opportunities, and the very wide ranges of national economic capabilities and health care systems. Gains and challenges faced in the quest for comprehensive control of HPV infection and HPV-related cancers and other disease are summarized in this review. The information presented may be viewed in terms of a reframed paradigm of prevention of cervical cancer and other HPV-related diseases that will include strategic combinations of at least four major components: 1) routine introduction of HPV vaccines to women in all countries, 2) extension and simplification of existing screening programs using HPV-based technology, 3) extension of adapted screening programs to developing populations, and 4) consideration of the broader spectrum of cancers and other diseases preventable by HPV vaccination in women, as well as in men. Despite the huge advances already achieved, there must be ongoing efforts including international advocacy to achieve widespread-optimally universal-implementation of HPV prevention strategies in both developed and developing countries.
This article summarizes information from the chapters presented in a special ICO Monograph 'Comprehensive Control of HPV Infections and Related Diseases' Vaccine Volume 30, Supplement 5, 2012. Additional details on each subtopic and full information regarding the supporting literature references may be found in the original chapters. (C) 2013 Elsevier Ltd. All rights reserved.
C1 [Bosch, F. Xavier; Castellsague, Xavier; Brotons, Maria; Alemanya, Laia; Albero, Ginesa; Diaz, Mireia; de Sanjose, Silvia] IDIBELL, Inst Catala Oncol Catalan Inst Oncol ICO, Canc Epidemiol Res Program, Lhospitalet De Llobregat, Barcelona, Spain.
[Broker, Thomas R.] Univ Alabama Birmingham, Birmingham, AL USA.
[Forman, David] Int Agcy Res Canc, Sect Canc Informat, F-69372 Lyon, France.
[Moscicki, Anna-Barbara] Univ Calif San Francisco, Dept Pediat, Div Adolescent Med, San Francisco, CA USA.
[Gillison, Maura L.] Ohio State Univ, Ctr Comprehens Canc, Columbus, OH 43210 USA.
[Doorbar, John] Natl Inst Med Res, Div Virol, London NW7 1AA, England.
[Stern, Peter L.] Univ Manchester, Paterson Inst Canc Res, Manchester, Lancs, England.
[Stanley, Margaret] Univ Cambridge, Dept Pathol, Cambridge CB2 1QP, England.
[Arbyn, Marc] Sci Inst Publ Hlth, Canc Epidemiol Unit, Brussels, Belgium.
[Arbyn, Marc] Univ Antwerp, Lab Cell Biol & Histol, B-2020 Antwerp, Belgium.
[Poljak, Mario] Univ Ljubljana, Fac Med, Inst Microbiol & Immunol, Ljubljana, Slovenia.
[Cuzick, Jack] Queen Mary Univ London, Wolfson Inst Prevent Med, London, England.
[Castle, Philip E.] Global Canc Initiat, Chestertown, MD USA.
[Schiller, John T.] NCI, Ctr Canc Res, Bethesda, MD 20892 USA.
[Markowitz, Lauri E.] Ctr Dis Control & Prevent, Natl Ctr HIV Viral Hepatitis STD & TB Prevent, Atlanta, GA USA.
[Fisher, William A.] Univ Western Ontario, Dept Psychol, Social Sci Ctr, London, ON, Canada.
[Fisher, William A.] Univ Western Ontario, Dept Obstet & Gynaecol, Social Sci Ctr, London, ON, Canada.
[Canfell, Karen] Univ NSW, Prince Wales Clin Sch, Lowy Canc Res Ctr, Sydney, NSW, Australia.
[Canfell, Karen] NSW Canc Council, Canc Epidemiol Res Unit, Sydney, NSW, Australia.
[Denny, Lynette A.] Univ Cape Town, Dept Obstet & Gynaecol, Groote Schuur Hosp, Cape Town, South Africa.
[Denny, Lynette A.] Univ Cape Town, Inst Infect Dis & Mol Med, Groote Schuur Hosp, Cape Town, South Africa.
[Franco, Eduardo L.] McGill Univ, Div Canc Epidemiol, Montreal, PQ, Canada.
[Steben, Marc] Inst Natl Sante Publ Quebec, Montreal, PQ, Canada.
[Schiffman, Mark] NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
[Meijer, Chris J. L. M.] Vrije Univ Amsterdam Med Ctr, Dept Pathol, Amsterdam, Netherlands.
[Sankaranarayanan, Rengaswamy] Int Agcy Res Canc, Screening Grp, F-69372 Lyon, France.
[Castellsague, Xavier; Alemanya, Laia; Albero, Ginesa; de Sanjose, Silvia] CIBER Epidemiol & Salud Publ CIBERESP, Madrid, Spain.
[Kim, Jane J.] Harvard Univ, Sch Publ Hlth, Dept Hlth Policy & Management, Ctr Hlth Decis Sci, Boston, MA 02115 USA.
RP Bosch, FX (reprint author), IDIBELL, Inst Catala Oncol Catalan Inst Oncol ICO, Canc Epidemiol Res Program, Lhospitalet De Llobregat, Barcelona, Spain.
EM admincerp@iconcologia.net
RI Castellsague Pique, Xavier/N-5795-2014; de Sanjose Llongueras,
Silvia/H-6339-2014; BOSCH JOSE, FRANCESC XAVIER/J-6339-2012; DIAZ
SANCHIS, MIREIA/H-6335-2014; Albero, Ginesa/G-7248-2015;
OI Castellsague Pique, Xavier/0000-0002-0802-3595; BOSCH JOSE, FRANCESC
XAVIER/0000-0002-7172-3412; Albero, Ginesa/0000-0002-9400-1914; Franco,
Eduardo/0000-0002-4409-8084
FU European Commission [HEALTH-F3-2010-242061, HEALTH-F2-2011-282562];
Instituto de Salud Carlos III (Spanish Government) [FIS PI08/1535, FIS
PI10/02995, FIS PI11/02090, FIS PI11/02096, FIS PI11/02104, RCESP
C03/09, RTICESP C03110, RTIC RD06/0020/0095, RD12/0036/0056, CIBERESP];
Agenda de Gestio d'Ajuts Universitaris i de Recerca - Generalitat de
Catalunya (Catalonian Government) [AGAUR 2005SGR00695, AGAUR
2009SGR126]; USPHS/NIH/National Cancer Institute [CA36200, CA83679]; US
Public Health Service (National Cancer Institute, National Institutes of
Health, Department of Health and Human Services) [R37 CA51323]; National
Institute of AIDS and Infectious Disease [RC1 AI86051]; UK Medical
Research Council [MC_U117584278]; European Commission through PREHDICT
[242061]; European Commission through HPV AHEAD Network
[FP7-HEALTH-2011-282562]; Belgian Foundation Against Cancer (Brussels,
Belgium); International Agency for Research on Cancer (Lyon, France);
Cancer Research UK [A10404]; National Health and Medical Research
Council, Australia [CDF APP1007994, 1007518]; non-commercial government
and academic consulting agreements in Australia, New Zealand;
non-commercial government and academic consulting agreements in
Australia, New Zealand, UK; Cancer Council NSW, Australia; Bill and
Melinda Gates Foundation, USA [35537]; U.S. National Cancer Institute
[U54 CA164336, R01 CA160744-01A1]; Bill and Melinda Gates Foundation
[30505]
FX The work was partially supported by public grants from the European
Commission (7th Framework Programme grants HEALTH-F3-2010-242061,
PREHDICT and HEALTH-F2-2011-282562, HPV AHEAD), from the Instituto de
Salud Carlos III (Spanish Government) (grants FIS PI08/1535, FIS
PI10/02995, FIS PI11/02090, FIS PI11/02096, FIS PI11/02104, RCESP
C03/09, RTICESP C03110, RTIC RD06/0020/0095, RD12/0036/0056 and
CIBERESP) and from the Agenda de Gestio d'Ajuts Universitaris i de
Recerca - Generalitat de Catalunya (Catalonian Government) (grants AGAUR
2005SGR00695 and AGAUR 2009SGR126), who had no role in data collection,
analysis or interpretation of results. Thomas R. Broker receives
research support from the USPHS/NIH/National Cancer Institute (grants
"Human Papillomavirus Gene Expression" CA36200 and "Mechanisms of Human
Papillomavirus DNA Replication" CA83679). Anna-Barbara Moscicki's work
is supported by US Public Health Service grant R37 CA51323 (National
Cancer Institute, National Institutes of Health, Department of Health
and Human Services) and National Institute of AIDS and Infectious
Disease RC1 AI86051. John Doorbar is funded by the UK Medical Research
Council through program grant MC_U117584278 (Molecular Biology of Human
Papillomavirus Infection). Marc Arbyn received financial support from:
(1) the 7th Framework Programme of DG Research of the European
Commission through the PREHDICT project (grant No. 242061, coordinated
by the Vrije Universiteit Amsterdam, the Netherlands) and through the
HPV AHEAD Network (FP7-HEALTH-2011-282562); (2) the Belgian Foundation
Against Cancer (Brussels, Belgium); and (3) the International Agency for
Research on Cancer (Lyon, France). Jack Cuzick was supported in part by
Cancer Research UK programme grant A10404. Karen Canfell is supported by
grants from the National Health and Medical Research Council, Australia
(CDF APP1007994 and Project Grant #1007518), by non-commercial
government and academic consulting agreements in Australia, New Zealand
and the UK, and by Cancer Council NSW, Australia. Lynette A. Denny was
partially supported by Bill and Melinda Gates Foundation, USA (35537).
The work of Chris J.L.M. Meijer received support via the 7th Framework
Programme of DG Research of the European commission through the PREHDICT
project (grant 242061, coordinated via the Vrije Universiteit
Amsterdam). Jane J. Kim is supported in part by grants from the U.S.
National Cancer Institute (U54 CA164336, R01 CA160744-01A1) and the Bill
and Melinda Gates Foundation (30505) for modeling of HPV and cervical
cancer in developing countries.
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PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 29
PY 2013
VL 31
SU 5
BP F1
EP F31
DI 10.1016/j.vaccine.2013.10.001
PG 31
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 289LQ
UT WOS:000329684400003
PM 24331745
ER
PT J
AU Averhoff, F
Kolwaite, A
Ward, JW
AF Averhoff, Francisco
Kolwaite, Amy
Ward, John W.
TI The role of the GAVI Alliance in improving childhood hepatitis B
vaccination in China: Successes, lessons learned, and future global
challenges
SO VACCINE
LA English
DT Editorial Material
ID MORTALITY; DISEASE; BURDEN; VIRUS; DEATH
C1 [Averhoff, Francisco; Kolwaite, Amy; Ward, John W.] Ctr Dis Control & Prevent, Div Viral Hepatitis, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA 30329 USA.
[Kolwaite, Amy] Ctr Dis Control & Prevent, Sci Educ & Profess Dev Program Off, Atlanta, GA 30329 USA.
RP Averhoff, F (reprint author), Ctr Dis Control & Prevent, Div Viral Hepatitis, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA 30329 USA.
EM fma0@cdc.gov
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PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 27
PY 2013
VL 31
SU 9
BP J5
EP J7
DI 10.1016/j.vaccine.2013.04.022
PG 3
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 289MA
UT WOS:000329685400004
PM 23623862
ER
PT J
AU Cui, FQ
Drobeniuc, J
Hadler, SC
Hutin, YJ
Ma, FB
Wiersma, S
Wang, FZ
Wu, J
Zheng, H
Zhou, LW
Zuo, SY
AF Cui, Fuqiang
Drobeniuc, Jan
Hadler, Stephen C.
Hutin, Yvan J.
Ma, Fubao
Wiersma, Steve
Wang, Fuzhen
Wu, Jiang
Zheng, Hui
Zhou, Liwei
Zuo, Shuyan
TI Review of hepatitis B surveillance in China: Improving information to
frame future directions in prevention and control
SO VACCINE
LA English
DT Review
DE Hepatitis B; Surveillance evaluation; China; Laboratory diagnosis
ID CHILDREN; ANTIGEN; TAIWAN
AB Background: As the WHO verified that China reached the target of 1% prevalence of chronic hepatitis B infection among children targeted by universal hepatitis B immunization of newborns, the country considered new options for hepatitis B prevention and control. We reviewed hepatitis B surveillance in the broader context of viral hepatitis surveillance to propose recommendations to improve the system.
Methods: We described surveillance for viral hepatitis in China with a specific focus on hepatitis B. We assessed critical attributes of the system, including data quality, predictive positive value and usefulness.
Results: While remarkable progress in hepatitis B immunization of infants and children has likely almost eliminated transmission in younger age groups, reported rates of hepatitis B increased steadily in China between 1990 and 2008, probably because of a failure to distinguish acute from chronic infections. Elements that prevented a clearer separation between acute and chronic cases included (1) missed opportunity to report cases accurately among clinicians, (2) low availability and use of tests to detect IgM against the hepatitis B core antigen (IgM anti-HBc) and (3) lack of systems to sort, manage and analyze surveillance data.
Conclusions: To improve hepatitis B surveillance, China may consider (1) training clinicians to diagnose acute cases and to use IgM anti-HBc to confirm them, (2) improving access and use of validated IgM anti-HBc tests and (3) developing data management and analysis techniques that sort out acute from chronic cases. (C) 2013 Elsevier Ltd. All rights reserved.
C1 [Cui, Fuqiang; Wang, Fuzhen; Zheng, Hui] China Ctr Dis Control CDC, Beijing, Peoples R China.
[Drobeniuc, Jan] Ctr Dis Control & Prevent, Hepatitis Div, Atlanta, GA USA.
[Hadler, Stephen C.; Hutin, Yvan J.; Zuo, Shuyan] WHO, China Country Off, Beijing, Peoples R China.
[Ma, Fubao] Jiangsu Ctr Dis Control CDC, Nanjing, Jiangsu, Peoples R China.
[Wiersma, Steve] World Hlth Org Headquarters, Geneva, Switzerland.
[Wu, Jiang] Beijing Ctr Dis Control CDC, Beijing, Peoples R China.
[Zhou, Liwei] Ningxia Ctr Dis Control CDC, Yinchuan, Peoples R China.
RP Hutin, YJ (reprint author), WHO, China Country Off, Beijing, Peoples R China.
EM yvan.hutin@ecdc.europa.eu
FU United States Centers for Disease Control and Prevention; Zeshan
Foundation (Hong Kong); WHO
FX We are grateful to Alicia Barrasa, Erika Duffel, Michael Edelstein, Dale
Hu, Lance Rodewald and Nicole Seguy for critical comments on the
manuscript. This work benefited from funding support from the United
States Centers for Disease Control and Prevention, from the Zeshan
Foundation (Hong Kong) and from the WHO.
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PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 27
PY 2013
VL 31
SU 9
BP J79
EP J84
DI 10.1016/j.vaccine.2013.05.054
PG 6
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 289MA
UT WOS:000329685400016
PM 23770336
ER
PT J
AU Cui, FQ
Liang, XF
Gong, XH
Chen, YS
Wang, FZ
Zheng, H
Wu, ZH
Miao, N
Hadler, SC
Hutin, YJ
Luo, HM
Yang, WZ
AF Cui, Fuqiang
Liang, Xiaofeng
Gong, Xiaohong
Chen, Yuansheng
Wang, Fuzhen
Zheng, Hui
Wu, Zhenhua
Miao, Ning
Hadler, Stephen C.
Hutin, Yvan J.
Luo, Huiming
Yang, Weizhong
TI Preventing hepatitis B though universal vaccination: Reduction of
inequalities through the GAVI China project
SO VACCINE
LA English
DT Article
ID HEALTH; COVERAGE; EQUITY; PROGRESS
AB Objective: In order to measure hepatitis B coverage and progress in equality with respect to protection against hepatitis B in poverty-affected areas funded by the Global Alliance on Vaccine and Immunization project funded in poverty-affected counties.
Methods: We reviewed routinely reported coverage data and conducted a national stratified, validation, cross-sectional survey in October 2010, according to WHO recommended sampling method. First, we stratified China into three regions (Eastern, Central and Western) based on economic criteria. Second, in each region, we selected eight counties with a probability proportional to population size. Third, in each selected county, we selected (a) 10 townships at random among the list of townships of the county.
Results: We visited 244 townships as part of the final evaluation (71 in the East, 86 in the Center and 87 in the West). Overall, in these 244 townships, surveyed TBD coverage increased from 60% in 2002 to 91% in 2009 and surveyed three dose of hepatitis B vaccine coverage increased from 71% in 2002 to 93% in 2009. Overall, in the GAVI supported areas, the HepB3/DTP3 ratio increased from 57% in 2002 to 94% in 2009.
Conclusion: Pro-poor GAVI approach was an effective way to reduce inequity among children through provision of free vaccination. When vaccine and AD syringes were provided for free, they closed the gap between Eastern and Western regions and between the rich and the poor. (C) 2012 Elsevier Ltd. All rights reserved.
C1 [Cui, Fuqiang; Liang, Xiaofeng; Gong, Xiaohong; Chen, Yuansheng; Wang, Fuzhen; Zheng, Hui; Wu, Zhenhua; Miao, Ning; Luo, Huiming; Yang, Weizhong] Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China.
[Hadler, Stephen C.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Hutin, Yvan J.] World Hlth Org Off China, Beijing, Peoples R China.
RP Yang, WZ (reprint author), Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China.
EM Yangwz@chinacdc.cn
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SN 0264-410X
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J9 VACCINE
JI Vaccine
PD DEC 27
PY 2013
VL 31
SU 9
BP J29
EP J35
DI 10.1016/j.vaccine.2012.07.048
PG 7
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 289MA
UT WOS:000329685400008
PM 24331017
ER
PT J
AU Cui, FQ
Luo, HM
Wang, FZ
Zheng, H
Gong, XH
Chen, YS
Wu, ZH
Miao, N
Kane, M
Hennessey, K
Hadler, SC
Hutin, YJ
Liang, XF
Yang, WZ
AF Cui, Fuqiang
Luo, Huiming
Wang, Fuzhen
Zheng, Hui
Gong, Xiaohong
Chen, Yuansheng
Wu, Zhenhua
Miao, Ning
Kane, Mark
Hennessey, Karen
Hadler, Stephen C.
Hutin, Yvan J.
Liang, Xiaofeng
Yang, Weizhong
TI Evaluation of policies and practices to prevent mother to child
transmission of hepatitis B virus in China: Results from China GAVI
project final evaluation
SO VACCINE
LA English
DT Article
DE Hepatitis B; Transmission; GAVI; Project; Evaluation
ID NEWBORN-INFANTS; UNITED-STATES; VACCINATION; IMMUNIZATION; INFECTION;
STRATEGY; IMPACT
AB Background: Mother to Child Transmission (MTCT) has remained a leading cause of HBV infection in China, accounting for 40% of total infections. Providing hepatitis B vaccine (HepB) to all infants within 24 h of birth (Timely Birth Dose, TBD), and subsequent completion of at least 3 vaccine doses is key to preventing perinatal HBV infection. In 2002, with the financial support of the Global Alliance on Vaccine and Immunization (GAVI) targeted to Western region and 223 poverty-affected counties in Central region, hepatitis B vaccine was provided for free. In 2010, we evaluated the China GAVI project in terms of its activities to prevent perinatal infections.
Objective: The objectives of the evaluation were to (1) measure achievements in the China GAVI project in terms of TBD coverage, and (2) describe practices for HBsAg screening of pregnant women and HBIG use outside the GAVI China project.
Methods: We used the methods recommended by WHO to select a cluster sample of health care facilities for the purpose of an injection safety assessment. We stratified China into three regions based on economic criteria, and selected eight counties with a probability proportional to population size in each region. In each selected county, we selected (a) 10 townships at random among the list of townships of the county and (b) the one county level hospital. In each hospital, we abstracted 2002 through 2009 records to collect information regarding birth cohorts, hospitals deliveries, vaccine management, hepatitis B vaccination delivery, HBsAg screening practices and results, and HBIG administration. In addition, in all hospitals, we abstracted records regarding the delivery of TBD.
Results: We visited 244 facilities in the three regions, including 24 county hospitals and 220 township hospitals. We reviewed 837,409 birth summary records, 699,249 for infants born at county or township hospitals. Hospital delivery rates increased from 58% in 2002 to 93% in 2009. Surveyed TBD coverage increased from 60% in 2002 to 91% in 2009 (+31%). Surveyed TBD coverage among children born in hospitals increased from 73% in 2002 to 98% in 2009. Between 2002 and 2009, the proportion of pregnant women screened for HBsAg increased from 64% in 2002 to 85% in 2009. In 2009, the proportion of infants born to women screened and found to be HBsAg positive who did not receive any immunization within 24 h after birth ranged from 0% to 0.7% across regions.
Conclusions: Increased availability of hepatitis B vaccine, along with efforts to improve hospital deliveries, increased TBD coverage in China. This decreased perinatal HBV transmission and will reduce disease burden in the future. Screening for HBsAg to guide HBIG administration has begun, but with heterogeneous immuno-prophylaxis practices and a poor system for follow up. (C) 2012 Elsevier Ltd. All rights reserved.
C1 [Cui, Fuqiang; Luo, Huiming; Wang, Fuzhen; Zheng, Hui; Gong, Xiaohong; Chen, Yuansheng; Wu, Zhenhua; Miao, Ning; Liang, Xiaofeng; Yang, Weizhong] Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China.
[Hennessey, Karen] WHO, Manila, Philippines.
[Hadler, Stephen C.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Hutin, Yvan J.] World Hlth Org Off China, Beijing, Peoples R China.
RP Yang, WZ (reprint author), Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China.
EM Yangwz@chinacdc.cn
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PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 27
PY 2013
VL 31
SU 9
BP J36
EP J42
DI 10.1016/j.vaccine.2012.11.061
PG 7
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 289MA
UT WOS:000329685400009
PM 24331019
ER
PT J
AU Hadler, SC
Cui, FQ
Averhoff, F
Taylor, T
Wang, FZ
Li, L
Liang, XF
Yang, WZ
AF Hadler, Stephen C.
Cui Fuqiang
Averhoff, Francisco
Taylor, Thomas
Wang Fuzhen
Li, Li
Liang Xiaofeng
Yang Weizhong
TI The impact of hepatitis B vaccine in China and in the China GAVI Project
SO VACCINE
LA English
DT Article
DE Hepatitis B; Surveillance evaluation; China; Laboratory diagnosis
ID C VIRUS-INFECTIONS; HEPATOCELLULAR-CARCINOMA; LIVER-CANCER; CHILDREN;
POPULATION; PROGRAM; TAIWAN
AB The China GAVI Project (CGP) was initiated in 2002 to provide hepatitis B (HB) vaccine to infants born in the less developed areas of China including the Western provinces and poverty counties of Middle provinces, to prevent the consequences of hepatitis B virus infection. By 2009, the project areas had raised coverage of 3 doses of HB vaccine and timely birth doses to almost 90% among infants, comparable to those in wealthier Eastern provinces, and reduced HBV prevalence to <1% among children in these areas. We estimated the impact in disease prevented by HB vaccine in China between 1992, when the vaccine was routinely recommended, and 2009, and in CGP areas for the years 2003-2009, when the CGP was active. A published model was used to estimate the burden of chronic and acute HBV infection and death prevented due to HB vaccination in China and the CGP areas using data from national serosurveys in China in 1992 and 2006, and HB vaccine coverage from surveys in 2004, 2006 and 2010. We used sigmoid modeling to estimate vaccine coverage nationally, regionally, and CGP areas. We also estimated the incremental impact of the CGP on HB vaccine coverage in those underserved areas. Our findings suggest that between 1992 and 2009, HB vaccination in China has prevented 24 million chronic HBV infections and 4.3 million future deaths due to cirrhosis, hepatocellular carcinoma and acute hepatitis. During the CGP between 2003 and 2009, an estimated 3.8 million chronic HBV infections and 680,000 deaths were prevented in CGP areas. We found that the CGP funding increased HB vaccine coverage in project areas by 4-15% for HB3 and 4-27% for timely birth dose beyond the coverage expected without the CGP. The CGP represents a highly successful public health collaboration between the national government and international partners. Published by Elsevier Ltd.
C1 [Hadler, Stephen C.; Taylor, Thomas] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Infect, Div Bacterial Dis, Atlanta, GA USA.
[Cui Fuqiang; Wang Fuzhen; Li, Li; Liang Xiaofeng; Yang Weizhong] China Ctr Dis Control & Prevent, Natl Immunizat Program, Beijing, Peoples R China.
[Averhoff, Francisco] Ctr Dis Control & Prevent, Natl Ctr HIV AIDs Hepatitis Sexually Transmitted, Div Viral Hepatitis, Atlanta, GA USA.
RP Hadler, SC (reprint author), Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Infect, Div Bacterial Dis, Atlanta, GA USA.
EM sch1@cdc.gov
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PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 27
PY 2013
VL 31
SU 9
BP J66
EP J72
DI 10.1016/j.vaccine.2013.03.043
PG 7
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 289MA
UT WOS:000329685400014
PM 24331023
ER
PT J
AU Kane, MA
Hadler, SC
Lee, L
Shapiro, CN
Cui, F
Wang, X
Kumar, R
AF Kane, M. A.
Hadler, S. C.
Lee, L.
Shapiro, C. N.
Cui, F.
Wang, X.
Kumar, R.
TI The inception, achievements, and implications of the China GAVI Alliance
Project on Hepatitis B Immunization
SO VACCINE
LA English
DT Review
ID NEWBORN-INFANTS; TRANSMISSION; VACCINATION
AB The China GAVI Hepatitis B Immunization Project was initiated in 2002 with the signing of a Memorandum of Understanding between GAVI and the Government of China. The Project was one of the three (China, India, and Indonesia) GAVI-initiated special projects done to support countries too large to receive full GAVI support for hepatitis B vaccine and safe injections. The Project in China was designed by the Chinese Government and partners to deliver free hepatitis B vaccine and safe injections to all newborns in the 12 Western Provinces and Poverty Counties in 10 Provinces of Central China (1301 Counties with approximately 5.6 million births per year), eliminating the gap in immunization coverage between wealthier and poorer regions of China. The project budget (USD 76 million) was equally shared by GAVI and the Chinese Government. Initially planned for 5 years, two no cost extensions extended the project to 2011. Although China produced hepatitis B vaccine, before the project the vaccine was sold to parents who were also charged a "user fee" for the syringe and vaccine administration. Basic Expanded Program on Immunization (EPI) vaccines such as BCG, DTP, Polio, and measles vaccines were provided free to parents, although they were charged a user fee. Vaccines were sold by China CDC Offices at provincial, prefecture, county level and township hospitals, and village doctors received a substantial portion of their income from the sale of hepatitis B and other vaccines. The result of charging for hepatitis B vaccine was that coverage was relatively high in Eastern and wealthier counties in Central China (similar to 80-90%), but was much lower (similar to 40%) in Western China and Poverty Counties where parents could not afford the vaccine. The Project was administered by the China MOH and China CDC EPI program, and two Project Co-managers, one from the Chinese Government and the other an international assignee, were chosen. The project had an oversight Operational Advisory Group composed of the Chinese Government, WHO, UNICEF, and GAVI.
The initial targets of the project as delineated in the initial MOU for the Project areas (HepB3 coverage will reach 85% at the county level, >75% of newborns at the county level will receive the first dose of hepatitis B within 24 h of birth, and all immunization injections will be with auto disable [AD] syringes) were substantially exceeded. The differential in vaccine coverage between wealthier and poorer parts of China was eliminated contributing to a great improvement inequity. With additional contributions of the Chinese Government the Project was accomplished substantially under budget allowing for additional catch up immunization of children under 15 years of age. More than 5 million health workers were trained in how to deliver hepatitis B vaccine, timely birth dose (TBD), and safe injections, and public awareness of hepatitis B and its prevention rose significantly. TBD coverage was expedited by concurrent efforts to have women deliver in township clinics and district hospitals instead of at home. The effective management of the Project, with a Project office sitting within the China EPI and an Operational Advisory Group for oversight, could serve as a model for other GAVI projects worldwide. Most importantly, the carrier rate in Chinese children less than 5 years of age has fallen to 1%, from a level of 10% before the inception of the Project. Liver cancer, one of the major cancer killers in China (250,000-300,000 annual estimated deaths), will dramatically decline as immunized cohorts of Chinese children age. While hepatitis C and non-alcoholic liver disease also exist in China and can lead to liver cancer and cirrhosis, the majority of liver disease in China is hepatitis B related and therefore preventable. The authors believe that China's success in preventing hepatitis B is one of the greatest public health achievements of the 21st century.
Work remains to be done in several key areas. There are still pockets of home births in rural provinces where a TBD is difficult to deliver, and China is strengthening its policy of screening pregnant women for HBsAg and delivering HBIG plus vaccine to newborns of HBV carrier mothers. Approximately 10% of the adult population of China remain chronic carriers of hepatitis B virus and cannot be helped by the vaccine, so prevention of liver cancer and cirrhosis in those groups remains a future challenge for China. (C) 2013 Published by Elsevier Ltd.
C1 [Hadler, S. C.] NCIRD, Div Bacterial Dis, Ctr Dis Control & Prevent, Atlanta, GA USA.
[Shapiro, C. N.] US Dept HHS, Off Global Affairs, Washington, DC 20201 USA.
[Cui, F.] Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China.
[Wang, X.] WHO, Reg Off Western Pacific Manila, Manila, Philippines.
[Kumar, R.] GAVI Alliance, Geneva, Switzerland.
EM mark.a.kane@gmail.com
NR 25
TC 6
Z9 7
U1 1
U2 19
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 27
PY 2013
VL 31
SU 9
BP J15
EP J20
DI 10.1016/j.vaccine.2013.03.045
PG 6
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 289MA
UT WOS:000329685400006
PM 24331015
ER
PT J
AU Liang, XF
Cui, FQ
Hadler, S
Wang, XJ
Luo, HM
Chen, YS
Kane, M
Shapiro, C
Yang, WZ
Wang, Y
AF Liang, Xiaofeng
Cui, Fuqiang
Hadler, Stephen
Wang, Xiaojun
Luo, Huiming
Chen, Yuansheng
Kane, Mark
Shapiro, Craig
Yang, Weizhong
Wang, Yu
TI Origins, design and implementation of the China GAVI project
SO VACCINE
LA English
DT Review
DE Hepatitis B; Vaccine; Project
ID HEPATITIS-B-VIRUS; VACCINATION
AB China received GAVI support for hepatitis B vaccination in 2001 because of high disease burden and strong government will to protect infants at risk. The China/GAVI project, implemented since 2002, was funded 50% by GAVI and 50% by the Government of China. The purpose of the project was to increase coverage of hepatitis B vaccine through a pro-poor approach targeting all counties of the 12 Western provinces and poverty counties of the 10 Central provinces, to accelerate integration of hepatitis B vaccine into routine immunization, and assure immunization injection safety. The mechanism of internal coordination among multiple government entities and international cooperation was established and comprehensive strategies were used to improve vaccine coverage and injection safety. After 8 years of implementation, 193,000 health care workers in 118,316 health care facilities participated in the project, mostly at the township hospitals level (55,051) and in community centres (104,547). Through the China GAVI project, the 85% HepB3 coverage goal was reached in 98% of GAVI China project counties, the 75% timely birth dose (TBD) coverage goal was reached in 80% of GAVI project counties, and AD syringes were introduced into 100% of GAVI-supported areas. Additionally, the GAVI project was instrumental in convincing the Chinese Government to sustainably introduce and fully fund HepB vaccine for all newborns in China. The impact of hepB vaccination on HBsAg prevalence was observed throughout China, as HBsAg prevalence (previously similar to 10%) is now less than 1% among children under 5 years of age. (C) 2012 Elsevier Ltd. All rights reserved.
C1 [Liang, Xiaofeng; Cui, Fuqiang; Luo, Huiming; Chen, Yuansheng; Yang, Weizhong; Wang, Yu] Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China.
[Hadler, Stephen; Shapiro, Craig] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Kane, Mark] WHO, Western Pacific Reg Off, Manila, Philippines.
RP Wang, Y (reprint author), Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China.
EM Wangyu@chinacdc.cn
NR 16
TC 7
Z9 7
U1 3
U2 9
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 27
PY 2013
VL 31
SU 9
BP J8
EP J14
DI 10.1016/j.vaccine.2012.12.019
PG 7
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 289MA
UT WOS:000329685400005
PM 24331025
ER
PT J
AU Wu, ZH
Cui, FQ
Chen, YS
Miao, N
Gong, XH
Luo, HM
Wang, FZ
Zheng, H
Kane, M
Hadler, SC
Hutin, YJ
Liang, XF
Yang, WZ
AF Wu, Zhenhua
Cui, Fuqiang
Chen, Yuansheng
Miao, Ning
Gong, Xiaohong
Luo, Huiming
Wang, Fuzhen
Zheng, Hui
Kane, Mark
Hadler, Stephen C.
Hutin, Yvan J.
Liang, Xiaofeng
Yang, Weizhong
TI Evaluation of immunization injection safety in China, 2010:
Achievements, future sustainability
SO VACCINE
LA English
DT Article
DE Immunization; Injection safety; Evaluation
ID UNITED-STATES; HEPATITIS-B
AB Objective: The study objectives were to evaluate injection practices in China in the post GAVI project era and provide guidance for policy makers to update national standards for injection practices and further improve vaccination services.
Methods: We conducted a national stratified, cross-sectional survey in October 2010, according to WHO recommended sampling methods. First, we stratified China into three regions (Eastern, Central and Western) based on economic criteria. Second, in each region, we selected eight counties with a probability proportional to population size. Third, in each selected county, we selected (a) 10 townships at random among the list of townships of the county and (b) the one county level hospital.
Results: With respect to the risk to the patient, we never observed open injection equipment lying around or needles left in the septum of multi-dose vials. We never observed sterilizable injection devices syringes in any of the facilities. The proportion of facilities using sharps containers was highest in the East (85%), intermediate in the West (79%) and lowest in the Central region (56%). In 2009, auto-disable syringes and safety boxes were used in 78% and 79% facilities in GAVI supported areas of the Western region, respectively. Only one facility presented evidence of attempts to re-sterilize disposable injection equipment in the Eastern region.
Conclusions: Use of AD syringe and sharps containers increased in vaccination services in China, especially in GAVI supported areas, leading to sustainable progress in terms of elimination of reuse of injection devices. However, risk to patients still existed, including persisting use of standard disposable syringes and attempts to re-use disposable devices. (C) 2012 Elsevier Ltd. All rights reserved.
C1 [Wu, Zhenhua; Cui, Fuqiang; Chen, Yuansheng; Miao, Ning; Gong, Xiaohong; Luo, Huiming; Wang, Fuzhen; Zheng, Hui; Liang, Xiaofeng; Yang, Weizhong] Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China.
[Hadler, Stephen C.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Hutin, Yvan J.] World Hlth Org Off China, Beijing, Peoples R China.
RP Cui, FQ (reprint author), Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China.
EM Cuifuq@126.com
NR 17
TC 2
Z9 2
U1 1
U2 4
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 27
PY 2013
VL 31
SU 9
BP J43
EP J48
DI 10.1016/j.vaccine.2012.11.057
PG 6
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 289MA
UT WOS:000329685400010
PM 24331020
ER
PT J
AU Yang, WZ
Liang, XF
Cui, FQ
Li, L
Hadler, SC
Hutin, YJ
Kane, M
Wang, Y
AF Yang, Weizhong
Liang, Xiaofeng
Cui, Fuqiang
Li, Li
Hadler, Stephen C.
Hutin, Yvan J.
Kane, Mark
Wang, Yu
TI Key outcomes and addressing remaining challenges-Perspectives from a
final evaluation of the China GAVI project
SO VACCINE
LA English
DT Article
DE GAVI; Project; Outcomes; Challenges
ID HEALTH-CARE WORKERS; HEPATITIS-B; JAPANESE ENCEPHALITIS;
COST-EFFECTIVENESS; IMMUNIZATION; VACCINATION; INJURIES; PROGRAM; BURDEN
AB During the China GAVI project, implemented between 2002 and 2010, more than 25 million children received hepatitis B vaccine with the support of project, and the vaccine proved to be safe and effective. With careful consideration for project savings, China and GAVI continually adjusted the budget, additionally allowing the project to spend operational funds to support demonstration projects to improve timely birth dose (TBD), conduct training of EPI staff, and to monitor the project impact. Results from the final evaluation indicated the achievement of key outcomes. As a result of government co-investment, human resources at county level engaged in hepatitis B vaccination increased from 29 per county on average in 2002 to 66 in 2009. All project counties funded by the GAVI project use auto-disable syringes for hepatitis B vaccination and other vaccines. Surveyed hepatitis B vaccine coverage increased from 71% in 2002 to 93% in 2009 among infants. The HBsAg prevalence declined from 9.67% in 1992 to 0.96% in 2006 among children under 5 years of age. However, several important issues remain: (1) China still accounts for the largest annual number of perinatal HBV infections (estimated 84,121) in the WHO WPR region; (2) China still lacks a clear national policy for safe injection of vaccines; (3) vaccination of high risk adults and protection of health care workers are still not implemented; (4) hepatitis B surveillance needs to be refined to more accurately monitor acute hepatitis B; and (5) a program for treatment of persons with chronic HBV infection is needed. Recommendations for future hepatitis B control include: using the lessons learned from the China GAVI project for future introductions of new vaccines; addressing unmet needs with a second generation hepatitis B program to reach every infant, including screening mothers, and providing HBIG for infants born to HBsAg positive mothers; expanding vaccination to high risk adults; addressing remaining unsafe injection issues; and improving monitoring of acute hepatitis B. This paper describes findings and discusses perspectives from a final project evaluation, a national stratified validated cross-sectional survey done in October 2010. (C) 2012 Elsevier Ltd. All rights reserved.
C1 [Yang, Weizhong; Liang, Xiaofeng; Cui, Fuqiang; Li, Li; Wang, Yu] Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China.
[Hadler, Stephen C.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Hutin, Yvan J.] Europe Ctr Dis Control & Prevent, Stockholm, Sweden.
RP Wang, Y (reprint author), Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China.
EM Wangyu@chinacdc.cn
NR 30
TC 2
Z9 2
U1 2
U2 6
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 27
PY 2013
VL 31
SU 9
BP J73
EP J78
DI 10.1016/j.vaccine.2012.09.060
PG 6
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 289MA
UT WOS:000329685400015
PM 24331024
ER
PT J
AU Roberge, RJ
Kim, JH
Powell, JB
Shaffer, RE
Ylitalo, CM
Sebastian, JM
AF Roberge, Raymond J.
Kim, Jung-Hyun
Powell, Jeffrey B.
Shaffer, Ronald E.
Ylitalo, Caroline M.
Sebastian, John M.
TI Impact of Low Filter Resistances on Subjective and Physiological
Responses to Filtering Facepiece Respirators
SO PLOS ONE
LA English
DT Article
ID HEALTH-CARE WORKERS; BREATHING RESISTANCE; CARBON-DIOXIDE; N95;
PERCEPTION; LOADS; APPARATUS; HUMIDITY; DEVICES; HUMANS
AB Ten subjects underwent treadmill exercise at 5.6 km/h over one hour while wearing each of three identical appearing, cup-shaped, prototype filtering facepiece respirators that differed only in their filter resistances (3 mm, 6 mm, and 9 mm H2O pressure drop). There were no statistically significant differences between filtering facepiece respirators with respect to impact on physiological parameters (i.e., heart rate, respiratory rate, oxygen saturation, transcutaneous carbon dioxide levels, tympanic membrane temperature), pulmonary function variables (i.e., tidal volume, respiratory rate, volume of carbon dioxide production, oxygen consumption, or ventilation), and subjective ratings (i.e., exertion, thermal comfort, inspiratory effort, expiratory effort and overall breathing comfort). The nominal filter resistances of the prototype filtering facepiece respirators correspond to airflow resistances ranging from 2.1 - 6.6 mm H2O/L/s which are less than, or minimally equivalent to, previously reported values for the normal threshold for detection of inspiratory breathing resistance (6 - 7.6 mm H2O/L/sec). Therefore, filtering facepiece respirators with filter resistances at, or below, this level may not impact the wearer differently physiologically or subjectively from those with filter resistances only slightly above this threshold at low-moderate work rates over one hour.
C1 [Roberge, Raymond J.; Kim, Jung-Hyun; Powell, Jeffrey B.; Shaffer, Ronald E.] NIOSH, Technol Res Branch, Natl Personal Protect Technol Lab, Ctr Dis Control & Prevent, Pittsburgh, PA 15236 USA.
[Ylitalo, Caroline M.; Sebastian, John M.] 3M Co, Personal Safety Div, St Paul, MN 55144 USA.
RP Roberge, RJ (reprint author), NIOSH, Technol Res Branch, Natl Personal Protect Technol Lab, Ctr Dis Control & Prevent, Pittsburgh, PA 15236 USA.
EM dtn0@cdc.gov
FU National Institute for Occupational Safety and Health (NIOSH); US
Centers for Disease Control and Prevention
FX This work was supported by internal operating funds from the National
Institute for Occupational Safety and Health (NIOSH), part of the US
Centers for Disease Control and Prevention. Raymond J. Roberge,
Jung-Hyun Kim, Jeffrey B. Powell, and Ronald E. Shaffer are NIOSH
employees who were involved in conducting the study, analyzing the
results, and preparing the manuscript.
NR 44
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U1 1
U2 9
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 27
PY 2013
VL 8
IS 12
AR e84901
DI 10.1371/journal.pone.0084901
PG 7
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 281RE
UT WOS:000329117900117
PM 24386434
ER
PT J
AU Rey, GU
Miao, CR
Caidi, H
Trivedi, SU
Harcourt, JL
Tripp, RA
Anderson, LJ
Haynes, LM
AF Rey, Gertrud U.
Miao, Congrong
Caidi, Hayat
Trivedi, Suvang U.
Harcourt, Jennifer L.
Tripp, Ralph A.
Anderson, Larry J.
Haynes, Lia M.
TI Decrease in Formalin-Inactivated Respiratory Syncytial Virus (FI-RSV)
Enhanced Disease with RSV G Glycoprotein Peptide Immunization in BALB/c
Mice
SO PLOS ONE
LA English
DT Article
ID PULMONARY INFLAMMATORY RESPONSE; MESSENGER-RNA EXPRESSION; ATTACHMENT G
PROTEIN; SUBSTANCE-P; YOUNG-CHILDREN; T-CELLS; VACCINE; INFECTION;
EOSINOPHILIA; IMMUNOGENICITY
AB Respiratory syncytial virus (RSV) is a high priority target for vaccine development. One concern in RSV vaccine development is that a non-live virus vaccine would predispose for enhanced disease similar to that seen with the formalin inactivated RSV (FI-RSV) vaccine. Since a mAb specific to RSV G protein can reduce pulmonary inflammation and eosinophilia seen after RSV infection of FI-RSV vaccinated mice, we hypothesized that RSV G peptides that induce antibodies with similar reactivity may limit enhanced disease after subunit or other non-live RSV vaccines. In support of this hypothesis, we show that FI-RSV vaccinated mice administered RSV G peptide vaccines had a significant reduction in enhanced disease after RSV challenge. These data support the importance of RSV G during infection to RSV disease pathogenesis and suggest that use of appropriately designed G peptide vaccines to reduce the risk of enhanced disease with non-live RSV vaccines merits further study.
C1 [Rey, Gertrud U.; Miao, Congrong; Caidi, Hayat; Trivedi, Suvang U.; Harcourt, Jennifer L.; Haynes, Lia M.] Ctr Dis Control & Prevent CDC, Natl Ctr Immunizat & Resp Dis, Div Viral Dis, Gastroenteritis & Resp Viruses Lab Branch, Atlanta, GA 30333 USA.
[Tripp, Ralph A.] Univ Georgia, Coll Vet Med, Dept Infect Dis, Athens, GA USA.
[Anderson, Larry J.] Emory Univ, Dept Pediat, Atlanta, GA 30322 USA.
[Anderson, Larry J.] Childrens Healthcare Atlanta, Emory Childrens Ctr, Atlanta, GA USA.
RP Haynes, LM (reprint author), Ctr Dis Control & Prevent CDC, Natl Ctr Immunizat & Resp Dis, Div Viral Dis, Gastroenteritis & Resp Viruses Lab Branch, Atlanta, GA 30333 USA.
EM loh5@cdc.gov
OI Tripp, Ralph/0000-0002-2924-9956
FU appointment to the Research Participation Program at the Centers for
Disease Control and Prevention (CDC); National Institutes of Health
[5RO1AI06275-03]; Georgia Research Alliance
FX This research was supported in part by an appointment to the Research
Participation Program at the Centers for Disease Control and Prevention
(CDC) administered by the Oak Ridge Institute for Science and Education
(ORISE) through an interagency agreement between the U.S. Department of
Energy and CDC. G. R. and SUT were ORISE Fellows at the time this study
was performed. This research was also supported in part by the National
Institutes of Health (5RO1AI06275-03) and through the Georgia Research
Alliance to R. T. The funders had no role in study design, data
collection and analysis, decision to publish, or preparation of the
manuscript.
NR 43
TC 2
Z9 2
U1 0
U2 2
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 23
PY 2013
VL 8
IS 12
AR e83075
DI 10.1371/journal.pone.0083075
PG 13
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 278IG
UT WOS:000328882000056
PM 24376637
ER
PT J
AU Yuen, CM
Kurbatova, EV
Click, ES
Cavanaugh, JS
Cegielski, JP
AF Yuen, Courtney M.
Kurbatova, Ekaterina V.
Click, Eleanor S.
Cavanaugh, J. Sean
Cegielski, J. Peter
TI Association between Mycobacterium tuberculosis Complex Phylogenetic
Lineage and Acquired Drug Resistance
SO PLOS ONE
LA English
DT Article
ID SHORT-COURSE CHEMOTHERAPY; UNITED-STATES; PYRAZINAMIDE; SUSCEPTIBILITY;
RELAPSE; METAANALYSIS; GENOTYPE; MUTATION; OUTCOMES; BOVIS
AB Background: Development of resistance to antituberculosis drugs during treatment (i.e., acquired resistance) can lead to emergence of resistant strains and consequent poor clinical outcomes. However, it is unknown whether Mycobacterium tuberculosis complex species and lineage affects the likelihood of acquired resistance.
Methods: We analyzed data from the U. S. National Tuberculosis Surveillance System and National Tuberculosis Genotyping Service for tuberculosis cases during 2004-2011 with assigned species and lineage and both initial and final drug susceptibility test results. We determined univariate associations between species and lineage of Mycobacterium tuberculosis complex bacteria and acquired resistance to isoniazid, rifamycins, fluoroquinolones, and second-line injectables. We used Poisson regression with backward elimination to generate multivariable models for acquired resistance to isoniazid and rifamycins.
Results: M. bovis was independently associated with acquired resistance to isoniazid (adjusted prevalence ratio = 8.46, 95% CI 2.96-24.14) adjusting for HIV status, and with acquired resistance to rifamycins (adjusted prevalence ratio = 4.53, 95% CI 1.29-15.90) adjusting for homelessness, HIV status, initial resistance to isoniazid, site of disease, and administration of therapy. East Asian lineage was associated with acquired resistance to fluoroquinolones (prevalence ratio = 6.10, 95% CI 1.56-23.83).
Conclusions: We found an association between mycobacterial species and lineage and acquired drug resistance using U. S. surveillance data. Prospective clinical studies are needed to determine the clinical significance of these findings, including whether rapid genotyping of isolates at the outset of treatment may benefit patient management.
C1 [Yuen, Courtney M.; Kurbatova, Ekaterina V.; Click, Eleanor S.; Cavanaugh, J. Sean; Cegielski, J. Peter] US Ctr Dis Control & Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Div TB Eliminat, Atlanta, GA 30333 USA.
RP Kurbatova, EV (reprint author), US Ctr Dis Control & Prevent, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Div TB Eliminat, Atlanta, GA 30333 USA.
EM EKurbatova@cdc.gov
NR 37
TC 4
Z9 4
U1 0
U2 2
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 23
PY 2013
VL 8
IS 12
AR e83006
DI 10.1371/journal.pone.0083006
PG 9
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 278IG
UT WOS:000328882000050
PM 24376623
ER
PT J
AU Abdulla, S
Alonso, P
Binka, F
Graves, P
Greenwood, B
Leke, R
Malik, E
Marsh, K
Meek, S
Mendis, K
Schapira, A
Slutsker, L
Tanner, M
Valecha, N
White, N
Bosman, A
Cibulskis, R
D'Souza, B
Lynch, M
MacDonald, M
Mintcheva, R
Mnzava, A
Newman, R
Ringwald, P
Szilagyi, Z
Wongsrichanalai, C
AF Abdulla, Salim
Alonso, Pedro
Binka, Fred
Graves, Patricia
Greenwood, Brian
Leke, Rose
Malik, Elfatih
Marsh, Kevin
Meek, Sylvia
Mendis, Kamini
Schapira, Allan
Slutsker, Laurence
Tanner, Marcel
Valecha, Neena
White, Nicholas
Bosman, Andrea
Cibulskis, Richard
D'Souza, Bianca
Lynch, Michael
MacDonald, Michael
Mintcheva, Rossitza
Mnzava, Abraham
Newman, Robert
Ringwald, Pascal
Szilagyi, Zsofia
Wongsrichanalai, Chansuda
CA WHO Malaria Policy Advisory Comm
TI Malaria Policy Advisory Committee to the WHO: conclusions and
recommendations of September 2013 meeting
SO MALARIA JOURNAL
LA English
DT Article
DE WHO; Malaria; Policy making; Mosquito control; Pregnancy; Prevention;
Sulphadoxine-pyrimethamine; Treatment efficacy; Drug resistance;
Surveillance; Elimination; Plasmodium falciparum; Plasmodium vivax
AB The Malaria Policy Advisory Committee to the World Health Organization held its fourth meeting in Geneva, Switzerland from 11 to 13 September, 2013. This article provides a summary of the discussions, conclusions and recommendations from that meeting.
Meeting sessions included: recommendations for achieving universal coverage of long-lasting insecticide-treated nets; guidance on estimating the longevity of insecticide-treated nets; improving capacity in entomology and vector control; a review of the latest evidence on intermittent preventive treatment in pregnancy; improving dissemination of Malaria Policy Advisory Committee guidance; updates on the development of the global technical strategy for malaria control and elimination (2016-2025) and the global strategy for control and elimination of Plasmodium vivax; updates from the drug resistance and containment technical expert group, the evidence review group on malaria burden estimation, a consultation on malaria case management indicators, and the constitution of the surveillance, monitoring and evaluation technical expert group; subnational elimination criteria; and consideration for future evidence review groups, including diagnosis in low transmission settings and testing for Glucose-6-Phosphate Dehydrogenase Deficiency.
Policy statements, position statements and guidelines that arise from the Malaria Policy Advisory Committee meeting conclusions and recommendations will be formally issued and disseminated to World Health Organization Member States by the World Health Organization Global Malaria Programme.
C1 [Abdulla, Salim] Ifakara Hlth Inst, Dar Es Salaam, Tanzania.
[Alonso, Pedro] Ctr Int Hlth & Res, Barcelona, Spain.
[Binka, Fred] Univ Ghana, Accra, Ghana.
[Graves, Patricia] James Cook Univ, Cairns, Australia.
[Greenwood, Brian; D'Souza, Bianca] London Sch Hyg & Trop Med, London WC1, England.
[Leke, Rose] Univ Yaounde, Yaounde, Cameroon.
[Malik, Elfatih] Minist Hlth, Gezira, Sudan.
[Marsh, Kevin] Kenya Govt Med Res Ctr, Kilifi, Kenya.
[Meek, Sylvia] Malaria Consortium, London, England.
[Slutsker, Laurence] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Tanner, Marcel] Swiss Trop Publ Hlth Inst, Basel, Switzerland.
[Valecha, Neena] Natl Inst Malaria Res, New Delhi, India.
[White, Nicholas] Mahidol Univ, Bangkok 10700, Thailand.
[Bosman, Andrea; Cibulskis, Richard; D'Souza, Bianca; MacDonald, Michael; Mintcheva, Rossitza; Mnzava, Abraham; Newman, Robert; Ringwald, Pascal; Szilagyi, Zsofia; Wongsrichanalai, Chansuda] WHO Global Malaria Programme, Geneva, Switzerland.
RP Abdulla, S (reprint author), WHO, Global Malaria Programme, 20 Ave Appia 27, CH-1211 Geneva, Switzerland.
EM mpacgmp@who.int
RI Graves, Patricia/J-8691-2014
OI Graves, Patricia/0000-0002-5215-3901
FU Bill & Melinda Gates Foundation; UK Department for International
Development (DFID); United States Agency for International Development
(USAID)
FX The authors gratefully acknowledge the hard work of the many people who
contributed to the background documents and other preparations for the
MPAC meeting: WHO-GMP staff, in particular Kathryn Andrews, Jane
Cunningham, and Lise Riopel; Peter Smith (Chair, ERG MBE) from the
London School of Hygiene and Tropical Medicine; and Melanie Renshaw
(Chair, VC TEG) from the African Leaders Malaria Alliance. The authors
also thank all the MPAC meeting participants and observers for their
contributions during the meeting discussions. The MPAC process is
supported in part by grants from the Bill & Melinda Gates Foundation,
the UK Department for International Development (DFID), and the United
States Agency for International Development (USAID) to the WHO Global
Malaria Programme.
NR 44
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U2 13
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1475-2875
J9 MALARIA J
JI Malar. J.
PD DEC 20
PY 2013
VL 12
AR 456
DI 10.1186/1475-2875-12-456
PG 12
WC Infectious Diseases; Parasitology; Tropical Medicine
SC Infectious Diseases; Parasitology; Tropical Medicine
GA 297HT
UT WOS:000330247200001
ER
PT J
AU Schillie, S
Murphy, TV
Sawyer, M
Ly, K
Hughes, E
Jiles, R
de Perio, MA
Reilly, M
Byrd, K
Ward, JW
AF Schillie, Sarah
Murphy, Trudy V.
Sawyer, Mark
Ly, Kathleen
Hughes, Elizabeth
Jiles, Ruth
de Perio, Marie A.
Reilly, Meredith
Byrd, Kathy
Ward, John W.
TI CDC Guidance for Evaluating Health-Care Personnel for Hepatitis B Virus
Protection and for Administering Postexposure Management
SO MMWR RECOMMENDATIONS AND REPORTS
LA English
DT Article
ID DIALYSIS-ASSOCIATED HEPATITIS; IMMUNE SERUM GLOBULIN; UNITED-STATES;
VACCINATION COVERAGE; REGISTERED NURSES; VIRAL-HEPATITIS; FINAL REPORT;
CONTROLLED TRIAL; BLOOD EXPOSURE; DOUBLE-BLIND
AB This report contains CDC guidance that augments the 2011 recommendations of the Advisory Committee on Immunization Practices (ACIP) for evaluating hepatitis B protection among health-care personnel (HCP) and administering post-exposure prophylaxis. Explicit guidance is provided for persons working, training, or volunteering in health-care settings who have documented hepatitis B (HepB) vaccination years before hire or matriculation (e. g., when HepB vaccination was received as part of routine infant [recommended since 1991] or catch-up adolescent [recommended since 1995] vaccination).
In the United States, 2,890 cases of acute hepatitis B were reported to CDC in 2011, and an estimated 18,800 new cases of hepatitis B occurred after accounting for underreporting of cases and asymptomatic infection. Although the rate of acute hepatitis B virus (HBV) infections have declined approximately 89% during 1990-2011, from 8.5 to 0.9 cases per 100,000 population in the United States, the risk for occupationally acquired HBV among HCP persists, largely from exposures to patients with chronic HBV infection.
ACIP recommends HepB vaccination for unvaccinated or incompletely vaccinated HCP with reasonably anticipated risk for blood or body fluid exposure. ACIP also recommends that vaccinated HCP receive postvaccination serologic testing (antibody to hepatitis B surface antigen [anti-HBs]) 1-2 months after the final dose of vaccine is administered (CDC. Immunization of health-care personnel: recommendations of the Advisory Committee on Immunization Practices [ACIP]. MMWR 2011;60 [No. RR-7]). Increasing numbers of HCP have received routine HepB vaccination either as infants (recommended since 1991) or as catch-up vaccination (recommended since 1995) in adolescence. HepB vaccination results in protective anti-HBs responses among approximately 95% of healthy-term infants. Certain institutions test vaccinated HCP by measuring anti-HBs upon hire or matriculation, even when anti-HBs testing occurs greater than 2 months after vaccination. This guidance can assist clinicians, occupational health and student health providers, infection-control specialists, hospital and health-care training program administrators, and others in selection of an approach for assessing HBV protection for vaccinated HCP. This report emphasizes the importance of administering HepB vaccination for all HCP, provides explicit guidance for evaluating hepatitis B protection among previously vaccinated HCP (particularly those who were vaccinated in infancy or adolescence), and clarifies recommendations for postexposure management of HCP exposed to blood or body fluids.
C1 [Sawyer, Mark] Univ Calif San Diego, San Diego, CA 92103 USA.
[de Perio, Marie A.] NIOSH, CDC, Washington, DC 20201 USA.
[Reilly, Meredith] Johns Hopkins Univ, Sch Publ Hlth, Baltimore, MD 21218 USA.
EM sschillie@cdc.gov
RI Nace, David/D-2638-2014
FU Merck; Sanofi; Pfizer pharmaceutical companies; MedImmune
FX The developers of these guidelines wish to disclose that they have no
financial interests or other relationships with the manufacturers of
commercial products or suppliers of commercial services related to
vaccines including any related to hepatitis B vaccines, with the
following exceptions: David Weber, MD, wishes to disclose that he served
as a consultant and on a speakers' bureau, whether paid or unpaid (e.g.,
travel related reimbursement, honoraria), for the following vaccine
manufacturers: Merck, Sanofi, and Pfizer pharmaceutical companies. Amy
B. Middleman, MD, also wishes to disclose that she received grant
funding from the following pharmaceutical companies: MedImmune, Sanofi,
and Merck.
NR 89
TC 30
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U1 0
U2 4
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 1057-5987
EI 1545-8601
J9 MMWR RECOMM REP
JI MMWR Recomm. Rep.
PD DEC 20
PY 2013
VL 62
IS 10
BP 1
EP 19
PG 19
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 290KL
UT WOS:000329755000001
PM 24352112
ER
PT J
AU Carriquiry, A
Moshfegh, AJ
Steinfeldt, LC
Cogswell, ME
Loustalot, F
Zhang, ZF
Yang, QH
Tian, N
AF Carriquiry, Alicia
Moshfegh, Alanna J.
Steinfeldt, Lois C.
Cogswell, Mary E.
Loustalot, Fleetwood
Zhang, Zefeng
Yang, Quanhe
Tian, Niu
TI Trends in the Prevalence of Excess Dietary Sodium Intake - United
States, 2003-2010
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Article
ID CONSUMPTION
C1 [Carriquiry, Alicia] Iowa State Univ, Ames, IA 50011 USA.
[Tian, Niu] CDC, Atlanta, GA 30333 USA.
RP Tian, N (reprint author), CDC, Atlanta, GA 30333 USA.
EM vii9@cdc.gov
NR 9
TC 20
Z9 20
U1 0
U2 4
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 20
PY 2013
VL 62
IS 50
BP 1021
EP 1025
PG 5
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 278AX
UT WOS:000328861500001
ER
PT J
AU Teague, NS
Grigg, SS
Peterson, JC
Gomez, GA
Talkington, DF
AF Teague, Nathan S.
Grigg, Stephanie S.
Peterson, Jasmine C.
Gomez, Gerardo A.
Talkington, Deborah F.
TI Outbreak of Staphylococcal Food Poisoning from a Military Unit Lunch
Party - United States, July 2012
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Article
ID AUREUS
C1 [Gomez, Gerardo A.; Talkington, Deborah F.] CDC, Div Foodborne Waterborne & Environm Dis, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA.
EM nathaniel.teague@afrims.org; goe4@cdc.gov
NR 7
TC 2
Z9 2
U1 0
U2 3
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 20
PY 2013
VL 62
IS 50
BP 1026
EP 1028
PG 3
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 278AX
UT WOS:000328861500002
ER
PT J
AU Foley, C
Harvey, E
Bidol, SA
Henderson, T
Njord, R
DeSalvo, T
Haupt, T
Mba-Jonas, A
Bailey, C
Bopp, C
Bosch, SA
Gerner-Smidt, P
Mody, RK
Nguyen, TA
Strockbine, N
Tauxe, RV
AF Foley, Catherine
Harvey, Emily
Bidol, Sally A.
Henderson, Tiffany
Njord, Rebecca
DeSalvo, Traci
Haupt, Thomas
Mba-Jonas, Adamma
Bailey, Chris
Bopp, Cheryl
Bosch, Stacey A.
Gerner-Smidt, Peter
Mody, Rajal K.
Thai-An Nguyen
Strockbine, Nancy
Tauxe, Robert V.
TI Outbreak of Escherichia coli O104:H4 Infections Associated with Sprout
Consumption - Europe and North America, May-July 2011
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Article
C1 [Harvey, Emily] Massachusetts Dept Publ Hlth, Boston, MA 02111 USA.
[Mba-Jonas, Adamma] US FDA, Dept Epidemiol, Ctr Biol Evaluat & Res, Rockville, MD 20857 USA.
[Bailey, Chris; Bopp, Cheryl; Bosch, Stacey A.; Gerner-Smidt, Peter; Mody, Rajal K.; Thai-An Nguyen; Strockbine, Nancy; Tauxe, Robert V.] CDC, Div Foodborne Waterborne & Environm Dis, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA.
RP Mba-Jonas, A (reprint author), US FDA, Dept Epidemiol, Ctr Biol Evaluat & Res, Rockville, MD 20857 USA.
EM adamma.mba-jonas@fda.hhs.gov
NR 10
TC 11
Z9 11
U1 0
U2 5
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 20
PY 2013
VL 62
IS 50
BP 1029
EP 1031
PG 3
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 278AX
UT WOS:000328861500003
ER
PT J
AU Brammer, L
Epperson, S
Blanton, L
Kniss, K
Mustaquim, D
Steffens, C
Dhara, R
Leon, M
Perez, A
Chaves, S
Katz, J
Wallis, T
Villanueva, J
Xu, XY
Elal, AIA
Gubareva, L
Finelli, L
Bresee, J
Cox, N
Millman, A
AF Brammer, Lynnette
Epperson, Scott
Blanton, Lenee
Kniss, Krista
Mustaquim, Desiree
Steffens, Craig
Dhara, Rosaline
Leon, Michelle
Perez, Alejandro
Chaves, Sandra
Katz, Jackie
Wallis, Teresa
Villanueva, Julie
Xu, Xiyan
Elal, Anwar Isa Abd
Gubareva, Larisa
Finelli, Lyn
Bresee, Joseph
Cox, Nancy
Millman, Alexander
TI Update: Influenza Activity - United States, September 29-December 7,
2013
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Article
RP Millman, A (reprint author), CDC, Atlanta, GA 30333 USA.
EM amillman@cdc.gov
NR 5
TC 3
Z9 3
U1 0
U2 0
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 20
PY 2013
VL 62
IS 50
BP 1032
EP 1036
PG 5
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 278AX
UT WOS:000328861500004
ER
PT J
AU Painter, JA
Graviss, EA
Hai, HH
Nhung, DTC
Nga, TTT
Ha, NP
Wall, K
Loan, LTH
Parker, M
Manangan, L
O'Brien, R
Maloney, SA
Hoekstra, RM
Reves, R
AF Painter, John A.
Graviss, Edward A.
Hoang Hoa Hai
Duong Thi Cam Nhung
Tran Thi Thanh Nga
Ha, Ngan P.
Wall, Kirsten
Le Thien Huong Loan
Parker, Matt
Manangan, Lilia
O'Brien, Rick
Maloney, Susan A.
Hoekstra, R. M.
Reves, Randall
TI Tuberculosis Screening by Tuberculosis Skin Test or QuantiFERON (R)-TB
Gold In-Tube Assay among an Immigrant Population with a High Prevalence
of Tuberculosis and BCG Vaccination
SO PLOS ONE
LA English
DT Article
ID GAMMA RELEASE ASSAYS; FOREIGN-BORN PERSONS; UNITED-STATES; INFECTION;
DIAGNOSIS; METAANALYSIS; TB; ELIMINATION
AB Rationale: Each year 1 million persons acquire permanent U. S. residency visas after tuberculosis (TB) screening. Most applicants undergo a 2-stage screening with tuberculin skin test (TST) followed by CXR only if TST-positive at > 5 mm. Due to cross reaction with bacillus Calmette-Guerin (BCG), TST may yield false positive results in BCG-vaccinated persons. Interferon gamma release assays exclude antigens found in BCG. In Vietnam, like most high TB-prevalence countries, there is universal BCG vaccination at birth.
Objectives: 1. Compare the sensitivity of QuantiFERON (R)-TB Gold In-Tube Assay (QFT) and TST for culture-positive pulmonary TB. 2. Compare the age-specific and overall prevalence of positive TST and QFT among applicants with normal and abnormal CXR.
Methods: We obtained TST and QFT results on 996 applicants with abnormal CXR, of whom 132 had TB, and 479 with normal CXR.
Results: The sensitivity for tuberculosis was 86.4% for QFT; 89.4%, 81.1%, and 52.3% for TST at 5, 10, and 15 mm. The estimated prevalence of positive results at age 15-19 years was 22% and 42% for QFT and TST at 10 mm, respectively. The prevalence increased thereafter by 0.7% year of age for TST and 2.1% for QFT, the latter being more consistent with the increase in TB among applicants.
Conclusions: During 2-stage screening, QFT is as sensitive as TST in detecting TB with fewer requiring CXR and being diagnosed with LTBI. These data support the use of QFT over TST in this population.
C1 [Painter, John A.] Ctr Dis Control & Prevent, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA.
[Graviss, Edward A.; Ha, Ngan P.] Methodist Hosp Res Inst, Houston, TX USA.
[Hoang Hoa Hai; Duong Thi Cam Nhung; Tran Thi Thanh Nga; Le Thien Huong Loan] Cho Ray Hosp, Visa Med Unit, Ho Chi Minh City, Vietnam.
[Wall, Kirsten; Parker, Matt; Reves, Randall] Denver Hlth & Hosp Author, Denver, CO USA.
[Manangan, Lilia] Ctr Dis Control & Prevent, Natl Ctr HIV Hepatitis STD & TB Prevent, Atlanta, GA USA.
[O'Brien, Rick] Fdn Innovat New Diagnost, Geneva, Switzerland.
[Maloney, Susan A.] Ctr Dis Control & Prevent, Ctr Global Hlth, Atlanta, GA USA.
[Hoekstra, R. M.] Ctr Dis Control & Prevent, Biostat & Informat Management Off, Div Foodborne Waterborne & Environm Dis, Atlanta, GA USA.
RP Painter, JA (reprint author), Ctr Dis Control & Prevent, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA.
EM jpainter@cdc.gov
FU Tuberculosis Epidemiologic Studies Consortium (TBESC) of the United
States Centers for the Disease Control and Prevention
FX Funding for the study was achieved through the Tuberculosis
Epidemiologic Studies Consortium (TBESC) of the United States Centers
for the Disease Control and Prevention. QuantiFERON (R)-TB Gold In-Tube
Assay kits were provided by the Foundation for Innovative New
Diagnostics. The funders had no role in study design, data collection
and analysis, decision to publish, or preparation of the manuscript.
NR 37
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U1 0
U2 1
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 19
PY 2013
VL 8
IS 12
AR UNSP e82727
DI 10.1371/journal.pone.0082727
PG 9
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 276HY
UT WOS:000328741900012
PM 24367546
ER
PT J
AU Niederkrotenthaler, T
Parker, EM
Ovalle, F
Noe, RE
Bell, J
Xu, LK
Morrison, MA
Mertzlufft, CE
Sugerman, DE
AF Niederkrotenthaler, Thomas
Parker, Erin M.
Ovalle, Fernando
Noe, Rebecca E.
Bell, Jeneita
Xu, Likang
Morrison, Melissa A.
Mertzlufft, Caitlin E.
Sugerman, David E.
TI Injuries and Post-Traumatic Stress following Historic Tornados: Alabama,
April 2011
SO PLOS ONE
LA English
DT Article
ID RISK-FACTORS; DISASTER PREPAREDNESS; NATURAL DISASTER; DISORDER;
OKLAHOMA; DEATH; BANGLADESH; ILLINOIS; GEORGIA; SYSTEM
AB Objectives: We analyzed tornado-related injuries seen at hospitals and risk factors for tornado injury, and screened for post-traumatic stress following a statewide tornado-emergency in Alabama in April 2011.
Methods: We conducted a chart abstraction of 1,398 patients at 39 hospitals, mapped injured cases, and conducted a case-control telephone survey of 98 injured cases along with 200 uninjured controls.
Results: Most (n = 1,111, 79.5%) injuries treated were non-life threatening (Injury Severity Score <= 15). Severe injuries often affected head (72.9%) and chest regions (86.4%). Mobile home residents showed the highest odds of injury (OR, 6.98; 95% CI: 2.10-23.20). No severe injuries occurred in tornado shelters. Within permanent homes, the odds of injury were decreased for basements (OR, 0.13; 95% CI: 0.04-0.40), bathrooms (OR, 0.22; 95% CI: 0.06-0.78), hallways (OR, 0.31; 95% CI: 0.11-0.90) and closets (OR, 0.25; 95% CI: 0.07-0.80). Exposure to warnings via the Internet (aOR, 0.20; 95% CI: 0.09-0.49), television (aOR, 0.45; 95% CI: 0.24-0.83), and sirens (aOR, 0.50; 95% CI: 0.30-0.85) decreased the odds of injury, and residents frequently exposed to tornado sirens had lower odds of injury. The prevalence of PTSD in respondents was 22.1% and screening positive for PTSD symptoms was associated with tornado-related loss events.
Conclusions: Primary prevention, particularly improved shelter access, and media warnings, seem essential to prevent severe tornado-injury. Small rooms such as bathrooms may provide some protection within permanent homes when no underground shelter is available.
C1 [Niederkrotenthaler, Thomas; Parker, Erin M.; Ovalle, Fernando; Bell, Jeneita; Sugerman, David E.] Ctr Dis Control & Prevent CDC, Natl Ctr Injury Prevent & Control, Div Unintent Injury Prevent, Atlanta, GA USA.
[Niederkrotenthaler, Thomas; Parker, Erin M.] Ctr Dis Control & Prevent CDC, Sci Educ & Profess Dev Program Off, Div Appl Sci, Epidem Intelligence Serv, Atlanta, GA USA.
[Noe, Rebecca E.] Ctr Dis Control & Prevent CDC, Natl Ctr Environm Hlth, Div Environm Hazards & Hlth Effects, Atlanta, GA USA.
[Xu, Likang] Ctr Dis Control & Prevent CDC, Natl Ctr Injury Prevent & Control, Div Anal Res & Practice Integrat, Atlanta, GA USA.
[Morrison, Melissa A.] Ctr Dis Control & Prevent CDC, Off Publ Hlth Preparedness & Response, Atlanta, GA USA.
[Morrison, Melissa A.] Alabama Dept Publ Hlth, Montgomery, AL 36102 USA.
[Mertzlufft, Caitlin E.] ATSDR, Div Toxicol & Human Hlth Sci, Geospatial Res Anal & Serv Program, Atlanta, GA USA.
RP Niederkrotenthaler, T (reprint author), Med Univ Vienna, Dept Gen Practice & Family Med, Ctr Publ Hlth, Vienna, Austria.
EM thomas.niederkrotenthaler@meduniwien.ac.at
OI Niederkrotenthaler, Thomas/0000-0001-9550-628X
NR 44
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Z9 4
U1 0
U2 12
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 18
PY 2013
VL 8
IS 12
AR e83038
DI 10.1371/journal.pone.0083038
PG 10
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 276HL
UT WOS:000328740300092
PM 24367581
ER
PT J
AU Querec, TD
Gurbaxani, BM
Unger, ER
AF Querec, Troy David
Gurbaxani, Brian Mohan
Unger, Elizabeth Robinson
TI Randomization Modeling to Ascertain Clustering Patterns of Human
Papillomavirus Types Detected in Cervicovaginal Samples in the United
States
SO PLOS ONE
LA English
DT Article
ID GENITAL HUMAN-PAPILLOMAVIRUS; CERVICAL NEOPLASIA; HPV TYPES; HIGH-RISK;
YOUNG-WOMEN; INFECTION; PREVALENCE; COINFECTION; CANCER; ABNORMALITIES
AB Detection of multiple human papillomavirus (HPV) types in the genital tract is common. Associations among HPV types may impact HPV vaccination modeling and type replacement. The objectives were to determine the distribution of concurrent HPV type infections in cervicovaginal samples and examine type-specific associations. We analyzed HPV genotyping results from 32,245 cervicovaginal specimens collected from women aged 11 to 83 years in the United States from 2001 through 2011. Statistical power was enhanced by combining 6 separate studies. Expected concurrent infection frequencies from a series of permutation models, each with increasing fidelity to the real data, were compared with the observed data. Statistics were computed based on the distributional properties of the randomized data. Concurrent detection occurred more than expected with 0 or >= 3 HPV types and less than expected with 1 and 2 types. Some women bear a disproportionate burden of the HPV type prevalence. Type associations were observed that exceeded multiple hypothesis corrected significance. Multiple HPV types were detected more frequently than expected by chance and associations among particular HPV types were detected. However vaccine-targeted types were not specifically affected, supporting the expectation that current bivalent/quadrivalent HPV vaccination will not result in type replacement with other high-risk types.
