FN Thomson Reuters Web of Science™ VR 1.0 PT J AU Hakre, S Oyler, RJ Ferrell, KA Li, F Michael, NL Scott, PT Petruccelli, BP AF Hakre, Shilpa Oyler, Robert J. Ferrell, Kenneth A. Li, Fang Michael, Nelson L. Scott, Paul T. Petruccelli, Bruno P. TI Chlamydia trachomatis infection rates among a cohort of mobile soldiers stationed at Fort Bragg, North Carolina, 2005-2010 SO BMC PUBLIC HEALTH LA English DT Article DE Chlamydia; Army; Mobility ID SEXUALLY-TRANSMITTED-DISEASES; UNITED-STATES; GONORRHEA; PREVALENCE; SURVEILLANCE; INSTALLATION; SYSTEM; MEN AB Background: Fort Bragg, a large Army installation with reported high Chlamydia trachomatis (Ct) infection rates, is characterized by a highly mobile population and a surrounding Ct-endemic community. We assessed the rates of Ct incidence and recurrence among the installation's active component Army personnel and determined the association of soldier transience, sociodemographic factors, and history of sexually transmitted infection (STI) with these rates. Methods: A cohort of soldiers stationed at Fort Bragg during 2005 to mid-2010 was followed for incident and recurrent Ct infection using laboratory-confirmed reportable disease data. Linkage to demographic and administrative data permitted multivariate analysis to determine association of covariates with initial or recurrent infection. Results: Among 67,425 soldiers, 2,198 (3.3%) contracted an incident Ct infection (crude incidence, 21.7 per 1,000 person-years). Among soldiers followed for incident infection, 223 (10.6%, crude incidence 110.8 per 1,000 person-years) contracted a recurrent Ct infection. Being female, of lower rank, under 26 years of age, of non-white race, single, or with a high school diploma or less was significantly associated with incident Ct infection. Having breaks in duty or having deployments during follow-up was associated with a lower infection rate. Among women, having prior deployments was associated with a lower rate of both incident and recurrent infection. Specifically associated with recurrent infection in women was age under 21 years or no education beyond high school. Conclusions: This analysis reaffirms risk factors for Ct infection determined in other studies. In addition, infection risk was lower for more mobile soldiers and tied to the specific location of their regular duty assignment. The findings support the STI prevention efforts at Fort Bragg and the surrounding community, regardless of how often or for how long soldiers have deployed for military operations. C1 [Hakre, Shilpa; Li, Fang; Petruccelli, Bruno P.] Henry M Jackson Fdn Adv Mil Med, US Mil HIV Res Program, Bethesda, MD 20817 USA. [Oyler, Robert J.; Ferrell, Kenneth A.] Womack Army Med Ctr, Ft Bragg, NC USA. [Michael, Nelson L.; Scott, Paul T.] Walter Reed Army Inst Res, US Mil HIV Res Program, Bethesda, MD USA. RP Hakre, S (reprint author), Henry M Jackson Fdn Adv Mil Med, US Mil HIV Res Program, Bethesda, MD 20817 USA. EM shakre@hivresearch.org FU AFHSC FX We thank Dr. Angelia A. Eick-Cost for designing acquisition of, and facilitating, data extraction from the DMSS. We are grateful to staff at AFHSC for supporting the data extractions for this study. NR 30 TC 1 Z9 1 U1 0 U2 6 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1471-2458 J9 BMC PUBLIC HEALTH JI BMC Public Health PD FEB 20 PY 2014 VL 14 AR 181 DI 10.1186/1471-2458-14-181 PG 12 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA AC7QI UT WOS:000332725400001 PM 24552420 ER PT J AU Iida, J Clancy, R Dorchak, J Somiari, RI Somiari, S Cutler, ML Mural, RJ Shriver, CD AF Iida, Joji Clancy, Rebecca Dorchak, Jesse Somiari, Richard I. Somiari, Stella Cutler, Mary Lou Mural, Richard J. Shriver, Craig D. TI DNA Aptamers against Exon v10 of CD44 Inhibit Breast Cancer Cell Migration SO PLOS ONE LA English DT Article ID MUC1 TUMOR-MARKER; MOLECULAR MARKERS; EPH RECEPTORS; RNA APTAMERS; IDENTIFICATION; PROTEIN; SELECTION; MELANOMA; ISOFORMS; LIGANDS AB CD44 adhesion molecules are expressed in many breast cancer cells and have been demonstrated to play a key role in regulating malignant phenotypes such as growth, migration, and invasion. CD44 is an integral transmembrane protein encoded by a single 20-exon gene. The diversity of the biological functions of CD44 is the result of the various splicing variants of these exons. Previous studies suggest that exon v10 of CD44 plays a key role in promoting cancer invasion and metastasis, however, the molecular mechanisms are not clear. Given the fact that exon v10 is in the ectodomain of CD44, we hypothesized that CD44 forms a molecular complex with other cell surface molecules through exon v10 in order to promote migration of breast cancer cells. In order to test this hypothesis, we selected DNA aptamers that specifically bound to CD44 exon v10 using Systematic Evolution of Ligands by Exponential Enrichment (SELEX). We selected aptamers that inhibited migration of breast cancer cells. Co-immunoprecipitation studies demonstrated that EphA2 was co-precipitated with CD44. Pull-down studies demonstrated that recombinant CD44 exon v10 bound to EphA2 and more importantly aptamers that inhibited migration also prevented the binding of EphA2 to exon v10. These results suggest that CD44 forms a molecular complex with EphA2 on the breast cancer cell surface and this complex plays a key role in enhancing breast cancer migration. These results provide insight not only for characterizing mechanisms of breast cancer migration but also for developing target-specific therapy for breast cancers and possibly other cancer types expressing CD44 exon v10. C1 [Iida, Joji; Clancy, Rebecca; Dorchak, Jesse; Somiari, Stella] Windber Res Inst, Dept Cell Biol, Windber, PA 15963 USA. [Somiari, Richard I.] ITSI Biosci, Johnstown, PA USA. [Cutler, Mary Lou] Uniformed Serv Univ Hlth Sci, Dept Pathol, Bethesda, MD 20814 USA. [Mural, Richard J.] Windber Res Inst, Windber, PA USA. [Shriver, Craig D.] Walter Reed Army Med Ctr, Dept Surg, Bethesda, MD USA. RP Iida, J (reprint author), Windber Res Inst, Dept Cell Biol, Windber, PA 15963 USA. EM g.iida@wriwindber.org FU United States Department of Defense (Military Molecular Medicine Initiative) [MDA W81XWHH-05-20075, Protocol 01-20006]; USMCI [MDA-905-02-2-0005] FX This research was supported by a grant from the United States Department of Defense (Military Molecular Medicine Initiative MDA W81XWHH-05-20075, Protocol 01-20006) and USMCI (MDA-905-02-2-0005). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The opinion and assertions contained herein are the private views of the authors and are not to be construed as official or as representing the views of the Department of the Army or the Department of Defense. NR 47 TC 8 Z9 8 U1 2 U2 16 PU PUBLIC LIBRARY SCIENCE PI SAN FRANCISCO PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA SN 1932-6203 J9 PLOS ONE JI PLoS One PD FEB 19 PY 2014 VL 9 IS 2 AR e88712 DI 10.1371/journal.pone.0088712 PG 9 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA AB3TA UT WOS:000331711900041 PM 24586375 ER PT J AU de Ceglia, D Vincenti, MA Campione, S Capolino, F Haus, JW Scalora, M AF de Ceglia, Domenico Vincenti, Maria Antonietta Campione, Salvatore Capolino, Filippo Haus, Joseph W. Scalora, Michael TI Second-harmonic double-resonance cones in dispersive hyperbolic metamaterials SO PHYSICAL REVIEW B LA English DT Article ID LIGHT WAVES; NEAR-FIELD; RADIATION; HYPERLENS; PATTERN; MEDIA AB We study the formation of second-harmonic double-resonance cones in hyperbolic metamaterials. An electric dipole on the surface of the structure induces second-harmonic light to propagate into two distinct volume plasmon-polariton channels: a signal that propagates within its own peculiar resonance cone and a phase-locked signal that is trapped under the pump's resonance cone. Metamaterial dispersion and birefringence induce a large angular divergence between the two volume plasmon polaritons, making these structures suitable for subwavelength second- and higher-harmonic imaging microscopy. C1 [de Ceglia, Domenico; Vincenti, Maria Antonietta; Haus, Joseph W.] Natl Res Council AMRDEC, Charles M Bowden Res Lab, Redstone Arsenal, AL 35898 USA. [Campione, Salvatore; Capolino, Filippo] Univ Calif Irvine, Dept Elect Engn & Comp Sci, Irvine, CA 92697 USA. [Haus, Joseph W.] Univ Dayton, Electroopt Program, Dayton, OH 45469 USA. [Scalora, Michael] US Army RDECOM, Charles M Bowden Res Lab, AMRDEC, Redstone Arsenal, AL 35898 USA. RP de Ceglia, D (reprint author), Natl Res Council AMRDEC, Charles M Bowden Res Lab, Redstone Arsenal, AL 35898 USA. EM domenico.deceglia@us.army.mil RI Campione, Salvatore/A-2349-2015 OI Campione, Salvatore/0000-0003-4655-5485 FU National Research Council Research Associateship awards at the U.S. Army Aviation and Missile Research Development and Engineering Center FX This research was performed while authors D. de Ceglia, M. A. Vincenti, and J. W. Haus held National Research Council Research Associateship awards at the U.S. Army Aviation and Missile Research Development and Engineering Center. NR 43 TC 16 Z9 16 U1 4 U2 27 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1098-0121 EI 1550-235X J9 PHYS REV B JI Phys. Rev. B PD FEB 19 PY 2014 VL 89 IS 7 AR 075123 DI 10.1103/PhysRevB.89.075123 PG 7 WC Physics, Condensed Matter SC Physics GA AC3EH UT WOS:000332397300003 ER PT J AU Berninger, JP Martinovic-Weigelt, D Garcia-Reyero, N Escalon, L Perkins, EJ Ankley, GT Villeneuve, DL AF Berninger, Jason P. Martinovic-Weigelt, Dalma Garcia-Reyero, Natalia Escalon, Lynn Perkins, Edward J. Ankley, Gerald T. Villeneuve, Daniel L. TI Using Transcriptomic Tools to Evaluate Biological Effects Across Effluent Gradients at a Diverse Set of Study Sites in Minnesota, USA SO ENVIRONMENTAL SCIENCE & TECHNOLOGY LA English DT Article ID LARGE GENE LISTS; RISK-ASSESSMENT; BISPHENOL-A; IMPACTS; ECOTOXICOLOGY; EXPRESSION; SYSTEM; MODEL; FISH AB The aim of this study was to explore the utility of "omics" approaches in monitoring aquatic environments where complex, often unknown stressors make chemical-specific risk assessment untenable. We examined changes in the fathead minnow (Pimephales promelas) ovarian transcriptome following 4-day exposures conducted at three sites in Minnesota (MN, USA). Within each site, fish were exposed to water from three locations along a spatial gradient relative to a wastewater treatment plant (WWTP) discharge. After exposure, site-specific impacts on gene expression in ovaries were assessed. Using an intragradient point of comparison, biological responses specifically associated with the WWTP effluent were identified using functional enrichment analyses. Fish exposed to water from locations downstream of the effluent discharges exhibited many transcriptomic responses in common with those exposed to the effluent, indicating that effects of the discharge do not fully dissipate downstream. Functional analyses showed a range of biological pathways impacted through effluent exposure at all three sites. Several of those impacted pathways at each site could be linked to potential adverse reproductive outcomes associated with the hypothalamic pituitary gonadal (HPG) axis in female fathead minnows, specifically signaling pathways associated with oocyte meiosis, TGF-beta signaling, gonadotropin-releasing hormone (GnRH) and epidermal growth factor receptor family (ErbB), and gene sets associated with cyclin B-1 and metalloproteinase. The utility of this approach comes from the ability to identify biological responses to pollutant exposure, particularly those that can be tied to adverse outcomes at the population level and those that identify molecular targets for future studies. C1 [Berninger, Jason P.] US EPA, Natl Res Council, Duluth, MN 55804 USA. [Martinovic-Weigelt, Dalma] Univ St Thomas, St Paul, MN 55105 USA. [Garcia-Reyero, Natalia] Mississippi State Univ, Inst Genom Biocomp & Biotechnol, Starkville, MS 39762 USA. [Escalon, Lynn; Perkins, Edward J.] US Army Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. [Ankley, Gerald T.; Villeneuve, Daniel L.] US EPA, Midcontinent Ecol Div, Duluth, MN 55804 USA. RP Berninger, JP (reprint author), US EPA, Natl Res Council, 6201 Congdon Blvd, Duluth, MN 55804 USA. EM Berninger.Jason@epa.gov RI Berninger, Jason/O-2401-2016; OI Berninger, Jason/0000-0003-3045-7899; Martinovic-Weigelt, Dalma/0000-0002-9973-4965 FU US Army Environmental Quality Research Program [BAA 11-4838] FX The views expressed in this paper are those of the authors and do not necessarily reflect the views or policies of the US Environmental Protection Agency. This work was partly funded by the US Army Environmental Quality Research Program (including BAA 11-4838). Permission for publishing this information has been granted by the Chief of Engineers. The authors thank Kathy Lee (USGS), Heiko Schoenfuss (St. Cloud State University), Leah Wehmas, and their co-workers for their efforts in collecting samples that were used in this study and Anthony Schroeder for helpful comments on the manuscript. NR 29 TC 12 Z9 12 U1 3 U2 36 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0013-936X EI 1520-5851 J9 ENVIRON SCI TECHNOL JI Environ. Sci. Technol. PD FEB 18 PY 2014 VL 48 IS 4 BP 2404 EP 2412 DI 10.1021/es4040254 PG 9 WC Engineering, Environmental; Environmental Sciences SC Engineering; Environmental Sciences & Ecology GA AB4QD UT WOS:000331774100038 PM 24433150 ER PT J AU Kumar, P Malinovskaya, SA Sola, IR Malinovsky, VS AF Kumar, Praveen Malinovskaya, Svetlana A. Sola, Ignacio R. Malinovsky, Vladimir S. TI Selective creation of maximum coherence in multi-level A system SO MOLECULAR PHYSICS LA English DT Article DE optimal control theory; coherent population transfer; Raman coherence; pulse train ID POPULATION TRANSFER; QUANTUM AB We consider the creation of the maximum Raman coherence in the six-level system using optimal control theory. Optimal fields are designed for different initial conditions, resonant, and off-resonant, using the Krotov method including a reference field into the cost functional. Suppression of the population transfer to the intermediate level is achieved via an additional functional constraint which depends on the system dynamics. We demonstrate that the spectrum of the optimised fields has major contribution from the corresponding resonant frequencies independently of the choice of carrier frequency of the initial guess field. We also indicate that the pulse train emerges as a solution of the control problem of coherence optimisation in multi-level quantum systems. C1 [Kumar, Praveen; Malinovskaya, Svetlana A.; Malinovsky, Vladimir S.] Stevens Inst Technol, Dept Phys, Hoboken, NJ 07030 USA. [Kumar, Praveen] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX 79409 USA. [Sola, Ignacio R.] Univ Complutense, Dept Quim Fis 1, E-28040 Madrid, Spain. [Malinovsky, Vladimir S.] Army Res Lab, Adelphi, MD USA. RP Malinovsky, VS (reprint author), Stevens Inst Technol, Dept Phys, Hoboken, NJ 07030 USA. EM vsmalinovsky@gmail.com FU National Science Foundation [NSF PHY11-25915, PHY12-05454] FX This research was supported in part by the National Science Foundation under Grant No. NSF PHY11-25915 and PHY12-05454. NR 17 TC 1 Z9 1 U1 1 U2 8 PU TAYLOR & FRANCIS LTD PI ABINGDON PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND SN 0026-8976 EI 1362-3028 J9 MOL PHYS JI Mol. Phys. PD FEB 16 PY 2014 VL 112 IS 3-4 SI SI BP 326 EP 331 DI 10.1080/00268976.2013.809166 PG 6 WC Chemistry, Physical; Physics, Atomic, Molecular & Chemical SC Chemistry; Physics GA 304OL UT WOS:000330756100002 ER PT J AU DeLacy, BG Lacey, S Zhang, DJ Valdes, E Hoang, K AF DeLacy, Brendan G. Lacey, Steven Zhang, Dajie Valdes, Erica Hoang, Kenneth TI Controlling the morphology of indium tin oxide using PEG-assisted hydrothermal synthesis SO MATERIALS LETTERS LA English DT Article DE Tin-doped indium oxide; ITO; Nanomaterials; Semiconductor ID OPTICAL-PROPERTIES; NANORODS; FILMS; NANOCRYSTALS AB We report the synthesis of indium tin oxide (ITO) powders with varying morphologies using hydrothermal synthesis. Polyethylene glycol (PEG) 400 and sodium hydroxide (NaOH) were used to promote the formation of non-spherical morphologies. The ratio of PEG to NaOH was found to influence the morphology of the products. Nanocrystalline spheres, cubes, block-like structures, rods, and dendrites were produced in the study. All resultant products were characterized by X-ray powder diffraction, scanning electron microscopy, and scanning transmission electron microscopy. Influential factors on the growth mechanisms of lTO are discussed. Published by Elsevier B.V. C1 [DeLacy, Brendan G.; Lacey, Steven; Valdes, Erica; Hoang, Kenneth] US Army Edgewood Chem Biol Ctr, Res & Technol Directorate, Aberdeen Proving Ground, MD 21010 USA. [Zhang, Dajie] Johns Hopkins Univ, Adv Technol Lab, Baltimore, MD USA. RP DeLacy, BG (reprint author), US Army Edgewood Chem Biol Ctr, Res & Technol Directorate, 5183 Blackhawk Rd, Aberdeen Proving Ground, MD 21010 USA. EM brendan.g.delacy.civ@mail.mil FU U.S. Army Edgewood Chemical Biological Center Research & Technology Directorate FX The authors would like to thank the U.S. Army Edgewood Chemical Biological Center Research & Technology Directorate for financial support. NR 17 TC 3 Z9 3 U1 1 U2 20 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0167-577X EI 1873-4979 J9 MATER LETT JI Mater. Lett. PD FEB 15 PY 2014 VL 117 BP 108 EP 111 DI 10.1016/j.matlet.2013.11.114 PG 4 WC Materials Science, Multidisciplinary; Physics, Applied SC Materials Science; Physics GA AN8FD UT WOS:000340837800030 ER PT J AU Nagaraja, S Wallqvist, A Reifman, J Mitrophanov, AY AF Nagaraja, Sridevi Wallqvist, Anders Reifman, Jaques Mitrophanov, Alexander Y. TI Computational Approach To Characterize Causative Factors and Molecular Indicators of Chronic Wound Inflammation SO JOURNAL OF IMMUNOLOGY LA English DT Article ID GROWTH-FACTOR-BETA; TGF-BETA; IN-SILICO; PROINFLAMMATORY CYTOKINES; APOPTOTIC NEUTROPHILS; MATHEMATICAL-MODEL; MACROPHAGE; MICE; MECHANISMS; MONOCYTES AB Chronic inflammation is rapidly becoming recognized as a key contributor to numerous pathologies. Despite detailed investigations, understanding of the molecular mechanisms regulating inflammation is incomplete. Knowledge of such critical regulatory processes and informative indicators of chronic inflammation is necessary for efficacious therapeutic interventions and diagnostic support to clinicians. We used a computational modeling approach to elucidate the critical factors responsible for chronic inflammation and to identify robust molecular indicators of chronic inflammatory conditions. Our kinetic model successfully captured experimentally observed cell and cytokine dynamics for both acute and chronic inflammatory responses. Using sensitivity analysis, we identified macrophage influx and efflux rate modulation as the strongest inducing factor of chronic inflammation for a wide range of scenarios. Moreover, our model predicted that, among all major inflammatory mediators, IL-6, TGF-beta, and PDGF may generally be considered the most sensitive and robust indicators of chronic inflammation, which is supported by existing, but limited, experimental evidence. C1 [Nagaraja, Sridevi; Wallqvist, Anders; Reifman, Jaques; Mitrophanov, Alexander Y.] US Army Med Res & Mat Command, Telemed & Adv Technol Res Ctr, Dept Def Biotechnol High Performance Comp Softwar, Ft Detrick, MD 21702 USA. RP Reifman, J (reprint author), ATTN MCMR TT, US Army Med Res & Mat Command, Telemed & Adv Technol Res Ctr, Dept Def Biotechnol High Performance Comp Softwar, 504 Scott St, Ft Detrick, MD 21702 USA. EM jaques.reifman.civ@mail.mil OI wallqvist, anders/0000-0002-9775-7469 FU Clinical and Rehabilitative Medicine Research Program of the U.S. Army Medical Research and Materiel Command FX This work was supported by the Clinical and Rehabilitative Medicine Research Program of the U.S. Army Medical Research and Materiel Command. NR 88 TC 11 Z9 11 U1 0 U2 7 PU AMER ASSOC IMMUNOLOGISTS PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 USA SN 0022-1767 EI 1550-6606 J9 J IMMUNOL JI J. Immunol. PD FEB 15 PY 2014 VL 192 IS 4 BP 1824 EP 1834 DI 10.4049/jimmunol.1302481 PG 11 WC Immunology SC Immunology GA AA7HB UT WOS:000331267200050 PM 24453259 ER PT J AU Pethel, SD Hahs, DW AF Pethel, S. D. Hahs, D. W. TI Exact significance test for Markov order SO PHYSICA D-NONLINEAR PHENOMENA LA English DT Article DE Markov order; Hypothesis test; Whittle's formula ID CHAIN; MODEL; INFERENCE AB We describe an exact significance test of the null hypothesis that a Markov chain is nth order. The procedure utilizes surrogate data to yield an exact test statistic distribution valid for any sample size. Surrogate data are generated using a novel algorithm that guarantees, per shot, a uniform sampling from the set of sequences that exactly match the nth order properties of the observed data. Using the test, the Markov order of Tel Aviv rainfall data is examined. Published by Elsevier B.V. C1 [Pethel, S. D.] US Army RDECOM, RDMR WDS W, Redstone Arsenal, AL 35898 USA. [Hahs, D. W.] Torch Technol Inc, Huntsville, AL 35802 USA. RP Pethel, SD (reprint author), US Army RDECOM, RDMR WDS W, Redstone Arsenal, AL 35898 USA. EM shawn.pethel@us.army.mil; daniel.hahs@us.army.mil NR 16 TC 5 Z9 5 U1 1 U2 2 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0167-2789 EI 1872-8022 J9 PHYSICA D JI Physica D PD FEB 15 PY 2014 VL 269 BP 42 EP 47 DI 10.1016/j.physd.2013.11.014 PG 6 WC Mathematics, Applied; Physics, Multidisciplinary; Physics, Mathematical SC Mathematics; Physics GA AB0PT UT WOS:000331495300005 ER PT J AU Wang, WY Shang, SL Wang, Y Darling, KA Kecskes, LJ Mathaudhu, SN Hui, XD Liu, ZK AF Wang, William Yi Shang, Shun Li Wang, Yi Darling, Kristopher A. Kecskes, Laszlo J. Mathaudhu, Suveen N. Hui, Xi Dong Liu, Zi-Kui TI Electronic structures of long periodic stacking order structures in Mg: A first-principles study SO JOURNAL OF ALLOYS AND COMPOUNDS LA English DT Article DE Mg alloys; Stacking faults; Long period stacking order (LPSO); Deformation electron density ID TOTAL-ENERGY CALCULATIONS; WAVE BASIS-SET; Y-ZN ALLOYS; MECHANICAL-PROPERTIES; ELASTIC CONSTANTS; MAGNESIUM ALLOYS; MG97ZN1Y2 ALLOY; 14H; MICROSTRUCTURE; STRENGTH AB Long period stacking order (LPSO) structures, such as 6H, 10H, 14H, 18R and 24R, play significant roles in enhancing the mechanical properties of Mg alloys and