FN Thomson Reuters Web of Science™ VR 1.0 PT J AU CHEN, JYJ TSENG, J KOMISAR, J HSU, IC AF CHEN, JYJ TSENG, J KOMISAR, J HSU, IC TI ENHANCED PRODUCTION OF STAPHYLOCOCCAL ENTEROTOXIN-B (SEB) WITH A SITE-SPECIFIC MUTATION IN THE DISULFIDE LOOP SO FASEB JOURNAL LA English DT Meeting Abstract C1 UNIV MARYLAND,SCH MED,DEPT PATHOL,BALTIMORE,MD 21201. WALTER REED ARMY INST RES,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A774 EP A774 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19701099 ER PT J AU CLAYBAUGH, JR SATO, AK UYEHARA, CFT AF CLAYBAUGH, JR SATO, AK UYEHARA, CFT TI EFFECTS OF VASOPRESSIN (VP) ON THE CARDIOPULMONARY RESPONSES TO HYPOXIA IN THE CONSCIOUS, SPONTANEOUSLY BREATHING, GOAT SO FASEB JOURNAL LA English DT Meeting Abstract C1 TRIPLER ARMY MED CTR,DEPT CLIN INVEST,HONOLULU,HI 96859. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A824 EP A824 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19701388 ER PT J AU FREUND, BJ MCKAY, JM YOUNG, AJ OBRIEN, C SAWKA, MN SHODA, GR PANDOLF, KB AF FREUND, BJ MCKAY, JM YOUNG, AJ OBRIEN, C SAWKA, MN SHODA, GR PANDOLF, KB TI CLYCEROL HYPERHYDRATION DOES NOT ALTER THE PRESSOR-RESPONSE TO COLD-EXPOSURE SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,ENVIRONM MED RES INST,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A587 EP A587 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19700009 ER PT J AU GORDON, RK CHIANG, PK AF GORDON, RK CHIANG, PK TI TRIPHOSPHATE ANALOGS OF 3-DEAZAARISTEROMYCIN AND 3-DEAZANEPLANOCIN-A SO FASEB JOURNAL LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DIV BIOCHEM,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 1 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A642 EP A642 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19700335 ER PT J AU HOYT, RW KNAPIK, JJ LANZA, JF JONES, BH STAAB, JS AF HOYT, RW KNAPIK, JJ LANZA, JF JONES, BH STAAB, JS TI AMBULATORY FOOT CONTACT MONITOR TO ESTIMATE THE METABOLIC COST OF HUMAN LOCOMOTION SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,ENVIRONM MED RES INST,NATICK,MA 01760. USA,NATICK RES DEV & ENGN CTR,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A725 EP A725 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19700813 ER PT J AU JOHNSON, K WIESMANN, W PEARCE, FJ AF JOHNSON, K WIESMANN, W PEARCE, FJ TI MODERATE HYPOTHERMIA PROLONGS SURVIVAL DURING HYPOVOLEMIC HYPOTENSION SO FASEB JOURNAL LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A862 EP A862 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19701609 ER PT J AU KIM, IK LEE, JH KIM, HS COPELAND, RL BROWN, ND GARCIA, GE GORDON, RK CHIANG, PK AF KIM, IK LEE, JH KIM, HS COPELAND, RL BROWN, ND GARCIA, GE GORDON, RK CHIANG, PK TI INDUCTION OF APOPTOSIS IN L1210 CELLS BY HIGH-CONCENTRATIONS OF 3-DEAZAADENOSINE ANALOGS SO FASEB JOURNAL LA English DT Meeting Abstract C1 CATHOLIC UNIV,COLL MED,SEOUL 137701,SOUTH KOREA. HOWARD UNIV,COLL MED,WASHINGTON,DC 20001. WALTER REED ARMY INST RES,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A807 EP A807 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19701291 ER PT J AU KOMISAR, JL SMALLHARRIS, SR TSENG, J AF KOMISAR, JL SMALLHARRIS, SR TSENG, J TI LOCALIZATION OF BINDING-SITES OF STAPHYLOCOCCAL ENTEROTOXIN-B (SEB) ON HLA-DR BY INHIBITION WITH SYNTHETIC PEPTIDES OF SEB SO FASEB JOURNAL LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DIV PATHOL,EXPTL PATHOL BRANCH,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A775 EP A775 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19701106 ER PT J AU LUCHETTI, JM MATSUDA, LS CLAYBAUGH, JR UYEHARA, CFT AF LUCHETTI, JM MATSUDA, LS CLAYBAUGH, JR UYEHARA, CFT TI V1 BLOCKADE OF ENDOGENOUS VASOPRESSIN (VP) DURING HYPOXIA EXACERBATES PULMONARY-HYPERTENSION (PHN) IN THE NEONATAL PIGLET SO FASEB JOURNAL LA English DT Meeting Abstract C1 KAPIOLANI MED CTR,HON,HI 96826. TRIPLER ARMY MED CTR,HONOLULU,HI 96859. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A587 EP A587 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19700010 ER PT J AU MADUH, EU NEALLEY, EW WANG, PC SONG, H BASKIN, SI AF MADUH, EU NEALLEY, EW WANG, PC SONG, H BASKIN, SI TI PROTEIN-KINASE-C (PKC) INHIBITION AMELIORATES CYANIDE-STIMULATED CELL ENERGY TRANSIENTS IN BRAIN OF MINIATURE SWINE SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,MED RES INST CHEM DEF,DIV PHARMACOL,ABERDEEN PROVING GROUND,MD 21010. HOWARD UNIV,WASHINGTON,DC 20059. NR 2 TC 1 Z9 1 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A647 EP A647 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19700364 ER PT J AU MATTHEW, CB AF MATTHEW, CB TI HSD TREATMENT OF HEAT-STROKE AND DEHYDRATION EXPANDS PLASMA-VOLUME SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,ENVIRONM MED RES INST,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A587 EP A587 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19700012 ER PT J AU MATYAS, GR ALVING, CR AF MATYAS, GR ALVING, CR TI EFFECT OF ROUTE OF ADMINISTRATION ON GENERATION OF DIFFERENT ISOTYPE ANTIBODIES TO LIPOSOME-ENCAPSULATED RICIN SUBUNITS SO FASEB JOURNAL LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DEPT MEMBRANE BIOCHEM,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A681 EP A681 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19700561 ER PT J AU MOHRI, M SHIRAKI, K LIN, YC TAKEUCHI, H CLAYBAUGH, JR SAGAWA, S HONG, SK AF MOHRI, M SHIRAKI, K LIN, YC TAKEUCHI, H CLAYBAUGH, JR SAGAWA, S HONG, SK TI RENAL AND ENDOCRINE RESPONSES TO SATURATION DIVE IN 3 ATM N2-O2 ENVIRONMENT SO FASEB JOURNAL LA English DT Meeting Abstract C1 JAPAN MARINE SCI & TECHNOL CTR, YOKOSUKA 237, JAPAN. UNIV OCCUPAT & ENVIRONM HLTH, DEPT PHYSIOL, KITAKYUSHU, FUKUOKA 807, JAPAN. UNIV HAWAII, HONOLULU, HI 96822 USA. TRIPLER ARMY MED CTR, HONOLULU, HI 96859 USA. SUNY BUFFALO, BUFFALO, NY 14260 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A845 EP A845 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19701505 ER PT J AU MURPHY, TC HOYT, RW JONES, T GABAREE, C SKIBINSKI, T ASKEW, EW AF MURPHY, TC HOYT, RW JONES, T GABAREE, C SKIBINSKI, T ASKEW, EW TI SUPPLEMENTAL CARBOHYDRATE IMPROVES RUN TO EXHAUSTION TIME IN FAT-PREDOMINANT SOLDIERS SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,TECHNOL RES INST,NATICK,MA 01760. USA,NATICK RES DEV & ENGN CTR,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A726 EP A726 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19700821 ER PT J AU NARAYAN, KA KUPPERSCHMIDT, JB AF NARAYAN, KA KUPPERSCHMIDT, JB TI DEGRADATION OF THIAMIN IN MICROCAPSULES AT HIGH-TEMPERATURES SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,NATICK RES DEV & ENGN CTR,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A705 EP A705 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19700696 ER PT J AU NINDL, BC FRIEDL, KE FRYKMAN, PN MARCHITELLL, LJ SHIPPEE, RL PATTON, JF AF NINDL, BC FRIEDL, KE FRYKMAN, PN MARCHITELLL, LJ SHIPPEE, RL PATTON, JF TI PHYSIOLOGICAL RECOVERY AFTER SEVERE WEIGHT-LOSS SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,ENVIRONM MED RES INST,DIV OCCUPAT PHYSIOL,NATICK,MA 01760. NR 0 TC 3 Z9 3 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A724 EP A724 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19700810 ER PT J AU PEARCE, FJ JOHNSON, K WIESMANN, W AF PEARCE, FJ JOHNSON, K WIESMANN, W TI HYPOTHERMIA (33-DEGREES-C) DURING HEMORRHAGIC-SHOCK (HS) EXTENDS THE THERAPEUTIC WINDOW OF OPPORTUNITY AND PRESERVES RESPONSIVENESS TO VOLUME RESUSCITATION SO FASEB JOURNAL LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A862 EP A862 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19701607 ER PT J AU PORTER, DW BASKIN, SI AF PORTER, DW BASKIN, SI TI 2-MERCAPTOPROPIONIC AND 3-MERCAPTOPROPIONIC ACIDS AFFECT THE ACTIVITY OF THE CYANIDE (CN) DETOXIFYING ENZYME 3-MERCAPTOPYRUVATE SULFURTRANSFERASE (3-MPST) SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,MED RES INST CHEM,DIV PHARMACOL,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A643 EP A643 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19700339 ER PT J AU QIAO, YR KOMISAR, J TSENG, JN AF QIAO, YR KOMISAR, J TSENG, JN TI LYMPHOCYTE AND CYTOKINE RESPONSES IN THE SPLEENS OF MICE INTOXICATED WITH STAPHYLOCOCCAL ENTEROTOXIN-B (SEB) SO FASEB JOURNAL LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DEPT EXPTL PATHOL,WASHINGTON,DC 20307. NR 0 TC 1 Z9 1 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A997 EP A997 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19702384 ER PT J AU ROCKWOOD, GA BASKIN, SI MURROW, ML PREVILLE, JA NEALLEY, EW LEE, RB ROMANO, JA AF ROCKWOOD, GA BASKIN, SI MURROW, ML PREVILLE, JA NEALLEY, EW LEE, RB ROMANO, JA TI THE EFFECTS OF PAPP, PAOP AND PAHP ON SELECTED BLOOD ANALYTES SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,MED RES INST CHEM DEF,DIV DRUG ASSESSMENT & PHARMACOL,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A673 EP A673 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19700515 ER PT J AU SHIPPEE, R FAIRBROTHER, B KRAMER, T ASKEW, E TULLEY, R JEZIOR, D AF SHIPPEE, R FAIRBROTHER, B KRAMER, T ASKEW, E TULLEY, R JEZIOR, D TI NUTRITIONAL AND IMMUNOLOGICAL ASSESSMENT OF SOLDIERS DURING THE SPECIAL FORCES ASSESSMENT AND SELECTION COURSE SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,ENVIRONM MED RES INST,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A949 EP A949 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19702102 ER PT J AU TAYLOR, TJ CREASIA, DA SMITH, NC LECLAIRE, RD LIU, CT BUSHE, TK ELLIOTT, JJ PARKER, GW AF TAYLOR, TJ CREASIA, DA SMITH, NC LECLAIRE, RD LIU, CT BUSHE, TK ELLIOTT, JJ PARKER, GW TI TOXIC RESPONSES TO INTRATRACHEAL CHALLENGE OF STAPHYLOCOCCAL-ENTEROTOXIN B (SEB) IN DUTCH RABBITS SO FASEB JOURNAL LA English DT Meeting Abstract C1 US ARMY MED RES INST INFECT DIS,FT DETRICK,MD 21702. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A900 EP A900 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19701828 ER PT J AU UYEHARA, CFT LUCHETTI, JM CLAYBAUGH, JR NAKAMURA, KT MATSUDA, LS HASHIRO, GM AF UYEHARA, CFT LUCHETTI, JM CLAYBAUGH, JR NAKAMURA, KT MATSUDA, LS HASHIRO, GM TI BENEFICIAL-EFFECTS OF VASOPRESSIN (VP) IN NEWBORN HYPOXIC PULMONARY-HYPERTENSION ARE NOT DEPENDENT UPON NITRIC-OXIDE (NO) SO FASEB JOURNAL LA English DT Meeting Abstract C1 TRIPLER ARMY MED CTR,HONOLULU,HI 96859. KAPIOLANI MED CTR,HONOLULU,HI 96826. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A824 EP A824 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19701386 ER PT J AU VANSCOY, SC UYEHARA, CFT SATO, AK CLAYBAUGH, JR NAKAMURA, KT AF VANSCOY, SC UYEHARA, CFT SATO, AK CLAYBAUGH, JR NAKAMURA, KT TI IMPROVED GAS-EXCHANGE WITH VASOPRESSIN V1-AGONIST (V1) IN NEWBORN PIGLETS IS NOT SEEN WITH OTHER VASOACTIVE AGENTS SO FASEB JOURNAL LA English DT Meeting Abstract C1 TRIPLER ARMY MED CTR,HONOLULU,HI 96859. KAPIOLANI MED CTR,HONOLULU,HI 96826. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A824 EP A824 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19701389 ER PT J AU WENG, CF KOMISAR, JL FRANKLIN, RB TSENG, J AF WENG, CF KOMISAR, JL FRANKLIN, RB TSENG, J TI ENHANCEMENT BY DEXAMETHASONE OF STAPHYLOCOCCAL-ENTEROTOXIN B-INDUCED PROLIFERATION IN MURINE LYMPHOCYTE-CULTURES SO FASEB JOURNAL LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DEPT EXPTL PATHOL,WASHINGTON,DC 20307. UNIV MARYLAND,DEPT PHYSIOL,BALTIMORE,MD 21201. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A1005 EP A1005 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19702428 ER PT J AU WHAUN, JM COPELAND, RL BROWN, ND GARCIA, GE GORDON, RK CHIANG, PK AF WHAUN, JM COPELAND, RL BROWN, ND GARCIA, GE GORDON, RK CHIANG, PK TI EFFECTS OF 3-DEAZANEPLANOCIN A ON DS-19 FRIEND-ERYTHROLEUKEMIA CELLS SO FASEB JOURNAL LA English DT Meeting Abstract C1 US ARMED FORCES RADIOBIOL RES INST,BETHESDA,MD 20889. HOWARD UNIV,COLL MED,WASHINGTON,DC 20059. WALTER REED ARMY INST RES,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 1 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A904 EP A904 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19701848 ER PT J AU WILHELMSEN, C ASSAAD, A AF WILHELMSEN, C ASSAAD, A TI DISTAL ILEAL AND CECAL VASCULAR ECTASIA AND ULCERATION IN FISCHER F344 RATS SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,MED RES INST INFECT DIS,FREDERICK,MD 21702. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR 18 PY 1994 VL 8 IS 5 BP A901 EP A901 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND197 UT WOS:A1994ND19701832 ER PT J AU BARTELS, F BERGEL, H BIGALKE, H FREVERT, J HALPERN, J MIDDLEBROOK, J AF BARTELS, F BERGEL, H BIGALKE, H FREVERT, J HALPERN, J MIDDLEBROOK, J TI SPECIFIC ANTIBODIES AGAINST THE ZN2+-BINDING DOMAIN OF CLOSTRIDIAL NEUROTOXINS RESTORE EXOCYTOSIS IN CHROMAFFIN CELLS TREATED WITH TETANUS OR BOTULINUM A NEUROTOXIN SO JOURNAL OF BIOLOGICAL CHEMISTRY LA English DT Article ID IONIC-STRENGTH SOLUTION; LIGHT CHAIN; NEUROTRANSMITTER RELEASE; INHIBITS EXOCYTOSIS; TOXIN; PROTEINS; GANGLIOSIDES; ZINC AB Although tetanus and botulinum A neurotoxins are ineffective in cultured chromaffin cells, they will inhibit carbachol-induced release of noradrenaline provided they gain access to the cytosol either through artificial pores generated in the plasma membrane or by binding to incorporated exogenous gangliosides. The block of exocytosis persists for weeks followed by a slow recovery of cell function. When specific anti-botulinum A toxin antibodies are introduced into cells through pores after manifestation of the block by botulinum A neurotoxin, restoration of exocytotic function is accelerated and fully reestablished within 4 days. The same time course of restoration is seen with anti-tetanus toxin antibodies in cells poisoned by tetanus toxin. Since the light chains of the toxins are enzymatically active, we have introduced polyclonal and monoclonal anti-light chain antibodies into the cytosol. Of all light chain antibodies tested, only those directed against the peptide homologous to the zinc-binding sequence, which is present in both neurotoxins, restored exocytosis regardless of which toxin caused the block. These results indicate that the zinc-binding domain is directly involved in the interaction of the light chains with their substrates and that the toxins have to be present continuously to maintain the block. C1 MED SCH HANNOVER,INST TOXICOL,D-30625 HANNOVER,GERMANY. PHARMATEC,D-60486 FRANKFURT,GERMANY. US FDA,PUBL HLTH SERV,BETHESDA,MD 20892. USA,MED RES INST INFECT DIS,DIV TOXICOL,FREDERICK,MD 21701. NR 34 TC 37 Z9 39 U1 0 U2 0 PU AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 0021-9258 J9 J BIOL CHEM JI J. Biol. Chem. PD MAR 18 PY 1994 VL 269 IS 11 BP 8122 EP 8127 PG 6 WC Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA NB409 UT WOS:A1994NB40900046 PM 8132537 ER PT J AU CROWLEY, JD HANG, C DALRYMPLE, RE TRINGALI, DR FANK, FB WANDINGER, L WALLACE, HB AF CROWLEY, JD HANG, C DALRYMPLE, RE TRINGALI, DR FANK, FB WANDINGER, L WALLACE, HB TI 140 GHZ INDIUM-PHOSPHIDE GUNN DIODE SO ELECTRONICS LETTERS LA English DT Article DE GUNN DIODES; INDIUM PHOSPHIDE AB An indium phosphide Gunn diode has been developed for operation at 140 GHz. Typical CW performance is 45 mW with 2.3% conversion efficiency at 140 GHz. The highest power obtained was 65 mW with an efficiency of 2.6% at 138 GHz. C1 USA,RES LAB,FT MONMOUTH,NJ 07703. USA,RES LAB,ABERDEEN PROVING GROUND,MD 21010. RP CROWLEY, JD (reprint author), LITTON SOLID STATE,3251 OLCOTT ST,SANTA CLARA,CA 95054, USA. NR 4 TC 16 Z9 16 U1 0 U2 0 PU IEE-INST ELEC ENG PI HERTFORD PA MICHAEL FARADAY HOUSE SIX HILLS WAY STEVENAGE, HERTFORD, ENGLAND SG1 2AY SN 0013-5194 J9 ELECTRON LETT JI Electron. Lett. PD MAR 17 PY 1994 VL 30 IS 6 BP 499 EP 500 DI 10.1049/el:19940358 PG 2 WC Engineering, Electrical & Electronic SC Engineering GA NF924 UT WOS:A1994NF92400030 ER PT J AU KIELY, PA VANG, TA MICOVIC, M LEPORE, A TAYLOR, GW MALIK, R DOCTER, DP EVALDSSON, PA CLAISSE, PR BROWNGOEBELER, KF STORZ, F AF KIELY, PA VANG, TA MICOVIC, M LEPORE, A TAYLOR, GW MALIK, R DOCTER, DP EVALDSSON, PA CLAISSE, PR BROWNGOEBELER, KF STORZ, F TI SUBMICROMETER GATE LENGTH SCALING OF INVERSION CHANNEL HETEROJUNCTION FIELD-EFFECT TRANSISTOR SO ELECTRONICS LETTERS LA English DT Article DE FIELD EFFECT TRANSISTORS; SEMICONDUCTOR DEVICES ID HFET; PERFORMANCE AB The scaling to 0.5mum of the inversion channel HFET with a single strained InGaAs quantum well is described. A unity current gain frequency of 40GHz, g(m) = 205mS/mm and V(TH) = -0.34V have been obtained for 0.5 x 100mum2 devices. For shorter gate lengths, threshold shifts are sizeable so that in order to scale further, modifications to the growth and processing are required. C1 USA,RES LABS,FT MONMOUTH,NJ 07703. AT&T BELL LABS,MURRAY HILL,NJ 07974. RP KIELY, PA (reprint author), AT&T BELL LABS,HOLMDEL,NJ 07733, USA. NR 13 TC 2 Z9 2 U1 0 U2 0 PU IEE-INST ELEC ENG PI HERTFORD PA MICHAEL FARADAY HOUSE SIX HILLS WAY STEVENAGE, HERTFORD, ENGLAND SG1 2AY SN 0013-5194 J9 ELECTRON LETT JI Electron. Lett. PD MAR 17 PY 1994 VL 30 IS 6 BP 529 EP 531 DI 10.1049/el:19940354 PG 3 WC Engineering, Electrical & Electronic SC Engineering GA NF924 UT WOS:A1994NF92400051 ER PT J AU NELSON, RL DAVIS, FG SUTTER, E SOBIN, LH KIKENDALL, JW BOWEN, P AF NELSON, RL DAVIS, FG SUTTER, E SOBIN, LH KIKENDALL, JW BOWEN, P TI BODY IRON STORES AND RISK OF COLONIC NEOPLASIA SO JOURNAL OF THE NATIONAL CANCER INSTITUTE LA English DT Article ID GENETIC HEMOCHROMATOSIS; SERUM FERRITIN; FREE-RADICALS; DIETARY IRON; CANCER; CARCINOGENESIS; SUPPRESSION; METABOLISM; INFECTION; CARCINOMA AB Background: Body iron stores and dietary iron intake have both been shown to be positively associated with subsequent risk of colon cancer. This finding comes from a cohort study involving 14000 men, but the positive association occurred in only 12 cases. Purpose: We performed a case-control study of 264 men and 98 women to test for an association between serum ferritin levels and the presence of adenoma of the colon that would be independent of other known risk factors. Methods: Serum ferritin levels were determined in this study from sera, frozen at -80 degrees C for 5-8 years, that had been originally obtained between 1984-1987 at the Walter Reed Army Medical Center from adult male and postmenopausal female patients undergoing routine colonoscopic examination and previously enrolled in a case-control study that assessed the potential dietary and environmental risk factors for colonic neoplasia. The presence of fecal occult blood in the stool or the suggestion of colonic polyps seen on barium enema defined eligibility for the study. Patients with known preexisting colonic disease were excluded. Eligible patients had their blood drawn and serum prepared. Following colonoscopy and histologic review, the patients were classified into three groups: normal (without neoplastic disease), 159 subjects; adenoma, 145 subjects; and colon cancer, 29 subjects. Body iron stores were determined by measuring serum ferritin levels by a competitive-binding radiometric immunoassay. Ferritin levels categorized into quintiles for adenoma were defined. (OR(adj)) with 95% confidence intervals (CIs) for cancer and adenoma related to ferritin were calculated, controlling for known or suspected risk factors including sex, age, race, body mass index, family history, tobacco use, and alcohol consumption. Results: Statistically significant associations of adenoma risk were seen in the third ([OR(adj)] = 3.8; 95% CI = 1.5-9.5) and fourth (OR(adj) = 5.1; 95% CI = 2.0-12.7) quintiles of ferritin relative to the first quintile, for smoking history (OR(adj) = 2.4; 95% CI = 1.3-4.3), for male sex (OR(adj) = 1.9; CI = 1.0-3.7), and for family history of polyps or cancer (OR(adj) = 1.8; 95% CI = 1.0-3.4). From a second set of analyses that excluded 36 patients with serum ferritin of greater than or equal to 399 ng/mL, the greatest effect of ferritin on adenoma risk by anatomic subsite was seen in the right colon. Conclusion: The apparent dose-response for serum ferritin level and adenoma risk suggest that exposure to iron may be related to adenoma formation. C1 UNIV ILLINOIS,SCH PUBL HLTH,DIV EPIDEMIOL & BIOSTAT,CHICAGO,IL. UNIV ILLINOIS,COLL ASSOCIATED HLTH PROFESS,DEPT NUTR & MED DIETET,CHICAGO,IL. ARMED FORCES INST PATHOL,DIV GASTROINTESTINAL PATHOL,WASHINGTON,DC. WALTER REED ARMY MED CTR,GASTROENTEROL SERV,WASHINGTON,DC 20307. FU NCI NIH HHS [CA36978] NR 41 TC 127 Z9 129 U1 0 U2 1 PU NATL CANCER INSTITUTE PI BETHESDA PA 9030 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0027-8874 J9 J NATL CANCER I JI J. Natl. Cancer Inst. PD MAR 16 PY 1994 VL 86 IS 6 BP 455 EP 460 DI 10.1093/jnci/86.6.455 PG 6 WC Oncology SC Oncology GA NA031 UT WOS:A1994NA03100018 PM 8120921 ER PT J AU LITTLE, SF LEPPLA, SH BURNETT, JW FRIEDLANDER, AM AF LITTLE, SF LEPPLA, SH BURNETT, JW FRIEDLANDER, AM TI STRUCTURE-FUNCTION ANALYSIS OF BACILLUS-ANTHRACIS EDEMA FACTOR BY USING MONOCLONAL-ANTIBODIES SO BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS LA English DT Article ID DEPENDENT ADENYLATE-CYCLASE; PROTECTIVE ANTIGEN; LETHAL TOXIN; BORDETELLA-PERTUSSIS; NUCLEOTIDE-SEQUENCE; BINDING PROPERTIES; EUKARYOTIC CELLS; TRUNCATED FORM; PURIFICATION; COMPONENT AB Edema toxin of Bacillus anthracis is composed of protective antigen (PA) and edema factor (EF), a calcium- and calmodulin-dependent adenylate cyclase. At least five different antigenic regions of EF were identified using a competitive-binding, enzyme-linked immunosorbent assay of paired monoclonal antibodies (mAbs). Two mAbs, 9F5 and 7G10, inhibited the binding of I-125-EF to cell-bound PA, However, only 9F5 inhibited the elongation response of Chinese hamster ovary cells in the presence of edema toxin. Cleavage of EF at the two aspartic acid-proline residues by acid hydrolysis resulted in three fragments: a C-terminal 17 kDa fragment, a central 53 kDa fragment, and an N-terminal 18 kDa fragment. Immunoblots of EF cleaved by formic acid mapped mAbs 9F5 and 7G10 to the N-terminal 18 kDa fragment, mAb 1E6 to the C-terminal 17 kDa fragment, and the remaining 7 mAbs to the central 53 kDa fragment, mAbs 7G10 and 9F5 defined an antigenic region within amino acids 1-156 of EF which is involved in interaction with PA in forming edema toxin. (C) 1994 Academic Press, Inc. C1 UNIV MARYLAND, SCH MED, DEPT DERMATOL, BALTIMORE, MD 21201 USA. RP USA, MED RES INST INFECT DIS, FREDERICK, MD 21702 USA. NR 45 TC 25 Z9 26 U1 1 U2 2 PU ACADEMIC PRESS INC ELSEVIER SCIENCE PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA SN 0006-291X EI 1090-2104 J9 BIOCHEM BIOPH RES CO JI Biochem. Biophys. Res. Commun. PD MAR 15 PY 1994 VL 199 IS 2 BP 676 EP 682 DI 10.1006/bbrc.1994.1281 PG 7 WC Biochemistry & Molecular Biology; Biophysics SC Biochemistry & Molecular Biology; Biophysics GA NA914 UT WOS:A1994NA91400036 PM 8135809 ER PT J AU RABIN, J AF RABIN, J TI SMALL LETTER CONTRAST SENSITIVITY - AN ALTERNATIVE TEST OF VISUAL RESOLUTION SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Meeting Abstract C1 USA,AEROMED RES LAB,FT RUCKER,AL 36360. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD MAR 15 PY 1994 VL 35 IS 4 BP 1259 EP 1259 PG 1 WC Ophthalmology SC Ophthalmology GA MZ585 UT WOS:A1994MZ58500024 ER PT J AU KOTULAK, JC MORSE, SE AF KOTULAK, JC MORSE, SE TI PERCEIVED DISTANCE AFFECTS ACCOMMODATION DURING BINOCULAR VIEWING IF RETINOTOPIC CUES ARE REDUCED SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Meeting Abstract C1 USA,AEROMED RES LAB,FT RUCKER,AL 36360. NR 0 TC 1 Z9 1 U1 0 U2 1 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD MAR 15 PY 1994 VL 35 IS 4 BP 1281 EP 1281 PG 1 WC Ophthalmology SC Ophthalmology GA MZ585 UT WOS:A1994MZ58500133 ER PT J AU SLINEY, DH AF SLINEY, DH TI MODIFICATION OF UV OCULAR EXPOSURE BY PHYSICAL FACTORS SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Meeting Abstract C1 USA,ENVIRONM HYG AGCY,DIV LASER MICROWAVE,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 1 Z9 1 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD MAR 15 PY 1994 VL 35 IS 4 BP 1326 EP 1326 PG 1 WC Ophthalmology SC Ophthalmology GA MZ585 UT WOS:A1994MZ58500329 ER PT J AU PATEL, SC WEINBERG, DV BAUMAN, WC SANNI, N PAVELOFF, M AF PATEL, SC WEINBERG, DV BAUMAN, WC SANNI, N PAVELOFF, M TI COMPARISON OF STEREOSCOPIC AND NONSTEREOSCOPIC FUNDUS PHOTOGRAPHS FOR EVALUATION OF DIABETIC CLINICALLY SIGNIFICANT MACULAR EDEMA SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Meeting Abstract C1 UNIV CHICAGO,DEPT OPHTHALMOL,CHICAGO,IL 60637. NORTHWESTERN UNIV,DEPT OPHTHALMOL,EVANSTON,IL 60201. BROOKE ARMY MED CTR,SAN ANTONIO,TX. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD MAR 15 PY 1994 VL 35 IS 4 BP 1396 EP 1396 PG 1 WC Ophthalmology SC Ophthalmology GA MZ585 UT WOS:A1994MZ58500656 ER PT J AU SCHUSCHEREBA, ST BOWMAN, PD LUND, DJ CROSS, ME AF SCHUSCHEREBA, ST BOWMAN, PD LUND, DJ CROSS, ME TI LONG-TERM CONSEQUENCES OF BASIC FIBROBLAST GROWTH-FACTOR (BFGF) TREATMENT ON LASER-INJURED RABBIT RETINA SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Meeting Abstract C1 USAF,MED RES DETACHMENT,WALTER REED ARMY INST RES,BROOKS AFB,TX 78235. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD MAR 15 PY 1994 VL 35 IS 4 BP 1498 EP 1498 PG 1 WC Ophthalmology SC Ophthalmology GA MZ585 UT WOS:A1994MZ58501122 ER PT J AU RHODES, JW ZUCLICH, JA ZWICK, H GAGLIANO, DA GARCIA, PV LUND, DJ STUCK, BE AF RHODES, JW ZUCLICH, JA ZWICK, H GAGLIANO, DA GARCIA, PV LUND, DJ STUCK, BE TI BULLS-EYE-GAP MACULOPATHY ASSOCIATED WITH REPEATED LARGE-SPOT, Q-SWITCHED LASER EXPOSURES SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Meeting Abstract C1 SW RES INST,SAN ANTONIO,TX 78284. ANALYT SCI CORP,READING,MA. USA,MED RES DETACHMENT,SAN ANTONIO,TX. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD MAR 15 PY 1994 VL 35 IS 4 BP 1516 EP 1516 PG 1 WC Ophthalmology SC Ophthalmology GA MZ585 UT WOS:A1994MZ58501212 ER PT J AU ZWICK, H GAGLIANO, DA LUND, D STUCK, BE AF ZWICK, H GAGLIANO, DA LUND, D STUCK, BE TI TRITAN DEFICITS AND OPHTHALMOSCOPIC LOCALIZATION IN HUMAN PHOTIC MACULOPATHY SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Meeting Abstract C1 USA,MED RES DETACHMENT,SAN ANTONIO,TX. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD MAR 15 PY 1994 VL 35 IS 4 BP 1516 EP 1516 PG 1 WC Ophthalmology SC Ophthalmology GA MZ585 UT WOS:A1994MZ58501213 ER PT J AU GAGLIANO, DA ZUCLICH, JA SCHUSCHEREBA, ST NEMETH, TJ STUCK, BE AF GAGLIANO, DA ZUCLICH, JA SCHUSCHEREBA, ST NEMETH, TJ STUCK, BE TI PATHOLOGY OF LASER-INDUCED RETINAL HEMORRHAGIC LESIONS SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Meeting Abstract C1 USA,MED RES DETACHMENT,SAN ANTONIO,TX 78235. ANALYT SCI CORP,SAN ANTONIO,TX. NR 0 TC 2 Z9 2 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD MAR 15 PY 1994 VL 35 IS 4 BP 1517 EP 1517 PG 1 WC Ophthalmology SC Ophthalmology GA MZ585 UT WOS:A1994MZ58501219 ER PT J AU HOLLIFIELD, RD CAVALLARO, BE WARD, TP WERTZ, FD AF HOLLIFIELD, RD CAVALLARO, BE WARD, TP WERTZ, FD TI INTRAOCULAR TOXICITY OF THE LASER ABSORBING DYES EMPLOYED IN BALLISTIC AND LASER PROTECTIVE SPECTACLES (BLPS) SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Meeting Abstract C1 WALTER REED ARMY MED CTR,OPHTHALMOL SERV,OCULAR TRAUMA RES UNIT,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD MAR 15 PY 1994 VL 35 IS 4 BP 1518 EP 1518 PG 1 WC Ophthalmology SC Ophthalmology GA MZ585 UT WOS:A1994MZ58501225 ER PT J AU PEELE, KA ROSENBERG, ML KOBYLARZ, EJ ROSENBERG, DS AF PEELE, KA ROSENBERG, ML KOBYLARZ, EJ ROSENBERG, DS TI COMPARISON OF PUPILLOGRAPHY TIMING PARADIGMS AND CONSTRICTION PARAMETERS IN AFFERENT PUPILLARY DEFECTS SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Meeting Abstract C1 WALTER REED ARMY MED CTR,WASHINGTON,DC 20307. UNIFORMED ARMY SERV UNIV,BETHESDA,MD. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD MAR 15 PY 1994 VL 35 IS 4 BP 1547 EP 1547 PG 1 WC Ophthalmology SC Ophthalmology GA MZ585 UT WOS:A1994MZ58501369 ER PT J AU BAUMAN, W GAGLIANO, DA ZWICK, H STUCK, BE AF BAUMAN, W GAGLIANO, DA ZWICK, H STUCK, BE TI MACULAR MICROHOLES IN YOUNG MALES SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Meeting Abstract C1 BROOKE ARMY MED CTR,OPHTHALMOL SERV MED RES DETACHMENT,SAN ANTONIO,TX. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD MAR 15 PY 1994 VL 35 IS 4 BP 1713 EP 1713 PG 1 WC Ophthalmology SC Ophthalmology GA MZ585 UT WOS:A1994MZ58502133 ER PT J AU MORSE, SE KOTULAK, JC AF MORSE, SE KOTULAK, JC TI CHROMATIC BANDWIDTH EFFECTS ON ACCOMMODATION SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Meeting Abstract C1 USA,AEROMED RES LAB,FT RUCKER,AL 36360. NR 0 TC 1 Z9 1 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD MAR 15 PY 1994 VL 35 IS 4 BP 1736 EP 1736 PG 1 WC Ophthalmology SC Ophthalmology GA MZ585 UT WOS:A1994MZ58502233 ER PT J AU KLYMENKO, V VERONA, RW MARTIN, JS BEASLEY, HH MCLEAN, W AF KLYMENKO, V VERONA, RW MARTIN, JS BEASLEY, HH MCLEAN, W TI NASO-TEMPORAL RETINAL ASYMMETRY IN DICHOPTIC COMPETITION AND DIPLOPIA SUPPRESSION SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Meeting Abstract C1 US INC,FT RUCKER,AL. USA,AEROMED RES LAB,FT RUCKER,AL 36360. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD MAR 15 PY 1994 VL 35 IS 4 BP 1954 EP 1954 PG 1 WC Ophthalmology SC Ophthalmology GA MZ585 UT WOS:A1994MZ58503238 ER PT J AU KRISHNAMURTI, C VUKELJA, SJ ALVING, BM AF KRISHNAMURTI, C VUKELJA, SJ ALVING, BM TI INHIBITORY EFFECTS OF LYSINE ANALOGS ON T-PA INDUCED WHOLE-BLOOD CLOT LYSIS SO THROMBOSIS RESEARCH LA English DT Article DE LYSINE ANALOGS; WHOLE BLOOD CLOT LYSIS; TISSUE PLASMINOGEN ACTIVATOR; FIBRIN ID TISSUE PLASMINOGEN-ACTIVATOR; EPSILON-AMINOCAPROIC ACID; AMINO CAPROIC ACID; KRINGLE-2 DOMAIN; TRANEXAMIC ACID; FIBRIN; BINDING; FINGER; THROMBOCYTOPENIA; RETRACTION AB The lysine analogues epsilon-aminocaproic acid (EACA) and trans-4-aminomethyl cyclohexane carboxylic acid (AMCA) are used to prevent excessive bleeding in patients with coagulopathies, such as hemophilia and thrombocytopenia, or in those who have received tissue plasminogen activator (t-PA). However, their relative efficacy in inhibiting lysis of clots that have been formed in the presence of exogenous t-PA or that have been formed and then exposed to exogenous t-PA has not been well characterized. The present study utilized blood from normal volunteers and I-125-fibrinogen in a dilute whole blood clot assay to determine the relative concentrations of lysine analogues required for inhibition of clot lysis induced by exogenous t-PA. AMCA(0.06 mM) and EACA (0.6 mM) were effective in prolonging clot lysis if (1) whole blood clots were formed and then exposed to a lysine analogue and exogenous t-PA or if (2) whole blood clots were formed in the presence of exogenous t-PA and a lysine analogue, However, their inhibitory effect was markedly reduced if clots were formed in the presence of t-PA and then exposed to either of the lysine analogues. The analogues did not inhibit the initial binding of t-PA to fibrin. They did inhibit binding of plasminogen to fibrin as well as the activation of plasminogen by t-PA in the absence of fibrin. The data suggest that lysine analogues, even at low concentrations, reduce the rate of t-PA induced whole blood clot lysis by several mechanisms. C1 BROOKE ARMY MED CTR,FT SAM HOUSTON,TX. RP KRISHNAMURTI, C (reprint author), WALTER REED ARMY INST RES,DEPT HEMATOL,WASHINGTON,DC 20307, USA. NR 30 TC 18 Z9 19 U1 0 U2 1 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0049-3848 J9 THROMB RES JI Thromb. Res. PD MAR 15 PY 1994 VL 73 IS 6 BP 419 EP 430 DI 10.1016/0049-3848(94)90043-4 PG 12 WC Hematology; Peripheral Vascular Disease SC Hematology; Cardiovascular System & Cardiology GA MZ842 UT WOS:A1994MZ84200006 PM 8073394 ER PT J AU YANG, YC AF YANG, YC TI OXIDATIVE DETOXIFICATION OF CHEMICAL WARFARE AGENTS SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,EDGEWOOD RES DEV & ENGN CTR,RES & TECHNOL DIRECTORATE,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 0 Z9 0 U1 1 U2 2 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 3 EP INOR PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95402764 ER PT J AU MUNAVALLI, S ROSSMAN, DI SZAFRANIEC, LL BEAUDRY, WT ROHRBAUGH, DK FERGUSON, CP GRATZEL, M AF MUNAVALLI, S ROSSMAN, DI SZAFRANIEC, LL BEAUDRY, WT ROHRBAUGH, DK FERGUSON, CP GRATZEL, M TI SYNTHESIS OF 2,2'-BIPYRIDYLS VIA OXIDATIVE COUPLING AND MODIFIED ULLMAN REACTION SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 GEOCENTERS INC,FT WASHINGTON,MD 20774. USA,EDGEWOOD RES DEV ENGN CTR,ABERDEEN PROVING GROUND,MD 21010. ECOLE POLYTECH FED LAUSANNE,INST CHIM PHYS,CH-1015 LAUSANNE,SWITZERLAND. RI Graetzel, Michael/G-4870-2011 NR 0 TC 0 Z9 0 U1 0 U2 1 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 18 EP FLUO PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95402189 ER PT J AU MCFARLAND, VA AF MCFARLAND, VA TI PREDICTIVE CAPABILITY OF FIELD-GENERATED POLYNUCLEAR AROMATIC HYDROCARBON (PAH) ACCUMULATION FACTORS SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USAE,WATERWAYS EXPT STN,ENVIRONM LAB,VICKSBURG,MS 39180. NR 0 TC 0 Z9 0 U1 1 U2 1 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 19 EP ENVR PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95401926 ER PT J AU BRANNON, JM PENNINGTON, JC DAVIS, WH MYERS, TE HAYES, C AF BRANNON, JM PENNINGTON, JC DAVIS, WH MYERS, TE HAYES, C TI K(DOC) IN PORE-WATER AND SEDIMENT EXTRACTS SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,CORPS ENGINEERS,WATERWAYS EXPT STN,ENVIRONM LAB,VICKSBURG,MS 39180. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 20 EP ENVR PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95401927 ER PT J AU LANGFORD, RE AF LANGFORD, RE TI ROLE OF RESEARCH IN THE ARMY HEALTH-HAZARD ASSESSMENT PROGRAM SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,MED RES DETACHMENT,WRIGHT PATTERSON AFB,OH. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 30 EP CHAS PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95401347 ER PT J AU COMMONS, BJ ROBERTS, WC ABERNATHY, CO KHANNA, K AF COMMONS, BJ ROBERTS, WC ABERNATHY, CO KHANNA, K TI RISK ASSESSMENT OF MUNITIONS CHEMICALS AS DRINKING-WATER CONTAMINANTS SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 US EPA,HUMAN RISK ASSESSMENT BRANCH,WASHINGTON,DC 20460. USA,DEPT MED,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 31 EP CHAS PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95401348 ER PT J AU SMITH, JS COMEAU, J ROSE, C SCHULTE, B BARCELONA, M KLOPP, C FREEMAN, MJ MINNICH, M FEENSTRA, S URBAN, M MOORE, MB HEWITT, A MASKARINEC, M SIEGRIST, B PARR, J CLAFF, RE AF SMITH, JS COMEAU, J ROSE, C SCHULTE, B BARCELONA, M KLOPP, C FREEMAN, MJ MINNICH, M FEENSTRA, S URBAN, M MOORE, MB HEWITT, A MASKARINEC, M SIEGRIST, B PARR, J CLAFF, RE TI ACCURATE AND REPRESENTATIVE ANALYSIS OF VOCS IN SOIL SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 TRILLIUM INC,COATESVILLE,PA 19320. AQUATEC,COLCHESTER,VT. ARGONNE NATL LAB,ARGONNE,IL 60439. DNREC,NEW CASTLE,DE. WESTERN MICHIGAN UNIV,DEPT CHEM,KALAMAZOO,MI 49008. WISCONSIN DEPT NAT RESOURCES,MADISON,WI. ALASKA DEPT ENVIRONM CONSERVAT,JUNEAU,AK. US EPA LOCKHEED,DIV ENVIRONM SCI & TECHNOL,LAS VEGAS,NV. APPL GROUNDWATER RES LTD,MISSISSAUGA,ON,CANADA. ENVIROTECH RES,EDISON,NJ. ENSR CONSULTING & ENGN,ACTON,MA. USA,CRREL,HANOVER,NH 03755. OAK RIDGE NATL LAB,OAK RIDGE,TN 37830. ENSECO,ROCKY MT ANALYT LAB,ARVADA,CO. AMER PETR INST,WASHINGTON,DC. NR 0 TC 0 Z9 0 U1 0 U2 1 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 33 EP CEI PN 2 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY955 UT WOS:A1994MY95502043 ER PT J AU ABERNATHY, CO COMMONS, BJ POIRIER, KA AF ABERNATHY, CO COMMONS, BJ POIRIER, KA TI RISK ASSESSMENT OF SOME ESSENTIAL TRACE-ELEMENTS (ETES) USING ZINC (ZN) AS AN EXAMPLE SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 US EPA,HUMAN RISK ASSESSMENT BRANCH 4304,WASHINGTON,DC 20460. USA,WASHINGTON,DC 20310. PROCTER & GAMBLE CO,CINCINNATI,OH 45239. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 34 EP CHAS PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95401351 ER PT J AU ASHMAN, WP MEEHAN, BS AF ASHMAN, WP MEEHAN, BS TI MOLECULAR MODELING OF THE INTERACTION OF HIGHLY TOXIC COMPOUNDS WITH ACETYLCHOLINESTERASE SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,EDGEWOOD RES DEV & ENGN CTR,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 36 EP COMP PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95401754 ER PT J AU ELDEFRAWI, ME DEVINE, PJ ANIS, NA VALDES, JJ ROGERS, KR AF ELDEFRAWI, ME DEVINE, PJ ANIS, NA VALDES, JJ ROGERS, KR TI RECEPTOR AND ANTIBODY-BASED FIBER OPTIC EVANESCENT BIOSENSORS SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 UNIV MARYLAND,SCH MED,DEPT PHARMACOL & EXPTL THERAPEUT,BALTIMORE,MD 21201. USA,EDGEWOOD RD & E CTR,SCBRD RT,ABERDEEN PROVING GROUND,MD 21010. US EPA,EMSL LV,EAD,LAS VEGAS,NV 89193. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 40 EP BTEC PN 2 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY955 UT WOS:A1994MY95501783 ER PT J AU NOWACK, CJ AF NOWACK, CJ TI PROPOSED UNIVERSAL RATE-CONSTANT FOR QUANTIFYING JET FUEL THERMAL DEPOSITION SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,CTR AIR WARFARE,DIV AIRCRAFT,TRENTON,NJ 08628. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 41 EP PETR PN 2 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY955 UT WOS:A1994MY95500610 ER PT J AU MINARD, RD LIEBMAN, SA PESCERODRIGUEZ, RA MATTHEWS, CN AF MINARD, RD LIEBMAN, SA PESCERODRIGUEZ, RA MATTHEWS, CN TI TRACE ORGANIC-ANALYSIS OF HYDROGEN-CYANIDE POLYMERS AND RELEVANCE TO PREBIOTIC CHEMISTRY SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 PENN STATE UNIV,DEPT CHEM,UNIV PK,PA 16802. USA,RES LAB,ABERDEEN PROVING GROUND,MD 21005. CCS INSTRUMENT SYST,W GROVE,PA 19390. UNIV ILLINOIS,DEPT CHEM,CHICAGO,IL 60680. NR 0 TC 0 Z9 0 U1 1 U2 1 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 46 EP GEOC PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95402399 ER PT J AU MELLO, CM ARCIDIACONO, S SENECAL, K MCGRATH, K BECKWITT, R KAPLAN, DL AF MELLO, CM ARCIDIACONO, S SENECAL, K MCGRATH, K BECKWITT, R KAPLAN, DL TI SPIDER SILK - NATURES HIGH-PERFORMANCE FIBER SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,NATICK RES DEV & ENGN CTR,DIV BIOTECHNOL,NATICK,MA 01760. RI Senecal, Kris/F-3000-2013 NR 0 TC 3 Z9 3 U1 0 U2 4 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 80 EP BTEC PN 2 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY955 UT WOS:A1994MY95501823 ER PT J AU FAMINI, GR HEADLEY, AD WILSON, L AF FAMINI, GR HEADLEY, AD WILSON, L TI USING THEORETICAL DESCRIPTORS IN QSAR AND LFER - THE ROLE OF SOLUTE SOLVENT INTERACTIONS IN SOLUBILITY, ACIDITY AND BASICITY SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,EDGEWOOD RES DEV & ENGN CTR,ABERDEEN PROVING GROUND,MD 21010. TEXAS TECH UNIV,DEPT CHEM,LUBBOCK,TX 79409. LA SIERRA UNIV,DEPT CHEM,RIVERSIDE,CA 92515. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 96 EP COMP PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95401814 ER PT J AU ACAR, YB PUPPALA, S MARKS, RE GALE, RJ BRICKA, M AF ACAR, YB PUPPALA, S MARKS, RE GALE, RJ BRICKA, M TI AN ASSESSMENT OF SELECTED ENHANCEMENT TECHNIQUES IN ELECTROKINETIC REMEDIATION OF INORGANIC SPECIES SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 LOUISIANA STATE UNIV,ELECTROKINETICS INC,BATON ROUGE,LA 70803. USA,CORPS ENGINEERS,VICKSBURG,MS 39180. LOUISIANA STATE UNIV,DEPT CIVIL ENGN,BATON ROUGE,LA 70803. LOUISIANA STATE UNIV,DEPT CHEM,BATON ROUGE,LA 70803. NR 0 TC 1 Z9 1 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 116 EP ENVR PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95402023 ER PT J AU HUANG, XL FAMINL, GR AF HUANG, XL FAMINL, GR TI THE QUANTUM-MECHANICAL STUDY OF THE REACTIVITY OF PHOSPHATE IN THE GAS-PHASE AND IN AQUEOUS-SOLUTION SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,EDGEWOOD RES DEV & ENGN CTR,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 119 EP COMP PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95401836 ER PT J AU DONOVAN, WH FAMINI, GR AF DONOVAN, WH FAMINI, GR TI AB-INITIO STUDY OF CENTER-DOT-H, CENTER-DOT-OH, CENTER-DOT-NH2 AND CENTER-DOT-CH3 ADDITION TO MONOFLUOROETHYLENE AND 1,1-DIFLUOROETHYLENE SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,EDGEWOOD RES DEV & ENGN CTR,SCBRD RTC,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 120 EP COMP PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95401837 ER PT J AU ELDEFRAWI, ME ANIS, NA ROGERS, KR WONG, R VALDES, JJ AF ELDEFRAWI, ME ANIS, NA ROGERS, KR WONG, R VALDES, JJ TI REUSABLE RAPID FIBEROPTIC IMMUNOSENSORS FOR DETECTION OF PESTICIDES SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 UNIV MARYLAND,SCH MED,DEPT PHARMACOL,BALTIMORE,MD 21201. US EPA,EMSL LV,LAS VEGAS,NV 89193. USA,EDGEWOOD RD & E CTR,ABERDEEN PROVING GROUND,MD 21010. AMER CYANAMID CO,DIV AGR RES,PRINCETON,NJ 08543. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 153 EP AGRO PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95400225 ER PT J AU ROESSER, DS MCCARTHY, SP GROSS, RA KAPLAN, DL BALL, D AF ROESSER, DS MCCARTHY, SP GROSS, RA KAPLAN, DL BALL, D TI EFFECTS OF SITE-SELECTIVE AMYLOSE MODIFICATION ON BIODEGRADATION BY ALPHA-AMYLASE FROM BACILLUS-SUBTILIS AND ASPERGILLUS-ORYZAE SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 UNIV MASSACHUSETTS,DEPT CHEM,LOWELL,MA 01854. UNIV MASSACHUSETTS,DEPT PL ENGN,LOWELL,MA 01854. USA,NATICK RD&E CTR,DIV BIOTECHNOL,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 155 EP BTEC PN 2 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY955 UT WOS:A1994MY95501898 ER PT J AU LINDSAY, GA HERMAN, WN ASHLEY, PR LEE, CYC AF LINDSAY, GA HERMAN, WN ASHLEY, PR LEE, CYC TI APPLICATIONS FOR POLYMERIC NONLINEAR OPTICS IN THE MILITARY SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USAF,AFOSR AFMC,BOLLING AFB,DC. USN,NAWCWPNS,CHINA LAKE,CA 93555. USN,NAWCAD,WARMINSTER,PA 18974. USA,MISSILE RES & DEV COMMAND,REDSTONE ARSENAL,AL 35809. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 156 EP IEC PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95402702 ER PT J AU MELLO, C FOSSEY, S MCGRATH, K ARCIDIACONO, S SENECAL, K NALDRETT, M PRINCE, J KAPLAN, D AF MELLO, C FOSSEY, S MCGRATH, K ARCIDIACONO, S SENECAL, K NALDRETT, M PRINCE, J KAPLAN, D TI HIGHLY REPETITIVE PROTEINS - STRUCTURE, FUNCTION, GENETICS SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,NATICK RES DEV & ENGN CTR,NATICK,MA 01760. RI Senecal, Kris/F-3000-2013 NR 0 TC 0 Z9 0 U1 0 U2 2 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 168 EP IEC PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95402714 ER PT J AU MUSALLAM, HA FOYE, WO HANSCH, C HARRIS, RN ENGLE, RR AF MUSALLAM, HA FOYE, WO HANSCH, C HARRIS, RN ENGLE, RR TI QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS OF IMIDAZOLIUM OXIMES AS NERVE AGENT ANTIDOTES SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 177 EP MEDI PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95403483 ER PT J AU AKKARA, JA KAPLAN, D AF AKKARA, JA KAPLAN, D TI CHARACTERIZATION OF POLYANILINE SYNTHESIZED BY ENZYME-CATALYZED REACTION IN ORGANIC-SOLVENTS SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,NATICK RES & DEV LABS,CTR DEV & ENGN,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 209 EP BIOT PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95400607 ER PT J AU MACDONALD, RT GROSS, RA SWIFT, G KAPLAN, DL AKKARA, J AF MACDONALD, RT GROSS, RA SWIFT, G KAPLAN, DL AKKARA, J TI ENZYME-CATALYZED POLYMERIZATION OF EPSILON-CAPROLACTONE SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,NATICK RES & DEV LABS,CTR DEV & ENGN,NATICK,MA 01760. UNIV MASSACHUSETTS,DEPT CHEM,LOWELL,MA 01854. ROHM & HAAS CO,SPRING HOUSE,PA 19477. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 219 EP BIOT PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95400617 ER PT J AU HSU, FL ZHANG, XY BERG, FJ MILLER, DD AF HSU, FL ZHANG, XY BERG, FJ MILLER, DD TI IMIDAZOLE-ASSISTED INTRAMOLECULAR PHENOXYTHIOCARBONYLATION OF TERTIARY ALCOHOLS - A KEY REACTION FOR THE DEOXYGENATION OF TRIFLUOROMETHYL CARBINOLS SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,EDGEWOOD RES DEV & ENGN CTR,ABERDEEN PROVING GROUND,MD 21010. OHIO STATE UNIV,COLL PHARM,DIV MED CHEM & PHARMACOGNOSY,COLUMBUS,OH 43210. UNIV TENNESSEE CTR HLTH SCI,DEPT PHARMACEUT SCI,MEMPHIS,TN 38163. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 257 EP ORGN PN 2 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY955 UT WOS:A1994MY95500334 ER PT J AU KELLEY, C YODER, JC AF KELLEY, C YODER, JC TI CYCLIC VOLTAMMETRY AS A TECHNIQUE TO PREDICT THE METHEMOGLOBIN FORMING CAPACITY OF P-AMINOALKYLPHENONES AND 8-AMINOQUINOLINES SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DIV EXPTL THERAPEUT,DEPT MED CHEM,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 1 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 263 EP MEDI PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95403567 ER PT J AU ACTON, N ROTH, RJ AF ACTON, N ROTH, RJ TI ACID DECOMPOSITION OF THE ANTIMALARIAL BETA-ARTEETHER SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307. GEORGE MASON UNIV,DEPT CHEM,FAIRFAX,VA 22030. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 266 EP ORGN PN 2 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY955 UT WOS:A1994MY95500343 ER PT J AU MUNAVALLI, S HASSNER, A ROSSMAN, DI SINGH, S ROHRBAUGH, DK FERGUSON, CP AF MUNAVALLI, S HASSNER, A ROSSMAN, DI SINGH, S ROHRBAUGH, DK FERGUSON, CP TI METALATION OF PERFLUOROALKYLPHENYL SULFIDES SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,CTR RES DEV & ENGN,ABERDEEN PROVING GROUND,MD 21010. BAR ILAN UNIV,DEPT CHEM,IL-52900 RAMAT GAN,ISRAEL. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 357 EP ORGN PN 2 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY955 UT WOS:A1994MY95500433 ER PT J AU CHEN, MF VEZZOLI, GC AF CHEN, MF VEZZOLI, GC TI MOLTEN-SALT SYNTHESIS PREPARATION AND PROCESSING OF LEAD-MAGNESIUM-NIOBATE CERAMICS FOR HIGH DIELECTRIC STRENGTH MATERIALS SO ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY LA English DT Meeting Abstract C1 USA,RES LAB,DIV CERAM & MET,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 1 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0065-7727 J9 ABSTR PAP AM CHEM S JI Abstr. Pap. Am. Chem. Soc. PD MAR 13 PY 1994 VL 207 BP 377 EP INOR PN 1 PG 0 WC Chemistry, Multidisciplinary SC Chemistry GA MY954 UT WOS:A1994MY95403137 ER PT J AU KANESATHASAN, N IACONOCONNORS, L MAGILL, A SMOAK, B VAUGHN, D DUBOIS, D BURROUS, J HOKE, C AF KANESATHASAN, N IACONOCONNORS, L MAGILL, A SMOAK, B VAUGHN, D DUBOIS, D BURROUS, J HOKE, C TI DENGUE SEROTYPE-2 AND SEROTYPE-3 IN US FORCES IN SOMALIA SO LANCET LA English DT Letter ID VIRUSES C1 WALTER REED ARMY INST RES,DIV PREVENT MED,WASHINGTON,DC 20307. ARMED FORCES RES INST MED SCI,DEPT VIROL,BANGKOK,THAILAND. RP KANESATHASAN, N (reprint author), WALTER REED ARMY INST RES,DIV COMMUNICABLE DIS & IMMUNOL,WASHINGTON,DC 20307, USA. NR 5 TC 21 Z9 24 U1 0 U2 0 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD MAR 12 PY 1994 VL 343 IS 8898 BP 678 EP 678 DI 10.1016/S0140-6736(94)92678-6 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA NA093 UT WOS:A1994NA09300056 PM 7906846 ER PT J AU BELLAMY, RF AF BELLAMY, RF TI REVIEW OF THE FACE OF MERCY SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Letter RP BELLAMY, RF (reprint author), WALTER REED ARMY MED CTR,WASHINGTON,DC 20307, USA. NR 4 TC 0 Z9 0 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD MAR 9 PY 1994 VL 271 IS 10 BP 749 EP 749 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA MY288 UT WOS:A1994MY28800027 ER PT J AU TIDROW, MZ CHOI, KK LEE, CY CHANG, WH TOWNER, FJ AHEARN, JS AF TIDROW, MZ CHOI, KK LEE, CY CHANG, WH TOWNER, FJ AHEARN, JS TI VOLTAGE TUNABLE 3-COLOR QUANTUM-WELL INFRARED PHOTODETECTOR SO APPLIED PHYSICS LETTERS LA English DT Article ID DETECTOR; SENSITIVITY AB A voltage tunable three-color quantum well infrared photodetector (QWIP) consisting of asymmetric GaAs/AlGaAs double quantum wells has been demonstrated. The detector uses electron intersubband transitions in a coupled asymmetric double quantum well superlattice. The infrared photocurrent spectrum characterized using a blackbody monochromator source shows three prominent peaks appearing at 8.4 mum, 9.6 mum, and 10.3 mum under different biases. The three detection peaks are well resolved and can be independently selected by tuning the applied voltage. The responsivity and the detectivity of the detector at different biases and operating temperatures are characterized and found to be sufficient for detector operation at temperatures approximately 60 K. C1 MARTIN MARIETTA CORP LABS,BALTIMORE,MD 21227. RP TIDROW, MZ (reprint author), USA,RES LAB,EPSD,FT MONMOUTH,NJ 07703, USA. RI Choi, Kwong-Kit/K-9205-2013 NR 22 TC 24 Z9 24 U1 0 U2 2 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD MAR 7 PY 1994 VL 64 IS 10 BP 1268 EP 1270 DI 10.1063/1.110861 PG 3 WC Physics, Applied SC Physics GA MZ171 UT WOS:A1994MZ17100032 ER PT J AU CORMIER, G CAPOBIANCO, JA MORRISON, CA AF CORMIER, G CAPOBIANCO, JA MORRISON, CA TI INFLUENCE OF STRUCTURE ON THE OPTICAL-SPECTRA OF EU3+ IN PB(PO3)2 GLASS - MOLECULAR-DYNAMICS SIMULATION AND CRYSTAL-FIELD THEORY SO JOURNAL OF THE CHEMICAL SOCIETY-FARADAY TRANSACTIONS LA English DT Article ID PHOSPHATE-GLASSES; SILICATE-GLASSES; FLUORIDE GLASSES; LASER GLASS; SPECTROSCOPY; ABSORPTION; ND-3+; EU-3+ AB An investigation of the structural factors which lead to the marked differences between various spectral features of rare-earth-metal ions doped in metal metaphosphate and silicate glasses is reported. The investigation was based on a simulated structural/spectral model of an Eu3+-doped lead metaphosphate glass [Eu3+ : Pb(PO3)2] that was compared to a previously reported Eu3+-doped sodium disilicate glass [Eu3+ : Na2Si2O5]. The models were generated with a computational method that couples molecular dynamics simulation and point-charge crystal-field calculations. It is proposed that the marked differences in several spectroscopic features of Eu3+ ions doped in a lead metaphosphate glass are essentially due to a reduction in the width of the energetic distribution of local fields experienced by the Eu3+ ions. This distribution is shown to be influenced considerably by the presence of medium-range order in the local environment of the Eu3+ ions due to the lack of rigidity of the phosphate backbone. C1 CONCORDIA UNIV,DEPT CHEM & BIOCHEM,1455 MAISONNEUVE BLVD W,MONTREAL H3G 1M8,QUEBEC,CANADA. USA,RES LAB,DIV MICROPHOTON,ADELPHI,MD 20783. NR 46 TC 21 Z9 21 U1 0 U2 1 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK MILTON ROAD, CAMBRIDGE, CAMBS, ENGLAND CB4 4WF SN 0956-5000 J9 J CHEM SOC FARADAY T JI J. Chem. Soc.-Faraday Trans. PD MAR 7 PY 1994 VL 90 IS 5 BP 755 EP 762 DI 10.1039/ft9949000755 PG 8 WC Chemistry, Physical; Physics, Atomic, Molecular & Chemical SC Chemistry; Physics GA NB140 UT WOS:A1994NB14000013 ER PT J AU BECKWITT, R ARCIDIACONO, S AF BECKWITT, R ARCIDIACONO, S TI SEQUENCE CONSERVATION IN THE C-TERMINAL REGION OF SPIDER SILK PROTEINS (SPIDROIN) FROM NEPHILA-CLAVIPES (TETRAGNATHIDAE) AND ARANEUS-BICENTENARIUS (ARANEIDAE) SO JOURNAL OF BIOLOGICAL CHEMISTRY LA English DT Article ID SECONDARY-STRUCTURE; DRAGLINE SILK AB The polymerase chain reaction (PCR) has been used to amplify the portion of the Spidroin 1 gene that codes for the C-terminal part of the silk protein of the spider Nephila clavipes, Along with some substitution mutations of minor consequence, the PCR derived sequence reveals an additional base missing from the previously published Nephila Spidroin 1 sequence. Comparison of the PCR-derived sequence with the equivalent region of Spidroin 2 indicates that the insertion of this single base results in greatly increased similarity in the resulting amino acid sequences of Spidroin 1 and Spidroin 2 (75% over 97 amino acids). The same PCR primers also amplified a fragment of the same length from Araneus bicentenarius. This sequence is also very similar to Spidroin 1 of Nephila (71% over 238 bases excluding the PCR primers, which translates into 76% over 79 amino acids). C1 USA,NATICK RES DEV & ENGN CTR,DIV BIOTECHNOL,NATICK,MA 01760. FRAMINGHAM STATE COLL,DEPT BIOL,FRAMINGHAM,MA 01701. NR 10 TC 72 Z9 76 U1 0 U2 3 PU AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 0021-9258 J9 J BIOL CHEM JI J. Biol. Chem. PD MAR 4 PY 1994 VL 269 IS 9 BP 6661 EP 6663 PG 3 WC Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA MZ503 UT WOS:A1994MZ50300064 PM 8120021 ER PT J AU GRIEGER, TA COZZA, K ARMSTRONG, S AF GRIEGER, TA COZZA, K ARMSTRONG, S TI TREATMENT OF PARKINSONS-DISEASE SO NEW ENGLAND JOURNAL OF MEDICINE LA English DT Letter ID ELECTROCONVULSIVE-THERAPY C1 WALTER REED ARMY MED CTR,WASHINGTON,DC 20307. RP GRIEGER, TA (reprint author), UNIFORMED SERV UNIV HLTH SCI,BETHESDA,MD 20814, USA. NR 5 TC 1 Z9 1 U1 0 U2 0 PU MASS MEDICAL SOC PI BOSTON PA 10 SHATTUCK, BOSTON, MA 02115 SN 0028-4793 J9 NEW ENGL J MED JI N. Engl. J. Med. PD MAR 3 PY 1994 VL 330 IS 9 BP 643 EP 644 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA MY573 UT WOS:A1994MY57300026 PM 8302357 ER PT J AU ROLLEFSON, WA WINSLOW, TM ADAMS, CW DANG, MH AF ROLLEFSON, WA WINSLOW, TM ADAMS, CW DANG, MH TI TRAUMATIC DEHISCENCE OF A TRICUSPID ANNULOPLASTY RING - DIAGNOSIS BY TRANSESOPHAGEAL ECHOCARDIOGRAPHY SO AMERICAN HEART JOURNAL LA English DT Note ID INSUFFICIENCY C1 TRIPLER ARMY MED CTR,DEPT MED,CARDIOL SERV,HONOLULU,HI 96859. TRIPLER ARMY MED CTR,DEPT SURG,CARDIOTHORAC SURG SERV,HONOLULU,HI 96859. NR 6 TC 2 Z9 2 U1 0 U2 0 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0002-8703 J9 AM HEART J JI Am. Heart J. PD MAR PY 1994 VL 127 IS 3 BP 708 EP 710 DI 10.1016/0002-8703(94)90689-0 PG 3 WC Cardiac & Cardiovascular Systems SC Cardiovascular System & Cardiology GA NA088 UT WOS:A1994NA08800036 PM 8122628 ER PT J AU SCHIERMEYER, RP FINKELSTEIN, JA AF SCHIERMEYER, RP FINKELSTEIN, JA TI RAPID INFUSION OF MAGNESIUM-SULFATE OBVIATES NEED FOR INTUBATION IN STATUS-ASTHMATICUS SO AMERICAN JOURNAL OF EMERGENCY MEDICINE LA English DT Note DE ASTHMA; MAGNESIUM C1 WILFORD HALL USAF MED CTR,BROOKE ARMY MED CTR,EMERGENCY MED RESIDENCY PROGRAM,JOINT MIL MED CTR,SAN ANTONIO,TX. NR 0 TC 34 Z9 34 U1 0 U2 0 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0735-6757 J9 AM J EMERG MED JI Am. J. Emerg. Med. PD MAR PY 1994 VL 12 IS 2 BP 164 EP 166 DI 10.1016/0735-6757(94)90238-0 PG 3 WC Emergency Medicine SC Emergency Medicine GA NC364 UT WOS:A1994NC36400009 PM 8161388 ER PT J AU SMOAK, BL KELLEY, PW TAYLOR, DN AF SMOAK, BL KELLEY, PW TAYLOR, DN TI SEROPREVALENCE OF HELICOBACTER-PYLORI INFECTIONS IN A COHORT OF US ARMY RECRUITS SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Article DE HELICOBACTER PYLORI; RISK FACTORS ID GASTRIC-CARCINOMA; EPIDEMIOLOGY; POPULATION; AGE AB To study the prevalence and risk factors of Helicobacter pylori infection in healthy young adults, sera were collected from a nationwide sample of 404 females and 534 males (mean age, 20.2; range, 17-26 years) at induction into the US Army at Fort Jackson, South Carolina, during the fall of 1990. An enzyme-linked immunosorbent assay (PYLORI STAT, BioWhittaker, Inc., Walkersville, MD) was used to detect H. pylori-specific immunoglobulin G antibodies. Demographic data were obtained from a personnel database and by linking US census information to the subject's home address. The observed crude seropositivity rate was 26.3% (95% confidence interval 23.2-28.9). The direct sex-, race-, and geographic region-adjusted seropositivity rate was 20.8% (95% confidence interval 17.9-23.7). Seropositivity rates for blacks, Hispanics, and whites were 44%, 38%, and 14%, respectively, (chi(2), p < 0.001), and rates increased progressively from 24% in the age group 17-18 years to 43% in the age group 24-26 years (chi(2) for trend, p < 0.001). The age trends remained strong after controlling for race Median income was also an important predictive variable for seropositivity (chi(2) p < 0.0001). Sex, the percent urbanization, and population density of the home county were not significant predictors of seropositivity when age and race-ethnic group were controlled in a statistical model. The sharp increase in seroprevalence in this narrow age range suggests that the incidence rates are higher in young adults than previously reported. C1 WALTER REED ARMY INST RES,DEPT ENTER INFECT,DIV COMMUNICABLE DIS & IMMUNOL,WASHINGTON,DC. RP SMOAK, BL (reprint author), WALTER REED ARMY MED CTR,WALTER REED ARMY INST RES,DIV PREVENT MED,WASHINGTON,DC 20307, USA. NR 19 TC 42 Z9 43 U1 0 U2 0 PU JOHNS HOPKINS UNIV SCHOOL HYGIENE PUB HEALTH PI BALTIMORE PA 111 MARKET PLACE, STE 840, BALTIMORE, MD 21202-6709 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD MAR 1 PY 1994 VL 139 IS 5 BP 513 EP 519 PG 7 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA NF164 UT WOS:A1994NF16400007 PM 8154475 ER PT J AU HOYT, RW JONES, TE BAKERFULCO, CJ SCHOELLER, DA SCHOENE, RB SCHWARTZ, RS ASKEW, EW CYMERMAN, A AF HOYT, RW JONES, TE BAKERFULCO, CJ SCHOELLER, DA SCHOENE, RB SCHWARTZ, RS ASKEW, EW CYMERMAN, A TI DOUBLY LABELED WATER MEASUREMENT OF HUMAN ENERGY-EXPENDITURE DURING EXERCISE AT HIGH-ALTITUDE SO AMERICAN JOURNAL OF PHYSIOLOGY LA English DT Article DE BODY COMPOSITION; FOOD INTAKE ENERGY BALANCE; FIELD STUDY; ENERGY DEFICIT ID BODY-WATER; DETERMINANT; WOMEN AB Estimates of total daily energy expenditure (TDEE) by the doubly labeled water (DLW, (H2O)-H-2-O-18) and intake balance (I-B) methods were compared in six male soldiers studied over 6 days that included 5 days of strenuous winter exercise at 2,500- to 3,100-m elevation. Use of body energy stores [-9.54 +/- 1.54 (SD) MJ/day or -2,280 +/- 368 kcal/day] was estimated from changes in body weight, body density (hydrodensitometry), and total body water ((H2O)-O-18 dilution). The subjects wore computerized activity monitors and kept daily records of ration consumption (9.87 +/- 3.60 MJ/day or 2,359 +/- 860 kcal/day). Accuracy of individual DLW and I-B TDEE values was estimated from the correlations of TDEE with fat-free mass (FFM) or total weight (body wt + load). The DLW and I-B estimates of TDEE differed by -12.0 to 15.2% but provided comparable estimates of group mean TDEE (DLW = 19.07 +/- 2.37 MJ/day or 4,558 +/- 566 kcal/day; I-B = 19.41 +/- 3.72 MJ/day or 4,639 +/- 889 kcal/day; P > 0.05). The DLW TDEE was correlated with both FFM (r(2) = 0.89, P < 0.01, power = 0.95) and total weight (r(2) = 0.95, P < 0.01, power = 0.99), whereas I-B TDEE was correlated only with total weight (r(2) = 0.75, P < 0.03, power = 0.81). Under adverse field conditions the DLW method provided individual TDEE estimates that were probably more accurate than those provided by the I-B method. C1 UNIV CHICAGO,CLIN NUTR RES CTR,CHICAGO,IL 60637. UNIV WASHINGTON,DEPT MED,SEATTLE,WA 98195. RP HOYT, RW (reprint author), USA,ENVIRONM MED RES INST,DIV ALTITUDE PHYSIOL & MED,NATICK,MA 01760, USA. NR 30 TC 27 Z9 27 U1 2 U2 3 PU AMER PHYSIOLOGICAL SOC PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 0002-9513 J9 AM J PHYSIOL JI Am. J. Physiol. PD MAR PY 1994 VL 266 IS 3 BP R966 EP R971 PN 2 PG 6 WC Physiology SC Physiology GA NF861 UT WOS:A1994NF86100095 PM 8160893 ER PT J AU HOPPER, KD HOUTS, PS TENHAVE, TR MATTHEWS, YL COLON, E HASEMAN, DB HARTZEL, J AF HOPPER, KD HOUTS, PS TENHAVE, TR MATTHEWS, YL COLON, E HASEMAN, DB HARTZEL, J TI THE EFFECT OF INFORMED CONSENT ON THE LEVEL OF ANXIETY IN PATIENTS GIVEN IV CONTRAST MATERIAL SO AMERICAN JOURNAL OF ROENTGENOLOGY LA English DT Article ID ENHANCED RADIOGRAPHY; PATIENTS ATTITUDES; NONIONIC CONTRAST; MEDIA REACTIONS; HYPOTHESIS AB OBJECTIVE. A common reason given for not obtaining informed consent before the use of IV contrast material is that the anxiety created by informing patients of potential reactions will increase the possibility of their occurring. However, the idea that this is possible is debatable, and no study of this subject has used a standardized anxiety index. Accordingly, using the State-Trait Anxiety Inventory, we assessed the anxiety level among patients about to have an IV contrast procedure and measured the effect of informing them of the risks associated with the use of contrast material. SUBJECTS AND METHODS. Approximately 2050 adult outpatients at three separate medical centers were solicited for participation in this study. Each of the 1251 patients who volunteered to participate was placed into one of six groups. The majority were patients who were awaiting the injection of either ionic or nonionic contrast material and who were or were not informed of the risks associated with the use of IV contrast material. The last two groups were generally healthy outpatients reporting for routine X-rays who were not awaiting IV contrast administration but who were informed of the risks associated with the use of ionic and nonionic contrast material. Each patient informed of the risks was asked to read a standardized consent form, and all patients completed a standardized anxiety index. RESULTS. Patients who were informed of the risks associated with IV contrast material did not have measurably increased anxiety, and they did not have an increased prevalence of adverse reactions. Indeed, the only patients who had statistically significant increased anxiety compared with the other groups were among those awaiting the injection of ionic contrast material who were not informed of the risks (p = .04). The majority (51-78%) of patients in all six groups had measurable elevated anxiety scores. CONCLUSION. We conclude that it is not justified to fail to obtain informed consent in order to avoid anxiety-induced adverse reactions to IV contrast material. The majority of patients awaiting injection of IV contrast material have measurable increased anxiety levels regardless of whether they are informed of its risks. C1 PENN STATE UNIV,DEPT BEHAV SCI,HERSHEY,PA 17033. PENN STATE UNIV,CTR BIOSTAT & EPIDEMIOL,HERSHEY,PA 17033. WALTER REED ARMY MED CTR,DEPT RADIOL,WASHINGTON,DC 20307. DARTMOUTH HITCHCOCK MED CTR,DEPT RADIOL,HANOVER,NH 03756. RP HOPPER, KD (reprint author), PENN STATE UNIV,DEPT RADIOL,POB 850,HERSHEY,PA 17033, USA. NR 20 TC 26 Z9 26 U1 0 U2 0 PU AMER ROENTGEN RAY SOC PI RESTON PA 1891 PRESTON WHITE DR, SUBSCRIPTION FULFILLMENT, RESTON, VA 22091 SN 0361-803X J9 AM J ROENTGENOL JI Am. J. Roentgenol. PD MAR PY 1994 VL 162 IS 3 BP 531 EP 535 PG 5 WC Radiology, Nuclear Medicine & Medical Imaging SC Radiology, Nuclear Medicine & Medical Imaging GA MY860 UT WOS:A1994MY86000009 PM 8109491 ER PT J AU MULLIGAN, ME AF MULLIGAN, ME TI CREDIT FOR UNPUBLISHED CASE-REPORTS SO AMERICAN JOURNAL OF ROENTGENOLOGY LA English DT Letter RP MULLIGAN, ME (reprint author), WALTER REED ARMY MED CTR,WASHINGTON,DC 20307, USA. NR 4 TC 0 Z9 0 U1 0 U2 0 PU AMER ROENTGEN RAY SOC PI RESTON PA 1891 PRESTON WHITE DR, SUBSCRIPTION FULFILLMENT, RESTON, VA 22091 SN 0361-803X J9 AM J ROENTGENOL JI Am. J. Roentgenol. PD MAR PY 1994 VL 162 IS 3 BP 727 EP 727 PG 1 WC Radiology, Nuclear Medicine & Medical Imaging SC Radiology, Nuclear Medicine & Medical Imaging GA MY860 UT WOS:A1994MY86000047 PM 8109528 ER PT J AU FEIGHNY, R BURROUS, J PUTNAK, R AF FEIGHNY, R BURROUS, J PUTNAK, R TI DENGUE TYPE-2 VIRUS ENVELOPE PROTEIN MADE USING RECOMBINANT BACULOVIRUS PROTECTS MICE AGAINST VIRUS CHALLENGE SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID MONOCLONAL-ANTIBODIES; ANTIGENIC SITES; VIRAL-PROTEINS; GLYCOPROTEIN; ENCEPHALITIS; SEQUENCE; FUSION; PH AB The gene coding for the envelope (E) glycoprotein of dengue-2 virus was cloned into baculovirus (Autographa californica nuclear polyhedrosis virus). The recombinant virus contained the entire E protein gene, preceded by 38 nucleotides from the end of the prematrix glycoprotein gene and followed by the first 83 nucleotides of nonstructural protein 1. When expressed in Spodoptera frugiperda (Sf9) cells, approximately 1 mg of recombinant E antigen was made per 10(9) cells. This antigen reacted with polyclonal, anti-dengue type-2 antibody and a dengue type-2-specific, neutralizing monoclonal antibody. BALB/c mice immunized with the recombinant antigen produced only non-neutralizing antibody against dengue-2 virus, but were partially protected against morbidity and mortality after intracranial challenge with virulent dengue-2 virus. C1 WALTER REED ARMY MED CTR,WALTER REED ARMY INST RES,DEPT VIRUS DIS,WASHINGTON,DC 20307. NR 22 TC 19 Z9 22 U1 0 U2 0 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD MAR PY 1994 VL 50 IS 3 BP 322 EP 328 PG 7 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA NE918 UT WOS:A1994NE91800006 PM 8147490 ER PT J AU KARAN, SM CROWL, F MULDOON, SM AF KARAN, SM CROWL, F MULDOON, SM TI MALIGNANT HYPERTHERMIA MASKED BY CAPNOGRAPHIC MONITORING SO ANESTHESIA AND ANALGESIA LA English DT Note ID GENETIC-HETEROGENEITY; RYANODINE RECEPTOR; SUSCEPTIBILITY; INVIVO C1 WALTER REED ARMY MED CTR,WASHINGTON,DC. RP KARAN, SM (reprint author), UNIFORMED SERV UNIV HLTH SCI,F EDWARD HERBERT SCH MED,DEPT ANESTHESIOL,4301 JONES BRIDGE RD,BETHESDA,MD 20814, USA. NR 14 TC 16 Z9 18 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0003-2999 J9 ANESTH ANALG JI Anesth. Analg. PD MAR PY 1994 VL 78 IS 3 BP 590 EP 592 PG 3 WC Anesthesiology SC Anesthesiology GA NA403 UT WOS:A1994NA40300029 PM 8109781 ER PT J AU COX, J AF COX, J TI 'NESTING' SO ANTIOCH REVIEW LA English DT Poetry RP COX, J (reprint author), US MIL ACAD,W POINT,NY 10996, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ANTIOCH REVIEW PI YELLOW SPRINGS PA BOX 148, YELLOW SPRINGS, OH 45387 SN 0003-5769 J9 ANTIOCH REV JI Antioch Rev. PD SPR PY 1994 VL 52 IS 2 BP 305 EP 305 PG 1 WC Literary Reviews SC Literature GA NN199 UT WOS:A1994NN19900022 ER PT J AU MESCHUTT, D AF MESCHUTT, D TI AMERICAN ART + COLLECTIONS IN EUROPE SO APOLLO-THE INTERNATIONAL MAGAZINE OF THE ARTS LA English DT Letter RP MESCHUTT, D (reprint author), US MIL ACAD,WEST POINT MUSEUM,W POINT,NY 10996, USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU APOLLO MAGAZINE LTD PI LONDON PA 29 CHESHAM PLACE, LONDON, ENGLAND SW1X 8HB SN 0003-6536 J9 APOLLO JI Apollo-Int. Mag. Arts PD MAR PY 1994 VL 139 IS 385 BP 96 EP 96 PG 1 WC Art SC Art GA NA185 UT WOS:A1994NA18500023 ER PT J AU SINES, BJ TEATHER, EW HARVEY, SP WEIGAND, WA AF SINES, BJ TEATHER, EW HARVEY, SP WEIGAND, WA TI INVESTIGATION OF BIOLOGICAL REACTOR DESIGNS FOR TREATMENT OF METHANOL AND THIODIGLYCOL WASTE STREAMS SO APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY LA English DT Article; Proceedings Paper CT 15th Symposium on Biotechnology for Fuels and Chemicals CY MAY 10-14, 1993 CL COLORADO SPRINGS, CO SP US DOE, OFF ALTERNAT FUELS, US DOE, OFF IND PROC, US DOE, OFF TRANSPORTAT MAT, NATL RENEWABLE ENERGY LAB, OAK RIDGE NATL LAB, A E STALEY CO, ARCHER DANIELS MIDLAND CO, BIOENERGY INT L C, BIOTECH RESOURCES INC, COLORADO INST RES BIOTECHNOL, GENENCOR INT INC, GRAIN PROC CORP, NEW ENERGY CO INDIANA, RAPHAEL KATZEN ASSOC INT INC, SOUTH POINT ETHANOL, WEYERHAUSER CO, MICHIGAN BIOTECHNOL INST, AMER CHEM SOC, DIV BIOCHEM TECHNOL DE BIODEGRADATION; REACTOR DESIGN; SUBSTRATE INHIBITION; THIODIGLYCOL; REPEATED FED-BATCH AB Biological reactor designs for the degradation of the toxic compounds methanol and thiodiglycol are compared to determine the smallest volume. Both compounds exhibit substrate-inhibited cell growth behavior. Design equations were used to simulate a continuous stirred tank with cell recycle, continuous stirred tanks in series, and an optimized repeated fed-batch reactor. Thiodiglycol is the primary hydrolysis product of sulfur mustard (2,2'-dichlorodiethyl sulfide), commonly referred to as ''mustard gas.'' Experimental data for the growth of Alcaligenes xylosoxidans xylososxidans (SH42) on thiodiglycol was fit by an Andrews type inhibition equation, while the data and model for the growth of methanol was taken from the literature. The simulation results indicate that the repeated fed-batch reactor leads to significant volume reduction compared to the other two reactors configurations. C1 UNIV MARYLAND,DEPT CHEM & NUCL ENGN,COLLEGE PARK,MD 20742. MARYLAND BIOTECHNOL INST,CTR BIOTECHNOL MFG,ABERDEEN PROVING GROUND,MD 21010. USA,RES DEV & ENGN CTR,ABERDEEN PROVING GROUND,MD 21010. NR 11 TC 11 Z9 12 U1 0 U2 1 PU HUMANA PRESS INC PI TOTOWA PA 999 RIVERVIEW DRIVE SUITE 208, TOTOWA, NJ 07512 SN 0273-2289 J9 APPL BIOCHEM BIOTECH JI Appl. Biochem. Biotechnol. PD SPR PY 1994 VL 45-6 BP 881 EP 895 DI 10.1007/BF02941857 PG 15 WC Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology SC Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology GA NJ697 UT WOS:A1994NJ69700076 ER PT J AU LEADER, JJ AF LEADER, JJ TI THE NORMS OF POWERS OF MATRICES WITH UNIT SPECTRAL-RADIUS SO APPLIED MATHEMATICS LETTERS LA English DT Article DE ITERATION; MATRIX NORM; POWER METHOD AB We show that the norm of the powers of a matrix with unit spectral radius which is not of bounded type grows as 0(n(p-1)), where p is the order of the largest nonlinear divisor of the matrix associated with a unit eigenvalue. RP LEADER, JJ (reprint author), US MIL ACAD,DEPT MATH SCI,W POINT,NY 10996, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0893-9659 J9 APPL MATH LETT JI Appl. Math. Lett. PD MAR PY 1994 VL 7 IS 2 BP 15 EP 17 DI 10.1016/0893-9659(94)90023-X PG 3 WC Mathematics, Applied SC Mathematics GA NA514 UT WOS:A1994NA51400004 ER PT J AU PICANO, J KLUSMAN, L AF PICANO, J KLUSMAN, L TI INTERACTIVE EFFECTS OF EDUCATION AND DISEASE PROGRESSION ON NEUROPSYCHOLOGICAL IMPAIRMENT IN ASYMPTOMATIC HIV-SEROPOSITIVE MALES - AN EMPIRICAL-EVALUATION OF THRESHOLD THEORY SO ARCHIVES OF CLINICAL NEUROPSYCHOLOGY LA English DT Meeting Abstract C1 VET ADM OUTPATIENT CLIN,MARTINEZ,CA 94553. WALTER REED ARMY MED CTR,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0887-6177 J9 ARCH CLIN NEUROPSYCH JI Arch. Clin. Neuropsychol. PD MAR-APR PY 1994 VL 9 IS 2 BP 173 EP 173 PG 1 WC Psychology, Clinical; Psychology SC Psychology GA NM848 UT WOS:A1994NM84800115 ER PT J AU KRUEGER, RR MORALES, RB SMITH, RE SLINEY, DH CHONG, LP AF KRUEGER, RR MORALES, RB SMITH, RE SLINEY, DH CHONG, LP TI NEW STROBOSCOPIC LIGHT-SOURCE FOR INTRAOPERATIVE RETINAL FLUORESCEIN ANGIOGRAPHY SO ARCHIVES OF OPHTHALMOLOGY LA English DT Article AB We tested a new stroboscopic light source for intraoperative fluorescein angiography. A pulsed xenon light source and narrow-band interference filters are coupled to a 20-gauge endoilluminator and a 35-mm camera mounted on a surgical microscope. The system was tested with good success in a patient undergoing penetrating keratoplasty. An 18- to 22-muJ flash of 2 milliseconds' duration is achieved, which is well below the safety threshold level. This new stroboscopic light source provides a flash of sufficient light intensity to perform high-resolution, high-contrast fluorescein angiography during operations for the removal of opacified media. C1 UNIV SO CALIF,DOHENY EYE INST,1450 SAN PABLO ST,LOS ANGELES,CA 90033. USA,ENVIRONM HYG AGCY,DIV LASER MICROWAVE,ABERDEEN PROVING GROUND,MD 21010. UNIV SO CALIF,SCH MED,DEPT OPHTHALMOL,LOS ANGELES,CA 90033. FU NEI NIH HHS [EY03040] NR 11 TC 1 Z9 1 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0003-9950 J9 ARCH OPHTHALMOL-CHIC JI Arch. Ophthalmol. PD MAR PY 1994 VL 112 IS 3 BP 420 EP 422 PG 3 WC Ophthalmology SC Ophthalmology GA NB947 UT WOS:A1994NB94700034 PM 8129671 ER PT J AU GALBICKA, G AF GALBICKA, G TI MOVING BEYOND SCHEDULES AND RATE - A NEW TRAJECTORY SO BEHAVIORAL AND BRAIN SCIENCES LA English DT Discussion RP GALBICKA, G (reprint author), WALTER REED ARMY INST RES,DEPT MED NEUROSCI,WASHINGTON,DC 20307, USA. NR 5 TC 0 Z9 0 U1 0 U2 0 PU CAMBRIDGE UNIV PRESS PI NEW YORK PA 40 WEST 20TH STREET, NEW YORK, NY 10011-4211 SN 0140-525X J9 BEHAV BRAIN SCI JI Behav. Brain Sci. PD MAR PY 1994 VL 17 IS 1 BP 139 EP 140 PG 2 WC Psychology, Biological; Behavioral Sciences; Neurosciences SC Psychology; Behavioral Sciences; Neurosciences & Neurology GA NE987 UT WOS:A1994NE98700067 ER PT J AU TUNICK, A RACHELE, H HANSEN, FV HOWELL, TA STEINER, JL SCHNEIDER, AD EVETT, SR AF TUNICK, A RACHELE, H HANSEN, FV HOWELL, TA STEINER, JL SCHNEIDER, AD EVETT, SR TI REBAL-92 - A COOPERATIVE RADIATION AND ENERGY-BALANCE FIELD-STUDY FOR IMAGERY AND ELECTROMAGNETIC PROPAGATION SO BULLETIN OF THE AMERICAN METEOROLOGICAL SOCIETY LA English DT Article ID EVAPOTRANSPIRATION AB The surface energy balance directly affects vertical gradients in temperature and specific humidity within the atmospheric surface layer, and these gradients influence optical turbulence. This study was conducted to improve current understanding of the partitioning of energy at the ground surface of a bare soil field and its influence on the character and intensity of optical turbulence as represented by the refractive index structure parameter, C-n(2), and to improve micrometeorological models of the surface energy balance. The field study entitled ''Radiation Energy Balance Experiment for Imagery and Electromagnetic Propagation'' was conducted by the United States Army Atmospheric Sciences Laboratory and the United States Department of Agriculture Agricultural Research Service, at Bushland, Texas, during May and July 1992. The following were collected: diurnal radiation; evaporation (directly measured by large weighing lysimeters); five-level micrometeorological profiles of wind speed, air temperature, and relative humidity; soil temperature and volumetric water content; soil heat flux; optical turbulence (scintillometer); and near- and far-field infrared imager data over wet and dry bare soil for clear and cloudy sky conditions. Initial results from the modeling efforts indicate excellent agreement between measured and modeled values of radiation/energy balance fluxes and C(n)-2, for one day. Future model evaluation will extend over the wide range of conditions encountered during the field study. C1 USDA ARS, CONSERVAT & PROD RES LABS, BUSHLAND, TX 79012 USA. RP USA, RES LAB, BATTLEFIELD ENVIRONM DIRECTORATE, WHITE SANDS MISSILE RANGE, NM 88002 USA. NR 21 TC 9 Z9 9 U1 0 U2 1 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 USA SN 0003-0007 EI 1520-0477 J9 B AM METEOROL SOC JI Bull. Amer. Meteorol. Soc. PD MAR PY 1994 VL 75 IS 3 BP 421 EP 430 DI 10.1175/1520-0477(1994)075<0421:RCRAEB>2.0.CO;2 PG 10 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA NC607 UT WOS:A1994NC60700005 ER PT J AU KALVASS, PE AF KALVASS, PE TI THE EFFECT OF DIFFERENT HARVEST METHODS ON SEA PALM (POSTELSIA-PALMAEFORMIS) SPOROPHYLL GROWTH SO CALIFORNIA FISH AND GAME LA English DT Article AB Sea palm (Postelsia palmaeformis) is an erect annual brown alga occurring along the central and northern coasts of California in high intertidal areas subject to heavy wave shock. Presently, there is no restriction on the amount or method by which sea palm can be commercially harvested. In spring 1989, we initiated a study to compare the effects of three different harvest methods on several growth and development parameters. A factorial experimental design was chosen to examine sporophyll (blade) growth under the three treatments over a 4 month period. Treatments included blade cut in which only blades are taken, branch cut in which the rounded portion of the sporphyll is also removed, and stipe cut in which the the meristem and fruiting portion of the sporophyte is taken, as well as a control group. Monthly incremental blade growth was significantly different among treatments (P < 0.000), with the blade cut group exhibiting the fastest growth rate. Mean blade length increased 7.5 times in two months from the start of the experiment for the blade cut group, compared to a 17 percent increase for the control group for the same time period. We conclude that a harvest method similar to the blade cut treatment would have the benefit of allowing multiple yields of sporophylls in a season, ensure spore production, and reduce aesthetic degradation in comparison to the other harvest methods examined. RP KALVASS, PE (reprint author), CALIF DEPT FISH & GAME,DIV MARINE RESOURCES,19160 S HARBOR DR,FT BRAGG,CA 95437, USA. NR 0 TC 2 Z9 2 U1 1 U2 2 PU CALIF FISH AND GAME EDITOR PI SACRAMENTO PA 1416 NINTH ST, SACRAMENTO, CA 95814 SN 0008-1078 J9 CALIF FISH GAME JI Calif. Fish Game PD SPR PY 1994 VL 80 IS 2 BP 57 EP 67 PG 11 WC Fisheries; Zoology SC Fisheries; Zoology GA QH887 UT WOS:A1994QH88700002 ER PT J AU BRAWLEY, OW FORD, LG THOMPSON, I PERLMAN, JA KRAMER, BS AF BRAWLEY, OW FORD, LG THOMPSON, I PERLMAN, JA KRAMER, BS TI 5-ALPHA-REDUCTASE INHIBITION AND PROSTATE-CANCER PREVENTION SO CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION LA English DT Review ID MALE PSEUDOHERMAPHRODITISM; FINASTERIDE MK-906; ANDROGEN RECEPTOR; CARCINOMA; SERUM; ADENOCARCINOMA; TESTOSTERONE; MEN; DIHYDROTESTOSTERONE; CASTRATION AB Studies of prostate biology support the concept that dihydrotestosterone is the principal androgen responsible for normal and hyperplastic growth of the prostate gland. Cancer is a process of malignant transformation evolving over time, involving cellular growth and division. Therefore, an altered endocrine state, such as suppression of dihydrotestosterone activity, may have an impact on prostate cells inhibiting carcinogenic transformation. In vitro and in vivo preclinical observations support this hypothesis. A placebo-controlled randomized trial using finasteride, an inhibitor of the enzyme that converts testosterone to