C1 [Querec, Troy David; Gurbaxani, Brian Mohan; Unger, Elizabeth Robinson] Ctr Dis Control & Prevent, Chron Viral Dis Branch, Div High Consequence Pathogens & Pathol, Atlanta, GA 30329 USA.
RP Querec, TD (reprint author), Ctr Dis Control & Prevent, Chron Viral Dis Branch, Div High Consequence Pathogens & Pathol, Atlanta, GA 30329 USA.
EM tquerec@cdc.gov
OI Unger, Elizabeth/0000-0002-2925-5635
FU American Society for Microbiology/Centers for Disease Control and
Prevention Postdoctoral Research Fellowship Program
FX The stipend for Dr. Querec was provided by the American Society for
Microbiology/Centers for Disease Control and Prevention Postdoctoral
Research Fellowship Program. All data were previously collected for
other purposes by the Centers for Disease Control and Prevention. The
funders had no role in study design, aggregating previously collected
data and analysis, decision to publish, or preparation of the
manuscript.
NR 39
TC 3
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U1 0
U2 3
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 18
PY 2013
VL 8
IS 12
AR e82761
DI 10.1371/journal.pone.0082761
PG 10
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 276HL
UT WOS:000328740300066
PM 24367553
ER
PT J
AU Samji, H
Cescon, A
Hogg, RS
Modur, SP
Althoff, KN
Buchacz, K
Burchell, AN
Cohen, M
Gebo, KA
Gill, MJ
Justice, A
Kirk, G
Klein, MB
Korthuis, PT
Martin, J
Napravnik, S
Rourke, SB
Sterling, TR
Silverberg, MJ
Deeks, S
Jacobson, LP
Bosch, RJ
Kitahata, MM
Goedert, JJ
Moore, R
Gange, SJ
AF Samji, Hasina
Cescon, Angela
Hogg, Robert S.
Modur, Sharada P.
Althoff, Keri N.
Buchacz, Kate
Burchell, Ann N.
Cohen, Mardge
Gebo, Kelly A.
Gill, M. John
Justice, Amy
Kirk, Gregory
Klein, Marina B.
Korthuis, P. Todd
Martin, Jeff
Napravnik, Sonia
Rourke, Sean B.
Sterling, Timothy R.
Silverberg, Michael J.
Deeks, Stephen
Jacobson, Lisa P.
Bosch, Ronald J.
Kitahata, Mari M.
Goedert, James J.
Moore, Richard
Gange, Stephen J.
CA North Amer AIDS Cohort
TI Closing the Gap: Increases in Life Expectancy among Treated HIV-Positive
Individuals in the United States and Canada
SO PLOS ONE
LA English
DT Article
ID ACTIVE ANTIRETROVIRAL THERAPY; INJECTING DRUG-USERS; INFECTED PERSONS;
INCOME COUNTRIES; COHORT; INEQUALITIES; MORTALITY; SURVIVAL; TIME
AB Background: Combination antiretroviral therapy (ART) has significantly increased survival among HIV-positive adults in the United States (U. S.) and Canada, but gains in life expectancy for this region have not been well characterized. We aim to estimate temporal changes in life expectancy among HIV-positive adults on ART from 2000-2007 in the U. S. and Canada.
Methods: Participants were from the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD), aged >= 20 years and on ART. Mortality rates were calculated using participants' person-time from January 1, 2000 or ART initiation until death, loss to follow-up, or administrative censoring December 31, 2007. Life expectancy at age 20, defined as the average number of additional years that a person of a specific age will live, provided the current age-specific mortality rates remain constant, was estimated using abridged life tables.
Results: The crude mortality rate was 19.8/1,000 person-years, among 22,937 individuals contributing 82,022 person-years and 1,622 deaths. Life expectancy increased from 36.1 [standard error (SE) 0.5] to 51.4 [SE 0.5] years from 2000-2002 to 2006-2007. Men and women had comparable life expectancies in all periods except the last (2006-2007). Life expectancy was lower for individuals with a history of injection drug use, non-whites, and in patients with baseline CD4 counts <350 cells/mm(3).
Conclusions: A 20-year-old HIV-positive adult on ART in the U. S. or Canada is expected to live into their early 70 s, a life expectancy approaching that of the general population. Differences by sex, race, HIV transmission risk group, and CD4 count remain.
C1 [Samji, Hasina; Cescon, Angela; Hogg, Robert S.] British Columbia Ctr Excellence HIV AIDS, Vancouver, BC, Canada.
[Hogg, Robert S.] Simon Fraser Univ, Burnaby, BC V5A 1S6, Canada.
[Modur, Sharada P.; Althoff, Keri N.; Gebo, Kelly A.; Kirk, Gregory; Jacobson, Lisa P.; Moore, Richard; Gange, Stephen J.] Johns Hopkins Univ, Baltimore, MD USA.
[Buchacz, Kate] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Burchell, Ann N.; Rourke, Sean B.] Ontario HIV Treatment Network, Toronto, ON, Canada.
[Cohen, Mardge] Bur Hlth Serv Cook Cty, Core Ctr, Chicago, IL USA.
[Gill, M. John] Univ Calgary, Calgary, AB, Canada.
[Justice, Amy] Vet Adm Connecticut Healthcare Syst, West Haven, CT USA.
[Justice, Amy] Yale Univ, West Haven, CT USA.
[Klein, Marina B.] McGill Univ, Ctr Hlth, Montreal, PQ, Canada.
[Korthuis, P. Todd] Oregon Hlth & Sci Univ, Portland, OR 97201 USA.
[Martin, Jeff] Univ Calif San Francisco, San Francisco, CA 94143 USA.
[Napravnik, Sonia] Univ N Carolina, Chapel Hill, NC USA.
[Sterling, Timothy R.] Vanderbilt Univ, Nashville, TN 37235 USA.
[Silverberg, Michael J.] Kaiser Permanente No Calif, Oakland, CA USA.
[Deeks, Stephen] Univ Calif San Francisco, San Francisco Gen Hosp, San Francisco, CA USA.
[Bosch, Ronald J.] Harvard Univ, Sch Publ Hlth, Boston, MA 02115 USA.
[Kitahata, Mari M.] Univ Washington, Seattle, WA 98195 USA.
[Goedert, James J.] NCI, Rockville, MD USA.
RP Hogg, RS (reprint author), British Columbia Ctr Excellence HIV AIDS, Vancouver, BC, Canada.
EM rhogg@sfu.ca
RI Gill, John/G-7083-2016;
OI Gill, John/0000-0002-8546-8790; Gange, Stephen/0000-0001-7842-512X;
Hogg, Robert/0000-0003-3463-5488
FU National Institutes of Health [U01-AI069918, U10-AA13566, U01-AI31834,
U01-AI34989, U01-AI34993, U01-AI34994, U01-AI35004, U01-AI35039,
U01-AI35040, U01-AI35041, U01-AI35042, U01-AI35043, U01-AI37613,
U01-AI37984, U01-AI38855, U01-AI38858, U01-AI42590, U01-AI68634,
U01-AI68636, U01-HD32632, U10-EY08057, U10-EY08052, U10-EY08067,
UL1-RR024131, M01-RR-00052, M01-RR00071, M01-RR00079, M01-RR00083,
M01-RR00722, M01-RR025747, P30-AI27757, P30-AI27767, P30-AI27763,
P30-AI50410, P30-AI54999, R01-DA04334, R01-DA12568, R01-DA11602,
R01-AA16893, R24-AI067039, Z01-CP010176, AHQ290-01-0012, N02-CP55504,
AI-69432, AI-69434, K01-AI071725, K23-AI610320, K23-EY013707,
K24-DA00432, K24 AI65298, K01-AI093197]; Agency for Healthcare Research
and Quality [290-01-0012]; CDC [CDC200-2006-18797]; Canadian Institutes
of Health Research [TGF-96118, HCP-97105, CBR-86906, CBR-94036,
KRS-86251, 169621]; Canadian HIV Trials Network [24]; government of
British Columbia
FX This work was supported by grants U01-AI069918, U10-AA13566,
U01-AI31834, U01-AI34989, U01-AI34993, U01-AI34994, U01-AI35004,
U01-AI35039, U01-AI35040, U01-AI35041, U01-AI35042, U01-AI35043,
U01-AI37613, U01-AI37984, U01-AI38855, U01-AI38858, U01-AI42590,
U01-AI68634, U01-AI68636, U01-HD32632, U10-EY08057, U10-EY08052,
U10-EY08067, UL1-RR024131, UL1-RR024131, M01-RR-00052, M01-RR00071,
M01-RR00079, M01-RR00083, M01-RR00722, M01-RR025747, P30-AI27757,
P30-AI27767, P30-AI27763, P30-AI50410, P30-AI54999, R01-DA04334,
R01-DA12568, R01-DA11602, R01-AA16893, R24-AI067039, Z01-CP010176,
AHQ290-01-0012, N02-CP55504, AI-69432, AI-69434, K01-AI071725,
K23-AI610320, K23-EY013707, K24-DA00432, K24 AI65298 and K01-AI093197
from the National Institutes of Health; contract 290-01-0012 from the
Agency for Healthcare Research and Quality; contract CDC200-2006-18797
from the CDC; grants TGF-96118, HCP-97105, CBR-86906, CBR-94036,
KRS-86251, and 169621 from the Canadian Institutes of Health Research;
the Canadian HIV Trials Network, project 24; and the government of
British Columbia. The funders had no role in study design, data
collection and analysis, decision to publish, or preparation of the
manuscript.
NR 31
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PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 18
PY 2013
VL 8
IS 12
AR e81355
DI 10.1371/journal.pone.0081355
PG 8
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 276HL
UT WOS:000328740300004
PM 24367482
ER
PT J
AU Krause, PR
Bialek, SR
Boppana, SB
Griffiths, PD
Laughlin, CA
Ljungman, P
Mocarski, ES
Pass, RF
Read, JS
Schleiss, MR
Plotkin, SA
AF Krause, Philip R.
Bialek, Stephanie R.
Boppana, Suresh B.
Griffiths, Paul D.
Laughlin, Catherine A.
Ljungman, Per
Mocarski, Edward S.
Pass, Robert F.
Read, Jennifer S.
Schleiss, Mark R.
Plotkin, Stanley A.
TI Priorities for CMV vaccine development
SO VACCINE
LA English
DT Review
DE Cytomegalovirus; Congenital CMV; Viruses; Clinical trial endpoints;
Meeting report
ID CONGENITAL CYTOMEGALOVIRUS-INFECTION; ORGAN TRANSPLANT RECIPIENTS;
BONE-MARROW-TRANSPLANTATION; STEM-CELL TRANSPLANTATION; GLYCOPROTEIN-B
VACCINE; DOUBLE-BLIND; ADVISORY-COMMITTEE; HEARING-LOSS; DISEASE;
IMMUNIZATION
AB A multidisciplinary meeting addressed priorities related to development of vaccines against cytomegalovirus (CMV), the cause of congenital CMV (cCMV) disease and of serious disease in the immunocompromised. Participants discussed optimal uses of a CMV vaccine, aspects of clinical study design, and the value of additional research. A universal childhood CMV vaccine could potentially rapidly reduce cCMV disease, as infected children are sources of viral transmission to seronegative and seropositive mothers. A vaccine administered to adolescents or adult women could also reduce cCMV disease by making them immune prior to pregnancy. Clinical trials of CMV vaccines in women should evaluate protection against cCMV infection, an essential precursor of cCMV disease, which is a more practical and acceptable endpoint for assessing vaccine effects on maternal-fetal transmission. Clinical trials of vaccines to evaluate prevention of CMV disease in stem cell transplant recipients could use CMV viremia at a level triggering pre-emptive antiviral therapy as an endpoint, because widespread use of pre-emptive and prophylactic antivirals has rendered CMV-induced disease too rare to be a practical endpoint for clinical trials. In solid organ transplant patients, CMV-associated disease is sufficiently common for use as a primary endpoint. Additional research to advance CMV vaccine development should include identifying factors that predict fetal loss due to CMV, determining age-specific incidence and transmission rates, defining the mechanism and relative contributions of maternal reactivation and reinfection to cCMV disease, developing assays that can distinguish between reactivation and re-infection in seropositive vaccinees, further defining predictors of sequelae from cCMV infection, and identifying clinically relevant immune response parameters to CMV (including developing validated assays that could assess CMV antibody avidity) that could lead to the establishment of immune correlates of protection. Published by Elsevier Ltd.
C1 [Krause, Philip R.] US FDA, Off Vaccines Res & Review, CBER, Bethesda, MD 20014 USA.
[Bialek, Stephanie R.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Boppana, Suresh B.; Pass, Robert F.] Univ Alabama Birmingham, Birmingham, AL USA.
[Griffiths, Paul D.] UCL, London WC1E 6BT, England.
[Laughlin, Catherine A.] NIAID, NIH, Bethesda, MD USA.
[Ljungman, Per] Karolinska Inst, Stockholm, Sweden.
[Mocarski, Edward S.] Emory Univ, Atlanta, GA 30322 USA.
[Read, Jennifer S.] Natl Vaccine Program Off, Washington, DC USA.
[Schleiss, Mark R.] Univ Minnesota, Minneapolis, MN USA.
[Plotkin, Stanley A.] Univ Penn, Philadelphia, PA 19104 USA.
RP Krause, PR (reprint author), US FDA, Off Vaccines Res & Review, CBER, 29 Lincoln Dr, Bethesda, MD 20014 USA.
EM philip.krause@fda.hhs.gov; zqg7@cdc.gov; sboppana@peds.uab.edu;
p.griffiths@ucl.ac.uk; CLaughlin@niaid.nih.gov; Per.Ljungman@ki.se;
mocarski@emory.edu; RPass@peds.uab.edu; Jennifer.Read@fda.hhs.gov;
schleiss@umn.edu; stanley.plotkin@vaxconsult.com
OI Krause, Philip/0000-0002-1045-7536
FU Food and Drug Administration; National Institutes of Health; Centers for
Disease Control and Prevention; National Vaccine Program Office
FX We acknowledge the Food and Drug Administration, the National Institutes
of Health, the Centers for Disease Control and Prevention, and the
National Vaccine Program Office for sponsorship of the CMV Vaccine
Workshop, held in Bethesda, MD on the NIH Campus on January 11-12, 2012.
We also thank the presenters and participants at the meeting for
excellent discussions that enabled a highly productive meeting.
NR 55
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U2 7
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 17
PY 2013
VL 32
IS 1
BP 4
EP 10
DI 10.1016/j.vaccine.2013.09.042
PG 7
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 289LT
UT WOS:000329684700003
PM 24129123
ER
PT J
AU Fitter, DL
Anselme, R
Paluku, G
Rey, G
Flannery, B
Tohme, RA
Marston, BJ
Griswold, M
Boncy, J
Vertefeuille, JF
AF Fitter, David L.
Anselme, Renette
Paluku, Gilson
Rey, Gloria
Flannery, Brendan
Tohme, Rania A.
Marston, Barbara J.
Griswold, Mark
Boncy, Jacques
Vertefeuille, John F.
TI Seroprevalence of measles and rubella antibodies in pregnant women
Haiti, 2012
SO VACCINE
LA English
DT Article
DE Measles; Rubella; Seroprevalence; Vaccine; IgG antibody
ID VACCINATION CAMPAIGN; ELIMINATION
AB Background: Haiti had set a national goal to eliminate measles and rubella, as well as congenital rubella syndrome (CRS) by 2010. A 2007-2008 nationwide measles and rubella vaccination campaign targeting 1-19 years, however, reached only 79% of the target population. To assess whether population immunity was adequate to support elimination, we conducted a national serosurvey.
Methods: We systematically selected 740 serum specimens collected from pregnant women in a 2012 national antenatal HIV sentinel serosurvey across four age strata: 15-19, 20-24, 25-29 and 30-39 years. Sera were tested for measles and rubella specific immunoglobulin G antibodies (IgG) using commercial immunoassays. We classified sera as seropositive, seronegative or indeterminate per manufacturer's instructions, and analyzed seroprevalence according to age strata, and rural or urban residence. We assessed immunity by estimating antibody concentrations in international units per milliliter (IU/mL) for seropositive and indeterminate sera. Measles IgG concentrations >0.12 IU/mL and rubella IgG concentrations >10 IU/mL were considered clinically protective.
Results: Of 740 sera, 696 (94.1%) were seropositive and 20 (2.7%) were indeterminate for measles IgG; overall 716 (96.8%) sera had IgG concentrations >0.12 IU/mL. For rubella IgG, 691 (93.4%) sera were seropositive and 1(0.1%) was indeterminate; a total of 687 (92.8%) had IgG concentrations >10 IU/mL. Measles seropositivity varied across age strata (p = 0.003); seropositivity increased from 88.6% among 15-19 year olds to 98.4% among 30-39 year olds (Cochran-Armitage trend test <= 0.0001). Rubella seropositivity did not differ across age strata. There were no statistically significant differences in measles or rubella seropositivity by urban versus rural residence.
Conclusion: Despite previous low vaccination coverage for measles, results from this serosurvey indicate high levels of measles and rubella seropositivity in pregnant women, and contribute to the evidence for measles, rubella and CRS elimination from Haiti by the target date. Published by Elsevier Ltd.
C1 [Fitter, David L.; Marston, Barbara J.] Ctr Dis Control & Prevent, Div Global Hlth Protect, Ctr Global Hlth, Atlanta, GA 30333 USA.
[Fitter, David L.] Ctr Dis Control & Prevent, Epidem Intelligence Serv Program, Atlanta, GA 30333 USA.
[Paluku, Gilson] Pan Amer Hlth Org, Port Au Prince, Haiti.
[Rey, Gloria] Pan Amer Hlth Org, San Jose, Costa Rica.
[Flannery, Brendan; Tohme, Rania A.] Ctr Dis Control & Prevent, Global Immunizat Div, Ctr Global Hlth, Atlanta, GA 30333 USA.
[Griswold, Mark] Natl Alliance State & Territorial AIDS Directors, Global Program, Washington, DC USA.
[Vertefeuille, John F.] US Ctr Dis Control & Prevent, Haiti Country Off, Port Au Prince, Haiti.
RP Fitter, DL (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd NE,Mailstop A-05, Atlanta, GA 30333 USA.
EM dfitter@cdc.gov
FU Centers for Disease Control and Prevention; Pan American Health
Organization
FX This work was supported by the Centers for Disease Control and
Prevention and the Pan American Health Organization.
NR 15
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U1 1
U2 2
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 17
PY 2013
VL 32
IS 1
BP 69
EP 73
DI 10.1016/j.vaccine.2013.10.071
PG 5
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 289LT
UT WOS:000329684700012
PM 24188751
ER
PT J
AU Quashie, NB
Duah, NO
Abuaku, B
Quaye, L
Ayanful-Torgby, R
Akwoviah, GA
Kweku, M
Johnson, JD
Lucchi, NW
Udhayakumar, V
Duplessis, C
Kronmann, KC
Koram, KA
AF Quashie, Neils B.
Duah, Nancy O.
Abuaku, Benjamin
Quaye, Lydia
Ayanful-Torgby, Ruth
Akwoviah, George A.
Kweku, Margaret
Johnson, Jacob D.
Lucchi, Naomi W.
Udhayakumar, Venkatachalam
Duplessis, Christopher
Kronmann, Karl C.
Koram, Kwadwo A.
TI A SYBR Green 1-based in vitro test of susceptibility of Ghanaian
Plasmodium falciparum clinical isolates to a panel of anti-malarial
drugs
SO MALARIA JOURNAL
LA English
DT Article
DE Isolates; in vitro; Susceptibility; Inhibition; Plasmodium falciparum
ID CHLOROQUINE RESISTANCE; UNCOMPLICATED MALARIA; PFMDR1 GENE; MEFLOQUINE;
AFRICA; MUTATIONS; EFFICACY; ASSAY; WEST; ANTIBIOTICS
AB Background: Based on report of declining efficacy of chloroquine, Ghana shifted to the use of artemisinin-based combination therapy (ACT) in 2005 as the first-line anti-malarial drug. Since then, there has not been any major evaluation of the efficacy of anti-malarial drugs in Ghana in vitro. The sensitivity of Ghanaian Plasmodium falciparum isolates to anti-malarial drugs was, therefore, assessed and the data compared with that obtained prior to the change in the malaria treatment policy.
Methods: A SYBR Green 1 fluorescent-based in vitro drug sensitivity assay was used to assess the susceptibility of clinical isolates of P. falciparum to a panel of 12 anti-malarial drugs in three distinct eco-epidemiological zones in Ghana. The isolates were obtained from children visiting health facilities in sentinel sites located in Hohoe, Navrongo and Cape Coast municipalities. The concentration of anti-malarial drug inhibiting parasite growth by 50% (IC50) for each drug was estimated using the online program, ICEstimator.
Results: Pooled results from all the sentinel sites indicated geometric mean IC50 values of 1.60, 3.80, 4.00, 4.56, 5.20, 6.11, 10.12, 28.32, 31.56, 93.60, 107.20, and 8952.50 nM for atovaquone, artesunate, dihydroartemisin, artemether, lumefantrine, amodiaquine, mefloquine, piperaquine, chloroquine, tafenoquine, quinine, and doxycycline, respectively. With reference to the literature threshold value indicative of resistance, the parasites showed resistance to all the test drugs except the artemisinin derivatives, atovaquone and to a lesser extent, lumefantrine. There was nearly a two-fold decrease in the IC50 value determined for chloroquine in this study compared to that determined in 2004 (57.56 nM). This observation is important, since it suggests a significant improvement in the efficacy of chloroquine, probably as a direct consequence of reduced drug pressure after cessation of its use. Compared to that measured prior to the change in treatment policy, significant elevation of artesunate IC50 value was observed. The results also suggest the existence of possible cross-resistance among some of the test drugs.
Conclusion: Ghanaian P. falciparum isolates, to some extent, have become susceptible to chloroquine in vitro, however the increasing trend in artesunate IC50 value observed should be of concern. Continuous monitoring of ACT in Ghana is recommended.
C1 [Quashie, Neils B.] Univ Ghana, Sch Med, Ctr Trop Clin Pharmacol & Therapeut, Accra, Ghana.
[Quashie, Neils B.; Duah, Nancy O.; Abuaku, Benjamin; Quaye, Lydia; Ayanful-Torgby, Ruth; Akwoviah, George A.; Koram, Kwadwo A.] Univ Ghana, Noguchi Mem Inst Med Res, Dept Epidemiol, Accra, Ghana.
[Duplessis, Christopher; Kronmann, Karl C.] US Naval Med Res Unit 3, Cairo, Egypt.
[Kweku, Margaret] Hohoe Hlth Res Ctr, Hohoe, Ghana.
[Johnson, Jacob D.] US Army Med Res Unit Kenya, Kenya Med Res Inst, Walter Reed Project, Dept Emerging,Infect Dis Program, Kisumu, Kenya.
[Lucchi, Naomi W.; Udhayakumar, Venkatachalam] Ctr Dis Control & Prevent, Div Parasit Dis & Malaria, Atlanta, GA USA.
RP Quashie, NB (reprint author), Univ Ghana, Sch Med, Ctr Trop Clin Pharmacol & Therapeut, Accra, Ghana.
EM nquashie@noguchi.ug.edu.gh
OI Duah, Nancy/0000-0001-8819-1793
FU Global Emerging Infections Surveillance and Response System (GEIS), a
Division of the Armed Forces Health Surveillance Center (AFHSC)
[C0437_11_N3]; Global Fund
FX The Global Emerging Infections Surveillance and Response System (GEIS),
a Division of the Armed Forces Health Surveillance Center (AFHSC)
[Project no. C0437_11_N3] funded this work. WWARN is acknowledged for
providing the anti-malarial drugs used in this study. We also thank CDC
for donating a field-based customized fluorescence plate reader for the
project and training. We thank Dr Jacob Johnson and Mr Hosea Akala
(Department of Emerging Infectious Diseases Program, US Army Medical
Research Unit-Kenya, Kenya Medical Research Institute-Walter Reed
Project, Kisumu, Kenya) for training the NMIMR Group on the use of the
SYBR Green method. We also thank the teams in Hohoe Municipal Hospital,
Likpe-Bakwa Health Centre, Navrongo War Memorial Hospital, Ewim Health
Centre, Cape Coast and Central Regional Hospital. We acknowledge the
cooperation of the Navrongo Health Research. The sentinel sites were
originally set up by the Noguchi Memorial Institute for Medical Research
in collaboration with the NMCP and supported financially with the Global
Fund.
NR 55
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U2 8
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1475-2875
J9 MALARIA J
JI Malar. J.
PD DEC 17
PY 2013
VL 12
AR 450
DI 10.1186/1475-2875-12-450
PG 12
WC Infectious Diseases; Parasitology; Tropical Medicine
SC Infectious Diseases; Parasitology; Tropical Medicine
GA 281OO
UT WOS:000329111100001
PM 24341604
ER
PT J
AU King, R
Barker, J
Nakayiwa, S
Katuntu, D
Lubwama, G
Bagenda, D
Lane, T
Opio, A
Hladik, W
AF King, Rachel
Barker, Joseph
Nakayiwa, Sylvia
Katuntu, David
Lubwama, George
Bagenda, Danstan
Lane, Tim
Opio, Alex
Hladik, Wolfgang
TI Men at Risk; a Qualitative Study on HIV Risk, Gender Identity and
Violence among Men Who Have Sex with Men Who Report High Risk Behavior
in Kampala, Uganda
SO PLOS ONE
LA English
DT Article
ID SUB-SAHARAN AFRICA; BISEXUAL MEN; SOUTH-AFRICA; WORKERS; KENYA;
HIV/AIDS; MOMBASA; GAY
AB In Uganda, men who have sex with men (MSM) are at high risk for HIV. Between May 2008 and February 2009 in Kampala, Uganda, we used respondent driven sampling (RDS) to recruit 295 MSM >= 18 years who reported having had sex with another man in the preceding three months. The parent study conducted HIV and STI testing and collected demographic and HIV-related behavioral data through audio computer-assisted self-administered interviews. We conducted a nested qualitative sub-study with 16 men purposively sampled from among the survey participants based on responses to behavioral variables indicating higher risk for HIV infection. Sub-study participants were interviewed face-to-face. Domains of inquiry included sexual orientation, gender identity, condom use, stigma, discrimination, violence and health seeking behavior. Emergent themes included a description of sexual orientation/gender identity categories. All groups of men described conflicting feelings related to their sexual orientation and contextual issues that do not accept same-sex identities or behaviors and non-normative gender presentation. The emerging domains for facilitating condom use included: lack of trust in partner and fear of HIV infection. We discuss themes in the context of social and policy issues surrounding homosexuality and HIV prevention in Uganda that directly affect men's lives, risk and health-promoting behaviors.
C1 [King, Rachel; Lane, Tim] Univ Calif San Francisco, Global Hlth Sci, San Francisco, CA 94143 USA.
[King, Rachel; Barker, Joseph; Nakayiwa, Sylvia; Katuntu, David; Hladik, Wolfgang] Ctr Dis Control & Prevent CDC, Ctr Global Hlth, Div Global HIV AIDS, Entebbe, Uganda.
[Lubwama, George; Bagenda, Danstan] Makerere Univ, Sch Publ Hlth MakSPH, Kampala, Uganda.
[Opio, Alex; Hladik, Wolfgang] Univ Amsterdam, Acad Med Ctr, Dept Clin Epidemiol, NL-1012 WX Amsterdam, Netherlands.
Minist Hlth, Kampala, Uganda.
[Barker, Joseph; Hladik, Wolfgang] Ctr Dis Control & Prevent CDC, Ctr Global Hlth, Div Global HIV AIDS, Atlanta, GA USA.
RP King, R (reprint author), Univ Calif San Francisco, Global Hlth Sci, San Francisco, CA 94143 USA.
EM rlking@psg.ucsf.edu
FU US President's Emergency Plan for AIDS Relief
FX This study was funded by the US President's Emergency Plan for AIDS
Relief. The funders had no role in study design, data collection and
analysis, decision to publish, or preparation of the manuscript.
NR 29
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U1 1
U2 19
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 17
PY 2013
VL 8
IS 12
AR e82937
DI 10.1371/journal.pone.0082937
PG 8
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 276GT
UT WOS:000328737700040
PM 24358239
ER
PT J
AU Phinney, KW
Ballihaut, G
Bedner, M
Benford, BS
Camara, JE
Christopher, SJ
Davis, WC
Dodder, NG
Eppe, G
Lang, BE
Long, SE
Lowenthal, MS
McGaw, EA
Murphy, KE
Nelson, BC
Prendergast, JL
Reiner, JL
Rimmer, CA
Sander, LC
Schantz, MM
Sharpless, KE
Sniegoski, LT
Tai, SSC
Thomas, JB
Vetter, TW
Welch, MJ
Wise, SA
Wood, LJ
Guthrie, WF
Hagwood, CR
Leigh, SD
Yen, JH
Zhang, NF
Chaudhary-Webb, M
Chen, HP
Fazili, Z
LaVoie, DJ
McCoy, LF
Momin, SS
Paladugula, N
Pendergrast, EC
Pfeiffer, CM
Powers, CD
Rabinowitz, D
Rybak, ME
Schleicher, RL
Toombs, BMH
Xu, M
Zhang, M
Castle, AL
AF Phinney, Karen W.
Ballihaut, Guillaume
Bedner, Mary
Benford, Brandi S.
Camara, Johanna E.
Christopher, Steven J.
Davis, W. Clay
Dodder, Nathan G.
Eppe, Gauthier
Lang, Brian E.
Long, Stephen E.
Lowenthal, Mark S.
McGaw, Elizabeth A.
Murphy, Karen E.
Nelson, Bryant C.
Prendergast, Jocelyn L.
Reiner, Jessica L.
Rimmer, Catherine A.
Sander, Lane C.
Schantz, Michele M.
Sharpless, Katherine E.
Sniegoski, Lorna T.
Tai, Susan S. -C.
Thomas, Jeanice B.
Vetter, Thomas W.
Welch, Michael J.
Wise, Stephen A.
Wood, Laura J.
Guthrie, William F.
Hagwood, Charles R.
Leigh, Stefan D.
Yen, James H.
Zhang, Nien-Fan
Chaudhary-Webb, Madhu
Chen, Huiping
Fazili, Zia
LaVoie, Donna J.
McCoy, Leslie F.
Momin, Shahzad S.
Paladugula, Neelima
Pendergrast, Elizabeth C.
Pfeiffer, Christine M.
Powers, Carissa D.
Rabinowitz, Daniel
Rybak, Michael E.
Schleicher, Rosemary L.
Toombs, Bridgette M. H.
Xu, Mary
Zhang, Mindy
Castle, Arthur L.
TI Development of a Standard Reference Material for Metabolomics Research
SO ANALYTICAL CHEMISTRY
LA English
DT Article
ID HUMAN PLASMA; MASS-SPECTROMETRY; HUMAN URINE; METABONOMIC ANALYSIS;
DIABETES-MELLITUS; ACID-METABOLISM; HPLC-MS; DISEASE; SPECTROSCOPY;
PERFORMANCE
AB The National Institute of Standards and Technology (NIST), in collaboration with the National Institutes of Health (NTH), has developed a Standard Reference Material (SRM) to support technology development in metabolomics research. SRM 1950 Metabolites in Human Plasma is intended to have metabolite concentrations that are representative of those found in adult human plasma. The plasma used in the preparation of SRM 1950 was collected from both male and female donors, and donor ethnicity targets were selected based upon the ethnic makeup of the U.S. population. Metabolomics research is diverse in terms of both instrumentation and scientific goals. This SRM was designed to apply broadly to the field, not toward specific applications. Therefore, concentrations of approximately 100 analytes, including amino acids, fatty acids, trace elements, vitamins, hormones, selenoproteins, clinical markers, and perfluorinated compounds (PFCs), were determined. Value assignment measurements were performed by NIST and the Centers for Disease Control and Prevention (CDC). SRM 1950 is the first reference material developed specifically for metabolomics research.
C1 [Phinney, Karen W.; Lowenthal, Mark S.] NIST, Biomol Measurement Div, Gaithersburg, MD 20899 USA.
[Ballihaut, Guillaume; Bedner, Mary; Benford, Brandi S.; Camara, Johanna E.; Christopher, Steven J.; Davis, W. Clay; Dodder, Nathan G.; Eppe, Gauthier; Long, Stephen E.; McGaw, Elizabeth A.; Murphy, Karen E.; Prendergast, Jocelyn L.; Reiner, Jessica L.; Rimmer, Catherine A.; Sander, Lane C.; Schantz, Michele M.; Sharpless, Katherine E.; Sniegoski, Lorna T.; Tai, Susan S. -C.; Thomas, Jeanice B.; Vetter, Thomas W.; Welch, Michael J.; Wise, Stephen A.; Wood, Laura J.] NIST, Div Chem Sci, Gaithersburg, MD 20899 USA.
[Lang, Brian E.; Nelson, Bryant C.] NIST, Biosyst & Biomat Div, Gaithersburg, MD 20899 USA.
[Guthrie, William F.; Hagwood, Charles R.; Leigh, Stefan D.; Yen, James H.; Zhang, Nien-Fan] NIST, Stat Engn Div, Gaithersburg, MD 20899 USA.
[Chaudhary-Webb, Madhu; Chen, Huiping; Fazili, Zia; LaVoie, Donna J.; McCoy, Leslie F.; Momin, Shahzad S.; Paladugula, Neelima; Pendergrast, Elizabeth C.; Pfeiffer, Christine M.; Powers, Carissa D.; Rabinowitz, Daniel; Rybak, Michael E.; Schleicher, Rosemary L.; Toombs, Bridgette M. H.; Xu, Mary; Zhang, Mindy] Ctr Dis Control & Prevent, Div Sci Lab, Natl Ctr Environm Hlth, Atlanta, GA 30341 USA.
[Castle, Arthur L.] NIDDK, NIH, Bethesda, MD 20892 USA.
RP Phinney, KW (reprint author), NIST, Biomol Measurement Div, Gaithersburg, MD 20899 USA.
EM karen.phinney@nist.gov
RI Dodder, Nathan/C-7971-2015;
OI Dodder, Nathan/0000-0001-5913-1767; Rybak, Michael/0000-0003-1650-8581
FU Intramural CDC HHS [CC999999]
NR 62
TC 21
Z9 21
U1 6
U2 53
PU AMER CHEMICAL SOC
PI WASHINGTON
PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
SN 0003-2700
EI 1520-6882
J9 ANAL CHEM
JI Anal. Chem.
PD DEC 17
PY 2013
VL 85
IS 24
BP 11732
EP 11738
DI 10.1021/ac402689t
PG 7
WC Chemistry, Analytical
SC Chemistry
GA 277CV
UT WOS:000328797200012
PM 24187941
ER
PT J
AU Nishizawa, M
Hattori, J
Shiino, T
Matano, T
Heneine, W
Johnson, JA
Sugiura, W
AF Nishizawa, Masako
Hattori, Junko
Shiino, Teiichiro
Matano, Tetsuro
Heneine, Walid
Johnson, Jeffrey A.
Sugiura, Wataru
TI Highly-Sensitive Allele-Specific PCR Testing Identifies a Greater
Prevalence of Transmitted HIV Drug Resistance in Japan
SO PLOS ONE
LA English
DT Article
ID IMMUNODEFICIENCY-VIRUS TYPE-1; TREATMENT-NAIVE PATIENTS; ANTIRETROVIRAL
THERAPY; REVERSE-TRANSCRIPTASE; LOW-FREQUENCY; IN-VIVO; MUTATIONS;
FITNESS; NEVIRAPINE; MUTANTS
AB Background: The transmission of drug-resistant HIV in newly identified infected populations has become an underlying epidemic which can be better assessed with sensitive resistance testing. Since minority drug resistant variants cannot be detected by bulk sequencing, methods with improved sensitivity are required. Thus, the goal of this study was to evaluate if transmitted drug resistance mutations at minority levels in Japanese patients could be identified using highly sensitive allele-specific PCR (AS-PCR).
Materials and Methods: Samples were taken from newly diagnosed HIV/AIDS cases at the National Nagoya Hospital from January 2008 to December 2009. All samples were bulk sequenced for HIV protease and reverse transcriptase. To detect minority populations with drug resistance, we used AS-PCR with mutation-specific primers designed for seven reverse transcriptase inhibitor resistance mutations, M41L, K65R, K70R, K103N, Y181C, M184V, and T215F/Y, and for three protease inhibitor resistance mutations, M46I/L and L90M.
Results: We studied 149 newly identified HIV cases. Bulk sequencing detected 8 cases with NRTI resistance mutations (one with A62V, one D67E, one T215D, one T215E, two with T215L and two T215S) and 15 with PI resistance mutations (one with N88D and 14 with M46I). Results obtained by AS-PCR and bulk sequencing demonstrated good concordance but the AS-PCR enabled the detection of seven additional drug-resistant cases (one M41L, two with K65R, two with K70R, and one M184V) in the RT region. Additionally, AS-PCR assays identified 15 additional cases with M46I, five with M46L and four cases with L90M in the protease region.
Conclusions: Using AS-PCR substantially increased the detection of transmitted drug resistance in this population from 15.4% to 26.8%, further supporting the benefit of sensitive testing among drug-naive populations. Since the clinical impact of minority drug-resistant populations is not fully comprehended for all mutations, follow-up studies are needed to understand their significance for treatment.
C1 [Nishizawa, Masako; Shiino, Teiichiro; Matano, Tetsuro; Sugiura, Wataru] Natl Inst Infect Dis, AIDS Res Ctr, Tokyo, Japan.
[Hattori, Junko; Sugiura, Wataru] Nagoya Med Ctr, Natl Hosp Org, Clin Res Ctr, Nagoya, Aichi, Japan.
[Heneine, Walid; Johnson, Jeffrey A.] Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA USA.
[Sugiura, Wataru] Nagoya Univ, Grad Sch Med, Dept AIDS Res, Nagoya, Aichi 4648601, Japan.
RP Sugiura, W (reprint author), Natl Inst Infect Dis, AIDS Res Ctr, Tokyo, Japan.
EM wsugiura@nnh.hosp.go.jp
FU Ministry of Health, Labour, and Welfare of Japan [H22-AIDS-004]
FX This work was supported by a Grant-in-Aid for AIDS research from the
Ministry of Health, Labour, and Welfare of Japan [H22-AIDS-004]. The
funders had no role in study design, data collection and analysis,
decision to publish, or preparation of the manuscript.
NR 44
TC 2
Z9 2
U1 0
U2 1
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 16
PY 2013
VL 8
IS 12
AR UNSP e83150
DI 10.1371/journal.pone.0083150
PG 10
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 276GD
UT WOS:000328735700106
PM 24358257
ER
PT J
AU Dams-O'Connor, K
Cuthbert, JP
Whyte, J
Corrigan, JD
Faul, M
Harrison-Felix, C
AF Dams-O'Connor, Kristen
Cuthbert, Jeffrey P.
Whyte, John
Corrigan, John D.
Faul, Mark
Harrison-Felix, Cynthia
TI Traumatic Brain Injury among Older Adults at Level I and II Trauma
Centers
SO JOURNAL OF NEUROTRAUMA
LA English
DT Article
DE adult brain injury; epidemiology; geriatric brain injury; traumatic
brain injury
ID PROSPECTIVE MULTICENTER TRIAL; GERIATRIC TRAUMA; UNITED-STATES;
MORTALITY; AGE; SEVERITY; CARE; HOSPITALIZATIONS; ASSOCIATION;
POPULATION
AB Individuals 65 years of age and over have the highest rates of traumatic brain injury (TBI)-related hospitalizations and deaths, and older adults (defined variably across studies) have particularly poor outcomes after TBI. The factors predicting these outcomes remain poorly understood, and age-specific care guidelines for TBI do not exist. This study provides an overview of TBI in older adults using data from the National Trauma Data Bank (NTDB) gathered between 2007 and 2010, evaluates age group-specific trends in rates of TBI over time using U.S. Census data, and examines whether routinely collected information is able to predict hospital discharge status among older adults with TBI in the NTDB. Results showed a 20-25% increase in trauma center admissions for TBI among the oldest age groups (those >=75 years), relative to the general population, between 2007 and 2010. Older adults (>=65 years) with TBI tended to be white females who have incurred an injury from a fall resulting in a severe Abbreviated Injury Scale (AIS) score of the head. Older adults had more in-hospital procedures, such as neuroimaging and neurosurgery, tended to experience longer hospital stays, and were more likely to require continued medical care than younger adults. Older age, injury severity, and hypotension increased the odds of in-hospital death. The public health burden of TBI among older adults will likely increase as the Baby Boom generation ages. Improved primary and secondary prevention of TBI in this cohort is needed.
C1 [Dams-O'Connor, Kristen] Icahn Sch Med Mt Sinai, Dept Rehabil Med, New York, NY 10029 USA.
[Cuthbert, Jeffrey P.; Harrison-Felix, Cynthia] Craig Hosp, Res Dept, Englewood, CO USA.
[Whyte, John] Albert Einstein Healthcare Network, Moss Rehabil Res Inst, Elkins Pk, PA USA.
[Corrigan, John D.] Ohio State Univ, Dept Phys Med & Rehabil, Columbus, OH 43210 USA.
[Faul, Mark] Ctr Dis Control & Prevent, Natl Ctr Injury Prevent & Control, Atlanta, GA USA.
RP Dams-O'Connor, K (reprint author), Icahn Sch Med Mt Sinai, Dept Rehabil Med, 1 Gustave Levy Pl,Box 1240B, New York, NY 10029 USA.
EM kdams13@gmail.com
NR 51
TC 14
Z9 14
U1 1
U2 5
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 0897-7151
EI 1557-9042
J9 J NEUROTRAUM
JI J. Neurotrauma
PD DEC 15
PY 2013
VL 30
IS 24
BP 2001
EP 2013
DI 10.1089/neu.2013.3047
PG 13
WC Critical Care Medicine; Clinical Neurology; Neurosciences
SC General & Internal Medicine; Neurosciences & Neurology
GA 271QK
UT WOS:000328406500001
PM 23962046
ER
PT J
AU Scinicariello, F
Buser, MC
Mevissen, M
Portier, CJ
AF Scinicariello, Franco
Buser, Melanie C.
Mevissen, Meike
Portier, Christopher J.
TI Blood lead level association with lower body weight in NHANES 1999-2006
SO TOXICOLOGY AND APPLIED PHARMACOLOGY
LA English
DT Article
DE Obesity; Body mass index; Lead; NHANES; Children; Adults
ID GROWTH STATUS; EXPOSURE; OBESITY; CHILDREN; BONE; STRESS; ONSET
AB Background: Lead exposure is associated with low birth-weight. The objective of this study is to determine whether lead exposure is associated with lower body weight in children, adolescents and adults.
Methods: We analyzed data from NHANES 1999-2006 for participants aged >= 3 using multiple logistic and multivariate linear regression. Using age- and sex-standardized BMI Z-scores, overweight and obese children (ages 3-19) were classified by BMI >= 85th and >= 95th percentiles, respectively. The adult population (age >= 20) was classified as overweight and obese with BMI measures of 25-29.9 and >= 30, respectively. Blood lead level (BLL) was categorized by weighted quartiles.
Results: Multivariate linear regressions revealed a lower BMI Z-score in children and adolescents when the highest lead quartile was compared to the lowest lead quartile (beta (SE) = -033 (0.07), p < 0.001), and a decreased BMI in adults (beta (SE) = -2.58 (025), p < 0.001). Multiple logistic analyses in children and adolescents found a negative association between BLL and the percentage of obese and overweight with BLL in the highest quartile compared to the lowest quartile (OR = 0.42, 95% CI: 030-0.59; and OR = 0.67, 95% CI: 052-0.88, respectively). Adults in the highest lead quartile were less likely to be obese (OR = 0.42,95% CI: 035-0.50) compared to those in the lowest lead quartile. Further analyses with blood lead as restricted cubic splines, confirmed the dose-relationship between blood lead and body weight outcomes.
Conclusions: BLLs are associated with lower body mass index and obesity in children, adolescents and adults. Published by Elsevier Inc.
C1 [Scinicariello, Franco; Buser, Melanie C.] Agcy Tox Subst & Dis Registry, Div Toxicol & Human Hlth Sci, Atlanta, GA USA.
[Mevissen, Meike] Univ Bern, Vetsuisse Fac, Div Vet Pharmacol & Toxicol, CH-3012 Bern, Switzerland.
[Portier, Christopher J.] CDC, Natl Ctr Environm Hlth NCEH ATSDR, Atlanta, GA 30341 USA.
RP Scinicariello, F (reprint author), Ctr Dis Control & Prevent, Agcy Tox Subst & Dis Registry, 4770 Buford Hwy,MS F61, Atlanta, GA 30341 USA.
EM fes6@cdc.gov
RI Portier, Christopher/A-3160-2010
OI Portier, Christopher/0000-0002-0954-0279
FU Research Participation Program at the Centers for Disease Control and
Prevention
FX This research was supported in part by an appointment to the Research
Participation Program at the Centers for Disease Control and Prevention
administered by the Oak Ridge Institute for Science and Education
through an interagency agreement between the U.S. Department of Energy
and CDC (MCB).
NR 37
TC 8
Z9 8
U1 0
U2 16
PU ACADEMIC PRESS INC ELSEVIER SCIENCE
PI SAN DIEGO
PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA
SN 0041-008X
EI 1096-0333
J9 TOXICOL APPL PHARM
JI Toxicol. Appl. Pharmacol.
PD DEC 15
PY 2013
VL 273
IS 3
BP 516
EP 523
DI 10.1016/j.taap.2013.09.022
PG 8
WC Pharmacology & Pharmacy; Toxicology
SC Pharmacology & Pharmacy; Toxicology
GA 275XC
UT WOS:000328711700011
PM 24099784
ER
PT J
AU Jhung, MA
Epperson, S
Biggerstaff, M
Allen, D
Balish, A
Barnes, N
Beaudoin, A
Berman, L
Bidol, S
Blanton, L
Blythe, D
Brammer, L
D'Mello, T
Danila, R
Davis, W
de Fijter, S
DiOrio, M
Durand, LO
Emery, S
Fowler, B
Garten, R
Grant, Y
Greenbaum, A
Gubareva, L
Havers, F
Haupt, T
House, J
Ibrahim, S
Jiang, V
Jain, S
Jernigan, D
Kazmierczak, J
Klimov, A
Lindstrom, S
Longenberger, A
Lucas, P
Lynfield, R
McMorrow, M
Moll, M
Morin, C
Ostroff, S
Page, SL
Park, SY
Peters, S
Quinn, C
Reed, C
Richards, S
Scheftel, J
Simwale, O
Shu, B
Soyemi, K
Stauffer, J
Steffens, C
Su, S
Torso, L
Uyeki, TM
Vetter, S
Villanueva, J
Wong, KK
Shaw, M
Bresee, JS
Cox, N
Finelli, L
AF Jhung, Michael A.
Epperson, Scott
Biggerstaff, Matthew
Allen, Donna
Balish, Amanda
Barnes, Nathelia
Beaudoin, Amanda
Berman, LaShondra
Bidol, Sally
Blanton, Lenee
Blythe, David
Brammer, Lynnette
D'Mello, Tiffany
Danila, Richard
Davis, William
de Fijter, Sietske
DiOrio, Mary
Durand, Lizette O.
Emery, Shannon
Fowler, Brian
Garten, Rebecca
Grant, Yoran
Greenbaum, Adena
Gubareva, Larisa
Havers, Fiona
Haupt, Thomas
House, Jennifer
Ibrahim, Sherif
Jiang, Victoria
Jain, Seema
Jernigan, Daniel
Kazmierczak, James
Klimov, Alexander
Lindstrom, Stephen
Longenberger, Allison
Lucas, Paul
Lynfield, Ruth
McMorrow, Meredith
Moll, Maria
Morin, Craig
Ostroff, Stephen
Page, Shannon L.
Park, Sarah Y.
Peters, Susan
Quinn, Celia
Reed, Carrie
Richards, Shawn
Scheftel, Joni
Simwale, Owen
Shu, Bo
Soyemi, Kenneth
Stauffer, Jill
Steffens, Craig
Su, Su
Torso, Lauren
Uyeki, Timothy M.
Vetter, Sara
Villanueva, Julie
Wong, Karen K.
Shaw, Michael
Bresee, Joseph S.
Cox, Nancy
Finelli, Lyn
TI Outbreak of Variant Influenza A(H3N2) Virus in the United States
SO CLINICAL INFECTIOUS DISEASES
LA English
DT Article
DE influenza; outbreak; pandemic; variant influenza
ID SWINE INFLUENZA; A H1N1; HUMAN INFECTIONS; COUNTY FAIR; PIGS;
TRANSMISSION; VACCINE; HUMANS; FERRETS; RECOMMENDATIONS
AB Background. Variant influenza virus infections are rare but may have pandemic potential if person-to-person transmission is efficient. We describe the epidemiology of a multistate outbreak of an influenza A(H3N2) variant virus (H3N2v) first identified in 2011.
Methods. We identified laboratory-confirmed cases of H3N2v and used a standard case report form to characterize illness and exposures. We considered illness to result from person-to-person H3N2v transmission if swine contact was not identified within 4 days prior to illness onset.
Results. From 9 July to 7 September 2012, we identified 306 cases of H3N2v in 10 states. The median age of all patients was 7 years. Commonly reported signs and symptoms included fever (98%), cough (85%), and fatigue (83%). Sixteen patients (5.2%) were hospitalized, and 1 fatal case was identified. The majority of those infected reported agricultural fair attendance (93%) and/or contact with swine (95%) prior to illness. We identified 15 cases of possible person-to-person transmission of H3N2v. Viruses recovered from patients were 93%-100% identical and similar to viruses recovered from previous cases of H3N2v. All H3N2v viruses examined were susceptible to oseltamivir and zanamivir and resistant to adamantane antiviral medications.
Conclusions. In a large outbreak of variant influenza, the majority of infected persons reported exposures, suggesting that swine contact at an agricultural fair was a risk for H3N2v infection. We identified limited person-to-person H3N2v virus transmission, but found no evidence of efficient or sustained person-to-person transmission. Fair managers and attendees should be aware of the risk of swine-to-human transmission of influenza viruses in these settings.
C1 [Jhung, Michael A.; Epperson, Scott; Biggerstaff, Matthew; Balish, Amanda; Barnes, Nathelia; Berman, LaShondra; Blanton, Lenee; Brammer, Lynnette; D'Mello, Tiffany; Davis, William; Emery, Shannon; Garten, Rebecca; Gubareva, Larisa; Jiang, Victoria; Jain, Seema; Jernigan, Daniel; Klimov, Alexander; Lindstrom, Stephen; McMorrow, Meredith; Reed, Carrie; Shu, Bo; Steffens, Craig; Su, Su; Uyeki, Timothy M.; Villanueva, Julie; Shaw, Michael; Bresee, Joseph S.; Cox, Nancy; Finelli, Lyn] Ctr Dis Control & Prevent, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
[Durand, Lizette O.; Greenbaum, Adena; Havers, Fiona; Wong, Karen K.] Ctr Dis Control & Prevent, Epidem Intelligence Serv, Influenza Div, Atlanta, GA 30333 USA.
[Quinn, Celia] Ohio Dept Hlth, Epidem Intelligence Serv, Columbus, OH 43266 USA.
[Lucas, Paul; Soyemi, Kenneth] Illinois Dept Publ Hlth, Springfield, IL 62761 USA.
[Grant, Yoran] Illinois Dept Publ Hlth, Epidem Intelligence Serv, Springfield, IL 62761 USA.
[Bidol, Sally; Peters, Susan] Michigan Dept Community Hlth, Lansing, MI USA.
[Danila, Richard; Lynfield, Ruth; Morin, Craig; Scheftel, Joni; Vetter, Sara] Minnesota Dept Hlth, St Paul, MN USA.
[Allen, Donna; House, Jennifer; Richards, Shawn; Stauffer, Jill] Indiana State Dept Hlth, Indianapolis, IN 46202 USA.
[Balish, Amanda] Penn Dept Hlth, Epidem Intelligence Serv, Harrisburg, PA 17108 USA.
[Longenberger, Allison; Moll, Maria; Ostroff, Stephen; Simwale, Owen; Torso, Lauren] Penn Dept Hlth, Harrisburg, PA 17108 USA.
[Park, Sarah Y.] Hawaii Dept Hlth, Honolulu, HI USA.
[de Fijter, Sietske; DiOrio, Mary; Fowler, Brian; Page, Shannon L.] Ohio Dept Hlth, Columbus, OH 43266 USA.
[Haupt, Thomas; Kazmierczak, James] Wisconsin Dept Hlth Serv, Madison, WI USA.
[Ibrahim, Sherif] West Virginia Bur Publ Hlth, Charleston, SC USA.
[Blythe, David] Maryland Dept Hlth & Mental Hyg, Baltimore, MD USA.
RP Jhung, MA (reprint author), Ctr Dis Control & Prevent, Influenza Div, 1600 Clifton Rd NE,MS A-32, Atlanta, GA 30333 USA.
EM mjhung@cdc.gov
NR 56
TC 59
Z9 60
U1 3
U2 17
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1058-4838
EI 1537-6591
J9 CLIN INFECT DIS
JI Clin. Infect. Dis.
PD DEC 15
PY 2013
VL 57
IS 12
BP 1703
EP 1712
DI 10.1093/cid/cit649
PG 10
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 262FT
UT WOS:000327720400008
PM 24065322
ER
PT J
AU Magill, SS
Klompas, M
Balk, R
Burns, SM
Deutschman, CS
Diekema, D
Fridkin, S
Greene, L
Guh, A
Gutterman, D
Hammer, B
Henderson, D
Hess, D
Hill, NS
Horan, T
Kollef, M
Levy, M
Septimus, E
VanAntwerpen, C
Wright, D
Lipsett, P
AF Magill, Shelley S.
Klompas, Michael
Balk, Robert
Burns, Suzanne M.
Deutschman, Clifford S.
Diekema, Daniel
Fridkin, Scott
Greene, Linda
Guh, Alice
Gutterman, David
Hammer, Beth
Henderson, David
Hess, Dean
Hill, Nicholas S.
Horan, Teresa
Kollef, Marin
Levy, Mitchell
Septimus, Edward
VanAntwerpen, Carole
Wright, Don
Lipsett, Pamela
TI Developing a New, National Approach to Surveillance for
Ventilator-Associated Events: Executive Summary
SO CLINICAL INFECTIOUS DISEASES
LA English
DT Editorial Material
DE ventilator-associated pneumonia; intensive care unit; epidemiology;
public health; critical care; mechanical ventilation
C1 [Magill, Shelley S.; Fridkin, Scott; Guh, Alice; Horan, Teresa] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA 30329 USA.
[Klompas, Michael] Harvard Univ, Sch Med, Dept Populat Med, Boston, MA USA.
[Klompas, Michael] Harvard Pilgrim Hlth Care Inst, Boston, MA USA.
[Klompas, Michael] Brigham & Womens Hosp, Infect Control Dept, Boston, MA 02115 USA.
[Klompas, Michael] Soc Healthcare Epidemiol Amer, Arlington, VA USA.
[Balk, Robert] Rush Univ, Sch Med, Div Pulm & Crit Care Med, Chicago, IL 60612 USA.
[Balk, Robert; Burns, Suzanne M.; Deutschman, Clifford S.; Gutterman, David; Hammer, Beth; Hill, Nicholas S.; Kollef, Marin; Levy, Mitchell; Lipsett, Pamela] Crit Care Soc Collaborat Amer Assoc Crit Care Nur, Charlottesville, VA USA.
[Burns, Suzanne M.] Univ Virginia, Sch Nursing Crit & Acute Care, Charlottesville, VA USA.
[Deutschman, Clifford S.] Univ Penn, Perelman Sch Med, Dept Anesthesiol & Crit Care, Philadelphia, PA 19104 USA.
[Diekema, Daniel] Univ Iowa, Carver Coll Med, Div Infect Dis, Iowa City, IA USA.
[Diekema, Daniel] Healthcare Infect Control Practices Advisory Comm, Atlanta, GA USA.
[Greene, Linda] Rochester Gen Hlth Syst, Infect Prevent & Control Dept, Rochester, NY USA.
[Greene, Linda] Assoc Profess Infect Control & Epidemiol, Washington, DC USA.
[Gutterman, David] Med Coll Wisconsin, Dept Med, Milwaukee, WI 53226 USA.
[Hammer, Beth] Zablocki VA Med Ctr, Dept Cardiol, Milwaukee, WI USA.
[Henderson, David] NIH, Hosp Epidemiol & Qual Improvement, Ctr Clin, Bethesda, MD 20892 USA.
[Hess, Dean] Massachusetts Gen Hosp, Dept Resp Care, Boston, MA 02114 USA.
[Hess, Dean] Harvard Univ, Sch Med, Dept Anesthesia, Boston, MA 02115 USA.
[Hess, Dean] Amer Assoc Resp Care, Irving, TX USA.
[Hill, Nicholas S.] Tufts Med Ctr, Div Pulm & Crit Care Med, Boston, MA USA.
[Kollef, Marin] Washington Univ, Div Pulm & Crit Care Med, St Louis, MO USA.
[Levy, Mitchell] Brown Univ, Rhode Isl Hosp, Warren Alpert Med Sch, Div Pulm Crit Care & Sleep, Providence, RI 02903 USA.
[Septimus, Edward] Texas A&M Hlth Sci Ctr, Dept Internal Med, College Stn, TX USA.
[Septimus, Edward] Infect Dis Soc Amer, Arlington, VA USA.
[VanAntwerpen, Carole] New York State Dept Hlth, Bur Healthcare Associated Infect, Albany, NY USA.
[VanAntwerpen, Carole] Council State & Terr Epidemiologists, Atlanta, GA USA.
[Wright, Don] US Dept HHS, Off Dis Prevent & Hlth Promot, Washington, DC 20201 USA.
[Lipsett, Pamela] Johns Hopkins Univ, Sch Med, Dept Surg Anesthesiol & Crit Care Med, Baltimore, MD USA.
RP Magill, SS (reprint author), Ctr Dis Control & Prevent, Div Healthcare Qual Promot, 1600 Clifton Rd,MS A-24, Atlanta, GA 30329 USA.
EM smagill@cdc.gov
NR 2
TC 12
Z9 13
U1 1
U2 4
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1058-4838
EI 1537-6591
J9 CLIN INFECT DIS
JI Clin. Infect. Dis.
PD DEC 15
PY 2013
VL 57
IS 12
BP 1742
EP 1746
DI 10.1093/cid/cit577
PG 5
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 262FT
UT WOS:000327720400013
PM 24280662
ER
PT J
AU Wang, LM
Kourtis, AP
Ellington, S
Legardy-Williams, J
Bulterys, M
AF Wang, Liming
Kourtis, Athena P.
Ellington, Sascha
Legardy-Williams, Jennifer
Bulterys, Marc
TI Safety of Tenofovir During Pregnancy for the Mother and Fetus: A
Systematic Review
SO CLINICAL INFECTIOUS DISEASES
LA English
DT Review
DE HIV; PMTCT; TDF; pregnancy; safety
ID HEPATITIS-B-VIRUS; SINGLE-DOSE TENOFOVIR; TO-CHILD TRANSMISSION;
REVERSE-TRANSCRIPTASE INHIBITORS; PREVENT PERINATAL TRANSMISSION;
EXPOSED UNINFECTED INFANTS; DISOPROXIL FUMARATE; MITOCHONDRIAL TOXICITY;
PREEXPOSURE PROPHYLAXIS; VERTICAL TRANSMISSION
AB Tenofovir disoproxil fumarate (TDF) safety during pregnancy has important public health implications. This review summarizes TDF safety during pregnancy, focusing on pregnancy outcomes, congenital anomaly risk, and other potential toxicities on neonates. Although information is limited, TDF appears to be safe during pregnancy. In 6 studies of human immunodeficiency virus type 1 (and/or hepatitis B virus)-infected women receiving TDF during pregnancy, adverse events were mild to moderate; none were considered to be TDF-related. Five studies that followed in utero TDF-exposed infants showed no increased risk of growth or bone abnormalities. One study showed slightly lower infant height at age 1 year, but the significance is unclear. The Antiretroviral Pregnancy Registry database, with 1800 pregnancies exposed to TDF in the first trimester, does not indicate increased congenital anomaly risk with TDF exposure. More evidence collected prospectively, ideally with bone density measurements and randomized trial design, will be optimal to determine the effects of antenatal TDF exposure on children's health.
C1 [Wang, Liming; Bulterys, Marc] US Ctr Dis Control & Prevent, Global AIDS Program, Beijing, Peoples R China.
[Kourtis, Athena P.; Ellington, Sascha; Legardy-Williams, Jennifer] US Ctr Dis Control & Prevent, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA.
[Bulterys, Marc] US Ctr Dis Control & Prevent, Div Global HIV AIDS, Ctr Global Hlth, Atlanta, GA USA.
RP Kourtis, AP (reprint author), Ctr Dis Control & Prevent, Womens Hlth & Fertil Branch, Div Reprod Hlth, 4770 Buford Hwy NE,MS K34, Atlanta, GA 30341 USA.
EM apk3@cdc.gov
NR 57
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PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1058-4838
EI 1537-6591
J9 CLIN INFECT DIS
JI Clin. Infect. Dis.
PD DEC 15
PY 2013
VL 57
IS 12
BP 1773
EP 1781
DI 10.1093/cid/cit601
PG 9
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 262FT
UT WOS:000327720400019
PM 24046310
ER
PT J
AU Breiman, RF
Van Beneden, CA
Farnon, EC
AF Breiman, Robert F.
Van Beneden, Chris A.
Farnon, Eileen C.
TI Surveillance for Respiratory Infections in Low- and Middle-Income
Countries: Experience From the Centers for Disease Control and
Prevention's Global Disease Detection International Emerging Infections
Program
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article
DE respiratory infections; surveillance; International Emerging Infections
Program
ID INFLUENZA-A H1N1; PNEUMONIA; THAILAND; ILLNESS; BURDEN; KENYA;
CORONAVIRUS; BANGLADESH; PATHOGENS; CHILDREN
C1 [Breiman, Robert F.] US Ctr Dis Control & Prevent, Kenya Off, Global Dis Detect Reg Ctr, Nairobi, Kenya.
[Van Beneden, Chris A.] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Resp Dis Branch, Div Bacterial Dis, Atlanta, GA 30333 USA.
[Farnon, Eileen C.] Ctr Dis Control & Prevent, Global Dis Detect Branch, Div Global Hlth Protect, Ctr Global Hlth, Atlanta, GA 30333 USA.
RP Farnon, EC (reprint author), Ctr Dis Control & Prevent, Global Dis Detect Branch, DGHP CGH, 1600 Clifton Rd NE,MS D-68, Atlanta, GA 30333 USA.
EM efarnon@cdc.gov
FU Global Disease Detection Program, Centers for Global Health; Influenza
Division, National Centers for Immunization and Respiratory Disease at
the US Centers for Disease Control and Prevention
FX This work was supported by the Global Disease Detection Program, Centers
for Global Health, and the Influenza Division, National Centers for
Immunization and Respiratory Disease at the US Centers for Disease
Control and Prevention.
NR 30
TC 3
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U1 0
U2 8
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0022-1899
EI 1537-6613
J9 J INFECT DIS
JI J. Infect. Dis.
PD DEC 15
PY 2013
VL 208
SU 3
BP S167
EP S172
DI 10.1093/infdis/jit462
PG 6
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 259RV
UT WOS:000327544900002
PM 24265474
ER
PT J
AU Fields, BS
House, BL
Klena, J
Waboci, LW
Whistler, T
Farnon, EC
AF Fields, Barry S.
House, Brent L.
Klena, John
Waboci, Lilian W.
Whistler, Toni
Farnon, Eileen C.
TI Role of Global Disease Detection Laboratories in Investigations of Acute
Respiratory Illness
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article
DE respiratory infections; laboratory; International Emerging Infections
Program
ID PATHOGENS
C1 [Fields, Barry S.; Waboci, Lilian W.] Ctr Dis Control & Prevent, Div Global Hlth Protect, Nairobi, Kenya.
[House, Brent L.] Naval Med Res, Unit 3, Global Dis Detect & Response Program, Cairo, Egypt.
[Klena, John] Ctr Dis Control & Prevent, Div Global Hlth Protect, Beijing, Peoples R China.
[Whistler, Toni] Ctr Dis Control & Prevent, Div Global Hlth Protect, Bangkok, Thailand.
[Farnon, Eileen C.] Ctr Dis Control & Prevent, Ctr Global Hlth, Global Dis Detect Branch, Div Global Hlth Protect, Atlanta, GA 30333 USA.
RP Farnon, EC (reprint author), Ctr Dis Control & Prevent, Sci Team, Global Dis Detect Branch, DGHP CGH, 1600 Clifton Rd NE,MS D-68, Atlanta, GA 30333 USA.
EM efarnon@cdc.gov
FU Global Disease Detection Program, Center for Global Health; Influenza
Division, National Center for Immunization and Respiratory Disease,
Centers for Disease Control and Prevention
FX This work was supported by the Global Disease Detection Program, Center
for Global Health, and by the Influenza Division, National Center for
Immunization and Respiratory Disease, Centers for Disease Control and
Prevention.
NR 10
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U1 0
U2 3
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0022-1899
EI 1537-6613
J9 J INFECT DIS
JI J. Infect. Dis.
PD DEC 15
PY 2013
VL 208
SU 3
BP S173
EP S176
DI 10.1093/infdis/jit490
PG 4
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 259RV
UT WOS:000327544900003
PM 24265475
ER
PT J
AU Haynes, AK
Manangan, AP
Iwane, MK
Sturm-Ramirez, K
Homaira, N
Brooks, WA
Luby, S
Rahman, M
Klena, JD
Zhang, YZ
Yu, HG
Zhan, FX
Dueger, E
Mansour, AM
Azazzy, N
McCracken, JP
Bryan, JP
Lopez, MR
Burton, DC
Bigogo, G
Breiman, RF
Feikin, DR
Njenga, K
Montgomery, J
Cohen, AL
Moyes, J
Pretorius, M
Cohen, C
Venter, M
Chittaganpitch, M
Thamthitiwat, S
Sawatwong, P
Baggett, HC
Luber, G
Gerber, SI
AF Haynes, Amber K.
Manangan, Arie P.
Iwane, Marika K.
Sturm-Ramirez, Katharine
Homaira, Nusrat
Brooks, W. Abdullah
Luby, Stephen
Rahman, Mahmudur
Klena, John D.
Zhang, Yuzhi
Yu, Hongie
Zhan, Faxian
Dueger, Erica
Mansour, Adel Mahmoud
Azazzy, Nahed
McCracken, John P.
Bryan, Joe P.
Lopez, Maria R.
Burton, Deron C.
Bigogo, Godfrey
Breiman, Robert F.
Feikin, Daniel R.
Njenga, Kariuki
Montgomery, Joel
Cohen, Adam L.
Moyes, Jocelyn
Pretorius, Marthi
Cohen, Cheryl
Venter, Marietjie
Chittaganpitch, Malinee
Thamthitiwat, Somsak
Sawatwong, Pongpun
Baggett, Henry C.
Luber, George
Gerber, Susan I.
TI Respiratory Syncytial Virus Circulation in Seven Countries With Global
Disease Detection Regional Centers
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article
DE respiratory tract infections; respiratory syncytial virus infections;
climate; seasons; humans
ID INFECTIONS; SEASONALITY; DYNAMICS; CLIMATE; TROPICS
AB Background. Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections in young children globally, with the highest burden in low-and middle-income countries where the association between RSV activity and climate remains unclear.
Methods. Monthly laboratory-confirmed RSV cases and associations with climate data were assessed for respiratory surveillance sites in tropical and subtropical areas (Bangladesh, China, Egypt, Guatemala, Kenya, South Africa, and Thailand) during 2004-2012. Average monthly minimum and maximum temperatures, relative humidity, and precipitation were calculated using daily local weather data from the US National Climatic Data Center.
Results. RSV circulated with 1-2 epidemic periods each year in site areas. RSV seasonal timing and duration were generally consistent within country from year to year. Associations between RSV and weather varied across years and geographic locations. RSV usually peaked in climates with high annual precipitation (Bangladesh, Guatemala, and Thailand) during wet months, whereas RSV peaked during cooler months in moderately hot (China) and arid (Egypt) regions. In South Africa, RSV peaked in autumn, whereas no associations with seasonal weather trends were observed in Kenya.
Conclusions. Further understanding of RSV seasonality in developing countries and various climate regions will be important to better understand the epidemiology of RSV and for timing the use of future RSV vaccines and immunoprophylaxis in low- and middle-income countries.
C1 [Haynes, Amber K.; Iwane, Marika K.; Montgomery, Joel] Johns Hopkins Univ, Natl Ctr Immunizat & Resp Dis, Div Viral Dis, Baltimore, MD USA.
[Manangan, Arie P.; Cohen, Adam L.; Luber, George] Johns Hopkins Univ, Natl Ctr Environm Hlth, Div Environm Hazards & Hlth Effects, Baltimore, MD USA.
[Sturm-Ramirez, Katharine; Montgomery, Joel] Johns Hopkins Univ, Natl Ctr Immunizat & Resp Dis, Influenza Div, Baltimore, MD USA.
[Sturm-Ramirez, Katharine; Homaira, Nusrat; Brooks, W. Abdullah; Luby, Stephen] Johns Hopkins Univ, Int Ctr Diarrhoeal Dis Res Bangladesh, Ctr Communicable Dis, Baltimore, MD USA.
[Brooks, W. Abdullah] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Int Hlth, Baltimore, MD USA.
[Rahman, Mahmudur] Inst Epidemiol Dis Control & Res, Dhaka, Bangladesh.
[Klena, John D.] Global Dis Detect Ctr, Beijing, Peoples R China.
[Zhang, Yuzhi] Hubei Prov Ctr Dis Control, Div HIV AIDS, Wuhan, Hubei, Peoples R China.
[Yu, Hongie; Dueger, Erica] Naval Med Res Unit 3, Global Dis Detect & Response Program, Cairo, Egypt.
[Mansour, Adel Mahmoud] Naval Med Res Unit 3, Bacterial & Parasit Dis Res Program, Div Bacterial Dis, Cairo, Egypt.
[Azazzy, Nahed] Minist Hlth & Populat, Int Emerging Infect Program, Cairo, Egypt.
[McCracken, John P.; Bryan, Joe P.; Lopez, Maria R.] Univ Valle Guatemala, Ctr Hlth Studies, Guatemala City, Guatemala.
[Bigogo, Godfrey; Njenga, Kariuki] Kenya Govt Med Res Ctr, Ctr Global Hlth Res, Nairobi, Kenya.
Ctr Dis Control & Prevent, Hlth Off 1, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA.
[Cohen, Adam L.] Ctr Dis Control & Prevent, Influenza Program, Johannesburg, South Africa.
[Moyes, Jocelyn; Pretorius, Marthi; Cohen, Cheryl; Venter, Marietjie] Natl Hlth Lab Serv, Natl Inst Communicable Dis, Johannesburg, South Africa.
[Venter, Marietjie] Univ Pretoria, Dept Med Virol, ZA-0001 Pretoria, South Africa.
[Chittaganpitch, Malinee] MOPH, Natl Inst Hlth, Nonthaburi, Thailand.
RP Haynes, AK (reprint author), Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, 1600 Clifton Rd NE,MS A-34, Atlanta, GA 30333 USA.
EM ahaynes1@cdc.gov
RI Venter, Marietjie/P-9604-2016;
OI Venter, Marietjie/0000-0003-2696-824X; Luby, Stephen/0000-0001-5385-899X
FU Centers for Disease Control and Prevention; Center for Global Health;
Division of Global Health Protection; National Center for Immunization
and Respiratory Diseases, Influenza Division
FX This work was supported by the Centers for Disease Control and
Prevention, Center for Global Health, Division of Global Health
Protection and the National Center for Immunization and Respiratory
Diseases, Influenza Division.