have been largely investigated separately. In the present work, through detailed investigations of deformation electron density, we show that the electron structures of 10H, 14H, 18R and 24R LPSO structures in Mg originate from those of deformation stacking faults in Mg, and their formation energies can be scaled with respect to formation energy and the number of layers of deformation stacking faults, while the electron structure and formation energy of the 6H LPSO structure are between those of deformation and growth stacking faults. The simulated images of high resolution transmission electron microscopy compare well with experimental observed ones. The understanding of LPSO structures in Mg enables future quantitative investigations of effects of alloying elements on properties of LPSO structures and Mg alloys. (C) 2013 Elsevier B.V. All rights reserved. C1 [Wang, William Yi; Shang, Shun Li; Wang, Yi; Liu, Zi-Kui] Penn State Univ, Dept Mat Sci & Engn, University Pk, PA 16802 USA. [Wang, William Yi; Darling, Kristopher A.; Hui, Xi Dong] Univ Sci & Technol Beijing, State Key Lab Adv Met & Mat, Beijing 100083, Peoples R China. [Kecskes, Laszlo J.] US Army Res Lab, Weap & Mat Res Directorate, RDRL WMM B, Aberdeen Proving Ground, MD 21005 USA. [Mathaudhu, Suveen N.] US Army Res Off, Div Mat Sci, Res Triangle Pk, NC 27709 USA. RP Wang, WY (reprint author), Penn State Univ, Dept Mat Sci & Engn, University Pk, PA 16802 USA. EM yuw129@psu.edu; dr.liu@psu.edu RI Shang, Shun-Li/A-6564-2009; Wang, William Yi/F-8212-2011; Wang, Yi/D-1032-2013; Kecskes, Laszlo/F-6880-2014; Hui, Xidong/A-1741-2010; Mathaudhu, Suveen/B-4192-2009; Liu, Zi-Kui/A-8196-2009 OI Shang, Shun-Li/0000-0002-6524-8897; Wang, William Yi/0000-0002-8814-525X; Kecskes, Laszlo/0000-0002-1342-3729; Liu, Zi-Kui/0000-0003-3346-3696 FU U.S. Army Research Lab [W911NF-08-2-0064]; National Science Foundation in the United States [DMR-1006557]; National Natural Science Foundation of China [51071018]; China Scholarship Council; American Academic Exchange Service [[2008] 3072]; NSF [OCI-0821527] FX This work was financially supported by the U.S. Army Research Lab (Project No. W911NF-08-2-0064) and the National Science Foundation (Grant No. DMR-1006557) in the United States, National Natural Science Foundation of China (Grant No. 51071018). W.Y. Wang acknowledges the support from the Project Based Personnel Exchange Program with China Scholarship Council and American Academic Exchange Service ([2008] 3072). First-principles calculations were carried out on the LION clusters supported by the Materials Simulation Center and the Research Computing and Cyberinfrastructure unit at the Pennsylvania State University. Calculations were also carried out on the CyberStar cluster funded by NSF through Grant OCI-0821527, and partially on resources of the National Supercomputer Center in Shenzhen. NR 54 TC 12 Z9 12 U1 9 U2 69 PU ELSEVIER SCIENCE SA PI LAUSANNE PA PO BOX 564, 1001 LAUSANNE, SWITZERLAND SN 0925-8388 EI 1873-4669 J9 J ALLOY COMPD JI J. Alloy. Compd. PD FEB 15 PY 2014 VL 586 BP 656 EP 662 DI 10.1016/j.jallcom.2013.10.068 PG 7 WC Chemistry, Physical; Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering SC Chemistry; Materials Science; Metallurgy & Metallurgical Engineering GA 291UT UT WOS:000329856800105 ER PT J AU Chromy, BA Eldridge, A Forsberg, JA Brown, TS Kirkup, BC Elster, E Luciw, P AF Chromy, Brett A. Eldridge, Angela Forsberg, Jonathan A. Brown, Trevor S. Kirkup, Benjamin C. Elster, Eric Luciw, Paul TI Proteomic sample preparation for blast wound characterization SO PROTEOME SCIENCE LA English DT Article DE Blast wound; Proteomics; 2-D DIGE; Wound effluent; Biomarker discovery; Serum; High abundant protein removal ID DIFFERENTIAL GEL-ELECTROPHORESIS; ABUNDANCE PROTEIN DEPLETION; HUMAN SERUM; PLASMA-PROTEINS; BIOMARKER DISCOVERY; EXPRESSION; INJURIES; CYTOKINE; FLUID AB Background: Blast wounds often involve diverse tissue types and require substantial time and treatment for appropriate healing. Some of these subsequent wounds become colonized with bacteria requiring a better understanding of how the host responds to these bacteria and what proteomic factors contribute wound healing outcome. In addition, using reliable and effective proteomic sample preparation procedures can lead to novel biomarkers for improved diagnosis and therapy. Results: To address this need, suitable sample preparation for 2-D DIGE proteomic characterization of wound effluent and serum samples from combat-wounded patients was investigated. Initial evaluation of crude effluent and serum proved the necessity of high abundant protein depletion. Subsequently, both samples were successfully depleted using Agilent Multiple Affinity Removal system and showed greatly improved 2-D spot maps, comprising 1,800 and 1,200 protein spots, respectively. Conclusion: High abundant protein removal was necessary for both wound effluent and serum. This is the first study to show a successful method for high abundant protein depletion from wound effluent which is compatible with downstream 2-D DIGE analysis. This development allows for improved biomarker discovery in wound effluent and serum samples. C1 [Chromy, Brett A.; Eldridge, Angela; Luciw, Paul] Univ Calif Davis, Dept Pathol & Lab Med, Sch Med, Davis, CA 95616 USA. [Eldridge, Angela; Luciw, Paul] Univ Calif Davis, Ctr Comparat Med, Davis, CA 95616 USA. [Forsberg, Jonathan A.] Naval Med Res Ctr, Regenerat Med Dept, Silver Spring, MD USA. [Forsberg, Jonathan A.] Natl Mil Med Ctr, Dept Orthopaed, Bethesda, MD USA. [Brown, Trevor S.; Kirkup, Benjamin C.; Elster, Eric] Walter Reed Army Inst Res, Dept Wound Infect, Silver Spring, MD USA. [Kirkup, Benjamin C.] Uniformed Serv Univ Hlth Sci, F Edward Hebert Sch Med, Dept Med, Bethesda, MD 20814 USA. [Forsberg, Jonathan A.; Elster, Eric] Uniformed Serv Univ Hlth Sci, Norman M Rich Dept Surg, Bethesda, MD 20814 USA. [Forsberg, Jonathan A.; Elster, Eric] Uniformed Serv Univ Hlth Sci, Surg Crit Care Inst, Bethesda, MD 20814 USA. RP Chromy, BA (reprint author), Univ Calif Davis, Dept Pathol & Lab Med, Sch Med, Davis, CA 95616 USA. EM brett.chromy@ucdmc.ucdavis.edu RI Brown, Trevor/K-4703-2012; Kirkup, Benjamin/C-3610-2009; Brown, Trevor/F-7392-2015 OI Brown, Trevor/0000-0001-7042-785X; Kirkup, Benjamin/0000-0002-8722-6218; Brown, Trevor/0000-0001-7042-785X FU U.S. Army Medical Research and Materiel Command [MIPR1EO89M1115]; U.S. Army Medical Research Acquisition Activity [MD 21702-5014]; Proteomics Initiative of the Department of Pathology and Laboratory Medicine at U.C. Davis FX The project depicted was sponsored by the U.S. Army Medical Research and Materiel Command (Award number: MIPR1EO89M1115). The U.S. Army Medical Research Acquisition Activity (820 Chandler Street, Fort Detrick MD 21702-5014) is the awarding and administering acquisition office. Partial funding for this project was also provided by the Proteomics Initiative of the Department of Pathology and Laboratory Medicine at U.C. Davis. We gratefully acknowledge Crystal Jaing, Nicholas Be, and Ray Lenhoff for very helpful discussions. The opinions or assertions contained herein are the private views of the authors, and are not to be construed as official, or as reflecting the position or policy of the government, including the Departments of the Army, Navy, or Defense. NR 26 TC 3 Z9 3 U1 0 U2 7 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1477-5956 J9 PROTEOME SCI JI Proteome Sci. PD FEB 14 PY 2014 VL 12 AR 10 DI 10.1186/1477-5956-12-10 PG 8 WC Biochemical Research Methods SC Biochemistry & Molecular Biology GA AC8RH UT WOS:000332800900001 PM 24529238 ER PT J AU Rudin, S Rupper, G Gutin, A Shur, M AF Rudin, S. Rupper, G. Gutin, A. Shur, M. TI Theory and measurement of plasmonic terahertz detector response to large signals SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID FIELD-EFFECT TRANSISTOR; RADIATION; OSCILLATIONS; MECHANISM; FLUID; SPICE AB Electron gas in the conduction channel of a Field Effect Transistor (FET) can support collective plasma oscillations tunable by the gate voltage. In the Dyakonov-Shur terahertz (THz) detector, nonlinearities in the plasma wave propagation in the gated channel of a FET lead to a constant source-to-drain voltage providing the detector output. We present the detector theory in the frame of the hydrodynamic model using the electron plasma Navier-Stokes and thermal transport equations, thus fully accounting for the hydrodynamic non-linearity, the viscosity, and pressure gradients in the detector response. Both resonant and broadband operations of the high electron mobility transistor (HEMT) based plasmonic detectors are described by this model. The relation between the electron channel density and gate voltage was modeled by the unified charge control model applicable both above and below the threshold voltage. The theoretical results are compared with the response measured in the short channel InGaAs HEMT and the analytical approximation. The THz source was operating at 1.63 THz, and the response was measured at varying signal intensities. The response of the detector operated in the open drain mode was measured above and below the threshold, and the theoretical and experimental results are shown to be in good agreement. (C) 2014 AIP Publishing LLC. C1 [Rudin, S.; Rupper, G.] Army Res Lab, Adelphi, MD 20783 USA. [Gutin, A.; Shur, M.] Rensselaer Polytech Inst, Troy, NY 12180 USA. RP Rudin, S (reprint author), Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. RI Shur, Michael/A-4374-2016 OI Shur, Michael/0000-0003-0976-6232 FU DOE University PV Process and Product Development Program [DE-FG36-08GO18067] FX The Authors would like to thank Dr. David Strickler from NSG (Pilkington NA) Toledo, OH, for supplying low-iron, SnO2:F-coated, soda-lime glass substrates. This work was partially supported by the DOE University PV Process and Product Development Program under Contract No. DE-FG36-08GO18067. NR 30 TC 10 Z9 10 U1 3 U2 32 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0021-8979 EI 1089-7550 J9 J APPL PHYS JI J. Appl. Phys. PD FEB 14 PY 2014 VL 115 IS 6 AR 064503 DI 10.1063/1.4862808 PG 11 WC Physics, Applied SC Physics GA AB5PC UT WOS:000331839800053 ER PT J AU Samy, RP Kandasamy, M Gopalakrishnakone, P Stiles, BG Rowan, EG Becker, D Shanmugam, MK Sethi, G Chow, VTK AF Samy, Ramar Perumal Kandasamy, Matheswaran Gopalakrishnakone, Ponnampalam Stiles, Bradley G. Rowan, Edward G. Becker, David Shanmugam, Muthu K. Sethi, Gautam Chow, Vincent T. K. TI Wound Healing Activity and Mechanisms of Action of an Antibacterial Protein from the Venom of the Eastern Diamondback Rattlesnake (Crotalus adamanteus) SO PLOS ONE LA English DT Article ID ENDOTHELIAL GROWTH-FACTOR; LYSINE-49 PHOSPHOLIPASE A(2); TERRIFICUS SNAKE-VENOM; NF-KAPPA-B; ANTIMICROBIAL ACTIVITY; PHARMACOLOGICAL PROPERTIES; ENZYMATIC-ACTIVITY; MAMMALIAN-CELLS; TERMINAL REGION; MYOTOXIN-II AB Basic phospholipase A(2) was identified from the venom of the eastern diamondback rattlesnake. The Crotalus adamanteus toxin-II (CaTx-II) induced bactericidal effects (7.8 mu g/ml) on Staphylococcus aureus, while on Burkholderia pseudomallei (KHW), and Enterobacter aerogenes were killed at 15.6 mu g/ml. CaTx-II caused pore formation and membrane damaging effects on the bacterial cell wall. CaTx-II was not cytotoxic on lung (MRC-5), skin fibroblast (HEPK) cells and in mice. CaTx-II-treated mice showed significant wound closure and complete healing by 16 days as compared to untreated controls (**P<0.01). Histological examination revealed enhanced collagen synthesis and neovascularization after treatment with CaTx-II versus 2% Fusidic Acid ointment (FAO) treated controls. Measurement of tissue cytokines revealed that interleukin-1 beta (IL-1 beta) expression in CaTx-II treated mice was significantly suppressed versus untreated controls. In contrast, cytokines involved in wound healing and cell migration i.e., monocyte chemotactic protein-1 (MCP-1), fibroblast growth factor-basic (FGF-b), chemokine (KC), granulocyte-macrophage colony-stimulating factor (GM-CSF) were significantly enhanced in CaTx-II treated mice, but not in the controls. CaTx-II also modulated nuclear factor-kappa B (NF-kappa B) activation during skin wound healing. The CaTx-II protein highlights distinct snake proteins as a potential source of novel antimicrobial agents with significant therapeutic application for bacterial skin infections. C1 [Samy, Ramar Perumal; Gopalakrishnakone, Ponnampalam] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Anat, Venom & Toxin Res Programme, Singapore 117595, Singapore. [Samy, Ramar Perumal; Chow, Vincent T. K.] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Microbiol, Infect Dis Programme, Singapore 117595, Singapore. [Kandasamy, Matheswaran] Agcy Sci Technol & Res, Singapore Inst Clin Sci, Brenner Ctr Mol Med, Infect Immun Programme, Singapore, Singapore. [Stiles, Bradley G.] US Army Med Res, Integrated Toxicol Div, Inst Infect Dis, Ft Detrick, MD USA. [Rowan, Edward G.] Univ Strathclyde, Strathclyde Inst Pharm & Biomed Sci, Glasgow, Lanark, Scotland. [Becker, David] UCL, Dept Anat & Dev Biol, London, England. [Shanmugam, Muthu K.; Sethi, Gautam] Natl Univ Singapore, Yong Loo Lin Sch Med, Clin Res Ctr, Dept Pharmacol, Singapore 117595, Singapore. RP Samy, RP (reprint author), Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Anat, Venom & Toxin Res Programme, Singapore 117595, Singapore. EM rperumalsamy@yahoo.co.uk OI Kandasamy, Matheswaran/0000-0001-7734-4600 FU Economic Development Board (EDB), Singapore [R-181-000-110-144]; MOE Tier I FX The authors thank Dr. Naidu for providing cells (skin fibroblast) and technical support in performing the cytotoxicity assay. The authors are thankful to the Economic Development Board (EDB), Singapore, for financial support by Proof of Concept (Grant No: R-181-000-110-144). This work was also supported in part by a grant from MOE Tier I to Dr. Gautam Sethi. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. NR 78 TC 10 Z9 10 U1 0 U2 8 PU PUBLIC LIBRARY SCIENCE PI SAN FRANCISCO PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA SN 1932-6203 J9 PLOS ONE JI PLoS One PD FEB 14 PY 2014 VL 9 IS 2 AR e80199 DI 10.1371/journal.pone.0080199 PG 16 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA AA7IR UT WOS:000331271500001 PM 24551028 ER PT J AU Lau, TM Gwin, JT Ferris, DP AF Lau, Troy M. Gwin, Joseph T. Ferris, Daniel P. TI Walking reduces sensorimotor network connectivity compared to standing SO JOURNAL OF NEUROENGINEERING AND REHABILITATION LA English DT Article DE EEG (electroencephalography); Walking; Connectivity; Multi-tasking; Brain ID INDEPENDENT COMPONENT ANALYSIS; SPINAL-CORD-INJURY; CORTICAL ACTIVATION; BRAIN-FUNCTION; DEFAULT MODE; GAIT; EEG; LOCOMOTION; HUMANS; BLIND AB Background: Considerable effort has been devoted to mapping the functional and effective connectivity of the human brain, but these efforts have largely been limited to tasks involving stationary subjects. Recent advances with high-density electroencephalography (EEG) and Independent Components Analysis (ICA) have enabled study of electrocortical activity during human locomotion. The goal of this work was to measure the effective connectivity of cortical activity during human standing and walking. Methods: We recorded 248-channels of EEG as eight young healthy subjects stood and walked on a treadmill both while performing a visual oddball discrimination task and not performing the task. ICA parsed underlying electrocortical, electromyographic, and artifact sources from the EEG signals. Inverse source modeling methods and clustering algorithms localized posterior, anterior, prefrontal, left sensorimotor, and right sensorimotor clusters of electrocortical sources across subjects. We applied a directional measure of connectivity, conditional Granger causality, to determine the effective connectivity between electrocortical sources. Results: Connections involving sensorimotor clusters were weaker for walking than standing regardless of whether the subject was performing the simultaneous cognitive task or not. This finding supports the idea that cortical involvement during standing is greater than during walking, possibly because spinal neural networks play a greater role in locomotor control than standing control. Conversely, effective connectivity involving non-sensorimotor areas was stronger for walking than standing when subjects were engaged in the simultaneous cognitive task. Conclusions: Our results suggest that standing results in greater functional connectivity between sensorimotor cortical areas than walking does. Greater cognitive attention to standing posture than to walking control could be one interpretation of that finding. These techniques could be applied to clinical populations during gait to better investigate neural substrates involved in mobility disorders. C1 [Lau, Troy M.; Gwin, Joseph T.; Ferris, Daniel P.] Univ Michigan, Sch Kinesiol, Human Neuromech Lab, Ann Arbor, MI 48109 USA. [Lau, Troy M.] US Army Res Lab, Human Res & Engn Directorate, Translat Neurosci Branch, Aberdeen Proving Ground, MD 21005 USA. RP Lau, TM (reprint author), Univ Michigan, Sch Kinesiol, Human Neuromech Lab, Ann Arbor, MI 48109 USA. EM troylau@gmail.com RI Ferris, Daniel/A-9624-2008 OI Ferris, Daniel/0000-0001-6373-6021 FU US ARL CTA on Cognition and Neuroergonomics [F029121]; NDSEG fellowship FX The authors would like to thank Klauss Gramann and Scott Makeig for important contributions on the experimental design. This research was supported by funding from the US ARL CTA on Cognition and Neuroergonomics (F029121) and a NDSEG fellowship to JTG. NR 53 TC 8 Z9 8 U1 2 U2 15 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1743-0003 J9 J NEUROENG REHABIL JI J. NeuroEng. Rehabil. PD FEB 13 PY 2014 VL 11 AR 14 DI 10.1186/1743-0003-11-14 PG 10 WC Engineering, Biomedical; Neurosciences; Rehabilitation SC Engineering; Neurosciences & Neurology; Rehabilitation GA AF4QP UT WOS:000334699200001 PM 24524394 ER PT J AU Tsendra, O Scott, AM Gorb, L Boese, AD Hill, FC Ilchenko, MM Leszczynska, D Leszczynski, J AF Tsendra, Oksana Scott, Andrea Michalkova Gorb, Leonid Boese, A. Daniel Hill, Frances C. Ilchenko, Mykola M. Leszczynska, Danuta Leszczynski, Jerzy TI Adsorption of Nitrogen-Containing Compounds on the (100) alpha-Quartz Surface: Ab Initio Cluster Approach SO JOURNAL OF PHYSICAL CHEMISTRY C LA English DT Article ID ELECTRON-DENSITY PROPERTIES; SILICA SURFACE; NONCOVALENT INTERACTIONS; CLAY-MINERALS; BASIS-SETS; FUNCTIONAL THEORY; N-ALKANES; X-RAY; HYDROGEN; ENERGIES AB A cluster approach extended to the ONIOM methodology has been applied using several density functionals and Moller-Plesset perturbation theory (MP2) to simulate the adsorption of selected nitrogen-containing compounds [NCCs, 2,4,6-trinitrotoluene (TNT), 2,4-dinitrotoluene (DNT), 2,4-dinitroanisole (DNAN), and 3-nitro-1,2,4-triazole-5-one (NTO)] on the hydroxyated (100) surface of a-quartz. The structural properties were calculated using the M06-2X functional and 6-31G(d,p) basis set. The M06-2X-D3, PBE-D3, and MP2 methods were used to calculate the adsorption energies. Results have been compared with the data from other studies of adsorption of compounds of similar nature on silica. Effect of deformation of the silica surface and adsorbates on the binding energy values was also studied. The atoms in molecules (AIM) analysis was employed to characterize the adsorbate-adsorbent binding and to calculate the bond energies. The silica surface shows different sorption affinity toward the chemicals considered depending on their electronic structure. All target NCCs are physisorbed on the modeled silica surface. Adsorption occurs due to the formation of multiple hydrogen bonds between the functional groups of NCCs and surface silanol groups. Parallel orientation of NCCs interacting with the silica surface was found to be favorable when compared with perpendicularly oriented NCCs. NTO was found to be the most strongly adsorbed on the silica surface among all of the considered compounds. Dispersion correction was shown to play an important role in the DFT calculations of the adsorption energies of silica-NCC systems. C1 [Tsendra, Oksana; Leszczynski, Jerzy] Jackson State Univ, Dept Chem & Biochem, Interdisciplinary Nanotox Ctr, Jackson, MS 39217 USA. [Tsendra, Oksana] Natl Acad Sci Ukraine, Chuiko Inst Surface Chem, UA-03164 Kiev, Ukraine. [Scott, Andrea Michalkova; Hill, Frances C.; Leszczynski, Jerzy] US Army Engineer Res & Dev Ctr ERDC, Vicksburg, MS 39180 USA. [Gorb, Leonid] Badger Tech Serv LLC, Vicksburg, MS 39180 USA. [Boese, A. Daniel] Univ Potsdam, Dept Chem, D-14476 Potsdam, Germany. [Ilchenko, Mykola M.] Natl Acad Sci Ukraine, Inst Mol Biol & Genet, UA-03143 Kiev, Ukraine. [Leszczynska, Danuta] Jackson State Univ, Dept Civil & Environm Engn, Jackson, MS 39217 USA. RP Scott, AM (reprint author), US Army Engineer Res & Dev Ctr ERDC, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM andrea.m.scott@usace.army.mil FU High Performance Computing Distributed Shared Resource Center at the ERDC (Vicksburg, MS); Office of Naval Research [N00034-03-1-0116]; Environmental Quality Technology Program of the United States Army Corps of Engineers by the US Army ERDC FX This work was facilitated by support from the High Performance Computing Distributed Shared Resource Center at the ERDC (Vicksburg, MS) and the Office of Naval Research Grant N00034-03-1-0116. The use of trade, product, or firm names in this report is for descriptive purposes only and does not imply endorsement by the U.S. Government. Results in this study were funded and obtained from research conducted under the Environmental Quality Technology Program of the United States Army Corps of Engineers by the US Army ERDC. Permission was granted by the Chief of Engineers to publish this information. The findings of this report are not to be construed as an official Department of the Army position unless so designated by other authorized documents. A.D.B. would also like to thank Professor Saalfrank (University of Potsdam) for providing some computational time. NR 92 TC 6 Z9 6 U1 2 U2 39 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1932-7447 J9 J PHYS CHEM C JI J. Phys. Chem. C PD FEB 13 PY 2014 VL 118 IS 6 BP 3023 EP 3034 DI 10.1021/jp406827h PG 12 WC Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Chemistry; Science & Technology - Other Topics; Materials Science GA AB0PA UT WOS:000331493400015 ER PT J AU Aryanpour, K Roberts, A Sandhu, A Rathore, R Shuka, A Mazumdar, S AF Aryanpour, Karan Roberts, Adam Sandhu, Arvinder Rathore, Rajendra Shuka, Alok Mazumdar, Sumit TI Subgap Two-Photon States in Polycyclic Aromatic Hydrocarbons: Evidence for Strong Electron Correlations SO JOURNAL OF PHYSICAL CHEMISTRY C LA English DT Article ID LYING EXCITED-STATES; EVEN-PARITY STATES; CONJUGATED POLYMERS; LINEAR POLYENES; SINGLE-BEAM; EXCITATIONS; GRAPHENE; POLYACETYLENES; ABSORPTION; TRANSITION AB Strong electron correlation effects in the photophysics of quasi-one-dimensional a-conjugated organic systems such as polyenes, polyacetylenes, polydiacetylenes, etc., have been extensively studied. Far less is known on correlation effects in two-dimensional pi-conjugated systems. Here we present theoretical and experimental evidence for moderate repulsive electron electron interactions in a. number of finite polycyclic aromatic hydrocarbon molecules with D-6h symmetry. We show that the excited state orderings in these molecules are reversed relative to that expected within one-electron and mean-field theories. Our results reflect similarities as well as differences in the role and magnitude of electron correlation effects in these two-dimensional molecules compared to those in polyenes. C1 [Aryanpour, Karan; Sandhu, Arvinder; Mazumdar, Sumit] Univ Arizona, Dept Phys, Tucson, AZ 85721 USA. [Roberts, Adam] US Army Aviat & Missile Res, Ctr Dev & Engn, Huntsville, AL 35898 USA. [Roberts, Adam; Sandhu, Arvinder; Mazumdar, Sumit] Univ Arizona, Coll Opt Sci, Tucson, AZ 85721 USA. [Rathore, Rajendra] Marquette Univ, Dept Chem, Milwaukee, WI 53201 USA. [Shuka, Alok] Indian Inst Technol, Dept Phys, Bombay 400076, Maharashtra, India. RP Aryanpour, K (reprint author), Univ Arizona, Dept Phys, Tucson, AZ 85721 USA. EM karana@physics.arizona.edu FU NSF [CHE-1151475]; DoD SMART program; Indo-US Science and Technology Forum [37-2012/2013-14] FX This work was supported by NSF Grant No. CHE-1151475. A.R. acknowledges the support from the DoD SMART program. A.Sh. and S.M. acknowledge support from the Indo-US Science and Technology Forum Award 37-2012/2013-14. NR 57 TC 9 Z9 9 U1 5 U2 29 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1932-7447 J9 J PHYS CHEM C JI J. Phys. Chem. C PD FEB 13 PY 2014 VL 118 IS 6 BP 3331 EP 3339 DI 10.1021/jp410793r PG 9 WC Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Chemistry; Science & Technology - Other Topics; Materials Science GA AB0PA UT WOS:000331493400052 ER PT J AU Ferreyra, GA Elinoff, JM Demirkale, CY Starost, MF Buckley, M Munson, PJ Krakauer, T Danner, RL AF Ferreyra, Gabriela A. Elinoff, Jason M. Demirkale, Cumhur Y. Starost, Matthew F. Buckley, Marilyn Munson, Peter J. Krakauer, Teresa Danner, Robert L. TI Late Multiple Organ Surge in Interferon-Regulated Target Genes Characterizes Staphylococcal Enterotoxin B Lethality SO PLOS ONE LA English DT Article ID TOXIC-SHOCK-SYNDROME; A STREPTOCOCCAL INFECTIONS; MONKEYS MACACA-MULATTA; INNATE IMMUNE-RESPONSE; HUMAN T-CELLS; DENDRITIC CELLS; I INTERFERON; BACTERIAL SUPERANTIGENS; INTRANASAL EXPOSURE; ENDOTHELIAL-CELLS AB Background: Bacterial superantigens are virulence factors that cause toxic shock syndrome. Here, the genome-wide, temporal response of mice to lethal intranasal staphylococcal enterotoxin B (SEB) challenge was investigated in six tissues. Results: The earliest responses and largest number of affected genes occurred in peripheral blood mononuclear cells (PBMC), spleen, and lung tissues with the highest content of both T-cells and monocyte/macrophages, the direct cellular targets of SEB. In contrast, the response of liver, kidney, and heart was delayed and involved fewer genes, but revealed a dominant genetic program that was seen in all 6 tissues. Many of the 85 uniquely annotated transcripts participating in this shared genomic response have not been previously linked to SEB. Nine of the 85 genes were subsequently confirmed by RTPCR in every tissue/organ at 24 h. These 85 transcripts, up-regulated in all tissues, annotated to the interferon (IFN)/antiviralresponse and included genes belonging to the DNA/RNA sensing system, DNA damage repair, the immunoproteasome, and the ER/metabolic stress-response and apoptosis pathways. Overall, this shared program was identified as a type I and II interferon (IFN)-response and the promoters of these genes were highly enriched for IFN regulatory matrices. Several genes whose secreted products induce the IFN pathway were up-regulated at early time points in PBMCs, spleen, and/or lung. Furthermore, IFN regulatory factors including Irf1, Irf7 and Irf8, and Zbp1, a DNA sensor/transcription factor that can directly elicit an IFN innate immune response, participated in this host-wide SEB signature. Conclusion: Global gene-expression changes across multiple organs implicated a host-wide IFN-response in SEB-induced death. Therapies aimed at IFN-associated innate immunity may improve outcome in toxic shock syndromes. C1 [Ferreyra, Gabriela A.; Elinoff, Jason M.; Danner, Robert L.] NIH, Funct Genom & Prote Facil, Dept Crit Care Med, Clin Res Ctr, Bethesda, MD 20892 USA. [Demirkale, Cumhur Y.; Munson, Peter J.] NIH, Math & Stat Comp Lab, Ctr Informat Technol, Bethesda, MD 20892 USA. [Starost, Matthew F.] NIH, Div Vet Resources, Off Res Serv, Bethesda, MD 20892 USA. [Buckley, Marilyn; Krakauer, Teresa] US Army Med Res Inst Infect Dis, Integrated Toxicol Div, Ft Detrick, MD 21702 USA. RP Krakauer, T (reprint author), US Army Med Res Inst Infect Dis, Integrated Toxicol Div, Ft Detrick, MD 21702 USA. EM teresa.krakauer@us.army.mil; rdanner@nih.gov FU Defense Threat Reduction Agency [DTRA 3.10035]; Intramural Research Program of the Critical Care Medicine Department, NIH Clinical Center FX This research was entirely funded by The Defense Threat Reduction Agency (#DTRA 3.10035) and the Intramural Research Program of the Critical Care Medicine Department, NIH Clinical Center. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. NR 84 TC 7 Z9 7 U1 0 U2 5 PU PUBLIC LIBRARY SCIENCE PI SAN FRANCISCO PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA SN 1932-6203 J9 PLOS ONE JI PLoS One PD FEB 13 PY 2014 VL 9 IS 2 AR e88756 DI 10.1371/journal.pone.0088756 PG 18 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA AA7GP UT WOS:000331266000062 PM 24551153 ER PT J AU Ingraham, JM Deng, ZD Martinez, JJ Trumbo, BA Mueller, RP Weiland, MA AF Ingraham, John M. Deng, Z. Daniel Martinez, Jayson J. Trumbo, Bradly A. Mueller, Robert P. Weiland, Mark A. TI Feasibility of Tracking Fish with Acoustic Transmitters in the Ice Harbor Dam Tailrace SO SCIENTIFIC REPORTS LA English DT Article ID TELEMETRY SYSTEM; INSTRUMENTATION; DESIGN AB The Juvenile Salmon Acoustic Telemetry System (JSATS) has been used at many dams but has never been deployed in the near-dam tailrace environment. The use of JSATS in the tailrace is of interest to fishery managers to evaluate downstream passage behavior of juvenile salmonids and dam approach behavior of upstream migrating adult salmon and lamprey. The acoustic noise level and detection range of JSATS were studied to determine the feasibility of deploying JSATS in the Ice Harbor Dam tailrace. The noise level measured from the powerhouse deck was less than 104 dB re 1 mu Pa except for the turbine outlet near the spillway, and 350 mdownstream of the dam, the noise level was less than 106 dB. The measured noise levels would allow a theoretical detection range of 100 m to 350 m and 85 m to 320 m, respectively. Validation experiments showed that the detection range is 113 to 184 m using hydrophones deployed from the powerhouse deck and 148 m using hydrophones deployed 500 m downstream of the dam. C1 [Ingraham, John M.; Deng, Z. Daniel; Martinez, Jayson J.; Mueller, Robert P.; Weiland, Mark A.] Pacific NW Natl Lab, Energy & Environm Directorate, Richland, WA 99352 USA. [Trumbo, Bradly A.] US Army Corps Engineers, Walla Walla, WA USA. RP Deng, ZD (reprint author), Pacific NW Natl Lab, Energy & Environm Directorate, Richland, WA 99352 USA. EM zhiqun.deng@pnnl.gov RI Deng, Daniel/A-9536-2011 OI Deng, Daniel/0000-0002-8300-8766 FU U.S. Army Corps of Engineers (USACE) FX This research was funded by the U.S. Army Corps of Engineers (USACE). We greatly appreciate the assistance of USACE staff members including Martin Ahmann, Derek Fryer, Marvin Shutters, Jon Renholds, Mark Plummer, Trevor Mclaen, and Mike Trusty. Critical assistance also was provided by many staff members of Pacific Northwest National Laboratory, including Tylor Abel, Evan Arntzen, Brian Bellgraph, Zach Booth, Tom Carlson, Katrina Cook, Cary Counts, Eric Fischer, Tao Fu, Amanda Hanson, Ryan Harnish, Julie Hughes, Xinya Li, Brian Jeide, Ryan Klett, Kyle Larson, Kathy Lavender, Geoff McMichael, Caleb Price, Huiying Ren, Jason Reynolds, John Serkowski, John Stephenson, Craig Swartout, Scott Titzler, Jinshan Xu, and Yong Yuan. NR 14 TC 1 Z9 1 U1 6 U2 19 PU NATURE PUBLISHING GROUP PI LONDON PA MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND SN 2045-2322 J9 SCI REP-UK JI Sci Rep PD FEB 13 PY 2014 VL 4 AR 4090 DI 10.1038/srep04090 PG 8 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA AA7QU UT WOS:000331292800002 PM 24522516 ER PT J AU Goo, YK Seo, EJ Choi, YK Shin, HI Sattabongkot, J Ji, SY Chong, CK Cho, SH Lee, WJ Kim, JY AF Goo, Youn-Kyoung Seo, Eun-Jeong Choi, Yeon-Kyung Shin, Hyun-Il Sattabongkot, Jetsumon Ji, So-Young Chong, Chom-Kyu Cho, Shin-Hyung Lee, Won-Ja Kim, Jung-Yeon TI First characterization of Plasmodium vivax liver stage antigen (PvLSA) using synthetic peptides SO PARASITES & VECTORS LA English DT Article DE Plasmodium vivax; Liver stage antigen; Peptides ID CIRCUMSPOROZOITE PROTEIN; MALARIA VACCINE; T-CELLS; FALCIPARUM; RESPONSES; CHILDREN AB Background: Plasmodium vivax is the most widespread human malaria in tropical and subtropical countries, including the Republic of Korea. Vivax malaria is characterized by hypnozoite relapse and long latency infection by the retained liver stage of P. vivax, and somewhat surprisingly, little is known of the liver stage antigens of this parasite. Here, we report for the first time the characterization of a liver stage antigen of P. vivax (PvLSA). Methods: Five peptides located inside PvLSA were synthesized, and specific anti-sera to the respective peptides were used to localize PvLSA on P. vivax parasites in human liver cells by immunofluorescence. Western blotting and enzyme-linked immunosorbent assay were performed using the five peptides and sera collected from vivax malaria patients and from normal healthy controls. Results: PvLSA was localized on P. vivax parasites in human liver cells. Vivax malaria-infected patients were detected using the five peptides by western blotting. Furthermore, the peptides reacted with the sera of vivax malaria patients. Conclusions: These results suggest that PvLSA may function during the liver stage of P. vivax. C1 [Goo, Youn-Kyoung; Seo, Eun-Jeong; Choi, Yeon-Kyung; Shin, Hyun-Il; Ji, So-Young; Cho, Shin-Hyung; Lee, Won-Ja; Kim, Jung-Yeon] Korea CDC, Natl Inst Hlth, Div Malaria & Parasit Dis, Osong, South Korea. [Goo, Youn-Kyoung] Kyungpook Natl Univ, Sch Med, Dept Parasitol & Trop Med, Taegu 702701, South Korea. [Sattabongkot, Jetsumon] Armed Forces Res Inst Med Sci, Dept Entomol, Bangkok 10400, Thailand. [Chong, Chom-Kyu] Dankook Univ, GenBody Inc, Biotech Business IC, Cheonan, Chungnam, South Korea. RP Kim, JY (reprint author), Korea CDC, Natl Inst Hlth, Div Malaria & Parasit Dis, Osong Saeng Myeong 2 Ro, Osong, South Korea. EM jykim-malaria@nih.go.kr FU Korea National Institute of Health [2011-N54003-00] FX This study was supported by an intramural grant from the Korea National Institute of Health (#2011-N54003-00). NR 24 TC 4 Z9 4 U1 0 U2 1 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1756-3305 J9 PARASITE VECTOR JI Parasites Vectors PD FEB 12 PY 2014 VL 7 AR 64 DI 10.1186/1756-3305-7-64 PG 6 WC Parasitology SC Parasitology GA AF9WI UT WOS:000335065000001 PM 24520895 ER PT J AU Wright, JG Plikaytis, BD Rose, CE Parker, SD Babcock, J Keitel, W El Sahly, H Poland, GA Jacobson, RM Keyserling, HL Semenova, VA Li, H Schiffer, J Dababneh, H Martin, SK Martin, SW Marano, N Messonnier, NE Quinn, CP AF Wright, Jennifer G. Plikaytis, Brian D. Rose, Charles E. Parker, Scott D. Babcock, Janiine Keitel, Wendy El Sahly, Hana Poland, Gregory A. Jacobson, Robert M. Keyserling, Harry L. Semenova, Vera A. Li, Han Schiffer, Jarad Dababneh, Hanan Martin, Sandra K. Martin, Stacey W. Marano, Nina Messonnier, Nancy E. Quinn, Conrad P. TI Effect of reduced dose schedules and intramuscular injection of anthrax vaccine adsorbed on immunological response and safety profile: A randomized trial SO VACCINE LA English DT Article DE Anthrax vaccines; Bacillus anthracis; Bacterial vaccines; Vaccination; Adverse events ID LETHAL TOXIN NEUTRALIZATION; SIDED TESTS PROCEDURE; PROTECTIVE ANTIGEN; BACILLUS-ANTHRACIS; RHESUS MACAQUES; COMPARATIVE EFFICACY; INHALATION ANTHRAX; IMMUNOGLOBULIN-G; GUINEA-PIGS; IMMUNOGENICITY AB Objective: We evaluated an alternative administration route, reduced schedule priming series, and increased intervals between booster doses for anthrax vaccine adsorbed (AVA). AVA's originally licensed schedule was 6 subcutaneous (SQ) priming injections administered at months (m) 0, 0.5, 1, 6, 12 and 18 with annual boosters; a simpler schedule is desired. Methods: Through a multicenter randomized, double blind, non-inferiority Phase IV human clinical trial, the originally licensed schedule was compared to four alternative and two placebo schedules. 8-SQgroup participants received 6 SQ injections with m30 and m42 "annual" boosters; participants in the 8-IM group received intramuscular (IM) injections according to the same schedule. Reduced schedule groups (7-IM, 5-IM, 4-IM) received IM injections at m0, m1, m6; at least one of the m0.5, m12, m18, m30 vaccine doses were replaced with saline. All reduced schedule groups received a m42 booster. Post-injection blood draws were taken two to four weeks following injection. Non-inferiority of the alternative schedules was compared to the 8-SQ group at m2, m7, and m43. Reactogenicity outcomes were proportions of injection site and systemic adverse events (AEs). Results: The 8-IM group's m2 response was non-inferior to the 8-SQgroup for the three primary endpoints of anti-protective antigen IgG geometric mean concentration (GMC), geometric mean titer, and proportion of responders with a 4-fold rise in titer. At m7 anti-PA IgG GMCs for the three reduced dosage groups were non-inferior to the 8-SQ group GMCs. At m43, 8-IM, 5-IM, and 4-IM group GMCs were superior to the 8-SQ group. Solicited injection site AEs occurred at lower proportions in the IM group compared to SQ. Route of administration did not influence the occurrence of systemic AEs. A 3 dose IM priming schedule with doses administered at m0, m1, and m6 elicited long term immunological responses and robust immunological memory that was efficiently stimulated by a single booster vaccination at 42 months. Conclusions: A priming series of 3 intramuscular doses administered at m0, m1, and m6 with a triennial booster was non-inferior to more complex schedules for achieving antibody response. Published by Elsevier Ltd. C1 [Wright, Jennifer G.; Plikaytis, Brian D.; Rose, Charles E.; Semenova, Vera A.; Li, Han; Schiffer, Jarad; Dababneh, Hanan; Martin, Sandra K.; Martin, Stacey W.; Marano, Nina; Messonnier, Nancy E.; Quinn, Conrad P.] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA. [Parker, Scott D.] Univ Alabama Birmingham, Alabama Vaccine Res Clin, Birmingham, AL 35294 USA. [Babcock, Janiine] Walter Reed Army Inst Res, Silver Spring, MD 20910 USA. [Keitel, Wendy; El Sahly, Hana] Baylor Coll Med, Dept Mol Virol & Microbiol, Houston, TX 77030 USA. [Keitel, Wendy; El Sahly, Hana] Baylor Coll Med, Dept Med, Houston, TX 77030 USA. [Poland, Gregory A.; Jacobson, Robert M.] Mayo Clin & Mayo Fdn, Rochester, MN 55905 USA. [Keyserling, Harry L.] Emory Univ, Sch Med, Atlanta, GA 30322 USA. RP Wright, JG (reprint author), Natl Ctr Emerging Zoonot & Infect Dis, Div Foodborne Waterborne & Environm Dis, 1600 Clifton Rd NE,MS A-38, Atlanta, GA 30333 USA. EM jgwright@cdc.gov OI Babcock, Janiine/0000-0002-9007-880X; Jacobson, Robert/0000-0002-6355-8752 FU Centers for Disease Control and Prevention (CDC) FX The study was funded through the Centers for Disease Control and Prevention (CDC). NR 46 TC 20 Z9 20 U1 0 U2 7 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0264-410X EI 1873-2518 J9 VACCINE JI Vaccine PD FEB 12 PY 2014 VL 32 IS 8 BP 1019 EP 1028 DI 10.1016/j.vaccine.2013.10.039 PG 10 WC Immunology; Medicine, Research & Experimental SC Immunology; Research & Experimental Medicine GA AB0VM UT WOS:000331510200020 PM 24373307 ER PT J AU Tenhaeff, WE Rangasamy, E Wang, YY Sokolov, AP Wolfenstine, J Sakamoto, J Dudney, NJ AF Tenhaeff, Wyatt E. Rangasamy, Ezhiyl Wang, Yangyang Sokolov, Alexei P. Wolfenstine, Jeff Sakamoto, Jeffrey Dudney, Nancy J. TI Resolving the Grain Boundary and Lattice Impedance of Hot-Pressed Li7La3Zr2O12 Garnet Electrolytes SO CHEMELECTROCHEM LA English DT Article DE ceramics; energy storage; impedance spectroscopy; lithium; solid electrolyte ID SOLID-ELECTROLYTE C1 [Tenhaeff, Wyatt E.; Dudney, Nancy J.] Oak Ridge Natl Lab, Div Mat Sci & Technol, Oak Ridge, TN 37830 USA. [Rangasamy, Ezhiyl; Sakamoto, Jeffrey] Michigan State Univ, E Lansing, MI 48824 USA. [Wang, Yangyang; Sokolov, Alexei P.] Oak Ridge Natl Lab, Div Chem Sci, Oak Ridge, TN USA. [Sokolov, Alexei P.] Univ Tennessee, Dept Chem, Knoxville, TN 37996 USA. [Wolfenstine, Jeff] Army Res Lab, Adelphi, MD USA. RP Tenhaeff, WE (reprint author), Oak Ridge Natl Lab, Div Mat Sci & Technol, Oak Ridge, TN 37830 USA. EM wyatt.tenhaeff@rochester.edu RI Wang, Yangyang/A-5925-2010; Dudney, Nancy/I-6361-2016 OI Wang, Yangyang/0000-0001-7042-9804; Dudney, Nancy/0000-0001-7729-6178 FU Office of Vehicle Technologies of the U.S. Department of Energy [DE-AC02-05CH11231]; U. S. Army Research Office [W911NF0910451]; Army Research Lab FX This work was supported by the Assistant Secretary for Energy Efficiency and Renewable Energy, Office of Vehicle Technologies of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231. Y.Y.W. and A.P.S. acknowledge the Laboratory Directed Research and Development Program of Oak Ridge National Laboratory, managed by UT-Battelle, LLC, for the U.S. Department of Energy. Authors J.S. and E.L. acknowledge the support of the U. S. Army Research Office under contract/grant number W911NF0910451. J.W. would like to acknowledge support from the Army Research Lab. NR 12 TC 18 Z9 18 U1 12 U2 73 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY SN 2196-0216 J9 CHEMELECTROCHEM JI ChemElectroChem PD FEB 11 PY 2014 VL 1 IS 2 BP 375 EP 378 DI 10.1002/celc.201300022 PG 4 WC Electrochemistry SC Electrochemistry GA AK3AU UT WOS:000338295400013 ER PT J AU Haley, BJ Kokashvili, T Tskshvediani, A Janelidze, N Mitaishvili, N Grim, CJ de Magny, GC Chen, AJ Taviani, E Eliashvili, T Tediashvili, M Whitehouse, CA Colwell, RR Huq, A AF Haley, Bradd J. Kokashvili, Tamar Tskshvediani, Ana Janelidze, Nino Mitaishvili, Nino Grim, Christopher J. de Magny, Guillaume Constantin Chen, Arlene J. Taviani, Elisa Eliashvili, Tamar Tediashvili, Marina Whitehouse, Chris A. Colwell, Rita R. Huq, Anwar TI Molecular diversity and predictability of Vibrio parahaemolyticus along the Georgian coastal zone of the Black Sea SO FRONTIERS IN MICROBIOLOGY LA English DT Article DE Vibrio parahaemolyticus; predictive modeling; Vibrionaceae; Black Sea; aquatic microbiology ID PANDEMIC O3-K6 CLONE; CLINICAL STRAINS; GENETIC DIVERSITY; CHOLERAE; IDENTIFICATION; PCR; OUTBREAKS; THAILAND; NON-O1; WATERS AB Vibrio parahaemolyticus is a leading cause of seafood-related gastroenteritis and is also an autochthonous member of marine and estuarine environments worldwide. One-hundred seventy strains of V parahaemolyticus were isolated from water and plankton samples collected along the Georgian coast of the Black Sea during 28 months of sample collection. All isolated strains were tested for presence of tlh, trh, and tdh. A subset of strains were serotyped and tested for additional factors and markers of pandemicity. Twenty-six serotypes, five of which are clinically relevant, were identified. Although all 170 isolates were negative for tdh, trh, and the Kanagawa Phenomenon, 7 possessed the GS-PCR sequence and 27 the 850 bp sequence of V parahaemolyticus pandemic strains. The V parahaemolyticus population in the Black Sea was estimated to be genomically heterogeneous by rep-PCR and the serodiversity observed did not correlate with rep-PCR genomic diversity. Statistical modeling was used to predict presence of V parahaemolyticus as a function of water temperature, with strongest concordance observed for Green Cape site samples (Percent of total variance = 70, P < 0.001). Results demonstrate a diverse population of V parahaemolyticus in the Black Sea, some of which carry pandemic markers, with increased water temperature correlated to an increase in abundance of V parahaemolyticus. C1 [Haley, Bradd J.; Grim, Christopher J.; Chen, Arlene J.; Taviani, Elisa; Colwell, Rita R.; Huq, Anwar] Univ Maryland, Maryland Pathogen Res Inst, College Pk, MD 20742 USA. [Kokashvili, Tamar; Tskshvediani, Ana; Janelidze, Nino; Mitaishvili, Nino; Eliashvili, Tamar; Tediashvili, Marina] George Eliava Inst Bacteriophages Microbiol & Vir, Tbilisi, Rep of Georgia. [Grim, Christopher J.; Colwell, Rita R.] Univ Maryland, Inst Adv Comp Sci, College Pk, MD 20742 USA. [de Magny, Guillaume Constantin] IRD Montpellier, MIVEGEC UMR IRD CNRS UM1&2 5290, Montpellier, France. [Whitehouse, Chris A.] US Army Med Res Inst Infect Dis, Ft Detrick, MD USA. [Colwell, Rita R.] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Baltimore, MD USA. [Colwell, Rita R.] CosmosID, College Pk, MD USA. [Huq, Anwar] Univ Maryland, Maryland Inst Appl Environm Hlth, Sch Publ Hlth, College Pk, MD 20742 USA. RP Huq, A (reprint author), Univ Maryland, Maryland Pathogen Res Inst, 3102 Biosci Res Bldg, College Pk, MD 20742 USA. EM huq@umd.edu OI Colwell, Rita R./0000-0001-5432-1502 FU Biological Threat Reduction Program of the U.S. Defense Threat Reduction Agency (DTRA) through Bechtel National Inc. [GG-13]; IC Postdoctoral Research Fellowship (NGA) [HM15820612010]; NIH [2R01A1039129-11A2]; NSF [0813066] FX The research described in this report was made possible by financial support provided by the Biological Threat Reduction Program of the U.S. Defense Threat Reduction Agency (DTRA) (Project # GG-13) through Bechtel National Inc., sponsor account number 24914416HC4W00000006. Christopher J. Grim was supported by an IC Postdoctoral Research Fellowship (NGA Grant #HM15820612010). Partial funding for this study was provided by NIH Grant No. 2R01A1039129-11A2 and NSF Grant No. 0813066. Opinions, interpretations, conclusions, and recommendations are those of the authors and are not necessarily endorsed by the U.S. Army. NR 62 TC 12 Z9 12 U1 2 U2 17 PU FRONTIERS RESEARCH FOUNDATION PI LAUSANNE PA PO BOX 110, LAUSANNE, 1015, SWITZERLAND SN 1664-302X J9 FRONT MICROBIOL JI Front. Microbiol. PD FEB 10 PY 2014 VL 5 AR 45 DI 10.3389/fmicb.2014.00045 PG 9 WC Microbiology SC Microbiology GA AB4VX UT WOS:000331789100001 PM 24575085 ER PT J AU Langel, FD Chiang, CY Lane, D Kenny, T Ojeda, JF Zhong, Y Che, JW Zhou, YY Ribot, W Kota, KP Bavari, S Panchal, RG AF Langel, Felicia D. Chiang, Chih-Yuan Lane, Douglas Kenny, Tara Ojeda, Jenifer F. Zhong, Yang Che, Jianwei Zhou, Yingyao Ribot, Wilson Kota, Krishna P. Bavari, Sina Panchal, Rekha G. TI Alveolar Macrophages Infected with Ames or Sterne Strain of Bacillus anthracis Elicit Differential Molecular Expression Patterns SO PLOS ONE LA English DT Article ID NF-KAPPA-B; LETHAL FACTOR; REGULATORY FACTOR-3; GENE-EXPRESSION; KINASE-KINASE; TNF-ALPHA; IN-VIVO; ACTIVATION; INFLAMMATION; APOPTOSIS AB Alveolar macrophages (AMs) phagocytose Bacillus anthracis following inhalation and induce the production of proinflammatory cytokines and chemokines to mediate the activation of innate immunity. Ames, the virulent strain of B. anthracis, contains two plasmids that encode the antiphagocytic poly-gamma-d-glutamic acid capsule and the lethal toxin. The attenuated Sterne strain of B. anthracis, which lacks the plasmid encoding capsule, is widely adapted as a vaccine strain. Although differences in the outcome of infection with the two strains may have originated from the presence or absence of an anti-phagocytic capsule, the disease pathogenesis following infection will be manifested via the host responses, which is not well understood. To gain understanding of the host responses at cellular level, a microarray analysis was performed using primary rhesus macaque AMs infected with either Ames or Sterne spores. Notably, 528 human orthologs were identified to be differentially expressed in AMs infected with either strain of the B. anthracis. Meta-analyses revealed genes differentially expressed in response to B. anthracis infection were also induced upon infections with multiple pathogens such as Francisella Novicida or Staphylococcus aureus. This suggests the existence of a common molecular signature in response to pathogen infections. Importantly, the microarray and protein expression data for certain cytokines, chemokines and host factors provide further insights on how cellular processes such as innate immune sensing pathways, anti-apoptosis versus apoptosis may be differentially modulated in response to the virulent or vaccine strain of B. anthracis. The reported differences may account for the marked difference in pathogenicity between these two strains. C1 [Langel, Felicia D.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA. [Chiang, Chih-Yuan; Ojeda, Jenifer F.; Bavari, Sina; Panchal, Rekha G.] US Army Med Res Inst Infect Dis, Mol & Translat Sci Div, Ft Detrick, MD 21702 USA. [Lane, Douglas; Kenny, Tara] SAIC Frederick Inc, Frederick Natl Lab Canc Res, Frederick, MD USA. [Zhong, Yang; Che, Jianwei; Zhou, Yingyao] Novartis Res Fdn, Genom Inst, San Diego, CA USA. [Ribot, Wilson] US Army Med Res Inst Infect Dis, Bacteriol Div, Ft Detrick, MD USA. [Kota, Krishna P.] Perkin Elmer, Waltham, MA USA. RP Panchal, RG (reprint author), US Army Med Res Inst Infect Dis, Mol & Translat Sci Div, Ft Detrick, MD 21702 USA. EM rekha.g.panchal.civ@mail.mil FU Department of Defense Chemical Biological Defense Program through the Defense Threat Reduction Agency (DTRA) [JSTO-CBD 2.10019_09_RD_B]; National Cancer Institute, National Institutes of Health [HHSN261200800001E] FX This work was funded by the Department of Defense Chemical Biological Defense Program through the Defense Threat Reduction Agency (DTRA) JSTO-CBD 2.10019_09_RD_B (to R.G.P). This project has been funded in whole or in part with federal funds from the National Cancer Institute, National Institutes of Health, under Contract No. HHSN261200800001E. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. NR 34 TC 0 Z9 0 U1 1 U2 7 PU PUBLIC LIBRARY SCIENCE PI SAN FRANCISCO PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA SN 1932-6203 J9 PLOS ONE JI PLoS One PD FEB 7 PY 2014 VL 9 IS 2 AR e87201 DI 10.1371/journal.pone.0087201 PG 13 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA AA1CR UT WOS:000330834400011 PM 24516547 ER PT J AU Moore, CW Obrist, D Steffen, A Staebler, RM Douglas, TA Richter, A Nghiem, SV AF Moore, Christopher W. Obrist, Daniel Steffen, Alexandra Staebler, Ralf M. Douglas, Thomas A. Richter, Andreas Nghiem, Son V. TI Convective forcing of mercury and ozone in the Arctic boundary layer induced by leads in sea ice SO NATURE LA English DT Article ID ATMOSPHERIC MERCURY; GASEOUS MERCURY; ELEMENTAL MERCURY; HEAT-TRANSFER; DEPLETION; OCEAN; TROPOSPHERE; CANADA; WATERS; WINTER AB The ongoing regime shift of Arctic sea ice from perennial to seasonal ice is associated with more dynamic patterns of opening and closing sea-ice leads (large transient channels of open water in the ice)(1-3), which may affect atmospheric and biogeochemical cycles in the Arctic(4). Mercury and ozone are rapidly removed from the atmospheric boundary layer during depletion events in the Arctic(5-7), caused by destruction of ozone along with oxidation of gaseous elemental mercury (Hg(0)) to oxidized mercury (Hg(II)) in the atmosphere and its subsequent deposition to snow and ice(5). Ozone depletion events can change the oxidative capacity of the air by affecting atmospheric hydroxyl radical chemistry(8), whereas atmospheric mercury depletion events can increase the deposition of mercury to the Arctic(6,9-11), some of which can enter ecosystems during snowmelt(12). Here we present near-surface measurements of atmospheric mercury and ozone from two Arctic field campaigns near Barrow, Alaska. We find that coastal depletion events are directly linked to sea-ice dynamics. A consolidated ice cover facilitates the depletion of Hg(0) and ozone, but these immediately recover to near-background concentrations in the upwind presence of open sea-ice leads. We attribute the rapid recoveries of Hg(0) and ozone to lead-initiated shallow convection in the stable Arctic boundary layer, which mixes Hg(0) and ozone from undepleted air masses aloft. This convective forcing provides additional Hg(0) to the surface layer at a time of active depletion chemistry, where it is subject to renewed oxidation. Future work will need to establish the degree to which large-scale changes in sea-ice dynamics across the Arctic alter ozone chemistry and mercury deposition in fragile Arctic ecosystems. C1 [Moore, Christopher W.; Obrist, Daniel] Desert Res Inst, Div Atmospher Sci, Reno, NV 89523 USA. [Steffen, Alexandra; Staebler, Ralf M.] Environm Canada, Air Qual Proc Res Sect, Toronto, ON M3H 5T4, Canada. [Douglas, Thomas A.] US Army Cold Reg Res & Engn Lab, Ft Wainwright, AK 99703 USA. [Richter, Andreas] Univ Bremen, Inst Environm Phys, D-28359 Bremen, Germany. [Nghiem, Son V.] CALTECH, Jet Prop Lab, Pasadena, CA 91109 USA. RP Moore, CW (reprint author), Desert Res Inst, Div Atmospher Sci, Reno, NV 89523 USA. EM chris.moore@dri.edu RI Moore, Christopher/E-8448-2012; OI Moore, Christopher/0000-0002-6042-5583; Richter, Andreas/0000-0003-3339-212X FU National Aeronautics and Space Administration (NASA); Desert Research Institute; Science and Technology Branch of Environment Canada; Canadian International Polar Year government programme; NASA CSP FX This research was supported in part by the National Aeronautics and Space Administration (NASA) Cryospheric Sciences Program (CSP) and by the Desert Research Institute. The Science and Technology Branch of Environment Canada helped fund Hg measurements in 2012 along with the Canadian International Polar Year government programme in 2009. The research at the Jet Propulsion Laboratory, California Institute of Technology, was supported by NASA CSP. We thank Umiaq for field logistic assistance, the Barrow whaling community for beneficial interactions, and the National Oceanic and Atmosphere Administration (NOAA), Global Monitoring Division for the Barrow Observatory data. We gratefully acknowledge the NOAA Air Resources Laboratory (ARL) for provision of the HYSPLIT transport and dispersion model and READY Website (http://www.ready.noaa.gov) used in this publication. We thank K. Pratt and R. Kreidberg for feedback on the manuscript, B. Hatchett and T. Malamakal for help with radiosonde and WRF data, D. Hall and J. Schmaltz for MODIS imagery support, and J. Deary for outstanding field technical support. NR 32 TC 27 Z9 28 U1 8 U2 73 PU NATURE PUBLISHING GROUP PI LONDON PA MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND SN 0028-0836 EI 1476-4687 J9 NATURE JI Nature PD FEB 6 PY 2014 VL 506 IS 7486 BP 81 EP + DI 10.1038/nature12924 PG 11 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA 303BA UT WOS:000330648100035 PM 24429521 ER PT J AU Dow, GS McCarthy, WF Reid, M Smith, B Tang, D Shanks, GD AF Dow, Geoffrey S. McCarthy, William F. Reid, Mark Smith, Bryan Tang, Douglas Shanks, G. Dennis TI A retrospective analysis of the protective efficacy of tafenoquine and mefloquine as prophylactic anti-malarials in non-immune individuals during deployment to a malaria-endemic area SO MALARIA JOURNAL LA English DT Article ID PLASMODIUM-FALCIPARUM MALARIA; DOUBLE-BLIND; SOUTHWEST PACIFIC; EAST TIMOR; PRIMAQUINE; VIVAX; TOLERABILITY; REGIMENS; TRIAL AB Background: In 2000/2001, the Australian Defense Forces (ADF), in collaboration with SmithKline Beecham and the United States Army, conducted a field trial to evaluate the safety, tolerability and efficacy of tafenoquine and mefloquine/primaquine for the prophylaxis of malaria amongst non-immune Australian soldiers deployed to East Timor (now called Timor Leste) for peacekeeping operations. The lack of a concurrent placebo control arm prevented an internal estimate of the malaria attack rate and so the protective efficacy of the study regimens was not determined at the time. Methods: In a retrospective analysis of the trial results, the all species malaria attack rate was estimated for the prophylactic phase of the study which was defined as the period between administration of the first prophylactic dose and the first dose of post-deployment medication. First, the Plasmodium vivax attack rate was estimated during the prophylactic phase of the deployment by adjusting the observed P. vivax relapse rate during post-deployment to account for the known anti-relapse efficacies (or effectiveness) of the study medications (determined from prior studies). The all species malaria attack rate (P. vivax and Plasmodium falciparum) was then determined by adjusting the P. vivax attack rate based on the ratio of P. falciparum to P. vivax observed during prior ADF deployments to Timor Leste. This estimated all species malaria attack rate was then used as the `constant estimated attack rate' in the calculation of the protective efficacy of tafenoquine and mefloquine during the prophylactic phase of the deployment. Results: The estimated attack rate during the prophylactic phase of the study was determined to be 7.88%. The protective efficacies of tafenoquine and mefloquine, with corresponding 95% confidence intervals (95% CI), were determined to be 100% (93%-100%) and 100% (79%-100%) respectively. Conclusions: The protective efficacy of tafenoquine (200 mg per day for three days, followed by weekly 200 mg maintenance doses) is similar to that of the weekly standard of care (mefloquine, 250 mg). C1 [Dow, Geoffrey S.; McCarthy, William F.; Smith, Bryan; Tang, Douglas] US Army Med Mat Dev Act, Ft Detrick, MD 21702 USA. [Reid, Mark] Clin Network Serv, Toowong, Qld 4066, Australia. [Shanks, G. Dennis] Australian Army Malaria Inst, Enoggera, Qld 4051, Australia. RP Dow, GS (reprint author), US Army Med Mat Dev Act, 1430 Vet Dr, Ft Detrick, MD 21702 USA. EM geoffdow@hotmail.com RI Shanks, George Dennis/F-4056-2014 OI Shanks, George Dennis/0000-0001-5763-8660 NR 27 TC 9 Z9 9 U1 1 U2 8 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1475-2875 J9 MALARIA J JI Malar. J. PD FEB 6 PY 2014 VL 13 AR 13:49 DI 10.1186/1475-2875-13-49 PG 13 WC Infectious Diseases; Parasitology; Tropical Medicine SC Infectious Diseases; Parasitology; Tropical Medicine GA AC8GQ UT WOS:000332771900001 PM 24502679 ER PT J AU Lee, GH Cheng, YW Varanasi, CV Liu, J AF Lee, Gyeonghee Cheng, Yingwen Varanasi, Chakrapani V. Liu, Jie TI Influence of the Nickel Oxide Nanostructure Morphology on the Effectiveness of Reduced Graphene Oxide Coating in Supercapacitor Electrodes SO JOURNAL OF PHYSICAL CHEMISTRY C LA English DT Article ID ELECTROCHEMICAL ENERGY-STORAGE; NIO NANOPLATELET ARRAYS; CARBON NANOTUBES; PERFORMANCE; CAPACITORS; NANOSHEETS; TRANSITION; COMPOSITE; BEHAVIOR; DESIGN AB The effect of composition and microstructure of NiO on the electrochemical properties of NiO/reduced graphene oxide-based supercapacitor electrodes prepared by solvothermal methods were investigated systematically. The findings reveal that the influences of reduced graphene oxide (RGO) coating on electrode systems are essentially 2-fold. One is to increase the electrical conductivity of the electrodes, especially when the electrodes are not very conductive. However, this influence is not that obvious when the electrodes are already highly conductive to begin with. The second influence, is to improve the mechanical stability of the electrode, thus increasing the cyclability of the electrodes. Moreover, adding glucose during the electrode synthesis reduces the particle size as well as the thickness of deposited active material (NiO) on the substrate under similar mass loading. These thinner but denser NiO structures exhibited much improved electrochemical performance. These understandings will be important in the designing of high performance energy storage devices, especially from materials with limited electrical conductivity. C1 [Lee, Gyeonghee; Cheng, Yingwen; Liu, Jie] Duke Univ, Dept Chem, Durham, NC 27708 USA. [Varanasi, Chakrapani V.] Army Res Off, Durham, NC 27703 USA. RP Liu, J (reprint author), Duke Univ, Dept Chem, Durham, NC 27708 USA. EM j.liu@duke.edu RI Cheng, Yingwen/B-2202-2012; Liu, Jie/B-4440-2010 OI Cheng, Yingwen/0000-0002-0778-5504; Liu, Jie/0000-0003-0451-6111 FU Army Research Office (ARO) [W911NF-04-D-0001]; Duke SMIF FX This work is supported by a research grant from Army Research Office (ARO) under contract W911NF-04-D-0001. However, any opinions, findings, conclusions, or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the ARO. The authors also acknowledge the support from Duke SMIF (Shared Materials Instrumentation Facilities). NR 36 TC 27 Z9 27 U1 6 U2 123 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1932-7447 J9 J PHYS CHEM C JI J. Phys. Chem. C PD FEB 6 PY 2014 VL 118 IS 5 BP 2281 EP 2286 DI 10.1021/jp4094904 PG 6 WC Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Chemistry; Science & Technology - Other Topics; Materials Science GA AA5QC UT WOS:000331153700006 ER PT J AU Petrie, JR Urazhdin, S Wieland, KA Fischer, GA Edelstein, AS AF Petrie, J. R. Urazhdin, S. Wieland, K. A. Fischer, G. A. Edelstein, A. S. TI Using a spin torque nano-oscillator to read memory based on the magnetic permeability SO JOURNAL OF PHYSICS D-APPLIED PHYSICS LA English DT Article DE spin torque nano-oscillator; magnetic permeability; memory ID DRIVEN; MEDIA; NOISE AB We present an archival memory utilizing a spin torque nano-oscillator (STNO) to read bits of data with different magnetic permeability. Basing a magnetic memory on this intrinsic property rather than remanent magnetization reduces the risk of data corruption. The permeability of the bits is read as changes in an applied probe field near the media. These changes in the probe field are measured by detecting microwave frequency shifts in STNOs. The probe field can be tuned over hundreds of Oe to optimize the reading of the media. Using a 400 Oe probe field, we have measured 2% frequency shifts in a STNO near micrometre-sized bits of (1) lithographically-patterned permalloy lines and (2) laser-crystallized Metglas lines. Data from either media was not corrupted by exposure to fields of 6400 Oe and temperatures of 523 K. C1 [Petrie, J. R.; Wieland, K. A.; Fischer, G. A.; Edelstein, A. S.] US Army Res Lab, Adelphi, MD 20873 USA. [Urazhdin, S.] Emory Univ, Dept Phys, Atlanta, GA 30322 USA. RP Petrie, JR (reprint author), US Army Res Lab, Adelphi, MD 20873 USA. NR 29 TC 6 Z9 6 U1 1 U2 19 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 0022-3727 EI 1361-6463 J9 J PHYS D APPL PHYS JI J. Phys. D-Appl. Phys. PD FEB 5 PY 2014 VL 47 IS 5 AR 055002 DI 10.1088/0022-3727/47/5/055002 PG 7 WC Physics, Applied SC Physics GA 289ZB UT WOS:000329720200002 ER PT J AU Jackson, R Oda, RP Bhandari, RK Mahon, SB Brenner, M Rockwood, GA Logue, BA AF Jackson, Randy Oda, Robert P. Bhandari, Raj K. Mahon, Sari B. Brenner, Matthew Rockwood, Gary A. Logue, Brian A. TI Development of a Fluorescence-Based Sensor for Rapid Diagnosis of Cyanide Exposure SO ANALYTICAL CHEMISTRY LA English DT Article ID METABOLITE 2-AMINOTHIAZOLINE-4-CARBOXYLIC ACID; AQUEOUS ENVIRONMENT; MASS-SPECTROMETRY; BLOOD; PLASMA; URINE; THIOCYANATE; PROBE AB Although commonly known as a highly toxic chemical, cyanide is also an essential reagent for many industrial processes in areas such as mining, electroplating, and synthetic fiber production. The "heavy" use of cyanide in these industries, along with its necessary transportation, increases the possibility of human exposure. Because the onset of cyanide toxicity is fast, a rapid, sensitive, and accurate method for the diagnosis of cyanide exposure is necessary. Therefore, a field sensor for the diagnosis of cyanide exposure was developed based on the reaction of naphthalene dialdehyde, taurine, and cyanide, yielding a fluorescent beta-isoindole. An integrated cyanide capture "apparatus", consisting of sample and cyanide capture chambers, allowed rapid separation of cyanide from blood samples. Rabbit whole blood was added to the sample chamber, acidified, and the HCN gas evolved was actively transferred through a stainless steel channel to the capture chamber containing a basic solution of naphthalene dialdehyde (NDA) and taurine. The overall analysis time (including the addition of the sample) was <3 min, the linear range was 3.13-200 mu M, and the limit of detection was 0.78 mu M. None of the potential interferents investigated (NaHS, NH4OH, NaSCN, and human serum albumin) produced a signal that could be interpreted as a false positive or a false negative for cyanide exposure. Most importantly, the sensor was 100% accurate in diagnosing cyanide poisoning for acutely exposed rabbits. C1 [Jackson, Randy; Oda, Robert P.; Bhandari, Raj K.; Logue, Brian A.] S Dakota State Univ, Dept Chem & Biochem, Brookings, SD 57007 USA. [Mahon, Sari B.; Brenner, Matthew] Univ Calif Irvine, Beckman Laser Inst & Med Clin, Irvine, CA 92612 USA. [Brenner, Matthew] Univ Calif Irvine, Dept Med, Div Pulm & Crit Care Med, Irvine, CA 92868 USA. [Rockwood, Gary A.] US Army Med Res Inst Chem Def, Analyt Toxicol Div, Aberdeen Proving Ground, MD 21010 USA. RP Logue, BA (reprint author), S Dakota State Univ, Dept Chem & Biochem, Box 2202, Brookings, SD 57007 USA. EM brian.logue@sdstate.edu FU CounterACT Program, National Institutes of Health Office of the Director; National Institute of Allergy and Infectious Diseases [Y1-OD-0690-01/A-120-B.P2010-01, Y1-OD-1561-01/A120-B.P2011-01, AOD12060-001-00000/A120-B.P2012-01]; USAMRICD under U.S. Army Research Office of Scientific Services Program [W911NF-11-D-0001, TCN 11077]; Oak Ridge Institute for Science and Education (ORISE); National Science Foundation Major Research Instrumentation Program [CHE-0922816]; National Science Foundation/EPSCoR [0091948]; State of South Dakota FX The research was supported by the CounterACT Program, National Institutes of Health Office of the Director, and the National Institute of Allergy and Infectious Diseases, Interagency Agreement Numbers Y1-OD-0690-01/A-120-B.P2010-01, Y1-OD-1561-01/A120-B.P2011-01, AOD12060-001-00000/A120-B.P2012-01 and the USAMRICD under the auspices of the U.S. Army Research Office of Scientific Services Program Contract W911NF-11-D-0001 administered by Battelle (Delivery order 0079, Contract TCN 11077), USAMRMC W81XWH-12-2-0098, and NIH U54 NS079201. We gratefully acknowledge funding from the Oak Ridge Institute for Science and Education (ORISE). We thank the National Science Foundation Major Research Instrumentation Program (Grant CHE-0922816) for funding the AB SCIEX QTRAP 5500 LC-MS/MS. The LC-MS/MS instrumentation was housed in the South Dakota State University Campus Mass Spectrometry Facility, which was supported by the National Science Foundation/EPSCoR Grant 0091948 and the State of South Dakota. The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army, the National Institutes of Health, the National Science Foundation, or the Department of Defense. The authors declare that there are no conflicts of interest. The authors alone are responsible for the content and writing of the paper. NR 49 TC 28 Z9 28 U1 10 U2 62 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0003-2700 EI 1520-6882 J9 ANAL CHEM JI Anal. Chem. PD FEB 4 PY 2014 VL 86 IS 3 BP 1845 EP 1852 DI 10.1021/ac403846s PG 8 WC Chemistry, Analytical SC Chemistry GA AA3TI UT WOS:000331014800073 PM 24383576 ER PT J AU Zolla-Pazner, S deCamp, A Gilbert, PB Williams, C Yates, NL Williams, WT Howington, R Fong, YY Morris, DE Soderberg, KA Irene, C Reichman, C Pinter, A Parks, R Pitisuttithum, P Kaewkungwal, J Rerks-Ngarm, S Nitayaphan, S Andrews, C O'Connell, RJ Yang, ZY