dihydrotestosterone, is planned. The endpoint of this trial will be reduction of prostate cancer incidence. C1 BROOKE ARMY MED CTR,DEPT SURG,RADIOL SERV,FT SAM HOUSTON,TX 78234. RP BRAWLEY, OW (reprint author), NCI,DIV CANC PREVENT & CONTROL,COMMUNITY ONCOL & REHABIL BRANCH,EPN,BETHESDA,MD 20892, USA. NR 59 TC 64 Z9 65 U1 0 U2 0 PU AMER ASSOC CANCER RESEARCH PI PHILADELPHIA PA PUBLIC LEDGER BLDG, SUITE 816, 150 S. INDEPENDENCE MALL W., PHILADELPHIA, PA 19106 SN 1055-9965 J9 CANCER EPIDEM BIOMAR JI Cancer Epidemiol. Biomarkers Prev. PD MAR PY 1994 VL 3 IS 2 BP 177 EP 182 PG 6 WC Oncology; Public, Environmental & Occupational Health SC Oncology; Public, Environmental & Occupational Health GA NA344 UT WOS:A1994NA34400014 PM 8049641 ER PT J AU CARDELLO, AV AF CARDELLO, AV TI DOWNSIZING AND OTHER REAL-LIFE ISSUES SO CEREAL FOODS WORLD LA English DT Editorial Material RP CARDELLO, AV (reprint author), USA,NATICK & RES DEV & ENGN CTR,NATICK,MA 01760, USA. NR 3 TC 1 Z9 1 U1 0 U2 0 PU AMER ASSOC CEREAL CHEMISTS PI ST PAUL PA 3340 PILOT KNOB RD, ST PAUL, MN 55121-2097 SN 0146-6283 J9 CEREAL FOOD WORLD JI Cereal Foods World PD MAR PY 1994 VL 39 IS 3 BP 184 EP & PG 0 WC Food Science & Technology SC Food Science & Technology GA NE581 UT WOS:A1994NE58100007 ER PT J AU ROACH, JM HURWITZ, KM ARGYROS, GJ ELIASSON, AH PHILLIPS, YY AF ROACH, JM HURWITZ, KM ARGYROS, GJ ELIASSON, AH PHILLIPS, YY TI EUCAPNIC VOLUNTARY HYPERVENTILATION AS A BRONCHOPROVOCATION TECHNIQUE - COMPARISON WITH METHACHOLINE INHALATION IN ASTHMATICS SO CHEST LA English DT Article ID COLD AIR; BRONCHIAL HYPERRESPONSIVENESS; ISOCAPNIC HYPERVENTILATION; RESPONSIVENESS; CHALLENGE; REACTIVITY; HISTAMINE; SYMPTOMS; ADULTS; ATOPY AB Methacholine inhalation challenge (MIC) is probably the most widely used and best standardized test for nonspecific bronchoprovocation challenge (BPC). There has been increasing interest in developing ''physical'' stimuli such as eucapnic voluntary hyperventilation (EVH) with dry gas to assess airway hyperreactivity (AHR), because of inherent problems with using a pharmacologic agent in epidemiologic surveys. To our knowledge, no studies exist that compare MIC with EVH in known asthmatics. We conducted a prospective, randomized, crossover trial with a group of subjects (n = 16) who met the American Thoracic Society definition of asthma with these objectives: (1) to compare the sensitivity of EVH with MIC; (2) to compare the quantitative response of one test with the response to the other challenge; and (3) to correlate the response of both tests with symptoms, serum IgE levels, and serum eosinophil counts. We found that (1) EVH was positive in 75 percent of cases and MIC was positive in 81 percent of cases; one subject reacted to EVH but not to MIC and vice-versa. (2) The quantitative response to one test correlated with the response to the other test (r = - 0.60, p = 0.01). (3) There was a correlation between severity of asthma symptoms and the response to EVH (r = 0.62; p = 0.01), but not to MIC. (4) Response to MIC (log PD20), but not EVH, correlated with serum IgE level (r = - 0.53, p = 0.04). We suggest that EVH may be used for the initial assessment of AHR in the evaluation of asthma. Eucapnic voluntary hyperventilation is a sensitive measure of AHR and it correlates well with symptoms. Furthermore, though these points were not addressed in our study, it is more physiologic than MIC, and it is easy and less expensive to perform. C1 WALTER REED ARMY MED CTR,DEPT MED,PULM & CRIT CARE MED SERV,WASHINGTON,DC 20307. UNIFORMED SERV UNIV HLTH SCI,BETHESDA,MD 20814. NR 35 TC 11 Z9 11 U1 0 U2 0 PU AMER COLL CHEST PHYSICIANS PI NORTHBROOK PA 3300 DUNDEE ROAD, NORTHBROOK, IL 60062-2348 SN 0012-3692 J9 CHEST JI Chest PD MAR PY 1994 VL 105 IS 3 BP 667 EP 672 DI 10.1378/chest.105.3.667 PG 6 WC Critical Care Medicine; Respiratory System SC General & Internal Medicine; Respiratory System GA NA618 UT WOS:A1994NA61800009 PM 8131523 ER PT J AU PREWITT, KC SMOLIN, MR COSTER, TS VERNALIS, MN BUNDA, B WORTHAM, DC AF PREWITT, KC SMOLIN, MR COSTER, TS VERNALIS, MN BUNDA, B WORTHAM, DC TI CORONARY-ARTERY FISTULA DIAGNOSED BY TRANSESOPHAGEAL ECHOCARDIOGRAPHY SO CHEST LA English DT Note ID TWO-DIMENSIONAL ECHOCARDIOGRAPHY AB Coronary artery fistulas have been traditionally diagnosed by angiography. This report describes a congenital and a traumatic coronary artery fistula diagnosed by transesophageal echocardiography. Transesophageal echocardiography was superior to transthoracic echocardiography in both cases and to angiography in one case. Transesophageal echocardiography may now be the procedure of choice in diagnosing coronary fistula. RP PREWITT, KC (reprint author), WALTER REED ARMY MED CTR,SERV CARDIOL,WASHINGTON,DC 20307, USA. NR 9 TC 12 Z9 12 U1 0 U2 0 PU AMER COLL CHEST PHYSICIANS PI NORTHBROOK PA 3300 DUNDEE ROAD, NORTHBROOK, IL 60062-2348 SN 0012-3692 J9 CHEST JI Chest PD MAR PY 1994 VL 105 IS 3 BP 959 EP 961 DI 10.1378/chest.105.3.959 PG 3 WC Critical Care Medicine; Respiratory System SC General & Internal Medicine; Respiratory System GA NA618 UT WOS:A1994NA61800071 PM 8131580 ER PT J AU BEYER, HF AF BEYER, HF TI JANUARY COVER PHOTO IS MISLEADING SO CIVIL ENGINEERING LA English DT Letter RP BEYER, HF (reprint author), USA,KANSAS CITY,MO, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ASCE-AMER SOC CIVIL ENGINEERS PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2398 SN 0885-7024 J9 CIVIL ENG JI Civil Eng. PD MAR PY 1994 VL 64 IS 3 BP 36 EP 36 PG 1 WC Engineering, Civil SC Engineering GA MZ040 UT WOS:A1994MZ04000013 ER PT J AU HAWLEY, SC AF HAWLEY, SC TI BARKSDALE MISSISSIPPI BRIGADE AT FREDERICKSBURG SO CIVIL WAR HISTORY LA English DT Article RP HAWLEY, SC (reprint author), US MIL ACAD,W POINT,NY 10996, USA. NR 29 TC 0 Z9 0 U1 0 U2 0 PU KENT STATE UNIV PRESS PI KENT PA KENT, OH 44242 SN 0009-8078 J9 CIVIL WAR HIST JI Civil War Hist. PD MAR PY 1994 VL 40 IS 1 BP 5 EP 24 PG 20 WC History SC History GA NA324 UT WOS:A1994NA32400001 ER PT J AU ARANA, BA NAVIN, TR ARANA, FE BERMAN, JD ROSENKAIMER, F AF ARANA, BA NAVIN, TR ARANA, FE BERMAN, JD ROSENKAIMER, F TI EFFICACY OF A SHORT-COURSE (10 DAYS) OF HIGH-DOSE MEGLUMINE ANTIMONATE WITH OR WITHOUT INTERFERON-GAMMA IN TREATING CUTANEOUS LEISHMANIASIS IN GUATEMALA SO CLINICAL INFECTIOUS DISEASES LA English DT Article ID SODIUM STIBOGLUCONATE PENTOSTAM; CONTROLLED CLINICAL-TRIAL; KETOCONAZOLE AB Sixty-six Guatemalan men with parasitologically confirmed cutaneous leishmaniasis, due most commonly to Leishmania braziliensis, were randomly assigned to receive one of three treatment regimens: meglumine antimonate (meglumine) for 20 days; meglumine for 10 days; and meglumine for 10 days plus alternate-day injections of interferon-gamma. In each group, meglumine was given intravenously as 20 mg of antimony/(kg of body weight.d). All treatment regimens were associated with similar response rates: the lesions of 19 (90%) of 21 patients who received meglumine for 20 days, 18 (90%) of 20 patients who received meglumine for 10 days, and all 22 patients who received meglumine plus interferon-gamma were completely reepithelialized by 13 weeks. In addition, for patients receiving all treatment regimens, test-of-cure cultures for Leishmania were negative and reactivation of lesions did not occur during 12 months of followup. The high efficacy of our 10-day course of meglumine indicates that the currently recommended duration of 20 days may be unnecessary for infections caused by L. braziliensis and suggests that a 10-day course of high-dose antimony should be tested as therapy for cutaneous leishmaniasis in other geographic areas. C1 CTR DIS CONTROL & PREVENT,NATL CTR INFECT DIS,DIV PARASIT DIS,ATLANTA,GA 30033. MED ENTOMOL RES & TRAINING UNIT,GUATEMALA CITY,GUATEMALA. WALTER REED ARMY INST RES,WASHINGTON,DC. BOEHRINGER INGELHEIM KG,W-6507 INGELHEIM,GERMANY. NR 9 TC 37 Z9 37 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 1058-4838 J9 CLIN INFECT DIS JI Clin. Infect. Dis. PD MAR PY 1994 VL 18 IS 3 BP 381 EP 384 PG 4 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA NB320 UT WOS:A1994NB32000018 PM 8011819 ER PT J AU MARIN, R BRYANT, PR ENG, GD AF MARIN, R BRYANT, PR ENG, GD TI LUMBOSACRAL PLEXOPATHY TEMPORALLY RELATED TO VACCINATION SO CLINICAL PEDIATRICS LA English DT Note ID GUILLAIN-BARRE-SYNDROME; PARALYTIC POLIOMYELITIS; PERTUSSIS-VACCINE; CONJUGATE VACCINE; TETANUS; DIPHTHERIA C1 WALTER REED ARMY MED CTR,PHYS MED & REHABIL SERV,WASHINGTON,DC 20307. CHILDRENS HOSP,NATL MED CTR,PHYS MED & REHABIL SERV,WASHINGTON,DC 20010. RP MARIN, R (reprint author), USA,HOSP GEN 2,CMR-402,BOX 474,APO,AE 09180, USA. NR 17 TC 1 Z9 1 U1 0 U2 0 PU WESTMINSTER PUBL INC PI GLEN HEAD PA 708 GLEN COVE AVE, GLEN HEAD, NY 11545 SN 0009-9228 J9 CLIN PEDIATR JI Clin. Pediatr. PD MAR PY 1994 VL 33 IS 3 BP 175 EP 177 DI 10.1177/000992289403300312 PG 3 WC Pediatrics SC Pediatrics GA NC215 UT WOS:A1994NC21500012 PM 8194297 ER PT J AU LIBSON, E MAPP, E DACHMAN, AH AF LIBSON, E MAPP, E DACHMAN, AH TI HODGKINS-DISEASE OF THE GASTROINTESTINAL-TRACT SO CLINICAL RADIOLOGY LA English DT Article ID LYMPHOMAS AB Hodgkin's disease (HD) is rarely considered in the differential diagnosis of gastrointestinal (GI) disorders. We report eight cases of GI HD. The patients, ages 16-64, all with stage IV disease of varied histologic subtypes and GI symptoms including pain, upper or lower GI bleeding and/or obstruction. There was diffuse gastric fold thickening in one case, a large submucosal mass along the proximal greater curvature in another case, and a large ulcerating mass along the lesser curvature in the third case. Tow cases of jejunal disease manifested as either a short or long segment of luminal narrowing with prominent mucosal nodularity. Another case exhibited a short area of complete mucosal destruction, irregular cavitation and intraluminal filling defect. In one additional case there was diffuse jejunal nodularity. Colonic involvement (two cases) presented as a solitary polypoid mass in transverse colon in one patient and severe narrowing of the descending colon with adjacent mesenteric mass on CT in another. We conclude that although rare in Hodgkin's disease, GI involvement should be considered, particularly in patients with stage IV disease. C1 THOMAS JEFFERSON UNIV,JEFFERSON MED COLL,DEPT RADIOL,PHILADELPHIA,PA 19107. THOMAS JEFFERSON UNIV HOSP,PHILADELPHIA,PA. UNIFORMED SERV UNIV HLTH SCI,SCH MED,DEPT RADIOL NUCL MED,BETHESDA,MD 20814. WALTER REED ARMY MED CTR,WASHINGTON,DC. RP LIBSON, E (reprint author), HADASSAH UNIV HOSP,DEPT RADIOL,POB 12000,JERUSALEM,ISRAEL. NR 22 TC 17 Z9 18 U1 0 U2 0 PU BLACKWELL SCIENCE LTD PI OXFORD PA OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL SN 0009-9260 J9 CLIN RADIOL JI Clin. Radiol. PD MAR PY 1994 VL 49 IS 3 BP 166 EP 169 DI 10.1016/S0009-9260(05)81768-4 PG 4 WC Radiology, Nuclear Medicine & Medical Imaging SC Radiology, Nuclear Medicine & Medical Imaging GA NA101 UT WOS:A1994NA10100003 PM 8143404 ER PT J AU RASZKA, WV SKILLMAN, LP MCEVOY, PL AF RASZKA, WV SKILLMAN, LP MCEVOY, PL TI IN-VITRO SUSCEPTIBILITY OF CLINICAL ISOLATES OF MYCOBACTERIUM-AVIUM AND MYCOBACTERIUM-INTRACELLULARE TO FOLATE ANTAGONISTS SO DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE LA English DT Note ID ACQUIRED-IMMUNODEFICIENCY-SYNDROME; TRIMETHOPRIM-SULFAMETHOXAZOLE; NONTUBERCULOUS MYCOBACTERIA; COMPLEX; INFECTION AB An agar dilution method against trimethoprim, sulfamethoxazole, sulfisoxazole, and trimethoprim-sulfamethoxazole was used to test clinical isolates of Mycobacterium intracellulare (MI) and M. avium (MA) from both HIV-infected and noninfected patients. MI and MA isolates demonstrated similar susceptibility data and were inhibited by concentrations of sulfamethoxazole achievable in serum.- C1 WALTER REED ARMY MED CTR,DEPT PEDIAT,WASHINGTON,DC 20307. UNIFORMED SERV UNIV HLTH SCI,DEPT PEDIAT,BETHESDA,MD 20814. WALTER REED ARMY MED CTR,DEPT PATHOL,WASHINGTON,DC 20307. NR 13 TC 4 Z9 4 U1 0 U2 0 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0732-8893 J9 DIAGN MICR INFEC DIS JI Diagn. Microbiol. Infect. Dis. PD MAR PY 1994 VL 18 IS 3 BP 201 EP 204 DI 10.1016/0732-8893(94)90092-2 PG 4 WC Infectious Diseases; Microbiology SC Infectious Diseases; Microbiology GA NT990 UT WOS:A1994NT99000012 PM 7924214 ER PT J AU GAYDOS, JC LUZ, GA AF GAYDOS, JC LUZ, GA TI MILITARY PARTICIPATION IN EMERGENCY HUMANITARIAN ASSISTANCE SO DISASTERS LA English DT Article AB Military forces of the United States and other countries possess training, equipment and capabilities that are suited for work in disaster preparedness and assistance. Information on the use of military units in domestic and foreign disaster-related efforts, particularly by United States forces in the medical area, was obtained by review of the literature and unpublished military reports, and from interviews with people who have been involved with disaster-related activities. The historical reasons for viewing United States forces as resources in disaster situations are identified. Additionally, issues and problems related to disaster preparedness and assistance in general, and more specifically, to the past and future use of military personnel for this mission are examined. The need for a defined military mission for emergency humanitarian assistance and the need for a military organizational structure to support this mission are identified. Once these two critical issues have been properly addressed, the United States military should participate in the establishment of a disaster institute for joint civilian-military disaster planning and training, in both domestic and foreign areas. C1 USA,ENVIRONM HYG AGCY,ABERDEEN PROVING GROUND,MD 21010. RP GAYDOS, JC (reprint author), UNIFORMED SERV UNIV HLTH SCI,F EDWARD HEBERT SCH MED,DEPT PREVENT MED & BIOMET,BETHESDA,MD 20814, USA. NR 34 TC 10 Z9 10 U1 0 U2 3 PU BLACKWELL PUBL LTD PI OXFORD PA 108 COWLEY RD, OXFORD, OXON, ENGLAND OX4 1JF SN 0361-3666 J9 DISASTERS JI Disasters PD MAR PY 1994 VL 18 IS 1 BP 48 EP 57 DI 10.1111/j.1467-7717.1994.tb00284.x PG 10 WC Planning & Development SC Public Administration GA MX926 UT WOS:A1994MX92600004 PM 8044641 ER PT J AU HONIG, PK WORTHAM, DC ZAMANI, K CANTILENA, LR AF HONIG, PK WORTHAM, DC ZAMANI, K CANTILENA, LR TI COMPARISON OF THE EFFECT OF THE MACROLIDE ANTIBIOTICS ERYTHROMYCIN, CLARITHROMYCIN AND AZITHROMYCIN ON TERFENADINE STEADY-STATE PHARMACOKINETICS AND ELECTROCARDIOGRAPHIC PARAMETERS SO DRUG INVESTIGATION LA English DT Article ID LONG QT SYNDROME; ANTIMICROBIAL ACTIVITY; CYTOCHROME-P-450; QUINIDINE; EFFICACY AB Terfenadine is a nonsedating histamine H-1-antagonist that, when given with ketoconazole, results in accumulation of parent terfenadine and altered cardiac repolarisation in susceptible individuals. This prospective cohort study, designed to assess macrolide effects on terfenadine pharmacokinetics and electrocardiogram (ECG) parameters, evaluated 18 healthy male and female volunteers who received terfenadine to steady-state. Equal numbers (6) were randomised to receive either erythromycin, clarithromycin or azithromycin at recommended doses while continuing terfenadine. Macrolide monotherapy effects on the ECG were also investigated. Pharmacokinetic profiles for terfenadine were performed before and after the addition of macrolide therapy, and ECGs were obtained at baseline and predose on days of blood sampling. Erythromycin and clarithromycin significantly affected the pharmacokinetics of terfenadine. Three of 6 volunteers receiving erythromycin and 4 of 6 receiving clarithromycin demonstrated accumulation of quantifiable unmetabolised terfenadine that was associated with altered cardiac repolarisation. Azithromycin had no effect on terfenadine pharmacokinetics or cardiac pharmacodynamics. C1 UNIFORMED SERV UNIV HLTH SCI,DEPT PHARMACOL,DIV CLIN PHARMACOL,4301 JONES BRIDGE RD,BETHESDA,MD 20814. UNIFORMED SERV UNIV HLTH SCI,DEPT MED,BETHESDA,MD 20814. WALTER REED ARMY MED CTR,DIV CARDIOL,WASHINGTON,DC 20307. US FDA,ROCKVILLE,MD 20857. RI Zamani, Kaveh/A-9182-2011 NR 27 TC 73 Z9 73 U1 0 U2 0 PU ADIS INTERNATIONAL LTD PI AUCKLAND PA 41 CENTORIAN DR, PRIVATE BAG 65901, MAIRANGI BAY, AUCKLAND 10, NEW ZEALAND SN 0114-2402 J9 DRUG INVEST PD MAR PY 1994 VL 7 IS 3 BP 148 EP 156 PG 9 WC Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA NB881 UT WOS:A1994NB88100005 ER PT J AU PALAZZO, AJ AF PALAZZO, AJ TI PROMOTING LATE-FALL ESTABLISHMENT OF TALL FESCUE WITH ARTIFICIAL SOIL COVERS TO MINIMIZE SOIL-EROSION SO ENVIRONMENTAL GEOCHEMISTRY AND HEALTH LA English DT Article DE TURFGRASS; SEEDLING ESTABLISHMENT; ARTIFICIAL SOIL COVER; SOIL EROSION AB Frequently, turfgrass seedings have been sown in the late fall, which usually results in a poor vegetative stand and the possibility of soil erosion the following spring. This study evaluates the effects of a spun-bonded polyester soil cover placed over a late-fall seeding on subsequent seedling growth and overwintering. Clemfine, Mustang, Rebel, and Rebel II cultivars of tall fescue (Festuca arundinacea Schreb.) were sown on a silt loam soil in late fall (on 17 October in 1989 and 19 October in 1990) and allowed to grow with and without a soil cover until June. In the spring the temperature under the soil cover was greater than 2-degrees-C warmer than the uncovered soil from mid-April through May. Over the winter, leaf and root weights showed no detrimental effects from being under the cover. Individual cultivars grown under the cover produced 2 to 11 times greater leaf yields and 38 to 270% better stand establishment than those sown on the exposed soil. However, plant winter injury was observed under the soil cover in small soil depressions which accumulated water originating from thawing. All cultivars had similar amounts of growth under the cover. However, leaf yields for Rebel were 30-55% less than the other cultivars when grown under the cover and this was probably related to a low seed germination rate. The covers also promoted weed growth, which comprised from 34-65% of total leaf weights and was found to be negatively correlated (r = -0.66) to the yields of the sown grass. The soil cover was found to be beneficial to improving the success of seedling establishment of late seedings of tall fescue in cold areas. RP PALAZZO, AJ (reprint author), USA,COLD REG RES & ENGN LAB,GEOCHEM SCI BRANCH,72 LYME RD,HANOVER,NH 03755, USA. NR 0 TC 1 Z9 1 U1 0 U2 0 PU CHAPMAN HALL LTD PI LONDON PA 2-6 BOUNDARY ROW, LONDON, ENGLAND SE1 8HN SN 0269-4042 J9 ENVIRON GEOCHEM HLTH JI Environ. Geochem. Health PD MAR PY 1994 VL 16 IS 1 BP 3 EP 7 DI 10.1007/BF00149587 PG 5 WC Engineering, Environmental; Environmental Sciences; Public, Environmental & Occupational Health; Water Resources SC Engineering; Environmental Sciences & Ecology; Public, Environmental & Occupational Health; Water Resources GA NP458 UT WOS:A1994NP45800001 PM 24198171 ER PT J AU BAKERFULCO, CJ FULCO, CS HOYT, RW CYMERMAN, A AF BAKERFULCO, CJ FULCO, CS HOYT, RW CYMERMAN, A TI COMPARISON OF HYDROSTATIC WEIGHING (HW) AND DUAL-ENERGY X-RAY ABSORPTIOMETRY (DEXA) BEFORE AND AFTER ALTITUDE EXPOSURE SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,ENVIRONM MED RES INST,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A298 EP A298 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19601718 ER PT J AU CARETTI, DM BAYHANSEN, LA KUHLMANN, WD AF CARETTI, DM BAYHANSEN, LA KUHLMANN, WD TI EFFECT OF SHORT-TERM EXERCISE ON STATIC VISUAL-ACUITY AND STEREOACUITY IN MALES AND FEMALES SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,EDGEWOOD ARSENAL,CTR RD&E,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 0 Z9 0 U1 0 U2 1 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A304 EP A304 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19601753 ER PT J AU CROSLAND, RD AF CROSLAND, RD TI ACTION OF REACTIVE OXYGEN INTERMEDIATES AND THEIR ANTAGONISTS ON TWICH TENSION OF SKELETAL-MUSCLE SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,MED RES INST INFECT DIS,FREDERICK,MD 21702. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A92 EP A92 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19600533 ER PT J AU DUBOSE, DA MOREHOUSE, DH OGLE, PL AF DUBOSE, DA MOREHOUSE, DH OGLE, PL TI HYPERTHERMIC EFFECTS ON PORCINE AORTIC ENDOTHELIAL-CELL (PAEC) PROSTACYCLIN (PGI2) AND THROMBOXANE (TX) SYNTHESIS SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,ENVIRONM MED RES INST,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A66 EP A66 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19600385 ER PT J AU FULCO, CS ROCK, PB TRAD, LA BEIDLEMAN, B SMITH, S MUZA, SR CYMERMAN, A AF FULCO, CS ROCK, PB TRAD, LA BEIDLEMAN, B SMITH, S MUZA, SR CYMERMAN, A TI INCREASED PHYSICAL-ACTIVITY AUGMENTS THE INCIDENCE AND SEVERITY OF ACUTE-MOUNTAIN-SICKNESS (AMS) DURING A SIMULATED ASCENT TO 4600-M SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,ENVIRONM MED RES INST,NATICK,MA 01760. NR 0 TC 2 Z9 2 U1 2 U2 2 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A298 EP A298 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19601719 ER PT J AU GABAREE, C JONES, T TULLEY, R ARCIERO, P KENEFICK, R STAAB, J WHITTLESEY, M AF GABAREE, C JONES, T TULLEY, R ARCIERO, P KENEFICK, R STAAB, J WHITTLESEY, M TI THE EFFECT OF BLOOD-LOSS ON EXERCISE HEART-RATE SO FASEB JOURNAL LA English DT Meeting Abstract C1 PENNINGTON BIOMED RES CTR,BATON ROUGE,LA 70808. USA,ENVIRONM MED RES INST,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A305 EP A305 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19601760 ER PT J AU KAMIMORI, GH MILANI, JA THORNE, DA TOKAR, TL KINNIK, WM DAVIS, HQ AF KAMIMORI, GH MILANI, JA THORNE, DA TOKAR, TL KINNIK, WM DAVIS, HQ TI COGNITIVE PERFORMANCE AND MOOD DURING EXERCISE IN MALES SO FASEB JOURNAL LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DEPT BEHAV BIOL,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A304 EP A304 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19601750 ER PT J AU KIANG, JG SMALLRIDGE, RC AF KIANG, JG SMALLRIDGE, RC TI SODIUM-CYANIDE INCREASES CYTOSOLIC-FREE CA2+ AND NA+ AND DECREASES INOSITOL TRISPHOSPHATES IN HUMAN A431 CELLS SO FASEB JOURNAL LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DEPT CLIN PHYSIOL,DIV MED,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A404 EP A404 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19602340 ER PT J AU KING, N ARSENAULT, JE WESTPHAL, KA MUTTER, SH MURPHY, TC CHAMPAGNE, C FRIEDL, KE ASKEW, EW AF KING, N ARSENAULT, JE WESTPHAL, KA MUTTER, SH MURPHY, TC CHAMPAGNE, C FRIEDL, KE ASKEW, EW TI NUTRITIONAL INTAKE OF FEMALE SOLDIERS DURING UNITED-STATES-ARMY BASIC TRAINING SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,ENVIRONM MED RES INST,NATICK,MA 01760. GEOCENTERS INC,NEWTON,MA 02159. PENNINGTON BIOMED RES CTR,BATON ROUGE,LA 70808. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A274 EP A274 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19601584 ER PT J AU KRZYCH, U BERGMANN, E AF KRZYCH, U BERGMANN, E TI TCR USAGE BY PLASMODIUM-FALCIPARUM-IMMUNE T-CELLS - MECHANISM(S) OF ANTIGEN RECOGNITION SO FASEB JOURNAL LA English DT Meeting Abstract C1 CATHOLIC UNIV AMER,DEPT BIOL,WASHINGTON,DC 20064. WALTER REED ARMY INST RES,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A240 EP A240 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19601387 ER PT J AU LOHRIG, B DERTZBAUGH, M ANDERSON, A AF LOHRIG, B DERTZBAUGH, M ANDERSON, A TI DEPLETION OF CD8+ INTRAEPITHELIAL LYMPHOCYTES BY CHOLERA-TOXIN SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,MRID,DIV APPL RES,FT DETRICK,MD 21702. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A515 EP A515 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19602979 ER PT J AU LYONS, TP MUZA, SR CYMERMAN, A DELANY, JP AF LYONS, TP MUZA, SR CYMERMAN, A DELANY, JP TI TOTAL-BODY WATER AND PLASMA-VOLUME RESPONSES TO HIGH-ALTITUDE ACCLIMATIZATION AND DEACCLIMATIZATION SO FASEB JOURNAL LA English DT Meeting Abstract C1 PENNINGTON BIOMED RES CTR,BATON ROUGE,LA 70808. USA,ENVIRONM MED RES INST,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A298 EP A298 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19601721 ER PT J AU MARTENS, ME SMITH, WJ AF MARTENS, ME SMITH, WJ TI MECHANISMS OF SULFUR MUSTARD-INDUCED METABOLIC INJURY SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,MED RES INST CHEM DEF,BIOCHEM PHARMACOL BRANCH,ABERDEEN PROVING GROUND,MD 21010. NR 1 TC 0 Z9 0 U1 0 U2 1 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A408 EP A408 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19602362 ER PT J AU PATTON, JF MURPHY, MM BIDWELL, TE MELLO, RP HARP, ME AF PATTON, JF MURPHY, MM BIDWELL, TE MELLO, RP HARP, ME TI EFFECTS OF CHEMICAL PROTECTIVE (CP) CLOTHING ON THE ENERGY-COST OF PROGRESSIVE TREADMILL WALKING WITH EXTERNAL LOADS SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,ENVIRONM MED RES INST,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A64 EP A64 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19600369 ER PT J AU SARIBANSOHRABY, S MIES, F FISHER, RS ABRAMOW, M AF SARIBANSOHRABY, S MIES, F FISHER, RS ABRAMOW, M TI ALDOSTERONE AND PERTUSSIS TOXIN MODULATION OF GTPASE ACTIVITY IN APICAL MEMBRANES FROM A6 EPITHELIAL-CELLS SO FASEB JOURNAL LA English DT Meeting Abstract C1 UNIV LIBRE BRUXELLES,PHYSIOPATHOL LAB,B-1050 BRUSSELS,BELGIUM. WALTER REED ARMY INST RES,DEPT NEPHROL,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A350 EP A350 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19602027 ER PT J AU SHIRAKI, K WADA, F SAGAWA, S NAGAYA, K ENDO, Y CLAYBAUGH, JR HONG, SK AF SHIRAKI, K WADA, F SAGAWA, S NAGAYA, K ENDO, Y CLAYBAUGH, JR HONG, SK TI EFFECT OF WATER TEMPERATURE ON CENTRAL VENOUS-PRESSURE AND BLOOD POOLING DURING HEAD-OUT IMMERSION IN MEN SO FASEB JOURNAL LA English DT Meeting Abstract C1 UNIV OCCUPAT & ENVIRONM HLTH,DEPT PHYSIOL,KITAKYUSHU,FUKUOKA 807,JAPAN. TRIPLER ARMY MED CTR,DEPT CLIN INVEST,HONOLULU,HI 96859. SUNY BUFFALO,DEPT PHYSIOL,BUFFALO,NY 14214. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A64 EP A64 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19600368 ER PT J AU TOMASI, M DERTZBAUGH, M HUNTER, R ELSON, C AF TOMASI, M DERTZBAUGH, M HUNTER, R ELSON, C TI USE OF MULTIPLE EMULSIONS CONTAINING CHOLERA-TOXIN (CT) FOR MUCOSAL IMMUNIZATION SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,MRIID,FREDERICK,MD 21702. UNIV ALABAMA,BIRMINGHAM,AL 35294. EMORY UNIV,ATLANTA,GA 30322. NR 0 TC 2 Z9 2 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A283 EP A283 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19601630 ER PT J AU WANG, XD KIANG, JG SMALLRIDGE, RC AF WANG, XD KIANG, JG SMALLRIDGE, RC TI EXTERNAL CALCIUM-ENTRY MAY INITIATE INOSITOL 1,4,5 TRISPHOSPHATE SIGNALING PATHWAY IN FRTL-5 THYROID-CELLS SO FASEB JOURNAL LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DEPT CLIN PHYSIOL,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A18 EP A18 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19600104 ER PT J AU WESTPHAL, KA FRIEDL, KE KRAMER, TR KING, N SHARP, MA REYNOLDS, KL AF WESTPHAL, KA FRIEDL, KE KRAMER, TR KING, N SHARP, MA REYNOLDS, KL TI HEALTH AND PERFORMANCE OF FEMALE SOLDIERS DURING UNITED-STATES-ARMY BASIC TRAINING SO FASEB JOURNAL LA English DT Meeting Abstract C1 USA,ENVIRONM MED RES INST,NATICK,MA 01760. NR 0 TC 1 Z9 1 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A168 EP A168 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19600972 ER PT J AU YAMAGA, KM KIMURA, LH BROOKS, BA WEIDA, AJ ABE, LM KANESHIRO, RM AF YAMAGA, KM KIMURA, LH BROOKS, BA WEIDA, AJ ABE, LM KANESHIRO, RM TI CORRELATION OF CYTOKINE MESSENGER-RNA PRODUCTION AND ABILITY TO ACTIVATE MONOCYTES MACROPHAGES BY MURINE CHONDROCYTES SO FASEB JOURNAL LA English DT Meeting Abstract C1 UNIV HAWAII,JOHN A BURNS SCH MED,DEPT TROP MED & MED MICROBIOL,HONOLULU,HI 96822. SHRINERS HOSP CRIPPLED CHILDREN,HONOLULU UNIT,HONOLULU,HI. TRIPLER ARMY MED CTR,HONOLULU,HI 96859. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0892-6638 J9 FASEB J JI Faseb J. PD MAR PY 1994 VL 8 IS 4 BP A230 EP A230 PG 1 WC Biochemistry & Molecular Biology; Biology; Cell Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics; Cell Biology GA ND196 UT WOS:A1994ND19601327 ER PT J AU KADAKIA, SC CASSADAY, M SHAFFER, RT AF KADAKIA, SC CASSADAY, M SHAFFER, RT TI COMPARISON OF FOLEY CATHETER AS A REPLACEMENT GASTROSTOMY TUBE WITH COMMERCIAL REPLACEMENT GASTROSTOMY TUBE - A PROSPECTIVE RANDOMIZED TRIAL SO GASTROINTESTINAL ENDOSCOPY LA English DT Article ID PERCUTANEOUS ENDOSCOPIC GASTROSTOMY; SMALL-BOWEL OBSTRUCTION; DUODENAL OBSTRUCTION; MIGRATION; BUTTON; COMPLICATIONS; MORTALITY; SUCCESS AB Percutaneous endoscopic gastrostomy (PEG) provides a non-surgical alternative to long-term enteral feeding. The gastrostomy tube, however, may deteriorate, malfunction, or be accidentally expelled, requiring replacement. A commercial gastrostomy tube is commonly used for replacement. However, a commercial replacement gastrostomy tube is many times more expensive than a Foley catheter, and the two have never been compared. We compared the efficacy and safety of an all-silicone Foley catheter used as a replacement feeding gastrostomy tube with the effectiveness of a commercial replacement gastrostomy tube in 46 patients undergoing long-term enteral feedings per gastrostomy. Twenty-four patients were randomized to the Foley group and 22 patients to the commercial replacement gastrostomy tube group, The Foley catheter functioned well without need for replacement in 16 (66%) patients for 27.4 +/- 14.8 (mean +/- SD) weeks; the commercial replacement gastrostomy tube functioned in 13 (59%) patients for 24.5 +/- 13.6 weeks (p > 0.05, NS). The Foley catheter needed to be replaced because of malfunction in 8 (34%) patients and the commercial replacement gastrostomy tube in 9 (41%) patients after 21.6 +/- 11.5 weeks and 19.3 +/- 9.3 weeks, respectively (p > 0.05, NS). Neither the Foley catheter nor the commercial replacement gastrostomy tube migrated; this was the most striking finding, in contrast to case reports in the literature. Our data suggest that the Foley catheter can be safely used as a replacement gastrostomy tube; it is considerably cheaper than the commercial replacement gastrostomy tube, and its efficacy and complication rates are similar to those of the commercial replacement gastrostomy tube. RP KADAKIA, SC (reprint author), BROOKE ARMY MED CTR,DEPT MED,GASTROENTEROL SERV,FT SAM HOUSTON,TX 78234, USA. NR 29 TC 14 Z9 15 U1 0 U2 1 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0016-5107 J9 GASTROINTEST ENDOSC JI Gastrointest. Endosc. PD MAR-APR PY 1994 VL 40 IS 2 BP 188 EP 193 PN 1 PG 6 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA NF468 UT WOS:A1994NF46800012 PM 8013820 ER PT J AU PARKER, LV AF PARKER, LV TI THE EFFECTS OF GROUND-WATER SAMPLING DEVICES ON WATER-QUALITY - A LITERATURE-REVIEW SO GROUND WATER MONITORING AND REMEDIATION LA English DT Article AB This paper reviews both field and laboratory studies that tested or compared the ability of various types of sampling devices to deliver representative ground water samples. Several types of grab samplers, positive displacement devices, and suction-lift devices were evaluated. Gas-lift and inertial-lift pumps were also evaluated. This study found that most of these devices can, under certain circumstances, alter the chemistry of ground water samples. Gas-lift pumps, older types of submersible centrifugal pumps, and suction-lift devices are not recommended when sampling for sensitive constituents such as volatile organics and inorganics, or inorganics that are subject to oxidation/precipitation reactions. In general, of the devices reviewed in this paper, bladder pumps gave the best recovery of sensitive constituents. However, better performance could be achieved for several devices if improved operational guidelines were developed by additional testing, especially at lower flow rates. Clearly, further research is warranted. Future studies should focus on pumping rate, flow control mechanisms, and dedication or decontamination of sampling devices. RP PARKER, LV (reprint author), USA,COLD REG RES & ENGN LAB,72 LYME RD,HANOVER,NH 03755, USA. NR 0 TC 28 Z9 28 U1 0 U2 2 PU GROUND WATER PUBLISHING CO PI WESTERVILLE PA 601 DEMPSEY RD, WESTERVILLE, OH 43081 SN 1069-3629 J9 GROUND WATER MONIT R JI Ground Water Monit. Remediat. PD SPR PY 1994 VL 14 IS 2 BP 130 EP 141 DI 10.1111/j.1745-6592.1994.tb00108.x PG 12 WC Water Resources SC Water Resources GA NG859 UT WOS:A1994NG85900008 ER PT J AU BURKE, AP ANDERSON, D MANNAN, P RIBAS, JL LIANG, YH SMIALEK, J VIRMANI, R AF BURKE, AP ANDERSON, D MANNAN, P RIBAS, JL LIANG, YH SMIALEK, J VIRMANI, R TI SYSTEMIC LYMPHADENOPATHIC HISTOLOGY IN HUMAN IMMUNODEFICIENCY VIRUS-1-SEROPOSITIVE DRUG-ADDICTS WITHOUT APPARENT ACQUIRED-IMMUNODEFICIENCY-SYNDROME SO HUMAN PATHOLOGY LA English DT Article DE SYNCYTIAL CELLS; WARTHIN-FINKELDEY CELLS; HUMAN IMMUNODEFICIENCY VIRUS; LYMPH NODES; FOLLICULAR FRAGMENTATION ID AIDS-RELATED COMPLEX; LYMPH-NODE BIOPSY; GERMINAL-CENTERS; HOMOSEXUAL MEN; VIRUS TYPE-1; HELPER; CELLS; ARC C1 WALTER REED ARMY MED CTR,INST RES,DIV RETROVIROL,WASHINGTON,DC. HENRY M JACKSON FDN,ROCKVILLE,MD. UNIV MARYLAND,DEPT PATHOL,DIV FORENS PATHOL,BALTIMORE,MD 21201. RP BURKE, AP (reprint author), ARMED FORCES INST PATHOL,DEPT CARDIOVASC PATHOL,WASHINGTON,DC 20306, USA. NR 29 TC 25 Z9 25 U1 0 U2 0 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0046-8177 J9 HUM PATHOL JI Hum. Pathol. PD MAR PY 1994 VL 25 IS 3 BP 248 EP 256 DI 10.1016/0046-8177(94)90196-1 PG 9 WC Pathology SC Pathology GA NF072 UT WOS:A1994NF07200007 PM 8150456 ER PT J AU LOBAD, AI RODNEY, PJ MEHTA, SM TOUSLEY, BC FAUCHET, PM AF LOBAD, AI RODNEY, PJ MEHTA, SM TOUSLEY, BC FAUCHET, PM TI THE STARTING MECHANISM IN COUPLED-CAVITY MODELOCKED LASER SYSTEMS SO IEEE JOURNAL OF QUANTUM ELECTRONICS LA English DT Article ID PULSE MODE-LOCKING; NONLINEAR EXTERNAL CAVITY; ND-YLF LASER; TI-AL2O3 LASER; GENERATION AB We present what we believe to be the starting mechanism in coupled-cavity additive pulse modelocked (APM) laser systems. The etalon effect of the coupled cavity forces the main cavity to lase at two separate frequencies,thus producing short and strong mode beating ''noise bursts'' that can overcome dynamic gain saturation in large emission cross-section gain media. As a result, self-starting is possible for the NaCl:OH coupled-cavity color center laser. The dependence of the etalon effect on the cavity length detuning and its role in the dynamics of the APM process and in self-stabilized picosecond coupled-cavity lasers are discussed. The experimental observation of THz-mode beating fluctuations produced by the mode structure of a coupled-cavity NaCl:OH color center laser supports our model. C1 PRINCETON UNIV,PRINCETON,NJ 08544. US MIL ACAD,DEPT ELECT ENGN & COMP SCI,W POINT,NY 10996. US MIL ACAD,DEPT ELECT ENGN,W POINT,NY 10996. UNIV ROCHESTER,INST OPT,ROCHESTER,NY 14627. US MIL ACAD,DEPT PHYS & ASTRON,W POINT,NY 10996. AEROSP CORP,LOS ANGELES,CA 90009. RP LOBAD, AI (reprint author), UNIV ROCHESTER,LASER ENERGET LAB,250 E RIVER RD,ROCHESTER,NY 14623, USA. NR 17 TC 1 Z9 1 U1 0 U2 1 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9197 J9 IEEE J QUANTUM ELECT JI IEEE J. Quantum Electron. PD MAR PY 1994 VL 30 IS 3 BP 812 EP 817 DI 10.1109/3.286173 PG 6 WC Engineering, Electrical & Electronic; Optics; Physics, Applied SC Engineering; Optics; Physics GA NR239 UT WOS:A1994NR23900023 ER PT J AU BOUMAN, CA SHAPIRO, M AF BOUMAN, CA SHAPIRO, M TI A MULTISCALE RANDOM-FIELD MODEL FOR BAYESIAN IMAGE SEGMENTATION SO IEEE TRANSACTIONS ON IMAGE PROCESSING LA English DT Article ID GIBBS RANDOM-FIELDS; TEXTURE SEGMENTATION; STATISTICAL-ANALYSIS; AUTOREGRESSIVE PROCESSES; STOCHASTIC RELAXATION; EM ALGORITHM; CLASSIFICATION; EXTRACTION AB Many approaches to Bayesian image segmentation have used maximum a posteriori (MAP) estimation in conjunction with Markov random fields (MRF). Although this approach performs well, it has a number of disadvantages. In particular, exact MAP estimates cannot be computed, approximate MAP estimates are computationally expensive to compute, and unsupervised parameter estimation of the MRF is difficult. In this paper, we propose a new approach to Bayesian image segmentation that directly addresses these problems. The new method replaces the MRF model with a novel multiscale random field (MSRF) and replaces the MAP estimator with a sequential MAP (SMAP) estimator derived from a novel estimation criteria. Together, the proposed estimator and model result in a segmentation algorithm that is not iterative and can be computed in time proportional to MN where M is the number of classes and N is the number of pixels. We also develop a computationally efficient method for unsupervised estimation of model parameters. Simulations on synthetic images indicate that the new algorithm performs better and requires much less computation than MAP estimation using simulated annealing. The algorithm is also found to improve classification accuracy when applied to the segmentation of multispectral remotely sensed images with ground truth data. C1 USA,CONSTRUCT ENGN RES LAB,CHAMPAIGN,IL 61826. RP BOUMAN, CA (reprint author), PURDUE UNIV,SCH ELECT ENGN,W LAFAYETTE,IN 47907, USA. NR 47 TC 361 Z9 400 U1 1 U2 19 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 1057-7149 J9 IEEE T IMAGE PROCESS JI IEEE Trans. Image Process. PD MAR PY 1994 VL 3 IS 2 BP 162 EP 177 DI 10.1109/83.277898 PG 16 WC Computer Science, Artificial Intelligence; Engineering, Electrical & Electronic SC Computer Science; Engineering GA PU065 UT WOS:A1994PU06500005 PM 18291917 ER PT J AU SCHUSCHEREBA, ST BOWMAN, PD FERRANDO, RE LUND, DJ QUONG, JA VARGAS, JA AF SCHUSCHEREBA, ST BOWMAN, PD FERRANDO, RE LUND, DJ QUONG, JA VARGAS, JA TI ACCELERATED HEALING OF LASER-INJURED RABBIT RETINA BY BASIC FIBROBLAST GROWTH-FACTOR SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Article DE PHOTORECEPTOR RESCUE; ACCELERATED HEALING; BASIC FIBROBLAST GROWTH FACTOR; RETINA; LASER INJURY ID PROLIFERATION; EYE; ANTIBODY; INVIVO; REPAIR; CELLS AB Purpose. To improve the outcome of injured retina, human recombinant basic fibroblast growth factor (bFGF) was examined for its ability to accelerate healing in laser-injured New Zealand Red-rabbits. Methods. A multiline argon laser (454 to 514 nm) was used to produce lesions near subretinal hemorrhaging levels. Within 30 minutes after irradiation, eyes were intravitreally injected directly above the lesions with 10 mu l vehicle or 10 mu g of bFGF in 10 mu l of vehicle. Lesions were evaluated by funduscopy and fluorescein angiography. After 4 days of treatment, animals were killed and eyes examined histologically. Results. On subsequent days, bFGF-treated lesions were less opaque, smaller in diameter, and less leaky to fluorescein than lesions in the control eyes. Eyes treated with bFGF exhibited reduction in lesion diameter (P less than or equal to 0.001) and in the lesion periphery, decreased loss of photoreceptors (P less than or equal to 0.001), and greater numbers of pigmented epithelial cells, compared to controls. By bromodeoxyuridine incorporation, increased proliferation occurred in fibroblasts, retinal pigmented epithelial cells, and inner retinal glial cells. Conclusions. These results indicate that bFGF both accelerated ocular tissue repair and also prevented photoreceptor loss. The rescue of photoreceptors by bFGF may occur through direct action on the photoreceptors, or indirectly through effects on other cells in the retina. RP SCHUSCHEREBA, ST (reprint author), USA,MED RES DETACHMENT,WALTER REED ARMY INST RES,DEPT CELL & MOLEC BIOL,BROOKS AFB,TX 78235, USA. NR 30 TC 27 Z9 28 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD MAR PY 1994 VL 35 IS 3 BP 945 EP 954 PG 10 WC Ophthalmology SC Ophthalmology GA MZ261 UT WOS:A1994MZ26100023 PM 8125757 ER PT J AU KECK, GL MUELLER, B AF KECK, GL MUELLER, B TI OBSERVATIONS - INTENDED VS UNINTENDED MESSAGES - VIEWER PERCEPTIONS OF UNITED-STATES-ARMY TELEVISION COMMERCIALS SO JOURNAL OF ADVERTISING RESEARCH LA English DT Article C1 SAN DIEGO STATE UNIV,DEPT JOURNALISM,SAN DIEGO,CA 92182. RP KECK, GL (reprint author), US MIL ACAD,W POINT,NY 10996, USA. NR 13 TC 4 Z9 4 U1 0 U2 1 PU ADVERTISING RES FOUNDATION PI NEW YORK PA 641 LEXINGTON AVE, NEW YORK, NY 10022 SN 0021-8499 J9 J ADVERTISING RES JI J. Advert. Res. PD MAR-APR PY 1994 VL 34 IS 2 BP 70 EP 78 PG 9 WC Business; Communication SC Business & Economics; Communication GA NH288 UT WOS:A1994NH28800010 ER PT J AU JACKO, RB REED, DA AF JACKO, RB REED, DA TI A BANDED DOUBLE-RING ELECTRODYNAMIC BALANCE FOR THE SUSPENSION OF SUBMILLIMETER SIZED PARTICLES SO JOURNAL OF AEROSOL SCIENCE LA English DT Article ID AEROSOL-PARTICLE AB A banded double ring electrodynamic balance (BDRB) has been developed at Purdue University and utilized to electrodynamically suspend droplets >750 mum in diameter. This represents a three fold increase in diameter and thirty fold increase in mass from prior electrodynamic suspension devices. The balance geometry and some construction details are presented. Numeric modelling of the equations of motion is shown to be superior to the traditional Mathieu approach for determining the onset of particle stability. The charge simulation technique (CST) was used to determine the electric field within the balance environment. Results indicate that the difference between Mathieu stability and numeric calculations result from the assumption of Stoke's drag, which is necessary for the Mathieu solution. Particle Reynold's numbers for a droplet are numerically computed to be as high as 10. C1 USA,ENVIRONM HYG AGCY,ABERDEEN PROVING GROUND,MD 21010. RP JACKO, RB (reprint author), PURDUE UNIV,CIVIL ENGN BLDG,W LAFAYETTE,IN 47907, USA. NR 17 TC 3 Z9 3 U1 0 U2 2 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0021-8502 J9 J AEROSOL SCI JI J. Aerosol. Sci. PD MAR PY 1994 VL 25 IS 2 BP 289 EP 294 DI 10.1016/0021-8502(94)90080-9 PG 6 WC Engineering, Chemical; Engineering, Mechanical; Environmental Sciences; Meteorology & Atmospheric Sciences SC Engineering; Environmental Sciences & Ecology; Meteorology & Atmospheric Sciences GA NH116 UT WOS:A1994NH11600005 ER PT J AU GRUNER, E AF GRUNER, E TI FORGETTING THE GULF-WAR POW + DESERT-STORM AMERICAN CAPTIVES SO JOURNAL OF AMERICAN CULTURE LA English DT Article RP GRUNER, E (reprint author), US MIL ACAD,W POINT,NY 10996, USA. NR 6 TC 0 Z9 0 U1 0 U2 0 PU POPULAR PRESS PI BOWLING GREEN PA BOWLING GREEN STATE UNIV, BOWLING GREEN, OH 43403 SN 0191-1813 J9 J AM CULTURE JI J. Am. Cult. PD SPR PY 1994 VL 17 IS 1 BP 47 EP 51 DI 10.1111/j.1542-734X.1994.00047.x PG 5 WC Humanities, Multidisciplinary SC Arts & Humanities - Other Topics GA NF581 UT WOS:A1994NF58100008 ER PT J AU HEWITT, AD AF HEWITT, AD TI COMPARISON OF METHODS FOR SAMPLING VADOSE ZONE SOILS FOR DETERMINATION OF TRICHLOROETHYLENE SO JOURNAL OF AOAC INTERNATIONAL LA English DT Article ID VOLATILE AB This study compares 2 sampling and handling methods for the collection of soils to be analyzed for volatile organic compounds (VOCs). The currently accepted practice uses a vessel for the sole purpose of transferring and storing suspect soils from hazardous waste sites. This practice requires that the soil that is analyzed be handled at least twice: once when the vessel is filled on site and again when a subsample is removed for laboratory analysis. The sampling and handling protocol with which the current practice was compared limits sample exposure and disruption during collection and provides for sample acquisition during the field sampling exercise. The results confirm that sampling methods that limit disruption and exposure of soil samples are needed to obtain more accurate measurements of VOC concentrations in vadose zone soils. RP HEWITT, AD (reprint author), USA,COLD REG RES & ENGN LAB,72 LYME RD,HANOVER,NH 03755, USA. NR 7 TC 6 Z9 6 U1 0 U2 1 PU AOAC INTERNATIONAL PI GAITHERSBURG PA 481 NORTH FREDRICK AVE, STE 500, GAITHERSBURG, MD 20877-2504 SN 1060-3271 J9 J AOAC INT JI J. AOAC Int. PD MAR-APR PY 1994 VL 77 IS 2 BP 458 EP 463 PG 6 WC Chemistry, Analytical; Food Science & Technology SC Chemistry; Food Science & Technology GA NF078 UT WOS:A1994NF07800024 ER PT J AU PEACOCK, MD SCHENK, DA LAWRENCE, RA MORGAN, JA JENKINSON, SG AF PEACOCK, MD SCHENK, DA LAWRENCE, RA MORGAN, JA JENKINSON, SG TI ELIMINATION OF GLUTATHIONE-INDUCED PROTECTION FROM HYPERBARIC HYPEROXIA BY ACIVICIN SO JOURNAL OF APPLIED PHYSIOLOGY LA English DT Article DE GAMMA-GLUTAMYL TRANSPEPTIDASE; HYPERBARIC OXYGEN TOXICITY; RAT ID GLUTAMYL-TRANSFERASE TRANSPEPTIDASE; ISOLATED RAT HEPATOCYTES; OXYGEN-TOXICITY; SELENIUM DEFICIENCY; OXIDATIVE INJURY; EXOGENOUS GLUTATHIONE; PLASMA GLUTATHIONE; LUNG GLUTATHIONE; SMALL-INTESTINE; LYMPHOID-CELLS AB Glutathione (GSH) administered intraperitoneally significantly prolongs the time to initial seizure and survival time of rats exposed to hyperbaric hyperoxia (HBO). Acivicin is an antitumor antibiotic that is an inhibitor of gamma-glutamyl transpeptidase (GGT), an enzyme necessary for the breakdown and transport across cell membranes of GSH. To determine whether acivicin treatment alters GSH-induced protection from HBO, rats were dosed with 25 mg/kg of acivicin or vehicle 1 h before O-2 exposure at an inspired O-2 fraction at 1.0 at 4 ATA. Immediately before exposure, rats received GSH (1 mmol/kg) or vehicle. Time to seizure and time to death were recorded during exposure by direct observation. In separate groups of rats on the same dosing schedule, plasma GSH, renal GGT, and brain GGT were measured 15 min after the GSH injection without HBO exposure and 100 min after the beginning of HBO exposure. Renal GGT was decreased to 2.5% of control and brain GGT to 37% of control in the acivicin-dosed rats. Plasma GSH increased 3-fold in rats given acivicin alone, 52-fold in rats given GSH alone, and 84-fold in rats receiving both acivicin and GSH. Rats dosed with GSH alone had significantly prolonged times to seizure and death compared with all other groups. Rats dosed with GSH after receiving acivicin were not protected from HBO despite the large increase in plasma GSH that occurred in these animals. GSH treatment did not increase tissue GSH in lung, liver, or brain at 160 or 200 min of exposure. These data support the hypothesis that acivicin treatment abolishes GSH-induced protection from HBO and that elevations in plasma GSH do not protect acivicin-treated animals. C1 UNIV TEXAS,HLTH SCI CTR,BROOKE ARMY MED CTR,WILFORD HALL USAF MED CTR,LUNG METAB UNIT,SAN ANTONIO,TX. AUDIE L MURPHY VET AFFAIRS HOSP,SAN ANTONIO,TX 78284. NR 44 TC 12 Z9 12 U1 0 U2 1 PU AMER PHYSIOLOGICAL SOC PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 8750-7587 J9 J APPL PHYSIOL JI J. Appl. Physiol. PD MAR PY 1994 VL 76 IS 3 BP 1279 EP 1284 PG 6 WC Physiology; Sport Sciences SC Physiology; Sport Sciences GA NB204 UT WOS:A1994NB20400044 PM 7911799 ER PT J AU SIDELL, FR AF SIDELL, FR TI CLINICAL EFFECTS OF ORGANOPHOSPHORUS CHOLINESTERASE-INHIBITORS SO JOURNAL OF APPLIED TOXICOLOGY LA English DT Article; Proceedings Paper CT Symposium on Ocular Effects of Organophosphate Exposure CY JUN 04, 1992 CL NATL LIB MED, BETHESDA, MD SP SOC COMPARAT OPHTHALMOLOGY, ASSOC GOVT TOXICOLOGISTS HO NATL LIB MED DE CHOLINESTERASE INHIBITORS; ORGANOPHOSPHORUS COMPOUNDS; NERVE AGENTS; HUMANS; EFFECTS; TREATMENT; EYES; VISION; MIOSIS; ACUITY; SEIZURES; BREATHING ID SARIN AB Nerve agents, highly toxic organophosphorus cholinesterase inhibitors, inhibit acetylcholinesterase and cause an accumulation of acetylcholine. Clinical effects depend on the route and amount of exposure and include miosis, bronchoconstriction, excessive secretions, vomiting, seizures, and cessation of respiratory and cardiac activity. Eye effects include miosis, engorgement of ocular vessels, pain, and a decrease in light sensitivity. Therapy consists of atropine, a cholinesterase reactivator (pralidoxime), and ventilation as needed. RP SIDELL, FR (reprint author), USA,MED RES INST CHEM DEF,CHEM CASUALTY CARE OFF,ABERDEEN PROVING GROUND,MD 21014, USA. NR 17 TC 47 Z9 47 U1 1 U2 3 PU JOHN WILEY & SONS LTD PI W SUSSEX PA BAFFINS LANE CHICHESTER, W SUSSEX, ENGLAND PO19 1UD SN 0260-437X J9 J APPL TOXICOL JI J. Appl. Toxicol. PD MAR-APR PY 1994 VL 14 IS 2 BP 111 EP 113 DI 10.1002/jat.2550140212 PG 3 WC Toxicology SC Toxicology GA NG939 UT WOS:A1994NG93900009 PM 8027505 ER PT J AU MOHLER, JL WILLIAMS, BT THOMPSON, IM MARSHALL, ME AF MOHLER, JL WILLIAMS, BT THOMPSON, IM MARSHALL, ME TI COUMARIN (1,2-BENZOPYRONE) FOR THE TREATMENT OF PROSTATIC-CARCINOMA SO JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY LA English DT Article; Proceedings Paper CT Satellite Symposium of the 21st German Cancer Congress: 1, 2-Benzopyrone (Coumarin), at the 2nd Proceedings of the International-Society-of-Coumarin-Investigation CY MAR 09, 1994 CL HAMBURG, GERMANY SP INT SOC COUMARIN INVESTIGATORS DE PROSTATIC CARCINOMA; COUMARIN; IMMUNOTHERAPY ID RENAL-CELL CARCINOMA; ADVANCED MALIGNANT-MELANOMA; EXTENDED FIELD RADIATION; RADICAL PROSTATECTOMY; FOLLOW-UP; PHASE-II; CIMETIDINE; ADENOCARCINOMA; THERAPY; RADIOTHERAPY AB The unavailablility of effective treatment for metastatic hormone-refractory and clinically localized but pathologically unfavorable prostatic carcinoma warrants trial of new and promising treatments. Preliminary studies in patients with metastatic disease have shown (a) subjective but no objective responses to 100 mg coumarin and cimetidine daily; (b) objective responses in 3 of 40 patients treated with 3 g coumarin daily, all of whom had normal performance status and 1 of whom remains with three resolved bone metastases and stable prostate-specific antigen levels after 4 years; (c) toxicity only in bedridden patients. We recently initiated two multi-center trials of 1 g coumarin daily. Metastatic prostatic carcinoma patients of normal performance status were treated in a phase II trial. Patients who had been treated by radical prostatectomy, but had surgical margin, seminal vesicle or lymph node involvement or detectable prostate-specific antigen after radical prostatectomy, were randomized to coumarin or placebo. C1 BROOKE ARMY MED CTR,FT SAM HOUSTON,TX 78234. UNIV ALABAMA,MED CTR,BIRMINGHAM,AL 35294. RP MOHLER, JL (reprint author), UNIV N CAROLINA,DIV UROL,C-B 7235,CHAPEL HILL,NC 27599, USA. NR 35 TC 25 Z9 26 U1 0 U2 1 PU SPRINGER VERLAG PI NEW YORK PA 175 FIFTH AVE, NEW YORK, NY 10010 SN 0171-5216 J9 J CANCER RES CLIN JI J. Cancer Res. Clin. Oncol. PD MAR PY 1994 VL 120 SU S BP S35 EP S38 DI 10.1007/BF01377123 PG 4 WC Oncology SC Oncology GA NB889 UT WOS:A1994NB88900011 PM 8132702 ER PT J AU MCANENY, DS AF MCANENY, DS TI REGIONAL COASTAL DATABASES FOR CORPS OF ENGINEERS DISTRICTS SO JOURNAL OF COASTAL RESEARCH LA English DT Article DE COASTAL ENGINEERING; COMPUTER HINDCASTS; OCEANOGRAPHIC DATASETS; WATER WAVES; WINDS AB From a mainframe computer version in the early 1980's to today's microcomputer format, coastal databases have been recognized as important tools for support of Corps of Engineers coastal projects. The Coastal Engineering Data Retrieval System (CEDRS) takes advantage of the microcomputer environment to provide convenient access to the voluminous oceanographic datasets. CEDRS uses a regional approach, generally following Corps of Engineers District boundaries, to allow its systems to operate in the microcomputer environment using relational database techniques, and to contain a comprehensive long-term set of both hindcast and measured wind and wave data for the use of Corps coastal engineers and scientists. This presentation of the pitfalls and problems encountered in design and development of the CEDRS databases may be of benefit to other developers of this type of system. RP MCANENY, DS (reprint author), USA,COASTAL ENGN RES CTR,ENGINEER WATERWAYS EXPT STN,VICKSBURG,MS 39180, USA. NR 15 TC 2 Z9 2 U1 0 U2 1 PU COASTAL EDUCATION & RESEARCH FOUNDATION PI LAWRENCE PA 810 EAST 10TH STREET, LAWRENCE, KS 66044 SN 0749-0208 J9 J COASTAL RES JI J. Coast. Res. PD SPR PY 1994 VL 10 IS 2 BP 270 EP 277 PG 8 WC Environmental Sciences; Geography, Physical; Geosciences, Multidisciplinary SC Environmental Sciences & Ecology; Physical Geography; Geology GA NG933 UT WOS:A1994NG93300004 ER PT J AU RICCI, ER KESSLER, JR AF RICCI, ER KESSLER, JR TI APICAL SEAL OF TEETH OBTURATED BY THE LATERALLY CONDENSED GUTTA-PERCHA, THE THERMAFIL PLASTIC AND THERMAFIL METAL OBTURATOR TECHNIQUES AFTER POST SPACE PREPARATION SO JOURNAL OF ENDODONTICS LA English DT Article AB This in vitro study was conducted to determine the effect of post space preparation on teeth obturated with the Thermafil technique, both plastic and metal carriers, and the lateral condensation method. Three groups of 30 teeth each were obturated using the lateral condensation technique and the Thermafil plastic and metal techniques. Post space preparations were accomplished on the obturated groups. All specimens were submerged in India ink under a vacuum for 15 min and then soaked for an additional hour at atmospheric pressure. The teeth were decalcified and cleared to permit visualization and measurement of the extent of dye penetration. There was approximately three times more dye penetration in group 2 (plastic carrier) when compared with group 1 (lateral condensation) and group 3 (metal carrier). This was statistically significant at the 99% confidence level. C1 ADV EDUC PROGRAM GEN DENT,FT BRAGG,NC. NR 14 TC 11 Z9 11 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0099-2399 J9 J ENDODONT JI J. Endod. PD MAR PY 1994 VL 20 IS 3 BP 123 EP 126 DI 10.1016/S0099-2399(06)80056-7 PG 4 WC Dentistry, Oral Surgery & Medicine SC Dentistry, Oral Surgery & Medicine GA NA967 UT WOS:A1994NA96700005 PM 7996083 ER PT J AU PARDALOS, PM SHALLOWAY, D XUE, GL AF PARDALOS, PM SHALLOWAY, D XUE, GL TI OPTIMIZATION METHODS FOR COMPUTING GLOBAL MINIMA OF NONCONVEX POTENTIAL-ENERGY FUNCTIONS SO JOURNAL OF GLOBAL OPTIMIZATION LA English DT Article DE MOLECULAR CONFORMATION; PROTEIN FOLDING; NONCONVEX POTENTIAL FUNCTIONS; GLOBAL OPTIMIZATION; SIMULATED ANNEALING; PARALLEL ALGORITHMS ID DIFFUSION EQUATION METHOD; INCREMENTAL PULSE SEARCH; LENNARD-JONES CLUSTERS; MOLECULAR-DYNAMICS; PARTICLE SIMULATIONS; 6000 ATOMS; MINIMIZATION; ALGORITHM; MODELS; PERFORMANCE AB The minimization of potential energy functions plays an important role in the determination of ground states or stable states of certain classes of molecular clusters and proteins. In this paper we introduce some of the most commonly used potential energy functions and discuss different optimization methods used in the minimization of nonconvex potential energy functions. A very complete bibliography is also given. C1 UNIV FLORIDA,DEPT IND & SYST ENGN,GAINESVILLE,FL 32611. CORNELL UNIV,BIOCHEM MOLEC & CELL BIOL SECT,ITHACA,NY 14853. UNIV VERMONT,DEPT COMP SCI & ELECT ENGN,BURLINGTON,VT 05405. UNIV MINNESOTA,ARMY HIGH PERFORMANCE COMP RES CTR,MINNEAPOLIS,MN 55415. RI Pardalos, Panos/D-3645-2009 NR 80 TC 40 Z9 40 U1 0 U2 2 PU KLUWER ACADEMIC PUBL PI DORDRECHT PA SPUIBOULEVARD 50, PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS SN 0925-5001 J9 J GLOBAL OPTIM JI J. Glob. Optim. PD MAR PY 1994 VL 4 IS 2 BP 117 EP 133 DI 10.1007/BF01096719 PG 17 WC Operations Research & Management Science; Mathematics, Applied SC Operations Research & Management Science; Mathematics GA NA679 UT WOS:A1994NA67900002 ER PT J AU XUE, GL AF XUE, GL TI MOLECULAR-CONFORMATION ON THE CM-5 BY PARALLEL 2-LEVEL SIMULATED ANNEALING SO JOURNAL OF GLOBAL OPTIMIZATION LA English DT Article DE MOLECULAR CONFORMATION; GLOBAL OPTIMIZATION; SIMULATED ANNEALING; PARALLEL ALGORITHMS ID LENNARD-JONES CLUSTERS; OPTIMIZATION AB In this paper, we propose a new kind of simulated annealing algorithm called two-level simulated annealing for solving certain class of hard combinatorial optimization problems. This two-level simulated annealing algorithm is less likely to get stuck at a non-global minimizer than conventional simulated annealing algorithms. We also propose a parallel version of our two-level simulated annealing algorithm and discuss its efficiency. This new technique is then applied to the Molecular Conformation problem in 3 dimensional Euclidean space. Extensive computational results on Thinking Machines CM-5 are presented. With the full Lennard-Jones potential function, we were able to get satisfactory results for problems for cluster sizes as large as 100, 000. A peak rate of over 0.8 giga flop per second in 64-bit operations was sustained on a partition with 512 processing elements. To the best of our knowledge, ground states of Lennard-Jones clusters of size as large as these have never been reported before. C1 UNIV MINNESOTA,ARMY HIGH PERFORMANCE COMP RES CTR,MINNEAPOLIS,MN 55415. UNIV VERMONT,DEPT COMP SCI & ELECT ENGN,BURLINGTON,VT 05405. NR 35 TC 25 Z9 26 U1 0 U2 0 PU KLUWER ACADEMIC PUBL PI DORDRECHT PA SPUIBOULEVARD 50, PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS SN 0925-5001 J9 J GLOBAL OPTIM JI J. Glob. Optim. PD MAR PY 1994 VL 4 IS 2 BP 187 EP 208 DI 10.1007/BF01096722 PG 22 WC Operations Research & Management Science; Mathematics, Applied SC Operations Research & Management Science; Mathematics GA NA679 UT WOS:A1994NA67900005 ER PT J AU HAUGLAND, RP YOU, WM PARAGAS, VB WELLS, KS DUBOSE, DA AF HAUGLAND, RP YOU, WM PARAGAS, VB WELLS, KS DUBOSE, DA TI SIMULTANEOUS VISUALIZATION OF G-ACTIN AND F-ACTIN IN ENDOTHELIAL-CELLS SO JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY LA English DT Article DE ACTIN; ENDOTHELIAL CELLS; DNASE I; PHALLOIDIN ID MUSCLE TROPOMYOSIN POLYMERIZATION; DEOXYRIBONUCLEASE-I; DNASE-I; CELLULAR-TRANSFORMATION; CYTOSKELETON; FILAMENTS; PROTEINS; NOREPINEPHRINE; SEROTONIN; HISTAMINE AB We developed site-specific fluorescent probes that permit simultaneous microscopic observation of G- and F-actin in bovine endothelial cells. G-actin distribution was visualized with fluorescein-deoxyribonuclease I (DNAse I). F-actin was labeled with phalloidin conjugated to the new long-wavelength fluorophore BODIPY 581/591 (581-nm excitation, 591-nm emission), which is spectrally similar to Texas Red. The G-actin appeared as pervasive green fluorescence that was more intense in the nuclear region, where cell thickness is greater and stress fibers are less frequent. in addition, we observed a punctate fluorescein pattern around the nuclei and in other parts of the cells, suggesting that some G-actin is localized to small discrete sites. F-actin was observed as red fluorescent filaments. Unlabeled DNAse I effectively prevented staining of G-actin by the fluorescent DNAse I conjugates. The specificity of DNAse I for G-actin was confirmed by the presence of a single labeled band with molecular weight corresponding to actin in a Western blot of total cytoplasmic endothelial proteins reacted with biotin-DNAse I-streptavidin-alkaline phosphatase. Anti-actin antibody, which associates with both G- and F-actin, in conjunction with fluorescent secondary antibody produced a pattern similar to that obtained by simultaneous visualization with fluorescein-DNAse I and BODIPY 581/591- or rhodamine-phalloidin. C1 USA,ENVIRONM MED RES INST,NATICK,MA 01760. RP HAUGLAND, RP (reprint author), MOLEC PROBES INC,POB 22010,EUGENE,OR 97402, USA. FU NIGMS NIH HHS [R44 GM 37347] NR 34 TC 41 Z9 42 U1 0 U2 3 PU HISTOCHEMICAL SOC INC PI NEW YORK PA MT SINAI MEDICAL CENTER 19 EAST 98TH ST SUTIE 9G, NEW YORK, NY 10029 SN 0022-1554 J9 J HISTOCHEM CYTOCHEM JI J. Histochem. Cytochem. PD MAR PY 1994 VL 42 IS 3 BP 345 EP 350 PG 6 WC Cell Biology SC Cell Biology GA MX260 UT WOS:A1994MX26000007 PM 8308251 ER PT J AU HITE, JE MIH, WC AF HITE, JE MIH, WC TI VELOCITY OF AIR-CORE VORTICES AT HYDRAULIC INTAKES SO JOURNAL OF HYDRAULIC ENGINEERING-ASCE LA English DT Article ID VORTEX AB Concise equations for the tangential, radial, and axial velocities as well as the water-surface profile of air-core vortices at hydraulic intakes have been derived. The equations were developed by modifying the equation for tangential velocity originally proposed by Rosenhead in 1930. Laboratory experiments were conducted on strong air-core vortices near a water intake. The results indicate the equations agree with experimental measurements and are applicable to vortex motion in general. The equations for radial and axial vortex velocities contain an eddy-viscosity term, which should be proportional to vortex circulation. Dimensionless parameters describing the circulation and intake Froude numbers and the intake submergence are also used in the analysis. Using these equations, the depth and three velocity components of an air-core vortex at certain hydraulic intakes can be predicted. This information may be helpful to the practicing engineer in determining the submergence required to avoid air-entraining vortices at intakes. C1 WASHINGTON STATE UNIV,DEPT CIVIL & ENVIRONM ENGN,ALBROOK HYDR LAB,PULLMAN,WA 99164. RP HITE, JE (reprint author), USA,CORPS ENGINEERS,WATERWAYS EXPT STN,HYDR LAB,VICKSBURG,MS 39180, USA. NR 25 TC 43 Z9 49 U1 1 U2 4 PU ASCE-AMER SOC CIVIL ENGINEERS PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2398 SN 0733-9429 J9 J HYDRAUL ENG-ASCE JI J. Hydraul. Eng.-ASCE PD MAR PY 1994 VL 120 IS 3 BP 284 EP 297 DI 10.1061/(ASCE)0733-9429(1994)120:3(284) PG 14 WC Engineering, Civil; Engineering, Mechanical; Water Resources SC Engineering; Water Resources GA MZ042 UT WOS:A1994MZ04200001 ER PT J AU ROTHWELL, SW WRIGHT, DG AF ROTHWELL, SW WRIGHT, DG TI CHARACTERIZATION OF INFLUENZA-A VIRUS BINDING-SITES ON HUMAN NEUTROPHILS SO JOURNAL OF IMMUNOLOGY LA English DT Article ID POLYMORPHONUCLEAR LEUKOCYTE DYSFUNCTION; WISKOTT-ALDRICH SYNDROME; A VIRUS; SIALOPHORIN CD43; SIALIC-ACID; RECEPTOR DETERMINANTS; CELL ACTIVATION; INFECTION; INVITRO; SURFACE AB Exposure of human neutrophils (PMN) to influenza A virus (IAV) triggers discrete responses in these cells that interfere with their normal host defense functions. Because the restricted host range and tissue specificities of many viruses are determined by cell surface molecules acting as virus receptors on target cells, it seemed plausible that IAV might interact with neutrophils via specific plasma membrane glycoproteins that bind to viral hemagglutinin. When the binding of intact IAV (ATCC strain A/PR/8/34 (H1N1)) to PMNs was examined by flow cytometry, virus binding was found to be saturable and to be diminished after extensive desialation of the cells with neuraminidase. Stimulation of PMNs with FMLP (0.1 mu M) caused a transient increase in IAV binding that was maximal (>200%) at 2 min after stimulation. When neutrophil membrane proteins were separated by gel electrophoresis and transferred to nitrocellulose, IAV bound selectively to two polypeptide bands of approximately 125 and 160 kDa. Relative binding to these two bands was modified and ultimately eliminated by treatment of PMN membrane proteins with neuraminidase before electrophoresis and blotting. Intact virus precipitated a limited number of proteins from solubilized PMN plasma membrane preparations, and Abs specific for sialophorin (CD43) recognized virus-precipitated PMN membrane proteins of the same apparent m.w. as those detected in virus-membrane protein blots. These findings indicate that IAV binds to human PMNs through interactions with a limited number of PMN membrane glycoproteins, which include sialophorin (CD43). RP ROTHWELL, SW (reprint author), WALTER REED ARMY INST RES,DEPT HEMATOL,WASHINGTON,DC 20307, USA. NR 56 TC 19 Z9 19 U1 0 U2 0 PU AMER ASSOC IMMUNOLOGISTS PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 0022-1767 J9 J IMMUNOL JI J. Immunol. PD MAR 1 PY 1994 VL 152 IS 5 BP 2358 EP 2367 PG 10 WC Immunology SC Immunology GA NB988 UT WOS:A1994NB98800033 PM 8133046 ER PT J AU BACA, LM GENIS, P KALVAKOLANU, D SEN, G MELTZER, MS ZHOU, A SILVERMAN, R GENDELMAN, HE AF BACA, LM GENIS, P KALVAKOLANU, D SEN, G MELTZER, MS ZHOU, A SILVERMAN, R GENDELMAN, HE TI REGULATION OF INTERFERON-ALPHA-INDUCIBLE CELLULAR GENES IN HUMAN IMMUNODEFICIENCY VIRUS-INFECTED MONOCYTES SO JOURNAL OF LEUKOCYTE BIOLOGY LA English DT Article DE HIV-INJECTED MONOCYTES; IFN-ALPHA-INDUCIBLE GENES; VESICULAR STOMATITIS VIRUS ID VESICULAR STOMATITIS-VIRUS; BLOOD MONONUCLEAR-CELLS; DOUBLE-STRANDED-RNA; INFLUENZA-VIRUS; HIV-INFECTION; GAMMA-INTERFERONS; RESPONSE ELEMENT; KAPOSIS SARCOMA; PROTEIN-KINASE; IFN-ALPHA AB Cellular mechanisms that control susceptibility to opportunistic infection in human immunodeficiency virus (HIV)-infected individuals remain poorly understood. HIV may induce certain cellular genes that restrict HIV replication and protect cells against other superinfecting viral pathogens. Indeed, HIV-infected monocytes resist infection by vesicular stomatitis virus (VSV). HIV-induced VSV interference in monocytes increases with time after HIV infection. Such interference was evident 6 h after HIV infection and reached maximal levels at 14 days. Monocytotropic but not T cell-tropic HIV strains elicited these effects, signaling a requirement for viral entry and/or replication. Viral interference was independent of interferon (IFN) and was unaffected by addition of neutralizing IFN-alpha and -beta antibodies. The well-described IFN-alpha-inducible antiviral pathways were examined to determine their relationship to the cellular mechanism(s) underlying VSV interference. HIV and IFN-alpha both induced the expression of 2-5A synthetase and Mx gene. In contrast, the guanylate-binding protein (GBP), 6-16, and 9-27 cellular genes were up-regulated by IFN-alpha but not HIV. MxA was detected in HIV-infected monocytes but not in uninfected monocytes. The association between Mx expression and resistance to VSV, coupled with previously described anti-VSV activities by human MxA, suggested that Mr may be an effector molecule for the HIV-induced anti-VSV activities. These results, taken together, suggest that HIV can induce antiviral cellular gene expression, independent of IFN. C1 UNIV NEBRASKA,MED CTR,DEPT PATHOL & MICROBIOL,VIRAL PATHOGENESIS LAB,OMAHA,NE 68194. UNIV NEBRASKA,MED CTR,DEPT MED,VIRAL PATHOGENESIS LAB,OMAHA,NE. CLEVELAND CLIN FDN,CLEVELAND,OH. WALTER REED ARMY INST RES,DEPT CELLULAR IMMUNOL,WASHINGTON,DC. FU FDA HHS [2R01BL43628-04A1]; NIAID NIH HHS [R01 AI28253]; NINDS NIH HHS [P01 NS31492-01] NR 59 TC 43 Z9 43 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0741-5400 J9 J LEUKOCYTE BIOL JI J. Leukoc. Biol. PD MAR PY 1994 VL 55 IS 3 BP 299 EP 309 PG 11 WC Cell Biology; Hematology; Immunology SC Cell Biology; Hematology; Immunology GA MZ645 UT WOS:A1994MZ64500002 PM 7509841 ER PT J AU VEZZOLI, GC CHEN, MF BURKE, T AF VEZZOLI, GC CHEN, MF BURKE, T TI THE PREONSET, TRANSITIONAL, AND FOOT REGIONS IN RESISTANCE VS TEMPERATURE BEHAVIOR IN HIGH-CRITICAL TEMPERATURE SUPERCONDUCTING CUPRATES - INFERENCES REGARDING MAXIMUM CRITICAL-TEMPERATURE SO JOURNAL OF LOW TEMPERATURE PHYSICS LA English DT Article ID TC Y1BA2CU3O7-DELTA SUPERCONDUCTOR; HIGH MAGNETIC-FIELDS; THERMOMETRY; RESISTORS; CONTACTS; SYSTEM AB We have studied the pre-onset deviation-from-linearity region, the transitional regime, and the foot region in the resistance vs temperature behavior of high-Critical Temperature oxide superconductors, employing time-varying magnetic fields and carefully controlled precise temperatures. We have previously shown that the best value of critical temperature can be extrapolated from the magnetic field induced divergence of the resistance vs inverse absolute temperature data as derived from the transitional and/or foot regions, and that these data are in accord with results from Hall effect studies. The pre-onset region however, shows a differing non-diverging behavior. However sweep magnetic field studies show that, as a function of field, differential resistance data points corresponding to temperature values in the normal state, pre-onset state, and transitional state all lie on a straight line, whereas data points corresponding to the foot region and zero resistance region deviate from this line. We interpret these data to indicate that the phenomena that govern the pre-onset state constitute a different stage of processes that arise initially in the normal state at temperature slightly greater than the critical temperature, and continue in the transitional state at temperature slightly less than the critical temperature. We believe that the lifetime of the particle that mediates Cooper-pairing establishes these different stages of the process leading to superconductivity in the cuprates. C1 USA, PULSED POWER BRANCH, FT MONMOUTH, NJ 07703 USA. RP VEZZOLI, GC (reprint author), USA, RES LAB, CERAM RES BRANCH, WATERTOWN, MA 02172 USA. NR 30 TC 3 Z9 3 U1 0 U2 1 PU SPRINGER/PLENUM PUBLISHERS PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 0022-2291 EI 1573-7357 J9 J LOW TEMP PHYS JI J. Low Temp. Phys. PD MAR PY 1994 VL 94 IS 5-6 BP 637 EP 645 DI 10.1007/BF00753832 PG 9 WC Physics, Applied; Physics, Condensed Matter SC Physics GA NC774 UT WOS:A1994NC77400011 ER PT J AU TURELL, MJ BEAMAN, JR NEELY, GW AF TURELL, MJ BEAMAN, JR NEELY, GW TI EXPERIMENTAL TRANSMISSION OF EASTERN EQUINE ENCEPHALITIS-VIRUS BY STRAINS OF AEDES-ALBOPICTUS AND A-TAENIORHYNCHUS (DIPTERA, CULICIDAE) SO JOURNAL OF MEDICAL ENTOMOLOGY LA English DT Article DE AEDES-ALBOPICTUS; VECTOR COMPETENCE; EASTERN EQUINE ENCEPHALITIS VIRUS ID ENCEPHALOMYELITIS VIRUS; CHIKUNGUNYA VIRUS; SUSCEPTIBILITY; INFECTION; AMERICA; AEGYPTI; FLORIDA; NORTH AB The vector competence of Aedes taeniorhynchus (Wiedemann) and four strains of Aedes albopictus (Skuse) was assessed for eastern equine encephalitis (EEE) virus isolated from Ae. albopictus collected in Polk County, Florida. Both species became infected with and transmitted EEE virus by bite after feeding on 1-d-old chicks that had been inoculated with EEE virus (viremia = 10(10.1) plaque-forming units [PFU] per ml of blood). However, when fed on an older chick with a lower viremia (viremia = 10(6.1) PFU per ml of blood), Ae. albopictus was significantly more susceptible to infection (90%, n = 61) than was Ae. taeniorhynchus (15%, n = 40). Transmission was also significantly more efficient by Ae. albopictus (36%, n = 44), than by Ae. taeniorhynchus (0%, n = 14). These data, combined with the recent isolation of EEE virus from Ae. albopictus and its opportunistic feeding behavior, indicate that Ae. albopictus could function as a bridge vector between the enzootic Culiseta melanura (Coq.)