NR 32
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PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0022-1899
EI 1537-6613
J9 J INFECT DIS
JI J. Infect. Dis.
PD DEC 15
PY 2013
VL 208
SU 3
BP S246
EP S254
DI 10.1093/infdis/jit515
PG 9
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 259RV
UT WOS:000327544900012
PM 24265484
ER
PT J
AU Haynes, LM
AF Haynes, Lia M.
TI Progress and Challenges in RSV Prophylaxis and Vaccine Development
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article
ID RESPIRATORY SYNCYTIAL VIRUS; YOUNG-CHILDREN; MONOCLONAL-ANTIBODY;
EPITHELIAL-CELLS; G-PROTEIN; INFECTION; INFANTS; FUSION; CANDIDATE;
IMMUNOGENICITY
C1 [Haynes, Lia M.] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Viral Dis, Atlanta, GA 30333 USA.
RP Haynes, LM (reprint author), Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, 1600 Clifton Rd NE,A-34, Atlanta, GA 30333 USA.
EM loh5@cdc.gov
NR 54
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U1 0
U2 5
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0022-1899
EI 1537-6613
J9 J INFECT DIS
JI J. Infect. Dis.
PD DEC 15
PY 2013
VL 208
SU 3
BP S177
EP S183
DI 10.1093/infdis/jit512
PG 7
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 259RV
UT WOS:000327544900004
PM 24265476
ER
PT J
AU Huo, XX
Fang, B
Liu, LL
Yu, HJ
Chen, H
Zheng, JD
Zhang, YZ
Xu, Z
Klena, JD
Varma, JK
Peng, ZB
Xing, XS
Xuhua, G
Zhan, FX
AF Huo, Xixiang
Fang, Bin
Liu, Linlin
Yu, Hongjie
Chen, Hui
Zheng, Jiandong
Zhang, Yuzhi
Xu, Zhen
Klena, John D.
Varma, Jay K.
Peng, Zhibin
Xing, Xuesen
Xuhua, Guan
Zhan, Faxian
TI Clinical and Epidemiologic Characteristics of Respiratory Syncytial
Virus Infection Among Children Aged < 5 Years, Jingzhou City, China,
2011
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article
DE RSV; seasonal distribution; Hubei
ID TRACT INFECTIONS; DISEASE
AB Severe acute respiratory illness (SARI) surveillance began in Jingzhou City, China, in 2010. A subset of 511 children aged <5 years enrolled in the SARI study during 2011 were tested for influenza and noninfluenza respiratory viral infection by real-time reverse-transcription polymerase chain reaction. Respiratory syncytial virus (RSV) was most commonly detected. Children aged 12-23 and 24-60 months were equally likely to test positive for RSV. Although cases of RSV infection could be detected throughout the year, the greatest numbers were detected from autumn to early winter.
C1 [Huo, Xixiang; Fang, Bin; Liu, Linlin; Chen, Hui; Xing, Xuesen; Xuhua, Guan; Zhan, Faxian] Hubei Prov Dis Prevent & Control Ctr, Wuhan, Peoples R China.
[Yu, Hongjie; Zheng, Jiandong; Xu, Zhen; Peng, Zhibin] Ctr Dis Control & Prevent, Beijing, Peoples R China.
[Zhang, Yuzhi; Klena, John D.; Varma, Jay K.] Ctr Dis Control & Prevent, Atlanta, GA USA.
RP Klena, JD (reprint author), Ctr Dis Control & Prevent, Emerging Infect Program, China Off, Sect 7300 Box 060, DPO, AP 96521 USA.
EM irc4@cn.cdc.gov
FU Division of Global Disease Detection and Emergency Response; Center for
Global Health; Centers for Disease Control and Prevention
FX This work was supported by the Division of Global Disease Detection and
Emergency Response, Center for Global Health, Centers for Disease
Control and Prevention.
NR 15
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U2 6
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0022-1899
EI 1537-6613
J9 J INFECT DIS
JI J. Infect. Dis.
PD DEC 15
PY 2013
VL 208
SU 3
BP S184
EP S188
DI 10.1093/infdis/jit518
PG 5
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 259RV
UT WOS:000327544900005
PM 24265477
ER
PT J
AU Iwane, MK
Farnon, EC
Gerber, SI
AF Iwane, Marika K.
Farnon, Eileen C.
Gerber, Susan I.
TI Importance of Global Surveillance for Respiratory Syncytial Virus
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Editorial Material
DE respiratory syncytial virus; respiratory infections; international
ID INFECTION; ADULTS
C1 [Iwane, Marika K.; Gerber, Susan I.] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Viral Dis, Atlanta, GA 30333 USA.
[Farnon, Eileen C.] Ctr Dis Control & Prevent, Ctr Global Hlth, Div Global Hlth Protect, Atlanta, GA 30333 USA.
RP Iwane, MK (reprint author), Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, 1600 Clifton Rd,NE,MS A-34, Atlanta, GA 30333 USA.
EM miwane@cdc.gov
NR 5
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U1 0
U2 0
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0022-1899
EI 1537-6613
J9 J INFECT DIS
JI J. Infect. Dis.
PD DEC 15
PY 2013
VL 208
SU 3
BP S165
EP S166
DI 10.1093/infdis/jit484
PG 2
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 259RV
UT WOS:000327544900001
PM 24265473
ER
PT J
AU McCracken, JP
Prill, MM
Arvelo, W
Lindblade, KA
Lopez, MR
Estevez, A
Muller, ML
Munoz, F
Bernart, C
Cortez, M
Moir, JC
Ortiz, J
Paredes, A
Iwane, MK
AF McCracken, John P.
Prill, Mila M.
Arvelo, Wences
Lindblade, Kim A.
Lopez, Maria R.
Estevez, Alejandra
Muller, Maria L.
Munoz, Fredy
Bernart, Christopher
Cortez, Margarita
Moir, Juan C.
Ortiz, Jose
Paredes, Antonio
Iwane, Marika K.
TI Respiratory Syncytial Virus Infection in Guatemala, 2007-2012
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article
DE acute respiratory illness; epidemiology; respiratory syncytial virus;
severity; surveillance
ID HIGH-RISK ADULTS; YOUNG-CHILDREN; INFLUENZA-VIRUS; OLDER-ADULTS;
PNEUMONIA; BURDEN; BRONCHIOLITIS; POPULATION; DISEASE; HOSPITALIZATIONS
AB Background. Respiratory syncytial virus (RSV) is a major cause of acute respiratory illness (ARI). Little is known about RSV disease among older children and adults in Central America.
Methods. Prospective surveillance for ARI among hospital patients and clinic patients was conducted in Guatemala during 2007-2012. Nasopharyngeal and oropharyngeal swab specimens were tested for RSV, using real-time reverse-transcription polymerase chain reaction.
Results. Of 6287 hospitalizations and 2565 clinic visits for ARI, 24% and 12%, respectively, yielded RSV-positive test results. The incidence of RSV-positive hospitalization for ARI was 5.8 cases/10 000 persons per year and was highest among infants aged <6 months (208 cases/10 000 persons per year); among adults, the greatest incidence was observed among those aged >= 65 years (2.9 cases/10 000 persons per year). The incidence of RSV-positive clinic visitation for ARI was 32 cases/10 000 persons per year and was highest among infants aged 6-23 months (186 cases/10 000 persons per year). Among RSV-positive hospital patients with ARI, underlying cardiovascular disease was associated with death, moribund discharge, intensive care unit admission, or mechanical ventilation (odds ratio, 4.1; 95% confidence interval, 1.9-8.8). The case-fatality proportion among RSV-positive hospital patients with ARI was higher for those aged >= 5 years than for those aged <5 years (13% vs 3%; P < .001).
Conclusions. The incidences of RSV-associated hospitalization and clinic visitation for ARI were highest among young children, but a substantial burden of ARI due to RSV was observed among older children and adults.
C1 [McCracken, John P.; Lopez, Maria R.; Estevez, Alejandra; Muller, Maria L.; Munoz, Fredy; Bernart, Christopher] Univ Valle Guatemala, Ctr Hlth Studies, Guatemala City, Guatemala.
[Cortez, Margarita; Moir, Juan C.; Paredes, Antonio] Minist Publ Hlth & Social Welf, Guatemala City, Guatemala.
[Ortiz, Jose] Guatemalan Social Secur Inst, Guatemala City, Guatemala.
[Prill, Mila M.; Iwane, Marika K.] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Viral Dis, Atlanta, GA USA.
[Arvelo, Wences; Lindblade, Kim A.] Ctr Dis Control & Prevent, Div Global Dis Detect & Emergency Response, Atlanta, GA USA.
RP McCracken, JP (reprint author), Univ Valle Guatemala, Ctr Hlth Studies, 18 Ave 11-95,Zona 15,VH 3, Guatemala City, Guatemala.
EM jmccracken@ces.uvg.edu.gt
FU Centers for Disease Control's Global Disease Detection and Emerging
Infections; Universidad del Valle de Guatemala [1U01GH000028-03]
FX This work was supported by the Centers for Disease Control's Global
Disease Detection and Emerging Infections appropriations through a
cooperative agreement with the Universidad del Valle de Guatemala
(1U01GH000028-03).
NR 33
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PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0022-1899
EI 1537-6613
J9 J INFECT DIS
JI J. Infect. Dis.
PD DEC 15
PY 2013
VL 208
SU 3
BP S197
EP S206
DI 10.1093/infdis/jit517
PG 10
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 259RV
UT WOS:000327544900007
PM 24265479
ER
PT J
AU Moyes, J
Cohen, C
Pretorius, M
Groome, M
von Gottberg, A
Wolter, N
Walaza, S
Haffejee, S
Chhagan, M
Naby, F
Cohen, AL
Tempia, S
Kahn, K
Dawood, H
Venter, M
Madhi, SA
AF Moyes, Jocelyn
Cohen, Cheryl
Pretorius, Marthi
Groome, Michelle
von Gottberg, Anne
Wolter, Nicole
Walaza, Sibongile
Haffejee, Sumayya
Chhagan, Meera
Naby, Fathima
Cohen, Adam L.
Tempia, Stefano
Kahn, Kathleen
Dawood, Halima
Venter, Marietjie
Madhi, Shabir A.
CA South African Severe Acute Resp Il
TI Epidemiology of Respiratory Syncytial Virus-Associated Acute Lower
Respiratory Tract Infection Hospitalizations Among HIV-Infected and
HIV-Uninfected South African Children, 2010-2011
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article
ID SERIOUS BACTERIAL-INFECTIONS; INFANTS; BURDEN; RISK
AB Background. There are limited data on respiratory syncytial virus (RSV) infection among children in settings with a high prevalence of human immunodeficiency virus (HIV). We studied the epidemiology of RSV-associated acute lower respiratory tract infection (ALRTI) hospitalizations among HIV-infected and HIV-uninfected children in South Africa.
Methods. Children aged <5 years admitted to sentinel surveillance hospitals with physician-diagnosed neonatal sepsis or ALRTI were enrolled. Nasopharyngeal aspirates were tested by multiplex real-time polymerase chain reaction assays for RSV and other viruses. Associations between possible risk factors and severe outcomes for RSV infection among HIV-infected and uninfected children were examined. The relative risk of hospitalization in HIV-infected and HIV-uninfected children was calculated in 1 site with population denominators.
Results. Of 4489 participants, 4293 (96%) were tested for RSV, of whom 1157 (27%) tested positive. With adjustment for age, HIV-infected children had a 3-5-fold increased risk of hospitalization with RSV-associated ALRTI (2010 relative risk, 5.6; [95% confidence interval (CI), 4.5-6.4]; 2011 relative risk, 3.1 [ 95% CI, 2.6-3.6]). On multivariable analysis, HIV-infected children with RSV-associated ALRTI had higher odds of death (adjusted odds ratio. 31.1; 95% CI, 5.4-179.8) and hospitalization for >5 days (adjusted odds ratio, 4.0; 95% CI, 1.5-10.6) than HIV-uninfected children.
Conclusion. HIV-infected children have a higher risk of hospitalization with RSV-associated ALRTI and a poorer outcome than HIV-uninfected children. These children should be targeted for interventions aimed at preventing severe RSV disease.
C1 [Moyes, Jocelyn; Cohen, Cheryl; Pretorius, Marthi; von Gottberg, Anne; Wolter, Nicole; Walaza, Sibongile; Tempia, Stefano; Venter, Marietjie; Madhi, Shabir A.] Univ Witwatersrand, Natl Hlth Lab Serv, Natl Inst Communicable Dis, Ctr Resp Dis & Meningitis, Johannesburg, South Africa.
[Moyes, Jocelyn; Cohen, Cheryl] Univ Witwatersrand, Fac Hlth Sci, Sch Publ Hlth, Johannesburg, South Africa.
[Groome, Michelle; Madhi, Shabir A.] Univ Witwatersrand, Natl Res Fdn Vaccine Preventable Dis, Med Res Council, Resp & Meningeal Pathogens Res Unit, Johannesburg, South Africa.
[Groome, Michelle; Madhi, Shabir A.] Univ Witwatersrand, Natl Res Fdn Vaccine Preventable Dis, Dept Sci & Technol, Johannesburg, South Africa.
[Haffejee, Sumayya; Chhagan, Meera; Naby, Fathima; Dawood, Halima] Pietermaritzburg Hosp Complex, Pretoria, South Africa.
[Haffejee, Sumayya; Chhagan, Meera; Naby, Fathima; Dawood, Halima] Univ KwaZulu Natal, Pretoria, South Africa.
[Cohen, Adam L.; Tempia, Stefano] Ctr Dis Control & Prevent, Influenza Program, Pretoria, South Africa.
[Cohen, Adam L.; Tempia, Stefano] Ctr Dis Control & Prevent, Influenza Program, Atlanta, GA USA.
[Kahn, Kathleen] Umea Univ, S-90187 Umea, Sweden.
[Kahn, Kathleen] INDEPTH network, Accra, Ghana.
RP Moyes, J (reprint author), Natl Inst Communicable Dis, Ctr Resp Dis & Meningitis, Private Bag X4, ZA-2131 Johannesburg, Gauteng, South Africa.
EM jocelynm@nicd.ac.za
RI Venter, Marietjie/P-9604-2016;
OI Venter, Marietjie/0000-0003-2696-824X; Pretorius,
Marthi/0000-0003-2163-6158
FU Centers for Disease Control and Prevention [5U51IP000155, 1U51IP000528]
FX The Severe Acute Respiratory Illness surveillance program has been
funded through 2 grants from the Centers for Disease Control and
Prevention, namely, South African Preparedness for Rapid Detection of
Highly Pathogenic Avian Influenza (grant 5U51IP000155) and Sustaining
Surveillance Networks and Response to Seasonal Influenza (grant
1U51IP000528).
NR 25
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U1 1
U2 9
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0022-1899
EI 1537-6613
J9 J INFECT DIS
JI J. Infect. Dis.
PD DEC 15
PY 2013
VL 208
SU 3
BP S217
EP S226
DI 10.1093/infdis/jit479
PG 10
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 259RV
UT WOS:000327544900009
PM 24265481
ER
PT J
AU Naorat, S
Chittaganpitch, M
Thamthitiwat, S
Henchaichon, S
Sawatwong, P
Srisaengchai, P
Lu, Y
Chuananon, S
Amornintapichet, T
Chantra, S
Erdman, DD
Maloney, SA
Akarasewi, P
Baggett, HC
AF Naorat, Sathapana
Chittaganpitch, Malinee
Thamthitiwat, Somsak
Henchaichon, Sununta
Sawatwong, Pongpun
Srisaengchai, Prasong
Lu, Ying
Chuananon, Somchai
Amornintapichet, Tussanee
Chantra, Somrak
Erdman, Dean D.
Maloney, Susan A.
Akarasewi, Passakorn
Baggett, Henry C.
TI Hospitalizations for Acute Lower Respiratory Tract Infection Due to
Respiratory Syncytial Virus in Thailand, 2008-2011
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article
DE respiratory syncytial virus; acute lower respiratory infection; Thailand
ID RURAL THAILAND; PNEUMONIA; SURVEILLANCE
AB Background. Few population-based estimates of the incidence of respiratory syncytial virus (RSV) infection in low-or middle-income countries are available. We describe the incidence and epidemiology of hospitalizations for RSV-associated acute lower respiratory tract infection (ALRI) detected by active population-based surveillance in 2 rural Thailand provinces during 2008-2011.
Methods. Patients hospitalized with ALRI were systematically sampled. Consenting patients provided nasopharyngeal swab specimens for RSV testing by real-time reverse-transcription polymerase chain reaction.
Results. Of 13 982 enrolled patients hospitalized with ALRI, 1137 (8.1%) were RSV positive. After adjustment for sampling and nonenrollment, the incidence of RSV-associated ALRI hospitalization was 85 cases per 100 000 persons/year. The highest rates occurred among children aged <5 years (981 cases per 100 000 persons/year) and <1 year (1543 cases per 100 000 persons/year). Rates were low among older children and young adults but high among persons aged >65 years (130 cases per 100 000 persons/year). Eight (0.7%) RSV-infected study patients died during hospitalization. Annual RSV hospitalizations peaked during July-October with almost no documented RSV hospitalizations during January-June.
Conclusions. Our findings demonstrate the substantial contribution of RSV to global ALRI burden, especially in children aged <5 years and the elderly, and underscore the urgent need for effective prevention measures.
C1 [Naorat, Sathapana; Thamthitiwat, Somsak; Henchaichon, Sununta; Sawatwong, Pongpun; Srisaengchai, Prasong; Lu, Ying; Maloney, Susan A.; Baggett, Henry C.] Thailand Minist Publ Hlth MOPH, US Ctr Dis Control & Prevent Collaborat, Global Dis Detect Reg Ctr, Int Emerging Infect Program, Muang, Nothanburi, Thailand.
[Chittaganpitch, Malinee] MOPH, Natl Inst Hlth, Nonthaburi, Thailand.
[Akarasewi, Passakorn] MOPH, Bur Epidemiol, Nonthaburi, Thailand.
[Erdman, Dean D.] Ctr Dis Control & Prevent, Div Viral Dis, Atlanta, GA USA.
[Baggett, Henry C.] Ctr Dis Control & Prevent, Div Global Hlth Protect, Atlanta, GA USA.
RP Baggett, HC (reprint author), Minist Publ Hlth, Thailand MOPH US CDC Collaborat, Int Emerging Infect Program, DDC7 Bldg,3rd Fl,Soi 4,Tivanon Rd, Muang 11000, Nonthaburi, Thailand.
EM kipb@th.cdc.gov
FU Global Disease Detection Program of the US Centers for Disease Control
and Prevention
FX This work was supported by the Global Disease Detection Program of the
US Centers for Disease Control and Prevention.
NR 24
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U1 0
U2 3
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0022-1899
EI 1537-6613
J9 J INFECT DIS
JI J. Infect. Dis.
PD DEC 15
PY 2013
VL 208
SU 3
BP S238
EP S245
DI 10.1093/infdis/jit456
PG 8
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 259RV
UT WOS:000327544900011
PM 24265483
ER
PT J
AU Rowlinson, E
Dueger, E
Taylor, T
Mansour, A
Van Beneden, C
Abukela, M
Zhang, XY
Refaey, S
Bastawy, H
Kandeel, A
AF Rowlinson, Emily
Dueger, Erica
Taylor, Thomas
Mansour, Adel
Van Beneden, Chris
Abukela, Mohamed
Zhang, Xingyou
Refaey, Samir
Bastawy, Hesham
Kandeel, Amr
TI Incidence and Clinical Features of Respiratory Syncytial Virus
Infections in a Population-Based Surveillance Site in the Nile Delta
Region
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article
DE respiratory syncytial virus; incidence; population-based surveillance
ID YOUNG-CHILDREN; HOSPITALIZATIONS; BRONCHIOLITIS; BURDEN; RSV
AB Background. Most reports about respiratory syncytial virus (RSV) in developing countries rely on sentinel surveillance, from which population incidence is difficult to infer. We used the proportion of RSV infections from population-based surveillance with data from a healthcare utilization survey to produce estimates of RSV incidence in Damanhour district, Egypt.
Methods. We conducted population-based surveillance in 3 hospitals (2009-2012) and 3 outpatient clinics (2011-2012) in Damanhour district. Nasopharyngeal and oropharyngeal specimens from hospitalized patients with acute respiratory illness and outpatients with influenza-like illness were tested by real-time reverse transcriptase polymerase chain reaction for RSV. We also conducted a healthcare utilization survey in 2011-2012 to determine the proportion of individuals who sought care for respiratory illness.
Results. Among 5342 hospitalized patients and 771 outpatients, 12% and 5% tested positive for RSV, respectively. The incidence of RSV-associated hospitalization and outpatient visits was estimated at 24 and 608 (per 100 000 person-years), respectively. Children aged <1 year experienced the highest incidence of RSV-associated hospitalizations (1745/100 000 person-years).
Conclusions. This study demonstrates the utility of combining a healthcare utilization survey and population-based surveillance data to estimate disease incidence. Estimating incidence and outcomes of RSV disease is critical to establish the burden of RSV in Egypt.
C1 [Rowlinson, Emily; Dueger, Erica] US Naval Med Res Unit 3, Global Dis Detect & Response Program, Cairo, Egypt.
[Dueger, Erica] Ctr Dis Control & Prevent, Ctr Global Hlth, Div Global Hlth Protect, Atlanta, GA USA.
[Taylor, Thomas; Van Beneden, Chris] Ctr Dis Control & Prevent, Resp Dis Branch, Natl Ctr Immunizat & Resp Dis, Atlanta, GA USA.
[Mansour, Adel] Naval Med Res Unit 3, Bacterial & Parasit Dis Res Program, Div Bacterial Dis, Cairo, Egypt.
[Abukela, Mohamed] Minist Hlth & Populat, Int Emerging Infect Program, Cairo, Egypt.
[Zhang, Xingyou] Ctr Dis Control & Prevent, Div Populat Hlth, Atlanta, GA USA.
[Refaey, Samir; Bastawy, Hesham; Kandeel, Amr] Minist Hlth & Populat, Cairo, Egypt.
RP Rowlinson, E (reprint author), US Naval Med Res Unit 3, Global Dis Detect & Response Program, 1209 Payne Ave, Austin, TX 78757 USA.
EM emily.rowlinson@gmail.com
FU CDC; Armed Forces Health Surveillance Center's Global Emerging
Infections Surveillance Program
FX This work was supported by the CDC and the Armed Forces Health
Surveillance Center's Global Emerging Infections Surveillance Program.
NR 21
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U2 1
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0022-1899
EI 1537-6613
J9 J INFECT DIS
JI J. Infect. Dis.
PD DEC 15
PY 2013
VL 208
SU 3
BP S189
EP S196
DI 10.1093/infdis/jit457
PG 8
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 259RV
UT WOS:000327544900006
PM 24265478
ER
PT J
AU Smith, BD
Jewett, A
Burt, RD
Zibbell, JE
Yartel, AK
DiNenno, E
AF Smith, Bryce D.
Jewett, Amy
Burt, Richard D.
Zibbell, Jon E.
Yartel, Anthony K.
DiNenno, Elizabeth
TI "To Share or Not to Share?" Serosorting by Hepatitis C Status in the
Sharing of Drug Injection Equipment Among NHBS-IDU2 Participants
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article
DE hepatitis C virus; serosorting; injection drug use; sharing injection
equipment
ID VIRUS-INFECTION; HIV-INFECTION; RISK BEHAVIOR; UNITED-STATES; USERS;
PREVALENCE; SURVEILLANCE; POPULATION; MEN
AB Background. Persons who inject drugs (PWID) are at high risk for acquiring hepatitis C virus (HCV) infection. The Centers for Disease Control and Prevention estimates there are 17 000 new infections per year, mainly among PWID. This study examines injection equipment serosorting-considering HCV serostatus when deciding whether and with whom to share injection equipment.
Objective. To examine whether injection equipment serosorting is occurring among PWID in selected cities.
Methods. Using data from the National HIV Behavioral Surveillance System-Injection Drug Users (NHBS-IDU2, 2009), we developed multivariate logistic regression models to examine the extent to which participants' self-reported HCV status is associated with their injection equipment serosorting behavior and knowledge of last injecting partner's HCV status.
Results. Participants who knew their HCV status were more likely to know the HCV status of their last injecting partner, compared to those who did not know their status (HCV+: adjusted odds ratio [aOR] 4.1, 95% confidence interval [CI], 3.4-4.9; HCV-: aOR 2.5, 95% CI, 2.0-3.0). Participants who reported being HCV+, relative to those of unknown HCV status, were 5 times more likely to share injection equipment with a partner of HCV-positive status (aOR 4.8, 95% CI, 3.9-6.0).
Conclusions. Our analysis suggests PWID are more likely to share injection equipment with persons of concordant HCV status.
C1 [Smith, Bryce D.; Zibbell, Jon E.] Ctr Dis Control & Prevent, Div Viral Hepatitis, Atlanta, GA USA.
[Jewett, Amy] Oak Ridge Inst Sci & Educ, Oak Ridge, TN USA.
[Burt, Richard D.] Publ Hlth Seattle & King Cty, Seattle, WA USA.
[Yartel, Anthony K.] Ctr Dis Control & Prevent Fdn, Atlanta, GA USA.
[DiNenno, Elizabeth] Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA USA.
RP Smith, BD (reprint author), 1600 Clifton Rd,MS G-37, Atlanta, GA 30333 USA.
EM bsmith6@cdc.gov
OI Yartel, Anthony/0000-0001-6586-9362
FU Division of Viral Hepatitis at the Centers for Disease Control and
Prevention; Division of HIV/AIDS Prevention at the Centers for Disease
Control and Prevention
FX Funding for this study was provided by Divisions of Viral Hepatitis and
HIV/AIDS Prevention at the Centers for Disease Control and Prevention.
NR 37
TC 7
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U1 0
U2 2
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0022-1899
EI 1537-6613
J9 J INFECT DIS
JI J. Infect. Dis.
PD DEC 15
PY 2013
VL 208
IS 12
BP 1934
EP 1942
DI 10.1093/infdis/jit520
PG 9
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 259RS
UT WOS:000327544600003
PM 24136794
ER
PT J
AU Barskey, AE
Juieng, P
Whitaker, BL
Erdman, DD
Oberste, MS
Chern, SWW
Schmid, DS
Radford, KW
McNall, RJ
Rota, PA
Hickman, CJ
Bellini, WJ
Wallace, GS
AF Barskey, Albert E.
Juieng, Phalasy
Whitaker, Brett L.
Erdman, Dean D.
Oberste, M. Steven
Chern, Shur-Wern Wang
Schmid, D. Scott
Radford, Kay W.
McNall, Rebecca J.
Rota, Paul A.
Hickman, Carole J.
Bellini, William J.
Wallace, Gregory S.
TI Viruses Detected Among Sporadic Cases of Parotitis, United States,
2009-2011
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article
DE mumps; parotitis; diagnostics
ID REAL-TIME PCR; MUMPS OUTBREAK; VACCINE EFFECTIVENESS;
UNIVERSITY-STUDENTS; ENZYME-IMMUNOASSAY; PARA-INFLUENZA; INFECTIONS;
CHILDREN; RUBELLA; MEASLES
AB Background. Sporadic cases of parotitis are generally assumed to be mumps, which often requires a resource-intensive public health response. This project surveyed the frequency of viruses detected among such cases.
Methods. During 2009-2011, 8 jurisdictions throughout the United States investigated sporadic cases of parotitis. Epidemiologic information, serum, and buccal and oropharyngeal swabs were collected. Polymerase chain reaction methods were used to detect a panel of viruses. Anti-mumps virus immunoglobulin M (IgM) antibodies were detected using a variety of methods.
Results. Of 101 specimens, 38 were positive for a single virus: Epstein-Barr virus (23), human herpesvirus (HHV)-6B (10), human parainfluenza virus (HPIV)-2 (3), HPIV-3 (1), and human bocavirus (1). Mumps virus, enteroviruses (including human parechovirus), HHV-6A, HPIV-1, and adenoviruses were not detected. Early specimen collection did not improve viral detection rate. Mumps IgM was detected in 17% of available specimens. Patients in whom a virus was detected were younger, but no difference was seen by sex or vaccination profile. No seasonal patterns were identified.
Conclusions. Considering the timing of specimen collection, serology results, patient vaccination status, and time of year may be helpful in assessing the likelihood that a sporadic case of parotitis without laboratory confirmation is mumps.
C1 [Barskey, Albert E.; Whitaker, Brett L.; Erdman, Dean D.; Oberste, M. Steven; Chern, Shur-Wern Wang; Schmid, D. Scott; Radford, Kay W.; McNall, Rebecca J.; Rota, Paul A.; Hickman, Carole J.; Bellini, William J.; Wallace, Gregory S.] Natl Ctr Immunizat & Resp Dis, Div Viral Dis, Atlanta, GA USA.
[Juieng, Phalasy] Ctr Dis Control & Prevent, Natl Ctr Emerging & Zoonot Infect Dis, Div Sci Resources, Atlanta, GA 30333 USA.
RP Barskey, AE (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd NE,MS E-47, Atlanta, GA 30333 USA.
EM abarskey@cdc.gov
FU public health surveillance by the CDC
FX This work was supported as public health surveillance by the CDC.
NR 47
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U1 0
U2 3
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0022-1899
EI 1537-6613
J9 J INFECT DIS
JI J. Infect. Dis.
PD DEC 15
PY 2013
VL 208
IS 12
BP 1979
EP 1986
DI 10.1093/infdis/jit408
PG 8
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 259RS
UT WOS:000327544600008
PM 23935203
ER
PT J
AU Ursem, C
Fleming, ST
Sabatino, S
Wu, XC
Wilson, JF
Lipscomb, J
Cress, R
Anderson, R
Kimmick, G
AF Ursem, C.
Fleming, S. T.
Sabatino, S.
Wu, X-C
Wilson, J. F.
Lipscomb, J.
Cress, R.
Anderson, R.
Kimmick, G.
TI Does socioeconomic status (SES) influence receipt of guideline
concordant care in older women with breast cancer: Findings from a
Centers for Disease Control and Prevention national program of cancer
registries (NPCR) patterns of care study
SO CANCER RESEARCH
LA English
DT Meeting Abstract
C1 Duke Univ, Med Ctr, Durham, NC USA.
Univ Kentucky, Coll Publ Hlth, Lexington, KY USA.
Louisiana State Univ, Hlth Sci Ctr, New Orleans, LA USA.
Rollins Sch Publ Hlth, Atlanta, GA USA.
Ctr Dis Control & Prevent, Atlanta, GA USA.
Med Coll Wisconsin, Milwaukee, WI 53226 USA.
UC Davis Sch Med, Sacramento, CA USA.
Penn State Coll Med, Hershey, PA USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER ASSOC CANCER RESEARCH
PI PHILADELPHIA
PA 615 CHESTNUT ST, 17TH FLOOR, PHILADELPHIA, PA 19106-4404 USA
SN 0008-5472
EI 1538-7445
J9 CANCER RES
JI Cancer Res.
PD DEC 15
PY 2013
VL 73
SU 24
MA P1-09-05
DI 10.1158/0008-5472.SABCS13-P1-09-05
PG 2
WC Oncology
SC Oncology
GA V40RY
UT WOS:000209496900218
ER
PT J
AU Ogilvie, GS
Smith, LW
van Niekerk, DJ
Khurshed, F
Krajden, M
Saraiya, M
Goel, V
Rimer, BK
Greene, SB
Hobbs, S
Coldman, AJ
Franco, EL
AF Ogilvie, Gina S.
Smith, Laurie W.
van Niekerk, Dirk J.
Khurshed, Fareeza
Krajden, Mel
Saraiya, Mona
Goel, Vivek
Rimer, Barbara K.
Greene, Sandra B.
Hobbs, Suzanne
Coldman, Andrew J.
Franco, Eduardo L.
TI Women's intentions to receive cervical cancer screening with primary
human papillomavirus testing
SO INTERNATIONAL JOURNAL OF CANCER
LA English
DT Article
DE HPV; cervical cancer screening; intention; theory of planned behavior
ID RANDOMIZED CONTROLLED-TRIAL; LIQUID-BASED CYTOLOGY; INTRAEPITHELIAL
NEOPLASIA; CONVENTIONAL CYTOLOGY; PLANNED BEHAVIOR; FOLLOW-UP; HPV;
KNOWLEDGE; ATTITUDES; IMPACT
AB We explored the potential impact of human papillomavirus (HPV) testing on women's intentions to be screened for cervical cancer in a cohort of Canadian women. Participants aged 25-65 years from an ongoing trial were sent a questionnaire to assess women's intentions to be screened for cervical cancer with HPV testing instead of Pap smears and to be screened every 4 years or after 25 years of age. We created scales for attitudes about HPV testing, perceived behavioral control, and direct and indirect subjective norms. Demographic data and scales that were significantly different (p < 0.1) between women who intended to be screened with HPV and those who did not intend were included in a stepwise logistic regression model. Of the 2,016 invitations emailed, 1,538 were received, and 981 completed surveys for a response rate of 63% (981/1,538). Eighty-four percent of women (826/981) responded that they intended to attend for HPV-based cervical cancer screening, which decreased to 54.2% when the screening interval was extended, and decreased further to 51.4% when screening start was delayed to age of 25. Predictors of intentions to undergo screening were attitudes (odds ratio [OR]: 1.22; 95% confidence interval [CI]: 1.15, 1.30), indirect subjective norms (OR: 1.02; 95% CI: 1.01, 1.03) and perceived behavioral control (OR: 1.16; 95% CI: 1.10; 1.22). Intentions to be screened for cervical cancer with HPV testing decreased substantially when the screening interval was extended and screening started at age of 25. Use of primary HPV testing may optimize the screening paradigm, but programs should ensure robust planning and education to mitigate any negative impact on screening attendance rates.
C1 [Ogilvie, Gina S.; Krajden, Mel] Univ British Columbia, Dept Family Practice, Vancouver, BC V5Z 4R4, Canada.
[Ogilvie, Gina S.; Krajden, Mel] Univ British Columbia, Dept Pathol & Lab Med, Vancouver, BC V5Z 4R4, Canada.
[Ogilvie, Gina S.; Krajden, Mel] British Columbia Ctr Dis Control, Vancouver, BC V5Z 4R4, Canada.
[Smith, Laurie W.; van Niekerk, Dirk J.; Khurshed, Fareeza; Coldman, Andrew J.] British Columbia Canc Agcy, Vancouver, BC V5Z 4E6, Canada.
[Saraiya, Mona] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Goel, Vivek] Publ Hlth Ontario, Toronto, ON, Canada.
[Rimer, Barbara K.; Greene, Sandra B.; Hobbs, Suzanne] Univ N Carolina, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA.
[Franco, Eduardo L.] McGill Univ, Div Canc Epidemiol, Montreal, PQ, Canada.
RP Ogilvie, GS (reprint author), Univ British Columbia, 655 West 12th Ave, Vancouver, BC V5Z 4R4, Canada.
EM gina.ogilvie@bccdc.ca
OI Goel, Vivek/0000-0002-1389-2007; Franco, Eduardo/0000-0002-4409-8084
FU Canadian Foundation for Women's Health
FX Grant sponsor: The Canadian Foundation for Women's Health
NR 45
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U1 1
U2 41
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0020-7136
EI 1097-0215
J9 INT J CANCER
JI Int. J. Cancer
PD DEC 15
PY 2013
VL 133
IS 12
BP 2934
EP 2943
DI 10.1002/ijc.28324
PG 10
WC Oncology
SC Oncology
GA 233JW
UT WOS:000325565600018
PM 23754203
ER
PT J
AU McAfee, T
Davis, KC
Alexander, RL
Pechacek, TF
Bunnell, R
AF McAfee, Tim
Davis, Kevin C.
Alexander, Robert L., Jr.
Pechacek, Terry F.
Bunnell, Rebecca
TI Effect of the first federally funded US antismoking national media
campaign
SO LANCET
LA English
DT Article
ID SMOKING-CESSATION; UNITED-STATES; COST-EFFECTIVENESS; TOBACCO CAMPAIGN;
QUIT ATTEMPTS; INTERNET; SMOKERS; PREVALENCE; ABSTINENCE; ACCURACY
AB Background Every year, smoking kills more than 5 million people globally, including 440 000 people in the USA, where the long-term decline in smoking prevalence has slowed. The US Centers for Disease Control and Prevention (CDC) delivered a national, 3-month antismoking campaign called Tips From Former Smokers (Tips) that started in March, 2012, in which hard-hitting, emotionally evocative television advertising was featured, depicting smoking-related suffering in real people. We aimed to assess the effects of the Tips campaign.
Methods We undertook baseline and follow-up surveys of nationally representative cohorts of adult smokers and nonsmokers. The national effect of the Tips campaign was estimated by applying rates of change in the cohort before and after the campaign to US census data.
Findings 3051 smokers and 2220 non-smokers completed baseline and follow-up assessments. 2395 (78%) smokers and 1632 (74%) non-smokers recalled seeing at least one Tips advertisement on television during the 3-month campaign. Quit attempts among smokers rose from 31.1% (95% CI 30.3-31.9) at baseline to 34.8% (34.0-35.7) at follow-up, a 12% relative increase. The prevalence of abstinence at follow-up among smokers who made a quit attempt was 13.4% (95% CI 9.7-17.2). Nationally, an estimated 1.64 million additional smokers made a quit attempt, and 220 000 (95% CI 159 000-282 000) remained abstinent at follow-up. Recommendations by non-smokers to quit grew from 2.6% at baseline to 5.1% at follow-up, and the prevalence of people talking with friends and family about the dangers of smoking rose from 31.9% (95% CI 31.3-32.5) to 35.2% (34.6-35.9), resulting in an estimated 4.7 million additional non-smokers recommending cessation services and more than 6 million talking about the dangers of smoking.
Interpretation The high-exposure Tips media campaign was effective at increasing population-level quit attempts. The growth in smokers who quit and became sustained quitters could have added from a third to almost half a million quality-adjusted life-years to the US population. Expanded implementation of similar campaigns globally could accelerate progress on the WHO Framework Convention on Tobacco Control and reduce smoking prevalence globally.
C1 [McAfee, Tim; Alexander, Robert L., Jr.; Pechacek, Terry F.; Bunnell, Rebecca] Ctr Dis Control & Prevent, Off Smoking & Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30341 USA.
[Davis, Kevin C.] RTI Int, Res Triangle Pk, NC USA.
RP McAfee, T (reprint author), Ctr Dis Control & Prevent, Off Smoking & Hlth, Atlanta, GA 30341 USA.
EM mtt4@cdc.gov
FU CDC; US Department of Health and Human Services
FX Funding CDC, US Department of Health and Human Services.
NR 40
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U1 1
U2 19
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0140-6736
EI 1474-547X
J9 LANCET
JI Lancet
PD DEC 14
PY 2013
VL 382
IS 9909
BP 2003
EP 2011
DI 10.1016/S0140-6736(13)61686-4
PG 9
WC Medicine, General & Internal
SC General & Internal Medicine
GA 269EI
UT WOS:000328223700027
PM 24029166
ER
PT J
AU Ray, G
Schulz, T
Daniels, W
Daly, ER
Andrew, TA
Brown, CM
Cummings, P
Nelson, R
Cartter, ML
Backenson, PB
White, JL
Kurpiel, PM
Rockwell, R
Rotans, AS
Hertzog, C
Squires, LS
Linden, JV
Prial, M
House, J
Pontones, P
Batten, B
Blau, D
DeLeon-Carnes, M
Muehlenbachs, A
Ritter, J
Sanders, J
Zaki, SR
Mead, P
Hinckley, A
Nelson, C
Perea, A
Schriefer, M
Molins, C
Forrester, JD
AF Ray, Gregory
Schulz, Thadeus
Daniels, Wayne
Daly, Elizabeth R.
Andrew, Thomas A.
Brown, Catherine M.
Cummings, Peter
Nelson, Randall
Cartter, Matthew L.
Backenson, P. Bryon
White, Jennifer L.
Kurpiel, Philip M.
Rockwell, Russell
Rotans, Andrew S.
Hertzog, Christen
Squires, Linda S.
Linden, Jeanne V.
Prial, Margaret
House, Jennifer
Pontones, Pam
Batten, Brigid
Blau, Dianna
DeLeon-Carnes, Marlene
Muehlenbachs, Atis
Ritter, Jana
Sanders, Jeanine
Zaki, Sherif R.
Mead, Paul
Hinckley, Alison
Nelson, Christina
Perea, Anna
Schriefer, Martin
Molins, Claudia
Forrester, Joseph D.
TI Three Sudden Cardiac Deaths Associated with Lyme Carditis - United
States, November 2012-July 2013
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Article
ID DISEASE; BABESIOSIS
C1 [Ray, Gregory; Schulz, Thadeus; Daniels, Wayne] Cryolife Inc, Kennesaw, GA USA.
[Brown, Catherine M.] Massachusetts Dept Publ Hlth, Boston, MA 02111 USA.
[Backenson, P. Bryon; White, Jennifer L.; Kurpiel, Philip M.] New York State Dept Hlth, Albany, NY 12237 USA.
[Linden, Jeanne V.] New York State Dept Hlth, Wadsworth Ctr, Albany, NY 12237 USA.
[Prial, Margaret] Off Med Examiner, Orange Cty, NY USA.
[House, Jennifer; Pontones, Pam] Indiana State Dept Hlth, Indianapolis, IN 46202 USA.
[Forrester, Joseph D.] CDC, Atlanta, GA 30333 USA.
RP Forrester, JD (reprint author), CDC, Atlanta, GA 30333 USA.
EM jforrester@cdc.gov
NR 10
TC 24
Z9 24
U1 1
U2 2
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 13
PY 2013
VL 62
IS 49
BP 993
EP 996
PG 4
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 273WZ
UT WOS:000328568300001
ER
PT J
AU Bresee, J
Reed, C
Kim, IK
Finelli, L
Fry, A
Chaves, SS
Burns, E
Gargiullo, P
Jernigan, D
Cox, N
Singleton, J
Zhai, YS
O'Halloran, A
Kahn, K
Lu, PJ
Santibanez, TA
AF Bresee, Joseph
Reed, Carrie
Kim, Inkyu Kevin
Finelli, Lyn
Fry, Alicia
Chaves, Sandra S.
Burns, Erin
Gargiullo, Paul
Jernigan, Daniel
Cox, Nancy
Singleton, James
Zhai, Yusheng
O'Halloran, Alissa
Kahn, Katherine
Lu, Peng-Jun
Santibanez, Tammy A.
TI Estimated Influenza Illnesses and Hospitalizations Averted by Influenza
Vaccination - United States, 2012-13 Influenza Season
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Article
C1 [Bresee, Joseph; Reed, Carrie; Kim, Inkyu Kevin; Finelli, Lyn; Fry, Alicia; Chaves, Sandra S.; Burns, Erin; Gargiullo, Paul; Jernigan, Daniel; Cox, Nancy] CDC, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
[Singleton, James; Zhai, Yusheng; O'Halloran, Alissa; Kahn, Katherine; Lu, Peng-Jun; Santibanez, Tammy A.] CDC, Immunizat Svcs Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
RP Bresee, J (reprint author), CDC, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
EM jbresee@cdc.gov
NR 9
TC 33
Z9 33
U1 1
U2 3
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 13
PY 2013
VL 62
IS 49
BP 997
EP 1000
PG 4
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 273WZ
UT WOS:000328568300002
ER
PT J
AU Ahluwalia, IB
Ding, HL
Harrison, L
Austin, T
D'Angelo, D
Hastings, P
Ruffo, N
O'Neil, ME
Singleton, JA
Bridges, CB
AF Ahluwalia, Indu B.
Ding, Helen
Harrison, Leslie
Austin, Toyia
D'Angelo, Denise
Hastings, Phil
Ruffo, Nan
O'Neil, Mary Elizabeth
Singleton, James A.
Bridges, Carolyn B.
TI Seasonal Influenza Vaccination Coverage Among Women Who Delivered a
Live-Born Infant-21 States and New York City, 2009-10 and 2010-11
Influenza Seasons
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Article
ID PREGNANT-WOMEN; UNITED-STATES
C1 [Ahluwalia, Indu B.; Ding, Helen; Harrison, Leslie; Austin, Toyia; D'Angelo, Denise; Hastings, Phil; Ruffo, Nan; O'Neil, Mary Elizabeth] CDC, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USA.
[Singleton, James A.; Bridges, Carolyn B.] CDC, Immunizat Svcs Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
RP Ahluwalia, IB (reprint author), CDC, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USA.
EM iaa2@cdc.gov
NR 10
TC 4
Z9 4
U1 0
U2 0
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 13
PY 2013
VL 62
IS 49
BP 1001
EP 1004
PG 4
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 273WZ
UT WOS:000328568300003
ER
PT J
AU Cardemil, C
Ng, T
Pabst, L
AF Cardemil, Cristina
Ng, Terence
Pabst, Laura
TI Progress in Immunization Information Systems - United States, 2012
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Article
C1 [Cardemil, Cristina; Ng, Terence; Pabst, Laura] CDC, Immunizat Svcs Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
RP Cardemil, C (reprint author), CDC, Immunizat Svcs Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
EM ccardemil@cdc.gov
NR 10
TC 16
Z9 16
U1 0
U2 0
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 13
PY 2013
VL 62
IS 49
BP 1005
EP 1008
PG 4
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 273WZ
UT WOS:000328568300004
ER
PT J
AU Etsano, A
Shuaib, F
Mkanda, P
Banda, R
Korir, C
Corkum, M
Ndiaye, S
Ashenafi, S
Mahoney, F
Vertefeuille, JF
Burns, CC
AF Etsano, Andrew
Shuaib, Faisal
Mkanda, Pascal
Banda, Richard
Korir, Charles
Corkum, Melissa
Ndiaye, Serigne
Ashenafi, Samrawit
Mahoney, Frank
Vertefeuille, John F.
Burns, Cara C.
TI Progress Toward Poliomyelitis Eradication - Nigeria, January
2012-September 2013
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Article
C1 [Ndiaye, Serigne; Ashenafi, Samrawit; Mahoney, Frank; Vertefeuille, John F.] CDC, Global Immunizat Div, Ctr Global Hlth, Atlanta, GA 30333 USA.
[Burns, Cara C.] CDC, Div Viral Dis, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
RP Ndiaye, S (reprint author), CDC, Global Immunizat Div, Ctr Global Hlth, Atlanta, GA 30333 USA.
EM sndiaye@cdc.gov
NR 8
TC 15
Z9 15
U1 0
U2 0
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 13
PY 2013
VL 62
IS 49
BP 1009
EP 1013
PG 5
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 273WZ
UT WOS:000328568300005
ER
PT J
AU Turner, RE
Heetderks, AJ
Khan, AD
Chorba, TL
Jereb, JA
AF Turner, Rebekah E.
Heetderks, Andrew J.
Khan, Awal D.
Chorba, Terence L.
Jereb, John A.
TI Extent and Effects of Recurrent Shortages of Purified-Protein Derivative
Tuberculin Skin Test Antigen Solutions - United States, 2013
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Article
C1 [Turner, Rebekah E.; Heetderks, Andrew J.; Khan, Awal D.; Chorba, Terence L.; Jereb, John A.] CDC, Div TB Eliminat, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA 30333 USA.
RP Jereb, JA (reprint author), CDC, Div TB Eliminat, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA 30333 USA.
EM jjereb@cdc.gov
NR 5
TC 4
Z9 4
U1 0
U2 0
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 13
PY 2013
VL 62
IS 49
BP 1014
EP 1015
PG 2
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 273WZ
UT WOS:000328568300006
ER
PT J
AU Ghosh, T
Herlihy, R
Van Dyke, M
Kuhn, S
Sherry, B
Halliday, M
Spelke, B
Bayleyegn, T
Wolkin, A
Lewis, LS
Fechter-Leggett, E
Olayinka, O
AF Ghosh, Tista
Herlihy, Rachel
Van Dyke, Mike
Kuhn, Stephanie
Sherry, Burrer
Halliday, Melissa
Spelke, Bridget
Bayleyegn, Tesfaye
Wolkin, Amy
Lewis, Lauren S.
Fechter-Leggett, Ethan
Olayinka, Olaniyi
TI Severe Illness Associated with Reported Use of Synthetic Marijuana -
Colorado, August-September 2013
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Article
C1 [Olayinka, Olaniyi] CDC, Atlanta, GA 30333 USA.
RP Olayinka, O (reprint author), CDC, Atlanta, GA 30333 USA.
EM oolayinka@cdc.gov
OI Spelke, Bridget/0000-0002-5950-8197
NR 4
TC 15
Z9 16
U1 0
U2 1
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 13
PY 2013
VL 62
IS 49
BP 1016
EP 1017
PG 2
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 273WZ
UT WOS:000328568300007
ER
PT J
AU Brady, OJ
Johansson, MA
Guerra, CA
Bhatt, S
Golding, N
Pigott, DM
Delatte, H
Grech, MG
Leisnham, PT
Maciel-de-Freitas, R
Styer, LM
Smith, DL
Scott, TW
Gething, PW
Hay, SI
AF Brady, Oliver J.
Johansson, Michael A.
Guerra, Carlos A.
Bhatt, Samir
Golding, Nick
Pigott, David M.
Delatte, Helene
Grech, Marta G.
Leisnham, Paul T.
Maciel-de-Freitas, Rafael
Styer, Linda M.
Smith, David L.
Scott, Thomas W.
Gething, Peter W.
Hay, Simon I.
TI Modelling adult Aedes aegypti and Aedes albopictus survival at different
temperatures in laboratory and field settings
SO PARASITES & VECTORS
LA English
DT Article
DE Aedes; Survival; Temperature; Mortality; Longevity; Modelling;
Mark-release-recapture; Dengue; Transmission; Generalised additive
models
ID DENGUE VIRUS TRANSMISSION; BLOOD PLUS SUGAR; RIO-DE-JANEIRO;
DIPTERA-CULICIDAE; RELEASE-RECAPTURE; PUERTO-RICO; CONTAINER
PRODUCTIVITY; LIFE TABLE; MORTALITY; MOSQUITOS
AB Background: The survival of adult female Aedes mosquitoes is a critical component of their ability to transmit pathogens such as dengue viruses. One of the principal determinants of Aedes survival is temperature, which has been associated with seasonal changes in Aedes populations and limits their geographical distribution. The effects of temperature and other sources of mortality have been studied in the field, often via mark-release-recapture experiments, and under controlled conditions in the laboratory. Survival results differ and reconciling predictions between the two settings has been hindered by variable measurements from different experimental protocols, lack of precision in measuring survival of free-ranging mosquitoes, and uncertainty about the role of age-dependent mortality in the field.
Methods: Here we apply generalised additive models to data from 351 published adult Ae. aegypti and Ae. albopictus survival experiments in the laboratory to create survival models for each species across their range of viable temperatures. These models are then adjusted to estimate survival at different temperatures in the field using data from 59 Ae. aegypti and Ae. albopictus field survivorship experiments. The uncertainty at each stage of the modelling process is propagated through to provide confidence intervals around our predictions.
Results: Our results indicate that adult Ae. albopictus has higher survival than Ae. aegypti in the laboratory and field, however, Ae. aegypti can tolerate a wider range of temperatures. A full breakdown of survival by age and temperature is given for both species. The differences between laboratory and field models also give insight into the relative contributions to mortality from temperature, other environmental factors, and senescence and over what ranges these factors can be important.
Conclusions: Our results support the importance of producing site-specific mosquito survival estimates. By including fluctuating temperature regimes, our models provide insight into seasonal patterns of Ae. aegypti and Ae. albopictus population dynamics that may be relevant to seasonal changes in dengue virus transmission. Our models can be integrated with Aedes and dengue modelling efforts to guide and evaluate vector control, better map the distribution of disease and produce early warning systems for dengue epidemics.
C1 [Brady, Oliver J.; Guerra, Carlos A.; Bhatt, Samir; Golding, Nick; Pigott, David M.; Gething, Peter W.; Hay, Simon I.] Univ Oxford, Dept Zool, Spatial Ecol & Epidemiol Grp, Tinbergen Bldg,South Parks Rd, Oxford, England.
[Johansson, Michael A.] Ctr Dis Control & Prevent, Dengue Branch, Div Vector Borne Dis, San Juan, PR USA.
[Delatte, Helene] CIRAD, UMR PVBMT, St Piarre 97410, Reunion.
[Grech, Marta G.] Univ Nacl Patagonia San Juan Bosco, FCN Sede, Lab Invest Ecol & Sistemat Anim, Esquel, Chubut, Argentina.
[Leisnham, Paul T.] Univ Maryland, Dept Environm Sci & Technol, College Pk, MD 20742 USA.
[Maciel-de-Freitas, Rafael] Fiocruz MS, Inst Oswaldo Cruz, Lab Transmissores Hematozoarios, BR-21045900 Rio De Janeiro, RJ, Brazil.
[Styer, Linda M.] New York State Dept Hlth, Wadsworth Ctr, Albany, NY 12208 USA.
[Smith, David L.] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.
[Scott, Thomas W.] Univ Calif Davis, Dept Entomol, Davis, CA 95616 USA.
[Smith, David L.; Scott, Thomas W.; Hay, Simon I.] NIH, Fogarty Int Ctr, Bethesda, MD 20892 USA.
RP Brady, OJ (reprint author), Univ Oxford, Dept Zool, Spatial Ecol & Epidemiol Grp, Tinbergen Bldg,South Parks Rd, Oxford, England.
EM oliver.brady@zoo.ox.ac.uk
RI Hay, Simon/F-8967-2015;
OI Hay, Simon/0000-0002-0611-7272; Pigott, David/0000-0002-6731-4034;
Golding, Nick/0000-0001-8916-5570; Gething, Peter/0000-0001-6759-5449;
Brady, Oliver/0000-0002-3235-2129
FU BBSRC studentship; Department of Zoology at the University of Oxford;
Medical Research Council (UK) Career Development Fellow [K00669X]; Bill
and Melinda Gates Foundation [OPP1068048]; Bill AMP; Melinda Gates
Foundation [OPP1053338]; Wellcome Trust [095066]; EU [21803]; RAPIDD
program of the Science AMP; Technology Directorate; Department of
Homeland Security; Fogarty International Center, National Institutes of
Health
FX O.J.B. is funded by a BBSRC studentship. DMP is funded by a Sir Richard
Southwood Graduate Scholarship from the Department of Zoology at the
University of Oxford. P.W.G is a Medical Research Council (UK) Career
Development Fellow (#K00669X) and receives support from the Bill and
Melinda Gates Foundation (#OPP1068048) which also supports S.B. N.G. is
funded by a grant from the Bill & Melinda Gates Foundation (OPP1053338).
S. I. H. is funded by a Senior Research Fellowship from the Wellcome
Trust (095066). This study was partially funded by EU grant 21803 IDAMS
(http://www.idams.eu). The contents of this publication are the sole
responsibility of the authors and don't necessarily reflect the views of
the European Commission. S.I.H. C.A.G. and T.W.S. also acknowledge
funding support from the RAPIDD program of the Science & Technology
Directorate, Department of Homeland Security, and the Fogarty
International Center, National Institutes of Health.
NR 79
TC 56
Z9 56
U1 5
U2 58
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1756-3305
J9 PARASITE VECTOR
JI Parasites Vectors
PD DEC 12
PY 2013
VL 6
AR 351
DI 10.1186/1756-3305-6-351
PG 12
WC Parasitology
SC Parasitology
GA 277RW
UT WOS:000328838000002
PM 24330720
ER
PT J
AU Wiringa, AE
Shutt, KA
Marsh, JW
Cohn, AC
Messonnier, NE
Zansky, SM
Petit, S
Farley, MM
Gershman, K
Lynfield, R
Reingold, A
Schaffner, W
Thompson, J
Brown, ST
Lee, BY
Harrison, LH
AF Wiringa, Ann E.
Shutt, Kathleen A.
Marsh, Jane W.
Cohn, Amanda C.
Messonnier, Nancy E.
Zansky, Shelley M.
Petit, Susan
Farley, Monica M.
Gershman, Ken
Lynfield, Ruth
Reingold, Arthur
Schaffner, William
Thompson, Jamie
Brown, Shawn T.
Lee, Bruce Y.
Harrison, Lee H.
TI Geotemporal Analysis of Neisseria meningitidis Clones in the United
States: 2000-2005
SO PLOS ONE
LA English
DT Article
ID INVASIVE MENINGOCOCCAL DISEASE; OUTBREAK DETECTION; SURVEILLANCE;
INFECTION; RISK
AB Background: The detection of meningococcal outbreaks relies on serogrouping and epidemiologic definitions. Advances in molecular epidemiology have improved the ability to distinguish unique Neisseria meningitidis strains, enabling the classification of isolates into clones. Around 98% of meningococcal cases in the United States are believed to be sporadic.
Methods: Meningococcal isolates from 9 Active Bacterial Core surveillance sites throughout the United States from 2000 through 2005 were classified according to serogroup, multilocus sequence typing, and outer membrane protein (porA, porB, and fetA) genotyping. Clones were defined as isolates that were indistinguishable according to this characterization. Case data were aggregated to the census tract level and all non-singleton clones were assessed for non-random spatial and temporal clustering using retrospective space-time analyses with a discrete Poisson probability model.
Results: Among 1,062 geocoded cases with available isolates, 438 unique clones were identified, 78 of which had >= 2 isolates. 702 cases were attributable to non-singleton clones, accounting for 66.0% of all geocoded cases. 32 statistically significant clusters comprised of 107 cases (10.1% of all geocoded cases) were identified. Clusters had the following attributes: included 2 to 11 cases; 1 day to 33 months duration; radius of 0 to 61.7 km; and attack rate of 0.7 to 57.8 cases per 100,000 population. Serogroups represented among the clusters were: B (n = 12 clusters, 45 cases), C (n = 11 clusters, 27 cases), and Y (n = 9 clusters, 35 cases); 20 clusters (62.5%) were caused by serogroups represented in meningococcal vaccines that are commercially available in the United States.
Conclusions: Around 10% of meningococcal disease cases in the U.S. could be assigned to a geotemporal cluster. Molecular characterization of isolates, combined with geotemporal analysis, is a useful tool for understanding the spread of virulent meningococcal clones and patterns of transmission in populations.
C1 [Wiringa, Ann E.] Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA USA.
[Shutt, Kathleen A.; Marsh, Jane W.; Harrison, Lee H.] Univ Pittsburgh, Grad Sch Publ Hlth, Infect Dis Epidemiol Res Unit, Pittsburgh, PA 15260 USA.
[Shutt, Kathleen A.; Marsh, Jane W.; Harrison, Lee H.] Univ Pittsburgh, Sch Med, Pittsburgh, PA USA.
[Cohn, Amanda C.; Messonnier, Nancy E.] Ctr Dis Control & Prevent, Meningitis & Vaccine Preventable Dis Branch, Div Bacterial Dis, Atlanta, GA USA.
[Zansky, Shelley M.] New York State Dept Hlth, Albany, NY USA.
[Petit, Susan] Connecticut Dept Publ Hlth, Hartford, CT USA.
[Farley, Monica M.] Emory Univ, Atlanta, GA 30322 USA.
[Farley, Monica M.] VA Med Ctr, Atlanta, GA USA.
[Gershman, Ken] Colorado Dept Publ Hlth & Environm, Denver, CO USA.
[Lynfield, Ruth] Minnesota Dept Hlth, St Paul, MN USA.
[Reingold, Arthur] Univ Calif Berkeley, Berkeley, CA 94720 USA.
[Schaffner, William] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA.
[Thompson, Jamie] Oregon Publ Hlth Div, Portland, OR USA.
[Brown, Shawn T.] Carnegie Mellon Univ, Pittsburgh Supercomp Ctr, Pittsburgh, PA 15213 USA.
[Lee, Bruce Y.] Univ Pittsburgh, Sch Med, Publ Hlth Computat & Operat Res PHICOR, Pittsburgh, PA USA.
[Lee, Bruce Y.] Univ Pittsburgh, Grad Sch Publ Hlth, Pittsburgh, PA USA.
[Harrison, Lee H.] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Int Hlth, Baltimore, MD USA.
RP Harrison, LH (reprint author), Univ Pittsburgh, Grad Sch Publ Hlth, Infect Dis Epidemiol Res Unit, Pittsburgh, PA 15260 USA.
EM lharriso@edc.pitt.edu
OI Shutt, Kathleen/0000-0003-3376-6152
FU US Centers for Disease Control and Prevention [DHM 99-006042]
FX This study was supported by the US Centers for Disease Control and
Prevention grant DHM 99-006042. The funders had no role in study design,
data collection and analysis, decision to publish, or preparation of the
manuscript. CDC coauthors participated in various aspects of the study
and manuscript reparation.
NR 32
TC 5
Z9 5
U1 0
U2 4
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 12
PY 2013
VL 8
IS 12
AR e82048
DI 10.1371/journal.pone.0082048
PG 9
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 276EU
UT WOS:000328731800035
PM 24349182
ER
PT J
AU Aminov, Z
Haase, RF
Pavuk, M
Carpenter, DO
AF Aminov, Zafar
Haase, Richard F.
Pavuk, Marian
Carpenter, David O.
CA Anniston Environm Hlth Res Consort
TI Analysis of the effects of exposure to polychlorinated biphenyls and
chlorinated pesticides on serum lipid levels in residents of Anniston,
Alabama
SO ENVIRONMENTAL HEALTH
LA English
DT Article
DE Cholesterol; Triglycerides; Persistent organic pollutants; LDL
cholesterol; HDL cholesterol; Hexachlorobenzene; DDT; PCBs
ID PERSISTENT ORGANIC POLLUTANTS; HEPATIC GENE-EXPRESSION;
CARDIOVASCULAR-DISEASE; RAT-LIVER; LIPOPROTEIN CHOLESTEROL; PCBS;
METABOLISM; PROTEIN; HEALTH; ADJUSTMENT
AB Background: Anniston, Alabama, is the site of a former Monsanto plant where polychlorinated biphenyls (PCBs) were manufactured from 1929 until 1971. Residents of Anniston are known to have elevated levels of PCBs. The objective of the study was to test the hypothesis that levels of the various lipid components (total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides) are differentially associated with concentrations of total PCBs and total pesticides, and further that different congeners, congener groups and different pesticides do not have identical associations in serum samples obtained from Anniston residents in a cross-sectional study.
Methods: Fasting serum samples were obtained from 575 residents of Anniston who were not on any lipid-lowering medication and were analyzed for 35 PCB congeners, nine chlorinated pesticides, total cholesterol, LDL and HDL cholesterol and triglyceride concentrations. Associations between toxicant concentrations and lipid levels were determined using multiple linear regression analysis.
Results: We observed that elevated serum concentrations of lipids were associated with elevated serum concentrations of SPCBs and summed pesticides in analyses adjusted for age, race, gender, BMI, alcohol consumption, smoking and exercising status. The strongest associations were seen for PCB congeners with three, four, or at least eight substituted chlorines. Mono-ortho substituted congeners 74 and 156, di-ortho congeners 172 and 194, and tri- and tetra-ortho congeners 199, 196-203, 206 and 209 each were significantly associated with total lipids, total cholesterol and triglycerides. Serum concentrations of HCB and chlordane also had strong associations with lipid components.
Conclusions: Increased concentrations of PCBs and organochlorine pesticides are associated with elevations in total serum lipids, total cholesterol and triglycerides, but the patterns are different for different groups of PCBs and different pesticides. These observations show selective effects of different organochlorines on serum concentrations of different groups of lipids. This elevation in concentrations of serum lipids may be the basis for the increased incidence of cardiovascular disease found in persons with elevated exposures to PCBs and chlorinated pesticides.
C1 [Aminov, Zafar; Haase, Richard F.; Carpenter, David O.] Univ Albany, Inst Hlth & Environm, Rensselaer, NY 12144 USA.
[Pavuk, Marian] Agcy Tox Subst & Dis Registry, Atlanta, GA USA.
RP Carpenter, DO (reprint author), Univ Albany, Inst Hlth & Environm, 5 Univ Pl, Rensselaer, NY 12144 USA.
EM dcarpenter@albany.edu
FU Agency for Toxic Substances and Disease Registry [5U50TS473215];
Passport Foundation
FX The data collection was supported by a grant from the Agency for Toxic
Substances and Disease Registry to Jacksonville State University, #
5U50TS473215. We thank Wayman Turner and Andreas Sjodin at the National
Center for Environmental Health's Division of Laboratory Sciences,
Center for Disease Control and Prevention, Atlanta, GA, for their expert
analytical work on this study. The Anniston Environmental Health
Research Consortium Steering Committee members include Shirley Baker,
community representative; Scott Bartell, UC Irvine; James Olson,
University at Buffalo; Russell Foushee, Alan Percy, University of
Alabama at Birmingham; David O. Carpenter, University at Albany; Jane
Cash; Martha Lavender, Christie Shelton, Jacksonville State University;
Howard Frumkin, University of Washington; Marian Pavuk ATSCR/CDC; Paula
Rosenbaum, Allen Silverstone, Ruth Weinstock, Upstate Medical
University; and Kirsten Moysich, Roswell Park Cancer Institute. ZA was
supported by a grant from the Passport Foundation to the Institute for
Health and the Environment of the University at Albany. The contents of
this publication are solely the responsibility of the authors and do not
necessarily represent ATSDR's official views.
NR 50
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U1 0
U2 20
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1476-069X
J9 ENVIRON HEALTH-GLOB
JI Environ. Health
PD DEC 11
PY 2013
VL 12
AR 108
DI 10.1186/1476-069X-12-108
PG 13
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA 297VZ
UT WOS:000330284500001
PM 24325314
ER
PT J
AU Kawwass, JF
Monsour, M
Crawford, S
Kissin, DM
Session, DR
Kulkarni, AD
Jamieson, DJ
AF Kawwass, Jennifer F.
Monsour, Michael
Crawford, Sara
Kissin, Dmitry M.
Session, Donna R.
Kulkarni, Aniket D.
Jamieson, Denise J.
CA Natl ART Surveillance Syst NASS Gr
TI Trends and Outcomes for Donor Oocyte Cycles in the United States,
2000-2010
SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
LA English
DT Article
ID ASSISTED REPRODUCTIVE TECHNOLOGY; SINGLE-EMBRYO-TRANSFER; PERINATAL
OUTCOMES; MATERNAL AGE; PREGNANCY; WOMEN; DONATION; RISKS
AB IMPORTANCE The prevalence of oocyte donation for in vitro fertilization (IVF) has increased in the United States, but little information is available regarding maternal or infant outcomes to improve counseling and clinical decision making.
OBJECTIVES To quantify trends in donor oocyte cycles in the United States and to determine predictors of a good perinatal outcome among IVF cycles using fresh (noncryopreserved) embryos derived from donor oocytes.
DESIGN, SETTING, AND PARTICIPANTS Analysis of data from the Centers for Disease Control and Prevention's National ART Surveillance System, to which fertility centers are mandated to report and which includes data on more than 95% of all IVF cycles performed in the United States. Data from 2000 to 2010 described trends. Data from 2010 determined predictors.
MAIN OUTCOMES AND MEASURES Good perinatal outcome, defined as a singleton live-born infant delivered at 37 weeks or later and weighing 2500 g or more.
RESULTS From 2000 to 2010, data from 443 clinics (93% of all US fertility centers) were included. The annual number of donor oocyte cycles significantly increased, from 10 801 to 18 306. Among all donor oocyte cycles, an increasing trend was observed from 2000 to 2010 in the proportion of cycles using frozen (vs fresh) embryos (26.7%[95% CI, 25.8%-27.5%] to 40.3%[95% CI, 39.6%-41.1%]) and elective single-embryo transfers (vs transfer of multiple embryos) (0.8%[95% CI, 0.7%-1.0%] to 14.5%[95% CI, 14.0%-15.1%]). Good perinatal outcomes increased from 18.5%(95% CI, 17.7%-19.3%) to 24.4%(95% CI, 23.8%-25.1%) (P < .001 for all listed trends). Mean donor and recipient ages remained stable at 28 (SD, 2.8) years and 41 (SD, 5.3) years, respectively. In 2010, 396 clinics contributed data. For donor oocyte cycles using fresh embryos (n = 9865), 27.5%(95% CI, 26.6%-28.4%) resulted in good perinatal outcome. Transfer of an embryo at day 5 (adjusted odds ratio [OR], 1.17 [95% CI, 1.04-1.32]) and elective single-embryo transfers (adjusted OR, 2.32 [95% CI, 1.92-2.80]) were positively associated with good perinatal outcome; tubal (adjusted OR, 0.72 [95% CI, 0.60-0.86]) or uterine (adjusted OR, 0.74 [95% CI, 0.58-0.94]) factor infertility and non-Hispanic black recipient race/ethnicity (adjusted OR, 0.48 [95% CI, 0.35-0.67]) were associated with decreased odds of good outcome. Recipient age was not associated with likelihood of good perinatal outcome.
CONCLUSIONS AND RELEVANCE In the United States from 2000 to 2010, there was an increase in number of donor oocyte cycles, accompanied by an increase in good outcomes. Further studies are needed to understand the mechanisms underlying the factors associated with less successful outcomes.
C1 [Kawwass, Jennifer F.; Kissin, Dmitry M.; Session, Donna R.; Jamieson, Denise J.] Emory Univ, Sch Med, Dept Gynecol & Obstet, Div Reprod Endocrinol & Infertil, Atlanta, GA 30308 USA.
[Kawwass, Jennifer F.; Monsour, Michael; Crawford, Sara; Kissin, Dmitry M.; Kulkarni, Aniket D.; Jamieson, Denise J.] Ctr Dis Control & Prevent, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA.
RP Kawwass, JF (reprint author), Emory Univ, Sch Med, Dept Gynecol & Obstet, 550 Peachtree St,Ste 1800, Atlanta, GA 30308 USA.
EM jennifer.kawwass@emory.edu
FU Intramural CDC HHS [CC999999]
NR 23
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Z9 29
U1 0
U2 3
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 515 N STATE ST, CHICAGO, IL 60654-0946 USA
SN 0098-7484
EI 1538-3598
J9 JAMA-J AM MED ASSOC
JI JAMA-J. Am. Med. Assoc.
PD DEC 11
PY 2013
VL 310
IS 22
BP 2426
EP 2434
DI 10.1001/jama.2013.280924
PG 9
WC Medicine, General & Internal
SC General & Internal Medicine
GA 266NN
UT WOS:000328030900023
PM 24135860
ER
PT J
AU Zhang, XY
Morrison-Carpenter, T
Holt, JB
Callahan, DB
AF Zhang, Xingyou
Morrison-Carpenter, Teresa
Holt, James B.
Callahan, David B.
TI Trends in adult current asthma prevalence and contributing risk factors
in the United States by state: 2000-2009
SO BMC PUBLIC HEALTH
LA English
DT Article
DE Current asthma; Smoking; Obesity; Trend; The United States
ID OUTDOOR AIR-POLLUTION; BODY-MASS INDEX; SELF-REPORTED ASTHMA; ONSET
ASTHMA; RESPIRATORY SYMPTOMS; BRONCHIAL HYPERRESPONSIVENESS; PROSPECTIVE
COHORT; CHILDHOOD ASTHMA; INCIDENT ASTHMA; SMOKE EXPOSURE
AB Background: Current asthma prevalence among adults in the United States has reached historically high levels. Although national-level estimates indicate that asthma prevalence among adults increased by 33% from 2000 to 2009, state-specific temporal trends of current asthma prevalence and their contributing risk factors have not been explored.
Methods: We used 2000-2009 Behavioral Risk Factor Surveillance System data from all 50 states and the District of Columbia (D.C.) to estimate state-specific current asthma prevalence by 2-year periods (2000-2001, 2002-2003, 2004-2005, 2006-2007, 2008-2009). We fitted a series of four logistic-regression models for each state to evaluate whether there was a statistically significant linear change in the current asthma prevalence over time, accounting for sociodemographic factors, smoking status, and weight status (using body mass index as the indicator).
Results: During 2000-2009, current asthma prevalence increased in all 50 states and D.C., with significant increases in 46/50 (92%) states and D.C. After accounting for weight status in the model series with sociodemographic factors, and smoking status, 10 states (AR, AZ, IA, IL, KS, ME, MT, UT, WV, and WY) that had previously shown a significant increase did not show a significant increase in current asthma prevalence.
Conclusions: There was a significant increasing trend in state-specific current asthma prevalence among adults from 2000 to 2009 in most states in the United States. Obesity prevalence appears to contribute to increased current asthma prevalence in some states.