Nabel, GJ Kim, JH Michael, NL Montefiori, DC Liao, HX Haynes, BF Tomaras, GD AF Zolla-Pazner, Susan deCamp, Allan Gilbert, Peter B. Williams, Constance Yates, Nicole L. Williams, William T. Howington, Robert Fong, Youyi Morris, Daryl E. Soderberg, Kelly A. Irene, Carmela Reichman, Charles Pinter, Abraham Parks, Robert Pitisuttithum, Punnee Kaewkungwal, Jaranit Rerks-Ngarm, Supachai Nitayaphan, Sorachai Andrews, Charla O'Connell, Robert J. Yang, Zhi-yong Nabel, Gary J. Kim, Jerome H. Michael, Nelson L. Montefiori, David C. Liao, Hua-Xin Haynes, Barton F. Tomaras, Georgia D. TI Vaccine-Induced IgG Antibodies to V1V2 Regions of Multiple HIV-1 Subtypes Correlate with Decreased Risk of HIV-1 Infection SO PLOS ONE LA English DT Article ID HUMAN-IMMUNODEFICIENCY-VIRUS; HUMAN MONOCLONAL-ANTIBODIES; B-CELL RESPONSES; HIV-1-INFECTED INDIVIDUALS; CROSS-REACTIVITY; V1/V2 DOMAIN; ENVELOPE; NEUTRALIZATION; GP120; SEQUENCE AB In the RV144 HIV-1 vaccine efficacy trial, IgG antibody (Ab) binding levels to variable regions 1 and 2 (V1V2) of the HIV-1 envelope glycoprotein gp120 were an inverse correlate of risk of HIV-1 infection. To determine if V1V2-specific Abs cross-react with V1V2 from different HIV-1 subtypes, if the nature of the V1V2 antigen used to asses cross-reactivity influenced infection risk, and to identify immune assays for upcoming HIV-1 vaccine efficacy trials, new V1V2-scaffold antigens were designed and tested. Protein scaffold antigens carrying the V1V2 regions from HIV-1 subtypes A, B, C, D or CRF01_AE were assayed in pilot studies, and six were selected to assess cross-reactive Abs in the plasma from the original RV144 case-control cohort (41 infected vaccinees, 205 frequency-matched uninfected vaccinees, and 40 placebo recipients) using ELISA and a binding Ab multiplex assay. IgG levels to these antigens were assessed as correlates of risk in vaccine recipients using weighted logistic regression models. Levels of Abs reactive with subtype A, B, C and CRF01_AE V1V2-scaffold antigens were all significant inverse correlates of risk (p-values of 0.0008-0.05; estimated odds ratios of 0.53-0.68 per 1 standard deviation increase). Thus, levels of vaccine-induced IgG Abs recognizing V1V2 regions from multiple HIV-1 subtypes, and presented on different scaffolds, constitute inverse correlates of risk for HIV-1 infection in the RV144 vaccine trial. The V1V2 antigens provide a link between RV144 and upcoming HIV-1 vaccine trials, and identify reagents and methods for evaluating V1V2 Abs as possible correlates of protection against HIV-1 infection. C1 [Zolla-Pazner, Susan] New York Harbor Healthcare Syst, Dept Vet Affairs, New York, NY 10010 USA. [Zolla-Pazner, Susan; Williams, Constance] NYU, Sch Med, New York, NY USA. [deCamp, Allan; Gilbert, Peter B.; Fong, Youyi; Morris, Daryl E.] Fred Hutchinson Canc Res Ctr, Vaccine & Infect Dis Div, Seattle, WA 98104 USA. [Yates, Nicole L.; Williams, William T.; Howington, Robert; Soderberg, Kelly A.; Parks, Robert; Montefiori, David C.; Liao, Hua-Xin; Haynes, Barton F.; Tomaras, Georgia D.] Duke Univ, Durham, NC USA. [Irene, Carmela; Reichman, Charles; Pinter, Abraham] Univ Med & Dent New Jersey, Publ Hlth Res Inst, Newark, NJ 07103 USA. [Pitisuttithum, Punnee; Kaewkungwal, Jaranit] Fac Trop Med, Mahidol, Thailand. [Rerks-Ngarm, Supachai] Minist Publ Hlth, Bangkok, Thailand. [Nitayaphan, Sorachai] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand. [Andrews, Charla; O'Connell, Robert J.; Kim, Jerome H.; Michael, Nelson L.] Walter Reed Army Inst Res, Mil HIV Res Program, Silver Spring, MD USA. [Yang, Zhi-yong; Nabel, Gary J.] NIAID, Virol Lab, Vaccine Res Ctr, NIH, Bethesda, MD 20892 USA. RP Zolla-Pazner, S (reprint author), New York Harbor Healthcare Syst, Dept Vet Affairs, New York, NY 10010 USA. EM zollas01@med.nyu.edu RI Tomaras, Georgia/J-5041-2016 FU National Institutes of Health [P01 AI100151, R01 HL59725, P01 AI64518]; Bill and Melinda Gates Foundation [1040758, 3830913]; Military HIV Research Program; Department of Veterans Affairs, Veterans Health Administration, Office of Research and Development; U.S. Army Medical Research and Material Command (USAMRMC) [Y1-AI-2642-12]; National Institutes of Allergy and Infectious Diseases [Y1-AI-2642-12]; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. [W81XWH-07-2-0067]; U.S. Department of Defense [W81XWH-07-2-0067] FX Supported in part by grant funds from the National Institutes of Health: P01 AI100151 (SZP), R01 HL59725 (SZP), P01 AI64518 (Duke Center for AIDS Research); from the Bill and Melinda Gates Foundation: 1040758 (BFH), and 3830913 (DCM); from the Military HIV Research Program, and research funds from the Department of Veterans Affairs, Veterans Health Administration, Office of Research and Development. The work was also supported in part by an Interagency Agreement Y1-AI-2642-12 between the U.S. Army Medical Research and Material Command (USAMRMC) and the National Institutes of Allergy and Infectious Diseases and by a cooperative agreement (W81XWH-07-2-0067) between the Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., and the U.S. Department of Defense. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. NR 31 TC 83 Z9 84 U1 2 U2 16 PU PUBLIC LIBRARY SCIENCE PI SAN FRANCISCO PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA SN 1932-6203 J9 PLOS ONE JI PLoS One PD FEB 4 PY 2014 VL 9 IS 2 AR e87572 DI 10.1371/journal.pone.0087572 PG 14 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA 302VA UT WOS:000330631800045 PM 24504509 ER PT J AU Dong, L Dongare, AM Namburu, RR O'Regan, TP Dubey, M AF Dong, Liang Dongare, Avinash M. Namburu, Raju R. O'Regan, Terrance P. Dubey, Madan TI Theoretical study on strain induced variations in electronic properties of 2H-MoS2 bilayer sheets SO APPLIED PHYSICS LETTERS LA English DT Article ID DENSITY-FUNCTIONAL THEORY; MOS2 TRANSISTORS; LAYER; NANORIBBONS; MONOLAYER; CHEMISTRY; SUBSTRATE; CRYSTALS; GROWTH AB The strain dependence of the electronic properties of bilayer sheets of 2H-MoS2 is studied using ab initio simulations based on density functional theory. An indirect band gap for bilayer MoS2 is observed for all variations of strain along the basal plane. Several transitions for the indirect band gap are observed for various strains for the bilayer structure. The variation of the band gap and the carrier effective masses for the holes and the electrons for the bilayer MoS2 structure under conditions of uniaxial strain, biaxial strain, as well as uniaxial stress is investigated. (C) 2014 AIP Publishing LLC. C1 [Dong, Liang; Dongare, Avinash M.] Univ Connecticut, Dept Mat Sci & Engn, Storrs, CT 06269 USA. [Dong, Liang; Dongare, Avinash M.] Univ Connecticut, Inst Mat Sci, Storrs, CT 06269 USA. [Namburu, Raju R.] US Army Res Lab, Computat & Informat Sci Directorate, Aberdeen Proving Ground, MD 21005 USA. [O'Regan, Terrance P.; Dubey, Madan] US Army Res Lab, Sensors & Elect Devices Directorate, Adelphi, MD 20783 USA. RP Dongare, AM (reprint author), Univ Connecticut, Dept Mat Sci & Engn, Storrs, CT 06269 USA. EM dongare@uconn.edu RI Dong, Liang/O-3439-2015; OI Dongare, Avinash/0000-0003-3189-3588 FU U.S. Army Research Laboratory (ARL) Director's Strategic Initiative (DSI) FX This research was supported in part by an appointment of A. M. Dongare to the Faculty Research Participation Program at the U. S. Army Research Laboratory (USARL) administered by the Oak Ridge Institute for Science and Education through an interagency between the U. S. Department of Energy and ASARL. The authors R. R. Namburu, T. P. O'Regan, and M. Dubey acknowledge the support of the U.S. Army Research Laboratory (ARL) Director's Strategic Initiative (DSI) program on interfaces in stacked 2D atomic layered materials. NR 44 TC 11 Z9 11 U1 3 U2 72 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0003-6951 EI 1077-3118 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD FEB 3 PY 2014 VL 104 IS 5 AR 053107 DI 10.1063/1.4863827 PG 5 WC Physics, Applied SC Physics GA AB2TD UT WOS:000331644100108 ER PT J AU Eskreis-Winkler, L Shulman, EP Beal, SA Duckworth, AL AF Eskreis-Winkler, Lauren Shulman, Elizabeth P. Beal, Scott A. Duckworth, Angela L. TI The grit effect: predicting retention in the military, the workplace, school and marriage SO FRONTIERS IN PSYCHOLOGY LA English DT Article DE grit; conscientiousness; personality; retention; dropout ID 5 PERSONALITY DIMENSIONS; EMPLOYEE TURNOVER; ACADEMIC-ACHIEVEMENT; EFFORTFUL CONTROL; PHYSICAL-FITNESS; UNITED-STATES; DROPOUT; DIVORCE; MODEL; METAANALYSIS AB Remaining committed to goals is necessary (albeit not sufficient) to attaining them, but very little is known about domain-general individual differences that contribute to sustained goal commitment. The current investigation examines the association between grit, defined as passion and perseverance for long-term goals, other individual difference variables, and retention in four different contexts: the military, workplace sales, high school, and marriage. Grit predicted retention over and beyond established context-specific predictors of retention (e.g., intelligence, physical aptitude, Big Five personality traits, job tenure) and demographic variables in each setting. Grittier soldiers were more likely to complete an Army Special Operations Forces (ARSOF) selection course, grittier sales employees were more likely to keep their jobs, grittier students were more likely to graduate from high school, and grittier men were more likely to stay married. The relative predictive validity of grit compared to other traditional predictors of retention is examined in each of the four studies. These findings suggest that in addition to domain-specific influences, there may be domain-general individual differences which influence commitment to diverse life goals over time. C1 [Eskreis-Winkler, Lauren; Shulman, Elizabeth P.; Duckworth, Angela L.] Univ Penn, Dept Psychol, Philadelphia, PA 19104 USA. [Beal, Scott A.] US Army, Ft Bragg Res Element, Res Inst, Ft Belvoir, VA USA. RP Eskreis-Winkler, L (reprint author), Univ Penn, Dept Psychol, 3701 Market St,Suite 207, Philadelphia, PA 19104 USA. EM eskreisl@sas.upenn.edu NR 64 TC 20 Z9 20 U1 13 U2 92 PU FRONTIERS RESEARCH FOUNDATION PI LAUSANNE PA PO BOX 110, LAUSANNE, 1015, SWITZERLAND SN 1664-1078 J9 FRONT PSYCHOL JI Front. Psychol. PD FEB 3 PY 2014 VL 5 AR 36 DI 10.3389/fpsyg.2014.00036 PG 12 WC Psychology, Multidisciplinary SC Psychology GA AA7LB UT WOS:000331277800001 PM 24550863 ER PT J AU Adduci, LL McLaughlin, MP Bender, TA Becker, JJ Gagne, MR AF Adduci, Laura L. McLaughlin, Matthew P. Bender, Trandon A. Becker, Jennifer J. Gagne, Michel R. TI Metal-Free Deoxygenation of Carbohydrates SO ANGEWANDTE CHEMIE-INTERNATIONAL EDITION LA English DT Article DE biomass; carbohydrates; deoxygenation; hydrosilylation; renewable feedstocks ID IRIDIUM PINCER COMPLEXES; O BOND-CLEAVAGE; CATALYTIC CONVERSION; ALKYL ETHERS; BIOMASS; REDUCTION; ALCOHOLS; ALKANES; HYDRODEOXYGENATION; DEPOLYMERIZATION AB The conversion of readily available cellulosic biomass to valuable feedstocks and fuels is an attrative goal but a challenging transformation that requires the cleavage of multiple nonactivated CO bonds. Herein, the Lewis acid trispentafluorophenylborane (B(C6F5)(3)) is shown to catalyze the metal-free hydrosilylative reduction of monosaccharides and polysaccharides to give hydrocarbons with reduced oxygen content. The choice of the silane reductant influences the degree of deoxygenation, with diethylsilane effecting the complete reduction to produce hexanes while tertiary silanes give partially deoxygenated tetraol and triol products. C1 [Adduci, Laura L.; McLaughlin, Matthew P.; Bender, Trandon A.; Gagne, Michel R.] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA. [Becker, Jennifer J.] US Army, Res Off, Res Triangle Pk, NC 27709 USA. RP Gagne, MR (reprint author), Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA. EM mgagne@unc.edu FU National Research Council; Progress Energy Foundation/UNC Institute for the Environment; Department of Energy [DE-FG02-05ER15630]; Army Research Office FX M.P.M. thanks the National Research Council for a postdoctoral fellowship, L. L. A. thanks the Progress Energy Foundation/UNC Institute for the Environment, M. R. G. thanks the Department of Energy (DE-FG02-05ER15630),and J.J.B. thanks the Army Research Office for funding. NR 40 TC 28 Z9 28 U1 12 U2 145 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY SN 1433-7851 EI 1521-3773 J9 ANGEW CHEM INT EDIT JI Angew. Chem.-Int. Edit. PD FEB 3 PY 2014 VL 53 IS 6 BP 1646 EP 1649 DI 10.1002/anie.201306864 PG 4 WC Chemistry, Multidisciplinary SC Chemistry GA 301UU UT WOS:000330558400034 PM 24492972 ER PT J AU Chu, ML Guzman, JA Munoz-Carpena, R Riker, GA Linkov, I AF Chu, M. L. Guzman, J. A. Munoz-Carpena, R. Riker, G. A. Linkov, I. TI A simplified approach for simulating changes in beach habitat due to the combined effects of long-term sea level rise, storm erosion, and nourishment SO ENVIRONMENTAL MODELLING & SOFTWARE LA English DT Article DE SLAMM; Coastal erosion; Beach nourishment; Hurricanes; Risk contours ID DUNE EROSION; IMPACTS; FLORIDA; ACCRETION; ISLAND; RATES; COAST AB Better understanding of the vulnerability of coastal habitats to sea level rise and major storm events are aided by the use of simulation models. Since coastal habitats also undergo frequent nourishment restoration works in order to maintain their viability, vulnerability models must be able to assess the combined effects of sea level rise, storm surge, and beach nourishment. The Sea Level Affecting Marshes Model (SLAMM) was modified and applied to quantify the changes in the beach area in a 5-km stretch of beach in Santa Rosa Island, Florida due to these combined effects. A new methodology to estimate spatial erosion patterns was developed based on measured erosion during three historic storm events representing a wide range of storm intensities over the study area (named storms Ivan (H5), Dennis (H4), and Katrina (TS)). Future major storms over the 2012-2100 period were generated based on the frequency distribution of historic storms using 4000 simulations to account for uncertainty in the storms temporal distribution. Potential effects of individual, successive, and random storms occurring over the area under 0-1.5 m nourishment schemes were evaluated. The risk of losing the beach habitat in 90 years for different scenarios is studied based on probability distribution contours constructed with the model results. Simulation results suggest that without nourishment, a major storm with a category of tropical storm or higher will reduce the beach at the end of the period by 97-100%. This loss can be reduced to 60% by maintaining a 1-m beach elevation and can further be reduced to 34% with 1.5 m beach nourishment. (C) 2013 Elsevier Ltd. All rights reserved. C1 [Chu, M. L.; Munoz-Carpena, R.; Riker, G. A.] Univ Florida, Agr & Biol Engn Dept, Gainesville, FL 32611 USA. [Guzman, J. A.] USDA ARS, Grazinglands Res Lab, El Reno, OK 73036 USA. [Linkov, I.] US Army, Engn Res & Dev Ctr, Concord, MA 01366 USA. [Riker, G. A.] Univ KwaZulu Natal, SMCS, Durban, South Africa. RP Munoz-Carpena, R (reprint author), Univ Florida, Agr & Biol Engn Dept, POB 110570, Gainesville, FL 32611 USA. EM carpena@ufl.edu OI GUZMAN, Jorge A/0000-0002-7734-5723; Munoz-Carpena, Rafael/0000-0003-2838-1514 FU Department of Defense Strategic Environmental Research and Development Program [SI-1699]; UF Research Foundation Professorship; UF Water Institute Faculty Fellowship; University of Florida, High-Performance Computing Center FX Funding was provided by the Department of Defense Strategic Environmental Research and Development Program (project SI-1699). Permission was granted by the USACE Chief of Engineers to publish this material. The views and opinions expressed in this paper are those of the individual authors and not those of the U.S. Army, or other sponsor organizations. The authors acknowledge the University of Florida, High-Performance Computing Center (http://hpc.ufl.edu) for providing computational resources and support that have contributed to the results reported in this paper. Dr. Carpena acknowledges support from the UF Research Foundation Professorship and the UF Water Institute Faculty Fellowship. NR 37 TC 1 Z9 1 U1 8 U2 26 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 1364-8152 EI 1873-6726 J9 ENVIRON MODELL SOFTW JI Environ. Modell. Softw. PD FEB PY 2014 VL 52 BP 111 EP 120 DI 10.1016/j.envsoft.2013.10.020 PG 10 WC Computer Science, Interdisciplinary Applications; Engineering, Environmental; Environmental Sciences SC Computer Science; Engineering; Environmental Sciences & Ecology GA AX2CY UT WOS:000346751700010 ER PT J AU Roy, TC Fish, KL Lopez, HP Piva, SR AF Roy, Tanja C. Fish, Karen L. Lopez, Heather P. Piva, Sara R. TI Preliminary Validation of the Military Low Back Pain Questionnaire SO MILITARY MEDICINE LA English DT Article ID OSWESTRY DISABILITY INDEX; OPERATIONS IRAQI FREEDOM; BRIGADE COMBAT TEAM; PHYSICAL THERAPIST; ENDURING FREEDOM; AFGHANISTAN; INJURIES; SOLDIERS AB Soldiers must perform a variety of physical tasks that the civilian population does not. The Modified Oswestry Disability Index (M-ODI) is the most widely used measure of function in patients with low back pain but does not include military tasks. The Military Low Back Pain Questionnaire (MBQ) was developed by military Physical Therapists to include tasks such as wearing body armor. The purpose of this study was to provide preliminary evidence for the reliability, responsiveness, and validity of the MBQ in nondeployed Soldiers. The MBQ had good reliability compared to the M-ODI. The inter-rater correlation coefficient for the M-ODI was 0.79 and 0.75 for the MBQ. Cronbach's alpha was 0.75 and 0.85 for the M-ODI and MBQ, respectively. The minimal detectable change for the M-ODI was 21.03 and 22.97 for the MBQ. Responsiveness was assessed using a global rating of change; area under the curve for the M-ODI was 0.82 and 0.90 for the MBQ. The correlation between the M-ODI and the MBQ was r = 0.80 indicating good concurrent validity. The MBQ was as reliable as the M-ODI in an Army population. There were trends in the psychometrics suggesting the MBQ may be more sensitive to change than the M-ODI in this population. C1 [Roy, Tanja C.] US Army, Environm Med Res Inst, Natick, MA 01760 USA. [Fish, Karen L.] Ft Drum Med Dept Act, Ft Drum, NY 13602 USA. [Lopez, Heather P.] 101st Airborne Div, Brigade Combat Team 2, Ft Campbell, KY 42223 USA. [Piva, Sara R.] Univ Pittsburgh, Sch Hlth & Rehabil Sci, Phys Therapy Dept, Pittsburgh, PA 15260 USA. RP Roy, TC (reprint author), US Army, Environm Med Res Inst, 15 Kansas St, Natick, MA 01760 USA. FU U.S. Army Research Institute of Environmental Medicine under Task Area A FX This study was funded by the U.S. Army Research Institute of Environmental Medicine under Task Area A. NR 26 TC 0 Z9 0 U1 2 U2 5 PU ASSOC MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA SN 0026-4075 EI 1930-613X J9 MIL MED JI Milit. Med. PD FEB PY 2014 VL 179 IS 2 BP 121 EP 125 DI 10.7205/MILMED-D-13-00341 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA AN7UI UT WOS:000340806100002 PM 24491605 ER PT J AU Ross, MD Childs, JD Middel, C Kujawa, J Brown, D Corrigan, M Parsons, N AF Ross, Michael D. Childs, John D. Middel, Cory Kujawa, Julie Brown, Daniel Corrigan, Molly Parsons, Nate TI Physical Therapist vs. Family Practitioner Knowledge of Simple Low Back Pain Management in the US Air Force SO MILITARY MEDICINE LA English DT Article ID MANAGING-MUSCULOSKELETAL-CONDITIONS; CLINICAL-PREDICTION RULE; SPINAL MANIPULATION; PRIMARY-CARE; COHORT; DISORDERS; EPISODES; COST AB The purpose of this study was to compare knowledge in managing low back pain (LBP) between physical therapists and family practice physicians. Fifty-four physical therapists and 130 family practice physicians currently serving in the U.S. Air Force completed standardized examinations assessing knowledge, attitudes, the usefulness of clinical practice guidelines, and management strategies for patients with LBP. Beliefs of physical therapists and family practice physicians about LBP were compared using relative risks and independent t tests. Scores related to knowledge, attitudes, and the usefulness of clinical practice guidelines were generally similar between the groups. However, physical therapists were more likely to recommend the correct drug treatments for patients with acute LBP compared to family practice physicians (85.2% vs. 68.5%; relative risk: 1.24 [95% confidence interval: 1.06-1.46]) and believe that patient encouragement and explanation is important (75.9% vs. 56.2%; relative risk: 1.35 [95% confidence interval: 1.09-1.67]). In addition, physical therapists showed significantly greater knowledge regarding optimal management strategies for patients with LBP compared to family practice physicians. The results of this study may have implications for health policy decisions regarding the utilization of physical therapists to provide care for patients with LBP without a referral. C1 [Ross, Michael D.] Univ Scranton, Dept Phys Therapy, Scranton, PA 18510 USA. [Childs, John D.; Middel, Cory; Kujawa, Julie; Brown, Daniel; Corrigan, Molly; Parsons, Nate] US Army, Baylor Univ, ATTN MCCS HMT, Doctoral Program Phys Therapy, Ft Sam Houston, TX 78234 USA. RP Ross, MD (reprint author), Univ Scranton, Dept Phys Therapy, 800 Linden St, Scranton, PA 18510 USA. NR 31 TC 0 Z9 0 U1 0 U2 1 PU ASSOC MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA SN 0026-4075 EI 1930-613X J9 MIL MED JI Milit. Med. PD FEB PY 2014 VL 179 IS 2 BP 162 EP 168 DI 10.7205/MILMED-D-13-00099 PG 7 WC Medicine, General & Internal SC General & Internal Medicine GA AN7UI UT WOS:000340806100009 PM 24491612 ER PT J AU Bastian, ND Fulton, LV AF Bastian, Nathaniel D. Fulton, Lawrence V. TI Aeromedical Evacuation Planning Using Geospatial Decision-Support SO MILITARY MEDICINE LA English DT Article AB In this study, we proffer an algorithmic, geospatial-based decision-support methodology that assists military decision-makers in determining which aeromedical evacuation (MEDEVAC) assets to launch after receiving an injury location, given knowledge only of terrain, aircraft location, and aircraft capabilities. The objective is for military medical planners to use this decision-support tool (1) to improve real-time