-avian cycle and susceptible mammalian hosts. RP TURELL, MJ (reprint author), USA,MED RES INST INFECT DIS,DIV APPL RES,FREDERICK,MD 21702, USA. NR 20 TC 22 Z9 22 U1 0 U2 1 PU ENTOMOL SOC AMER PI LANHAM PA 9301 ANNAPOLIS RD, LANHAM, MD 20706 SN 0022-2585 J9 J MED ENTOMOL JI J. Med. Entomol. PD MAR PY 1994 VL 31 IS 2 BP 287 EP 290 PG 4 WC Entomology; Veterinary Sciences SC Entomology; Veterinary Sciences GA MZ394 UT WOS:A1994MZ39400015 PM 8189419 ER PT J AU LINTHICUM, KJ LOGAN, TM AF LINTHICUM, KJ LOGAN, TM TI WEIGHT-GAIN, HEMOGLOBIN UPTAKE, AND VIRUS INGESTION BY HYALOMMA-TRUNCATUM (ACARI, IXODIDAE) TICKS AFTER ENGORGEMENT ON VIREMIC GUINEA-PIGS SO JOURNAL OF MEDICAL ENTOMOLOGY LA English DT Note DE IXODIDAE; HYALOMMA-TRUNCATUM; ARBOVIRUS ID HEMORRHAGIC-FEVER VIRUS; TRANSMISSION; INFECTION AB The ability of guinea pigs to serve as a source of an arbovirus for feeding ticks was examined with Hyalomma truncatum Koch and Venezuelan equine encephalomyelitis virus. Ticks fed on guinea pigs to varying degrees, as indicated by both low and high weight gain and hemoglobin uptake. Pools of larval ticks measured at drop-off with undetectable or very low hemoglobin levels (mean hemoglobin content = 0.05 mg per pool) contained the same amount of virus (>10(3.0) plaque-forming units [PFU] per pool) as pools of ticks with high hemoglobin levels (mean hemoglobin = 0.15 mg per pool). A group of nymphs that ingested a mean of 0.13 mg of hemoglobin contained the same amount of virus (mean viral titer almost-equal-to 10(2.5) PFU) as a group of nymphs that ingested 0.32 mg of hemoglobin. Some adult ticks that ingested <0.35 mg of hemoglobin contained more virus than adults that ingested >4.7 mg of hemoglobin. C1 USA,MED RES INST INFECT DIS,DEPT EPIDEMIOL,DIV APPL RES,FREDERICK,MD 21702. NR 13 TC 1 Z9 1 U1 0 U2 0 PU ENTOMOL SOC AMER PI LANHAM PA 9301 ANNAPOLIS RD, LANHAM, MD 20706 SN 0022-2585 J9 J MED ENTOMOL JI J. Med. Entomol. PD MAR PY 1994 VL 31 IS 2 BP 306 EP 309 PG 4 WC Entomology; Veterinary Sciences SC Entomology; Veterinary Sciences GA MZ394 UT WOS:A1994MZ39400019 PM 8189423 ER PT J AU BRAZAITIS, MP MIRVIS, SE GREENBERG, J ORD, RA AF BRAZAITIS, MP MIRVIS, SE GREENBERG, J ORD, RA TI SEVERE RETROPERITONEAL HEMORRHAGE COMPLICATING ANTERIOR ILIAC BONE-GRAFT ACQUISITION SO JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY LA English DT Note ID DONOR SITES C1 UNIV MARYLAND,HOSP MED SYST,DEPT DIAGNOST RADIOL,22 S GREENE ST,BALTIMORE,MD 21201. WALTER REED ARMY MED CTR,DEPT DIAGNOST RADIOL,WASHINGTON,DC 20307. UNIV MARYLAND MED SYST,DEPT DIAGNOST RADIOL,BALTIMORE,MD. NR 13 TC 7 Z9 7 U1 0 U2 0 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0278-2391 J9 J ORAL MAXIL SURG JI J. Oral Maxillofac. Surg. PD MAR PY 1994 VL 52 IS 3 BP 314 EP 316 DI 10.1016/0278-2391(94)90309-3 PG 3 WC Dentistry, Oral Surgery & Medicine SC Dentistry, Oral Surgery & Medicine GA MY544 UT WOS:A1994MY54400028 PM 8308634 ER PT J AU STUREK, WB NIETUBICZ, CJ SAHU, J WEINACHT, P AF STUREK, WB NIETUBICZ, CJ SAHU, J WEINACHT, P TI APPLICATIONS OF COMPUTATIONAL FLUID-DYNAMICS TO THE AERODYNAMICS OF ARMY PROJECTILES SO JOURNAL OF SPACECRAFT AND ROCKETS LA English DT Article AB The ability to predict the complete set of aerodynamic performance parameters for projectile configurations is the goal of the computational aerodynamicists at the U.S. Army Research Laboratory. To achieve this goal, predictive capabilities that use Navier-Stokes computational techniques have been developed and applied to an extensive number of projectile configurations. A summary of code validation efforts and applications for both spin-stabilized and fin-stabilized projectile configurations are described. Significant progress in the predictive capability for projectile aerodynamics has been achieved through the availability of substantial supercomputer resources and modern computational techniques. Current and future research areas of interest are described and provide an indication of computer resources and code enhancements needed to continue the progress in projectile computational aerodynamics. C1 USA,RES LAB,AERODYNAM BRANCH,DIV PROP & FLIGHT,WEAPONS TECHNOL DIRECTORATE,ABERDEEN PROVING GROUND,MD 21005. RP STUREK, WB (reprint author), USA,RES LAB,DIV COMPUTAT SCI & TECHNOL,ADV COMPUTAT & INFORMAT SCI DIRECTORATE,ABERDEEN PROVING GROUND,MD 21005, USA. NR 44 TC 11 Z9 11 U1 0 U2 0 PU AMER INST AERONAUT ASTRONAUT PI RESTON PA 1801 ALEXANDER BELL DRIVE, STE 500, RESTON, VA 22091 SN 0022-4650 J9 J SPACECRAFT ROCKETS JI J. Spacecr. Rockets PD MAR-APR PY 1994 VL 31 IS 2 BP 186 EP 199 DI 10.2514/3.26422 PG 14 WC Engineering, Aerospace SC Engineering GA NG692 UT WOS:A1994NG69200008 ER PT J AU OGURA, H CIOFFI, WG OKERBERG, CV JOHNSON, AA GUZMAN, RF MASON, AD PRUITT, BA AF OGURA, H CIOFFI, WG OKERBERG, CV JOHNSON, AA GUZMAN, RF MASON, AD PRUITT, BA TI THE EFFECTS OF PENTOXIFYLLINE ON PULMONARY-FUNCTION FOLLOWING SMOKE-INHALATION SO JOURNAL OF SURGICAL RESEARCH LA English DT Article ID TUMOR-NECROSIS-FACTOR; INDUCED LUNG INJURY; PLATELET-ACTIVATING-FACTOR; NEUTROPHIL FUNCTION; OVINE MODEL; INHIBITION; GRANULOCYTE; ATTENUATION; LEUKOCYTES; SHOCK AB Bronchopulmonary injury secondary to smoke inhalation is a significant comorbid factor following major thermal trauma. The present study evaluates the effects of pentoxifylline (PTX) on pulmonary function in an ovine model of inhalation injury. Following smoke exposure to produce a moderate inhalation injury, 16 animals were divided into two groups. Group 1 animals (n = 8) were untreated; Group 2 animals (n = 8) were treated continuously with pentoxifylline following smoke exposure. The animals were observed in the unintubated, awake state for 48 hr. Cardiopulmonary variables and blood gases were measured serially. Ventilation perfusion distribution (V-A/Q), analyzed using the multiple inert gas elimination technique, and bronchoalveolar lavage (BAL) were performed at 48 hr. The wet to dry lung weight ratio was measured following necropsy. In Group 2, the progressive hypoxemia observed following smoke inhalation was attenuated with less V-A/Q mismatching than in Group 1 (P < 0.05). Pulmonary hypertension secondary to increased vascular resistance was also attenuated in Group 2 (P < 0.05). In BAL fluid, polymorphonuclear leukocytes, total protein content, and conjugated dienes were less in Group 2 than in Group 1 (P < 0.05). Plasma-conjugated diene levels were also lower in Group 2 at 48 hr. Extravascular lung water and decrease in lung compliance were greater in Group 1. There was less morphologic evidence of airway injury in Group 2 compared to Group 1. The improvement of pulmonary function following treatment with PTX suggests that this agent may be useful in the management of smoke inhalation injury. RP OGURA, H (reprint author), USA,INST SURG RES,FT SAM HOUSTON,TX 78234, USA. NR 47 TC 25 Z9 26 U1 0 U2 1 PU ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 SN 0022-4804 J9 J SURG RES JI J. Surg. Res. PD MAR PY 1994 VL 56 IS 3 BP 242 EP 250 DI 10.1006/jsre.1994.1038 PG 9 WC Surgery SC Surgery GA MZ010 UT WOS:A1994MZ01000006 PM 8145541 ER PT J AU BARRETT, AH CARDELLO, AV LESHER, LL TAUB, IA AF BARRETT, AH CARDELLO, AV LESHER, LL TAUB, IA TI CELLULARITY, MECHANICAL FAILURE, AND TEXTURAL PERCEPTION OF CORN MEAL EXTRUDATES SO JOURNAL OF TEXTURE STUDIES LA English DT Article ID EXTRUSION-COOKING; STARCH; CRISPNESS; MOISTURE AB Relationships among cellular structure, fracturability, and sensory properties in porous, brittle extrudates were investigated. Corn-based extrudates intentionally processed to exhibit a range of physical structures were characterized in terms of cell size distribution, bulk density, mechanical strength, fracturability, and sensory attributes. These measurements show both mechanical strength, defined by average compressive stress during extended deformation, and fracturability, quantified by fractal and Fourier analyses of stress-strain functions, increasing with either decreasing mean cell size or increasing bulk density. Fracturability parameters or structural characteristics are furthermore correlated with sensory scores for crunchiness, crispness, hardness and perceived density. These results indicate that cellularity strongly influences the pattern of mechanical failure and that failure characteristics, such as fractal dimension or power spectrum of stress strain functions, are reflective of sensory texture. C1 USA,NATICK RES DEV & ENGN CTR,SOLDIER SCI DIRECTORATE,NATICK,MA 01760. RP BARRETT, AH (reprint author), USA,NATICK RES DEV & ENGN CTR,FOOD ENGN DIRECTORATE,NATICK,MA 01760, USA. NR 41 TC 69 Z9 71 U1 0 U2 3 PU FOOD NUTRITION PRESS INC PI TRUMBULL PA 6527 MAIN ST, P O BOX 374, TRUMBULL, CT 06611 SN 0022-4901 J9 J TEXTURE STUD JI J. Texture Stud. PD MAR PY 1994 VL 25 IS 1 BP 77 EP 95 DI 10.1111/j.1745-4603.1994.tb00756.x PG 19 WC Food Science & Technology SC Food Science & Technology GA ND283 UT WOS:A1994ND28300006 ER PT J AU MOORE, JW GEORGE, L KIRKPATRICK, SE MATHEWSON, JW SPICER, RL UZARK, K ROTHMAN, A CAMBIER, PA SLACK, MC KIRBY, WC AF MOORE, JW GEORGE, L KIRKPATRICK, SE MATHEWSON, JW SPICER, RL UZARK, K ROTHMAN, A CAMBIER, PA SLACK, MC KIRBY, WC TI PERCUTANEOUS CLOSURE OF THE SMALL PATENT DUCTUS-ARTERIOSUS USING OCCLUDING SPRING COILS SO JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY LA English DT Article ID TRANSCATHETER CLOSURE; CLINICAL-APPLICATION; CATHETER OCCLUSION; RESIDUAL SHUNTS; FOLLOW-UP AB Objectives. This report summarizes our experience with the use of occluding spring coils to close the small patent ductus arteriosus. Background. Several patent ductus arteriosus occluders (most notably the Rashkind device) have been developed and studied. Occluding spring coils have been used to close abnormal vessels and. vascular connections. We previously reported the use of occluding spring coils to close the small patent ductus arteriosus in a small group of patients. This report describes our series of patients having patent ductus arteriosus closure with occluding spring coils. Methods. Between June 1990 and June 1993, 30 patients underwent cardiac catheterization to have patent ductus arteriosus closure by occluding spring coils. Selection criteria were age >6 months and narrowest patent ductus arteriosus internal dimension less than or equal to 3.0 mm by color how imaging. Definitive selection war; based on review of aortograms performed at catheterization. A 5.2F coronary catheter was used to deliver one or two standard occluding spring coils. A loop was delivered in the main pulmonary artery, and the remainder of the coil was delivered across the patent ductus arteriosus and into the aortic diverticulum. Patent ductus arteriosus closure was confirmed by aortography or color how imaging, or both. Follow up after coil placement occurred at 6 weeks and 6 months and included two-view chest radiography, echocardiography and color flow imaging. Results. Of the 30 patients, 29 had successful implantation by one (27 patients) or two (2 patients) occluding spring coils. Of these 29 patients, 19 had a clinically apparent and 10 had a silent patent ductus arteriosus. Average ductus minimal internal dimension was 1.7 mm (range 1.0 to 3.0). Complete closure of the ductus was confirmed in 27 patients by aortography or color flow imaging or both (in 24 within 4 h, in 2 after 6 weeks and in 1 after 6 months). Six weeks after implantation, two patients had a tiny residual patent ductus arteriosus noted on color flow imaging. One patient did not have successful implantation. This patient had a 3.2-mm ductus, and two coils migrated to the distal left pulmonary artery and could not be retrieved. There were no deaths or any significant complications noted during early or late follow-up in these patients. Conclusions. Occluding spring coils may have additional application in closing the small patent ductus arteriosus. C1 UNIV CALIF SAN DIEGO,SCH MED,DIV PEDIAT CARDIOL,SAN DIEGO,CA 92123. WALTER REED ARMY MED CTR,DIV PEDIAT CARDIOL,WASHINGTON,DC 20307. RP MOORE, JW (reprint author), CHILDRENS HOSP,DIV CARDIOL,3020 CHILDRENS WAY,MC 5004,SAN DIEGO,CA 92123, USA. NR 24 TC 176 Z9 186 U1 0 U2 2 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0735-1097 J9 J AM COLL CARDIOL JI J. Am. Coll. Cardiol. PD MAR 1 PY 1994 VL 23 IS 3 BP 759 EP 765 PG 7 WC Cardiac & Cardiovascular Systems SC Cardiovascular System & Cardiology GA PH369 UT WOS:A1994PH36900031 PM 8113562 ER PT J AU CESPEDES, RD CABALLERO, RL PERETSMAN, SJ THOMPSON, IM AF CESPEDES, RD CABALLERO, RL PERETSMAN, SJ THOMPSON, IM TI CRYPTIC PRESENTATIONS OF GERM-CELL TUMORS SO JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS LA English DT Article AB The records of 636 patients who were treated for carcinoma of the testis were reviewed. Of these patients, 61 (9.6 percent) presented with extratesticular complaints. In order of decreasing frequency, the complaints were pain (abdominal, back or groin), gynecomastia or mastodynia, pulmonary complaints, enlarged lymph nodes or a nontesticular mass, swelling of the lower extremity or neurologic changes. A substantial number of these patients were initially misdiagnosed and underwent a surgical procedure. Of importance, most of these patients had either abnormal testicular examination results, elevated markers or a history of cryptorchidism. The data suggest that patients with germ cell tumors, even when presenting with cryptic complaints, can readily be diagnosed if a high level of suspicion is maintained, a careful testicular examination is performed and tumor markers obtained. This frequently makes a diagnostic abdominal exploration or other surgical interventions unnecessary. C1 BROOKE ARMY MED CTR,DEPT UROL,SAN ANTONIO,TX. RP CESPEDES, RD (reprint author), WILFORD HALL USAF MED CTR,DEPT UROL,SAN ANTONIO,TX, USA. NR 4 TC 3 Z9 3 U1 0 U2 0 PU AMER COLL SURGEONS PI CHICAGO PA 54 EAST ERIE ST, CHICAGO, IL 60611 SN 1072-7515 J9 J AM COLL SURGEONS JI J. Am. Coll. Surg. PD MAR PY 1994 VL 178 IS 3 BP 261 EP 265 PG 5 WC Surgery SC Surgery GA MZ644 UT WOS:A1994MZ64400010 PM 8149018 ER PT J AU PETRAS, JM AF PETRAS, JM TI NEUROLOGY AND NEUROPATHOLOGY OF SOMAN-INDUCED BRAIN INJURY - AN OVERVIEW SO JOURNAL OF THE EXPERIMENTAL ANALYSIS OF BEHAVIOR LA English DT Article DE SOMAN; NEUROPATHOLOGY; REVIEW; ORGANOPHOSPHATE ID DIISOPROPYL PHOSPHOROFLUORIDATE DFP; RATS; PATTERNS AB Battlefield use of nerve agents poses serious medical threats to combat troops and to civilians in the immediate or adjacent environment. The experiments reported herein were carried out in the 1980s to help to define both the neurological and neuropathological consequences of exposure to the organophosphate nerve agent Soman. These data contributed to the scientific foundation for a program of drug development to find agents that would prevent or reduce the risk of injury to the central nervous system and specifically pointed to the importance of including an anticonvulsant in the treatment of agent exposure. Since these experiments were conducted, research efforts have continued to improve pretreatment and treatment, such as the inclusion of the anticonvulsant diazepam in the medical treatment of exposed personnel. RP PETRAS, JM (reprint author), USA,WALTER REED ARMY INST RES,DEPT MED NEUROSCI,DIV NEUROPSYCHIAT,WASHINGTON,DC 20307, USA. NR 39 TC 57 Z9 59 U1 0 U2 1 PU SOC EXP ANALYSIS BEHAVIOR INC PI BLOOMINGTON PA INDIANA UNIV DEPT PSYCHOLOGY, BLOOMINGTON, IN 47405 SN 0022-5002 J9 J EXP ANAL BEHAV JI J. Exp. Anal. Behav. PD MAR PY 1994 VL 61 IS 2 BP 319 EP 329 DI 10.1901/jeab.1994.61-319 PG 11 WC Psychology, Biological; Behavioral Sciences; Psychology, Experimental SC Psychology; Behavioral Sciences GA NB467 UT WOS:A1994NB46700018 PM 8169578 ER PT J AU WILLIAMSON, RL TANNER, SN AF WILLIAMSON, RL TANNER, SN TI WHERE HAVE ALL THE SAGES GONE SO JOURNAL OF THE IES LA English DT Article DE ENVIRONMENT; PARADIGMS; SIMULATION; DATABASE; SYNTHETIC BATTLEFIELD; TAILORING AB This paper explores various mindsets or paradigms that govern how we consider environmental factors in materiel system design and testing. It particularly cautions against hidden paradigms that may restrict initiatives to increase the efficiency of the materiel acquisition cycle. It also explains paradigm shifts from producing and testing prototypes to substituting simulation for hardware where possible to save time and reduce costs. The key factor in shifting successfully from hardware to simulation is the sage advice and guidance of environmental experts whose basic knowledge of environmental effects is essential in efforts to structure information and experience into databases, models, and simulations. It is shown how the Institute of Environmental Sciences (IES) plays a key role in bringing experts together to address the Department of Defense (DoD) synthetic environment science and technology thrust. RP WILLIAMSON, RL (reprint author), USA,TEST & EVALUAT COMMAND,ABERDEEN PROVING GROUND,MD, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU INST ENVIRONMENTAL SCI PI MT PROSPECT PA 940 E NORTHWEST HIGHWAY, MT PROSPECT, IL 60056 SN 1052-2883 J9 J IES JI J. IES PD MAR-APR PY 1994 VL 37 IS 2 BP 29 EP 33 PG 5 WC Engineering, Environmental; Environmental Sciences; Instruments & Instrumentation SC Engineering; Environmental Sciences & Ecology; Instruments & Instrumentation GA NF570 UT WOS:A1994NF57000003 ER PT J AU ARROYO, CM KIRBY, SD WERRLEIN, RJ MCCARTHY, RL MORAN, TS KEELER, JR AF ARROYO, CM KIRBY, SD WERRLEIN, RJ MCCARTHY, RL MORAN, TS KEELER, JR TI REACTIVE OXYGEN SPECIES PRODUCED IN METAL-CATALYZED OXIDATION OF BIS(TRIFLUOROMETHYL)DISULFIDE AND PROTECTION BY ZE(TM) SO JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH LA English DT Article ID ELECTRON-SPIN RESONANCE; FREE-RADICALS; ZINC; 5,5-DIMETHYL-1-PYRROLINE-1-OXIDE; ANTIOXIDANT; CHEMISTRY; AGENTS; CELLS; TRAP AB Bis(trifluoromethyl)disulfide (TFD), used as an industrial fumigant, was found to generate a thiyl free radical as seen by EPR/spin trapping. Oxygen appears to be an absolute requirement for radical production. The results obtained in this investigation implicate the production of thiyl and reactive oxygen species (ROS), superoxide radical anion and hydroxyl radicals, during TFD autoxidation. The rate of production of these free radical intermediates was found to increase in the presence of iron(III) and copper(II). In addition, the metal ion chelator DETAPAC and ROS scavengers ethanol, mannitol, and PEG-SOD/catalase were found to inhibit free radical production. Reactive oxygen species were not formed when a high-potency zinc plus antioxidant, ZE caps(TM), was present. These results provide support for the pro-oxidation of TFD and a protective role for zinc. RP ARROYO, CM (reprint author), USA,MED RES INST CHEM DEF,ABERDEEN PROVING GROUND,MD 21010, USA. NR 37 TC 0 Z9 0 U1 0 U2 2 PU TAYLOR & FRANCIS PI BRISTOL PA 1900 FROST ROAD, SUITE 101, BRISTOL, PA 19007-1598 SN 0098-4108 J9 J TOXICOL ENV HEALTH JI J. Toxicol. Environ. Health PD MAR PY 1994 VL 41 IS 3 BP 329 EP 344 PG 16 WC Environmental Sciences; Public, Environmental & Occupational Health; Toxicology SC Environmental Sciences & Ecology; Public, Environmental & Occupational Health; Toxicology GA NB944 UT WOS:A1994NB94400006 PM 8126753 ER PT J AU YOON, YJ LU, YC LALEVIC, B ZETO, RJ AF YOON, YJ LU, YC LALEVIC, B ZETO, RJ TI SILICON VACUUM MICRODIODE WITH ON-CHIP ANODE SO JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B LA English DT Article ID AVALANCHE CATHODES AB A vacuum microdiode was fabricated with a silicon avalanche cathode and an on-chip microanode. The image reverse process followed by proper heat treatment was employed to form a photoresist sacrificial layer in shaping a microanode. The distance of approximately 3 mum between cathode and anode was achieved by adjusting the number of depositions of photoresist. On the top of the sacrificial layer, a multilayer (Al/TiW/Al) structure was deposited, which provided the microanode with good conductivity and mechanical strength. The dimension of the microanode was 8 (or 18) mum in width and more than 30 mum in length. The I-V characteristics of this vertical-type microdiode demonstrated the enhancement of current emission due to a strong electric field at relatively low anode voltages. C1 USA,RES LAB,AMSRL EP ED,ELECTR & POWER SOURCES DIRECTORATE,FT MONMOUTH,NJ 07703. RP YOON, YJ (reprint author), RUTGERS STATE UNIV,DEPT ELECT & COMP ENGN,PISCATAWAY,NJ 08855, USA. NR 10 TC 2 Z9 2 U1 0 U2 0 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 1071-1023 J9 J VAC SCI TECHNOL B JI J. Vac. Sci. Technol. B PD MAR-APR PY 1994 VL 12 IS 2 BP 648 EP 651 DI 10.1116/1.587405 PG 4 WC Engineering, Electrical & Electronic; Nanoscience & Nanotechnology; Physics, Applied SC Engineering; Science & Technology - Other Topics; Physics GA NG711 UT WOS:A1994NG71100023 ER PT J AU VECHT, A SMITH, DW CHADHA, SS GIBBONS, CS KOH, J MORTON, D AF VECHT, A SMITH, DW CHADHA, SS GIBBONS, CS KOH, J MORTON, D TI NEW ELECTRON EXCITED LIGHT-EMITTING MATERIALS SO JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B LA English DT Article ID FLUORESCENT AB A range of bright, multicolor phosphor systems for field emission displays is reported. These include the standard ZnO:Zn and newer, narrow band emitting systems based on green ZnGa2O4:Mn and red CaTiO3:Pr. A modified, blue emitting ZnO:(Zn/Mg) and thin films of ZnGa2O4:Mn have also been prepared. C1 USA,ELECT COMMAND,DISPLAY DEVICES TEAM,FT MONMOUTH,NJ 07703. RP VECHT, A (reprint author), UNIV GREENWICH,SCH BIOL & CHEM SCI,WELLINGTON ST,LONDON SE18 6PF,ENGLAND. NR 10 TC 115 Z9 117 U1 4 U2 17 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 1071-1023 J9 J VAC SCI TECHNOL B JI J. Vac. Sci. Technol. B PD MAR-APR PY 1994 VL 12 IS 2 BP 781 EP 784 DI 10.1116/1.587346 PG 4 WC Engineering, Electrical & Electronic; Nanoscience & Nanotechnology; Physics, Applied SC Engineering; Science & Technology - Other Topics; Physics GA NG711 UT WOS:A1994NG71100051 ER PT J AU FOUNTZOULAS, CG KATTAMIS, TZ DEMAREE, JD KOSIK, WE FRANZEN, W HIRVONEN, JK AF FOUNTZOULAS, CG KATTAMIS, TZ DEMAREE, JD KOSIK, WE FRANZEN, W HIRVONEN, JK TI MECHANICAL-PROPERTIES OF SI-DIAMOND-LIKE CARBON-FILMS FORMED BY ION-BEAM-ASSISTED DEPOSITION SO JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B LA English DT Article; Proceedings Paper CT 1st International Workshop on Plasma-Based Ion Implantation CY AUG 04-06, 1993 CL UNIV WISCONSIN MADISON, MADISON, WI SP APPL SCI & TECHNOL INC, GM CORP, HUGHES RES LABS, NATL ELECT CORP, USA, RES OFF, VARIAN ASSOC HO UNIV WISCONSIN MADISON ID COATINGS AB This article reports on the composition, microhardness, cohesion, adhesion, and friction coefficients of Si-diamondlike carbon coatings on M50 steel and silicon substrates prepared at room temperature by the ion beam assisted deposition process, using energetic Ar+ ions and tetraphenyl-tetramethyl-trisiloxane (Type 704 Dow-Coming silicone oil) as a precursor material. The thickness, microhardness, and friction coefficients of these films were investigated. The cohesion and adhesion failure loads of the films were also evaluated by automatic scratch testing in combination with optical and scanning electron microscopy observation of the scratch. Rutherford backscattering spectroscopy analysis showed that film stoichiometry is insensitive to deposition parameters including the relative arrival ratios of Ar+ ions and deposited silicon-hydrocarbon molecules. Knoop microhardness values (at 25-g load) were found to vary from 800 to 1600 kg/mm2, and the unlubricated friction coefficients ranged from 0.21 to 0.27, depending on deposition parameters. C1 UNIV CONNECTICUT,STORRS,CT 06269. RP FOUNTZOULAS, CG (reprint author), USA,RES LAB,MAT DIRECTORATE,WATERTOWN,MA 02172, USA. NR 9 TC 6 Z9 6 U1 0 U2 4 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 1071-1023 J9 J VAC SCI TECHNOL B JI J. Vac. Sci. Technol. B PD MAR-APR PY 1994 VL 12 IS 2 BP 977 EP 980 DI 10.1116/1.587339 PG 4 WC Engineering, Electrical & Electronic; Nanoscience & Nanotechnology; Physics, Applied SC Engineering; Science & Technology - Other Topics; Physics GA NG711 UT WOS:A1994NG71100089 ER PT J AU THOMPSON, EF OLIVER, J AF THOMPSON, EF OLIVER, J TI WAVE GROUPING IN LOCALLY GENERATED SEAS ON SHORT FETCHES SO JOURNAL OF WATERWAY PORT COASTAL AND OCEAN ENGINEERING-ASCE LA English DT Note AB Wave staff data from the U.S. Army Corps of Engineers Floating Breakwater Prototype Test Program in Puget Sound, Wash., are analyzed for wave grouping. Most previous studies have focussed on ocean conditions. where fetches, propagation distances, and wave periods are much longer than in Puget Sound. Probabilities for groups of various length closely match previous numerical simulations. Thus grouping in short-fetch, locally generated seas at this site is well predicted by linear combination of spectral components. Sequences of waves within groups show no strong, physically justifiable trends. There is no evidence that very high waves tend to occur together in the same groups. Data are included on wave groups above the significant height and several other thresholds. C1 USA,DIV ENGN,PORTLAND,OR 97208. RP THOMPSON, EF (reprint author), USA,CORPS ENGRS,WTRWAYS EXPT STN,VICKSBURG,MS 39180, USA. NR 5 TC 1 Z9 1 U1 0 U2 0 PU ASCE-AMER SOC CIVIL ENGINEERS PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2398 SN 0733-950X J9 J WATERW PORT C-ASCE JI J. Waterw. Port Coast. Ocean Eng.-ASCE PD MAR-APR PY 1994 VL 120 IS 2 BP 220 EP 225 DI 10.1061/(ASCE)0733-950X(1994)120:2(220) PG 6 WC Engineering, Civil; Engineering, Ocean; Water Resources SC Engineering; Water Resources GA MZ358 UT WOS:A1994MZ35800006 ER PT J AU PUFFER, RL AF PUFFER, RL TI THE PATTONS - A PERSONAL HISTORY OF AN AMERICAN FAMILY - PATTON,RH SO LIBRARY JOURNAL LA English DT Book Review RP PUFFER, RL (reprint author), USA,HIST PROG,LOS ANGELES,CA, USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU BOWKER MAGAZINE GROUP CAHNERS MAGAZINE DIVISION PI NEW YORK PA 249 W 17TH ST, NEW YORK, NY 10011 SN 0363-0277 J9 LIBR J JI Libr. J. PD MAR 1 PY 1994 VL 119 IS 4 BP 95 EP 95 PG 1 WC Information Science & Library Science SC Information Science & Library Science GA MY611 UT WOS:A1994MY61100099 ER PT J AU BURGESS, EB AF BURGESS, EB TI THE ELEMENTS OF HITTING - JONES,MF SO LIBRARY JOURNAL LA English DT Book Review RP BURGESS, EB (reprint author), USA,TRALINET CTR,FT MONROE,VA, USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU BOWKER MAGAZINE GROUP CAHNERS MAGAZINE DIVISION PI NEW YORK PA 249 W 17TH ST, NEW YORK, NY 10011 SN 0363-0277 J9 LIBR J JI Libr. J. PD MAR 1 PY 1994 VL 119 IS 4 BP 117 EP 117 PG 1 WC Information Science & Library Science SC Information Science & Library Science GA MY611 UT WOS:A1994MY61100185 ER PT J AU MAGNESS, LS AF MAGNESS, LS TI HIGH-STRAIN RATE DEFORMATION BEHAVIORS OF KINETIC-ENERGY PENETRATOR MATERIALS DURING BALLISTIC IMPACT SO MECHANICS OF MATERIALS LA English DT Article; Proceedings Paper CT Symposium on Shear Instabilities and Viscoplasticity Theories, as Part of the Annual Conference of the Society-of-Engineering-Science CY SEP 14-16, 1992 CL UNIV CALIF SAN DIEGO, SAN DIEGO, CA SP SOC ENGN SCI HO UNIV CALIF SAN DIEGO AB The behaviors of a variety of high-density materials are compared in ballistic penetration experiments. The deformation and failure modes of these materials, under this high pressure and high strain rate loading environment, are studied via metallographic examinations. Stable plastic flow, leading to the development of a large ''mushroomed'' head on the penetrator, was observed for certain high-density materials, including pure tungsten, tungsten heavy alloys, and a uranium-6% niobium alloy. For two other families of uranium alloys, localization quickly develop in the plastic flow and result in a rapid discard of the deformed material from the head of the penetrator. The earlier discard of the material reduces the build-up of the mushroomed head on the penetrator, allowing these materials to penetrate more efficiently. The stability of the plastic flow of the penetrator alloy, therefore, is shown to be a key determinant of the penetration capabilities of a projectile. RP MAGNESS, LS (reprint author), USA,RES LAB,AMSRL WT TC,ABERDEEN PROVING GROUND,MD 21005, USA. NR 11 TC 54 Z9 59 U1 4 U2 21 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0167-6636 J9 MECH MATER JI Mech. Mater. PD MAR PY 1994 VL 17 IS 2-3 BP 147 EP 154 DI 10.1016/0167-6636(94)90055-8 PG 8 WC Materials Science, Multidisciplinary; Mechanics SC Materials Science; Mechanics GA NE256 UT WOS:A1994NE25600007 ER PT J AU WRIGHT, TW AF WRIGHT, TW TI TOWARD A DEFEAT INVARIANT BASIS FOR SUSCEPTIBILITY TO ADIABATIC SHEAR BANDS SO MECHANICS OF MATERIALS LA English DT Article; Proceedings Paper CT Symposium on Shear Instabilities and Viscoplasticity Theories, as Part of the Annual Conference of the Society-of-Engineering-Science CY SEP 14-16, 1992 CL UNIV CALIF SAN DIEGO, SAN DIEGO, CA SP SOC ENGN SCI HO UNIV CALIF SAN DIEGO AB In a recent paper (Wright, 1992, Int. J. Plast. 8, 583), it was argued that in order to compare the susceptibility to adiabatic shearing among different materials it is necessary to control the defect that initiates the localized shear band. Furthermore, the defect must be scaled in an appropriate way that depends on the homogeneous adiabatic response of the material. The argument was based on a linearized set of equations, rather than the complete nonlinear equations. In this paper the idea of comparing materials on the basis of a known and properly scaled defect is explored further. Computations with the fully nonlinear equations show that the scaling factors, deduced from the linearized equations, do organize the different cases over a wide range of physical parameters. The actual functional form deduced from the linearized equations, however, gives only an order of magnitude estimate for stress collapse, in most cases being a lower bound for the actual collapse point. RP WRIGHT, TW (reprint author), USA, RES LAB, SLCBR TB W, ABERDEEN PROVING GROUND, MD 21005 USA. NR 13 TC 22 Z9 23 U1 0 U2 2 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0167-6636 J9 MECH MATER JI Mech. Mater. PD MAR PY 1994 VL 17 IS 2-3 BP 215 EP 222 DI 10.1016/0167-6636(94)90061-2 PG 8 WC Materials Science, Multidisciplinary; Mechanics SC Materials Science; Mechanics GA NE256 UT WOS:A1994NE25600013 ER PT J AU LILLEGARD, WA TERRIO, JD AF LILLEGARD, WA TERRIO, JD TI APPROPRIATE STRENGTH TRAINING SO MEDICAL CLINICS OF NORTH AMERICA LA English DT Article ID VENTRICULAR DIASTOLIC FUNCTION; SKELETAL-MUSCLE; BLOOD-PRESSURE; FIBER TYPE; NEUROMUSCULAR ADAPTATIONS; DOPPLER ECHOCARDIOGRAPHY; SERUM HORMONES; WEIGHT LIFTERS; EXERCISE; HYPERTROPHY C1 UNIV WASHINGTON,SCH MED,DIV FAMILY MED,SEATTLE,WA. USA,MADIGAN ARMY MED CT,DEPT FAMILY PRACTICE,FT LEWIS,WA. RP LILLEGARD, WA (reprint author), UNIFORMED SERV UNIV HLTH SCI,DEPT FAMILY PRACTICE,4301 JONES BRIDGE RD,BETHESDA,MD 20814, USA. NR 72 TC 18 Z9 19 U1 0 U2 2 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0025-7125 J9 MED CLIN N AM JI Med. Clin. N. Am. PD MAR PY 1994 VL 78 IS 2 BP 457 EP 477 PG 21 WC Medicine, General & Internal SC General & Internal Medicine GA MZ177 UT WOS:A1994MZ17700012 PM 8121222 ER PT J AU BOYLE, WE AF BOYLE, WE TI UNDER THE BLACK FLAG - EXECUTION AND RETALIATION IN MOSBYS CONFEDERACY SO MILITARY LAW REVIEW LA English DT Article RP BOYLE, WE (reprint author), USA,JUDGE ADVOCATE GEN CORPS,FT EUSTIS,VA, USA. NR 24 TC 0 Z9 0 U1 0 U2 0 PU JUDGE ADVOCATE GENERALS SCHOOL PI CHARLOTTESVILLE PA US ARMY, CHARLOTTESVILLE, VA 22903-1781 SN 0026-4040 J9 MIL LAW REV JI Milit. Law Rev. PD SPR PY 1994 VL 144 BP 148 EP 163 PG 16 WC Law SC Government & Law GA QF335 UT WOS:A1994QF33500005 ER PT J AU ELLIOTT, HW AF ELLIOTT, HW TI GOEBBELS - REUTH,RG SO MILITARY LAW REVIEW LA English DT Book Review C1 USA,JUDGE ADVOCATE GEN SCH,DIV INT LAW,WASHINGTON,DC. NR 1 TC 0 Z9 0 U1 0 U2 0 PU JUDGE ADVOCATE GENERALS SCHOOL PI CHARLOTTESVILLE PA US ARMY, CHARLOTTESVILLE, VA 22903-1781 SN 0026-4040 J9 MIL LAW REV JI Milit. Law Rev. PD SPR PY 1994 VL 144 BP 164 EP 168 PG 5 WC Law SC Government & Law GA QF335 UT WOS:A1994QF33500006 ER PT J AU SCOTT, J AF SCOTT, J TI SHE WENT TO WAR - THE CORNUM,RHONDA STORY - CORNUM,R SO MILITARY LAW REVIEW LA English DT Book Review C1 USA,JUDGE ADVOCATE GEN CORPS,WASHINGTON,DC. NR 1 TC 1 Z9 1 U1 0 U2 0 PU JUDGE ADVOCATE GENERALS SCHOOL PI CHARLOTTESVILLE PA US ARMY, CHARLOTTESVILLE, VA 22903-1781 SN 0026-4040 J9 MIL LAW REV JI Milit. Law Rev. PD SPR PY 1994 VL 144 BP 174 EP 177 PG 4 WC Law SC Government & Law GA QF335 UT WOS:A1994QF33500008 ER PT J AU BORCH, FL AF BORCH, FL TI BORN AT REVEILLE - THE MEMOIRS OF AN AMERICAN SOLDIER - REEDER,R SO MILITARY LAW REVIEW LA English DT Book Review RP BORCH, FL (reprint author), USA,JUDGE ADVOCATE GEN CORPS,DIV CRIMINAL LAW,OFF JUDGE ADVOCATE GEN,WASHINGTON,DC 20310, USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU JUDGE ADVOCATE GENERALS SCHOOL PI CHARLOTTESVILLE PA US ARMY, CHARLOTTESVILLE, VA 22903-1781 SN 0026-4040 J9 MIL LAW REV JI Milit. Law Rev. PD SPR PY 1994 VL 144 BP 178 EP 180 PG 3 WC Law SC Government & Law GA QF335 UT WOS:A1994QF33500009 ER PT J AU ELLIOTT, HW AF ELLIOTT, HW TI TERRORISM IN WAR - THE LAW OF WAR-CRIMES - LEVIE,HS SO MILITARY LAW REVIEW LA English DT Book Review C1 USA,JUDGE ADVOCATE GEN SCH,DIV INT LAW,WASHINGTON,DC. NR 1 TC 0 Z9 0 U1 0 U2 0 PU JUDGE ADVOCATE GENERALS SCHOOL PI CHARLOTTESVILLE PA US ARMY, CHARLOTTESVILLE, VA 22903-1781 SN 0026-4040 J9 MIL LAW REV JI Milit. Law Rev. PD SPR PY 1994 VL 144 BP 184 EP 187 PG 4 WC Law SC Government & Law GA QF335 UT WOS:A1994QF33500011 ER PT J AU CHISICK, M ARTHUR, JS YORK, A POINDEXTER, F AF CHISICK, M ARTHUR, JS YORK, A POINDEXTER, F TI DESIGNING A STANDARDIZED ORAL HEALTH SURVEY FOR THE TRI-SERVICES SO MILITARY MEDICINE LA English DT Article AB To address a Congressional directive for a comprehensive study of the military medical care system (including dental care), the Tri-Service Dental Chiefs convened a panel of dental epidemiologists to develop a standardized protocol for assessing the oral health of soldiers, sailors, and airmen. This paper discusses previous military and civilian oral health surveys and outlines key design features of the common military protocol that evolved from this critical review of the literature. RP CHISICK, M (reprint author), USA,INST DENT RES,EPIDEMIOL SECT,FT GEORGE G MEADE,MD 20755, USA. NR 0 TC 10 Z9 11 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD MAR PY 1994 VL 159 IS 3 BP 179 EP 186 PG 8 WC Medicine, General & Internal SC General & Internal Medicine GA NJ938 UT WOS:A1994NJ93800007 PM 8041459 ER PT J AU CLAWSON, LD JAMES, JJ AF CLAWSON, LD JAMES, JJ TI SUBSTANCE-ABUSE AND SEXUAL-ACTIVITY IN AN OVERSEAS POPULATION OF ADOLESCENT MILITARY DEPENDENTS SO MILITARY MEDICINE LA English DT Article AB To determine the incidence of high-risk behaviors, such as substance abuse and sexual activity, in an overseas population of adolescents, and how these rates compared to the general population in the United States, a survey of high school-aged military dependents residing overseas was undertaken. A questionnaire was designed and distributed to all 8th through 12th graders at the Department of Defense Dependent's School in Seoul, Korea. Use of tobacco products and a history of illicit drug use was similar to that of referant groups in the United States. Present use of illicit drugs was decreased. Use of alcohol was increased over that of similar age groups in America. The authors discuss these findings in light of the environmental differences in the overseas military community. RP CLAWSON, LD (reprint author), WALTER REED ARMY MED CTR,DEPT PSYCHIAT,WASHINGTON,DC 20307, USA. NR 0 TC 3 Z9 3 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD MAR PY 1994 VL 159 IS 3 BP 192 EP 195 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA NJ938 UT WOS:A1994NJ93800009 PM 8041461 ER PT J AU VIOLA, JM MCCARTHY, DA AF VIOLA, JM MCCARTHY, DA TI AN ECLECTIC INPATIENT TREATMENT MODEL FOR VIETNAM AND DESERT-STORM VETERANS SUFFERING FROM POSTTRAUMATIC-STRESS-DISORDER SO MILITARY MEDICINE LA English DT Article AB This paper describes the therapeutic components of an eclectic, intensive inpatient treatment strategy for Vietnam and Desert Storm veterans with posttraumatic stress disorder. A specific treatment model was devised by this author. The procedure was a collaborative effort: the staff and the patients participated in this preparatory phase treatment program at the Tripler Post-traumatic Stress Unit, Tripler Army Medical Center, Honolulu, Hawaii. The basic treatment is based on group therapy, utilizing educational, cognitive-behavioral therapy, gestalt therapy, and individualized psychotherapy, and eye movement desensitization strategies. The timing and sequencing of these treatments are a critical part of the model, and we have come to refer to it as the layered model because the treatments are layered, much like the delicious parfait dessert. RP VIOLA, JM (reprint author), TRIPLER ARMY MED CTR,3B2 PSYCHIAT,HONOLULU,HI 96859, USA. NR 0 TC 3 Z9 3 U1 1 U2 1 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD MAR PY 1994 VL 159 IS 3 BP 217 EP 220 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA NJ938 UT WOS:A1994NJ93800015 PM 8041467 ER PT J AU QUERNA, JC ROSSMANN, JA KERNS, DG AF QUERNA, JC ROSSMANN, JA KERNS, DG TI PREVALENCE OF PERIODONTAL-DISEASE IN AN ACTIVE-DUTY MILITARY POPULATION AS INDICATED BY AN EXPERIMENTAL PERIODONTAL INDEX SO MILITARY MEDICINE LA English DT Article AB An experimental periodontal screening examination and index was used to measure the prevalence of gingivitis and periodontitis among 1,334 soldiers at Fort Knox, Kentucky. Although 12.1% of the subjects demonstrated no disease, 40.3% were found to have gingivitis. In this sample group, the occurrence of gingivitis decreased with increasing age. Early periodontitis (probing depths of 3-5 mm) was detected in 35.7% of the subjects, and subjects with moderate to advanced periodontitis (probing depths greater than 5 mm) comprised 11.9% of the sample. The screening exam used is suggested for use as part of each soldier's annual dental examination. RP QUERNA, JC (reprint author), USA,DENT ACTIV,FT BENNING,GA 31905, USA. NR 0 TC 6 Z9 6 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD MAR PY 1994 VL 159 IS 3 BP 233 EP 236 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA NJ938 UT WOS:A1994NJ93800020 PM 8041472 ER PT J AU KHAN, NA PUPA, LE WELLFORD, AL PADOVE, LB MOODY, JM RUBAL, BJ AF KHAN, NA PUPA, LE WELLFORD, AL PADOVE, LB MOODY, JM RUBAL, BJ TI MANAGEMENT OF ORTHOTOPIC HEART-TRANSPLANT RECIPIENTS AT BROOKE-ARMY-MEDICAL-CENTER SO MILITARY MEDICINE LA English DT Article AB Advances in heart transplantation and post-operative rejection therapy have given new hope to patients with end-stage congestive heart failure and cardiomyopathies. The growing numbers of pre- and post-transplant patients and the complexity of their care underscore the need for a multispecialty approach to patient management. This study examines the success of a multiservice program at Brooke Army Medical Center which offers pre- and post-transplant care to active duty, dependent, and retired military personnel. RP KHAN, NA (reprint author), BROOKE ARMY MED CTR,DEPT MED,CARDIOL SERV,HSHE-MDC,FT SAM HOUSTON,TX 78234, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD MAR PY 1994 VL 159 IS 3 BP 237 EP 240 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA NJ938 UT WOS:A1994NJ93800021 PM 8041473 ER PT J AU ROTHBERG, JM KOSHES, RJ SHANAHAN, J CHRISTMAN, K AF ROTHBERG, JM KOSHES, RJ SHANAHAN, J CHRISTMAN, K TI DESERT SHIELD DEPLOYMENT AND SOCIAL-PROBLEMS ON A UNITED-STATES-ARMY COMBAT SUPPORT POST SO MILITARY MEDICINE LA English DT Article AB We undertook a study of selected mental health-related services at a combat support post to determine if stress levels surrounding Operations Desert Shield/Desert Storm had an effect on the utilization of these services. Our measure was the problem rate formed by adding the visits to the alcohol and drug service and the social work service. The findings (not all of which reached statistical significance in our small study) were that the problem rates were higher in those units which deployed, both before and after deployment. The pre-deployment differences in age, rank, and race between those soldiers deployed and not deployed is a finding which may help to account for the difference between units. There was a transient, but not sustained, problem rate increase immediately following return home for those units which deployed. Implications for mental health-related services staffing and directions for further research are discussed. RP ROTHBERG, JM (reprint author), WALTER REED ARMY INST RES,DEPT MIL PSYCHIAT,WASHINGTON,DC 20307, USA. NR 0 TC 4 Z9 4 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD MAR PY 1994 VL 159 IS 3 BP 246 EP 248 PG 3 WC Medicine, General & Internal SC General & Internal Medicine GA NJ938 UT WOS:A1994NJ93800024 PM 8041475 ER PT J AU WITTICH, AC LOCKROW, EG FOX, JT AF WITTICH, AC LOCKROW, EG FOX, JT TI LAPAROSCOPIC MANAGEMENT OF ADNEXAL TORSION IN EARLY-PREGNANCY - A CASE-REPORT SO MILITARY MEDICINE LA English DT Note RP WITTICH, AC (reprint author), TRIPLER ARMY MED CTR,DEPT OBSTET & GYNECOL,HONOLULU,HI 96859, USA. NR 0 TC 2 Z9 2 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD MAR PY 1994 VL 159 IS 3 BP 254 EP 255 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA NJ938 UT WOS:A1994NJ93800028 PM 8041478 ER PT J AU MEGO, DM AF MEGO, DM TI RAPID IMMUNOINHIBITION ASSAY FOR CK-MB - RESPONSE SO MILITARY MEDICINE LA English DT Letter RP MEGO, DM (reprint author), BROOKE ARMY MED CTR,CARDIOL SERV,FT SAM HOUSTON,TX 78234, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD MAR PY 1994 VL 159 IS 3 BP A7 EP A7 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA NJ938 UT WOS:A1994NJ93800005 ER PT J AU POLO, KB JABBARI, B AF POLO, KB JABBARI, B TI EFFECTIVENESS OF BOTULINUM TOXIN TYPE-A AGAINST PAINFUL LIMB MYOCLONUS OF SPINAL-CORD ORIGIN SO MOVEMENT DISORDERS LA English DT Note DE BOTULINUM TOXIN TYPE A; MYOCLONUS; MYOKYMIA; SPINAL CORD; SCIMITAR SYNDROME ID HEMIFACIAL SPASM; DOUBLE-BLIND; MYOKYMIA; SPASTICITY; DYSTONIAS AB Botulinum toxin is now an established treatment for blepharospasm, hemifacial spasm, spasmodic torticollis, and spastic dysphonia. We report the effectiveness of botulinum toxin against painful limb myoclonus of spinal cord origin. The patient, a 16-year-old girl with a pulmonary vascular anomaly, Scimitar syndrome, suffered from an acute spinal cord infarct at age 11. She was left with paralysis of the right leg and bladder dysfunction. Four years after the original insult, she developed ''painful cramping'' and involuntary movements of the left thigh, which were unresponsive to a wide range of therapeutic trials. The movements were continuous, rhythmic, and confined to the left quadriceps muscles. Electromyographic examination revealed continuous myoclonic discharges. Treatment with botulinum toxin in the left quadriceps muscles resulted in complete cessation of pain and marked reduction in amplitude of the movements, both clinically and electromyographically. This observation indicates the efficacy of botulinum toxin in the treatment of painful spinal myoclonus. C1 WALTER REED ARMY MED CTR,NEUROL SERV,WASHINGTON,DC 20307. UNIFORMED SERV UNIV HLTH SCI,DEPT NEUROL,BETHESDA,MD 20814. NR 24 TC 24 Z9 24 U1 1 U2 2 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0885-3185 J9 MOVEMENT DISORD JI Mov. Disord. PD MAR PY 1994 VL 9 IS 2 BP 233 EP 235 DI 10.1002/mds.870090221 PG 3 WC Clinical Neurology SC Neurosciences & Neurology GA NA179 UT WOS:A1994NA17900020 PM 8196691 ER PT J AU JABBARI, B BRAIMAN, J AF JABBARI, B BRAIMAN, J TI CONTINUOUS INVOLUNTARY AURICULAR MOVEMENTS ASSOCIATED WITH AN ANTERIOR PARIETAL TUMOR SO MOVEMENT DISORDERS LA English DT Letter C1 UNIFORMED SERV UNIV HLTH SCI,BETHESDA,MD. RP JABBARI, B (reprint author), WALTER REED ARMY MED CTR,NEUROL SERV,WASHINGTON,DC 20307, USA. NR 8 TC 1 Z9 1 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0885-3185 J9 MOVEMENT DISORD JI Mov. Disord. PD MAR PY 1994 VL 9 IS 2 BP 237 EP 238 DI 10.1002/mds.870090223 PG 2 WC Clinical Neurology SC Neurosciences & Neurology GA NA179 UT WOS:A1994NA17900022 PM 8196693 ER PT J AU URBAN, E JABBARI, B ROBLES, H AF URBAN, E JABBARI, B ROBLES, H TI CONCURRENT CEREBRAL VENOUS SINUS THROMBOSIS AND MYELORADICULOPATHY IN SJOGRENS-SYNDROME SO NEUROLOGY LA English DT Note AB A 41-year-old woman complained of severe headaches and developed quadriparesis and neurogenic bladder. Evaluation disclosed the presence of Sjogren's syndrome complicated by myeloradiculopathy with MRI evidence of cervical cord involvement. Concurrent cerebral venous sinus thrombosis was also noted. Treatment with steroids and warfarin led to clinical improvement and resolution of MRI findings. C1 WALTER REED ARMY MED CTR,DEPT RADIOL,WASHINGTON,DC 20307. RP URBAN, E (reprint author), WALTER REED ARMY MED CTR,DEPT NEUROL,NEUROL SERV,WASHINGTON,DC 20307, USA. NR 10 TC 6 Z9 6 U1 0 U2 0 PU LITTLE BROWN CO PI BOSTON PA 34 BEACON STREET, BOSTON, MA 02108-1493 SN 0028-3878 J9 NEUROLOGY JI Neurology PD MAR PY 1994 VL 44 IS 3 BP 554 EP 556 PG 3 WC Clinical Neurology SC Neurosciences & Neurology GA NB934 UT WOS:A1994NB93400035 PM 8145932 ER PT J AU CASTRO, CA GRESHAM, VC FINGER, AV MAXWELL, DM SOLANA, RP LENZ, DE BROOMFIELD, CA AF CASTRO, CA GRESHAM, VC FINGER, AV MAXWELL, DM SOLANA, RP LENZ, DE BROOMFIELD, CA TI BEHAVIORAL DECREMENTS PERSIST IN RHESUS-MONKEYS TRAINED ON A SERIAL PROBE RECOGNITION TASK DESPITE PROTECTION AGAINST SOMAN LETHALITY BY BUTYRYLCHOLINESTERASE SO NEUROTOXICOLOGY AND TERATOLOGY LA English DT Article DE SERIAL PROBE RECOGNITION (SPR); RHESUS MONKEYS; NERVE AGENTS; SOMAN; BUTYRYLCHOLINESTERASE (BUCHE); COGNITION; BEHAVIOR ID PRIMATES; TOXICITY; ENZYME AB Recently, it has been demonstrated that an exogenously administered enzyme such as butyrylcholinesterase (BuChE) can prevent death in rhesus monkeys exposed to multiple-lethal doses of the acetylcholinesterase inhibitor soman when the enzyme is given prior to soman exposure (3). We report that despite BuChE protecting against soman-induced lethality, behavioral effects are seen in these monkeys which last for at least 6 days as measured by performance on a serial probe recognition (SPR) task. Analyses of the serial position curves showed that performance was lower on the probe trials when the probe items were from the middle of the list than when the probe items were from the beginning or end of the list which were unaffected. BuChE given alone also produced behavioral effects, causing all animals not to respond on the probe trials until 8 h following BuChE administration. Taken together, these findings suggest that the BuChE is not completely binding all of the soman and that a concentration of soman which is capable of causing behavioral effects may be entering the CNS. C1 USA,MED RES INST CHEM DEF,DIV DRUG ASSESSMENT VET MED & LAB RESOURCES,ABERDEEN PROVING GROUND,MD 21010. USA,MED RES INST CHEM DEF,DIV PHARMACOL,ABERDEEN PROVING GROUND,MD 21010. NR 13 TC 18 Z9 18 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0892-0362 J9 NEUROTOXICOL TERATOL JI Neurotoxicol. Teratol. PD MAR-APR PY 1994 VL 16 IS 2 BP 145 EP 148 DI 10.1016/0892-0362(94)90111-2 PG 4 WC Neurosciences; Toxicology SC Neurosciences & Neurology; Toxicology GA NG800 UT WOS:A1994NG80000002 PM 8052188 ER PT J AU SCHOMER, PD WAGNER, LR BENSON, LJ BUCHTA, E HIRSCH, KW KRAHE, D AF SCHOMER, PD WAGNER, LR BENSON, LJ BUCHTA, E HIRSCH, KW KRAHE, D TI HUMAN AND COMMUNITY RESPONSE TO MILITARY SOUNDS - RESULTS FROM FIELD-LABORATORY TESTS OF SMALL-ARMS, TRACKED-VEHICLE, AND BLAST SOUNDS SO NOISE CONTROL ENGINEERING JOURNAL LA English DT Article AB The study reported here utilized paired-comparison tests with listeners in real houses to evaluate human response to test sounds from one of three categories of military sources: (1) small-arms fire, (2) tracked vehicles (tanks and infantry fighting vehicles), and (3) large blasts. The control sound sources were either a wheeled vehicle or white/pink noise. For wheeled-vehicle control sound, the maximum value of the small-arms penalty was of the order of 10 dB for the additional annoyance of the impulsive sound. The tracked-vehicle penalty (with little or no track sound) was small. For the same A-weighted sound exposure level (ASEL) of control sound, the wheeled-vehicles and pink-noise control sounds yielded annoyance-penalty results which differed by about 10 dB. The relationship between the CSEL of a large-amplitude impulsive sound and the ASEL of its equivalently annoying control sound was level dependent with a slope of the order of 1:2; i.e., a 1 dB change in blast-sound CSEL corresponded to about a 2 dB change in the ASEL of the equivalently annoying control sound. Outdoors, the annoyance generated by a large-amplitude impulse sound and its equivalently annoying control sound were equal when the CSEL of the impulse sound and the ASEL of the control sound were each about 100 dB. RP SCHOMER, PD (reprint author), USA,CONSTRUCT ENGN RES LABS,CHAMPAIGN,IL 61826, USA. NR 0 TC 19 Z9 19 U1 0 U2 1 PU INST NOISE CONTROL ENG PI POUGHKEEPSIE PA PO BOX 3206 ARLINGTON BRANCH, POUGHKEEPSIE, NY 12603 SN 0736-2501 J9 NOISE CONTROL ENG JI Noise Control Eng. J. PD MAR-APR PY 1994 VL 42 IS 2 BP 71 EP 84 DI 10.3397/1.2827863 PG 14 WC Acoustics; Engineering, Multidisciplinary SC Acoustics; Engineering GA NF801 UT WOS:A1994NF80100005 ER PT J AU DICILLO, JJ CHEN, CH GARRETT, WR PAYNE, MG TEMPLETON, DW AF DICILLO, JJ CHEN, CH GARRETT, WR PAYNE, MG TEMPLETON, DW TI POTENTIAL EYE AND SENSOR PROTECTION FROM TUNABLE LASERS BY MEANS OF THIN-FILM ALUMINUM MIRRORS SO OPTICAL ENGINEERING LA English DT Article DE LASER BEAM ATTENUATION; LASER ABLATION ID DAMAGE; RADIATION AB An experimental investigation was conducted of the feasibility in using thin film aluminum mirrors as components of an optical system designed to attenuate laser light. When the laser light is focused onto the surface of these mirrors, the aluminum film is vaporized. Using a unique optical geometry, the laser pulse is then returned to the initial damage spot to maximize attenuation. The amount of light that eventually emerges from the optical system is significantly reduced. Results indicate a maximum attenuation of incident light of more than a factor of 10(4). Variations of the principal experiment were performed to optimize results. An explanation of some phenomena involved and possible improvements are discussed. C1 OAK RIDGE NATL LAB,DIV HLTH & SAFETY RES,CHEM PHYS SECT,OAK RIDGE,TN 37830. GEORGIA SO UNIV,DEPT PHYS,STATESBORO,GA 30460. USA,TANK AUTOMOT COMMAND,WARREN,MI 48397. RP DICILLO, JJ (reprint author), UNIV TENNESSEE,DEPT PHYS & ASTRON,KNOXVILLE,TN 37996, USA. NR 22 TC 1 Z9 1 U1 0 U2 0 PU SOC PHOTO-OPT INSTRUM ENG PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 SN 0091-3286 J9 OPT ENG JI Opt. Eng. PD MAR PY 1994 VL 33 IS 3 BP 951 EP 956 DI 10.1117/12.157689 PG 6 WC Optics SC Optics GA NA360 UT WOS:A1994NA36000041 ER PT J AU WACK, RP DEMERS, DM BASS, JW AF WACK, RP DEMERS, DM BASS, JW TI IMMATURE NEUTROPHILS IN THE PERIPHERAL-BLOOD SMEAR OF CHILDREN WITH VIRAL-INFECTIONS SO PEDIATRIC INFECTIOUS DISEASE JOURNAL LA English DT Note DE VIRUS INFECTIONS; BLOOD CELL COUNTS; BAND FORMS ID INFANTS C1 TRIPLER ARMY MED CTR,DEPT PEDIAT,HONOLULU,HI 96859. NR 14 TC 6 Z9 6 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0891-3668 J9 PEDIATR INFECT DIS J JI Pediatr. Infect. Dis. J. PD MAR PY 1994 VL 13 IS 3 BP 228 EP 230 PG 3 WC Immunology; Infectious Diseases; Pediatrics SC Immunology; Infectious Diseases; Pediatrics GA NA577 UT WOS:A1994NA57700012 PM 8177632 ER PT J AU EASA, D MUNDIE, TG FINN, KC HASHIRO, G BALARAMAN, V AF EASA, D MUNDIE, TG FINN, KC HASHIRO, G BALARAMAN, V TI CONTINUOUS NEGATIVE EXTRATHORACIC PRESSURE VERSUS POSITIVE END-EXPIRATORY PRESSURE IN PIGLETS AFTER SALINE LUNG LAVAGE SO PEDIATRIC PULMONOLOGY LA English DT Article DE DYNAMIC LUNG COMPLIANCE; LUNG RESISTANCE; END-EXPIRATORY LUNG VOLUME; CARDIAC OUTPUT; TRANSMURAL VASCULAR RESISTANCE; PULMONARY-SYSTEMIC VASCULAR RESISTANCE; BLOOD GASES ID RESPIRATORY-DISTRESS SYNDROME; AIRWAY PRESSURE; VENTILATION; INFANTS; RABBITS; INJURY; MODEL AB Recent reports have suggested that substituting continuous negative extrathoracic pressure (CNEP) for positive end-expiratory pressure (PEEP) may result in clinical benefits to infants with pulmonary disease. Other studies have suggested potential hemodynamic advantages. We compared the effects of CNEP and PEEP in 13 mechanically ventilated newborn piglets after acute lung injury induced by saline lavage. The piglets were instrumented, saline-lavaged, and exposed to 15 minute periods of incremental CNEP (-3, -6, -9, -12 cmH(2)O) (n = 7) or PEEP (3, 6, 9, 12 cmH(2)O) (n = 6). We measured and/or calculated dynamic lung compliance (C-Ldyn), lung resistance (R(L)), end-expiratory lung volume (EELV), blood gases, cardiac output (CO), heart rate (HR), transmural vascular pressures, and pulmonary and systemic vascular resistance. Pulmonary function abnormalities after saline lavage included decreased P-aO2, C-Ldyn, EELV, and increased P-aCO2 and R(L) (P < 0.05). Except for decreased CO, lung inflation with both CNEP and PEEP resulted in large increases in P-aO2 without major pulmonary or hemodynamic effects. Other than differences in EELV at 3, 6 and 9 cmH(2)O distending pressure, there were no differences in pulmonary function or hemodynamics between sequences of incremental CNEP and PEEP. We conclude that CNEP and PEEP are physiologically equivalent in this model of acute lung injury. (C) 1994 Wiley-Liss, Inc. C1 TRIPLER ARMY MED CTR,DEPT CLIN INVEST,HONOLULU,HI 96859. RP EASA, D (reprint author), JOHN BURNS SCH MED,KAPIOLANI MED CTR WOMEN CHILDREN,DEPT PEDIAT,1319 PUNAHOU ST,HONOLULU,HI 96826, USA. NR 19 TC 16 Z9 16 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 8755-6863 J9 PEDIATR PULM JI Pediatr. Pulmonol. PD MAR PY 1994 VL 17 IS 3 BP 161 EP 168 DI 10.1002/ppul.1950170305 PG 8 WC Pediatrics; Respiratory System SC Pediatrics; Respiratory System GA MY963 UT WOS:A1994MY96300004 PM 8196996 ER PT J AU ELSTON, DM BERGFELD, WF AF ELSTON, DM BERGFELD, WF TI SKIN DISEASES OF THE HANDS AND FEET SO PHYSICIAN AND SPORTSMEDICINE LA English DT Article AB A variety of dermatologic problems affect the hands and feet of active patients, often producing significant pain and disability. Traumatic disorders include friction blisters, calcaneal petechiae, subungual hemorrhage, and piezogenic papules. Infectious disorders include hot tub follicultis, swimming pool granuloma, tinea pedis, warts, and herpetic whitlow. Athletic shoe dermatitis is a common allergic disorder, and hand eczema is a common disorder with a strong hereditary component. Prompt diagnosis and treatment can minimize morbidity. Some traumatic disorders can be prevented. RP ELSTON, DM (reprint author), BROOKE ARMY MED CTR,DERMATOL SERV,FT SAM HOUSTON,TX 78234, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MCGRAW HILL HEALTHCARE PUBLICATIONS PI MINNEAPOLIS PA 4530 WEST 77TH ST, MINNEAPOLIS, MN 55435-5000 SN 0091-3847 J9 PHYSICIAN SPORTSMED JI Physician Sportsmed. PD MAR PY 1994 VL 22 IS 3 BP 40 EP & PG 0 WC Primary Health Care; Orthopedics; Sport Sciences SC General & Internal Medicine; Orthopedics; Sport Sciences GA MY467 UT WOS:A1994MY46700008 PM 27425231 ER PT J AU SEAMAN, RL BEBLO, DA RASLEAR, TG AF SEAMAN, RL BEBLO, DA RASLEAR, TG TI MODIFICATION OF ACOUSTIC AND TACTILE STARTLE BY SINGLE MICROWAVE PULSES SO PHYSIOLOGY & BEHAVIOR LA English DT Article DE ACOUSTIC STARTLE; TACTILE STARTLE; MICROWAVE PULSE; PRESTIMULUS; LEAD TIME; INHIBITION; ENHANCEMENT; RESPONSE AMPLITUDE; RESPONSE LATENCY ID REFLEX MODIFICATION; RATS; STIMULI; RESPONSES; BEHAVIOR; INHIBITION; SYSTEMS; DOMAIN; ONSET AB Modification of acoustic and tactile startle by single microwave pulses. PHYSIOL BEHAV 55(3) 587-595, 1994.-Single microwave pulses at 1.25 GHz were delivered to the head and neck of male Long-Evans rats as a prestimulus to acoustic and tactile startle. For acoustic startle, pulses averaging 0.96 mu s in duration were tested with two specific absorption rate (specific absorption) ranges, 15.0-30.0 kW/kg (16.0-44.2 mJ/kg) and 35.5-86.0 kW/kg (66.6-141.8 mJ/kg), delivered 201, 101, 51, 3, and 1 ms before and 1 ms after onset of a startling noise. The low-intensity pulse did not affect peak amplitude, integral, or latency of the whole-body startle response. The high-intensity pulse at 101 and 51 ms inhibited the startle response by decreasing peak amplitude and integral; at 201 and 51 ms latency was increased. The high-intensity pulse at 1 ms enhanced the startle response by increasing peak amplitude and at 3 ms by increasing integral. For tactile startle, either microwave pulses averaging 7.82 mu s in duration and 55.9-113.3 kW/kg (525.0-1055.7 mJ/kg) or 94 dB SPL clicks were delivered 157, 107, 57, and 7 ms before and 43 ms after onset of a startling air burst. The microwave pulse at 57 ms inhibited the startle response by decreasing peak amplitude; at 157, 107, 57, and 7 ms it increased latency. The microwave pulse at 43 ms after onset enhanced the startle response by increasing peak amplitude. The acoustic click at 157 and 57 ms inhibited the startle response by decreasing peak amplitude; at 157, 107, and 57 ms it increased latency. The microwave pulse inhibition and enhancement of startle were similar to previously reported effects of sensory stimuli delivered at similar lead times, indicating the possibility that action was mediated by sensory stimulation. C1 ERC BIOSERV CORP,GAITHERSBURG,MD 20879. WALTER REED ARMY INST RES,WASHINGTON,DC 20307. RP SEAMAN, RL (reprint author), LOUISIANA TECH UNIV,DEPT BIOMED ENGN,POB 3185,RUSTON,LA 71272, USA. NR 54 TC 4 Z9 4 U1 0 U2 2 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0031-9384 J9 PHYSIOL BEHAV JI Physiol. Behav. PD MAR PY 1994 VL 55 IS 3 BP 587 EP 595 DI 10.1016/0031-9384(94)90121-X PG 9 WC Psychology, Biological; Behavioral Sciences SC Psychology; Behavioral Sciences GA MY684 UT WOS:A1994MY68400031 PM 8190781 ER PT J AU DURI, ZJ SCOVILL, JP HUGGINS, JW AF DURI, ZJ SCOVILL, JP HUGGINS, JW TI ACTIVITY OF A METHANOLIC EXTRACT OF ZIMBABWEAN CRINUM-MACOWANII AGAINST EXOTIC RNA VIRUSES IN-VITRO SO PHYTOTHERAPY RESEARCH LA English DT Note DE CRINUM-MACOWANII; YELLOW FEVER VIRUS; JAPANESE ENCEPHALITIS VIRUS; PUNTA-TORO VIRUS; VENEZUELAN EQUINE ENCEPHALITIS VIRUS ID ANTINEOPLASTIC AGENTS AB The in vitro antiviral activity of a freeze-dried methanolic extract of the bulbs of Zimbabwean Crinum macowanii was determined in Vero cells infected with a number of exotic RNA viruses. At a concentration of 32 mug/mL, the crude methanolic extract reduced by 100% the viral cytopathic effect in Vero cells infected with yellow fever virus, and caused a 70% inhibition of the viral cytopathic effect in cells infected with Japanese encephalitis virus. No evidence of cytotoxicity was observed at this concentration. The freeze-dried extract inhibited the replication of the above mentioned viruses by 100% at a concentration of 10 mug/mL. No cytotoxicity was seen at this concentration. C1 USA,MED RES INST INFECT DIS,DIV TOXICOL,FREDERICK,MD 21702. USA,MED RES INST INFECT DIS,DIV VIROL,FREDERICK,MD 21702. UNIV ZIMBABWE,DEPT CHEM,HARARE,ZIMBABWE. NR 6 TC 10 Z9 10 U1 0 U2 1 PU JOHN WILEY & SONS LTD PI W SUSSEX PA BAFFINS LANE CHICHESTER, W SUSSEX, ENGLAND PO19 1UD SN 0951-418X J9 PHYTOTHER RES JI Phytother. Res. PD MAR PY 1994 VL 8 IS 2 BP 121 EP 122 DI 10.1002/ptr.2650080217 PG 2 WC Chemistry, Medicinal; Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA ND078 UT WOS:A1994ND07800016 ER PT J AU MCMANUS, AT MCMANUS, WF MASON, AD PRUITT, BA AF MCMANUS, AT MCMANUS, WF MASON, AD PRUITT, BA TI BETA-HEMOLYTIC STREPTOCOCCAL BURN WOUND INFECTIONS ARE TOO INFREQUENT TO JUSTIFY PENICILLIN PROPHYLAXIS SO PLASTIC AND RECONSTRUCTIVE SURGERY LA English DT Letter RP MCMANUS, AT (reprint author), USA,INST SURG RES,FT SAM HOUSTON,TX 78234, USA. NR 0 TC 4 Z9 4 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0032-1052 J9 PLAST RECONSTR SURG JI Plast. Reconstr. Surg. PD MAR PY 1994 VL 93 IS 3 BP 650 EP 650 PG 1 WC Surgery SC Surgery GA MZ506 UT WOS:A1994MZ50600045 PM 8115533 ER PT J AU LAURIE, CD AF LAURIE, CD TI THE SAUERKRAUTS - GERMAN PRIONERS-OF-WAR AS OSS AGENTS, 1944-1945 SO PROLOGUE-QUARTERLY OF THE NATIONAL ARCHIVES LA English DT Article RP LAURIE, CD (reprint author), US ARMY CTR MILITARY HIST,WASHINGTON,DC, USA. NR 12 TC 2 Z9 2 U1 0 U2 0 PU NATL ARCHIVES TRUST FUND BOARD PI WASHINGTON PA WASHINGTON, DC 20408 SN 0033-1031 J9 PROLOGUE JI Prologue-Q. Natl. Archives PD SPR PY 1994 VL 26 IS 1 BP 49 EP 61 PG 13 WC History SC History GA ND343 UT WOS:A1994ND34300005 ER PT J AU FINE, BJ KOBRICK, JL LIEBERMAN, HR MARLOWE, B RILEY, RH THARION, WJ AF FINE, BJ KOBRICK, JL LIEBERMAN, HR MARLOWE, B RILEY, RH THARION, WJ TI EFFECTS OF CAFFEINE OR DIPHENHYDRAMINE ON VISUAL VIGILANCE SO PSYCHOPHARMACOLOGY LA English DT Article DE VIGILANCE; RESPONSE TIME; CAFFEINE; DIPHENHYDRAMINE; HUMAN PERFORMANCE; VISUAL PERCEPTION; MOOD ID HUMAN-PERFORMANCE; COMBINATION; CONSUMPTION; DIAZEPAM; ALCOHOL; MOOD AB The effects of two drugs having opposite effects on the central nervous system were investigated using a newly developed visual vigilance task. Twenty-four male volunteers (median age = 20) performed the task on three separate occasions; after consuming placebo, caffeine (200 mg), or diphenhydramine (25 mg), in a double-blind, Latin Square design. At least 2 days intervened between drug administrations. Caffeine use was restricted for 10 h and smoking for 3h before drug administration. When compared with placebo, caffeine significantly increased the number of correct responses and decreased response times, whereas diphenhydramine decreased the number of correct responses and increased response times. Low habitual consumers of caffeine (<100 mg/day) and nonsmokers had more correct responses than did high habitual caffeine consumers (>100 mg/day) and smokers, but only in the placebo condition. Non-smokers had faster response times than smokers only in the placebo condition. Both caffeine and diphenhydramine altered certain aspects of mood. C1 USA,INST ENVIRONM MED,NATICK,MA 01760. GEOCENTERS INC,NEWTON,MA. NR 35 TC 63 Z9 65 U1 2 U2 10 PU SPRINGER VERLAG PI NEW YORK PA 175 FIFTH AVE, NEW YORK, NY 10010 SN 0033-3158 J9 PSYCHOPHARMACOLOGY JI Psychopharmacology PD MAR PY 1994 VL 114 IS 2 BP 233 EP 238 DI 10.1007/BF02244842 PG 6 WC Neurosciences; Pharmacology & Pharmacy; Psychiatry SC Neurosciences & Neurology; Pharmacology & Pharmacy; Psychiatry GA NA384 UT WOS:A1994NA38400007 PM 7838913 ER PT J AU DENAMOR, AFD CABALEIRO, MC VUANO, BM SALOMON, M PIERONI, OI TANAKA, DAP NG, CY TANCO, MAL RODRIGUEZ, NM GARCIA, JDC CASAL, AR AF DENAMOR, AFD CABALEIRO, MC VUANO, BM SALOMON, M PIERONI, OI TANAKA, DAP NG, CY TANCO, MAL RODRIGUEZ, NM GARCIA, JDC CASAL, AR TI THERMODYNAMIC AND ELECTROCHEMICAL ASPECTS OF THE INTERACTIONS OF FUNCTIONALIZED CALIX(4)ARENES AND METAL-CATIONS IN ALLOSTERIC MEDIA SO PURE AND APPLIED CHEMISTRY LA English DT Article; Proceedings Paper CT International Conference on Thermodynamics of Solutions and Biological Systems CY JAN 03-06, 1993 CL NEW DELHI, INDIA SP INT UNION PURE & APPL CHEM, PHYS CHEM DIV, INDIAN NATL SCI ACAD, INDIAN INST TECHNOL, NEW DELHI & PANJAB UNIV ID RAY CRYSTAL-STRUCTURES; MOLECULAR RECEPTORS; N,N-DIMETHYLFORMAMIDE; ACETONITRILE; CALIXARENES; COMPLEXES; WATER AB To gain an understanding of the various factors which are likely to contribute to the overall extraction of metal cations by alkyl p-tert-butylcalix(4)arene esters, different approaches are considered. Thus, ligand-solvent interactions are detected from transfer enthalpies of calixarene esters in the appropriate solvents obtained calorimetrically. Conductance measurements are used to determine stability constants of metal cations and these ligands and ion-pair formations for the single and complexed electrolytes with the anion in the non-aqueous medium. Thermodynamic data (free energies, enthalpies and entropies) of complexation involving calixarene esters are for the first time derived from titration microcalorimetry and some representative data are reported. The extraction of metal cations from aqueous solutions by water insoluble calixarene esters is discussed. C1 UNIV NACL LA SUR,AREA QUIM ANAL,RA-8000 BAHIA BLANCA,ARGENTINA. USA,ETDL LABCOM,POWER SOURCES LAB,FT MONMOUTH,NJ 07703. RP DENAMOR, AFD (reprint author), UNIV SURREY,DEPT CHEM,THERMOCHEM LAB,GUILDFORD GU2 5XH,SURREY,ENGLAND. RI Pacheco Tanaka, David Alfredo/P-3947-2014 OI Pacheco Tanaka, David Alfredo/0000-0003-0767-1141 NR 17 TC 17 Z9 17 U1 0 U2 1 PU BLACKWELL SCIENCE LTD PI OXFORD PA OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL SN 0033-4545 J9 PURE APPL CHEM JI Pure Appl. Chem. PD MAR PY 1994 VL 66 IS 3 BP 435 EP 440 DI 10.1351/pac199466030435 PG 6 WC Chemistry, Multidisciplinary SC Chemistry GA NL198 UT WOS:A1994NL19800012 ER PT J AU DURIG, JR KIM, YH GUIRGIS, GA MCDONALD, JK AF DURIG, JR KIM, YH GUIRGIS, GA MCDONALD, JK TI FT-RAMAN AND INFRARED-SPECTRA, R(0) STRUCTURAL PARAMETERS, AB-INITIO CALCULATIONS AND VIBRATIONAL ASSIGNMENT FOR NITRYL CHLORIDE SO SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY LA English DT Article ID QUADRUPOLE COUPLING-CONSTANTS; MOLECULAR-STRUCTURE; MICROWAVE-SPECTRUM; NITROSYL CHLORIDE; TRICHLORIDE; V2 AB The FT-Raman spectra (2000-30 cm-1) of liquid and solid nitryl chloride, ClNO2, along with the infrared spectra (2000-80 cm-1) of the gas and solid have been recorded. All six fundamentals are confidently identified and the potential energy distributions determined from the force fields obtained from ab initio calculations. Several different basis sets have been utilized to determine the harmonic frequencies and force constants which are compared to the previously reported valence force constants. Structural parameters have been calculated with these basis sets including electron correlation with MP2, MP3 and MP4 perturbation. The calculated equilibrium structural parameters are compared to the experimental r0 structural parameters. The spectra of the solid indicate that there are at least two molecules per primitive cell. All of these results are compared to the corresponding quantities for some similar molecules. C1 USA,MISSILE COMMAND,CTR RES DEV & ENGN,AMSMI RD WS CM,WEAPONS SCI DIRECTORATE,REDSTONE ARSENAL,AL 35898. MILES INC,ANALYT RES LAB,DIV DYES PIGMENTS & ORGAN,CHARLESTON,SC 29411. RP DURIG, JR (reprint author), UNIV S CAROLINA,DEPT CHEM & BIOCHEM,COLUMBIA,SC 29208, USA. NR 27 TC 12 Z9 12 U1 1 U2 6 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0584-8539 J9 SPECTROCHIM ACTA A JI Spectroc. Acta Pt. A-Molec. Biomolec. Spectr. PD MAR PY 1994 VL 50 IS 3 BP 463 EP 472 DI 10.1016/0584-8539(94)80161-4 PG 10 WC Spectroscopy SC Spectroscopy GA MY464 UT WOS:A1994MY46400006 ER PT J AU WATT, G SMITH, CD KAEWSUPO, A DAVIS, TME AF WATT, G SMITH, CD KAEWSUPO, A DAVIS, TME TI 3,4-DIAMINOPYRIDINE REVERSES RESPIRATORY PARALYSIS INDUCED BY A PRESYNAPTICALLY ACTIVE SNAKE-VENOM AND ITS MAJOR NEUROTOXIN SO TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID TRANSMITTER RELEASE; PHOSPHOLIPASE-A2 NEUROTOXINS; NAJA-NAJA; THAILAND; 4-AMINOPYRIDINE; BITES AB Presynaptically active snake venom neurotoxins induce a potentially fatal neuromuscular blockade which cannot be reliably overcome by current therapy. The drug 3,4-diaminopyridine (DAP) is effective in other presynaptic paralytic conditions and was therefore tried in anaesthetized rabbits with respiratory paralysis induced by krait (Bungarus fasciatus) venom. A strain gauge pneumograph measured rabbit chest circumference during the respiratory cycle to document objectively effects of toxins and treatments. DAP counteracted the effects of both whole krait venom and its purified presynaptically active component, beta-bungarotoxin. Respiratory excursions increased within 4-8 min after DAP injection in animals paralysed with beta-bungarotoxin and 4-10 min after the injection of DAP in animals paralysed with 1 mg/kg whole krait venom. The onset of complete respiratory paralysis after a lethal dose of whole krait venom (2 mg/kg) was delayed significantly by DAP. This is the first indication that presynaptic venom paralysis can be reversed and suggests that DAP merits further evaluation as treatment for this condition. C1 ARMED FORCES RES INST MED SCI,DEPT MED,BANGKOK 10400,THAILAND. ARMED FORCES RES INST MED SCI,DEPT VET MED,BANGKOK 10400,THAILAND. MAHIDOL UNIV,FAC TROP MED,BANGKOK 10400,THAILAND. RI Davis, Timothy/M-5144-2014 NR 22 TC 2 Z9 2 U1 0 U2 0 PU ROYAL SOC TROPICAL MEDICINE PI LONDON PA MANSON HOUSE 26 PORTLAND PLACE, LONDON, ENGLAND W1N 4EY SN 0035-9203 J9 T ROY SOC TROP MED H JI Trans. Roy. Soc. Trop. Med. Hyg. PD MAR-APR PY 1994 VL 88 IS 2 BP 243 EP 246 DI 10.1016/0035-9203(94)90316-6 PG 4 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA NL591 UT WOS:A1994NL59100043 PM 8036689 ER PT J AU GRIFFIN, GD LIPPERT, LE DOW, NS BERGER, TA HICKMAN, MR SALATA, KF AF GRIFFIN, GD LIPPERT, LE DOW, NS BERGER, TA HICKMAN, MR SALATA, KF TI A FLOW CYTOMETRIC METHOD FOR PHENOTYPING RECIPIENT RED-CELLS FOLLOWING TRANSFUSION SO TRANSFUSION LA English DT Article ID SURVIVAL AB Background: Reticulocyte phenotyping is used for transfused patients, who have red cell antibodies, to match blood for subsequent transfusion. Current methods are labor-intensive and require a significant amount of sample. Study Design and Methods: A simple dual-color flow cytometry method developed for antigen typing of reticulocytes in mixed red cell populations is reported. Antigens were labeled by an indirect immunofluorescence technique using undiluted reagent sera as the primary label, biotinylated goat anti-human IgG as the secondary label, and avidin-phycoerythrin as the fluorescent stain. Reticulocytes were labeled with a thiazole orange fluorescent stain. Reticulocyte identification and antigen typing were performed on 319 samples to establish the validity of the procedure. Mixed red cells were prepared in all possible c antigen combinations to simulate transfusion concentrations of 25, 50, and 75 percent. Results: The anti-c flow cytometry profiles readily distinguished between antigen-positive and antigen-negative populations and allowed the detection of reticulocytes at all simulated transfusion concentrations. Similar results were obtained in experiments using C, K, s, Fy(a), Fy(b), Jk(a), or Jk(b) sera against equal volumes of antigen-positive and -negative cells. Anti-S gave inconsistent results. The in vitro results were confirmed in 19 transfused patients who had received red cells antigenically different from their own as well as cells from 1 chimera blood donor. Conclusion: This method provides a simpler, safer, less labor-intensive, and less subjective technique requiring far less sample volume than current methods for antigen typing of reticulocytes in mixed red cell samples from recently transfused patients. C1 WALTER REED ARMY MED CTR,DEPT CLIN INVEST,ALLERGY IMMUNOL RES LAB,6825 16TH ST NW,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,DEPT PATHOL,DIAGNOST IMMUNOL LAB,WASHINGTON,DC 20307. NR 23 TC 24 Z9 24 U1 0 U2 1 PU AMER ASSOC BLOOD BANKS PI BETHESDA PA 8101 GLENBROOK RD, BETHESDA, MD 20814-2749 SN 0041-1132 J9 TRANSFUSION JI Transfusion PD MAR PY 1994 VL 34 IS 3 BP 233 EP 237 DI 10.1046/j.1537-2995.1994.34394196621.x PG 5 WC Hematology SC Hematology GA ND081 UT WOS:A1994ND08100009 PM 8146896 ER PT J AU FOSDICK, R ZHANG, Y AF FOSDICK, R ZHANG, Y TI COEXISTENT PHASE MIXTURES IN THE ANTIPLANE SHEAR OF AN ELASTIC TUBE SO ZEITSCHRIFT FUR ANGEWANDTE MATHEMATIK UND PHYSIK LA English DT Article AB We study the detailed structure of the deformed configuration of an elastic tube whose cross section is a convex ring that is subjected to a prescribed relative axial displacement of its lateral boundaries. The material is assumed to have a non-convex stored energy function. Special attention is paid to the situation when there is no minimizer of the associated anti-plane shear minimization problem, but, nevertheless, the energy functional has an infimum. The non-existence of a minimizer to this problem for a certain interval of prescribed relative axial displacement of the lateral boundaries implies that among all ''admissible'' deformations there is none with this boundary data for which the values of the stored energy function correspond to its convex points almost everywhere in the body. Because of this, we find that to reach the infimum the tube divides into three subdomains: one of high strain, one of low strain, and one of intermediate ''mixed'' strain. In the intermediate ''mixed'' strain subdomain, the field values of the stored energy correspond to convex combinations of convex, but not strictly convex, points of the stored energy function. The main variational problem then gives rise to a free boundary problem in which the subdomain where the strict convexity of the stored energy function breaks down must be determined as part of the solution. The characterization of this intermediate phase mixture region is one of the goals of this work. RP FOSDICK, R (reprint author), UNIV MINNESOTA,ARMY HIGH PERFORMANCE COMP RES CTR,MINNEAPOLIS,MN 55455, USA. NR 11 TC 10 Z9 10 U1 0 U2 0 PU BIRKHAUSER VERLAG AG PI BASEL PA PO BOX 133 KLOSTERBERG 23, CH-4010 BASEL, SWITZERLAND SN 0044-2275 J9 Z ANGEW MATH PHYS JI Z. Angew. Math. Phys. PD MAR PY 1994 VL 45 IS 2 BP 202 EP 244 DI 10.1007/BF00943502 PG 43 WC Mathematics, Applied SC Mathematics GA NG133 UT WOS:A1994NG13300002 ER PT J AU SCHAUER, SN FLEMISH, JR WITTSTRUCK, R LANDSTRASS, MI PLANO, MA AF SCHAUER, SN FLEMISH, JR WITTSTRUCK, R LANDSTRASS, MI PLANO, MA TI PHOSPHORUS INCORPORATION IN PLASMA-DEPOSITED DIAMOND FILMS SO APPLIED PHYSICS LETTERS LA English DT Article ID DOPED DIAMOND; POLYCRYSTALLINE DIAMOND; DEVICE APPLICATIONS; EPITAXIAL-FILMS; MICROWAVE AB Phosphorus-doped polycrystalline and homoepitaxial diamond films were grown using both microwave and dc plasma assisted chemical vapor deposition. P incorporation was quantified using secondary ion mass spectrometry, and was approximately ten times greater for polycrystalline films deposited using dc plasmas compared to microwave plasmas. For microwave-assisted growth, P incorporation was approximately ten times greater in polycrystalline than homoepitaxial films. These effects appear to be due to preferential incorporation at grain boundaries, since higher levels of P are measured in samples with smaller grains. The films were highly electrically resistive, with conductivities of 10(-10)-10(-9)/OMEGA cm at room temperature. C1 USA,RES LAB,FT MONMOUTH,NJ 07703. CRYSTALLUME,MENLO PK,CA 94025. NR 16 TC 25 Z9 25 U1 0 U2 1 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD FEB 28 PY 1994 VL 64 IS 9 BP 1094 EP 1096 DI 10.1063/1.110943 PG 3 WC Physics, Applied SC Physics GA MZ337 UT WOS:A1994MZ33700013 ER PT J AU JOHN, TR SMITH, LA KAISER, II AF JOHN, TR SMITH, LA KAISER, II TI GENOMIC SEQUENCES ENCODING THE ACIDIC AND BASIC SUBUNITS OF MOJAVE TOXIN - UNUSUALLY HIGH SEQUENCE IDENTITY OF NONCODING REGIONS SO GENE LA English DT Note DE CROTALUS SCUTULATUS SCUTULATUS; MOJAVE RATTLESNAKE; RECOMBINANT DNA; CLONING; RATTLESNAKE; EVOLUTION; EXON/INTRON ARRANGEMENT; NEUROTOXINS; PHOSPHOLIPASE A(2) ID PANCREATIC PHOSPHOLIPASE-A2; SNAKE-VENOM; 2 SUBUNITS; CROTOXIN; GENE; CDNAS; CONSERVATION; INTRON; CLONING; DNA AB Mojave toxin (Mtx) is a heterodimeric, neurotoxic phospholipase A(2) (PLA(2)) found in the venom of the Mojave rattlesnake, Crotalus scutulatus scutulatus, and is characteristic of all rattlesnake presynaptic neurotoxins. This paper describes the isolation and nucleotide (nt) sequence of the genomic clones encoding both the non-neurotoxic, nonenzymatic acidic subunit (Mtx-a) and the toxic, PLA(2)-active basic subunit (Mtx-b), and compares their structures. Both cloned genes shared virtually identical overall organization, with four exons separated by three introns, which were inserted in the same relative positions of the genes' coding regions. The exon/intron structure was similar to that reported for mammalian PLA(2) genes. Most remarkable was the high degree of nt sequence identity between Mtx-a and Mtx-b. While the exons shared about 70% identity, the introns were greater than 90% identical and the 5' and 3' untranslated and flanking regions were greater than 95% identical. These findings support our earlier suggestion [Aird et al., Biochemistry 24 (1985) 7054-7058] that the genes coding for the two subunits arose from a common ancestor. There has clearly been a strong selection on the nt sequence of the non-coding regions during this evolutionary process. This is the first report of genomic sequences of PLA(2)-like proteins from snakes. C1 UNIV WYOMING,DEPT MOLEC BIOL,LARAMIE,WY 82071. USA,MED RES INST INFECT DIS,DIV TOXICOL,FREDERICK,MD 21702. NR 31 TC 70 Z9 72 U1 0 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0378-1119 J9 GENE JI Gene PD FEB 25 PY 1994 VL 139 IS 2 BP 229 EP 234 DI 10.1016/0378-1119(94)90761-7 PG 6 WC Genetics & Heredity SC Genetics & Heredity GA NA749 UT WOS:A1994NA74900015 PM 8112610 ER PT J AU JENKINS, TF WALSH, ME AF JENKINS, TF WALSH, ME TI INSTABILITY OF TETRYL TO SOXHLET EXTRACTION SO JOURNAL OF CHROMATOGRAPHY A LA English DT Note ID LIQUID-CHROMATOGRAPHIC METHOD; RESIDUES; SOIL AB The stability of tetryl (N-methyl-N,2,4,6-tetranitroaniline) to Soxhlet extraction with methanol was examined by refluxing tetryl in methanol and extracting a tetryl-contaminated soil using Soxhlet, ultrasonic bath and wrist-action shaker methods. The results indicate that tetryl is unstable to Soxhlet extraction. If wet soils are Soxhlet-extracted with methanol, tetryl hydrolyzes to N-methylpicramide (N-methyl-2,4,6-trinitroaniline). If extracted dry, methanolysis products are formed. Ultrasonic bath extraction with acetonitrile is recommended instead. RP JENKINS, TF (reprint author), USA,COLD REG RES & ENGN LAB,HANOVER,NH 03755, USA. NR 24 TC 1 Z9 1 U1 0 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0021-9673 J9 J CHROMATOGR A JI J. Chromatogr. A PD FEB 18 PY 1994 VL 662 IS 1 BP 178 EP 184 DI 10.1016/0021-9673(94)85308-8 PG 7 WC Biochemical Research Methods; Chemistry, Analytical SC Biochemistry & Molecular Biology; Chemistry GA MY330 UT WOS:A1994MY33000019 ER PT J AU SANDS, L RUTHERFORD, GW HOFFMAN, RE SFAKIANAKI, E HOPKINS, RS PEROTTO, R FLEISSNER, ML ALFANO, D MCFARLAND, L OSTERHOLM, MT DAMROW, TA DISALVO, A SEWELL, CM SHIRELEY, LA FLEMING, D SENGER, KA SIMPSON, DM AF SANDS, L RUTHERFORD, GW HOFFMAN, RE SFAKIANAKI, E HOPKINS, RS PEROTTO, R FLEISSNER, ML ALFANO, D MCFARLAND, L OSTERHOLM, MT DAMROW, TA DISALVO, A SEWELL, CM SHIRELEY, LA FLEMING, D SENGER, KA SIMPSON, DM TI HANTAVIRUS PULMONARY SYNDROME, UNITED-STATES 1993 (REPRINTED FROM MMWR, PG 43, 1994) SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Reprint C1 CALIF DEPT HLTH SERV,BERKELEY,CA 94704. COLORADO DEPT HLTH,DENVER,CO. FLORIDA DEPT H & REHABIL SERV,TALLAHASSEE,FL. IDAHO DEPT HLTH & WELFARE,DIV HLTH,BOISE,ID. INDIANA STATE DEPT HLTH,INDIANAPOLIS,IN. KANSAS DEPT HLTH & ENVIRONM,TOPEKA,KS. LOUISIANA DEPT HLTH & HOSP,OFF PUBL HLTH,BATON ROUGE,LA. MINNESOTA DEPT HLTH,MINNEAPOLIS,MN. MONTANA STATE DEPT HLTH & ENVIRONM SCI,HELENA,MT. NEVADA STATE DEPT HUMAN RESOURCES,CARSON CITY,NV. NEW MEXICO DEPT HLTH,SANTA FE,NM. N DAKOTA STATE DEPT HLTH & CONSOLIDATED LABS,BISMARCK,ND. OREGON DEPT HUMAN RESOURCES,STATE HLTH DIV,PORTLAND,OR. S DAKOTA STATE DEPT HLTH,PIERRE,SD. TEXAS DEPT HLTH,AUSTIN,TX. USA,MED RES INST INFECT DIS,FREDERICK,MD 21701. CDC,NATL CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,SPECIAL PATHOGENS BRANCH,ATLANTA,GA. RP SANDS, L (reprint author), ARIZONA DEPT HLTH SERV,PHOENIX,AZ 85007, USA. NR 11 TC 0 Z9 0 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD FEB 16 PY 1994 VL 271 IS 7 BP 498 EP 498 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA MV423 UT WOS:A1994MV42300012 ER PT J AU SHMUKLARSKY, MJ BOUDREAU, EF PANG, LW SMITH, JI SCHNEIDER, I FLECKENSTEIN, L ABDELRAHIM, MM CANFIELD, CJ SCHUSTER, B AF SHMUKLARSKY, MJ BOUDREAU, EF PANG, LW SMITH, JI SCHNEIDER, I FLECKENSTEIN, L ABDELRAHIM, MM CANFIELD, CJ SCHUSTER, B TI FAILURE OF DOXYCYCLINE AS A CAUSAL PROPHYLACTIC AGENT AGAINST PLASMODIUM-FALCIPARUM MALARIA IN HEALTHY NONIMMUNE VOLUNTEERS SO ANNALS OF INTERNAL MEDICINE LA English DT Article DE DOXYCYCLINE; PLASMODIUM-FALCIPARUM; MALARIA, FALCIPARUM; TRAVEL; ANTIMALARIALS ID PYRIMETHAMINE-SULFADOXINE FANSIDAR; RESISTANT MALARIA; AMERICAN TRAVELERS; MEFLOQUINE; AFRICA; THAILAND; VACCINE; SAFETY AB Objective: To determine whether doxycycline, 100 mg administered as a single daily oral dose, is effective as a causal prophylactic agent, an agent active against the pre-erythrocytic liver stage of Plasmodium falciparum malaria parasites, in healthy nonimmune persons. If effective, the recommendation by the Centers for Disease Control and Prevention (CDC) that doxycycline be continued for 4 weeks after returning from malaria-endemic areas could be shortened to 1 week. Design: Randomized, double-blind, placebo-controlled trial. Setting: Medical ward at the U.S. Army Research Institute of Infectious Diseases, Fort Detrick, Maryland. Participants: 18 nonimmune, healthy, adult male volunteers, age 21.7 +/- 2.9 (SD) years, were enrolled in two groups, one of 8 persons and one of 10 persons. Six participants,in the first group and 7 in the second group received doxycycline. The remaining participants received placebo. Two volunteers were dropped from the study, leaving 16 participants for analysis. Intervention: Each participant received doxycycline, 100 mg, or placebo in a single daily oral dose starting 3 days before exposure to P. falciparum-infected mosquitoes and ending 6 days after exposure. Measurements: Monitoring for parasitemia, plasma doxycycline concentrations, and mosquitoes' salivary-gland sporozoite grade. Results: 6 of 6 (100% [95% Cl, 54% to 100%]) participants on doxycycline in the first group and 2 of 6 (33% [Cl, 4% to 78%]) in the second group were protected from malaria. No differences were found between protected and nonprotected participants in the doxycycline elimination half-life (T1/2) (20.8 +/- 5.0 h compared with 21.9 +/- 5.2 h), the steady-state average plasma concentration (1626 +/- 469 ng/mL compared with 1698 +/- 651 ng/mL), or other pharmacokinetic parameter estimates. The mean mosquito salivary-gland sporozoite grade was significantly higher (P = 0.02) in protected (3.5 +/- 0.3) than in nonprotected persons (3.1 +/- 0.1). Overall, 8 of 12 persons on doxycycline were protected from malaria, yielding a causal prophylactic efficacy rate of 67% (Cl, 35% to 90%). Conclusions: A dosing regimen of doxycycline, 100 mg once daily, administered as a causal prophylactic agent against P. falciparum malaria in healthy, nonimmune volunteers, had an unacceptably high failure rate. Therefore, the CDC recommendation that doxycycline should be taken daily starting 1 to 2 days before travel, during travel, and for 4 weeks after travel should still be followed. C1 PHARMACEUT SYST INC,GAITHERSBURG,MD 20879. WHO,GENEVA,SWITZERLAND. WALTER REED GEN HOSP,WASHINGTON,DC 20307. USA,MED RES INST INFECT DIS,FT DETRICK,FREDERICK,MD. RP SHMUKLARSKY, MJ (reprint author), WALTER REED ARMY INST RES,DEPT PHARMACOL,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307, USA. OI Fleckenstein, Lawrence/0000-0001-5320-4531 NR 37 TC 35 Z9 36 U1 0 U2 1 PU AMER COLL PHYSICIANS PI PHILADELPHIA PA INDEPENDENCE MALL WEST 6TH AND RACE ST, PHILADELPHIA, PA 19106-1572 SN 0003-4819 J9 ANN INTERN MED JI Ann. Intern. Med. PD FEB 15 PY 1994 VL 120 IS 4 BP 294 EP 299 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA MW103 UT WOS:A1994MW10300006 PM 8291822 ER PT J AU DOWLING, JP SCALORA, M BLOEMER, MJ BOWDEN, CM AF DOWLING, JP SCALORA, M