C1 [Zhang, Xingyou; Holt, James B.] Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Div Populat Hlth, Atlanta, GA 30341 USA.
[Morrison-Carpenter, Teresa; Callahan, David B.] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Air Pollut & Resp Hlth Branch, Atlanta, GA USA.
RP Zhang, XY (reprint author), Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Div Populat Hlth, 4770 Buford Highway,Mailstop F78, Atlanta, GA 30341 USA.
EM gyx8@cdc.gov
NR 67
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U1 1
U2 5
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1471-2458
J9 BMC PUBLIC HEALTH
JI BMC Public Health
PD DEC 10
PY 2013
VL 13
AR 1156
DI 10.1186/1471-2458-13-1156
PG 11
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 284IC
UT WOS:000329308500004
PM 24325173
ER
PT J
AU Masanja, IM
Selemani, M
Khatib, RA
Amuri, B
Kuepfer, I
Kajungu, D
de Savigny, D
Kachur, SP
Skarbinski, J
AF Masanja, Irene M.
Selemani, Majige
Khatib, Rashid A.
Amuri, Baraka
Kuepfer, Irene
Kajungu, Dan
de Savigny, Don
Kachur, S. Patrick
Skarbinski, Jacek
TI Correct dosing of artemether-lumefantrine for management of
uncomplicated malaria in rural Tanzania: do facility and patient
characteristics matter?
SO MALARIA JOURNAL
LA English
DT Article
DE Artemether lumefantrine dosing; Uncomplicated malaria; Tanzania
ID RAPID DIAGNOSTIC-TESTS; TREATMENT POLICY; HEALTH FACILITIES; QUALITY
AB Background: Use of artemisinin-based combination therapy (ACT), such as artemether-lumefantrine (AL), requires a strict dosing schedule that follows the drugs' pharmacokinetic properties. The quality of malaria case management was assessed in two areas in rural Tanzania, to ascertain patient characteristics and facility-specific factors that influence correct dosing of AL for management of uncomplicated malaria.
Methods: Exit interviews were conducted with patients attending health facilities for initial illness consultation. Information about health workers' training and supervision visits was collected. Health facilities were inventoried for capacity and availability of medical products related to care of malaria patients. The outcome was correct dosing of AL based on age and weight. Logistic regression was used to assess health facility factors and patient characteristics associated with correct dosing of AL by age and weight.
Results: A total of 1,531 patients were interviewed, but 60 pregnant women were excluded from the analysis. Only 503 (34.2%) patients who received AL were assessed for correct dosing. Most patients who received AL (85.3%) were seen in public health facilities, 75.7% in a dispensary and 91.1% in a facility that had AL in stock on the survey day. Overall, 92.1% (463) of AL prescriptions were correct by age or weight; but 85.7% of patients received correct dosing by weight alone and 78.5% received correct dosing by age alone. In multivariate analysis, patients in the middle dosing bands in terms of age or weight, had statistically significant lower odds of correct AL dosing (p < 0.05) compared to those in the lowest age or weight group. Other factors such as health worker supervision and training on ACT did not improve the odds of correct AL dosing.
Conclusion: Although malaria treatment guidelines indicate AL dosing can be prescribed based on age or weight of the patient, findings from this study show that patients within the middle age and weight dosing bands were least likely to receive a correct dose by either measure. Clinicians should be made aware of AL dosing errors for patients aged three to 12 years and advised to use weight-based prescriptions whenever possible.
C1 [Masanja, Irene M.; Selemani, Majige; Khatib, Rashid A.; Amuri, Baraka] Ifakara Hlth Inst, Dar Es Salaam, Tanzania.
[Masanja, Irene M.; Kuepfer, Irene; de Savigny, Don] Swiss Trop & Publ Hlth Inst, CH-4002 Basel, Switzerland.
[Masanja, Irene M.; de Savigny, Don] Univ Basel, CH-4003 Basel, Switzerland.
[Masanja, Irene M.; Selemani, Majige; Khatib, Rashid A.; Amuri, Baraka; Kuepfer, Irene; Kajungu, Dan; de Savigny, Don; Kachur, S. Patrick; Skarbinski, Jacek] INDEPTH Network Effectiveness & Safety Studies A, Dar Es Salaam, Tanzania.
[Kachur, S. Patrick; Skarbinski, Jacek] US Ctr Dis Control & Prevent, Ctr Global Hlth, Malaria Branch, Atlanta, GA USA.
RP Masanja, IM (reprint author), Ifakara Hlth Inst, POB 78373, Dar Es Salaam, Tanzania.
EM imasanja@ihi.or.tz
RI AMURI, Mbaraka/C-5386-2011
OI AMURI, Mbaraka/0000-0002-8583-9555
FU Ifakara Health Institute administration department; Ifakara Health
Institute procurement department; Ifakara Health Institute finance
department
FX The authors are grateful to all health providers and patients who
participated in the surveys. Sincere appreciation also goes to all field
workers who spent long hours in the field for interview and chasing
blood smears results to return them to respective facilities before
moving on to the next one. In addition, we thank the study microscopist
Mr. Bakari Kissa and field supervisor Mr. Ismail Mninge for their
commendable commitment to implement quality study protocols. Lastly, we
are grateful to the Ifakara Health Institute administration, procurement
and finance departments for the support they provided throughout the
study period.
NR 14
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PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1475-2875
J9 MALARIA J
JI Malar. J.
PD DEC 10
PY 2013
VL 12
AR 446
DI 10.1186/1475-2875-12-446
PG 8
WC Infectious Diseases; Parasitology; Tropical Medicine
SC Infectious Diseases; Parasitology; Tropical Medicine
GA 281OJ
UT WOS:000329110600002
PM 24325267
ER
PT J
AU Halsey, NA
Griffioen, M
Dreskin, SC
Dekker, CL
Wood, R
Sharma, D
Jones, JF
LaRussa, PS
Garner, J
Berger, M
Proveaux, T
Vellozzi, C
Broder, K
Setse, R
Pahud, B
Hrncir, D
Choi, H
Sparks, R
Williams, SE
Engler, RJ
Gidudu, J
Baxter, R
Klein, N
Edwards, K
Cano, M
Kelso, JM
AF Halsey, Neal A.
Griffioen, Mari
Dreskin, Stephen C.
Dekker, Cornelia L.
Wood, Robert
Sharma, Devindra
Jones, James F.
LaRussa, Philip S.
Garner, Jenny
Berger, Melvin
Proveaux, Tina
Vellozzi, Claudia
Broder, Karen
Setse, Rosanna
Pahud, Barbara
Hrncir, David
Choi, Howard
Sparks, Robert
Williams, Sarah Elizabeth
Engler, Renata J.
Gidudu, Jane
Baxter, Roger
Klein, Nicola
Edwards, Kathryn
Cano, Maria
Kelso, John M.
CA Hypersensitivity Working Grp Clin
TI Immediate hypersensitivity reactions following monovalent 2009 pandemic
influenza A (H1N1) vaccines: Reports to VAERS
SO VACCINE
LA English
DT Article
DE Immunization; Influenza vaccine; Hypersensitivity; Anaphylaxis;
Urticaria; Allergic reactions; H1N1 influenza vaccine
ID DUCK RUBELLA VACCINE; ADVERSE EVENTS; ANAPHYLAXIS; SAFETY; AGE;
EMERGENCY; PROJECT; NETWORK
AB Background: Hypersensitivity disorders following vaccinations are a cause for concern. Objective: To determine the type and rate by age, gender, and vaccine received for reported hypersensitivity reactions following monovalent 2009 pandemic influenza A (H1N1) vaccines.
Design: A systematic review of reports to the Vaccine Adverse Event Reporting System (VAERS) following monovalent 2009 pandemic influenza A (H1N1) vaccines. Setting/patients: US Civilian reports following vaccine received from October 1, 2009 through May 31, 2010.
Measurements: Age, gender, vaccines received, diagnoses, clinical signs, and treatment were reviewed by nurses and physicians with expertise in vaccine adverse events. A panel of experts, including seven allergists reviewed complex illnesses and those with conflicting evidence for classification of the event.
Results: Of 1984 reports, 1286 were consistent with immediate hypersensitivity disorders and 698 were attributed to anxiety reactions, syncope, or other illnesses. The female-to-male ratio was >4:1 for persons 20-to-59 years of age, but approximately equal for children under 10. One hundred eleven reports met Brighton Collaboration criteria for anaphylaxis; only one-half received epinephrine for initial therapy. The overall rate of reported hypersensitivity reactions was 10.7 per million vaccine doses distributed, with a 2-fold higher rate for live vaccine.
Limitations: Underreporting, especially of mild events, would result in an underestimate of the true rate of immediate hypersensitivity reactions. Selective reporting of events in adult females could have resulted in higher rates than reported for males.
Conclusions: Adult females may be at higher risk of hypersensitivity reactions after influenza vaccination than men. Although the risk of hypersensitivity reactions following 2009 pandemic influenza A (H1N1) vaccines was low, all clinics administering vaccines should be familiar with treatment guidelines for these adverse events, including the use of intramuscular epinephrine early in the course of serious hypersensitivity reactions. (C) 2013 Elsevier Ltd. All rights reserved.
C1 [Halsey, Neal A.; Griffioen, Mari; Garner, Jenny; Proveaux, Tina; Setse, Rosanna; Choi, Howard] Johns Hopkins Bloomberg Sch Publ Hlth, Inst Vaccine Safety, Baltimore, MD 21205 USA.
[Dreskin, Stephen C.] Univ Colorado, Dept Med, Denver, CO USA.
[Dekker, Cornelia L.] Stanford Univ, Sch Med, Dept Pediat, Stanford, CA 94305 USA.
[Wood, Robert] Johns Hopkins Univ, Sch Med, Dept Pediat, Div Allergy & Immunol, Baltimore, MD 21205 USA.
[Sharma, Devindra; Vellozzi, Claudia; Broder, Karen; Gidudu, Jane; Cano, Maria] Ctr Dis Control & Prevent, Immunizat Safety Off, Atlanta, GA USA.
[Jones, James F.] Ctr Dis Control & Prevent, Chron Viral Dis Branch, Atlanta, GA USA.
[LaRussa, Philip S.] Columbia Univ, Dept Pediat, Div Pediat Infect Dis, New York, NY 10027 USA.
[Berger, Melvin] CSL Behring, King Of Prussia, PA USA.
[Pahud, Barbara] Univ Missouri, Childrens Mercy Hosp & Clin, Kansas City, MO 64110 USA.
[Hrncir, David; Engler, Renata J.] Walter Reed Natl Mil Med Ctr, US Army Publ Hlth Command, Mil Vaccine Agcy, Vaccine Healthcare Ctr Network, Bethesda, MD USA.
[Sparks, Robert; Williams, Sarah Elizabeth; Edwards, Kathryn] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA.
[Baxter, Roger; Klein, Nicola] Kaiser Permanente Vaccine Study Ctr, Oakland, CA USA.
[Kelso, John M.] Scripps Clin, Div Allergy Asthma & Immunol, San Diego, CA USA.
RP Halsey, NA (reprint author), Johns Hopkins Bloomberg Sch Publ Hlth, Inst Vaccine Safety, 615 N Wolfe St,Room W5041, Baltimore, MD 21205 USA.
EM nhalsey@jhsph.edu
RI Garner, Joseph/C-8422-2009
FU Clinical Immunization Safety Assessment Network; Centers for Disease
Control and Prevention (CDC) [200-2002-00732]
FX We thank Elaine Miller and Oidda Museru for their assistance in
obtaining reports from the Vaccine Adverse Event Reporting System. This
study was supported by the Clinical Immunization Safety Assessment
Network and Vaccine Safety Datalink through a subcontract with America's
Health Insurance Plans under contract 200-2002-00732 from the Centers
for Disease Control and Prevention (CDC).
NR 32
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U1 1
U2 7
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 9
PY 2013
VL 31
IS 51
BP 6107
EP 6112
DI 10.1016/j.vaccine.2013.09.066
PG 6
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 280EB
UT WOS:000329010400012
PM 24120547
ER
PT J
AU Schulte, PA
Geraci, CL
Murashov, V
Kuempel, ED
Zumwalde, RD
Castranova, V
Hoover, MD
Hodson, L
Martinez, KF
AF Schulte, P. A.
Geraci, C. L.
Murashov, V.
Kuempel, E. D.
Zumwalde, R. D.
Castranova, V.
Hoover, M. D.
Hodson, L.
Martinez, K. F.
TI Occupational safety and health criteria for responsible development of
nanotechnology
SO JOURNAL OF NANOPARTICLE RESEARCH
LA English
DT Editorial Material
DE Risk assessment; Ethics; Risk management; Regulation; Toxicology;
Environmental and health effects
ID EXPOSURE CONTROL LIMITS; RISK-MANAGEMENT; ENGINEERED NANOMATERIALS;
PULMONARY RESPONSES; CARBON NANOTUBE; AIR-POLLUTION; MEASUREMENT
STRATEGIES; EPIDEMIOLOGIC-RESEARCH; MEDICAL-SURVEILLANCE; INHALATION
EXPOSURE
AB Organizations around the world have called for the responsible development of nanotechnology. The goals of this approach are to emphasize the importance of considering and controlling the potential adverse impacts of nanotechnology in order to develop its capabilities and benefits. A primary area of concern is the potential adverse impact on workers, since they are the first people in society who are exposed to the potential hazards of nanotechnology. Occupational safety and health criteria for defining what constitutes responsible development of nanotechnology are needed. This article presents five criterion actions that should be practiced by decision-makers at the business and societal levels-if nanotechnology is to be developed responsibly. These include (1) anticipate, identify, and track potentially hazardous nanomaterials in the workplace; (2) assess workers' exposures to nanomaterials; (3) assess and communicate hazards and risks to workers; (4) manage occupational safety and health risks; and (5) foster the safe development of nanotechnology and realization of its societal and commercial benefits. All these criteria are necessary for responsible development to occur. Since it is early in the commercialization of nanotechnology, there are still many unknowns and concerns about nanomaterials. Therefore, it is prudent to treat them as potentially hazardous until sufficient toxicology, and exposure data are gathered for nanomaterial-specific hazard and risk assessments. In this emergent period, it is necessary to be clear about the extent of uncertainty and the need for prudent actions.
C1 [Schulte, P. A.; Geraci, C. L.; Murashov, V.; Kuempel, E. D.; Zumwalde, R. D.; Castranova, V.; Hoover, M. D.; Hodson, L.; Martinez, K. F.] NIOSH, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA.
[Martinez, K. F.] Hassett Willis & Co, Washington, DC USA.
RP Schulte, PA (reprint author), NIOSH, Ctr Dis Control & Prevent, 4676 Columbia Pkwy,MS C-14, Cincinnati, OH 45226 USA.
EM pschulte@cdc.gov
NR 160
TC 17
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U1 2
U2 50
PU SPRINGER
PI DORDRECHT
PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
SN 1388-0764
EI 1572-896X
J9 J NANOPART RES
JI J. Nanopart. Res.
PD DEC 7
PY 2013
VL 16
IS 1
AR UNSP 2153
DI 10.1007/s11051-013-2153-9
PG 17
WC Chemistry, Multidisciplinary; Nanoscience & Nanotechnology; Materials
Science, Multidisciplinary
SC Chemistry; Science & Technology - Other Topics; Materials Science
GA 269DU
UT WOS:000328222100001
ER
PT J
AU King, ME
Lu, PJ
O'Halloran, A
Ding, H
Lozier, MJ
AF King, Michael E.
Lu, Peng-jun
O'Halloran, Alissa
Ding, Helen
Lozier, Matthew J.
TI Vaccination Coverage Among Persons with Asthma - United States,
2010-2011 Influenza Season
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Editorial Material
ID ADULTS
C1 [Lozier, Matthew J.] CDC, EIS, Atlanta, GA 30333 USA.
RP Lozier, MJ (reprint author), CDC, EIS, Atlanta, GA 30333 USA.
EM mlozier@cdc.gov
NR 10
TC 8
Z9 9
U1 0
U2 2
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 6
PY 2013
VL 62
IS 48
BP 973
EP 978
PG 6
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 273WT
UT WOS:000328567700001
ER
PT J
AU Rounds, J
Schlegel, J
Lane, T
Higa, J
Kissler, B
Culpepper, W
Williams, I
Hausman, L
AF Rounds, Joshua
Schlegel, Julie
Lane, Tom
Higa, Jeffrey
Kissler, Bonnie
Culpepper, Wright
Williams, Ian
Hausman, Leslie
TI Multistate Outbreak of Salmonella Chester Infections Associated with
Frozen Meals-18 States, 2010
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Editorial Material
C1 [Rounds, Joshua] Minnesota Dept Hlth, Minneapolis, MN 55414 USA.
[Schlegel, Julie] S Carolina Dept Hlth & Environm Control, Columbia, SC 29201 USA.
[Kissler, Bonnie] USDA, Food Safety & Inspect Svc, Washington, DC USA.
[Culpepper, Wright; Williams, Ian; Hausman, Leslie] CDC, Div Foodborne Waterborne & Environm Dis, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA.
RP Hausman, L (reprint author), CDC, Div Foodborne Waterborne & Environm Dis, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA.
EM lhausman@cdc.gov
NR 9
TC 4
Z9 5
U1 0
U2 2
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 6
PY 2013
VL 62
IS 48
BP 979
EP 982
PG 4
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 273WT
UT WOS:000328567700002
ER
PT J
AU Dabbagh, AJ
Dumolard, L
Gacic-Dobo, M
Grant, GB
Reef, SE
AF Dabbagh, Alya J.
Dumolard, Laure
Gacic-Dobo, Marta
Grant, Gavin B.
Reef, Susan E.
TI Rubella and Congenital Rubella Syndrome Control and Elimination - Global
Progress, 2000-2012
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Editorial Material
C1 [Dabbagh, Alya J.; Dumolard, Laure; Gacic-Dobo, Marta] WHO, Dept Immunizat Vaccines & Biol, CH-1211 Geneva, Switzerland.
[Grant, Gavin B.; Reef, Susan E.] CDC, Global Immunizat Div, Ctr Global Hlth, Atlanta, GA 30333 USA.
RP Grant, GB (reprint author), CDC, Global Immunizat Div, Ctr Global Hlth, Atlanta, GA 30333 USA.
EM gbgrant@cdc.gov
NR 7
TC 16
Z9 18
U1 0
U2 1
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 6
PY 2013
VL 62
IS 48
BP 983
EP 986
PG 4
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 273WT
UT WOS:000328567700003
ER
PT J
AU Quest, C
Klos, R
Davis, JP
Canon, AJ
AF Quest, Carol
Klos, Rachel
Davis, Jeffrey P.
Canon, Abbey J.
TI Escherichia coli O157: H7 Outbreak Associated with Seasonal Consumption
of Raw Ground Beef - Wisconsin, December 2012-January 2013
SO MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
LA English
DT Editorial Material
C1 [Canon, Abbey J.] CDC, EIS, Atlanta, GA 30333 USA.
RP Canon, AJ (reprint author), CDC, EIS, Atlanta, GA 30333 USA.
EM acanon@cdc.gov
NR 4
TC 3
Z9 3
U1 0
U2 1
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 0149-2195
EI 1545-861X
J9 MMWR-MORBID MORTAL W
JI MMWR-Morb. Mortal. Wkly. Rep.
PD DEC 6
PY 2013
VL 62
IS 48
BP 987
EP 987
PG 1
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 273WT
UT WOS:000328567700004
ER
PT J
AU Sunderam, S
Kissin, DM
Crawford, S
Anderson, JE
Folger, SG
Jamieson, DJ
Barfield, WD
AF Sunderam, Saswati
Kissin, Dmitry M.
Crawford, Sara
Anderson, John E.
Folger, Suzanne G.
Jamieson, Denise J.
Barfield, Wanda D.
TI Assisted Reproductive Technology Surveillance - United States, 2010
SO MMWR SURVEILLANCE SUMMARIES
LA English
DT Article
ID IN-VITRO FERTILIZATION; INSURANCE MANDATES; EMBRYO-TRANSFER;
BIRTH-DEFECTS; INFERTILITY TREATMENTS; OVULATION STIMULATION; MULTIPLE
GESTATION; PRETERM BIRTH; RISK; PREGNANCIES
AB Problem/Condition: Since the first U. S. infant conceived with Assisted Reproductive Technology (ART) was born in 1981, both the use of advanced technologies to overcome infertility and the number of fertility clinics providing ART services have increased steadily in the United States. ART includes fertility treatments in which both eggs and sperm are handled in the laboratory (i.e., in vitro fertilization [IVF] and related procedures). Women who undergo ART procedures are more likely to deliver multiple-birth infants than those who conceive naturally because more than one embryo might be transferred during a procedure. Multiple births pose substantial risks to both mothers and infants, including pregnancy complications, preterm delivery, and low birthweight infants. This report provides state-specific information on U. S. ART procedures performed in 2010 and compares infant outcomes that occurred in 2010 (resulting from procedures performed in 2009 and 2010) with outcomes for all infants born in the United States in 2010.
Reporting Period Covered: 2010.
Description of System: In 1996, CDC began collecting data on all ART procedures performed in fertility clinics in the United States and U. S. territories, as mandated by the Fertility Clinic Success Rate and Certification Act of 1992 (FCSRCA) (Public Law 102-493). Data are collected through the National ART Surveillance System (NASS), a web-based data collecting system developed by CDC.
Results: In 2010, a total of 147,260 ART procedures performed in 443 U. S. fertility clinics were reported to CDC. These procedures resulted in 47,090 live-birth deliveries and 61,564 infants. The largest numbers of ART procedures were performed among residents of six states: California (18,524), New York (excluding New York City) (14,212), Illinois (10,110), Massachusetts (9,854), New Jersey (8,783), and Texas (8,754). These six states also had the highest number of live-birth deliveries as a result of ART procedures and together accounted for 48.0% of all ART procedures performed, 45.0% of all infants born from ART, and 45.0% of all multiple live-birth deliveries but only 34.0% of all infants born in the United States and U. S. territories. Nationally, the average number of ART procedures performed per 1 million women of reproductive age (15-44 years), which is a proxy indicator of ART use, was 2,331. In 13 states (California, Connecticut, Delaware, Hawaii, Illinois, Maryland, Massachusetts, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island, and Virginia), this proxy measure was higher than the national rate, and in four states (Connecticut, Massachusetts, New Jersey, and New York) and the District of Columbia, it exceeded twice the national rate. Nationally, among cycles in which at least one embryo was transferred, the average number of embryos transferred increased with increasing age (2.0 among women aged <35 years, 2.4 among women aged 35-40 years, and 3.0 among women aged >40 years). Elective single-embryo transfer (eSET) rates decreased with increasing age (10.0% among women aged <35 years, 3.8% among women aged 35-40 years, and 0.6% among women aged >40 years). ESET rates also varied substantially between states (range: 0 to 45.0% among women aged <35 years).
The number of ART births as a percentage of total infants born in the state or territory is considered as another measure of ART use. Overall, ART contributed to 1.5% of U. S. births (range: 0.1% in Guam to 4.8% in Massachusetts) with the highest rates (>3.5% of all infants born) observed in four states (Connecticut, Massachusetts, New Jersey, and New York), and the District of Columbia. The proportion of ART births was <= 2.5% in the remaining states and territories. Infants conceived with ART comprised 20.0% of all multiple-birth infants (range: 0 in Guam to 40.5% in Massachusetts), 19.0% of all twin infants (range: 0 in Guam to 40.0% in Massachusetts), and 33.0% of triplet or higher order infants (range: 0 in several states to 60.0% in Arizona). Among infants conceived with ART, 46.0% were born in multiple deliveries (range: 0 in Guam to 55.4% in Utah), compared with only 3.0% of infants among all births in the general population (range: 1.3% in Guam to 4.7% in Connecticut). A substantial proportion (43.4%) of ART-conceived infants were twin infants, and a smaller proportion (3.0%) were triplets and higher order infants.
Nationally, infants conceived with ART comprised 5.6% of all low birthweight (<2,500 grams) infants (range: 0 in Guam to 16.0% in Massachusetts) and 5.6% of all very low birthweight (<1,500 grams) infants (range: 0 in Guam to 15.8% in Massachusetts). Overall, among ART-conceived infants, 31.6% were low birthweight (range: 22.6% in New Hampshire to 48.2% in Puerto Rico), compared with 8.0% among all infants (range: 5.7% in Alaska to 12.6% in Puerto Rico); 5.6% of ART infants were very low birthweight (range: 1.9% in Maine to 14.3% in Montana), compared with 1.4% among all infants (range: 0.9% in Alaska to 2.3% in the District of Columbia). Finally, ART-conceived infants comprised 4.4% of all infants born preterm (<37 weeks; range: 0 in Guam to 13.3% in Massachusetts) and 4.9% of all infants born very preterm (<32 weeks; range: 0 in Guam to 16.2% in Massachusetts). Overall, among infants conceived with ART, 36.6% were born preterm (range: 23.6% in New Hampshire to 56.8% in Wyoming), compared with 12.0% among all infants born in the general population (range: 8.4% in Vermont to 17.9% in Guam); 6.6% of ART infants were born very preterm (range: 0 in Maine to 14.5% in Puerto Rico), compared with 2.0% among all infants born in the general population (range: 1.3% in Alaska to 3.0% in the District of Columbia).
Interpretation: The percentage of infants conceived with ART varied considerably by state and territory (range: 0.1% to 4.8%). In most states, multiples from ART comprised a substantial proportion of all twin, triplet, and higher-order infants born in the state, and the rates of low birthweight and preterm infants were disproportionately higher among ART infants than in the birth population overall. Even among women aged <35 years, for whom single embryo transfers should be considered (particularly in patients with a favorable prognosis) according to American Society of Reproductive Medicine (ASRM) guidelines, on average, two embryos were transferred per cycle in ART procedures, influencing the overall multiple infant rates in the United States. ART use per population unit was distributed disproportionately in the United States, with only 13 states showing ART use above the national rate, which might suggest barriers to ART services in the remaining states. Of the four states (Illinois, Massachusetts, New Jersey, and Rhode Island) with comprehensive statewide-mandated health insurance coverage for ART procedures (e. g., coverage for at least four cycles of IVF), three states (Illinois, Massachusetts, and New Jersey) also had rates of ART use >1.5 times the national level. This type of mandated insurance has been associated with greater use of ART and might account for the differences observed in other states.
Public Health Actions: Reducing the number of embryos transferred per ART procedure among all age groups and promotion of eSET procedures, when clinically appropriate, is needed to reduce multiple births, including twin births, and related adverse consequences of ART. Improved patient education and counseling on the risks of twins might be useful in reducing twin births because twins account for the majority of multiples. Although ART contributes to increasing rates of multiple births, it does not explain all of the increases, and therefore the possible role of non-ART fertility treatments warrants further study.
C1 [Sunderam, Saswati; Kissin, Dmitry M.; Crawford, Sara; Anderson, John E.; Folger, Suzanne G.; Jamieson, Denise J.; Barfield, Wanda D.] CDC, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USA.
RP Sunderam, S (reprint author), CDC, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USA.
EM zga0@cdc.gov
NR 48
TC 41
Z9 49
U1 0
U2 11
PU CENTER DISEASE CONTROL & PREVENTION
PI ATLANTA
PA MAILSTOP E-90, ATLANTA, GA 30333 USA
SN 1545-8636
J9 MMWR SURVEILL SUMM
JI MMWR Surv. Summ.
PD DEC 6
PY 2013
VL 62
IS 9
BP 1
EP 24
PG 24
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 263OB
UT WOS:000327816800001
PM 24304902
ER
PT J
AU Rimmelzwaan, GF
Katz, JM
AF Rimmelzwaan, Guus F.
Katz, Jacqueline M.
TI Immune responses to infection with H5N1 influenza virus
SO VIRUS RESEARCH
LA English
DT Article
DE Influenza A H5N1 virus; Infection; Immune response
ID CROSS-PROTECTIVE IMMUNITY; TO-PERSON TRANSMISSION; AVIAN-INFLUENZA; A
H5N1; MONOCLONAL-ANTIBODY; SEROLOGIC ASSAYS; CELL RESPONSES; HONG-KONG;
NEUTRALIZING ANTIBODIES; RECEPTOR SPECIFICITY
AB Influenza A H5N1 viruses remain a substantial threat to global public health. In particular, the expanding genetic diversity of H5N1 viruses and the associated risk for human adaptation underscore the importance of better understanding host immune responses that may protect against disease or infection. Although much emphasis has been placed on investigating early virus-host interactions and the induction of innate immune responses, little is known of the consequent adaptive immune response to H5N1 virus infection. In this review, we describe the H5N1 virus-specific and cross-reactive antibody and T cell responses in humans and animal models. Data from limited studies suggest that although initially robust, there is substantial waning of the serum antibody responses in survivors of H5N1 virus infection. Characterization of monoclonal antibodies generated from memory B cells of survivors of H5N1 virus infection has provided an understanding of the fine specificity of the human antibody response to H5N1 virus infection and identified strategies for immunotherapy. Human T cell responses induced by infection with seasonal influenza viruses are directed to relatively conserved internal proteins and cross-react with the H5N1 subtype. A role for T cell-based heterosubtypic immunity against H5N1 viruses is suggested in animal studies. Further studies on adaptive immune responses to H5N1 virus infection in both humans and animals are needed to inform the design of optimal immunological treatment and prevention modalities. Published by Elsevier B.V.
C1 [Rimmelzwaan, Guus F.] Erasmus MC, Virosci Lab, Rotterdam, Netherlands.
[Katz, Jacqueline M.] Ctr Dis Control & Prevent, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA USA.
RP Katz, JM (reprint author), Influenza Div, MS G-16,1600 Clifton Rd NE, Atlanta, GA 30333 USA.
EM JKatz@cdc.gov
NR 103
TC 3
Z9 3
U1 1
U2 16
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0168-1702
EI 1872-7492
J9 VIRUS RES
JI Virus Res.
PD DEC 5
PY 2013
VL 178
IS 1
BP 44
EP 52
DI 10.1016/j.virusres.2013.05.011
PG 9
WC Virology
SC Virology
GA 273GA
UT WOS:000328522100007
PM 23735534
ER
PT J
AU Belser, JA
Tumpey, TM
AF Belser, Jessica A.
Tumpey, Terrence M.
TI H5N1 pathogenesis studies in mammalian models
SO VIRUS RESEARCH
LA English
DT Article
DE Influenza; H5N1; Pathogenesis; Mice; Mammalian; Ferret; Avian influenza
ID INFLUENZA-A-VIRUS; SINGLE-AMINO-ACID; RESPIRATORY-DISTRESS-SYNDROME;
INNATE IMMUNE-RESPONSES; CENTRAL-NERVOUS-SYSTEM; GENE PROTECTS MICE;
VIRAL NS1 PROTEIN; ACUTE LUNG INJURY; HONG-KONG; MOUSE MODEL
AB H5N1 influenza viruses are capable of causing severe disease and death in humans, and represent a potential pandemic subtype should they acquire a transmissible phenotype. Due to the expanding host and geographic range of this virus subtype, there is an urgent need to better understand the contribution of both virus and host responses following H5N1 virus infection to prevent and control human disease. The use of mammalian models, notably the mouse and ferret, has enabled the detailed study of both complex virus-host interactions as well as the contribution of individual viral proteins and point mutations which influence virulence. In this review, we describe the behavior of H5N1 viruses which exhibit high and low virulence in numerous mammalian species, and highlight the contribution of inoculation route to virus pathogenicity. The involvement of host responses as studied in both inbred and outbred mammalian models is discussed. The roles of individual viral gene products and molecular determinants which modulate the severity of H5N1 disease in vivo are presented. This research contributes not only to our understanding of influenza virus pathogenesis, but also identifies novel preventative and therapeutic targets to mitigate the disease burden caused by avian influenza viruses. Published by Elsevier B.V.
C1 [Belser, Jessica A.; Tumpey, Terrence M.] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Influenza Div, Atlanta, GA 30333 USA.
RP Tumpey, TM (reprint author), Influenza Div, MS G-16,1600 Clifton Rd NE, Atlanta, GA 30333 USA.
EM tft9@cdc.gov
NR 223
TC 11
Z9 11
U1 2
U2 15
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0168-1702
EI 1872-7492
J9 VIRUS RES
JI Virus Res.
PD DEC 5
PY 2013
VL 178
IS 1
BP 168
EP 185
DI 10.1016/j.virusres.2013.02.003
PG 18
WC Virology
SC Virology
GA 273GA
UT WOS:000328522100017
PM 23458998
ER
PT J
AU Kulkarni, AD
Jamieson, DJ
Jones, HW
Kissin, DM
Gallo, MF
Macaluso, M
Adashi, EY
AF Kulkarni, Aniket D.
Jamieson, Denise J.
Jones, Howard W., Jr.
Kissin, Dmitry M.
Gallo, Maria F.
Macaluso, Maurizio
Adashi, Eli Y.
TI Fertility Treatments and Multiple Births in the United States
SO NEW ENGLAND JOURNAL OF MEDICINE
LA English
DT Article
ID ASSISTED-REPRODUCTIVE-TECHNOLOGY; SINGLE-EMBRYO TRANSFER; OVULATION
STIMULATION; INSURANCE-COVERAGE; AMERICAN-SOCIETY; PREGNANCIES;
INFERTILITY; OUTCOMES; RATES; NUMBER
AB BackgroundThe advent of fertility treatments has led to an increase in the rate of multiple births in the United States. However, the trends in and magnitude of the contribution of fertility treatments to the increase are uncertain.
MethodsWe derived the rates of multiple births after natural conception from data on distributions of all births from 1962 through 1966 (before fertility treatments were available). Publicly available data on births from 1971 through 2011 were used to determine national multiple birth rates, and data on in vitro fertilization (IVF) from 1997 through 2011 were used to estimate the annual proportion of multiple births that were attributable to IVF and to non-IVF fertility treatments, after adjustment for maternal age. Trends in multiple births were examined starting from 1998, the year when clinical practice guidelines for IVF were developed with an aim toward reducing the incidence of multiple births.
ResultsWe estimated that by 2011, a total of 36% of twin births and 77% of triplet and higher-order births resulted from conception assisted by fertility treatments. The observed incidence of twin births increased by a factor of 1.9 from 1971 to 2009. The incidence of triplet and higher-order births increased by a factor of 6.7 from 1971 to 1998 and decreased by 29% from 1998 to 2011. This decrease coincided with a 70% reduction in the transfer of three or more embryos during IVF (P<0.001) and a 33% decrease in the proportion of triplet and higher-order births attributable to IVF (P<0.001).
ConclusionsOver the past four decades, the increased use of fertility treatments in the United States has been associated with a substantial rise in the rate of multiple births. The rate of triplet and higher-order births has declined over the past decade in the context of a reduction in the transfer of three or more embryos during IVF. (Funded by the Centers for Disease Control and Prevention.)
C1 [Kulkarni, Aniket D.; Jamieson, Denise J.; Kissin, Dmitry M.; Gallo, Maria F.] Ctr Dis Control & Prevent, Womens Hlth & Fertil Branch, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30341 USA.
[Jones, Howard W., Jr.] Johns Hopkins Sch Med, Baltimore, MD USA.
[Jones, Howard W., Jr.] Eastern Virginia Med Sch, Norfolk, VA 23501 USA.
[Macaluso, Maurizio] Cincinnati Childrens Hosp Med Ctr, Div Biostat & Epidemiol, Cincinnati, OH 45229 USA.
[Adashi, Eli Y.] Brown Univ, Warren Alpert Med Sch, Providence, RI 02912 USA.
RP Kulkarni, AD (reprint author), Ctr Dis Control & Prevent, Womens Hlth & Fertil Branch, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, 4770 Buford Hwy NE,Mailstop F-74, Atlanta, GA 30341 USA.
EM eof0@cdc.gov
RI Macaluso, Maurizio/J-2076-2015
OI Macaluso, Maurizio/0000-0002-2977-9690
FU Centers for Disease Control and Prevention
FX Funded by the Centers for Disease Control and Prevention.
NR 41
TC 68
Z9 72
U1 1
U2 12
PU MASSACHUSETTS MEDICAL SOC
PI WALTHAM
PA WALTHAM WOODS CENTER, 860 WINTER ST,, WALTHAM, MA 02451-1413 USA
SN 0028-4793
EI 1533-4406
J9 NEW ENGL J MED
JI N. Engl. J. Med.
PD DEC 5
PY 2013
VL 369
IS 23
BP 2218
EP 2225
DI 10.1056/NEJMoa1301467
PG 8
WC Medicine, General & Internal
SC General & Internal Medicine
GA 263II
UT WOS:000327801100008
PM 24304051
ER
PT J
AU McCarthy, NL
Gee, J
Lin, ND
Thyagarajan, V
Pan, Y
Su, S
Turnbull, B
Chan, KA
Weintraub, E
AF McCarthy, Natalie L.
Gee, Julianne
Lin, Nancy D.
Thyagarajan, Veena
Pan, Yi
Su, Sue
Turnbull, Bruce
Chan, K. Arnold
Weintraub, Eric
TI Evaluating the safety of influenza vaccine using a claims-based health
system
SO VACCINE
LA English
DT Article
DE Vaccine safety; Claims; Influenza; H1N1
ID GUILLAIN-BARRE-SYNDROME; EVENT REPORTING SYSTEM; DATALINK PROJECT;
ADVERSE EVENTS; CHILDREN; SURVEILLANCE; RECEIPT; SIGNAL; H1N1; RISK
AB Introduction: As part of the Centers for Disease Control and Prevention's monitoring and evaluation activities for influenza vaccines, we examined relationships between influenza vaccination and selected outcomes in the 2009-2010 and 2010-2011 influenza seasons in a claims-based data environment.
Methods: We included patients with claims for trivalent influenza vaccine (TIV) and/or 2009 pandemic influenza A H1N1 vaccine (H1N1) during the 2009-2010 and 2010-2011 influenza seasons. Patients were followed for several pre-specified outcomes identified in claims. Seizures and Guillain-Barre Syndrome were selected a priori for medical record confirmation. We estimated incidence rate ratios (IRR) using a self-controlled risk interval (SCRI) or a historical comparison design. Outcomes with elevated IRRs, not selected a priori for medical record review, were further investigated with review of claims histories surrounding the outcome date to determine whether the potential event could be ruled-out or attributed to other causes based on the pattern of medical care.
Results: In the 2009-2010 season, no significant increased risks for outcomes following H1 N1 vaccination were observed. Following TIV administration, the IRR for peripheral nervous system disorders and neuropathy was slightly elevated (1.07,95% Cl: 1.01-1.13). The IRR for anaphylaxis following TIV was 28.55 (95% Cl: 3.57-228.44). After further investigation of claims histories, the majority of potential anaphylaxis cases had additional claims around the time of the event indicating alternate explanatory factors or diagnoses. In the 2010-2011 season following TIV administration, a non-significant elevated IRR for anaphylaxis was observed with no other significant outcome findings.
Conclusion: After claims history review, we ultimately found no increased outcome risk following administration of 998,881 TIV and 538,257 H1N1 vaccine doses in the 2009-2010 season, and 1,158,932 TIV doses in the 2010-2011 season. Published by Elsevier Ltd.
C1 [McCarthy, Natalie L.; Gee, Julianne; Pan, Yi; Weintraub, Eric] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
[Lin, Nancy D.; Turnbull, Bruce] Optum Epidemiol, Waltham, MA 02451 USA.
[Thyagarajan, Veena; Su, Sue] Optum Epidemiol, Ann Arbor, MI 48108 USA.
[Chan, K. Arnold] Natl Taiwan Univ Hosp, Dept Med Res, Taipei, Taiwan.
[Chan, K. Arnold] Natl Taiwan Univ, Coll Med, Taipei 10764, Taiwan.
RP McCarthy, NL (reprint author), CDC, 1600 Clifton Rd,MS-D26, Atlanta, GA 30333 USA.
EM nmccarthy@cdc.gov; dzg2@cdc.gov; nancy.lin@optum.com;
veena.thyagarajan@optum.com; jnu5@cdc.gov; yingsue@yahoo.com;
bruce.turnbull@optum.com; k.a.chan@post.harvard.edu; eiw8@cdc.gov
OI Chan, Kinwei/0000-0001-8161-1986
FU America's Health Insurance Plans; Centers for Disease Control and
Prevention [200-2002-00732]
FX This study was supported by a contract with America's Health Insurance
Plans, funded by the Centers for Disease Control and Prevention
(contract number: 200-2002-00732). Ms. Thyagarajan, Mr. Turnbull and Dr.
Lin are employees of Optum. Dr. Chan and Ms. Su were employees of Optum
at the time this study was conducted. Ms. Gee, Ms. McCarthy, and Mr.
Weintraub are employees of the Centers for Disease Control and
Prevention.
NR 16
TC 5
Z9 5
U1 0
U2 7
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 5
PY 2013
VL 31
IS 50
BP 5975
EP 5982
DI 10.1016/j.vaccine.2013.10.031
PG 8
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 268PA
UT WOS:000328181800009
PM 24148577
ER
PT J
AU Thyagarajan, V
Su, S
Gee, J
Duffy, J
McCarthy, NL
Chan, KA
Weintraub, ES
Lin, ND
AF Thyagarajan, Veena
Su, Sue
Gee, Julianne
Duffy, Jonathan
McCarthy, Natalie L.
Chan, K. Arnold
Weintraub, Eric S.
Lin, Nancy D.
TI Identification of seizures among adults and children following influenza
vaccination using health insurance claims data
SO VACCINE
LA English
DT Article
DE Vaccine safety; Seizure; ICD-9 diagnosis codes; Positive predictive
value; Large electronic healthcare database
ID FEBRILE SEIZURES; SAFETY SURVEILLANCE; RISK; PROJECT; MEASLES; MUMPS;
IMMUNIZATION; CONVULSION; PERTUSSIS; EPILEPSY
AB Introduction: Post-licensure surveillance of adverse events following vaccination or prescription drug use often relies on electronic healthcare data to efficiently detect and evaluate safety signals. The accuracy of seizure-related diagnosis codes in identifying true incident seizure events in vaccine safety studies is influenced by factors such as clinical setting of diagnosis and age. To date, most studies of post-vaccination seizure have focused on pediatric populations. More information is needed on how well seizure can be identified in adults and children using algorithms that rely on electronic healthcare data.
Methods: This validation study was part of a larger safety study of influenza vaccination during the 2009-2010 and 2010-2011 influenza seasons. Children and adults receiving influenza vaccination were drawn from an administrative claims database of a large United States healthcare insurer. Potential seizure events were identified using an algorithm of ICD-9 diagnosis codes associated with an emergency department (ED) visit or hospitalization within pre-specified risk windows following influenza vaccination. Seizure events were confirmed through medical record review. The positive predictive value (PPV) of the algorithm was calculated within each diagnostic setting and stratified by age group, ICD-9 code group, and sex.
Results: Review confirmed 113 out of 176 potential seizure events. The PPVs were higher in the ED setting (93.9%) than in the inpatient setting (38.3%). The PPVs by age varied within the ED setting (98.2% in <7 years, 76.9% in 7-24 years, 92.3% in >= 25 years) and within the inpatient setting (64.7% in <7 years, 33.3% in 7-24 years, 32.3% in >= 25 years).
Conclusions: Our algorithm for identification of seizure events using claims data had a high level of accuracy in the emergency department setting in young children and older adults and a lower, but acceptable, level of accuracy in older children and young adults. (C) 2013 Elsevier Ltd. All rights reserved.
C1 [Thyagarajan, Veena; Su, Sue] Optum Epidemiol, Ann Arbor, MI 48108 USA.
[Gee, Julianne; Duffy, Jonathan; McCarthy, Natalie L.; Weintraub, Eric S.] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA 30333 USA.
[Chan, K. Arnold] Natl Taiwan Univ Hosp, Dept Med Res, Taipei, Taiwan.
[Chan, K. Arnold] Natl Taiwan Univ, Coll Med, Taipei 10764, Taiwan.
[Lin, Nancy D.] Optum Epidemiol, Waltham, MA 02451 USA.
RP Thyagarajan, V (reprint author), Optum Epidemiol, 315 E Eisenhower Pkwy Suite 305, Ann Arbor, MI 48108 USA.
EM veena.thyagarajan@optum.com; dzg2@cdc.gov; jduffy@cdc.gov; gvz7@cdc.gov;
k.a.chan@post.harvard.edu; eiw8@cdc.gov; nancy.lin@optum.com
OI Chan, Kinwei/0000-0001-8161-1986
FU Centers for Disease Control and Prevention [200-2002-00732]
FX This study was conducted by Optum Epidemiology and sponsored through a
subcontract with America's Health Insurance Plans (AHIP) under contract
number 200-2002-00732 from the Centers for Disease Control and
Prevention. The findings and conclusions in this report are those of the
authors and do not necessarily represent the official position of the
Centers for Disease Control and Prevention.
NR 25
TC 0
Z9 0
U1 0
U2 6
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 5
PY 2013
VL 31
IS 50
BP 5997
EP 6002
DI 10.1016/j.vaccine.2013.10.026
PG 6
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 268PA
UT WOS:000328181800012
PM 24148576
ER
PT J
AU Cho, BH
Stoecker, C
Link-Gelles, R
Moore, MR
AF Cho, Bo-Hyun
Stoecker, Charles
Link-Gelles, Ruth
Moore, Matthew R.
TI Cost-effectiveness of administering 13-valent pneumococcal conjugate
vaccine in addition to 23-valent pneumococcal polysaccharide vaccine to
adults with immunocompromising conditions
SO VACCINE
LA English
DT Article
DE PCV13; Incremental cost-effectiveness; lmmunocompromised adults
ID HIV-INFECTED ADULTS; UNITED-STATES; DIALYSIS PATIENTS; DISEASE; IMPACT;
TRIAL; PNEUMONIA; OLDER; TRANSPLANTATION; IMMUNIZATION
AB Background: In June, 2012 a single dose of 13-valent pneumococcal conjugate vaccine (PCV13) was added to the recommendation for immunocompromised adults who were previously recommended to receive only 23-valent pneumococcal polysaccharide vaccine (PPSV23). PCV13 may be more effective, though it covers fewer disease-causing strains.
Objective: We examined the incremental cost-effectiveness of adding one dose of PCV13 to the pre-2012 recommendation of PPSV23 for adults with 4 immunocompromising conditions who are at increased risk of pneumococcal disease: HIV/AIDS, hematologic cancer, solid organ transplants, and end stage renal disease.
Methods: We used a probabilistic model following a single cohort of 302,397 immunocompromised adults. We used vaccination coverage and disease incidence data specific to each immunocompromising condition. Assumptions about PPSV23 and PCV13 vaccine effectiveness were based on two randomized controlled trials and several observational studies conducted among HIV-infected adults. Because no such studies have been conducted among other immunocompromised populations, we made further assumptions about the relative vaccine effectiveness in those groups. Cost-effectiveness ratios were determined for each condition and for all 4 groups in total.
Results: Our model indicated that adding one dose of PCV13 to adults in the United States with 4 immunocompromising conditions would cost $16 million (in 2009$) but provide off-setting savings of $21 million per cohort from the societal perspective. These savings come largely from decreased medical costs among adults with end stage renal disease. This dose of PCV13 would prevent 57 cases of invasive pneumococcal disease, 619 cases of hospitalized all-cause pneumonia, avert 93 deaths, and save 1360 quality adjusted life years per cohort.
Conclusion: The addition of one dose of PCVI3 to the previously recommended PPSV23 doses for adults with selected immunocompromised conditions potentially reduces both disease and costs. (C) 2013 Elsevier Ltd. All rights reserved.
C1 [Cho, Bo-Hyun; Link-Gelles, Ruth; Moore, Matthew R.] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Atlanta, GA USA.
[Stoecker, Charles] Tulane Univ, Sch Publ Hlth & Trop Med, Dept Global Hlth Syst & Dev, New Orleans, LA 70112 USA.
RP Stoecker, C (reprint author), Tulane Univ, Sch Publ Hlth & Trop Med, Dept Global Hlth Syst & Dev, 1440 Canal St,Suite 1923, New Orleans, LA 70112 USA.
EM cfstoecker@tulane.edu
NR 47
TC 12
Z9 13
U1 1
U2 7
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 5
PY 2013
VL 31
IS 50
BP 6011
EP 6021
DI 10.1016/j.vaccine.2013.10.024
PG 11
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 268PA
UT WOS:000328181800014
PM 24148572
ER
PT J
AU Ruckart, PZ
Bove, FJ
Maslia, M
AF Ruckart, Perri Zeitz
Bove, Frank J.
Maslia, Morris
TI Evaluation of exposure to contaminated drinking water and specific birth
defects and childhood cancers at Marine Corps Base Camp Lejeune, North
Carolina: a case-control study
SO ENVIRONMENTAL HEALTH
LA English
DT Article
DE Neural tube defects; Childhood cancers; Environmental epidemiology;
Trichloroethylene; Water
ID MATERNAL OCCUPATIONAL-EXPOSURE; NEURAL-TUBE DEFECTS;
CONGENITAL-MALFORMATIONS; CHLORINATED SOLVENTS; ORGANIC-SOLVENTS; ORAL
CLEFTS; RISK; LEUKEMIA; PREGNANCY; TETRACHLOROETHYLENE
AB Background: Drinking water supplies at Marine Corps Base Camp Lejeune were contaminated with trichloroethylene, tetrachloroethylene, benzene, vinyl chloride and trans-1,2-dichloroethylene during 1968 through 1985.
Methods: We conducted a case control study to determine if children born during 1968-1985 to mothers with residential exposure to contaminated drinking water at Camp Lejeune during pregnancy were more likely to have childhood hematopoietic cancers, neural tube defects (NTDs), or oral clefts. For cancers, exposures during the first year of life were also evaluated. Cases and controls were identified through a survey of parents residing on base during pregnancy and confirmed by medical records. Controls were randomly sampled from surveyed participants who had a live birth without a major birth defect or childhood cancer. Groundwater contaminant fate and transport and distribution system models provided estimates of monthly levels of drinking water contaminants at mothers' residences. Magnitude of odds ratios (ORs) was used to assess associations. Confidence intervals (CIs) were used to indicate precision of ORs. We evaluated parental characteristics and pregnancy history to assess potential confounding.
Results: Confounding was negligible so unadjusted results were presented. For NTDs and average 1st trimester exposures, ORs for any benzene exposure and for trichloroethylene above 5 parts per billion were 4.1 (95% CI: 1.4-12.0) and 2.4 (95% CI: 0.6-9.6), respectively. For trichloroethylene, a monotonic exposure response relationship was observed. For childhood cancers and average 1st trimester exposures, ORs for any tetrachloroethylene exposure and any vinyl chloride exposure were 1.6 (95% CI: 0.5-4.8), and 1.6 (95% CI: 0.5-4.7), respectively. The study found no evidence suggesting any other associations between outcomes and exposures.
Conclusion: Although CIs were wide, ORs suggested associations between drinking water contaminants and NTDs. ORs suggested weaker associations with childhood hematopoietic cancers.
C1 [Ruckart, Perri Zeitz; Bove, Frank J.] Agcy Tox Subst & Dis Registry, Div Toxicol & Human Hlth Sci, Atlanta, GA 30341 USA.
[Maslia, Morris] Agcy Tox Subst & Dis Registry, Div Community Hlth Invest, Atlanta, GA 30341 USA.
RP Ruckart, PZ (reprint author), Agcy Tox Subst & Dis Registry, Div Toxicol & Human Hlth Sci, 4770 Buford Highway,MS F-58, Atlanta, GA 30341 USA.
EM pruckart@cdc.gov
NR 38
TC 13
Z9 16
U1 2
U2 15
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1476-069X
J9 ENVIRON HEALTH-GLOB
JI Environ. Health
PD DEC 4
PY 2013
VL 12
AR 104
DI 10.1186/1476-069X-12-104
PG 10
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA 297VT
UT WOS:000330283900001
PM 24304547
ER
PT J
AU Nyendak, MR
Park, B
Null, MD
Baseke, J
Swarbrick, G
Mayanja-Kizza, H
Nsereko, M
Johnson, DF
Gitta, P
Okwera, A
Goldberg, S
Bozeman, L
Johnson, JL
Boom, WH
Lewinsohn, DA
Lewinsohn, DM
AF Nyendak, Melissa R.
Park, Byung
Null, Megan D.
Baseke, Joy
Swarbrick, Gwendolyn
Mayanja-Kizza, Harriet
Nsereko, Mary
Johnson, Denise F.
Gitta, Phineas
Okwera, Alphonse
Goldberg, Stefan
Bozeman, Lorna
Johnson, John L.
Boom, W. Henry
Lewinsohn, Deborah A.
Lewinsohn, David M.
CA TB Res Unit
TB Trials Consortium
TI Mycobacterium tuberculosis Specific CD8(+) T Cells Rapidly Decline with
Antituberculosis Treatment
SO PLOS ONE
LA English
DT Article
ID INTERFERON-GAMMA RESPONSES; PULMONARY TUBERCULOSIS; IFN-GAMMA; ANTIGEN;
INFECTION; MALNUTRITION; INDIVIDUALS; BIOMARKERS; SIGNATURE; REVERSION
AB Rationale: Biomarkers associated with response to therapy in tuberculosis could have broad clinical utility. We postulated that the frequency of Mycobacterium tuberculosis (Mtb) specific CD8(+) T cells, by virtue of detecting intracellular infection, could be a surrogate marker of response to therapy and would decrease during effective antituberculosis treatment.
Objectives: We sought to determine the relationship of Mtb specific CD4(+) T cells and CD8(+) T cells with duration of antituberculosis treatment.
Materials and Methods: We performed a prospective cohort study, enrolling between June 2008 and August 2010, of HIV-uninfected Ugandan adults (n = 50) with acid-fast bacillus smear-positive, culture confirmed pulmonary TB at the onset of antituberculosis treatment and the Mtb specific CD4(+) and CD8(+) T cell responses to ESAT-6 and CFP-10 were measured by IFN-gamma ELISPOT at enrollment, week 8 and 24.
Results: There was a significant difference in the Mtb specific CD8(+) T response, but not the CD4(+) T cell response, over 24 weeks of antituberculosis treatment (p<0.0001), with an early difference observed at 8 weeks of therapy (p = 0.023). At 24 weeks, the estimated Mtb specific CD8(+) T cell response decreased by 58%. In contrast, there was no significant difference in the Mtb specific CD4(+) T cell during the treatment. The Mtb specific CD4(+) T cell response, but not the CD8(+) response, was negatively impacted by the body mass index.
Conclusions: Our data provide evidence that the Mtb specific CD8(+) T cell response declines with antituberculosis treatment and could be a surrogate marker of response to therapy. Additional research is needed to determine if the Mtb specific CD8(+) T cell response can detect early treatment failure, relapse, or to predict disease progression.
C1 [Nyendak, Melissa R.; Lewinsohn, David M.] Oregon Hlth & Sci Univ, Dept Med, Portland, OR 97201 USA.
[Park, Byung] Oregon Hlth & Sci Univ, Dept Publ Hlth & Prevent Med, Portland, OR 97201 USA.
[Null, Megan D.; Lewinsohn, Deborah A.] Oregon Hlth & Sci Univ, Dept Pediat, Portland, OR 97201 USA.
[Baseke, Joy; Mayanja-Kizza, Harriet; Nsereko, Mary; Gitta, Phineas; Okwera, Alphonse; Johnson, John L.; Boom, W. Henry] Uganda Case Western Reserve Univ, Res Collaborat, Kampala, Uganda.
[Swarbrick, Gwendolyn; Lewinsohn, David M.] Portland VA Med Ctr, Dept Med, Portland, OR USA.
[Mayanja-Kizza, Harriet] Makerere Univ, Coll Hlth Sci, Dept Med, Kampala, Uganda.
[Johnson, Denise F.; Johnson, John L.; Boom, W. Henry] Case Western Reserve Univ, TB Res Unit, Cleveland, OH 44106 USA.
[Goldberg, Stefan; Bozeman, Lorna] Ctr Dis Control & Prevent, TB Trials Consortium, Natl Ctr HIV AIDS Viral Hepatitis & TB Prevent, Div TB Eliminat, Atlanta, GA USA.
RP Nyendak, MR (reprint author), Oregon Hlth & Sci Univ, Dept Med, Portland, OR 97201 USA.
EM nyendakm@ohsu.edu; lewinsod@ohsu.edu
RI Lewinsohn, David/I-4936-2013
OI Mayanja-Kizza, Harriet/0000-0002-9297-6208; Lewinsohn,
David/0000-0001-9906-9494
FU NIH [HHSN266200400081C, HHSN272200900053C]; National Center for Research
Resources [KL2RR024141]; VA Merit Review Grant; Portland VA Medical
Center; Tuberculosis Research Unit at Case Western Reserve University;
United States National Institute of Allergy and Infectious Diseases,
National Institutes of Health and Human Services
[HHSN266200700022C/NO1-AI-70022]; US Government Division of Tuberculosis
Elimination, National Center for HIV, Viral Hepatitis, STD, and TB
Prevention, Centers for Disease Control and Prevention (CDC)
[200-2009-32598]
FX This work was supported in part by the following agency and institutes:
NIH grants HHSN266200400081C and HHSN272200900053C, The National Center
for Research Resources KL2RR024141, VA Merit Review Grant and the
Portland VA Medical Center. This work was also supported by the
Tuberculosis Research Unit at Case Western Reserve University,
established with funds from the United States National Institute of
Allergy and Infectious Diseases, National Institutes of Health and Human
Services, under contract number HHSN266200700022C/NO1-AI-70022 and the
Tuberculosis Trials Consortium sponsored by the US Government Division
of Tuberculosis Elimination, National Center for HIV, Viral Hepatitis,
STD, and TB Prevention, Centers for Disease Control and Prevention
(CDC), contract number 200-2009-32598. The findings and conclusions in
this report are those of the authors and do not necessarily represent
the views of the CDC or the Agency for Toxic Substances and Disease
Registry. The funders had no role in study design, data collection and
analysis, decision to publish, or preparation of the manuscript.
NR 44
TC 15
Z9 15
U1 0
U2 3
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 4
PY 2013
VL 8
IS 12
AR e81564
DI 10.1371/journal.pone.0081564
PG 10
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 265KD
UT WOS:000327949300095
PM 24324704
ER
PT J
AU Hales, CM
Harpaz, R
Joesoef, MR
Bialek, SR
AF Hales, Craig M.
Harpaz, Rafael
Joesoef, M. Riduan
Bialek, Stephanie R.
TI Examination of Links Between Herpes Zoster Incidence and Childhood
Varicella Vaccination
SO ANNALS OF INTERNAL MEDICINE
LA English
DT Article
ID UNITED-STATES; RISK-FACTORS; ADMINISTRATIVE DATABASE; COMPLICATION
RATES; VIRUS-INFECTIONS; OLDER-ADULTS; EPIDEMIOLOGY; SHINGLES;
CHICKENPOX; EXPOSURE
AB Background: Introduction of a universal varicella vaccine program for U.S. children in 1996 sparked concern that less-frequent exposure to varicella would decrease external boosting of immunity to varicella zoster virus and thereby increase incidence of herpes zoster (HZ).
Objective: To determine whether the varicella vaccination program has influenced trends in HZ incidence in the U.S. population older than 65 years.
Design: Retrospective study of Medicare claims.
Setting: Medicare, 1992 through 2010.
Participants: 2 848 765 beneficiaries older than 65 years.
Measurements: Annual HZ incidence from 1992 through 2010; rate ratios (RRs) for HZ incidence by age, sex, and race or ethnicity; and state-level varicella vaccination coverage.
Results: 281 317 incident cases of HZ occurred. Age- and sex-standardized HZ incidence increased 39% from 10.0 per 1000 person-years in 1992 to 13.9 per 1000 person-years in 2010 with no evidence of a statistically significant change in the rate of in-crease after introduction of the varicella vaccination program. Before introduction of this program, HZ incidence was higher in women (RR, 1.21 [95% CI, 1.19 to 1.24]) than men and was lower in black persons (RR, 0.51 [CI, 0.48 to 0.53]) and Hispanic persons (RR, 0.76 [CI, 0.72 to 0.81]) than white persons. In a model adjusted for sex, age, and calendar year from 1997 to 2010, HZ incidence did not vary by state varicella vaccination coverage (RR, 0.9998 [CI, 0.9993 to 1.0003]).
Limitation: Uncertain level and consistency of health-seeking behavior and access and uncertain accuracy of disease coding.
Conclusion: Age- specific HZ incidence increased in the U.S. population older than 65 years even before implementation of the childhood varicella vaccination program. Introduction and widespread use of the vaccine did not seem to affect this increase. This information is reassuring for countries considering universal varicella vaccination.
C1 [Hales, Craig M.; Harpaz, Rafael; Joesoef, M. Riduan; Bialek, Stephanie R.] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
RP Hales, CM (reprint author), Ctr Dis Control & Prevent, Div Viral Dis, Natl Ctr Immunizat & Resp Dis, 1600 Clifton Rd NE,Mail Stop A-34, Atlanta, GA 30333 USA.
EM chales@cdc.gov
NR 49
TC 34
Z9 36
U1 6
U2 13
PU AMER COLL PHYSICIANS
PI PHILADELPHIA
PA INDEPENDENCE MALL WEST 6TH AND RACE ST, PHILADELPHIA, PA 19106-1572 USA
SN 0003-4819
EI 1539-3704
J9 ANN INTERN MED
JI Ann. Intern. Med.
PD DEC 3
PY 2013
VL 159
IS 11
BP 739
EP +
DI 10.7326/0003-4819-159-11-201312030-00006
PG 13
WC Medicine, General & Internal
SC General & Internal Medicine
GA 276EN
UT WOS:000328731000003
PM 24297190
ER
PT J
AU Khabbaz, RF
AF Khabbaz, Rima F.
TI Still Learning From SARS
SO ANNALS OF INTERNAL MEDICINE
LA English
DT Editorial Material
ID ACUTE RESPIRATORY SYNDROME; CORONAVIRUS; INFECTION; OUTBREAK
C1 Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
RP Khabbaz, RF (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd,Mailstop D12, Atlanta, GA 30333 USA.
EM rfk1@cdc.gov
NR 10
TC 3
Z9 3
U1 0
U2 3
PU AMER COLL PHYSICIANS
PI PHILADELPHIA
PA INDEPENDENCE MALL WEST 6TH AND RACE ST, PHILADELPHIA, PA 19106-1572 USA
SN 0003-4819
EI 1539-3704
J9 ANN INTERN MED
JI Ann. Intern. Med.
PD DEC 3
PY 2013
VL 159
IS 11
BP 780
EP +
DI 10.7326/0003-4819-159-11-201312030-00011
PG 3
WC Medicine, General & Internal
SC General & Internal Medicine
GA 276EN
UT WOS:000328731000008
PM 24297195
ER
PT J
AU Carignan, CC
Heiger-Bernays, W
McClean, MD
Roberts, SC
Stapleton, HM
Sjodin, A
Webster, TF
AF Carignan, Courtney C.
Heiger-Bernays, Wendy
McClean, Michael D.
Roberts, Simon C.
Stapleton, Heather M.
Sjoedin, Andreas
Webster, Thomas F.
TI Flame Retardant Exposure among Collegiate United States Gymnasts
SO ENVIRONMENTAL SCIENCE & TECHNOLOGY
LA English
DT Article
ID POLYBROMINATED DIPHENYL ETHERS; IN-HOUSE DUST;
POLYCHLORINATED-BIPHENYLS; SERUM CONCENTRATIONS; BREAST-MILK; PBDES;
ASSOCIATIONS; ENVIRONMENT; POPULATION; PREGNANCY
AB Gymnastics training facilities contain large volumes of polyurethane foam, a material that often contains additive flame retardants such as PentaBDE. While investigations of human exposure to flame retardants have focused on the general population, potentially higher than background exposures may occur in gymnasts and certain occupational groups. Our objectives were to compare PentaBDE body burden among gymnasts to the general United States population and characterize flame retardants levels in gym equipment, air, and dust. We recruited 11 collegiate female gymnasts (ages 18-22) from one gym in the eastern United States. The geometric mean (GM) concentration of BDE-153 in gymnast sera (32.5 ng/g lipid) was 4-6.5 times higher than in the general United States population groups. Median concentrations of PentaBDE, TBB, and TBPH in paired handwipe samples were 2-3 times higher after practice compared to before, indicating the gymnasts contacted these flame retardants during practice. GM concentrations of PentaBDE, TBB, and TBPH were 1-3 orders of magnitude higher in gym air and dust than in residences. Our findings suggest that these collegiate gymnasts experienced higher exposures to PentaBDE flame retardants compared to the general United States population and that gymnasts may also have increased exposure to other additive flame retardants used in polyurethane foam such as TBB and TBPH.
C1 [Carignan, Courtney C.; Heiger-Bernays, Wendy; McClean, Michael D.; Webster, Thomas F.] Boston Univ, Sch Publ Hlth, Dept Environm Hlth, Boston, MA 02118 USA.
[Roberts, Simon C.; Stapleton, Heather M.] Duke Univ, Nicholas Sch Environm, Durham, NC 27708 USA.
[Sjoedin, Andreas] Ctr Dis Control & Prevent, Div Sci Lab, Natl Ctr Environm Hlth, Atlanta, GA 30333 USA.
RP Carignan, CC (reprint author), Dartmouth Coll, 78 Coll St HB6044, Hanover, NH 03755 USA.
EM courtney.c.carignan@dartmouth.edu
RI Sjodin, Andreas/F-2464-2010; McClean, Michael/J-2934-2015
FU National Institute of Environmental Health Sciences (NIEHS)
[T32ES014562, R01ES015829, R01ES016099]
FX We thank the study participants, gyms, and coaches, as well as Scott
Harris and Kelly Hartnett. We thank Jennifer Ames, Ashley Miller, and
Brittany Weldon for their assistance with the sampling effort and thank
Adam Carignan for the TOC artwork. This research was supported in part
by grants T32ES014562 (CC), R01ES015829, and R01ES016099 (HS) from the
National Institute of Environmental Health Sciences (NIEHS). The content
is solely the responsibility of the authors and does not necessarily
represent the official position of the Centers for Disease Control and
Prevention or the NIEHS.
NR 38
TC 23
Z9 24
U1 2
U2 45
PU AMER CHEMICAL SOC
PI WASHINGTON
PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
SN 0013-936X
EI 1520-5851
J9 ENVIRON SCI TECHNOL
JI Environ. Sci. Technol.
PD DEC 3
PY 2013
VL 47
IS 23
BP 13848
EP 13856
DI 10.1021/es40378681
PG 9
WC Engineering, Environmental; Environmental Sciences
SC Engineering; Environmental Sciences & Ecology
GA 266CH
UT WOS:000327999400079
PM 24195753
ER
PT J
AU Kuzmina, NA
Lemey, P
Kuzmin, IV
Mayes, BC
Ellison, JA
Orciari, LA
Hightower, D
Taylor, ST
Rupprecht, CE
AF Kuzmina, Natalia A.
Lemey, Philippe
Kuzmin, Ivan V.
Mayes, Bonny C.
Ellison, James A.
Orciari, Lillian A.
Hightower, Dillon
Taylor, Steven T.
Rupprecht, Charles E.
TI The Phylogeography and Spatiotemporal Spread of South-Central Skunk
Rabies Virus
SO PLOS ONE
LA English
DT Article
ID MOLECULAR EPIDEMIOLOGY; STRIPED SKUNKS; POPULATION-DYNAMICS;
NORTH-AMERICA; SELECTION; EPIZOOTIOLOGY; MUTATIONS; EVOLUTION;
EXPANSION; INFERENCE
AB The south-central skunk rabies virus (SCSK) is the most broadly distributed terrestrial viral lineage in North America. Skunk rabies has not been efficiently targeted by oral vaccination campaigns and represents a natural system of pathogen invasion, yielding insights to rabies emergence. In the present study we reconstructed spatiotemporal spread of SCSK in the whole territory of its circulation using a combination of Bayesian methods. The analysis based on 241 glycoprotein gene sequences demonstrated that SCSK is much more divergent phylogenetically than was appreciated previously. According to our analyses the SCSK originated in the territory of Texas similar to 170 years ago, and spread geographically during the following decades. The wavefront velocity in the northward direction was significantly greater than in the eastward and westward directions. Rivers (except the Mississippi River and Rio Grande River) did not constitute significant barriers for epizootic spread, in contrast to deserts and mountains. The mean dispersal rate of skunk rabies was lower than that of the raccoon and fox rabies. Viral lineages circulate in their areas with limited evidence of geographic spread during decades. However, spatiotemporal reconstruction shows that after a long period of stability the dispersal rate and wavefront velocity of SCSK are increasing. Our results indicate that there is a need to develop control measures for SCSK, and suggest how such measure can be implemented most efficiently. Our approach can be extrapolated to other rabies reservoirs and used as a tool for investigation of epizootic patterns and planning interventions towards disease elimination.
C1 [Kuzmina, Natalia A.; Kuzmin, Ivan V.; Ellison, James A.; Orciari, Lillian A.; Hightower, Dillon; Taylor, Steven T.; Rupprecht, Charles E.] Ctr Dis Control & Prevent, Rabies Program, Div High Consequence Pathogens & Pathol, Atlanta, GA 30333 USA.
[Lemey, Philippe] Katholieke Univ Leuven, Dept Microbiol & Immunol, Louvain, Belgium.
[Mayes, Bonny C.] Texas Dept State Hlth Serv, Zoonosis Control Branch, Austin, TX USA.
[Rupprecht, Charles E.] Ross Univ, Sch Vet Med, Dept Epidemiol & Publ Hlth, Basseterre, St Kitts, W Ind Assoc St.
RP Kuzmina, NA (reprint author), Ctr Dis Control & Prevent, Rabies Program, Div High Consequence Pathogens & Pathol, Atlanta, GA 30333 USA.
EM natakuzmina@yandex.ru
FU European Union [278433-PREDEMICS]; ERC [260864]
FX PL acknowledges funding from the European Union Seventh Framework
Programme [FP7/2007-2013] under Grant Agreement no. 278433-PREDEMICS and
ERC Grant agreement no. 260864. The funders had no role in study design,
data collection and analysis, decision to publish, or preparation of the
manuscript.
NR 52
TC 5
Z9 5
U1 1
U2 23
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 3
PY 2013
VL 8
IS 12
AR e82348
DI 10.1371/journal.pone.0082348
PG 11
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 265JR
UT WOS:000327947800094
PM 24312657
ER
PT J
AU McCarthy, NL
Irving, S
Donahue, JG
Weintraub, E
Gee, J
Belongia, E
Baggs, J
AF McCarthy, Natalie L.
Irving, Stephanie
Donahue, James G.
Weintraub, Eric
Gee, Julianne
Belongia, Edward
Baggs, James
TI Vaccination coverage levels among children enrolled in the Vaccine
Safety Datalink
SO VACCINE
LA English
DT Article
DE Vaccine; Vaccine coverage; Vaccine Safety Datalink
ID AGED 19-35 MONTHS; UNITED-STATES; PARENTAL REFUSAL; HEALTH-INSURANCE;
TIMELINESS; EXEMPTIONS; MORBIDITY; MORTALITY; INFECTION; SHORTAGES
AB Introduction: The Vaccine Safety Datalink (VSD) is a collaborative project whose infrastructure provides comprehensive medical and immunization histories for more than 9 million adults and children annually, a predominantly insured population. This study provides the coverage rates of recommended vaccines among children 19-35 months in the VSD from 2005 through 2010. We examine the consistency in vaccine coverage levels, detect possible trends, and evaluate any effect of vaccine shortages on coverage in the VSD.
Methods: We included data from all 10 VSD sites, and examined each year independently. Coverage rates were defined as the percentage of children in the VSD aged 19, 24, or 35 months in a given study year who had received the specified Advisory Committee on Immunization Practices (ACIP) recommended vaccine(s).
Results: We assessed coverage on 658,154 children. The overall coverage rate for children receiving all of the specified ACIP recommended vaccines was 73%, 80%, and 78% at ages 19, 24, and 35 months respectively. The range of coverage across all ages and years was 95-97% for polio vaccine, 91-97%, for MMR vaccine, 94-97% for HepB vaccine, 81-95% for DTaP vaccine, 90-95% for varicella vaccine, 66-91% for PCV, and 93-98% for Hib vaccine. Coverage rates of 4 or more doses of PCV were relatively low in 2005 possibly due to a vaccine shortage, and increased sharply in 2007. Hib vaccine coverage was relatively stable among all ages until 2009 when rates declined among children aged 19 and 24 months also during a vaccine shortage.