situational awareness by visualization of MEDEVAC coverage, showing which areas can be reached within established timelines; (2) to support medical planning by visualizing the impact of changes in the medical footprint to the MEDEVAC coverage; and (3) to support decision-making by providing a time-sorted list of MEDEVAC asset packages to select from, given the location of the patients. This same geospatial-based decision tool can be used for proper emplacement of evacuation assets such that the theater is covered within a truly representative 1-hour response time. We conclude with a discussion of applicability of this tool in medical force structure planning. C1 [Bastian, Nathaniel D.] Penn State Univ, Ctr Integrated Healthcare Delivery Syst, Dept Ind & Mfg Engn, University Pk, PA 16802 USA. [Bastian, Nathaniel D.] US Army, Med Dept Ctr & Sch, Med Capabil Integrat Ctr, Ctr AMEDD Strateg Studies, Ft Sam Houston, TX 78234 USA. [Bastian, Nathaniel D.] Baylor Univ, US Army, Grad Program Hlth & Business Adm, Med Dept Ctr & Sch, Ft Sam Houston, TX 78234 USA. [Fulton, Lawrence V.] Texas State Univ, McCoy Coll Business Adm, Dept Comp Informat Syst & Quantitat Methods, San Marcos, TX 78666 USA. RP Bastian, ND (reprint author), Penn State Univ, Ctr Integrated Healthcare Delivery Syst, Dept Ind & Mfg Engn, 355 Leonhard Bldg, University Pk, PA 16802 USA. FU National Science Foundation [DGE1255832] FX This material is based on work supported by the National Science Foundation under Grant no. DGE1255832. NR 8 TC 2 Z9 2 U1 1 U2 5 PU ASSOC MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA SN 0026-4075 EI 1930-613X J9 MIL MED JI Milit. Med. PD FEB PY 2014 VL 179 IS 2 BP 174 EP 182 DI 10.7205/MILMED-D-13-00432 PG 9 WC Medicine, General & Internal SC General & Internal Medicine GA AN7UI UT WOS:000340806100011 PM 24491614 ER PT J AU Bookstaver, DA Bland, CM Woodberry, MW Mansell, KB AF Bookstaver, David A. Bland, Christopher M. Woodberry, Mitchell W. Mansell, Karon B. TI Correlation of cefpodoxime susceptibility with cephalothin and cefuroxime for urinary tract isolates SO JOURNAL OF MEDICAL MICROBIOLOGY LA English DT Article ID ACUTE UNCOMPLICATED CYSTITIS; ESCHERICHIA-COLI; TRIMETHOPRIM-SULFAMETHOXAZOLE; RESISTANCE; WOMEN AB This study attempted to determine whether cefuroxime was superior to cephalothin as a surrogate marker for cefpodoxime among urinary tract isolates. The Micro Scan system (Siemens) was used to determine susceptibility for cephalothin and cefuroxime on consecutive cultures with a colony count of >= 50 000 organisms. Simultaneously, an Etest (bioMerieux) for cefpodoxime was conducted. The cefpodoxime interpretation was compared to that of the other two agents, and the categorical agreement was calculated, defined as the percentage of identical susceptibility interpretations. Cefuroxime (83%) had a significantly higher categorical agreement than cephalothin (63 %) among 300 isolates (P<0.01). The major error rate was 16% for cephalothin and 3% for cefuroxime. The very major error rate was 7% for cephalothin and 14 % for cefuroxime among the 14 cefpodoxime-resistant isolates. For Escherichia coli, the major error rates were 15% and 1 % for cephalothin and cefuroxime, respectively. Very major error rates were 9% for both agents. Cefuroxime was a better predictor of cefpodoxime susceptibility than cephalothin, and appears to be the preferred surrogate agent for the Micro Scan system, particularly for E. coli. C1 [Bookstaver, David A.; Bland, Christopher M.] Eisenhower Army Med Ctr, Dept Pharm, Ft Gordon, GA 30905 USA. [Woodberry, Mitchell W.; Mansell, Karon B.] Eisenhower Army Med Ctr, Dept Pathol, Ft Gordon, GA USA. RP Bookstaver, DA (reprint author), Eisenhower Army Med Ctr, Dept Pharm, Ft Gordon, GA 30905 USA. EM david.a.bookstaver.civ@mail.mil NR 11 TC 2 Z9 2 U1 0 U2 0 PU SOC GENERAL MICROBIOLOGY PI READING PA MARLBOROUGH HOUSE, BASINGSTOKE RD, SPENCERS WOODS, READING RG7 1AG, BERKS, ENGLAND SN 0022-2615 EI 1473-5644 J9 J MED MICROBIOL JI J. Med. Microbiol. PD FEB PY 2014 VL 63 BP 218 EP 221 DI 10.1099/jmm.0.063040-0 PN 2 PG 4 WC Microbiology SC Microbiology GA AK5PM UT WOS:000338478200008 PM 24214230 ER PT J AU Palacios, G Tesh, RB Savji, N da Rosa, APAT Guzman, H Bussetti, AV Desai, A Ladner, J Sanchez-Seco, M Lipkin, WI AF Palacios, Gustavo Tesh, Robert B. Savji, Nazir da Rosa, Amelia P. A. Travassos Guzman, Hilda Bussetti, Ana Valeria Desai, Aaloki Ladner, Jason Sanchez-Seco, Maripaz Lipkin, W. Ian TI Characterization of the Sandfly fever Naples species complex and description of a new Karimabad species complex (genus Phlebovirus, family Bunyaviridae) SO JOURNAL OF GENERAL VIROLOGY LA English DT Article ID HANTAVIRUS-PULMONARY-SYNDROME; M-SEGMENT REASSORTMENT; HIDDEN MARKOV MODEL; GENETIC-CHARACTERIZATION; MOLECULAR EPIDEMIOLOGY; VIRUSES BUNYAVIRIDAE; COMPLETE GENOMES; NSS PROTEIN; S-SEGMENT; PREDICTION AB Genomic and antigenic characterization of members of the Sandfly fever Naples virus (SFNV) complex reveals the presence of five clades that differ in their geographical distribution. Saint Floris and Gordil viruses, both found in Africa, form one clade; Punique, Granada and Massilia viruses, all isolated in the western Mediterranean, constitute a second; Toscana virus, a third; SFNV isolates from Italy, Cyprus, Egypt and India form a fourth; while Tehran virus and a Serbian isolate Yu 8/76, represent a fifth. Interestingly, this last clade appears not to express the second non-structural protein ORF. Karimabad virus, previously classified as a member of the SFNV complex, and Gabek Forest virus are distinct and form a new species complex (named Karimabad) in the Phlebovirus genus. In contrast with the high reassortment frequency observed in some South American phleboviruses, the only virus of the SFNV complex with evidence of reassortment was Granada virus. C1 [Palacios, Gustavo; Ladner, Jason] US Army Med Res Inst Infect Dis, Ctr Genom Sci, Frederick, MD 21701 USA. [Tesh, Robert B.; da Rosa, Amelia P. A. Travassos; Guzman, Hilda] Univ Texas Med Branch, Dept Pathol, Ctr Biodef & Emerging Infect Dis, Galveston, TX 77555 USA. [Savji, Nazir; Bussetti, Ana Valeria; Desai, Aaloki; Lipkin, W. Ian] Columbia Univ, Mailman Sch Publ Hlth, Ctr Infect & Immun, New York, NY USA. [Sanchez-Seco, Maripaz] Inst Salud Carlos III, Ctr Nacl Microbiol, Madrid, Spain. RP Palacios, G (reprint author), US Army Med Res Inst Infect Dis, Ctr Genom Sci, Frederick, MD 21701 USA. EM gustavo.f.palacios.ctr@us.army.mil RI Palacios, Gustavo/I-7773-2015 OI Palacios, Gustavo/0000-0001-5062-1938 FU Defense Threat Reduction Agency [1881290]; United States Department of Defense, Google.org, National Institutes of Health [AI57158]; USAID PREDICT [07-301-7119-52258]; NIH [HHSN2722010000401/HHSN27200004/DO4] FX This work was supported by the Defense Threat Reduction Agency Project no. 1881290, and the United States Department of Defense, Google.org, National Institutes of Health award AI57158 (Northeast Biodefense Center - Lipkin), and USAID PREDICT funding source code 07-301-7119-52258 (Center for Infection and Immunity). R. T., A. T. R. and H. G. were supported by NIH contract HHSN2722010000401/HHSN27200004/DO4. NR 57 TC 14 Z9 14 U1 0 U2 1 PU SOC GENERAL MICROBIOLOGY PI READING PA MARLBOROUGH HOUSE, BASINGSTOKE RD, SPENCERS WOODS, READING RG7 1AG, BERKS, ENGLAND SN 0022-1317 EI 1465-2099 J9 J GEN VIROL JI J. Gen. Virol. PD FEB PY 2014 VL 95 BP 292 EP 300 DI 10.1099/vir.0.056614-0 PN 2 PG 9 WC Biotechnology & Applied Microbiology; Virology SC Biotechnology & Applied Microbiology; Virology GA AK1LU UT WOS:000338177400004 PM 24096318 ER PT J AU Katz, A Wissink, AM AF Katz, Aaron Wissink, Andrew M. TI Efficient Solution Methods for Strand Grid Applications SO AIAA JOURNAL LA English DT Article ID ARTIFICIAL DIFFUSION; NUMERICAL SCHEMES; GAS-DYNAMICS; ACCURACY; DESIGN AB The strand-Cartesian grid approach offers many advantages in terms of automation, efficiency, and accuracy for complex moving-body problems, such as rotorcraft. In this study, the solution procedures for strand grids are investigated by testing a variety of explicit, implicit, and hybrid methods on canonical aerodynamics test cases involving inviscid and viscous flows in three dimensions. A novel multigrid algorithm is formulated that acts at both the nonlinear pseudotime level and the linear level using line Gauss-Seidel sweeps. Various approximations are tested for the Jacobian, and the impacts on memory and convergence are quantified. The major result is that implicit schemes with first-order approximate Jacobians employing few Gauss-Seidel sweeps are most efficient for strand grids. The improvement by using the multigrid algorithm is significant for all cases tested and indicates O(n) convergence. C1 [Katz, Aaron] Utah State Univ, Logan, UT 84322 USA. [Wissink, Andrew M.] NASA, Ames Res Ctr, US Army Aeroflightdynam Directorate, Moffett Field, CA 94035 USA. RP Katz, A (reprint author), Utah State Univ, Logan, UT 84322 USA. RI Katz, Aaron/I-8244-2015 OI Katz, Aaron/0000-0003-2739-9384 FU Army Research Office Fluid Dynamics Program; U.S. Department of Defense High Performance Computing Modernization Office; U.S. Department of Defense HPC Modernization Program Office FX Development was performed with the support of the Army Research Office Fluid Dynamics Program directed by Frederick Ferguson as well as the HPC Institute for Advanced Rotorcraft Modeling and Simulation located at the U.S. Army Aeroflightdynamics Directorate at Moffett Field, CA, which is supported by the U.S. Department of Defense High Performance Computing Modernization Office. Material presented in this paper is a product of the CREATE-AV Element of the Computational Research and Engineering for Acquisition Tools and Environments Program sponsored by the U.S. Department of Defense HPC Modernization Program Office. NR 21 TC 0 Z9 0 U1 0 U2 1 PU AMER INST AERONAUTICS ASTRONAUTICS PI RESTON PA 1801 ALEXANDER BELL DRIVE, STE 500, RESTON, VA 22091-4344 USA SN 0001-1452 EI 1533-385X J9 AIAA J JI AIAA J. PD FEB PY 2014 VL 52 IS 2 BP 267 EP 280 DI 10.2514/1.J052303 PG 14 WC Engineering, Aerospace SC Engineering GA AJ6KZ UT WOS:000337804700004 ER PT J AU Peck, GW Ferguson, HJ Jones, VP O'Neal, SD Walsh, DB AF Peck, George W. Ferguson, Holly J. Jones, Vincent P. O'Neal, Sally D. Walsh, Douglas B. TI Use of a Highly Sensitive Immunomarking System to Characterize Face Fly (Diptera: Muscidae) Dispersal From Cow Pats SO ENVIRONMENTAL ENTOMOLOGY LA English DT Article DE Musca autumnalis; insect dispersal; mark-recapture ID MUSCA-AUTUMNALIS DIPTERA; POPULATION; CULICIDAE; CATTLE; BRAZIL; SURVIVORSHIP; CALIFORNIA; DOMESTICA; MOVEMENT; SURVIVAL AB We tested an immunomarking system that used egg white as marker and enzyme-linked immunosorbent assay as a detection assay to characterize face fly (Musca autumnalis DeGeer) dispersal from cow pats in a pastured beef cattle operation. In microcage assays, adult flies acquired marker after contact with cow pats that were treated with marker and field aged up to 11 d. In arena assays on sprayed full-size cow pats, 77% of eclosed face flies acquired the marker. In a field- marking study, four applications of egg white marker were applied on freshly deposited cow pats over a summer at two peripheral paddocks to a main grazing pasture of approximate to 50 head of beef cattle. Of the 663 face flies captured, 108 were positive for the egg white marker (16.3%). Of the marked flies, approximate to twofold more male than female flies were captured. Sex-specific dispersal distances were roughly equal up to 450 m, with 11% of female flies dispersing >450 m. Dispersal capability of face flies is discussed in relation to efficacy of rotational grazing and other IPM strategies. C1 [Peck, George W.] Walter Reed Army Inst Res, Vector Control Dept, Entomol Branch, Silver Spring, MD 20910 USA. [Ferguson, Holly J.; O'Neal, Sally D.; Walsh, Douglas B.] Washington State Univ, Environm & Agr Entomol Lab, Irrigated Agr Res & Extens Ctr, Dept Entomol, Prosser, WA 99350 USA. [Jones, Vincent P.] Washington State Univ, Ctr Tree Fruit Res & Extens, Dept Entomol, Wenatchee, WA 98801 USA. RP Peck, GW (reprint author), Walter Reed Army Inst Res, Vector Control Dept, Entomol Branch, 503 Robert Grant Ave, Silver Spring, MD 20910 USA. EM gwpeck5@gmail.com FU USDA Risk Management Assessment (RMA) grant; USDA Pest Management Alternative Program (PMAP) grant FX We thank the staff of the Environmental and Agricultural Entomology Laboratory for their technical assistance. Tawnee Wilburn-Melton, our immune-chemist at the Insect Ecology and Behavior Laboratory, Tree Fruit Research and Extension Center, WSU-Wenatchee, was instrumental to the success of our study. This work was funded by a USDA Risk Management Assessment (RMA) grant and a USDA Pest Management Alternative Program (PMAP) grant to DB Walsh. NR 32 TC 1 Z9 1 U1 1 U2 5 PU OXFORD UNIV PRESS INC PI CARY PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA SN 0046-225X EI 1938-2936 J9 ENVIRON ENTOMOL JI Environ. Entomol. PD FEB PY 2014 VL 43 IS 1 BP 116 EP 122 DI 10.1603/EN13139 PG 7 WC Entomology SC Entomology GA AJ5AR UT WOS:000337693200014 PM 24472203 ER PT J AU Blake, PK Komp, GR AF Blake, Paul K. Komp, Gregory R. TI RADIATION EXPOSURE OF U. S. MILITARY INDIVIDUALS SO HEALTH PHYSICS LA English DT Article DE dose assessment; exposure, occupational; National Council on Radiation Protection and Measurements; radiation, ionizing ID MORTALITY AB The U.S. military consists of five armed services: the Army, Navy, Marine Corps, Air Force, and Coast Guard. It directly employs 1.4 million active duty military, 1.3 million National Guard and reserve military, and 700,000 civilian individuals. This paper describes the military guidance used to preserve and maintain the health of military personnel while they accomplish necessary and purposeful work in areas where they are exposed to radiation. It also discusses military exposure cohorts and associated radiogenic disease compensation programs administered by the U.S. Department of Veterans Affairs, the U.S. Department of Justice, and the U.S. Department of Labor. With a few exceptions, the U.S. military has effectively employed ionizing radiation since it was first introduced during the Spanish-American War in 1898. The U. S military annually monitors 70,000 individuals for occupational radiation exposure: similar to 2% of its workforce. In recent years, the Departments of the Navy (including the Marine Corps), the Army, and the Air Force all have a low collective dose that remains close to 1 person-Sv annually. Only a few Coast Guard individuals are now routinely monitored for radiation exposure. As with the nuclear industry as a whole, the Naval Reactors program has a higher collective dose than the remainder of the U.S. military. The U.S. military maintains occupational radiation exposure records on over two million individuals from 1945 through the present. These records are controlled in accordance with the Privacy Act of 1974 but are available to affected individuals or their designees and other groups performing sanctioned epidemiology studies. C1 [Blake, Paul K.] Def Threat Reduct Agcy, Ft Belvoir, VA 22060 USA. [Komp, Gregory R.] US Army, Ft Belvoir, VA 22060 USA. RP Blake, PK (reprint author), Def Threat Reduct Agcy, 8725 John J Kingman Rd, Ft Belvoir, VA 22060 USA. EM paul.blake@dtra.mil NR 32 TC 4 Z9 4 U1 0 U2 5 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0017-9078 EI 1538-5159 J9 HEALTH PHYS JI Health Phys. PD FEB PY 2014 VL 106 IS 2 BP 272 EP 278 DI 10.1097/HP.0000000000000032 PG 7 WC Environmental Sciences; Public, Environmental & Occupational Health; Nuclear Science & Technology; Radiology, Nuclear Medicine & Medical Imaging SC Environmental Sciences & Ecology; Public, Environmental & Occupational Health; Nuclear Science & Technology; Radiology, Nuclear Medicine & Medical Imaging GA AJ2SO UT WOS:000337512400017 PM 24378502 ER PT J AU Cole, DP Reddy, ALM Hahm, MG McCotter, R Hart, AHC Vajtai, R Ajayan, PM Karna, SP Bundy, ML AF Cole, Daniel P. Reddy, Arava Leela Mohana Hahm, Myung Gwan McCotter, Ryan Hart, Amelia H. C. Vajtai, Robert Ajayan, Pulickel M. Karna, Shashi P. Bundy, Mark L. TI Electromechanical Properties of Polymer Electrolyte-Based Stretchable Supercapacitors SO ADVANCED ENERGY MATERIALS LA English DT Article ID ENERGY-STORAGE APPLICATIONS; MECHANICAL-PROPERTIES; CARBON NANOTUBES; NAFION; COMPOSITES; DEVICES; STATE; PAPER; PERFORMANCE; FILMS C1 [Cole, Daniel P.] Motile Robot Inc, Joppa, MD USA. [Reddy, Arava Leela Mohana; Hahm, Myung Gwan; McCotter, Ryan; Hart, Amelia H. C.; Vajtai, Robert; Ajayan, Pulickel M.] Rice Univ, Dept Mech Engn & Mat Sci, Houston, TX 77251 USA. [Karna, Shashi P.; Bundy, Mark L.] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Bundy, ML (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. EM mark.l.bundy2.civ@mail.mil RI Arava, Leela Mohana Reddy/J-3180-2015; Hahm, Myung Gwan/D-6789-2011 OI Hahm, Myung Gwan/0000-0002-6432-0578 FU U.S. Army Research Laboratory [NNL-09AA00A]; U.S. Army Research Laboratory/Army Research Office [W911NF]; Exotic Nanocarbons, Japan Regional Innovation Strategy Program by the Excellence, Japan Science and Technology Agency; U.S. Department of Defense: U.S. Air Force Office of Scientific Research for the Project MURI: "Synthesis and Charaterization of 3-D Carbon Nanotube Solid Networks" [FA9550-12-1-0035] FX D.P.C. acknowledges financial support from U.S. Army Research Laboratory (contract NNL-09AA00A). A.L.M.R., M.G.H., R.V., and P.M.A. acknowledge financial support from U.S. Army Research Laboratory/Army Research Office (No. W911NF). M.G.H. and P.M.A. acknowledge the support from Exotic Nanocarbons, Japan Regional Innovation Strategy Program by the Excellence, Japan Science and Technology Agency. R.V. and P.M.A. acknowledge funding sponsorship from the U.S. Department of Defense: U.S. Air Force Office of Scientific Research for the Project MURI: "Synthesis and Charaterization of 3-D Carbon Nanotube Solid Networks" award no.: FA9550-12-1-0035. NR 33 TC 7 Z9 7 U1 2 U2 43 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY SN 1614-6832 EI 1614-6840 J9 ADV ENERGY MATER JI Adv. Energy Mater. PD FEB PY 2014 VL 4 IS 3 AR 1300844 DI 10.1002/aenm.201300844 PG 5 WC Chemistry, Physical; Energy & Fuels; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter SC Chemistry; Energy & Fuels; Materials Science; Physics GA AB3SG UT WOS:000331709900002 ER PT J AU del Rincon, I Battafarano, DF Restrepo, JF Erikson, JM Escalante, A AF del Rincon, Inmaculada Battafarano, Daniel F. Restrepo, Jose F. Erikson, John M. Escalante, Agustin TI Glucocorticoid Dose Thresholds Associated With All-Cause and Cardiovascular Mortality in Rheumatoid Arthritis SO ARTHRITIS & RHEUMATOLOGY LA English DT Article ID POPULATION-BASED COHORT; PROPENSITY SCORE; ADVERSE EVENTS; DISEASE; COMORBIDITY; PREDICTORS; SEVERITY; SURVIVAL; THERAPY; DEATH AB Objective. To delineate daily and cumulative glucocorticoid dose thresholds associated with increased mortality rates in rheumatoid arthritis (RA). Methods. We studied RA patients recruited from rheumatology clinics. Annually, we assessed the glucocorticoid dose, demographic, socioeconomic, clinical, and laboratory features of RA, cardiovascular (CV) risk factors, and vital status. We used Cox proportional hazards regression to assess associations between the daily or cumulative glucocorticoid dose and death, adjusting for potential confounders and for the propensity to receive glucocorticoids. We tested strata of the glucocorticoid dose to delineate the threshold associated with death. Results. We studied 779 RA patients with a total of 7,203 person-years of observation, during which 237 of them died, yielding a mortality rate of 3.2 per 100 person-years (95% confidence interval [95% CI] 2.8-3.7). One hundred twenty of the deaths were due to CV causes, yielding a CV mortality rate of 1.8 (95% CI 1.5-2.1). Exposure to glucocorticoids was associated with a dose-dependent increase in death from all causes, with a ratio (HR) of 1.07 per mg of prednisone per day (95% CI 1.05-1.08). Compared to patients who were not receiving corticosteroids, the minimum daily prednisone dose threshold associated with an increase in all-cause mortality was 8-15 mg, with an adjusted HR of 1.78 (95% CI 1.22-2.60). For the cumulative dose of gluco-corticoids, the minimum dosage associated with allcause mortality was 40 gm (HR 1.74 [95% CI 1.25-2.44]). Conclusion. Glucocorticoid use in RA is associated with a dose-dependent increase in mortality rates, with a daily threshold dose of 8 mg, at which the number of deaths increased in a dose-dependent manner. These findings may assist clinicians in selecting the appropriate glucocorticoid dosage for RA patients who require these agents. C1 [del Rincon, Inmaculada; Restrepo, Jose F.; Erikson, John M.; Escalante, Agustin] Univ Texas Hlth Sci Ctr San Antonio, San Antonio, TX 78229 USA. [Battafarano, Daniel F.] Brooke Army Med Ctr, Ft Sam Houston, TX 78234 USA. RP del Rincon, I (reprint author), Univ Texas Hlth Sci Ctr San Antonio, 7703 Floyd Curl Dr,MC 7874, San Antonio, TX 78229 USA. EM delrincon@uthscsa.edu FU NIH [R01-HL-085742, R01-HD-37151, K23-HL-004481, UL1-RR-025767] FX Supported in part by the NIH (grants R01-HL-085742, R01-HD-37151, K23-HL-004481, and UL1-RR-025767). NR 31 TC 36 Z9 37 U1 0 U2 0 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 2326-5191 EI 2326-5205 J9 ARTHRITIS RHEUMATOL JI Arthritis Rheumatol. PD FEB PY 2014 VL 66 IS 2 BP 264 EP 272 DI 10.1002/art.38210 PG 9 WC Rheumatology SC Rheumatology GA AJ0PQ UT WOS:000337357900006 PM 24504798 ER PT J AU Barnes, JN Hart, EC Curry, TB Nicholson, WT Eisenach, JH Wallin, BG Charkoudian, N Joyner, MJ AF Barnes, Jill N. Hart, Emma C. Curry, Timothy B. Nicholson, Wayne T. Eisenach, John H. Wallin, B. Gunnar Charkoudian, Nisha Joyner, Michael J. TI Aging Enhances Autonomic Support of Blood Pressure in Women SO HYPERTENSION LA English DT Article DE blood pressure; menopause; sympathetic nerve activity ID SYMPATHETIC-NERVE ACTIVITY; GANGLIONIC BLOCKADE; GENDER-DIFFERENCES; ARTERIAL-PRESSURE; SEX-DIFFERENCES; AGE; SENSITIVITY; MODULATION; BALANCE; HUMANS AB The autonomic nervous system plays a central role in both acute and chronic blood pressure regulation in humans. The activity of the sympathetic branch of the autonomic nervous system is positively