BLOEMER, MJ BOWDEN, CM TI THE PHOTONIC BAND-EDGE LASER - A NEW APPROACH TO GAIN ENHANCEMENT SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID SURFACE-EMITTING LASERS; CAVITY; GAAS AB Near the band edge of a one-dimensional photonic band gap structure the photon group velocity approaches zero. This effect implies an exceedingly long optical path length in the structure. If an active medium is present, the optical path length increase near the photonic band edge can lead to a better than fourfold enhancement of gain. This new effect has important applications to vertical-cavity surface-emitting lasers. RP DOWLING, JP (reprint author), USA MISSLE COMMAND,CTR RES DEV & ENGN,WEAPONS SCI DIRECTORATE,AMSMI RD WS,REDSTONE ARSENAL,AL 35898, USA. RI DOWLING, JONATHAN/L-2749-2013 NR 15 TC 505 Z9 516 U1 4 U2 38 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0021-8979 J9 J APPL PHYS JI J. Appl. Phys. PD FEB 15 PY 1994 VL 75 IS 4 BP 1896 EP 1899 DI 10.1063/1.356336 PG 4 WC Physics, Applied SC Physics GA MX654 UT WOS:A1994MX65400007 ER PT J AU STROSCIO, MA DUTTA, M ZHANG, XQ AF STROSCIO, MA DUTTA, M ZHANG, XQ TI TRANSITIONS BETWEEN GAMMA AND X STATES OF SHORT-PERIOD SUPERLATTICES DRIVEN BY ANTISYMMETRIC INTERFACE PHONONS SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID GAAS/ALAS QUANTUM-WELLS; SEMICONDUCTOR HETEROINTERFACES; MINIBAND STRUCTURE; ENVELOPE FUNCTIONS; HETEROSTRUCTURES; CONNECTION; EXCITON AB Relative transition probability amplitudes for antisymmetric-interface-phonon-assisted GAMMA-X transitions in selected short-period superlattices are estimated by using the dielectric continuum model for antisymmetric interface optical phonons in conjunction with a Kronig-Penney model of the superlattice electronic properties. C1 USA,RES LAB,ELECTR & POWER SOURCES DIRECTORATE,FT MONMOUTH,NJ 07703. DUKE UNIV,DEPT ELECT ENGN,DURHAM,NC 27708. RP STROSCIO, MA (reprint author), USA,RES OFF,POB 12211,RES TRIANGLE PK,NC 27709, USA. NR 24 TC 2 Z9 2 U1 0 U2 0 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0021-8979 J9 J APPL PHYS JI J. Appl. Phys. PD FEB 15 PY 1994 VL 75 IS 4 BP 1977 EP 1981 DI 10.1063/1.356321 PG 5 WC Physics, Applied SC Physics GA MX654 UT WOS:A1994MX65400020 ER PT J AU LEAVITT, RP BRADSHAW, JL PHAM, JT TOBIN, MS AF LEAVITT, RP BRADSHAW, JL PHAM, JT TOBIN, MS TI QUANTITATIVE MODEL FOR PHOTOCURRENT SPECTROSCOPY OF QUANTUM-WELL DIODES INCLUDING TRANSIT-TIME AND BACKGROUND-DOPING EFFECTS SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID ELECTRIC-FIELD; SEMICONDUCTOR SUPERLATTICES; TRANSPORT; SPECTRA AB We present a simple model for photocurrent spectroscopy of quantum-well p-i-n diodes that provides a quantitatively accurate desciption of the dependence of photocurrent on absorption coefficient and applied bias. The model incorporates the transit-time effect described previously [R. P. Leavitt and J L. Bradshaw, Appl. Phys. Lett 59, 2433) (1991)] as a limiting case. It also includes the two major effects of residual background doping in the intrinsic region of the diode: nonuniform electric fields, which affect the transport of carriers, and incomplete depletion at low electric fields, which reduces the amount of photocurrent collected. We show that the background-doping effect alone can mimic the transit-time effects: reduction in the overall carrier collection efficiency, saturation of photocurrent spectral features, and the presence of minima in photocurrent where absorption spectra show maxima. We obtain a closed-form expression for the photocurrent in the general case where both transit-time and background-doping effects are significant. Excellent agreement is obtained between model calculations and experimental room-temperature photocurrent spectra for an 89-period 100-angstrom GaAs/100-angstrom Al0.3Ga0.7As multiple-quantum-well diode, where the background doping density, the effective electron mobility, and the built-in potential are treated as adjustable parameters. The background doping density and the built-in potential obtained from the fit are in excellent agreement with independent measurements. We applied the model to predict the dependence of photocurrent on the intrinsic-region thickness of the diode. We also show a dramatic asymmetry between photocurrent spectra measured with light incident from the front and from the back of the diode, and we discuss the impact of this asymmetry on the performance of self-electro-optic-effect devices. We also find good agreement between the model predictions and the photocurrent results of Whitehead et al. [Appl. Phys. Lett. 52, 345 ( 1988)]. Further, our model qualitatively describes the dependence of the photoluminescence intensity on electric fields in multiple-quantum-well p-i-n diodes. RP LEAVITT, RP (reprint author), USA,RES LAB,2800 POWDER MILL RD,ADELPHI,MD 20783, USA. RI Bradshaw, John/E-8330-2011 NR 16 TC 7 Z9 7 U1 0 U2 3 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0021-8979 J9 J APPL PHYS JI J. Appl. Phys. PD FEB 15 PY 1994 VL 75 IS 4 BP 2215 EP 2226 DI 10.1063/1.356284 PG 12 WC Physics, Applied SC Physics GA MX654 UT WOS:A1994MX65400057 ER PT J AU FROST, AE SEAVER, M RUBEL, GO AF FROST, AE SEAVER, M RUBEL, GO TI DELAYED APPEARANCE OF THE LIQUID-CONDENSED PHASE IN 1-OCTADECANOL FILMS ON LEVITATED WATERDROPS SO JOURNAL OF CHEMICAL PHYSICS LA English DT Article ID OCTADECANOL MONOLAYERS; WIND-TUNNEL; EVAPORATION; KINETICS AB We have observed dramatic delays in the formation of the liquid-condensed phase of 1-octadecanol thin films on the surface of levitated water drops as the drops evaporate into a flowing gas stream. When the aqueous substrate starts with more than 1.0X10(-4) M EU(3+) (EDTA), the liquid-condensed phase of 1-octadecanol appears, as expected, at a surface concentration equivalent to one monolayer. As we reduce the initial EU(3+) (EDTA) content, higher and higher surface concentrations of 1-octadecanol are reached prior to the appearance of the liquid-condensed phase. At initial concentrations of EU(3+) (EDTA) below similar to 4.0X10(-7) M, the average surface concentration at the liquid-condensed phase change exceeds ten monolayers. Light-scattering data attest to the presence of small, <400 nm radius, 1-octadecanol particles initially dispersed throughout the substrate. We demonstrate that these particles are collected by the shrinking drop surface with minimal diffusion of the particles to the surface. C1 USA,ARMAMENT MUNIT & CHEM COMMAND,CTR CHEN RES DEV & ENGN,ABERDEEN PROVING GROUND,MD 21010. RP FROST, AE (reprint author), USN,RES LAB,CODE 5610,WASHINGTON,DC 20375, USA. NR 28 TC 4 Z9 4 U1 0 U2 1 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0021-9606 J9 J CHEM PHYS JI J. Chem. Phys. PD FEB 15 PY 1994 VL 100 IS 4 BP 3268 EP 3275 DI 10.1063/1.466417 PG 8 WC Chemistry, Physical; Physics, Atomic, Molecular & Chemical SC Chemistry; Physics GA MX628 UT WOS:A1994MX62800091 ER PT J AU EVERETT, RA AF EVERETT, RA TI MACROALGAE IN MARINE SOFT-SEDIMENT COMMUNITIES - EFFECTS ON BENTHIC FAUNAL ASSEMBLAGES SO JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY LA English DT Article DE ABUNDANCE; BENTHIC FAUNA; DIVERSITY; MACROALGAE; SOFT SEDIMENT; SUBMERGED AQUATIC VEGETATION ID LOBSTERS PANULIRUS-ARGUS; JUVENILE SPINY LOBSTERS; FEEDING-BEHAVIOR; ZOSTERA-MARINA; FUNCTIONAL-MORPHOLOGY; CHESAPEAKE BAY; SEAGRASS BEDS; MERCENARIA-MERCENARIA; CALLINECTES-SAPIDUS; SEASONAL ABUNDANCE AB Algal removal experiments were conducted in 1984 and 1986 to measure the effects of algal cover on the structure of an intertidal benthic assemblage. Cover by the green alga, Ulva expansa (Setchell) Setchell et Gardner, had no affect on total density or species richness of small fauna, compared to removal plots, during the algal season in either year, although diversity indexes (h' and D) were slightly greater in removal plots. Epifauna had consistantly greater densities in algal plots, while infaunal densities were not different in 1984, and greater in algal plots in 1986. Mobile, sediment-water interface feeding taxa were the numerically dominant infauna, and along with predators, exhibited the same patterns as infauna in general. Sedentary sediment-water interface feeders had lower densities under algal cover, while the density of deep deposit-feeders was not different between treatments. Large bivalves, principally the tellinid Macoma nasuta (Conrad), were significantly reduced by algal cover in both years. Post-algal season samples in the 1986 experiment revealed that after a season of algal cover, the densities of small, mobile, sediment-water interface feeding infauna were significantly greater, and those of sedentary species, particularly bivalves and tubicolous suspension-feeders were significantly lower, in plots which had supported an algal mat. The increased abundance of small deposit-feeding fauna was likely a result of an increase in food resources due to in situ burial and decomposition of macroalgae. These experiments indicate that, like other submerged aquatic vegetation (SAV), macroalgae can play an important functional role in structuring benthic faunal assemblages. However, in contrast to other SAV, the presence of macroalgae, particularly laminar forms such as Ulva, can have a mixed effect on the density of benthic fauna. Mobile sediment-water interface feeding species can have greater densities, while the densities of sedentary species, especially bivalves and tube-dwellers, can be much lower with algal cover. C1 UNIV CALIF BERKELEY, DEPT ZOOL, BERKELEY, CA 95620 USA. USA, BODEGA MARINE LAB, BODEGA BAY, CA 94923 USA. NR 125 TC 84 Z9 87 U1 3 U2 35 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0022-0981 EI 1879-1697 J9 J EXP MAR BIOL ECOL JI J. Exp. Mar. Biol. Ecol. PD FEB 15 PY 1994 VL 175 IS 2 BP 253 EP 274 DI 10.1016/0022-0981(94)90030-2 PG 22 WC Ecology; Marine & Freshwater Biology SC Environmental Sciences & Ecology; Marine & Freshwater Biology GA MZ374 UT WOS:A1994MZ37400009 ER PT J AU PEROVICH, DK AF PEROVICH, DK TI LIGHT-REFLECTION FROM SEA-ICE DURING THE ONSET OF MELT SO JOURNAL OF GEOPHYSICAL RESEARCH-OCEANS LA English DT Article ID OPTICAL-PROPERTIES; SNOW; MODEL; SURFACES; NM AB A knowledge of the reflection of light from a sea ice cover is important for the interpretation of remote sensing imagery at visible and near-infrared wavelengths, for climatological studies involving the energy balance of the polar regions, and for understanding radiative transfer in sea ice. Spectral measurements of albedo, bidirectional reflectance distribution function, and polarized reflectance were made for Arctic sea ice conditions found during the onset of melt. The wavelength region studied was from the visible to the near infrared (400-1000 nm). Results are presented for the five following surface types: (1) dry snow, (2) dry snow with a glazed surface, (3) bare ice, (4) blue ice, and (5) melt pond. Results indicate that spectral albedos decrease at all wavelengths as the melt season progresses and the surface conditions evolve from (1) through (5) and that the decrease is most pronounced at longer wavelengths. Reflectance data suggest that at most angles, reflectance has the same spectral shape as albedo; at 30-degrees zenith, reflectance is for the most part azimuthally isotropic; and at 60-degrees zenith there is a significant specular component at 0-degrees azimuth, especially for the bare ice cases. Light reflected at 60-degrees zenith angle was strongly polarized. In general, light reflected from snow-free ice was more strongly polarized, with the degree of polarization increasing with wavelength. RP PEROVICH, DK (reprint author), USA,COLD REG RES & ENGN LAB,72 LYME RD,HANOVER,NH 03755, USA. NR 25 TC 55 Z9 56 U1 0 U2 2 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 SN 0148-0227 J9 J GEOPHYS RES-OCEANS JI J. Geophys. Res.-Oceans PD FEB 15 PY 1994 VL 99 IS C2 BP 3351 EP 3359 DI 10.1029/93JC03397 PG 9 WC Oceanography SC Oceanography GA MY399 UT WOS:A1994MY39900011 ER PT J AU KOPLOVITZ, I STEWART, JR AF KOPLOVITZ, I STEWART, JR TI A COMPARISON OF THE EFFICACY OF HI6 AND 2-PAM AGAINST SOMAN, TABUN, SARIN, AND VX IN THE RABBIT SO TOXICOLOGY LETTERS LA English DT Article DE OXIME; NERVE AGENT POISONING; EFFICACY; ATROPINE; DIAZEPAM ID HI-6; RODENTS; STAGEWISE; ATROPINE; THERAPY; PAM-2 AB This study compared the efficacy of HI6 and 2-PAM against nerve agent (soman, tabun, sarin, and VX) -induced lethality in the atropinesterase-free rabbits pretreated with vehicle (controls) or pyridostigmine. Treatment was administered at signs or 2 min after agent challenge and consisted of oxime (100 mu mo/kg) + atropine (13 mg/kg) (alone or together with diazepam). Twenty-four-h LD(50) values were calculated for soman- and tabun-intoxicated animals, whereas 24-h survival was noted in animals given 10 LD(50)s of sarin or VX. In pyridostigmine and control rabbits intoxicated with soman and treated with oxime + atropine (alone or together with diazepam), HI6 was 3-5 times more effective than 2-PAM.In contrast, HI6 was less effective than 2-PAM against tabun poisoning. In pyridostigmine-pretreated animals exposed to tabun, efficacy was increased more than 3-fold when compare to tabun-challenged animals treated with atropine + HI6 alone. Both oximes were highly effective against sarin and VX. These findings suggest that HI6 could replace 2-PAM as therapy for nerve agent poisoning, because it is superior to 2-PAM against soman, and when used in pyridostigmine-pretreated animals, it affords excellent protection against all four nerve agents when used in combination with atropine (alone or together with diazepam) therapy. RP KOPLOVITZ, I (reprint author), USA,MED RES INST CHEM DEF,DIV DRUG ASSESSMENT,SGRD UV DB,ABERDEEN PROVING GROUND,MD 21010, USA. NR 17 TC 74 Z9 76 U1 2 U2 7 PU ELSEVIER SCI IRELAND LTD PI CLARE PA CUSTOMER RELATIONS MANAGER, BAY 15, SHANNON INDUSTRIAL ESTATE CO, CLARE, IRELAND SN 0378-4274 J9 TOXICOL LETT JI Toxicol. Lett. PD FEB 15 PY 1994 VL 70 IS 3 BP 269 EP 279 DI 10.1016/0378-4274(94)90121-X PG 11 WC Toxicology SC Toxicology GA MU122 UT WOS:A1994MU12200002 PM 8284794 ER PT J AU HUBER, AE STAYTON, PS VINEY, C KAPLAN, DL AF HUBER, AE STAYTON, PS VINEY, C KAPLAN, DL TI LIQUID CRYSTALLINITY OF A BIOLOGICAL POLYSACCHARIDE - THE LEVAN WATER PHASE-DIAGRAM SO MACROMOLECULES LA English DT Article ID FRUCTANS; BEHAVIOR; SYSTEM AB Boundaries on the phase diagram for aqueous solutions of levan (a branched polymer of fructose) were located quantitatively by transmitted light measurements performed with a UV-visible spectrophotometer. Data were collected in the range 10-70-degrees-C; the minimum concentrations required for separation of a liquid crystalline phase and the minimum concentration required for a fully liquid crystalline solution were identified within this range. The liquid crystalline nature of the anisotropic phase was confirmed by transmitted polarized light microscopy. The boundaries of the biphasic region (separated isotropic and anisotropic phases) are parallel, and they have a positive slope, suggesting that phase separation is dictated by hard rod interactions and that conformational disorder decreases the rod axial ratio with increasing temperature. C1 UNIV WASHINGTON,CTR BIOENGN,MOLEC BIOENGN PROGRAM,WD-12,SEATTLE,WA 98195. USA,CTR RES DEV & ENGN,DIV BIOTECHNOL,NATICK,MA 01760. NR 25 TC 14 Z9 15 U1 0 U2 8 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0024-9297 J9 MACROMOLECULES JI Macromolecules PD FEB 14 PY 1994 VL 27 IS 4 BP 953 EP 957 DI 10.1021/ma00082a011 PG 5 WC Polymer Science SC Polymer Science GA MX287 UT WOS:A1994MX28700011 ER PT J AU FUESS, TA HAFEN, ES HARIDAS, P HULSIZER, RI LAINIS, T LEVY, A PLESS, IA SUNG, TW YAMAMOTO, RK WIDGOFF, M RATTI, S ALYEA, ED DIMARCO, R JACQUES, PF KALELKAR, M PLANO, RJ STAMER, P WATTS, TL AF FUESS, TA HAFEN, ES HARIDAS, P HULSIZER, RI LAINIS, T LEVY, A PLESS, IA SUNG, TW YAMAMOTO, RK WIDGOFF, M RATTI, S ALYEA, ED DIMARCO, R JACQUES, PF KALELKAR, M PLANO, RJ STAMER, P WATTS, TL TI DIFFRACTION DISSOCIATION IN PI(+)P INTERACTIONS AT 147 GEV/C SO NUCLEAR PHYSICS B LA English DT Article AB Single diffraction dissociation cross sections of both beam and target particles. have been measured in 147 GeV/c pi+p interactions. The data were recorded by the Fermilab Hybrid 30-inch Bubble Chamber Spectrometer. The diffraction dissociation events are recognized by leading particle signals above background. The pion dissociation cross section is 1895+/-108 mub. The proton dissociation cross section is 1880+/-143 mub. The results are compared to results of a similar study using 147 GeV/c pi-p interactions. These combined results are used to study factorization of the diffraction dissociation cross section. C1 BROWN UNIV,PROVIDENCE,RI 02912. UNIV PAVIA,DIPARTIMENTO FIS NUCL & TEOR,I-27100 PAVIA,ITALY. INDIANA UNIV,BLOOMINGTON,IN 47401. RUTGERS STATE UNIV,NEW BRUNSWICK,NJ 08903. FERMILAB NATL ACCELERATOR LAB,BATAVIA,IL 60510. US MIL ACAD,W POINT,NY 10996. TEL AVIV UNIV,IL-69978 TEL AVIV,ISRAEL. ARETE ASSOCIATES,ARLINGTON,VA 22215. SETON HALL UNIV,S ORANGE,NJ 07079. RP FUESS, TA (reprint author), MIT,CAMBRIDGE,MA 02139, USA. NR 14 TC 1 Z9 1 U1 0 U2 0 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0550-3213 J9 NUCL PHYS B JI Nucl. Phys. B PD FEB 14 PY 1994 VL 414 IS 1-2 BP 3 EP 24 DI 10.1016/0550-3213(94)90418-9 PG 22 WC Physics, Particles & Fields SC Physics GA NA885 UT WOS:A1994NA88500001 ER PT J AU COIMBRA, TLM NASSAR, ES BURATTINI, MN DESOUZA, LTM FERREIRA, IB ROCCO, IM DAROSA, APAT VASCONCELOS, PFC PINHEIRO, FP LEDUC, J RICOHESSE, R GONZALEZ, JP JAHRLING, PB TESH, RB AF COIMBRA, TLM NASSAR, ES BURATTINI, MN DESOUZA, LTM FERREIRA, IB ROCCO, IM DAROSA, APAT VASCONCELOS, PFC PINHEIRO, FP LEDUC, J RICOHESSE, R GONZALEZ, JP JAHRLING, PB TESH, RB TI NEW ARENAVIRUS ISOLATED IN BRAZIL SO LANCET LA English DT Note AB A new arenavirus, called Sabia, was isolated in Brazil from a fatal case of haemorrhagic fever initially thought to be yellow fever. Antigenic and molecular characterisation indicated that Sabia virus is a new member of the Tacaribe complex. A laboratory technician working with the agent was also infected and developed a prolonged, non-fatal influenza-like illness. Sabia virus is yet another arenavirus causing human disease in South America. C1 YALE UNIV,SCH MED,DEPT EPIDEMIOL & PUBL HLTH,YALE ARBOVIRUS RES UNIT,NEW HAVEN,CT 06520. ADOLFO LUTZ INST,VIRUS SERV,SAO PAULO,SP,BRAZIL. PAULISTA MED SCH,INFECT DIS CLIN,SAO PAULO,SP,BRAZIL. EVANDRO CHAGAS INST,DEPT ARBOVIRUS,BELEM,PARA,BRAZIL. PAN AMER HLTH ORG,COMMUNICABLE DIS PROGRAM,WASHINGTON,DC. WHO,MICROBIOL & IMMUNOL SUPPORT SECT,GENEVA,SWITZERLAND. USA,MED RES INST INFECT DIS,FREDERICK,MD. RI Rico-Hesse, Rebeca/C-5294-2011; Burattini, Marcelo/J-9272-2014; OI Rico-Hesse, Rebeca/0000-0001-6216-1000; Burattini, Marcelo/0000-0002-5407-6890; Gonzalez, Jean-Paul/0000-0003-3063-1770 NR 9 TC 46 Z9 47 U1 0 U2 4 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD FEB 12 PY 1994 VL 343 IS 8894 BP 391 EP 392 DI 10.1016/S0140-6736(94)91226-2 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA MW283 UT WOS:A1994MW28300012 ER PT J AU CARR, FE WONG, NCW AF CARR, FE WONG, NCW TI CHARACTERISTICS OF A NEGATIVE THYROID-HORMONE RESPONSE ELEMENT SO JOURNAL OF BIOLOGICAL CHEMISTRY LA English DT Article ID BETA-SUBUNIT GENE; RETINOIC ACID RECEPTORS; AUXILIARY PROTEIN; NUCLEAR RECEPTORS; PROMOTER ACTIVITY; T3 RECEPTOR; X-RECEPTOR; HALF-SITE; TATA BOX; BINDING AB Thyroid hormones may stimulate or repress transcriptional activity depending upon the specific gene. Whereas, a palindromic DNA sequence, TREpal, mediates positive regulation by thyroid hormone, the negative response element (nT(3)RE) remains undefined. Therefore, we have examined the DNA sequences that mediate the inhibitory effects of thyroid hormone on the transcription of the beta-subunit gene of rat thyrotropin (rTSH beta). In rat pituitary tumor cells (GH(3)), transient expression of plasmid constructs containing the putative nT(3)RE of rTSH beta mediated negative regulation by L-triiodothyronine (T-3). Since this nT(3)RE contained sequences which resembled a half-site motif of the consensus T(3)RE and the idealized palindrome (TREpal), we tested a construct containing this half-site motif in the same cells. T-3 decreased the activity of this plasmid. Cotransfection studies in T-3-receptor (T(3)R)-deficient cells indicated that either alpha or beta isoforms of T(3)R were required for the inhibitory effects of the hormone. Both T(3)R isomers bind to DNA sequences containing the nT(3)RE from rTSH beta DNA or the half-site motif of TREpal. In summary, our results show that the repressive properties of T-3 are mediated by a nT(3)RE from rTSH beta. Unexpectedly, this motif resembles a half-site component of TREpal which enhances promoter activity in response to T-3. C1 UNIV CALGARY,DEPT MED & MED BIOCHEM,CALGARY T2N 4N1,AB,CANADA. RP CARR, FE (reprint author), WALTER REED ARMY MED CTR,DEPT CLIN INVEST,RES LABS,KYLE METAB UNIT,6800 GEORGIA AVE,WASHINGTON,DC 20307, USA. NR 33 TC 53 Z9 53 U1 0 U2 0 PU AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 0021-9258 J9 J BIOL CHEM JI J. Biol. Chem. PD FEB 11 PY 1994 VL 269 IS 6 BP 4175 EP 4179 PG 5 WC Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA MW989 UT WOS:A1994MW98900044 PM 8307979 ER PT J AU ROTH, JS KELLEY, JA CHUN, HG WARD, FT AF ROTH, JS KELLEY, JA CHUN, HG WARD, FT TI SIMULTANEOUS MEASUREMENT OF THE CELL-DIFFERENTIATING AGENT HEXAMETHYLENE BISACETAMIDE AND ITS METABOLITES BY GAS-CHROMATOGRAPHY SO JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS LA English DT Article ID MURINE ERYTHROLEUKEMIA-CELLS; PHASE-I TRIAL; MYELODYSPLASTIC SYNDROME; INDUCE DIFFERENTIATION; MYELOID-LEUKEMIA; RETINOIC ACID; NSC-95580; INFUSION; BIOAVAILABILITY; COMBINATIONS AB Hexamethylene bisacetamide (HMBA) is a potent in vitro differentiating agent that has clinical potential as an anticancer drug both as a single agent and as a component of combination therapy. A sensitive and efficient GC method for the isolation, derivatization, and measurement of both HMBA and its two major metabolites in plasma and urine in a single analysis is described. In situ carbamylation of the biological sample with diethylpyrocarbonate forms the urethane derivative of the basic N-acetyl diaminohexane metabolite and allows analyte isolation and concentration by solid-phase extraction. Subsequent formation of the n-butyl ester of 6-acetamidohexanoic acid, the major metabolite, provides a derivatized biological extract that can be rapidly analyzed by temperature-programmed GC. The quantitative extraction and the efficient derivatization steps provide a limit of quantitation of 0.05 mM (10 mug/ml) for all analytes with a precision better than 8% for the range of in vitro activity (0.1-2.0 mM). This method is amenable to automation and is well-suited for the analysis of clinical samples. C1 NCI,DIV CANC TREATMENT,DEV THERAPEUT PROGRAM,MED CHEM LAB,BLDG 37,BETHESDA,MD 20892. NCI,DIV CANC TREATMENT,CANC THERAPY EVALUAT PROGRAM,INVEST DRUG BRANCH,BETHESDA,MD 20892. WALTER REED ARMY MED CTR,DEPT MED,HEMATOL ONCOL SERV,WASHINGTON,DC 20307. NR 35 TC 0 Z9 0 U1 0 U2 5 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0378-4347 J9 J CHROMATOGR B JI J. Chromatogr. B-Biomed. Appl. PD FEB 11 PY 1994 VL 652 IS 2 BP 149 EP 159 DI 10.1016/0378-4347(93)E0395-7 PG 11 WC Biochemical Research Methods; Chemistry, Analytical SC Biochemistry & Molecular Biology; Chemistry GA ND220 UT WOS:A1994ND22000003 PM 8006099 ER PT J AU MEEK, DL PARKER, RG AF MEEK, DL PARKER, RG TI A GRAPH APPROXIMATION HEURISTIC FOR THE VERTEX COVER PROBLEM ON PLANAR GRAPHS SO EUROPEAN JOURNAL OF OPERATIONAL RESEARCH LA English DT Note DE GRAPHS; HEURISTICS; VERTEX COVER ID ALGORITHMS; SET AB The vertex cover problem is hard in general and remains so on planar graphs. On the other hand, it is always solvable on bipartite graphs. In this paper, we introduce a strategy which creates, from an arbitrary planar graph G, a minimum size bipartite homeomorph of G, say G(H). We solve the vertex cover problem on G(H) and convert the solution to a cover on G. Tests on a set of sample graphs suggest that the resulting heuristic performs quite well. C1 GEORGIA INST TECHNOL, SCH IND & SYST ENGN, ATLANTA, GA 30332 USA. US MIL ACAD, DEPT MATH SCI, W POINT, NY 10996 USA. NR 27 TC 2 Z9 2 U1 0 U2 0 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0377-2217 EI 1872-6860 J9 EUR J OPER RES JI Eur. J. Oper. Res. PD FEB 10 PY 1994 VL 72 IS 3 BP 588 EP 597 DI 10.1016/0377-2217(94)90425-1 PG 10 WC Management; Operations Research & Management Science SC Business & Economics; Operations Research & Management Science GA NH587 UT WOS:A1994NH58700011 ER PT J AU SCHODEL, F AF SCHODEL, F TI EMERGING VIRAL MUTANTS IN HEPATITIS-B SO LANCET LA English DT Letter ID ANTIGEN RP SCHODEL, F (reprint author), WALTER REED ARMY INST RES,DEPT BACTERIAL DIS,DIV INFECT DIS & IMMUNOL,WASHINGTON,DC 20307, USA. NR 5 TC 1 Z9 1 U1 0 U2 0 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD FEB 5 PY 1994 VL 343 IS 8893 BP 355 EP 355 DI 10.1016/S0140-6736(94)91192-4 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA MU985 UT WOS:A1994MU98500037 PM 7905163 ER PT J AU LEWIS, MG BELLAH, S MCKINNON, K YALLEYOGUNRO, J ZACK, PM ELKINS, WR DESROSIERS, RC EDDY, GA AF LEWIS, MG BELLAH, S MCKINNON, K YALLEYOGUNRO, J ZACK, PM ELKINS, WR DESROSIERS, RC EDDY, GA TI TITRATION AND CHARACTERIZATION OF 2 RHESUS-DERIVED SIVMAC CHALLENGE STOCKS SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Article ID SIMIAN IMMUNODEFICIENCY VIRUS; CELLULAR-LOCALIZATION; CONFERS PROTECTION; LYMPHOID-TISSUES; MACAQUE MONKEYS; VACCINE; INFECTION; RETROVIRUS; CELLS; AIDS AB Simian immunodeficiency virus infection of macaques is a model for human immunodeficiency virus infection of humans. In vivo-titrated stocks of SIV are essential for the utilization of this model for vaccine development. The elicitation of anti-human cell antibodies by some vaccines prepared in human cells and the related protective effects of the vaccine produced in human cells suggest a need for new macaque-derived SIV stocks. Here we describe the titration and characterization of two stocks of SIVmac that were produced in primary rhesus macaque cells. The first virus is SIVmac251, isolated from tissues of macaque 251, and the second is a molecular clone designated as SIVmac239. A 50% rhesus monkey infectious dose (MID(50)) was titrated for each virus stock by intravenous inoculation. An additional five macaques were inoculated with 10 MID(50) of the SIVmac251 stock and were followed for disease outcome. All five monkeys developed antigenemia by 14 days postchallenge. Two of the five monkeys developed strong anti-SIV humoral immunity, whereas three developed little or no humoral immunity. As has been observed previously, the rapidity of disease progression correlated with the lack of a strong antibody response. The three animals with low humoral immunity died within 7 months of challenge, with antigenemia, cachexia, hypoproteinemia, hypoalbuminemia, weight loss, and intractable diarrhea, while maintaining their circulating CD4 numbers. One animal died at 1.5 years of more typical simian AIDS. C1 WALTER REED ARMY INST RES,DEPT RETROVIROL,WASHINGTON,DC 20307. NIAID,INFECT DIS LAB,ROCKVILLE,MD 20850. NEW ENGLAND REG PRIMATE RES CTR,SOUTHBOROUGH,MA 01772. RP LEWIS, MG (reprint author), HENRY M JACKSON FDN,1500 E GUDE DR,ROCKVILLE,MD 20850, USA. FU NCRR NIH HHS [RR00168]; NIAID NIH HHS [AI26507, AI26463] NR 29 TC 79 Z9 79 U1 0 U2 0 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PD FEB PY 1994 VL 10 IS 2 BP 213 EP 220 DI 10.1089/aid.1994.10.213 PG 8 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA MZ149 UT WOS:A1994MZ14900015 PM 8198874 ER PT J AU EVANS, P HOFMANN, L AF EVANS, P HOFMANN, L TI MALIGNANT EXTERNAL OTITIS - A CASE-REPORT AND REVIEW SO AMERICAN FAMILY PHYSICIAN LA English DT Review AB Malignant external otitis is an unusual but serious and potentially fatal condition that has only recently been described. It is an invasive pseudomonal infection of the external auditory canal and deep periauricular tissues that characteristically involves the bone and adjacent cartilaginous structures, and it may lead to osteomyelitis of the base of the skull. It typically occurs in elderly diabetic patients. Malignant external otitis can cause severe pain, necrosis of the external auditory canal and progressive palsies of the facial and cranial nerves. Treatment consists of debridement of external auditory canal granulation tissue and long-term therapy with an antipseudomonal cephalosporin or an antipseudomonal penicillin plus an aminoglycoside. RP EVANS, P (reprint author), REYNOLDS ARMY COMMUNITY HOSP,FT SILL,OK, USA. NR 0 TC 1 Z9 1 U1 0 U2 0 PU AMER ACAD FAMILY PHYSICIANS PI KANSAS CITY PA 8880 WARD PARKWAY, KANSAS CITY, MO 64114-2797 SN 0002-838X J9 AM FAM PHYSICIAN JI Am. Fam. Physician PD FEB 1 PY 1994 VL 49 IS 2 BP 427 EP 431 PG 5 WC Primary Health Care; Medicine, General & Internal SC General & Internal Medicine GA MV895 UT WOS:A1994MV89500016 PM 8304263 ER PT J AU SOLOMON, BL SCHAAF, M SMALLRIDGE, RC AF SOLOMON, BL SCHAAF, M SMALLRIDGE, RC TI PSYCHOLOGIC SYMPTOMS BEFORE AND AFTER PARATHYROID SURGERY SO AMERICAN JOURNAL OF MEDICINE LA English DT Article ID PRIMARY HYPERPARATHYROIDISM; MANIFESTATIONS AB PURPOSE: To identify in an outpatient setting the type and number of psychologic symptoms of patients with primary hyperparathyroidism before and after surgery. PATIENTS AND METHODS: A convenience sample of 18 patients with primary hyperparathyroidism and a comparison sample of 20 patients with benign thyroid disease were scheduled by their primary care physician to have surgery. Assessments of psychologic symptoms, using the Symptom Checklist-90-Revised, and measurements of serum total calcium, ionized calcium, parathyroid hormone, albumin, alkaline phosphatase, urea nitrogen, creatinine, protein, and phosphate were obtained preoperatively and at 1, 3, and 6 months postoperatively. RESULTS: The hyperparathyroid group had significantly higher (p <0.01) levels of total and ionized serum calcium and parathyroid hormone preoperatively, with biochemical normalization 1 month postoperatively. These patients showed multidimensional psychologic symptom distress preoperatively in the areas of obsession-compulsion, interpersonal sensitivity, depression, anxiety, hostility, and psychoticism; they also had a greater number and intensity of distressful symptoms. Paranoid ideation was significantly higher in the hyperparathyroid group than in the comparison group, but it did not quite reach the clinical range.The greatest improvement in symptoms occurred by 1 month after surgery, with the hyperparathyroid group approaching the normative mean. There were no group differences before or after surgery for the areas of somatization and phobic anxiety. CONCLUSIONS: The Symptom Checklist-90-Revised is a simple, quick, and cost-effective way to quantitatively assess the psychologic symptoms of patients with primary hyperparathyroidism. We found that psychologic symptom distress is multidimensional, that symptoms had profoundly improved by 1 month after parathyroidectomy, and that somatization and anxiety did not differ between our groups. C1 WALTER REED ARMY MED CTR,DEPT MED,ENDOCRINE METAB SERV,WASHINGTON,DC 20307. WALTER REED ARMY INST RES,DIV MED,WASHINGTON,DC. RP SOLOMON, BL (reprint author), WALTER REED ARMY MED CTR,DEPT CLIN INVEST,ENDOCRINE METAB SERV 7D,WASHINGTON,DC 20307, USA. NR 19 TC 84 Z9 85 U1 0 U2 1 PU EXCERPTA MEDICA INC PI NEW YORK PA 245 WEST 17TH STREET, NEW YORK, NY 10011 SN 0002-9343 J9 AM J MED JI Am. J. Med. PD FEB PY 1994 VL 96 IS 2 BP 101 EP 106 DI 10.1016/0002-9343(94)90128-7 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA MY471 UT WOS:A1994MY47100004 PM 8109593 ER PT J AU MCCARTHY, MF HONDRUM, SO AF MCCARTHY, MF HONDRUM, SO TI MECHANICAL AND BOND STRENGTH PROPERTIES OF LIGHT-CURED AND CHEMICALLY CURED GLASS-IONOMER CEMENTS SO AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS LA English DT Article AB The purpose of this study was to evaluate the mechanical and bond strength properties of a commercially available light-cured glass ionomer cement and of a chemically cured glass ionomer cement. Sixty recently extracted human molars were randomly divided into six equal groups, and the bond strengths of the two cement types were evaluated at 1 hour, 24 hours, and 7 days. Stainless steel lingual buttons were bonded to prepared enamel surfaces, and the samples were placed in a water bath at 37-degrees-C until testing. The shear bond strength of each sample was determined with a universal testing instrument. The mechanical strength properties of the two cements were then evaluated. The transverse flexural strength, compressive strength, rigidity, and diametral tensile strength were tested for each cement at 1 hour, 24 hours, and 7 days. The results of the mechanical property strength tests were then compared with the results of the bond strength tests. The results from the study conclude: (1) The light-cured cement achieves maximum tensile strength faster than the chemically cured material; (2) the bond strengths of both chemically cured and light-cured glass ionomer cements increase with time; (3) the bond strength of light-cured cement was greater than the proposed minimum level for clinical success at all test times whereas the bond strength of the chemically cured material did not reach minimum levels until after 24 hours; (4) the bond failures of the glass ionomer cements are primarily cohesive; and, (5) there is a high correlation between the diametral tensile strength and the bond strength for glass ionomer cements at 1 hour and 24 hours (r = 0.98). C1 USA,DENT CORPS,ORTHODONT RESIDENCY PROGRAM,FT GEORGE G MEADE,MD. USA,INST DENT RES,FT GEORGE G MEADE,MD. NR 19 TC 30 Z9 34 U1 0 U2 2 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0889-5406 J9 AM J ORTHOD DENTOFAC JI Am. J. Orthod. Dentofac. Orthop. PD FEB PY 1994 VL 105 IS 2 BP 135 EP 141 DI 10.1016/S0889-5406(94)70109-1 PG 7 WC Dentistry, Oral Surgery & Medicine SC Dentistry, Oral Surgery & Medicine GA MX582 UT WOS:A1994MX58200010 PM 8311035 ER PT J AU MODESTO, VL HARKINS, B CALTON, WC MARTINDALE, RG AF MODESTO, VL HARKINS, B CALTON, WC MARTINDALE, RG TI LAPAROSCOPIC GASTROSTOMY USING 4-POINT FIXATION SO AMERICAN JOURNAL OF SURGERY LA English DT Article ID PERCUTANEOUS ENDOSCOPIC GASTROSTOMY AB Percutaneous endoscopic gastrostomy (PEG) has become an effective alternative to surgical gastrostomy in patients who require enteral access or gastric decompression. Technical considerations, however, limit the application of PEG in selected patients and those who have contraindications to PEG. Laparoscopic gastrostomy tube placement has been introduced as an alternative to PEG. A technique for laparoscopic gastrostomy tube placement that emphasizes four-point fixation of the anterior gastric wall is presented. C1 USA MED CORPS,DWIGHT DAVID EISENHOWER ARMY MED CTR,FT GORDON,GA. NR 7 TC 17 Z9 17 U1 0 U2 0 PU CAHNERS PUBL CO PI NEW YORK PA 249 WEST 17 STREET, NEW YORK, NY 10011 SN 0002-9610 J9 AM J SURG JI Am. J. Surg. PD FEB PY 1994 VL 167 IS 2 BP 273 EP 276 DI 10.1016/0002-9610(94)90091-4 PG 4 WC Surgery SC Surgery GA MY223 UT WOS:A1994MY22300014 PM 8135319 ER PT J AU WATT, G LOESUTTIVIBOON, L JONGSAKUL, K SHANKS, GD OHRT, CK KARNASUTA, C SCHUSTER, B FLECKENSTEIN, L AF WATT, G LOESUTTIVIBOON, L JONGSAKUL, K SHANKS, GD OHRT, CK KARNASUTA, C SCHUSTER, B FLECKENSTEIN, L TI EFFICACY AND TOLERANCE OF EXTENDED-DOSE HALOFANTRINE FOR DRUG-RESISTANT FALCIPARUM-MALARIA IN THAILAND SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID PLASMODIUM-FALCIPARUM; PHARMACOKINETICS; TETRACYCLINE; QUININE AB New treatments for malaria are urgently needed in areas such as Thailand where highly drug-resistant strains of Plasmodium falciparum are prevalent. Mefloquine is rapidly losing efficacy and conventional doses of halofantrine are ineffective. We therefore used pharmacokinetic simulation to design an extended-dose halofantrine regimen and tested it in 26 soldiers stationed along the Thai-Cambodian border. Halofantrine was given after meals as three doses of 500 mg each at 4-hr intervals on the first day, followed by 500 mg a day for six days (total dose 4.5 g). Twenty-six soldiers treated with quinine-tetracycline for seven days (Q(7)T(7)) served as controls. There were no significant differences in efficacy between halofantrine and Q(7)T(7) (P > 0.1) as assessed by cure rate (92% versus 85%), mean parasite clearance time (82 hr versus 81 hr), or mean fever clearance time (93 hr versus 99 hr). Halofantrine was better tolerated than Q(7)T(7). The side effects score was lower (2 versus 11; P < 0.001), there were less days on which side effects occurred (2.0 days versus 5.5 days; P < 0.001), and fewer patients had adverse effects on every treatment day (4% versus 42%; P < 0.01). High-dose halofantrine is as effective and better tolerated than quinine-tetracycline for multidrug-resistant falciparum malaria. C1 SURASINGHANAT ROYAL THAI ARMY HOSP,ARANYAPRATHET,THAILAND. WALTER REED ARMY INST RES,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307. UNIV IOWA,COLL PHARM,IOWA CITY,IA 52242. RP WATT, G (reprint author), ARMED FORCES RES INST MED SCI,DEPT MED,APO AP 96546,BANGKOK,THAILAND. RI Shanks, George Dennis/F-4056-2014 OI Fleckenstein, Lawrence/0000-0001-5320-4531; Shanks, George Dennis/0000-0001-5763-8660 NR 12 TC 11 Z9 11 U1 0 U2 0 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD FEB PY 1994 VL 50 IS 2 BP 187 EP 192 PG 6 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA MZ147 UT WOS:A1994MZ14700010 PM 8116811 ER PT J AU BASCO, LK ANDERSEN, SL MILHOUS, WK LEBRAS, J VENNERSTROM, JL AF BASCO, LK ANDERSEN, SL MILHOUS, WK LEBRAS, J VENNERSTROM, JL TI IN-VITRO ACTIVITY OF BISQUINOLINE WR268,668 AGAINST AFRICAN CLONES AND ISOLATES OF PLASMODIUM-FALCIPARUM SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID PLASMODIUM-FALCIPARUM; CHLOROQUINE RESISTANCE; INVITRO; DESIPRAMINE; REVERSAL; MALARIA AB The in vitro activity of a new bisquinoline, WR268,668, was determined against chloroquine-susceptible and chloroquine-resistant African clones and isolates of Plasmodium falciparum using an isotopic semimicro drug susceptibility assay. The chloroquine-resistant clone (mean 50% inhibitory concentration [IC50] = 61.2 nM) was 11 times less susceptible to WR268,668 than the chloroquine-susceptible clone (IC50 = 5.75 nM). A similar result was obtained with fresh clinical isolates, with the chloroquine-susceptible isolates OC,, = 5.36 nM, n = If) being significantly (P < 0.05) more susceptible to WR268,668 than the chloroquine-resistant isolates (IC50 = 16.1 nM, n = 18). The compound WR268,668 exhibited a high activity against some moderately chloroquine-resistant isolates. There was a significant positive correlation between the in vitro responses to chloroquine and WR268,668 (r = 0.904, P < 0.05). Combinations of WR268,668 and desipramine, a chloroquine efflux inhibitor, showed that resistance to WR268,668 can be reversed against the chloroquine-resistant clone and that desipramine has no effect on the activity of WR268,668 against the chloroquine-susceptible clone. The results of the study indicate the presence of cross-resistance between chloroquine and WR268,668, and suggest that the basis of resistance to WR268,668 may be similar to that of other 4-aminoquinolines. C1 WALTER REED ARMY INST RES,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307. UNIV NEBRASKA,MED CTR,COLL PHARM,OMAHA,NE 68198. RP BASCO, LK (reprint author), HOP BICHAT CLAUDE BERNARD,CTR NATL REFERENCE CHIMIOSENSIBIL PALUDISME,INST MED & EPIDEMIOL TROP,F-75877 PARIS 18,FRANCE. NR 17 TC 18 Z9 18 U1 0 U2 1 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD FEB PY 1994 VL 50 IS 2 BP 200 EP 205 PG 6 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA MZ147 UT WOS:A1994MZ14700012 PM 8116813 ER PT J AU BOYLE, T LANCASTER, V HUNT, R GEMSKI, P JETT, M AF BOYLE, T LANCASTER, V HUNT, R GEMSKI, P JETT, M TI METHOD FOR SIMULTANEOUS ISOLATION AND QUANTITATION OF PLATELET-ACTIVATING-FACTOR AND MULTIPLE ARACHIDONATE METABOLITES FROM SMALL SAMPLES - ANALYSIS OF EFFECTS OF STAPHYLOCOCCUS-AUREUS ENTEROTOXIN-B IN MICE SO ANALYTICAL BIOCHEMISTRY LA English DT Article ID PERFORMANCE LIQUID-CHROMATOGRAPHY; RESPIRATORY-DISTRESS SYNDROME; FATTY-ACIDS; LEUKOTRIENES; LIPOXYGENASE; SEPARATION; PROSTAGLANDINS; PURIFICATION; PRODUCTS; CYCLOOXYGENASE C1 WALTER REED ARMY INST RES,DEPT MOLEC PATHOL,WASHINGTON,DC 20307. WALTER REED ARMY INST RES,DEPT COMPARAT PATHOL,WASHINGTON,DC 20307. GEORGETOWN UNIV,DEPT CHEM,WASHINGTON,DC 20057. NR 33 TC 14 Z9 15 U1 0 U2 4 PU ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 SN 0003-2697 J9 ANAL BIOCHEM JI Anal. Biochem. PD FEB 1 PY 1994 VL 216 IS 2 BP 373 EP 382 DI 10.1006/abio.1994.1055 PG 10 WC Biochemical Research Methods; Biochemistry & Molecular Biology; Chemistry, Analytical SC Biochemistry & Molecular Biology; Chemistry GA MU712 UT WOS:A1994MU71200018 PM 8179192 ER PT J AU MONGAN, PD PETERSON, RE WILLIAMS, D AF MONGAN, PD PETERSON, RE WILLIAMS, D TI SPINAL EVOKED-POTENTIALS ARE PREDICTIVE OF NEUROLOGIC FUNCTION IN A PORCINE MODEL OF AORTIC OCCLUSION SO ANESTHESIA AND ANALGESIA LA English DT Article ID CEREBROSPINAL-FLUID DRAINAGE; CORD BLOOD-FLOW; TRANSCRANIAL ELECTRICAL-STIMULATION; THORACIC AORTA; NITROUS-OXIDE; MOTOR TRACTS; ISCHEMIA; SURGERY; PARAPLEGIA; OPERATIONS AB The limitations of somatosensory evoked potentials during aortic occlusion stimulated us to evaluate the sensitivity and specificity of spinal (T10 and L4) evoked potentials (SpEPs) in predicting neurologic function after aortic occlusion. Thirty-six swine were assigned randomly to three equal groups (Group 1, control; Group 2, cerebrospinal fluid (CSF) drainage; Group 3, CSF drainage with 20-mg intrathecal papaverine). After induction of anesthesia and initiation of physiologic monitoring, a left-sided thoracotomy was performed to provide access to the descending aorta. SpEPs were generated by stimulating the thoracic spinal cord and recording the conducted response at the T10 and L4 level. After baseline measurements were recorded, the descending aorta was occluded 1 cm distal to the left subclavian artery. SpEPs were recorded every 2.5 min and physiologic variables every 5 min. The aorta was unclamped 10, 15, or 20 min after loss of the L4 SpEP. If the L4 SpEP was not lost, the aortic occlusion interval was terminated at 90 min. Attenuation of the SpEPs occurred earlier at the L4 level. Group 1 experienced the earliest loss of the L4 SpEP (18.3 +/- 7.8 min, P < 0.005). Loss of the L4 SpEP in Group 2 (49.3 +/- 27.8 min) was earlier than in Group 3 (73.7 +/- 26.1 min, P < 0.05). Early postoperative motor function (modified Tarlov scale) correlated with time from loss of the L4 SpEP until reperfusion of the distal aorta (r = 0.93). The sensitivity, specificity, and accuracy of the L4 SpEP in predicting neurologic dysfunction was 92.8% (13 abnormal/14 predicted), 90.9% (20/22), and 91.7% (33/36). SpEPs provide an assessment of the response to protective measures and are accurate predictors of early postoperative motor function. Further evaluation of SpEPs may discern similar results in clinical practice. C1 BROOKE ARMY MED CTR, DEPT CLIN INVEST, FT SAM HOUSTON, TX USA. RP MONGAN, PD (reprint author), BROOKE ARMY MED CTR, DEPT SURG, ANESTHESIA & OPERAT SERV, FT SAM HOUSTON, TX 78234 USA. NR 44 TC 11 Z9 11 U1 0 U2 0 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0003-2999 J9 ANESTH ANALG JI Anesth. Analg. PD FEB PY 1994 VL 78 IS 2 BP 257 EP 266 DI 10.1213/00000539-199402000-00011 PG 10 WC Anesthesiology SC Anesthesiology GA NA399 UT WOS:A1994NA39900011 PM 8311277 ER PT J AU DANIELS, DJ PRICE, C KIM, KC AF DANIELS, DJ PRICE, C KIM, KC TI RELATIONSHIP OF PREHYDRATION AND EPHEDRINE REQUIREMENT IN THE PARTURIENT PRESENTING FOR CESAREAN-SECTION SO ANESTHESIA AND ANALGESIA LA English DT Meeting Abstract C1 TRIPLER ARMY MED CTR,ANESTHESIA & OPERAT SERV,TRIPLER,HI 96859. NR 4 TC 0 Z9 0 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0003-2999 J9 ANESTH ANALG JI Anesth. Analg. PD FEB PY 1994 VL 78 IS 2 SU S BP U54 EP U54 PG 1 WC Anesthesiology SC Anesthesiology GA NA406 UT WOS:A1994NA40600080 ER PT J AU DANIELS, DJ PRICE, C KIM, KC AF DANIELS, DJ PRICE, C KIM, KC TI VARIABLES WHICH MAY INFLUENCE SPREAD OF SUBARACHNOID BLOCK IN PARTURIENTS PRESENTING FOR CESAREAN SO ANESTHESIA AND ANALGESIA LA English DT Meeting Abstract C1 TRIPLER ARMY MED CTR,ANESTHESIA & OPERAT SERV,TRIPLER,HI 96859. NR 3 TC 0 Z9 0 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0003-2999 J9 ANESTH ANALG JI Anesth. Analg. PD FEB PY 1994 VL 78 IS 2 SU S BP U54 EP U54 PG 1 WC Anesthesiology SC Anesthesiology GA NA406 UT WOS:A1994NA40600081 ER PT J AU MONGAN, PD HOSKING, MP AF MONGAN, PD HOSKING, MP TI DESMOPRESSIN DECREASES BLOOD-LOSS AND TRANSFUSION THERAPY AFTER HIGH-RISK CPB PROCEDURES SO ANESTHESIA AND ANALGESIA LA English DT Meeting Abstract C1 BROOKE ARMY MED CTR,DEPT ANESTHESIA,FT SAM HOUSTON,TX 78234. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0003-2999 J9 ANESTH ANALG JI Anesth. Analg. PD FEB PY 1994 VL 78 IS 2 SU S BP U159 EP U159 PG 1 WC Anesthesiology SC Anesthesiology GA NA406 UT WOS:A1994NA40600290 ER PT J AU POLO, KB JABBARI, B AF POLO, KB JABBARI, B TI BOTULINUM TOXIN-A IMPROVES THE RIGIDITY OF PROGRESSIVE SUPRANUCLEAR PALSY SO ANNALS OF NEUROLOGY LA English DT Note ID HEMIFACIAL SPASM; SPASTICITY AB Botulinum toxin-A (botox) can improve spasticity and decrease painful spasms in the affected limbs of patients with multiple sclerosis. We report significant improvement of muscle rigidity in the upper limbs after focal administration of botulinum toxin A to 2 patients with progressive supranuclear palsy. C1 WALTER REED ARMY MED CTR,NEUROL SERV,WASHINGTON,DC 20307. UNIFORMED SERV UNIV HLTH SCI,DEPT NEUROL,BETHESDA,MD 20814. NR 11 TC 20 Z9 20 U1 0 U2 0 PU LITTLE BROWN CO PI BOSTON PA 34 BEACON STREET, BOSTON, MA 02108-1493 SN 0364-5134 J9 ANN NEUROL JI Ann. Neurol. PD FEB PY 1994 VL 35 IS 2 BP 237 EP 239 DI 10.1002/ana.410350218 PG 3 WC Clinical Neurology; Neurosciences SC Neurosciences & Neurology GA MW506 UT WOS:A1994MW50600017 PM 8109906 ER PT J AU SFIKAKIS, PP TESAR, J THEOCHARIS, S KLIPPLE, GL TSOKOS, GC AF SFIKAKIS, PP TESAR, J THEOCHARIS, S KLIPPLE, GL TSOKOS, GC TI INCREASED FREQUENCY OF IN-VIVO HPRT GENE-MUTATED T-CELLS IN THE PERIPHERAL-BLOOD OF PATIENTS WITH SYSTEMIC-SCLEROSIS SO ANNALS OF THE RHEUMATIC DISEASES LA English DT Article ID LYMPHOCYTES-T; MUTANT FREQUENCY; CLONING ASSAY; SCLERODERMA; INTERLEUKIN-2; RECEPTOR; PATHOGENESIS; MUTATIONS; COLLAGEN; QUANTIFY AB Objectives-Activated T lymphocytes are involved in the pathogenesis of scleroderma (systemic sclerosis, SSc); such cells rapidly divide in vivo and are thus theoretically subject to random mutation more frequently than resting cells. To study whether SSc is associated with rapidly expanding T cell clones the frequency was determined of in vivo mutated T cells (MF) at the hypoxanthine guanine phosphoribosyl transferase (hprt) gene in the peripheral blood from patients with SSc. Specific clinical or serological associations were also investigated. Methods-Peripheral blood lymphocytes from 16 healthy individuals and 20 patients with SSc were cultured using an hprt clonal assay; mutated and wild T cell clones were established to assess individual values of T cell MF. T cell clones were further expanded in vitro and their phenotype was determined by standard immunofluorescence technique. Enzyme-linked immunosorbent assays were used for simultaneous measurements of plasma levels of soluble Interleukin-2 receptors (s-IL-2R) and Intercellular adhesion molecule-1 (s-ICAM-1). Results-Mean (SD) value of T cell MF in patients with SSc was 2.5-fold higher than the normal mean (SD) value [10.6 (6.6) x 10(-6) v [4.4 (2.8) x 10(-6), p = 0.0007]. Eleven of 20 patients with SSc (55%) had T cell MF values greater than two SD above the normal mean value. The majority (84%) of mutated T cells had a helper/inducer, memory phenotype while 12% were cytotoxic/suppressor T cells. There was no association between T cell MF and the extent of skin involvement or the duration of Raynaud's phenomenon. High individual T cell IMF values were not related to a possible concurrent immune overactivity as assessed by plasma levels of s-IL-2R and s-ICAM-1. Patients with long standing skin disease, however, had almost double GC T cell MF values than T patients with early skin disease [(13.6 (7.4)) x 10(-6) v (7.5 (4.3)) x 10(-6), p = 0.03], suggesting that increased T cell MF in SSc may reflect an ongoing process of chronic in vivo T cell proliferation and/or prolonged survival. Conclusion-Increased in vivo T cell mutation in patients with SSc suggests that excessive division and/or survival of T cell clones contribute to the pathology in SSc; this approach can be used in further investigations to identify the stimulus that is triggering T cell activation in this disease. C1 UNIFORMED SERV UNIV HLTH SCI,DEPT MED,BETHESDA,MD 20814. WALTER REED ARMY MED CTR,DEPT CLIN INVEST,RHEUMATOL & CLIN IMMUNOL SERV,WASHINGTON,DC 20307. NR 36 TC 15 Z9 15 U1 0 U2 0 PU BRITISH MED JOURNAL PUBL GROUP PI LONDON PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON, ENGLAND WC1H 9JR SN 0003-4967 J9 ANN RHEUM DIS JI Ann. Rheum. Dis. PD FEB PY 1994 VL 53 IS 2 BP 122 EP 127 DI 10.1136/ard.53.2.122 PG 6 WC Rheumatology SC Rheumatology GA MW087 UT WOS:A1994MW08700008 PM 8129457 ER PT J AU BELL, R MEISELMAN, HL PIERSON, BJ REEVE, WG AF BELL, R MEISELMAN, HL PIERSON, BJ REEVE, WG TI EFFECTS OF ADDING AN ITALIAN THEME TO A RESTAURANT ON THE PERCEIVED ETHNICITY, ACCEPTABILITY, AND SELECTION OF FOODS SO APPETITE LA English DT Article ID VARIETY SEEKING; BEHAVIOR C1 BOURNEMOUTH UNIV,DEPT FOOD & HOSP MANAGEMENT,BOURNEMOUTH,ENGLAND. RP BELL, R (reprint author), USA,NATICK RES DEV & ENGN CTR,KANSAS ST,NATICK,MA 01760, USA. NR 26 TC 53 Z9 54 U1 2 U2 9 PU ACADEMIC PRESS LTD PI LONDON PA 24-28 OVAL RD, LONDON, ENGLAND NW1 7DX SN 0195-6663 J9 APPETITE JI Appetite PD FEB PY 1994 VL 22 IS 1 BP 11 EP 24 DI 10.1006/appe.1994.1002 PG 14 WC Behavioral Sciences; Nutrition & Dietetics SC Behavioral Sciences; Nutrition & Dietetics GA MW824 UT WOS:A1994MW82400002 PM 8172487 ER PT J AU BISWAS, R STRAWN, RC AF BISWAS, R STRAWN, RC TI A NEW PROCEDURE FOR DYNAMIC ADAPTION OF 3-DIMENSIONAL UNSTRUCTURED GRIDS SO APPLIED NUMERICAL MATHEMATICS LA English DT Article ID MESHES; SCHEME AB A new procedure is presented for the simultaneous coarsening and refinement of three-dimensional unstructured tetrahedral meshes. This algorithm allows for localized grid adaption that is used to capture aerodynamic flow features such as vortices and shock waves in helicopter flowfield simulations. The mesh-adaption algorithm is implemented in the C programming language and uses a data structure consisting of a series of dynamically-allocated linked lists. These lists allow the mesh connectivity to be rapidly reconstructed when individual mesh points are added and/or deleted. The algorithm allows the mesh to change in an anisotropic manner in order to efficiently resolve directional flow features. The procedure has been successfully implemented on a single processor of a Cray Y-MP computer. Two sample cases are presented involving three-dimensional transonic flow. Computed results show good agreement with conventional structured-grid solutions for the Euler equations. C1 NASA,AMES RES CTR,USA,MOFFETT FIELD,CA 94035. RP BISWAS, R (reprint author), NASA,AMES RES CTR,RIACS,MAIL STOP T27A-1,MOFFETT FIELD,CA 94035, USA. NR 13 TC 27 Z9 27 U1 0 U2 0 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0168-9274 J9 APPL NUMER MATH JI Appl. Numer. Math. PD FEB PY 1994 VL 13 IS 6 BP 437 EP 452 DI 10.1016/0168-9274(94)90007-8 PG 16 WC Mathematics, Applied SC Mathematics GA NC694 UT WOS:A1994NC69400001 ER PT J AU SAU, P MCMARLIN, SL SPERLING, LC KATZ, R AF SAU, P MCMARLIN, SL SPERLING, LC KATZ, R TI BOWENS-DISEASE OF THE NAIL BED AND PERIUNGUAL AREA - A CLINICOPATHOLOGICAL ANALYSIS OF 7 CASES SO ARCHIVES OF DERMATOLOGY LA English DT Article ID HUMAN PAPILLOMAVIRUS-16 DNA; SQUAMOUS-CELL CARCINOMA; PAPULOSIS; DYSPLASIA AB Background: This article describes the clinical and histologic features of seven cases of Bowen's disease (BD) of the nail bed, evaluates the role of human papillomavirus in the bowenoid change, and discusses optimal therapy. Observation: The patients presented with the clinical features of verruca vulgaris (n=3), nail dystrophy and onycholysis (n=2), paronychia (n=1), and acral melanoma (n=1). Histologically, the lesions demonstrated acanthosis, hyperkeratosis, and anaplasia, involving the full thickness of the epithelium. In four cases, human papillomavirus type 16 was demonstrated by in situ hybridization. Six lesions were treated by Mohs micrographic surgery, and one case was treated with topical 5% fluorouracil. In two cases, lesions recurred 1 and 2 years following surgery. In the case treated with topical 5% fluorouracil, residual BD was found 6 weeks after therapy. This case was then treated by Mohs surgery. Conclusions: Bowen's disease of the nail bed and periungual area may present clinically as various inflammatory and neoplastic conditions. An important clinical finding in differentiating BD of the nail bed from verruca is the presence of scaling and onycholysis that are out of proportion to the verrucous changes. Human papillomavirus type 16 may be etiologically related to BD of the nail bed and periungual area. Mohs micrographic surgery is recommended for adequate excision and maximal preservation of normal tissue and function. C1 WALTER REED ARMY MED CTR,DEPT DERMATOL,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,DEPT PATHOL,WASHINGTON,DC 20307. NR 31 TC 75 Z9 75 U1 0 U2 2 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0003-987X J9 ARCH DERMATOL JI Arch. Dermatol. PD FEB PY 1994 VL 130 IS 2 BP 204 EP 209 DI 10.1001/archderm.130.2.204 PG 6 WC Dermatology SC Dermatology GA MV881 UT WOS:A1994MV88100009 PM 8304759 ER PT J AU SMITH, KJ YEAGER, J SKELTON, HG ANGRITT, P AF SMITH, KJ YEAGER, J SKELTON, HG ANGRITT, P TI DIFFUSE PETECHIAL PUSTULAR LESIONS IN A NEWBORN - DISSEMINATED LISTERIA-MONOCYTOGENES SO ARCHIVES OF DERMATOLOGY LA English DT Note ID INFECTION C1 NATL NAVAL MED CTR, WASHINGTON, DC USA. ARMED FORCES INST PATHOL, WASHINGTON, DC USA. AIDS REGISTRY, WASHINGTON, DC USA. RP SMITH, KJ (reprint author), WALTER REED ARMY INST RES, WASHINGTON, DC 20307 USA. NR 8 TC 1 Z9 1 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0003-987X J9 ARCH DERMATOL JI Arch. Dermatol. PD FEB PY 1994 VL 130 IS 2 BP 245 EP + DI 10.1001/archderm.130.2.245 PG 0 WC Dermatology SC Dermatology GA MV881 UT WOS:A1994MV88100018 PM 8304768 ER PT J AU BEARD, JS SPERLING, L TUNNESSEN, WW AF BEARD, JS SPERLING, L TUNNESSEN, WW TI PICTURE OF THE MONTH - CONGENITAL CARTILAGINOUS RESTS OF THE NECK (WATTLES) SO ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE LA English DT Note C1 WALTER REED ARMY MED CTR,DERMATOL SERV,WASHINGTON,DC 20307. RI Sperling, Linda/C-9734-2014 NR 5 TC 1 Z9 1 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 1072-4710 J9 ARCH PEDIAT ADOL MED JI Arch. Pediatr. Adolesc. Med. PD FEB PY 1994 VL 148 IS 2 BP 211 EP 212 PG 2 WC Pediatrics SC Pediatrics GA ND430 UT WOS:A1994ND43000018 PM 8118545 ER PT J AU ROBERTSON, FM OFFNER, PJ CICERI, DP BECKER, WK PRUITT, BA BILLIAR, TR AF ROBERTSON, FM OFFNER, PJ CICERI, DP BECKER, WK PRUITT, BA BILLIAR, TR TI DETRIMENTAL HEMODYNAMIC-EFFECTS OF NITRIC-OXIDE SYNTHASE INHIBITION IN SEPTIC SHOCK SO ARCHIVES OF SURGERY LA English DT Article; Proceedings Paper CT 13th Annual Meeting of the Surgical-Infection-Society CY APR 29, 1993 CL BALTIMORE, MD SP SURG INFECT SOC ID HYPOXIC PULMONARY VASOCONSTRICTION; ORGAN BLOOD-FLOW; L-ARGININE; RELAXING FACTOR; ENDOTHELIAL-CELLS; ENDOTOXIC-SHOCK; PIGS; CIRCULATION; RESPONSES; IBUPROFEN AB Objective: To investigate the physiologic effects of nitric oxide synthase inhibition with N-nitro-L-arginine methyl ester in an acute resuscitated model of porcine septic shock. Design: Randomized control trial. Setting: Animal research facility. Study Subjects: Domestic Yorkshire swine. Interventions: Twenty-four animals were randomly divided into one of four treatment groups as follows: normal saline resuscitation (NSR) (control group); NSR plus 200 mu g/kg of lipopolysaccharide (LPS) at 1 hour after baseline (LPS group); NSR, LPS, and a continuous infusion of 50 mu g/kg per minute of N-nitro-L-arginine methyl ester (NAME) at 1 hour after baseline (LPS/NAME group); and NSR and NAME (NAME group). All animals received NSR at 1 mL/kg per minute starting at baseline. Main Outcome Measures: Mean arterial pressure (MAP), systemic vascular resistance index (SVRI), mean pulmonary arterial pressure (MPAP), and pulmonary vascular resistance index (PVRI) were measured at baseline and hourly for 4 hours. Values at baseline and 3 hours are given below as mean (+/-SE). Results: All variables remained unchanged in the control group. The administration of LPS produced a systemic hyperdynamic response characterized by a decrease in MAP and SVRI from 66.0+/-3.9 to 55+/-2.8 mm Hg (P<.05) and from 422.0+/-22.0 to 272.0+/-29.0 mm Hg.min.kg/L (P<.05), respectively. The administration of LPS produced an increase in MPAP and PVRI from 16.3+/-0.8 to 30.0+/-1.3 mm Hg (P<.05) and from 37.0+/-5.3 to 119.0+/-13.0 mm Hg.min.kg/L (P<.05), respectively. In the LPS/NAME group, NAME infusion normalized MAP and increased SVRI from 506.0+/-40.0 to 642.0+/-72.0 mm Hg.min.kg/L (P<.05). Infusion of NAME potentiated LPS-induced pulmonary hypertension, increasing MPAP and PVRI from 16.8+/-0.6 to 36.0+/-2.8 mm Hg (P<.05) and from 59.0+/-3.5 to 319.0+/-64.0 mm Hg.min.kg/L (P<.05), respectively. Infusion of NAME alone increased MAP from 74.0+/-1.3 to 100.0+/-4.1 mm Hg (P<.05) and had no significant effect on MPAP and PVRI. Conclusions: The potentiation of LPS-induced pulmonary hypertension following NAME infusion suggests that inhibition of nitric oxide synthase may have a limited role in the treatment of septic shock. C1 BROOKE ARMY MED CTR,DEPT SURG,CRIT CARE SERV,FT SAM HOUSTON,TX 78234. USA,INST SURG RES,FT SAM HOUSTON,TX 78234. NR 38 TC 99 Z9 99 U1 0 U2 1 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0004-0010 J9 ARCH SURG-CHICAGO JI Arch. Surg. PD FEB PY 1994 VL 129 IS 2 BP 149 EP 156 PG 8 WC Surgery SC Surgery GA MV880 UT WOS:A1994MV88000005 PM 7508219 ER PT J AU RABIN, J AF RABIN, J TI FLICKER DETECTION THROUGH NIGHT-VISION GOGGLES SO AVIATION SPACE AND ENVIRONMENTAL MEDICINE LA English DT Article AB Visual performance through night vision goggles (NVG's) is commonly assessed with letter charts or other static displays. Few attempts have been made to evaluate dynamic aspects of vision through NVG's. Such information may be used to better predict human performance and guide the development of improved devices. In this study, contrast thresholds for detection of flickering targets were measured through NVG's across a range of ambient conditions. A comparison of measurements with and without NVG's indicated that flicker detection is limited by the contrast and luminance of the NVG display. The contrast limitation is largely independent of stimulus flicker frequency. Increasing the transfer of static contrast and/or luminance through NVG's will also improve dynamic visual performance. RP RABIN, J (reprint author), USA,AEROMED RES LAB,SENSORY RES DIV,POB 620577,FT RUCKER,AL 36362, USA. NR 8 TC 1 Z9 1 U1 0 U2 0 PU AEROSPACE MEDICAL ASSOC PI ALEXANDRIA PA 320 S HENRY ST, ALEXANDRIA, VA 22314-3579 SN 0095-6562 J9 AVIAT SPACE ENVIR MD JI Aviat. Space Environ. Med. PD FEB PY 1994 VL 65 IS 2 BP 106 EP 109 PG 4 WC Public, Environmental & Occupational Health; Medicine, General & Internal; Sport Sciences SC Public, Environmental & Occupational Health; General & Internal Medicine; Sport Sciences GA MW503 UT WOS:A1994MW50300003 PM 8161319 ER PT J AU MACDONALD, VW BROCKNERRYAN, BA GOMEZ, C ALAYASH, AI AF MACDONALD, VW BROCKNERRYAN, BA GOMEZ, C ALAYASH, AI TI OXIDATION OF NITROSYLHEMOGLOBIN BY OXYGEN AND OXYHEMOGLOBIN BY NITROPRUSSIDE WITHOUT PEROXIDATIVE INTERMEDIATES SO BIOPHYSICAL JOURNAL LA English DT Meeting Abstract C1 US FDA,CTR BIOL EVALUAT & RES,BETHESDA,MD 20892. USA,BLOOD RES DETACHMENT,WRAIR,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU BIOPHYSICAL SOCIETY PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0006-3495 J9 BIOPHYS J JI Biophys. J. PD FEB PY 1994 VL 66 IS 2 BP A362 EP A362 PN 2 PG 1 WC Biophysics SC Biophysics GA MU462 UT WOS:A1994MU46202099 ER PT J AU ANDREAS, EL AF ANDREAS, EL TI ON THE CONTRIBUTION OF SPRAY DROPLETS TO EVAPORATION - COMMENTS SO BOUNDARY-LAYER METEOROLOGY LA English DT Article ID ATMOSPHERIC SURFACE-LAYER; SIZE DISTRIBUTIONS; SEA SPRAY; AEROSOL; OCEAN RP USA, COLD REG RES & ENGN LAB, 72 LYME RD, HANOVER, NH 03755 USA. NR 32 TC 6 Z9 6 U1 0 U2 1 PU SPRINGER PI DORDRECHT PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS SN 0006-8314 EI 1573-1472 J9 BOUND-LAY METEOROL JI Bound.-Layer Meteor. PD FEB PY 1994 VL 68 IS 1-2 BP 207 EP 214 DI 10.1007/BF00712673 PG 8 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA NJ272 UT WOS:A1994NJ27200012 ER PT J AU WERRLEIN, RJ MADRENWHALLEY, JS KIRBY, SD AF WERRLEIN, RJ MADRENWHALLEY, JS KIRBY, SD TI PHOSGENE EFFECTS ON F-ACTIN ORGANIZATION AND CONCENTRATION IN CELLS CULTURED FROM SHEEP AND RAT LUNG SO CELL BIOLOGY AND TOXICOLOGY LA English DT Article DE AIRWAY EPITHELIAL CELLS; DENDRITIC CELLS; F-ACTIN; PAEC; PHOSGENE ID ANTIGEN-PRESENTING CELLS; DENDRITIC CELLS; PULMONARY; INHALATION; INJURY; MACROPHAGES; EPITHELIUM; REDUCTION; TOXICITY; EXPOSURE AB Pulmonary edema and immunosuppression of the lung are primary causes of debilitation and death from phosgene gas exposure. The pathophysiology that gives rise to these conditions shares a common clinical pathway. However, the target cells and lesions that disrupt normal barrier function and immune response of the lung are complex and poorly understood. Using confocal laser microscopy and FITC-conjugated phalloidin, we have studied the effects of phosgene on F-actin in endothelial cells from sheep pulmonary arteries and epithelial cells from rat tracheal explants. Image analyses from attached culture systems indicate that F-actin was a sensitive target molecule in both species. Exposures ranging from 0.15 to 1.0 x LCt(50) for sheep in vivo (3300 ppm.min) produced immediate, dose-dependent decreases in average F-actin content of cultured endothelial cells. Dense peripheral bands and stress fibers were diminished and partially disrupted but were not destroyed by these doses. Changes in ultrastructure and the permeability barrier of endothelial tissues included separation of basal lamina and development of paracellular leakage paths. Phosgene also decreased the F-actin in airway epithelial cells and potentiated phenotypic transformations that gave rise to progeny with dendritic processes. Differences in endothelial and airway epithelial response indicate that the cytoskeletal effects of phosgene were cell-type specific. Disruption of basal, lamina, depletion of F-actin, and development of endothelial leakage paths may contribute to decreased barrier function and increased permeability of vascular tissues. Phosgene-induced transformations that involved F-actin reorganization and appearance of dendritic cells among airway epithelia may affect other functions of the lung. RP WERRLEIN, RJ (reprint author), USA,MED RES INST CHEM DEF,PHYSIOL BRANCH,SGRD,UV,YY,ABERDEEN PROVING GROUND,MD 21010, USA. NR 32 TC 3 Z9 3 U1 0 U2 0 PU KLUWER ACADEMIC PUBL PI DORDRECHT PA SPUIBOULEVARD 50, PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS SN 0742-2091 J9 CELL BIOL TOXICOL JI Cell Biol. Toxicol. PD FEB PY 1994 VL 10 IS 1 BP 45 EP 58 DI 10.1007/BF00757186 PG 14 WC Cell Biology; Toxicology SC Cell Biology; Toxicology GA NJ291 UT WOS:A1994NJ29100004 PM 8076222 ER PT J AU EISENHAUER, MD ELIASSON, AH TAYLOR, AJ COYNE, PE WORTHAM, DC AF EISENHAUER, MD ELIASSON, AH TAYLOR, AJ COYNE, PE WORTHAM, DC TI INCIDENCE OF CARDIAC-ARRHYTHMIAS DURING INTRAVENOUS PENTAMIDINE THERAPY IN HIV-INFECTED PATIENTS SO CHEST LA English DT Article ID TORSADES-DE-POINTES; PNEUMOCYSTIS-CARINII PNEUMONIA; VENTRICULAR-TACHYCARDIA; QT INTERVAL; PANCREATITIS; ISETHIONATE AB Study objective: There have been 15 published cases of probable pentamidine-induced torsade de pointes (TdP). A prospective analysis of this complication of therapy is valuable considering the high frequency of Pneumocystis carinii pneumonia in the AIDS population, and the role of pentamidine in its therapy. Design: Open, nonrandomized, prospective study of HIV-infected patients receiving intravenous pentamidine in a 12-month period. Setting: Walter Reed Army Medical Center, a tertiary care, referral-based facility in Washington, DC. Patients: Eighteen HIV-infected patients were enrolled with informed consent; four were withdrawn from statistical analysis after receiving only one or two doses of empiric intravenously administered pentamidine. Measurements and results: Daily 12-lead electrocardiography, echocardiography, weekly signal-averaged electrocardiography, and weekly 24-h ambulatory electrocardiography were performed on each patient. Of the 14 subjects, 3 developed TdP. These 3 patients and 2 others developed a prolonged rate corrected, QT interval (QTc) to greater than 0.48 s (max QTc mean, 0.55 s, mean increase, 0.12 s). The QTc prolongation was noted in all five patients by the fourth daily dose (4 mg/kg/d) of pentamidine. The other 9 patients developed minimal change in QTc intervals throughout therapy (max QTc mean, 0.45 s; mean increase, 0.03 s). The maximum QTc increase was significantly different between these two cohorts (p < 0.03). The occurrence of TdP in the subgroup of patients developing prolonged QTc intervals to greater than 0.48 s (3 of 5 patients), or a change in QTc of greater than 0.08 s (3 of 4 patients) over individual baseline also was significant (p = 0.03 and p = 0.01, respectively). No baseline clinical variables associated with TdP or QTc prolongation were identified. Conclusion: Intravenously administered pentamidine frequently results in QTc prolongation with a subsequent risk of TdP in HIV-infected patients. Ah patients treated with intravenously administered pentamidine should be evaluated with baseline and daily ECGs, at least during the first week of therapy, and should be closely monitored for a change in the QT interval. An increase in QTc to above 0.48 s or greater than 0.08 s above baseline carries a significant risk for proarrhythmia, and in this instance, continuous electrocardiographic monitoring or an alternative antibiotic regimen should be considered. C1 WALTER REED ARMY MED CTR,DEPT CLIN INVEST,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,DEPT MED,WASHINGTON,DC 20307. UNIFORMED SERV UNIV HLTH SCI,BETHESDA,MD 20814. NR 40 TC 56 Z9 60 U1 0 U2 0 PU AMER COLL CHEST PHYSICIANS PI NORTHBROOK PA 3300 DUNDEE ROAD, NORTHBROOK, IL 60062-2348 SN 0012-3692 J9 CHEST JI Chest PD FEB PY 1994 VL 105 IS 2 BP 389 EP 395 DI 10.1378/chest.105.2.389 PG 7 WC Critical Care Medicine; Respiratory System SC General & Internal Medicine; Respiratory System GA MX262 UT WOS:A1994MX26200019 PM 8306734 ER PT J AU ARGYROS, MGJ TORRINGTON, KG AF ARGYROS, MGJ TORRINGTON, KG TI FIBEROPTIC BRONCHOSCOPY IN THE EVALUATION OF CARCINOMA METASTATIC TO THE LUNG SO CHEST LA English DT Article ID NON-HODGKINS LYMPHOMA; KAPOSIS SARCOMA; AIDS AB To determine the clinical presentation of patients with malignancies metastatic to the lung, the diagnostic utility of fiberoptic bronchoscopy (FB), and the primary site of malignancies metastasizing endobronchially, we retrospectively reviewed 1,853 FB records (1987 to 1991) and selected 111 cases for review Cases were divided on the basis of FB findings into abnormal (44 patients) and normal (67 patients). Pulmonary symptoms (cough, hemoptysis, and chest pain) prompted referral significantly more often in the abnormal FB group (34/44) than in the normal FB group (24/67). The finding of atelectasis on chest radiograph occurred more frequently in patients with endobronchial abnormalities. The spectrum of extrapulmonary malignancies that metastasize endobronchially has changed during the AIDS epidemic. Our study shows the most frequent causes of endobronchial mass lesions were Kaposi's sarcoma and the lymphoma group (Hodgkin's disease, nonHodgkin's lymphoma, chronic lymphocytic leukemia) and the most common malignancies causing submucosal metastases were breast and the lymphoma group. In summary, the highest yield for FB can be expected in patients experiencing symptoms of cough of hemoptysis and/or having radiographic evidence of atelectasis. We propose a new mnemonic ''KLAS'' (Kaposi's sarcoma, Lymphoma, Adenocarcinoma, Sarcoma) to describe the malignancies most likely to metastasize endobronchially in the 1990s. C1 WALTER REED ARMY MED CTR,DEPT MED,PULM & CRIT CARE MED SERV,WASHINGTON,DC 20307. NR 15 TC 12 Z9 12 U1 0 U2 0 PU AMER COLL CHEST PHYSICIANS PI NORTHBROOK PA 3300 DUNDEE ROAD, NORTHBROOK, IL 60062-2348 SN 0012-3692 J9 CHEST JI Chest PD FEB PY 1994 VL 105 IS 2 BP 454 EP 457 PG 4 WC Critical Care Medicine; Respiratory System SC General & Internal Medicine; Respiratory System GA MX262 UT WOS:A1994MX26200032 ER PT J AU DOOLEY, DP TOMSKI, S AF DOOLEY, DP TOMSKI, S TI SYPHILITIC PNEUMONITIS IN AN HIV-INFECTED PATIENT SO CHEST LA English DT Note ID SECONDARY SYPHILIS; INVOLVEMENT AB Pneumonitis and symptomatic hepatitis are very rare complications of syphilis. Symptomatic hepatitis and subclinical reticulonodular pulmonary infiltrates were observed when an HIV-infected patient presented with secondary syphilis. The Jarisch-Herxheimer reaction included a flare of hepatitis symptoms, resembling cholangitis. In a patient with syphilis, it may be appropriate to delay an aggressive evaluation for suspected pneumonitis or cholangitis pending the outcome of specific antitreponemal therapy. C1 BROOKE ARMY MED CTR,DEPT MED,FT SAM HOUSTON,TX 78234. WILFORD HALL USAF MED CTR,LACKLAND AFB,TX. NR 24 TC 9 Z9 10 U1 0 U2 0 PU AMER COLL CHEST PHYSICIANS PI NORTHBROOK PA 3300 DUNDEE ROAD, NORTHBROOK, IL 60062-2348 SN 0012-3692 J9 CHEST JI Chest PD FEB PY 1994 VL 105 IS 2 BP 629 EP 631 DI 10.1378/chest.105.2.629 PG 3 WC Critical Care Medicine; Respiratory System SC General & Internal Medicine; Respiratory System GA MX262 UT WOS:A1994MX26200073 PM 8306785 ER PT J AU TENHOLDER, MF WHITLOCK, WL AF TENHOLDER, MF WHITLOCK, WL TI IS CHEST CT PERFORMED TOO OFTEN SO CHEST LA English DT Letter C1 EISENHOWER ARMY MED CTR,DIV PULM,FT GORDON,GA. RP TENHOLDER, MF (reprint author), VET ADM MED CTR,PULM DIS SECT,AUGUSTA,GA, USA. NR 4 TC 0 Z9 0 U1 0 U2 0 PU AMER COLL CHEST PHYSICIANS PI NORTHBROOK PA 3300 DUNDEE ROAD, NORTHBROOK, IL 60062-2348 SN 0012-3692 J9 CHEST JI Chest PD FEB PY 1994 VL 105 IS 2 BP 647 EP 648 PG 2 WC Critical Care Medicine; Respiratory System SC General & Internal Medicine; Respiratory System GA MX262 UT WOS:A1994MX26200093 PM 8306799 ER PT J AU THAITHUMYANON, P THISYAKORN, U DEEROJNAWONG, J INNIS, BL AF THAITHUMYANON, P THISYAKORN, U DEEROJNAWONG, J INNIS, BL TI DENGUE INFECTION COMPLICATED BY SEVERE HEMORRHAGE AND VERTICAL TRANSMISSION IN A PARTURIENT WOMAN SO CLINICAL INFECTIOUS DISEASES LA English DT Note AB A Thai woman with a febrile illness was delivered of a healthy infant by cesarean section. The etiology of her 2-day fever was unknown at the time of surgery; results of serology performed later established a diagnosis of dengue infection. Postoperative hemostatic monitoring was not performed. She experienced massive and prolonged (8 days) wound hemorrhage that necessitated multiple transfusions of blood, platelets, and frozen plasma. The newborn became febrile on his 6th day of life. Dengue virus type 2 was isolated from his serum. Although the infant developed marked thrombocytopenia, his illness was brief and uncomplicated. This report emphasizes the hazards of surgical intervention in patients with acute dengue infection. We also believe it to be the first report of vertical transmission of dengue in humans. C1 CHULALONGKORN UNIV,FAC MED,DEPT PEDIAT,BANGKOK 10330,THAILAND. ARMED FORCES RES INST MED SCI,DEPT VIROL,BANGKOK,THAILAND. NR 5 TC 35 Z9 40 U1 0 U2 2 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 1058-4838 J9 CLIN INFECT DIS JI Clin. Infect. Dis. PD FEB PY 1994 VL 18 IS 2 BP 248 EP 249 PG 2 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA MU350 UT WOS:A1994MU35000019 PM 8161636 ER PT J AU HONIG, P SMITH, J WORTHAM, D ZAMANI, K CANTILENA, L AF HONIG, P SMITH, J WORTHAM, D ZAMANI, K CANTILENA, L TI PHARMACOKINETIC VARIABILITY OF TERFENADINE BIOTRANSFORMATION IN HEALTHY-VOLUNTEERS SO CLINICAL PHARMACOLOGY & THERAPEUTICS LA English DT Meeting Abstract C1 USUHS,DIV CLIN PHARMACOL,BETHESDA,MD. WALTER REED ARMY MED CTR,DEPT CARDIOL,WASHINGTON,DC 20307. RI Zamani, Kaveh/A-9182-2011 NR 0 TC 0 Z9 0 U1 0 U2 0 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0009-9236 J9 CLIN PHARMACOL THER JI Clin. Pharmacol. Ther. PD FEB PY 1994 VL 55 IS 2 BP 138 EP 138 PG 1 WC Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA MY421 UT WOS:A1994MY42100061 ER PT J AU HONIG, P WORTHAM, D HULL, R ZAMANI, K SMITH, J CANTILENA, L AF HONIG, P WORTHAM, D HULL, R ZAMANI, K SMITH, J CANTILENA, L TI ITRACONAZOLE AFFECTS SINGLE-DOSE, TERFENADINE PHARMACOKINETICS AND CARDIAC REPOLARIZATION PHARMACODYNAMICS SO CLINICAL PHARMACOLOGY & THERAPEUTICS LA English DT Meeting Abstract C1 USUHS,DIV CLIN PHARMACOL,BETHESDA,MD. WALTER REED ARMY MED CTR,DEPT CARDIOL,WASHINGTON,DC. RI Zamani, Kaveh/A-9182-2011 NR 0 TC 2 Z9 2 U1 0 U2 0 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0009-9236 J9 CLIN PHARMACOL THER JI Clin. Pharmacol. Ther. PD FEB PY 1994 VL 55 IS 2 BP 165 EP 165 PG 1 WC Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA MY421 UT WOS:A1994MY42100168 ER PT J AU LI, QG PEGGINS, JO FLECKENSTEIN, L BREWER, TG AF LI, QG PEGGINS, JO FLECKENSTEIN, L BREWER, TG TI BINDING OF C-14 ARTELINATE AND C-14 DIHYDROARTEMISININ TO HUMAN AND ANIMAL PLASMA-PROTEIN SO CLINICAL PHARMACOLOGY & THERAPEUTICS LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DEPT PHARMACOL,DIV EXPTL THERAPEUT,WASHINGTON,DC. UNIV IOWA,COLL PHARM,IOWA CITY,IA 52242. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0009-9236 J9 CLIN PHARMACOL THER JI Clin. Pharmacol. Ther. PD FEB PY 1994 VL 55 IS 2 BP 166 EP 166 PG 1 WC Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA MY421 UT WOS:A1994MY42100174 ER PT J AU GRIFFISS, JM WANG, J ZHAO, S SCHNEIDER, H AF GRIFFISS, JM WANG, J ZHAO, S SCHNEIDER, H TI NEISSERIA-GONORRHOEAE MUST EXPRESS GANGLIOSIDE-LIKE LIPOOLIGOSACCHARIDES (LOS) TO INVADE CERVICAL EPITHELIAL-CELLS SO CLINICAL RESEARCH LA English DT Meeting Abstract C1 UNIV CALIF SAN FRANCISCO,SAN FRANCISCO,CA 94143. WALTER REED ARMY INST RES,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 SN 0009-9279 J9 CLIN RES JI Clin. Res. PD FEB PY 1994 VL 42 IS 1 BP A84 EP A84 PG 1 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA MR214 UT WOS:A1994MR21400451 ER PT J AU HUNTER, P GALLAGHER, T AF HUNTER, P GALLAGHER, T TI PALLISTER-HALL SYNDROME IN SIBLINGS - A CASE-REPORT AND REVIEW OF THE LITERATURE SO CLINICAL RESEARCH LA English DT Meeting Abstract C1 TRIPLER ARMY MED CTR,DEPT PEDIAT,HONOLULU,HI 96859. NR 0 TC 3 Z9 3 U1 0 U2 0 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 SN 0009-9279 J9 CLIN RES JI Clin. Res. PD FEB PY 1994 VL 42 IS 1 BP A52 EP A52 PG 1 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA MR214 UT WOS:A1994MR21400277 ER PT J AU IWAMOTO, LM AYAU, EL WILSON, VL NAKAMURA, KT AF IWAMOTO, LM AYAU, EL WILSON, VL NAKAMURA, KT TI DESENSITIZATION TO FUROSEMIDE IN GUINEA-PIG AIRWAY SMOOTH-MUSCLE SO CLINICAL RESEARCH LA English DT Meeting Abstract C1 UNIV HAWAII,KAPIOLANI MED CTR,DEPT PEDIAT,HONOLULU,HI 96822. UNIV HAWAII,TRIPLER ARMY MED CTR,DEPT CLIN INVEST,HONOLULU,HI 96822. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 SN 0009-9279 J9 CLIN RES JI Clin. Res. PD FEB PY 1994 VL 42 IS 1 BP A34 EP A34 PG 1 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA MR214 UT WOS:A1994MR21400179 ER PT J AU SOOD, SL FINN, KC MUNDIE, TG EASA, D AF SOOD, SL FINN, KC MUNDIE, TG EASA, D TI EFFECTS OF EXOGENOUS SURFACTANT, EXOSURF(R), ON THE PULMONARY AND HEMODYNAMIC STATUS OF THE NEONATAL PIGLET TREATED WITH ENDOTOXIN SO CLINICAL RESEARCH LA English DT Meeting Abstract C1 UNIV HAWAII,KAPIOLANI MED CTR,TRIPLER ARMY MED CTR,HONOLULU,HI 96822. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 SN 0009-9279 J9 CLIN RES JI Clin. Res. PD FEB PY 1994 VL 42 IS 1 BP A34 EP A34 PG 1 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA MR214 UT WOS:A1994MR21400180 ER PT J AU MITTAL, S TEZDUYAR, TE AF MITTAL, S TEZDUYAR, TE TI MASSIVELY-PARALLEL FINITE-ELEMENT COMPUTATION OF INCOMPRESSIBLE FLOWS INVOLVING FLUID-BODY INTERACTIONS SO COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING LA English DT Article; Proceedings Paper CT 1st US-Japan Symposium on Finite Element Methods in Large-Scale Computational Fluid Dynamics CY OCT 11-14, 1992 CL UNIV MINNESOTA SUPERCOMP INST, MINNEAPOLIS, MN SP UNIV MINNESOTA SUPERCOMP INST, USA HIGH PERFORMANCE COMP RES INST, THINKING MACHINES CORP HO UNIV MINNESOTA SUPERCOMP INST ID NAVIER-STOKES EQUATIONS; FORMULATION; DYNAMICS AB We describe our massively parallel finite element computations of unsteady incompressible flows involving fluid-body interactions. These computations are based on the Deforming-Spatial-Domain/Stabilized-Space-Time (DSD/SST) finite element formulation. Unsteady flows past a stationary NACA 0012 airfoil are computed for Reynolds numbers 1000, 5000 and 100000. Significantly different flow patterns are observed for these three cases. The method is then applied to computation of the dynamics of an airfoil falling in a viscous fluid under the influence of gravity. It is observed that the location of the center of gravity of the airfoil plays an important role in determining its pitch stability. Computations are reported also for simulation of the dynamics of a two-dimensional 'projectile' that has a certain initial velocity. Specially designed mesh moving schemes are employed to eliminate the need for remeshing. All these computations were carried out on the Thinking Machines CM-200 and CM-5 supercomputers, with major speed-ups compared to traditional supercomputers. The implicit equation systems arising from the finite element discretizations of these large-scale problems are solved iteratively by using the GMRES update technique with diagonal preconditioners. The finite element formulations and their parallel implementations assume unstructured meshes. C1 UNIV MINNESOTA,INST SUPERCOMP,MINNEAPOLIS,MN 55415. UNIV MINNESOTA,ARMY HIGH PERFORMANCE COMP RES CTR,DEPT AEROSP ENGN & MECH,MINNEAPOLIS,MN 55415. RI Tezduyar, Tayfun/F-6134-2012 OI Tezduyar, Tayfun/0000-0001-8707-3162 NR 16 TC 72 Z9 73 U1 0 U2 5 PU ELSEVIER SCIENCE SA LAUSANNE PI LAUSANNE 1 PA PO BOX 564, 1001 LAUSANNE 1, SWITZERLAND SN 0045-7825 J9 COMPUT METHOD APPL M JI Comput. Meth. Appl. Mech. Eng. PD FEB PY 1994 VL 112 IS 1-4 BP 253 EP 282 DI 10.1016/0045-7825(94)90029-9 PG 30 WC Engineering, Multidisciplinary; Mathematics, Interdisciplinary Applications; Mechanics SC Engineering; Mathematics; Mechanics GA MX764 UT WOS:A1994MX76400015 ER PT J AU SPRUNG, CL DANIS, M ARMSTRONG, C BAILEY, MA DAGI, TF ENGELHARDT, HT GRENVIK, A HOFMANN, P HOYT, JW JAMETON, A KOFKE, WA LYNN, J MARSHALL, MF MCCARTNEY, JJ NELSON, R NINOS, NP PEDUZZI, P RAPHAELY, RC RIE, MA ROSENBAUM, SH SOTTILLE, FD SPANIER, A STEINBERG, A TENDLER, MD TERES, D TRUOG, RD WALLACE, T YEH, TS AF SPRUNG, CL DANIS, M ARMSTRONG, C BAILEY, MA DAGI, TF ENGELHARDT, HT GRENVIK, A HOFMANN, P HOYT, JW JAMETON, A KOFKE, WA LYNN, J MARSHALL, MF MCCARTNEY, JJ NELSON, R NINOS, NP PEDUZZI, P RAPHAELY, RC RIE, MA ROSENBAUM, SH SOTTILLE, FD SPANIER, A STEINBERG, A TENDLER, MD TERES, D TRUOG, RD WALLACE, T YEH, TS TI ATTITUDES OF CRITICAL CARE MEDICINE PROFESSIONALS CONCERNING DISTRIBUTION OF INTENSIVE-CARE RESOURCES SO CRITICAL CARE MEDICINE LA English DT Article DE ETHICS; CRITICAL CARE; TRIAGE; ADMISSION CRITERIA; ALLOCATION OF RESOURCES; VEGETATIVE STATE; TERMINAL ILLNESS; INTENSIVE CARE UNITS; RATIONING OF SERVICES AB Objective: To determine critical care practitioners' attitudes about the importance of various factors in decisions to use intensive care, including age, prognosis, quality of life, patient preference, and medical condition. Design: Cohort study. Setting: The Annual Educational and Scientific Symposium of the Society of Critical Care Medicine. Subjects: Participants at the symposium. Results: A self-administered questionnaire was distributed and 600 (52%) of 1,148 registrants attending the symposium responded. Eighty-four percent of respondents were physicians and 11% were nurses. Physicians were internists (30%), surgeons (24%), pediatricians (22%), and anesthesiologists (19%); 58% were in academic practices. Very few respondents believed that age should be a criterion for limiting intensive care (12%). Quality of life as viewed by the patient, probability of surviving hospitalization, reversibility of the acute disorder, and nature of the chronic disorder were the factors that most respondents considered to be important in decisions to admit to the intensive care unit. The patient's social worth, previous psychiatric history, cost-benefit analysis, and cost to society were the factors most respondents considered of little importance. Over 40% of respondents would admit patients with a chronic vegetative state or a patient with metastatic carcinoma and a superimposed, life-threatening event. Conclusions: These results suggest that critical care providers, who must occasionally face difficult decisions about how to distribute limited resources among patients with competing needs, were not often inclined, at the time of this survey, to make choices based on estimates of who might benefit most. These critical care physicians' attitudes about triage may not support the optimal use of critical care resources. C1 HEBREW UNIV JERUSALEM, HADASSAH MED SCH, IL-91010 JERUSALEM, ISRAEL. UNIV N CAROLINA, CHAPEL HILL, NC USA. APPEALS COURT COMMONWEALTH MASSACHUSETTS, BOSTON, MA USA. GEORGE WASHINGTON UNIV, WASHINGTON, DC USA. GEORGETOWN UNIV, KENNEDY INST ETH, WASHINGTON, DC 20057 USA. BAYLOR COLL MED, HOUSTON, TX 77030 USA. UNIV PITTSBURGH, SCH MED, PITTSBURGH, PA USA. STANFORD UNIV, CTR BIOMED ETH, STANFORD, CA USA. ST FRANCIS MED CTR, PITTSBURGH, PA USA. UNIV NEBRASKA, MED CTR, OMAHA, NE USA. DARTMOUTH COLL, SCH MED, HANOVER, NH USA. UNIV VIRGINIA, SCH MED, CHARLOTTESVILLE, VA 22908 USA. VILLANOVA UNIV, VILLANOVA, PA 19085 USA. MED COLL WISCONSIN, MILWAUKEE, WI 53226 USA. USA, MED CORPS, WASHINGTON, DC USA. VET AFFAIRS MED CTR, W HAVEN, CT USA. CHILDRENS HOSP PHILADELPHIA, PHILADELPHIA, PA 19104 USA. UNIV KENTUCKY, LEXINGTON, KY USA. YALE UNIV, SCH MED, NEW HAVEN, CT USA. ST VINCENTS HOSP & MED CTR, NEW YORK, NY 10011 USA. JEWISH GEN HOSP, MONTREAL, PQ, CANADA. HEBREW UNIV JERUSALEM, JERUSALEM, ISRAEL. YESHIVA UNIV, NEW YORK, NY 10033 USA. HARVARD UNIV, SCH MED, CAMBRIDGE, MA 02138 USA. UNIV TENNESSEE, MEMPHIS, TN USA. CHILDRENS HOSP OAKLAND, OAKLAND, CA USA. BAYSTATE MED CTR, SPRINGFIELD, MA USA. NR 7 TC 43 Z9 45 U1 0 U2 0 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0090-3493 EI 1530-0293 J9 CRIT CARE MED JI Crit. Care Med. PD FEB PY 1994 VL 22 IS 2 BP 358 EP 362 PG 5 WC Critical Care Medicine SC General & Internal Medicine GA MX505 UT WOS:A1994MX50500031 ER PT J AU MCCLURE, MT VONWINDHEIM, JA GLASS, JT PRATER, JT AF MCCLURE, MT VONWINDHEIM, JA GLASS, JT PRATER, JT TI EFFECT OF NATIVE SIO2 LAYER ON THE NUCLEATION OF DIAMOND USING A COMBUSTION-FLAME SO DIAMOND AND RELATED MATERIALS LA English DT Article ID CHEMICAL VAPOR-DEPOSITION; OXYACETYLENE FLAME; AREA DEPOSITION; ACETYLENE TORCH; SILICON; GROWTH; FILMS AB The effect of native oxide thickness on the nucleation of diamond was investigated. The initial thickness of the native oxide on Si substrates was varied using three surface treatment methods: ultrasonic scratching, HF acid etching, and a combination of the two. The oxide layer was also modified during the experiment by using a low O-2:C2H2 ratio pregrowth treatment (R(f)=0.93, d=15 mm). The use of HF acid eliminated the oxide layer within the detectable limits of the X-ray photoelectron spectroscopy analysis (about 3 Angstrom). A low gas ratio pregrowth treatment process (oxygen-to-acetylene ratio R(f), set to 0.93) meant that diamond crystals were formed after 30 s and a complete him in the center of the deposition area after 180 s. The low gas ratio pregrowth treatment suppressed the formation of the oxide layer relative to standard growth conditions (R(f)=0.97, d=10 mm). However, it was determined that despite this low gas ratio treatment SiO2 formation was possible inside the acetylene feather. C1 USA,RES OFF,RES TRIANGLE PK,NC 27709. RP MCCLURE, MT (reprint author), N CAROLINA STATE UNIV,DEPT MAT SCI & ENGN,RALEIGH,NC 27695, USA. RI Glass, Jeffrey/A-2266-2010 OI Glass, Jeffrey/0000-0002-9554-4398 NR 28 TC 3 Z9 3 U1 0 U2 0 PU ELSEVIER SCIENCE SA LAUSANNE PI LAUSANNE 1 PA PO BOX 564, 1001 LAUSANNE 1, SWITZERLAND SN 0925-9635 J9 DIAM RELAT MATER JI Diam. Relat. Mat. PD FEB PY 1994 VL 3 IS 3 BP 239 EP 244 DI 10.1016/0925-9635(94)90086-8 PG 6 WC Materials Science, Multidisciplinary SC Materials Science GA MW909 UT WOS:A1994MW90900008 ER PT J AU DAVENPORT, R JOHNSON, LR SCHAEFFER, DJ BALBACH, H AF DAVENPORT, R JOHNSON, LR SCHAEFFER, DJ BALBACH, H TI PHOTOTOXICOLOGY .1. LIGHT-ENHANCED TOXICITY OF TNT AND SOME RELATED-COMPOUNDS TO DAPHNIA-MAGNA AND LYTECHINUS-VARIAGATUS EMBRYOS SO ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY LA English DT Article ID POLYCYCLIC AROMATIC-HYDROCARBONS; PHOTOINDUCED TOXICITY; ANTHRACENE AB Many environmental pollutants interact with solar near-ultraviolet (nuv) light in a manner which greatly increases their toxic effects. The phenomenon of light-mediated toxicity (phototoxicity) is only now becoming generally recognized to any significant degree. Manufacture of, and loading munitions with, the explosive 2,4,6-trinitrotoluene (TNT) in past decades caused contamination of soils and sediments at levels exceeding 1000 ppm and of waters at levels near saturation (100 ppm). Manufacture of TNT produces numerous nitrated by-products, and most of these compounds, including TNT, can be metabolized by many species, including bacteria, fungi, plants, and mammals. This study investigated the phototoxicity of TNT, and 2,3-, 2,4-, 2,6-, and 3,4-dinitrotoluene (DNT) and -diaminotoluene (DAT), and the major metabolites 2-amino-4,6-dinitrotoruene (2A) and 4-amino-2,6-dinitrotoluene (4A), to Daphnia magna (acute toxicity) and Lytechinus variagatus (sea urchin) embryos (subacute, developmental toxicity). Most of the compounds were weakly toxic or nontoxic in the dark. All were phototoxic to sea urchins. In D. magna, 2,3- and 3,4-DNT/DAT and 4A were not toxic but were phototoxic, and 2A was toxic and phototoxic; the other isomers were not toxic or phototoxic to this species. (C) 1994 Academic Press, Inc. C1 UNIV ILLINOIS,DEPT VET BIOSCI,URBANA,IL 61801. USA,CONSTRUCT ENGN RES LAB,CHAMPAIGN,IL 61824. RP DAVENPORT, R (reprint author), UNIV ILLINOIS,SCH LIFE SCI,506 S GOODWIN AVE,URBANA,IL 61801, USA. NR 19 TC 25 Z9 27 U1 1 U2 5 PU ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 SN 0147-6513 J9 ECOTOX ENVIRON SAFE JI Ecotox. Environ. Safe. PD FEB PY 1994 VL 27 IS 1 BP 14 EP 22 DI 10.1006/eesa.1994.1003 PG 9 WC Environmental Sciences; Toxicology SC Environmental Sciences & Ecology; Toxicology GA MY424 UT WOS:A1994MY42400003 PM 7525201 ER PT J AU JOHNSON, LR DAVENPORT, R BALBACH, H SCHAEFFER, DJ AF JOHNSON, LR DAVENPORT, R BALBACH, H SCHAEFFER, DJ TI PHOTOTOXICOLOGY .2. NEAR-ULTRAVIOLET LIGHT ENHANCEMENT OF MICROTOX ASSAYS OF TRINITROTOLUENE AND AMINODINITROTOLUENES SO ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY LA English DT Article ID POLYCYCLIC AROMATIC-HYDROCARBONS; CHROMATOGRAPHY MASS-SPECTROMETRY; PHOTOENHANCED TOXICITY; DAPHNIA-MAGNA; PHOTOINDUCED TOXICITY; SUNFISH LEPOMIS; ANTHRACENE; 2,4,6-TRINITROTOLUENE; METABOLITES; EXPLOSIVES AB Coexposure of 2,4,6-trinitrotoluene (TNT), 2-amino-4,6-dinitrotoluene (2A), or 4-amino-2,6-dinitrotoluene (4A) to near-ultraviolet (nuv) light (lambda(max)-354 nm) significantly enhanced their toxicity toward Photobacterium phosphoreum (Microtox bioassay) during 30 min but not 15 min. Based on the slopes of the dose-response lines, the nuv coexposure and dark toxic mechanisms of action for TNT, 2A, and 4A appeared to be similar. nuv coexposure of binary mixtures significantly enhanced (supraadditivity) the toxicity of these compounds to P. phosphoreum. Under normal laboratory lighting, the toxicity of TNT + 2A and 2A + 4A mixtures were supraadditive but the toxicity of TNT + 4A mixtures could be explained by simple addition. Supporting these conclusions, the response curves of alpha-terthienyl, a compound known not to require nuv for toxicity, were similar in the dark and with nuv coexposure. In contrast, angelicin and psoralen, compounds known to require nuv coexposure to damage DNA, gave response curves having different slopes in the dark and with nuv coexposure. The nuv coexposure Microtox assay was able to detect and quantify phototoxicity in psoralen, angelicin, alpha-terthienyl, anthracene, TNT, and aminodinitrotoluenes. (C) 1994 Academic Press, Inc. C1 UNIV ILLINOIS,DEPT VET BIOSCI,URBANA,IL 61801. UNIV ILLINOIS,SCH LIFE SCI,URBANA,IL 61801. USA,CONSTRUCT ENGN RES LAB,CHAMPAIGN,IL 61824. NR 56 TC 18 Z9 18 U1 1 U2 1 PU ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 SN 0147-6513 J9 ECOTOX ENVIRON SAFE JI Ecotox. Environ. Safe. PD FEB PY 1994 VL 27 IS 1 BP 23 EP 33 DI 10.1006/eesa.1994.1004 PG 11 WC Environmental Sciences; Toxicology SC Environmental Sciences & Ecology; Toxicology GA MY424 UT WOS:A1994MY42400004 PM 7525202 ER PT J AU JOHNSON, LR DAVENPORT, R BALBACH, H SCHAEFFER, DJ AF JOHNSON, LR DAVENPORT, R BALBACH, H SCHAEFFER, DJ TI PHOTOTOXICOLOGY .3. COMPARATIVE TOXICITY OF TRINITROTOLUENE AND AMINODINITROTOLUENES TO DAPHNIA-MAGNA, DUGESIA-DOROTOCEPHALA, AND SHEEP ERYTHROCYTES SO ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY LA English DT Article ID POLYCYCLIC AROMATIC-HYDROCARBONS; PHOTOENHANCED TOXICITY; NITROAROMATIC COMPOUNDS; PHOTOINDUCED TOXICITY; SUNFISH LEPOMIS; ANTHRACENE; 2,4,6-TRINITROTOLUENE; TRANSFORMATION; TNT AB 2,4,6-Trinitrotoluene (TNT) and compounds associated with its production are toxic and phototoxic to a wide range of biota. The planarian Dugesia dorotocephala, but not Daphnia magna, metabolized TNT (1 mg/liter) to 4-amino-2,6-dinitrotoluene (4A; 0.4 mg/liter) and 2-amino-4,6-dinitrotoluene (2A; 0.2 mg/liter). Coexposure to near-ultraviolet (nuv) light enhanced the toxicity of 2A more than that of TNT and 4A. The toxicities of TNT, 4A, and 2A to Du. dorotocephala were all decreased by glutathione (GSH) conjugation. This suggests that all had mechanisms of toxic action involving formation of quinone-GSH conjugates. Dark and light mechanisms for TNT and 2A depended on GSH conjugation, but the specific mechanisms may be different for each compound. The dark and light mechanisms of toxic action for 4A appeared to be fundamentally different in that the dark toxic mechanism of action was less dependent on GSH conjugation. Hemolysis studies using sheep erythrocytes showed that the light-enhanced toxic mechanism of action for TNT, 2A, and/or 4A did not involve cellular membrane damage in response to nuv-induced anions. (C) 1994 Academic Press, Inc. C1 UNIV ILLINOIS,DEPT VET BIOSCI,URBANA,IL 61801. UNIV ILLINOIS,SCH LIFE SCI,URBANA,IL 61801. USA,CONSTRUCT ENGN RES LAB,CHAMPAIGN,IL 61824. NR 44 TC 18 Z9 20 U1 0 U2 4 PU ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 SN 0147-6513 J9 ECOTOX ENVIRON SAFE JI Ecotox. Environ. Safe. PD FEB PY 1994 VL 27 IS 1 BP 34 EP 49 DI 10.1006/eesa.1994.1005 PG 16 WC Environmental Sciences; Toxicology SC Environmental Sciences & Ecology; Toxicology GA MY424 UT WOS:A1994MY42400005 PM 7525203 ER PT J AU NAGATANI, S MATHIEU, GP AF NAGATANI, S MATHIEU, GP TI PARTIALLY ARRESTED ROOT-FORMATION IN A PERMANENT MAXILLARY CENTRAL INCISOR SUBSEQUENT TO TRAUMA TO THE PRIMARY DENTITION SO ENDODONTICS & DENTAL TRAUMATOLOGY LA English DT Note DE TOOTH ROOT; TOOTH LUXATION; DENTAL INJURY AB When the primary dentition sustains a traumatic insult, the development of the succedaneous teeth can be disturbed leading to a number of malformations. In this case report, the patient presented with a history of prior trauma to his primary maxillary incisors which resulted in partially arrested root formation for a permanent incisor. The considerations in formulating a treatment plan which included orthodontics are discussed. RP NAGATANI, S (reprint author), USA,DENT ACTIV,PEDIAT DENT RESIDENCY PROGRAM,FT GEORGE G MEADE,MD 20755, USA. NR 0 TC 3 Z9 3 U1 0 U2 0 PU MUNKSGAARD INT PUBL LTD PI COPENHAGEN PA 35 NORRE SOGADE, PO BOX 2148, DK-1016 COPENHAGEN, DENMARK SN 0109-2502 J9 ENDOD DENT TRAUMATOL JI Endod. Dent. Traumatol. PD FEB PY 1994 VL 10 IS 1 BP 23 EP 26 PG 4 WC Dentistry, Oral Surgery & Medicine SC Dentistry, Oral Surgery & Medicine GA NA682 UT WOS:A1994NA68200005 PM 8005076 ER PT J AU BUCCI, TJ WUSTENBERG, W PERMAN, V WEISS, DJ DACRE, JC BAUMEL, IP PARKER, RM AF BUCCI, TJ WUSTENBERG, W PERMAN, V WEISS, DJ DACRE, JC BAUMEL, IP PARKER, RM TI SUBCHRONIC ORAL TOXICITY STUDY OF DIISOPROPYL METHYLPHOSPHONATE IN MINK SO FUNDAMENTAL AND APPLIED TOXICOLOGY LA English DT Article AB Diisopropyl methylphosphonate (DIMP), produced during manufacture of the chemical agent GB (Sarin), is a groundwater contaminant at Rocky Mountain Arsenal, Colorado. DIMP was fed for 90 days to dark brown ''Ranch Wild'' mink housed under controlled indoor conditions. One-year-old mink, 10 of each sex, were fed 0, 50, 450, 2700, 5400, or 8000 ppm in standard ranch diet. Actual DIMP consumption was 0, 8, 73, 400, 827, and 1136 mg/kg body wt/day, respectively. Two additional groups of 10 served as ''pair-fed'' controls. Body weight and food intake were recorded weekly. Complete blood count and 15 chemical analytes were measured at Weeks 0, 3, 7, and 13. Necropsy and microscopic examination were performed on all mink. No clinical morbidity or deaths occurred. Both sexes fed 8000 ppm ate approximately 20% less and weighed approximately 20% less than the controls; 5400 ppm females had a 10% weight decrement. Plasma cholinesterase (ChE) decreased in the top three dose groups starting at Week 3. At 13 weeks, decrements were approximately 50% but returned to normal after 1 week without DIMP. Erythrocyte ChE was not reduced. Heinz bodies occurred in 10-15% of RBCs in 50% of 8000 ppm mink at 13 weeks, and 0.1-2.0% of RBCs in 25% at 2700 ppm. There were mild decreases in RBC count, hematocrit, and hemoglobin, and increases in reticulocyte count, at the 5400 and 8000 ppm doses. All recovered within 3 weeks after DIMP was withdrawn. The 8000 ppm group had marginal splenic hematopoiesis, histologically. No other treatment-related changes were noted. The 450 ppm dose was a clear no-effect level (approximately 73 mg DIMP/kg body wt/day). Compared to reports of similar studies of DIMP in rats and dogs, these mink displayed no unique species susceptibility. (C) 1994 Society of Toxicology. C1 USA,BIOMED RES & DEV LAB,GEOCENTERS INC,FREDERICK,MD 21702. PATHOL ASSOCIATES INC,JEFFERSON,AR 72079. VITAL HEART SYST INC,ST PAUL,MN 55458. UNIV MINNESOTA,ST PAUL,MN 55108. TSI LABS,REDFIELD,AR 72132. NR 20 TC 6 Z9 6 U1 0 U2 3 PU ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 SN 0272-0590 J9 FUND APPL TOXICOL JI Fundam. Appl. Toxicol. PD FEB PY 1994 VL 22 IS 2 BP 220 EP 230 DI 10.1006/faat.1994.1026 PG 11 WC Toxicology SC Toxicology GA MZ249 UT WOS:A1994MZ24900007 PM 8005374 ER PT J AU SJOGREN, R NEILL, R RACHMILEWITZ, D FRITZ, D NEWLAND, J SHARPNACK, D COLLETON, C FONDACARO, J GEMSKI, P BOEDEKER, E AF SJOGREN, R NEILL, R RACHMILEWITZ, D FRITZ, D NEWLAND, J SHARPNACK, D COLLETON, C FONDACARO, J GEMSKI, P BOEDEKER, E TI ROLE OF SHIGA-LIKE TOXIN-I IN BACTERIAL ENTERITIS - COMPARISON BETWEEN ISOGENIC ESCHERICHIA-COLI STRAINS INDUCED IN RABBITS SO GASTROENTEROLOGY LA English DT Article ID PLATELET-ACTIVATING FACTOR; INFLAMMATORY BOWEL-DISEASE; HEMORRHAGIC COLITIS; ULCERATIVE-COLITIS; SHIGELLA TOXIN; CYTO-TOXIN; DIARRHEA; INTERLEUKIN-1; SULFASALAZINE; PATHOGENESIS C1 WALTER REED ARMY INST RES, DIV MED, WASHINGTON, DC USA. WALTER REED ARMY INST RES, DIV PATHOL, WASHINGTON, DC USA. WALTER REED ARMY INST RES, DIV COMMUNICABLE DIS & IMMUNOL, WASHINGTON, DC USA. NR 55 TC 60 Z9 62 U1 0 U2 0 PU W B SAUNDERS CO-ELSEVIER INC PI PHILADELPHIA PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA SN 0016-5085 EI 1528-0012 J9 GASTROENTEROLOGY JI Gastroenterology PD FEB PY 1994 VL 106 IS 2 BP 306 EP 317 PG 12 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA MW567 UT WOS:A1994MW56700003 PM 8299898 ER PT J AU MONTGOMERY, EA POPEK, EJ AF MONTGOMERY, EA POPEK, EJ TI INTUSSUSCEPTION, ADENOVIRUS, AND CHILDREN - A BRIEF REAFFIRMATION SO HUMAN PATHOLOGY LA English DT Article DE ADENOVIRUS; INTUSSUSCEPTION; INTESTINAL OBSTRUCTION; CHILDREN; PEDIATRIC ID NODULAR LYMPHOID HYPERPLASIA; PEUTZ-JEGHERS SYNDROME; CYSTIC-FIBROSIS; NEOPLASMS; ROTAVIRUS; TRACT C1 USA,INST PATHOL,DEPT PEDIAT PATHOL,WASHINGTON,DC 20310. RP MONTGOMERY, EA (reprint author), GEORGETOWN UNIV,DEPT PATHOL,BASIC SCI BLDG,3900 RESERVOIR RD NW,WASHINGTON,DC 20007, USA. NR 34 TC 52 Z9 52 U1 1 U2 2 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0046-8177 J9 HUM PATHOL JI Hum. Pathol. PD FEB PY 1994 VL 25 IS 2 BP 169 EP 174 DI 10.1016/0046-8177(94)90274-7 PG 6 WC Pathology SC Pathology GA NB192 UT WOS:A1994NB19200009 PM 8119717 ER PT J AU SUCKOW, MA KEREN, DF BROWN, JE KEUSCH, GT AF SUCKOW, MA KEREN, DF BROWN, JE KEUSCH, GT TI STIMULATION OF GASTROINTESTINAL ANTIBODY TO SHIGA TOXIN BY OROGASTRIC IMMUNIZATION IN MICE SO IMMUNOLOGY AND CELL BIOLOGY LA English DT Article DE CHOLERA TOXIN; MICE; SHIGA; SHIGELLA DYSENTERIAE ID VASCULAR ENDOTHELIAL-CELLS; HEMOLYTIC-UREMIC SYNDROME; CHOLERA-TOXIN; SHIGELLA DIARRHEA; IMMUNE-RESPONSES; POLYMYXIN-B; SHIGELLA-DYSENTERIAE-1; PATHOGENESIS; PURIFICATION; ENTEROTOXIN AB Shiga toxin (ST) is a protein toxin of Shigella dysenteriae type 1, a causative agent of severe diarrhoea and dysentery. In this report we describe the gastrointestinal secretory antibody response of mice following orogastric immunization with ST. Gastrointestinal secretions were sampled by a gastrointestinal lavage technique weekly for 5 weeks after initial immunization. Assay of lavage samples by ELISA showed that mice vaccinated orogastrically with various doses of ST developed gastrointestinal antibody to ST in a dose-dependent manner. Serum anti-ST activity developed by 5 weeks after initial immunization. The ability of ST to act as a mucosal immune adjuvant was investigated by coadministration of ST and keyhole limpet haemocyanin. In contrast to cholera toxin, a potent adjuvant, ST did not demonstrate adjuvant activity. The mouse gastrointestinal lavage model could be useful for further analysis of the cellular basis of ST immunogenicity. C1 UNIV MICHIGAN,SCH MED,LAB ANIM MED UNIT,ANN ARBOR,MI. WARDE MED LAB,ANN ARBOR,MI. TUFTS UNIV NEW ENGLAND MED CTR,DEPT MED,DIV GEOG MED & INFECT DIS,BOSTON,MA 02111. TUFTS UNIV,SCH MED,BOSTON,MA 02111. ARMED FORCES RES INST MED SCI,BANGKOK 10400,THAILAND. RI Suckow, Mark/C-2696-2014; OI Suckow, Mark/0000-0001-7317-697X NR 36 TC 5 Z9 5 U1 0 U2 0 PU BLACKWELL SCIENCE PI CARLTON PA 54 UNIVERSITY ST, P O BOX 378, CARLTON VICTORIA 3053, AUSTRALIA SN 0818-9641 J9 IMMUNOL CELL BIOL JI Immunol. Cell Biol. PD FEB PY 1994 VL 72 IS 1 BP 69 EP 74 DI 10.1038/icb.1994.10 PG 6 WC Cell Biology; Immunology SC Cell Biology; Immunology GA MX799 UT WOS:A1994MX79900010 PM 8157288 ER PT J AU KRAKAUER, T AF KRAKAUER, T TI CELL-ADHESION MOLECULES ARE CO-RECEPTORS FOR STAPHYLOCOCCAL-ENTEROTOXIN B-INDUCED T-CELL ACTIVATION AND CYTOKINE PRODUCTION SO IMMUNOLOGY LETTERS LA English DT Article DE SUPERANTIGEN; SEB; COSTIMULATORY RECEPTOR; CYTOKINE ID TUMOR-NECROSIS-FACTOR; CD28; ICAM-1; ANTIBODY AB Enterotoxins produced by Staphylococcus aureus are potent mitogens for human T cells and cause lethal toxic shock. These superantigens bind to major histocompatibility complex class II on antigen-presenting cells outside the conventional peptide-binding groove and stimulate T cells expressing certain T-cell receptor V beta gene products. We investigated other cell-surface molecules on human peripheral blood mononuclear cells that can mediate staphylococcal enterotoxin B (SEB)-induced T-cell proliferation and cytokine production. SEE-induced proliferation of T cells was inhibited by monoclonal antibodies to CD2, CD11a, CD18, CD28, CD44, CD58 and ICAM-1. Anti-ICAM-1 also blocked the production of pro-inflammatory mediators, TNF alpha. and IFN gamma by SEB-stimulated T cells. These data suggest that the surface molecules, CD11a:CD18/ ICAM-1, CD2/CD58, CD28 and CD44, are all important co-receptors for T-cell activation by superantigens. Thus, like conventional antigens, multiple stimulatory signals from the interactions of these receptors are required for superantigen-induced immune responses. Reducing toxic mediators such as TNF alpha and IFN gamma by anti-ICAM antibodies in SEB-induced T-cell responses may be a useful therapeutic strategy to circumvent SEB toxicity and pathogenesis. RP KRAKAUER, T (reprint author), US ARMY,MED RES INST INFECT DIS,APPL RES DIV,BLDG 1425,FT DETRICK,MD 21702, USA. NR 28 TC 17 Z9 17 U1 0 U2 0 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0165-2478 J9 IMMUNOL LETT JI Immunol. Lett. PD FEB PY 1994 VL 39 IS 2 BP 121 EP 125 DI 10.1016/0165-2478(94)90096-5 PG 5 WC Immunology SC Immunology GA ND852 UT WOS:A1994ND85200003 PM 8013959 ER PT J AU MAHLE, JJ BUETTNER, LC FRIDAY, DK AF MAHLE, JJ BUETTNER, LC FRIDAY, DK TI MEASUREMENT AND CORRELATION OF THE ADSORPTION EQUILIBRIA OF REFRIGERANT VAPORS ON ACTIVATED CARBON SO INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH LA English DT Article ID HIGH-PRESSURE; EQUATION; METHANE; GASES AB Adsorption equilibrium data have been measured for four refrigerant vapors (R-113, R-11, R-318, and R-22) on BPL activated carbon at three temperatures over a wide range of partial pressures using an,automated isotherm apparatus. Special emphasis is placed on the design and operation of the apparatus to ensure the quality of these data. Isotherm data for each refrigerant vapor are analyzed for correct Henry's law behavior and correlated using three- and four-parameter functions with specified temperature dependencies. The functions employed in this study include (1) the Langmuir equation, (2) the Dubinin-Astakhov equation, (3) the virial equation, and (4) the modified Antoine equation. The Dubinin-Astakhov equation provides the best (or very comparable) fits, based on the variance, for R-113, R-11, and R-318. However, the Dubinin-Astakhov equation does not correctly describe the behavior of the R-22 data, resulting from its incorrect approach to Henry's law. Overall results show that, for adsorption of these refrigerants on BPL activated carbon, those correlations with exponents on the adsorbed-phase concentration terms greater than 1 generate the smallest variances. C1 GUILD ASSOCIATES INC,5022 CAMPBELL BLVD,BALTIMORE,MD 21236. USA,CTR DEV & ENGN,EDGEWOOD,ABERDEEN PROVING GROUND,MD 21010. NR 22 TC 17 Z9 17 U1 0 U2 3 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0888-5885 J9 IND ENG CHEM RES JI Ind. Eng. Chem. Res. PD FEB PY 1994 VL 33 IS 2 BP 346 EP 354 DI 10.1021/ie00026a027 PG 9 WC Engineering, Chemical SC Engineering GA MX339 UT WOS:A1994MX33900027 ER PT J AU CASTRIC, PA DEAL, CD AF CASTRIC, PA DEAL, CD TI DIFFERENTIATION OF PSEUDOMONAS-AERUGINOSA PILI BASED ON SEQUENCE AND B-CELL EPITOPE ANALYSES SO INFECTION AND IMMUNITY LA English DT Article ID BUCCAL EPITHELIAL-CELLS; MONOCLONAL-ANTIBODIES; NUCLEOTIDE-SEQUENCE; STRUCTURAL GENE; MORAXELLA-BOVIS; POLAR PILI; PAK PILIN; SUBUNIT; ADHERENCE; CLONING AB The nucleotide sequences of three previously undescribed Pseudomonas aeruginosa pilin structural genes are presented. Comparisons of deduced pilin primary structure and flanking DNA sequence allowed placement of these and six previously published sequences into one of two groups. Epitope mapping, using overlapping immobilized peptides representing the pilin primary structure, with antipilin monoclonal antibodies revealed several B-cell determinants grouped near the carboxyl terminus of P. aeruginosa 1244 pilin. One determinant was found to reside near the pilin constant region. These determinants were found associated with the pill of 31 of 95 P. aeruginosa clinical isolates. C1 WALTER REED ARMY INST RES,DEPT BACTERIAL DIS,WASHINGTON,DC 20307. RP CASTRIC, PA (reprint author), DUQUESNE UNIV,DEPT BIOL SCI,PITTSBURGH,PA 15282, USA. FU NIAID NIH HHS [AI24118] NR 36 TC 34 Z9 37 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0019-9567 J9 INFECT IMMUN JI Infect. Immun. PD FEB PY 1994 VL 62 IS 2 BP 371 EP 376 PG 6 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA MR841 UT WOS:A1994MR84100006 PM 7507890 ER PT J AU HARTMAN, AB VANDEVERG, L COLLINS, HH TANG, DB BENDIUK, NO TAYLOR, DN POWELL, CJ AF HARTMAN, AB VANDEVERG, L COLLINS, HH TANG, DB BENDIUK, NO TAYLOR, DN POWELL, CJ TI LOCAL IMMUNE-RESPONSE AND PROTECTION IN THE GUINEA-PIG KERATOCONJUNCTIVITIS MODEL-FOLLOWING IMMUNIZATION WITH SHIGELLA VACCINES SO INFECTION AND IMMUNITY LA English DT Article ID ANTIBODY-RESPONSES; SECRETORY IMMUNOGLOBULIN; CHOLERA VACCINATION; SERUM ANTIBODIES; NATURAL IMMUNITY; FLEXNERI; TOXIN; INFECTION; ANTIGEN; SONNEI AB This study used the guinea pig keratoconjunctivitis model to examine the importance of route of administration (mucosal versus parenteral), frequency and timing of immunization (primary versus boosting immunization), and form of antigen given (live attenuated vaccine strain versus O-antigen-protein conjugate) on the production of protective immunity against Shigella infection. Since local immune response to the lipopolysaccharide (LPS) O-antigen of Shigella spp. is thought to be important for protection against disease, O-antigen-specific antibody-secreting cells (ASC) in the spleen and regional lymph nodes of immunized animals were measured by using an ELISPOT assay. Results indicated that protective efficacy was associated with a strong O-antigen-specific ASC response, particularly in the superficial ventral cervical lymph nodes draining the conjunctivae. In naive animals, a strong ASC response in the cervical lymph nodes and protection against challenge were detected only in animals that received a mucosal immunization. Protection in these animals was increased by a boosting mucosal immunization. While parenteral immunization alone with an O-antigen-protein conjugate vaccine did not protect naive animals against challenge, a combined parenteral-mucosal regimen elicited enhanced protection without the addition of a boosting immunization. Although O-antigen-specific serum immunoglobulin A titers were significantly higher in animals receiving a mucosal immunization, there was no apparent correlation between levels of serum antibody and protection against disease. C1 WALTER REED ARMY INST RES,DEPT BIOL RES,WASHINGTON,DC 20307. UNIVAX BIOL INC,ROCKVILLE,MD 20852. WALTER REED ARMY INST RES,DEPT BIOSTAT & MATH,WASHINGTON,DC 20307. RP HARTMAN, AB (reprint author), WALTER REED ARMY MED CTR,WALTER REED ARMY INST RES,DEPT ENTER INFECT,BLDG 40,WASHINGTON,DC 20307, USA. NR 42 TC 20 Z9 24 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0019-9567 J9 INFECT IMMUN JI Infect. Immun. PD FEB PY 1994 VL 62 IS 2 BP 412 EP 420 PG 9 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA MR841 UT WOS:A1994MR84100012 PM 7507892 ER PT J AU RABIN, J AF RABIN, J TI OPTICAL DEFOCUS - DIFFERENTIAL-EFFECTS ON SIZE AND CONTRAST LETTER RECOGNITION THRESHOLDS SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Article DE VISUAL ACUITY; CONTRAST SENSITIVITY; DEFOCUS; BLUR; VISION TESTING ID DIOPTRIC BLUR; SENSITIVITY; ACUITY; DESIGN AB Purpose. To determine if optical defocus produces a greater reduction in Visual acuity or small-letter contrast sensitivity. Methods. Letter charts were used to measure visual acuity and small-letter contrast sensitivity (20/25 Snellen equivalent) as a function of optical defocus. Letter size (acuity) and contrast (contrast sensitivity) were varied in equal logarithmic steps to make the task the same for the two types of measurement. Results. Both visual acuity and contrast sensitivity declined with optical defocus, but the effect was far greater in the contrast domain. However, measurement variability also was greater for contrast sensitivity. After correction for this variability, measurement in the contrast domain still proved to be a more sensitive (1.75X) index of optical defocus. Conclusions. Small-letter contrast sensitivity is a powerful technique for detecting subtle amounts of optical defocus. This adjunctive approach may be useful when there are small changes in resolution that are not detected by standard measures of visual acuity. Potential applications include evaluating the course of vision in refractive surgery, classification of cataracts, detection of corneal or macular edema, and detection of visual loss in the aging eye. Evaluation of candidates for occupations requiring unique visual abilities also may be enhanced by measuring resolution in the contrast domain. RP RABIN, J (reprint author), USA,AEROMED RES LAB,DIV AIRCREW HLTH & PERFORMANCE,FT RUCKER,AL 36362, USA. NR 9 TC 26 Z9 27 U1 2 U2 2 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0146-0404 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD FEB PY 1994 VL 35 IS 2 BP 646 EP 648 PG 3 WC Ophthalmology SC Ophthalmology GA MY957 UT WOS:A1994MY95700041 PM 8113015 ER PT J AU COWAN, DN BRUNDAGE, JF POMERANTZ, RS AF COWAN, DN BRUNDAGE, JF POMERANTZ, RS TI HIV-INFECTION AMONG WOMEN IN THE ARMY RESERVE COMPONENTS SO JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY LA English DT Article DE HIV; PREVALENCE; INCIDENCE DENSITY; WOMEN; EPIDEMIOLOGY; DEMOGRAPHY ID IMMUNODEFICIENCY-VIRUS-INFECTION; UNITED-STATES-ARMY; YOUNG-ADULTS; PREVALENCE; MEMBERS; SEROCONVERSION; SEROPREVALENCE; CORPS AB There is little information regarding the extent of HIV infection among women. Since late 1985, members of the Army Reserve Components have been routinely tested for HIV, providing an opportunity to measure directly the prevalence and incidence density of infection in a military-associated population with limited military contact. We evaluated the prevalence among 122,195 women, and directly measured the incidence density among 96,001 women followed for 247,872 person-years. The overall prevalence was 0.65 (per 1000), and the incidence density was 0.12 (per 1000 person years follow-up). Several demographically defined groups, including minority women, had elevated levels of infection. The incidence densities of infection between early and late in the testing program were compared, and no evidence of acceleration or deceleration was observed. C1 SRA TECHNOL INC,ALEXANDRIA,VA. WALTER REED ARMY INST RES,DIV PREVENT MED,WASHINGTON,DC. NR 21 TC 7 Z9 7 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 1077-9450 J9 J ACQ IMMUN DEF SYND JI J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. PD FEB PY 1994 VL 7 IS 2 BP 171 EP 176 PG 6 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA MW114 UT WOS:A1994MW11400013 PM 8301528 ER PT J AU TAKAGI, S AF TAKAGI, S TI THERMODYNAMICS OF SOIL-MOISTURE WITH ADSORPTION CONSIDERED SO JOURNAL OF COLLOID AND INTERFACE SCIENCE LA English DT Note C1 COLD REG RES & ENGN LAB,HANOVER,NH 03755. NR 6 TC 0 Z9 0 U1 1 U2 1 PU ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 SN 0021-9797 J9 J COLLOID INTERF SCI JI J. Colloid Interface Sci. PD FEB PY 1994 VL 162 IS 2 BP 510 EP 511 DI 10.1006/jcis.1994.1068 PG 2 WC Chemistry, Physical SC Chemistry GA MU063 UT WOS:A1994MU06300030 ER PT J AU ELSTON, DM AF ELSTON, DM TI PAPILLOMAVIRUS-INFECTED EPIDERMOID CYSTS - REPLY SO JOURNAL OF CUTANEOUS PATHOLOGY LA English DT Letter RP ELSTON, DM (reprint author), BROOKE ARMY MED CTR,MED CORPS,FT SAM HOUSTON,TX 78234, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MUNKSGAARD INT PUBL LTD PI COPENHAGEN PA 35 NORRE SOGADE, PO BOX 2148, DK-1016 COPENHAGEN, DENMARK SN 0303-6987 J9 J CUTAN PATHOL JI J. Cutan. Pathol. PD FEB PY 1994 VL 21 IS 1 BP 94 EP 94 DI 10.1111/j.1600-0560.1994.tb00700.x PG 1 WC Dermatology; Pathology SC Dermatology; Pathology GA NA687 UT WOS:A1994NA68700018 ER PT J AU GALVAN, DA CIARLONE, AE PASHLEY, DH KULILD, JC PRIMACK, PD SIMPSON, MD AF GALVAN, DA CIARLONE, AE PASHLEY, DH KULILD, JC PRIMACK, PD SIMPSON, MD TI EFFECT OF SMEAR LAYER REMOVAL ON THE DIFFUSION PERMEABILITY OF HUMAN ROOTS SO JOURNAL OF ENDODONTICS LA English DT Article ID HUMAN DENTINAL TUBULES; ENDODONTIC PROCEDURES; THICKNESS AB Ten human maxillary incisors, extracted because of periodontal disease or nonrestorable caries, were obtained and instrumented to a size #70 K-Flex file at the working length using a standard stepback technique. Tritiated water (H2O)-H-3 was placed in the root canals and allowed to diffuse to the external surface of the roots until it reached a constant rate. The smear layer in each of the experimental roots was then removed using 0.5 M EDTA followed by 5.25% sodium hypochlorite (NaOCl). The constant rate diffusion of H2O was remeasured. The roots were then stored in deionized H2O for 2 months and the constant rate diffusion of (H2O)-H-3 was remeasured. A statistically significant difference was noted between all three groups. A decrease in the diffusion permeability of the root to (H2O)-H-3 was noted immediately after smear layer removal and the highest permeability was recorded after storage in the deionized water for 2 months. C1 USA DENT ACT,FT LEONARD WOOD,MO. MED COLL GEORGIA,SCH DENT,DEPT ORAL BIOL PHARMACOL,AUGUSTA,GA 30912. USA DENT ACT,USA POSTGRAD DENT SCH,FT GORDON,GA 30905. NR 14 TC 20 Z9 20 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0099-2399 J9 J ENDODONT JI J. Endod. PD FEB PY 1994 VL 20 IS 2 BP 83 EP 86 DI 10.1016/S0099-2399(06)81187-8 PG 4 WC Dentistry, Oral Surgery & Medicine SC Dentistry, Oral Surgery & Medicine GA NA612 UT WOS:A1994NA61200007 PM 8006571 ER PT J AU STARK, TD EBELING, RM VETTEL, JJ AF STARK, TD EBELING, RM VETTEL, JJ TI HYPERBOLIC STRESS-STRAIN PARAMETERS FOR SILTS SO JOURNAL OF GEOTECHNICAL ENGINEERING-ASCE LA English DT Article ID SOILS AB The hyperbolic stress-strain model has been shown to be valid for modeling the nonlinear stress-strain behavior of soils prior to failure in soil-structure interaction analyses. However, guidelines for selecting hyperbolic stress-strain parameters for silts have not been published to date. To fill this need, a series of isotropically consolidated-drained and consolidated-undrained triaxial tests were performed on freshly deposited, normally consolidated silts and clayey silts to provide guidance for selecting hyperbolic parameters for the-se materials. The effect of clay mineral content and dry unit weight on the hyperbolic parameters was investigated by reconstituting specimens at clay mineral contents of 0, 10, 20, 30, and 50% by dry weight and at standard Proctor relative compactions of 85, 90, 95, and 100%. At low clay mineral contents, the normally consolidated silt exhibited dilative shear behavior while a contractive behavior was observed at high clay mineral contents. The transition from dilative to contractive shear behavior is controlled by clay mineralogy. Due to the dilative behavior of the normally consolidated silt mixtures, failure criteria of maximum deviator stress and maximum pore-water pressure were used to obtain the Mohr-Coulomb, shear strength parameters from the drained and undrained triaxial tests. C1 USA,ENGINEER WATERWAYS EXPT STN,VICKSBURG,MS 39180. M&T AGRA INC,SAN DIEGO,CA 92127. RP STARK, TD (reprint author), UNIV ILLINOIS,MC-250,205 N MATHEWS AVE,URBANA,IL 61801, USA. NR 27 TC 10 Z9 11 U1 0 U2 3 PU ASCE-AMER SOC CIVIL ENGINEERS PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2398 SN 0733-9410 J9 J GEOTECH ENG-ASCE JI J. Geotech. Eng.-ASCE PD FEB PY 1994 VL 120 IS 2 BP 420 EP 441 DI 10.1061/(ASCE)0733-9410(1994)120:2(420) PG 22 WC Engineering, Civil; Geosciences, Multidisciplinary SC Engineering; Geology GA MT828 UT WOS:A1994MT82800010 ER PT J AU ABT, SR HAMILTON, GB WATSON, CC SMITH, J AF ABT, SR HAMILTON, GB WATSON, CC SMITH, J TI RIPRAP SIZING FOR MODIFIED ARS-TYPE BASIN SO JOURNAL OF HYDRAULIC ENGINEERING-ASCE LA English DT Note C1 CH2M HILL INC,DENVER,CO 80522. USA,CORPS ENGINEERS,VICKSBURG,MS 39181. RP ABT, SR (reprint author), COLORADO STATE UNIV,ENGN RES CTR,DEPT CIVIL ENGN,FOOTHILLS CAMPUS,FT COLLINS,CO 80523, USA. NR 4 TC 0 Z9 0 U1 0 U2 0 PU ASCE-AMER SOC CIVIL ENGINEERS PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2398 SN 0733-9429 J9 J HYDRAUL ENG-ASCE JI J. Hydraul. Eng.-ASCE PD FEB PY 1994 VL 120 IS 2 BP 260 EP 267 DI 10.1061/(ASCE)0733-9429(1994)120:2(260) PG 8 WC Engineering, Civil; Engineering, Mechanical; Water Resources SC Engineering; Water Resources GA MT458 UT WOS:A1994MT45800010 ER PT J AU NATH, J POWLEDGE, A WRIGHT, DG AF NATH, J POWLEDGE, A WRIGHT, DG TI INVOLVEMENT OF A BOTULINUM TOXIN-SENSITIVE 22-KDA G-PROTEIN IN STIMULATED EXOCYTOSIS OF HUMAN NEUTROPHILS SO JOURNAL OF IMMUNOLOGY LA English DT Article ID GTP-BINDING PROTEIN; ADP-RIBOSYLATION; MAST-CELLS; GUANINE-NUCLEOTIDES; SYNAPTIC VESICLES; SECRETION; YEAST; MEMBRANE; CALCIUM; RIBOSYLTRANSFERASE AB Studies of human peripheral blood neutrophils (PMNs) demonstrated that botulinum neurotoxin D (BT-D) ADP-ribosylates a 22-kDa PMN G protein (G22k) and inhibits the exocytosis of both specific and azurophilic granules stimulated by FMLP. Furthermore, this inhibition of PMN exocytosis by, BT-D was found to be correlated with the degree of irreversible ADP-ribosylation of G22k by BT-D and to require modification of at least 85% of PMN G22k before significant inhibition of secretion is observed. Although both pertussis toxin and BT-D inhibited exocytosis in FMLP-stimulated PMNs, the inhibitory effects of the two toxins were found to be additive. Pertussis toxin and BT-D also inhibited Ca2+/GTP/GTPgammaS-induced secretion in digitonin-permeabilized PMNs, but there were distinct differences between the inhibitory effects of the two toxins. In contrast to BT-D, the exotoxin botulinum C3 was found to ADP-ribosylate primarily a 24- to 25-kDa PMN protein, and it was not found to inhibit Ca2+- and GTP-induced secretion in permeabilized PMNs. Ultrastructural studies of BT-D-treated PMNs showed an accumulation of distinct membrane-bound organelles in the periphery of the cells after FMLP stimulation, suggestive of a toxin-induced block in organelle-plasma membrane fusion. Taken together, these findings indicate that BT-D-sensitive G22k has a functional role in stimulated exocytosis of PMNs. RP NATH, J (reprint author), WALTER REED ARMY INST RES,DEPT HEMATOL,DIV MED,WASHINGTON,DC 20307, USA. NR 52 TC 10 Z9 10 U1 0 U2 1 PU AMER ASSOC IMMUNOLOGISTS PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 0022-1767 J9 J IMMUNOL JI J. Immunol. PD FEB 1 PY 1994 VL 152 IS 3 BP 1370 EP 1379 PG 10 WC Immunology SC Immunology GA MV630 UT WOS:A1994MV63000047 PM 8301138 ER PT J AU SATTABONGKOT, J SUWANABUN, N RONGNOPARUT, P WIRTZ, RA KAIN, KC ROSENBERG, R AF SATTABONGKOT, J SUWANABUN, N RONGNOPARUT, P WIRTZ, RA KAIN, KC ROSENBERG, R TI COMPARATIVE TEST OF DNA PROBES FOR DETECTION OF PLASMODIUM-VIVAX CIRCUMSPOROZOITE PROTEIN POLYMORPHS VK-247 AND VK-210 SO JOURNAL OF INFECTIOUS DISEASES LA English DT Note ID MONOCLONAL-ANTIBODIES; ELISA DEVELOPMENT; SPOROZOITES AB Oligonucleotide probes specific to the characteristic repeat sequences of two alleles of the circumsporozoite protein gene of Plasmodium vivax (VK 210 and VK 247) were selected, synthesized, and tested on matched blood and sporozoite DNA amplified by polymerase chain reaction from 182 cases naturally acquired in Thailand. Probe results were compared to those of circumsporozoite phenotype-specific ELISAs used to evaluate sporozoites from the same cases. There was a 96% agreement between probe results for blood and for sporozoites. Although there was also a nearly complete agreement between probe and ELISA results for cases producing only VK 210 or VK 247 sporozoites, the probes detected 45% more mixed infections than did the ELISAs when used to test specimens from western and southern Thailand; there was no discrepancy when mixed cases from Cambodia were tested. Examination of Southern blots from ambiguous mixed cases demonstrated the presence of both genes, suggesting suppression of VK 247 in some mixed cases to numbers below those detectable by the ELISA. C1 WALTER REED ARMY INST RES,DEPT ENTOMOL,WASHINGTON,DC 20307. USA,MED COMPONENT,DEPT ENTOMOL,BANGKOK,THAILAND. TORONTO HOSP,TROP DIS UNIT,TORONTO,ON,CANADA. NR 12 TC 7 Z9 7 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD FEB PY 1994 VL 169 IS 2 BP 464 EP 466 PG 3 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA MV829 UT WOS:A1994MV82900040 PM 8106786 ER PT J AU SHOENBERGER, JE AF SHOENBERGER, JE TI PERFORMANCE OF FUEL-RESISTANT SEALERS FOR ASPHALT CONCRETE PAVEMENTS SO JOURNAL OF MATERIALS IN CIVIL ENGINEERING LA English DT Article AB In many pavement applications, asphalt concrete is exposed to damage from fuel spills or drippage. A fuel-resistant sealer (FRS) is often required to protect the asphalt concrete pavement from possible damage. Coal-tar emulsion mixtures with an aggregate added to provide for skid resistance is commonly used to protect the pavements. These mixtures or sealers often contain additive materials designed to improve sealer performance. The development of fuel-resistant sealers and various additives and their effects on the performance of the sealers are discussed. Also discussed are procedures normally used for mixing and applying the sealers, materials, and proportioning and construction practices that can affect the held performance of these sealers. Recent research financed by several government agencies has sought improved methods for specifying and testing coal-tar sealer mixtures. The methods currently used for specifying and testing these mixtures and the needs of user agencies are discussed. RP SHOENBERGER, JE (reprint author), USA,ENGINEER WATERWAYS EXPT STN,CEWES GP Q,3909 HALLS FERRY RD,VICKSBURG,MS 39180, USA. NR 16 TC 2 Z9 2 U1 0 U2 1 PU ASCE-AMER SOC CIVIL ENG PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2398 SN 0899-1561 J9 J MATER CIVIL ENG JI J. Mater. Civ. Eng. PD FEB PY 1994 VL 6 IS 1 BP 137 EP 149 DI 10.1061/(ASCE)0899-1561(1994)6:1(137) PG 13 WC Construction & Building Technology; Engineering, Civil; Materials Science, Multidisciplinary SC Construction & Building Technology; Engineering; Materials Science GA QA951 UT WOS:A1994QA95100011 ER PT J AU GARTNER, S LIU, YL POLONIS, V LEWIS, MG ELKINS, WR HUNTER, EA MIAO, J CORTS, KJ EDDY, GA AF GARTNER, S LIU, YL POLONIS, V LEWIS, MG ELKINS, WR HUNTER, EA MIAO, J CORTS, KJ EDDY, GA TI ADAPTATION OF HIV-1 TO PIGTAILED MACAQUES SO JOURNAL OF MEDICAL PRIMATOLOGY LA English DT Article; Proceedings Paper CT 11th Annual Meeting on Nonhuman Primate Models for AIDS VI CY SEP 19-22, 1993 CL UNIV WISCONSIN MADISON, WISCONSIN REG PRIMATE RES CTR, MADISON, WI HO UNIV WISCONSIN MADISON, WISCONSIN REG PRIMATE RES CTR DE HIV; INFECTION; MONKEYS ID HUMAN-IMMUNODEFICIENCY-VIRUS; HTLV-III; CYNOMOLGUS MACAQUES; MACACA-FASCICULARIS; T-CELL; INFECTION; MONKEYS; RHESUS; RETROVIRUSES; LYMPHOCYTES AB In vitro infectivity experiments were performed to assess the susceptibility of cells from various monkey species to HIV-1. T lymphocytes from pigtailed macaques, but not those from rhesus or cynomolgus monkeys, were susceptible to infection, but virus expression was limited. The majority of HIV-1 isolates were unable to productively infect pigtailed macaque cells. Inoculation of autologous, HIV-1 expressing cells led to establishment of persistent infection in pigtailed macaques as evidenced by recovery of infectious virus and development of virus-specific antibody responses. C1 WALTER REED ARMY INST RES,DEPT RETROVIRAL RES,DIV RETROVIROL,ROCKVILLE,MD. NIAID,BETHESDA,MD 20892. RP GARTNER, S (reprint author), HENRY M JACKSON FDN,RES LAB,1500 E GUDE DR,ROCKVILLE,MD 20850, USA. NR 27 TC 15 Z9 16 U1 0 U2 0 PU MUNKSGAARD INT PUBL LTD PI COPENHAGEN PA 35 NORRE SOGADE, PO BOX 2148, DK-1016 COPENHAGEN, DENMARK SN 0047-2565 J9 J MED PRIMATOL JI J. Med. Primatol. PD FEB-MAY PY 1994 VL 23 IS 2-3 BP 155 EP 163 PG 9 WC Veterinary Sciences; Zoology SC Veterinary Sciences; Zoology GA NX987 UT WOS:A1994NX98700015 PM 7966231 ER PT J AU SOZUER, HS DOWLING, JP AF SOZUER, HS DOWLING, JP TI PHOTONIC BAND CALCULATIONS FOR WOODPILE STRUCTURES SO JOURNAL OF MODERN OPTICS LA English DT Article ID ATOMS AB Photonic band structure has been computed for 'woodpile' structures having the periodicity of the simple tetragonal lattice. Bandgaps have been found. Further research directions are explored. C1 USA,MISSILE COMMAND,WEAP SCI DIRECTORATE,AMSMI,RD,WS,ST,CTR RES DEV & ENGN,REDSTONE ARSENAL,AL 35898. RP SOZUER, HS (reprint author), RENSSELAER POLYTECH INST,DEPT PHYS,TROY,NY 12180, USA. RI Sozuer, Huseyin Sami/H-9552-2012; DOWLING, JONATHAN/L-2749-2013 NR 16 TC 153 Z9 151 U1 1 U2 6 PU TAYLOR & FRANCIS LTD PI LONDON PA ONE GUNDPOWDER SQUARE, LONDON, ENGLAND EC4A 3DE SN 0950-0340 J9 J MOD OPTIC JI J. Mod. Opt. PD FEB PY 1994 VL 41 IS 2 BP 231 EP 239 DI 10.1080/09500349414550291 PG 9 WC Optics SC Optics GA NA271 UT WOS:A1994NA27100005 ER PT J AU DOWLING, JP BOWDEN, CM AF DOWLING, JP BOWDEN, CM TI ANOMALOUS INDEX OF REFRACTION IN PHOTONIC BANDGAP MATERIALS SO JOURNAL OF MODERN OPTICS LA English DT Article ID COHERENCE; EMISSION; LIGHT; MEDIA AB Near the gap in a photonic bandgap material the effective index of ;refraction can become less than unity and in fact can approach zero at the band edge itself-leading to ultra-refractive optical effects. We illustrate this effect quantitatively in a simple one-dimensional Kronig-Penney model of a three-dimensional bandgap structure. As a complement to index-enhancing schemes involving lasing without inversion, ultra-refractive optics with photonic band materials has many applications, including laser accelerators and lenses of ultra-short focal lengths. RP DOWLING, JP (reprint author), USA,MISSILE COMMAND,WEAP SCI DIRECTORATE,AMSMI,RD,WS,ST,CTR DEV & ENGN,REDSTONE ARSENAL,AL 35898, USA. RI DOWLING, JONATHAN/L-2749-2013 NR 25 TC 128 Z9 133 U1 0 U2 11 PU TAYLOR & FRANCIS LTD PI LONDON PA ONE GUNDPOWDER SQUARE, LONDON, ENGLAND EC4A 3DE SN 0950-0340 J9 J MOD OPTIC JI J. Mod. Opt. PD FEB PY 1994 VL 41 IS 2 BP 345 EP 351 DI 10.1080/09500349414550371 PG 7 WC Optics SC Optics GA NA271 UT WOS:A1994NA27100013 ER PT J AU FUSZARD, B GREEN, E KUJALA, E TALLEY, B AF FUSZARD, B GREEN, E KUJALA, E TALLEY, B TI RURAL MAGNET HOSPITALS OF EXCELLENCE .2. SO JOURNAL OF NURSING ADMINISTRATION LA English DT Article ID NURSES AB Although almost half of the hospitals in the United States are rural and small, they often are not seen as leaders in innovation. However, many practices now being adopted by large hospitals have been used in rural hospitals for many years. To understand excellence in rural hospitals, the authors present a study of rural hospitals of excellence, using procedures from the 1982 Magnet Hospital Study. Part 1 was reported in the January issue of JONA. C1 WOODWARD WHITE INC,AIKEN,SC. DWIGHT D EISENHOWER ARMY MED CTR,FT GORDON,GA 30905. GEORGIA SO UNIV,ARMSTRONG STATE COLL,SAVANNAH,GA. RP FUSZARD, B (reprint author), MED COLL GEORGIA,AUGUSTA,GA 30912, USA. NR 11 TC 0 Z9 1 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0002-0443 J9 J NURS ADMIN JI J. Nurs. Adm. PD FEB PY 1994 VL 24 IS 2 BP 35 EP 41 DI 10.1097/00005110-199402000-00011 PG 7 WC Nursing SC Nursing GA MW777 UT WOS:A1994MW77700012 PM 8301393 ER PT J AU BERRY, DD PRAMANIK, AK PHILIPS, JB BUCHTER, DS KANAREK, KS EASA, D KOPELMAN, AE EDWARDS, K LONG, W AVILA, E BEAUMONT, D COOK, L DHANIREDDY, R JARRETT, R PURI, A ROSENBERG, A VOLBERG, F AF BERRY, DD PRAMANIK, AK PHILIPS, JB BUCHTER, DS KANAREK, KS EASA, D KOPELMAN, AE EDWARDS, K LONG, W AVILA, E BEAUMONT, D COOK, L DHANIREDDY, R JARRETT, R PURI, A ROSENBERG, A VOLBERG, F TI COMPARISON OF THE EFFECT OF 3 DOSES OF A SYNTHETIC SURFACTANT ON THE ALVEOLAR-ARTERIAL OXYGEN GRADIENT IN INFANTS WEIGHING GREATER-THAN-OR-EQUAL-TO-1250 GRAMS WITH RESPIRATORY-DISTRESS SYNDROME SO JOURNAL OF PEDIATRICS LA English DT Article ID RANDOMIZED CONTROLLED TRIAL; HYALINE-MEMBRANE DISEASE; PLACEBO-CONTROLLED TRIAL; 30 WEEKS GESTATION; BOVINE SURFACTANT; REPLACEMENT THERAPY; MULTICENTER TRIAL; PREMATURE-INFANTS; MORTALITY-RATE; SINGLE AB The effect of a 50% increment or decrement in the recommended 5 ml/kg dose of a commercially available surfactant (Exosurf Neonatal) on the alveolar-arterial oxygen gradient was investigated in a multicenter, double-blind, placebo-controlled rescue trial conducted at 15 hospitals in the United States. Two doses of three different volumes (2.5, 5.0, and 7.5 ml/kg) were compared with two 5.0 ml/kg doses of air in 281 infants weighing greater than or equal to 1250 gm who had respiratory distress syndrome requiring mechanical ventilation and an arterial/alveolar oxygen ratio < 0.22. The first dose was given between 2 and 26 hours of age, and the second dose was given 12 hours later to all infants who still required mechanical ventilation. Infants were stratified at entry by gender and the magnitude of the arterial/alveolar oxygen ratio. The air placebo arm of the study was terminated early when reductions in mortality rates were proved in another rescue trial of this surfactant in infants with the same birth weights. For the first 48 hours, administration of a 2.5 ml/kg dose of surfactant provided less improvement in the alveolar-arterial oxygen gradient than doses of 5.0 and 7.5 ml/kg, which were equivalent. Similar results were observed in mean airway pressure (p < 0.05). There were no significant differences among the three dosage groups in mortality rate, air leak, bronchopulmonary dysplasia, and other complications of prematurity. There were no pulmonary hemorrhages in any group. Reflux of surfactant occurred more frequently in the 5.0 and 7.5 ml/kg groups. These results indicate that more sustained improvements in oxygenation are provided, with equal safety, by the standard two 5.0 ml/kg rescue doses of this surfactant than by the 2.5 ml/kg dose. No further benefit is gained from two larger doses given 12 hours apart. C1 BURROUGHS WELLCOME CO, DEPT CLIN STAT, RES TRIANGLE PK, NC USA. UNIV N CAROLINA, DEPT PEDIAT, CHAPEL HILL, NC USA. BURROUGHS WELLCOME CO, DIV CLIN RES, RES TRIANGLE PK, NC USA. LOUISIANA STATE UNIV, MED CTR, DEPT PEDIAT, SHREVEPORT, LA USA. UNIV ALABAMA, MED CTR, DEPT PEDIAT, BIRMINGHAM, AL 35294 USA. EMORY UNIV, SCH MED, DEPT PEDIAT, ATLANTA, GA USA. UNIV S FLORIDA, DEPT PEDIAT, TAMPA, FL USA. UNIV HAWAII, DEPT PEDIAT, HONOLULU, HI USA. E CAROLINA UNIV, DEPT PEDIAT, GREENVILLE, NC USA. ALASKA NEONATAL ASSOC, ANCHORAGE, AK USA. BUTTERWORTH HOSP, GRAND RAPIDS, MI USA. UNIV LOUISVILLE, LOUISVILLE, KY USA. GEORGETOWN UNIV HOSP, WASHINGTON, DC USA. KAPIOLANI MED CTR WOMEN & CHILDREN, HONOLULU, HI USA. TRIPLER ARMY MED CTR, HONOLULU, HI USA. CEDARS SINAI MED CTR, LOS ANGELES, CA USA. UNIV COLORADO, HLTH SCI CTR, DENVER, CO USA. RP BERRY, DD (reprint author), WAKE FOREST UNIV, BOWMAN GRAY SCH MED, DEPT PEDIAT, MED CTR BLVD, WINSTON SALEM, NC 27157 USA. NR 27 TC 17 Z9 17 U1 0 U2 0 PU MOSBY-ELSEVIER PI NEW YORK PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA SN 0022-3476 EI 1097-6833 J9 J PEDIATR-US JI J. Pediatr. PD FEB PY 1994 VL 124 IS 2 BP 294 EP 301 DI 10.1016/S0022-3476(94)70323-X PG 8 WC Pediatrics SC Pediatrics GA MV834 UT WOS:A1994MV83400024 PM 8301442 ER PT J AU TORTELLA, FC ROBLES, L WITKIN, JM NEWMAN, AH AF TORTELLA, FC ROBLES, L WITKIN, JM NEWMAN, AH TI NOVEL ANTICONVULSANT ANALOGS OF DEXTROMETHORPHAN - IMPROVED EFFICACY, POTENCY, DURATION AND SIDE-EFFECT PROFILE SO JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS LA English DT Article ID METHYL-D-ASPARTATE; GUINEA-PIG BRAIN; PHENCYCLIDINE-LIKE DRUGS; BINDING-SITES; PHARMACOLOGICAL FACTORS; LABORATORY EVALUATION; INDUCED CONVULSIONS; RECEPTOR LIGANDS; RAT-BRAIN; DEXTRORPHAN AB The anticonvulsant and neuroprotective activity of dextromethorphan (DM, [+]-3-methyl-17-methylmorphinan) may be, in part, due to its metabolism to the phencyclidine hydrochloride-like compound dextrorphan (DX). We evaluated the anticonvulsant activity and neurological impairing effects in rats of three novel analogs of DM which, based upon their position-3 substituents, would either not be expected to be metabolized to DX or might do so at a reduced rate. The DM analogs were determined to be more potent and more efficacious than DM against maximal electroshock convulsions; two of the analogs, namely [(+)-3-ethoxy-17- methylmorphinan] and [(+)-3-(2-propoxy)-17-methylmorphinan], were equipotent to DX. [(+)3-Ethoxy-17-methylmorphinan] and L[(+)-3-(2-propoxy)-17-methylmorphinan) exhibited a duration of action (1-2 hr) slightly longer than DX (0.5-1 hr) and similar to DM (2-4 hr). The anticonvulsant effect of [(+)3-amino-17- methylmorphinan] persisted 4-6 hr. Against flurothyl convulsions DM was proconvulsant, DX was anticonvulsant and the DM analogs were inactive. In contrast, N-methyl-D-aspartate convulsions were antagonized by i.c.v. pretreatment with DM and the DM analogs, albeit with a potency approximately 10 times less than that of DX. Results of rotarod performance testing further distinguished the analogs from DM, DX or the anticonvulsant drug diazepam. No behavioral impairment was observed at the highest doses tested of each of the DM analogs, resulting in protective indices (i.e., rotarod TD50/maximal electroshock anticonvulsant ED(50)) greatly exceeding DM, DX or clinical anticonvulsant drugs. The results of this study establish these 3-substituted DM analogs as novel anticonvulsants exhibiting improved potency, efficacy, duration and side-effect profiles. C1 NIDA,ADDICT RES CTR,PSYCHOBIOL SECT,DRUG DEV GRP,BALTIMORE,MD 21224. RP TORTELLA, FC (reprint author), WALTER REED ARMY INST RES,DEPT MED NEUROSCI,NEUROPHARMACOL BRANCH,WASHINGTON,DC 20307, USA. NR 53 TC 29 Z9 29 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0022-3565 J9 J PHARMACOL EXP THER JI J. Pharmacol. Exp. Ther. PD FEB PY 1994 VL 268 IS 2 BP 727 EP 733 PG 7 WC Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA MY586 UT WOS:A1994MY58600028 PM 8113984 ER PT J AU LI, YL WHITE, MJ FRANKE, SJ AF LI, YL WHITE, MJ FRANKE, SJ TI NEW FAST FIELD PROGRAMS FOR ANISOTROPIC SOUND-PROPAGATION THROUGH AN ATMOSPHERE WITH A WIND VELOCITY PROFILE SO JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA LA English DT Article ID 2-WAY WAVE-EQUATION; TEMPERATURE-GRADIENTS; TRANSFORM; TUTORIAL; FFP AB Two new fast field programs (FFP) have been developed for numerical computation of anisotropic sound propagation through an atmosphere with a wind velocity profile. The first new FFP can be used to compute the near-field and far-field sound pressure. The numerical implementation of the FFP is based on an integration algorithm using a two-dimensional fast Fourier transform with iterative refinement. For studying problems of long-range propagation, a novel far-field expression for sound pressure is derived. The second new FFP is based on this far-field approximation. If the magnitude of wind speed is not very large; this new far-field expression shows that the component of wind perpendicular to the direction of propagation has no effect on long-range propagation. Numerical results from both new fast field programs demonstrate that the effective sound-speed model used in the conventional FFP's is still valid for propagation within a certain range. However, the agreement between methods becomes worse at longer horizontal distance. These numerical results also show that the effective sound-speed model will produce phase errors for higher angle modes, which is most apparent when a single mode dominates the solution. When many modes are present, the envelopes of the curves match, but the details do not. C1 USA,CONSTRUCT ENGN RES LAB,CHAMPAIGN,IL 61826. RP LI, YL (reprint author), UNIV ILLINOIS,DEPT ELECT & COMP ENGN,WAVE PROPAGAT LAB,1308 W MAIN ST,URBANA,IL 61801, USA. RI White, Michael/B-3612-2009 OI White, Michael/0000-0001-8450-9135 NR 16 TC 17 Z9 18 U1 1 U2 1 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0001-4966 J9 J ACOUST SOC AM JI J. Acoust. Soc. Am. PD FEB PY 1994 VL 95 IS 2 BP 718 EP 726 DI 10.1121/1.408431 PG 9 WC Acoustics; Audiology & Speech-Language Pathology SC Acoustics; Audiology & Speech-Language Pathology GA MW284 UT WOS:A1994MW28400013 ER PT J AU MOODY, JM RUBAL, BJ POSCH, TE BULGRIN, JR AF MOODY, JM RUBAL, BJ POSCH, TE BULGRIN, JR TI COMPARISON OF COHEN-CLASS TIME-FREQUENCY DISTRIBUTIONS OF INTRACARDIAC HEART SOUNDS IN MAN SO JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY LA English DT Meeting Abstract C1 BROOKE ARMY MED CTR,FT SAM HOUSTON,TX 78234. HUGHES AIRCRAFT CO,FULLERTON,CA 92634. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0735-1097 J9 J AM COLL CARDIOL JI J. Am. Coll. Cardiol. PD FEB PY 1994 SI SI BP A267 EP A267 PG 1 WC Cardiac & Cardiovascular Systems SC Cardiovascular System & Cardiology GA PP518 UT WOS:A1994PP51801054 ER PT J AU MICHAEL, NL VAHEY, MT DARCY, L EHRENBERG, PK MOSCA, JD RAPPAPORT, J REDFIELD, RR AF MICHAEL, NL VAHEY, MT DARCY, L EHRENBERG, PK MOSCA, JD RAPPAPORT, J REDFIELD, RR TI NEGATIVE-STRAND RNA TRANSCRIPTS ARE PRODUCED IN HUMAN-IMMUNODEFICIENCY-VIRUS TYPE 1-INFECTED CELLS AND PATIENTS BY A NOVEL PROMOTER DOWN-REGULATED BY TAT SO JOURNAL OF VIROLOGY LA English DT Article ID MOUSE MITOCHONDRIAL-DNA; LONG TERMINAL REPEAT; HTLV-III; PRECISE ASSIGNMENT; REGULATORY ELEMENT; PLUS STRAND; T-CELLS; EXPRESSION; HIV-1; SEQUENCE AB Current understanding of human immunodeficiency virus type 1 (HIV-I) transcription is based on unidirectional expression of transcripts with positive-strand polarity from the 5' long terminal repeat. We now report HIV-1 transcripts' with negative-strand polarity obtained from acutely and chronically infected cell lines by use of a template orientation-specific reverse transcriptase-PCR assay. These findings were confirmed in natural infection by analysis of RNA derived from peripheral blood mononuclear cell samples from 15 HIV-l-infected patients. A cDNA derived from a 2.3-kb polyadenylated HIV-I RNA with negative-strand polarity which encodes a highly conserved 189-amino-acid open reading frame antiparallel to the envelope gene was isolated from acutely infected A3.01 cells. Through use of reporter gene constructions, we further found that a novel negative-strand promoter functions within the negative response element of the 3' long terminal repeat, which is downregulated by coexpression of Tat. Site-directed mutagenesis experiments demonstrated that NF-kappa B I and USF sites are crucial for negative-strand promoter activity. These data extend the coding capacity of HIV-1 and suggest a cole for antisense regulation of the viral life cycle, C1 WALTER REED ARMY INST RES,DEPT RETROVIRAL RES,ROCKVILLE,MD 20850. HENRY M JACKSON FDN,ROCKVILLE,MD 20850. NIDR,ORAL MED LAB,BETHESDA,MD 20892. NR 41 TC 51 Z9 52 U1 0 U2 1 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0022-538X J9 J VIROL JI J. Virol. PD FEB PY 1994 VL 68 IS 2 BP 979 EP 987 PG 9 WC Virology SC Virology GA MW252 UT WOS:A1994MW25200047 PM 8289399 ER PT J AU FREUND, BJ OBRIEN, C YOUNG, AJ AF FREUND, BJ OBRIEN, C YOUNG, AJ TI ALCOHOL INGESTION AND TEMPERATURE REGULATION DURING COLD-EXPOSURE SO JOURNAL OF WILDERNESS MEDICINE LA English DT Review DE COLD EXPOSURE; HYPOTHERMIA; POIKILOTHERMIC; THERMOREGULATION; ALCOHOL INGESTION; HYPOGLYCEMIA AB Outdoor or wilderness activities are sometimes combined with the ingestion of alcoholic beverages. Despite the feeling of warmth induced by alcohol ingestion, it is widely believed that alcohol actually causes a decrease in body core temperature and increases the risk of hypothermia during cold exposure. However, the literature on the effects of alcohol ingestion on thermoregulation is conflicting. This review summarizes the scientific findings concerning this topic and identifies a number of confounding factors that may explain the conflicting observations. These factors include quantity of alcohol ingested, severity of the cold stress, nutritional state of the individual, composition of the drink, body composition of the individual and alcohol tolerance of the individual. When these factors are considered, it appears that (1) alcohol acts as a poikilothermic agent, causing a reduction in body core temperature during cold exposure, with the magnitude of reduction related to blood alcohol concentration, (2) the severity of cold and the individual's body composition modify the thermoregulatory effects of alcohol, and (3) hypoglycemia greatly exacerbates the reduction in body temperature caused by alcohol ingestion. Furthermore, the primary mechanism by which alcohol ingestion exacerbates the fall in body core temperature during cold exposure appears to be via an impairment of shivering thermogenesis resulting from alcohol-induced hypoglycemia, rather than by increasing heat dissipation via vasodilation as commonly believed. RP FREUND, BJ (reprint author), USA,ENVIRONM MED RES INST,DIV THERMAL PHYSIOL & MED,NATICK,MA 01760, USA. NR 0 TC 8 Z9 8 U1 2 U2 11 PU CHAPMAN HALL LTD PI LONDON PA 2-6 BOUNDARY ROW, LONDON, ENGLAND SE1 8HN SN 0953-9859 J9 J WILDERNESS MED PD FEB PY 1994 VL 5 IS 1 BP 88 EP 98 DI 10.1580/0953-9859-5.1.88 PG 11 WC Medicine, General & Internal; Physiology SC General & Internal Medicine; Physiology GA NB011 UT WOS:A1994NB01100011 ER PT J AU EISENHAUER, CL MCCULLEN, AH ICHIMURA, WM CLAYBAUGH, JR AF EISENHAUER, CL MCCULLEN, AH ICHIMURA, WM CLAYBAUGH, JR TI TECHNIQUE FOR PLACEMENT OF CHRONIC 3RD CEREBROVENTRICULAR CANNULA IN FEMALE GOATS (CAPRA-HIRCUS) SO LABORATORY ANIMAL SCIENCE LA English DT Article ID CONTRAST-MEDIA; MYELOGRAPHY AB A practical method for chronic catheterization of the third cerebroventricular space in goats was developed by using a stereotaxic device. In female goats of various ages and weights, a stereotaxically mounted drill was positioned at an angle of 11.5 degrees with the tip of the drill bit located at a skull reference point 2 to 3 mm rostral to the posterior border of Bregma (intersection of the coronal with the sagittal sutures). The hole that was drilled served as the guide for a tight-fitting cannula, which was 20-gauge stainless steel with a stylet. The cannula was advanced by hand to a depth of approximately 40 mm from the top of the skull, positioning the cannula tip in the anterior region of the third ventricle anterior to the massa intermedia. Copious flow of cerebrospinal fluid verified appropriate positioning. The cannula was anchored with dental acrylic and a subcutaneous port system attached via plastic tubing. Cannula placement was assessed after surgery by use of fluoroventriculography. Cannula patency was maintained for 23 months. Minimal complications were seen, maintenance was minimal, and animals were allowed complete freedom of movement with no requirement for jackets or wraps and were used in several consecutive studies. No anesthetic complications were noticed. RP EISENHAUER, CL (reprint author), TRIPLER ARMY MED CTR,DEPT CLIN INVEST,HONOLULU,HI 96859, USA. NR 12 TC 0 Z9 0 U1 0 U2 0 PU AMER ASSOC LABORATORY ANIMAL SCIENCE PI CORDOVA PA 70 TIMBERCREEK DR, SUITE 5, CORDOVA, TN 38018 SN 0023-6764 J9 LAB ANIM SCI JI Lab. Anim. Sci. PD FEB PY 1994 VL 44 IS 1 BP 55 EP 59 PG 5 WC Veterinary Sciences; Zoology SC Veterinary Sciences; Zoology GA NB052 UT WOS:A1994NB05200010 PM 8007662 ER PT J AU PURDY, EM AF PURDY, EM TI THE INTEGRATED PETROLEUM, OILS AND LUBRICANTS DATA SYSTEM FOR THE MILITARY SO LUBRICATION ENGINEERING LA English DT Article RP PURDY, EM (reprint author), USA,BELVOIR RES DEV & ENGN CTR,FT BELVOIR,VA 22060, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC TRIBOLOGISTS & LUBRICATION ENGINEERS PI PARK RIDGE PA 838 BUSSE HIGHWAY, PARK RIDGE, IL 60068 SN 0024-7154 J9 LUBR ENG JI Lubric. Eng. PD FEB PY 1994 VL 50 IS 2 BP 106 EP 108 PG 3 WC Engineering, Mechanical SC Engineering GA MW932 UT WOS:A1994MW93200001 ER PT J AU JOHNSON, MJ FRIEDL, KE FRYKMAN, PN MOORE, RJ AF JOHNSON, MJ FRIEDL, KE FRYKMAN, PN MOORE, RJ TI LOSS OF MUSCLE MASS IS POORLY REFLECTED IN GRIP STRENGTH PERFORMANCE IN HEALTHY-YOUNG MEN SO MEDICINE AND SCIENCE IN SPORTS AND EXERCISE LA English DT Article DE ISOMETRIC HANDGRIP STRENGTH; BODY COMPOSITION; MILITARY PERSONNEL; LIFT CAPACITY; CLEAN LIFT; WEIGHT REDUCTION ID AGE; BODY AB Isometric maximal handgrip strength (GS(max)) has been used as an expedient test of overall muscle strength and index of fat-free mass (FFM). We tested this relationship in 55 fit young men undergoing high rates of FFM loss in an 8.5-wk military training course involving multiple stressors including nutritionally uncomplicated energy deficit. GS(max) was measured by a hand dynamometer interfaced with a computer providing visual feedback; another strength test, measuring dynamic strength of larger muscle groups (Clean(sim)), was also performed. GS(max) did not change (530 +/- 57 vs 529 +/- 63 N) in the face of a 15.6% loss of body weight (12.1 +/- 3.4 (SD) kg), including 6.9% loss of FFM (4.6 +/- 2.6 kg), but Clean(sim) decremented significantly (77.4 +/- 9.6 to 58.7 +/- 8.9 kg) and changes were significantly correlated with Delta FFM for GS(max) (r = 0.31) and Clean(sim) (r = 0.49). We conclude that GS(max) is not a good representation of changes in total FFM in healthy young men even though it appears to be useful in more severely catabolic patients with extreme losses of FFM and in pubertal boys making large gains in FFM. Other aspects of physical performance are clearly affected by high rates of weight loss, as demonstrated by decrements in the Clean(sim) and its stronger relationship to Delta FFM. C1 USA,ENVIRONM MED RES INST,DIV OCCUPAT PHYSIOL,NATICK,MA 01760. OI Friedl, Karl/0000-0002-3134-8427 NR 24 TC 29 Z9 29 U1 1 U2 3 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0195-9131 J9 MED SCI SPORT EXER JI Med. Sci. Sports Exerc. PD FEB PY 1994 VL 26 IS 2 BP 235 EP 240 DI 10.1249/00005768-199402000-00015 PG 6 WC Sport Sciences SC Sport Sciences GA MV687 UT WOS:A1994MV68700015 PM 8164542 ER PT J AU COLBECK, SC AF COLBECK, SC TI BOTTOM TEMPERATURES OF SKATING SKIS ON SNOW SO MEDICINE AND SCIENCE IN SPORTS AND EXERCISE LA English DT Note DE FRICTION; FRICTIONAL HEATING; GLIDING; TRAINING; WAXING AB Thermocouples provide information about ski and skier performances and snow conditions. V1 skating superimposed a strong, cyclic signal on the general heating due to friction. The power spectra of these cycles gave information about the skier's technique. The greatest temperature response at the base of a skating ski was just behind the foot, where the ski is heavily loaded. The longitudinal profiles showed generally increasing temperatures along the length of the ski. Harder, more durable waxes are needed behind the foot, where most of the weight is carried, but the gliding temperatures are highest there. Heating increased with both speed and solar input. Solar radiation absorption hears the ski base directly and raises its temperature considerably. The color of the ski base and the amount of sunshine should be considered when choosing a wax. RP COLBECK, SC (reprint author), COLD REG RES & ENGN LAB,72 LYME RD,HANOVER,NH 03755, USA. NR 7 TC 10 Z9 10 U1 0 U2 9 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0195-9131 J9 MED SCI SPORT EXER JI Med. Sci. Sports Exerc. PD FEB PY 1994 VL 26 IS 2 BP 258 EP 262 DI 10.1249/00005768-199402000-00019 PG 5 WC Sport Sciences SC Sport Sciences GA MV687 UT WOS:A1994MV68700019 PM 8164546 ER PT J AU MOREY, AF BRITTON, B DESHON, GE KIMURA, LH DRESNER, ML CRAIN, TW AF MOREY, AF BRITTON, B DESHON, GE KIMURA, LH DRESNER, ML CRAIN, TW TI PROLIFERATIVE ACTIVITY AS AN ADJUNCT IN THE DIAGNOSIS OF PROSTATIC ADENOCARCINOMA SO MILITARY MEDICINE LA English DT Article AB Sixty-nine men underwent transrectal ultrasound-directed biopsy of the prostate. One biopsy core from each side of each gland was sent for DNA flow cytometric testing (138 total specimens). Results were correlated with findings from standard he matoxylin and eosin staining of other cores. Twelve patients (17.4%) had biopsies with histopathologic evidence of prostatic carcinoma. Of 57 patients (82.6%) with benign biopsies, two had stage A prostate adenocarcinoma noted on subsequent transurethral resection. Proliferative activity was calculated from DNA histograms by adding the percentage of nuclei in the proliferative (S and G2/M) phases of the cell-division cycle. Mean proliferative activity for the malignant group (19.08) was significantly higher (p < 0.001) than that of the benign group (13.43). Inflammation was associated with elevated proliferative activity scores among benign glands. Proliferative activity is an objective, easily obtainable indicator of the biological activity of a population of cells which, when elevated, may suggest a need for repeat biopsy in patients with otherwise normal prostate biopsies. Flow cytometry may have value as a complement to standard histologic analysis of transrectal core biopsies in the diagnosis of prostate cancer. RP MOREY, AF (reprint author), TRIPLER ARMY MED CTR,DEPT SURG,UROL SERV,HONOLULU,HI 96859, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD FEB PY 1994 VL 159 IS 2 BP 91 EP 94 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA NB549 UT WOS:A1994NB54900003 PM 8202255 ER PT J AU STEINBAUM, SS CUCINELL, S HATHAWAY, TK AF STEINBAUM, SS CUCINELL, S HATHAWAY, TK TI EFFECTS OF CRYOPRECIPITATE ON THE HEALING OF CHRONIC WOUNDS SO MILITARY MEDICINE LA English DT Article AB Basic research has promise for clinical wound healing. Purified wound healing growth factors are not available for clinical use. but they are present in plasma and platelets and have been used in patients. Chronic wounds would seem to be good for study since the wound surface is easily measured and the patient is anxious for progress. We have done a double-blinded pilot study using autologous cryoprecipitate on chronic wounds. Three of six patients showed wound healing progress; but only one patient's wounds healed permanently. One patient developed new diabetic ulcers, and one patient failed to keratinize epithelialized skin, Cryoprecipitate may promote wound healing, but further work awaits more purified healing factors. Simple measurement of the surface area of a chronic wound may not be adequate to describe all the processes of healing. RP STEINBAUM, SS (reprint author), WALTER REED ARMY MED CTR,DEPT SURG,GEN SURG SERV,WASHINGTON,DC 20307, USA. NR 0 TC 2 Z9 2 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD FEB PY 1994 VL 159 IS 2 BP 105 EP 108 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA NB549 UT WOS:A1994NB54900006 PM 8202233 ER PT J AU GOUGE, SF DANIELS, DJ SMITH, CE AF GOUGE, SF DANIELS, DJ SMITH, CE TI EXACERBATION OF ASTHMA AFTER PYRIDOSTIGMINE DURING OPERATION DESERT-STORM SO MILITARY MEDICINE LA English DT Article AB Pyridostigmine was first used extensively during Operation Desert Storm for prophylaxis against the effects of nerve agents. After initial reports of asthma exacerbations following its use, we gave 10 asthmatic and 6 non-asthmatic soldiers a 30-mg dose of pyridostigmine. We found no changes in forced vital capacity in any of the soldiers, but observed exacerbation of asthma symptoms in seven of the asthmatics. Severity of the exacerbation correlated best with severity of asthma in the desert and inversely with body weight. The irritant effect of the dust may predispose asthmatics to worsen after pyridostigmine, an effect not seen in the laboratory. RP GOUGE, SF (reprint author), BROOKE ARMY MED CTR,DEPT MED,NEPHROL SERV,SAN ANTONIO,TX 78234, USA. NR 0 TC 12 Z9 13 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD FEB PY 1994 VL 159 IS 2 BP 108 EP 111 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA NB549 UT WOS:A1994NB54900007 PM 8202234 ER PT J AU LEE, S RAKER, T CHISICK, MC AF LEE, S RAKER, T CHISICK, MC TI PSYCHOSOCIAL FACTORS INFLUENCING SMOKELESS TOBACCO USE BY TEENAGE MILITARY DEPENDENTS SO MILITARY MEDICINE LA English DT Article AB Using bivariate and logistic regression analysis, we explored psychosocial correlates of smokeless tobacco (SLT) use in a sample of 2,257 teenage military dependents. We built separate regression models for males and females to explain triers and users of SLT. Results show female and male triers share five factors regarding SLT use-parental and peer approval, trying smoking, relatives using SLT, and athletic team membership. Male trial of SLT was additionally associated with race, difficulty in purchasing SLT, relatives who smoke, current smoking, and belief that SLT can cause mouth cancer. Male use of SLT was associated with race, seeing a dentist regularly, SLT counseling by a dentist, parental approval, trying and current smoking, and grade level. In all models, trying smoking was the strongest explanatory variable. Relatives and peers exert considerable influence on SLT use. Few triers or users had received SLT counseling from their dentist despite high dental utilization rates. RP LEE, S (reprint author), USA,INST DENT RES,EPIDEMIOL SECT,FT GEORGE G MEADE,MD 20755, USA. NR 0 TC 7 Z9 7 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD FEB PY 1994 VL 159 IS 2 BP 112 EP 117 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA NB549 UT WOS:A1994NB54900008 PM 8202235 ER PT J AU KING, N ROBERTS, DE EDWARDS, JSA MORIZEN, RD ASKEW, EW AF KING, N ROBERTS, DE EDWARDS, JSA MORIZEN, RD ASKEW, EW TI COLD-WEATHER FIELD FEEDING - AN OVERVIEW SO MILITARY MEDICINE LA English DT Article AB Extremely cold environments are a challenge to military field feeding operations due to freezing and inadequate intakes of rations