Conclusions: Vaccine coverage in the VSD is high, but there is a decline from 2005 to 2010. The results of this study provide benchmark data for future studies, and describe how vaccine supply shortages and resulting changes in ACIP recommendations may have affected vaccine coverage rates in the VSD. Published by Elsevier Ltd.
C1 [McCarthy, Natalie L.; Weintraub, Eric; Gee, Julianne; Baggs, James] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
[Irving, Stephanie; Donahue, James G.; Belongia, Edward] Marshfield Clin Fdn Med Res & Educ, Marshfield, WI 54449 USA.
RP McCarthy, NL (reprint author), CDC, 1600 Clifton Rd,MS D26, Atlanta, GA 30333 USA.
EM gvz7@cdc.gov
OI Irving, Stephanie/0000-0001-7437-6797; Baggs, James/0000-0003-0757-4683
FU Vaccine Safety Datalink contract; America's Health Insurance Plans;
Centers for Disease Control and Prevention
FX This study was supported by the Vaccine Safety Datalink contract with
America's Health Insurance Plans, funded by the Centers for Disease
Control and Prevention. Thanks to the following VSD collaborators for
data management and editorial assistance: Roger Baxter, Robert A.
Bednarczyk, Matthew F. Daley, Lisa Jackson, Nicola Klein, Grace Lee,
Marlene Lugg, Cynthia Nakasato, Saad B. Omer, Mark M. Schmidt, and
VinuthaVijayadeva.
NR 40
TC 4
Z9 4
U1 1
U2 6
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
EI 1873-2518
J9 VACCINE
JI Vaccine
PD DEC 2
PY 2013
VL 31
IS 49
BP 5822
EP 5826
DI 10.1016/j.vaccine.2013.10.011
PG 5
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 274GW
UT WOS:000328595800006
PM 24135576
ER
PT J
AU Mendeloff, J
D'Alessandro, M
Liu, HS
Steiner, E
Kopsic, J
Burns, R
AF Mendeloff, John
D'Alessandro, Maryann
Liu, Hangsheng
Steiner, Elizabeth
Kopsic, Jessica
Burns, Rachel
TI Using OSHA inspection data to analyze respirator protection program
compliance
SO MONTHLY LABOR REVIEW
LA English
DT Article
AB Several million American workers wear respirators on a regular basis, and the Occupational Safety and Health Administration (OSHA) requires that nonagricultural firms have a respiratory protection program. This article uses the OSHA inspection data base to examine all inspections in manufacturing in 47 states from 1999 through 2006; the examination starts with 1999 because an expanded OSHA respiratory program standard became effective in late 1998. The article identifies all inspections and all establishments at which respiratory protection (RP) violations were cited, and it compares the prevalence of violations by industry with the prevalence reported in a recent Bureau of Labor Statistics survey of respirator use. Multivariate analyses are used to identify the roles of industry, establishment size, union status, and employee participation in the inspection on noncompliance at the inspection level and for repeated inspections at the same establishment. The authors find that the pattern of noncompliance across industries mostly mirrors the survey findings about the prevalence of requirements for respirator use, although the chemical industry has fewer violations than expected. The probability of citing an RP violation is similar across establishment size categories, except for a large drop for establishments with over 200 workers. The presence of a worker accompanying the inspector increases the probability that a respiratory program violation will be cited; the presence of a union slightly decreases it.
C1 [Mendeloff, John] Univ Pittsburgh, Pittsburgh, PA 15260 USA.
[Mendeloff, John] RAND Corp, Ctr Hlth & Safety Workpl, Santa Monica, CA 90406 USA.
[D'Alessandro, Maryann] Ctr Dis Control & Prevent, Natl Personal Protect Technol Lab, Atlanta, GA 30333 USA.
[Liu, Hangsheng; Steiner, Elizabeth; Burns, Rachel] RAND Corp, Santa Monica, CA 90406 USA.
[Kopsic, Jessica] MDRC, New York, NY USA.
RP Mendeloff, J (reprint author), Univ Pittsburgh, Pittsburgh, PA 15260 USA.
EM jmendel@rand.org; mdalessandro@cdc.gov; Hangsheng_Liu@rand.org;
Elizabeth_Steiner@rand.org; Jessica.kopsic@gmail.com;
Rachel_Burns@rand.org
FU National Personal Protective Technology Laboratory of the National
Institute of Occupational Safety and Health; RAND Corporation Center for
Health and Safety in the Workplace
FX This study was supported by the National Personal Protective Technology
Laboratory of the National Institute of Occupational Safety and Health
through a contract with the RAND Corporation Center for Health and
Safety in the Workplace. Douglas Landsittel of NPPTL provided many
helpful comments.
NR 15
TC 0
Z9 1
U1 0
U2 0
PU LEGAL BOOKS DEPOT
PI LOS ANGELES
PA PO BOX 27789, LOS ANGELES, CA 90027 USA
SN 0098-1818
J9 MON LABOR REV
JI Mon. Labor Rev.
PD DEC 2
PY 2013
BP 1
EP 27
PG 27
WC Industrial Relations & Labor
SC Business & Economics
GA V40EH
UT WOS:000209461400001
ER
PT J
AU Humphrey, CP
O'Driscoll, MA
Deal, NE
Lindbo, DL
Thieme, SC
Zarate-Bermudez, MA
AF Humphrey, C. P., Jr.
O'Driscoll, M. A.
Deal, N. E.
Lindbo, D. L.
Thieme, S. C.
Zarate-Bermudez, M. A.
TI Onsite Wastewater System Nitrogen Contributions to Groundwater in
Coastal North Carolina
SO JOURNAL OF ENVIRONMENTAL HEALTH
LA English
DT Article
ID SAND AQUIFER; ESTUARY; NITRATE
AB The objective of the study described in this article was to evaluate the nitrogen contributions from two onsite wastewater systems (sites 1 and 2) to groundwater and adjacent surface waters in coastal Beaufort County, North Carolina. Groundwater levels and water quality parameters including total nitrogen, nitrogen species, temperature, and pH were monitored from October 2009 to May 2010. Nitrogen was also tested in groundwater from deeper irrigation or drinking water wells from the two sites and six additional neighboring residences. Mean total nitrogen concentrations in groundwater beneath onsite wastewater systems 1 and 2 were 34.3 +/- 16.7 mg/L and 12.2 +/- 2.9 mg/L, respectively, and significantly higher than background groundwater concentrations (<1 mg/L). Groundwater in the deeper wells appeared not to be influenced by the onsite systems. Groundwater nitrogen concentrations typically decreased with distance down-gradient from the systems, but were still elevated relative to background conditions more than 15 m from the systems and near the estuary. This was a pioneering effort to better understand the link of onsite systems, the fate of nitrogen in the environment, and public health.
C1 [Humphrey, C. P., Jr.] E Carolina Univ, Environm Hlth Sci Program, Greenville, NC 27858 USA.
[O'Driscoll, M. A.; Thieme, S. C.] E Carolina Univ, Dept Geol Sci, Greenville, NC 27858 USA.
[Deal, N. E.] North Carolina Dept Hlth & Human Serv, Raleigh, NC USA.
[Lindbo, D. L.] N Carolina State Univ, Dept Soil Sci & Cooperat Extens, Raleigh, NC 27695 USA.
[Zarate-Bermudez, M. A.] Ctr Dis Control & Prevent, Environm Hlth Serv Branch, Atlanta, GA 30341 USA.
RP Zarate-Bermudez, MA (reprint author), Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, 4770 Buford Highway,MS F-58, Atlanta, GA 30341 USA.
EM mcz4@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 22
TC 7
Z9 7
U1 0
U2 0
PU NATL ENVIRON HEALTH ASSOC
PI DENVER
PA 720 S COLORADO BLVD SUITE 970, SOUTH TOWER, DENVER, CO 80246 USA
SN 0022-0892
J9 J ENVIRON HEALTH
JI J. Environ. Health
PD DEC
PY 2013
VL 76
IS 5
BP 16
EP 22
PG 7
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA AO7NP
UT WOS:000341540200003
PM 24437045
ER
PT J
AU Coleman, EW
Delea, KC
AF Coleman, Erik W.
Delea, Kristin C.
TI The Use of Public Health Informatics to Improve Environmental Health
Practice
SO JOURNAL OF ENVIRONMENTAL HEALTH
LA English
DT Article
AB NEHA strives to provide up-to-date and relevant information on environmental health and to build partnerships in the profession. In pursuit of these goals, we feature a column from the Environmental Health Services Branch (EHSB) of the Centers for Disease Control and Prevention (CDC) in every issue of the Journal.
In this column, EHSB and guest authors from across CDC will highlight a variety of concerns, opportunities, challenges, and successes that we all share in enviromental public health. EHSB's objective is to strengthen the role of state, local, tribal, and national environmental health programs and professionals to anticipate, identify, and respond to adverse environmental exposures and the consequences of these exposures for human health.
The conclusions in this article are those of the author(s) and do not necessarily represent the views of CDC.
Erik W. Coleman is a public health informatics fellow at EHSB. Kristin C. Delea is an epidemiologist at EHSB.
C1 [Coleman, Erik W.] Ctr Dis Control & Prevent, Div Emergency & Environm Hlth Serv, Environm Hlth Serv Branch, Atlanta, GA 30341 USA.
RP Coleman, EW (reprint author), Ctr Dis Control & Prevent, Div Emergency & Environm Hlth Serv, Environm Hlth Serv Branch, 4770 Buford Highway NE,Mailstop F58, Atlanta, GA 30341 USA.
EM ecoleman@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 6
TC 1
Z9 1
U1 1
U2 8
PU NATL ENVIRON HEALTH ASSOC
PI DENVER
PA 720 S COLORADO BLVD SUITE 970, SOUTH TOWER, DENVER, CO 80246 USA
SN 0022-0892
J9 J ENVIRON HEALTH
JI J. Environ. Health
PD DEC
PY 2013
VL 76
IS 5
BP 44
EP 45
PG 2
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA AO7NP
UT WOS:000341540200007
PM 24437050
ER
PT J
AU Johnson, CH
Skinner, BL
Dietz, SM
Blaney, D
Engel, RM
Lathrop, GW
Hoffmaster, AR
Gee, JE
Elrod, MG
Powell, N
Walke, H
AF Johnson, Crystal H.
Skinner, Brianna L.
Dietz, Sharon M.
Blaney, David
Engel, Robyn M.
Lathrop, George W.
Hoffmaster, Alex R.
Gee, Jay E.
Elrod, Mindy G.
Powell, Nathaniel
Walke, Henry
TI Natural Infection of Burkholderia pseudomallei in an Imported Pigtail
Macaque (Macaca nemestrina) and Management of the Exposed Colony
SO COMPARATIVE MEDICINE
LA English
DT Article
ID PSEUDOMONAS-PSEUDOMALLEI; INDIRECT HEMAGGLUTINATION; NEUROLOGICAL
MELIOIDOSIS; MONKEY; OSTEOMYELITIS; DIAGNOSIS; GLANDERS; THAILAND;
PRIMATES; ANIMALS
AB Identification of the select agent Burkholderia pseudomallei in macaques imported into the United States is rare. A purpose-bred, 4.5-y-old pigtail macaque (Macaca nemestrina) imported from Southeast Asia was received from a commercial vendor at our facility in March 2012. After the initial acclimation period of 5 to 7 d, physical examination of the macaque revealed a subcutaneous abscess that surrounded the right stifle joint. The wound was treated and resolved over 3 mo. In August 2012, 2 mo after the stifle joint wound resolved, the macaque exhibited neurologic clinical signs. Postmortem microbiologic analysis revealed that the macaque was infected with B. pseudomallei. This case report describes the clinical evaluation of a B. pseudomallei-infected macaque, management and care of the potentially exposed colony of animals, and protocols established for the animal care staff that worked with the infected macaque and potentially exposed colony. This article also provides relevant information on addressing matters related to regulatory issues and risk management of potentially exposed animals and animal care staff.
C1 [Johnson, Crystal H.; Skinner, Brianna L.; Lathrop, George W.; Powell, Nathaniel] Ctr Dis Control & Prevent CDC, Natl Ctr Emerging & Zoonot Infect Dis, Div Sci Resources, Anim Resources Branch, Atlanta, GA USA.
[Dietz, Sharon M.; Engel, Robyn M.] Ctr Dis Control & Prevent CDC, Natl Ctr Emerging & Zoonot Infect Dis, Div Sci Resources, Anim Resources Branch,Lab Anim Med Residency Prog, Atlanta, GA USA.
[Blaney, David; Hoffmaster, Alex R.; Gee, Jay E.; Elrod, Mindy G.; Walke, Henry] Ctr Dis Control & Prevent CDC, Natl Ctr Emerging & Zoonot Infect Dis, Div High Consequence Pathogens & Pathol, Bacterial Special Pathogens Branch, Atlanta, GA USA.
RP Johnson, CH (reprint author), Icahn Sch Med Mt Sinai, Ctr Comparat Med & Surg, New York, NY 10029 USA.
EM crystal.johnson@mssm.edu
FU Laboratory Animal Medicine Residency Program at CDC
FX We thank the managers and technicians in the Animal Resources Branch at
CDC for their efforts in supporting the care of the animals housed at
our facility. Special acknowledgments are also extended to Dr Jana
Ritter and Dr Clifton Drew (Infectious Disease Pathology Branch, CDC)
for providing necropsy and histopathology information and David Lonsway
(Division of Healthcare Quality Promotion, CDC) for performing
antimicrobial susceptibility testing. We also thank Ms Joanne Jones
(Responsible Official, CDC); the Division of HIV-AIDS Prevention,
Laboratory Branch (CDC); and the numerous people who assisted in the
review of this article. Clinical care of the animals discussed in this
case report was supported in part by the Laboratory Animal Medicine
Residency Program at CDC.
NR 43
TC 4
Z9 4
U1 0
U2 2
PU AMER ASSOC LABORATORY ANIMAL SCIENCE
PI MEMPHIS
PA 9190 CRESTWYN HILLS DR, MEMPHIS, TN 38125 USA
SN 1532-0820
J9 COMPARATIVE MED
JI Comparative Med.
PD DEC
PY 2013
VL 63
IS 6
BP 528
EP 535
PG 8
WC Veterinary Sciences; Zoology
SC Veterinary Sciences; Zoology
GA AN7VW
UT WOS:000340810100010
PM 24326230
ER
PT J
AU Kolwaite, AR
Hlady, WG
Simon, MC
Cadwell, BL
Daley, WR
Fleischauer, AT
May, Z
Thoroughman, D
AF Kolwaite, Amy R.
Hlady, W. Gary
Simon, Matthew C.
Cadwell, Betsy L.
Daley, W. Randolph
Fleischauer, Aaron T.
May, Zora
Thoroughman, Doug
TI Assessing Functional Needs Sheltering in Pike County, Kentucky: Using a
Community Assessment for Public Health Emergency Response
SO DISASTER MEDICINE AND PUBLIC HEALTH PREPAREDNESS
LA English
DT Article
DE needs assessment; disaster planning; emergency preparedness
ID SAMPLING METHOD
AB Objective: During 2009-2011, Pike County, Kentucky, experienced a series of severe weather events that resulted in property damage, insufficient potable water, and need for temporary shelters. A Community Assessment for Public Health Emergency Response (CASPER) survey was implemented for future planning. CASPER assesses household health status, preparedness level, and anticipated demand for shelters.
Methods: We used a 2-stage cluster sampling design to randomly select 210 representative households for in-person interviews. We estimated the proportion of households with children aged 2 years or younger; adults aged 65 years or older; and residents with chronic health conditions, visual impairments, physical limitations, and supplemental oxygen requirements.
Results: Of all households surveyed, 8% included children aged 2 years or younger, and 27% included adults aged 65 years or older. The most common chronic health conditions were heart disease (51%), diabetes (28%), lung disease (23%), and asthma (21%). Visual impairments were reported in 29% of households, physical limitations in 24%, and supplemental oxygen use in 12%.
Conclusions: Pike County residents should be encouraged to maintain an adequate supply of medications and copies of their prescriptions. Emergency response plans should include transportation for persons with physical limitations; and shelter plans should include sufficient medically trained staff and adequate supplies of infant formula, pharmaceuticals, and supplemental oxygen. (Disaster Med Public Health Preparedness. 2013; 7: 597-602)
C1 [Kolwaite, Amy R.; Daley, W. Randolph] Epidem Intelligence Serv, Atlanta, GA USA.
[Cadwell, Betsy L.; Fleischauer, Aaron T.; Thoroughman, Doug] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Hlady, W. Gary] US Hlth Resources & Serv Adm, Bur Clinician Recruitment & Serv, San Francisco, CA USA.
[Simon, Matthew C.] Univ N Carolina, Ctr Publ Hlth Preparedness, North Carolina Inst Publ Hlth, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA.
[Kolwaite, Amy R.; Thoroughman, Doug] Kentucky Dept Publ Hlth, Frankfort, KY 40621 USA.
[May, Zora] Pike Cty Hlth Dept, Pikeville, KY USA.
[Fleischauer, Aaron T.] North Carolina Div Publ Hlth, Raleigh, NC USA.
RP Kolwaite, AR (reprint author), Kentucky Dept Publ Hlth, 275 E Main St HS 2GW-C, Frankfort, KY 40621 USA.
EM izj9@cdc.gov
NR 20
TC 1
Z9 1
U1 3
U2 7
PU CAMBRIDGE UNIV PRESS
PI NEW YORK
PA 32 AVENUE OF THE AMERICAS, NEW YORK, NY 10013-2473 USA
SN 1935-7893
EI 1938-744X
J9 DISASTER MED PUBLIC
JI Dis. Med. Public Health Prep.
PD DEC
PY 2013
VL 7
IS 6
BP 597
EP 602
DI 10.1017/dmp.2013.110
PG 6
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AL3XD
UT WOS:000339064000011
PM 24444133
ER
PT J
AU Blanck, HM
Collins, J
AF Blanck, Heidi M.
Collins, Janet
TI CDC's Winnable Battles: Improved Nutrition, Physical Activity, and
Decreased Obesity
SO CHILDHOOD OBESITY
LA English
DT Editorial Material
ID UNITED-STATES; CHILDREN; TRENDS
C1 [Blanck, Heidi M.; Collins, Janet] Ctr Dis Control & Prevent, Div Nutr Phys Act & Obes, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30341 USA.
RP Blanck, HM (reprint author), Ctr Dis Control & Prevent, Obes Prevent & Control Branch, Div Nutr Phys Act & Obes, Natl Ctr Chron Dis Prevent & Hlth Promot, 4770 Buford Highway,MS F-77, Atlanta, GA 30341 USA.
EM hcb3@cdc.gov
NR 18
TC 2
Z9 2
U1 0
U2 1
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 2153-2168
EI 2153-2176
J9 CHILD OBES
JI Child Obes.
PD DEC
PY 2013
VL 9
IS 6
BP 469
EP 471
DI 10.1089/chi.2013.9506
PG 3
WC Pediatrics
SC Pediatrics
GA AI5GA
UT WOS:000336892200001
PM 24236850
ER
PT J
AU Raffo, V
Bliss, T
Shotten, M
Sleet, D
Blanchard, C
AF Raffo, Veronica
Bliss, Tony
Shotten, Marc
Sleet, David
Blanchard, Claire
TI Case study: The Argentina Road Safety Project: lessons learned for the
decade of action for road safety, 2011-2020
SO GLOBAL HEALTH PROMOTION
LA English
DT Article
DE Argentina; guidelines; injury; management; road safety; World Bank
projects
AB This case study of the Argentina Road Safety Project demonstrates how the application of World Bank road safety project guidelines focused on institution building can accelerate knowledge transfer, scale up investment and improve the focus on results. The case study highlights road safety as a development priority and outlines World Bank initiatives addressing the implementation of the World Report on Road Traffic Injury's recommendations and the subsequent launch of the Decade of Action for Road Safety, from 2011-2020. The case study emphasizes the vital role played by the lead agency in ensuring sustainable road safety improvements and promoting the shift to a Safe System' approach, which necessitated the strengthening of all elements of the road safety management system. It summarizes road safety performance and institutional initiatives in Argentina leading up to the preparation and implementation of the project. We describe the project's development objectives, financing arrangements, specific components and investment staging. Finally, we discuss its innovative features and lessons learned, and present a set of supplementary guidelines, both to assist multilateral development banks and their clients with future road safety initiatives, and to encourage better linkages between the health and transportation sectors supporting them.
C1 [Raffo, Veronica; Shotten, Marc] World Bank, Washington, DC 20433 USA.
[Bliss, Tony] Monash Univ, Monash Injury Res Inst, Clayton, Vic 3800, Australia.
[Sleet, David] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Blanchard, Claire] Int Union Hlth Promot & Educ, St Denis, France.
RP Raffo, V (reprint author), World Bank, 1818 H St NW, Washington, DC 20433 USA.
EM vraffo@worldbank.org
NR 24
TC 3
Z9 3
U1 1
U2 4
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1757-9759
EI 1757-9767
J9 GLOB HEALTH PROMOT
JI Glob. Health Promot.
PD DEC
PY 2013
VL 20
SU 4
BP 20
EP 36
DI 10.1177/1757975913502690
PG 17
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AE7KO
UT WOS:000334176900003
PM 24722740
ER
PT J
AU Roehler, DR
Naumann, RB
Mutatina, B
Nakitto, M
Mwanje, B
Brondum, L
Blanchard, C
Baldwin, GT
Dellinger, AM
AF Roehler, Douglas R.
Naumann, Rebecca B.
Mutatina, Boniface
Nakitto, Mable
Mwanje, Barbara
Brondum, Lotte
Blanchard, Claire
Baldwin, Grant T.
Dellinger, Ann M.
TI Using baseline and formative evaluation data to inform the Uganda Helmet
Vaccine Initiative
SO GLOBAL HEALTH PROMOTION
LA English
DT Article
DE health behavior; health promotion; injury prevention; motorcycle
ID SAFETY; FATALITIES; VIETNAM
AB Motorcycles are an important form of transportation in Uganda, and are involved in more road traffic injuries than any other vehicle. The majority of motorcycles in Uganda are used as motorcycle taxis, better known locally as boda bodas. Research shows that a motorcycle helmet is effective at reducing a rider's risk of death and head injury. As part of the Uganda Helmet Vaccine Initiative (UHVI), researchers collected baseline and formative evaluation data on boda boda operators' helmet attitudes, beliefs, and behaviors to inform UHVI activities. Researchers collected data on motorcycle helmet-related attitudes and beliefs through focus group discussions and structured roadside interviews, and researchers conducted roadside observations to collect data on helmet-wearing behaviors. Of the 12,189 motorcycle operators and passengers observed during roadside observations, 30.8% of drivers and <1% of passengers were wearing helmets. The most commonly reported helmet-wearing barriers from the focus group discussions and structured roadside interviews were: (1) Helmet is uncomfortable', (2) Helmet is too hot', (3) Helmet is too expensive', and (4) Helmet is of low quality'. Researchers incorporated findings from the formative research into the UHVI campaign to increase motorcycle helmet use. Radio messages addressing helmet comfort and cost were widely aired throughout Kampala, Uganda. In addition, campaign staff held nine boda boda operator workshops, covering approximately 900 operators, in which the facilitator addressed barriers and facilitators to helmet use. Each workshop participant received a high-quality tropical motorcycle helmet. UHVI will continue to use a data-driven approach to future campaign activities.
C1 [Roehler, Douglas R.; Naumann, Rebecca B.; Baldwin, Grant T.; Dellinger, Ann M.] Ctr Dis Control & Prevent, Div Unintent Injury Prevent, Atlanta, GA USA.
[Roehler, Douglas R.] McNeal Profess Serv, Kennesaw, GA USA.
[Mutatina, Boniface; Nakitto, Mable] Injury Control Ctr Uganda, Kampala, Uganda.
[Mwanje, Barbara] Global Helmet Vaccine Initiat, Kampala, Uganda.
[Brondum, Lotte] Asia Injury Prevent Fdn, Hanoi, Vietnam.
[Blanchard, Claire] Int Union Hlth Promot & Educ, St Denis, France.
[Roehler, Douglas R.] Univ Michigan, Sch Publ Hlth, Ann Arbor, MI 48109 USA.
[Naumann, Rebecca B.] Univ N Carolina, Gillings Sch Publ Hlth, Chapel Hill, NC USA.
RP Roehler, DR (reprint author), Univ Michigan, Sch Publ Hlth, Ann Arbor, MI 48109 USA.
EM droehler@umich.edu
NR 27
TC 3
Z9 3
U1 1
U2 3
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1757-9759
EI 1757-9767
J9 GLOB HEALTH PROMOT
JI Glob. Health Promot.
PD DEC
PY 2013
VL 20
SU 4
BP 37
EP 44
DI 10.1177/1757975913509657
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AE7KO
UT WOS:000334176900004
PM 24722741
ER
PT J
AU Barboza, CF
Monteiro, SMDR
Barradas, SC
Sarmiento, OL
Rios, P
Ramirez, A
Mahecha, MP
Pratt, M
AF Finck Barboza, Carolyn
Monteiro, Sarojini M. D. R.
Barradas, Susana C.
Sarmiento, Olga L.
Rios, Paola
Ramirez, Andrea
Mahecha, Maria P.
Pratt, Michael
TI Physical activity, nutrition and behavior change in Latin America: a
systematic review
SO GLOBAL HEALTH PROMOTION
LA English
DT Article
DE health behavior; health promotion; physical activity; nutrition
ID PROTECTION MOTIVATION THEORY; EVIDENCE-BASED INTERVENTIONS;
TRANSTHEORETICAL MODEL; HEALTH-PROMOTION; SELF-EFFICACY; NONCOMMUNICABLE
DISEASES; PLANNED BEHAVIOR; PRIMARY-CARE; LIFE-STYLE; LOW-INCOME
AB Physical activity (PA) and nutrition are key health behaviors underlying the design and implementation of prevention strategies for non-communicable diseases (NCDs) in Latin America. Nevertheless, research still reports low prevalence of PA and fruit and vegetable consumption throughout the region. This paper aims at reviewing the ways in which models of behavior change theory have been applied in study development and implementation regarding nutrition and PA in Latin America. In August 2011 we conducted a systematic literature review of the behavior change studies that targeted such NCDs risk factors published until then. Out of 4279 surveyed abstracts, only 29 corresponded to articles that met our inclusion criteria. Twenty-six articles reported the application of behavior change theory, with the trans-theoretical model (n = 12) being the most frequently used. Other theories and models included the socio-ecological model (n = 4), cognitive theory (n = 3), social cognitive theory (n = 2) and theories related to health education and counseling (n = 5). Based on this review, we recommend that the application of behavior change theory be explicitly reported in Latin American peer-reviewed articles, and that outcome evaluations include behavior change constructs so as to better assess their contribution to the effectiveness of nutrition and PA interventions in the region. Furthermore, we state the need for a better understanding of the behavior change mechanisms that may be specific to the Latin American context.
C1 [Finck Barboza, Carolyn; Barradas, Susana C.] Univ Los Andes, Dept Psychol, Bogota, Colombia.
[Monteiro, Sarojini M. D. R.] Curtin Univ, Sch Publ Hlth, Perth, WA 6845, Australia.
[Sarmiento, Olga L.; Rios, Paola; Ramirez, Andrea; Mahecha, Maria P.; Pratt, Michael] Univ Los Andes, Sch Med, Bogota, Colombia.
[Pratt, Michael] Ctr Dis Control & Prevent CDC, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA.
RP Barboza, CF (reprint author), Univ Los Andes, Dept Psychol, Cra 1 18A-12, Bogota, Colombia.
EM cfinck@uniandes.edu.co
OI Sarmiento, Olga/0000-0002-9190-3568
NR 91
TC 6
Z9 6
U1 8
U2 19
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1757-9759
EI 1757-9767
J9 GLOB HEALTH PROMOT
JI Glob. Health Promot.
PD DEC
PY 2013
VL 20
SU 4
BP 65
EP 81
DI 10.1177/1757975913502240
PG 17
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AE7KO
UT WOS:000334176900007
ER
PT J
AU McQueen, D
Pratt, M
Blanchard, C
AF McQueen, David
Pratt, Michael
Blanchard, Claire
TI Commentary on a meeting entitled 'Building global capacity for
non-communicable diseases (NCD) prevention: Defining direction and
roles'
SO GLOBAL HEALTH PROMOTION
LA English
DT Editorial Material
DE chronic disease; effectiveness; non-communicable disease; capacity
building
AB This Commentary summarizes the key points that arose during a three-day meeting held in Atlanta in July 2012 on Building Global Capacity for NCD Prevention. A wide spectrum of participants representing many sectors of global health, including ministries of health from several low and middle-income countries (LMICs), governmental institutions, non-governmental organizations, national disease associations, academia, and global and regional institutions participated. Presentations and group discussions led to agreement on a number of actions that should be taken to increase capacity for coping with NCDs in LMICs. Key areas of discussion were on the role of research, workforce development, resources, and governance. While there was considerable agreement on what should be done, the workshop participants had difficulty in prioritizing these activities. This led to an agreement by the gathered participants that a follow-up Delphi study be conducted to help with prioritization.
C1 [McQueen, David] CDC, Atlanta, GA 30333 USA.
[Pratt, Michael] Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA.
[Blanchard, Claire] Int Union Hlth Promot & Educ, St Denis, France.
RP McQueen, D (reprint author), 2418 Midvale Ct, Tucker, GA 30084 USA.
EM davidmcqueen07@gmail.com
NR 5
TC 3
Z9 3
U1 0
U2 1
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1757-9759
EI 1757-9767
J9 GLOB HEALTH PROMOT
JI Glob. Health Promot.
PD DEC
PY 2013
VL 20
SU 4
BP 93
EP 96
DI 10.1177/1757975913509656
PG 4
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AE7KO
UT WOS:000334176900010
PM 24722747
ER
PT J
AU Kirkcaldy, RD
Kidd, S
Weinstock, HS
Papp, JR
Bolan, GA
AF Kirkcaldy, Robert D.
Kidd, Sarah
Weinstock, Hillard S.
Papp, John R.
Bolan, Gail A.
TI Trends in antimicrobial resistance in Neisseria gonorrhoeae in the USA:
the Gonococcal Isolate Surveillance Project (GISP), January 2006-June
2012
SO SEXUALLY TRANSMITTED INFECTIONS
LA English
DT Article
DE Antimicrobial Resistance; Neisseria Gonorrhoea; Surveillance
ID SEXUALLY-TRANSMITTED-DISEASES; PUBLIC-HEALTH LABORATORIES;
TREATMENT-GUIDELINES; RISK-FACTORS; NO LONGER; INFECTIONS;
SUSCEPTIBILITY; CEPHALOSPORIN; UPDATE
AB Background
Neisseria gonorrhoeae has progressively developed resistance to sulfonamides, penicillin, tetracycline and fluoroquinolones, and gonococcal susceptibility to cephalosporins has been declining worldwide.
Methods
We described trends in gonococcal antimicrobial susceptibility in the USA from January 2006 through June 2012. Susceptibility data for cefixime, ceftriaxone, azithromycin, penicillin, tetracycline and ciprofloxacin were obtained from the Gonococcal Isolate Surveillance Project (GISP), a sentinel surveillance system that monitors antimicrobial susceptibility in urethral gonococcal isolates collected from symptomatic men at 25-30 sexually transmitted disease clinics throughout the USA.
Results
The percentage of isolates with elevated cefixime minimum inhibitory concentrations (MICs) (>= 0.25 mu g/mL) increased from 0.1% in 2006 to 1.4% in 2010-2011 and was 1.1% in the first 6 months of 2012. The percentage with elevated ceftriaxone MICs (>= 0.125 mu g/mL) increased from 0.1% in 2006 to 0.3%-0.4% during 2009 through the first 6 months of 2012. There were no temporal trends in the prevalence of elevated azithromycin MICs (>= 2 mu g/mL) (0.2%-0.5%). The prevalence of resistance remained high for penicillin (11.2%-13.2%), tetracycline (16.7%-22.8%) and ciprofloxacin (9.6%-14.8%).
Conclusions
The proportion of gonococcal isolates with elevated cephalosporin MICs increased from 2006 to 2010, but plateaued during 2011 and the first 6 months of 2012. Resistance to previously recommended antimicrobials has persisted. As the number of antimicrobials available for gonorrhoea treatment dwindles, surveillance systems such as GISP will be critical to detect emerging resistance trends and guide treatment decisions.
C1 [Kirkcaldy, Robert D.; Kidd, Sarah; Weinstock, Hillard S.; Papp, John R.; Bolan, Gail A.] Ctr Dis Control & Prevent, Div STD Prevent, Atlanta, GA 30333 USA.
RP Kirkcaldy, RD (reprint author), Ctr Dis Control & Prevent, Div STD Prevent, 1600 Clifton Rd, Atlanta, GA 30333 USA.
EM rkirkcaldy@cdc.gov
FU Centers for Disease Control and Prevention
FX Centers for Disease Control and Prevention.
NR 33
TC 27
Z9 28
U1 0
U2 5
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 1368-4973
EI 1472-3263
J9 SEX TRANSM INFECT
JI Sex. Transm. Infect.
PD DEC
PY 2013
VL 89
IS 4
SU 4
BP 5
EP 10
DI 10.1136/sextrans-2013-051162
PG 6
WC Infectious Diseases
SC Infectious Diseases
GA AE3VS
UT WOS:000333907100003
PM 24243881
ER
PT J
AU Islam, A
Mikolon, A
Mikoleit, M
Ahmed, D
Khan, SU
Sharker, MAY
Hossain, MJ
Islam, A
Epstein, JH
Zeidner, N
Luby, SP
AF Islam, Ausraful
Mikolon, Andrea
Mikoleit, Matthew
Ahmed, Dilruba
Khan, Salah Udddin
Sharker, M. A. Yushuf
Hossain, M. Jahangir
Islam, Ariful
Epstein, Jonathan H.
Zeidner, Nord
Luby, Stephen P.
TI Isolation of Salmonella Virchow from a Fruit Bat (Pteropus giganteus)
SO ECOHEALTH
LA English
DT Article
DE fruit bats; Pteropus giganteus; Salmonella Typhi; Salmonella Virchow;
Bangladesh
ID TYPHOID-FEVER; BANGLADESH; DHAKA
AB Detection of zoonotic pathogens carried by bats is important both for understanding disease ecology and for developing preventive measures. Pteropus fruit bats have been identified as potential carriers of Salmonella enterica serotype Typhi. A cross-sectional study was conducted to determine the prevalence of Salmonella Typhi and other Salmonella serotypes in Pteropus giganteus fruit bats in Bangladesh. Rectal swabs were collected from 302 bats and cultured for Salmonella species. The bats were trapped in three districts (Faridpur, Rajbari, and Cox's Bazar). Salmonella Typhi was not found but one juvenile female bat from Faridpur district was positive for Salmonella Virchow. Close associations between frugivorous bats, humans, and livestock in rural Bangladesh make it likely that the bat was infected by consuming contaminated water.
C1 [Islam, Ausraful; Mikolon, Andrea; Ahmed, Dilruba; Khan, Salah Udddin; Sharker, M. A. Yushuf; Hossain, M. Jahangir; Zeidner, Nord; Luby, Stephen P.] ICDDR B, Dhaka 1212, Bangladesh.
[Mikoleit, Matthew] Ctr Dis Control & Prevent CDC, Enter Dis Lab Branch, Atlanta, GA USA.
[Islam, Ariful; Epstein, Jonathan H.] EcoHealth Alliance, New York, NY 10001 USA.
[Epstein, Jonathan H.] Univ Kingston, Sch Life Sci, Kingston Upon Thames KT1 2EE, Surrey, England.
RP Islam, A (reprint author), ICDDR B, 68 Shaheed Tajuddin Ahmed Sharani, Dhaka 1212, Bangladesh.
EM islam_ausraf@icddrb.org
OI Luby, Stephen/0000-0001-5385-899X
FU National Institute of Health (NIH) through EchoHealth Alliance
[07-015-0712-52200]
FX This research study was funded by the National Institute of Health (NIH)
through EchoHealth Alliance, Grant Number 07-015-0712-52200. ICDDR,B
acknowledges with gratitude the commitment of NIH to its research
efforts. ICDDR,B is grateful to CDC for their laboratory support for the
study.
NR 22
TC 1
Z9 1
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1612-9202
EI 1612-9210
J9 ECOHEALTH
JI EcoHealth
PD DEC
PY 2013
VL 10
IS 4
BP 348
EP 351
DI 10.1007/s10393-013-0866-y
PG 4
WC Biodiversity Conservation; Ecology; Environmental Sciences
SC Biodiversity & Conservation; Environmental Sciences & Ecology
GA AC2VT
UT WOS:000332375100005
PM 24136382
ER
PT J
AU Parra, DC
Hoehner, CM
Hallal, PC
Reis, RS
Simoes, EJ
Malta, DC
Pratt, M
Brownson, RC
AF Parra, Diana C.
Hoehner, Christine M.
Hallal, Pedro C.
Reis, Rodrigo S.
Simoes, Eduardo J.
Malta, Deborah C.
Pratt, Michael
Brownson, Ross C.
TI Scaling up of physical activity interventions in Brazil: how
partnerships and research evidence contributed to policy action
SO GLOBAL HEALTH PROMOTION
LA English
DT Article
DE physical activity; policy; practice; program planning; management;
collaboration; partnership; communicable disease
ID LATIN-AMERICA; CHALLENGES; PROMOTION; PROGRAM; WORLD
AB The global health burden due to physical inactivity is enormous and growing. There is a need to consider new ways of generating evidence and to identify the role of government in promoting physical activity at the population level. In this paper, we summarize key findings from a large-scale cross-national collaboration to understand physical activity promotion in Brazil. We describe the main aspects of the partnership of Project GUIA (Guide for Useful Interventions for Activity in Brazil and Latin America) that sustained the collaborative effort for eight years and describe how the evidence gathered from the collaboration triggered political action in Brazil to scale up a physical activity intervention at the national level. Project GUIA is a cross-national multidisciplinary research partnership designed to understand and evaluate current efforts for physical activity promotion at the community level in Latin America. This example of scaling up is unprecedented for promoting health in the region and is an example that must be followed and evaluated.
C1 [Parra, Diana C.] Washington Univ, Prevent Res Ctr, St Louis, MO 63130 USA.
[Hoehner, Christine M.; Brownson, Ross C.] Washington Univ, Div Publ Hlth Sci, St Louis, MO USA.
[Hoehner, Christine M.; Brownson, Ross C.] Alvin J Siteman Canc Ctr, Sch Med St Louis, St Louis, MO USA.
[Hallal, Pedro C.] Univ Fed Pelotas, Postgrad Program Epidemiol, Pelotas, Brazil.
[Reis, Rodrigo S.] Pontificia Univ Catolica Parana, Dept Phys Educ, Curitiba, Parana, Brazil.
[Reis, Rodrigo S.] Univ Fed Parana, Dept Phys Educ, BR-80060000 Curitiba, Parana, Brazil.
[Simoes, Eduardo J.] Univ Missouri, Sch Med, Dept Hlth Management & Informat, Columbia, MO USA.
[Malta, Deborah C.] Minist Hlth Brazil, Div Situat Anal & Prevent Nontransmissible Dis, Brasilia, DF, Brazil.
[Pratt, Michael] Ctr Dis Control & Prevent, Off Global Hlth, Atlanta, GA USA.
RP Parra, DC (reprint author), Washington Univ, Prevent Res Ctr, 8150 Whitburn Dr 2 W, St Louis, MO 63130 USA.
EM dianacpp79@yahoo.com
RI Hallal, Pedro/A-3249-2011; Parra, Diana/B-7761-2015; Reis,
Rodrigo/F-7447-2012; Malta, Deborah/H-7880-2012
OI Hallal, Pedro/0000-0003-1470-6461; Parra, Diana/0000-0002-9797-6231;
Reis, Rodrigo/0000-0002-9872-9865; Malta, Deborah/0000-0002-8214-5734
FU NCCDPHP CDC HHS [U48 DP001903]; NIDDK NIH HHS [P30 DK092950]; Wellcome
Trust [095582]
NR 43
TC 10
Z9 11
U1 1
U2 4
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1757-9759
EI 1757-9767
J9 GLOB HEALTH PROMOT
JI Glob. Health Promot.
PD DEC
PY 2013
VL 20
IS 4
BP 5
EP 12
DI 10.1177/1757975913502368
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AA6GV
UT WOS:000331197700002
PM 24323944
ER
PT J
AU Bachani, AM
Branching, C
Ear, C
Roehler, DR
Parker, EM
Tum, S
Ballesteros, MF
Hyder, AA
AF Bachani, Abdulgafoor M.
Branching, Casey
Ear, Chariya
Roehler, Douglas R.
Parker, Erin M.
Tum, Sotheary
Ballesteros, Michael F.
Hyder, Adnan A.
TI Trends in prevalence, knowledge, attitudes, and practices of helmet use
in Cambodia: results from a two year study
SO INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
LA English
DT Article
DE Motorcycle; Head injuries; Cambodia; Road safety; Asia
ID HEAD-INJURIES; MOTORCYCLISTS; COUNTRIES; RIDERS; MODEL; LAWS
AB Introduction: Road traffic injuries (RTIs) are a major cause of both morbidity and mortality globally. Relative to countries with similar economic patterns both within and outside of South-East Asia, Cambodia's road traffic fatality rate is high, with motorcyclists accounting for more than half of all fatalities as a result of head injuries. Despite the initiation of national motorcycle helmet legislation for Cambodian drivers in 2009, helmet use among both drivers and passengers remains low.
Methods: This study adopted a two-pronged approach to assess the current status of and knowledge, attitudes, and practices (KAPs) towards helmet use among drivers and passengers in five provinces in Cambodia. The objective was to better understand helmet use over a two year period since the introduction of the 2009 legislation. Researchers conducted both (1) direct observation of daytime and nighttime helmet use (January 2011-January 2013) and (2) roadside KAP interviews with motorcyclists (November 2010-November 2012).
Results: The observed helmet rate across all study sites was 33% during nighttime and 48% during daytime, with proportions up to ten times higher among drivers compared with passengers. Self-reported helmet use was higher than observed use. Within the past 30 days, 60% of respondents reported that they "always" wore a helmet when they were drivers while only 24% reported they "always" wore a helmet as a passenger. Reported barriers for use among drivers included: "driving route", "forgetfulness", and "inconvenience/discomfort."
Conclusion: Despite awareness of the protective value of helmets, motorcycle helmet use rates remain low in Cambodia. Many misconceptions remain in Cambodia regarding helmet use, including that they are unnecessary for short distance or at low speeds. These serve as an important barrier to helmet use, which, if dispelled and coupled with visible and regular enforcement, may significantly reduce the number of motorcycle-related injuries and fatalities. (C) 2013 Elsevier Ltd. All rights reserved.
C1 [Bachani, Abdulgafoor M.; Branching, Casey; Hyder, Adnan A.] Johns Hopkins Bloomberg Sch Publ Hlth, Johns Hopkins Int Injury Res Unit, Baltimore, MD USA.
[Ear, Chariya; Tum, Sotheary] Handicap Int Belgium, Phnom Penh, Cambodia.
[Roehler, Douglas R.; Parker, Erin M.] Ctr Dis Control & Prevent, Div Unintent Injury Prevent, Natl Ctr Injury Prevent & Control, Atlanta, GA USA.
[Ballesteros, Michael F.] Ctr Dis Control & Prevent, Div Global Hlth Protect, Ctr Global Hlth, Atlanta, GA USA.
RP Bachani, AM (reprint author), 615 N Wolfe St,Suite E-8132, Baltimore, MD 21205 USA.
EM abachani@jhsph.edu
FU Bloomberg Philanthropies
FX This work was conducted as part of the Global Road Safety Programmes,
funded by Bloomberg Philanthropies. Additional support for some of the
data collection provided by the Centers for Disease Control and
Prevention and the Asia Injury Prevention Foundation.
NR 25
TC 6
Z9 7
U1 1
U2 4
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0020-1383
EI 1879-0267
J9 INJURY
JI Injury-Int. J. Care Inj.
PD DEC
PY 2013
VL 44
SU 4
BP S31
EP S37
PG 7
WC Critical Care Medicine; Emergency Medicine; Orthopedics; Surgery
SC General & Internal Medicine; Emergency Medicine; Orthopedics; Surgery
GA AA9II
UT WOS:000331406600007
PM 24377776
ER
PT J
AU Schilling, K
Person, B
Faith, SH
Otieno, R
Quick, R
AF Schilling, Katharine
Person, Bobbie
Faith, Sitnah H.
Otieno, Ronald
Quick, Robert
TI The Challenge of Promoting Interventions to Prevent Disease in
Impoverished Populations in Rural Western Kenya
SO AMERICAN JOURNAL OF PUBLIC HEALTH
LA English
DT Article
ID WATER; COMMUNITY; DIARRHEA; ENOUGH
AB Poverty is a critical social determinant of health. A particular approach toward mitigating inequitable access to health services in Kenya has been through a community-based distribution program implemented by the Safe Water and AIDS Project (SWAP) that has achieved modest uptake of public health interventions. To explore reasons for modest uptake, we asked program participants about child health problems, daily tasks, household expenditures, and services needed by their communities. Respondents identified child health problems consistent with health data and reported daily tasks, expenses, and needed services that were more related to basic needs of life other than health. These findings highlight the challenges of implementing potentially self-sustaining preventive interventions at scale in poor populations in the developing world.
C1 [Schilling, Katharine; Quick, Robert] US Ctr Dis Control & Prevent, Div Foodborne Waterborne & Environm Dis, Waterborne Dis Prevent Branch, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA USA.
[Person, Bobbie] US Ctr Dis Control & Prevent, Off Director, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA USA.
[Faith, Sitnah H.; Otieno, Ronald] Safe Water & AIDS Project, Kisumu, Kenya.
RP Schilling, K (reprint author), Ctr Dis Control & Prevent, Waterborne Dis Prevent Branch, 1600 Clifton Rd NE,MS C09, Atlanta, GA 30329 USA.
EM kschilling@cdc.gov
RI Mashamba-Thompson, Tivani /B-6087-2014
FU Centers for Disease Control and Prevention (CDC); United States Agency
for International Development
FX Financial support for this study was provided by the Centers for Disease
Control and Prevention (CDC) and the United States Agency for
International Development.
NR 20
TC 2
Z9 2
U1 0
U2 6
PU AMER PUBLIC HEALTH ASSOC INC
PI WASHINGTON
PA 800 I STREET, NW, WASHINGTON, DC 20001-3710 USA
SN 0090-0036
EI 1541-0048
J9 AM J PUBLIC HEALTH
JI Am. J. Public Health
PD DEC
PY 2013
VL 103
IS 12
BP 2131
EP 2135
DI 10.2105/AJPH.2013.301459
PG 5
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AA4CV
UT WOS:000331043200020
PM 24188638
ER
PT J
AU Sutton, MY
Lanier, YA
Willis, LA
Castellanos, T
Dominguez, K
Fitzpatrick, L
Miller, KS
AF Sutton, Madeline Y.
Lanier, Yzette A.
Willis, Leigh A.
Castellanos, Ted
Dominguez, Ken
Fitzpatrick, Lisa
Miller, Kim S.
TI Strengthening the Network of Mentored, Underrepresented Minority
Scientists and Leaders to Reduce HIV-Related Health Disparities
SO AMERICAN JOURNAL OF PUBLIC HEALTH
LA English
DT Article
ID PROGRAM; INVESTIGATORS; COMMUNITIES; PREVENTION; BARRIERS; BLACK; CARE;
HIV/AIDS; MODEL; GAPS
AB Objectives. We reviewed data for the Minority HIV/AIDS Research Initiative (MARI), which was established in 2003 to support underrepresented minority scientists performing HIV prevention research in highly affected communities.
Methods. MARI was established at the Centers for Disease Prevention and Control as a program of competitively awarded, mentored grants for early career researchers conducting HIV prevention research in highly affected racial/ethnic and sexual minority communities. We have described progress from 2003 to 2013.
Results. To date, MARI has mentored 27 scientist leaders using low-cost strategies to enhance the development of effective HIV prevention interventions. These scientists have (1) developed research programs in disproportionately affected communities of color, (2) produced first-authored peer-reviewed scientific and programmatic products (including articles and community-level interventions), and (3) obtained larger, subsequent funding awards for research and programmatic work related to HIV prevention and health disparities work.
Conclusions. The MARI program demonstrates how to effectively engage minority scientists to conduct HIV prevention research and reduce racial/ethnic investigator disparities and serves as a model for programs to reduce disparities in other public health areas in which communities of color are disproportionately affected.
C1 [Sutton, Madeline Y.; Lanier, Yzette A.; Willis, Leigh A.; Castellanos, Ted; Dominguez, Ken; Fitzpatrick, Lisa; Miller, Kim S.] Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA USA.
RP Sutton, MY (reprint author), DHAP NCHHSTP CDC, 1600 Clifton Rd NE,MS E-45, Atlanta, GA 30333 USA.
EM zxa3@cdc.gov
FU Centers for Disease Control and Prevention, Division of HIV/AIDS
Prevention [PS07-003, PS11-003]
FX The Centers for Disease Control and Prevention, Division of HIV/AIDS
Prevention funded the Minority HIV/AIDS Research Initiative (cooperative
agreements PS07-003 and PS11-003).
NR 41
TC 9
Z9 9
U1 0
U2 3
PU AMER PUBLIC HEALTH ASSOC INC
PI WASHINGTON
PA 800 I STREET, NW, WASHINGTON, DC 20001-3710 USA
SN 0090-0036
EI 1541-0048
J9 AM J PUBLIC HEALTH
JI Am. J. Public Health
PD DEC
PY 2013
VL 103
IS 12
BP 2207
EP 2214
DI 10.2105/AJPH.2013.301345
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AA4CV
UT WOS:000331043200034
PM 24134360
ER
PT J
AU Samoff, E
DiBiase, L
Fangman, MT
Fleischauer, AT
Waller, AE
MacDonald, PDM
AF Samoff, Erika
DiBiase, Lauren
Fangman, Mary T.
Fleischauer, Aaron T.
Waller, Anna E.
MacDonald, Pia D. M.
TI We Can Have It All: Improved Surveillance Outcomes and Decreased
Personnel Costs Associated With Electronic Reportable Disease
Surveillance, North Carolina, 2010
SO AMERICAN JOURNAL OF PUBLIC HEALTH
LA English
DT Article
ID STATE HEALTH DEPARTMENTS; UNITED-STATES; EPIDEMIOLOGY CAPACITY; LOCAL
HEALTH; SYSTEMS
AB Objectives. We assessed the timeliness, accuracy, and cost of a new electronic disease surveillance system at the local health department level. We describe practices associated with lower cost and better surveillance timeliness and accuracy.
Methods. Interviews conducted May through August 2010 with local health department (LHD) staff at a simple random sample of 30 of 100 North Carolina counties provided information on surveillance practices and costs; we used surveillance system data to calculate timeliness and accuracy. We identified LHDs with best timeliness and accuracy and used these categories to compare surveillance practices and costs.
Results. Local health departments in the top tertiles for surveillance timeliness and accuracy had a lower cost per case reported than LHDs with lower timeliness and accuracy ($71 and $124 per case reported, respectively; P = .03). Best surveillance practices fell into 2 domains: efficient use of the electronic surveillance system and use of surveillance data for local evaluation and program management.
Conclusions. Timely and accurate surveillance can be achieved in the setting of restricted funding experienced by many LHDs. Adopting best surveillance practices may improve both efficiency and public health outcomes.
C1 [Samoff, Erika; DiBiase, Lauren; Fangman, Mary T.; MacDonald, Pia D. M.] Univ N Carolina, Inst Publ Hlth, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA.
[Fleischauer, Aaron T.] Ctr Dis Control & Prevent, Raleigh, NC USA.
[Fleischauer, Aaron T.] North Carolina Div Publ Hlth, Raleigh, NC USA.
[Waller, Anna E.] Univ N Carolina, Dept Emergency Med, Carolina Ctr Hlth Informat, Chapel Hill, NC USA.
RP Samoff, E (reprint author), Durham Cty Dept Publ Hlth, 414 E Main St, Durham, NC 27701 USA.
EM esamoff@dconc.gov
FU Centers for Disease Control and Prevention (CDC) [1PO1 TP 000296]
FX This research was supported by the Centers for Disease Control and
Prevention (CDC; grant 1PO1 TP 000296).
NR 20
TC 0
Z9 0
U1 1
U2 4
PU AMER PUBLIC HEALTH ASSOC INC
PI WASHINGTON
PA 800 I STREET, NW, WASHINGTON, DC 20001-3710 USA
SN 0090-0036
EI 1541-0048
J9 AM J PUBLIC HEALTH
JI Am. J. Public Health
PD DEC
PY 2013
VL 103
IS 12
BP 2292
EP 2297
DI 10.2105/AJPH.2013.301353
PG 6
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA AA4CV
UT WOS:000331043200045
PM 24134385
ER
PT J
AU Dhara, VR
Schramm, PJ
Luber, G
AF Dhara, V. Ramana
Schramm, Paul J.
Luber, George
TI Climate change & infectious diseases in India: Implications for health
care providers
SO INDIAN JOURNAL OF MEDICAL RESEARCH
LA English
DT Review
DE Climate change; human health; India; vector-borne disease; water-borne
disease
ID FLOODS; BANGLADESH; IMPACTS; MALARIA; LEPTOSPIROSIS; ADAPTATION;
OUTBREAK
AB Climate change has the potential to influence the earth's biological systems, however, its effects on human health are not well defined. Developing nations with limited resources are expected to face a host of health effects due to climate change, including vector-borne and water-borne diseases such as malaria, cholera, and dengue. This article reviews common and prevalent infectious diseases in India, their links to climate change, and how health care providers might discuss preventive health care strategies with their patients.
C1 [Dhara, V. Ramana] Ctr Dis Control & Prevent, Environm Safety & Hlth Compliance Off, Atlanta, GA 30341 USA.
[Schramm, Paul J.; Luber, George] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Climate & Hlth Program, Atlanta, GA 30341 USA.
RP Schramm, PJ (reprint author), Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, 4770 Buford Hwy,Bldg 106, Atlanta, GA 30341 USA.
EM PSchramm@cdc.gov
NR 39
TC 5
Z9 7
U1 4
U2 15
PU INDIAN COUNCIL MEDICAL RES
PI NEW DELHI
PA PO BOX 4911 ANSARI NAGAR, NEW DELHI 110029, INDIA
SN 0971-5916
J9 INDIAN J MED RES
JI Indian J. Med. Res.
PD DEC
PY 2013
VL 138
BP 847
EP 852
PG 6
WC Immunology; Medicine, General & Internal; Medicine, Research &
Experimental
SC Immunology; General & Internal Medicine; Research & Experimental
Medicine
GA AA1TV
UT WOS:000330879500008
PM 24521625
ER
PT J
AU Purakayastha, DR
Gupta, V
Broor, S
Sullender, W
Fowler, K
Widdowson, MA
Lal, RB
Krishnan, A
AF Purakayastha, Debjani Ram
Gupta, Vivek
Broor, Shobha
Sullender, Wayne
Fowler, Karen
Widdowson, Marc-Alain
Lal, Renu B.
Krishnan, Anand
TI Clinical differences between influenza A (H1N1) pdm09 & influenza B
infections identified through active community surveillance in north
India
SO INDIAN JOURNAL OF MEDICAL RESEARCH
LA English
DT Article
DE Diagnosis; influenza A; influenza B; H1N1 subtype; respiratory tract
infections; signs and symptoms
ID SEASONAL INFLUENZA; DESIGN
AB Background & objectives: Most studies on the clinical presentation with influenza viruses have been conducted in outpatient or inpatient medical facilities with only a few studies in community settings. Clinical differences between influenza A (H1N1) pdm 09 and influenza B virus infections have importance for community-based public health surveillance. An active community surveillance at the time of emergence of pandemic influenza provided us with an opportunity to compare the clinical features among patients infected with influenza A (H1N1) pdm09 virus and those with influenza B virus co-circulating in an active community-based weekly surveillance in three villages in Faridabad, Haryana, north India.
Methods: Active surveillance for febrile acute respiratory infection (FARI) was carried out in a rural community (n=16,182) in the context of an inactivated trivalent influenza vaccine trial (among children <11 yr). Individuals with FARI were assessed clinically by nurses and respiratory samples collected and tested for influenza viruses by real time RT-PCR from November 2009 to August 2010. Clinical symptoms of patients with influenza A (H1N1) pdm 09 and influenza B infection were compared.
Results: Of the 4796 samples tested, 822 (17%) were positive for influenza virus. Of these, 443 (54%) were influenza A (H1N1) pdm09, 373 (45%) were influenza B and six were other subtypes/mixed infections. The mean age was lower for patients with influenza B (16.4 yr) than influenza A (H1N1) pdm09 infection (18.7 yr; P=0.04). Among children aged 5-18 yr, chills/rigours (OR 4.0; CI 2.2, 7.4), sore throat (OR 6.8; CI 2.3, 27.3) and headache (OR2.0; CI 1.3, 3.3) were more common in influenza A (H1N1) pdm09 infection than in influenza B cases. Chills/rigours (OR 2.4; CI 1.4, 4.0) and headache (OR 1.7; CI 1.0, 2.7) were associated with influenza A (H1N1) pdm09 infection in those >18 yr. No significant differences were seen in children <5 yr.
Conclusion: Our findings show that the differences in the clinical presentation of influenza A(H1N1) pdm09 and influenza B infections are not likely to be of clinical or public health significance.
C1 [Purakayastha, Debjani Ram; Broor, Shobha; Krishnan, Anand] All India Inst Med Sci, Ctr Community Med, Dept Microbiol, New Delhi 110029, India.
[Gupta, Vivek] InCLEN Trust Int, New Delhi, India.
[Sullender, Wayne; Fowler, Karen] Univ Alabama Birmingham, Dept Paediat, Birmingham, AL USA.
[Widdowson, Marc-Alain; Lal, Renu B.] US Ctr Dis Control & Prevent, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
RP Krishnan, A (reprint author), All India Inst Med Sci, Ctr Community Med, New Delhi 110029, India.
EM anand.drk@gmail.com
OI Krishnan, Anand/0000-0002-9173-7811
FU Centers for Disease Control and Prevention, Atlanta, USA [U01IP000177]
FX Authors thank the residents of the study villages, the field and
laboratory staff for their commitment, and the CDC Influenza Division
personnel for their constructive comments during the pre-submission
peer-review process. Anthony Mounts and Joshua Mott participated in
initial planning for this study. The study was supported by cooperative
agreements U01IP000177 from the Centers for Disease Control and
Prevention, Atlanta, USA.
NR 31
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U1 0
U2 4
PU INDIAN COUNCIL MEDICAL RES
PI NEW DELHI
PA PO BOX 4911 ANSARI NAGAR, NEW DELHI 110029, INDIA
SN 0971-5916
J9 INDIAN J MED RES
JI Indian J. Med. Res.
PD DEC
PY 2013
VL 138
BP 962
EP 968
PG 7
WC Immunology; Medicine, General & Internal; Medicine, Research &
Experimental
SC Immunology; General & Internal Medicine; Research & Experimental
Medicine
GA AA1TV
UT WOS:000330879500026
PM 24521643
ER
PT J
AU Khan, UH
Mir, MA
Ahmad, F
Mir, MH
Bali, NK
Lal, RB
Broor, SS
Koul, PA
AF Khan, Umar H.
Mir, Muneer A.
Ahmad, Feroze
Mir, M. Hussain
Bali, Nargis K.
Lal, Renu B.
Broor, Shobha S.
Koul, Parvaiz A.
TI An outbreak of influenza B in an isolated nomadic community in Jammu &
Kashmir, India
SO INDIAN JOURNAL OF MEDICAL RESEARCH
LA English
DT Article
DE Epidemiology; influenza B; nomads; outbreak
AB Background & objectives: Community outbreaks of disease amongst nomadic populations generally remain undocumented. Following a reported increase in acute respiratory tract infections (ARI) in May 2011 in a nomadic population of Sangerwini in Jammu & Kashmir, India, we examined the patients with ARI symptoms and their nasal swabs were tested for influenza virus.
Methods: Patients with ARI (n=526) were screened from May 14 to 23, 2011 and nasopharyngeal swabs collected from 84 with Influenza like illness (ILI) for bacterial cultures and influenza virus testing. Samples were tested for influenza A and influenza B by real time (RT)-PCR.
Results: Twelve (14.3%) of the 84 patients tested positive for influenza B, compared to only one (0.9%) of 108 patients with ILI in a parallel survey performed in Srinagar during the same period, suggesting a localized outbreak in the isolated nomadic community. All presented with respiratory symptoms of less than seven days. Familial clustering was seen in 40 per cent (25% of influenza B positives). Average daytime temperatures ranged from 15-16 degrees C compared to 22 degrees C in Srinagar. Four patients developed pneumonia whereas others ran a mild course with a total recovery with oseltamivir and symptomatic therapy.
Interpretation & conclusion: Our report of confirmed influenza B in this underprivileged nomadic population argues for routine surveillance with efforts to improve vaccination and infection control practices.
C1 [Khan, Umar H.; Ahmad, Feroze; Mir, M. Hussain; Koul, Parvaiz A.] Sherikashmir Inst Med Sci, Dept Internal & Pulm Med, Srinagar 190011, Jammu & Kashmir, India.
[Mir, Muneer A.; Bali, Nargis K.] Sherikashmir Inst Med Sci, Dept Clin Microbiol, Srinagar 190011, Jammu & Kashmir, India.
[Broor, Shobha S.] All India Inst Med Sci, Dept Virol, New Delhi, India.
[Lal, Renu B.] Ctr Dis Control & Prevent CDC, Influenza Div, Atlanta, GA USA.
RP Koul, PA (reprint author), Sherikashmir Inst Med Sci, Dept Internal & Pulm Med, Srinagar 190011, Jammu & Kashmir, India.
EM parvaizk@gmail.com
FU Centre for Disease Control and Prevention, Influenza Division, Atlanta,
GA, USA
FX The study was funded by the Centre for Disease Control and Prevention,
Influenza Division, Atlanta, GA, USA.
NR 17
TC 2
Z9 2
U1 0
U2 0
PU INDIAN COUNCIL MEDICAL RES
PI NEW DELHI
PA PO BOX 4911 ANSARI NAGAR, NEW DELHI 110029, INDIA
SN 0971-5916
J9 INDIAN J MED RES
JI Indian J. Med. Res.
PD DEC
PY 2013
VL 138
BP 1012
EP 1015
PG 4
WC Immunology; Medicine, General & Internal; Medicine, Research &
Experimental
SC Immunology; General & Internal Medicine; Research & Experimental
Medicine
GA AA1TV
UT WOS:000330879500032
PM 24521649
ER
PT J
AU Caillouet, KA
Robertson, CW
Wheeler, DC
Komar, N
Bulluck, LP
AF Caillouet, Kevin A.
Robertson, Charles W.
Wheeler, David C.
Komar, Nicholas
Bulluck, Lesley P.
TI Vector Contact Rates on Eastern Bluebird Nestlings Do Not Indicate West
Nile Virus Transmission in Henrico County, Virginia, USA
SO INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
LA English
DT Article
DE host-seeking rate; nestling; nest mosquito trap; arbovirus; West Nile
virus
ID EXPERIMENTAL-INFECTION; FEEDING-BEHAVIOR; BIRDS; AMPLIFICATION;
COLORADO; DOMESTICUS; ANTIBODIES; MOSQUITOS; GEORGIA; FLORIDA
AB Sensitive indicators of spatial and temporal variation in vector-host contact rates are critical to understanding the transmission and eventual prevention of arboviruses such as West Nile virus (WNV). Monitoring vector contact rates on particularly susceptible and perhaps more exposed avian nestlings may provide an advanced indication of local WNV amplification. To test this hypothesis we monitored WNV infection and vector contact rates among nestlings occupying nest boxes (primarily Eastern bluebirds; Sialia sialis, Turdidae) across Henrico County, Virginia, USA, from May to August 2012. Observed host-seeking rates were temporally variable and associated with absolute vector and host abundances. Despite substantial effort to monitor WNV among nestlings and mosquitoes, we did not detect the presence of WNV in these populations. Generally low vector-nestling host contact rates combined with the negative WNV infection data suggest that monitoring transmission parameters among nestling Eastern bluebirds in Henrico County, Virginia, USA may not be a sensitive indicator of WNV activity.
C1 [Caillouet, Kevin A.] St Tammany Parish Mosquito Abatement Dist, Slidell, LA 70460 USA.
[Caillouet, Kevin A.; Robertson, Charles W.; Bulluck, Lesley P.] Virginia Commonwealth Univ, Dept Biol, Richmond, VA 23284 USA.
[Wheeler, David C.] Virginia Commonwealth Univ, Dept Biostat, Richmond, VA 23219 USA.
[Komar, Nicholas] Ctr Dis Control & Prevent, Div Vector Borne Infect Dis, Ft Collins, CO 80521 USA.
RP Caillouet, KA (reprint author), St Tammany Parish Mosquito Abatement Dist, 62512 Airport Rd Bldg 23, Slidell, LA 70460 USA.
EM caillouet@stpmad.org; robertsoncw@vcu.edu; dcwheeler@vcu.edu;
nkomar@cdc.gov; lpbulluck@vcu.edu
FU AD Williams' Fund of the Virginia Commonwealth University (VCU); VCU
CTSA from the National Center for Research Resources [UL1RR031990]
FX The authors thank Randy Buchanan, Lane Carr, Jennifer Welch and the
seasonal staff at the Henrico County Standing Water Initiative for the
use of their mosquito surveillance network data. Thanks to Nick Panella
for his assistance with preparing specimens for testing. Thanks also to
James Cox for helping with nest box construction. Eric Krause assisted
with nest box monitoring. We are grateful to the public and private land
owners of Henrico County who granted us site access. Bird banding was
conducted under USGS Banding Permit #22751 and Virginia Department of
Game and Inland Fisheries permit #041077. Bird handling was approved by
the Virginia Commonwealth University Animal Care and Use Committee
(IACUC Protocol #AM10230). Project support funds were provided by the AD
Williams' Fund of the Virginia Commonwealth University (VCU) and the VCU
CTSA (UL1RR031990 from the National Center for Research Resources).
NR 35
TC 1
Z9 1
U1 0
U2 6
PU MDPI AG
PI BASEL
PA POSTFACH, CH-4005 BASEL, SWITZERLAND
SN 1660-4601
J9 INT J ENV RES PUB HE
JI Int. J. Environ. Res. Public Health
PD DEC
PY 2013
VL 10
IS 12
BP 6366
EP 6379
DI 10.3390/ijerph10126366
PG 14
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA 296XV
UT WOS:000330219600010
PM 24287858
ER
PT J
AU Holmes, B
Steigerwalt, AG
Nicholson, AC
AF Holmes, B.
Steigerwalt, A. G.
Nicholson, A. C.
TI DNA-DNA hybridization study of strains of Chryseobacterium,
Elizabethkingia and Empedobacter and of other usually indole-producing
non-fermenters of CDC groups Ilc, Ile, Ilh and Ili, mostly from human
clinical sources, and proposals of Chryseobacterium bernardetii sp nov.,
Chryseobacterium carnis sp nov., Chryseobacterium lactis sp nov.,
Chryseobacterium nakagawai sp nov and Chryseobacterium taklimakanense
comb. nov.
SO INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
LA English
DT Article
ID FLAVOBACTERIUM-MENINGOSEPTICUM; GENUS CHRYSEOBACTERIUM; SEJONGIA-MARINA;
CLASSIFICATION; HETEROGENEITY; HAIFENSE; BREVE
AB The taxonomic classification of 182 phenotypically similar isolates was evaluated using DNA-DNA hybridization and 16S rRNA gene sequence analysis. These bacterial isolates were mainly derived from clinical sources; all were Gram-negative non-fermenters and most were indole-producing. Phenotypically, they resembled species from the genera Chryseobacterium, Elizabethkingia or Empedobacter or belonged to CDC groups Ilc, Ile, Ilh and Ili. Based on these analyses, four novel species are described: Chryseobacterium bernardetii sp. nov. (type strain NCTC 13530(T)=CCUG 60564(T)=CDC G229(T)), Chryseobacterium carnis sp. nov. (type strain NCTC 13525(T)=CCUG 60559(T)=CDC G81(T)), Chryseobacterium lactis sp. nov. (type strain NCTC 11390(T)=CCUG 60566(T)=CDC KC1864(T)) and Chryseobacterium nakagawai sp. nov. (type strain NCTC 13529(T)=CCUG 60563(T)=CDC G41(T)). The new combination Chryseobacterium taklimakanense comb. nov. (type strain NCTC 13490(T)=X-65(T)=CCTCC AB 208154(T)=NRRL B-51322(T)) is also proposed to accommodate the reclassified Planobacterium taklimakanense.
C1 [Holmes, B.] Natl Collect Type Cultures, Hlth Protect Agcy, London NW9 5EQ, England.
[Steigerwalt, A. G.; Nicholson, A. C.] Ctr Dis Control & Prevent, Special Bacteriol Reference Lab, Atlanta, GA 30333 USA.
RP Nicholson, AC (reprint author), Ctr Dis Control & Prevent, Special Bacteriol Reference Lab, Atlanta, GA 30333 USA.
EM agn0@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 25
TC 12
Z9 12
U1 0
U2 1
PU SOC GENERAL MICROBIOLOGY
PI READING
PA MARLBOROUGH HOUSE, BASINGSTOKE RD, SPENCERS WOODS, READING RG7 1AG,
BERKS, ENGLAND
SN 1466-5026
EI 1466-5034
J9 INT J SYST EVOL MICR
JI Int. J. Syst. Evol. Microbiol.
PD DEC
PY 2013
VL 63
BP 4639
EP 4662
DI 10.1099/ijs.0.054353-0
PN 12
PG 24
WC Microbiology
SC Microbiology
GA AA2KB
UT WOS:000330922400042
PM 23934253
ER
PT J
AU Branson, BM
Ginocchio, CC
AF Branson, Bernard M.
Ginocchio, Christine C.
TI Introduction to 2013 Journal of Clinical Virology Supplement on HIV
Testing Algorithms
SO JOURNAL OF CLINICAL VIROLOGY
LA English
DT Editorial Material
C1 [Branson, Bernard M.] Ctr Dis Control & Prevent, Diagnost Lab, Div HIV AIDS Prevent, Atlanta, GA 30333 USA.
[Ginocchio, Christine C.] North Shore LIJ Labs, Lake Success, NY USA.
[Ginocchio, Christine C.] Hofstra North Shore Sch Med, Hempstead, NY USA.
RP Branson, BM (reprint author), Ctr Dis Control & Prevent, Diagnost Lab, Div HIV AIDS Prevent, Atlanta, GA 30333 USA.
EM BBranson@cdc.gov
NR 0
TC 2
Z9 2
U1 0
U2 3
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1386-6532
EI 1873-5967
J9 J CLIN VIROL
JI J. Clin. Virol.
PD DEC
PY 2013
VL 58
SU 1
BP E1
EP E1
DI 10.1016/j.jcv.2013.10.026
PG 1
WC Virology
SC Virology
GA 302AJ
UT WOS:000330573300001
PM 24342467
ER
PT J
AU Hutchinson, AB
Ethridge, SF
Wesolowski, LG
Shrestha, RK
Pentella, M
Bennett, B
Farnham, PG
Sullivan, T
Patel, P
Branson, BM
AF Hutchinson, Angela B.
Ethridge, Steven F.
Wesolowski, Laura G.
Shrestha, Ram K.
Pentella, Michael
Bennett, Berry
Farnham, Paul G.
Sullivan, Timothy
Patel, Pragna
Branson, Bernard M.
TI Costs and outcomes of laboratory diagnostic algorithms for the detection
of HIV
SO JOURNAL OF CLINICAL VIROLOGY
LA English
DT Article
DE HIV testing algorithms; Costs; Cost-effectiveness
ID EMERGENCY-DEPARTMENT; UNITED-STATES; INFECTION; PERFORMANCE; TESTS;
SEROCONVERSION; IMMUNOASSAY; ANTIBODY; DONORS; ASSAY
AB Background: An alternative HIV testing algorithm, designed to improve the detection of acute and early infections and differentiate between HIV-1 and HIV-2 antibodies, has been developed by the Centers for Disease Control and Prevention and the Association of Public Health Laboratories. While it promises greater sensitivity, it also raises concerns about costs.
Objective: We sought to compare the most commonly used algorithm which was developed in 1989, a third-generation (3G) immunoassay (IA) and Western blot confirmatory test, to a newer algorithm. The new algorithm includes either a 3G or a fourth-generation (4G) initial IA, followed by confirmatory testing with a HIV-1 /HIV-2 differentiation IA and, if needed, a nucleic acid amplification test (NAT).