associated with peripheral resistance, an important determinant of mean arterial pressure in men. In contrast, there is no association between sympathetic nerve activity and peripheral resistance in women before menopause, yet a positive association after menopause. We hypothesized that autonomic support of blood pressure is higher after menopause in women. We examined the effect of ganglionic blockade on arterial blood pressure and how this relates to baseline muscle sympathetic nerve activity in 12 young (25 +/- 1 years) and 12 older postmenopausal (61 +/- 2 years) women. The women were studied before and during autonomic blockade using trimethaphan camsylate. At baseline, muscle sympathetic nerve activity burst frequency and burst incidence were higher in the older women (33 +/- 3 versus 15 +/- 1 bursts/min; 57 +/- 5 versus 25 +/- 2 bursts/100 heartbeats, respectively; P<0.05). Muscle sympathetic nerve activity bursts were abolished by trimethaphan within minutes. Older women had a greater decrease in mean arterial pressure (-29 +/- 2 versus -9 +/- 2 mm Hg; P<0.01) and total peripheral resistance (-10 +/- 1 versus -5 +/- 1 mm Hg/L per minute; P<0.01) during trimethaphan. Baseline muscle sympathetic nerve activity was associated with the decrease in mean arterial pressure during trimethaphan (r=-0.74; P<0.05). In summary, our results suggest that autonomic support of blood pressure is greater in older women compared with young women and that elevated sympathetic nerve activity in older women contributes importantly to the increased incidence of hypertension after menopause. C1 [Barnes, Jill N.; Hart, Emma C.; Curry, Timothy B.; Nicholson, Wayne T.; Eisenach, John H.; Joyner, Michael J.] Mayo Clin, Dept Anesthesiol, Rochester, MN 55905 USA. [Wallin, B. Gunnar] Gothenburg Univ, Sahlgren Acad, Inst Neurosci & Physiol, Gothenburg, Sweden. [Charkoudian, Nisha] US Army Res Inst Environm Med, Thermal & Mt Med Div, Natick, MA USA. RP Barnes, JN (reprint author), Mayo Clin, Dept Anesthesiol, SMH, 200 1st St SW,Joseph 4-184, Rochester, MN 55905 USA. EM Barnes.Jill@mayo.edu OI Hart, Emma/0000-0002-4534-9586 FU National Institutes of Health [RR024150, AG038067, HL083947]; American Heart Association [2170087] FX Funding was provided by National Institutes of Health grants RR024150 (Center for Translational Science Activities), AG038067 (J.N. Barnes), AR056950 (J.N. Barnes), and HL083947 (B.G. Wallin, N. Charkoudian, M.J. Joyner) and American Heart Association grant 2170087 (E.C. Hart). NR 28 TC 23 Z9 23 U1 0 U2 2 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0194-911X EI 1524-4563 J9 HYPERTENSION JI Hypertension PD FEB PY 2014 VL 63 IS 2 BP 303 EP 308 DI 10.1161/HYPERTENSIONAHA.113.02393 PG 6 WC Peripheral Vascular Disease SC Cardiovascular System & Cardiology GA AI9UH UT WOS:000337284500026 PM 24324040 ER PT J AU Ching, MS Kuwabara, N AF Ching, Michael S. Kuwabara, Norimitsu TI Who Is Referred for Developmental Evaluation When Parents Are Concerned? SO JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS LA English DT Meeting Abstract C1 [Ching, Michael S.] Tripler Army Med Ctr, Honolulu, HI 96859 USA. [Kuwabara, Norimitsu] Univ Hawaii, John A Burns Sch Med, Honolulu, HI 96822 USA. NR 0 TC 0 Z9 0 U1 1 U2 2 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0196-206X EI 1536-7312 J9 J DEV BEHAV PEDIATR JI J. Dev. Behav. Pediatr. PD FEB-MAR PY 2014 VL 35 IS 2 MA 21 BP S6 EP S6 PG 1 WC Behavioral Sciences; Psychology, Developmental; Pediatrics SC Behavioral Sciences; Psychology; Pediatrics GA AI4QL UT WOS:000336849800022 ER PT J AU Lozito, TP Jackson, WM Nesti, LJ Tuan, RS AF Lozito, Thomas P. Jackson, Wesley M. Nesti, Leon J. Tuan, Rocky S. TI Human mesenchymal stem cells generate a distinct pericellular zone of MMP activities via binding of MMPs and secretion of high levels of TIMPs SO MATRIX BIOLOGY LA English DT Article DE Mesenchymal stem cells (MSCs); Matrix metalloprotease (MMP); Tissue inhibitors of metalloprotease (TIMP) ID HUMAN BONE-MARROW; MATRIX METALLOPROTEINASES; TISSUE-INHIBITOR; PROGENITOR CELLS; STROMAL CELLS; SKIN CARCINOGENESIS; GELATINASE-A; DENTAL-PULP; DIFFERENTIATION; ACTIVATION AB Mesenchymal stem cells (MSCs) are attractive candidates for inclusion in cell-based therapies by virtue of their abilities to home to wound sites. However, in-depth characterization of the specific effects of MSCs on their microenvironments is needed to realize their full therapeutic potentials. Furthermore, since MSCs of varying properties can be isolated from a diverse spectrum of tissues, a strategic and rational approach in MSC sourcing for a particular application has yet to be achieved. For example, MSCs that activate their proteolytic environments may promote tissue remodeling, while those from different tissue sources may inhibit proteases and promote tissue stabilization. This study attempts to address these issues by analyzing MSCs isolated from three adult tissue sources in terms of their effects on their proteolytic microenvironments. Human bone marrow, adipose, and traumatized muscle derived MSCs were compared in their soluble and cellular-associated MMP components and activity. For all types of MSCs, MMP activity associated with the cell surface, but activity levels and MMP profiles differed with tissue source. All MSC types bound exogenous active MMPs at their surfaces. MSCs were also able to activate exogenous proMMP-2 and proMMP-13. This is in marked contrast to the MSC soluble compartment, which strongly inhibited MMPs via endogenous TIMPs. The exact TIMP used to inhibit the exogenous MMP differed with MSC type. Thus, MSCs saturate their environment with both MMPs and TIMPs. Since they bind and activate MMPs at their surfaces, the net result is a very controlled pericellular localization of MMP activities by MSCs. (C) 2013 Elsevier B.V. All rights reserved. C1 [Lozito, Thomas P.; Tuan, Rocky S.] Univ Pittsburgh, Sch Med, Dept Orthopaed Surg, Ctr Cellular & Mol Engn, Pittsburgh, PA 15261 USA. [Jackson, Wesley M.; Nesti, Leon J.] NIAMSD, Orthopaed Res Grp, NIH, US Dept HHS, Bethesda, MD 20892 USA. [Nesti, Leon J.] Walter Reed Army Med Ctr, Dept Orthopaed & Rehabil, Washington, DC 20307 USA. [Nesti, Leon J.] Uniformed Serv Univ Hlth Sci, Dept Surg, Bethesda, MD 20814 USA. RP Tuan, RS (reprint author), Ctr Cellular & Mol Engn, Dept Orthopaed Surg, 450 Technol Dr,Room 221, Pittsburgh, PA 15219 USA. EM rst13@pitt.edu FU Department of Defense [W81XWH-10-1-0850]; Military Amputee Research Program at WRAMC [PO5-A011]; Commonwealth of Pennsylvania Department of Health FX This project was supported by grants from the Department of Defense (W81XWH-10-1-0850), the Military Amputee Research Program at WRAMC (PO5-A011), and the Commonwealth of Pennsylvania Dept Anent of Health. NR 53 TC 16 Z9 16 U1 1 U2 9 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0945-053X EI 1569-1802 J9 MATRIX BIOL JI Matrix Biol. PD FEB PY 2014 VL 34 BP 132 EP 143 DI 10.1016/j.matbio.2013.10.003 PG 12 WC Biochemistry & Molecular Biology; Cell Biology SC Biochemistry & Molecular Biology; Cell Biology GA AH9PD UT WOS:000336473400014 PM 24140982 ER PT J AU Schake, K AF Schake, Kori TI Lessons from the Indian Wars SO POLICY REVIEW LA English DT Article C1 [Schake, Kori] Hoover Inst War Revolut & Peace, Stanford, CA 94305 USA. [Schake, Kori] US Mil Acad, West Point, NY USA. RP Schake, K (reprint author), Hoover Inst War Revolut & Peace, Stanford, CA 94305 USA. NR 0 TC 0 Z9 0 U1 1 U2 1 PU HOOVER INST PI STANFORD PA STANFORD UNIV, STANFORD, CA 94305-601 USA SN 0146-5945 J9 POLICY REV JI Policy Rev. PD FEB-MAR PY 2014 IS 177 BP 71 EP 79 PG 9 WC Political Science SC Government & Law GA AI1UO UT WOS:000336640800006 ER PT J AU Atwater, MA Darling, KA Tschopp, MA AF Atwater, Mark A. Darling, Kris A. Tschopp, Mark A. TI Towards Reaching the Theoretical Limit of Porosity in Solid State Metal Foams: Intraparticle Expansion as A Primary and Additive Means to Create Porosity SO ADVANCED ENGINEERING MATERIALS LA English DT Article ID NANOCRYSTALLINE COPPER; POROUS COPPER; TITANIUM; ELECTRODEPOSITION; REDUCTION; STABILITY; ANTIMONY; CUO C1 [Atwater, Mark A.; Darling, Kris A.; Tschopp, Mark A.] US Army, Res Lab, Weap & Mat Res Directorate, Lightweight & Specialty Met Branch, Aberdeen Proving Ground, MD 21005 USA. [Atwater, Mark A.] Millersville Univ Pennsylvania, Dept Appl Engn Safety & Technol, Millersville, PA 17551 USA. RP Atwater, MA (reprint author), US Army, Res Lab, Weap & Mat Res Directorate, Lightweight & Specialty Met Branch, Aberdeen Proving Ground, Aberdeen Proving Ground, MD 21005 USA. EM mark.atwater@millersville.edu OI Tschopp, Mark/0000-0001-8471-5035 NR 30 TC 2 Z9 2 U1 2 U2 12 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY SN 1438-1656 EI 1527-2648 J9 ADV ENG MATER JI Adv. Eng. Mater. PD FEB PY 2014 VL 16 IS 2 BP 190 EP 195 DI 10.1002/adem.201300431 PG 6 WC Materials Science, Multidisciplinary SC Materials Science GA AB7JE UT WOS:000331965000011 ER PT J AU Tiba, MH Draucker, GT Barbee, RW Terner, J Torres, I Torres, I Vakhshoori, D Ward, KR AF Tiba, Mohamad H. Draucker, Gerard T. Barbee, Robert W. Terner, James Torres Filho, Ivo Romfh, Padraic Vakhshoori, Daryoosh Ward, Kevin R. TI Tissue oxygenation monitoring using resonance Raman spectroscopy during hemorrhage SO JOURNAL OF TRAUMA AND ACUTE CARE SURGERY LA English DT Article DE Hemorrhagic shock; tissue hemoglobin oxygen saturation; resonance Raman spectroscopy; near-infrared spectroscopy; noninvasive monitoring; swine ID NEAR-INFRARED SPECTROSCOPY; HUMAN SKELETAL-MUSCLE; TRAUMA PATIENTS; SATURATION PREDICTS; SHOCK RESUSCITATION; END-POINTS; HEMOGLOBIN; MYOGLOBIN; TECHNOLOGY; EMERGENCY AB BACKGROUND: The ability to monitor the patient of hemorrhage noninvasively remains a challenge. We examined the ability of resonance Raman spectroscopy to monitor tissue hemoglobin oxygenation (RRS-StO(2)) during hemorrhage and compared its performance with conventional invasive mixed venous (SmvO(2)) and central venous (ScvO(2)) hemoglobin oxygen saturation as well as with near-infrared spectroscopy tissue hemoglobin oxygenation (NIRS-StO(2)). METHODS: Five male swine were anesthetized and instrumented followed by hemorrhage at a rate of 30 mL/min for 60 minutes. RRS-StO(2) was continuously measured from the buccal mucosa, and NIRS-StO(2) was continuously measured from the forelimb. Paired interval measures of SmvO(2), ScvO(2), and lactate were made. Pearson correlation was used to quantify the degree to which any two variables are related. Receiver operating characteristic (ROC) area under the curve values were used for pooled data for RRS-StO(2), NIRS-StO(2), SmvO(2), and ScvO(2) to compare performance in the ability of tissue oxygenation methods to predict the presence of an elevated arterial blood lactate level. RESULTS: Sequential RRS-StO(2) changes tracked changes in SmvO(2) (r = 0.917; 95% confidence interval [CI], 0.867-0.949) and ScvO(2) (r = 0.901; 95% CI, 0.828-0.944) during hemorrhage, while NIRS-StO(2) failed to do so for SmvO(2) (r = 0.283; 95% CI, 0.04919-0.4984) and ScvO(2) (r = 0.142; 95% CI, -0.151 to 0.412). ROC curve performance of oxygenation measured to indicate lactate less than or greater than 3 mM yielded the following ROC area under the curve values: SmvO(2) (1.0), ScvO(2) (0.994), RRS-StO(2) (0.972), and NIRS-StO(2) (0.611). CONCLUSION: RRS-StO(2) seems to have significantly better ability to track central oxygenation measures during hemorrhage as well as to predict shock based on elevated lactate levels when compared with NIRS-StO(2). Copyright (C) 2014 by Lippincott Williams & Wilkins C1 [Tiba, Mohamad H.; Draucker, Gerard T.; Ward, Kevin R.] Univ Michigan, Dept Emergency Med, Ann Arbor, MI 48109 USA. [Tiba, Mohamad H.; Draucker, Gerard T.; Ward, Kevin R.] Univ Michigan, Michigan Ctr Integrat Res Crit Care, Ann Arbor, MI 48109 USA. [Barbee, Robert W.] Virginia Commonwealth Univ, Dept Emergency Med, Richmond, VA USA. [Terner, James] Virginia Commonwealth Univ, Dept Chem, Richmond, VA USA. [Barbee, Robert W.; Terner, James] Virginia Commonwealth Univ, Reanimat Engn Sci Ctr, Richmond, VA USA. [Torres Filho, Ivo] US Army Inst Surg Res, Ft Sam Houston, TX USA. [Romfh, Padraic; Vakhshoori, Daryoosh] Pendar Med, Cambridge, MA USA. RP Ward, KR (reprint author), Univ Michigan, Michigan Ctr Integrat Res Crit Care, 2800 Plymouth Rd,10-103A, Ann Arbor, MI 48109 USA. EM keward@umich.edu NR 41 TC 5 Z9 5 U1 5 U2 10 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 2163-0755 EI 2163-0763 J9 J TRAUMA ACUTE CARE JI J. Trauma Acute Care Surg. PD FEB PY 2014 VL 76 IS 2 BP 402 EP 408 PG 7 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA AH8KG UT WOS:000336386100021 PM 24378619 ER PT J AU Klapotke, TM Mehta, N AF Klapoetke, Thomas M. Mehta, Neha TI Lead-free Primary Explosives SO PROPELLANTS EXPLOSIVES PYROTECHNICS LA English DT Editorial Material C1 [Klapoetke, Thomas M.] Univ Munich, Dept Chem Energet Mat Res, D-81377 Munich, Germany. [Mehta, Neha] US Army, RDECOM ARDEC, Explos Dev Branch, Adelphi, MD USA. RP Klapotke, TM (reprint author), Univ Munich, Dept Chem Energet Mat Res, Marchioninistr 15, D-81377 Munich, Germany. RI Klapoetke, Thomas/B-6055-2014 OI Klapoetke, Thomas/0000-0003-3276-1157 NR 0 TC 18 Z9 18 U1 1 U2 18 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY SN 0721-3115 EI 1521-4087 J9 PROPELL EXPLOS PYROT JI Propellants Explos. Pyrotech. PD FEB PY 2014 VL 39 IS 1 BP 7 EP 8 DI 10.1002/prep.201480132 PG 2 WC Chemistry, Applied; Engineering, Chemical SC Chemistry; Engineering GA AB7NQ UT WOS:000331977700001 ER PT J AU McNesby, KL Biss, MM Benjamin, RA Thompson, RA AF McNesby, Kevin L. Biss, Matthew M. Benjamin, Richard A. Thompson, Ronnie A. TI Optical Measurement of Peak Air Shock Pressures Following Explosions SO PROPELLANTS EXPLOSIVES PYROTECHNICS LA English DT Article DE Shock pressure; Optical measurement; Explosions; Near field AB High speed video and streak camera imaging are used to measure peak pressures for explosions of spherical charges of the high explosive C-4 (92% trimethylenetrinitramine, C3H6N6O6). The technique measures the velocity of the air shock produced by the detonation of the explosive charges, converts this velocity to a Mach number, and uses the Mach number to determine a peak shock pressure. Peak pressure measurements are reported from a few millimeters to approximately one meter from the charge surface. Optical peak pressure measurements are compared to peak pressures measured using piezoelectric pressure transducers, and to peak pressure measurements estimated using the blast computer code CONWEP. A discussion of accuracy of peak pressures determined optically is provided. C1 [McNesby, Kevin L.; Biss, Matthew M.; Benjamin, Richard A.; Thompson, Ronnie A.] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP McNesby, KL (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. EM mcnesby@arl.army.mil NR 12 TC 3 Z9 3 U1 1 U2 5 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY SN 0721-3115 EI 1521-4087 J9 PROPELL EXPLOS PYROT JI Propellants Explos. Pyrotech. PD FEB PY 2014 VL 39 IS 1 BP 59 EP 64 DI 10.1002/prep.201300023 PG 6 WC Chemistry, Applied; Engineering, Chemical SC Chemistry; Engineering GA AB7NQ UT WOS:000331977700009 ER PT J AU Anderson, PE Cook, P Davis, A Mychajlonka, K Mileham, M AF Anderson, Paul E. Cook, Paula Davis, Andy Mychajlonka, Kyle Mileham, Melissa TI Silicon Fuel in High Performance Explosives SO PROPELLANTS EXPLOSIVES PYROTECHNICS LA English DT Article DE Silicon; Multiuse explosives; Cylinder test; Gurney AB In an effort to improve the insensitive munition (IM) response but maintain performance of aluminized formulations, silicon was investigated as a possible replacement for aluminum. An RDX-based silicon explosive was developed in which nearly 90% reaction of silicon to silicon dioxide was realized by 7 volume expansions as measured by the 2.54cm diameter copper cylinder expansion test. In spite of the low nitramine loading in the formulation (79wt.-%), the corresponding Gurney constant for the explosive was 2.81 +/- 0.02kms(-1), which is superior to Composition A-3 under the same experimental conditions (91% RDX, 2.69 +/- 0.02kms(-1)). Energy calculations from detonation calorimetry also indicate reaction of the silicon, which was further confirmed by both silicon metal and silicon dioxide in the analyzed residue. The energy release, despite it being equivalent to a highly loaded explosive, was found to lag behind the rate of A-3. This indicates silicon oxidation may occur sometime after lighter gas reactions in the reaction front, but is fast enough to impart work in the copper cylinder test. C1 [Anderson, Paul E.; Cook, Paula] US Army ARDEC, Picatinny Arsenal, NJ 07806 USA. [Davis, Andy; Mychajlonka, Kyle] Nammo Talley Res & Dev, Mesa, AZ 85277 USA. [Mileham, Melissa] ATK Thiokol, Brigham City, UT 84302 USA. RP Anderson, PE (reprint author), US Army ARDEC, Picatinny Arsenal, NJ 07806 USA. EM paul.e.anderson64.civ@mail.mil FU Scalable Technology for Adaptive Response (STAR) Army Technology Objective (ATO) Technology Program FX The authors gratefully acknowledge the guidance of Dr. Ernest L. Baker and Dr. Leonard Stiel of New York Polytechnic Institute for calculation of the EOS, Erik Wrobel, Gerard Gillen, and Mike VandeWal for the detonation testing, Ralph Acevedo and Terry Barhite for pressing of the test samples, Joel Rivera for sensitivity testing, and Henry Grau for compatibility tests. Funding was provided by the Scalable Technology for Adaptive Response (STAR) Army Technology Objective (ATO) Technology Program. NR 12 TC 3 Z9 4 U1 1 U2 6 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY SN 0721-3115 EI 1521-4087 J9 PROPELL EXPLOS PYROT JI Propellants Explos. Pyrotech. PD FEB PY 2014 VL 39 IS 1 BP 74 EP 78 DI 10.1002/prep.201300077 PG 5 WC Chemistry, Applied; Engineering, Chemical SC Chemistry; Engineering GA AB7NQ UT WOS:000331977700011 ER PT J AU Sherrill, WM Johnson, EC Paraskos, AJ AF Sherrill, William M. Johnson, Eric C. Paraskos, Alexander J. TI Synthesis and Characterization of Mono-, Di-, and Tetranitrated 7,8-Disubstituted Glycolurils SO PROPELLANTS EXPLOSIVES PYROTECHNICS LA English DT Article DE Substituted glycoluril; Tetranitroglycolurils; Nitration; Computational analysis ID QUANTUM-MECHANICAL CALCULATIONS; HEATS AB Three 7,8-disubstitited glycolurils were synthesized and subjected to various nitration conditions yielding the corresponding mono-, di-, and tetranitro derivatives. Prior to their synthesis, these nitrated compounds were evaluated computationally to determine their densities and heats of formation, from which explosive performance was predicted. Details on the methods used for the synthesis as well as the results from their computational analysis are discussed. C1 [Sherrill, William M.] US Army Res Lab ARL, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. [Johnson, Eric C.] Bowhead Sci & Technol, Belcamp, MD 21017 USA. [Paraskos, Alexander J.] US Army Armament Res Dev & Engn Ctr ARDEC, Picatinny Arsenal, NJ 07806 USA. RP Sherrill, WM (reprint author), US Army Res Lab ARL, Weap & Mat Res Directorate, Bldg 1119B,Spesutie Isl Rd, Aberdeen Proving Ground, MD 21005 USA. EM william.m.sherrill.civ@mail.mil NR 15 TC 5 Z9 5 U1 1 U2 14 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY SN 0721-3115 EI 1521-4087 J9 PROPELL EXPLOS PYROT JI Propellants Explos. Pyrotech. PD FEB PY 2014 VL 39 IS 1 BP 90 EP 94 DI 10.1002/prep.201300048 PG 5 WC Chemistry, Applied; Engineering, Chemical SC Chemistry; Engineering GA AB7NQ UT WOS:000331977700013 ER PT J AU Miklaszewski, EJ Poret, JC Shaw, AP Son, SF Groven, LJ AF Miklaszewski, Eric J. Poret, Jay C. Shaw, Anthony P. Son, Steven F. Groven, Lori J. TI Ti/C-3Ni/Al as a Replacement Time Delay Composition SO PROPELLANTS EXPLOSIVES PYROTECHNICS LA English DT Article DE Delay fuze; Microchannels; Critical diameter; Stability; Combustion synthesis ID COMBUSTION SYNTHESIS AB Replacement reactive systems for the tungsten delay composition (W/BaCrO4/KClO4/diatomaceous earth) are needed due to recent concerns over the toxicity of hexavalent chromium and perchlorates. Systems based on condensed phase reactions, that are typically used in combustion synthesis (e.g., Ti/C or Ni/Al) are of interest as replacements due to their wide range of combustion velocities and potentially low environmental impact. In this work, the combustion characteristics of the Ti/C-3Ni/Al reactive system were examined in microchannels with inner diameters ranging from 3.0-6.0mm (i.e., similar to that of a common delay housing). It was found that this reactive system could be tailored to overcome the heat losses associated with small diameter microchannels by changing the relative amounts of Ti/C and 3Ni/Al. At 40wt.-% Ti/C content, the failure diameter was found to be between 3.0 and 4.0mm, while at 30wt.