and water. The U.S. Army Research Institute of Environmental Medicine conducted a series of three cold-weather field feeding studies to test, modify, and contribute data for the development of Cold-Weather Feeding Doctrine. Conclusions from these studies show that command emphasis is essential for ration and water storage and distribution to prevent freezing, and adequate ration and water consumption to prevent weight loss and dehydration. Since any ration mix can be configured to meet cold-weather feeding requirements, the decision of which ration to use should be based on logistical support and constraints, mission requirements, and water availability. RP KING, N (reprint author), USA,ENVIRONM MED RES INST,DIV MIL NUTR,NATICK,MA 01760, USA. NR 0 TC 0 Z9 0 U1 0 U2 4 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD FEB PY 1994 VL 159 IS 2 BP 121 EP 126 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA NB549 UT WOS:A1994NB54900010 PM 8202237 ER PT J AU PATTERSON, HS WOOLLEY, TW LEDNAR, WM AF PATTERSON, HS WOOLLEY, TW LEDNAR, WM TI FOOT BLISTER RISK-FACTORS IN AN ROTC SUMMER CAMP POPULATION SO MILITARY MEDICINE LA English DT Article AB Data that establish risk factors for foot blister morbidity among ROTC cadets at summer camp are presented. The subjective blister attack rate was 42.1 per 100 cadets. Women had a relative risk of 1.6 that of men (p < 0.001). Cadets with a history of blisters in the 2 years before camp had an increased relative risk of blister formation. Cadets who reported wearing their boots less than 20 hours per week during the 2 weeks immediately before camp had elevated risk. Other factors are examined. These data suggest that the foot must become conditioned to its footwear to prevent blister formation. RP PATTERSON, HS (reprint author), WALTER REED ARMY MED CTR,DEPT PEDIAT,WASHINGTON,DC 20307, USA. NR 0 TC 11 Z9 11 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD FEB PY 1994 VL 159 IS 2 BP 130 EP 135 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA NB549 UT WOS:A1994NB54900012 PM 8202239 ER PT J AU SIMPSON, MB MURPHY, KP CHAMBERS, HG BUCKNELL, AL AF SIMPSON, MB MURPHY, KP CHAMBERS, HG BUCKNELL, AL TI THE EFFECT OF POSTOPERATIVE WOUND DRAINAGE REINFUSION IN REDUCING THE NEED FOR BLOOD-TRANSFUSIONS IN ELECTIVE TOTAL JOINT ARTHROPLASTY - A PROSPECTIVE, RANDOMIZED STUDY SO ORTHOPEDICS LA English DT Article AB A prospective, randomized study was conducted in 24 patients using the Solcotrans Orthopaedic Drainage Reinfusion System (Smith and Nephew Richards Inc, Memphis, Tenn) for postoperative blood salvage in total joint arthroplasty, The amount of postoperative autologous blood salvage averaged 946 mL. Only 25% of the study group required postoperative transfusions, compared to 83% of the control group (P =.016). In total knee arthroplasties, only 11% of the study group required transfusions, compared to 78% of the control group (P = .018). There were no transfusion reactions, infectious complications, or coagulopathies. Postoperative blood salvage is a safe, reliable, and effective source of autologous blood. C1 BROOKE ARMY MED CTR,DEPT SURG,ORTHOPED SURG SERV,FT SAM HOUSTON,TX 78234. NR 0 TC 34 Z9 36 U1 0 U2 1 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 SN 0147-7447 J9 ORTHOPEDICS JI Orthopedics PD FEB PY 1994 VL 17 IS 2 BP 133 EP 137 PG 5 WC Orthopedics SC Orthopedics GA MW202 UT WOS:A1994MW20200007 PM 8190677 ER PT J AU PATOW, CA BARTELS, J DODD, KT AF PATOW, CA BARTELS, J DODD, KT TI TYMPANIC MEMBRANE PERFORATION IN SURVIVORS OF A SCUD MISSILE EXPLOSION SO OTOLARYNGOLOGY-HEAD AND NECK SURGERY LA English DT Article ID BLAST INJURY; EAR AB On February 25, 1990, an Iraqi SCUD missile exploded inside a building housing United States military personnel in Dhahran, Kingdom of Saudi Arabia. One hundred seventy-two individuals who were near the impact site at the time of the blast were interviewed and examined to determine blast injury to the ear. Tympanic membrane (TM) perforation was used as the clinical marker for aural blast injury. Thirty-four personnel had unilateral TM perforation and 28 had bilateral TM perforation. Eighty-six sustained sufficient injury to be hospitalized. Fifty-nine of hospitalized personnel (70%) had TM perforation. Of a total of 90 TM perforations, 39% were estimated to be 25% or less of the tympanic membrane surface area, 36% were 26% to 50%, 16% were 51% to 75%, and 10% were greater than 75%. Morphology of the perforations and estimated proximity to the blast were documented. Personnel distant from the blast, in open doorways or wearing headphones, had relative protection from TM perforation. Historic nuclear blast data were used to estimate the SCUD blast waveform based on measurements of the SCUD impact crater. A mathematical model based on the estimated waveform was validated against the actual field data by comparing the proximity and incidence of TM perforations in the SCUD missile explosion. C1 USA,EVACUAT HOSP 85,DHAHRAN,SAUDI ARABIA. USA,EVACUAT HOSP 207,DHAHRAN,SAUDI ARABIA. WALTER REED ARMY MED CTR,DEPT RESP RES,DIV MED,WASHINGTON,DC. NR 16 TC 12 Z9 12 U1 0 U2 0 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0194-5998 J9 OTOLARYNG HEAD NECK JI Otolaryngol. Head Neck Surg. PD FEB PY 1994 VL 110 IS 2 BP 211 EP 221 PG 11 WC Otorhinolaryngology; Surgery SC Otorhinolaryngology; Surgery GA MX869 UT WOS:A1994MX86900011 PM 8108156 ER PT J AU IWU, MM JACKSON, JE SCHUSTER, BG AF IWU, MM JACKSON, JE SCHUSTER, BG TI MEDICINAL-PLANTS IN THE FIGHT AGAINST LEISHMANIASIS SO PARASITOLOGY TODAY LA English DT Article ID CUTANEOUS LEISHMANIASIS; CHEMOTHERAPY; MECHANISM; DRUGS AB Despite the tremendous progress made in the understanding of the molecular biology of Leishmania and the clinical possibilities presented by some experimental chemotherapeutic agents, no new drugs have been developed for the treatment of leishmaniasis since the introduction of the pentavalent antimonials more than 50 years ego. As reviewed here by Maurice M. Iwu, Joan E. Jackson and Brian G. Schuster, recognition of the current extensive use of herbal therapy in Leishmania-endemic regions has renewed interest in evaluation of plant remedies used in traditional medicine as sources of potential antileishmanials. RP IWU, MM (reprint author), WALTER REED ARMY INST RES,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307, USA. NR 34 TC 79 Z9 84 U1 0 U2 4 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB SN 0169-4758 J9 PARASITOL TODAY JI Parasitol. Today PD FEB PY 1994 VL 10 IS 2 BP 65 EP 68 DI 10.1016/0169-4758(94)90398-0 PG 4 WC Parasitology SC Parasitology GA MV152 UT WOS:A1994MV15200010 PM 15275504 ER PT J AU DEMERS, DM CHAN, DS BASS, JW AF DEMERS, DM CHAN, DS BASS, JW TI ANTIMICROBIAL DRUG SUSPENSIONS - A BLINDED COMPARISON OF TASTE OF 12 COMMON PEDIATRIC DRUGS INCLUDING CEFIXIME, CEFPODOXIME, CEFPROZIL AND LORACARBEF SO PEDIATRIC INFECTIOUS DISEASE JOURNAL LA English DT Article DE TASTE COMPARISON; DRUG SUSPENSIONS; CEFIXIME; CEFPROZIL; LORACARBEF AB We conducted a blinded taste test evaluating 12 antimicrobial suspensions by smell, texture, taste, aftertaste and overall acceptance. Drugs received cumulative scores in each category as well as a total score ranking. Overall Lorabid(R) scored highest but not significantly higher than Keflex(R), Suprax(R) and Ceclor(R), all of which scored higher than the other test drugs. Cefzil(R) and Augmentin(R) scored just below this group of drugs and higher than all other test drugs. Vantin(R) was inferior to these drugs primarily because of its low score in aftertaste. It was ranked along with V-Cillin-K(R), Veetids(R), Sulfatrim(R) and Pediazole(R), the lowest scoring group of drugs other than Dynapen(R) which scored lower than all other test drugs. No difference overall was detected between the two penicillin VK suspensions evaluated, V-Cillin-K(R) and Veetids(R). C1 TRIPLER ARMY MED CTR,DEPT PEDIAT,HONOLULU,HI 96859. TRIPLER ARMY MED CTR,PHARM SERV,HONOLULU,HI 96859. NR 6 TC 54 Z9 54 U1 0 U2 2 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0891-3668 J9 PEDIATR INFECT DIS J JI Pediatr. Infect. Dis. J. PD FEB PY 1994 VL 13 IS 2 BP 87 EP 89 DI 10.1097/00006454-199402000-00001 PG 3 WC Immunology; Infectious Diseases; Pediatrics SC Immunology; Infectious Diseases; Pediatrics GA MW838 UT WOS:A1994MW83800001 PM 8190556 ER PT J AU EASA, D MUNDIE, TG FINN, KC BALARAMAN, V STEVENS, EL TAKENAKA, W UYEHARA, CFT AF EASA, D MUNDIE, TG FINN, KC BALARAMAN, V STEVENS, EL TAKENAKA, W UYEHARA, CFT TI THE EFFECTS OF REVERSING DISTENDING PRESSURE SEQUENCES IN THE NEONATAL PIGLET SO PEDIATRIC PULMONOLOGY LA English DT Article DE PREVIOUS LUNG INFLATION; END-EXPIRATORY LUNG VOLUME; LUNG COMPLIANCE ID RESPIRATORY MECHANICS; INFLATION-DEFLATION; SURFACE-TENSION; INFANTS; LUNG; ATELECTASIS; ANESTHESIA AB We studied different sequences of lung inflation in ventilated newborn piglets with normal lungs in order to determine the effects of sequence, magnitude and duration of distending pressure on pulmonary function, and/or hemodynamics. End-expiratory pressure was varied using a continuous negative extrathoracic pressure (CNEP) device. Three groups of ventilated piglets with normal lungs were exposed to 2 cmH(2)O increments of CNEP from -2 to -12 cmH(2)O, and to decrements from -12 to -2 cmH(2)O, or to only -6 cmH(2)O. Lung inflation sequence, magnitude of inflation pressure, and duration of inflation had significant effects on end-expiratory lung volume and lung compliance at numerically equivalent pressure levels. End-expiratory lung volume and lung compliance varied (at four and five of six inflation pressures studied) by as much as 68% and 104%, respectively. Hemodynamic effects of the lung inflation sequence were more variable; those found to be different at numerically equivalent pressure levels were associated with changes in lung compliance and ventilation. Differences in pulmonary mechanics can best be explained by the effects of lung inflation on alveolar recruitment versus overinflation. (C) 1994 Wiley-Liss, Inc. C1 JOHN A BURNS SCH MED,KAPIOLANI MED CTR WOMEN & CHILDREN,DEPT RESP CARE,HONOLULU,HI. TRIPLER ARMY MED CTR,DEPT CLIN INVEST,HONOLULU,HI 96859. TRIPLER ARMY MED CTR,DEPT PEDIAT,HONOLULU,HI. RP EASA, D (reprint author), JOHN A BURNS SCH MED,KAPIOLANI MED CTR WOMEN & CHILDREN,DEPT PEDIAT,1319 PUNAHOU ST,HONOLULU,HI 96826, USA. NR 32 TC 5 Z9 5 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 8755-6863 J9 PEDIATR PULM JI Pediatr. Pulmonol. PD FEB PY 1994 VL 17 IS 2 BP 97 EP 105 DI 10.1002/ppul.1950170205 PG 9 WC Pediatrics; Respiratory System SC Pediatrics; Respiratory System GA MU089 UT WOS:A1994MU08900004 PM 8165044 ER PT J AU SAWYER, TF WESENSTEN, NJ AF SAWYER, TF WESENSTEN, NJ TI ANCHORING EFFECTS ON JUDGMENT, ESTIMATION, AND DISCRIMINATION OF NUMEROSITY SO PERCEPTUAL AND MOTOR SKILLS LA English DT Article AB Three experiments (N - 234) examined anchoring effects on judgement, estimation, and discrimination of numerosity. Subjects were anchored by preexposing them to random dot patterns with a mean quantity of 25, 50, or 75 dots. Subsequent testing with patterns having greater or less numerosity than the anchoring point resulted in predictable effects, including positive or negative contrast effects for numerosity judgements (Exp. 1), positive or negative contrast for the numerical estimation of quantity (Exp. 2), and a larger number of errors when subjects attempted simultaneous discrimination between two dot patterns (Exp. 3). The results extend previous findings for anchoring effects to the stimulus dimension of numerosity. C1 WALTER REED ARMY INST RES,WASHINGTON,DC 20307. RP SAWYER, TF (reprint author), N CENT COLL,DEPT PSYCHOL,30 N BRAINARD,NAPERVILLE,IL 60566, USA. NR 8 TC 4 Z9 4 U1 1 U2 3 PU PERCEPTUAL MOTOR SKILLS PI MISSOULA PA PO BOX 9229, MISSOULA, MT 59807 SN 0031-5125 J9 PERCEPT MOTOR SKILL JI Percept. Mot. Skills PD FEB PY 1994 VL 78 IS 1 BP 91 EP 98 PG 8 WC Psychology, Experimental SC Psychology GA MW360 UT WOS:A1994MW36000018 PM 8177695 ER PT J AU SANNA, LJ PUSECKER, PA AF SANNA, LJ PUSECKER, PA TI SELF-EFFICACY, VALENCE OF SELF-EVALUATION, AND PERFORMANCE SO PERSONALITY AND SOCIAL PSYCHOLOGY BULLETIN LA English DT Article ID SOCIAL FACILITATION; REGULATORY PROCESSES; TASK-PERFORMANCE; MOTIVATION; ENHANCEMENT; FAILURE; ANXIETY; MODEL AB In two experiments, self-efficacy theory was used to conceptualize the effect of efficacy expectancies and valence of self-evaluation on performance. In Experiment 1, efficacy expectancies were manipulated by practice item difficulty and feedback, and self-evaluation was manipulated by providing a standard of comparison. In Experiment 2, efficacy expectancies developed spontaneously while participants performed easy or difficult tasks, and the potential for self-evaluation was crossed with the potential for experimenter evaluation. In both experiments, as predicted, in the high-efficacy condition, self-evaluation participants performed better than no-self-evaluation participants, whereas in the low-efficacy condition, self-evaluation participants performed worse than no-self-evaluation participants. In addition, in Experiment 2, the equivalence of self-evaluation and experimenter evaluation was demonstrated. Implications for self-efficacy and self-evaluation processes are discussed. C1 BUCKNELL UNIV,LEWISBURG,PA 17837. US MIL ACAD,W POINT,NY 10996. NR 55 TC 22 Z9 22 U1 2 U2 4 PU SAGE PUBLICATIONS INC PI THOUSAND OAKS PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 SN 0146-1672 J9 PERS SOC PSYCHOL B JI Pers. Soc. Psychol. Bull. PD FEB PY 1994 VL 20 IS 1 BP 82 EP 92 DI 10.1177/0146167294201008 PG 11 WC Psychology, Social SC Psychology GA MU287 UT WOS:A1994MU28700008 ER PT J AU MANKA, AS AF MANKA, AS TI DETERMINATION OF WEAK DECAY-RATES BY MONITORING COUPLED STRONG TRANSITIONS SO PHYSICAL REVIEW A LA English DT Article ID QUANTUM JUMPS; RESONANCE FLUORESCENCE; OSCILLATOR AB We propose a method, which we call the coherent-coupling approach, to determine a slow spontaneous decay rate by coupling coherently a weak atomic transition to a strong one. This approach allows the indirect measurement of a small decay rate from the fast Fourier transform of the time-dependent intensity oscillations of the strong transition, and can be viewed as an alternative to the method of quantum jumps. RP MANKA, AS (reprint author), USA,MISSILE COMMAND,AMSMI,RD,WS,ST,REDSTONE ARSENAL,AL 35898, USA. NR 14 TC 1 Z9 1 U1 0 U2 0 PU AMERICAN PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1050-2947 J9 PHYS REV A JI Phys. Rev. A PD FEB PY 1994 VL 49 IS 2 BP 1260 EP 1265 DI 10.1103/PhysRevA.49.1260 PG 6 WC Optics; Physics, Atomic, Molecular & Chemical SC Optics; Physics GA MW352 UT WOS:A1994MW35200082 ER PT J AU NEWSOM, RK BRUCE, CW AF NEWSOM, RK BRUCE, CW TI THE DYNAMICS OF FIBROUS AEROSOLS IN A QUIESCENT ATMOSPHERE SO PHYSICS OF FLUIDS LA English DT Article ID LONG SLENDER BODIES; VISCOUS-FLUID; FLOW; PARTICLES; MOTION AB Measurements of the orientational properties of small fibrous graphite aerosols in free fall through air have been performed. The fibers have lengths on the order of millimeters and diameters on the order of microns. Estimates of the Reynolds number based on the fiber's half-length and terminal velocity are on the order of 1. Measurements of the relative extinction in selective polarizations of microwave radiation upon transmission through a cloud of falling fibers in dilute concentration as well as direct photographic measurements indicate the fibers exhibit a tendency to assume a stable orientation with their long axes horizontal under quiescent conditions. Terminal velocities were found to range from 2.5 to 3 cmA. Photographic measurements on single fibers were also made of the rate at which the fibers settle into their stable orientation given an initial arbitrary orientation. Orientational stabilization times, otherwise referred to as orientational relaxation time, are typically on the order of 3 to 5 s; this is mostly dependent on initial orientation. The measured transient angular motion of the fibers is compared with a proposed model of the motion. The model shows qualitative agreement with observations. C1 NEW MEXICO STATE UNIV,LAS CRUCES,NM 88003. RP NEWSOM, RK (reprint author), USA,RES LAB,WHITE SANDS MISSILE RANGE,NM 88002, USA. NR 15 TC 7 Z9 7 U1 0 U2 1 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 1070-6631 J9 PHYS FLUIDS JI Phys. Fluids PD FEB PY 1994 VL 6 IS 2 BP 521 EP 530 DI 10.1063/1.868347 PN 1 PG 10 WC Mechanics; Physics, Fluids & Plasmas SC Mechanics; Physics GA NA738 UT WOS:A1994NA73800008 ER PT J AU LEVY, FE HOLLINGER, JO SZACHOWICZ, EH AF LEVY, FE HOLLINGER, JO SZACHOWICZ, EH TI EFFECT OF A BIORESORBABLE FILM ON REGENERATION OF CRANIAL BONE SO PLASTIC AND RECONSTRUCTIVE SURGERY LA English DT Article ID GROWTH AB Regeneration of cranial bone is usually accomplished with autografts, banked bone, or both. The effect also may be obtained by using a properly engineered alloplastic barrier. Our group assessed histomorphometrically the capacity of a bioresorbable film to promote repair of cranial bone in critical-sized defects in 50 rabbits divided over four time periods (4, 8, 16, and 24 weeks). A single circular defect 15 mm in diameter was prepared in each rabbit and either covered with films of polylactic acid (21 mm in diameter, 150 mu m thick) durally and pericranially or left untreated. Only after 24 weeks was there a significant difference (p less than or equal to 0.05) between defects covered with polylactic acid films and those untreated. We conclude that after shorter periods, regardless of covering, prolapse of soft tissue into defects prevented osseous regeneration. We speculate that at 24 weeks, defects treated with films generated new bone as a result of changes in the local milieu conducive to osteoblastic expression. C1 UNIV MINNESOTA,SCH MED,DEPT OTOLARYNGOL,MINNEAPOLIS,MN 55455. WALTER REED ARMY MED CTR,US ARMY INST DENT RES,WASHINGTON,DC. NR 23 TC 42 Z9 42 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0032-1052 J9 PLAST RECONSTR SURG JI Plast. Reconstr. Surg. PD FEB PY 1994 VL 93 IS 2 BP 307 EP 311 DI 10.1097/00006534-199402000-00011 PG 5 WC Surgery SC Surgery GA MU565 UT WOS:A1994MU56500011 PM 8310022 ER PT J AU MILLER, DL CARDELLA, JF CRONAN, JJ DARCY, MD FREEDMAN, AM MATSUMOTO, AH PARKER, BC SANDLER, CM SCHWAB, FJ STOKES, KR THOMAS, HA VENBRUX, AC AF MILLER, DL CARDELLA, JF CRONAN, JJ DARCY, MD FREEDMAN, AM MATSUMOTO, AH PARKER, BC SANDLER, CM SCHWAB, FJ STOKES, KR THOMAS, HA VENBRUX, AC TI CARDIOVASCULAR/INTERVENTIONAL RADIOLOGY SO RADIOLOGY LA English DT Article; Proceedings Paper CT 79th Scientific Assembly and Annual Meeting of the Radiological-Society-of-North-America (RSNA 93) CY NOV 28-DEC 03, 1993 CL CHICAGO, IL SP RADIOL SOC N AMER DE ALCOHOL; ANGIOGRAPHY, TECHNOLOGY; CONTRAST MEDIA; INTERVENTIONAL PROCEDURES, TECHNOLOGY; MAGNETIC RESONANCE (MR), VASCULAR STUDIES; RADIOLOGICAL SOCIETY OF NORTH AMERICA, 79TH SCIENTIFIC ASSEMBLY AND ANNUAL MEETING; SHUNTS, PORTOSYSTEMIC; STENTS AND PROSTHESES C1 PENN STATE UNIV HOSP,HERSHEY,PA. RHODE ISL HOSP,PROVIDENCE,RI. MALLINCKRODT INST RADIOL,ST LOUIS,MO. VIRGINIA COMMONWEALTH UNIV MED COLL VIRGINIA,RICHMOND,VA. UNIV VIRGINIA,HLTH SCI CTR,CHARLOTTESVILLE,VA. ALEXANDRIA HOSP,ALEXANDRIA,VA. UNIV TEXAS,HOUSTON,TX. ARLINGTON HOSP,ARLINGTON,TX. NEW ENGLAND DEACONESS HOSP,BOSTON,MA. UNIV HOSP SYRACUSE,SYRACUSE,NY. JOHNS HOPKINS UNIV HOSP,BALTIMORE,MD. RP MILLER, DL (reprint author), WALTER REED ARMY MED CTR,WASHINGTON,DC, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU RADIOLOGICAL SOC NORTH AMER PI EASTON PA 20TH AND NORTHAMPTON STS, EASTON, PA 18042 SN 0033-8419 J9 RADIOLOGY JI Radiology PD FEB PY 1994 VL 190 IS 2 BP 603 EP 607 PG 5 WC Radiology, Nuclear Medicine & Medical Imaging SC Radiology, Nuclear Medicine & Medical Imaging GA MW444 UT WOS:A1994MW44400067 PM 8284427 ER PT J AU WATKINS, WR BEAN, BL MUNDING, PD AF WATKINS, WR BEAN, BL MUNDING, PD TI LARGE-AREA THERMAL TARGET BOARD - A NEW DESIGN SO REVIEW OF SCIENTIFIC INSTRUMENTS LA English DT Note AB A large area (1.8 m by 1.8 m), uniform temperature, thermal target was used for characterization of phenomena that impact target contrast. The target board is equipped with several bar patterns. It has a unique design that uses a tilted oven surface making it lightweight with near perfect transition between the hot and cold portions of the bar patterns. The oven surface maintains a +/-1 degrees C uniformity when heated to 10-20 degrees C above ambient temperature. C1 OPTIMETR INC,LAS CRUCES,NM 88005. SCI TECHNOL CORP,LAS CRUCES,NM 88001. RP WATKINS, WR (reprint author), USA,RES LAB,WHITE SANDS MISSILE RANGE,NM 88002, USA. NR 9 TC 2 Z9 2 U1 0 U2 0 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0034-6748 J9 REV SCI INSTRUM JI Rev. Sci. Instrum. PD FEB PY 1994 VL 65 IS 2 BP 519 EP 520 DI 10.1063/1.1145117 PG 2 WC Instruments & Instrumentation; Physics, Applied SC Instruments & Instrumentation; Physics GA MX032 UT WOS:A1994MX03200047 ER PT J AU KROUTIL, RT HOUSKY, M SMALL, GW AF KROUTIL, RT HOUSKY, M SMALL, GW TI REAL-TIME DATA-COLLECTION PROGRAMS FOR A COMMERCIAL PASSIVE FT-IR REMOTE SENSOR SO SPECTROSCOPY LA English DT Article ID TRANSFORM INFRARED INTERFEROGRAMS AB Signal processing methods far the analysis of Fourier transform-infrared (FT-IR) interferograms have eliminated the need for a spectral background reference for outdoor open path atmospheric measurements, These methods have allowed the detection and discrimination of chemical vapor species in the presence of a wide variety of spectral interferents, In tutorial fashion, this article describes public-domain data collection and analysis software that has recently been developed for real time detection using a commercial interferometer. C1 USA,CTR EDGEWOOD RES DEV & ENGN,ABERDEEN PROVING GROUND,MD 21010. SPECTRAL CONSULTANTS INC,LAKE FOREST,CA 92630. OHIO UNIV,CTR INTELLIGENT CHEM INSTRUMENTAT,DEPT CHEM,ATHENS,OH 45701. NR 5 TC 20 Z9 20 U1 0 U2 0 PU ADVANSTAR COMMUNICATIONS PI DULUTH PA 131 W FIRST ST, DULUTH, MN 55802 SN 0887-6703 J9 SPECTROSCOPY JI Spectroscopy PD FEB PY 1994 VL 9 IS 2 BP 41 EP & PG 0 WC Spectroscopy SC Spectroscopy GA RF245 UT WOS:A1994RF24500006 ER PT J AU THOMPSON, IM AF THOMPSON, IM TI OBSERVATION ALONE IN THE MANAGEMENT OF LOCALIZED PROSTATE-CANCER - THE NATURAL-HISTORY OF UNTREATED DISEASE SO UROLOGY LA English DT Article ID RADICAL PROSTATECTOMY; ADENOCARCINOMA AB Objective. To review the data from a series of patients with localized prostate cancer managed with observation alone. When available, cancer-specific survival was analyzed. Predictive factors for disease outcome were reviewed. Methods. Series of patients with localized prostate cancer managed with observation alone were reviewed. When available, cancer-specific survival was analyzed. Predictive factors for disease outcome are reviewed. Results. In published trials of observation alone, ten-year cancer-specific survivals of 80-90 percent are realized. Adverse predictors of outcome include higher stage and grade as well as aneuploid tumors. Although tumor progression is more common in patients with adverse predictive factors, adverse outcomes can occur in the larger group of patients with intermediate grade, stage, or tumor volume. Conclusions. Based on a small number of studies of patients with localized prostate cancer managed with observation alone, it appears that this option is reasonable for patients with good predictive factors and for patients with shorter life expectancies. The principal advantage of observation is the avoidance of treatment-related morbidity, but for the patient whose disease progresses during follow-up, disease-related morbidity can occasionally occur RP THOMPSON, IM (reprint author), BROOKE ARMY MED CTR,UROL SERV,SAN ANTONIO,TX 78234, USA. NR 16 TC 13 Z9 13 U1 0 U2 1 PU CAHNERS PUBL CO PI NEW YORK PA 249 WEST 17 STREET, NEW YORK, NY 10011 SN 0090-4295 J9 UROLOGY JI UROLOGY PD FEB PY 1994 VL 43 IS 2 SU S BP 41 EP 46 DI 10.1016/0090-4295(94)90217-8 PG 6 WC Urology & Nephrology SC Urology & Nephrology GA MX906 UT WOS:A1994MX90600009 PM 8116132 ER PT J AU BROWN, AE SINGHARAJ, P WEBSTER, HK PIPITHKUL, J GORDON, DM BOSLEGO, JW KRINCHAI, K SUARCHAWARATANA, P WONGSRICHANALAI, C BALLOU, WR PERMPANICH, B KAIN, KC HOLLINGDALE, MR WITTES, J QUE, JU GROSS, M CRYZ, SJ SADOFF, JC AF BROWN, AE SINGHARAJ, P WEBSTER, HK PIPITHKUL, J GORDON, DM BOSLEGO, JW KRINCHAI, K SUARCHAWARATANA, P WONGSRICHANALAI, C BALLOU, WR PERMPANICH, B KAIN, KC HOLLINGDALE, MR WITTES, J QUE, JU GROSS, M CRYZ, SJ SADOFF, JC TI SAFETY, IMMUNOGENICITY AND LIMITED EFFICACY STUDY OF A RECOMBINANT PLASMODIUM-FALCIPARUM CIRCUMSPOROZOITE VACCINE IN THAI SOLDIERS SO VACCINE LA English DT Article DE PLASMODIUM FALCIPARUM MALARIA VACCINE; RECOMBINANT VACCINE; SPOROZOITE ID PROTEIN REPEAT REGION; MALARIA; SPOROZOITES; ANTIBODIES; HUMANS; INVITRO; VIVAX; IMMUNIZATION; PROTECTION; RESPONSES AB Thai soldiers were vaccinated with a recombinant protein derived from the central repeat region of the circumsporozoite (CS) protein of Plasmodium falciparum conjugated to Toxin A (detoxified) of Pseudomonas aeruginosa (R32Tox-A) to evaluate its safety, immunogenicity and efficacy. In a randomized, double-blind manner, 199 volunteers received either R32Tox-A or a control vaccine at 0, 8 and 16 weeks. Immunization was preformed in a malaria non-transmission area, after completion of which volunteers were deployed to an endemic border area and monitored closely to allow early detection and treatment of infection. The vaccine was found to be safe and to elicit antibody responses in all vaccinees. Peak CS antibody (IgG) concentrations in malaria-experienced vaccinees exceeded those in malaria-naive vaccinees (mean 40.6 versus 16.1 mu g ml(-1); p = 0.005) as well as those induced by previous CS protein-derived vaccines and observed in association with natural infections. A log-rank comparison of time to falciparum malaria revealed no differences between vaccinated and non-vaccinated subjects. Secondary analyses revealed that CS antibody levels were lower in vaccinee malaria cases than in non-cases, 3 and 5 months after the third dose of vaccine (p = 0.06 and p = 0.014, respectively). Because antibody levels had fallen substantially before peak malaria transmission occurred the question of whether high levels of cs antibody are protective remains to be resolved. C1 ARMED FORCES RES INST MED SCI,BANGKOK,THAILAND. BIOMED RES INST,ROCKVILLE,MD. STAT COLLABORAT,WASHINGTON,DC. SWISS SERUM & VACCINE INST,CH-3001 BERN,SWITZERLAND. SMITHKLINE BEECHAM PHARMACEUT,KING OF PRUSSIA,PA. RP BROWN, AE (reprint author), WALTER REED ARMY MED CTR,WALTER REED ARMY INST RES,DIV RETROVIROL,WASHINGTON,DC 20307, USA. NR 28 TC 37 Z9 38 U1 0 U2 1 PU BUTTERWORTH-HEINEMANN LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB SN 0264-410X J9 VACCINE JI Vaccine PD FEB PY 1994 VL 12 IS 2 BP 102 EP 108 DI 10.1016/0264-410X(94)90046-9 PG 7 WC Immunology; Medicine, Research & Experimental SC Immunology; Research & Experimental Medicine GA MP253 UT WOS:A1994MP25300002 PM 8147091 ER PT J AU LIANG, MF LI, DX XIAO, SY HANG, CS ROSSI, CA SCHMALJOHN, CS AF LIANG, MF LI, DX XIAO, SY HANG, CS ROSSI, CA SCHMALJOHN, CS TI ANTIGENIC AND MOLECULAR CHARACTERIZATION OF HANTAVIRUS ISOLATES FROM CHINA SO VIRUS RESEARCH LA English DT Article DE HANTAAN VIRUS; HANTAVIRUS; BUNYAVIRIDAE; HEMORRHAGIC FEVER WITH RENAL SYNDROME ID NEPHROPATHIA-EPIDEMICA VIRUS; NUCLEOTIDE-SEQUENCE ANALYSIS; POLYMERASE CHAIN-REACTION; KOREAN HEMORRHAGIC-FEVER; RENAL SYNDROME VIRUSES; HANTAAN VIRUS; CODING STRATEGY; GENOME SEGMENT; SYNDROME HFRS; RNA SEGMENT AB Hemorrhagic fever with renal syndrome (HFRS) is caused by certain viruses in the genus Hantavirus, family Bunyaviridae, and is a major public health problem in China. By using molecular and serological tests, we characterized 15 hantaviruses isolated either from patients with HFRS or from rodents captured in endemic areas of China. By cross plaque-reduction neutralization tests performed with rabbit immune sera, we identified two serologically distinct groups of viruses, comprised of those related to Hantaan virus, and those related to Seoul virus. To study the genetic relationships among these viruses, we amplified a 330 base pair region of the medium (M) genome segment of each isolate by reverse transcription and polymerase chain reaction (PCR) and compared the nucleotide sequences to those of other, well-characterized hantaviruses. In addition, we PCR-amplified and analyzed the entire coding region of the small (S) genome segment of each isolate by restriction enzyme digestion with a battery of enzymes. The results of our genetic analyses of both the M and S segments of these isolates confirmed our serological data, indicating that Hantaan and Seoul viruses co-circulate in endemic disease regions of China. We constructed a phylogenetic tree based on multiple alignment of the partial M segment sequences. The resulting dendrogram distinguished three genetic subtypes of Hantaan viruses and one type of Seoul virus. C1 USA,MED RES INST INFECT DIS,DIV VIROL,FREDERICK,MD 21702. USA,MED RES INST INFECT DIS,DIV APPL RES,FREDERICK,MD 21702. RI Xiao, Shu-Yuan/E-2215-2012 NR 42 TC 39 Z9 64 U1 0 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0168-1702 J9 VIRUS RES JI Virus Res. PD FEB PY 1994 VL 31 IS 2 BP 219 EP 233 PG 15 WC Virology SC Virology GA MV709 UT WOS:A1994MV70900005 PM 7909976 ER PT J AU CROSS, AS AF CROSS, AS TI INDUCING AN ABSCESS SO LANCET LA English DT Editorial Material ID POLYSACCHARIDE; BACTEROIDES RP CROSS, AS (reprint author), WALTER REED ARMY INST RES,DEPT SOCIOL,WASHINGTON,DC 20307, USA. NR 10 TC 7 Z9 7 U1 0 U2 0 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD JAN 29 PY 1994 VL 343 IS 8892 BP 248 EP 249 DI 10.1016/S0140-6736(94)91106-1 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA MT440 UT WOS:A1994MT44000004 PM 7905090 ER PT J AU SELCO, JI BROOKS, T CHANG, M TRIEU, MT MCDONALD, JK MCMANUS, SP AF SELCO, JI BROOKS, T CHANG, M TRIEU, MT MCDONALD, JK MCMANUS, SP TI SOLUTION PHOTOCHEMISTRY OF AZULENE SO JOURNAL OF ORGANIC CHEMISTRY LA English DT Article ID ELECTRONIC-SPECTRA; NAPHTHALENE; ISOMERIZATION; FLUORESCENCE; DEACTIVATION; MOLECULES AB Photochemical reactivity has been observed in solution-phase azulene. Experiments are described which confirm photoinduced deuteration, chlorination, and polymerization. The threshold for the observed chemistry is at the origin of S-2 which is at 27956 +/- 8 cm(-1) (357.7 +/- 0.1 nm) in chloroform. Only one photon is required to induce the observed chlorine substitution reactions. Although no naphthalene is formed, this chemical channel appears to be the equivalent of a thermal reaction, with the substitutions taking place at the two equivalent positions: on the small ring of azulene. The mechanism of these reactions is bimolecular in nature. Chlorination provides a complex mixture of products in most cases; however, deuteration proceeds cleanly giving only 1,3-d(2)-azulene. C1 USA,MISSILE COMMAND,CTR RES DEV & ENGN,WEAPONS SCI DIRECTORATE,AMSMI,RD,WS,CM,REDSTONE ARSENAL,AL 35898. UNIV REDLANDS,DEPT CHEM,REDLANDS,CA 92373. UNIV ALABAMA,DEPT CHEM,HUNTSVILLE,AL 35899. NR 43 TC 12 Z9 12 U1 3 U2 6 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0022-3263 J9 J ORG CHEM JI J. Org. Chem. PD JAN 28 PY 1994 VL 59 IS 2 BP 429 EP 433 DI 10.1021/jo00081a024 PG 5 WC Chemistry, Organic SC Chemistry GA MV010 UT WOS:A1994MV01000024 ER PT J AU WILSON, BW KAWAKAMI, TG CONE, N HENDERSON, JD ROSENBLATT, LS GOLDMAN, M DACRE, JC AF WILSON, BW KAWAKAMI, TG CONE, N HENDERSON, JD ROSENBLATT, LS GOLDMAN, M DACRE, JC TI GENOTOXICITY OF THE PHOSPHORAMIDATE AGENT TABUN (GA) SO TOXICOLOGY LA English DT Article DE TABUN; AGENT GA; PHOSPHOROAMIDOCYANIDIC ACID, DIMETHYL-, ETHYL ESTER; DIMETHYL-, ETHYL ESTER; GENOTOXICITY; MUTAGENIC ASSAYS ID SISTER-CHROMATID EXCHANGE; REQUIRING METABOLIC ACTIVATION; MOUSE LYMPHOMA-CELLS; MUTAGEN CARCINOGENS; PESTICIDES; ASSAY; INVIVO; HEPATOCYTES; CULTURES; LOCUS AB Five mutagenicity tests were performed on Agent GA (Tabun, phosphoramidocyanidic acid, dimethyl-, ethyl ester) as part of a program to demilitarize chemical warfare agents. GA was mutagenic in Salmonella spp. assays with S-9 and it was a direct-acting mutagen to mouse lymphoma cells. GA did not promote unscheduled DNA synthesis in rat hepatocytes; it induced sister chromatid exchanges in mouse cells in vitro but not in vivo. The conclusion that GA is a weakly acting mutagen is supported by the fact that it was mutagenic in only three of the five assays, and that increases in mutagenicity were often less than 2-fold the controls and occurred near toxic levels. C1 UNIV CALIF DAVIS,DEPT ENVIRONM TOXICOL,DAVIS,CA 95616. UNIV CALIF DAVIS,INST TOXICOL & ENVIRONM HLTH,DAVIS,CA 95616. USA,BIOMED RES & DEV LAB,FT DETRICK,MD 21702. RP WILSON, BW (reprint author), UNIV CALIF DAVIS,DEPT AVIAN SCI,DAVIS,CA 95616, USA. NR 39 TC 4 Z9 4 U1 0 U2 2 PU ELSEVIER SCI IRELAND LTD PI CLARE PA CUSTOMER RELATIONS MANAGER, BAY 15, SHANNON INDUSTRIAL ESTATE CO, CLARE, IRELAND SN 0300-483X J9 TOXICOLOGY JI Toxicology PD JAN 26 PY 1994 VL 86 IS 1-2 BP 1 EP 12 DI 10.1016/0300-483X(94)90049-3 PG 12 WC Pharmacology & Pharmacy; Toxicology SC Pharmacology & Pharmacy; Toxicology GA NB252 UT WOS:A1994NB25200001 PM 8134917 ER PT J AU FOLKES, PA AF FOLKES, PA TI FLUCTUATING DEEP-LEVEL TRAP OCCUPANCY MODEL FOR HOOGES 1/F NOISE PARAMETER FOR SEMICONDUCTOR RESISTORS SO APPLIED PHYSICS LETTERS LA English DT Article ID FIELD-EFFECT TRANSISTORS AB A theoretical expression for Hooge's 1/f noise parameter alpha, for a Schottky barrier field-effect transistor, which has been biased at a small drain-source voltage (a gate-controlled semiconductor resistor), has been derived. The theory is based on the fluctuating occupancy of deep level traps in the depletion region. The theory explains the large variations in the observed values of Hooge's parameter since the derived expression shows that a varies approximately as n(-7/2), where n is the electron density, and that alpha is sensitive to the trap concentration, the gate (or semiconductor surface) potential, the thickness of the semiconductor conducting layer, and the low-field electron mobility-depletion depth profile. Detailed experimental characterization of a semiconductor resistor has been carried out resulting in the accurate determination of alpha over a range of the applied gate voltage, V-g. We obtain excellent agreement between the theoretical and experimental dependence of a on V-g. RP FOLKES, PA (reprint author), USA,RES LAB,FT MONMOUTH,NJ 07703, USA. NR 10 TC 1 Z9 1 U1 0 U2 1 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD JAN 24 PY 1994 VL 64 IS 4 BP 487 EP 489 DI 10.1063/1.111138 PG 3 WC Physics, Applied SC Physics GA MT009 UT WOS:A1994MT00900032 ER PT J AU ABBOTT, KC SANDERS, LR BAKRIS, GJ AF ABBOTT, KC SANDERS, LR BAKRIS, GJ TI MICROALBUMINURIA IN NON-INSULIN-DEPENDENT DIABETES-MELLITUS - IMPLICATIONS FOR RENAL SURVIVAL SO ARCHIVES OF INTERNAL MEDICINE LA English DT Review ID URINARY ALBUMIN EXCRETION; ACID ETHYL-ESTER; BLOOD-PRESSURE; ABNORMAL ALBUMINURIA; GLOMERULAR STRUCTURE; SODIUM RESTRICTION; METABOLIC CONTROL; GLYCEMIC CONTROL; NATURAL-HISTORY; DIETARY-PROTEIN AB Microvascular and macrovascular disease cause considerable mortality and morbidity both among patients with non-insulin-dependent diabetes mellitus and those with insulin-dependent diabetes mellitus. Furthermore, non-insulin-dependent and insulin-dependent diabetes mellitus overlap in their pathogenesis as well as short- and long-term complications. In the diabetic patient, genetic susceptibility as well as other factors, ie, microalbuminuria, hypertension, high protein intake, blood glucose control, etc, ultimately culminate in a diffuse disease process, eg, diabetic vascular and/or renal disease. Early predictors of susceptibility for development of renal disease in diabetic subjects would help focus our treatment strategies. The role of microalbuminuria as a prognostic marker for the major complications of insulin-dependent diabetes mellitus has been previously reviewed. We reviewed the role of microalbuminuria as a prognostic marker for progression of diabetic renal disease in subjects with non-insulin-dependent diabetes mellitus. We examined treatment strategies to lower microalbuminuria and its associated impact on disease progression. C1 RUSH MED COLL,RUSH PRESBYTERIAN ST LUKES MED CTR,DEPT PREVENT MED,CHICAGO,IL 60612. RUSH MED COLL,DEPT INTERNAL MED,CHICAGO,IL 60612. RUSH MED COLL,DIV NEPHROL,CHICAGO,IL 60612. RUSH MED COLL,DIV ENDOCRINOL,CHICAGO,IL 60612. BROOKE ARMY MED CTR,DEPT MED,DIV NEPHROL,FT SAM HOUSTON,TX 78234. UNIV TEXAS,HLTH SCI CTR,DEPT MED,DIV NEPHROL,SAN ANTONIO,TX 78284. OI Abbott, Kevin/0000-0003-2111-7112 NR 109 TC 20 Z9 20 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0003-9926 J9 ARCH INTERN MED JI Arch. Intern. Med. PD JAN 24 PY 1994 VL 154 IS 2 BP 146 EP 153 DI 10.1001/archinte.154.2.146 PG 8 WC Medicine, General & Internal SC General & Internal Medicine GA MR236 UT WOS:A1994MR23600004 PM 8285809 ER PT J AU XIE, JG RUEKGAUER, TE GU, J ARMSTRONG, RL PINNICK, RG AF XIE, JG RUEKGAUER, TE GU, J ARMSTRONG, RL PINNICK, RG TI RANDOM OCCURRENCE OF STIMULATED RAMAN-SCATTERING EMISSION FROM LIQUID WATER MICRODROPLETS SO APPLIED OPTICS LA English DT Article ID MICROMETER-SIZED DROPLETS; RESONANCES; SPECTRA; TIME AB Stimulated Raman scattering (SRS) spectra from micrometer-sized water droplets have been obtained in the range 2100 < DELTAnu < 5100 cm-1. A number of Raman bands have been individually identified (to our knowledge, for the first time), corresponding to fundamental OH- and OD-stretching vibrations and to vibrations of hydrogen-bonded molecular complexes. All bands exhibit the intense morphology-dependent resonance features that are characteristic of SRS emission from microdroplets. SRS emission is apparently random from all bands; however, the frequency of occurrence varies widely, from bands where emission is seen on practically every laser shot to bands where emission is seen only once in > 10(4) laser shots. Possible causes of these noteworthy emission features are discussed, including the difficulty of coupling weak spontaneous Raman emission to both the intense pump beam and the morphology-dependent resonances within the droplet. C1 NEW MEXICO STATE UNIV, DEPT PHYS, LAS CRUCES, NM 88003 USA. RP XIE, JG (reprint author), USA, RES LAB, WHITE SANDS MISSILE RANGE, NM 88002 USA. NR 23 TC 13 Z9 13 U1 0 U2 0 PU OPTICAL SOC AMER PI WASHINGTON PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA SN 1559-128X EI 2155-3165 J9 APPL OPTICS JI Appl. Optics PD JAN 20 PY 1994 VL 33 IS 3 BP 368 EP 372 PG 5 WC Optics SC Optics GA MX856 UT WOS:A1994MX85600009 PM 20862028 ER PT J AU KHALED, EEM HILL, SC BARBER, PW AF KHALED, EEM HILL, SC BARBER, PW TI INTERNAL ELECTRIC ENERGY IN A SPHERICAL-PARTICLE ILLUMINATED WITH A PLANE-WAVE OR OFF-AXIS GAUSSIAN-BEAM SO APPLIED OPTICS LA English DT Article ID STIMULATED RAMAN-SCATTERING; MORPHOLOGY-DEPENDENT RESONANCES; FOCUSED LASER-BEAM; LOCALIZED APPROXIMATION; ELECTROMAGNETIC-FIELD; DIELECTRIC SPHERES; LIGHT-SCATTERING; LIQUID DROPLETS; MICRODROPLETS; GENERATION AB The electric energy in a lossless or lossy spherical particle that is illuminated with a plane wave or a Gaussian beam is investigated. The analysis uses a combination of the plane-wave spectrum technique and the T-matrix method. Expressions for the electric energy in any mode all well as the total electric energy inside the particle are given. The amount of energy coupling into the particle for different beam illuminations is also investigated. The high-Q (low-order) resonant modes can dominate the electric energy inside a spherical particle many linewidths away from the resonance location, particularly if the beam is focused at the droplet edge or outside the droplet. If the sphere is lossy, low-order modes can still dominate the electric energy if the beam is focused far enough outside the sphere. As the absorption coefficient of the particle increases, the energy in a high-Q mode decreases much faster at the resonance frequency than it does at near or off-resonance frequencies. The effects of the absorption on the dominance of the internal fields by a high-Q mode decreases as the beam is shifted farther away from the particle. As the beam is shifted farther away from the particle the fraction of the incident energy coupled into the sphere at resonance first increases and then decreases. Although the coupled energy decreases as the beam is shifted farther from the sphere, most of that energy is in the lowest-order mode. C1 CLARKSON UNIV, DEPT ELECT & COMP ENGN, POTSDAM, NY 13699 USA. DESERT RES INST, CTR ATMOSPHER SCI, RENO, NV 89506 USA. USA, ATMOSPHER SCI LAB, WHITE SANDS MISSILE RANGE, NM 88002 USA. NEW MEXICO STATE UNIV, DEPT ELECT & COMP ENGN, LAS CRUCES, NM 88003 USA. NR 29 TC 30 Z9 34 U1 0 U2 3 PU OPTICAL SOC AMER PI WASHINGTON PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA SN 0003-6935 J9 APPL OPTICS JI Appl. Optics PD JAN 20 PY 1994 VL 33 IS 3 BP 524 EP 532 PG 9 WC Optics SC Optics GA MX856 UT WOS:A1994MX85600025 PM 20862044 ER PT J AU CARANTO, GR WAIBEL, KH ASHER, JM LARRISON, RW BRECHT, KM SCHUTZ, MB RAVEH, L ASHANI, Y WOLFE, AD MAXWELL, DM DOCTOR, BP AF CARANTO, GR WAIBEL, KH ASHER, JM LARRISON, RW BRECHT, KM SCHUTZ, MB RAVEH, L ASHANI, Y WOLFE, AD MAXWELL, DM DOCTOR, BP TI AMPLIFICATION OF THE EFFECTIVENESS OF ACETYLCHOLINESTERASE FOR DETOXIFICATION OF ORGANOPHOSPHORUS COMPOUNDS BY BIS-QUATERNARY OXIMES SO BIOCHEMICAL PHARMACOLOGY LA English DT Article ID PRETREATMENT DRUGS; RHESUS-MONKEYS; NERVE AGENTS; MICE; PROPHYLAXIS; PROTECTION; SOMAN; TOXICITY; BUTYRYLCHOLINESTERASE; ANTIDOTES AB Pretreatment of rhesus monkeys with fetal bovine serum acetylcholinesterase (FBS AChE) provides complete protection against 5 LD(50) of organophosphate (OF) without any signs of toxicity or performance decrements as measured by serial probe recognition tests or primate equilibrium platform performance (Maxwell ct al., Toxicol Appl Pharmacol 115: 44-49, 1992; Wolfe et al., Toxicol Appl Pharmacol 117: 189-193, 1992). Although such use of enzyme as a single pretreatment drug for OP toxicity is sufficient to provide complete protection, a relatively large (stoichiometric) amount of enzyme was required in vivo to neutralize OP. To improve the efficacy of cholinesterases as pretreatment drugs, we have developed an approach in which the catalytic activity of OF-inhibited FBS AChE was rapidly and continuously restored, thus detoxifying the OP and minimizing enzyme aging by having sufficient amounts of appropriate oxime present. The efficacy of FBS AChE to detoxify several OPs was amplified by addition of bis-quaternary oximes, particularly 1-(2-hydroxyiminomethyl-1-pyridinium) 1-(4-carboxyaminopyridinium)-dimethyl ether hydrochloride (HI-6). When mice were pretreated with sufficient amounts of FBS AChE and HI-6 and challenged with repeated doses of O-isopropyl methylphosphonofluoridate (sarin), the OP was continuously detoxified so long as the molar concentration of the sarin dose was less than the molar concentration of AChE in circulation. The in vitro experiments showed that the stoichiometry of sarin:FBS AChE was higher than 3200:1 and in vivo stoichiometry with mice was as high as 57:1. Addition of HI-6 to FBS AChE as a pretreatment drug amplified the efficacy of enzyme as a scavenger of nerve agents. C1 WALTER REED ARMY INST RES,DIV BIOCHEM,WASHINGTON,DC 20307. USA,MED RES INST CHEM DEF,DIV PHARMACOL,ABERDEEN PROVING GROUND,MD 21010. USA,MED RES INST CHEM DEF,DIV DRUG ASSESSMENT,ABERDEEN PROVING GROUND,MD 21010. ISRAEL INST BIOL RES,NESS ZIONA,ISRAEL. NR 31 TC 36 Z9 36 U1 0 U2 6 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0006-2952 J9 BIOCHEM PHARMACOL JI Biochem. Pharmacol. PD JAN 20 PY 1994 VL 47 IS 2 BP 347 EP 357 DI 10.1016/0006-2952(94)90026-4 PG 11 WC Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA MU887 UT WOS:A1994MU88700026 PM 8304979 ER PT J AU SIEGEL, SE AF SIEGEL, SE TI WHERE DO OBITUARY LISTINGS COME FROM - PUTTING THE MATTER TO REST SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Letter RP SIEGEL, SE (reprint author), WALTER REED ARMY MED CTR,WASHINGTON,DC 20307, USA. NR 2 TC 0 Z9 0 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD JAN 19 PY 1994 VL 271 IS 3 BP 194 EP 195 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA MQ645 UT WOS:A1994MQ64500024 ER PT J AU BJORNSON, DC HINER, WO POTYK, RP AF BJORNSON, DC HINER, WO POTYK, RP TI PHARMACEUTICAL CARE AND INPATIENT OUTCOMES SO AMERICAN JOURNAL OF HOSPITAL PHARMACY LA English DT Letter C1 LOWER BUCKS HOSP,BRISTOL,PA 19007. USA,DEPT MED,CTR PHARMACOECON,FT SAM HOUSTON,TX 78234. RP BJORNSON, DC (reprint author), DRAKE UNIV,COLL PHARM & HLTH SCI,28TH & FOREST,DES MOINES,IA 50311, USA. NR 4 TC 0 Z9 0 U1 0 U2 1 PU AMER SOC HEALTH-SYSTEM PHARMACISTS PI BETHESDA PA 7272 WISCONSIN AVE, BETHESDA, MD 20814 SN 0002-9289 J9 AM J HOSP PHARM JI Am. J. Hosp. Pharm. PD JAN 15 PY 1994 VL 51 IS 2 BP 241 EP 242 PG 2 WC Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA MU538 UT WOS:A1994MU53800025 ER PT J AU PARK, RC AF PARK, RC TI AGE - IS IT A RISK FACTOR IN OVARIAN-CANCER SO CANCER LA English DT Editorial Material RP PARK, RC (reprint author), UNIFORMED SERV UNIV HLTH SCI,WALTER REED ARMY MED CTR,DEPT OBSTET & GYNECOL,WASHINGTON,DC 20307, USA. NR 5 TC 3 Z9 3 U1 0 U2 1 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0008-543X J9 CANCER JI Cancer PD JAN 15 PY 1994 VL 73 IS 2 BP 245 EP 246 DI 10.1002/1097-0142(19940115)73:2<245::AID-CNCR2820730202>3.0.CO;2-G PG 2 WC Oncology SC Oncology GA MR381 UT WOS:A1994MR38100001 PM 8293383 ER PT J AU MOUL, JW SCHANNE, FJ THOMPSON, IM FRAZIER, HA PERETSMAN, SA WETTLAUFER, JN ROZANSKI, TA STACK, RS KREDER, KJ HOFFMAN, KJ AF MOUL, JW SCHANNE, FJ THOMPSON, IM FRAZIER, HA PERETSMAN, SA WETTLAUFER, JN ROZANSKI, TA STACK, RS KREDER, KJ HOFFMAN, KJ TI TESTICULAR CANCER IN BLACKS - A MULTICENTER EXPERIENCE SO CANCER LA English DT Article DE TESTICULAR; CANCER; BLACK RACE; SEMINOMA; NONSEMINOMA ID UNITED-STATES; SEMINOMA; SURVIVAL; TUMORS; WHITES; IMPACT AB Background. The rarity of testis tumor in black patients has made the study of a large series difficult. Much of the epidemiologic and clinical information regarding this neoplasm in this population is in dispute, including data on incidence, prognosis, histologic distribution, age and stage at presentation, and side distribution. Methods. A retrospective review of 66 blacks with testicular tumors from seven military medical centers was performed. Results. Similar results were found for blacks with testis tumor to those of the general testis cancer population regarding prognosis, side distribution, and age of onset for nonseminoma and interstitial tumors. There is a slight increase in the expected number of interstitial tumors in blacks, but the distribution between seminoma and nonseminoma is similar to the general population. The mean age of presentation for seminoma in blacks was younger than that of the general testis cancer population. For testis tumor treated at the same institution, there was an increased delay of diagnosis in blacks compared with whites. The number of new cases of testicular cancer between 1979 and 1991 at one major center was increased for whites but not for blacks. The availability of cisplatin-based combination chemotherapy has resulted in an improved prognosis for blacks, as has already been demonstrated for white populations. Conclusions. Testis tumor in blacks behaves similarly to testis tumor in the general population except that in blacks there are more interstitial tumors and the mean age of presentation for seminoma is younger. Further, there is an increased delay in diagnosis for blacks compared with whites, but the incidence of this tumor in this population does not appear to be increasing. Cisplatin-based chemotherapy has significantly improved survival in this population. C1 WALTER REED ARMY MED CTR, UROL SERV, WASHINGTON, DC USA. BROOKE ARMY MED CTR, UROL SERV, SAN ANTONIO, TX USA. NATL NAVAL MED CTR, UROL SERV, BETHESDA, MD USA. WILFORD HALL USAF MED CTR, UROL SERV, SAN ANTONIO, TX USA. MADIGAN ARMY MED CTR, UROL SERV, TACOMA, WA USA. TRIPLER ARMY MED CTR, UROL SERV, HONOLULU, HI USA. FITZSIMONS ARMY MED CTR, UROL SERV, AURORA, CO USA. UNIFORMED SERV UNIV HLTH SCI, DEPT PREVENT MED & BIOMETR, BETHESDA, MD USA. RP MOUL, JW (reprint author), USUHS, DEPT SURG, 4301 JONES BRIDGE RD, BETHESDA, MD 20814 USA. NR 37 TC 27 Z9 27 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0008-543X J9 CANCER JI Cancer PD JAN 15 PY 1994 VL 73 IS 2 BP 388 EP 393 DI 10.1002/1097-0142(19940115)73:2<388::AID-CNCR2820730225>3.0.CO;2-Q PG 6 WC Oncology SC Oncology GA MR381 UT WOS:A1994MR38100024 PM 8293405 ER PT J AU MOUL, JW MCCARTHY, WF FERNANDEZ, EB SESTERHENN, IA AF MOUL, JW MCCARTHY, WF FERNANDEZ, EB SESTERHENN, IA TI PERCENTAGE OF EMBRYONAL CARCINOMA AND OF VASCULAR INVASION PREDICTS PATHOLOGICAL STAGE IN CLINICAL STAGE-I NONSEMINOMATOUS TESTICULAR CANCER SO CANCER RESEARCH LA English DT Note ID HISTOPATHOLOGY; INTERGROUP AB We analyzed 92 clinical stage I nonseminomatous testicular germ cell tumors for primary tumor histological factors that would distinguish true pathological stage I disease (N = 54) from those patients who harbored occult disease and actually were later found to have pathological stage II disease (N = 38). Primary tumor pathological material was analyzed for vascular invasion, lymphatic invasion, tunical invasion, and quantitative determination of percentage of the primary tumor composed of embryonal carcinoma, yolk sac carcinoma, teratoma, and seminoma. Univariate logistic regression analyses revealed that vascular invasion (P = 0.0001), percentage of embryonal carcinoma (P = 0.0001), lymphatic invasion (P = 0.0001), and tunical invasion (P = 0.0013) were higher in pathological stage II and that percentage of teratoma (P = 0.0001) and of yolk sac carcinoma (P = 0.0174) were higher in stage I. Percentage of seminoma was not significant. Individually, these parameters were able to correctly predict occult disease 66.3 to 80.4% of the time. In multivariate logistic regression analysis, only vascular invasion and percentage of embryonal carcinoma remained significant, and a model using these two variables was able to correctly predict stage 85.9% of the time. Vascular invasion and determination of percentage of embryonal carcinoma should be assessed for all clinical stage I nonseminomatous germ cell tumor patients and the model presented herein can be used clinically to predict the likelihood of occult disease and dictate therapy. C1 WALTER REED ARMY MED CTR,DEPT SURG,UROL SERV,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,DEPT CLIN INVEST,WASHINGTON,DC 20307. ARMED FORCES INST PATHOL,DEPT GENITOURINARY PATHOL,WASHINGTON,DC 20306. RP MOUL, JW (reprint author), UNIFORMED SERV UNIV HLTH SCI,DEPT SURG,BETHESDA,MD 20814, USA. NR 12 TC 88 Z9 90 U1 0 U2 0 PU AMER ASSOC CANCER RESEARCH PI PHILADELPHIA PA PUBLIC LEDGER BLDG, SUITE 816, 150 S. INDEPENDENCE MALL W., PHILADELPHIA, PA 19106 SN 0008-5472 J9 CANCER RES JI Cancer Res. PD JAN 15 PY 1994 VL 54 IS 2 BP 362 EP 364 PG 3 WC Oncology SC Oncology GA MR217 UT WOS:A1994MR21700010 PM 8275469 ER PT J AU BRADSHAW, JL LEAVITT, RP PHAM, JT TOWNER, FJ AF BRADSHAW, JL LEAVITT, RP PHAM, JT TOWNER, FJ TI INTERACTION OF A STRONGLY COUPLED SUPERLATTICE WITH TERMINATING QUANTUM-WELLS SO PHYSICAL REVIEW B LA English DT Article ID ENVELOPE-FUNCTION APPROXIMATION; EMPIRICAL 2-BAND MODEL; MOLECULAR-BEAM EPITAXY; LATTICE BAND-STRUCTURE; EXCITON STARK LADDER; ELECTRIC-FIELD; OPTICAL-ABSORPTION; STATES; DEPENDENCE; NONPARABOLICITY AB Quantum wells are used to terminate the periodicity of a tightly coupled superlattice. When an electric field is applied, the quantum veils can interact with either the conduction or valence bands of the superlattice, depending upon the direction of the field, and whether the quantum wells are right-end or left-end terminations of the superlattice. We monitor the quantum-well-superlattice interactions with photocurrent spectroscopy at 77 K. Quantitative analysis of the conduction- or valence-band quantum-well-superlattice interactions depends sensitively on the band-offset ratio. The conduction-band and yalence-band offsets are determined separately and used to test the validity and utility of an empirical two-band effective-mass model for analysis of complex heterostructures with both thick (similar to 100 Angstrom) and thin (similar to 20 Angstrom) layers. C1 MARTIN MARIETTA CORP,BALTIMORE,MD 21227. RP BRADSHAW, JL (reprint author), USA,RES LAB,2800 POWDER MILL RD,ADELPHI,MD 20783, USA. RI Bradshaw, John/E-8330-2011 NR 43 TC 6 Z9 6 U1 0 U2 1 PU AMERICAN PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0163-1829 J9 PHYS REV B JI Phys. Rev. B PD JAN 15 PY 1994 VL 49 IS 3 BP 1882 EP 1892 DI 10.1103/PhysRevB.49.1882 PG 11 WC Physics, Condensed Matter SC Physics GA MW694 UT WOS:A1994MW69400044 ER PT J AU LEAVITT, RP AF LEAVITT, RP TI CONNECTION RULES FOR ENVELOPE FUNCTIONS AT SEMICONDUCTOR-HETEROSTRUCTURE INTERFACES - COMMENT SO PHYSICAL REVIEW B LA English DT Letter ID QUANTUM-WELLS; PARAMETERS AB It is shown that the results of calculations using a scattering-matrix approach based on empirical pseudopotentials support the use of the usual envelope-function interface connection rules at GaAs/AlAs heterojunctions, contrary to the claims of the above-cited paper, provided one uses an energy-dependent effective mass. RP LEAVITT, RP (reprint author), USA,RES LAB,2800 POWDER MILL RD,ADELPHI,MD 20783, USA. NR 8 TC 1 Z9 1 U1 0 U2 1 PU AMERICAN PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0163-1829 J9 PHYS REV B JI Phys. Rev. B PD JAN 15 PY 1994 VL 49 IS 3 BP 2212 EP 2214 DI 10.1103/PhysRevB.49.2212 PG 3 WC Physics, Condensed Matter SC Physics GA MW694 UT WOS:A1994MW69400097 ER PT J AU KUAN, CH CHOI, KK CHANG, WH FARLEY, CW CHANG, F AF KUAN, CH CHOI, KK CHANG, WH FARLEY, CW CHANG, F TI SUPPRESSION OF PARTITION NOISE IN INFRARED HOT-ELECTRON TRANSISTORS SO APPLIED PHYSICS LETTERS LA English DT Article ID PHOTOCONDUCTIVE GAIN; PHOTODETECTORS; SCATTERING AB The noise properties of hot electrons in three different infrared hot-electron transistors have been characterized. We observed that there is a reduction of generation-recombination noise after the hot electrons passed through the built-in electron energy filters. The magnitude of the reduction depends on the band structure of the filters, and can be attributed to the lack of partition noise associated with the quantum transport of the hot electrons. Based on this observation, low noise infrared hot-electron transistors can be designed using appropriate filters. C1 USA,RES LAB,EPSD,FT MONMOUTH,NJ 07703. ROCKWELL INT CORP,CTR SCI,THOUSAND OAKS,CA 91360. RP KUAN, CH (reprint author), PRINCETON UNIV,DEPT ELECT ENGN,PRINCETON,NJ 08544, USA. RI Choi, Kwong-Kit/K-9205-2013 NR 10 TC 3 Z9 3 U1 0 U2 0 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD JAN 10 PY 1994 VL 64 IS 2 BP 238 EP 240 DI 10.1063/1.111515 PG 3 WC Physics, Applied SC Physics GA MQ502 UT WOS:A1994MQ50200037 ER PT J AU GALLAGHER, MJ RUSKELL, TG CHEN, D SARID, D JENKINSON, H AF GALLAGHER, MJ RUSKELL, TG CHEN, D SARID, D JENKINSON, H TI NANOSECOND TIME-SCALE SEMICONDUCTOR PHOTOEXCITATIONS PROBED BY A SCANNING TUNNELING MICROSCOPE SO APPLIED PHYSICS LETTERS LA English DT Article ID SURFACE PHOTOVOLTAGE; SI(111)-(7X7); SPECTROSCOPY; RESOLUTION AB The high-frequency response of scanning tunneling microscopy of a semiconductor is demonstrated by using the beat frequencies of the longitudinal modes of a HeNe laser at the tunneling junction. We present a comparison of the slow and fast optical response of photoexcited charge carriers in the layered structure semiconductors n-type MoS2 and p-type WSe2 using this method. C1 USA,ARDEC,PICATINNY ARSENAL,NJ 07806. RP GALLAGHER, MJ (reprint author), UNIV ARIZONA,CTR OPT SCI,TUCSON,AZ 85721, USA. NR 11 TC 3 Z9 3 U1 1 U2 5 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD JAN 10 PY 1994 VL 64 IS 2 BP 256 EP 258 DI 10.1063/1.111521 PG 3 WC Physics, Applied SC Physics GA MQ502 UT WOS:A1994MQ50200043 ER PT J AU ESTEP, L AF ESTEP, L TI BOTTOM INFLUENCE ON THE ESTIMATION OF CHLOROPHYLL CONCENTRATION IN WATER FROM REMOTELY-SENSED DATA SO INTERNATIONAL JOURNAL OF REMOTE SENSING LA English DT Article ID COASTAL; MATTER; OCEAN AB Remote sensing algorithms that provide for the computation of chlorophyll concentration in surface waters are an important tool for the synoptic mapping of ocean optics and primary productivity. The remote sensing of chlorophyll concentration in Case 1 coastal waters (waters whose optics are primarily controlled by biologic content) could present a problem due to the presence of the bottom itself and the possible contribution of bottom reflected light to the upwelling light stream ultimately 'seen' by a remote sensor. The present work analyzes the impact on the estimation of chlorophyll concentration when a bottom is present. Multiple plots are used to exhibit and quantify the effects the presence of a bottom and bottom reflected light have on chlorophyll computation algorithms. Further, a new water type definition is proposed and threshold optical depths are calculated that provide values at which the presence of a benthic interface and bottom reflected light no longer contribute to the remotely observed upwelling light stream. RP ESTEP, L (reprint author), USA,CORPS ENGINEERS,WATERWAYS EXPT STN,VICKSBURG,MS 39180, USA. NR 13 TC 7 Z9 7 U1 0 U2 1 PU TAYLOR & FRANCIS LTD PI LONDON PA ONE GUNDPOWDER SQUARE, LONDON, ENGLAND EC4A 3DE SN 0143-1161 J9 INT J REMOTE SENS JI Int. J. Remote Sens. PD JAN 10 PY 1994 VL 15 IS 1 BP 205 EP 214 PG 10 WC Remote Sensing; Imaging Science & Photographic Technology SC Remote Sensing; Imaging Science & Photographic Technology GA MT596 UT WOS:A1994MT59600016 ER PT J AU ECKARDT, JR BURRIS, HA KUHN, JG BISSERY, MC KLINKALAKL, M CLARK, GM VONHOFF, DD AF ECKARDT, JR BURRIS, HA KUHN, JG BISSERY, MC KLINKALAKL, M CLARK, GM VONHOFF, DD TI ACTIVITY OF INTOPLICINE (RP60475), A NEW DNA TOPOISOMERASE-I AND TOPOISOMERASE-II INHIBITOR, AGAINST HUMAN TUMOR COLONY-FORMING-UNITS IN-VITRO SO JOURNAL OF THE NATIONAL CANCER INSTITUTE LA English DT Article AB Background: Intoplicine (RP60475) is the most active analogue evaluated in the 7H-benzo[e]-pyrido-[4,3-b]-indole series of antineoplastic compounds. It exerts its activity through inhibition of DNA topoisomerase I and II. Purpose: This study was planned to determine plasma concentrations of intoplicine necessary for optimal clinical antitumor activity, as well as to pinpoint possible responsive tumor types that can be included in phase II clinical studies. Methods: Tumor specimens were collected from patients as part of routine clinical measures. Single-cell suspensions were prepared from freshly obtained solid tumor biopsy specimens and were exposed to intoplicine either for 1 hour or continuously. The sensitivity of these specimens to intoplicine was evaluated in a human tumor soft-agar cloning assay. Response was considered positive when the colony-forming unit count in drug-treated samples was 50% or less than the response of control tumor samples treated with saline. Results: With 1-hour exposure to intoplicine at final concentrations of 2.5 mug/mL and 10.0 mug/mL, 26% and 54% of the assessable specimens showed positive in vitro responses, respectively. With continuous exposure to intoplicine at concentrations of 0.25 mug/mL and 2.5 mug/mL, 16% and 71% of the assessable specimens showed positive responses, respectively. Activity was seen against breast (71%), non-small-cell lung (69%), and ovarian (45%) cancer colony-forming units at a intoplicine concentration of 10.0 mug/mL after 1-hour exposure. Incomplete cross-resistance with doxorubicin, cisplatin, fluorouracil, 4-hydroperoxycyclophosphamide, vinblastine, and etoposide was also observed. Conclusions: Intoplicine appears to be active in vitro against a variety of human tumors, including a subgroup of tumors insensitive in vitro to standard antineoplastic compounds. If plasma levels of 10.0 mug/mL can be achieved in subjects in ongoing clinical trials, intoplicine could have significant clinical activity. Implications: These data indicate that further investigation of intoplicine is warranted. C1 BROOKE ARMY MED CTR,HEMATOL ONCOL SERV,FT SAM HOUSTON,TX 78234. UNIV TEXAS,HLTH SCI CTR,SAN ANTONIO,TX 78284. RHONE POULENC RORER SA,VITRY,FRANCE. RP ECKARDT, JR (reprint author), CANC THERAPY & RES CTR S TEXAS,CLIN INVEST OFF,8122 DATAPOINT DR,SUITE 650,SAN ANTONIO,TX 78229, USA. NR 10 TC 11 Z9 11 U1 0 U2 0 PU NATL CANCER INSTITUTE PI BETHESDA PA 9030 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0027-8874 J9 J NATL CANCER I JI J. Natl. Cancer Inst. PD JAN 5 PY 1994 VL 86 IS 1 BP 30 EP 33 DI 10.1093/jnci/86.1.30 PG 4 WC Oncology SC Oncology GA MP650 UT WOS:A1994MP65000010 PM 8271279 ER PT J AU HARTMAN, AB VENTAKESAN, MM AF HARTMAN, AB VENTAKESAN, MM TI VARIATION IN EXPRESSION OF THE VIRULENCE PHENOTYPE IN SHIGELLA-SONNEI STRAINS - IMPLICATIONS FOR VACCINE DEVELOPMENT SO JOURNAL OF CELLULAR BIOCHEMISTRY LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DEPT ENTER INFECT,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0730-2312 J9 J CELL BIOCHEM JI J. Cell. Biochem. PD JAN 4 PY 1994 SU 18A BP 60 EP 60 PG 1 WC Biochemistry & Molecular Biology; Cell Biology SC Biochemistry & Molecular Biology; Cell Biology GA MV412 UT WOS:A1994MV41200206 ER PT J AU VANDEVERG, LL COLLINS, HH MALLETT, CP HALE, TL AF VANDEVERG, LL COLLINS, HH MALLETT, CP HALE, TL TI PULMONARY ANTIBODY AND CYTOKINE PRODUCTION IN A MOUSE LUNG SHIGELLA INFECTION MODEL SO JOURNAL OF CELLULAR BIOCHEMISTRY LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0730-2312 J9 J CELL BIOCHEM JI J. Cell. Biochem. PD JAN 4 PY 1994 SU 18A BP 63 EP 63 PG 1 WC Biochemistry & Molecular Biology; Cell Biology SC Biochemistry & Molecular Biology; Cell Biology GA MV412 UT WOS:A1994MV41200217 ER PT J AU VENKATESAN, MM AF VENKATESAN, MM TI AN INVASION PLASMID-DERIVED SHIGELLA-FLEXNERI GENE WITH HOMOLOGY TO IS629 AND TO BACTERIAL SUGAR-PHOSPHATE TRANSPORT PROTEIN SEQUENCES SO JOURNAL OF CELLULAR BIOCHEMISTRY LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DEPT ENTER INFECT,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0730-2312 J9 J CELL BIOCHEM JI J. Cell. Biochem. PD JAN 4 PY 1994 SU 18A BP 63 EP 63 PG 1 WC Biochemistry & Molecular Biology; Cell Biology SC Biochemistry & Molecular Biology; Cell Biology GA MV412 UT WOS:A1994MV41200219 ER PT J AU CHIANG, PK DOCTOR, BP BURKE, DS ZENG, GC COPELAND, RL GORDON, RK MAYERS, DL AF CHIANG, PK DOCTOR, BP BURKE, DS ZENG, GC COPELAND, RL GORDON, RK MAYERS, DL TI INDUCTION OF GENES IN CELLS BY 3-DEAZA-ADENOSINE ANALOGS AND THEIR POSSIBLE CORRELATION WITH ANTI-HIV ACTIVITIES SO JOURNAL OF CELLULAR BIOCHEMISTRY LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,WASHINGTON,DC 20307. NR 2 TC 0 Z9 0 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0730-2312 J9 J CELL BIOCHEM JI J. Cell. Biochem. PD JAN 4 PY 1994 SU 18A BP 249 EP 249 PG 1 WC Biochemistry & Molecular Biology; Cell Biology SC Biochemistry & Molecular Biology; Cell Biology GA MV412 UT WOS:A1994MV41200857 ER PT J AU ADLER, M MAXWELL, DM FILBERT, MG DESHPANDE, SS AF ADLER, M MAXWELL, DM FILBERT, MG DESHPANDE, SS TI CONTRIBUTION OF DIRECT ACTIONS OF THE OXIME HI-6 IN REVERSING SOMAN-INDUCED MUSCLE WEAKNESS IN THE RAT DIAPHRAGM SO EUROPEAN JOURNAL OF PHARMACOLOGY-ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY SECTION LA English DT Article DE HI-6([[[(4-AMINOCARBONYL)PYRIDINO]-METHOXY]METHYL]-2-[(HYDROXYIMINO)METH YL]-PYRIDINIUM DICHLORIDE); SOMAN; ACETYLCHOLINESTERASE REACTIVATION; DIAPHRAGM; RAT; MUSCLE TENSION ID ACETYLCHOLINESTERASE; REACTIVATION; INVIVO; BLOOD; INHIBITION; RECEPTOR; BINDING; THERAPY; INVITRO; AGENTS AB The actions of the bispyridinium oxime HI-6 ([[[(4-aminocarbonyl)pyridino]-methoxy]methyl]-2-[(hydroxyimino) methyl]- pyridinium dichloride) were investigated in vitro on rat phrenic nerve-hemidiaphragm preparations. Isometric twitch and tetanic tensions were elicited at 37 degrees C with supramaximal nerve stimulation at frequencies of 20 and 50 Hz. To approximate normal respiration patterns, trials consisting of 30 successive 0.55 s trains were alternated with 1.25 s rest periods. Under control conditions, the above stimulation pattern generated tensions that were well maintained at both frequencies. In contrast, a marked depression of muscle tension was observed in diaphragms removed from rats administered 339 mu g/kg soman (3 LD(50)) and tested in vitro. Addition of HI-6, 4 h after soman exposure, led to a nearly complete recovery of muscle tension at 20 Hz. At 50 Hz, muscle tensions still declined especially when trains were elicited at 1.25 and 3 s intervals. The recovery by HI-6 observed in this study appears to be mediated by mechanisms unrelated to acetylcholinesterase reactivation since no increase of enzymatic activity was detected and the effect was reversed by a brief washout in oxime-free physiological solution. The results suggest that the direct action of HI-6 may play a role in restoring soman-induced diaphragmatic failure but this effect would be significant primarily under low use conditions. C1 USA,MED RES INST CHEM DEF,BIOCHEM PHARMACOL BRANCH,ABERDEEN PROVING GROUND,MD 21010. RP ADLER, M (reprint author), USA,MED RES INST CHEM DEF,NEUROTOXICOL BRANCH,ABERDEEN PROVING GROUND,MD 21010, USA. NR 33 TC 3 Z9 3 U1 1 U2 4 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0926-6917 J9 EUR J PHARM-ENVIRON JI Eur. J. Pharmacol.-Environ. Toxicol. Pharmacol. Sect. PD JAN 3 PY 1994 VL 270 IS 1 BP 9 EP 16 DI 10.1016/0926-6917(94)90075-2 PG 8 WC Pharmacology & Pharmacy; Toxicology SC Pharmacology & Pharmacy; Toxicology GA MV102 UT WOS:A1994MV10200002 PM 8157086 ER PT B AU LENZING, EH PERLMAN, BS PASTORE, R AF LENZING, EH PERLMAN, BS PASTORE, R BE Terzuoli, A TI NEC modeling and testing of an ultra-wideband antenna for high-power operation SO 10TH ANNUAL REVIEW OF PROGRESS IN APPLIED COMPUTATIONAL ELECTROMAGNETICS, CONFERENCE PROCEEDINGS, VOL 1 LA English DT Proceedings Paper CT 10th Annual Review of Progress in Applied Computational Electromagnetics Conference CY MAR 21-26, 1994 CL MONTEREY, CA SP Appl Comp Electromagnet Soc, DOD, US DOE, IEEE, URSI, ASEE, SIAM, AMTA C1 USA,RES LAB,EPSD,FT MONMOUTH,NJ. NR 0 TC 0 Z9 0 U1 0 U2 0 PU 1994 A C E S Conference PI DAYTON PA PO BOX 3402, DAYTON, OH 45401 PY 1994 BP 376 EP 381 PG 6 WC Engineering, Electrical & Electronic SC Engineering GA BD46Z UT WOS:A1994BD46Z00046 ER PT B AU KELLY, MT RAY, DP AF KELLY, MT RAY, DP GP ENGINEERS SOC W PENNSYLVANIA TI Polymer injection of bridge deck delaminations Oahe Dam Spillway Bridge Pierre, South Dakota SO 11TH ANNUAL INTERNATIONAL BRIDGE CONFERENCE, PROCEEDINGS 1994 LA English DT Proceedings Paper CT 11th Annual International Bridge Conference and Exhibition - The Business of Bridges CY JUN 13-15, 1994 CL PITTSBURGH, PA SP Engineers Soc W Penn, Amer Concrete Inst, Amer Inst Steel Construct, Amer Inst Timber Construct, Amer Iron & Steel Inst, Amer Rd & Transportat Builders Assoc, Amer Soc Civil Engineers, Amer Soc Highway Engineers, Assoc Bridge Construct & Design, Concrete Reinforcing Steel Inst, Constructors Assoc W Penn, Natl Assoc Corros Engineers, Portland Cement Assoc, Post Tensioning Inst, Precast Prestressed Concrete Inst, Steel Struct Painting Council C1 USA,CORPS ENGINEERS,OMAHA,NE. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ENGINEERS SOC WESTERN PENNSYLVANIA PI PITTSBURGH PA 337 FOURTH AVE, PITTSBURGH, PA 15222 PY 1994 BP 95 EP 104 PG 4 WC Construction & Building Technology; Engineering, Civil SC Construction & Building Technology; Engineering GA BD74F UT WOS:A1994BD74F00016 ER PT B AU DECKER, HJ HANDSCHUH, RF ZAKRAJSEK, JJ AF DECKER, HJ HANDSCHUH, RF ZAKRAJSEK, JJ GP VIBRAT INST TI AN ENHANCEMENT TO THE NA4 GEAR VIBRATION DIAGNOSTIC PARAMETER SO 18TH ANNUAL MEETING PROCEEDINGS VIBRATION INSTITUTE LA English DT Proceedings Paper CT 18th Annual Meeting of the Vibration-Institute CY JUN 21-23, 1994 CL HERSHEY, PA SP VIBRAT INST C1 USA,RES LAB,LEWIS RES CTR,LEWIS RES CTR,PROP DIRECTORATE,CLEVELAND,OH 44035. NR 0 TC 0 Z9 0 U1 0 U2 0 PU VIBRATION INST PI CLARENDON PA 101 W 55TH ST, CLARENDON, IL 60514 PY 1994 BP 259 EP 265 PG 7 WC Engineering, Mechanical SC Engineering GA BC63G UT WOS:A1994BC63G00034 ER PT B AU BRIGGS, SJ SAVIGNON, DJ KREIN, PT KIM, MS AF BRIGGS, SJ SAVIGNON, DJ KREIN, PT KIM, MS GP IEEE, IND APPLICAT SOC TI THE EFFECTS OF NONLINEAR LOADS ON EMI/RFI FILTERS SO 1994 IEEE INDUSTRIAL AND COMMERCIAL POWER SYSTEMS TECHNICAL CONFERENCE - CONFERENCE RECORD LA English DT Proceedings Paper CT 1994 IEEE Industrial and Commercial Power Systems Technical Conference - 1994 Annual Meeting CY MAY 01-05, 1994 CL IRVINE, CA SP IEEE, IND APPLICAT SOC, IND & COMMERCIAL POWER SYST DEPT, IEEE, ORANGE CTY SECT, IEEE, ORGANE CTY JOINT CHAPTER IND APPLICAT POWER ENGN SOC C1 USA,CORPS ENGINEERS,CONSTRUCT ENGINEERS LAB,CHAMPAIGN,IL. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1877-3 PY 1994 BP 91 EP 96 PG 6 WC Engineering, Industrial; Engineering, Electrical & Electronic SC Engineering GA BA74A UT WOS:A1994BA74A00012 ER PT B AU JOHNSON, JL AF JOHNSON, JL GP IEEE TI TIME SIGNATURES OF IMAGES SO 1994 IEEE INTERNATIONAL CONFERENCE ON NEURAL NETWORKS, VOL 1-7 LA English DT Proceedings Paper CT 1994 IEEE International Conference on Neural Networks (ICNN 94) - 1st IEEE World Congress on Computational Intelligence CY JUN 26-29, 1994 CL ORLANDO, FL SP IEEE, NEURAL NETWORKS COUNCIL, IEEE, ORLANDO SECT C1 USA,MISSILE RES & DEV COMMAND,WEAP SCI DIRECTORATE,AMSMI RD WS PO,REDSTONE ARSENAL,AL 35809. NR 0 TC 1 Z9 1 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1901-X PY 1994 BP 1279 EP 1284 PG 6 WC Automation & Control Systems; Computer Science, Artificial Intelligence SC Automation & Control Systems; Computer Science GA BC54C UT WOS:A1994BC54C00238 ER PT B AU VANDERBEEK, RG WILLIAMS, LR AF VANDERBEEK, RG WILLIAMS, LR GP IEEE TI AN ANALOG HARDWARE DETECTION SCHEME FOR PASSIVE REMOTE INFRARED INTERFEROMETERS SO 1994 IEEE INTERNATIONAL CONFERENCE ON NEURAL NETWORKS, VOL 1-7 LA English DT Proceedings Paper CT 1994 IEEE International Conference on Neural Networks (ICNN 94) - 1st IEEE World Congress on Computational Intelligence CY JUN 26-29, 1994 CL ORLANDO, FL SP IEEE, NEURAL NETWORKS COUNCIL, IEEE, ORLANDO SECT C1 USA,ERDEC,SCBRD RTM,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1901-X PY 1994 BP 2131 EP 2136 PG 6 WC Automation & Control Systems; Computer Science, Artificial Intelligence SC Automation & Control Systems; Computer Science GA BC54C UT WOS:A1994BC54C00399 ER PT B AU MCCULLOUGH, CL AF MCCULLOUGH, CL GP IEEE TI NEURAL NET CONTROL VS ANTICIPATORY FUZZY CONTROL FOR A FLEXIBLE BEAM - A COMPARISON SO 1994 IEEE INTERNATIONAL CONFERENCE ON NEURAL NETWORKS, VOL 1-7 LA English DT Proceedings Paper CT 1994 IEEE International Conference on Neural Networks (ICNN 94) - 1st IEEE World Congress on Computational Intelligence CY JUN 26-29, 1994 CL ORLANDO, FL SP IEEE, NEURAL NETWORKS COUNCIL, IEEE, ORLANDO SECT C1 USA,SPACE & STRATEG DEF COMMAND,HUNTSVILLE,AL 35807. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1901-X PY 1994 BP 2351 EP 2354 PG 4 WC Automation & Control Systems; Computer Science, Artificial Intelligence SC Automation & Control Systems; Computer Science GA BC54C UT WOS:A1994BC54C00443 ER PT B AU CHEN, PF TRAN, TC AF CHEN, PF TRAN, TC GP IEEE TI HYPERSPECTRAL IMAGERY CLASSIFICATION USING A BACKPROPAGATION NEURAL NETWORK SO 1994 IEEE INTERNATIONAL CONFERENCE ON NEURAL NETWORKS, VOL 1-7 LA English DT Proceedings Paper CT 1994 IEEE International Conference on Neural Networks (ICNN 94) - 1st IEEE World Congress on Computational Intelligence CY JUN 26-29, 1994 CL ORLANDO, FL SP IEEE, NEURAL NETWORKS COUNCIL, IEEE, ORLANDO SECT C1 USA,CTR TOPOG ENGN,FT BELVOIR,VA 22060. NR 0 TC 1 Z9 1 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1901-X PY 1994 BP 2942 EP 2947 PG 6 WC Automation & Control Systems; Computer Science, Artificial Intelligence SC Automation & Control Systems; Computer Science GA BC54C UT WOS:A1994BC54C00549 ER PT B AU BELENKY, G SING, HC THOMAS, ML SHAHAM, Y BALWINSKI, S THORNE, DR REDMOND, DP BALKIN, TJ AF BELENKY, G SING, HC THOMAS, ML SHAHAM, Y BALWINSKI, S THORNE, DR REDMOND, DP BALKIN, TJ GP IEEE TI DISCRIMINATION OF RESTED FROM SLEEP-DEPRIVED EEG IN AWAKE NORMAL HUMANS BY ARTIFICIAL NEURAL NETWORK SO 1994 IEEE INTERNATIONAL CONFERENCE ON NEURAL NETWORKS, VOL 1-7 LA English DT Proceedings Paper CT 1994 IEEE International Conference on Neural Networks (ICNN 94) - 1st IEEE World Congress on Computational Intelligence CY JUN 26-29, 1994 CL ORLANDO, FL SP IEEE, NEURAL NETWORKS COUNCIL, IEEE, ORLANDO SECT C1 WALTER REED ARMY INST RES,DEPT BEHAV BIOL,DIV NEUROPSYCHIAT,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1901-X PY 1994 BP 3521 EP 3524 PG 4 WC Automation & Control Systems; Computer Science, Artificial Intelligence SC Automation & Control Systems; Computer Science GA BC54C UT WOS:A1994BC54C00656 ER PT B AU RAYBURN, DB FITZPATRICK, TM VANALBERT, SA AF RAYBURN, DB FITZPATRICK, TM VANALBERT, SA GP IEEE TI NEURAL NETWORK EVALUATION OF SLOPES FROM SEQUENTIAL VOLUME SEGMENTS OF EXPIRATORY CARBON DIOXIDE CURVES SO 1994 IEEE INTERNATIONAL CONFERENCE ON NEURAL NETWORKS, VOL 1-7 LA English DT Proceedings Paper CT 1994 IEEE International Conference on Neural Networks (ICNN 94) - 1st IEEE World Congress on Computational Intelligence CY JUN 26-29, 1994 CL ORLANDO, FL SP IEEE, NEURAL NETWORKS COUNCIL, IEEE, ORLANDO SECT C1 WALTER REED ARMY INST RES,DEPT BIOMED ENGN,DEPT RESP RES,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1901-X PY 1994 BP 3530 EP 3533 PG 4 WC Automation & Control Systems; Computer Science, Artificial Intelligence SC Automation & Control Systems; Computer Science GA BC54C UT WOS:A1994BC54C00658 ER PT B AU KELLMEYER, DL ZWAHLEN, HT AF KELLMEYER, DL ZWAHLEN, HT GP IEEE TI DETECTION OF HIGHWAY WARNING SIGNS IN NATURAL VIDEO IMAGES USING COLOR IMAGE PROCESSING AND NEURAL NETWORKS SO 1994 IEEE INTERNATIONAL CONFERENCE ON NEURAL NETWORKS, VOL 1-7 LA English DT Proceedings Paper CT 1994 IEEE International Conference on Neural Networks (ICNN 94) - 1st IEEE World Congress on Computational Intelligence CY JUN 26-29, 1994 CL ORLANDO, FL SP IEEE, NEURAL NETWORKS COUNCIL, IEEE, ORLANDO SECT C1 USA,ENVIRONM HYG AGCY,FT GEORGE G MEADE,MD 20755. NR 0 TC 1 Z9 1 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1901-X PY 1994 BP 4226 EP 4231 PG 6 WC Automation & Control Systems; Computer Science, Artificial Intelligence SC Automation & Control Systems; Computer Science GA BC54C UT WOS:A1994BC54C00782 ER PT B AU MCGINNIS, ML FERNANDEZGAUCHERAND, E AF MCGINNIS, ML FERNANDEZGAUCHERAND, E GP IEEE TI RESOURCE SCHEDULING FOR THE UNITED-STATES-ARMYS BASIC COMBAT TRAINING PROGRAM SO 1994 IEEE INTERNATIONAL CONFERENCE ON SYSTEMS, MAN, AND CYBERNETICS - HUMANS, INFORMATION AND TECHNOLOGY, VOLS 1-3 LA English DT Proceedings Paper CT 1994 IEEE International Conference on Systems, Man, and Cybernetics - Humans, Information and Technology (SMC 94) CY OCT 02-05, 1994 CL SAN ANTONIO, TX SP IEEE C1 US MIL ACAD,OPERAT RES CTR,W POINT,NY 10996. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-2129-4 PY 1994 BP 553 EP 558 PG 6 WC Automation & Control Systems; Computer Science, Artificial Intelligence; Computer Science, Cybernetics; Ergonomics SC Automation & Control Systems; Computer Science; Engineering GA BC41S UT WOS:A1994BC41S00097 ER PT B AU NEVES, K LEE, DY AF NEVES, K LEE, DY GP IEEE TI DESIGN FOR IN-PROCESS VERIFICATION (DFIPV) METHOD FOR QUALITY ASSURANCE SO 1994 IEEE INTERNATIONAL CONFERENCE ON SYSTEMS, MAN, AND CYBERNETICS - HUMANS, INFORMATION AND TECHNOLOGY, VOLS 1-3 LA English DT Proceedings Paper CT 1994 IEEE International Conference on Systems, Man, and Cybernetics - Humans, Information and Technology (SMC 94) CY OCT 02-05, 1994 CL SAN ANTONIO, TX SP IEEE C1 USA,SCI LIAISON & ADVISORY ACTIV,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-2129-4 PY 1994 BP 873 EP 878 PG 6 WC Automation & Control Systems; Computer Science, Artificial Intelligence; Computer Science, Cybernetics; Ergonomics SC Automation & Control Systems; Computer Science; Engineering GA BC41S UT WOS:A1994BC41S00152 ER PT B AU SCOZZIE, CJ TIPTON, CW DELANCEY, WM MCGARRITY, JM MCLEAN, FB AF SCOZZIE, CJ TIPTON, CW DELANCEY, WM MCGARRITY, JM MCLEAN, FB GP IEEE, ELECTRON DEVICES SOC TI HIGH-TEMPERATURE STRESSING OF SIC JFETS AT 300-DEGREES-C SO 1994 IEEE INTERNATIONAL RELIABILITY PHYSICS PROCEEDINGS - 32ND ANNUAL LA English DT Proceedings Paper CT 1994 IEEE International Reliability Physics Symposium - 32nd Annual CY APR 12-14, 1994 CL SAN JOSE, CA SP IEEE, ELECTRON DEVICES SOC, IEEE, RELIABIL SOC C1 USA,RES LAB,ADELPHI,MD 20783. NR 0 TC 4 Z9 4 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1357-7 PY 1994 BP 351 EP 358 PG 8 WC Engineering, Electrical & Electronic; Physics, Condensed Matter SC Engineering; Physics GA BA79L UT WOS:A1994BA79L00053 ER PT B AU CROISANT, WJ FEICKERT, CA MCINERNEY, MK AF CROISANT, WJ FEICKERT, CA MCINERNEY, MK GP IEEE TI A NONLINEAR ANALYTICAL PROCEDURE FOR ELECTROMAGNETIC TRANSIENTS IN FERROMAGNETIC SHIELDS SO 1994 IEEE INTERNATIONAL SYMPOSIUM ON ELECTROMAGNETIC COMPATIBILITY - COMPATIBILITY IN THE LOOP LA English DT Proceedings Paper CT 1994 IEEE International Symposium on Electromagnetic Compatibility CY AUG 22-26, 1994 CL CHICAGO, IL SP IEEE, EMC SOC C1 USA,CONSTRUCT ENGN RES LABS,CHAMPAIGN,IL 61826. NR 0 TC 3 Z9 3 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1398-4 PY 1994 BP 190 EP 195 PG 6 WC Engineering, Electrical & Electronic SC Engineering GA BB67L UT WOS:A1994BB67L00038 ER PT B AU SILIATO, JM BARONE, S SAARI, KW AF SILIATO, JM BARONE, S SAARI, KW GP IEEE TI MODELING AND SIMULATION TO SUPPORT THE DIGITIZED BATTLEFIELD SO 1994 IEEE MILCOM CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT IEEE Communications-Society 13th Military Communications Conference (MILCOM 94)/19th Annual Fort Monmouth Chapter AFCEA Symposium CY OCT 02-05, 1994 CL FT MONMOUTH, NJ SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,COMMUN ELECTR COMMAND,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1994 BP 154 EP 158 PG 5 WC Telecommunications SC Telecommunications GA BC58K UT WOS:A1994BC58K00032 ER PT B AU PROCOPIO, VJ BROCKEL, KH INSERRA, JR LOSO, FG MAJOR, PA CHANEY, KD LOCHER, RJ BARNETT, WT VIGANTS, A AF PROCOPIO, VJ BROCKEL, KH INSERRA, JR LOSO, FG MAJOR, PA CHANEY, KD LOCHER, RJ BARNETT, WT VIGANTS, A GP IEEE TI HIGH-CAPACITY TRUNK RADIO FOR TACTICAL COMMUNICATION ON THE DIGITIZED BATTLEFIELD SO 1994 IEEE MILCOM CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT IEEE Communications-Society 13th Military Communications Conference (MILCOM 94)/19th Annual Fort Monmouth Chapter AFCEA Symposium CY OCT 02-05, 1994 CL FT MONMOUTH, NJ SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,COMMUN ELECTR COMMAND,SPACE & TERR COMMUN DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1994 BP 188 EP 192 PG 5 WC Telecommunications SC Telecommunications GA BC58K UT WOS:A1994BC58K00039 ER PT B AU CHRISTOPHER, HA AF CHRISTOPHER, HA GP IEEE TI PRESENT STATUS OF ARMY BATTERY TECHNOLOGY (U) SO 1994 IEEE MILCOM CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT IEEE Communications-Society 13th Military Communications Conference (MILCOM 94)/19th Annual Fort Monmouth Chapter AFCEA Symposium CY OCT 02-05, 1994 CL FT MONMOUTH, NJ SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,RES LAB,ELECTR & POWER SOURCES DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1994 BP 199 EP 199 PG 1 WC Telecommunications SC Telecommunications GA BC58K UT WOS:A1994BC58K00042 ER PT B AU ATWATER, TB AF ATWATER, TB GP IEEE TI STATE-OF-CHARGE INDICATORS SO 1994 IEEE MILCOM CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT IEEE Communications-Society 13th Military Communications Conference (MILCOM 94)/19th Annual Fort Monmouth Chapter AFCEA Symposium CY OCT 02-05, 1994 CL FT MONMOUTH, NJ SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,RES LAB,ELECTR & POWER SOURCES DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1994 BP 203 EP 203 PG 1 WC Telecommunications SC Telecommunications GA BC58K UT WOS:A1994BC58K00046 ER PT B AU BARONE, S AF BARONE, S GP IEEE TI COMBAT NET RADIO (CNR) PROTOCOLS - A MEANS FOR BATTLEFIELD DIGITIZATION SO 1994 IEEE MILCOM CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT IEEE Communications-Society 13th Military Communications Conference (MILCOM 94)/19th Annual Fort Monmouth Chapter AFCEA Symposium CY OCT 02-05, 1994 CL FT MONMOUTH, NJ SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,COMMUN ELECTR COMMAND,COMMAND CONTROL & SYST INTEGRAT DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1994 BP 210 EP 214 PG 5 WC Telecommunications SC Telecommunications GA BC58K UT WOS:A1994BC58K00048 ER PT B AU WHEELER, TJ RICHARDSON, JD ROSENZWEIG, M CUMMINGS, D AF WHEELER, TJ RICHARDSON, JD ROSENZWEIG, M CUMMINGS, D GP IEEE TI DESIGNING A TACTICAL ATM NETWORK INTEGRATING PERFORMANCE ENGINEERING AND DESIGN SO 1994 IEEE MILCOM CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT IEEE Communications-Society 13th Military Communications Conference (MILCOM 94)/19th Annual Fort Monmouth Chapter AFCEA Symposium CY OCT 02-05, 1994 CL FT MONMOUTH, NJ SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,COMMUN ELECTR COMMAND,SPACE & TERR COMMUN DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1994 BP 215 EP 219 PG 5 WC Telecommunications SC Telecommunications GA BC58K UT WOS:A1994BC58K00049 ER PT B AU GRAFF, C HALLORAN, F LOCKHART, C AF GRAFF, C HALLORAN, F LOCKHART, C GP IEEE TI TACTICAL BATTLEFIELD ATM SO 1994 IEEE MILCOM CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT IEEE Communications-Society 13th Military Communications Conference (MILCOM 94)/19th Annual Fort Monmouth Chapter AFCEA Symposium CY OCT 02-05, 1994 CL FT MONMOUTH, NJ SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,CECOM,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1994 BP 473 EP 478 PG 6 WC Telecommunications SC Telecommunications GA BC58K UT WOS:A1994BC58K00100 ER PT B AU CHAMBERLAIN, S AF CHAMBERLAIN, S GP IEEE TI AUTOMATED INFORMATION DISTRIBUTION IN BANDWIDTH CONSTRAINED ENVIRONMENTS SO 1994 IEEE MILCOM CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT IEEE Communications-Society 13th Military Communications Conference (MILCOM 94)/19th Annual Fort Monmouth Chapter AFCEA Symposium CY OCT 02-05, 1994 CL FT MONMOUTH, NJ SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,RES LAB,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 1 Z9 1 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1994 BP 537 EP 541 PG 5 WC Telecommunications SC Telecommunications GA BC58K UT WOS:A1994BC58K00112 ER PT B AU MOSTOW, JR HARRIGAN, MJ POWELL, JC KENNEDY, LR BARNETT, WT AF MOSTOW, JR HARRIGAN, MJ POWELL, JC KENNEDY, LR BARNETT, WT GP IEEE TI NPT THE TOOL FOR PLANNING MSE NETWORKS SO 1994 IEEE MILCOM CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT IEEE Communications-Society 13th Military Communications Conference (MILCOM 94)/19th Annual Fort Monmouth Chapter AFCEA Symposium CY OCT 02-05, 1994 CL FT MONMOUTH, NJ SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,COMMUN ELECTR COMMAND,SPACE & TERR COMMUN DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1994 BP 650 EP 654 PG 5 WC Telecommunications SC Telecommunications GA BC58K UT WOS:A1994BC58K00135 ER PT B AU HARRIGAN, MJ BROCKEL, KH SUDNIKOVICH, WP WIGANTS, A BARNETT, WT CONWAYCLOUGH, S WOOD, R EDWARDS, R TOTH, J SUNSHINE, J AF HARRIGAN, MJ BROCKEL, KH SUDNIKOVICH, WP WIGANTS, A BARNETT, WT CONWAYCLOUGH, S WOOD, R EDWARDS, R TOTH, J SUNSHINE, J GP IEEE TI 24-HOUR NETWORK PERFORMANCE MANAGEMENT SYSTEM SO 1994 IEEE MILCOM CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT IEEE Communications-Society 13th Military Communications Conference (MILCOM 94)/19th Annual Fort Monmouth Chapter AFCEA Symposium CY OCT 02-05, 1994 CL FT MONMOUTH, NJ SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,COMMUN ELECTR COMMAND,SPACE & TERR COMMUN DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1994 BP 655 EP 659 PG 5 WC Telecommunications SC Telecommunications GA BC58K UT WOS:A1994BC58K00136 ER PT B AU MAYK, I AF MAYK, I GP IEEE TI INSIDE THE COMMAND AND CONTROL REFERENCE MODEL SO 1994 IEEE MILCOM CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT IEEE Communications-Society 13th Military Communications Conference (MILCOM 94)/19th Annual Fort Monmouth Chapter AFCEA Symposium CY OCT 02-05, 1994 CL FT MONMOUTH, NJ SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,CECOM,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1994 BP 843 EP 847 PG 5 WC Telecommunications SC Telecommunications GA BC58K UT WOS:A1994BC58K00173 ER PT B AU BROCKEL, KH MAJOR, PA COFIELD, DW ALVARADO, C DEALLAUME, W AF BROCKEL, KH MAJOR, PA COFIELD, DW ALVARADO, C DEALLAUME, W GP IEEE TI CECOM APPLICATION OF E3 A PROCESS FOCUSED ON OWNING THE SPECTRUM SO 1994 IEEE MILCOM CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT IEEE Communications-Society 13th Military Communications Conference (MILCOM 94)/19th Annual Fort Monmouth Chapter AFCEA Symposium CY OCT 02-05, 1994 CL FT MONMOUTH, NJ SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,COMMUN ELECTR COMMAND,SPACE & TERR COMMUN DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1994 BP 945 EP 949 PG 5 WC Telecommunications SC Telecommunications GA BC58K UT WOS:A1994BC58K00192 ER PT B AU COFIELD, DW DEALLAUME, W AF COFIELD, DW DEALLAUME, W GP IEEE TI ELECTROMAGNETIC STANDARDS FOR ARMY SYSTEMS SO 1994 IEEE MILCOM CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT IEEE Communications-Society 13th Military Communications Conference (MILCOM 94)/19th Annual Fort Monmouth Chapter AFCEA Symposium CY OCT 02-05, 1994 CL FT MONMOUTH, NJ SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,COMMUN ELECTR COMMAND,SPACE & TERR COMMUN DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 1 Z9 1 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1994 BP 950 EP 953 PG 4 WC Telecommunications SC Telecommunications GA BC58K UT WOS:A1994BC58K00193 ER PT B AU MAJOR, PA BOHN, F AF MAJOR, PA BOHN, F GP IEEE TI FREQUENCY ALLOTMENT CAPABILITY CONCEPT DEVELOPMENT STUDY SO 1994 IEEE MILCOM CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT IEEE Communications-Society 13th Military Communications Conference (MILCOM 94)/19th Annual Fort Monmouth Chapter AFCEA Symposium CY OCT 02-05, 1994 CL FT MONMOUTH, NJ SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,COMMUN ELECTR COMMAND,SPACE & TERR COMMUN DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1994 BP 954 EP 956 PG 3 WC Telecommunications SC Telecommunications GA BC58K UT WOS:A1994BC58K00194 ER PT S AU SADDOW, SE LEE, CH AF SADDOW, SE LEE, CH BE Kuno, HJ Wen, CP TI SCATTERING PARAMETER MEASUREMENTS ON AN OPTOELECTRONIC ATTENUATOR SO 1994 IEEE MTT-S INTERNATIONAL MICROWAVE SYMPOSIUM DIGEST, VOLS 1-3 SE IEEE MTT-S INTERNATIONAL MICROWAVE SYMPOSIUM DIGEST LA English DT Proceedings Paper CT 1994 IEEE MTT-S International Microwave Symposium CY MAY 23-27, 1994 CL SAN DIEGO, CA SP IEEE, MTT CHAPTER C1 ARMY RES LAB,ADELPHI,MD 20783. NR 0 TC 1 Z9 1 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 SN 0149-645X BN 0-7803-1778-5 J9 IEEE MTT-S PY 1994 BP 1383 EP 1386 DI 10.1109/MWSYM.1994.335153 PG 4 WC Engineering, Electrical & Electronic; Optics; Telecommunications SC Engineering; Optics; Telecommunications GA BB20R UT WOS:A1994BB20R00323 ER PT B AU FORCH, BE AF FORCH, BE GP IEEE TI MULTIPHOTON PHOTOCHEMISTRY AND RESONANT LASER IGNITION OF REACTIVE GASES SO 1994 IEEE NONLINEAR OPTICS: MATERIALS, FUNDAMENTALS, AND APPLICATIONS LA English DT Proceedings Paper CT 1994 IEEE Conference on Nonlinear Optics - Materials, Fundamentals, and Applications CY JUL 25-29, 1994 CL WAIKOLOA, HI SP IEEE, LASERS & ELECTRO OPT SOC, OPT SOC AMER C1 USA,RES LAB,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1473-5 PY 1994 BP 353 EP 355 PG 3 WC Optics SC Optics GA BC30X UT WOS:A1994BC30X00120 ER PT S AU BALLATO, A SMITS, JG AF BALLATO, A SMITS, JG BE Levy, M Schneider, SC McAvoy, BR TI RESONANCE AND ANTIRESONANCE OF SYMMETRIC CANTILEVERED PIEZOELECTRIC FLEXORS SO 1994 IEEE ULTRASONICS SYMPOSIUM PROCEEDINGS, VOLS 1-3 SE ULTRASONICS SYMPOSIUM LA English DT Proceedings Paper CT 1994 IEEE Ultrasonics Symposium CY NOV 01-04, 1994 CL CANNES, FRANCE SP IEEE, ULTRASON FERROELECT & FREQUENCY CONTROL SOC C1 USA,RES LAB,ELECTR & POWER SOURCES DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 SN 1051-0117 BN 0-7803-2012-3 J9 ULTRASON PY 1994 BP 599 EP 602 PG 4 WC Acoustics; Engineering, Biomedical; Engineering, Electrical & Electronic; Engineering, Mechanical; Remote Sensing; Telecommunications SC Acoustics; Engineering; Remote Sensing; Telecommunications GA BC66H UT WOS:A1994BC66H00117 ER PT S AU STEWART, JT AF STEWART, JT BE Levy, M Schneider, SC McAvoy, BR TI FINITE ELEMENT MODELING OF RESONANT MICROELECTROMECHANICAL STRUCTURES FOR SENSING APPLICATIONS SO 1994 IEEE ULTRASONICS SYMPOSIUM PROCEEDINGS, VOLS 1-3 SE ULTRASONICS SYMPOSIUM LA English DT Proceedings Paper CT 1994 IEEE Ultrasonics Symposium CY NOV 01-04, 1994 CL CANNES, FRANCE SP IEEE, ULTRASON FERROELECT & FREQUENCY CONTROL SOC C1 USA,RES LAB,ELECTR & POWER SOURCES DIRECTORATE,AMSRL EP,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 SN 1051-0117 BN 0-7803-2012-3 J9 ULTRASON PY 1994 BP 643 EP 646 PG 4 WC Acoustics; Engineering, Biomedical; Engineering, Electrical & Electronic; Engineering, Mechanical; Remote Sensing; Telecommunications SC Acoustics; Engineering; Remote Sensing; Telecommunications GA BC66H UT WOS:A1994BC66H00127 ER PT S AU BALLATO, A GUALTIERI, JG KOSINSKI, JA AF BALLATO, A GUALTIERI, JG KOSINSKI, JA BE Levy, M Schneider, SC McAvoy, BR TI PIEZOELECTRIC CHARACTERISTIC LENGTH SO 1994 IEEE ULTRASONICS SYMPOSIUM PROCEEDINGS, VOLS 1-3 SE ULTRASONICS SYMPOSIUM LA English DT Proceedings Paper CT 1994 IEEE Ultrasonics Symposium CY NOV 01-04, 1994 CL CANNES, FRANCE SP IEEE, ULTRASON FERROELECT & FREQUENCY CONTROL SOC C1 USA,RES LAB,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 1 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 SN 1051-0117 BN 0-7803-2012-3 J9 ULTRASON PY 1994 BP 745 EP 748 PG 4 WC Acoustics; Engineering, Biomedical; Engineering, Electrical & Electronic; Engineering, Mechanical; Remote Sensing; Telecommunications SC Acoustics; Engineering; Remote Sensing; Telecommunications GA BC66H UT WOS:A1994BC66H00150 ER PT B AU FISCHER, MC AF FISCHER, MC BE Tew, JD Manivannan, MS Sadowski, DA Seila, AF TI AGGREGATE LEVEL SIMULATION PROTOCOL (ALSP) MANAGING CONFEDERATION DEVELOPMENT SO 1994 WINTER SIMULATION CONFERENCE PROCEEDINGS LA English DT Proceedings Paper CT 1994 Winter Simulation Conference CY DEC 11-14, 1994 CL LAKE BUENA VISTA, FL SP AMER STAT ASSOC, ASSOC COMP MACHINERY, SPECIAL INTEREST GRP SIMULAT, IEEE, COMP SOC, IEEE, SYST MAN & CYBERNET SOC, INST IND ENGINEERS, NIST, OPERAT RES SOC AMER, INST MANAGEMENT SCI, COLL SIMULAT, SOC COMP SIMULAT, INT C1 USA,ORLANDO,FL 32826. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-2109-X PY 1994 BP 775 EP 780 PG 6 WC Computer Science, Software Engineering SC Computer Science GA BC51T UT WOS:A1994BC51T00113 ER PT B AU MCGINNIS, ML KAYS, JL SLATEN, P AF MCGINNIS, ML KAYS, JL SLATEN, P BE Tew, JD Manivannan, MS Sadowski, DA Seila, AF TI COMPUTER SIMULATION OF UNITED-STATES ARMY OFFICER PROFESSIONAL DEVELOPMENT SO 1994 WINTER SIMULATION CONFERENCE PROCEEDINGS LA English DT Proceedings Paper CT 1994 Winter Simulation Conference CY DEC 11-14, 1994 CL LAKE BUENA VISTA, FL SP AMER STAT ASSOC, ASSOC COMP MACHINERY, SPECIAL INTEREST GRP SIMULAT, IEEE, COMP SOC, IEEE, SYST MAN & CYBERNET SOC, INST IND ENGINEERS, NIST, OPERAT RES SOC AMER, INST MANAGEMENT SCI, COLL SIMULAT, SOC COMP SIMULAT, INT C1 US MIL ACAD,CTR OPERAT RES,W POINT,NY 10996. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-2109-X PY 1994 BP 813 EP 820 PG 8 WC Computer Science, Software Engineering SC Computer Science GA BC51T UT WOS:A1994BC51T00119 ER PT B AU CIONCO, RM BYERS, JH AF CIONCO, RM BYERS, JH GP AMER METEOROL SOC TI ON ANALYZING THE PRESENCE AND EFFECTS OF VEGETATIVE CANOPIES UPON THE AMBIENT SURFACE LAYER AIRFLOW SO 21ST CONFERENCE ON AGRICULTURAL AND FOREST METEOROLOGY/11TH CONFERENCE ON BIOMETEOROLOGY AND AEROBIOLOGY LA English DT Proceedings Paper CT 21st Conference on Agricultural and Forest Meteorology/11th Conference on Biometeorology and Aerobiology CY MAR 07-11, 1994 CL SAN DIEGO, CA SP AMER METEOROL SOC C1 USA,RES LAB,WHITE SANDS MISSILE RANGE,NM 88002. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108 PY 1994 BP 68 EP 71 PG 4 WC Agronomy; Ecology; Forestry; Meteorology & Atmospheric Sciences SC Agriculture; Environmental Sciences & Ecology; Forestry; Meteorology & Atmospheric Sciences GA BC95G UT WOS:A1994BC95G00019 ER PT B AU ORNDORFF, BL CIONCO, RM AF ORNDORFF, BL CIONCO, RM GP AMER METEOROL SOC TI AIRFLOW INDICES AND CHARACTERISTICS WITHIN AND ABOVE REGULAR AND IRREGULAR ROUGHNESS DOMAINS SO 21ST CONFERENCE ON AGRICULTURAL AND FOREST METEOROLOGY/11TH CONFERENCE ON BIOMETEOROLOGY AND AEROBIOLOGY LA English DT Proceedings Paper CT 21st Conference on Agricultural and Forest Meteorology/11th Conference on Biometeorology and Aerobiology CY MAR 07-11, 1994 CL SAN DIEGO, CA SP AMER METEOROL SOC C1 USA,RES LAB,WHITE SANDS MISSILE RANGE,NM 88002. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108 PY 1994 BP 72 EP 75 PG 4 WC Agronomy; Ecology; Forestry; Meteorology & Atmospheric Sciences SC Agriculture; Environmental Sciences & Ecology; Forestry; Meteorology & Atmospheric Sciences GA BC95G UT WOS:A1994BC95G00020 ER PT B AU MCLAUGHLIN, SA AF MCLAUGHLIN, SA GP AMER METEOROL SOC TI FM-CW RADAR OBSERVATIONS OF INSECTS AND BIRDS IN THE PLANETARY BOUNDARY LAYER AT WHITE SANDS MISSILE RANGE, NEW-MEXICO SO 21ST CONFERENCE ON AGRICULTURAL AND FOREST METEOROLOGY/11TH CONFERENCE ON BIOMETEOROLOGY AND AEROBIOLOGY LA English DT Proceedings Paper CT 21st Conference on Agricultural and Forest Meteorology/11th Conference on Biometeorology and Aerobiology CY MAR 07-11, 1994 CL SAN DIEGO, CA SP AMER METEOROL SOC C1 USA,RES LAB,WHITE SANDS MISSILE RANGE,NM 88002. NR 0 TC 1 Z9 1 U1 0 U2 0 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108 PY 1994 BP 419 EP 422 PG 4 WC Agronomy; Ecology; Forestry; Meteorology & Atmospheric Sciences SC Agriculture; Environmental Sciences & Ecology; Forestry; Meteorology & Atmospheric Sciences GA BC95G UT WOS:A1994BC95G00124 ER PT J AU SHANLEY, DJ GAGLIARDI, JA DAUMKOWALSKI, R AF SHANLEY, DJ GAGLIARDI, JA DAUMKOWALSKI, R TI CHOLEDOCHAL CYST COMPLICATING PREGNANCY - ANTEPARTUM DIAGNOSIS WITH MRI SO ABDOMINAL IMAGING LA English DT Article DE CHOLEDOCHAL CYST; MAGNETIC RESONANCE IMAGING; PREGNANCY AB Choledochal cyst presenting during pregnancy is a rare condition, associated with potentially life-threatening complications for both the mother and developing fetus. Clinical symptoms are nonspecific, and radiographic evaluation is complicated by the presence of the gravid uterus. The authors describe a 34-year-old pregnant female presenting in the third trimester with obstructive jaundice and a right upper quadrant mass. Multiplanar and multisequence imaging with MR established the antepartum diagnosis of choledochal cyst, avoiding the use of ionizing radiation during pregnancy. RP SHANLEY, DJ (reprint author), TRIPLER ARMY MED CTR,DEPT RADIOL,HONOLULU,HI 96859, USA. NR 12 TC 9 Z9 11 U1 0 U2 0 PU SPRINGER VERLAG PI NEW YORK PA 175 FIFTH AVE, NEW YORK, NY 10010 SN 0942-8925 J9 ABDOM IMAGING JI Abdom. Imaging PD JAN-FEB PY 1994 VL 19 IS 1 BP 61 EP 63 DI 10.1007/BF02165865 PG 3 WC Gastroenterology & Hepatology; Radiology, Nuclear Medicine & Medical Imaging SC Gastroenterology & Hepatology; Radiology, Nuclear Medicine & Medical Imaging GA MM451 UT WOS:A1994MM45100016 PM 8161908 ER PT J AU RADVANY, MG SHANLEY, DJ GAGLIARDI, JA AF RADVANY, MG SHANLEY, DJ GAGLIARDI, JA TI MAGNETIC-RESONANCE-IMAGING WITH COMPUTED-TOMOGRAPHY OF A RENAL LEIOMYOMA SO ABDOMINAL IMAGING LA English DT Article DE LEIOMYOMA; KIDNEY; MAGNETIC RESONANCE IMAGING; COMPUTED TOMOGRAPHY AB Renal leiomyoma are rare, benign tumors of the kidney. There is little information about the imaging of these tumors with modern modalities. We present a case of computed tomographic (CT) and magnetic resonance (MR) imaging of a large renal leiomyoma. RP RADVANY, MG (reprint author), TRIPLER ARMY MED CTR,DEPT RADIOL,HONOLULU,HI 96859, USA. NR 8 TC 7 Z9 10 U1 0 U2 0 PU SPRINGER VERLAG PI NEW YORK PA 175 FIFTH AVE, NEW YORK, NY 10010 SN 0942-8925 J9 ABDOM IMAGING JI Abdom. Imaging PD JAN-FEB PY 1994 VL 19 IS 1 BP 67 EP 69 DI 10.1007/BF02165867 PG 3 WC Gastroenterology & Hepatology; Radiology, Nuclear Medicine & Medical Imaging SC Gastroenterology & Hepatology; Radiology, Nuclear Medicine & Medical Imaging GA MM451 UT WOS:A1994MM45100018 PM 8161910 ER PT B AU BORNSTEIN, J HILLIS, D AF BORNSTEIN, J HILLIS, D BE Masten, MK Stockum, LA Birnhaum, MM Sevaston, GE TI MISS DISTANCE INDICATOR FOR TANK MAIN GUN SYSTEMS SO ACQUISITION, TRACKING, AND POINTING VIII SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Acquisition, Tracking, and Pointing VIII CY APR 05-08, 1994 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,RES LAB,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1525-1 J9 P SOC PHOTO-OPT INS PY 1994 VL 2221 BP 316 EP 326 DI 10.1117/12.178942 PG 11 WC Engineering, Aerospace; Optics SC Engineering; Optics GA BA83U UT WOS:A1994BA83U00029 ER PT J AU HEAVEN, R DUNCAN, M VUKELJA, SJ AF HEAVEN, R DUNCAN, M VUKELJA, SJ TI ARSENIC INTOXICATION PRESENTING WITH MACROCYTOSIS AND PERIPHERAL NEUROPATHY, WITHOUT ANEMIA SO ACTA HAEMATOLOGICA LA English DT Note DE ARSENIC INTOXICATION; MACROCYTOSIS; NEUROPATHY AB A case of arsenic intoxication associated with macrocytosis and neuropathy, without anemia, is presented. Evaluation of a 68-year-old man with a long history of peripheral neuropathy and persistent macrocytosis revealed exposure to an insecticide. Analysis of urine and hair revealed elevated levels of arsenic. A short course of d-penicillamine failed to promote urinary excretion of arsenic. Removal of the insecticide resulted in resolution of macrocytosis and slight improvement of neuropathy. This case emphasizes that arsenic intoxication should be considered in patients with macrocytosis with peripheral neuropathy, even in the absence of anemia. C1 BROOKE ARMY MED CTR,DEPT MED,HEMATOL ONCOL SERV,FT SAM HOUSTON,TX 78234. BROOKE ARMY MED CTR,DEPT MED,NEUROL SERV,FT SAM HOUSTON,TX 78234. NR 10 TC 9 Z9 9 U1 0 U2 1 PU KARGER PI BASEL PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND SN 0001-5792 J9 ACTA HAEMATOL-BASEL JI Acta Haematol. PY 1994 VL 92 IS 3 BP 142 EP 143 PG 2 WC Hematology SC Hematology GA QN386 UT WOS:A1994QN38600008 PM 7871953 ER PT J AU VUKELJA, SJ AF VUKELJA, SJ TI ERYTHROPOIETIN IN THE TREATMENT OF IRON OVERLOAD IN A PATIENT WITH HEMOLYTIC-ANEMIA AND PYRUVATE-KINASE DEFICIENCY SO ACTA HAEMATOLOGICA LA English DT Note DE ERYTHROPOIETIN; IRON OVERLOAD; PYRUVATE KINASE ID RECOMBINANT HUMAN ERYTHROPOIETIN AB Iron overload has been reported with pyruvate kinase deficiency. Erythropoietin (EPO) may lead to iron deficiency; thus, patients who are unable to be phlebotomized due to anemia may benefit from EPO as a treatment of iron overload. RP VUKELJA, SJ (reprint author), BROOKE ARMY MED CTR,DEPT MED,HEMATOL ONCOL SERV,FT SAM HOUSTON,TX 78234, USA. NR 7 TC 1 Z9 1 U1 0 U2 0 PU KARGER PI BASEL PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND SN 0001-5792 J9 ACTA HAEMATOL-BASEL JI Acta Haematol. PY 1994 VL 91 IS 4 BP 199 EP 200 PG 2 WC Hematology SC Hematology GA PQ306 UT WOS:A1994PQ30600006 PM 7976118 ER PT J AU GLASS, AR KIKENDALL, JW SOBIN, LH BOWEN, PE AF GLASS, AR KIKENDALL, JW SOBIN, LH BOWEN, PE TI SERUM CONCENTRATIONS OF INSULIN-LIKE GROWTH-FACTOR-I IN COLONIC NEOPLASIA SO ACTA ONCOLOGICA LA English DT Note ID FACTOR-I; CANCER; POLYPS C1 WALTER REED ARMY MED CTR,DEPT MED,GASTROENTEROL SERV,WASHINGTON,DC 20307. ARMED FORCES INST PATHOL,DIV GASTROINTEST PATHOL,WASHINGTON,DC 20306. UNIV ILLINOIS,DEPT NUTR & MED DIETET,CHICAGO,IL 60680. RP GLASS, AR (reprint author), WALTER REED ARMY MED CTR,DEPT MED,ENDOCRINOL SERV,7D,WASHINGTON,DC 20307, USA. FU NCI NIH HHS [NCI CA 36978] NR 10 TC 10 Z9 10 U1 0 U2 0 PU SCANDINAVIAN UNIVERSITY PRESS PI OSLO PA PO BOX 2959 TOYEN, JOURNAL DIVISION CUSTOMER SERVICE, N-0608 OSLO, NORWAY SN 0284-186X J9 ACTA ONCOL JI Acta Oncol. PY 1994 VL 33 IS 1 BP 70 EP 71 PG 2 WC Oncology SC Oncology GA ND588 UT WOS:A1994ND58800014 PM 8142129 ER PT J AU DERSTINE, HW AF DERSTINE, HW GP R & D ASSOC MILITARY FOOD & PACKAGING SYST TI THE HISTORY OF FOOD SAFETY IN THE MILITARY SO ACTIVITIES REPORT AND MINUTES OF WORK GROUPS & SUB-WORK GROUPS OF THE R & D ASSOCIATES: ACTIVITIES REPORT OF THE R & D ASSOCIATION SE ACTIVITIES REPORT OF THE R&D ASSOCIATES LA English DT Proceedings Paper CT 1993 Fall Meeting of R and D Associates - Food Safety: A Comprehensive View CY OCT 05-07, 1993 CL BOSTON, MA SP R & D ASSOC MILITARY FOOD & PACKING SYST C1 USA,HLTH SERV COMMAND,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 1 U2 1 PU RESEARCH & DEVELOPMENT ASSOC MILITARY FOOD PACKAGING SYSTEM PI SAN ANTONIO PA 16607 BLANCO RD, SUITE 305, SAN ANTONIO, TX 78232 SN 0198-0181 J9 ACT REP R&D PY 1994 VL 46 IS 1 BP 29 EP 38 PG 10 WC Food Science & Technology SC Food Science & Technology GA BB01G UT WOS:A1994BB01G00006 ER PT J AU KOWALCZYK, CA AF KOWALCZYK, CA GP R & D ASSOC MILITARY FOOD & PACKAGING SYST TI WHATS HAPPENING IN ARMY FOOD SO ACTIVITIES REPORT AND MINUTES OF WORK GROUPS & SUB-WORK GROUPS OF THE R & D ASSOCIATES: ACTIVITIES REPORT OF THE R & D ASSOCIATION SE ACTIVITIES REPORT OF THE R&D ASSOCIATES LA English DT Proceedings Paper CT 1993 Fall Meeting of R and D Associates - Food Safety: A Comprehensive View CY OCT 05-07, 1993 CL BOSTON, MA SP R & D ASSOC MILITARY FOOD & PACKING SYST C1 USA,WASHINGTON,DC 20012. NR 0 TC 0 Z9 0 U1 0 U2 0 PU RESEARCH & DEVELOPMENT ASSOC MILITARY FOOD PACKAGING SYSTEM PI SAN ANTONIO PA 16607 BLANCO RD, SUITE 305, SAN ANTONIO, TX 78232 SN 0198-0181 J9 ACT REP R&D PY 1994 VL 46 IS 1 BP 49 EP 52 PG 4 WC Food Science & Technology SC Food Science & Technology GA BB01G UT WOS:A1994BB01G00008 ER PT J AU HAND, W AF HAND, W GP R & D ASSOC MILITARY FOOD & PACKAGING SYST TI WHOS IN CHARGE BRIEFING SO ACTIVITIES REPORT AND MINUTES OF WORK GROUPS & SUB-WORK GROUPS OF THE R & D ASSOCIATES: ACTIVITIES REPORT OF THE R & D ASSOCIATION SE ACTIVITIES REPORT OF THE R&D ASSOCIATES LA English DT Proceedings Paper CT 1993 Fall Meeting of R and D Associates - Food Safety: A Comprehensive View CY OCT 05-07, 1993 CL BOSTON, MA SP R & D ASSOC MILITARY FOOD & PACKING SYST C1 USA,DIV TROOP SUPPORT,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU RESEARCH & DEVELOPMENT ASSOC MILITARY FOOD PACKAGING SYSTEM PI SAN ANTONIO PA 16607 BLANCO RD, SUITE 305, SAN ANTONIO, TX 78232 SN 0198-0181 J9 ACT REP R&D PY 1994 VL 46 IS 1 BP 84 EP 87 PG 4 WC Food Science & Technology SC Food Science & Technology GA BB01G UT WOS:A1994BB01G00014 ER PT J AU BORGEMEISTER, L AF BORGEMEISTER, L GP R & D ASSOC MILITARY FOOD & PACKAGING SYST TI UNITED-STATES-NAVY UPDATE SO ACTIVITIES REPORT AND MINUTES OF WORK GROUPS & SUB-WORK GROUPS OF THE R & D ASSOCIATES: ACTIVITIES REPORT OF THE R & D ASSOCIATION SE ACTIVITIES REPORT OF THE R&D ASSOCIATES LA English DT Proceedings Paper CT 1993 Fall Meeting of R and D Associates - Food Safety: A Comprehensive View CY OCT 05-07, 1993 CL BOSTON, MA SP R & D ASSOC MILITARY FOOD & PACKING SYST C1 USA,NATICK RES & DEV LABS,NAVY FOOD SERV SYST OFF,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU RESEARCH & DEVELOPMENT ASSOC MILITARY FOOD PACKAGING SYSTEM PI SAN ANTONIO PA 16607 BLANCO RD, SUITE 305, SAN ANTONIO, TX 78232 SN 0198-0181 J9 ACT REP R&D PY 1994 VL 46 IS 1 BP 117 EP 121 PG 5 WC Food Science & Technology SC Food Science & Technology GA BB01G UT WOS:A1994BB01G00020 ER PT J AU WAYNE, DH AF WAYNE, DH GP R & D ASSOC MILITARY FOOD & PACKAGING SYST TI UNITED-STATES-ARMY NATICK UPDATE SO ACTIVITIES REPORT AND MINUTES OF WORK GROUPS & SUB-WORK GROUPS OF THE R & D ASSOCIATES: ACTIVITIES REPORT OF THE R & D ASSOCIATION SE ACTIVITIES REPORT OF THE R&D ASSOCIATES LA English DT Proceedings Paper CT 1993 Fall Meeting of R and D Associates - Food Safety: A Comprehensive View CY OCT 05-07, 1993 CL BOSTON, MA SP R & D ASSOC MILITARY FOOD & PACKING SYST C1 USA,NATICK RES & DEV LABS,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU RESEARCH & DEVELOPMENT ASSOC MILITARY FOOD PACKAGING SYSTEM PI SAN ANTONIO PA 16607 BLANCO RD, SUITE 305, SAN ANTONIO, TX 78232 SN 0198-0181 J9 ACT REP R&D PY 1994 VL 46 IS 1 BP 122 EP 122 PG 1 WC Food Science & Technology SC Food Science & Technology GA BB01G UT WOS:A1994BB01G00021 ER PT B AU BERGQUIST, PR WENTWORTH, SE AF BERGQUIST, PR WENTWORTH, SE GP ADHES SOC TI AN ASSESSMENT OF THE BONDABILITY OF ALUMINUM OXIDE REINFORCED ALUMINUM SO ADHESION SOCIETY - PROCEEDINGS OF THE SEVENTEENTH ANNUAL MEETING AND THE SYMPOSIUM ON PARTICLE ADHESION LA English DT Proceedings Paper CT 17th Annual Meeting of the Adhesion-Society/Symposium on Particle Adhesion CY FEB 20-23, 1994 CL ORLANDO, FL SP ADHES SOC, LOCTITE CORP, NORTON CHEM C1 USA,RES LAB,MAT DIRECTORATE,POLYMER RES BRANCH,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 1 PU ADHESION SOCIETY PI BALTIMORE PA MARTIN MARIETTA LABORATORIES 1450 S ROLLING RD, BALTIMORE, MD 21227 PY 1994 BP 318 EP 319 PG 2 WC Engineering, Chemical; Engineering, Mechanical; Materials Science, Coatings & Films SC Engineering; Materials Science GA BB92Y UT WOS:A1994BB92Y00096 ER PT B AU SADLER, BM AF SADLER, BM BE Luk, FT TI 2ND-ORDER AND HIGHER-ORDER CYCLOSTATIONARY PROCESSING USING ACOUSTO-OPTICS SO ADVANCE SIGNAL PROCESSING: ALGORITHMS, ARCHITECTURES, AND IMPLEMENTATIONS V SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT 5th SPIE Conference on Advanced Signal Processing - Algorithms, Architectures, and Implementations CY JUL 24-27, 1994 CL SAN DIEGO, CA SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,RES LAB,ARLINGTON,VA 22209. NR 0 TC 0 Z9 0 U1 0 U2 1 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1620-7 J9 P SOC PHOTO-OPT INS PY 1994 VL 2296 BP 82 EP 92 DI 10.1117/12.190895 PG 11 WC Telecommunications SC Telecommunications GA BB83S UT WOS:A1994BB83S00008 ER PT B AU LIN, SS YIP, PW AF LIN, SS YIP, PW BE Masumoto, T Inoue, A Makiwshima, A Arnberg, L Doyama, M Baskes, MI Nieminen, R Kuribayashie, K Hashimoto, H Saghir, MZE Sawaoka, A Sokolowski, RS Walter, HU Kishi, T TI SURFACE AND ADHESION STUDIES OF CARBON FIBER MODIFIED BY LOW ENERGY ION BEAM SO ADVANCED MATERIALS '93, III - A & B: A: COMPUTATIONS, GLASSY MATERIALS, MICROGRAVITY AND NON-DESTRUCTIVE TESTING; B: COMPOSITES, GRAIN BOUNDARIES AND NANOPHASE MATERIALS SE TRANSACTIONS OF THE MATERIALS RESEARCH SOCIETY OF JAPAN LA English DT Proceedings Paper CT 3rd IUMRS International Conference on Advanced Materials (ICAM) CY AUG 31-SEP 04, 1993 CL SUNSHINE CITY, JAPAN SP INT UNION MAT RES SOC, NIKKAN KOGYO SHIMBUN LTD C1 USA,RES LAB,MAT DIRECTORATE,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 1 PU ELSEVIER SCIENCE PUBL B V PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS BN 0-444-81993-2 J9 T MRS JAP PY 1994 VL 16 IS A & B BP 889 EP 892 PG 4 WC Materials Science, Multidisciplinary; Materials Science, Characterization & Testing; Materials Science, Composites SC Materials Science GA BC69G UT WOS:A1994BC69G00199 ER PT J AU BHANSALI, KJ CHAMPAGNE, VK WECHSLER, G PEPI, M AF BHANSALI, KJ CHAMPAGNE, VK WECHSLER, G PEPI, M BE Pusey, HC Pusey, SC TI Failure analysis of an inconel 718 barrel nut from an army attack helicopter SO ADVANCED MATERIALS AND PROCESS TECHNOLOGY FOR MECHANICAL FAILURE PREVENTION LA English DT Proceedings Paper CT 48th Meeting of the Mechanical Failures Prevention Group - Advanced Materials and Process Technology for Mechanical Failure Prevention CY APR 19-21, 1994 CL WAKEFIELD, MA SP Mech Failures Prevent Grp, USN, Off Naval Res, Naval Surf Warfare Ctr, Naval Civil Engn Lab, USA Res Lab, Vibrat Inst DE FAILURE ANALYSIS; FRACTOGRAPHY; HYDROGEN CRACKING; INCONEL 718; STRESS-CORROSION CRACKING C1 USA,AVIAT & TROOP COMMAND,ST LOUIS,MO 63120. NR 0 TC 0 Z9 0 U1 0 U2 0 PU VIBRATION INST PI CLARENDON PA 101 W 55TH ST, CLARENDON, IL 60514 PY 1994 BP 115 EP 129 PG 3 WC Engineering, Mechanical; Materials Science, Ceramics; Metallurgy & Metallurgical Engineering; Materials Science, Characterization & Testing SC Engineering; Materials Science; Metallurgy & Metallurgical Engineering GA BD67K UT WOS:A1994BD67K00011 ER PT B AU PEPI, M CHAMPAGNE, V WECHSLER, G AF PEPI, M CHAMPAGNE, V WECHSLER, G BE Pusey, HC Pusey, SC TI Metallurgical examination of a failed mixer pivot support SO ADVANCED MATERIALS AND PROCESS TECHNOLOGY FOR MECHANICAL FAILURE PREVENTION LA English DT Proceedings Paper CT 48th Meeting of the Mechanical Failures Prevention Group - Advanced Materials and Process Technology for Mechanical Failure Prevention CY APR 19-21, 1994 CL WAKEFIELD, MA SP Mech Failures Prevent Grp, USN, Off Naval Res, Naval Surf Warfare Ctr, Naval Civil Engn Lab, USA Res Lab, Vibrat Inst DE FAILURE ANALYSIS; HIGH STRENGTH STEEL; HYDROGEN-ASSISTED STRESS CORROSION CRACKING C1 USA,RES LAB,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 1 PU VIBRATION INST PI CLARENDON PA 101 W 55TH ST, CLARENDON, IL 60514 PY 1994 BP 141 EP 149 PG 3 WC Engineering, Mechanical; Materials Science, Ceramics; Metallurgy & Metallurgical Engineering; Materials Science, Characterization & Testing SC Engineering; Materials Science; Metallurgy & Metallurgical Engineering GA BD67K UT WOS:A1994BD67K00013 ER PT B AU WECHSLER, G BROEK, D AF WECHSLER, G BROEK, D BE Pusey, HC Pusey, SC TI Metallurgical examination of the lau-7 nitrogen receiver failure SO ADVANCED MATERIALS AND PROCESS TECHNOLOGY FOR MECHANICAL FAILURE PREVENTION LA English DT Proceedings Paper CT 48th Meeting of the Mechanical Failures Prevention Group - Advanced Materials and Process Technology for Mechanical Failure Prevention CY APR 19-21, 1994 CL WAKEFIELD, MA SP Mech Failures Prevent Grp, USN, Off Naval Res, Naval Surf Warfare Ctr, Naval Civil Engn Lab, USA Res Lab, Vibrat Inst DE ACOUSTIC EMISSION; COMPOSITE; FILAMENT WINDING; FAILURE ANALYSIS; PRESSURE VESSEL; STAINLESS STEEL C1 USA,RES LAB,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 0 PU VIBRATION INST PI CLARENDON PA 101 W 55TH ST, CLARENDON, IL 60514 PY 1994 BP 161 EP 170 PG 4 WC Engineering, Mechanical; Materials Science, Ceramics; Metallurgy & Metallurgical Engineering; Materials Science, Characterization & Testing SC Engineering; Materials Science; Metallurgy & Metallurgical Engineering GA BD67K UT WOS:A1994BD67K00015 ER PT B AU WANG, WG AF WANG, WG BE Pusey, HC Pusey, SC TI Failure mechanisms of titanium aluminide alloys SO ADVANCED MATERIALS AND PROCESS TECHNOLOGY FOR MECHANICAL FAILURE PREVENTION LA English DT Proceedings Paper CT 48th Meeting of the Mechanical Failures Prevention Group - Advanced Materials and Process Technology for Mechanical Failure Prevention CY APR 19-21, 1994 CL WAKEFIELD, MA SP Mech Failures Prevent Grp, USN, Off Naval Res, Naval Surf Warfare Ctr, Naval Civil Engn Lab, USA Res Lab, Vibrat Inst DE FRACTURE MECHANISM; GAMMA TITANIUM ALUMINIDE; SUPER-ALPHA(2) TITANIUM ALUMINIDE; TITANIUM DIBORIDE; XD(R) C1 USA,RES LAB,MAT DIRECTORATE,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 0 PU VIBRATION INST PI CLARENDON PA 101 W 55TH ST, CLARENDON, IL 60514 PY 1994 BP 185 EP 194 PG 4 WC Engineering, Mechanical; Materials Science, Ceramics; Metallurgy & Metallurgical Engineering; Materials Science, Characterization & Testing SC Engineering; Materials Science; Metallurgy & Metallurgical Engineering GA BD67K UT WOS:A1994BD67K00017 ER PT B AU SWAB, JJ QUINN, GD AF SWAB, JJ QUINN, GD BE Pusey, HC Pusey, SC TI Fractography of advanced structural ceramics SO ADVANCED MATERIALS AND PROCESS TECHNOLOGY FOR MECHANICAL FAILURE PREVENTION LA English DT Proceedings Paper CT 48th Meeting of the Mechanical Failures Prevention Group - Advanced Materials and Process Technology for Mechanical Failure Prevention CY APR 19-21, 1994 CL WAKEFIELD, MA SP Mech Failures Prevent Grp, USN, Off Naval Res, Naval Surf Warfare Ctr, Naval Civil Engn Lab, USA Res Lab, Vibrat Inst DE ADVANCED CERAMICS; FLAW CHARACTERIZATION; FRACTOGRAPHY; FRACTURE ORIGINS; STANDARDIZATION C1 USA,RES LAB,MAT DIRECTORATE,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 0 PU VIBRATION INST PI CLARENDON PA 101 W 55TH ST, CLARENDON, IL 60514 PY 1994 BP 227 EP 236 PG 4 WC Engineering, Mechanical; Materials Science, Ceramics; Metallurgy & Metallurgical Engineering; Materials Science, Characterization & Testing SC Engineering; Materials Science; Metallurgy & Metallurgical Engineering GA BD67K UT WOS:A1994BD67K00020 ER PT B AU SNOHA, DJ AF SNOHA, DJ BE Pusey, HC Pusey, SC TI X-ray diffraction characterization of process-induced residual stress SO ADVANCED MATERIALS AND PROCESS TECHNOLOGY FOR MECHANICAL FAILURE PREVENTION LA English DT Proceedings Paper CT 48th Meeting of the Mechanical Failures Prevention Group - Advanced Materials and Process Technology for Mechanical Failure Prevention CY APR 19-21, 1994 CL WAKEFIELD, MA SP Mech Failures Prevent Grp, USN, Off Naval Res, Naval Surf Warfare Ctr, Naval Civil Engn Lab, USA Res Lab, Vibrat Inst DE ALUMINA CERAMIC; ARMOR STEEL; AUTOFRETTAGE; GRINDING; MECHANICAL FAILURE; POLYCRYSTALLINE MATERIALS; PROCESS; RESIDUAL STRESS; SHOT PEEN; WELDING; X-RAY DIFFRACTION C1 USA,RES LAB,MAT DIRECTORATE,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 0 PU VIBRATION INST PI CLARENDON PA 101 W 55TH ST, CLARENDON, IL 60514 PY 1994 BP 247 EP 256 PG 4 WC Engineering, Mechanical; Materials Science, Ceramics; Metallurgy & Metallurgical Engineering; Materials Science, Characterization & Testing SC Engineering; Materials Science; Metallurgy & Metallurgical Engineering GA BD67K UT WOS:A1994BD67K00022 ER PT B AU MEISSNER, K SINCEBAUGH, P AF MEISSNER, K SINCEBAUGH, P BE Pusey, HC Pusey, SC TI Preventing mechanical failures in resin transfer molding using embedded sensors and neural networks SO ADVANCED MATERIALS AND PROCESS TECHNOLOGY FOR MECHANICAL FAILURE PREVENTION LA English DT Proceedings Paper CT 48th Meeting of the Mechanical Failures Prevention Group - Advanced Materials and Process Technology for Mechanical Failure Prevention CY APR 19-21, 1994 CL WAKEFIELD, MA SP Mech Failures Prevent Grp, USN, Off Naval Res, Naval Surf Warfare Ctr, Naval Civil Engn Lab, USA Res Lab, Vibrat Inst DE ADAPTIVE CONTROL; CMAC; EMBEDDED SENSORS; REINFORCEMENT LEARNING; RESIN TRANSFER MOLDING; SMARTWEAVE C1 USA,RES LAB,MAT DIRECTORATE,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 0 PU VIBRATION INST PI CLARENDON PA 101 W 55TH ST, CLARENDON, IL 60514 PY 1994 BP 273 EP 282 PG 4 WC Engineering, Mechanical; Materials Science, Ceramics; Metallurgy & Metallurgical Engineering; Materials Science, Characterization & Testing SC Engineering; Materials Science; Metallurgy & Metallurgical Engineering GA BD67K UT WOS:A1994BD67K00024 ER PT J AU ILLI, OJ GREITZER, FL KANGAS, LJ REEVE, TJ AF ILLI, OJ GREITZER, FL KANGAS, LJ REEVE, TJ BE Pusey, HC Pusey, SC TI An artificial neural network system for diagnosing gas turbine engine fuel faults SO ADVANCED MATERIALS AND PROCESS TECHNOLOGY FOR MECHANICAL FAILURE PREVENTION LA English DT Proceedings Paper CT 48th Meeting of the Mechanical Failures Prevention Group - Advanced Materials and Process Technology for Mechanical Failure Prevention CY APR 19-21, 1994 CL WAKEFIELD, MA SP Mech Failures Prevent Grp, USN, Off Naval Res, Naval Surf Warfare Ctr, Naval Civil Engn Lab, USA Res Lab, Vibrat Inst DE ARTIFICIAL NEURAL NETWORKS; EXPERT SYSTEMS; FAULT DIAGNOSIS; PROGNOSTICS; TURBINE ENGINE MAINTENANCE C1 USA,ORDNANCE CTR & SCH,KNOWLEDGE ENGN GRP,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 0 Z9 0 U1 0 U2 0 PU VIBRATION INST PI CLARENDON PA 101 W 55TH ST, CLARENDON, IL 60514 PY 1994 BP 359 EP 367 PG 3 WC Engineering, Mechanical; Materials Science, Ceramics; Metallurgy & Metallurgical Engineering; Materials Science, Characterization & Testing SC Engineering; Materials Science; Metallurgy & Metallurgical Engineering GA BD67K UT WOS:A1994BD67K00031 ER PT B AU SINCEBAUGH, PJ AF SINCEBAUGH, PJ BE Pusey, HC Pusey, SC TI A general purpose image analysis inspection system SO ADVANCED MATERIALS AND PROCESS TECHNOLOGY FOR MECHANICAL FAILURE PREVENTION LA English DT Proceedings Paper CT 48th Meeting of the Mechanical Failures Prevention Group - Advanced Materials and Process Technology for Mechanical Failure Prevention CY APR 19-21, 1994 CL WAKEFIELD, MA SP Mech Failures Prevent Grp, USN, Off Naval Res, Naval Surf Warfare Ctr, Naval Civil Engn Lab, USA Res Lab, Vibrat Inst DE AUTOMATION; BACKPROPAGATION; IMAGE ANALYSIS; INSPECTION; NEURAL NETWORKS; PATTERN RECOGNITION; TESTING C1 USA,RES LAB,MAT DIRECTORATE,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 0 PU VIBRATION INST PI CLARENDON PA 101 W 55TH ST, CLARENDON, IL 60514 PY 1994 BP 393 EP 401 PG 3 WC Engineering, Mechanical; Materials Science, Ceramics; Metallurgy & Metallurgical Engineering; Materials Science, Characterization & Testing SC Engineering; Materials Science; Metallurgy & Metallurgical Engineering GA BD67K UT WOS:A1994BD67K00034 ER PT B AU KLEINMEYER, JD WHITE, GB AF KLEINMEYER, JD WHITE, GB BE Pusey, HC Pusey, SC TI A real-time vision system to monitor analyze the changes in composite specimens during mechanical testing SO ADVANCED MATERIALS AND PROCESS TECHNOLOGY FOR MECHANICAL FAILURE PREVENTION LA English DT Proceedings Paper CT 48th Meeting of the Mechanical Failures Prevention Group - Advanced Materials and Process Technology for Mechanical Failure Prevention CY APR 19-21, 1994 CL WAKEFIELD, MA SP Mech Failures Prevent Grp, USN, Off Naval Res, Naval Surf Warfare Ctr, Naval Civil Engn Lab, USA Res Lab, Vibrat Inst DE DIGITAL IMAGE PROCESSING; VISION SYSTEM; DAMAGE ASSESSMENT; COMPOSITE MATERIALS; FRACTURE; MECHANICAL TESTING; ENVIRONMENTAL DURABILITY C1 USA,RES LAB,MAT DIRECTORATE,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 0 PU VIBRATION INST PI CLARENDON PA 101 W 55TH ST, CLARENDON, IL 60514 PY 1994 BP 403 EP 409 PG 3 WC Engineering, Mechanical; Materials Science, Ceramics; Metallurgy & Metallurgical Engineering; Materials Science, Characterization & Testing SC Engineering; Materials Science; Metallurgy & Metallurgical Engineering GA BD67K UT WOS:A1994BD67K00035 ER PT B AU CHO, K BARON, I BARATTA, FI AF CHO, K BARON, I BARATTA, FI BE Pusey, HC Pusey, SC TI Fracture toughness measurements of two specimen geometries considering stability SO ADVANCED MATERIALS AND PROCESS TECHNOLOGY FOR MECHANICAL FAILURE PREVENTION LA English DT Proceedings Paper CT 48th Meeting of the Mechanical Failures Prevention Group - Advanced Materials and Process Technology for Mechanical Failure Prevention CY APR 19-21, 1994 CL WAKEFIELD, MA SP Mech Failures Prevent Grp, USN, Off Naval Res, Naval Surf Warfare Ctr, Naval Civil Engn Lab, USA Res Lab, Vibrat Inst DE FRACTURE TOUGHNESS; CRACK STABILITY; BEND BAR GEOMETRY; COMPLIANCE; ALUMINA; SILICON NITRIDE C1 USA,RES LAB,MAT DIRECTORATE,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 0 PU VIBRATION INST PI CLARENDON PA 101 W 55TH ST, CLARENDON, IL 60514 PY 1994 BP 421 EP 432 PG 4 WC Engineering, Mechanical; Materials Science, Ceramics; Metallurgy & Metallurgical Engineering; Materials Science, Characterization & Testing SC Engineering; Materials Science; Metallurgy & Metallurgical Engineering GA BD67K UT WOS:A1994BD67K00037 ER PT S AU HAN, WY COLE, MW CASAS, LM DEANNI, A WADE, M JONES, KA LAPORE, A LU, Y YANG, LW AF HAN, WY COLE, MW CASAS, LM DEANNI, A WADE, M JONES, KA LAPORE, A LU, Y YANG, LW BE Murarka, SP Katz, A Tu, KN Maex, K TI OHMIC CONTACTS TO P(+)-GAAS AND AL0.26GA0.74AS SO ADVANCED METALLIZATION FOR DEVICES AND CIRCUITS - SCIENCE, TECHNOLOGY AND MANUFACTURABILITY SE MATERIALS RESEARCH SOCIETY SYMPOSIUM PROCEEDINGS LA English DT Proceedings Paper CT Symposium on Advanced Metallization for Devices and Circuits: Science, Technology and Manufacturability CY APR 04-08, 1994 CL SAN FRANCISCO, CA SP MAT RES SOC C1 USA,RES LAB,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MATERIALS RESEARCH SOC PI PITTSBURGH PA 9800 MCKNIGHT RD, SUITE 327, PITTSBURGH, PA 15237 SN 0272-9172 BN 1-55899-237-5 J9 MATER RES SOC SYMP P PY 1994 VL 337 BP 301 EP 306 PG 6 WC Metallurgy & Metallurgical Engineering; Materials Science, Coatings & Films; Physics, Condensed Matter SC Metallurgy & Metallurgical Engineering; Materials Science; Physics GA BB59J UT WOS:A1994BB59J00035 ER PT S AU DUBEY, M JONES, KA CASAS, LM ECKART, D PFEFFER, RL AF DUBEY, M JONES, KA CASAS, LM ECKART, D PFEFFER, RL BE Murarka, SP Katz, A Tu, KN Maex, K TI SINGLE-CRYSTAL EPITAXIAL GE BASED CONTACTS TO GAAS, AND INGAP SO ADVANCED METALLIZATION FOR DEVICES AND CIRCUITS - SCIENCE, TECHNOLOGY AND MANUFACTURABILITY SE MATERIALS RESEARCH SOCIETY SYMPOSIUM PROCEEDINGS LA English DT Proceedings Paper CT Symposium on Advanced Metallization for Devices and Circuits: Science, Technology and Manufacturability CY APR 04-08, 1994 CL SAN FRANCISCO, CA SP MAT RES SOC C1 USA,RES LAB,EPSD,AMSRL EP EC,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 1 PU MATERIALS RESEARCH SOC PI PITTSBURGH PA 9800 MCKNIGHT RD, SUITE 327, PITTSBURGH, PA 15237 SN 0272-9172 BN 1-55899-237-5 J9 MATER RES SOC SYMP P PY 1994 VL 337 BP 601 EP 606 PG 6 WC Metallurgy & Metallurgical Engineering; Materials Science, Coatings & Films; Physics, Condensed Matter SC Metallurgy & Metallurgical Engineering; Materials Science; Physics GA BB59J UT WOS:A1994BB59J00076 ER PT S AU MCLANE, GF CASAS, L REID, JS KOLAWA, E NICOLET, MA AF MCLANE, GF CASAS, L REID, JS KOLAWA, E NICOLET, MA BE Murarka, SP Katz, A Tu, KN Maex, K TI DRY-ETCHING OF TA-SI-N DIFFUSION BARRIER MATERIAL IN CF4+O2 GAS-MIXTURES SO ADVANCED METALLIZATION FOR DEVICES AND CIRCUITS - SCIENCE, TECHNOLOGY AND MANUFACTURABILITY SE MATERIALS RESEARCH SOCIETY SYMPOSIUM PROCEEDINGS LA English DT Proceedings Paper CT Symposium on Advanced Metallization for Devices and Circuits: Science, Technology and Manufacturability CY APR 04-08, 1994 CL SAN FRANCISCO, CA SP MAT RES SOC C1 USA,RES LAB,FT MONMOUTH,NJ 07703. NR 0 TC 1 Z9 1 U1 0 U2 0 PU MATERIALS RESEARCH SOC PI PITTSBURGH PA 9800 MCKNIGHT RD, SUITE 327, PITTSBURGH, PA 15237 SN 0272-9172 BN 1-55899-237-5 J9 MATER RES SOC SYMP P PY 1994 VL 337 BP 669 EP 674 PG 6 WC Metallurgy & Metallurgical Engineering; Materials Science, Coatings & Films; Physics, Condensed Matter SC Metallurgy & Metallurgical Engineering; Materials Science; Physics GA BB59J UT WOS:A1994BB59J00087 ER PT B AU SHARP, MA NINDL, BC WESTPHAL, KA FRIEDL, KE AF SHARP, MA NINDL, BC WESTPHAL, KA FRIEDL, KE BE Aghazadeh, F TI The physical performance of female army basic trainees who pass and fail the army body weight and percent body fat standards SO ADVANCES IN INDUSTRIAL ERGONOMICS AND SAFETY VI SE ADVANCES IN INDUSTRIAL ERGONOMICS AND SAFETY LA English DT Proceedings Paper CT Annual International Industrial Ergonomics and Safety Conference CY JUN 07-10, 1994 CL SAN ANTONIO, TX SP Int Fdn Ind Ergon & Safety Res RP USA,ENVIRONM MED RES INST,DIV OCCUPAT PHYSIOL,NATICK,MA 01760, USA. NR 0 TC 1 Z9 1 U1 0 U2 0 PU TAYLOR & FRANCIS LTD PI LONDON PA 4 JOHN ST, LONDON, ENGLAND WC1N 2ET BN 0-7484-0085-0 J9 ADV IND ERG PY 1994 BP 743 EP 750 PG 8 WC Ergonomics SC Engineering GA BD37T UT WOS:A1994BD37T00109 ER PT J AU GENDELMAN, HE GENIS, P JETT, M ZHAI, QH NOTTET, HSLM AF GENDELMAN, HE GENIS, P JETT, M ZHAI, QH NOTTET, HSLM TI AN EXPERIMENTAL-MODEL SYSTEM FOR HIV-1-INDUCED BRAIN INJURY SO ADVANCES IN NEUROIMMUNOLOGY LA English DT Article; Proceedings Paper CT 3rd Workshop on Neuro-AIDS CY AUG 16-19, 1993 CL PORTLAND, ME SP NIAID, DIV AIDS ID CENTRAL-NERVOUS-SYSTEM; VIRUS-INFECTED MACROPHAGES; IMMUNE-DEFICIENCY-SYNDROME; TUMOR-NECROSIS-FACTOR; FACTOR PAF-ACETHER; MONOCYTES; HIV-1; AIDS; NEUROTOXICITY; INTERLEUKIN-1 AB The pathological hallmark of HIV infection in brain is productive viral replication in cells of mononuclear phagocyte lineage including brain macrophages, microglia and multinucleated giant cells (Koenig et al., 1986; Wiley et al., 1986; Gabuzda er al., 1986; Stoler et al., 1986). These cells secrete viral and cell encoded neurotoxins that lead to neuronal injury, glial proliferation and myelin pallor during advancing disease (Genis et al., 1992; Giulian er al., 1990, 1993; Pulliam et al., 1991). The apparent paradox between the distribution and numbers of virus infected cells and brain tissue pathology support indirect mechanisms for CNS damage (Epstein, 1993; Geleziunas et al., 1992; Merrill and Chen, 1992; Michaels et al., 1988; Price er al., 1988). First, brain macrophages and microglia can produce neurotoxins by secretion of viral proteins (for example, gp120) (Dawson et al., 1991; Merrill et al., 1989; Lipton et al., 1990; Lipton, 1993). Second, HIV primes macrophages for immune activation to produce neurotoxins including: cytokines (TNF alpha and IL-1 beta), eicosanoids, quinolinate and nitric oxide (NO). Chronic immune stimulation mediated by opportunistic infections and chronic interferon gamma (IFN gamma) production (in and outside the CNS) continues the process of macrophage activation leading to progressive neural injury. The hyperresponsiveness of HIV-infected macrophages to activation results in production of cellular factors that activate uninfected macrophages. This suggests that HIV-infected macrophages are both perpetrators and amplifiers for neurotoxic activities. C1 UNIV NEBRASKA,MED CTR,DEPT PATHOL & MICROBIOL,OMAHA,NE 68198. UNIV NEBRASKA,MED CTR,EPPLEY INST RES CANC & ALLIED DIS,OMAHA,NE 68198. WALTER REED ARMY MED CTR,WALTER REED ARMY INST RES,DEPT MOLEC PATHOL,WASHINGTON,DC 20307. CREIGHTON UNIV,SCH MED,DEPT NEUROL,OMAHA,NE 68131. RP GENDELMAN, HE (reprint author), UNIV NEBRASKA,MED CTR,DEPT MED,600 S 42ND ST,OMAHA,NE 68198, USA. FU NHLBI NIH HHS [P01 HL43628-05]; NINDS NIH HHS [P01 NS31492-01] NR 29 TC 39 Z9 41 U1 0 U2 2 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0960-5428 J9 ADV NEUROIMMUNOL JI Adv. Neuroimmunol. PY 1994 VL 4 IS 3 BP 189 EP 193 DI 10.1016/S0960-5428(06)80256-1 PG 5 WC Immunology; Neurosciences SC Immunology; Neurosciences & Neurology GA PP109 UT WOS:A1994PP10900007 PM 7874386 ER PT S AU DOWDING, RJ STIGLICH, JJ SUDARSHAN, TS AF DOWDING, RJ STIGLICH, JJ SUDARSHAN, TS BE Lall, C Neupaver, AJ TI SYNTHESIS AND CONSOLIDATION OF NANOPARTICLES SO ADVANCES IN POWDER METALLURGY & PARTICULATE MATERIALS - 1994, VOL 5: SPECIALTY MATERIALS AND COMPOSITES SE ADVANCES IN POWDER METALLURGY & PARTICULATE MATERIALS LA English DT Proceedings Paper CT 1994 International Conference and Exhibition on Powder Metallurgy and Particulate Materials CY MAY 08-11, 1994 CL TORONTO, CANADA SP MET POWDER IND FEDERAT, APMI INT C1 USA,RES LAB,MAT DIRECTORATE,WATERTOWN,MA 02172. RI Dowding, Robert/F-1469-2015 OI Dowding, Robert/0000-0002-4763-2131 NR 0 TC 0 Z9 0 U1 0 U2 0 PU METAL POWDER INDUSTRIES FED PI PRINCETON PA 105 COLLEGE ROAD EAST, PRINCETON, NJ 08540-6692 SN 1065-5824 BN 1-878954-49-0 J9 ADV PM PART PY 1994 BP 45 EP 58 PG 14 WC Metallurgy & Metallurgical Engineering; Materials Science, Composites SC Metallurgy & Metallurgical Engineering; Materials Science GA BC45Z UT WOS:A1994BC45Z00004 ER PT S AU RYAN, KF DOWDING, RJ AF RYAN, KF DOWDING, RJ BE Lall, C Neupaver, AJ TI THERMOMECHANICAL STUDIES OF TUNGSTEN HEAVY ALLOYS SO ADVANCES IN POWDER METALLURGY & PARTICULATE MATERIALS - 1994, VOL 5: SPECIALTY MATERIALS AND COMPOSITES SE ADVANCES IN POWDER METALLURGY & PARTICULATE MATERIALS LA English DT Proceedings Paper CT 1994 International Conference and Exhibition on Powder Metallurgy and Particulate Materials CY MAY 08-11, 1994 CL TORONTO, CANADA SP MET POWDER IND FEDERAT, APMI INT C1 USA,RES LAB,MAT DIRECTORATE,WATERTOWN,MA 02172. RI Dowding, Robert/F-1469-2015 OI Dowding, Robert/0000-0002-4763-2131 NR 0 TC 0 Z9 0 U1 0 U2 0 PU METAL POWDER INDUSTRIES FED PI PRINCETON PA 105 COLLEGE ROAD EAST, PRINCETON, NJ 08540-6692 SN 1065-5824 BN 1-878954-49-0 J9 ADV PM PART PY 1994 BP 289 EP 302 PG 14 WC Metallurgy & Metallurgical Engineering; Materials Science, Composites SC Metallurgy & Metallurgical Engineering; Materials Science GA BC45Z UT WOS:A1994BC45Z00021 ER PT B AU POLI, LC KONDEK, CA AF POLI, LC KONDEK, CA BE Nalamasu, O TI A HIGH-CONTRAST DEEP-SUBMICRON E-BEAM LITHOGRAPHY PROCESS FOR FABRICATING PLANAR WAVE-GUIDE OPTICAL GRATINGS ON GAAS SO ADVANCES IN RESIST TECHNOLOGY AND PROCESSING XI SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Advances in Resist Technology and Processing XI Conference/SPIE 1994 Symposium on Microlithography CY FEB 27-MAR 04, 1994 CL SAN JOSE, CA SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS, SEMICOND EQUIPMENT & MAT INT C1 USA,RES LAB,ELECTR & POWER SOURCES DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1490-5 J9 P SOC PHOTO-OPT INS PY 1994 VL 2195 BP 858 EP 865 DI 10.1117/12.175398 PG 8 WC Optics SC Optics GA BA89Y UT WOS:A1994BA89Y00073 ER PT J AU SUTHERLAND, RA KHANNA, RK OSPINA, MJ AF SUTHERLAND, RA KHANNA, RK OSPINA, MJ TI INFRARED PROPERTIES OF ATMOSPHERIC AEROSOL CONSTITUENTS - POLYAROMATIC HYDROCARBONS AND TERPENES SO AEROSOL SCIENCE AND TECHNOLOGY LA English DT Article ID WESTERN UNITED-STATES; ORGANIC-MATTER; TROPOSPHERE; COMBUSTION; EMISSIONS AB The infrared spectra (2-20 mum) of six terpene samples and six polyaromatic hydrocarbon (PAH) samples are presented and compared with similar spectra obtained from standard grade petroleum (fog oil) samples. The selected samples are representative of the various different molecular structures that may be present in atmospheric aerosol sources, particularly fire smokes. Results are presented in terms of the wavelength-dependent complex refractive indices as obtained from bulk phase (thin layer) transmittance measurements and the Kramers-Kronig relationships. All samples exhibit a characteristic complex absorption spectra with numerous line absorption features in the 8-14-mum atmospheric window regions with peak imaginary indices nominally around 0.10-0.12 for the terpene samples and on the order of 1.0-1.2 for the PAH samples, although there are far fewer lines in the PAH samples than in the terpene samples. The terpenes also exhibit absorption features in the 3-5-mum window which are much like those found in the standard samples but are not observed in the PAH samples. C1 UNIV MARYLAND,DEPT CHEM & BIOCHEM,COLL PK,MD 20742. RP SUTHERLAND, RA (reprint author), USA,RES LAB,BATTLEFIELD ENVIRONM DIRECTORATE,ATTN AMSRL-BE-E,WHITE SANDS MISSILE RANGE,NM 88002, USA. NR 24 TC 6 Z9 6 U1 0 U2 5 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0278-6826 J9 AEROSOL SCI TECH JI Aerosol Sci. Technol. PD JAN PY 1994 VL 20 IS 1 BP 62 EP 70 DI 10.1080/02786829408959664 PG 9 WC Engineering, Chemical; Engineering, Mechanical; Environmental Sciences; Meteorology & Atmospheric Sciences SC Engineering; Environmental Sciences & Ecology; Meteorology & Atmospheric Sciences GA NF881 UT WOS:A1994NF88100005 ER PT B AU DAVID, P EMMERMAN, P HO, S AF DAVID, P EMMERMAN, P HO, S GP AIAA TI A SCALABLE ARCHITECTURE SYSTEM FOR AUTOMATIC TARGET RECOGNITION SO AIAA/IEEE DIGITAL AVIONICS SYSTEMS CONFERENCE - 13TH DASC LA English DT Proceedings Paper CT 13th AIAA/IEEE Digital Avionics Systems Conference (13th DASC) CY OCT 30-NOV 03, 1994 CL PHOENIX, AZ SP AIAA, IEEE C1 USA,RES LAB,ADELPHI,MD 20783. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-2425-0 PY 1994 BP 414 EP 420 DI 10.1109/DASC.1994.369448 PG 7 WC Engineering, Aerospace SC Engineering GA BB78Z UT WOS:A1994BB78Z00066 ER PT J AU ALVING, CR WASSEF, NM AF ALVING, CR WASSEF, NM TI CYTOTOXIC T-LYMPHOCYTES INDUCED BY LIPOSOMAL ANTIGENS - MECHANISMS OF IMMUNOLOGICAL PRESENTATION SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Article; Proceedings Paper CT Advances in AIDS Vaccine Development - 6th Annual Meeting of the National-Cooperative-Vaccine-Development-Group-for-AIDS CY OCT 30-NOV 04, 1993 CL ALEXANDRIA, VA SP NATL COOPERAT VACCINE DEV GRP AIDS, NIAID, DIV AIDS, VACCINE TEAM, FOGARTY INT CTR, AIDS INT TRAINING RES PROGRAM, CTR DIS CONTROL & PREVENT, FDA, NIDA, US AGCY INT DEV, NIAID, OFF TROP MED & INT RES, WHO, GLOBAL PROGRAMME AIDS ID PH-SENSITIVE LIPOSOMES; CLASS-I PRESENTATION; ENCAPSULATED ANTIGENS; SOLUBLE-PROTEIN; PRESENTATION PATHWAY; SYNTHETIC PEPTIDE; IMMUNE-RESPONSES; GOLGI-APPARATUS; HEPATITIS-A; LIPID-A AB It is known that liposomes can deliver encapsulated substances, including drugs and antigens, to lysosomes in macrophages. Because of this it has been assumed that although liposomes might be useful for induction of humoral (class II) immunity, they would not be capable of cytoplasmic delivery of antigen for introduction into the class I pathway leading to induction of cytotoxic T lymphocytes (CTLs). However, experiments conducted by numerous laboratories, including our own, have demonstrated the ability to induce CTLs either in vitro with cultured cells incubated with liposome-associated antigen, or in vivo after immunization of mice or monkeys with liposomes containing associated antigen. Using a monoclonal antibody that recognizes repeating sequences of tetrapeptide epitopes derived from the circumsporozoite protein of Plasmodium falciparum, it has been shown by immunogold electron microscopy that liposomal antigenic epitopes can actually spill from endosomes into the cytoplasm of cultured macrophages. On the basis of this observation, a theoretical intracellular pathway is proposed whereby liposomal antigen is processed by macrophages through a cytoplasmic process that results in delivery of antigenic epitopes to the Golgi apparatus and the endoplasmic reticulum. The liposomal antigenic epitopes would then have the opportunity to associate with class I MHC molecules and undergo vesicular transport to the surface of the cells for presentation and induction of CTLs. RP ALVING, CR (reprint author), WALTER REED ARMY INST RES,DEPT MEMBRANE BIOCHEM,WASHINGTON,DC 20307, USA. NR 45 TC 33 Z9 33 U1 0 U2 0 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PY 1994 VL 10 SU 2 BP S91 EP S94 PG 4 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA PT118 UT WOS:A1994PT11800046 PM 7532427 ER PT J AU BIRX, DL REDFIELD, R DAVIS, C MELCHER, G RUIZ, N WAGNER, K JOHNSON, S ARONSON, N OSTER, C LENNOX, J BURKE, D AF BIRX, DL REDFIELD, R DAVIS, C MELCHER, G RUIZ, N WAGNER, K JOHNSON, S ARONSON, N OSTER, C LENNOX, J BURKE, D TI ACTIVE IMMUNIZATION OF AZT-TREATED HIV-1-INFECTED PATIENTS WITH RECOMBINANT RGP160 (MGS) SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DEPT RETROVIRAL RES,ROCKVILLE,MD 20850. RI Lennox, Jeffrey/D-1654-2014 OI Lennox, Jeffrey/0000-0002-2064-5565 NR 0 TC 0 Z9 0 U1 0 U2 1 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PY 1994 VL 10 SU 2 BP S158 EP S158 PG 1 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA PT118 UT WOS:A1994PT11800085 ER PT J AU BURNETT, PR POLONIS, V VANCOTT, TC BIRX, DL REDFIELD, RR AF BURNETT, PR POLONIS, V VANCOTT, TC BIRX, DL REDFIELD, RR TI IMMUNOGLOBULIN A-MEDIATED NEUTRALIZATION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,ROCKVILLE,MD 20850. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PY 1994 VL 10 SU 2 BP S34 EP S34 PG 1 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA PT118 UT WOS:A1994PT11800015 ER PT J AU GARTNER, S LIU, YL LEWIS, MG POLONIS, V ELKINS, WR ZACK, PM MIAO, J HUNTER, EA GREENHOUSE, J EDDY, GA AF GARTNER, S LIU, YL LEWIS, MG POLONIS, V ELKINS, WR ZACK, PM MIAO, J HUNTER, EA GREENHOUSE, J EDDY, GA TI HIV-1 INFECTION IN PIGTAILED MACAQUES SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Article; Proceedings Paper CT Advances in AIDS Vaccine Development - 6th Annual Meeting of the National-Cooperative-Vaccine-Development-Group-for-AIDS CY OCT 30-NOV 04, 1993 CL ALEXANDRIA, VA SP NATL COOPERAT VACCINE DEV GRP AIDS, NIAID, DIV AIDS, VACCINE TEAM, FOGARTY INT CTR, AIDS INT TRAINING RES PROGRAM, CTR DIS CONTROL & PREVENT, FDA, NIDA, US AGCY INT DEV, NIAID, OFF TROP MED & INT RES, WHO, GLOBAL PROGRAMME AIDS ID HUMAN-IMMUNODEFICIENCY-VIRUS; GLYCOPROTEIN GP120; MACACA-NEMESTRINA; CHIMPANZEES; TYPE-1; IMMUNIZATION; RECOMBINANT; CHALLENGE; MODEL; AIDS AB Four pigtailed macaques were inoculated with autologous cells expressing low levels of human immunodeficiency virus type 1 (HIV-1). During the first 10 weeks, infectious virus was recovered from peripheral blood mononuclear cells (PBMCs) and lymph nodes from three of the animals. Subsequently, HIV-1 DNA was frequently detected in uncultured PBMCs from all three animals, and virus was isolated from one of them at weeks 38 and 61. The fourth animal, which was rechallenged at week 10 with cell-free virus isolated from one of the others, never became virus isolation positive, but harbored HIV-1 proviral genomes. These virus infections were accompanied by the development of varied HIV-1-specific humoral immune responses. Antibodies to gp160 were first apparent at week 8 in the three initially infected animals and persisted. The animal from whom virus was isolated at late times also developed persisting antibodies to HIV-1 p24 and gp120. Antibodies to gp120 and gp160 became apparent in the rechallenged animal at 1 week following reinoculation, but they waned with time. In vivo passage of the virus was attempted at week 6. One recipient pigtailed macaque and one recipient cynomolgus monkey failed to become detectably infected following transfusion of virus-positive blood and lymph node cells. The long-term presence of HIV-1-specific antibodies and proviral genomes in these animals, and the recovery of infectious virus more than 1 year following inoculation, are indicative of persistent infection, and confirm previous reports that pigtailed macaques are susceptible to HIV-1. C1 WALTER REED ARMY INST RES,DIV RETROVIROL,DEPT RETROVIRAL RES,ROCKVILLE,MD 20850. NIAID,INFECT DIS LAB,BETHESDA,MD 20892. RP GARTNER, S (reprint author), HENRY M JACKSON FDN RES LAB,1600 E GUDE DR,ROCKVILLE,MD 20850, USA. NR 12 TC 12 Z9 12 U1 0 U2 0 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PY 1994 VL 10 SU 2 BP S129 EP S133 PG 5 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA PT118 UT WOS:A1994PT11800058 PM 7865287 ER PT J AU MASCOLA, J WEISLOW, O SNYDER, S BELAY, S YEAGER, M MCCUTCHAN, F MCNEIL, J BURKE, D WALKER, MC AF MASCOLA, J WEISLOW, O SNYDER, S BELAY, S YEAGER, M MCCUTCHAN, F MCNEIL, J BURKE, D WALKER, MC TI NEUTRALIZING ANTIBODY-ACTIVITY IN SERA FROM HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 VACCINE RECIPIENTS FROM THE AIDS VACCINE CLINICAL-TRIALS NETWORK SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DIV RETROVIROL,ROCKVILLE,MD 20850. NR 0 TC 9 Z9 9 U1 1 U2 1 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PY 1994 VL 10 SU 2 BP S55 EP S55 PG 1 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA PT118 UT WOS:A1994PT11800023 ER PT J AU MCNEIL, JG AF MCNEIL, JG TI HIV-1 VACCINE RESEARCH AND EVALUATION IN THAILAND - THE ROYAL-THAI-ARMY UNITED-STATES-ARMY HIV-1 RESEARCH COLLABORATION (RTA-USA HRC) SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DIV RETROVIROL,ROCKVILLE,MD 20850. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PY 1994 VL 10 SU 2 BP S247 EP S247 PG 1 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA PT118 UT WOS:A1994PT11800115 ER PT J AU REDFIELD, RR BIRX, DL BRUNDAGE, J ARONSON, N JOHNSON, S KIM, J LENNOX, J MICHAEL, N ROBB, M SITZ, K OSTER, C BURKE, DS AF REDFIELD, RR BIRX, DL BRUNDAGE, J ARONSON, N JOHNSON, S KIM, J LENNOX, J MICHAEL, N ROBB, M SITZ, K OSTER, C BURKE, DS TI LONG-TERM CLINICAL FOLLOW-UP OF VOLUNTEERS ENROLLED IN AN RGP160 PHASE-1 SAFETY AND IMMUNOGENICITY VACCINE THERAPY TRIAL SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DEPT RETROVIRAL RES,ROCKVILLE,MD 20850. RI Lennox, Jeffrey/D-1654-2014 OI Lennox, Jeffrey/0000-0002-2064-5565 NR 0 TC 0 Z9 0 U1 0 U2 1 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PY 1994 VL 10 SU 2 BP S157 EP S157 PG 1 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA PT118 UT WOS:A1994PT11800081 ER PT J AU SITZ, KV VANCOTT, TC DARDEN, JM REDFIELD, RR BIRX, DL AF SITZ, KV VANCOTT, TC DARDEN, JM REDFIELD, RR BIRX, DL TI NAIVE AND MEMORY T-LYMPHOCYTES IN THE CONTEXT OF A PHASE-I GP160 VACCINE THERAPY TRIAL SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DEPT RETROVIRAL RES,WASHINGTON,DC. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PY 1994 VL 10 SU 2 BP S159 EP S159 PG 1 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA PT118 UT WOS:A1994PT11800088 ER PT B AU SABIO, V CHELLAPPA, R AF SABIO, V CHELLAPPA, R BE Giglio, DA TI EFFICIENT METHOD OF TARGET RECOGNITION BASED ON SPECTRAL CORRELATION OF WIDE-BAND RESONANCE EFFECTS SO ALGORITHMS FOR SYNTHETIC APERTURE RADAR IMAGERY SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Algorithms for Synthetic Aperture Radar Imagery CY APR 06-07, 1994 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,RES LAB,ADELPHI,MD 20783. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1534-0 J9 P SOC PHOTO-OPT INS PY 1994 VL 2230 BP 328 EP 335 DI 10.1117/12.177182 PG 8 WC Engineering, Electrical & Electronic; Optics SC Engineering; Optics GA BA83Z UT WOS:A1994BA83Z00026 ER PT J AU GILCHRIST, W BURKHALTER, E EATON, C SCHAUDIES, RP MAYDONOVITCH, C ANDRADA, F MAGED, AR WONG, RKH AF GILCHRIST, W BURKHALTER, E EATON, C SCHAUDIES, RP MAYDONOVITCH, C ANDRADA, F MAGED, AR WONG, RKH TI THE EFFECT OF INDOMETHACIN ON THE SECRETION OF HUMAN SALIVARY EPIDERMAL GROWTH-FACTOR SO AMERICAN JOURNAL OF GASTROENTEROLOGY LA English DT Article ID INDUCED GASTRIC-LESIONS; PEPTIC-ULCER; RATS; DISEASE; DRUGS AB Ulceration associated with nonsteroidal anti-inflammatory drug (NSAID) use is a common problem in elderly patients. The postulated cause of NSAID ulceration is multifactorial but is probably related to the inhibition of the cyclo-oxygenase pathway and a subsequent decrease in mucosal prostaglandin levels. Epidermal growth factor (EGF), on the other hand, has been shown to be gastroprotective, stimulating DNA synthesis, and preventing ASA-induced gastric ulceration. Since EGF is important in gastric mucosal protection, we questioned whether the potential ulcerogenic properties of indomethacin were related in part to decreasing salivary EGF. Twenty healthy male volunteers with no gastrointestinal complaints received indomethacin 50 mg P.O. t.i.d. for 3 consecutive days. Saliva and serum were collected before indomethacin treatment and repeated 2 h after the last indomethacin dose. Stimulated salivary samples were collected for 15 min in fasted subjects and assayed for EGF, whereas serum indomethacin levels were determined by high-performance liquid chromatography. EGF levels significantly decreased by 33% after indomethacin (p<0.03), and this decrement was linearly related to serum indomethacin concentrations (r=0.58; p<0.048). Salivary output did not change after indomethacin treatment. Based on this data, we concluded that indomethacin's ulcerogenic properties may be related to its prostaglandin inhibitory properties as well as its ability to decrease salivary EGF output. C1 WALTER REED ARMY MED CTR,DEPT MED,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,DEPT CLIN INVEST,WASHINGTON,DC 20307. NR 22 TC 12 Z9 12 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0002-9270 J9 AM J GASTROENTEROL JI Am. J. Gastroenterol. PD JAN PY 1994 VL 89 IS 1 BP 97 EP 100 PG 4 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA MQ446 UT WOS:A1994MQ44600018 PM 8273807 ER PT J AU CRESPO, I MURPHY, J WONG, RKH AF CRESPO, I MURPHY, J WONG, RKH TI SUPERIOR MESENTERIC VENOUS THROMBOSIS MASQUERADING AS CROHNS-DISEASE SO AMERICAN JOURNAL OF GASTROENTEROLOGY LA English DT Note ID PROTEIN-C DEFICIENCY AB Superior mesenteric venous (SMV) thrombosis is an uncommon cause of mesenteric ischemia, frequently presenting with nonspecific and subacute symptoms. We report a case of a 28-yr-old man presenting with symptoms and radiographic changes suggestive of Crohn's disease who, upon further evaluation, was found to have SMV thrombosis. A search for a precipitating condition revealed a strong family history of thromboembolic disease and deficiency of protein C. The patient responded to supportive therapy and anticoagulation. C1 WALTER REED ARMY MED CTR,DEPT MED,GASTROENTEROL SERV,WASHINGTON,DC 20507. NR 8 TC 14 Z9 14 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0002-9270 J9 AM J GASTROENTEROL JI Am. J. Gastroenterol. PD JAN PY 1994 VL 89 IS 1 BP 116 EP 118 PG 3 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA MQ446 UT WOS:A1994MQ44600023 PM 8273778 ER PT J AU POWERS, JM AF POWERS, JM TI UNTITLED - RESPONSE SO AMERICAN JOURNAL OF GASTROENTEROLOGY LA English DT Letter RP POWERS, JM (reprint author), TRIPLER ARMY MED CTR,DEPT FAMILY PRACTICE & COMMUNITY MED,239-B HIBISCUS ST,HONOLULU,HI 96818, USA. NR 2 TC 0 Z9 0 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0002-9270 J9 AM J GASTROENTEROL JI Am. J. Gastroenterol. PD JAN PY 1994 VL 89 IS 1 BP 138 EP 138 PG 1 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA MQ446 UT WOS:A1994MQ44600032 PM 8273788 ER PT J AU IZUTSU, KT FATHERAZI, S WELLNER, RB HERRINGTON, J BELTON, CM ODA, D AF IZUTSU, KT FATHERAZI, S WELLNER, RB HERRINGTON, J BELTON, CM ODA, D TI CHARACTERISTICS AND REGULATION OF A MUSCARINICALLY ACTIVATED K-CURRENT IN HSG-PA CELLS SO AMERICAN JOURNAL OF PHYSIOLOGY LA English DT Article DE SALIVARY GLAND; DUCTAL CELLS; PATCH CLAMPING; POTASSIUM CHANNELS; CALCIUM-ACTIVATED CHANNELS; CELL SIGNALING ID PAROTID ACINAR-CELLS; CALCIUM RELEASE; SMOOTH-MUSCLE; EXOCRINE GLANDS; CA-2+ RELEASE; RECEPTOR; LINE; RAT; CHANNELS; HEPARIN AB Whole cell currents were measured in HSG-PA cells (a proposed model for salivary gland duct cells) after muscarinic receptor activation or exposure to known signaling agents. Exposure to carbachol or oxotremorine M produced large and often oscillatory increases in outward current whose reversal potentials indicated a K current. The current was sensitive to extracellular atropine, charybdotoxin, and quinine, but not apamin, and to 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid in the pipette. The response was prolonged or increased by guanosine 5'-O-(3-thiotriphosphate) and mimicked by D-myo-inositol 1,4,5-trisphosphate (IP3) or heparin in the pipette and by extracellular Ca ionophores. Tetraethylammonium indirectly inhibited the response via the muscarinic receptor. Fura 2 in cell suspensions showed that muscarinic agonists increased cytosolic Ca ion concentration ([Ca2+](i)) five to sevenfold, and measurements with indo 1 in individual cells showed that the oscillatory changes in outward current were tightly correlated with parallel changes in [Ca2+](i). The results indicate that muscarinic receptor stimulation of HSG-PA cells activates Ca2+-activated K channels through a signaling pathway involving a G protein, IP3 production, and increased [Ca2+](i) levels. These findings are similar to those in salivary gland acinar cells. C1 UNIV WASHINGTON,SCH DENT,DEPT PHYSIOL,SEATTLE,WA 98195. UNIV WASHINGTON,SCH MED,DEPT ORAL BIOL,SEATTLE,WA 98195. UNIV WASHINGTON,SCH MED,DEPT PHYSIOL,SEATTLE,WA 98195. USA,MED RES INST INFECT DIS,DIV TOXICOL,FREDERICK,MD 21702. RP IZUTSU, KT (reprint author), UNIV WASHINGTON,SCH DENT,DEPT ORAL BIOL,SEATTLE,WA 98195, USA. FU NICHD NIH HHS [HD-12629]; NIDCR NIH HHS [DE-09812]; NINDS NIH HHS [NS-08174] NR 34 TC 17 Z9 17 U1 0 U2 0 PU AMER PHYSIOLOGICAL SOC PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 0002-9513 J9 AM J PHYSIOL JI Am. J. Physiol. PD JAN PY 1994 VL 266 IS 1 BP C58 EP C66 PN 1 PG 9 WC Physiology SC Physiology GA NA591 UT WOS:A1994NA59100007 PM 8304431 ER PT J AU BALLOU, WR AF BALLOU, WR TI CLINICAL-TRIALS OF PLASMODIUM-FALCIPARUM ERYTHROCYTIC STAGE VACCINES SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article; Proceedings Paper CT Symposium on Strategy for Plasmodium Falciparum Blood-Stage Vaccine Development and Clinical Trials, at Annual Meeting of the Amer-Soc-of-Tropical-Medicine-and-Hygiene CY NOV 19, 1992 CL SEATTLE, WA SP AMER SOC TROP MED & HYGIENE AB Efficacy trials for malaria blood-stage vaccines are currently underway in several field sites. Numerous issues surround the design and execution of such trials, and there are many opportunities for failure that have little to do with the vaccines per se. This review highlights some of the key issues to be considered by investigators designing such trials, including those that are unique to trials for erythrocytic stage vaccines. RP BALLOU, WR (reprint author), WALTER REED ARMY MED CTR,WALTER REED ARMY INST RES,DEPT IMMUNOL,DIV COMMUNICABLE DIS & IMMUNOL,WASHINGTON,DC 20307, USA. NR 4 TC 2 Z9 2 U1 0 U2 0 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PY 1994 VL 50 IS 4 SU S BP 59 EP 65 PG 7 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA NK901 UT WOS:A1994NK90100009 PM 8172333 ER PT J AU CHULAY, J MANNINO, R REEVE, P WEIDANZ, W YOUNG, J COPPEL, R DESOWITZ, R SATTERTHWAIT, A SAUL, A COHEN, J PINDER, M AF CHULAY, J MANNINO, R REEVE, P WEIDANZ, W YOUNG, J COPPEL, R DESOWITZ, R SATTERTHWAIT, A SAUL, A COHEN, J PINDER, M TI AMERICAN-SOCIETY-OF-TROPICAL-MEDICINE-AND-HYGIENE SYMPOSIUM - STRATEGY FOR PLASMODIUM-FALCIPARUM VACCINE DEVELOPMENT AND CLINICAL-TRIALS - PANEL DISCUSSION SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Discussion C1 UNIV MED & DENT NEW JERSEY, NEWARK, NJ 07103 USA. WHO, WORLD BANK, UNDP, SPECIAL PROGRAM RES & TRAINING TROP MED, CH-1211 GENEVA, SWITZERLAND. UNIV WISCONSIN, MADISON, WI USA. MEDIMMUNE INC, GAITHERSBURG, MD 20878 USA. WALTER & ELIZA HALL INST MED RES, MELBOURNE, AUSTRALIA. UNIV HAWAII, HONOLULU, HI 96822 USA. SCRIPPS RES INST, LA JOLLA, CA USA. QUEENSLAND INST MED RES, BRISBANE, QLD, AUSTRALIA. SMITH KLINE BEECHAM, RIXENSART, BELGIUM. RP CHULAY, J (reprint author), USA, MED RES INST INFECT DIS, FREDERICK, MD USA. RI Coppel, Ross/A-6626-2008 OI Coppel, Ross/0000-0002-4476-9124 NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PY 1994 VL 50 IS 4 SU S BP 66 EP 74 PG 9 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA NK901 UT WOS:A1994NK90100010 ER PT J AU GUPTA, RK RUTLEDGE, LC AF GUPTA, RK RUTLEDGE, LC TI ROLE OF REPELLENTS IN VECTOR CONTROL AND DISEASE PREVENTION SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article; Proceedings Paper CT Symposium on Prevention of Tropical Diseases: Status of New and Emerging Vector Control Strategies, at the 40th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene CY DEC 02, 1991 CL BOSTON, MA SP AMER SOC TROP MED & HYGIENE, AMER COMM MED ENTOMOL AB Repellents are an inexpensive and practical means of protection against nuisance and disease vector arthropods in conjunction with or when other control measures are not feasible. Appropriate selection of skin and/or clothing repellents along with proper wear of clothing can provide adequate protection from biting arthropods, and are available in a wide variety of forms including lotions, creams, foams, soaps, aerosols, sticks, and towellettes. A coordinated effort among different research groups associated with advances in the science of insect repellents such as mode of action information, doses of repellents to generate threshold level responses and controlled release delivery mechanisms, may help in understanding the mechanisms by which repellents work. This in turn may revolutionize the development of repellents for personal protection and their use in vector control. RP GUPTA, RK (reprint author), WALTER REED ARMY INST RES,DEPT ENTOMOL,WASHINGTON,DC 20307, USA. NR 28 TC 89 Z9 96 U1 0 U2 3 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PY 1994 VL 50 IS 6 SU S BP 82 EP 86 PG 5 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA NX799 UT WOS:A1994NX79900009 PM 8024088 ER PT B AU ANDERSEN, JM AF ANDERSEN, JM GP AMER STAT ASSOC TI Runway landing distribution and tests for normality. SO AMERICAN STATISTICAL ASSOCIATION 1994 PROCEEDINGS OF THE SECTION ON BAYESIAN STATISTICAL SCIENCE LA English DT Proceedings Paper CT ASA 1994 Winter Conference CY JAN 06-09, 1994 CL ATLANTA, GA SP Amer Stat Assoc, Sect Qual & Prod DE LANDING; AIRCRAFT; NORMALITY C1 USA,CORPS ENGINEERS,WATERWAYS EXPT STN,VICKSBURG,MS 39180. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER STATISTICAL ASSOC PI ALEXANDRIA PA 1429 DUKE ST, ALEXANDRIA, VA 22314 BN 1-883276-03-9 PY 1994 BP 150 EP 152 PG 3 WC Statistics & Probability SC Mathematics GA BE02J UT WOS:A1994BE02J00029 ER PT S AU ILIAS, AM AF ILIAS, AM BE OShay, TA Hoddinott, KB TI FUEL ISOLATION, IDENTIFICATION AND QUANTITATION FROM SOILS SO ANALYSIS OF SOILS CONTAMINATED WITH PETROLEUM CONSTITUENTS SE AMERICAN SOCIETY FOR TESTING AND MATERIALS SPECIAL TECHNICAL PUBLICATION LA English DT Proceedings Paper CT Symposium on Analysis of Soils Contaminated with Petroleum Constituents CY JUN 24, 1993 CL ATLANTA, GA SP AMER SOC TESTING & MAT, COMM D18 SOIL & ROCK, SUBCOMM D18 06 PHYSICO CHEM P, ROPERT SOIL, AMER PETR INST C1 USA,CORPS ENGINEERS,N PACIFIC DIV LAB,TROUTDALE,OR 97060. NR 0 TC 1 Z9 1 U1 2 U2 2 PU AMERICAN SOCIETY TESTING AND MATERIALS PI W CONSHOHOCKEN PA 100 BARR HARBOR DRIVE, W CONSHOHOCKEN, PA 19428-2959 SN 1071-5827 BN 0-8031-1898-8 J9 AM SOC TEST MATER PY 1994 VL 1221 BP 12 EP 26 DI 10.1520/STP12652S PG 15 WC Engineering, Chemical; Environmental Sciences; Geography; Geosciences, Multidisciplinary SC Engineering; Environmental Sciences & Ecology; Geography; Geology GA BA64E UT WOS:A1994BA64E00002 ER PT J AU SZIGETI, CL BAEUERLE, JJ MONGAN, PD AF SZIGETI, CL BAEUERLE, JJ MONGAN, PD TI ARYTENOID DISLOCATION WITH LIGHTED STYLET INTUBATION - CASE-REPORT AND RETROSPECTIVE REVIEW SO ANESTHESIA AND ANALGESIA LA English DT Note ID TRACHEAL INTUBATION C1 BROOKE ARMY MED CTR,DEPT SURG,ANESTHESIA SERV,SAN ANTONIO,TX. NR 12 TC 30 Z9 34 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0003-2999 J9 ANESTH ANALG JI Anesth. Analg. PD JAN PY 1994 VL 78 IS 1 BP 185 EP 186 PG 2 WC Anesthesiology SC Anesthesiology GA NA397 UT WOS:A1994NA39700034 PM 8267162 ER PT J AU WATSON, ME NEWMAN, RJ PAYNE, AM ABDELRAHIM, M FRANCIS, GL AF WATSON, ME NEWMAN, RJ PAYNE, AM ABDELRAHIM, M FRANCIS, GL TI THE EFFECT OF MACROPHAGE CONDITIONED MEDIA ON LEYDIG-CELL FUNCTION SO ANNALS OF CLINICAL AND LABORATORY SCIENCE LA English DT Article ID TUMOR-NECROSIS-FACTOR; NITRIC-OXIDE; FACTOR-ALPHA; GONADAL DYSFUNCTION; LUTEINIZING-HORMONE; INTERLEUKIN-1; STEROIDOGENESIS; RECEPTORS; EXPRESSION; INHIBITION AB Primary gonadal failure frequently occurs in male patients with serious illness. This has suggested that activation of the immune system may affect the endocrine function of the testis. Most previous studies have evaluated the effects of individual cytokines on testosterone (T) production but with conflicting results. The present study was performed to compare the effects on Leydig cell function of a mixture of cytokines found in macrophage conditioned media (MCM), with that of individual recombinant cytokines. The MCM was found to contain an acid stable, heat labile, 16.5 kD factor(s) which significantly decreased the production of testosterone (T), dihydrotestosterone (dHT), adenosine 3':5'-cyclic monophosphate (cAMP), and guanosine 3':5'-cyclic monophosphate (cGMP). The MCM had no effect on the specific binding of human chorionic gonadotropin (hCG) but decreased the activity of 3-beta-hydroxysteroid dehydrogenase (3-beta-HSD) (a regulated Leydig cell enzyme). Neither tumor necrosis factor cr (TNF alpha) interleukin 1 alpha (IL1 alpha), interleukin I beta (IL1 beta), interleukin 2 (IL2), interleukin 6 (IL6), or human interferon alpha,beta (IFN alpha,beta) had a similar effect. These results show that the cytokines or other factor(s) contained in MCM are potent regulators of T production, which could be important in understanding the low serum T levels associated with serious illness. C1 WALTER REED ARMY MED CTR,DEPT PEDIAT,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,DEPT CLIN INVEST,WASHINGTON,DC 20307. UNIFORMED SERV UNIV HLTH SCI,DEPT PEDIAT,BETHESDA,MD 20814. MADIGAN ARMY MED CTR,DEPT PEDIAT,TACOMA,WA 98431. NR 44 TC 18 Z9 19 U1 0 U2 0 PU INST CLINICAL SCIENCE INC PI PHILADELPHIA PA 1833 DELANCEY PLACE, PHILADELPHIA, PA 19103 SN 0091-7370 J9 ANN CLIN LAB SCI JI Ann. Clin. Lab. Sci. PD JAN-FEB PY 1994 VL 24 IS 1 BP 84 EP 95 PG 12 WC Medical Laboratory Technology SC Medical Laboratory Technology GA MU642 UT WOS:A1994MU64200009 PM 8147571 ER PT S AU COLBECK, SC AF COLBECK, SC BE Jones, SJ TI AN ERROR ANALYSIS OF THE TECHNIQUES USED IN THE MEASUREMENT OF HIGH-SPEED FRICTION ON SNOW SO ANNALS OF GLACIOLOGY, VOL 19, 1994: PROCEEDINGS OF THE SYMPOSIUM ON APPLIED ICE AND SNOW RESEARCH SE ANNALS OF GLACIOLOGY LA English DT Proceedings Paper CT Symposium on Applied Ice and Snow Research CY APR 18-23, 1993 CL ROVANIEMI, FINLAND SP INT GLACIOL SOC C1 USA,COLD REG RES & ENGN LAB,HANOVER,NH 03755. NR 0 TC 0 Z9 0 U1 0 U2 1 PU INT GLACIOLOGICAL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE, ENGLAND CB2 1ER SN 0260-3055 BN 0-946417-11-3 J9 ANN GLACIOL PY 1994 VL 19 BP 19 EP 24 PG 6 WC Engineering, Civil; Geology SC Engineering; Geology GA BB64A UT WOS:A1994BB64A00004 ER PT S AU JOHNSON, JB SOLIE, DJ BARRETT, SA AF JOHNSON, JB SOLIE, DJ BARRETT, SA BE Jones, SJ TI THE RESPONSE OF A SEASONAL SNOW COVER TO EXPLOSIVE LOADING SO ANNALS OF GLACIOLOGY, VOL 19, 1994: PROCEEDINGS OF THE SYMPOSIUM ON APPLIED ICE AND SNOW RESEARCH SE ANNALS OF GLACIOLOGY LA English DT Proceedings Paper CT Symposium on Applied Ice and Snow Research CY APR 18-23, 1993 CL ROVANIEMI, FINLAND SP INT GLACIOL SOC C1 USA,COLD REG RES & ENGN LAB,FT WAINWRIGHT,AK 99703. NR 0 TC 3 Z9 3 U1 0 U2 0 PU INT GLACIOLOGICAL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE, ENGLAND CB2 1ER SN 0260-3055 BN 0-946417-11-3 J9 ANN GLACIOL PY 1994 VL 19 BP 49 EP 54 PG 6 WC Engineering, Civil; Geology SC Engineering; Geology GA BB64A UT WOS:A1994BB64A00008 ER PT S AU STURM, M HOLMGREN, J AF STURM, M HOLMGREN, J BE Jones, SJ TI EFFECTS OF MICROTOPOGRAPHY ON TEXTURE, TEMPERATURE AND HEAT-FLOW IN ARCTIC AND SUB-ARCTIC SNOW SO ANNALS OF GLACIOLOGY, VOL 19, 1994: PROCEEDINGS OF THE SYMPOSIUM ON APPLIED ICE AND SNOW RESEARCH SE ANNALS OF GLACIOLOGY LA English DT Proceedings Paper CT Symposium on Applied Ice and Snow Research CY APR 18-23, 1993 CL ROVANIEMI, FINLAND SP INT GLACIOL SOC C1 USA,COLD REG RES & ENGN LAB,FT WAINWRIGHT,AK 99703. NR 0 TC 15 Z9 15 U1 0 U2 2 PU INT GLACIOLOGICAL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE, ENGLAND CB2 1ER SN 0260-3055 BN 0-946417-11-3 J9 ANN GLACIOL PY 1994 VL 19 BP 63 EP 68 PG 6 WC Engineering, Civil; Geology SC Engineering; Geology GA BB64A UT WOS:A1994BB64A00010 ER PT S AU GOW, AJ AF GOW, AJ BE Morris, EM TI POST-DRILLING RECRYSTALLIZATION OF THE BYRD-STATION DEEP ICE CORE AND ITS RELEVANCE TO CURRENT AND FUTURE DEEP-CORE DRILLING ON POLAR ICE SHEETS SO ANNALS OF GLACIOLOGY, VOL 20, 1994: PROCEEDINGS OF THE FIFTH INTERNATIONAL SYMPOSIUM ON ANTARCTIC GLACIOLOGY (VISAG) SE ANNALS OF GLACIOLOGY LA English DT Proceedings Paper CT 5th International Symposium on Antarctic Glasiology (VISAG) CY SEP 05-11, 1993 CL CAMBRIDGE, ENGLAND SP Int Glaciol Soc C1 USA,COLD REGIONS RES & ENGN LAB,HANOVER,NH 03755. NR 0 TC 3 Z9 3 U1 0 U2 1 PU INT GLACIOLOGICAL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE, ENGLAND CB2 1ER SN 0260-3055 BN 0-946417-14-8 J9 ANN GLACIOL PY 1994 VL 20 BP 231 EP 236 DI 10.3189/172756494794587005 PG 6 WC Geosciences, Multidisciplinary; Oceanography; Water Resources SC Geology; Oceanography; Water Resources GA BD16B UT WOS:A1994BD16B00037 ER PT S AU GOW, AJ GOVONI, JW AF GOW, AJ GOVONI, JW BE Morris, EM TI AN 80-YEAR RECORD OF RETREAT OF THE KOETTLITZ ICE TONGUE, MCMURDO-SOUND, ANTARCTICA SO ANNALS OF GLACIOLOGY, VOL 20, 1994: PROCEEDINGS OF THE FIFTH INTERNATIONAL SYMPOSIUM ON ANTARCTIC GLACIOLOGY (VISAG) SE ANNALS OF GLACIOLOGY LA English DT Proceedings Paper CT 5th International Symposium on Antarctic Glasiology (VISAG) CY SEP 05-11, 1993 CL CAMBRIDGE, ENGLAND SP Int Glaciol Soc C1 USA,COLD REG RES & ENGN LAB,HANOVER,NH 03755. NR 0 TC 3 Z9 3 U1 0 U2 0 PU INT GLACIOLOGICAL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE, ENGLAND CB2 1ER SN 0260-3055 BN 0-946417-14-8 J9 ANN GLACIOL PY 1994 VL 20 BP 237 EP 241 DI 10.3189/172756494794587249 PG 5 WC Geosciences, Multidisciplinary; Oceanography; Water Resources SC Geology; Oceanography; Water Resources GA BD16B UT WOS:A1994BD16B00038 ER PT J AU DOLIGALSKI, TL SMITH, CR WALKER, JDA AF DOLIGALSKI, TL SMITH, CR WALKER, JDA TI VORTEX INTERACTIONS WITH WALLS SO ANNUAL REVIEW OF FLUID MECHANICS LA English DT Review DE UNSTEADY SEPARATION; DYNAMIC STALL; TURBULENCE ID BOUNDARY-LAYER SEPARATION; INSTANTANEOUS PRESSURE FIELDS; UNSTEADY-FLOW; HAIRPIN VORTICES; DYNAMIC STALL; FREE-SURFACE; RECTILINEAR VORTEX; PITCHING AIRFOIL; EDGE INTERACTION; LEADING-EDGE C1 LEHIGH UNIV,DEPT MECH ENGN & MECH,BETHLEHEM,PA 18015. RP DOLIGALSKI, TL (reprint author), USA,RES OFF,RES TRIANGLE PK,NC 27709, USA. NR 106 TC 194 Z9 199 U1 1 U2 18 PU ANNUAL REVIEWS INC PI PALO ALTO PA 4139 EL CAMINO WAY, PO BOX 10139, PALO ALTO, CA 94303-0139 SN 0066-4189 J9 ANNU REV FLUID MECH JI Annu. Rev. Fluid Mech. PY 1994 VL 26 BP 573 EP 616 DI 10.1146/annurev.fluid.26.1.573 PG 44 WC Mechanics; Physics, Fluids & Plasmas SC Mechanics; Physics GA MT017 UT WOS:A1994MT01700018 ER PT J AU BUCKHEIT, RW WHITE, EL GERMANYDECKER, J ALLEN, LB ROSS, LJ SHANNON, WM JANSSEN, PAJ CHIRIGOS, MA AF BUCKHEIT, RW WHITE, EL GERMANYDECKER, J ALLEN, LB ROSS, LJ SHANNON, WM JANSSEN, PAJ CHIRIGOS, MA TI CELL-BASED AND BIOCHEMICAL-ANALYSIS OF THE ANTI-HIV ACTIVITY OF COMBINATIONS OF 3'-AZIDO-3'-DEOXYTHYMIDINE AND ANALOGS OF TIBO SO ANTIVIRAL CHEMISTRY & CHEMOTHERAPY LA English DT Article ID IMMUNODEFICIENCY-VIRUS TYPE-1; REVERSE-TRANSCRIPTASE INHIBITORS; DNA POLYMERASE-ALPHA; ANTIVIRAL ACTIVITY; THYMIDINE 5'-TRIPHOSPHATE; NONNUCLEOSIDE INHIBITORS; ZIDOVUDINE AZT; DERIVATIVES; REPLICATION; INVITRO AB The toxicity of 3'-azido-3'-deoxythymidine (AZT) and the appearance of drug-resistant mutants in patients treated with AZT emphasizes the critical importance of the development of alternative strategies for the therapy of AIDS patients. Combination antiviral chemotherapy provides an attractive therapeutic strategy since the dose of the individual agents may be lowered to reduce toxicity and the use of two potent antiviral agents may limit the development of drug resistance. Two analogues of tetrahydro-imidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-thione (TIBO) potently and selectively inhibit the replication of HIV-1 in cell culture. In combination with AZT, either of the two TIBO compounds, R82913 and R86183, was highly synergistic in cell culture against HIV-1. However, in biochemical enzyme inhibition assays, utilizing recombinant HIV-1 reverse transcriptase, synergy was not detected at the enzymatic level. These results suggest that one of these two known inhibitors of HIV-1 reverse transcriptase may have a secondary mechanism of action distinct from inhibition of the reverse transcriptase. C1 JANSSEN RES FDN,BEERSE,BELGIUM. USA,MED RES INST INFECT DIS,FREDERICK,MD 21702. SO RES INST,BIRMINGHAM,AL 35255. NR 40 TC 22 Z9 23 U1 0 U2 0 PU BLACKWELL SCIENCE LTD PI OXFORD PA OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL SN 0956-3202 J9 ANTIVIR CHEM CHEMOTH JI Antivir. Chem. Chemother. PD JAN PY 1994 VL 5 IS 1 BP 35 EP 42 PG 8 WC Biochemistry & Molecular Biology; Pharmacology & Pharmacy; Virology SC Biochemistry & Molecular Biology; Pharmacology & Pharmacy; Virology GA MP256 UT WOS:A1994MP25600006 ER PT J AU SMITH, KJ SKELTON, HG DRABICK, JJ MCCARTHY, WF LEDSKY, R WAGNER, KF AF SMITH, KJ SKELTON, HG DRABICK, JJ MCCARTHY, WF LEDSKY, R WAGNER, KF TI HYPEREOSINOPHILIA SECONDARY TO IMMUNODYSREGULATION IN PATIENTS WITH HIV-1 DISEASE SO ARCHIVES OF DERMATOLOGY LA English DT Letter ID ANTIGEN; AIDS C1 USN,ARMED FORCES INST PATHOL,DEPT DERMATOL,WASHINGTON,DC 20350. RP SMITH, KJ (reprint author), USA,WASHINGTON,DC 20310, USA. NR 9 TC 36 Z9 36 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0003-987X J9 ARCH DERMATOL JI Arch. Dermatol. PD JAN PY 1994 VL 130 IS 1 BP 119 EP 121 DI 10.1001/archderm.130.1.119 PG 3 WC Dermatology SC Dermatology GA MR518 UT WOS:A1994MR51800027 PM 8285733 ER PT J AU BASS, JW WEISSE, ME PLYMYER, MR MURPHY, S EBERLY, BJ AF BASS, JW WEISSE, ME PLYMYER, MR MURPHY, S EBERLY, BJ TI DECLINE OF ERYTHROMYCIN RESISTANCE OF GROUP-A BETA-HEMOLYTIC STREPTOCOCCI IN JAPAN - COMPARISON WITH WORLDWIDE REPORTS SO ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE LA English DT Article ID SUSCEPTIBILITY; PENICILLIN; PREVALENCE; INFECTIONS; PYOGENES; CENTERS AB Objective: To determine the current prevalence of erythromycin resistance and penicillin tolerance of group A beta-hemolytic streptococci (GABHS) in Japan. Research Designs: One hundred four isolates of GABHS from the civilian community in Tokyo and 101 isolates from the military population at the US Air Force Base in Yokota, Japan, were tested for erythromycin susceptibility and penicillin susceptibility and tolerance. Setting: US Army Medical Center. Results: Of the Japanese civilian isolates, two were moderately susceptible and none were resistant to erythromycin; of the military isolates, none were moderately susceptible and one was resistant, for an overall resistance rate of 0.49%. All isolates were exquisitely susceptible to penicillin, and no evidence of penicillin tolerance was found. Conclusion: Comparison with similar studies world=wide shows that erythromycin susceptibility of GABHS in Japan is now among the lowest in the world, while just over a decade ago it was the highest. These observations mandate constant monitoring of erythromycin resistance of GABHS wherever this drug is used to treat patients with infections due to this organism. C1 USAF HOSP,PEDIAT SERV,YOKOTA,JAPAN. TRIPLER ARMY MED CTR,DEPT PATHOL,HONOLULU,HI 96859. RP BASS, JW (reprint author), TRIPLER ARMY MED CTR,DEPT PEDIAT,POB 330,HONOLULU,HI 96859, USA. NR 32 TC 35 Z9 35 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 1072-4710 J9 ARCH PEDIAT ADOL MED JI Arch. Pediatr. Adolesc. Med. PD JAN PY 1994 VL 148 IS 1 BP 67 EP 71 PG 5 WC Pediatrics SC Pediatrics GA ND428 UT WOS:A1994ND42800015 PM 8143015 ER PT J AU NIKLASSON, B HELLSTEN, G LEDUC, J AF NIKLASSON, B HELLSTEN, G LEDUC, J TI HEMORRHAGIC-FEVER WITH RENAL SYNDROME - A STUDY OF SEQUELAE FOLLOWING NEPHROPATHIA-EPIDEMICA SO ARCHIVES OF VIROLOGY LA English DT Article ID SWEDEN; DISEASE; VIRUS; HANTAVIRUS; INFECTION; ANTIBODY; AGENT; RATS AB Sequelae following Nephropathia epidemica (NE) were investigated in 792 individuals living in an endemic area of Sweden. Volunteers were tested for presence of Puumala (PUU) virus specific IgG antibodies in serum, as well as several parameters linked with renal dysfunction and cardiovascular disease (systolic and diastolic blood pressure, ECG, BMI, total cholesterol and serum creatinine). No differences were seen in any of the variables tested between PUU virus antibody positive (n = 110) and negative individuals (n = 682). In addition, the blood pressure was measured in 62 serologically confirmed patients diagnosed with clinical NE 2-6 years previously. One patient with moderate hypertension was found. C1 NATL DEF RES ESTAB,UMEA,SWEDEN. PRIMARY HLTH CARE CTR,NORSJO,SWEDEN. USA,MED RES INST INFECT DIS,FREDERICK,MD. RP NIKLASSON, B (reprint author), SWEDISH INST INFECT DIS CONTROL,S-10521 STOCKHOLM,SWEDEN. NR 24 TC 24 Z9 25 U1 1 U2 1 PU SPRINGER-VERLAG WIEN PI VIENNA PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 VIENNA, AUSTRIA SN 0304-8608 J9 ARCH VIROL JI Arch. Virol. PY 1994 VL 137 IS 3-4 BP 241 EP 247 DI 10.1007/BF01309472 PG 7 WC Virology SC Virology GA PE576 UT WOS:A1994PE57600003 PM 7944947 ER PT J AU PURI, B HENCHAL, EA BURANS, J PORTER, KR NELSON, W WATTS, DM HAYES, CG AF PURI, B HENCHAL, EA BURANS, J PORTER, KR NELSON, W WATTS, DM HAYES, CG TI A RAPID METHOD FOR DETECTION AND IDENTIFICATION OF FLAVIVIRUSES BY POLYMERASE CHAIN-REACTION AND NUCLEIC-ACID HYBRIDIZATION SO ARCHIVES OF VIROLOGY LA English DT Article ID NUCLEOTIDE-SEQUENCE; INDIRECT IMMUNOFLUORESCENCE; MONOCLONAL-ANTIBODIES; VIRUS; DENGUE; PROTEINS; DIAGNOSIS; GENOME; BLOOD; RNA AB A polymerase chain reaction (PCR) technique was developed and evaluated for the detection of flaviviruses. A set of sense and antisense oligomeric DNA primers were constructed from nucleotide sequences of the conserved region of the genome of several different flaviviruses. Virus specific complementary DNA (cDNA) was prepared by reverse transcription of total RNA extracted from infected cell cultures. Amplified cDNA was identifed by nucleic acid hybridization with specific oligomeric internal probes. Various conditions, such as number of cycles and annealing temperature were examined to optimize the detection of viral RNAs from infected cell cultures. Slot blot hybridization with a radioative probe was used to evaluate the sensitivity of PCR amplification. The PCR amplified RNA sequences of dengue 2 (DEN-2), West Nile (WN), St. Louis encephalitis (SLE) and Kunjin (KUN) virus and detected 0.1 to 1 pg of viral RNA. Japanese encephalitis (JE), Yellow Fever virus (YF), DEN-1, 3, and 4 viruses were not amplified. The more frequent occurrence of mismatches in the 3' primer binding site may explain the failure to amplify cDNA of these viruses. C1 GEOCENTERS INC,FT WASHINGTON,MD. WALTER REED ARMY INST RES,DEPT VIROL,WASHINGTON,DC. RP PURI, B (reprint author), NMRI,IDTA,MAIL STOP 7,8901 WISCONSIN AVE,BETHESDA,MD 20889, USA. NR 23 TC 20 Z9 21 U1 0 U2 2 PU SPRINGER-VERLAG WIEN PI VIENNA PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 VIENNA, AUSTRIA SN 0304-8608 J9 ARCH VIROL JI Arch. Virol. PY 1994 VL 134 IS 1-2 BP 29 EP 37 DI 10.1007/BF01379104 PG 9 WC Virology SC Virology GA MP883 UT WOS:A1994MP88300003 PM 8279959 ER PT J AU KURANE, I ROTHMAN, AL LIVINGSTON, PG GREEN, S GAGNON, SJ JANUS, J INNIS, BL NIMMANNITYA, S NISALAK, A ENNIS, FA AF KURANE, I ROTHMAN, AL LIVINGSTON, PG GREEN, S GAGNON, SJ JANUS, J INNIS, BL NIMMANNITYA, S NISALAK, A ENNIS, FA TI IMMUNOPATHOLOGIC MECHANISMS OF DENGUE HEMORRHAGIC-FEVER AND DENGUE SHOCK SYNDROME SO ARCHIVES OF VIROLOGY LA English DT Article; Proceedings Paper CT 3rd International Symposium on Positive-Strand RNA Viruses CY SEP, 1992 CL CLEARWATER, FL ID INTERFERON GAMMA-PRODUCTION; T-CELL CLONES; MONONUCLEAR PHAGOCYTES; VIRUS; LYMPHOCYTES; INFECTION; RECEPTOR; CD8 AB Dengue virus infections are a major cause of morbidity and mortality in tropical and subtropical areas of the world. The immunopathological mechanisms that result in severe complications of dengue virus infection, i.e. dengue hemorrhagic fever (DHF), are important to determine. Primary dengue virus infections induce serotype-specific and serotype-cross-reactive, CD4+ and CD8+ memory cytotoxic T lymphocytes (CTL). In secondary infections with a virus of a different serotype from that which caused primary infections, the presence of cross-reactive non-neutralizing antibodies results in an increased number of infected monocytes by dengue virus - antibody complexes. This in turn results in marked activation of serotype cross-reactive CD4+ and CD8+ memory CTL. We hypothesize that the rapid release of cytokines and chemical mediators caused by T cell activation and by CTL-mediated lysis of dengue virus-infected monocytes triggers the plasma leakage and hemorrhage that occurs in DHF. C1 ARMED FORCES RES INST MED SCI,DEPT VIROL,BANGKOK,THAILAND. RP KURANE, I (reprint author), UNIV MASSACHUSETTS,MED CTR,DEPT MED,DIV INFECT DIS & IMMUNOL,55 LAKE AVE,WORCESTER,MA 01655, USA. NR 19 TC 4 Z9 5 U1 1 U2 1 PU SPRINGER-VERLAG WIEN PI VIENNA PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 VIENNA, AUSTRIA SN 0304-8608 J9 ARCH VIROL JI Arch. Virol. PY 1994 SU 9 BP 59 EP 64 PG 6 WC Virology SC Virology GA NQ963 UT WOS:A1994NQ96300008 ER PT J AU DAVIS, NL GRIEDER, FB SMITH, JF GREENWALD, GF VALENSKI, ML SELLON, DC CHARLES, PC JOHNSTON, RE AF DAVIS, NL GRIEDER, FB SMITH, JF GREENWALD, GF VALENSKI, ML SELLON, DC CHARLES, PC JOHNSTON, RE TI A MOLECULAR-GENETIC APPROACH TO THE STUDY OF VENEZUELAN EQUINE ENCEPHALITIS-VIRUS PATHOGENESIS SO ARCHIVES OF VIROLOGY LA English DT Article; Proceedings Paper CT 3rd International Symposium on Positive-Strand RNA Viruses CY SEP, 1992 CL CLEARWATER, FL ID TRINIDAD DONKEY STRAIN; ATTENUATING MUTATIONS; STRUCTURAL PROTEINS; E2-GLYCOPROTEIN; TC-83 AB Viral pathogenesis can be described as a series of steps, analogous to a biochemical pathway, whose endpoint is disease of the infected host. Distinct viral functions may be critical at each required step. Our genetic approach is to use Venezuelan equine encephalitis virus (VEE) mutants blocked at different steps to delineate the process of pathogenesis. A full-length cDNA clone of a virulent strain of VEE was used as a template for in vitro mutagenesis to produce attenuated single-site mutants. The spread of molecularly cloned parent or mutant viruses in the mouse was monitored by infectivity, immunocytochemistry, in situ hybridization and histopathology. Virulent VEE spread through the lymphatic system, produced viremia and replicated in several visceral organs. As virus was being cleared from these sites, it began to appear in the brain, frequently beginning in the olfactory tracts. A single-site mutant in the E2 glycoprotein appeared to block pathogenesis at a very early step, and required a reversion mutation to spread beyond the site of inoculation. The feasibility of combining attenuating mutations to produce a stable VEE vaccine strain has been demonstrated using three E2 mutations. C1 USA,INFECT DIS RES INST,FREDERICK,MD. RP DAVIS, NL (reprint author), UNIV N CAROLINA,SCH MED,DEPT MICROBIOL & IMMUNOL,CB NO 7290,CHAPEL HILL,NC 27599, USA. FU NIAID NIH HHS [AI22186]; NINDS NIH HHS [NS26681] NR 17 TC 9 Z9 10 U1 0 U2 0 PU SPRINGER-VERLAG WIEN PI VIENNA PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 VIENNA, AUSTRIA SN 0304-8608 J9 ARCH VIROL JI Arch. Virol. PY 1994 SU 9 BP 99 EP 109 PG 11 WC Virology SC Virology GA NQ963 UT WOS:A1994NQ96300012 PM 8032286 ER PT B AU Murray, BC AF Murray, BC GP ASSOC STATE DAM SAFETY OFFICIALS TI Serious seepage problems at McAlpine locks and dam lead to concrete cutoff wall remediation SO ASDSO 1994 ANNUAL CONFERENCE PROCEEDINGS - DAM SAFETY '94, AND SUPPLEMENT LA English DT Proceedings Paper CT 1994 Annual Conference of the Association-of-State-Dam-Safety-Officials - Dam Safety 94 CY SEP 11-14, 1994 CL BOSTON, MA SP Assoc State Dam Safety Officials C1 USA,CORPS ENGINEERS,LOUISVILLE,KY. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ASSOC STATE DAM SAFETY OFFICIALS PI LEXINGTON PA 450 OLD EAST VINE, 2ND FLOOR, LEXINGTON, KY 40507 PY 1994 BP 187 EP 198 PG 12 WC Engineering, Civil; Water Resources SC Engineering; Water Resources GA BE71Y UT WOS:A1994BE71Y00015 ER PT B AU Klaus, MK AF Klaus, MK GP ASSOC STATE DAM SAFETY OFFICIALS TI Seepage analysis of Sardis Dam under PMF conditions SO ASDSO 1994 ANNUAL CONFERENCE PROCEEDINGS - DAM SAFETY '94, AND SUPPLEMENT LA English DT Proceedings Paper CT 1994 Annual Conference of the Association-of-State-Dam-Safety-Officials - Dam Safety 94 CY SEP 11-14, 1994 CL BOSTON, MA SP Assoc State Dam Safety Officials C1 USA,CORPS ENGINEERS,VICKSBURG,MS 39180. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ASSOC STATE DAM SAFETY OFFICIALS PI LEXINGTON PA 450 OLD EAST VINE, 2ND FLOOR, LEXINGTON, KY 40507 PY 1994 BP 469 EP 477 PG 9 WC Engineering, Civil; Water Resources SC Engineering; Water Resources GA BE71Y UT WOS:A1994BE71Y00039 ER PT J AU POST, MJ GLAES, T MATTA, J SOMMERVILLE, D EINFELD, W AF POST, MJ GLAES, T MATTA, J SOMMERVILLE, D EINFELD, W TI A LIDAR TECHNIQUE TO QUANTIFY SURFACE DEPOSITION FROM ATMOSPHERIC RELEASES OF BULK LIQUIDS SO ATMOSPHERIC ENVIRONMENT LA English DT Article DE LIDAR; DISPERSION; SPRAYING; DEPOSITION AB We show that a scanning, pulsed lidar can be used to quantify the time history and areal concentration of mass deposited on the ground from an elevated release of bulk liquid. Aircraft measurements, witness card depositions and evaporative modeling crudely support results from analysed lidar data. C1 USA,CTR CHEM RES DEV & ENGN,ABERDEEN PROVING GROUND,MD 21010. SANDIA NATL LABS,DIV APPL ATMOSPHER RES,ALBUQUERQUE,NM 87185. RP POST, MJ (reprint author), NOAA,WAVE PROPAGAT LAB,325 BROADWAY,BOULDER,CO 80303, USA. NR 4 TC 0 Z9 0 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 1352-2310 J9 ATMOS ENVIRON JI Atmos. Environ. PD JAN PY 1994 VL 28 IS 2 BP 257 EP 264 DI 10.1016/1352-2310(94)90100-7 PG 8 WC Environmental Sciences; Meteorology & Atmospheric Sciences SC Environmental Sciences & Ecology; Meteorology & Atmospheric Sciences GA NR212 UT WOS:A1994NR21200009 ER PT B AU CHRISTENSEN, SD MERROW, CN DESHA, MS WONG, A WILSON, MW BUTLER, J AF CHRISTENSEN, SD MERROW, CN DESHA, MS WONG, A WILSON, MW BUTLER, J BE Flood, WA Miller, WB TI UV FLUORESCENCE LIDAR DETECTION OF BIOAEROSOLS SO ATMOSPHERIC PROPAGATION AND REMOTE SENSING III SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Atmospheric Propagation and Remote Sensing III CY APR 05-07, 1994 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,EDGEWOOD RES,CTR DEV & ENGN,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 1 Z9 2 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1526-X J9 P SOC PHOTO-OPT INS PY 1994 VL 2222 BP 228 EP 237 DI 10.1117/12.177988 PG 10 WC Remote Sensing; Optics SC Remote Sensing; Optics GA BA83V UT WOS:A1994BA83V00026 ER PT B AU SMITH, RW RICKLIN, JC CRANSTON, KE CRUNCLETON, JP AF SMITH, RW RICKLIN, JC CRANSTON, KE CRUNCLETON, JP BE Flood, WA Miller, WB TI COMPARISON OF A MODEL DESCRIBING PROPAGATION THROUGH OPTICAL TURBULENCE (PROTURB) WITH FIELD DATA SO ATMOSPHERIC PROPAGATION AND REMOTE SENSING III SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Atmospheric Propagation and Remote Sensing III CY APR 05-07, 1994 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,FT BELVOIR METEOROL TEAM,FT BELVOIR,VA 22060. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1526-X J9 P SOC PHOTO-OPT INS PY 1994 VL 2222 BP 780 EP 789 DI 10.1117/12.177955 PG 10 WC Remote Sensing; Optics SC Remote Sensing; Optics GA BA83V UT WOS:A1994BA83V00085 ER PT B AU YEE, YP CIONCO, RM SUTHERLAND, RA AF YEE, YP CIONCO, RM SUTHERLAND, RA BE Flood, WA Miller, WB TI OPTICAL TURBULENCE ESTIMATES OVER COMPLEX TERRAIN USING A HIGH-RESOLUTION WIND MODEL SO ATMOSPHERIC PROPAGATION AND REMOTE SENSING III SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Atmospheric Propagation and Remote Sensing III CY APR 05-07, 1994 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,RES LAB,WHITE SANDS MISSILE RANGE,NM 88002. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1526-X J9 P SOC PHOTO-OPT INS PY 1994 VL 2222 BP 827 EP 838 DI 10.1117/12.177960 PG 12 WC Remote Sensing; Optics SC Remote Sensing; Optics GA BA83V UT WOS:A1994BA83V00090 ER PT J AU Rubel, GO Seaver, M AF Rubel, G. O. Seaver, M. TI The temperature of an evaporating water droplet with a monolayer coating: comparison of experiment and theory SO ATMOSPHERIC RESEARCH LA English DT Article AB An analytic solution is presented for the steady state temperature of an evaporating water droplet with a monolayer coating. The solution is based on the flux matching arguments of Fuchs where the continuum flux is matched to the kinetic flux one mean free path from the droplet surface. Theoretical temperatures are compared to experimental values measured with fluorescence thermometry for evaporating water droplets coated with hexadecanol and octadecanol monolayers. C1 [Rubel, G. O.] USA, Armament Munit & Chem Command, Chem Res Dev & Engn Ctr, Aberdeen Proving Ground, MD 21010 USA. [Seaver, M.] USN, Res Lab, Washington, DC 20375 USA. RP Rubel, GO (reprint author), USA, Armament Munit & Chem Command, Chem Res Dev & Engn Ctr, Aberdeen Proving Ground, MD 21010 USA. NR 14 TC 1 Z9 1 U1 0 U2 2 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 0169-8095 J9 ATMOS RES JI Atmos. Res. PD JAN PY 1994 VL 31 IS 1-3 SI SI BP 59 EP 69 DI 10.1016/0169-8095(94)90033-7 PG 11 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA V26DH UT WOS:000208525800005 ER PT B AU LANZEROTTI, MYD RINZLER, AG PINTO, JJ THOMSON, DJ WOLFE, A AF LANZEROTTI, MYD RINZLER, AG PINTO, JJ THOMSON, DJ WOLFE, A BE Cohen, SH Bray, MT Lightbody, ML TI FRACTURE SURFACE TOPOGRAPHY OF TNT USING ATOMIC FORCE MICROSCOPY SO ATOMIC FORCE MICROSCOPY/SCANNING TUNNELING MICROSCOPY LA English DT Proceedings Paper CT 1st US-Army-Natick-Research-Development-and-Engineering-Center Atomic Force Microscopy/Scanning Tunneling Microscopy (AFM/STM) Symposium CY JUN 08-10, 1993 CL NATICK, MA SP USA, NATICK RES DEV & ENGN CTR C1 USA,CTR ARMAMENT RES DEV & ENGN,PICATINNY ARSENAL,NJ 07806. NR 0 TC 0 Z9 0 U1 0 U2 0 PU PLENUM PRESS DIV PLENUM PUBLISHING CORP PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 BN 0-306-44890-4 PY 1994 BP 127 EP 135 PG 9 WC Biophysics; Instruments & Instrumentation; Materials Science, Characterization & Testing; Optics SC Biophysics; Instruments & Instrumentation; Materials Science; Optics GA BC72R UT WOS:A1994BC72R00013 ER PT J AU WORTZEL, LM AF WORTZEL, LM TI QUELLING THE PEOPLE - THE MILITARY SUPPRESSION OF THE BEIJING DEMOCRACY MOVEMENT - BROOK,T SO AUSTRALIAN JOURNAL OF CHINESE AFFAIRS LA English DT Book Review RP WORTZEL, LM (reprint author), USA,OFF DEPUTY CHIEF STAFF OPERAT & PLANS,WASHINGTON,DC 20310, USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU CONTEMPORARY CHINA CENTRE PI CANBERRA ACT PA RESEARCH SCH PACIFIC STUDIES, AUSTRALIAN NATL UNIV, GPO BOX 4, CANBERRA ACT, AU 2601 SN 0156-7365 J9 AUST J CHINESE AFF PD JAN PY 1994 IS 31 BP 123 EP 126 DI 10.2307/2949905 PG 4 WC Area Studies SC Area Studies GA MQ790 UT WOS:A1994MQ79000008 ER PT B AU PHILLIPS, PJ AF PHILLIPS, PJ BE Mammone, RJ Murley, JD TI MATCHING PURSUIT FILTERS APPLIED TO FACE IDENTIFICATION SO AUTOMATIC SYSTEMS FOR THE IDENTIFICATION AND INSPECTION OF HUMANS SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Automatic Systems for the Identification and Inspection of Humans CY JUL 28-29, 1994 CL SAN DIEGO, CA SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,RES LAB,FT BELVOIR,VA 22060. NR 0 TC 2 Z9 2 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1601-0 J9 P SOC PHOTO-OPT INS PY 1994 VL 2277 BP 2 EP 11 PG 10 WC Computer Science, Artificial Intelligence; Optics SC Computer Science; Optics GA BB97C UT WOS:A1994BB97C00001 ER PT J AU WELKOS, S OBRIEN, A AF WELKOS, S OBRIEN, A TI DETERMINATION OF MEDIAN LETHAL AND INFECTIOUS DOSES IN ANIMAL-MODEL SYSTEMS SO BACTERIAL PATHOGENESIS, PT A SE METHODS IN ENZYMOLOGY LA English DT Review ID COMPUTER-PROGRAM; PROBIT; LD50 C1 UNIFORMED SERV UNIV HLTH SCI,DEPT MICROBIOL,BETHESDA,MD 20814. RP WELKOS, S (reprint author), USA,MED RES INST INFECT DIS,DIV BACTERIOL,FREDERICK,MD 21072, USA. FU PHS HHS [AL-20148-9] NR 20 TC 45 Z9 47 U1 0 U2 0 PU ACADEMIC PRESS INC PI SAN DIEGO PA 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 SN 0076-6879 J9 METHOD ENZYMOL JI Methods Enzymol. PY 1994 VL 235 BP 29 EP 39 PG 11 WC Biochemical Research Methods; Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA BA88R UT WOS:A1994BA88R00002 PM 8057901 ER PT J AU KOPECKO, DJ AF KOPECKO, DJ TI EXPERIMENTAL KERATOCONJUNCTIVITIS (SERENY) ASSAY SO BACTERIAL PATHOGENESIS, PT A SE METHODS IN ENZYMOLOGY LA English DT Review ID SHIGELLA RP KOPECKO, DJ (reprint author), WALTER REED ARMY MED CTR,WALTER REED ARMY INST RES,DEPT BACTERIAL DIS,WASHINGTON,DC 20307, USA. NR 17 TC 6 Z9 6 U1 1 U2 1 PU ACADEMIC PRESS INC PI SAN DIEGO PA 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 SN 0076-6879 J9 METHOD ENZYMOL JI Methods Enzymol. PY 1994 VL 235 BP 39 EP 47 PG 9 WC Biochemical Research Methods; Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA BA88R UT WOS:A1994BA88R00003 ER PT J AU APICELLA, MA GRIFFISS, JML SCHNEIDER, H AF APICELLA, MA GRIFFISS, JML SCHNEIDER, H TI ISOLATION AND CHARACTERIZATION OF LIPOPOLYSACCHARIDES, LIPOOLIGOSACCHARIDES, AND LIPID-A SO BACTERIAL PATHOGENESIS, PT A SE METHODS IN ENZYMOLOGY LA English DT Review ID NEISSERIA-GONORRHOEAE LIPOOLIGOSACCHARIDES; POLYACRYLAMIDE GEL-ELECTROPHORESIS; STRUCTURAL CHARACTERIZATION; HEMOPHILUS-INFLUENZAE; HETEROGENEITY; MENINGITIDIS; STRAINS; PROTEINS C1 UNIV CALIF SAN FRANCISCO,DEPT LAB MED,SAN FRANCISCO,CA 94121. WALTER REED ARMY MED CTR,WALTER REED ARMY INST RES,DEPT BACTERIAL DIS,WASHINGTON,DC 20307. RP APICELLA, MA (reprint author), UNIV IOWA,COLL MED,DEPT MICROBIOL,IOWA CITY,IA 52242, USA. NR 34 TC 101 Z9 101 U1 2 U2 13 PU ACADEMIC PRESS INC PI SAN DIEGO PA 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 SN 0076-6879 J9 METHOD ENZYMOL JI Methods Enzymol. PY 1994 VL 235 BP 242 EP 252 PG 11 WC Biochemical Research Methods; Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA BA88R UT WOS:A1994BA88R00019 PM 8057898 ER PT J AU DEAL, CD HOWARD, HC AF DEAL, CD HOWARD, HC TI SOLID-PHASE BINDING OF MICROORGANISMS TO GLYCOLIPIDS AND PHOSPHOLIPIDS SO BACTERIAL PATHOGENESIS, PT B SE METHODS IN ENZYMOLOGY LA English DT Review ID THIN-LAYER CHROMATOGRAMS; PSEUDOMONAS-AERUGINOSA; NEISSERIA-GONORRHOEAE; EXOENZYME-S; RECEPTORS; GANGLIOSIDES; ADHESION C1 AMER UNIV CARRIBEAN,SCH MED,PLYMOUTH,W IND ASSOC ST. RP DEAL, CD (reprint author), WALTER REED ARMY INST RES,DEPT BACTERIAL DIS,WASHINGTON,DC 20307, USA. NR 16 TC 1 Z9 1 U1 0 U2 0 PU ACADEMIC PRESS INC PI SAN DIEGO PA 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 SN 0076-6879 J9 METHOD ENZYMOL JI Methods Enzymol. PY 1994 VL 236 BP 346 EP 353 PG 8 WC Biochemical Research Methods; Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA BA88S UT WOS:A1994BA88S00024 PM 7968621 ER PT J AU ELSINGHORST, EA AF ELSINGHORST, EA TI MEASUREMENT OF INVASION BY GENTAMICIN RESISTANCE SO BACTERIAL PATHOGENESIS, PT B SE METHODS IN ENZYMOLOGY LA English DT Review ID EPITHELIAL-CELL INVASION; SALMONELLA-TYPHIMURIUM; ESCHERICHIA-COLI; HELA-CELLS; EXPRESSION; INFECTION; VIRULENCE; GENES RP ELSINGHORST, EA (reprint author), WALTER REED ARMY INST RES,DEPT BACTERIAL DIS,WASHINGTON,DC 20307, USA. NR 26 TC 221 Z9 223 U1 3 U2 11 PU ACADEMIC PRESS INC PI SAN DIEGO PA 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 SN 0076-6879 J9 METHOD ENZYMOL JI Methods Enzymol. PY 1994 VL 236 BP 405 EP 420 PG 16 WC Biochemical Research Methods; Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA BA88S UT WOS:A1994BA88S00028 PM 7968625 ER PT S AU BROWN, JE RENFRO, J MONTGOMERY, V SAKURAI, J AF BROWN, JE RENFRO, J MONTGOMERY, V SAKURAI, J BE Freer, J Aitken, R Alouf, JE Boulnois, G Falmagne, P Fehrenbach, F Montecucco, C Piemont, Y Rappuoli, R Wadstrom, T Witholt, B TI MONOCLONAL-ANTIBODY FOR BETA-TOXIN OF CLOSTRIDIUM-PERFRINGENS TYPE-C RECOGNIZES MULTIMERIC TOXIN AGGREGATES SO BACTERIAL PROTEIN TOXINS: SIXTH EUROPEAN WORKSHOP SE ZENTRALBLATT FUR BAKTERIOLOGIE : SUPPLEMENT LA English DT Proceedings Paper CT 6th European Workshop on Bacterial Protein Toxins CY JUN 27-JUL 02, 1993 CL STIRLING, SCOTLAND SP FEDERAT EUROPEAN MICROBIOL SOC C1 USA,MED RES INST INFECT DIS,FREDERICK,MD 21702. NR 0 TC 0 Z9 0 U1 0 U2 1 PU GUSTAV FISCHER VERLAG PI STUTTGART 70 PA WOLLGRASWEG 49, W-7000 STUTTGART 70, GERMANY SN 0172-5629 BN 3-437-11535-9 J9 ZBL BAKT S PY 1994 VL 24 BP 506 EP 507 PG 2 WC Biochemistry & Molecular Biology; Microbiology; Toxicology SC Biochemistry & Molecular Biology; Microbiology; Toxicology GA BA51D UT WOS:A1994BA51D00106 ER PT S AU MIDDLEBROOK, JL LAPENOTIERE, H CLAYTON, M BROWN, D AF MIDDLEBROOK, JL LAPENOTIERE, H CLAYTON, M BROWN, D BE Freer, J Aitken, R Alouf, JE Boulnois, G Falmagne, P Fehrenbach, F Montecucco, C Piemont, Y Rappuoli, R Wadstrom, T Witholt, B TI DEVELOPMENT OF A MOLECULARLY ENGINEERED VACCINE FOR BOTULINUM TOXIN SO BACTERIAL PROTEIN TOXINS: SIXTH EUROPEAN WORKSHOP SE ZENTRALBLATT FUR BAKTERIOLOGIE : SUPPLEMENT LA English DT Proceedings Paper CT 6th European Workshop on Bacterial Protein Toxins CY JUN 27-JUL 02, 1993 CL STIRLING, SCOTLAND SP FEDERAT EUROPEAN MICROBIOL SOC C1 USA,MED RES INST INFECT DIS,DIV TOXINOL,FREDERICK,MD 21702. NR 0 TC 0 Z9 0 U1 0 U2 0 PU GUSTAV FISCHER VERLAG PI STUTTGART 70 PA WOLLGRASWEG 49, W-7000 STUTTGART 70, GERMANY SN 0172-5629 BN 3-437-11535-9 J9 ZBL BAKT S PY 1994 VL 24 BP 531 EP 532 PG 2 WC Biochemistry & Molecular Biology; Microbiology; Toxicology SC Biochemistry & Molecular Biology; Microbiology; Toxicology GA BA51D UT WOS:A1994BA51D00117 ER PT J AU BROWN, DO LU, ST ELSON, EC AF BROWN, DO LU, ST ELSON, EC TI CHARACTERISTICS OF MICROWAVE EVOKED BODY MOVEMENTS IN MICE SO BIOELECTROMAGNETICS LA English DT Article DE HIGH PEAK POWER MICROWAVES; RESPONSE LATENCY; SUBCUTANEOUS TEMPERATURE ID ELECTROMAGNETIC-FIELDS; RATS AB Microwave evoked body movements were studied in mice. A resonant cavity was used to provide head and neck exposure of the mouse to pulsed and gated continuous wave (CW) 1.25 GHz microwaves. No difference in response to pulsed and gated CW stimuli of equal average power was found. The incidence of the microwave evoked body movements increased proportionally with specific absorption (dose) when the whole-body average specific absorption rate was at a constant level (7300 W/kg). Under a constant average specific absorption rate, the response incidence reached a plateau at 0.9 kJ/kg. For doses higher than 0.9 kJ/kg, response incidence was proportional to the specific absorption rate and reached a plateau at 900 W/kg. Body movements could be evoked by a single microwave pulse. The lowest whole-body specific absorption (SA) tested was 0.18 kJ/kg, and the corresponding brain SA was 0.29 kl/kg. Bulk heating potentials of these SAs were less than 0.1-degrees-C. For doses higher than 0.9 kJ/kg, the response incidence was also proportional to subcutaneous temperature increment and subcutaneous heating rate. The extrapolated absolute thresholds (0% incidence) were 1.21-degrees-C temperature increment and 0.24-degrees-C/s heating rate. Due to high subcutaneous heating rates, these microwaves must be perceived by the mouse as an intense thermal sensation but not a pain sensation because the temperature increment was well below the threshold for thermal pain. Results of the present study should be considered in promulgation of personnel protection guideline against high peak power but low average power microwaves. (C) 1994 Wiley-Li,s, Inc. C1 WALTER REED ARMY INST RES,DEPT MICROWAVE RES,WASHINGTON,DC 20307. RP BROWN, DO (reprint author), OGDEN BIOSERV CORP,6 MONTGOMERY VILLAGE AVE,SUITE 222,GAITHERSBURG,MD 20879, USA. NR 29 TC 8 Z9 8 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0197-8462 J9 BIOELECTROMAGNETICS JI Bioelectromagnetics PY 1994 VL 15 IS 2 BP 143 EP 161 DI 10.1002/bem.2250150206 PG 19 WC Biology; Biophysics SC Life Sciences & Biomedicine - Other Topics; Biophysics GA NC381 UT WOS:A1994NC38100005 PM 8024606 ER PT J AU DOYLE, RD FISHER, TR AF DOYLE, RD FISHER, TR TI NITROGEN-FIXATION BY PERIPHYTON AND PLANKTON ON THE AMAZON FLOODPLAIN AT LAKE CALADO SO BIOGEOCHEMISTRY LA English DT Article DE AMAZON FLOODPLAIN; FLOATING MEADOWS; NITROGEN FIXATION; PERIPHYTON; PLANKTON; TROPICAL LIMNOLOGY ID MAJOR IONIC SOLUTES; SALT-MARSH; ACETYLENE-REDUCTION; FRESH-WATER; MARINE ECOSYSTEMS; BASIN; PHOSPHORUS; VENEZUELA; ALGAE; PHYTOPLANKTON AB Nitrogen fixation by periphyton and plankton was measured on the Amazon floodplain using the acetylene reduction method calibrated with N-15-N2. The average ratio (+/- SD) of moles C2H4 reduced per mole N2-N fixed was 3.4 +/- 0.7, similar to other studies. Periphyton and plankton had high rates of light-dependent nitrogen fixation, with dark nitrogen fixation averaging 26% of the average rates in the light. The average daily (24 h) rates for periphyton nitrogen fixation in 1989 and 1990 were 1.79 and 0.51 mmol N2-N.m-1.d-1 respectively, which are comparable to summer rates in many temperate cyanobacterial assemblages. Nitrogen fixation was depressed at NO3- Concentrations as low as 0.5 muM, and was below detection limits at concentrations of 4 muM, which occurred during periods of river flooding. Planktonic nitrogen fixation rates were high (0.5-0.8 mmol N2-N.m-2.d-1) during the high-water and drainage phases of the annual hydrograph when the floodplain waters were draining towards the river (low NO3-), but rates were undetectable (< 0.05 mmol N2-N.m-2.d-1) when there was river flooding (high NO3-). Nitrogen fixation by periphyton and plankton in 1989-1990 accounted for approximately 8% of previously reported total annual nitrogen inputs to the floodplain at Lake Calado. C1 USA,ENGINEERS WATERWAYS EXPTL STN,LEWISVILLE AQUAT ECOSYST RES FACIL,RR 3,BOX 446,LEWISVILLE,TX 75056. RP DOYLE, RD (reprint author), UNIV MARYLAND,HORN POINT ENVIRONM LAB,CAMBRIDGE,MD 21613, USA. NR 66 TC 28 Z9 28 U1 0 U2 7 PU KLUWER ACADEMIC PUBL PI DORDRECHT PA SPUIBOULEVARD 50, PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS SN 0168-2563 J9 BIOGEOCHEMISTRY JI Biogeochemistry PY 1994 VL 26 IS 1 BP 41 EP 66 DI 10.1007/BF02180403 PG 26 WC Environmental Sciences; Geosciences, Multidisciplinary SC Environmental Sciences & Ecology; Geology GA PF772 UT WOS:A1994PF77200003 ER PT S AU FAMINI, GR WILSON, LY DEVITO, SC AF FAMINI, GR WILSON, LY DEVITO, SC BE Saleh, MA Blancato, JN Nauman, CH TI MODELING CYTOCHROME-P-450 MEDIATED ACUTE NITRILE TOXICITY USING THEORETICAL LINEAR SOLVATION ENERGY RELATIONSHIPS SO BIOMARKERS OF HUMAN EXPOSURE TO PESTICIDES SE ACS SYMPOSIUM SERIES LA English DT Article; Proceedings Paper CT Symposium on Biomarkers of Human Exposure to Pesticides, at the 204th National Meeting of the American-Chemical-Society CY AUG 23-28, 1992 CL WASHINGTON, DC SP AMER CHEM SOC, DIV AGROCHEM ID WATER PARTITION-COEFFICIENTS; PROPERTIES GOVERNING SOLUBILITIES; BIOLOGICAL MEDIA; ORGANIC NONELECTROLYTES; ALIPHATIC NITRILES; SOLVATOCHROMIC PARAMETERS; AROMATIC SOLUTES; PHYSICOCHEMICAL PROPERTIES; LIPOPHILIC CHARACTER; SOLVENT INTERACTIONS AB A theoretical linear solvation energy relationship (TLSER) model for predicting acute nitrile toxicity was developed using molecular volume, dipolarity/polarizability, hydrogen bond (molecular orbital) acidity, and electrostatic basicity terms as descriptors. It was observed that molecular orbital acidity was the most important descriptor in the model, followed by molecular volume. The predictive quality of the TLSER model appears to be equal to that of a recently reported model that uses octanol-water partition coefficients and estimated rates of alpha-hydrogen atom abstraction as descriptors. Previously reported TLSER models of toxicity have largely been confined to predicting non-specific toxicity. The results of this study suggest that TLSER models may be useful in predicting specific (mechanism-based) toxicity. C1 US EPA,OFF POLLUT PREVENT & TOX TS779,WASHINGTON,DC 20460. LA SIERRA UNIV,DEPT CHEM,RIVERSIDE,CA. USA,CHEM RES,CTR DEV & ENGN,ABERDEEN PROVING GROUND,MD 21010. NR 62 TC 2 Z9 2 U1 0 U2 1 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 SIXTEENTH ST NW, WASHINGTON, DC 20036 SN 0097-6156 BN 0-8412-2738-1 J9 ACS SYM SER PY 1994 VL 542 BP 22 EP 36 PG 15 WC Biochemistry & Molecular Biology; Chemistry, Multidisciplinary; Chemistry, Analytical; Environmental Sciences; Toxicology SC Biochemistry & Molecular Biology; Chemistry; Environmental Sciences & Ecology; Toxicology GA BZ59N UT WOS:A1994BZ59N00002 ER PT S AU ELDEFRAWI, ME ROGERS, KR ANIS, NA THOMPSON, R VALDES, JJ AF ELDEFRAWI, ME ROGERS, KR ANIS, NA THOMPSON, R VALDES, JJ BE Saleh, MA Blancato, JN Nauman, CH TI A BIOSENSOR FOR MONITORING BLOOD CHOLINESTERASES AS A BIOMARKER OF EXPOSURE TO ORGANOPHOSPHORUS ANTICHOLINESTERASE PESTICIDES SO BIOMARKERS OF HUMAN EXPOSURE TO PESTICIDES SE ACS SYMPOSIUM SERIES LA English DT Article; Proceedings Paper CT Symposium on Biomarkers of Human Exposure to Pesticides, at the 204th National Meeting of the American-Chemical-Society CY AUG 23-28, 1992 CL WASHINGTON, DC SP AMER CHEM SOC, DIV AGROCHEM ID ACETYLCHOLINE-RECEPTOR; SENSOR; ELECTRODE; IMMUNOSENSOR; ENZYME AB A fiber optic evanescent fluorosensor was developed for the rapid detection of anticholinesterases (AntiChEs) and was modified to measure cholinesterase (ChE) activities in whole blood. Quartz fibers coated with fluorescein isothiocyanate (FITC)-tagged acetylcholinesterase (AChE), detected AntiChEs by their reduction of quenching of fluorescence that was produced by protons generated during acetylcholine (ACh) hydrolysis. Blood ChE activity was detected by quenching the fluorescence of FITC bovine serum albumin immobilized on the quartz fiber. High ChE activity in blood samples produced strong fluorescence quenching and exposure to antiChEs reduced quenching. Fluorometric measurements were made in seconds to minutes by evanescent waveguide fluorometer on 200 mu l blood samples. A 2-minute rinse in Krebs buffer was sufficient to prepare the fiber for another measurement. C1 US EPA,ENVIRONM MONITORING SYST LAB,DIV EXPOSURE ASSESSMENT RES,LAS VEGAS,NV 89193. USA,CTR RES DEV & ENGN,DIV BIOTECHNOL,EDGEWOOD,MD 21010. RP ELDEFRAWI, ME (reprint author), UNIV MARYLAND,SCH MED,DEPT PHARMACOL & EXPTL THERAPEUT,BALTIMORE,MD 21201, USA. NR 27 TC 2 Z9 2 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 SIXTEENTH ST NW, WASHINGTON, DC 20036 SN 0097-6156 BN 0-8412-2738-1 J9 ACS SYM SER PY 1994 VL 542 BP 114 EP 124 PG 11 WC Biochemistry & Molecular Biology; Chemistry, Multidisciplinary; Chemistry, Analytical; Environmental Sciences; Toxicology SC Biochemistry & Molecular Biology; Chemistry; Environmental Sciences & Ecology; Toxicology GA BZ59N UT WOS:A1994BZ59N00007 ER PT S AU CIMECIOGLU, AL BALL, DH KAPLAN, DL HUANG, SH AF CIMECIOGLU, AL BALL, DH KAPLAN, DL HUANG, SH BE Alper, M Bayley, H Kaplan, D Navia, M TI PREPARATION OF 6-0-ACYL AMYLOSE DERIVATIVES SO BIOMOLECULAR MATERIALS BY DESIGN SE MATERIALS RESEARCH SOCIETY SYMPOSIUM PROCEEDINGS LA English DT Proceedings Paper CT Symposium S, Biomolecular Materials by Design CY NOV 29-DEC 03, 1993 CL BOSTON, MA SP MAT RES SOC C1 USA,NATICK RD&E CTR,DIV BIOTECHNOL,NATICK,MA 01760. NR 0 TC 4 Z9 4 U1 0 U2 0 PU MATERIALS RESEARCH SOC PI PITTSBURGH PA 9800 MCKNIGHT RD, SUITE 327, PITTSBURGH, PA 15237 SN 0272-9172 BN 1-55899-229-4 J9 MATER RES SOC SYMP P PY 1994 VL 330 BP 7 EP 12 PG 6 WC Biotechnology & Applied Microbiology; Materials Science, Ceramics; Materials Science, Coatings & Films SC Biotechnology & Applied Microbiology; Materials Science GA BB13M UT WOS:A1994BB13M00002 ER PT S AU MCGRATH, KP KAPLAN, DL AF MCGRATH, KP KAPLAN, DL BE Alper, M Bayley, H Kaplan, D Navia, M TI BIOLOGICAL SELF-ASSEMBLY - A PARADIGM FOR MATERIALS SCIENCE SO BIOMOLECULAR MATERIALS BY DESIGN SE MATERIALS RESEARCH SOCIETY SYMPOSIUM PROCEEDINGS LA English DT Proceedings Paper CT Symposium S, Biomolecular Materials by Design CY NOV 29-DEC 03, 1993 CL BOSTON, MA SP MAT RES SOC C1 USA,NATICK RD&E CTR,DIV BIOTECHNOL,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 1 PU MATERIALS RESEARCH SOC PI PITTSBURGH PA 9800 MCKNIGHT RD, SUITE 327, PITTSBURGH, PA 15237 SN 0272-9172 BN 1-55899-229-4 J9 MATER RES SOC SYMP P PY 1994 VL 330 BP 61 EP 68 PG 8 WC Biotechnology & Applied Microbiology; Materials Science, Ceramics; Materials Science, Coatings & Films SC Biotechnology & Applied Microbiology; Materials Science GA BB13M UT WOS:A1994BB13M00009 ER PT B AU COYLE, CG AF COYLE, CG BE Hinchee, RE Semprini, L Ong, SK Leeson, A TI PHENOL-INDUCED TCE DEGRADATION BY PURE AND MIXED CULTURES IN BATCH STUDIES AND CONTINUOUS-FLOW REACTORS SO BIOREMEDIATION OF CHLORINATED AND POLYCYCLIC AROMATIC HYDROCARBON COMPOUNDS LA English DT Proceedings Paper CT 2nd International Symposium on In Situ and On-Site Bioreclamation CY APR, 1993 CL SAN DIEGO, CA SP BATTELLE MEM INST C1 USA CORPS ENGINEERS,KANSAS CITY,MO 64106. NR 0 TC 3 Z9 3 U1 0 U2 0 PU LEWIS PUBLISHERS INC PI BOCA RATON PA 2000 CORPORATE BLVD NW, BOCA RATON, FL 33431 BN 0-87371-983-2 PY 1994 BP 339 EP 343 PG 5 WC Biotechnology & Applied Microbiology; Engineering, Environmental; Environmental Sciences SC Biotechnology & Applied Microbiology; Engineering; Environmental Sciences & Ecology GA BC30T UT WOS:A1994BC30T00036 ER PT B AU KIM, Y AF KIM, Y BE Yu, EY TI Multi-culturalism in Los Angeles: A personal perspective SO BLACK-KOREAN ENCOUNTER: TOWARD UNDERSTANDING AND ALLIANCE - DIALOGUE BETWEEN BLACK AND KOREAN AMERICANS IN THE AFTERMATH OF THE 1992 LOS ANGELES RIOTS LA English DT Proceedings Paper CT Symposium on Black-Korean Encounter CY MAY 22-23, 1992 CL CALIF STATE UNIV, LOS ANGELES, CA SP Inst Asian Amer & Pacific Asian Studies HO CALIF STATE UNIV C1 USA,WASHINGTON,DC. NR 0 TC 0 Z9 0 U1 0 U2 0 PU INSTITUTE ASIAN AMERICAN & PACIFIC ASIAN STUDIES PI LOS ANGELES PA CALIF STATE UNIV LOS ANGELES 5151 STATE UNIV DRIVE, LOS ANGELES, CA 90032 BN 0-941690-60-1 PY 1994 BP 4 EP 9 PG 2 WC Social Issues SC Social Issues GA BD76Y UT WOS:A1994BD76Y00002 ER PT J AU YEE, E CHAN, R KOSTENIUK, PR CHANDLER, GM BILTOFT, CA BOWERS, JF AF YEE, E CHAN, R KOSTENIUK, PR CHANDLER, GM BILTOFT, CA BOWERS, JF TI INCORPORATION OF INTERNAL FLUCTUATIONS IN A MEANDERING PLUME MODEL OF CONCENTRATION FLUCTUATIONS SO BOUNDARY-LAYER METEOROLOGY LA English DT Article AB A meandering plume model that explicitly incorporates the effects of small-scale structure in the instantaneous plume has been formulated. The model requires the specification of two physically based input parameters; namely, the meander ratio, M, which is dependent on the ratio of the meandering plume dispersion to the instantaneous relative plume dispersion and, a relative in-plume fluctuation measure, k, that is related inversely to the fluctuation intensity in relative coordinates. Simple analytical expressions for crosswind profiles of the higher moments (including the important shape parameters such as fluctuation intensity, skewness, and kurtosis) and for the concentration pdf have been derived from the model. The model has been tested against some field data sets, indicating that it can reproduce many key aspects of the observed behavior of concentration fluctuations, particularly with respect to modeling the change in shape of the concentration pdf in the crosswind direction. C1 KOSTENIUK CONSULTING LTD,SASKATOON S7H 2L9,SK,CANADA. S&J ENGN INC,SCARBOROUGH M1V 3S1,ON,CANADA. USA,MAT TEST DIRECTORATE,DIV METEOROL,DUGWAY PROVING GROUND,UT 84022. RP YEE, E (reprint author), DEF RES ESTAB SUFFIELD,BOX 4000,MEDICINE HAT T1A 8K6,AB,CANADA. NR 24 TC 20 Z9 21 U1 0 U2 2 PU KLUWER ACADEMIC PUBL PI DORDRECHT PA SPUIBOULEVARD 50, PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS SN 0006-8314 J9 BOUND-LAY METEOROL JI Bound.-Layer Meteor. PD JAN PY 1994 VL 67 IS 1-2 BP 11 EP 39 DI 10.1007/BF00705506 PG 29 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA MY006 UT WOS:A1994MY00600002 ER PT J AU GENOVESE, RF MORETON, JE TORTELLA, FC AF GENOVESE, RF MORETON, JE TORTELLA, FC TI EVALUATION OF NEUROPROTECTION AND BEHAVIORAL RECOVERY BY THE KAPPA-OPIOID, PD117302 FOLLOWING TRANSIENT FOREBRAIN ISCHEMIA SO BRAIN RESEARCH BULLETIN LA English DT Article DE ISCHEMIA; OPERANT BEHAVIOR; KAPPA OPIOID; RAT ID SCHEDULE-CONTROLLED BEHAVIOR; GLOBAL CEREBRAL-ISCHEMIA; RECEPTOR AGONIST; NEURONAL DAMAGE; HIPPOCAMPAL DAMAGE; UNANESTHETIZED RAT; MEMORY LOSS; DERIVATIVES; ANALGESICS; PROTECTION AB The effects of the selective kappa-opioid, PD117302 ((+/-)-trans-N-metyl-N-[2-(1-pyrrolidinyl) cyclohexyl] benzo [b]thiophene-4-acetamide), on transient (15 min) global forebrain ischemia, induced by four-vessel occlusion, was evaluated using a multiple fixed-ratio, fixed-interval schedule of food presentation in rats. The schedule produced distinctive patterns of responding in the fixed-ratio and fixed-interval components. Ischemia produced CA1 hippocampal necrosis and prolonged suppression of responding under both schedule components. When responding resumed, the pattern of responding rapidly returned. Response disruption and CA1 hippocampal necrosis were minimal or nonexistent in sham-occluded rats. Behavioral recovery time under both components of the schedule of reinforcement correlated with CA1 necrosis. On average, CA1 necrosis was less, and behavioral recovery time was shorter, in rats treated with PD117302 postocclusion as compared with vehicle-treated rats. The difference, however, did not reach statistical significance. These results demonstrate the utility of schedule-controlled responding for evaluating potentially therapeutic compounds for the treatment of ischemic injury. These results also further characterize the neuroprotective actions of kappa opioids. C1 UNIV MARYLAND,SCH PHARM,DEPT PHARMACOL & EXPTL THERAPEUT,BALTIMORE,MD 21201. RP GENOVESE, RF (reprint author), WALTER REED ARMY MED CTR,WALTER REED ARMY INST RES,DEPT MED NEUROSCI,WASHINGTON,DC 20307, USA. NR 42 TC 16 Z9 16 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0361-9230 J9 BRAIN RES BULL JI Brain Res. Bull. PY 1994 VL 34 IS 2 BP 111 EP 116 DI 10.1016/0361-9230(94)90006-X PG 6 WC Neurosciences SC Neurosciences & Neurology GA NH283 UT WOS:A1994NH28300006 PM 8044684 ER PT J AU KOESTER, SK MAENPAA, JU WIEBE, VJ BAKER, WJ WURZ, GT SEYMOUR, RC KOEHLER, RE DEGREGORIO, MW AF KOESTER, SK MAENPAA, JU WIEBE, VJ BAKER, WJ WURZ, GT SEYMOUR, RC KOEHLER, RE DEGREGORIO, MW TI FLOW-CYTOMETRY - POTENTIAL UTILITY IN MONITORING DRUG EFFECTS IN BREAST-CANCER SO BREAST CANCER RESEARCH AND TREATMENT LA English DT Article DE ANTIESTROGENS; BREAST CANCER; DRUG RESISTANCE; FLOW CYTOMETRY; TAMOXIFEN; TOREMIFENE ID MULTIDRUG RESISTANCE; TAMOXIFEN; CELLS; TOREMIFENE; TUMORS; ACCUMULATION; DOXORUBICIN; CARCINOMA; KINETICS; THERAPY AB Flow cytometric analysis of DNA ploidy and S-phase fraction are well recognized prognostic indicators in breast cancer. The present paper deals with the widening of the applications of flow cytometry to monitoring the effectiveness of antiestrogen therapy, detecting clonal selection and emergence of drug resistance, and monitoring chemosensitizing properties of drugs. Antiestrogen activity can be studied by DNA flow cytometry to address clinical research problems such as patient-specific pharmacokinetics, dosing compliance, and acquired antiestrogen resistance. Patient plasma specimens containing various concentrations of triphenylethylenes can be monitored for drug-induced effects using cell cycle measurements and correlated to in vivo drug levels. DNA flow cytometry has also been instrumental in the study of the effects of prolonged low-dose (0.5 mu M for > 100 days) tamoxifen treatment on human estrogen receptor negative MDA-MB-231 cells, where it was shown that tamoxifen may significantly alter cell cycle kinetics and tumorigenicity of these cells, selecting a new, more aggressive, and rapidly growing clone. Lastly, it has been shown that the chemosensitizing properties of another triphenylethylene antiestrogen, toremifene, on estrogen receptor negative, multidrug resistant MDA-MB-231-A1 human breast cancer cells can be studied using flow cytometric analysis. Toremifene (and its metabolites N-desmethyltoremifene and toremifene IV) are able to ''resensitize'' MDA-MB-231-A1 cells to vinblastine and doxorubicin, as reflected in a marked shift of cells to G(2)/M phase of the cell cycle. Flow cytometry is a widely available technique that might be applied clinically to monitor, at the cellular level, drug effects on tumors, including the modulators of drug resistance. C1 UNIV TEXAS,HLTH SCI CTR,DEPT MED MED ONCOL,CANC THERAPY & RES CTR,SAN ANTONIO,TX 78284. BROOKE ARMY MED CTR,SAN ANTONIO,TX. UNIV TURKU,TURKU,FINLAND. FU NCI NIH HHS [R01 CA-30251, P50 CA58183] NR 30 TC 9 Z9 9 U1 0 U2 0 PU KLUWER ACADEMIC PUBL PI DORDRECHT PA SPUIBOULEVARD 50, PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS SN 0167-6806 J9 BREAST CANCER RES TR JI Breast Cancer Res. Treat. PY 1994 VL 32 IS 1 BP 57 EP 65 DI 10.1007/BF00666206 PG 9 WC Oncology SC Oncology GA PL181 UT WOS:A1994PL18100007 PM 7819587 ER PT J AU EDSTEIN, MD SHANKS, GD TEJAISAVADHARM, P RIECKMANN, KH WEBSTER, HK AF EDSTEIN, MD SHANKS, GD TEJAISAVADHARM, P RIECKMANN, KH WEBSTER, HK TI OXIDATIVE ACTIVATION OF PROGUANIL AND DAPSONE ACETYLATION IN THAI SOLDIERS SO BRITISH JOURNAL OF CLINICAL PHARMACOLOGY LA English DT Note DE POLYMORPHISM; PROGUANIL; DAPSONE; MALARIA ID ACTIVE METABOLITE CYCLOGUANIL; INVITRO ANTIMALARIAL ACTIVITY; DOSE PHARMACOKINETICS; DRUG-METABOLISM; POLYMORPHISM; VARIABILITY AB The prevalence of putative poor metaboliser (PM) phenotypes of proguanil oxidation in Caucasian populations is 3-10%. The PM frequency in Oriental populations is unknown. In this study the plasma metabolic ratios of proguanil and dapsone to their principal metabolites cycloguanil and monoacetyldapsone were determined in Thai soldiers receiving antifolate drug combinations for malaria prophylaxis. The distribution ratio of proguanil to cycloguanil (PROG/CYC) was highly skewed with no evidence of bimodality. Assuming subjects with a PROG/CYC ratio greater than 10 are PMs from studies in Caucasians, the incidence of PMs in the soldiers would be 18% (30 of 170). The mean PROG/CYC ratio for PMs in the Thai soldiers was 31.2 +/- 28.9 (n = 30) compared with 25.5 +/- 2.5 (n = 3) in a study of Caucasians. The corresponding values for putative EMs were 5.4 +/- 2.1 (n = 140) and 2.4 +/- 0.2 (n = 134). Similar to other Oriental populations, Thais were found to be predominantly (76%, 173 of 228) rapid acetylators of dapsone. C1 ARMED FORCES RES INST MED SCI,BANGKOK 10400,THAILAND. RP EDSTEIN, MD (reprint author), ARMY MALARIA RES UNIT,LIVERPOOL MIL AREA,INGLEBURN,NSW 2174,AUSTRALIA. RI Shanks, George Dennis/F-4056-2014 OI Shanks, George Dennis/0000-0001-5763-8660 NR 18 TC 27 Z9 27 U1 1 U2 1 PU BLACKWELL SCIENCE LTD PI OXFORD PA OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL SN 0306-5251 J9 BRIT J CLIN PHARMACO JI Br. J. Clin. Pharmacol. PD JAN PY 1994 VL 37 IS 1 BP 67 EP 70 PG 4 WC Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA MR096 UT WOS:A1994MR09600012 PM 8148220 ER PT B AU LAROCCA, SA AF LAROCCA, SA BE Borchardt, FL Johnson, EMT TI A voice interactive multimedia (VIM) language laboratory in 1994 SO CALICO '94 ANNUAL SYMPOSIUM - PROCEEDINGS OF THE COMPUTER ASSISTED LANGUAGE INSTRUCTION CONSORTIUM ON HUMAN FACTORS LA English DT Proceedings Paper CT Computer-Assisted-Language-Instruction-Consortium 1994 Annual Symposium on Human Factors (CALICO 94) CY MAR 14-18, 1994 CL NORTHERN ARIZONA UNIV, FLAGSTAFF, AZ SP CALICO, NO Arizona Univ, Duke Univ HO NORTHERN ARIZONA UNIV C1 US MIL ACAD,DEPT FOREIGN LANGUAGES,W POINT,NY 10996. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CALICO PI DURHAM PA DUKE UNIVERSITY 014 LANGUAGE CENTER BOX 90267, DURHAM, NC 27708-0267 PY 1994 BP 145 EP 147 PG 3 WC Education & Educational Research; Ergonomics SC Education & Educational Research; Engineering GA BD78B UT WOS:A1994BD78B00025 ER PT B AU MOBLEY, SB AF MOBLEY, SB BE Watkins, WR Clement, D TI UNITED-ARMY MISSILE COMMAND DUAL-MODE MILLIMETER-WAVE INFRARED SIMULATOR DEVELOPMENT SO CHARACTERIZATION AND PROPAGATION OF SOURCES AND BACKGROUNDS SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Characterization and Propagation of Sources and Backgrounds CY APR 06-07, 1994 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,MISSILE COMMAND,SYST SIMULAT & DEV DIRECTORATE,REDSTONE ARSENAL,AL 35809. NR 0 TC 11 Z9 11 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1527-8 J9 P SOC PHOTO-OPT INS PY 1994 VL 2223 BP 100 EP 111 DI 10.1117/12.177947 PG 12 WC Engineering, Aerospace; Computer Science, Software Engineering; Optics SC Engineering; Computer Science; Optics GA BA83W UT WOS:A1994BA83W00009 ER PT B AU BUFORD, JA MOBLEY, SB AF BUFORD, JA MOBLEY, SB BE Watkins, WR Clement, D TI UNITED-STATES-ARMY MISSILE COMMAND HARDWARE-IN-THE-LOOP INFRARED PROJECTOR DEVELOPMENT SO CHARACTERIZATION AND PROPAGATION OF SOURCES AND BACKGROUNDS SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Characterization and Propagation of Sources and Backgrounds CY APR 06-07, 1994 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,MISSILE COMMAND,REDSTONE ARSENAL,AL 35898. NR 0 TC 2 Z9 2 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1527-8 J9 P SOC PHOTO-OPT INS PY 1994 VL 2223 BP 112 EP 123 PG 12 WC Engineering, Aerospace; Computer Science, Software Engineering; Optics SC Engineering; Computer Science; Optics GA BA83W UT WOS:A1994BA83W00010 ER PT B AU MCMANAMEY, JR WALKER, GW AF MCMANAMEY, JR WALKER, GW BE Watkins, WR Clement, D TI EFFECT OF A CAMERA ON APPARENT SCENE CORRELATION LENGTH SO CHARACTERIZATION AND PROPAGATION OF SOURCES AND BACKGROUNDS SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Characterization and Propagation of Sources and Backgrounds CY APR 06-07, 1994 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,BELVOIR RES DEV & ENGN CTR,FT BELVOIR,VA 22060. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1527-8 J9 P SOC PHOTO-OPT INS PY 1994 VL 2223 BP 149 EP 159 DI 10.1117/12.177909 PG 11 WC Engineering, Aerospace; Computer Science, Software Engineering; Optics SC Engineering; Computer Science; Optics GA BA83W UT WOS:A1994BA83W00013 ER PT B AU SMITH, RW CARROW, WW AF SMITH, RW CARROW, WW BE Watkins, WR Clement, D TI NEW MILLIMETER-WAVE TRANSMISSIOMETER SYSTEM SO CHARACTERIZATION AND PROPAGATION OF SOURCES AND BACKGROUNDS SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Characterization and Propagation of Sources and Backgrounds CY APR 06-07, 1994 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,TEST & EVALUAT COMMAND,FT BELVOIR METEOROL TEAM,FT BELVOIR,VA 22060. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1527-8 J9 P SOC PHOTO-OPT INS PY 1994 VL 2223 BP 187 EP 192 DI 10.1117/12.177912 PG 6 WC Engineering, Aerospace; Computer Science, Software Engineering; Optics SC Engineering; Computer Science; Optics GA BA83W UT WOS:A1994BA83W00016 ER PT B AU BILLINGSLEY, DR WATKINS, WR AF BILLINGSLEY, DR WATKINS, WR BE Watkins, WR Clement, D TI SYSTEM AND ENVIRONMENTAL-CONDITIONS THAT IMPACT AN IMAGING-SYSTEMS OTF SO CHARACTERIZATION AND PROPAGATION OF SOURCES AND BACKGROUNDS SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Characterization and Propagation of Sources and Backgrounds CY APR 06-07, 1994 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,BATTLEFIELD ENVIRONM DIRECTORATE,WHITE SANDS MISSILE RANGE,NM 88002. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1527-8 J9 P SOC PHOTO-OPT INS PY 1994 VL 2223 BP 379 EP 389 DI 10.1117/12.177946 PG 11 WC Engineering, Aerospace; Computer Science, Software Engineering; Optics SC Engineering; Computer Science; Optics GA BA83W UT WOS:A1994BA83W00033 ER PT B AU HOOCK, DW GIEVER, JC AF HOOCK, DW GIEVER, JC BE Watkins, WR Clement, D TI MODELING EFFECTS OF TERRAIN AND ILLUMINATION ON VISIBILITY AND THE VISUALIZATION OF HAZE AND AEROSOLS SO CHARACTERIZATION AND PROPAGATION OF SOURCES AND BACKGROUNDS SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Characterization and Propagation of Sources and Backgrounds CY APR 06-07, 1994 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,RES LAB,BATTLEFIELD ENVIRONM DIRECTORATE,WHITE SANDS MISSILE RANGE,NM 88002. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1527-8 J9 P SOC PHOTO-OPT INS PY 1994 VL 2223 BP 450 EP 461 PG 12 WC Engineering, Aerospace; Computer Science, Software Engineering; Optics SC Engineering; Computer Science; Optics GA BA83W UT WOS:A1994BA83W00039 ER PT B AU TOFSTED, DH AF TOFSTED, DH BE Watkins, WR Clement, D TI SPECTRAL ESTIMATION AND PROCESSING OF IMAGERY DATA SO CHARACTERIZATION AND PROPAGATION OF SOURCES AND BACKGROUNDS SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Characterization and Propagation of Sources and Backgrounds CY APR 06-07, 1994 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,RES LAB,WHITE SANDS MISSILE RANGE,NM 88002. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1527-8 J9 P SOC PHOTO-OPT INS PY 1994 VL 2223 BP 511 EP 520 DI 10.1117/12.177941 PG 10 WC Engineering, Aerospace; Computer Science, Software Engineering; Optics SC Engineering; Computer Science; Optics GA BA83W UT WOS:A1994BA83W00044 ER PT B AU LAWLER, W HARRISON, L LEVINE, PA SAUER, DJ HSEUH, FL SHALLCROSS, FV MEARY, GM TAYLOR, GC AF LAWLER, W HARRISON, L LEVINE, PA SAUER, DJ HSEUH, FL SHALLCROSS, FV MEARY, GM TAYLOR, GC BE Blouke, MM TI PERFORMANCE OF HIGH-FRAME-RATE, BACK-ILLUMINATED CCD IMAGERS SO CHARGE-COUPLED DEVICES AND SOLID STATE OPTICAL SENSORS IV SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Charge-Coupled Devices and Solid State Optical Sensors IV CY FEB 07-08, 1994 CL SAN JOSE, CA SP SOC IMAGING SCI & TECHNOL, SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,RES LAB,ADELPHI,MD 20783. NR 0 TC 3 Z9 3 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1467-0 J9 P SOC PHOTO-OPT INS PY 1994 VL 2172 BP 90 EP 99 DI 10.1117/12.172774 PG 10 WC Instruments & Instrumentation; Optics SC Instruments & Instrumentation; Optics GA BA43M UT WOS:A1994BA43M00009 ER PT B AU LAWLER, B HARRISON, L KIM, J WEN, D PINTER, J AF LAWLER, B HARRISON, L KIM, J WEN, D PINTER, J BE Blouke, MM TI HIGH-FRAME-RATE CCD IMAGER WITH NONLINEAR CHARGE SAMPLING SO CHARGE-COUPLED DEVICES AND SOLID STATE OPTICAL SENSORS IV SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Charge-Coupled Devices and Solid State Optical Sensors IV CY FEB 07-08, 1994 CL SAN JOSE, CA SP SOC IMAGING SCI & TECHNOL, SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,RES LAB,ADELPHI,MD 20783. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1467-0 J9 P SOC PHOTO-OPT INS PY 1994 VL 2172 BP 133 EP 142 PG 10 WC Instruments & Instrumentation; Optics SC Instruments & Instrumentation; Optics GA BA43M UT WOS:A1994BA43M00013 ER PT B AU MENKING, DE HEITZ, JM ANIS, NA THOMPSON, RG AF MENKING, DE HEITZ, JM ANIS, NA THOMPSON, RG BE Lieberman, RA TI ANTIBODY-BASED BACTERIAL TOXIN DETECTION SO CHEMICAL, BIOCHEMICAL, AND ENVIRONMENTAL FIBER SENSORS V SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Chemical, Biochemical, and Environmental Fiber Sensors V CY SEP 07-09, 1993 CL BOSTON, MA SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS, AUTOMATED IMAGING ASSOC, CARNEGIE MELLON UNIV, CTR EXCELLENCE OPT DATA PROC, UNIV CONNECTICUT, ADV TECHNOL CTR PRECIS MFG, INT SOC PHOTOGRAMMETRY & REMOTE SENSING C1 USA,CTR DEV & ENGN,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1333-X J9 P SOC PHOTO-OPT INS PY 1994 VL 2068 BP 145 EP 150 DI 10.1117/12.170668 PG 6 WC Instruments & Instrumentation; Optics SC Instruments & Instrumentation; Optics GA BA45J UT WOS:A1994BA45J00016 ER PT J AU IACONOCONNORS, LC NOVAK, J ROSSI, C MANGIAFICO, J KSIAZEK, T AF IACONOCONNORS, LC NOVAK, J ROSSI, C MANGIAFICO, J KSIAZEK, T TI ENZYME-LINKED-IMMUNOSORBENT-ASSAY USING A RECOMBINANT BACULOVIRUS-EXPRESSED BACILLUS-ANTHRACIS PROTECTIVE ANTIGEN (PA) - MEASUREMENT OF HUMAN ANTI-PA ANTIBODIES SO CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY LA English DT Article ID MONOCLONAL-ANTIBODIES; TOXIN; COMPONENT; VACCINE; VIRUS AB We developed an antigen capture enzyme-linked immunosorbent assay (ELISA) which does not require purified protective antigen (PA) for detection of human antibodies to Bacillus anthracis PA. Lysates of Spodoptera frugiperda (Sf-9) cells infected with recombinant baculovirus containing the PA gene were used as the source of PA to develop the ELISA. Recombinant PA from crude Sf-9 cell lysates or PA. purified from B. anthracis Sterne strain was captured by an anti-PA monoclonal antibody coated onto microtiter plates. We demonstrated that human serum antibody titers to PA were identical in the ELISA whether we used crude Sf-9 cell lysates containing recombinant baculovirus-expressed PA or purified Sterne PA. Finally, false-positive results observed in a direct ELISA were eliminated with this antigen capture ELISA. Thus, the antigen capture ELISA with crude preparations of baculovirus-expressed PA is reliable, safe, and inexpensive for determining anti-PA antibody levels in human sera. C1 USA,MED RES INST INFECT DIS,DIV VIROL,FREDERICK,MD 21702. USA,MED RES INST INFECT DIS,DIV BACTERIOL,FREDERICK,MD 21702. USA,MED RES INST INFECT DIS,DIV APPL RES,FREDERICK,MD 21702. NR 17 TC 22 Z9 22 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 1071-412X J9 CLIN DIAGN LAB IMMUN JI Clin. Diagn. Lab. Immunol. PD JAN PY 1994 VL 1 IS 1 BP 78 EP 82 PG 5 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA PT561 UT WOS:A1994PT56100015 PM 7496927 ER PT J AU SFIKAKIS, PP CHARALAMBOPOULOS, D VAYIOPOULOS, G OGLESBY, R SFIKAKIS, P TSOKOS, GC AF SFIKAKIS, PP CHARALAMBOPOULOS, D VAYIOPOULOS, G OGLESBY, R SFIKAKIS, P TSOKOS, GC TI INCREASED LEVELS OF INTERCELLULAR-ADHESION MOLECULE-1 IN THE SERUM OF PATIENTS WITH SYSTEMIC LUPUS-ERYTHEMATOSUS SO CLINICAL AND EXPERIMENTAL RHEUMATOLOGY LA English DT Article DE CELL ADHESION; SOLUBLE ICAM-1; SOLUBLE IL-2R; SLE ID SOLUBLE INTERLEUKIN-2 RECEPTOR; DISEASE-ACTIVITY; IMMUNE-SYSTEM; EXPRESSION; ICAM-1; CELLS; FORM AB Intercellular adhesion molecule-1 (ICAM-1) is a membrane-bound molecule that is primarily involved in cell-cell adhesive interactions of the immune system. The levels of soluble ICAM-1 (s-ICAM-1) shed into the circulation were studied in the sera of patients with systemic lupus erythematosus (SLE) by an enzyme linked immunosorbent assay. Serum concentrations of s-ICAM-1 were significantly increased in 61 patients with SLE compared to 51 controls (mean +/- SEM: 564 +/- 30 versus 348 +/- 17 ng/ml, p < 0.0001) and 41% of patients had higher serum levels than the normal cut off value of 584 ng/ml. Among the various clinical manifestations, skirt involvement was significantly associated with high serum levels of s-ICAM-1. Individual values of serum s-ICAM-1 concentrations in patients with SLE correlated significantly with two different disease activity indices, as well as with the erythrocyte sedimentation rate and serum levels of soluble interleukin-2 receptors, but not with serum levels of anti-dsDNA antibodies or C4. No significant differences in s-ICAM-1 levels were found between patients receiving immunomodulatory treatment and those who were not These findings suggest that s-ICAM-1 measurement may serve as an additional serologic marker of disease activity in patients with SLE. Further studies so determine whether increased s-ICAM-1 shedding has any pathogenetic significance or biological role in SLE are warranted. C1 WALTER REED ARMY MED CTR,RHEUMATOL & CLIN IMMUNOL SERV,WASHINGTON,DC. UNIFORMED SERV UNIV HLTH SCI,DEPT MED,BETHESDA,MD 20814. LAIKON GEN HOSP,DEPT PROPAEDEUT MED 1,ATHENS,GREECE. NR 30 TC 38 Z9 40 U1 0 U2 0 PU CLINICAL & EXPER RHEUMATOLOGY PI PISA PA VIA SANTA MARIA 31, 56126 PISA, ITALY SN 0392-856X J9 CLIN EXP RHEUMATOL JI Clin. Exp. Rheumatol. PD JAN-FEB PY 1994 VL 12 IS 1 BP 5 EP 9 PG 5 WC Rheumatology SC Rheumatology GA MV468 UT WOS:A1994MV46800002 PM 7909280 ER PT J AU GASSER, RA MAGILL, AJ OSTER, CN FRANKE, ED GROGL, M BERMAN, JD AF GASSER, RA MAGILL, AJ OSTER, CN FRANKE, ED GROGL, M BERMAN, JD TI PANCREATITIS INDUCED BY PENTAVALENT ANTIMONIAL AGENTS DURING TREATMENT OF LEISHMANIASIS SO CLINICAL INFECTIOUS DISEASES LA English DT Article ID AMERICAN CUTANEOUS LEISHMANIASIS; SODIUM STIBOGLUCONATE PENTOSTAM; VISCERAL LEISHMANIASIS; MUCOSAL LEISHMANIASIS; EFFICACY; KETOCONAZOLE AB Pentavalent antimony (Sb-v). formulated as sodium stibogluconate or meglumine antimoniate, is the standard treatment for the leishmaniases. In 16 of 17 consecutive, prospectively observed patients in Washington D.C., serum levels of amylase and lipase rose to abnormal values after therapy with sodium stibogluconate was started; 12 of 17 had symptoms of pancreatitis. Sb-v therapy was continued to completion in 7 of 17 patients and interrupted in 10 of 17. Pancreatitis improved in every patient after Sb-v therapy was stopped. Sb-v treatment was resumed after brief interruptions in 6 of 10 patients. All six of these patients had flares of pancreatitis, but each completed therapy. Subsequently, we measured amylase and lipase levels in stored sera from 32 patients treated in Peru with either sodium stibogluconlate or meglumine antimoniate for mucosal leishmaniasis. In all 32 Peruvian patients, serum amylase and lipase rose to abnormal levels during Sb-v therapy; 11 of 32 had symptoms of pancreatitis. Standard Sb-v regimens induce pancreatitis in almost all patients, but continued therapy is often tolerated; pancreatitis subsides when therapy is stopped, and rechallenge may be tolerated after a brief halt in treatment. C1 WALTER REED ARMY INST RES, DIV EXPTL THERAPEUT, WASHINGTON, DC 20307 USA. WALTER REED ARMY MED CTR, INFECT DIS SERV, WASHINGTON, DC USA. WALTER REED ARMY INST RES, DEPT IMMUNOL, WASHINGTON, DC USA. USN, MED RES INST DETACHMENT, LIMA, PERU. RI Villasante, Eileen/G-3602-2011 NR 39 TC 96 Z9 103 U1 0 U2 5 PU OXFORD UNIV PRESS INC PI CARY PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA SN 1058-4838 EI 1537-6591 J9 CLIN INFECT DIS JI Clin. Infect. Dis. PD JAN PY 1994 VL 18 IS 1 BP 83 EP 90 PG 8 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA MX205 UT WOS:A1994MX20500009 PM 7519887 ER PT J AU BURANS, JP SHARP, T WALLACE, I LONGER, C THORNTON, S BATCHELOR, R CLEMENS, V HYAMS, KC AF BURANS, JP SHARP, T WALLACE, I LONGER, C THORNTON, S BATCHELOR, R CLEMENS, V HYAMS, KC TI THREAT OF HEPATITIS-E VIRUS-INFECTION IN SOMALIA DURING OPERATION RESTORE HOPE SO CLINICAL INFECTIOUS DISEASES LA English DT Note ID NON-B HEPATITIS; NON-A; CHILDREN; EPIDEMIC; ASSAY AB In support of Operation Restore Hope, the United States military established a diagnostic laboratory for infectious diseases, the Joint Forward Laboratory, in Mogadishu, Somalia. Because sporadic hepatitis due to unknown causes was a frequent problem, staff members of the Joint Forward Laboratory evaluated 31 Somalis, five displaced Ethiopians, and three Western relief workers who had acute clinical hepatitis. Patients lived in multiple locations in Somalia-Mogadishu, Baidoa, and Merca-and became ill between December 1992 and February 1993. IgM antibody to hepatitis A virus was found in one English relief worker, and IgM I antibody to hepatitis E virus was found in 20 (65%) of 31 Somalis, two (40%) of five Ethiopians, and two (67%) of three Western relief workers. No patient had evidence of acute hepatitis B, malaria, yellow fever, or other arbovirus infections. These data indicate that hepatitis E virus-the major cause of enterically transmitted non-A, non-B hepatitis-was a common cause of acute sporadic hepatitis in Somalia during the initial stages of Operation Restore Hope. C1 USN,MED CTR,SAN DIEGO,CA. WALTER REED ARMY INST RES,WASHINGTON,DC. USN,MED RES UNIT 3,CAIRO,EGYPT. MSF,MISSION SOMALIE,PARIS,FRANCE. RP BURANS, JP (reprint author), USN,MED RES INST,CODE 412,8901 WISCONSIN AVE,BETHESDA,MD 20889, USA. NR 12 TC 16 Z9 17 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 1058-4838 J9 CLIN INFECT DIS JI Clin. Infect. Dis. PD JAN PY 1994 VL 18 IS 1 BP 100 EP 102 PG 3 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA MX205 UT WOS:A1994MX20500013 PM 8054416 ER PT B AU SMITH, JM AF SMITH, JM BE Arcilla, AS Stive, MJF Kraus, NC TI Undertow at SUPERTANK SO COASTAL DYNAMICS '94 - PROCEEDINGS OF AN INTERNATIONAL CONFERENCE ON THE ROLE OF THE LARGE SCALE EXPERIMENTS IN COASTAL RESEARCH LA English DT Proceedings Paper CT International Conference on the Role of the Large Scale Experiments in Coastal Research - Coastal Dynamics 94 CY FEB 21-25, 1994 CL UNIV POLITECN CATALUNYA, BARCELONA, SPAIN SP Minist Educ & Ciencia, Spain, USN, Off Naval Res, Ocean Engn Div, Commiss European Communities, DGXII, Generalitat Catalunya, Univ Politecn Catalunya, Amer Soc Civil Engineers, Japan Soc Civil Engineers, E T S Enginyers Camins, Canals & Ports Barcelona, UPC, Lab Enginyeria Maritima, UPC HO UNIV POLITECN CATALUNYA C1 USA,WATERWAYS EXPT STN,COASTAL ENGN RES CTR,VICKSBURG,MS 39180. NR 0 TC 1 Z9 1 U1 0 U2 1 PU AMER SOC CIVIL ENGINEERS PI NEW YORK PA UNITED ENGINEERING CENTER, 345 E 47TH ST, NEW YORK, NY 10017-2398 BN 0-7844-0043-1 PY 1994 BP 220 EP 232 PG 3 WC Engineering, Marine; Engineering, Civil; Oceanography SC Engineering; Oceanography GA BD74N UT WOS:A1994BD74N00016 ER PT B AU MELBY, JA ASCE, AM TURK, GF AF MELBY, JA ASCE, AM TURK, GF BE Arcilla, AS Stive, MJF Kraus, NC TI Scale and modeling effects in concrete armor experiments SO COASTAL DYNAMICS '94 - PROCEEDINGS OF AN INTERNATIONAL CONFERENCE ON THE ROLE OF THE LARGE SCALE EXPERIMENTS IN COASTAL RESEARCH LA English DT Proceedings Paper CT International Conference on the Role of the Large Scale Experiments in Coastal Research - Coastal Dynamics 94 CY FEB 21-25, 1994 CL UNIV POLITECN CATALUNYA, BARCELONA, SPAIN SP Minist Educ & Ciencia, Spain, USN, Off Naval Res, Ocean Engn Div, Commiss European Communities, DGXII, Generalitat Catalunya, Univ Politecn Catalunya, Amer Soc Civil Engineers, Japan Soc Civil Engineers, E T S Enginyers Camins, Canals & Ports Barcelona, UPC, Lab Enginyeria Maritima, UPC HO UNIV POLITECN CATALUNYA C1 USA,WATERWAYS EXPT STN,COASTAL ENGN RES CTR,VICKSBURG,MS 39180. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC CIVIL ENGINEERS PI NEW YORK PA UNITED ENGINEERING CENTER, 345 E 47TH ST, NEW YORK, NY 10017-2398 BN 0-7844-0043-1 PY 1994 BP 686 EP 700 PG 3 WC Engineering, Marine; Engineering, Civil; Oceanography SC Engineering; Oceanography GA BD74N UT WOS:A1994BD74N00049 ER PT B AU PARCHURE, TM MCANALLY, WH NAIL, G AF PARCHURE, TM MCANALLY, WH NAIL, G BE Arcilla, AS Stive, MJF Kraus, NC TI Objectives of proposed large scale experimental facility (ESTEX) SO COASTAL DYNAMICS '94 - PROCEEDINGS OF AN INTERNATIONAL CONFERENCE ON THE ROLE OF THE LARGE SCALE EXPERIMENTS IN COASTAL RESEARCH LA English DT Proceedings Paper CT International Conference on the Role of the Large Scale Experiments in Coastal Research - Coastal Dynamics 94 CY FEB 21-25, 1994 CL UNIV POLITECN CATALUNYA, BARCELONA, SPAIN SP Minist Educ & Ciencia, Spain, USN, Off Naval Res, Ocean Engn Div, Commiss European Communities, DGXII, Generalitat Catalunya, Univ Politecn Catalunya, Amer Soc Civil Engineers, Japan Soc Civil Engineers, E T S Enginyers Camins, Canals & Ports Barcelona, UPC, Lab Enginyeria Maritima, UPC HO UNIV POLITECN CATALUNYA C1 USA,ENGINEER WATERWAYS EXPT STN,VICKSBURG,MS 39180. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC CIVIL ENGINEERS PI NEW YORK PA UNITED ENGINEERING CENTER, 345 E 47TH ST, NEW YORK, NY 10017-2398 BN 0-7844-0043-1 PY 1994 BP 809 EP 814 PG 4 WC Engineering, Marine; Engineering, Civil; Oceanography SC Engineering; Oceanography GA BD74N UT WOS:A1994BD74N00058 ER PT B AU BIRKEMEIER, WA THORNTON, EB AF BIRKEMEIER, WA THORNTON, EB BE Arcilla, AS Stive, MJF Kraus, NC TI The DUCK94 nearshore field experiment SO COASTAL DYNAMICS '94 - PROCEEDINGS OF AN INTERNATIONAL CONFERENCE ON THE ROLE OF THE LARGE SCALE EXPERIMENTS IN COASTAL RESEARCH LA English DT Proceedings Paper CT International Conference on the Role of the Large Scale Experiments in Coastal Research - Coastal Dynamics 94 CY FEB 21-25, 1994 CL UNIV POLITECN CATALUNYA, BARCELONA, SPAIN SP Minist Educ & Ciencia, Spain, USN, Off Naval Res, Ocean Engn Div, Commiss European Communities, DGXII, Generalitat Catalunya, Univ Politecn Catalunya, Amer Soc Civil Engineers, Japan Soc Civil Engineers, E T S Enginyers Camins, Canals & Ports Barcelona, UPC, Lab Enginyeria Maritima, UPC HO UNIV POLITECN CATALUNYA C1 USA,COASTAL ENGN RES CTR,ENGINEER WATERWAYS EXPT STN,VICKSBURG,MS 39180. NR 0 TC 2 Z9 2 U1 0 U2 0 PU AMER SOC CIVIL ENGINEERS PI NEW YORK PA UNITED ENGINEERING CENTER, 345 E 47TH ST, NEW YORK, NY 10017-2398 BN 0-7844-0043-1 PY 1994 BP 815 EP 821 PG 3 WC Engineering, Marine; Engineering, Civil; Oceanography SC Engineering; Oceanography GA BD74N UT WOS:A1994BD74N00059 ER EF