Study design: We conducted an analysis of HIV testing costs from the perspective of the laboratory, and classified costs according to IA testing volume. We developed a decision analytic model, populated with cost data from 17 laboratories and published assay performance data, to compare the cost-effectiveness of the testing algorithms for a cohort of 30,000 specimens with a 1% HIV prevalence and 0.1% acute HIV infection prevalence. Results: Costs were lower in high-volume laboratories regardless of testing algorithm. For specimens confirmed positive for HIV antibody, the alternative algorithm (IA, Multispot) was less costly than the current algorithm (IA, WB); however, there was wide variation in reported testing costs. For our cohort, the alternative algorithm initiated with a 3G IA and 4G IA identified 15 and 25 more HIV infections, respectively, than the 1989 algorithm. In medium-volume laboratories, the 1989 algorithm was more costly and less effective than the alternative algorithm with a 3G IA; in high-volume laboratories, the alternative algorithm with 3G IA costs $162 more per infection detected. The alternative algorithm with 4G instead of 3G incurred an additional cost of $14,400 and $4865 in medium- and high-volume labs, respectively.
Discussion: HIV testing costs varied with IA testing volumes. The additional cost of 4G over 3G IA might be justified by the additional cases of HIV detected and transmissions averted due to earlier detection.
Conclusion: The alternative HIV testing algorithm compares favorably to the 1989 algorithm in terms of cost and effectiveness. Published by Elsevier BY.
C1 [Hutchinson, Angela B.; Ethridge, Steven F.; Wesolowski, Laura G.; Shrestha, Ram K.; Farnham, Paul G.; Patel, Pragna; Branson, Bernard M.] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
[Pentella, Michael] Univ Iowa, State Hyg Lab, Iowa City, IA USA.
[Bennett, Berry] Florida Bur Publ Hlth Labs, Jacksonville, FL USA.
[Sullivan, Timothy] New York State Dept Hlth, Wadsworth Ctr, Albany, NY USA.
RP Hutchinson, AB (reprint author), Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
EM ash2@cdc.gov
OI Sullivan, Timothy/0000-0003-3144-9188
NR 34
TC 8
Z9 8
U1 1
U2 4
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1386-6532
EI 1873-5967
J9 J CLIN VIROL
JI J. Clin. Virol.
PD DEC
PY 2013
VL 58
SU 1
BP E2
EP E7
DI 10.1016/j.jcv.2013.10.005
PG 6
WC Virology
SC Virology
GA 302AJ
UT WOS:000330573300002
PM 24342475
ER
PT J
AU Linley, L
Ethridge, SF
Oraka, E
Owen, SM
Wesolowski, LG
Wroblewski, K
Landgraf, KM
Parker, MM
Brinson, M
Branson, BM
AF Linley, Laurie
Ethridge, Steven F.
Oraka, Emeka
Owen, S. Michele
Wesolowski, Laura G.
Wroblewski, Kelly
Landgraf, Kenneth M.
Parker, Monica M.
Brinson, Myra
Branson, Bernard M.
TI Evaluation of supplemental testing with the Multispot HIV-1/HIV-2 Rapid
Test and APTIMA HIV-1 RNA Qualitative Assay to resolve specimens with
indeterminate or negative HIV-1 Western blots
SO JOURNAL OF CLINICAL VIROLOGY
LA English
DT Article
DE HIV testing; Algorithm; Western blot; HIV-1/HIV-2 Rapid Test; HIV-1 NAT;
Acute HIV infection
ID NUCLEIC-ACID; INFECTION; DIAGNOSIS; TRANSMISSION; IMMUNOASSAY; RATES;
BLOOD
AB Background: The use of Western blot (WB) as a supplemental test after reactive sensitive initial assays can lead to inconclusive or misclassified HIV test results, delaying diagnosis.
Objective: To determine the proportion of specimens reactive by immunoassay (IA) but indeterminate or negative by WB that could be resolved by alternative supplemental tests recommended under a new HIV diagnostic testing algorithm.
Study design: Remnant HIV diagnostic specimens that were reactive on 3rd generation HIV-1/2 IA and either negative or indeterminate by HIV-1 WB from 11 health departments were tested with the Bio-Rad Multispot HIV-1/HIV-2 Rapid Test (Multispot) and the Gen-Probe APTIMA HIV-1 RNA Qualitative Assay (APTIMA).
Results: According to the new testing algorithm, 512 (89.8%) specimens were HIV-negative, 55 (9.6%) were HIV-1 positive (including 19 [3.3%] that were acute HIV-1 and 9 [1.6%] that were positive for HIV-1 by Multispot but APTIMA-negative), 2 (0.4%) were HIV-2 positive, and 1 (0.2%) was HIV-positive, type undifferentiated. 47(21.4%) of the 220 WB-indeterminate and 8(2.3%) of the 350 WB-negative specimens were HIV-1 positive.
Conclusion: Applying the new HIV diagnostic algorithm retrospectively to WB-negative and indeterminate specimens, the HIV infection status could be established for nearly all of the specimens. IA-reactive HIV-infected persons with WB-negative results had been previously misclassified as uninfected, and HIV diagnosis was delayed for those with WB-indeterminate specimens. These findings underscore the limitations of the WB to confirm HIV infection after reactive results from contemporary 3rd or 4th generation IAs that can detect HIV antibodies several weeks sooner than the WB. Published by Elsevier B.V.
C1 [Linley, Laurie; Ethridge, Steven F.; Owen, S. Michele; Wesolowski, Laura G.; Branson, Bernard M.] Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA 30333 USA.
[Oraka, Emeka] ICF Int, Fairfax, VA USA.
[Wroblewski, Kelly; Landgraf, Kenneth M.] Assoc Publ Hlth Labs, Silver Spring, MD USA.
[Parker, Monica M.] New York State Dept Hlth, Wadsworth Ctr, Albany, NY 12237 USA.
RP Linley, L (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd NE,Mailstop E-47, Atlanta, GA 30333 USA.
EM LLinley@cdc.gov
OI Landgraf, Kenneth/0000-0001-5462-0561
FU Centers for Disease Control and Prevention [U60/CD303019]
FX This publication was supported in part by Cooperative Agreement Number
#U60/CD303019 from the Centers for Disease Control and Prevention.
NR 25
TC 5
Z9 5
U1 0
U2 1
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1386-6532
EI 1873-5967
J9 J CLIN VIROL
JI J. Clin. Virol.
PD DEC
PY 2013
VL 58
SU 1
BP E108
EP E112
DI 10.1016/j.jcv.2013.09.021
PG 5
WC Virology
SC Virology
GA 302AJ
UT WOS:000330573300022
PM 24342469
ER
PT J
AU Masciotra, S
Luo, W
Youngpairoj, AS
Kennedy, MS
Wells, S
Ambrose, K
Sprinkle, P
Owen, SM
AF Masciotra, Silvina
Luo, Wei
Youngpairoj, Ae S.
Kennedy, M. Susan
Wells, Susan
Ambrose, Krystin
Sprinkle, Patrick
Owen, S. Michele
TI Performance of the Alere Determine (TM) HIV-1/2 Ag/Ab Combo Rapid Test
with specimens from HIV-1 seroconverters from the US and HIV-2 infected
individuals from Ivory Coast
SO JOURNAL OF CLINICAL VIROLOGY
LA English
DT Article
DE Diagnostic; HIV-1/2; Rapid test; 4th generation
ID DIAGNOSIS; ASSAY
AB Background: FDA-approved HIV Antigen/Antibody combo (4th generation) immunoassays (IAs) can identify HIV-1 infections before the Western blot (WB) becomes positive. In the US, increased detection of acute HIV infections has been facilitated by using 4th generation IAs, but there is no FDA-approved 4th generation rapid test (RT). The Alere Determine (TM) HIV-112 Ag/Ab Combo (Determine Combo) RT detects and distinguishes HIV p24 Antigen (Ag) from Antibody (Ab) to HIV-1 + HIV-2 and thus has the potential to improve diagnosis of acute HIV infection.
Objective: To evaluate the ability of Determine Combo RT to detect acute/early HIV-1 infections and HIV-2 antibody in well-characterized plasma specimens.
Study design: In HIV-1 seroconverters from the US, Determine Combo reactivity was evaluated by performing the 50% cumulative frequency analysis and by comparing with 3rd and 4th generation IAs' reactivity. HIV-2 plasma specimens from Ivory Coast were tested with Determine Combo.
Results: The 50% cumulative frequency analysis in 17 seroconverters placed Determine Combo (Ag+/Ab-, Ag+Ab+, Ag-/Ab+) and Ab-component reactivity at 15.5 and 7 days before WB positivity, respectively. In 26 seroconverters, Determine Combo was reactive in 99.0% and 92.5% of 3rd and 4th generation IAs-reactive specimens, respectively. All HIV-2 plasma specimens were Ab-reactive/Ag-non-reactive by Determine Combo.
Conclusions: Based on previous results with the same seroconversion panels, combined Ag/Ab reactivity of the Determine Combo appears between FDA-approved 4th and 3rd generation laboratory IAs. These data indicate that this RT could detect HIV-1 infection earlier than other RTs and it performs well in HIV-2 specimens. Published by Elsevier B.V.
C1 [Masciotra, Silvina; Luo, Wei; Youngpairoj, Ae S.; Kennedy, M. Susan; Wells, Susan; Ambrose, Krystin; Sprinkle, Patrick; Owen, S. Michele] Ctr Dis Control & Prevent, Branch Lab, Div HIV AIDS Prevent, Atlanta, GA 30333 USA.
RP Masciotra, S (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd NE Mailstop A-25, Atlanta, GA 30333 USA.
EM svm6@cdc.gov
FU Centers for Disease Control intramural
FX Centers for Disease Control intramural fundings.
NR 23
TC 17
Z9 17
U1 1
U2 5
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1386-6532
EI 1873-5967
J9 J CLIN VIROL
JI J. Clin. Virol.
PD DEC
PY 2013
VL 58
SU 1
BP E54
EP E58
DI 10.1016/j.jcv.2013.07.002
PG 5
WC Virology
SC Virology
GA 302AJ
UT WOS:000330573300012
PM 23911678
ER
PT J
AU Masciotra, S
Smith, AJ
Youngpairoj, AS
Sprinkle, P
Miles, I
Sionean, C
Paz-Bailey, G
Johnson, JA
Owen, SM
AF Masciotra, Silvina
Smith, Amanda J.
Youngpairoj, Ae S.
Sprinkle, Patrick
Miles, Isa
Sionean, Catlainn
Paz-Bailey, Gabriela
Johnson, Jeffrey A.
Owen, S. Michele
TI Evaluation of the CDC proposed laboratory HIV testing algorithm among
men who have sex with men (MSM) from five US metropolitan statistical
areas using specimens collected in 2011
SO JOURNAL OF CLINICAL VIROLOGY
LA English
DT Article
DE HIV-1; Diagnostics; Algorithms; Laboratory
ID HIV-1/HIV-2 RAPID TEST; NUCLEIC-ACID; SEROCONVERSION PANELS;
WESTERN-BLOT; P24 ANTIGEN; INFECTION; IMMUNOASSAY; ANTIBODY; RISK;
PREVENTION
AB Background: Until recently most testing algorithms in the United States (US) utilized Western blot (WB) as the supplemental test. CDC has proposed an algorithm for HIV diagnosis which includes an initial screen with a Combo Antigen/Antibody 4th generation-immunoassay (IA), followed by an HIV-112 discriminatory IA of initially reactive-IA specimens. Discordant results in the proposed algorithm are resolved by nucleic acid-amplification testing (NAAT).
Objectives: Evaluate the results obtained with the CDC proposed laboratory-based algorithm using specimens from men who have sex with men (MSM) obtained in five metropolitan statistical areas (MSAs). Study design: Specimens from 992 MSM from five MSAs participating in the CDC's National HIV Behavioral Surveillance System in 2011 were tested at local facilities and CDC. The five MSAs utilized algorithms of various screening assays and specimen types, and WB as the supplemental test. At the CDC, serum/plasma specimens were screened with 4th generation-IA and the Multispot HIV-1/HIV-2 discriminatory assay was used as the supplemental test. NAAT was used to resolve discordant results and to further identify acute HIV infections from all screened-non-reactive missed by the proposed algorithm. Performance of the proposed algorithm was compared to site-specific WB-based algorithms.
Results: The proposed algorithm detected 254 infections. The WB-based algorithms detected 19 fewer infections; 4 by oral fluid (OF) rapid testing and 15 by WB supplemental testing (12 OF and 3 blood). One acute infection was identified by NAAT from all screened-non-reactive specimens.
Conclusions: The proposed algorithm identified more infections than the WB-based algorithms in a highrisk MSM population. OF testing was associated with most of the discordant results between algorithms. HIV testing with the proposed algorithm can increase diagnosis of infected individuals, including early infections. Published by Elsevier B.V.
C1 [Masciotra, Silvina; Smith, Amanda J.; Youngpairoj, Ae S.; Sprinkle, Patrick; Miles, Isa; Sionean, Catlainn; Paz-Bailey, Gabriela; Johnson, Jeffrey A.; Owen, S. Michele] Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA 30333 USA.
RP Masciotra, S (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd NE Mailstop A-25, Atlanta, GA 30333 USA.
EM svm6@cdc.gov
FU Centers for Disease Control and Prevention, National Center for
HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Division of HIV/AIDS
Prevention [PS11-001]
FX This work was supported by the Centers for Disease Control and
Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB
Prevention, Division of HIV/AIDS Prevention Funding Opportunity
Announcement Number PS11-001: National HIV Behavioral Surveillance.
NR 36
TC 9
Z9 10
U1 0
U2 0
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1386-6532
EI 1873-5967
J9 J CLIN VIROL
JI J. Clin. Virol.
PD DEC
PY 2013
VL 58
SU 1
BP E8
EP E12
DI 10.1016/j.jcv.2013.09.002
PG 5
WC Virology
SC Virology
GA 302AJ
UT WOS:000330573300003
PM 24342483
ER
PT J
AU Pandori, MW
Westheimer, E
Gay, C
Moss, N
Fu, J
Hightow-Weidman, LB
Craw, J
Hall, L
Giancotti, FR
Mak, ML
Madayag, C
Tsoi, B
Louie, B
Patel, P
Owen, SM
Peters, PJ
AF Pandori, Mark W.
Westheimer, Emily
Gay, Cindy
Moss, Nicholas
Fu, Jie
Hightow-Weidman, Lisa B.
Craw, Jason
Hall, Laura
Giancotti, Francesca R.
Mak, Mae Ling
Madayag, Carmela
Tsoi, Benjamin
Louie, Brian
Patel, Pragna
Owen, S. Michele
Peters, Philip J.
TI The Multispot rapid HIV-1/HIV-2 differentiation assay is comparable with
the Western blot and an immunofluorescence assay at confirming HIV
infection in a prospective study in three regions of the United States
SO JOURNAL OF CLINICAL VIROLOGY
LA English
DT Article
DE HIV; HIV serodiagnosis; Algorithms
ID DIAGNOSIS; ALGORITHM; TESTS; TRANSMISSION
AB Background: A new HIV diagnostic algorithm has been proposed which replaces the use of the HIV-1 Western blot and HIV-1 immunofluorescence assays (IFA) as the supplemental test with an HIV-1/HIV-2 antibody differentiation assay.
Objectives: To compare an FDA-approved HIV-1/HIV-2 antibody differentiation test (Multispot) as a confirmatory test with the HIV-1 Western blot and IFA.
Study design: Participants were screened with an HIV-1/HIV-2 combination Antigen/Antibody (Ag/Ab) screening assay. Specimens with repeatedly reactive results were tested with Multispot and either Western blot or IFA. Specimens with discordant screening and confirmatory results were resolved with HIV-1 RNA testing.
Results: Individuals (37,876) were screened for HIV infection and 654 (1.7%) had a repeatedly reactive Ag/Ab assay result. On Multispot, 554 (84.7%) were HIV-1 reactive, 0 (0%) were HIV-2 reactive, 1(0.2%) was reactive for both HIV-1 and HIV-2 (undifferentiated), 9 (1.4%) were HIV-1 indeterminate, and 90 (13.8%) were non-reactive. HIV-1 RNA was detected in 47190 Multispot non-reactive (52.2%) specimens. Among specimens confirmed to have HIV infection (true positives), Multispot and Western blot detected HIV-1 antibody in a similar proportion of cases (93.7% vs. 94.4% respectively) while Multispot and IFA also detected HIV-1 antibody in a similar proportion of cases (84.5% vs. 83.4% respectively).
Conclusions: In this study, Multispot confirmed HIV infections at a similar proportion to Western blot and IFA. Multispot, Western blot, and IFA, however, did not confirm all of the reactive Ag/Ab assay results and underscores the importance of HIV NAT testing to resolve discordant screening and confirmatory results. (C) 2013 The Authors. Published by Elsevier B.V. All rights reserved.
C1 [Pandori, Mark W.; Mak, Mae Ling; Madayag, Carmela; Louie, Brian] San Francisco Dept Publ Hlth, San Francisco, CA 94122 USA.
[Westheimer, Emily; Fu, Jie; Giancotti, Francesca R.; Tsoi, Benjamin] New York City Dept Hlth & Mental Hyg, New York, NY USA.
[Gay, Cindy; Hightow-Weidman, Lisa B.] Univ N Carolina, Chapel Hill, NC USA.
[Moss, Nicholas] Alameda Cty Dept Publ Hlth, Oakland, CA USA.
[Craw, Jason; Hall, Laura] ICF Int, Atlanta, GA USA.
[Patel, Pragna; Owen, S. Michele; Peters, Philip J.] Ctr Dis Control & Prevent CDC, Atlanta, GA USA.
RP Pandori, MW (reprint author), San Francisco Dept Publ Hlth, 101 Grove St,Room 419, San Francisco, CA 94122 USA.
EM Mark_Pandori@sfdph.org
FU CDC STOP project
FX CDC STOP project.
NR 16
TC 11
Z9 11
U1 3
U2 5
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1386-6532
EI 1873-5967
J9 J CLIN VIROL
JI J. Clin. Virol.
PD DEC
PY 2013
VL 58
SU 1
BP E92
EP E96
DI 10.1016/j.jcv.2013.10.006
PG 5
WC Virology
SC Virology
GA 302AJ
UT WOS:000330573300019
PM 24342485
ER
PT J
AU Stekler, JD
O'Neal, JD
Lane, A
Swanson, F
Maenza, J
Stevens, CE
Coombs, RW
Dragavon, JA
Swenson, PD
Golden, MR
Branson, BM
AF Stekler, Joanne D.
O'Neal, Joshua D.
Lane, Aric
Swanson, Fred
Maenza, Janine
Stevens, Claire E.
Coombs, Robert W.
Dragavon, Joan A.
Swenson, Paul D.
Golden, Matthew R.
Branson, Bernard M.
TI Relative accuracy of serum, whole blood, and oral fluid HIV tests among
Seattle men who have sex with men
SO JOURNAL OF CLINICAL VIROLOGY
LA English
DT Article
DE HIV testing; Rapid HIV test; Oral fluids
ID ANTIBODY TESTS; INFECTION; SEROCONVERSION; TRANSMISSION; METAANALYSIS;
SENSITIVITY; SPECIMENS; DIAGNOSIS; ASSAYS; PANELS
AB Background: Point-of-care (POC) rapid HIV tests have sensitivity during the "window period" comparable only to earliest generation EIAs. To date, it is unclear whether any POC test performs significantly better than others.
Objective: Compare abilities of POC tests to detect early infection in real time.
Study design: Men who have sex with men (MSM) were recruited into a prospective, cross-sectional study at two HIV testing sites and a research clinic. Procedures compared four POC tests: one performed on oral fluids and three on fingerstick whole blood specimens. Specimens from participants with negative POC results were tested by EIA and pooled nucleic acid amplification testing (NAAT). McNemar's exact tests compared numbers of HIV-infected participants detected.
Results: Between February 2010 and May 2013, 104 men tested HIV-positive during 2479 visits. Eighty-two participants had concordant reactive POC results, 3 participants had concordant non-reactive POC tests but reactive EIAs, and 8 participants had acute infection. Of 12 participants with discordant POC results, OraQuick ADVANCE Rapid HIV-1/2 Antibody Test performed on oral fluids identified fewer infections than OraQuick performed on fingerstick (p=005), Uni-Gold Recombigen HIV test (p=.01), and determine HIV-1/2 Ag/Ab combo (p=005).
Conclusions: These data confirm that oral fluid POC testing detects fewer infections than other methods and is best reserved for circumstances precluding fingerstick or venipuncture. Regardless of specimen type, POC tests failed to identify many HIV-infected MSM in Seattle. In populations with high HIV incidence, the currently approved POC antibody tests are inadequate unless supplemented with p24 antigen tests or NAAT. (C) 2013 Elsevier B.V. All rights reserved.
C1 [Stekler, Joanne D.; O'Neal, Joshua D.; Maenza, Janine; Stevens, Claire E.; Coombs, Robert W.; Golden, Matthew R.] Univ Washington, Dept Med, Seattle, WA USA.
[Stekler, Joanne D.; Golden, Matthew R.] Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA.
[Coombs, Robert W.; Dragavon, Joan A.] Univ Washington, Dept Lab Med, Seattle, WA 98195 USA.
[Stekler, Joanne D.; Lane, Aric; Swenson, Paul D.; Golden, Matthew R.] Publ Hlth Seattle & King Cty, Seattle, WA USA.
[Swanson, Fred] Gay City Hlth Project, Seattle, WA USA.
[Branson, Bernard M.] Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA USA.
RP Stekler, JD (reprint author), Univ Washington, Harborview Med Ctr, Box 359931,325 9th Ave, Seattle, WA 98104 USA.
EM jstekler@uw.edu
OI Lane, Aric/0000-0003-1842-0647
FU NIH [R01 MH-86360, U01 AI-38858, UM1 AI-068618, P30 AI-27757]
FX NIH R01 MH-86360, U01 AI-38858, UM1 AI-068618, and P30 AI-27757.
NR 30
TC 15
Z9 15
U1 1
U2 6
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1386-6532
EI 1873-5967
J9 J CLIN VIROL
JI J. Clin. Virol.
PD DEC
PY 2013
VL 58
SU 1
BP E119
EP E122
DI 10.1016/j.jcv.2013.09.018
PG 4
WC Virology
SC Virology
GA 302AJ
UT WOS:000330573300024
PM 24342471
ER
PT J
AU Emerson, JA
Walden, HS
Peters, RK
Farina, LL
Fredholm, DV
Qvarnstrom, Y
Xayavong, M
Bishop, H
Slapcinsky, J
McIntosh, A
Wellehan, JFX
AF Emerson, Jessica A.
Walden, Heather Stockdale
Peters, Rosanne K.
Farina, Lisa L.
Fredholm, Daniel V.
Qvarnstrom, Yvonne
Xayavong, Maniphet
Bishop, Henry
Slapcinsky, John
McIntosh, Antoinette
Wellehan, James F. X., Jr.
TI Eosinophilic meningoencephalomyelitis in an orangutan (Pongo pygmaeus)
caused by Angiostrongylus cantonensis
SO VETERINARY QUARTERLY
LA English
DT Article
DE orangutan; Pongo pygmaeus; primate; Angiostrongylus cantonensis;
Zachrysia provisoria; meningitis; eosinophilia; rat; real-time PCR
ID MENINGITIS; HAWAII; RATS
C1 [Emerson, Jessica A.; Peters, Rosanne K.; Fredholm, Daniel V.; Wellehan, James F. X., Jr.] Univ Florida, Coll Vet Med, Dept Small Anim Clin Sci, Gainesville, FL 32608 USA.
[Walden, Heather Stockdale; Farina, Lisa L.; McIntosh, Antoinette] Univ Florida, Coll Vet Med, Gainesville, FL 32608 USA.
[Qvarnstrom, Yvonne; Xayavong, Maniphet; Bishop, Henry] Ctr Dis Control & Prevent, Div Parasit Dis & Malaria, Atlanta, GA USA.
[Slapcinsky, John] Univ Florida, Florida Museum Nat Hist, Gainesville, FL 32611 USA.
RP Emerson, JA (reprint author), Univ Florida, Coll Vet Med, Dept Small Anim Clin Sci, 2015 SW 16th Ave, Gainesville, FL 32608 USA.
EM emersonj@ufl.edu
OI Wellehan, Jim/0000-0001-5692-6134
NR 22
TC 5
Z9 5
U1 0
U2 9
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
SN 0165-2176
EI 1875-5941
J9 VET QUART
JI Vet. Q.
PD DEC 1
PY 2013
VL 33
IS 4
BP 191
EP 194
DI 10.1080/01652176.2013.880005
PG 4
WC Veterinary Sciences
SC Veterinary Sciences
GA AA2OC
UT WOS:000330932900003
PM 24512524
ER
PT J
AU Asfaw, A
Rosa, R
Mao, R
AF Asfaw, Abay
Rosa, Roger
Mao, Rebecca
TI Do Zero-Cost Workers' Compensation Medical Claims Really Have Zero
Costs? The Impact of Workplace Injury on Group Health Insurance
Utilization and Costs
SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
LA English
DT Article
ID BACK-PAIN CLAIMS; OCCUPATIONAL INJURY; NARRATIVE ANALYSIS; BENEFITS;
DISABILITY; DISORDERS; ILLNESS; LENGTH; STATES
AB Objective: Previous research suggests that non-workers' compensation (WC) insurance systems, such as group health insurance (GHI), Medicare, or Medicaid, at least partially cover work-related injury and illness costs. This study further examined GHI utilization and costs. Methods: Using two-part model, we compared those outcomes immediately after injuries for which accepted WC medical claims made zero or positive medical payments. Results: Controlling for pre-injury GHI utilization and costs and other covariates, our results indicated that post-injury GHI utilization and costs increased regardless of whether a WC medical claim was zero or positive. The increases were highest for zero-cost WC medical claims. Conclusion: Our national estimates showed that zero-cost WC medical claims alone could cost the GHI $212 million per year.
C1 [Asfaw, Abay; Rosa, Roger; Mao, Rebecca] NIOSH, Off Director, Ctr Dis Control & Prevent, Washington, DC 20201 USA.
RP Asfaw, A (reprint author), NIOSH, Off Director, Ctr Dis Control & Prevent, 395 E St SW, Washington, DC 20201 USA.
EM hqp0@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 26
TC 0
Z9 0
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1076-2752
EI 1536-5948
J9 J OCCUP ENVIRON MED
JI J. Occup. Environ. Med.
PD DEC
PY 2013
VL 55
IS 12
BP 1394
EP 1400
DI 10.1097/JOM.0000000000000030
PG 7
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 300FK
UT WOS:000330449600005
PM 24316724
ER
PT J
AU White, GE
Mazurek, JM
Moorman, JE
AF White, Gretchen E.
Mazurek, Jacek M.
Moorman, Jeanne E.
TI Asthma in Health Care Workers 2008 and 2010 Behavioral Risk Factor
Surveillance System Asthma Call-Back Survey
SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
LA English
DT Article
ID OCCUPATIONAL RISK-FACTORS; NATIONAL-HEALTH; ONSET ASTHMA; PROFESSIONALS;
POPULATION; PREVALENCE; INDUSTRY
AB Objective: To estimate the prevalence of current asthma and the proportion of asthma that is work-related among health care and non-health care workers. Methods: We used 2008 and 2010 Behavioral Risk Factor Surveillance System High Risk/Health Care Worker Module and Asthma Call-Back Survey data collected in 35 states and the District of Columbia to estimate prevalence ratios (PRs). Results: Significantly more health care workers/volunteers than non-health care workers/volunteers with current asthma had asthma attacks (PR = 1.23; 95% confidence interval = 1.03 to 1.46) and asthma symptoms within the past year (PR = 1.07; 95% confidence interval = 1.00 to 1.14). There was no significant difference in the proportion of health care and non-health care workers/volunteers diagnosed with current asthma or work-related asthma. Conclusions: The results of this study are consistent with previous research showing that health care workers with asthma have higher proportions of asthma attacks than non-health care workers.
C1 [White, Gretchen E.; Mazurek, Jacek M.] NIOSH, Ctr Dis Control & Prevent, Morgantown, WV USA.
[Moorman, Jeanne E.] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Atlanta, GA USA.
RP White, GE (reprint author), 1095 Willowdale Rd,MS HG 900, Morgantown, WV 26505 USA.
EM ipb8@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 19
TC 1
Z9 1
U1 1
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1076-2752
EI 1536-5948
J9 J OCCUP ENVIRON MED
JI J. Occup. Environ. Med.
PD DEC
PY 2013
VL 55
IS 12
BP 1463
EP 1468
DI 10.1097/JOM.0000000000000006
PG 6
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 300FK
UT WOS:000330449600015
PM 24270301
ER
PT J
AU Moro, PL
Museru, OI
Broder, K
Cragan, J
Zheteyeva, Y
Tepper, N
Revzina, N
Lewis, P
Arana, J
Barash, F
Kissin, D
Vellozzi, C
AF Moro, Pedro L.
Museru, Oidda I.
Broder, Karen
Cragan, Janet
Zheteyeva, Yenlik
Tepper, Naomi
Revzina, Natalia
Lewis, Paige
Arana, Jorge
Barash, Faith
Kissin, Dmitry
Vellozzi, Claudia
TI Safety of Influenza A (H1N1) 2009 Live Attenuated Monovalent Vaccine in
Pregnant Women
SO OBSTETRICS AND GYNECOLOGY
LA English
DT Article
ID IMMUNIZATION PRACTICES ACIP; ADVISORY-COMMITTEE; UNITED-STATES;
FETAL-DEATH; RECOMMENDATIONS; PREVENTION; COHORT; RISK
AB OBJECTIVE: To characterize maternal and infant outcomes for pregnant women who received live H1N1 influenza vaccine and had no reported adverse events.
METHODS: We identified Vaccine Adverse Event Reporting System reports, which described receipt of live H1N1 vaccine during pregnancy without an indication of an adverse event at the time of the report during October 2009 to June 2010. We reviewed the initial reports and obtained pregnancy outcome and infant data through 6 months of age from medical records. We reviewed the numbers and characteristics of pregnancy complications and infant outcomes including major birth defects and medically important infant conditions. Rates of spontaneous abortion, preterm birth, and major birth defects and their 95% confidence intervals were calculated.
RESULTS: The Vaccine Adverse Event Reporting System received 113 reports stating receipt of live H1N1 vaccine during pregnancy with no adverse events reported. We obtained follow-up maternal records on 95 of the 113 (84%) live H1N1 reports (40.2% were vaccinated in the first trimester) and found: 87 live births (two twin pregnancies) and no maternal deaths occurred. Number and rates of pregnancy-specific adverse events included: 10 (10.5%, 5.8-18.3) spontaneous abortions; four (4.7%, 1.8-11.4) preterm deliveries at 35-36 weeks of gestation; three (3.4%, 1.2-9.7) infants had one or more major birth defects noted at birth: one cleft palate, one cleft lip, and one microtia (underdeveloped or absent external ear). Seven neonates and infants were hospitalized for medically important conditions. One infant death occurred in a 2.5-month-old boy as a result of pertussis.
CONCLUSION: Rates of spontaneous abortion, preterm birth, and major birth defects in pregnant women who received live H1N1 vaccine were similar to or lower than published background rates. No concerning patterns of medical conditions in infants were identified.
C1 Ctr Dis Control & Prevent, Immunizat Safety Off,Natl Ctr Birth Defects & Dev, Div Healthcare Qual Promot,Div Birth Defects & De, Natl Ctr Emerging & Zoonot Infect Dis,Birth Defec, Atlanta, GA 30333 USA.
Ctr Dis Control & Prevent, Womens Hlth & Fertil Branch, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USA.
Emory Sch Med, Dept Pediat, Atlanta, GA USA.
US FDA, Off Biostat & Epidemiol, Ctr Biol Evaluat & Res, Silver Spring, MD USA.
RP Moro, PL (reprint author), Ctr Dis Control & Prevent, Immunizat Safety Off, Div Healthcare Qual Promot, 1600 Clifton Rd,MS D26, Atlanta, GA 30333 USA.
EM pmoro@cdc.gov
FU Centers for Disease Control and Prevention; U.S. Food and Drug
Administration
FX Funded by the Centers for Disease Control and Prevention and the U.S.
Food and Drug Administration.
NR 30
TC 18
Z9 18
U1 0
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0029-7844
EI 1873-233X
J9 OBSTET GYNECOL
JI Obstet. Gynecol.
PD DEC
PY 2013
VL 122
IS 6
BP 1271
EP 1278
DI 10.1097/AOG.0000000000000010
PG 8
WC Obstetrics & Gynecology
SC Obstetrics & Gynecology
GA 300FV
UT WOS:000330450700018
PM 24201689
ER
PT J
AU Mhyre, JM
Shilkrut, A
Kuklina, EV
Callaghan, WM
Creanga, AA
Kaminsky, S
Bateman, BT
AF Mhyre, Jill M.
Shilkrut, Alexander
Kuklina, Elena V.
Callaghan, William M.
Creanga, Andreea A.
Kaminsky, Sari
Bateman, Brian T.
TI Massive Blood Transfusion During Hospitalization for Delivery in New
York State, 1998-2007
SO OBSTETRICS AND GYNECOLOGY
LA English
DT Article
ID POSTPARTUM HEMORRHAGE; OBSTETRIC HEMORRHAGE; MATERNAL MORTALITY;
PLACENTA-ACCRETA; MORBIDITY; CARE; TRENDS; RISK
AB OBJECTIVE: To define the frequency, risk factors, and outcomes of massive transfusion in obstetrics.
METHODS: The State Inpatient Dataset for New York (1998-2007) was used to identify all delivery hospitalizations for hospitals that reported at least one delivery-related transfusion per year. Multivariable logistic regression analysis was performed to examine the relationship between maternal age, race, and relevant clinical variables and the risk of massive blood transfusion defined as 10 or more units of blood recorded.
RESULTS: Massive blood transfusion complicated 6 of every 10,000 deliveries with cases observed even in the smallest facilities. Risk factors with the strongest independent associations with massive blood transfusion included abnormal placentation (1.6/10,000 deliveries, adjusted odds ratio [OR] 18.5, 95% confidence interval [CI] 14.7-23.3), placental abruption (1.0/10,000, adjusted OR 14.6, 95% CI 11.2-19.0), severe preeclampsia (0.8/10,000, adjusted OR 10.4, 95% CI 7.7-14.2), and intrauterine fetal demise (0.7/10,000, adjusted OR 5.5, 95% CI 3.9-7.8). The most common etiologies of massive blood transfusion were abnormal placentation (26.6% of cases), uterine atony (21.2%), placental abruption (16.7%), and postpartum hemorrhage associated with coagulopathy (15.0%). A disproportionate number of women who received a massive blood transfusion experienced severe morbidity including renal failure, acute respiratory distress syndrome, sepsis, and in-hospital death.
CONCLUSION: Massive blood transfusion was infrequent, regardless of facility size. In the presence of known risk for receipt of massive blood transfusion, women should be informed of this possibility, should deliver in a well-resourced facility if possible, and should receive appropriate blood product preparation and venous access in advance of delivery.
C1 Univ Michigan Hlth Syst, Dept Anesthesiol, Ann Arbor, MI USA.
New York Med Coll, Dept Obstet & Gynecol, Valhalla, NY 10595 USA.
Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, Atlanta, GA USA.
Ctr Dis Control & Prevent, Div Reprod Hlth, Atlanta, GA USA.
Harvard Univ, Brigham & Womens Hosp, Sch Med,Dept Med,Div Pharmacoepidemiol & Pharmaco, Dept Anesthesiol Crit Care & Pain Med,Massachuset, Boston, MA 02115 USA.
RP Mhyre, JM (reprint author), Univ Arkansas Med Sci, Dept Anesthesiol, 4301 West Markham St,Slot 515, Little Rock, AR 72205 USA.
EM jmmhyre@uams.edu
FU Intramural CDC HHS [CC999999]
NR 26
TC 21
Z9 22
U1 1
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0029-7844
EI 1873-233X
J9 OBSTET GYNECOL
JI Obstet. Gynecol.
PD DEC
PY 2013
VL 122
IS 6
BP 1288
EP 1294
DI 10.1097/AOG.0000000000000021
PG 7
WC Obstetrics & Gynecology
SC Obstetrics & Gynecology
GA 300FV
UT WOS:000330450700020
PM 24201690
ER
PT J
AU Meza, F
Chen, LL
Hudson, N
AF Meza, Francisco
Chen, Lilia
Hudson, Naomi
TI Investigation of Respiratory and Dermal Symptoms Associated With Metal
Working Fluids at an Aircraft Engine Manufacturing Facility
SO AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
LA English
DT Article
DE metalworking fluid; MWF; thoracic particulates; asthma; dermatitis;
endotoxin; mycobacteria; microbial contamination; fungi; aircraft engine
manufacturing
ID HYPERSENSITIVITY PNEUMONITIS; ASTHMA; EXPOSURE; PREVENTION; PREVALENCE;
DISEASE
AB BackgroundEach year, 1.2 million metalworkers are exposed to metalworking fluids (MWFs), which can cause dermal and respiratory disease. The National Institute for Occupational Safety and Health (NIOSH) conducted a health hazard evaluation of MWF exposures at an aircraft engine manufacturing facility. The objectives were to determine employee exposures to endotoxin and MWFs in the air, characterize symptoms experienced by employees working with MWFs, compare them to symptoms of employees unexposed to MWFs, and make recommendations for reducing exposures based on results.
MethodsFour hundred seven workers were categorized as MWF exposed or MWF unexposed and completed questionnaires. Estimated prevalence ratios (PR) of dermatitis, asthma, and work-related asthma (WRA) symptoms were calculated. Airborne concentrations of MWF and endotoxin were measured, and work practices observed.
ResultsMWF exposed workers had a significantly higher prevalence of dermatitis on wrists/forearms (PR 2.59; 95% CI 1.22, 5.46), asthma symptoms (PR 1.49; 95% CI 1.05, 2.13), and WRA symptoms (PR 2.10; 95% CI 1.22, 3.30) than unexposed workers. Airborne concentrations of MWF were below the NIOSH recommended exposure limit (REL) for MWF aerosols (thoracic particulate mass).
ConclusionsDespite MWF exposures below the NIOSH REL, exposed workers had a higher prevalence of asthma, WRA, and dermatitis symptoms than unexposed workers. Recommendations to reduce exposure included configuring mist collectors to automatically turn on when the machine is in use, and enforcing enclosure use. Am. J. Ind. Med. 56:1394-1401, 2013. (c) 2013 Wiley Periodicals, Inc.
C1 [Meza, Francisco; Chen, Lilia; Hudson, Naomi] NIOSH, Div Surveillance Hazard Evaluat & Field Studies, Cincinnati, OH 45226 USA.
RP Chen, LL (reprint author), NIOSH, Div Surveillance Hazard Evaluat & Field Studies, 4676 Columbia Pkwy,Mailstop R-10, Cincinnati, OH 45226 USA.
EM fto3@cdc.gov
FU National Institute for Occupational Safety and Health
FX Contract grant sponsor: National Institute for Occupational Safety and
Health.
NR 25
TC 3
Z9 3
U1 0
U2 2
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0271-3586
EI 1097-0274
J9 AM J IND MED
JI Am. J. Ind. Med.
PD DEC
PY 2013
VL 56
IS 12
BP 1394
EP 1401
DI 10.1002/ajim.22253
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 294IZ
UT WOS:000330040200003
PM 24122918
ER
PT J
AU Sinclair, RC
Cunningham, TR
Schulte, PA
AF Sinclair, Raymond C.
Cunningham, Thomas R.
Schulte, Paul A.
TI A Model for Occupational Safety and Health Intervention Diffusion to
Small Businesses
SO AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
LA English
DT Article
DE small business; occupational safety; occupational health; intervention
model
ID SMALL ENTERPRISES; SIZE; MANAGEMENT; INDUSTRY; ILLNESS; RISK
AB BackgroundSmaller businesses differ from their larger counterparts in having higher rates of occupational injuries and illnesses and fewer resources for preventing those losses. Intervention models developed outside the United States have addressed the resource deficiency issue by incorporating intermediary organizations such as trade associations.
MethodsThis paper extends previous models by using exchange theory and by borrowing from the diffusion of innovations model. It emphasizes that occupational safety and health (OSH) organizations must understand as much about intermediary organizations as they do about small businesses. OSH organizations (initiators) must understand how to position interventions and information to intermediaries as added value to their relationships with small businesses. Examples from experiences in two midwestern states are used to illustrate relationships and types of analyses implied by the extended model.
ResultsThe study found that intermediary organizations were highly attuned to providing smaller businesses with what they want, including OSH services. The study also found that there are opinion leader organizations and individual champions within intermediaries who are key to decisions and actions about OSH programming.
ConclusionsThe model places more responsibility on both initiators and intermediaries to develop and market interventions that will be valued in the competitive small business environment where the resources required to adopt each new business activity could always be used in other ways. The model is a candidate for empirical validation, and it offers some encouragement that the issue of sustainable OSH assistance to small businesses might be addressed. Am. J. Ind. Med. 56:1442-1451, 2013. Published 2013. This article is a U.S. Government work and is in the public domain in the USA.
C1 [Sinclair, Raymond C.; Cunningham, Thomas R.; Schulte, Paul A.] NIOSH, Ctr Dis Control & Prevent, Educ & Informat Div, Cincinnati, OH 45226 USA.
RP Sinclair, RC (reprint author), NIOSH, 4676 Columbia Pkwy, Cincinnati, OH 45226 USA.
EM rsinclair@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 39
TC 6
Z9 6
U1 2
U2 14
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0271-3586
EI 1097-0274
J9 AM J IND MED
JI Am. J. Ind. Med.
PD DEC
PY 2013
VL 56
IS 12
BP 1442
EP 1451
DI 10.1002/ajim.22263
PG 10
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 294IZ
UT WOS:000330040200008
PM 24115112
ER
PT J
AU Hunter, AS
AF Hunter, Alicia S.
TI Weight of the Nation - Moving Forward, Reversing the Trend
SO JOURNAL OF LAW MEDICINE & ETHICS
LA English
DT Article
C1 Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
RP Hunter, AS (reprint author), Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
NR 1
TC 0
Z9 0
U1 0
U2 1
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1073-1105
EI 1748-720X
J9 J LAW MED ETHICS
JI J. Law Med. Ethics
PD DEC
PY 2013
VL 41
SU 2
SI SI
BP 5
EP 7
DI 10.1111/jlme.12103
PG 3
WC Ethics; Law; Medical Ethics; Medicine, Legal
SC Social Sciences - Other Topics; Government & Law; Medical Ethics; Legal
Medicine
GA 292SO
UT WOS:000329922800001
PM 24446992
ER
PT J
AU Reynolds, MA
Cotwright, CJ
Polhamus, B
Gertel-Rosenberg, A
Chang, D
AF Reynolds, Meredith A.
Cotwright, Caree Jackson
Polhamus, Barbara
Gertel-Rosenberg, Allison
Chang, Debbie
TI Obesity Prevention in the Early Care and Education Setting: Successful
Initiatives across a Spectrum of Opportunities
SO JOURNAL OF LAW MEDICINE & ETHICS
LA English
DT Article
ID TRACKING; CHILDREN
AB With an estimated 12.1% of children aged 2-5 years already obese, prevention efforts must target our youngest children. One of the best places to reach young children for such efforts is the early care and education setting (ECE). More than 11 million U.S. children spend an average of 30 hours per week in ECE facilities. Increased attention at the national, state, and community level on the ECE setting for early obesity prevention efforts has sparked a range of innovative efforts. To assist these efforts, CDC developed a technical assistance and training framework - the Spectrum of Opportunities for Obesity Prevention in the ECE setting - which also served as the organizing framework for the Weight of the Nation ECE track. Participants highlighted their efforts at national, state, and local levels pursuing opportunities on the Spectrum, the standards and best practices that had been the emphasis of their efforts, and common steps for developing, implementing, and evaluating initiatives. Strong leadership and collaboration among a broad group of stakeholders; systematic assessment of needs, opportunities and resources; funding sources; and training and professional development were reported to be integral for successful implementation of standards and best practices, and sustainability.
C1 [Reynolds, Meredith A.] Ctr Dis Control & Prevent, Obes Prevent & Control Branch, Div Nutr Phys Act & Obes, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USA.
[Cotwright, Caree Jackson] Univ Georgia, Coll Family & Consumer Sci, Athens, GA 30602 USA.
[Polhamus, Barbara] Ctr Dis Control & Prevent, Program Dev & Evaluat Branch, Div Nutr Phys Act & Obes, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA.
[Gertel-Rosenberg, Allison] Nemours, Natl Prevent & Practice, Newark, DE USA.
[Chang, Debbie] Nemours, Policy & Prevent, Washington, DC USA.
RP Reynolds, MA (reprint author), Ctr Dis Control & Prevent, Obes Prevent & Control Branch, Div Nutr Phys Act & Obes, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USA.
FU Child Care and Development Fund; Temporary Assistance for Needy
Families, Head Start, Social Service Block Grants; CACFP; Maternal and
Child Health Block Grants
FX States, through their general funds, typically invest in ECE over and
above the allocations they receive from several federal government
programs (e.g., Child Care and Development Fund, Temporary Assistance
for Needy Families, Head Start, Social Service Block Grants, CACFP, and
Maternal and Child Health Block Grants). As of FY 2011, states were
appropriating $18.5 billion of state funds to ECE for services such as
child care, pre-K, home visiting, and other early learning strategies.
33 In many states, the department of education and local school
districts provide funds to support preschool and afterschool child care
providers and expand Head Start programs. In some states, the
legislature has authorized state funds to develop QRIS for ECE.
NR 30
TC 3
Z9 3
U1 0
U2 7
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1073-1105
EI 1748-720X
J9 J LAW MED ETHICS
JI J. Law Med. Ethics
PD DEC
PY 2013
VL 41
SU 2
SI SI
BP 8
EP 18
DI 10.1111/jlme.12104
PG 11
WC Ethics; Law; Medical Ethics; Medicine, Legal
SC Social Sciences - Other Topics; Government & Law; Medical Ethics; Legal
Medicine
GA 292SO
UT WOS:000329922800002
PM 24446993
ER
PT J
AU Foltz, JL
Belay, B
Blackburn, GL
AF Foltz, Jennifer L.
Belay, Brook
Blackburn, George L.
TI Improving the Weight of the Nation by Engaging the Medical Setting in
Obesity Prevention and Control
SO JOURNAL OF LAW MEDICINE & ETHICS
LA English
DT Article
ID HEALTH
AB This manuscript highlights examples of strategies that have made strides in improving the quality of health care environments, systems-level improvements to support self-management, and collaborations between primary care and public health to support effective approaches to prevent obesity among children and adults in the U.S.
C1 [Foltz, Jennifer L.; Belay, Brook] Ctr Dis Control & Prevent, Obes Prevent & Control Branch, Div Nutr Phys Act & Obes, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USA.
[Foltz, Jennifer L.] US Public Hlth Serv Commissioned Corp, Atlanta, GA USA.
[Blackburn, George L.] Harvard Univ, Sch Med, Dept Surg, Beth Israel Deaconess Med Ctr,Ctr Study Nutr Med, Boston, MA 02115 USA.
RP Foltz, JL (reprint author), Ctr Dis Control & Prevent, Obes Prevent & Control Branch, Div Nutr Phys Act & Obes, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USA.
NR 15
TC 1
Z9 1
U1 1
U2 6
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1073-1105
EI 1748-720X
J9 J LAW MED ETHICS
JI J. Law Med. Ethics
PD DEC
PY 2013
VL 41
SU 2
SI SI
BP 19
EP 26
DI 10.1111/jlme.12105
PG 8
WC Ethics; Law; Medical Ethics; Medicine, Legal
SC Social Sciences - Other Topics; Government & Law; Medical Ethics; Legal
Medicine
GA 292SO
UT WOS:000329922800003
PM 24446994
ER
PT J
AU Nihiser, A
Merlo, C
Lee, S
AF Nihiser, Allison
Merlo, Caitlin
Lee, Sarah
TI Preventing Obesity through Schools
SO JOURNAL OF LAW MEDICINE & ETHICS
LA English
DT Article
ID ADOLESCENTS; EDUCATION; HEALTH
AB This paper describes highlights from the Weight of the Nation 2012 Schools Track. Included is a summary of 16 presentations. Presenters shared key actions for obesity prevention through schools. The information provided at the Weight of the Nation can help school health practitioners access tools, apply evidence-based strategies, and model real-world examples to successfully start obesity prevention initiatives in their jurisdiction.
C1 [Nihiser, Allison; Merlo, Caitlin; Lee, Sarah] Ctr Dis Control & Prevent, Div Populat Hlth, Atlanta, GA 30333 USA.
RP Nihiser, A (reprint author), Ctr Dis Control & Prevent, Div Populat Hlth, Atlanta, GA 30333 USA.
FU Intramural CDC HHS [CC999999]
NR 31
TC 0
Z9 0
U1 0
U2 1
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1073-1105
EI 1748-720X
J9 J LAW MED ETHICS
JI J. Law Med. Ethics
PD DEC
PY 2013
VL 41
SU 2
SI SI
BP 27
EP 34
DI 10.1111/jlme.12106
PG 8
WC Ethics; Law; Medical Ethics; Medicine, Legal
SC Social Sciences - Other Topics; Government & Law; Medical Ethics; Legal
Medicine
GA 292SO
UT WOS:000329922800004
PM 24446995
ER
PT J
AU Sommers, JK
Heiser, C
AF Sommers, Janice K.
Heiser, Claire
TI The Role of Community, State, Territorial, and Tribal Public Health in
Obesity Prevention
SO JOURNAL OF LAW MEDICINE & ETHICS
LA English
DT Article
AB This article explores how governmental public health authorities can contribute to public health efforts to address obesity by monitoring the prevalence of obesity and associated risk factors, investigating the contributing factors, informing the public, and working with the citizens in their jurisdiction to develop solutions that fit the needs and sensibilities of the people.
C1 [Sommers, Janice K.] Univ N Carolina, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27515 USA.
[Heiser, Claire] Ctr Dis Control & Prevent, Div Nutr Phys Act & Obes, Atlanta, GA USA.
RP Sommers, JK (reprint author), Univ N Carolina, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27515 USA.
NR 1
TC 0
Z9 0
U1 1
U2 1
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1073-1105
EI 1748-720X
J9 J LAW MED ETHICS
JI J. Law Med. Ethics
PD DEC
PY 2013
VL 41
SU 2
SI SI
BP 35
EP 39
DI 10.1111/jlme.12107
PG 5
WC Ethics; Law; Medical Ethics; Medicine, Legal
SC Social Sciences - Other Topics; Government & Law; Medical Ethics; Legal
Medicine
GA 292SO
UT WOS:000329922800005
PM 24446996
ER
PT J
AU Lankford, T
Lang, J
Bowden, B
Baun, W
AF Lankford, Tina
Lang, Jason
Bowden, Brian
Baun, William
TI Workplace Health: Engaging Business Leaders to Combat Obesity
SO JOURNAL OF LAW MEDICINE & ETHICS
LA English
DT Article
ID COSTS; TIME
AB This article explores how employers can be part of the solution to obesity by offering workplace wellness programs and facilitating opportunities for physical activity, access to healthier foods and beverages, and incentives for disease management and prevention to help prevent weight gain among their employees.
C1 [Bowden, Brian] Ctr Dis Control & Prevent, Off Associate Director Policy, Atlanta, GA USA.
[Baun, William] Houston Wellness Assoc, Board Int Assoc Worksite Hlth Promot, Houston, TX USA.
NR 16
TC 1
Z9 1
U1 3
U2 11
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1073-1105
EI 1748-720X
J9 J LAW MED ETHICS
JI J. Law Med. Ethics
PD DEC
PY 2013
VL 41
SU 2
SI SI
BP 40
EP 45
DI 10.1111/jlme.12108
PG 6
WC Ethics; Law; Medical Ethics; Medicine, Legal
SC Social Sciences - Other Topics; Government & Law; Medical Ethics; Legal
Medicine
GA 292SO
UT WOS:000329922800006
PM 24446997
ER
PT J
AU Trowbridge, MJ
Schmid, TL
AF Trowbridge, Matthew J.
Schmid, Thomas L.
TI Built Environment and Physical Activity Promotion: Place-Based Obesity
Prevention Strategies
SO JOURNAL OF LAW MEDICINE & ETHICS
LA English
DT Article
ID HEALTH; TRAVEL
AB This paper seeks to encourage continued innovation in translating built environment and transportation-focused physical activity research into practice. Successful strategies, policies, and tools from across the U.S. and globally that demonstrate potential for wider-scale implementation are highlighted. The importance of building practice and translational research partnerships with groups and organizations outside traditional public health spheres, such as those who work in real estate and land-use development, is also discussed.
C1 [Trowbridge, Matthew J.] Univ Virginia, Dept Emergency Med, Sch Med, Charlottesville, VA 22903 USA.
[Schmid, Thomas L.] Ctr Dis Control & Prevent, Phys Act & Hlth Branch, Div Nutr Phys Act & Obes, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA.
RP Trowbridge, MJ (reprint author), Univ Virginia, Dept Emergency Med, Sch Med, Charlottesville, VA 22903 USA.
NR 38
TC 4
Z9 4
U1 2
U2 20
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1073-1105
EI 1748-720X
J9 J LAW MED ETHICS
JI J. Law Med. Ethics
PD DEC
PY 2013
VL 41
SU 2
SI SI
BP 46
EP 51
DI 10.1111/jlme.12109
PG 6
WC Ethics; Law; Medical Ethics; Medicine, Legal
SC Social Sciences - Other Topics; Government & Law; Medical Ethics; Legal
Medicine
GA 292SO
UT WOS:000329922800007
PM 24446998
ER
PT J
AU Phiri, S
Zadrozny, S
Weiss, HA
Martinson, F
Nyirenda, N
Chen, CY
Miller, WC
Cohen, MS
Mayaud, P
Hoffman, IF
AF Phiri, Sam
Zadrozny, Sabrina
Weiss, Helen A.
Martinson, Francis
Nyirenda, Naomi
Chen, Cheng-Yen
Miller, William C.
Cohen, Myron S.
Mayaud, Philippe
Hoffman, Irving F.
TI Etiology of Genital Ulcer Disease and Association With HIV Infection in
Malawi
SO SEXUALLY TRANSMITTED DISEASES
LA English
DT Article
ID SIMPLEX-VIRUS TYPE-2; SEXUALLY-TRANSMITTED-DISEASES; HERPES; MANAGEMENT;
TRANSMISSION; ACQUISITION; URETHRITIS; ACYCLOVIR; IMPACT; TRIAL
AB Background: The World Health Organization recommends the use of syndromic management for patients presenting with genital ulcer disease (GUD) in developing countries. However, effective treatment guidelines depend on a current country-specific GUD etiological profile, which may change over time.
Methods: From 2004 to 2006, we conducted a cross-sectional analysis of baseline data from patients presenting with GUD at a reference STI clinic in Lilongwe, Malawi. Participants were enrolled in a randomized clinical trial of acyclovir added to syndromic management and followed up for up to 28 days. Serologies for HIV (using parallel rapid tests), herpes simplex virus type 2 (HSV-2; using Focus HerpeSelect IgG2 ELISA [Focus Technologies, Cypress Hill, CA]), and syphilis (rapid plasma reagin confirmed by Treponema pallidum hemagglutination) were determined, with plasma HIV-1 RNA and CD4 count in HIV-positive patients. Genital ulcer disease etiology was determined by real-time multiplex polymerase chain reaction from lesional swabs.
Results: A total of 422 patients with GUD (313 men; 74%) were enrolled. Overall seroprevalence of HIV-1, HSV-2, and syphilis were 61%, 72%, and 5%, respectively. Ulcer etiology was available for 398 patients and showed the following: HSV-2, 67%; Haemophilus ducreyi, 15%; T. pallidum, 6%; lymphogranuloma venereum, 6%; mixed infections, 14%, and no etiology, 20%. Most HSV-2 ulcers were recurrent (75%). Among all patients with HSV-2, HIV prevalence was high (67%) and HIV seroprevalence was higher among patients with recurrent HSV-2 compared with patients with first-episode HSV-2 (78% vs. 39%, P G 0.001).
Conclusions: Herpes simplex virus type 2 ulcers are highly prevalent in this symptomatic population and strongly associated with HIV. Unlike most locations in sub-Saharan Africa, H. ducreyi remains prevalent in this population and requires periodic monitoring and an appropriate treatment regimen.
C1 [Phiri, Sam] Kamuzu Cent Hosp, Lighthouse Ctr, Lilongwe, Malawi.
[Phiri, Sam; Zadrozny, Sabrina; Miller, William C.; Cohen, Myron S.; Hoffman, Irving F.] Univ N Carolina, Chapel Hill, NC USA.
[Weiss, Helen A.; Martinson, Francis; Nyirenda, Naomi] London Sch Hyg & Trop Med, Infect Dis Epidemiol Unit, London WC1, England.
[Chen, Cheng-Yen] Univ North Carolina Project, Lilongwe, Malawi.
[Chen, Cheng-Yen] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Mayaud, Philippe] London Sch Hyg & Trop Med, Clin Res Unit, London WC1, England.
RP Phiri, S (reprint author), Kamuzu Cent Hosp, Lighthouse Ctr, POB 106, Lilongwe, Malawi.
EM samphiri@lighthouse.org.mw
RI Miller, William/H-4800-2014
OI Miller, William/0000-0002-1934-7827
FU UK Department for International Development through the Malawi National
AIDS Commission; UNC at Chapel Hill, NC
FX The study was funded by the UK Department for International Development
through the Malawi National AIDS Commission and by grants from the UNC
at Chapel Hill, NC. The views expressed are those of the authors and
cannot be taken to reflect the official opinions of the Department for
International Development or of the US CDC.
NR 27
TC 9
Z9 9
U1 0
U2 3
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0148-5717
EI 1537-4521
J9 SEX TRANSM DIS
JI Sex. Transm. Dis.
PD DEC
PY 2013
VL 40
IS 12
BP 923
EP 928
DI 10.1097/OLQ.0000000000000051
PG 6
WC Infectious Diseases
SC Infectious Diseases
GA 297GB
UT WOS:000330242600005
PM 24220352
ER
PT J
AU Burgio, MR
Ioannidis, JPA
Kaminski, BM
DeRycke, E
Rogers, S
Khoury, MJ
Seminara, D
AF Burgio, Michael R.
Ioannidis, John P. A.
Kaminski, Brett M.
DeRycke, Eric
Rogers, Scott
Khoury, Muin J.
Seminara, Daniela
TI Collaborative Cancer Epidemiology in the 21st Century: The Model of
Cancer Consortia
SO CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
LA English
DT Review
ID GENOME-WIDE ASSOCIATION; BRCA2 MUTATION CARRIERS; BRAIN-TUMOR
CONSORTIUM; PROSTATE-CANCER; BREAST-CANCER; GENETIC EPIDEMIOLOGY; FAMILY
REGISTRY; INTERNATIONAL CONSORTIUM; COLON-CANCER; RISK
AB During the last two decades, epidemiology has undergone a rapid evolution toward collaborative research. The proliferation of multi-institutional, interdisciplinary consortia has acquired particular prominence in cancer research. Herein, we describe the characteristics of a network of 49 established cancer epidemiology consortia (CEC) currently supported by the Epidemiology and Genomics Research Program (EGRP) at the National Cancer Institute (NCI). This collection represents the largest disease-based research network for collaborative cancer research established in population sciences. We describe the funding trends, geographic distribution, and areas of research focus. The CEC have been partially supported by 201 grants and yielded 3,876 publications between 1995 and 2011. We describe this output in terms of interdisciplinary collaboration and translational evolution. We discuss challenges and future opportunities in the establishment and conduct of large-scale team science within the framework of CEC, review future prospects for this approach to large-scale, interdisciplinary cancer research, and describe a model for the evolution of an integrated Network of Cancer Consortia optimally suited to address and support 21st-century epidemiology. (C)2013 AACR.
C1 [Burgio, Michael R.; Kaminski, Brett M.; DeRycke, Eric; Rogers, Scott; Khoury, Muin J.; Seminara, Daniela] NCI, Div Canc Control & Populat Sci, Bethesda, MD 20892 USA.
[Khoury, Muin J.] Ctr Dis Control & Prevent, Off Publ Hlth Gen, Atlanta, GA USA.
[Burgio, Michael R.] Sci Consulting Grp Inc, Gaithersburg, MD USA.
[Ioannidis, John P. A.] Stanford Univ, Dept Med, Sch Med, Stanford Prevent Res Ctr, Stanford, CA 94305 USA.
[Ioannidis, John P. A.] Stanford Univ, Sch Med, Dept Publ Hlth & Policy, Stanford, CA 94305 USA.
[Ioannidis, John P. A.] Stanford Univ, Dept Stat, Sch Humanities & Sci, Stanford, CA 94305 USA.
RP Burgio, MR (reprint author), NCI, NIH, Div Canc Control & Populat Sci, Epidemiol & Genom Res Program, 9609 Med Ctr Dr,Rm 4E320,MSC 9763, Rockville, MD 20850 USA.
EM burgiom@mail.nih.gov
FU Intramural CDC HHS [CC999999]; Intramural NIH HHS [Z99 CA999999]
NR 64
TC 5
Z9 5
U1 0
U2 6
PU AMER ASSOC CANCER RESEARCH
PI PHILADELPHIA
PA 615 CHESTNUT ST, 17TH FLOOR, PHILADELPHIA, PA 19106-4404 USA
SN 1055-9965
EI 1538-7755
J9 CANCER EPIDEM BIOMAR
JI Cancer Epidemiol. Biomarkers Prev.
PD DEC
PY 2013
VL 22
IS 12
BP 2148
EP 2160
DI 10.1158/1055-9965.EPI-13-0591
PG 13
WC Oncology; Public, Environmental & Occupational Health
SC Oncology; Public, Environmental & Occupational Health
GA 293ML
UT WOS:000329975700002
PM 24045926
ER
PT J
AU Linton, YM
Pecor, JE
Porter, CH
Mitchell, LB
Garzon-Moreno, A
Foley, DH
Pecor, DB
Wilkerson, RC
AF Linton, Yvonne-Marie
Pecor, James E.
Porter, Charles H.
Mitchell, Luke Brett
Garzon-Moreno, Andres
Foley, Desmond H.
Pecor, David Brooks
Wilkerson, Richard C.
TI Mosquitoes of eastern Amazonian Ecuador: biodiversity, bionomics and
barcodes
SO MEMORIAS DO INSTITUTO OSWALDO CRUZ
LA English
DT Article
DE Ecuador; Amazon; Culicidae; DNA barcodes; species list; habitat
ID ALLIED TAXA DIPTERA; LIFE STAGES; NEOTYPE DESIGNATION; MORPHOLOGICAL
DATA; AEDINI DIPTERA; SOUTH-AMERICA; CULICIDAE; ANOPHELES;
CLASSIFICATION; PHYLOGENY
AB Two snapshot surveys to establish the diversity and ecological preferences of mosquitoes (Diptera: Culicidae) in the terra firme primary rain forest surrounding the Tiputini Biodiversity Station in the UNESCO Yasun Biosphere Reserve of eastern Amazonian Ecuador were carried out in November 1998 and May 1999. The mosquito fauna of this region is poorly known; the focus of this study was to obtain high quality link-reared specimens that could be used to unequivocally confirm species level diversity through integrated systematic study of all life stages and DNA sequences. A total of 2,284 specimens were preserved; 1,671 specimens were link-reared with associated immature exuviae, all but 108 of which are slide mounted. This study identified 68 unique taxa belonging to 17 genera and 27 subgenera. Of these, 12 are new to science and 37 comprise new country records. DNA barcodes [ 658-bp of the mtDNA cytochrome c oxidase (COI) I gene] are presented for 58 individuals representing 20 species and nine genera. DNA barcoding proved useful in uncovering and confirming new species and we advocate an integrated systematics approach to biodiversity studies in future. Associated bionomics of all species collected are discussed. An updated systematic checklist of the mosquitoes of Ecuador (n = 179) is presented for the first time in 60 years.
C1 [Linton, Yvonne-Marie; Pecor, James E.; Foley, Desmond H.; Pecor, David Brooks; Wilkerson, Richard C.] Walter Reed Army Inst Res, Entomol Branch, Silver Spring, MD 20910 USA.
[Linton, Yvonne-Marie; Pecor, James E.; Mitchell, Luke Brett; Garzon-Moreno, Andres; Foley, Desmond H.; Pecor, David Brooks] Smithsonian Inst, Museum Support Ctr, Walter Reed Biosystemat Unit, Suitland, MD USA.
[Porter, Charles H.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Wilkerson, Richard C.] Smithsonian Inst, Dept Entomol, Washington, DC 20560 USA.
RP Linton, YM (reprint author), Walter Reed Army Inst Res, Entomol Branch, Silver Spring, MD 20910 USA.
EM linton.yvonne3@gmail.com
OI Foley, Desmond/0000-0001-7525-4601
FU WRAIR; Smithsonian Institution; National Research Council Senior
Associateship Award
FX WRAIR and the Smithsonian Institution, National Research Council Senior
Associateship Award (to YML), fieldwork supported by University of South
Carolina (to RCW)
NR 60
TC 11
Z9 11
U1 2
U2 13
PU FUNDACO OSWALDO CRUZ
PI RIO DE JANEIRO, RJ
PA AV BRASIL 4365, 21045-900 RIO DE JANEIRO, RJ, BRAZIL
SN 0074-0276
EI 1678-8060
J9 MEM I OSWALDO CRUZ
JI Mem. Inst. Oswaldo Cruz
PD DEC
PY 2013
VL 108
SU 1
BP 100
EP U132
DI 10.1590/0074-0276130440
PG 29
WC Parasitology; Tropical Medicine
SC Parasitology; Tropical Medicine
GA 294ID
UT WOS:000330037800014
PM 24473809
ER
PT J
AU Bailey, RL
Gahche, JJ
Thomas, PR
Dwyer, JT
AF Bailey, Regan L.
Gahche, Jaime J.
Thomas, Paul R.
Dwyer, Johanna T.
TI Why US children use dietary supplements
SO PEDIATRIC RESEARCH
LA English
DT Article
ID UNITED-STATES; NATIONAL-HEALTH; ADULTS; ADOLESCENTS; SAMPLE
AB BACKGROUND: Dietary supplements are used by one-third of children. We examined motivations for supplement use in children, the types of products used by motivations, and the role of physicians and health care practitioners in guiding choices about supplements.
METHODS: We examined motivations for dietary supplement use reported for children (from birth to 19 y of age; n = 8,245) using the National Health and Nutrition Examination Survey 2007-2010.
RESULTS: Dietary supplements were used by 31% of children; many different reasons were given as follows: to "improve overall health" (41%), to "maintain health" (37%), for "supplementing the diet" (23%), to "prevent health problems" (20%), and to "boost immunity" (14%). Most children (similar to 90%) who use dietary supplements use a multivitamin-mineral or multivitamin product. Supplement users tend to be non-Hispanic white, have higher family incomes, report more physical activity, and have health insurance. Only a small group of supplements used by children (15%) were based on the recommendation of a physician or other health care provider.
CONCLUSION: Most supplements used by children are not under the recommendation of a health care provider. The most common reasons for use of supplements in children are for health promotion, yet little scientific data support this notion in nutrient-replete children.
C1 [Bailey, Regan L.; Thomas, Paul R.; Dwyer, Johanna T.] NIH, Off Dietary Supplements, Bethesda, MD 20892 USA.
[Gahche, Jaime J.] Ctr Dis Control & Prevent, Natl Ctr Hlth Stat, Hyattsville, MD 20782 USA.
[Dwyer, Johanna T.] Tufts Univ, Jean Mayer USDA Human Nutr Res Ctr Aging, Boston, MA 02111 USA.
[Dwyer, Johanna T.] Tufts Univ, Sch Med, Boston, MA 02111 USA.
[Dwyer, Johanna T.] Tufts Univ, Friedman Sch Nutr Sci & Policy, Boston, MA 02111 USA.
RP Bailey, RL (reprint author), NIH, Off Dietary Supplements, Bldg 10, Bethesda, MD 20892 USA.
EM baileyr@mail.nih.gov
OI Dwyer, Johanna/0000-0002-0783-1769
FU Office of Dietary Supplements at the National Institutes of Health
FX This work was supported in part by resources from the Office of Dietary
Supplements at the National Institutes of Health.
NR 14
TC 8
Z9 8
U1 3
U2 9
PU NATURE PUBLISHING GROUP
PI NEW YORK
PA 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA
SN 0031-3998
EI 1530-0447
J9 PEDIATR RES
JI Pediatr. Res.
PD DEC
PY 2013
VL 74
IS 6
BP 737
EP 741
DI 10.1038/pr.2013.160
PG 5
WC Pediatrics
SC Pediatrics
GA 287RN
UT WOS:000329560000016
PM 24002333
ER
PT J
AU Wang, DX
Krilich, J
Pellett, S
Baudys, J
Tepp, WH
Barr, JR
Johnson, EA
Kalb, SR
AF Wang, Dongxia
Krilich, Joan
Pellett, Sabine
Baudys, Jakub
Tepp, William H.
Barr, John R.
Johnson, Eric A.
Kalb, Suzanne R.
TI Comparison of the catalytic properties of the botulinum neurotoxin
subtypes A1 and A5
SO BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
LA English
DT Article
DE Botulinum neurotoxin; Mass spectrometry
ID CLOSTRIDIUM-BOTULINUM; SEROTYPE-A; SUBSTRATE RECOGNITION;
NEUROTRANSMITTER RELEASE; SNARE MOTIF; ENDOPEP-MS; SNAP-25; CLEAVAGE;
PROTEOLYSIS; SEQUENCE
AB Clostridium botulinum neurotoxins (BoNTs) cause the life-threatening disease botulism through the inhibition of neurotransmitter release by cleaving essential SNARE proteins. There are seven serologically distinctive types of BoNTs and many subtypes within a serotype have been identified. BoNT/A5 is a recently discovered subtype of type A botulinum neurotoxin which possesses a very high degree of sequence similarity and identity to the well-studied Al subtype. In the present study, we examined the endopeptidase activity of these two BoNT/A subtypes and our results revealed significant differences in substrate binding and cleavage efficiency between subtype AS and Al. Distinctive hydrolysis efficiency was observed between the two toxins during cleavage of the native substrate SNAP-25 versus a shortened peptide mimic. N-terminal truncation studies demonstrated that a key region of the SNAP-25, including the amino acid residues at 151 through 154 located in the remote binding region of the substrate, contributed to the differential catalytic properties between Al and A5. Elevated binding affinity of the peptide substrate resulted from including these important residues and enhanced BoNT/ A5's hydrolysis efficiency. In addition, mutations of these amino add residues affect the proteolytic performance of the two toxins in different ways. This study provides a better understanding of the biological activity of these toxins, their performance characteristics in the Endopep-MS assay to detect BoNT in clinical samples and foods, and is useful for the development of peptide substrates. (C) 2013 The Authors. All rights reserved.
C1 [Wang, Dongxia; Krilich, Joan; Baudys, Jakub; Barr, John R.; Kalb, Suzanne R.] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Div Sci Lab, Atlanta, GA 30341 USA.
[Pellett, Sabine; Tepp, William H.; Johnson, Eric A.] Univ Wisconsin, Dept Bacteriol, Madison, WI 53706 USA.
RP Kalb, SR (reprint author), Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Div Sci Lab, Atlanta, GA 30341 USA.
EM SKalb@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 36
TC 9
Z9 9
U1 1
U2 9
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1570-9639
EI 0006-3002
J9 BBA-PROTEINS PROTEOM
JI BBA-Proteins Proteomics
PD DEC
PY 2013
VL 1834
IS 12
BP 2722
EP 2728
DI 10.1016/j.bbapap2013.09.007
PG 7
WC Biochemistry & Molecular Biology; Biophysics
SC Biochemistry & Molecular Biology; Biophysics
GA 285TQ
UT WOS:000329418300030
PM 24096023
ER
PT J
AU Jefferds, ME
Irizarry, L
Timmer, A
Tripp, K
AF Jefferds, Maria Elena
Irizarry, Laura
Timmer, Arnold
Tripp, Katie
TI UNICEF-CDC global assessment of home fortification interventions 2011:
Current status, new directions, and implications for policy and
programmatic guidance
SO FOOD AND NUTRITION BULLETIN
LA English
DT Article
DE Complementary food supplement; home fortification; intervention;
lipid-based nutrient supplement; micronutrient powders; program guidance
ID FORMATIVE RESEARCH; SUSTAINABILITY; SPRINKLES; ANEMIA
AB Background. Micronutrient powders (MNP) reduce anemia and improve iron status in children aged 6 to 23 months. Little is known about home fortification interventions in low-income and middle-income countries.
Objective. To describe highlights of the Global Assessment of Home Fortification Interventions 2011, new directions, and needed policy and programmatic guidance.
Methods. A cross-sectional survey of home fortification interventions was conducted. Staff at UNICEF and regional focal points at Home Fortification Technical Advisory Group partner agencies sent questionnaires to representatives in 152 low-income and middle-income countries. Included interventions met the following criteria: they were for prevention and used MNP, lipid-based nutrient supplements (LNS), or complementary food supplements (CFS); one recommended mode of use was mixing into food; they were implemented or planning to start within 12 months; and research interventions were directly linked to programs.
Results. This study identified 63 implemented interventions (36 countries) and 28 planned interventions (21 countries), including 34 implemented interventions (22 countries) and 25 planned interventions (20 countries) that used MNR These interventions were expected to reach 17.2 million people in 2011, including 14.1 million participants in MNP interventions. Among implemented interventions, 16% distributed nationally. Most interventions used integrated approaches targeting young children. Recently, there was increasing expansion of interventions in Africa. The main challenges identified were monitoring and evaluation, adherence, product funding, and procurement.
Conclusions. Home fortification interventions, especially those that use MNP, are increasing and scaling up rapidly in regions with widespread problems of micronutrient deficiencies and stunting. Home fortification interventions contribute to global initiatives to reduce undernutrition.
C1 [Jefferds, Maria Elena; Tripp, Katie] US Ctr Dis Control & Prevent, Atlanta, GA USA.
[Irizarry, Laura; Timmer, Arnold] UNICEF, New York, NY USA.
RP Jefferds, ME (reprint author), Ctr Dis Control & Prevent, 4770 Buford Hwy MS-F-77, Atlanta, GA 30341 USA.
EM mjefferds@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 20
TC 9
Z9 9
U1 0
U2 6
PU INT NUTRITION FOUNDATION
PI BOSTON
PA 150 HARRISON AVE, BOSTON, MA 02111 USA
SN 0379-5721
EI 1564-8265
J9 FOOD NUTR BULL
JI Food Nutr. Bull.
PD DEC
PY 2013
VL 34
IS 4
BP 434
EP 443
PG 10
WC Food Science & Technology; Nutrition & Dietetics
SC Food Science & Technology; Nutrition & Dietetics
GA 287QA
UT WOS:000329556100009
PM 24605694
ER
PT J
AU Rowhani-Rahbar, A
Fireman, B
Lewis, E
Nordin, J
Naleway, A
Jacobsen, SJ
Jackson, LA
Tse, A
Belongia, EA
Hambidge, SJ
Weintraub, E
Baxter, R
Klein, NP
AF Rowhani-Rahbar, Ali
Fireman, Bruce
Lewis, Edwin
Nordin, James
Naleway, Allison
Jacobsen, Steven J.
Jackson, Lisa A.
Tse, Alison
Belongia, Edward A.
Hambidge, Simon J.
Weintraub, Eric
Baxter, Roger
Klein, Nicola P.
TI Effect of Age on the Risk of Fever and Seizures Following Immunization
With Measles-Containing Vaccines in Children
SO JAMA PEDIATRICS
LA English
DT Article
ID SAFETY DATALINK PROJECT; FEBRILE SEIZURES; VARICELLA VACCINE; ADVERSE
EVENTS; COMBINATION MEASLES; ACTIVE SURVEILLANCE; RUBELLA VACCINE;
MUMPS; IMMUNOGENICITY; PERTUSSIS
AB IMPORTANCE The first dose of live attenuated measles-containing vaccines is associated with an increased risk of febrile seizures 7 to 10 days following immunization among 12-to 23-month-old children. The combination measles, mumps, rubella, and varicella vaccine is associated with a 2-fold increased risk of febrile seizures 7 to 10 days following immunization compared with the separately administered measles, mumps, and rubella and varicella vaccines. It is unknown whether the magnitude of these increased risks depends on age at immunization.
OBJECTIVE To examine the potential modifying effect of age on the risk of fever and seizures following immunization with measles-containing vaccines.
DESIGN, SETTING, AND PARTICIPANTS Retrospective cohort study at 8 Vaccine Safety Datalink sites of a total of 840 348 children 12 to 23 months of age who had received a measles-containing vaccine from 2001 through 2011.
EXPOSURES Any measles-containing vaccines and measles-containing vaccines by type.
MAIN OUTCOMES AND MEASURES Fever and seizure events occurring during a 42-day postimmunization observation period.
RESULTS In the analysis of any measles-containing vaccines, the increased risk of seizures during the 7-to 10-day risk interval, using the remainder of the observation period as the control interval, was significantly greater among older children (relative risk, 6.5; 95% CI, 5.3-8.1; attributable risk, 9.5 excess cases per 10 000 doses; 95% CI, 7.6-11.5) than among younger children (relative risk, 3.4; 95% CI, 3.0-3.9; attributable risk = 4.0 excess cases per 10 000 doses; 95% CI, 3.4-4.6). The relative risk of postimmunization fever was significantly greater among older children than among younger children; however, its attributable risk was not. In the analysis of vaccine type, measles, mumps, rubella, and varicella vaccine was associated with a 1.4-fold increase in the risk of fever and 2-fold increase in the risk of seizures compared with measles, mumps, and rubella vaccine administered with or without varicella vaccine in both younger and older children.
CONCLUSIONS AND RELEVANCE Measles-containing vaccines are associated with a lower increased risk of seizures when administered at 12 to 15 months of age. Findings of this study that focused on safety outcomes highlight the importance of timely immunization of children with the first dose of measles-containing vaccines.
C1 [Rowhani-Rahbar, Ali; Fireman, Bruce; Lewis, Edwin; Baxter, Roger; Klein, Nicola P.] Kaiser Permanente Vaccine Study Ctr, Oakland, CA USA.
[Nordin, James] HealthPartners Inst Educ & Res, Minneapolis, MN USA.
[Naleway, Allison] Kaiser Permanente Ctr Hlth Res, Portland, OR USA.
[Jacobsen, Steven J.] Kaiser Permanente Dept Res & Evaluat, Pasadena, CA USA.
[Jackson, Lisa A.] Grp Hlth Res Inst, Seattle, WA USA.
[Tse, Alison] Harvard Pilgrim Hlth Care Inst, Dept Populat Med, Boston, MA USA.
[Belongia, Edward A.] Marshfield Clin Res Fdn, Marshfield, WI USA.
[Hambidge, Simon J.] Kaiser Permanente Inst Hlth Res, Denver, CO USA.
[Weintraub, Eric] Ctr Dis Control & Prevent, Immunizat Safety Off, Atlanta, GA USA.
RP Rowhani-Rahbar, A (reprint author), Univ Washington, Dept Epidemiol, POB 357236, Seattle, WA 98195 USA.
EM rowhani@uw.edu
OI Naleway, Allison/0000-0001-5747-4643; Jacobsen,
Steven/0000-0002-8174-8533
FU CDC-sponsored VSD through America's Health Insurance Plans
[200-2002-00732]
FX This study was supported by the CDC-sponsored VSD through a subcontract
(200-2002-00732) with America's Health Insurance Plans.
NR 28
TC 24
Z9 25
U1 2
U2 8
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 515 N STATE ST, CHICAGO, IL 60654-0946 USA
SN 2168-6203
EI 2168-6211
J9 JAMA PEDIATR
JI JAMA Pediatr.
PD DEC
PY 2013
VL 167
IS 12
BP 1111
EP 1117
DI 10.1001/jamapediatrics.2013.2745
PG 7
WC Pediatrics
SC Pediatrics
GA 291QY
UT WOS:000329845300009
PM 24126936
ER
PT J
AU Anderson, WL
Wiener, JM
Khatutsky, G
Armour, BS
AF Anderson, Wayne L.
Wiener, Joshua M.
Khatutsky, Galina
Armour, Brian S.
TI Obesity and people with disabilities: The implications for health care
expenditures
SO OBESITY
LA English
DT Article
ID BODY-MASS INDEX; RISK-FACTORS; US ADULTS; OVERWEIGHT; PREVALENCE;
MORTALITY; TRENDS; UNDERWEIGHT
AB Objective This study estimates additional average health care expenditures for overweight and obesity for adults with disabilities vs. without. Design and Methods Descriptive and multivariate methods were used to estimate additional health expenditures by service type, age group, and payer using 2004-2007 Medical Expenditure Panel Survey data. Results In 2007, 37% of community-dwelling Americans with disabilities were obese vs. 27% of the total population. People with disabilities had almost three times ($2,459) the additional average obesity cost of people without disabilities ($889). Prescription drug expenditures for obese people with disabilities were three times as high and outpatient expenditures were 74% higher. People with disabilities in the 45- to 64-year age group had the highest obesity expenditures. Medicare had the highest additional average obesity expenditures among payers. Among people with prescription drug expenditures, obese people with disabilities had nine times the prevalence of diabetes as normal weight people with disabilities. Overweight people with and without disabilities had lower expenditures than normal-weight people with and without disabilities. Conclusions Obesity results in substantial additional health care expenditures for people with disabilities. These additional expenditures pose a serious current and future problem, given the potential for higher obesity prevalence in the coming decade.
C1 [Anderson, Wayne L.; Wiener, Joshua M.; Khatutsky, Galina] RTI Int, Aging Disabil & Long Term Care Program, Res Triangle Pk, NC USA.
[Armour, Brian S.] Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA USA.
RP Anderson, WL (reprint author), RTI Int, Aging Disabil & Long Term Care Program, Res Triangle Pk, NC USA.
EM wlanderson@rti.org
FU Centers for Disease Control and Prevention (CDC) [200-2007-22644, 05]
FX This study was supported by the Centers for Disease Control and
Prevention (CDC) [Contract #200-2007-22644, Task #05]. The findings and
conclusions in this report are those of the author(s) and do not
necessarily represent the official position of the Centers for Disease
Control and Prevention.
NR 39
TC 6
Z9 6
U1 2
U2 6
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1930-7381
EI 1930-739X
J9 OBESITY
JI Obesity
PD DEC
PY 2013
VL 21
IS 12
BP E798
EP E804
DI 10.1002/oby.20531
PG 7
WC Endocrinology & Metabolism; Nutrition & Dietetics
SC Endocrinology & Metabolism; Nutrition & Dietetics
GA 288LT
UT WOS:000329614200036
PM 23804319
ER
PT J
AU Mirabelli, MC
Beavers, SF
Chatterjee, AB
Moorman, JE
AF Mirabelli, Maria C.
Beavers, Suzanne F.
Chatterjee, Arjun B.
Moorman, Jeanne E.
TI Age at asthma onset and subsequent asthma outcomes among adults with
active asthma
SO RESPIRATORY MEDICINE
LA English
DT Article
DE Asthma; Epidemiology; Prevalence; Respiratory health; Surveillance
ID CORONARY-HEART-DISEASE; QUALITY-OF-LIFE; LUNG-FUNCTION;
ATHEROSCLEROSIS-RISK; UNITED-STATES; HEALTH; MORTALITY; SURVEILLANCE;
COMMUNITIES; CHILDHOOD
AB Introduction: Little is known about the extent to which the age at which asthma first began influences respiratory health later in life. We conducted these analyses to examine the relationship between age at asthma onset and subsequent asthma-related outcomes.
Methods: We used data from 12,216 adults with asthma who participated in the 2010 Behavioral Risk Factor Surveillance System Asthma Call-back Survey to describe the distribution of age at asthma onset. Linear regression was used to estimate associations of age at asthma onset with asthma-related outcomes, including symptoms in the past 30 days and asthma-related emergency visits.
Results: Asthma onset before age 16 was reported by an estimated 42% of adults with active asthma, including 14% with onset at 5-9 years of age who reported experiencing any asthma symptoms on 21% of days in the past month. Compared to this group, the percentage of days in the past month with any asthma symptoms was 14.8% higher (95% confidence interval (Cl): 5.4, 24.1) among those whose asthma onset occurred at <1 year. When age at onset occurred at 10 years or older there was little change in the prevalence of asthma-related emergency visits across age at onset categories.
Conclusion: Age at asthma onset may affect subsequent asthma-related outcomes. Published by Elsevier Ltd.
C1 [Mirabelli, Maria C.; Beavers, Suzanne F.; Moorman, Jeanne E.] Ctr Dis Control & Prevent, Air Pollut & Resp Hlth Branch, Div Environm Hazards & Hlth Effects, Natl Ctr Environm Hlth, Atlanta, GA 30341 USA.
[Chatterjee, Arjun B.] Wake Forest Sch Med, Dept Internal Med, Sect Pulm Crit Care Allergy & Immunol Dis, Winston Salem, NC 27157 USA.
RP Mirabelli, MC (reprint author), Ctr Dis Control & Prevent, Air Pollut & Resp Hlth Branch, Div Environm Hazards & Hlth Effects, Natl Ctr Environm Hlth, 4770 Buford Highway NE,Mailstop F-60, Atlanta, GA 30341 USA.
EM zif7@cdc.gov
OI Mirabelli, Maria/0000-0002-3540-0085
FU National Asthma Control Program in the Air Pollution and Respiratory
Health Branch of the National Center for Environmental Health
FX The Asthma Call-back Survey is funded by the National Asthma Control
Program in the Air Pollution and Respiratory Health Branch of the
National Center for Environmental Health. The Asthma Call-back Survey is
jointly administered with the Office of Surveillance, Epidemiology and
Laboratory Services, Division of Behavioral Surveillance; data
collection is managed by BRFSS coordinators in each of the participating
states, the District of Columbia, and Puerto Rico.
NR 32
TC 6
Z9 6
U1 0
U2 3
PU W B SAUNDERS CO LTD
PI LONDON
PA 32 JAMESTOWN RD, LONDON NW1 7BY, ENGLAND
SN 0954-6111
EI 1532-3064
J9 RESP MED
JI Respir. Med.
PD DEC
PY 2013
VL 107
IS 12
BP 1829
EP 1836
DI 10.1016/j.rmed.2013.09.022
PG 8
WC Cardiac & Cardiovascular Systems; Respiratory System
SC Cardiovascular System & Cardiology; Respiratory System
GA 287RA
UT WOS:000329558700003
PM 24139624
ER
PT J
AU Yanamala, N
Kagan, VE
Shvedova, AA
AF Yanamala, Naveena
Kagan, Valerian E.
Shvedova, Anna A.
TI Molecular modeling in structural nano-toxicology: Interactions of
nano-particles with nano-machinery of cells
SO ADVANCED DRUG DELIVERY REVIEWS
LA English
DT Review
DE Molecular interactions; Computational predictions; Nano-bio
interactions; Inhibition of nano-mechanisms; Oxidative damage;
Comparable sizes of nanoparticles
ID WALLED CARBON NANOTUBES; HIV-1 PR INHIBITORS; GLUTATHIONE-S-TRANSFERASE;
METALLOFULLERENOL GD-AT-C-82(OH)(22); DYNAMICS SIMULATION; ELECTRON
TOMOGRAPHY; PROTEIN MACHINES; C-60 FULLERENES; LIPID-BILAYER; KCSA
CHANNEL
AB Over the past two decades, nanotechnology has emerged as a key player in various disciplines of science and technology. Some of the most exciting applications are in the field of biomedicine - for theranostics (for combined diagnostic and therapeutic purposes) as well as for exploration of biological systems. A detailed understanding of the molecular interactions between nanoparticles and biological nano-machinery - macromolecules, membranes, and intracellular organelles - is crucial for obtaining adequate information on mechanisms of action of nanomaterials as well as a perspective on the long term effects of these materials and their possible toxicological outcomes. This review focuses on the use of structure-based computational molecular modeling as a tool to understand and to predict the interactions between nanomaterials and nano-biosystems. We review major approaches and provide examples of computational analysis of the structural principles behind such interactions. A rationale on how nanopartides of different sizes, shape, structure and chemical properties can affect the organization and functions of nano-machinery of cells is also presented. Published by Elsevier B.V.
C1 [Yanamala, Naveena; Shvedova, Anna A.] NIOSH, Pathol & Physiol Res Branch, CDC, Morgantown, WV 26505 USA.
[Kagan, Valerian E.] Univ Pittsburgh, Dept Environm & Occupat Hlth, Ctr Free Radical & Antioxidant Hlth, Pittsburgh, PA USA.
[Shvedova, Anna A.] WVU, Dept Physiol & Pharmacol, Morgantown, WV USA.
RP Shvedova, AA (reprint author), NIOSH, Pathol & Physiol Res Branch, CDC, 1095 Willowdale Rd, Morgantown, WV 26505 USA.
EM ats1@cdc.gov
RI Arumugam, Thirumagal/C-3408-2014
FU NIH [HL70755, U19AI068021]; NORA [3927ZKCY/3927ZJQP]; NTRC
[32927ZJHF/3927ZKNL]; NIOSH [OH008282, 2927ZKCY]
FX This work was supported by NIH (HL70755 and U19AI068021), NORA
(3927ZKCY/3927ZJQP), NTRC (32927ZJHF/3927ZKNL), and NIOSH (OH008282 and
2927ZKCY) grants.
NR 92
TC 17
Z9 18
U1 4
U2 91
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0169-409X
EI 1872-8294
J9 ADV DRUG DELIVER REV
JI Adv. Drug Deliv. Rev.
PD DEC
PY 2013
VL 65
IS 15
BP 2070
EP 2077
DI 10.1016/j.addr.2013.05.005
PG 8
WC Pharmacology & Pharmacy
SC Pharmacology & Pharmacy
GA 286OQ
UT WOS:000329479000013
PM 23726945
ER
PT J
AU Espinel-Ingroff, A
Arendrup, MC
Pfaller, MA
Bonfietti, LX
Bustamante, B
Canton, E
Chryssanthou, E
Cuenca-Estrella, M
Dannaoui, E
Fothergill, A
Fuller, J
Gaustad, P
Gonzalez, GM
Guarro, J
Lass-Florl, C
Lockhart, SR
Meis, JF
Moore, CB
Ostrosky-Zeichner, L
Pelaez, T
Pukinskas, SRBS
St-Germain, G
Szeszs, MW
Turnidge, J
AF Espinel-Ingroff, A.
Arendrup, M. C.
Pfaller, M. A.
Bonfietti, L. X.
Bustamante, B.
Canton, E.
Chryssanthou, E.
Cuenca-Estrella, M.
Dannaoui, E.
Fothergill, A.
Fuller, J.
Gaustad, P.
Gonzalez, G. M.
Guarro, J.
Lass-Floerl, C.
Lockhart, S. R.
Meis, J. F.
Moore, C. B.
Ostrosky-Zeichner, L.
Pelaez, T.
Pukinskas, S. R. B. S.
St-Germain, G.
Szeszs, M. W.
Turnidge, J.
TI Interlaboratory Variability of Caspofungin MICs for Candida spp. Using
CLSI and EUCAST Methods: Should the Clinical Laboratory Be Testing This
Agent?
SO ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
LA English
DT Article
ID EPIDEMIOLOGIC CUTOFF VALUES; TECHNICAL NOTE; SUSCEPTIBILITY;
DISTRIBUTIONS; INFECTION; SECONDARY; FUNGEMIA
AB Although Clinical and Laboratory Standards Institute (CLSI) clinical breakpoints (CBPs) are available for interpreting echinocandin MICs for Candida spp., epidemiologic cutoff values (ECVs) based on collective MIC data from multiple laboratories have not been defined. While collating CLSI caspofungin MICs for 145 to 11,550 Candida isolates from 17 laboratories (Brazil, Canada, Europe, Mexico, Peru, and the United States), we observed an extraordinary amount of modal variability (wide ranges) among laboratories as well as truncated and bimodal MIC distributions. The species-specific modes across different laboratories ranged from 0.016 to 0.5 mu g/ml for C. albicans and C. tropicalis, 0.031 to 0.5 mu g/ml for C. glabrata, and 0.063 to 1 mu g/ml for C. krusei. Variability was also similar among MIC distributions for C. dubliniensis and C. lusitaniae. The exceptions were C. parapsilosis and C. guilliermondii MIC distributions, where most modes were within one 2-fold dilution of each other. These findings were consistent with available data from the European Committee on Antimicrobial Susceptibility Testing (EUCAST) (403 to 2,556 MICs) for C. albicans, C. glabrata, C. krusei, and C. tropicalis. Although many factors (caspofungin powder source, stock solution solvent, powder storage time length and temperature, and MIC determination testing parameters) were examined as a potential cause of such unprecedented variability, a single specific cause was not identified. Therefore, it seems highly likely that the use of the CLSI species-specific caspofungin CBPs could lead to reporting an excessive number of wild-type (WT) isolates (e.g., C. glabrata and C. krusei) as either non-WT or resistant isolates. Until this problem is resolved, routine testing or reporting of CLSI caspofungin MICs for Candida is not recommended; micafungin or anidulafungin data could be used instead.
C1 [Espinel-Ingroff, A.] Virginia Commonwealth Univ, Med Ctr, Richmond, VA 23284 USA.
[Arendrup, M. C.] Statens Serum Inst, Dept Microbiol Surveillance & Res, Unit Mycol, DK-2300 Copenhagen, Denmark.
[Pfaller, M. A.] JMI Labs, Iowa City, IA USA.
[Pfaller, M. A.] Univ Iowa, Iowa City, IA USA.
[Bonfietti, L. X.] Adolfo Lutz Inst, Aracatuba City, Brazil.
[Bustamante, B.] Univ Peruana Cayetano Heredia, Inst Med Trop Alexander von Humboldt, Lima, Peru.
[Canton, E.] Hosp Univ La Fe, Ctr Invest, Unidad Microbiol Expt, Valencia, Spain.
[Chryssanthou, E.] Karolinska Univ Hosp, Dept Clin Microbiol, Stockholm, Sweden.
[Cuenca-Estrella, M.] Inst Salud Carlos III, Dept Mycol, Ctr Nacl Microbiol, Madrid, Spain.
[Dannaoui, E.] Inst Pasteur, Ctr Natl Reference Mycoses & Antifong, Unite Mycol Mol, Paris, France.
[Fothergill, A.] Univ Texas Hlth Sci Ctr San Antonio, San Antonio, TX 78229 USA.
[Fuller, J.] Univ Alberta, Edmonton, AB, Canada.
[Gaustad, P.] Aker Univ Hosp, Inst Med Microbiol, Rikshosp, Oslo, Norway.
[Gonzalez, G. M.] Univ Autonoma Nuevo Leon, Monterrey, Nuevo Leon, Mexico.
[Guarro, J.] URV, IISPV, Fac Med, Reus, Spain.
[Lass-Floerl, C.] Med Univ Innsbruck, Div Hyg & Med Microbiol, A-6020 Innsbruck, Austria.
[Lockhart, S. R.] Ctr Dis Control & Prevent, Mycot Dis Branch, Atlanta, GA USA.
[Meis, J. F.] Canisius Wilhelmina Hosp, Dept Med Microbiol & Infect Dis, Nijmegen, Netherlands.
[Meis, J. F.] Radboud Univ Nijmegen, Med Ctr, NL-6525 ED Nijmegen, Netherlands.
[Moore, C. B.] Univ S Manchester Hosp, Mycol Reference Ctr, Educ & Res Ctr, Manchester M20 8LR, Lancs, England.
[Ostrosky-Zeichner, L.] Univ Texas Hlth Sci Ctr Houston, Houston, TX 77030 USA.
[Pelaez, T.] Univ Complutense, Fac Med, Hosp Gen Univ Gregorio Maranon, E-28040 Madrid, Spain.
[Pukinskas, S. R. B. S.] Adolfo Lutz Inst, Fungal Taxon Labs, Sao Paulo, Brazil.
[St-Germain, G.] Inst Natl Sante Publ Quebec, Lab Sante Publ Quebec, Quebec City, PQ, Canada.
[Szeszs, M. W.] Adolfo Lutz Inst, Dept Mycol, Sao Paulo, Brazil.
[Turnidge, J.] Univ Adelaide, Adelaide, SA, Australia.
RP Espinel-Ingroff, A (reprint author), Virginia Commonwealth Univ, Med Ctr, Richmond, VA 23284 USA.
EM avingrof@vcu.edu
OI Guarro, Josep/0000-0002-7839-7568
NR 22
TC 71
Z9 72
U1 0
U2 5
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0066-4804
EI 1098-6596
J9 ANTIMICROB AGENTS CH
JI Antimicrob. Agents Chemother.
PD DEC
PY 2013
VL 57
IS 12
BP 5836
EP 5842
DI 10.1128/AAC.01519-13
PG 7
WC Microbiology; Pharmacology & Pharmacy
SC Microbiology; Pharmacology & Pharmacy
GA 279KW
UT WOS:000328959900007
PM 24018263
ER
PT J
AU Ndao, M
Nath-Chowdhury, M
Sajid, M
Marcus, V
Mashiyama, ST
Sakanari, J
Chow, E
Mackey, Z
Land, KM
Jacobson, MP
Kalyanaraman, C
McKerrow, JH
Arrowood, MJ
Caffrey, CR
AF Ndao, Momar
Nath-Chowdhury, Milli
Sajid, Mohammed
Marcus, Victoria
Mashiyama, Susan T.
Sakanari, Judy
Chow, Eric
Mackey, Zachary
Land, Kirkwood M.
Jacobson, Matthew P.
Kalyanaraman, Chakrapani
McKerrow, James H.
Arrowood, Michael J.
Caffrey, Conor R.
TI A Cysteine Protease Inhibitor Rescues Mice from a Lethal Cryptosporidium
parvum Infection
SO ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
LA English
DT Article
ID RANDOMIZED-CONTROLLED-TRIAL; PLASMODIUM-FALCIPARUM; PARASITIC DISEASES;
TOXOPLASMA-GONDII; TRYPANOSOMA-CRUZI; ZAMBIAN CHILDREN; VINYL SULFONES;
CELL INVASION; KNOCKOUT MICE; NITAZOXANIDE
AB Cryptosporidiosis, caused by the protozoan parasite Cryptosporidium parvum, can stunt infant growth and can be lethal in immunocompromised individuals. The most widely used drugs for treating cryptosporidiosis are nitazoxanide and paromomycin, although both exhibit limited efficacy. To investigate an alternative approach to therapy, we demonstrate that the clan CA cysteine protease inhibitor N-methyl piperazine-Phe-homoPhe-vinylsulfone phenyl (K11777) inhibits C. parvum growth in mammalian cell lines in a concentration-dependent manner. Further, using the C57BL/6 gamma interferon receptor knockout (IFN-gamma R-KO) mouse model, which is highly susceptible to C. parvum, oral or intraperitoneal treatment with K11777 for 10 days rescued mice from otherwise lethal infections. Histologic examination of untreated mice showed intestinal inflammation, villous blunting, and abundant intracellular parasite stages. In contrast, K11777-treated mice (210 mg/kg of body weight/day) showed only minimal inflammation and no epithelial changes. Three putative protease targets (termed cryptopains 1 to 3, or CpaCATL-1, -2, and -3) were identified in the C. parvum genome, but only two are transcribed in infected mammals. A homology model predicted that K11777 would bind to cryptopain 1. Recombinant enzymatically active cryptopain 1 was successfully targeted by K11777 in a competition assay with a labeled active-site-directed probe. K11777 exhibited no toxicity in vitro and in vivo, and surviving animals remained free of parasites 3 weeks after treatment. The discovery that a cysteine protease inhibitor provides potent anticryptosporidial activity in an animal model of infection encourages the investigation and development of this biocide class as a new, and urgently needed, chemotherapy for cryptosporidiosis.
C1 [Ndao, Momar; Nath-Chowdhury, Milli] McGill Univ, Res Inst, Natl Reference Ctr Parasitol, Ctr Hlth, Montreal, PQ, Canada.
[Sajid, Mohammed; Sakanari, Judy; Chow, Eric; Mackey, Zachary; Land, Kirkwood M.; McKerrow, James H.; Caffrey, Conor R.] Univ Calif San Francisco, Ctr Discovery & Innovat Parasit Dis, San Francisco, CA 94143 USA.
[Sajid, Mohammed; Sakanari, Judy; Chow, Eric; Mackey, Zachary; Land, Kirkwood M.; McKerrow, James H.; Caffrey, Conor R.] Univ Calif San Francisco, Dept Pathol, Calif Inst Quantitat Biosci, San Francisco, CA 94140 USA.
[Sajid, Mohammed] Leiden Univ, Med Ctr, Leiden, Netherlands.
[Marcus, Victoria] McGill Univ, Montreal Gen Hosp, Ctr Hlth, Dept Pathol, Montreal, PQ H3G 1A4, Canada.
[Land, Kirkwood M.] Univ Pacific, Dept Biol Sci, Stockton, CA 95211 USA.
[Jacobson, Matthew P.; Kalyanaraman, Chakrapani] Univ Calif San Francisco, Dept Pharmaceut Sci, San Francisco, CA 94143 USA.
[Mashiyama, Susan T.; Jacobson, Matthew P.; Kalyanaraman, Chakrapani] Univ Calif San Francisco, Dept Bioengn & Therapeut Sci, San Francisco, CA 94143 USA.
[Arrowood, Michael J.] Ctr Dis Control & Prevent, Div Parasit Dis, Atlanta, GA USA.
RP Ndao, M (reprint author), McGill Univ, Res Inst, Natl Reference Ctr Parasitol, Ctr Hlth, Montreal, PQ, Canada.
EM momar.ndao@mcgill.ca
OI Jacobson, Matthew/0000-0001-6262-655X
FU Sandler Foundation; Foundation of the Montreal General Hospital;
Research Institute of the McGill University Health Centre; PhRMA
Foundation
FX The study was supported by the Sandler Foundation, the Foundation of the
Montreal General Hospital, and the Research Institute of the McGill
University Health Centre. Additional support was provided by the PhRMA
Foundation (a Postdoctoral Fellowship in Informatics to S. T. M.).
NR 74
TC 11
Z9 11
U1 0
U2 5
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0066-4804
EI 1098-6596
J9 ANTIMICROB AGENTS CH
JI Antimicrob. Agents Chemother.
PD DEC
PY 2013
VL 57
IS 12
BP 6063
EP 6073
DI 10.1128/AAC.00734-13
PG 11
WC Microbiology; Pharmacology & Pharmacy
SC Microbiology; Pharmacology & Pharmacy
GA 279KW
UT WOS:000328959900031
PM 24060869
ER
PT J
AU Tamura, D
Nguyen, HT
Sleeman, K
Levine, M
Mishin, VP
Yang, H
Guo, Z
Okomo-Adhiambo, M
Xu, XY
Stevens, J
Gubareva, LV
AF Tamura, Daisuke
Nguyen, Ha T.
Sleeman, Katrina
Levine, Marnie
Mishin, Vasiliy P.
Yang, Hua
Guo, Zhu
Okomo-Adhiambo, Margaret
Xu, Xiyan
Stevens, James
Gubareva, Larisa V.
TI Cell Culture-Selected Substitutions in Influenza A(H3N2) Neuraminidase
Affect Drug Susceptibility Assessment
SO ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
LA English
DT Article
ID RECEPTOR-BINDING VARIANTS; CANINE KIDNEY-CELLS; SIALIC-ACID; MDCK CELLS;
A VIRUSES; LINE VERO; B VIRUSES; RESISTANCE; REPLICATION; INHIBITORS
AB Assessment of drug susceptibility has become an integral part of influenza virus surveillance. In this study, we describe the drug resistance profile of influenza A(H3N2) virus, A/Mississippi/05/2011, collected from a patient treated with oseltamivir and detected via surveillance. An MDCK cell-grown isolate of this virus exhibited highly reduced inhibition by the neuraminidase (NA) inhibitors (NAIs) oseltamivir (8,005-fold), zanamivir (813-fold), peramivir (116-fold), and laninamivir (257-fold) in the NA inhibition assay. Sequence analysis of its NA gene revealed a known oseltamivir-resistance marker, the glutamic acid-to-valine substitution at position 119 (E119V), and an additional change, threonine to isoleucine at position 148 (T148I). Unlike E119V, T148I was not detected in the clinical sample but acquired during viral propagation in MDCK cells. Using recombinant proteins, T148I by itself was shown to cause only a 6-fold increase in the zanamivir 50% inhibitory concentration (IC50) and had no effect on inhibition by other drugs. The T148I substitution reduced NA activity by 50%, most likely by affecting the positioning of the 150 loop at the NA catalytic site. Using pyrosequencing, changes at T148 were detected in 35 (23%) of 150 MDCK cell-grown A(H3N2) viruses tested, which was lower than the frequency of changes at D151 (85%), an NA residue previously implicated in cell selection. We demonstrate that culturing of the A(H3N2) viruses (n = 11) at a low multiplicity of infection delayed the emergence of the NA variants with changes at position 148 and/or 151, especially when conducted in MDCK-SIAT1 cells. Our findings highlight the current challenges in monitoring susceptibility of influenza A(H3N2) viruses to the NAI class of antiviral drugs.
C1 [Tamura, Daisuke; Nguyen, Ha T.; Sleeman, Katrina; Levine, Marnie; Mishin, Vasiliy P.; Yang, Hua; Guo, Zhu; Okomo-Adhiambo, Margaret; Xu, Xiyan; Stevens, James; Gubareva, Larisa V.] Ctr Dis Control & Prevent, Virus Surveillance & Diag Branch, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
[Tamura, Daisuke] Oak Ridge Inst Sci & Educ, Oak Ridge, TN USA.
[Nguyen, Ha T.; Levine, Marnie] Battelle Mem Inst, Atlanta, GA USA.
RP Gubareva, LV (reprint author), Ctr Dis Control & Prevent, Virus Surveillance & Diag Branch, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA.
EM lqg3@cdc.gov
FU Centers for Disease Control and Prevention; Oak Ridge Institute for
Science and Education (ORISE) (Oak Ridge, TN); Business of Innovation
(Battelle, Atlanta, GA)
FX This work was supported by the Centers for Disease Control and
Prevention. Financial support for D. T. for this study was provided by
the Oak Ridge Institute for Science and Education (ORISE) (Oak Ridge,
TN). H.T.N. and M. L. received financial support for this work from the
Business of Innovation (Battelle, Atlanta, GA).
NR 35
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Z9 13
U1 1
U2 3
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0066-4804
EI 1098-6596
J9 ANTIMICROB AGENTS CH
JI Antimicrob. Agents Chemother.
PD DEC
PY 2013
VL 57
IS 12
BP 6141
EP 6146
DI 10.1128/AAC.01364-13
PG 6
WC Microbiology; Pharmacology & Pharmacy
SC Microbiology; Pharmacology & Pharmacy
GA 279KW
UT WOS:000328959900040
PM 24080660
ER
PT J
AU Mucker, EM
Goff, AJ
Shamblin, JD
Grosenbach, DW
Damon, IK
Mehal, JM
Holman, RC
Carroll, D
Gallardo, N
Olson, VA
Clemmons, CJ
Hudson, P
Hruby, DE
AF Mucker, Eric M.
Goff, Arthur J.
Shamblin, Joshua D.
Grosenbach, Douglas W.
Damon, Inger K.
Mehal, Jason M.
Holman, Robert C.
Carroll, Darin
Gallardo, Nadia
Olson, Victoria A.
Clemmons, Cody J.
Hudson, Paul
Hruby, Dennis E.
TI Efficacy of Tecovirimat (ST-246) in Nonhuman Primates Infected with
Variola Virus (Smallpox)
SO ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
LA English
DT Article
ID EXTRACELLULAR ENVELOPED VIRUS; ANTIPOXVIRUS COMPOUND ST-246; VACCINIA
VIRUS; HUMAN VOLUNTEERS; VACCINATION; MODEL; MICE; DISSEMINATION;
CHALLENGE; RESPONSES
AB Naturally occurring smallpox has been eradicated but remains a considerable threat as a biowarfare/bioterrorist weapon (F. Fleck, Bull. World Health Organ. 81: 917-918, 2003). While effective, the smallpox vaccine is currently not recommended for routine use in the general public due to safety concerns (http://www.bt.cdc.gov/agent/smallpox/vaccination). Safe and effective countermeasures, particularly those effective after exposure to smallpox, are needed. Currently, SIGA Technologies is developing the small-molecule oral drug, tecovirimat (previously known as ST-246), as a postexposure therapeutic treatment of orthopoxvirus disease, including smallpox. Tecovirimat has been shown to be efficacious in preventing lethal orthopoxviral disease in numerous animal models (G. Yang, D. C. Pevear, M. H. Davies, M. S. Collett, T. Bailey, et al., J. Virol. 79: 13139-13149, 2005; D. C. Quenelle, R. M. Buller, S. Parker, K. A. Keith, D. E. Hruby, et al., Antimicrob. Agents Chemother., 51: 689-695, 2007; E. Sbrana, R. Jordan, D. E. Hruby, R. I. Mateo, S. Y. Xiao, et al., Am. J. Trop. Med. Hyg. 76: 768 -773, 2007). Furthermore, in clinical trials thus far, the drug appears to be safe, with a good pharmacokinetic profile. In this study, the efficacy of tecovirimat was evaluated in both a prelesional and postlesional setting in nonhuman primates challenged intravenously with 1 x 10(8) PFU of Variola virus (VARV; the causative agent of smallpox), a model for smallpox disease in humans. Following challenge, 50% of placebo-treated controls succumbed to infection, while all tecovirimat-treated animals survived regardless of whether treatment was started at 2 or 4 days postinfection. In addition, tecovirimat treatment resulted in dramatic reductions in dermal lesion counts, oropharyngeal virus shedding, and viral DNA circulating in the blood. Although clinical disease was evident in tecovirimat- treated animals, it was generally very mild and appeared to resolve earlier than in placebo-treated controls that survived infection. Tecovirimat appears to be an effective smallpox therapeutic in nonhuman primates, suggesting that it is reasonably likely to provide therapeutic benefit in smallpox-infected humans.
C1 [Mucker, Eric M.; Goff, Arthur J.; Shamblin, Joshua D.] USAMRIID, Frederick, MD USA.
[Grosenbach, Douglas W.; Hruby, Dennis E.] SIGA Technol Inc, Corvallis, OR USA.
[Damon, Inger K.; Carroll, Darin; Gallardo, Nadia; Olson, Victoria A.; Clemmons, Cody J.; Hudson, Paul] Ctr Dis Control & Prevent CDC, Poxvirus & Rabies Branch, Atlanta, GA USA.
[Mehal, Jason M.; Holman, Robert C.] CDC, Div High Consequence Pathogens & Pathol, Atlanta, GA 30333 USA.
RP Hruby, DE (reprint author), SIGA Technol Inc, Corvallis, OR USA.
EM dhruby@siga.com
FU Defense Threat Reduction Agency (DTRA)
FX The work described herein was supported by the Defense Threat Reduction
Agency (DTRA). Opinions, interpretations, conclusions, and
recommendations are those of the authors and are not necessarily
endorsed by the U.S. Army or the Department of Defense.
NR 34
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Z9 9
U1 1
U2 6
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0066-4804
EI 1098-6596
J9 ANTIMICROB AGENTS CH
JI Antimicrob. Agents Chemother.
PD DEC
PY 2013
VL 57
IS 12
BP 6246
EP 6253
DI 10.1128/AAC.00977-13
PG 8
WC Microbiology; Pharmacology & Pharmacy
SC Microbiology; Pharmacology & Pharmacy
GA 279KW
UT WOS:000328959900053
PM 24100494
ER
PT J
AU Yu, SF
Nakata, A
Gu, GZ
Swanson, NG
Zhou, WH
He, LH
Wang, S
AF Yu Shan Fa
Nakata, Akinori
Gu Gui Zhen
Swanson, Naomi G.
Zhou Wen Hui
He Li Hua
Wang Sheng
TI Co-effect of Demand-control-support Model and Effort-reward Imbalance
Model on Depression Risk Estimation in Humans: Findings from Henan
Province of China
SO BIOMEDICAL AND ENVIRONMENTAL SCIENCES
LA English
DT Article
DE Depression; Work-related stress; Demand-control-support; Effort-reward
imbalance
ID PSYCHOSOCIAL WORK-ENVIRONMENT; JOB-STRESS MODELS; COLLAR WORKERS;
MENTAL-HEALTH; SOCIAL-CLASS; SYMPTOMS; COMPLEMENTARY; EMPLOYEES; STRAIN;
ASSOCIATION
AB Objective To investigate the co-effect of Demand-control-support (DCS) model and Effort-reward Imbalance (ERI) model on the risk estimation of depression in humans in comparison with the effects when they are used respectively.
Methods A total of 3 632 males and 1 706 females from 13 factories and companies in Henan province were recruited in this cross-sectional study. Perceived job stress was evaluated with the Job Content Questionnaire and Effort-Reward Imbalance Questionnaire (Chinese version). Depressive symptoms were assessed by using the Center for Epidemiological Studies Depression Scale (CES-D).
Results DC (demands/job control ratio) and ERI were shown to be independently associated with depressive symptoms. The outcome of low social support and overcommitment were similar. High DC and low social support (SS), high ERI and high overcommitment, and high DC and high ERI posed greater risks of depressive symptoms than each of them did alone. ERI model and SS model seem to be effective in estimating the risk of depressive symptoms if they are used respectively.
Conclusion The DC had better performance when it was used in combination with low SS. The effect on physical demands was better than on psychological demands. The combination of DCS and ERI models could improve the risk estimate of depressive symptoms in humans.
C1 [Yu Shan Fa; Gu Gui Zhen; Zhou Wen Hui] Henan Prov Inst Occupat Hlth, Zhengzhou 450052, Henan, Peoples R China.
[Nakata, Akinori; Swanson, Naomi G.] NIOSH, Cincinnati, OH 45226 USA.
[He Li Hua; Wang Sheng] Peking Univ, Hlth Sci Ctr, Beijing 100191, Peoples R China.
RP Yu, SF (reprint author), Henan Prov Inst Occupat Hlth, Zhengzhou 450052, Henan, Peoples R China.
EM chinas-tress@sina.com
FU Henan Provincial Health Science and Technology Key Projects [201001009];
National Science and Technology Infrastructure Program, China [2006BA
I06B 08]
FX This research was funded by Henan Provincial Health Science and
Technology Key Projects (201001009) and National Science and Technology
Infrastructure Program (2006BA I06B 08), China.
NR 39
TC 4
Z9 9
U1 0
U2 16
PU CHINESE CENTER DISEASE CONTROL & PREVENTION
PI BEIJING
PA 155 CHANGBAI RD, CHANGPING DISTRICT, BEIJING, 102206, PEOPLES R CHINA
SN 0895-3988
J9 BIOMED ENVIRON SCI
JI Biomed. Environ. Sci.
PD DEC
PY 2013
VL 26
IS 12
BP 962
EP 971
DI 10.3967/bes2013.031
PG 10
WC Environmental Sciences; Public, Environmental & Occupational Health
SC Environmental Sciences & Ecology; Public, Environmental & Occupational
Health
GA 286PB
UT WOS:000329480100004
PM 24393505
ER
PT J
AU Meites, E
AF Meites, Elissa
TI Trichomoniasis The "Neglected" Sexually Transmitted Disease
SO INFECTIOUS DISEASE CLINICS OF NORTH AMERICA
LA English
DT Article
DE Trichomonas vaginalis; Vaginitis; Urethritis; Nucleic acid amplification
tests; Nitroimidazoles; Sexually transmitted disease
ID HUMAN-IMMUNODEFICIENCY-VIRUS; RANDOMIZED CONTROLLED-TRIAL; VAGINALIS
INFECTION; UNITED-STATES; CHLAMYDIA-TRACHOMATIS; AMPLIFICATION ASSAY;
PROSTATE-CANCER; WET PREPARATION; CLINICAL-TRIAL; AFRICAN WOMEN
AB Trichomonas vaginalis is the most prevalent nonviral sexually transmitted infection, affecting an estimated 3.7 million people in the United States. Although trichomoniasis is common, it has been considered a "neglected" sexually transmitted disease, due to limited knowledge of its sequelae and associated costs. This article reviews current epidemiology, pathophysiology, diagnostic methods, clinical management recommendations and special considerations, research on associated conditions and costs, prevention strategies, and controversies regarding trichomoniasis.
C1 Ctr Dis Control & Prevent, Div STD Prevent, Natl Ctr HIV Viral Hepatitis STD & TB Prevent, Atlanta, GA 30333 USA.
RP Meites, E (reprint author), Ctr Dis Control & Prevent, Div STD Prevent, Natl Ctr HIV Viral Hepatitis STD & TB Prevent, 1600 Clifton Rd Northeast,MS E-02, Atlanta, GA 30333 USA.
EM emeites@cdc.gov
OI Meites, Elissa/0000-0002-0077-2591
FU Intramural CDC HHS [CC999999]
NR 53
TC 8
Z9 8
U1 0
U2 12
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0891-5520
EI 1557-9824
J9 INFECT DIS CLIN N AM
JI Infect. Dis. Clin. North Am.
PD DEC
PY 2013
VL 27
IS 4
BP 755
EP +
DI 10.1016/j.idc.2013.06.003
PG 11
WC Immunology; Infectious Diseases
SC Immunology; Infectious Diseases
GA 281FW
UT WOS:000329086400005
PM 24275268
ER
PT J
AU Dunne, EF
Park, IU
AF Dunne, Eileen F.
Park, Ina U.
TI HPV and HPV-Associated Diseases
SO INFECTIOUS DISEASE CLINICS OF NORTH AMERICA
LA English
DT Article
DE HPV; Anogenital warts; Genital warts; HPV-associated diseases; Cervical
cancer; HPV vaccines
ID HUMAN-PAPILLOMAVIRUS INFECTION; GENITAL HUMAN-PAPILLOMAVIRUS; CERVICAL
INTRAEPITHELIAL NEOPLASIA; AGE-SPECIFIC PREVALENCE; UNITED-STATES;
YOUNG-WOMEN; NATURAL-HISTORY; HETEROSEXUAL COUPLES; ANAL CANCER;
VACCINATION COVERAGE
AB Human papillomavirus (HPV) is the most common sexually transmitted infection. HPV is associated with a significant burden of disease and cancer, including anogenital warts and recurrent respiratory papillomatosis, and anogenital and oropharyngeal cancers. Effective prevention is available, including primary prevention of cancers and anogenital warts through HPV vaccination, and secondary prevention of cervical cancer through screening and treatment of precancer. This article focuses on HPV infection and the clinical consequences of infection, with attention to cervical and anogenital squamous intraepithelial neoplasia and anogenital warts.
C1 [Dunne, Eileen F.] Ctr Dis Control & Prevent, Div STD Prevent, Atlanta, GA 30030 USA.
[Park, Ina U.] Univ Calif San Francisco, Sch Med, Dept Family & Community Med, San Francisco, CA 94110 USA.
[Park, Ina U.] Calif STD HIV Prevent Training Ctr, Oakland, CA 94612 USA.
RP Dunne, EF (reprint author), Ctr Dis Control & Prevent, Div STD Prevent, 1600 Clifton Rd,MS E-02, Atlanta, GA 30030 USA.
EM Dde9@cdc.gov
NR 62
TC 19
Z9 20
U1 0
U2 5
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0891-5520
EI 1557-9824
J9 INFECT DIS CLIN N AM
JI Infect. Dis. Clin. North Am.
PD DEC
PY 2013
VL 27
IS 4
BP 765
EP +
DI 10.1016/j.idc.2013.09.001
PG 15
WC Immunology; Infectious Diseases
SC Immunology; Infectious Diseases
GA 281FW
UT WOS:000329086400006
PM 24275269
ER
PT J
AU Miko, A
Delannoy, S
Fach, P
Strockbine, NA
Lindstedt, BA
Mariani-Kurkdjian, P
Reetz, J
Beutin, L
AF Miko, Angelika
Delannoy, Sabine
Fach, Patrick
Strockbine, Nancy A.
Lindstedt, Bjorn Arne
Mariani-Kurkdjian, Patricia
Reetz, Jochen
Beutin, Lothar
TI Genotypes and virulence characteristics of Shiga toxin-producing
Escherichia coli 0104 strains from different origins and sources
SO INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
LA English
DT Article
DE E. coli 0104; Shiga-toxins; Enteroaggregative E. coli; Virulence;
Genotyping; PFGE; Real time PCR; Cell-adhesion
ID HEMOLYTIC-UREMIC SYNDROME; ANTIGEN GENE-CLUSTER; REAL-TIME PCR; O104/H4
STRAINS; OUTBREAK STRAIN; STEC STRAINS; GERMANY; SEQUENCE;
PATHOGENICITY; EXPRESSION
AB Sixty-two Escherichia colt strains carrying the wzx(O104)-gene from different sources, origins and time periods were analyzed for their serotypes, virulence genes and compared for genomic similarity by pulsed-field gel-electrophoresis (PFGE). The 0104 antigen was present in 55 strains and the structurally and genetically related capsular antigen K9 in five strains. The presence of 49 genes associated with enteropathogenic E. coli (EPEC), enteroaggregative E. colt (EAEC) and enterohemorrhagic E. colt (EHEC) was investigated. Fifty-four strains of serotypes 0104:H2 (n = 1), 0104:H4 (n =37), 0104:H7 (n =5) and 0104:H21 (n = 11) produced Shiga-toxins (Stx). Among STEC 0104, a close association between serotype, virulence gene profile and genomic similarity was found. EAEC virulence genes were only present in STEC 0104:H4 strains. EHEC-0157 plasmid-encoded genes were only found in STEC 0104:H2, 0104:H7 and 0104:H21 strains. None of the 62 0104 or 1(9 strains carried an eae-gene involved in the attaching and effacing phenotype.
The 38 0104:H4 strains formed a single PFGE-cluster (>83.7% similarity). Thirty-one of these strains were from the European 0104:H4 outbreak in 2011. The outbreak strains and older 0104:H4 strains from Germany (2001), Georgia and France (2009) clustered together at >86.2% similarity. 0104:H4 strains isolated between 2001 and 2009 differed for some plasmid-encoded virulence genes compared to the outbreak strains from 2011.
STEC 0104:H21 and STEC 0104:H7 strains isolated in the U.S. and in Europe showed characteristic differences in their Stx-types, virulence gene and PFGE profiles indicating that these have evolved separately. E. colt 1(9 strains were not associated with virulence and were-heterogeneous for their serotypes and PFGE profiles. (C) 2013 Elsevier GmbH. All rights reserved.
C1 [Miko, Angelika; Reetz, Jochen; Beutin, Lothar] Fed Inst Risk Assessment, Dept Biol Safety, Berlin, Germany.
[Delannoy, Sabine; Fach, Patrick] Anses French Agcy Food Environm & Occupat Hlth &, Food Safety Lab, Maisons Alfort, France.
[Strockbine, Nancy A.] Ctr Dis Control & Prevent, Escherichia & Shigella Reference Unit, Atlanta, GA USA.
[Lindstedt, Bjorn Arne] Norwegian Inst Publ Hlth, Dept Foodborne Infect, Oslo, Norway.
[Mariani-Kurkdjian, Patricia] Hop Robert Debre, AP HP, Ctr Natl Reference Escherichia Coli & Shigella, Microbiol Serv,Lab Associe, F-75019 Paris, France.
RP Beutin, L (reprint author), BfR Fed Inst Risk Assessment, Natl Reference Lab Escherichia Coli, Diedersdorfer Weg 1, D-12277 Berlin, Germany.
EM lothar.beutin@bfr.bund.de
FU food inspection labs in Germany
FX The authors are grateful to Denis Pierard, Brussels, Belgium, Sabine
Schlager, Graz, Austria, Alex Gill, Ottawa, Canada, Wolfgang Witte,
Wernigerode, Germany, Sascha Al-Dahouk, Berlin, Germany, Stefan
Zimmermann, Berlin, Germany, Dietrich Made, Magdeburg, Germany, Detlef
Horn, Krefeld, Germany; Hella Monse, Krefeld, Germany, Andrea Moss,
Oldenburg, Germany and Estelle Loukiades, Lyon, France, for providing E.
coli 0104 strains for the study. We thank Karin Pries, Katja Steege,
Ylanna Burgos, Sabine Haby, Nadine Albrecht and Maria Margarida Vargas
for excellent technical assistance and the colleagues from the BfR
outbreak investigation team as well as from the food inspection labs in
Germany for their active support.
NR 66
TC 13
Z9 14
U1 2
U2 14
PU ELSEVIER GMBH, URBAN & FISCHER VERLAG
PI JENA
PA OFFICE JENA, P O BOX 100537, 07705 JENA, GERMANY
SN 1438-4221
EI 1618-0607
J9 INT J MED MICROBIOL
JI Int. J. Med. Microbiol.
PD DEC
PY 2013
VL 303
IS 8
BP 410
EP 421
DI 10.1016/j.ijmm.2013.05.006
PG 12
WC Microbiology; Virology
SC Microbiology; Virology
GA 277HQ
UT WOS:000328810000002
PM 23777812
ER
PT J
AU Bhat, G
Naumann, RB
AF Bhat, Geeta
Naumann, Rebecca B.
TI Travel-related behaviors, opinions, and concerns of US adult drivers by
race/ethnicity, 2010
SO JOURNAL OF SAFETY RESEARCH
LA English
DT Article
DE Travel behaviors; Transportation; Race; Ethnicity
ID DRIVING CESSATION; OLDER-ADULTS
AB Introduction: The U.S. population is shifting to become both older and more racially and ethnically diverse. Our current understanding of U.S. drivers' travel-related needs and concerns by race/ethnicity is limited. Methods: Data from the 2010 HealthStyles survey, an annual, cross-sectional, national mail-panel survey of persons ages 18 years or older living in the United States, were used to calculate weighted percentages of travel-related behaviors, opinions, and concerns by race/ethnicity. Logistic regression was used to explore associations between race/ethnicity and specific travel-related concerns, while adjusting for other demographic characteristics. Results: Adequate transportation alternatives to driving were reported by a greater percentage of persons in certain minority groups compared to whites (Hispanic: 34.7%; white: 23.4%). Concern for the availability of alternatives to driving in the future was greater among minority groups (black: 57.7%; Hispanic: 473%; other: 50.9%) compared to whites (37.5%). Additionally, among persons with a household income of $25,000 +, minorities were generally more likely than whites to report concern about having alternative transportation options to driving, whereas concern was consistently high among all racial/ethnic groups for those earning less than $25,000 annually. In each racial/ethnic group, more than 10% of persons reported not knowing how they would get around if they could no longer drive. Conclusions: Important variations by race/ethnicity in both travel behaviors and concerns for adequate alternatives to driving were found, revealing the need for further research to better understand reasons for these differences and to identify ways to meet the transportation needs of the changing U.S. population demographics. Impact on Industry: Further research on adequate alternatives to driving and transportation needs is needed. (C) 2013 National Safety Council and Elsevier Ltd. All rights reserved.
C1 [Bhat, Geeta; Naumann, Rebecca B.] Ctr Dis Control & Prevent, Div Unintent Injury Prevent, Natl Ctr Injury Prevent & Control, Atlanta, GA 30096 USA.
RP Bhat, G (reprint author), Ctr Dis Control & Prevent, 4770 Buford Highway NE,MS F-62, Atlanta, GA 30341 USA.
EM GBhat@cdc.gov
NR 16
TC 2
Z9 2
U1 1
U2 4
PU PERGAMON-ELSEVIER SCIENCE LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
SN 0022-4375
EI 1879-1247
J9 J SAFETY RES
JI J. Saf. Res.
PD DEC
PY 2013
VL 47
BP 93
EP 97
DI 10.1016/j.jsr.2013.09.001
PG 5
WC Ergonomics; Public, Environmental & Occupational Health; Social
Sciences, Interdisciplinary; Transportation
SC Engineering; Public, Environmental & Occupational Health; Social
Sciences - Other Topics; Transportation
GA 285UV
UT WOS:000329421400012
PM 24237875
ER
PT J
AU Pan, LP
May, AL
Wethington, H
Dalenius, K
Grummer-Strawn, LM
AF Pan, Liping
May, Ashleigh L.
Wethington, Holly
Dalenius, Karen
Grummer-Strawn, Laurence M.
TI Incidence of Obesity Among Young US Children Living in Low-Income
Families, 2008-2011
SO PEDIATRICS
LA English
DT Article
DE childhood obesity; incidence; preschool age; infancy; population-based
studies; public health
ID CARDIOVASCULAR RISK-FACTORS; BODY-MASS INDEX; CHILDHOOD OBESITY;
UNITED-STATES; ADOLESCENT OVERWEIGHT; PREVALENCE; TRENDS
AB OBJECTIVE: To examine the incidence and reverse of obesity among young low-income children and variations across population subgroups.
METHODS: We included 1.2 million participants in federally funded child health and nutrition programs who were 0 to 23 months old in 2008 and were followed up 24 to 35 months later in 2010-2011. Weight and height were measured. Obesity at baseline was defined as gender-specific weight-for-length >= 95th percentile on the 2000 Centers for Disease Control and Prevention growth charts. Obesity at follow-up was defined as gender-specific BMI-for-age >= 95th percentile. We used a multivariable log-binomial model to estimate relative risk of obesity adjusting for gender, baseline age, race/ethnicity, duration of follow-up, and baseline weight-for-length percentile.
RESULTS: The incidence of obesity was 11.0% after the follow-up period. The incidence was significantly higher among boys versus girls and higher among children aged 0 to 11 months at baseline versus those older. Compared with non-Hispanic whites, the risk of obesity was 35% higher among Hispanics and 49% higher among American Indians (AIs)/Alaska Natives (ANs), but 8% lower among non-Hispanic African Americans. Among children who were obese at baseline, 36.5% remained obese and 63.5% were nonobese at follow-up. The proportion of reversing of obesity was significantly lower among Hispanics and AIs/ANs than that among other racial/ethnic groups.
CONCLUSIONS: The high incidence underscores the importance of early-life obesity prevention in multiple settings for low-income children and their families. The variations within population subgroups suggest that culturally appropriate intervention efforts should be focused on Hispanics and AIs/ANs.
C1 [Pan, Liping; May, Ashleigh L.; Wethington, Holly; Dalenius, Karen; Grummer-Strawn, Laurence M.] Ctr Dis Control & Prevent, Div Nutr Phys Act & Obes, Atlanta, GA 30341 USA.
RP Pan, LP (reprint author), Ctr Dis Control & Prevent, Div Nutr Phys Act & Obes, 4770 Buford Highway,Mail Stop F-77, Atlanta, GA 30341 USA.
EM Lpan@cdc.gov
FU Intramural CDC HHS [CC999999]
NR 28
TC 23
Z9 23
U1 3
U2 19
PU AMER ACAD PEDIATRICS
PI ELK GROVE VILLAGE
PA 141 NORTH-WEST POINT BLVD,, ELK GROVE VILLAGE, IL 60007-1098 USA
SN 0031-4005
EI 1098-4275
J9 PEDIATRICS
JI Pediatrics
PD DEC
PY 2013
VL 132
IS 6
BP 1006
EP 1013
DI 10.1542/peds.2013-2145
PG 8
WC Pediatrics
SC Pediatrics
GA 282IG
UT WOS:000329163900040
PM 24276843
ER
PT J
AU Hampton, LM
Nguyen, DB
Edwards, JR
Budnitz, DS
AF Hampton, Lee M.
Nguyen, Duc B.
Edwards, Jonathan R.
Budnitz, Daniel S.
TI Cough and Cold Medication Adverse Events After Market Withdrawal and
Labeling Revision
SO PEDIATRICS
LA English
DT Article
DE adverse events; drug safety; poisoning; medication errors; drug
packaging; nasal decongestants; expectorants; antitussive agents;
product withdrawals; nonprescription drugs
ID EMERGENCY-DEPARTMENT VISITS; OVER-THE-COUNTER; YOUNG-CHILDREN; POISON
CENTERS; SURVEILLANCE; INGESTIONS
AB BACKGROUND: In October 2007, manufacturers voluntarily withdrew over-the-counter (OTC) infant cough and cold medications (CCMs) from the US market. A year later, manufacturers announced OTC CCM labeling would be revised to warn against OTC CCM use by children aged <4 years. We determined whether emergency department (ED) visits for CCM adverse drug events (ADEs) declined after these interventions.
METHODS: We used National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance data from 2004 to 2011 to estimate the number of ED visits for CCM ADEs before and after each intervention.
RESULTS: Among children aged <2 years, ED visits for CCM ADEs decreased from 4.1% of all ADE ED visits before the market withdrawal to 2.4% of all ADE visits afterward (difference in proportion: -1.7%, 95% confidence interval [CI]: -2.7% to -0.6%). Among children aged 2 to 3 years, ED visits for CCM ADEs decreased from 9.5% of all ADE ED visits before the labeling revision announcement to 6.5% of all ADE visits afterward (difference in proportion: -3.0%, 95% CI: -5.4% to -0.6%). Unsupervised ingestions accounted for 64.3% (95% CI: 51.1% to 77.5%) of CCM ADE ED visits involving children aged <2 years after the withdrawal and 88.8% (95% CI: 83.8% to 93.8%) of visits involving children aged 2 to 3 years after the labeling revision announcement.
CONCLUSIONS: After a voluntary market withdrawal and labeling revision, ED visits for CCM ADEs declined among children aged,2 years and 2 to 3 years relative to ADE ED visits for all drugs. Interventions addressing unsupervised ingestions are needed to reduce CCM ADEs.
C1 [Hampton, Lee M.; Nguyen, Duc B.; Edwards, Jonathan R.; Budnitz, Daniel S.] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA 30329 USA.
[Nguyen, Duc B.] Ctr Dis Control & Prevent, Sci Educ & Profess Dev Program Off, Epidem Intelligence Serv, Atlanta, GA 30329 USA.
RP Hampton, LM (reprint author), Ctr Dis Control & Prevent, 1600 Clifton Rd,MS A-24, Atlanta, GA 30329 USA.
EM lhampton@cdc.gov
FU Emory AIDS International Training and Research Program [NIH/FIC D43
TW01042]
FX We thank Joel Friedman, Thomas Schroeder, Herman Burney, and the
USConsumer Products Safety Commission analysts along with Ray Colucci
and the National Electronic Injury Surveillance System coders for
diligent data collection, Kelly Weidenbach and Katie Rose for data
review and Maribeth Lovegrove for analytic assistance and insightful
comments on the manuscript. Dr Nguyen would like to acknowledge previous
training support from the Emory AIDS International Training and Research
Program (grant NIH/FIC D43 TW01042).
NR 32
TC 12
Z9 12
U1 0
U2 3
PU AMER ACAD PEDIATRICS
PI ELK GROVE VILLAGE
PA 141 NORTH-WEST POINT BLVD,, ELK GROVE VILLAGE, IL 60007-1098 USA
SN 0031-4005
EI 1098-4275
J9 PEDIATRICS
JI Pediatrics
PD DEC
PY 2013
VL 132
IS 6
BP 1047
EP 1054
DI 10.1542/peds.2013-2236
PG 8
WC Pediatrics
SC Pediatrics
GA 282IG
UT WOS:000329163900045
PM 24218462
ER
PT J
AU Holt, MK
Matjasko, JL
Espelage, D
Reid, G
Koenig, B
AF Holt, Melissa K.
Matjasko, Jennifer L.
Espelage, Dorothy
Reid, Gerald
Koenig, Brian
TI Sexual Risk Taking and Bullying Among Adolescents
SO PEDIATRICS
LA English
DT Article
DE bullying; sexual behavior; sexual orientation
ID HIGH-SCHOOL-STUDENTS; SUBSTANCE USE; BEHAVIOR; HEALTH; VICTIMIZATION;
AGGRESSION; CHILDHOOD; ASSOCIATIONS; MALTREATMENT; ORIENTATION
AB BACKGROUND: Psychological and educational correlates of bullying have been explored extensively. However, little information is available about the link between bullying and sexual risk-taking behaviors among adolescents, though for some youth it may be that sexual risk taking emerges in response to bullying involvement. Associations for both heterosexual youth and those who identify as gay, lesbian, bisexual, transgender, or questioning (GLBTQ) should be considered, as should the influence of victimization exposures in other domains. Accordingly, associations among bullying, other victimization forms, and sexual risk-taking behaviors were examined among adolescents with particular consideration to sexual orientation.
METHODS: A sample of 8687 high school students completed the Dane County Youth Survey, a countywide survey administered high school students from 24 schools. Participants were asked questions about their bullying involvement and sexual risk-taking behaviors (ie, engaging in casual sex and having sex while under the influence of alcohol or drugs).
RESULTS: Results indicated that bullies and bully-victims were more likely to engage in casual sex and sex under the influence. In multivariate analyses, these findings held even after controlling for demographic characteristics and victimization exposures in other domains, but primarily for heterosexual youth.
CONCLUSIONS: Bullies and bully-victims engaged in more sexual risk-taking behaviors, although patterns of association varied by sexual orientation. Bullying prevention programs and programs aimed at reducing unhealthy sexual practices should consider a broader stress and coping perspective and address the possible link between the stress of bullying involvement and maladaptive coping responses.
C1 [Holt, Melissa K.; Reid, Gerald] Boston Univ, Sch Educ, Boston, MA 02215 USA.
[Matjasko, Jennifer L.] Ctr Dis Control & Prevent, Div Violence Prevent, Atlanta, GA USA.
[Espelage, Dorothy] Univ Illinois, Coll Educ, Champaign, IL USA.
[Koenig, Brian] K 12 Associates, Madison, WI USA.
RP Holt, MK (reprint author), Boston Univ, Sch Educ, 2 Silber Way, Boston, MA 02215 USA.
EM holtm@bu.edu
FU Dane County Youth Commission; Dane County Department of Human Services;
United Way of Dane County; Public Health Department of Madison and Dane
County; Dane County School Districts; American Educational Research
Association Meeting
FX Funding for this project was supported by Dane County Youth Commission,
the Dane County Department of Human Services, the United Way of Dane
County, the Public Health Department of Madison and Dane County, and the
participating Dane County School Districts. Dr Holt and Mr Reid received
travel funding through the School of Education at Boston University to
present findings from this study at the 2012 American Educational
Research Association Meeting.
NR 31
TC 3
Z9 4
U1 1
U2 12
PU AMER ACAD PEDIATRICS
PI ELK GROVE VILLAGE
PA 141 NORTH-WEST POINT BLVD,, ELK GROVE VILLAGE, IL 60007-1098 USA
SN 0031-4005
EI 1098-4275
J9 PEDIATRICS
JI Pediatrics
PD DEC
PY 2013
VL 132
IS 6
BP E1481
EP E1487
DI 10.1542/peds.2013-0401
PG 7
WC Pediatrics
SC Pediatrics
GA 282IG
UT WOS:000329163900003
PM 24218467
ER
PT J
AU Johnson, MG
Bradley, KK
Mendus, S
Burnsed, L
Clinton, R
Tiwari, T
AF Johnson, Matthew G.
Bradley, Kristy K.
Mendus, Susan
Burnsed, Laurence
Clinton, Rachel
Tiwari, Tejpratap
TI Vaccine-Preventable Disease Among Homeschooled Children: Two Cases of
Tetanus in Oklahoma
SO PEDIATRICS
LA English
DT Article
DE Oklahoma; prevention and control; schools; tetanus; vaccines
ID UNITED-STATES
AB Homeschooled children represent an increasing proportion of school-aged children in the United States. Immunization rates among homeschooled children are largely unknown because they are usually not subject to state-based school-entry vaccination requirements. Geographic foci of underimmunized children can increase the risk for outbreaks of vaccine-preventable diseases. In 2012, 2 cases of tetanus were reported in Oklahoma; both cases involved homeschooled children without documentation of diphtheria-tetanus-acellular pertussis vaccination. We describe the characteristics of both patients and outline innovative outreach measures with the potential to increase vaccination access and coverage among homeschooled children.
C1 [Johnson, Matthew G.] Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA USA.
[Tiwari, Tejpratap] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Bradley, Kristy K.] Oklahoma Dept Hlth, Off State Epidemiologist, Oklahoma City, OK 73117 USA.
[Mendus, Susan] Oklahoma Dept Hlth, Immunizat Serv, Oklahoma City, OK 73117 USA.
[Burnsed, Laurence; Clinton, Rachel] Oklahoma Dept Hlth, Acute Dis Serv, Oklahoma City, OK 73117 USA.
RP Johnson, MG (reprint author), Oklahoma Dept Hlth, Acute Dis Serv, 1000 NE 10th St, Oklahoma City, OK 73117 USA.
EM vil0@cdc.gov
NR 10
TC 1
Z9 1
U1 0
U2 0
PU AMER ACAD PEDIATRICS
PI ELK GROVE VILLAGE
PA 141 NORTH-WEST POINT BLVD,, ELK GROVE VILLAGE, IL 60007-1098 USA
SN 0031-4005
EI 1098-4275
J9 PEDIATRICS
JI Pediatrics
PD DEC
PY 2013
VL 132
IS 6
BP E1686
EP E1689
DI 10.1542/peds.2013-1636
PG 4
WC Pediatrics
SC Pediatrics
GA 282IG
UT WOS:000329163900030
PM 24218463
ER
PT J
AU Louie, JK
Yang, S
Samuel, MC
Uyeki, TM
Schechter, R
AF Louie, Janice K.
Yang, Samuel
Samuel, Michael C.
Uyeki, Timothy M.
Schechter, Robert
TI Neuraminidase Inhibitors for Critically Ill Children With Influenza
SO PEDIATRICS
LA English
DT Article
DE influenza; neuraminidase inhibitor; antiviral; critically ill;
mortality; children; pediatric; pediatric ICU
ID OSELTAMIVIR TREATMENT; ANTIVIRAL TREATMENT; HOSPITALIZED-PATIENTS;
SEASONAL INFLUENZA; RISK-FACTORS; INFECTION; OUTCOMES; A(H1N1);
CALIFORNIA; IMPACT
AB OBJECTIVE: Timely treatment with neuraminidase inhibitor (NAI) drugs appears to improve survival in adults hospitalized with influenza. We analyzed California surveillance data to determine whether NAI treatment improves survival in critically ill children with influenza.
METHODS: We analyzed data abstracted from medical records to characterize the outcomes of patients aged 0 to 17 years hospitalized in ICUs with laboratory-confirmed influenza from April 3, 2009, through September 30, 2012.
RESULTS: Seven hundred eighty-four influenza cases aged <18 years hospitalized in ICUs had information on treatment. Ninety percent (532 of 591) of cases during the 2009 H1N1 pandemic (April 3, 2009-August 31, 2010) received NAI treatment compared with 63% (121 of 193) of cases in the postpandemic period (September 1, 2010-September 30, 2012; P < .0001). Of 653 cases NAI-treated, 38 (6%) died compared with 11 (8%) of 131 untreated cases (odds ratio = 0.67, 95% confidence interval: 0.34-1.36). In a multivariate model that included receipt of mechanical ventilation and other factors associated with disease severity, the estimated risk of death was reduced in NAI-treated cases (odds ratio 0.36, 95% confidence interval: 0.16-0.83). Treatment within 48 hours of illness onset was significantly associated with survival (P = .04). Cases with NAI treatment initiated earlier in illness were less likely to die.
CONCLUSIONS: Prompt treatment with NAIs may improve survival of children critically ill with influenza. Recent decreased frequency of NAI treatment of influenza may be placing untreated critically ill children at an increased risk of death.
C1 [Louie, Janice K.; Yang, Samuel; Samuel, Michael C.; Schechter, Robert] Calif Dept Publ Hlth, Richmond, CA 94804 USA.
[Uyeki, Timothy M.] Ctr Dis Control & Prevent, Atlanta, GA USA.
RP Louie, JK (reprint author), Calif Dept Publ Hlth, 850 Marina Bay Pkwy, Richmond, CA 94804 USA.
EM Janice.louie@cdph.ca.gov
FU California Department of Public Health
FX All phases of this study were supported by the California Department of
Public Health. No external funding was secured for this study.
NR 30
TC 19
Z9 20
U1 0
U2 6
PU AMER ACAD PEDIATRICS
PI ELK GROVE VILLAGE
PA 141 NORTH-WEST POINT BLVD,, ELK GROVE VILLAGE, IL 60007-1098 USA
SN 0031-4005
EI 1098-4275
J9 PEDIATRICS
JI Pediatrics
PD DEC
PY 2013
VL 132
IS 6
BP E1539
EP E1545
DI 10.1542/peds.2013-2149
PG 7
WC Pediatrics
SC Pediatrics
GA 282IG
UT WOS:000329163900010
PM 24276847
ER
PT J
AU Biggs, HM
Hertz, JT
Munishi, OM
Galloway, RL
Marks, F
Saganda, W
Maro, VP
Crump, JA
AF Biggs, Holly M.
Hertz, Julian T.
Munishi, O. Michael
Galloway, Renee L.
Marks, Florian
Saganda, Wilbrod
Maro, Venance P.
Crump, John A.
TI Estimating Leptospirosis Incidence Using Hospital-Based Surveillance and
a Population-Based Health Care Utilization Survey in Tanzania
SO PLOS NEGLECTED TROPICAL DISEASES
LA English
DT Article
ID NORTHERN TANZANIA; INVASIVE BACTERIAL; FUNGAL-INFECTIONS; TYPHOID-FEVER;
SALMONELLA; SEYCHELLES; CHILDREN; ILLNESS; BURDEN
AB Background The incidence of leptospirosis, a neglected zoonotic disease, is uncertain in Tanzania and much of sub-Saharan Africa, resulting in scarce data on which to prioritize resources for public health interventions and disease control. In this study, we estimate the incidence of leptospirosis in two districts in the Kilimanjaro Region of Tanzania.
Methodology/Principal Findings We conducted a population-based household health care utilization survey in two districts in the Kilimanjaro Region of Tanzania and identified leptospirosis cases at two hospital-based fever sentinel surveillance sites in the Kilimanjaro Region. We used multipliers derived from the health care utilization survey and case numbers from hospital-based surveillance to calculate the incidence of leptospirosis. A total of 810 households were enrolled in the health care utilization survey and multipliers were derived based on responses to questions about health care seeking in the event of febrile illness. Of patients enrolled in fever surveillance over a 1 year period and residing in the 2 districts, 42 (7.14%) of 588 met the case definition for confirmed or probable leptospirosis. After applying multipliers to account for hospital selection, test sensitivity, and study enrollment, we estimated the overall incidence of leptospirosis ranges from 75-102 cases per 100,000 persons annually.
Conclusions/Significance We calculated a high incidence of leptospirosis in two districts in the Kilimanjaro Region of Tanzania, where leptospirosis incidence was previously unknown. Multiplier methods, such as used in this study, may be a feasible method of improving availability of incidence estimates for neglected diseases, such as leptospirosis, in resource constrained settings.
Author Summary Leptospirosis is a zoonotic infection that occurs worldwide and is caused by a spirochete, Leptospira spp. The incidence of leptospirosis is unknown in most of sub-Saharan Africa, including Tanzania. Incidence estimates are important in prioritizing resources for disease prevention and control. In this study, we calculated leptospirosis incidence in 2 districts in the Kilimanjaro Region of Tanzania using a multiplier method. We used responses from a population-based survey that asked where participants and their household members would seek health care in the event of fever along with the number of leptospirosis cases found at 2 hospitals under surveillance to calculate estimated incidence. We calculated a high incidence of leptospirosis in the study area that was previously unrecognized. This has important implications for prioritizing further research and consideration of public health control measures for leptospirosis in Tanzania.
C1 [Biggs, Holly M.; Hertz, Julian T.; Crump, John A.] Duke Univ, Med Ctr, Dept Med, Div Infect Dis, Durham, NC 27710 USA.
[Munishi, O. Michael; Maro, Venance P.; Crump, John A.] Kilimanjaro Christian Med Ctr, Moshi, Tanzania.
[Galloway, Renee L.] Ctr Dis Control & Prevent, Bacterial Special Pathogens Branch, Atlanta, GA USA.
[Marks, Florian] Int Vaccine Inst, Seoul, South Korea.
[Saganda, Wilbrod] Mawenzi Reg Hosp, Moshi, Tanzania.
[Maro, Venance P.; Crump, John A.] Kilimanjaro Christian Med Univ Coll, Moshi, Tanzania.
[Crump, John A.] Duke Univ, Duke Global Hlth Inst, Durham, NC USA.
RP Biggs, HM (reprint author), Duke Univ, Med Ctr, Dept Med, Div Infect Dis, Durham, NC 27710 USA.
EM john.crump@duke.edu
FU International Studies on AIDS Associated Co-infections (ISAAC) award, a
United States National Institutes of Health (NIH) [U01 AI062563];
Typhoid Fever Surveillance in sub-Saharan Africa Program (TSAP) grant
[OPPGH5231]; US National Institutes of Health grant as part of the joint
NIH-NSF Ecology of Infectious Disease program [R01TW009237]; UK Economic
and Social Research Council; Biotechnology and Biological Sciences
Research Council; NIH [2P30 AI064518]; NIH Fogarty International Center
AIDS International Training and Research Program [D43 PA-03-018]; Duke
Clinical Trials Unit and Clinical Research Sites [U01 AI069484];
[NIAID-AI007392]
FX This research was supported by an International Studies on AIDS
Associated Co-infections (ISAAC) award, a United States National
Institutes of Health (NIH) funded program (U01 AI062563). This work was
funded in part by the Typhoid Fever Surveillance in sub-Saharan Africa
Program (TSAP) grant OPPGH5231 and US National Institutes of Health
grant R01TW009237 as part of the joint NIH-NSF Ecology of Infectious
Disease program and the UK Economic and Social Research Council and
Biotechnology and Biological Sciences Research Council. This publication
was made possible with help from the Duke University Center for AIDS
Research (CFAR), an NIH funded program (2P30 AI064518). Authors received
support from the NIH Fogarty International Center AIDS International
Training and Research Program D43 PA-03-018 (VPM, JAC), NIAID-AI007392
(HMB), and the Duke Clinical Trials Unit and Clinical Research Sites U01
AI069484 (JAC, VPM). The funders had no role in study design, data
collection and analysis, decision to publish, or preparation of the
manuscript.
NR 32
TC 8
Z9 8
U1 0
U2 8
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1935-2735
J9 PLOS NEGLECT TROP D
JI Plos Neglect. Trop. Dis.
PD DEC
PY 2013
VL 7
IS 12
AR e2589
DI 10.1371/journal.pntd.0002589
PG 8
WC Infectious Diseases; Parasitology; Tropical Medicine
SC Infectious Diseases; Parasitology; Tropical Medicine
GA 282JU
UT WOS:000329168100006
PM 24340122
ER
PT J
AU Chu, BK
Deming, M
Biritwum, NK
Bougma, WR
Dorkenoo, AM
El-Setouhy, M
Fischer, PU
Gass, K
de Pena, M
Mercado-Hernandez, L
Kyelem, D
Lammie, PJ
Flueckiger, RM
Mwingira, UJ
Noordin, R
Owusu, IO
Ottesen, EA
Pavluck, A
Pilotte, N
Rao, RU
Samarasekera, D
Schmaedick, MA
Settinayake, S
Simonsen, PE
Supali, T
Taleo, F
Torres, M
Weil, GJ
Won, KY
AF Chu, Brian K.
Deming, Michael
Biritwum, Nana-Kwadwo
Bougma, Windtare R.
Dorkenoo, Ameyo M.
El-Setouhy, Maged
Fischer, Peter U.
Gass, Katherine
de Pena, Manuel Gonzalez
Mercado-Hernandez, Leda
Kyelem, Dominique
Lammie, Patrick J.
Flueckiger, Rebecca M.
Mwingira, Upendo J.
Noordin, Rahmah
Owusu, Irene Offei
Ottesen, Eric A.
Pavluck, Alexandre
Pilotte, Nils
Rao, Ramakrishna U.
Samarasekera, Dilhani
Schmaedick, Mark A.
Settinayake, Sunil
Simonsen, Paul E.
Supali, Taniawati
Taleo, Fasihah
Torres, Melissa
Weil, Gary J.
Won, Kimberly Y.
TI Transmission Assessment Surveys (TAS) to Define Endpoints for Lymphatic
Filariasis Mass Drug Administration: A Multicenter Evaluation
SO PLOS NEGLECTED TROPICAL DISEASES
LA English
DT Article
ID WUCHERERIA-BANCROFTI; GLOBAL PROGRAM; ELIMINATION; SURVEILLANCE; VECTOR;
TOOLS; HAITI
AB Background Lymphatic filariasis (LF) is targeted for global elimination through treatment of entire at-risk populations with repeated annual mass drug administration (MDA). Essential for program success is defining and confirming the appropriate endpoint for MDA when transmission is presumed to have reached a level low enough that it cannot be sustained even in the absence of drug intervention. Guidelines advanced by WHO call for a transmission assessment survey (TAS) to determine if MDA can be stopped within an LF evaluation unit (EU) after at least five effective rounds of annual treatment. To test the value and practicality of these guidelines, a multicenter operational research trial was undertaken in 11 countries covering various geographic and epidemiological settings.
Methodology The TAS was conducted twice in each EU with TAS-1 and TAS-2 approximately 24 months apart. Lot quality assurance sampling (LQAS) formed the basis of the TAS survey design but specific EU characteristics defined the survey site (school or community), eligible population (6-7 year olds or 1(st)-2(nd) graders), survey type (systematic or cluster-sampling), target sample size, and critical cutoff (a statistically powered threshold below which transmission is expected to be no longer sustainable). The primary diagnostic tools were the immunochromatographic (ICT) test for W. bancrofti EUs and the BmR1 test (Brugia Rapid or PanLF) for Brugia spp. EUs.
Principal Findings/Conclusions In 10 of 11 EUs, the number of TAS-1 positive cases was below the critical cutoff, indicating that MDA could be stopped. The same results were found in the follow-up TAS-2, therefore, confirming the previous decision outcome. Sample sizes were highly sex and age-representative and closely matched the target value after factoring in estimates of non-participation. The TAS was determined to be a practical and effective evaluation tool for stopping MDA although its validity for longer-term post-MDA surveillance requires further investigation.
Author Summary Lymphatic filariasis (LF) is targeted for global elimination through a strategy of repeated annual mass drug administration (MDA) to entire at-risk populations. A transmission assessment survey (TAS) is designed to evaluate whether transmission of LF is presumed to have reached a level low enough that it cannot be sustained in the absence of drug intervention and, therefore, MDA can be stopped. This multicenter operational research trial examines the value and practicality of the TAS guidelines through its implementation in 11 countries of diverse geographical and epidemiologic profiles. The field experiences support the TAS survey design methodology with particular respect to school and cluster-based sampling strategies. We found that sample sizes were age and sex representative and met the target values after factoring in estimates of non-participation rates. In 10 of 11 countries, the TAS found the number of positive cases in the evaluation unit to be no more than the statistically powered critical threshold. These results were corroborated in a follow-up TAS approximately 24 months later. We conclude the TAS is a valuable and effective tool for stopping MDA but its utility for longer-term post-MDA surveillance needs further empirical evidence and may be best supported with complementary tools and methods.
C1 [Chu, Brian K.; Gass, Katherine; Kyelem, Dominique; Flueckiger, Rebecca M.; Ottesen, Eric A.; Pavluck, Alexandre] Neglected Trop Dis Support Ctr, Task Force Global Hlth, Decatur, GA USA.
[Deming, Michael; Lammie, Patrick J.; Won, Kimberly Y.] Ctr Dis Control & Prevent, Div Parasit Dis & Malaria, Atlanta, GA USA.
[Biritwum, Nana-Kwadwo] Ghana Hlth Serv, Dept Publ Hlth, Accra, Ghana.
[Bougma, Windtare R.] Minist Sante, Programme Natl Eliminat Filariose Lymphat, Ouagadougou, Burkina Faso.
[Dorkenoo, Ameyo M.] Minist Sante, Programme Natl Eliminat Filariose Lymphat, Lome, Togo.
[El-Setouhy, Maged] Ain Shams Univ, Dept Community Environm & Occupat Med, Cairo, Egypt.
[Fischer, Peter U.; Weil, Gary J.] Washington Univ Sch Med, Div Infect Dis, St Louis, MO USA.
[de Pena, Manuel Gonzalez] Ctr Natl Control Enfermedades Trop, Santo Domingo, Dominican Rep.
[Mercado-Hernandez, Leda] Natl Ctr Dis Prevent & Control, Infect Dis Off, Manila, Philippines.
[Mwingira, Upendo J.] Natl Inst Med Res, Neglected Trop Dis Control Programme, Dar Es Salaam, Tanzania.
[Noordin, Rahmah] Univ Sains Malaysia, Inst Res Mol Med, George Town, Malaysia.
[Owusu, Irene Offei] Noguchi Mem Inst Med Res, Dept Epidemiol, Legon, Ghana.
[Pilotte, Nils; Torres, Melissa] Smith Coll, Dept Biol Sci, Northampton, MA 01063 USA.
[Rao, Ramakrishna U.] Washington Univ Sch Med, Dept Internal Med, St Louis, MO USA.
[Samarasekera, Dilhani; Settinayake, Sunil] Minist Hlth, Colombo, Sri Lanka.
[Schmaedick, Mark A.] Amer Samoa Community Coll, Div Community & Nat Resources, Pago Pago, AS USA.
[Simonsen, Paul E.] Univ Copenhagen, Fac Hlth & Med Sci, Copenhagen, Denmark.
[Supali, Taniawati] Univ Indonesia, Dept Parasitol, Jakarta, Indonesia.
[Taleo, Fasihah] Publ Hlth Directorate, Neglected Trop Dis Unit, Port Vila, Vanuatu.
RP Chu, BK (reprint author), Task Force Global Hlth, Neglected Trop Dis Support Ctr, Decatur, GA USA.
EM bchu@taskforce.org
RI Noordin, Rahmah/A-8277-2011
OI Noordin, Rahmah/0000-0001-7583-0752
FU Bill and Melinda Gates Foundation [OPP43922]
FX Funding for this study was provided by the Bill and Melinda Gates
Foundation, Grant #OPP43922. The funders had no role in study design,
data collection and analysis, decision to publish, or preparation of the
manuscript.
NR 26
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U1 1
U2 6
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1935-2735
J9 PLOS NEGLECT TROP D
JI Plos Neglect. Trop. Dis.
PD DEC
PY 2013
VL 7
IS 12
AR e2584
DI 10.1371/journal.pntd.0002584
PG 12
WC Infectious Diseases; Parasitology; Tropical Medicine
SC Infectious Diseases; Parasitology; Tropical Medicine
GA 282JU
UT WOS:000329168100010
PM 24340120
ER
PT J
AU Hester, J
Chan, ER
Menard, D
Mercereau-Puijalon, O
Barnwell, J
Zimmerman, PA
Serre, D
AF Hester, James
Chan, Ernest R.
Menard, Didier
Mercereau-Puijalon, Odile
Barnwell, John
Zimmerman, Peter A.
Serre, David
TI De Novo Assembly of a Field Isolate Genome Reveals Novel Plasmodium
vivax Erythrocyte Invasion Genes
SO PLOS NEGLECTED TROPICAL DISEASES
LA English
DT Article
ID HUMAN MALARIA PARASITE; DUFFY ANTIGEN; PROTEIN; FALCIPARUM; RECEPTOR;
REGION; SUPERFAMILY; POPULATION; DOMAIN; POLYMORPHISMS
AB Recent sequencing of Plasmodium vivax field isolates and monkey-adapted strains enabled characterization of SNPs throughout the genome. These analyses relied on mapping short reads onto the P. vivax reference genome that was generated using DNA from the monkey-adapted strain Salvador I. Any genomic locus deleted in this strain would be lacking in the reference genome sequence and missed in previous analyses. Here, we report de novo assembly of a P. vivax field isolate genome. Out of 2,857 assembled contigs, we identify 362 contigs, each containing more than 5 kb of contiguous DNA sequences absent from the reference genome sequence. These novel P. vivax DNA sequences account for 3.8 million nucleotides and contain 792 predicted genes. Most of these contigs contain members of multigene families and likely originate from telomeric regions. Interestingly, we identify two contigs containing predicted protein coding genes similar to known Plasmodium red blood cell invasion proteins. One gene encodes the reticulocyte-binding protein gene orthologous to P. cynomolgi RBP2e and P. knowlesi NBPXb. The second gene harbors all the hallmarks of a Plasmodium erythrocyte-binding protein, including conserved Duffy-binding like and C-terminus cysteine-rich domains. Phylogenetic analysis shows that this novel gene clusters separately from all known Plasmodium Duffy-binding protein genes. Additional analyses showing that this gene is present in most P. vivax genomes and transcribed in blood-stage parasites suggest that P. vivax red blood cell invasion mechanisms may be more complex than currently understood. The strategy employed here complements previous genomic analyses and takes full advantage of next-generation sequencing data to provide a comprehensive characterization of genetic variations in this important malaria parasite. Further analyses of the novel protein coding genes discovered through de novo assembly have the potential to identify genes that influence key aspects of P. vivax biology, including alternative mechanisms of human erythrocyte invasion.
Author SummaryPlasmodium vivax is responsible for most malaria cases outside Africa, but is poorly understood, as the parasite is difficult to study in vitro. Genome sequencing studies offer a novel and exciting opportunity to better understand this parasite but, so far, have directly mapped reads onto the reference genome sequence generated from a single P. vivax strain. Here, we use sequence data generated from a field isolate to reconstruct long DNA sequences without relying on the reference genome. Our analyses reveal many P. vivax DNA sequences that are absent from the reference genome and contain 792 predicted genes. One of these novel genes encodes a predicted protein similar to known Plasmodium proteins involved in red blood cell invasion. This new gene is present in all P. vivax strains sequenced so far, except for the strain used to generate the reference genome, and is transcribed in blood-stage parasites. Overall, our analyses show that the catalogue of P. vivax genes was incomplete and that potentially important genes have been missed. We notably identified one putative invasion gene that seems functional and could dramatically change our understanding of the mechanisms determining red blood cell invasion by this important malaria parasite.
C1 [Hester, James; Chan, Ernest R.; Serre, David] Cleveland Clin, Lerner Res Inst, Genom Med Inst, Cleveland, OH 44106 USA.
[Menard, Didier] Inst Pasteur Cambodge, Unite Epidemiol Mol, Phnom Penh, Cambodia.
[Mercereau-Puijalon, Odile] Inst Pasteur, Unite Immunol Mol Parasites, Paris, France.
[Barnwell, John] Ctr Dis Control & Prevent, Div Parasit Dis & Malaria, Atlanta, GA USA.
[Zimmerman, Peter A.] Case Western Reserve Univ, Ctr Global Hlth & Dis, Cleveland, OH 44106 USA.
RP Hester, J (reprint author), Cleveland Clin, Lerner Res Inst, Genom Med Inst, Cleveland, OH 44106 USA.
EM paz@case.edu; serred@ccf.org
OI Hester, James/0000-0002-2739-7082; Zimmerman, Peter/0000-0002-5349-4513
FU Cleveland CTSC Pilot award; NIAID award [R01 AI103228, R21 AI093922];
French Ministry of Foreign Affairs
FX This work was funded by a Cleveland CTSC Pilot award and a NIAID award
(R01 AI103228) to DS and a NIAID award (R21 AI093922) to PAZ. DM was
supported by the French Ministry of Foreign Affairs during this work.
The funders had no role in study design, data collection and analysis,
decision to publish, or preparation of the manuscript.
NR 45
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U1 0
U2 3
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1935-2735
J9 PLOS NEGLECT TROP D
JI Plos Neglect. Trop. Dis.
PD DEC
PY 2013
VL 7
IS 12
AR e2569
DI 10.1371/journal.pntd.0002569
PG 11
WC Infectious Diseases; Parasitology; Tropical Medicine
SC Infectious Diseases; Parasitology; Tropical Medicine
GA 282JU
UT WOS:000329168100036
PM 24340114
ER
PT J
AU Ford, ES
AF Ford, Earl S.
TI Food Security and Cardiovascular Disease Risk Among Adults in the United
States: Findings From the National Health and Nutrition Examination
Survey, 2003-2008
SO PREVENTING CHRONIC DISEASE
LA English
DT Article
ID INSECURITY; OBESITY; ADOLESCENTS; STRATEGIES; SMOKING; HUNGER
AB Introduction
Little is known about the relationship between food security status and predicted 10-year cardiovascular disease risk. The objective of this study was to examine the associations between food security status and cardiovascular disease risk factors and predicted 10-year risk in a national sample of US adults.
Methods
A cross-sectional analysis using data from 10,455 adults aged 20 years or older from the National Health and Nutrition Examination Survey 2003-2008 was conducted. Four levels of food security status were defined by using 10 questions.
Results
Among all participants, 83.9% had full food security, 6.7% had marginal food security, 5.8% had low food security, and 3.6% had very low food security. After adjustment, mean hemoglobin A1c was 0.15% greater and mean concentration of C-reactive protein was 0.8 mg/L greater among participants with very low food security than among those with full food security. The adjusted mean concentration of cotinine among participants with very low food security was almost double that of participants with full food security (112.8 vs 62.0 ng/mL, P < .001). No significant associations between food security status and systolic blood pressure or concentrations of total cholesterol, high-density lipoprotein cholesterol, or non-high-density lipoprotein cholesterol were observed. Participants aged 30 to 59 years with very low food security were more likely to have a predicted 10-year cardiovascular disease risk greater than 20% than fully food secure participants (adjusted prevalence ratio, 2.38; 95% CI, 1.31-4.31).
Conclusion
Adults aged 30 to 59 years with very low food security showed evidence of increased predicted 10-year cardiovascular disease risk.
C1 Ctr Dis Control & Prevent, Div Populat Hlth, Atlanta, GA 30341 USA.
RP Ford, ES (reprint author), Ctr Dis Control & Prevent, Div Populat Hlth, 4770 Buford Hwy,MS F78, Atlanta, GA 30341 USA.
EM cford@cdc.gov
NR 30
TC 6
Z9 6
U1 2
U2 20
PU CENTERS DISEASE CONTROL
PI ATLANTA
PA 1600 CLIFTON RD, ATLANTA, GA 30333 USA
SN 1545-1151
J9 PREV CHRONIC DIS
JI Prev. Chronic Dis.
PD DEC
PY 2013
VL 10
AR UNSP 130244
DI 10.5888/pcd10.130244
PG 10
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 285ME
UT WOS:000329397300001
ER
PT J
AU Richter, PA
Bishop, EE
Wang, JT
Kaufmann, R
AF Richter, Patricia A.
Bishop, Ellen E.
Wang, Jiantong
Kaufmann, Rachel
TI Trends in Tobacco Smoke Exposure and Blood Lead Levels Among Youths and
Adults in the United States: The National Health and Nutrition
Examination Survey, 1999-2008
SO PREVENTING CHRONIC DISEASE
LA English
DT Article
ID US CHILDREN; POPULATION
AB Introduction
Tobacco smoke is a source of exposure to thousands of toxic chemicals including lead, a chemical of longstanding public health concern. We assessed trends in blood lead levels in youths and adults with cotinine-verified tobacco smoke exposure by using 10 years of data from the National Health and Nutrition Examination Survey.
Methods
Geometric mean levels of blood lead are presented for increasing levels of tobacco smoke exposure. Regression models for lead included age, race/ethnicity, poverty, survey year, sex, age of home, birth country, and, for adults, alcohol consumption. Lead levels were evaluated for smokers and nonsmokers on the basis of age of residence and occupation.
Results
Positive trend tests indicate that a linear relationship exists between smoke exposure and blood lead levels in youths and adults and that secondhand smoke exposure contributes to blood lead levels above the level caused by smoking.
Conclusion
Youths with secondhand smoke exposure had blood lead levels suggestive of the potential for adverse cognitive outcomes. Despite remediation efforts in housing and the environment and declining smoking rates and secondhand smoke exposure in the United States, tobacco smoke continues to be a substantial source of exposure to lead in vulnerable populations and the population in general.
C1 [Richter, Patricia A.] Ctr Dis Control & Prevent, Off Smoking & Hlth, Atlanta, GA 30341 USA.
[Bishop, Ellen E.; Wang, Jiantong] RTI Int, Atlanta, GA USA.
[Kaufmann, Rachel] Ctr Dis Control & Prevent, Atlanta, GA 30341 USA.
RP Richter, PA (reprint author), Ctr Dis Control & Prevent, Off Smoking & Hlth, Atlanta, GA 30341 USA.
EM patricia.richter@fda.hhs.gov
FU Centers for Disease Control and Prevention (CDC)
FX All research was supported by internal funds of the Centers for Disease
Control and Prevention (CDC). The information and views expressed are
those of the authors and do not necessarily represent the views of the
US Food and Drug Administration (FDA) or of the US government. Dr
Richter was employed by CDC when this study was designed and conducted.
She is now employed by the FDA.
NR 27
TC 8
Z9 8
U1 1
U2 4
PU CENTERS DISEASE CONTROL
PI ATLANTA
PA 1600 CLIFTON RD, ATLANTA, GA 30333 USA
SN 1545-1151
J9 PREV CHRONIC DIS
JI Prev. Chronic Dis.
PD DEC
PY 2013
VL 10
AR UNSP 130056
DI 10.5888/pcd10.130056
PG 9
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 285ME
UT WOS:000329397300012
ER
PT J
AU Spencer, LM
Schooley, MW
Anderson, LA
Kochtitzky, CS
DeGroff, AS
Devlin, HM
Mercer, SL
AF Spencer, Lorine M.
Schooley, Michael W.
Anderson, Lynda A.
Kochtitzky, Chris S.
DeGroff, Amy S.
Devlin, Heather M.
Mercer, Shawna L.
TI Seeking Best Practices: A Conceptual Framework for Planning and
Improving Evidence-Based Practices
SO PREVENTING CHRONIC DISEASE
LA English
DT Article
ID PUBLIC-HEALTH; PREVENTION; STRATEGIES; OBESITY
AB How can we encourage ongoing development, refinement, and evaluation of practices to identify and build an evidence base for best practices? On the basis of a review of the literature and expert input, we worked iteratively to create a framework with 2 interrelated components. The first public health impact consists of 5 elements: effectiveness, reach, feasibility, sustainability, and transferability. The second quality of evidence consists of 4 levels, ranging from weak to rigorous. At the intersection of public health impact and quality of evidence, a continuum of evidence-based practice emerges, representing the ongoing development of knowledge across 4 stages: emerging, promising, leading, and best. This conceptual framework brings together important aspects of impact and quality to provide a common lexicon and criteria for assessing and strengthening public health practice. We hope this work will invite and advance dialogue among public health practitioners and decision makers to build and strengthen a diverse evidence base for public health programs and strategies.
C1 [Spencer, Lorine M.] Ctr Dis Control & Prevent, Appl Syst Res & Evaluat Branch, Div Publ Hlth Performance Improvement, Off State Tribal Local & Terr Support, Atlanta, GA 30341 USA.
[Schooley, Michael W.; Kochtitzky, Chris S.; DeGroff, Amy S.; Devlin, Heather M.; Mercer, Shawna L.] Ctr Dis Control & Prevent, Atlanta, GA 30341 USA.
[Anderson, Lynda A.] Emory Univ, Atlanta, GA 30322 USA.
RP Spencer, LM (reprint author), Ctr Dis Control & Prevent, Appl Syst Res & Evaluat Branch, Div Publ Hlth Performance Improvement, Off State Tribal Local & Terr Support, 4770 Buford Hwy NE,Mailstop E70, Atlanta, GA 30341 USA.
EM akx4@cdc.gov
NR 24
TC 8
Z9 8
U1 0
U2 2
PU CENTERS DISEASE CONTROL
PI ATLANTA
PA 1600 CLIFTON RD, ATLANTA, GA 30333 USA
SN 1545-1151
J9 PREV CHRONIC DIS
JI Prev. Chronic Dis.
PD DEC
PY 2013
VL 10
AR UNSP 130186
DI 10.5888/pcd10.130186
PG 9
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 285ME
UT WOS:000329397300006
ER
PT J
AU Lessa, FC
AF Lessa, Fernanda C.
TI Community-associated Clostridium difficile infection: How real is it?
SO ANAEROBE
LA English
DT Article; Proceedings Paper
CT 11th Biennial Congress of the Anaerobe-Society-of-the-Americas
CY JUN 27-JUL 01, 2012
CL San Francisco, CA
SP Anaerobe Soc Amer
DE Community-associated; Clostridium difficile infection; Surveillance
ID RISK; METAANALYSIS; HOSPITALS; OUTBREAK; DISEASE; COUNTY; MEAT
AB Community-associated Clostridium difficile infection (CA-CDI) represents 32% of all CDI cases based on U.S. population-based data. The current epidemic strain, NAP1, is the most prevalent strain causing these infections. Although complications, recurrence and death are uncommon, one-fourth of the CA-CDI patients are hospitalized within 7 days after the diagnosis. Published by Elsevier Ltd.
C1 Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA.
RP Lessa, FC (reprint author), Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Natl Ctr Emerging & Zoonot Infect Dis, 1600 Clifton Rd NE,MS A-24, Atlanta, GA 30333 USA.
EM flessa@cdc.gov
NR 23
TC 19
Z9 19
U1 0
U2 2
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1075-9964
EI 1095-8274
J9 ANAEROBE
JI Anaerobe
PD DEC
PY 2013
VL 24
BP 121
EP 123
DI 10.1016/j.anaerobe.2013.01.006
PG 3
WC Microbiology
SC Microbiology
GA 278TJ
UT WOS:000328912400025
PM 23403280
ER
PT J
AU Schier, JG
Hunt, DR
Perala, A
McMartin, KE
Bartels, MJ
Lewis, LS
McGeehin, MA
Flanders, WD
AF Schier, J. G.
Hunt, D. R.
Perala, A.
McMartin, K. E.
Bartels, M. J.
Lewis, L. S.
McGeehin, M. A.
Flanders, W. D.
TI Characterizing concentrations of diethylene glycol and suspected
metabolites in human serum, urine, and cerebrospinal fluid samples from
the Panama DEG mass poisoning
SO CLINICAL TOXICOLOGY
LA English
DT Article
DE Kidney; CNS/psychological; Metabolic; diethylene glycol; diglycolic
acid; hydroxyethoxyacetic acid
ID NEPHROTOXIC METABOLITE; DIGLYCOLIC ACID; IDENTIFICATION; TOXICITY; RATS;
1,4-DIOXANE; ETHYLENE
AB Context. Diethylene glycol (DEG) mass poisoning is a persistent public health problem. Unfortunately, there are no human biological data on DEG and its suspected metabolites in poisoning. If present and associated with poisoning, the evidence for use of traditional therapies such as fomepizole and/or hemodialysis would be much stronger. Objective. To characterize DEG and its metabolites in stored serum, urine, and cerebrospinal fluid (CSF) specimens obtained from human DEG poisoning victims enrolled in a 2006 case-control study. Methods. In the 2006 study, biological samples from persons enrolled in a case-control study (42 cases with new-onset, unexplained AKI and 140 age-, sex-, and admission date-matched controls without AKI) were collected and shipped to the Centers for Disease Control and Prevention (CDC) in Atlanta for various analyses and were then frozen in storage. For this study, when sufficient volume of the original specimen remained, the following analytes were quantitatively measured in serum, urine, and CSF: DEG, 2-hydroxyethoxyacetic acid (HEAA), diglycolic acid, ethylene glycol, glycolic acid, and oxalic acid. Analytes were measured using low resolution GC/MS, descriptive statistics calculated and case results compared with controls when appropriate. Specimens were de-identified so previously collected demographic, exposure, and health data were not available. The Wilcoxon Rank Sum test (with exact p-values) and bivariable exact logistic regression were used in SAS v9.2 for data analysis. Results. The following samples were analyzed: serum, 20 case, and 20 controls; urine, 11 case and 22 controls; and CSF, 11 samples from 10 cases and no controls. Diglycolic acid was detected in all case serum samples (median, 40.7 mcg/mL; range, 22.6-75.2) and no controls, and in all case urine samples (median, 28.7 mcg/mL; range, 14-118.4) and only five (23%) controls (median, 999; exact p < 0.0001); and 3) urinary glycolic acid (OR = 0.057; 95% C I = 0.001-0.55). Two CSF sample results were excluded and two from the same case were averaged, yielding eight samples from eight cases. Diglycolic acid was detected in seven (88%) of case CSF samples (median, 2.03 mcg/mL; range, < LLQ, 7.47). Discussion. Significantly elevated HEAA (serum) and diglycolic acid (serum and urine) concentrations were identified among cases, which is consistent with animal data. Low urinary glycolic acid concentrations in cases may have been due to concurrent AKI. Although serum glycolic concentrations among cases may have initially increased, further metabolism to oxalic acid may have occurred thereby explaining the similar glycolic acid concentrations in cases and controls. The increased serum oxalic acid concentration results in cases versus controls are consistent with this hypothesis. Conclusion. Diglycolic acid is associated with human DEG poisoning and may be a biomarker for poisoning. These findings add to animal data suggesting a possible role for traditional antidotal therapies. The detection of HEAA and diglycolic acid in the CSF of cases suggests a possible association with signs and symptoms of DEG-associated neurotoxicity.
Further work characterizing the pathophysiology of DEG-associated neurotoxicity and the role of traditional toxic alcohol therapies such as fomepizole and hemodialysis is needed.
C1 [Schier, J. G.; Hunt, D. R.; Lewis, L. S.; McGeehin, M. A.; Flanders, W. D.] Ctr Dis Control & Prevent, Div Environm Hazards & Hlth Effects, Natl Ctr Environm Hlth, Atlanta, GA USA.
[Schier, J. G.] Emory Univ, Sch Med, Dept Emergency Med, Atlanta, GA USA.
[Perala, A.; Bartels, M. J.] Dow Chem Co USA, Atlanta, GA USA.
[McMartin, K. E.] LSU Hlth Sci Ctr Shreveport, Shreveport, LA USA.
RP Schier, JG (reprint author), CDC, NCEH, EHHE, HSB, MS F-60,4770 Buford Hwy, Chamblee, GA 30341 USA.
EM jschier@cdc.gov
FU Orphan Medical; Centers for Disease Control and Prevention
FX Dr. McMartin has received royalty payments for Antizol (R) (original
fomepizole brand) from Orphan Medical and its descendants because of a
licensing agreement with Mericon Investment Group.; Support for the
laboratory analysis portion done by Dow Chemical Company of this study
came from the Centers for Disease Control and Prevention.
NR 22
TC 11
Z9 11
U1 0
U2 19
PU INFORMA HEALTHCARE
PI NEW YORK
PA 52 VANDERBILT AVE, NEW YORK, NY 10017 USA
SN 1556-3650
EI 1556-9519
J9 CLIN TOXICOL
JI Clin. Toxicol.
PD DEC
PY 2013
VL 51
IS 10
BP 923
EP 929
DI 10.3109/15563650.2013.850504
PG 7
WC Toxicology
SC Toxicology
GA 280TD
UT WOS:000329052800003
PM 24266434
ER
PT J
AU Calfee, MW
Rose, LJ
Morse, S
Mattorano, D
Clayton, M
Touati, A
Griffin-Gatchalian, N
Slone, C
McSweeney, N
AF Calfee, M. Worth
Rose, Laura J.
Morse, Stephen
Mattorano, Dino
Clayton, Matt
Touati, Abderrahmane
Griffin-Gatchalian, Nicole
Slone, Christina
McSweeney, Neal
TI Comparative evaluation of vacuum-based surface sampling methods for
collection of Bacillus spores
SO JOURNAL OF MICROBIOLOGICAL METHODS
LA English
DT Article
DE Surface sampling; Anthrax; Bacillus anthracis; Bioterrorism agent;
Vacuum sampling
ID ANTHRACIS SPORES; NONPOROUS SURFACES; DECONTAMINATION; RECOVERY; STERNE;
ISSUES; SCALE; GAPS
AB In this study, four commonly-used sampling devices (vacuum socks, 37 mm 0.8 mu m mixed cellulose ester (MCE) filter cassettes, 37 mm 0.3 mu m polytetrafluoroethylene (PTFE) filter cassettes, and 3M (TM) forensic filters) were comparatively evaluated for their ability to recover surface-associated spores. Aerosolized spores (similar to 10(5) CPU cm(-2)) of a Bacillus anthracis surrogate were allowed to settle onto three material types (concrete, carpet, and upholstery). Ten replicate samples were collected using each vacuum method, from each material type. Stainless steel surfaces, inoculated simultaneously with test materials, were sampled with pre-moistened wipes. Wipe recoveries were utilized to normalize vacuum-based recoveries across trials. Recovery (CFU cm(-2)) and relative recovery (vacuum recovery/wipe recovery) were determined for each method and material type. Recoveries and relative recoveries ranged from 3.8 x 10(3) to 7.4 x 10(4) CFU cm(-2) and 0.035 to 1242, respectively. ANOVA results indicated that the 37 mm MCE method exhibited higher relative recoveries than the other methods when used for sampling concrete or upholstery. While the vacuum sock resulted in the highest relative recoveries on carpet, no statistically significant difference was detected. The results of this study may be used to guide selection of sampling approaches following biological contamination incidents. Published by Elsevier B.V.
C1 [Calfee, M. Worth] US EPA, Natl Homeland Secur Res Ctr, Res Triangle Pk, NC 27711 USA.
[Rose, Laura J.; Morse, Stephen] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Mattorano, Dino] US EPA, Off Emergency Management, Cincinnati, OH 45268 USA.
[Clayton, Matt; Touati, Abderrahmane; Griffin-Gatchalian, Nicole; McSweeney, Neal] ARCADIS Geraghty & Miller Inc, Durham, NC USA.
[Slone, Christina] Kultech Inc, Cary, NC USA.
RP Calfee, MW (reprint author), US EPA, MD E343-06,109 TW Alexander Dr, Res Triangle Pk, NC 27711 USA.
EM calfee.worth@epa.gov
OI Calfee, Michael/0000-0001-6544-329X
FU CDC [RW-75-92345701]; US EPA [RW-75-92345701]
FX The U.S. Environmental Protection Agency through its Office of Research
and Development directed the research described herein under EP-C-09-027
with ARCADIS, Inc. This study was funded through an interagency
agreement between the CDC and the US EPA (RW-75-92345701). The authors
gratefully acknowledge the critical reviews by Sanjiv Shah (EPA) and
Matthew Arduino (CDC). This manuscript has been subject to an
administrative review but the findings and conclusions in this article
are of the authors, and do not necessarily reflect the views of the EPA
or CDC. No official endorsement should be inferred. The US EPA and CDC
do not endorse the purchase or sale of any commercial products or
services.
NR 31
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Z9 4
U1 0
U2 11
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0167-7012
EI 1872-8359
J9 J MICROBIOL METH
JI J. Microbiol. Methods
PD DEC
PY 2013
VL 95
IS 3
SI SI
BP 389
EP 396
DI 10.1016/j.mimet.2013.10.015
PG 8
WC Biochemical Research Methods; Microbiology
SC Biochemistry & Molecular Biology; Microbiology
GA 280BK
UT WOS:000329003500016
PM 24184017
ER
PT J
AU Barrera, R
Mackay, AJ
Amador, M
AF Barrera, Roberto
Mackay, Andrew J.
Amador, Manuel
TI AN IMPROVED TRAP TO CAPTURE ADULT CONTAINER-INHABITING MOSQUITOES
SO JOURNAL OF THE AMERICAN MOSQUITO CONTROL ASSOCIATION
LA English
DT Article
DE Aedes aegypti; Aedes mediovittatus; dengue; vector surveillance;
BG-Sentinel traps
ID AEDES-AEGYPTI DIPTERA; YELLOW-FEVER MOSQUITOS; BG-SENTINEL TRAP;
FAY-PRINCE TRAPS; PUERTO-RICO; CARBON-DIOXIDE; MEDIOVITTATUS DIPTERA;
FRENCH-POLYNESIA; DENGUE VIRUSES; AMERICAN-SAMOA
AB Although dengue viruses are thought to be transmitted by Aedes aegypti in Puerto Rico, Aedes mediovittatus, the Caribbean tree hole mosquito, is also a potential vector. This species is native to the Greater Antilles and has been shown to be a competent vector of dengue viruses in the laboratory. Consequently, it has been suggested that Ae. mediovittatus could be acting as a secondary vector or virus reservoir. This study was part of an ongoing investigation into this, and it aimed to determine whether BG-Sentinel traps (BGS traps) could be used to collect adults of this mosquito and could be modified to increase the number of captures of this species in the field. We conducted experiments to test the relative attractiveness of BGS traps to Ae. mediovittatus and Ae. aegypti and explored the effects of chemical lures (BG-Lure, CO2, octenol) and optical properties (color, size) on the capture rates of BGS traps in a large, outdoor cage in San Juan city, Puerto Rico. We also conducted field tests to compare modified BGS traps with the original traps in a rural community in Patillas municipality, Puerto Rico. Results obtained from the large, outdoor cage experiments indicated that trap captures of both mosquito species could be significantly enhanced by using black instead of white BGS traps combined with BG-Lure. Field experiments revealed that the modified traps captured a significantly greater number of Ae. aegypti, Ae. mediovittatus, and Culex quinquefasciatus, with greater sensitivity for the latter 2 species, and also captured a larger number of mosquito species and a smaller ratio of Ae. aegypti to Ae. mediovittatus, with greater than expected species co-occurrences.
C1 [Barrera, Roberto; Mackay, Andrew J.; Amador, Manuel] Ctr Dis Control & Prevent, Dengue Branch, San Juan, PR 00920 USA.
RP Barrera, R (reprint author), Ctr Dis Control & Prevent, Dengue Branch, Calle Canada, San Juan, PR 00920 USA.
RI Mashamba-Thompson, Tivani /B-6087-2014
FU Intramural CDC HHS [CC999999]
NR 47
TC 7
Z9 7
U1 2
U2 14
PU AMER MOSQUITO CONTROL ASSOC
PI MOUNT LAUREL
PA 15000 COMMERCE PARKWAY, SUITE C, MOUNT LAUREL, NJ 08054 USA
SN 8756-971X
EI 1943-6270
J9 J AM MOSQUITO CONTR
JI J. Am. Mosq. Control Assoc.
PD DEC
PY 2013
VL 29
IS 4
BP 358
EP 368
DI 10.2987/13-6343.1
PG 11
WC Entomology
SC Entomology
GA 278OK
UT WOS:000328899400006
PM 24551969
ER
PT J
AU Kothera, L
Nelms, BM
Reisen, WK
Savage, HM
AF Kothera, Linda
Nelms, Brittany M.
Reisen, William K.
Savage, Harry M.
TI Population Genetic and Admixture Analyses of Culex pipiens Complex
(Diptera: Culicidae) Populations in California, United States
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Article
ID WEST-NILE-VIRUS; NEW-YORK-CITY; BELOW-GROUND POPULATIONS; NORTH-AMERICA;
MICROSATELLITE LOCI; VECTOR COMPETENCE; FEEDING PATTERNS; MOSQUITOS;
PROGRAM; QUINQUEFASCIATUS
AB Microsatellite markers were used to genetically characterize 19 Culex pipiens complex populations from California. Two populations showed characteristics of earlier genetic bottlenecks. The overall F-ST value and a neighbor-joining tree suggested moderate amounts of genetic differentiation. Analyses using Structure indicated K = 4 genetic clusters: Cx. pipiens form pipiens L., Cx. quinquefasciatus Say, Cx. pipiens form molestus Forskal, and a group of genetically similar individuals of hybrid origin. A Discriminant Analysis of Principal Components indicated that the latter group is a mixture of the other three taxa, with form pipiens and form molestus contributing somewhat more ancestry than Cx. quinquefasciatus. Characterization of 56 morphologically autogenous individuals classified most as Cx. pipiens form molestus, and none as Cx. pipiens form pipiens or Cx. quinquefasciatus. Comparison of California microsatellite data with those of Cx. pipiens pallens Coquillett from Japan indicated the latter does not contribute significantly to genotypes in California.
C1 [Kothera, Linda; Savage, Harry M.] Ctr Dis Control & Prevent, Div Vector Borne Dis, Ft Collins, CO 80521 USA.
[Nelms, Brittany M.; Reisen, William K.] Univ Calif Davis, Sch Vet Med, Ctr Vectorborne Dis, Davis, CA 95616 USA.
RP Kothera, L (reprint author), Ctr Dis Control & Prevent, Div Vector Borne Dis, Ft Collins, CO 80521 USA.
EM lkothera@cdc.gov; bnelms@wesphotos.com; wkreisen@ucdavis.edu;
hms1@cdc.gov
FU Sacramento-Yolo MVCD; National Institutes of Allergy and Infectious
Diseases, National Institutes of Health (NIH) [RO1 AI55607]; NIH
fellowship from the Training Program in Biology of Disease Vectors
[T32-AI074550]; Research and Policy for Infectious Disease Dynamics
Program of the Science and Technology Directorate, Department of
Homeland Security; Fogarty International Center, NIH; Centers for
Disease Control and Prevention in Fort Collins, Colorado
FX This study was supported in part by a research grant from the
Sacramento-Yolo MVCD and grant RO1 AI55607 from the National Institutes
of Allergy and Infectious Diseases, National Institutes of Health (NIH).
Brittany M. Nelms was supported in part by an NIH fellowship from the
Training Program in Biology of Disease Vectors, grant number
T32-AI074550. William K. Reisen was supported by the Research and Policy
for Infectious Disease Dynamics Program of the Science and Technology
Directorate, Department of Homeland Security and the Fogarty
International Center, NIH. Linda Kothera and Harry M. Savage are
supported by the Centers for Disease Control and Prevention in Fort
Collins, Colorado.
NR 56
TC 8
Z9 8
U1 0
U2 10
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
EI 1476-1645
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2013
VL 89
IS 6
BP 1154
EP 1167
DI 10.4269/ajtmh.13-0040
PG 14
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 276CQ
UT WOS:000328726100017
PM 23958909
ER
PT J
AU Nelms, BM
Kothera, L
Thiemann, T
Macedo, PA
Savage, HM
Reisen, WK
AF Nelms, Brittany M.
Kothera, Linda
Thiemann, Tara
Macedo, Paula A.
Savage, Harry M.
Reisen, William K.
TI Phenotypic Variation among Culex pipiens Complex (Diptera: Culicidae)
Populations from the Sacramento Valley, California: Horizontal and
Vertical Transmission of West Nile Virus, Diapause Potential, Autogeny,
and Host Selection
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Article
ID NORTHEASTERN UNITED-STATES; MOLESTUS FORSKAL DIPTERA; NEW-YORK-CITY;
VECTOR COMPETENCE; QUINQUEFASCIATUS DIPTERA; NATURAL-POPULATIONS;
SOUTHERN CALIFORNIA; OVARIAN DEVELOPMENT; FEEDING PATTERNS; TARSALIS
DIPTERA
AB The vector competence and bionomics of Culex pipiens form pipiens L. and Cx. pipiens f. molestus Forskal were evaluated for populations from the Sacramento Valley. Both f. pipiens and f. molestus females became infected, produced disseminated infections, and were able to transmit West Nile virus. Form molestus females also transmitted West Nile virus vertically to egg rafts and F, progeny, whereas f. pipiens females only transmitted to egg rafts. Culex pipiens complex from urban Sacramento blood-fed on seven different avian species and two mammalian species. Structure analysis of blood-fed mosquitoes identified K = 4 genetic clusters: f. molestus, f. pipiens, a group of genetically similar hybrids (Cluster X), and admixed individuals. When females were exposed as larvae to midwinter conditions in bioenvironmental chambers, 85% (N = 79) of aboveground Cx. pipiens complex females and 100% (N = 34) of underground f. molestus females did not enter reproductive diapause.
C1 [Nelms, Brittany M.; Reisen, William K.] Univ Calif Davis, Sch Vet Med, Ctr Vectorborne Dis, Davis, CA 95616 USA.
[Kothera, Linda; Savage, Harry M.] Ctr Dis Control & Prevent, Div Vector Borne Dis, Ft Collins, CO USA.
[Thiemann, Tara] Univ Pacific, Dept Biol Sci, Stockton, CA 95211 USA.
[Macedo, Paula A.] SacramentoYolo Mosquito & Vector Control Dist, Elk Grove, CA USA.
RP Reisen, WK (reprint author), Univ Calif Davis, Sch Vet Med, Ctr Vectorborne Dis, Davis, CA 95616 USA.
EM bmmills@ucdavis.edu; lkothera@cdc.gov; tthiemann@pacific.edu;
pmacedo@sac-yolomvcd.com; hmsl@cdc.gov; wkreisen@ucdavis.edu
FU NIH Research grant from the National Institute of Allergy and Infectious
Diseases, NIH [RO1 AI 55607]; Sacramento-Yolo MVCD; NIH fellowship from
the Training Program in Biology of Disease Vectors [T32AI074550];
Research and Policy for Infectious Disease Dynamics (RAPIDD) program of
the Science and Technology Directorate, Department of Homeland Security;
Fogarty International Center, National Institutes of Health
FX This research was supported by NIH Research grant RO1 AI 55607 from the
National Institute of Allergy and Infectious Diseases, NIH, funds
provided by the Sacramento-Yolo MVCD and an NIH fellowship from the
Training Program in Biology of Disease Vectors, grant no. T32AI074550.
W. K. Reisen acknowledges support from the Research and Policy for
Infectious Disease Dynamics (RAPIDD) program of the Science and
Technology Directorate, Department of Homeland Security and Fogarty
International Center, National Institutes of Health.
NR 85
TC 7
Z9 8
U1 0
U2 19
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
EI 1476-1645
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2013
VL 89
IS 6
BP 1168
EP 1178
DI 10.4269/ajtmh.13-0219
PG 11
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 276CQ
UT WOS:000328726100018
PM 24043690
ER
PT J
AU Edupuganti, S
Mulligan, MJ
Eidex, RB
Cetron, M
Marfin, AA
AF Edupuganti, Srilatha
Mulligan, Mark J.
Eidex, Rachel B.
Cetron, Martin
Marfin, Anthony A.
TI 17D Yellow Fever Virus Vaccine Response
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Letter
ID ANTIBODIES; TRIAL
C1 [Edupuganti, Srilatha; Mulligan, Mark J.] Emory Univ, Sch Med, Atlanta, GA 30332 USA.
[Eidex, Rachel B.; Cetron, Martin; Marfin, Anthony A.] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA.
RP Edupuganti, S (reprint author), Emory Univ, Sch Med, Atlanta, GA 30332 USA.
EM mark.mulligan@emory.edu
NR 12
TC 1
Z9 1
U1 0
U2 5
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
EI 1476-1645
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2013
VL 89
IS 6
BP 1226
EP 1227
DI 10.4269/ajtmh.13-0443b
PG 2
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 276CQ
UT WOS:000328726100030
PM 24306032
ER
PT J
AU Hodge, DR
Prentice, KW
Ramage, JG
Prezioso, S
Gauthier, C
Swanson, T
Hastings, R
Basavanna, U
Datta, S
Sharma, SK
Garber, EAE
Staab, A
Pettit, D
Drumgoole, R
Swaney, E
Estacio, PL
Elder, IA
Kovacs, G
Morse, BS
Kellogg, RB
Stanker, L
Morse, SA
Pillai, SP
AF Hodge, David R.
Prentice, Kristin Willner
Ramage, Jason G.
Prezioso, Samantha
Gauthier, Cheryl
Swanson, Tanya
Hastings, Rebecca
Basavanna, Uma
Datta, Shomik
Sharma, Shashi K.
Garber, Eric A. E.
Staab, Andrea
Pettit, Denise
Drumgoole, Rahsaan
Swaney, Erin
Estacio, Peter L.
Elder, Ian A.
Kovacs, Gerald
Morse, Brenda S.
Kellogg, Richard B.
Stanker, Larry
Morse, Stephen A.
Pillai, Segaran P.
TI COMPREHENSIVE LABORATORY EVALUATION OF A HIGHLY SPECIFIC LATERAL FLOW
ASSAY FOR THE PRESUMPTIVE IDENTIFICATION OF RICIN IN SUSPICIOUS WHITE
POWDERS AND ENVIRONMENTAL SAMPLES
SO BIOSECURITY AND BIOTERRORISM-BIODEFENSE STRATEGY PRACTICE AND SCIENCE
LA English
DT Article
ID RIBOSOME-INACTIVATING PROTEINS; COMMUNIS AGGLUTININ; CASTOR BEANS;
TOXINS; GENE; SEQUENCE; AGENTS; CHAIN; ELECTROCHEMILUMINESCENCE;
CYTOTOXICITY
AB Ricin, a heterodimeric toxin that is present in the seeds of the Ricinus communis plant, is the biothreat agent most frequently encountered by law enforcement agencies in the United States. Even in untrained hands, the easily obtainable seeds can yield a highly toxic product that has been used in various types of threats, including white-powder letters. Although the vast majority of these threats are hoaxes, an impediment to accurate hazard assessments by first responders is the unreliability of rapid detection assays for ricin, such as lateral flow assays (LFAs). One of the complicating factors associated with LFAs is the incorporation of antibodies of poor specificity that cross-react with near-neighbors or with plant lectins that are capable of nonspecifically cross-linking the capture and detector antibodies. Because of the compelling and critical need to promote the interests of public safety and public health, the Department of Homeland Security conducted a comprehensive laboratory evaluation study of a commercial LFA for the rapid detection of ricin. This study was conducted using comprehensive inclusivity and exclusivity panels of ricin and near-neighbor plant materials, along with panels of lectins and white-powders, to determine the specificity, sensitivity, limits of detection, dynamic range, and repeatability of the assay for the specific intended use of evaluating suspicious white powders and environmental samples in the field.
C1 [Hodge, David R.; Prentice, Kristin Willner] Booz Allen & Hamilton Inc, Mclean, VA 22102 USA.
[Ramage, Jason G.; Pillai, Segaran P.] US Dept Homeland Secur, Sci & Technol Directorate, Chem & Biol Def Div, Washington, DC USA.
[Prezioso, Samantha] Ctr Dis Control & Prevent, Natl Ctr Emerging & Zoonot Infect Dis, Div Foodborne Waterborne & Environm Dis, Atlanta, GA USA.
[Gauthier, Cheryl; Swanson, Tanya; Hastings, Rebecca] Massachusetts Dept Publ Hlth, Bioterrorism Response Lab, State Lab Inst, Jamaica Plain, MA USA.
[Basavanna, Uma] USAMRIID, Ft Detrick, MD USA.
[Datta, Shomik; Sharma, Shashi K.; Garber, Eric A. E.] Food & Drug Adm, Ctr Food Safety & Appl Nutr, Off Regulatory Sci, College Pk, MD USA.
[Pettit, Denise] NC Dept Hlth & Human Serv, North Carolina State Lab Publ Hlth, Raleigh, NC USA.
[Drumgoole, Rahsaan; Swaney, Erin] Texas Dept State Hlth Serv, Emergency Preparedness Branch, Austin, TX USA.
[Estacio, Peter L.] Lawrence Livermore Natl Lab, Environm Hlth & Qual Assurance, Livermore, CA USA.
[Elder, Ian A.] US Dept Homeland Secur, Washington, DC USA.
[Morse, Brenda S.; Kellogg, Richard B.] CDC, Natl Ctr Emerging & Zoonot Infect Dis, Div Preparedness & Emerging Infect, Lab Preparedness & Response Branch, Atlanta, GA 30333 USA.
[Stanker, Larry] USDA ARS, Foodborne Toxin Detect & Prevent Res Unit, Albany, CA USA.
[Morse, Stephen A.] CDC, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA.
RP Hodge, DR (reprint author), Dept Homeland Secur, S&T BOD STOP 0201,245 Murray Lane, Washington, DC 20528 USA.
EM David.Hodge@hq.dhs.gov
NR 52
TC 13
Z9 13
U1 1
U2 12
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1538-7135
EI 1557-850X
J9 BIOSECUR BIOTERROR
JI Biosecur. Bioterror.
PD DEC 1
PY 2013
VL 11
IS 4
BP 237
EP 250
DI 10.1089/bsp.2013.0053
PG 14
WC Public, Environmental & Occupational Health; International Relations
SC Public, Environmental & Occupational Health; International Relations
GA 276KT
UT WOS:000328749900003
PM 24320219
ER
PT J
AU Sobelson, RK
Young, AC
Marcus, LJ
Dorn, BC
Neslund, VS
McNulty, EJ
AF Sobelson, Robyn K.
Young, Andrea C.
Marcus, Leonard J.
Dorn, Barry C.
Neslund, Verla S.
McNulty, Eric J.
TI THE META-LEADERSHIP SUMMIT FOR PREPAREDNESS INITIATIVE: AN INNOVATIVE
MODEL TO ADVANCE PUBLIC HEALTH PREPAREDNESS AND RESPONSE
SO BIOSECURITY AND BIOTERRORISM-BIODEFENSE STRATEGY PRACTICE AND SCIENCE
LA English
DT Article
ID EMERGENCY MANAGEMENT; TOOL
AB This article reports on the design, evaluation framework, and results from the Meta-Leadership Summit for Preparedness Initiative. The Meta-Leadership Summit for Preparedness was a 5-year initiative based on the premise that national preparedness and emergency response is not solely the responsibility of government. From 2006 to 2011, 36 Meta-Leadership Summits were delivered in communities across the country. Summits were customized, 10-hour leadership development, networking, and community action planning events. They included participation from targeted federal, state, local, nonprofit/philanthropic, and private sector leaders who are directly involved in decision making during a major community or state-wide emergency. A total of 4,971 government, nonprofit, and business leaders attended Meta-Leadership Summits; distribution of attendees by sector was balanced. Ninety-three percent of respondents reported the summit was a valuable use of time, 91% reported the overall quality as good or outstanding, and 91% would recommend the summit to their colleagues. In addition, approximately 6 months after attending a summit, 80% of respondents reported that they had used meta-leadership concepts or principles. Of these, 93% reported that using meta-leadership concepts or principles had made a positive difference for them and their organizations. The Meta-Leadership Summit for Preparedness Initiative was a value-added opportunity for communities, providing the venue for learning the concepts and practice of meta-leadership, multisector collaboration, and resource sharing with the intent of substantively improving preparedness, response, and recovery efforts.
C1 [Sobelson, Robyn K.] Ctr Dis Control & Prevent, Off Publ Hlth Preparedness & Response, Atlanta, GA 30329 USA.
[Young, Andrea C.] Ctr Dis Control & Prevent, Off State Tribal Local & Terr Support, Atlanta, GA 30329 USA.
[Marcus, Leonard J.] Harvard Univ, Sch Publ Hlth, Natl Preparedness Leadership Initiat, Cambridge, MA 02138 USA.
[McNulty, Eric J.] Harvard Univ, Sch Publ Hlth, NPLI, Res Program, Cambridge, MA 02138 USA.
[McNulty, Eric J.] Harvard Univ, Sch Publ Hlth, NPLI, Profess Program, Cambridge, MA 02138 USA.
[Dorn, Barry C.] Harvard Univ, Sch Publ Hlth, Cambridge, MA 02138 USA.
[Neslund, Verla S.] CDC Fdn, Atlanta, GA USA.
RP Sobelson, RK (reprint author), Ctr Dis Control & Prevent, Learning Off, Off Publ Hlth Preparedness & Response, 1600 Clifton Rd,NE,MS D-44, Atlanta, GA 30329 USA.
EM rsobelson@cdc.gov
NR 24
TC 1
Z9 1
U1 0
U2 10
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1538-7135
EI 1557-850X
J9 BIOSECUR BIOTERROR
JI Biosecur. Bioterror.
PD DEC 1
PY 2013
VL 11
IS 4
BP 251
EP 261
DI 10.1089/bsp.2013.0056
PG 11
WC Public, Environmental & Occupational Health; International Relations
SC Public, Environmental & Occupational Health; International Relations
GA 276KT
UT WOS:000328749900004
PM 24251597
ER
PT J
AU Posid, JM
Bruce, SM
Guarnizo, JT
O'Connor, RC
Papagiotas, SS
Taylor, ML
AF Posid, Joseph M.
Bruce, Sherrie M.
Guarnizo, Julie T.
O'Connor, Ralph C., Jr.
Papagiotas, Stephen S.
Taylor, Melissa L.
TI PUBLIC HEALTH EMERGENCIES AND RESPONSES: WHAT ARE THEY, HOW LONG DO THEY
LAST, AND HOW MANY STAFF DOES YOUR AGENCY NEED?
SO BIOSECURITY AND BIOTERRORISM-BIODEFENSE STRATEGY PRACTICE AND SCIENCE
LA English
DT Article
ID FUTURE; SARS
AB Responding to outbreaks is one of the most routine yet most important functions of a public health agency. However, some outbreaks are bigger, more visible, or more complex than others, prompting discussion about when an outbreak becomes a public health emergency. When a public health emergency is identified, resources (eg, funding, staff, space) may need to be redirected from core public health programs to contribute to the public health emergency response. The need to sustain critical public health functions while preparing for public health emergency responses raises a series of operational and resource management questions, including when a public health emergency begins and ends, why additional resources are needed, how long an organization should expect staff to be redirected, and how many staff (or what proportion of the agency's staff) an organization should anticipate will be needed to conduct a public health emergency response. This article addresses these questions from a national perspective by reviewing events for which the Centers for Disease Control and Prevention redirected staff from core public health functions to respond to a series of public health emergencies. We defined public health emergency in both operational and public health terms and found that on average each emergency response lasted approximately 4 months and used approximately 9.5% of our workforce. We also provide reasons why public health agencies should consider the impact of redirecting resources when preparing for public health emergencies.
C1 [Posid, Joseph M.; Bruce, Sherrie M.; Guarnizo, Julie T.; Papagiotas, Stephen S.; Taylor, Melissa L.] Ctr Dis Control & Prevent, Natl Ctr Emerging & Zoonot Infect Dis, Div Preparedness & Emerging Infect, Atlanta, GA 30333 USA.
[O'Connor, Ralph C., Jr.] Ctr Dis Control & Prevent, Off Publ Hlth Preparedness & Response, Div Emergency Operat, Atlanta, GA 30333 USA.
RP Posid, JM (reprint author), Ctr Dis Control & Prevent, NCEZID DPEI, 1600 Clifton Rd,MS C-18, Atlanta, GA 30333 USA.
EM jmp2@cdc.gov
NR 14
TC 0
Z9 0
U1 1
U2 4
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1538-7135
EI 1557-850X
J9 BIOSECUR BIOTERROR
JI Biosecur. Bioterror.
PD DEC 1
PY 2013
VL 11
IS 4
BP 271
EP 279
DI 10.1089/bsp.2013.0044
PG 9
WC Public, Environmental & Occupational Health; International Relations
SC Public, Environmental & Occupational Health; International Relations
GA 276KT
UT WOS:000328749900006
PM 24219494
ER
PT J
AU Allen, JA
Longenecker, HB
Perrine, CG
Scanlon, KS
AF Allen, Jessica A.
Longenecker, Holly B.
Perrine, Cria G.
Scanlon, Kelley S.
TI Baby-Friendly Hospital Practices and Birth Costs
SO BIRTH-ISSUES IN PERINATAL CARE
LA English
DT Article
DE breastfeeding; maternity care practices; birth costs
ID UNITED-STATES
AB Background: Hospital practices supportive of breastfeeding can improve breastfeeding rates. There are limited data available on how improved hospital practices are associated with hospital costs. We describe the association between the number of breastfeeding supportive practices a hospital has in place and the cost of an uncomplicated birth.
Methods: Data from hospitals in 20 states that participated in the 2007 Maternity Practices in Infant Nutrition and Care (mPINC) survey and Healthcare Cost and Utilization Project's (HCUP) State Inpatient Databases (SID) were merged to calculate the average median hospital cost of uncomplicated vaginal and cesarean section births by number of ideal practices from the Ten Steps to Successful Breastfeeding. Linear regression analyses were conducted to estimate change in birth cost for each additional ideal practice in place.
Results: Sixty-one percent of hospitals had ideal practice on 3-5 of the 10 steps, whereas 29 percent of hospitals had ideal practice on 6-8. Adjusted analyses of uncomplicated births revealed a higher but nonsignificant increase in any of the birth categories (all births, $19; vaginal, $15; cesarean section, $39) with each additional breastfeeding supportive maternity care practice in place.
Conclusions: Our results revealed that the number of breastfeeding supportive practices a hospital has in place is not significantly associated with higher birth costs. Concern for higher birth costs should not be a barrier for improving maternity care practices that support women who choose to breastfeed. (BIRTH 40: 4 December 2013)
C1 [Allen, Jessica A.; Perrine, Cria G.; Scanlon, Kelley S.] Ctr Dis Control & Prevent, Div Nutr Phys Act & Obes, Atlanta, GA 30341 USA.
[Longenecker, Holly B.] Northrop Grumman Corp, Atlanta, GA USA.
RP Allen, JA (reprint author), Ctr Dis Control & Prevent, 4770 Buford Hwy NE,Mailstop F-77, Atlanta, GA 30341 USA.
FU Intramural CDC HHS [CC999999]; NIDDK NIH HHS [T32 DK007734]
NR 26
TC 1
Z9 1
U1 1
U2 6
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0730-7659
EI 1523-536X
J9 BIRTH-ISS PERINAT C
JI Birth-Issue Perinat. Care
PD DEC
PY 2013
VL 40
IS 4
BP 221
EP 226
DI 10.1111/birt.12062
PG 6
WC Nursing; Obstetrics & Gynecology; Pediatrics
SC Nursing; Obstetrics & Gynecology; Pediatrics
GA 274CK
UT WOS:000328582500004
PM 24344702
ER
PT J
AU Rainey, JJ
Sugerman, D
Brennan, M
Cadet, JR
Ernsly, J
Lacapere, F
Danovaro-Holliday, MC
Mubalama, JC
Nandy, R
AF Rainey, Jeanette J.
Sugerman, David
Brennan, Muireann
Cadet, Jean Ronald
Ernsly, Jackson
Lacapere, Francois
Danovaro-Holliday, M. Carolina
Mubalama, Jean-Claude
Nandy, Robin
TI Rapid monitoring in vaccination campaigns during emergencies: the
post-earthquake campaign in Haiti
SO BULLETIN OF THE WORLD HEALTH ORGANIZATION
LA English
DT Article
ID AMERICA
AB Problem The earthquake that struck Haiti in January 2010 caused 1.5 million people to be displaced to temporary camps. The Haitian Ministry of Public Health and Population and global immunization partners developed a plan to deliver vaccines to those residing in these camps. A strategy was needed to determine whether the immunization targets set for the campaign were achieved.
Approach Following the vaccination campaign, staff from the Ministry of Public Health and Population interviewed convenience samples of households in specific predetermined locations in each of the camps-regarding receipt of the emergency vaccinations. A camp was targeted for "mop-up vaccination" i.e. repeat mass vaccination if more than 25% of the children aged 9 months to 7 years in the sample were found not to have received the emergency vaccinations.
Local setting Rapid monitoring was implemented in camps located in the Port-au-Prince metropolitan area. Camps that housed more than 5000 people were monitored first.
Relevant changes By the end of March 2010, 72 (23%) of the 310 vaccinated camps had been monitored. Although 32 (44%) of the monitored camps were targeted for mop-up vaccination, only six of them had received such repeat mass vaccination when checked several weeks after monitoring.
Lessons learnt Rapid, monitoring was only marginally beneficial in achieving immunization targets in the temporary camps in Port-au-Prince. More research is needed to evaluate the utility of conventional rapid monitoring, as well as other strategies, during post-disaster vaccination campaigns that involve mobile populations, particularly when there is little capacity to conduct repeat mass vaccination.
C1 [Rainey, Jeanette J.; Sugerman, David] Ctr Dis Control & Prevent, Global Immunizat Div, Atlanta, GA 30333 USA.
[Brennan, Muireann] Ctr Dis Control & Prevent, Int Emergency & Refugee Hlth Branch, Atlanta, GA 30333 USA.
[Cadet, Jean Ronald] Minist Publ Hlth & Populat, Expanded Programme Immunizat, Port Au Prince, Haiti.
[Ernsly, Jackson; Mubalama, Jean-Claude] United Nations Childrens Fund, Hlth Sect, Port Au Prince, Haiti.
[Lacapere, Francois] Pan Amer Hlth Org, Expanded Programme Immunizat, Port Au Prince, Haiti.
[Danovaro-Holliday, M. Carolina] Pan Amer Hlth Org, Comprehens Family Immunizat, Washington, DC USA.
[Nandy, Robin] United Nations Childrens Fund, Hlth Sect, New York, NY USA.
RP Rainey, JJ (reprint author), Ctr Dis Control & Prevent, Global Immunizat Div, 1600 Clifton Rd,MS E-05, Atlanta, GA 30333 USA.
EM jkr7@cdc.gov
NR 10
TC 0
Z9 0
U1 0
U2 7
PU WORLD HEALTH ORGANIZATION
PI GENEVA 27
PA MARKETING AND DISSEMINATION, CH-1211 GENEVA 27, SWITZERLAND
SN 0042-9686
EI 1564-0604
J9 B WORLD HEALTH ORGAN
JI Bull. World Health Organ.
PD DEC
PY 2013
VL 91
IS 12
BP 957
EP 962
DI 10.2471/BLT.12.117044
PG 6
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 275XT
UT WOS:000328713400016
PM 24347735
ER
PT J
AU Bass, J
Tack, DM
McCollum, AM
Kabamba, J
Pakuta, E
Malekani, J
Nguete, B
Monroe, BP
Doty, JB
Karhemere, S
Damon, IK
Balilo, M
Okitolonda, E
Shongo, RL
Reynolds, MG
AF Bass, Jennifer
Tack, Danielle M.
McCollum, Andrea M.
Kabamba, Joelle
Pakuta, Elisabeth
Malekani, Jean
Nguete, Beatrice
Monroe, Benjamin P.
Doty, Jeffrey B.
Karhemere, Stomy
Damon, Inger K.
Balilo, Marcel
Okitolonda, Emile
Shongo, Robert L.
Reynolds, Mary G.
TI Enhancing health care worker ability to detect and care for patients
with monkeypox in the Democratic Republic of the Congo
SO INTERNATIONAL HEALTH
LA English
DT Article
DE Monkeypox; PCR; Surveillance; Training evaluation; Zoonosis
ID VIRUS; TRANSMISSION; SMALLPOX; SURVEILLANCE; OUTBREAK; FEATURES
AB Monkeypox (MPX) is an endemic disease of public health importance in the Democratic Republic of the Congo (DRC). In 2010, the DRC Ministry of Health joined with external partners to improve MPX surveillance in the Tshuapa Health District of DRC. A pivotal component of the program is training of health zone personnel in surveillance methods and patient care. In this report we evaluate outcomes of the training program.
Health care worker knowledge of key concepts in the MPX training curriculum was assessed using an anonymous self-administered survey. Additionally, evaluators collected feedback about the capacity of participants to perform the surveillance tasks. Training impacts were determined by assessing various surveillance performance metrics.
Correct trainee responses to questions about MPX symptoms and patient care increased significantly upon completion of training events. During the 12 months after the initial training, the proportion of suspected cases investigated increased significantly (from 6.7 to 37.3), as compared to the 5 months prior. However, the proportion of reported cases that were ultimately confirmed remained unchanged, 20.1 (5/24) vs 23.3 (60/257).
We have demonstrated that the MPX curriculum developed for this initiative was effective in transferring knowledge and was associated with improved detection of human MPX cases.
C1 [Bass, Jennifer; McCollum, Andrea M.; Monroe, Benjamin P.; Doty, Jeffrey B.; Damon, Inger K.; Reynolds, Mary G.] US Ctr Dis Control & Prevent, Poxvirus & Rabies Branch, Atlanta, GA 30333 USA.
[Tack, Danielle M.] US Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA USA.
[Kabamba, Joelle] US Ctr Dis Control & Prevent, Country Operat Branch, Kinshasa, Zaire.
[Pakuta, Elisabeth; Karhemere, Stomy] Minist Hlth, Natl Inst Biomed Res, Kinshasa, Zaire.
[Malekani, Jean] Univ Kinshasa, Dept Biol Sci, Kinshasa, Zaire.
[Okitolonda, Emile] Univ Kinshasa, Ctr HIV AIDS Strateg Informat, Kinshasa, Zaire.
[Balilo, Marcel; Shongo, Robert L.] Minist Hlth, Hemorrhag Fever & Monkeypox Program, Kinshasa, Zaire.
RP Reynolds, MG (reprint author), US Ctr Dis Control & Prevent, Poxvirus & Rabies Branch, Atlanta, GA 30333 USA.
EM nzr6@cdc.gov
FU US Centers for Disease Control and Prevention
FX This work was funded by the US Centers for Disease Control and
Prevention. The findings and conclusions in this report are those of the
author(s) and do not necessarily represent the views of the funding
agency.
NR 23
TC 1
Z9 1
U1 1
U2 3
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1876-3413
EI 1876-3405
J9 INT HEALTH
JI Int. Health
PD DEC
PY 2013
VL 5
IS 4
BP 237
EP 243
DI 10.1093/inthealth/iht029
PG 7
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 271BH
UT WOS:000328364800001
PM 24246742
ER
EF