-% Ti/C the failure diameter was between 4.8 and 6.0mm. Measured combustion temperatures in metal microchannels were approximately 1700K while those of unconfined pellets were around 100K greater. Increasing Ti/C content resulted in faster combustion velocities while decreasing microchannel diameter resulted in slower combustion velocities. At these small sizes the effects of adding a thermal barrier (specifically Grafoil) to minimize radial heat losses to the microchannel were shown to be minimal with respect to combustion velocity. The Ti/C-3Ni/Al system was shown to be a suitable delay fuze composition with tunable combustion velocities ranging from 2.1-38.1mms(-1) in aluminum microchannels with diameters ranging from 4.0-6.0mm. C1 [Miklaszewski, Eric J.; Son, Steven F.; Groven, Lori J.] Purdue Univ, Sch Mech Engn, W Lafayette, IN 47907 USA. [Poret, Jay C.; Shaw, Anthony P.] US Army RDECOM ARDEC, Pyrotech Technol & Prototyping Div, Picatinny Arsenal, NJ USA. RP Miklaszewski, EJ (reprint author), Purdue Univ, Sch Mech Engn, W Lafayette, IN 47907 USA. EM lori.groven@sdsmt.edu FU Purdue University by the US Army RDECOM Environmental Quality Technology Program via the Armament Research, Development and Engineering Center [W15QKN-09-C-0121] FX This work was supported at Purdue University by the US Army RDECOM Environmental Quality Technology Program via the Armament Research, Development and Engineering Center under Contract #W15QKN-09-C-0121. The authors would like to thank Prof. Timothee Pourpoint for the use of his MATLAB code for the analysis of high speed images. NR 26 TC 6 Z9 6 U1 1 U2 7 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA POSTFACH 101161, 69451 WEINHEIM, GERMANY SN 0721-3115 EI 1521-4087 J9 PROPELL EXPLOS PYROT JI Propellants Explos. Pyrotech. PD FEB PY 2014 VL 39 IS 1 BP 138 EP 147 DI 10.1002/prep.201300099 PG 10 WC Chemistry, Applied; Engineering, Chemical SC Chemistry; Engineering GA AB7NQ UT WOS:000331977700020 ER PT J AU Gardony, AL Taylor, HA Brunye, TT AF Gardony, Aaron L. Taylor, Holly A. Brunye, Tad T. TI What Does Physical Rotation Reveal About Mental Rotation? SO PSYCHOLOGICAL SCIENCE LA English DT Article DE mental models; motor processes; spatial perception ID WORKING-MEMORY CAPACITY; NEURAL MECHANISMS; MOTOR PROCESSES; STRATEGIES; OBJECTS; FIGURES; EYE AB In a classic psychological science experiment, Shepard and Metzler (1971) discovered that the time participants took to judge whether two rotated abstract block figures were identical increased monotonically with the figures' relative angular disparity. They posited that participants rotate mental images to achieve a match and that mental rotation recruits motor processes. This interpretation has become central in the literature, but until now, surprisingly few researchers have compared mental and physical rotation. We had participants rotate virtual Shepard and Metzler figures mentally and physically; response time, accuracy, and real-time rotation data were collected. Results suggest that mental and physical rotation processes overlap and also reveal novel conclusions about physical rotation that have implications for mental rotation. Notably, participants did not rotate figures to achieve a match, but rather until they reached an off-axis canonical difference, and rotational strategies markedly differed for judgments of whether the figures were the same or different. C1 [Gardony, Aaron L.; Taylor, Holly A.; Brunye, Tad T.] Tufts Univ, Dept Psychol, Medford, MA 02155 USA. [Gardony, Aaron L.; Brunye, Tad T.] US Army Natick Soldier Res, Ctr Dev & Engn, Cognit Sci Team, Natick, MA USA. RP Gardony, AL (reprint author), Tufts Univ, 490 Boston Ave, Medford, MA 02155 USA. EM agardony@gmail.com NR 30 TC 3 Z9 3 U1 1 U2 14 PU SAGE PUBLICATIONS INC PI THOUSAND OAKS PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA SN 0956-7976 EI 1467-9280 J9 PSYCHOL SCI JI Psychol. Sci. PD FEB PY 2014 VL 25 IS 2 BP 605 EP 612 DI 10.1177/0956797613503174 PG 8 WC Psychology, Multidisciplinary SC Psychology GA AH6AJ UT WOS:000336212800033 PM 24311475 ER PT J AU Morrison, JJ Ross, JD Houston, R Watson, DB Sokol, KK Rasmussen, TE AF Morrison, Jonathan J. Ross, James D. Houston, Robert Watson, Devin B. Sokol, Kyle K. Rasmussen, Todd E. TI USE OF RESUSCITATIVE ENDOVASCULAR BALLOON OCCLUSION OF THE AORTA IN A HIGHLY LETHAL MODEL OF NONCOMPRESSIBLE TORSO HEMORRHAGE SO SHOCK LA English DT Article DE Resuscitative endovascular balloon occlusion of the aorta; REBOA; noncompressible torso hemorrhage; hemorrhagic shock; resuscitation ID EMERGENCY-DEPARTMENT THORACOTOMY; ABDOMINAL-TRAUMA; SWINE MODEL; INJURY; SHOCK; DEATHS; MORTALITY; ANEURYSMS; ACID; CARE AB Noncompressible torso hemorrhage is a leading cause of death in trauma, with many patients dying before definitive hemorrhage control. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an adjunct than can be used to expand the window of salvage in patients with end-stage hemorrhagic shock. The aim of this study was to evaluate the effect of continuous and intermittent REBOA (iREBOA) on mortality using a highly lethal porcine model of noncompressible torso hemorrhage. Male splenectomized pigs (70-90 kg) underwent a laparoscopic liver injury (80% resection of left lobe) followed by a 10-min free-bleed period. Animals were then divided into three groups (n = 8) for a 60-min intervention phase (n = 8): continuous occlusion (cREBOA), iREBOA, or no occlusion (nREBOA). Groups then underwent whole blood resuscitation, damage control surgery, and further critical care. Endpoints were mortality and hemodynamic and circulating measures of shock and resuscitation. Systolic blood pressure (in mmHg) at the end of the free-bleed period for cREBOA, iREBOA, and nREBOA was 31 +/- 14, 48 +/- 28, and 28 +/- 17, respectively (P = 0.125). Following the start of the intervention phase, systolic blood pressure was higher in the iREBOA and cREBOA groups compared with the nREBOA (85 +/- 37 and 96 +/- 20 vs. 42 +/- 4; P < 0.001). Overall mortality for the cREBOA, iREBOA, and nREBOA groups was 25.0%, 37.5%, and 100.0% (P = 0.001). Resuscitative endovascular balloon occlusion of the aorta can temporize exsanguinating hemorrhage and restore life-sustaining perfusion, bridging critical physiology to definitive hemorrhage control. Prospective observational studies of REBOA as a hemorrhage control adjunct should be undertaken in appropriate groups of human trauma patients. C1 [Morrison, Jonathan J.] Royal Ctr Def Med, Acad Dept Mil Surg & Trauma, Birmingham, W Midlands, England. [Morrison, Jonathan J.] Glasgow Royal Infirm, Acad Surg Unit, Glasgow G4 0SF, Lanark, Scotland. [Morrison, Jonathan J.; Houston, Robert; Watson, Devin B.; Sokol, Kyle K.; Rasmussen, Todd E.] US Army Inst Surg Res, Ft Sam Houston, TX USA. [Ross, James D.; Sokol, Kyle K.; Rasmussen, Todd E.] 59th Med Wing, Lackland AFB, TX USA. [Houston, Robert; Watson, Devin B.; Rasmussen, Todd E.] San Antonio Mil Med Ctr, Dept Surg, Ft Sam Houston, TX USA. [Rasmussen, Todd E.] Uniformed Serv Univ Hlth Sci, Norman M Rich Dept Surg, Bethesda, MD 20814 USA. RP Rasmussen, TE (reprint author), USAF MC, US Combat Casualty Care Res Program, 722 Doughten St,Room 3, Ft Detrick, MD 21702 USA. EM todd.e.rasmussen.mil@mail.mil OI Morrison, Jonathan/0000-0001-7462-8456 FU US Air Force FX Funding was received from the US Air Force. NR 32 TC 24 Z9 24 U1 0 U2 4 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 1073-2322 EI 1540-0514 J9 SHOCK JI Shock PD FEB PY 2014 VL 41 IS 2 BP 130 EP 137 DI 10.1097/SHK.0000000000000085 PG 8 WC Critical Care Medicine; Hematology; Surgery; Peripheral Vascular Disease SC General & Internal Medicine; Hematology; Surgery; Cardiovascular System & Cardiology GA AH5ZI UT WOS:000336209800008 PM 24430492 ER PT J AU Prunet, B Prat, N Couret, D Cordier, PY De Bourmont, S Lambert, D Asencio, Y Meaudre, E Michelet, P AF Prunet, Bertrand Prat, Nicolas Couret, David Cordier, Pierre-Yves De Bourmont, Sophie Lambert, Dominique Asencio, Yves Meaudre, Eric Michelet, Pierre TI MIDTERM EFFECTS OF FLUID RESUSCITATION STRATEGIES IN AN EXPERIMENTAL MODEL OF LUNG CONTUSION AND HEMORRHAGIC SHOCK SO SHOCK LA English DT Article DE Lung contusion; blunt chest trauma; hemorrhagic shock; fluid resuscitation; hypertonic saline; pulmonary edema; extravascular lung water ID BLUNT CHEST TRAUMA; EXPERIMENTAL PULMONARY CONTUSION; HYDROXYETHYL STARCH; PORCINE MODEL; HYPERTONIC SALINE; COMBAT CASUALTIES; RINGERS ACETATE; SEVERE SEPSIS; INJURY; MANAGEMENT AB Background: This study compared three different fluid resuscitation strategies in terms of respiratory tolerance and hemodynamic efficacy in a pig model of blunt chest trauma with lung contusion and controlled hemorrhagic shock. We hypothesized that the choice of fluid resuscitation strategy (type and amount of fluids) may impact differently contused lungs in terms of extravascular lung water (EVLW) 20 h after trauma. Methods: Anesthetized female pigs (n = 5/group) received five bolt shots to the right thoracic cage and allowed to hemorrhage for 30 min, with 25 to 30 mL/kg of blood loss. Pigs were randomly assigned to resuscitation groups that maintained a minimum mean arterial blood pressure of 70 mmHg with one of three methods: normal saline (NS), unrestricted normal saline; NOREPI, low-volume normal saline with norepinephrine; or HS-HES, hypertonic saline with hydroxyethyl starch. Control pigs were anesthetized, but received no injury or treatment. After 20 h, animals were killed to measure EVLW by gravimetry. Results: Fluid loading was significantly different in each group. All three treatment groups had higher EVLW than controls. Moderate, bilateral pulmonary edema was observed in the NS and HS-HES groups. The three treatment groups showed similar reductions in oxygenation. Static pulmonary compliance was diminished in the NS and HS-HES groups, but compliance was similar in NOREPI and control groups. The NOREPI group had pathological lactate levels. Conclusions: This study demonstrated the impact of fluid resuscitation on contused lungs. Twenty hours after the trauma, all three resuscitation approaches showed modest clinical consequences, with moderate lung edema and reduced compliance in response to the infused volume. C1 [Prunet, Bertrand; Meaudre, Eric] St Anne Mil Teaching Hosp, Intens Care Unit, Toulon, France. [Prunet, Bertrand; Couret, David; De Bourmont, Sophie; Michelet, Pierre] Univ Aix Marseille, Sch Med, P2COE, UMR MD2, Marseille, France. [Prat, Nicolas] US Army Inst Surg Res, Ft Sam Houston, TX USA. [Couret, David; De Bourmont, Sophie; Lambert, Dominique; Michelet, Pierre] Timone Univ Hosp, Dept Emergency Med & Intens Care, Marseille, France. [Cordier, Pierre-Yves] Laveran Mil Teaching Hosp, Intens Care Unit, Bordeaux, France. [Asencio, Yves] Pique Mil Teaching Hosp, Dept Anesthesiol, Bordeaux, France. RP Prunet, B (reprint author), Hop Instruct Armees St Anne, Serv Reanimat, St Anne Blvd, F-83000 Toulon, France. EM bertrand.prunet@orange.fr RI PRAT, Nicolas/R-4213-2016 FU UMR (University of Aix-Marseille) [MD2 P2COE]; French Army Institute of Biomedical Research FX This study was supported by institutional funds from UMR MD2 P2COE (University of Aix-Marseille) and French Army Institute of Biomedical Research. NR 38 TC 6 Z9 6 U1 2 U2 4 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 1073-2322 EI 1540-0514 J9 SHOCK JI Shock PD FEB PY 2014 VL 41 IS 2 BP 159 EP 165 DI 10.1097/SHK.0000000000000069 PG 7 WC Critical Care Medicine; Hematology; Surgery; Peripheral Vascular Disease SC General & Internal Medicine; Hematology; Surgery; Cardiovascular System & Cardiology GA AH5ZI UT WOS:000336209800012 PM 24434419 ER PT J AU Subramanian, V Semenzin, E Hristozov, D Marcomini, A Linkov, I AF Subramanian, Vrishali Semenzin, Elena Hristozov, Danail Marcomini, Antonio Linkov, Igor TI Sustainable nanotechnology: Defining, measuring and teaching SO NANO TODAY LA English DT Article DE Sustainability; Nanotechnology; Risk assessment; Decision analysis; Nanomanufacturing; Education AB The complexity of nanomaterials themselves as well as the enabling nature of nanotechnology in general results in significant difficulties in defining and measuring sustainability associated with emerging materials and products. Defining metrics of environmental, societal, and economic impacts and integrating them into a multi-criteria decision analysis model is one way to assess the sustainability of nanoproducts and processes through an application-focused top-down approach. Given the current high level of uncertainty in many aspects of nanotechnology and the unknown trajectory of a field still in its infancy, it is important to teach nanotechnology in a contextual setting where discussions of uncertainty and variability are strongly encouraged. Sustainability should be linked to technology management processes to capture evolving technology and understanding of its benefits and risks. Published by Elsevier Ltd. C1 [Subramanian, Vrishali; Semenzin, Elena; Hristozov, Danail; Marcomini, Antonio; Linkov, Igor] Ca Foscari Univ Venice, Dept Environm Sci Informat & Stat, Venice, Italy. [Linkov, Igor] US Army Engineer, Ctr Res & Dev, Concord, MA 01742 USA. RP Linkov, I (reprint author), US Army Engineer, Ctr Res & Dev, 696 Virginia Rd, Concord, MA 01742 USA. EM lgor.Linkov@usace.army.mil OI Hristozov, Danail/0000-0002-2386-7366 NR 11 TC 5 Z9 9 U1 0 U2 14 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 1748-0132 EI 1878-044X J9 NANO TODAY JI Nano Today PD FEB PY 2014 VL 9 IS 1 BP 6 EP 9 DI 10.1016/j.nantod.2014.01.001 PG 4 WC Chemistry, Multidisciplinary; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Chemistry; Science & Technology - Other Topics; Materials Science GA AG7VS UT WOS:000335627500005 ER PT J AU Henemyre-Harris, CL Samols, M Wenick, AS Sokoll, LJ AF Henemyre-Harris, Claudia L. Samols, Mark Wenick, Adam S. Sokoll, Lori J. TI Glow Stick or Urine Sample? SO CLINICAL CHEMISTRY LA English DT Editorial Material ID CLINICAL LABORATORY TESTS; FLUORESCEIN INTERFERENCE C1 [Henemyre-Harris, Claudia L.; Samols, Mark; Sokoll, Lori J.] Johns Hopkins Med Inst, Dept Pathol, Baltimore, MD 21287 USA. [Henemyre-Harris, Claudia L.] US Army Med Dept Ctr & Sch, Ft Sam Houston, TX USA. [Wenick, Adam S.] Johns Hopkins Med Inst, Wilmer Eye Inst, Baltimore, MD 21287 USA. RP Sokoll, LJ (reprint author), Johns Hopkins Med Inst, Dept Pathol, 1800 Orleans St,Zayed Tower B1020K, Baltimore, MD 21287 USA. EM lsokoll@jhmi.edu NR 5 TC 0 Z9 0 U1 0 U2 0 PU AMER ASSOC CLINICAL CHEMISTRY PI WASHINGTON PA 2101 L STREET NW, SUITE 202, WASHINGTON, DC 20037-1526 USA SN 0009-9147 EI 1530-8561 J9 CLIN CHEM JI Clin. Chem. PD FEB PY 2014 VL 60 IS 2 BP 425 EP 426 DI 10.1373/clinchem.2013.205013 PG 2 WC Medical Laboratory Technology SC Medical Laboratory Technology GA AG1AD UT WOS:000335146300025 PM 24474733 ER PT J AU Centeno, JA Rogers, DA van der Voet, GB Fornero, E Zhang, LS Mullick, FG Chapman, GD Olabisi, AO Wagner, DJ Stojadinovic, A Potter, BK AF Centeno, Jose A. Rogers, Duane A. van der Voet, Gijsbert B. Fornero, Elisa Zhang, Lingsu Mullick, Florabel G. Chapman, Gail D. Olabisi, Ayodele O. Wagner, Dean J. Stojadinovic, Alexander Potter, Benjamin K. TI Embedded Fragments from US Military Personnel-Chemical Analysis and Potential Health Implications SO INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH LA English DT Article DE metal-fragments; depleted-uranium (DU); tungsten; heavy metal tungsten-alloys (HMTA); lead (Pb); improvised-explosive device (IED); explosively-formed projectile (EFP); X-ray fluorescence spectrometry (XRF); inductively-coupled-plasma mass-spectrometry (ICP-MS); confocal laser Raman-microspectroscopy (CLRM); scanning-electron-microscopy energy-dispersive X-ray analysis (SEM-EDXA); elemental analysis ID METAL-TUNGSTEN-ALLOY; BROKEN CERCLAGE WIRE; DEPLETED URANIUM; MASS-SPECTROMETRY; GENE-EXPRESSION; WOUNDS; WAR; MANAGEMENT; MIGRATION; INJURY AB Background: The majority of modern war wounds are characterized by high-energy blast injuries containing a wide range of retained foreign materials of a metallic or composite nature. Health effects of retained fragments range from local or systemic toxicities to foreign body reactions or malignancies, and dependent on the chemical composition and corrosiveness of the fragments in vivo. Information obtained by chemical analysis of excised fragments can be used to guide clinical decisions regarding the need for fragment removal, to develop therapeutic interventions, and to better anticipate future medical problems from retained fragment related injuries. In response to this need, a new U. S Department of Defense (DoD) directive has been issued requiring characterization of all removed fragments to provide a database of fragment types occurring in combat injuries. Objectives: The objective of this study is to determine the chemical composition of retained embedded fragments removed from injured military personnel, and to relate results to histological findings in tissue adjacent to fragment material. Methods: We describe an approach for the chemical analysis and characterization of retained fragments and adjacent tissues, and include case examples describing fragments containing depleted uranium (DU), tungsten (W), lead (Pb), and non-metal foreign bodies composed of natural and composite materials. Fragments obtained from four patients with penetrating blast wounds to the limbs were studied employing a wide range of chemical and microscopy techniques. Available adjacent tissues from three of the cases were histologically, microscopically, and chemically examined. The physical and compositional properties of the removed foreign material surfaces were examined with energy dispersive x-ray fluorescence spectrometry (EDXRF), scanning electron microscopy (SEM), laser ablation inductively-coupled plasma mass-spectrometry (LA-ICP-MS), and confocal laser Raman microspectroscopy (CLRM). Quantitative chemical analysis of both fragments and available tissues was conducted employing ICP-MS. Results: Over 800 fragments have been characterized and included as part of the Joint Pathology Center Embedded Fragment Registry. Most fragments were obtained from penetrating wounds sustained to the extremities, particularly soft tissue injuries. The majority of the fragments were primarily composed of a single metal such as iron, copper, or aluminum with traces of antimony, titanium, uranium, and lead. One case demonstrated tungsten in both the fragment and the connected tissue, together with lead. Capsular tissue and fragments from a case from the 1991 Kuwait conflict showed evidence of uranium that was further characterized by uranium isotopic ratios analysis to contain depleted uranium. Conclusions: The present study provides a systematic approach for obtaining a full chemical characterization of retained embedded fragments. Given the vast number of combat casualties with retained fragments, it is expected that fragment analysis will have significant implications for the optimal short and long-term care of wounded service members. C1 [Centeno, Jose A.; Rogers, Duane A.; van der Voet, Gijsbert B.; Fornero, Elisa; Zhang, Lingsu; Mullick, Florabel G.] Joint Pathol Ctr, Div Biophys Toxicol, Silver Spring, MD 20910 USA. [Chapman, Gail D.; Olabisi, Ayodele O.; Wagner, Dean J.] Naval Med Res Unit Dayton, Wright Patterson AFB, OH 45433 USA. [Stojadinovic, Alexander] Walter Reed Army Med Ctr, Combat Wound Initiat Program, Washington, DC 20307 USA. [Potter, Benjamin K.] Walter Reed Army Med Ctr, Integrated Dept Orthopaed & Rehabil, Washington, DC 20307 USA. RP Centeno, JA (reprint author), Joint Pathol Ctr, Div Biophys Toxicol, Silver Spring, MD 20910 USA. EM jose.a.centeno@us.army.mil; duane.rogers@afncr.af.mil; b.v.d.voet@gr.nl; elisa.fornero@gmail.com; lingsu.zhang@usda.gov; florabel.g.mullick.ctr@mail.mil; gail.chapman@med.navy.mil; ayodele.olabisi@dtra.mil; dean.wagner@med.navy.mil; alexander.stojadinovic@us.army.mil; Benjamin.k.potter.mil@health.mil OI Potter, MD, Benjamin K./0000-0002-8771-0317 FU U.S. Navy; Naval Health Research Center-Environmental Health Effects Laboratory [ISSA 9780130]; Defense Health Program Work Unit [60665] FX This effort was supported in part by the U.S. Navy and the Naval Health Research Center-Environmental Health Effects Laboratory (ISSA 9780130), Defense Health Program Work Unit 60665. NR 32 TC 8 Z9 8 U1 2 U2 15 PU MDPI AG PI BASEL PA POSTFACH, CH-4005 BASEL, SWITZERLAND SN 1660-4601 J9 INT J ENV RES PUB HE JI Int. J. Environ. Res. Public Health PD FEB PY 2014 VL 11 IS 2 BP 1261 EP 1278 DI 10.3390/ijerph110201261 PG 18 WC Environmental Sciences; Public, Environmental & Occupational Health SC Environmental Sciences & Ecology; Public, Environmental & Occupational Health GA AF0WZ UT WOS:000334436600005 PM 24464236 ER PT J AU Seay, JF Frykman, PN Sauer, SG Gutekunst, DJ AF Seay, Joseph F. Frykman, Peter N. Sauer, Shane G. Gutekunst, David J. TI Lower Extremity Mechanics During Marching at Three Different Cadences for 60 Minutes SO JOURNAL OF APPLIED BIOMECHANICS LA English DT Article DE walking gait; joint moments; ground reaction forces; joint powers; step rate ID TIBIAL STRESS-FRACTURE; FEMALE ARMY TRAINEES; RISK-FACTORS; STRIDE LENGTHS; INJURY RATES; WALKING; RECRUITS; GAIT; ABSORPTION; RUNNERS AB During group marches, soldiers must walk in step with one another at the same imposed cadence. The literature suggests that shorter trainees may be more susceptible to injury due to overstriding that can occur when taller recruits dictate marching cadence. This study assessed the effects of fixed cadence simulated marching at cadences above and below preferred step rate (PSR) on lower extremity joint mechanics in individuals who were unaccustomed to marching. During three separate visits, 13 volunteers walked with a 20 kg load on a force-sensing treadmill at self-selected PSR, PSR+15% (shorter strides), and PSR-15% (longer strides) at 1.3 m/s for 60 mm. Two-way RM ANOVAs (cadence by time) were performed during the stance phase. Ranges of motion and anteroposterior ground reaction force increased significantly as cadence decreased (P < .03). Knee extension moment increased slightly when step rate decreased from PSR+15% (shortest strides, 0.85 +/- 0.2 N m/kg) to PSR (0.87 +/- 0.3 N m/kg, 3% increase); however, this increase was substantially greater (20% increase) when cadence was decreased from PSR to PSR-15% (longest strides, 1.09 +/- 0.3 N m/kg). Our results indicate that overstriding during fixed-cadence marching is a factor that can substantially increase mechanical stress on lower extremity joints. C1 [Seay, Joseph F.; Frykman, Peter N.; Sauer, Shane G.; Gutekunst, David J.] US Army, Environm Med Res Inst, Natick, MA 01760 USA. RP Seay, JF (reprint author), US Army, Environm Med Res Inst, Natick, MA 01760 USA. NR 29 TC 1 Z9 1 U1 1 U2 7 PU HUMAN KINETICS PUBL INC PI CHAMPAIGN PA 1607 N MARKET ST, PO BOX 5076, CHAMPAIGN, IL 61820-2200 USA SN 1065-8483 EI 1543-2688 J9 J APPL BIOMECH JI J. Appl. Biomech. PD FEB PY 2014 VL 30 IS 1 BP 21 EP 30 DI 10.1123/jab.2012-0090 PG 10 WC Engineering, Biomedical; Sport Sciences SC Engineering; Sport Sciences GA AF2RP UT WOS:000334560000003 PM 23549415 ER PT J AU Samy, RP Manikandan, J Sethi, G Franco, OL Okonkwo, JC Stiles, BG Chow, VTK Gopalakrishnakone, P Al Qahtani, M AF Samy, Ramar Perumal Manikandan, Jayapal Sethi, Gautam Franco, Octavio L. Okonkwo, Josiah C. Stiles, Bradley G. Chow, Vincent T. K. Gopalakrishnakone, Ponnampalam Al Qahtani, Mohammed TI Snake Venom Proteins: Development into Antimicrobial and Wound Healing Agents SO MINI-REVIEWS IN ORGANIC CHEMISTRY LA English DT Article DE Methicillin resistant Staphylococcus aureus (MRSA); snake venom protein; endogenous antibiotics; Lys49 & Asp49-PLA(2); inflammatory cytokines; growth factors; skin; wound healing; transcription factors NF-kB; Cys-rich protein ID AMINO-ACID OXIDASE; SECRETED PHOSPHOLIPASES A(2); MEMBRANE-DAMAGING ACTIVITY; ANGIOTENSIN-CONVERTING ENZYME; DURISSUS-TERRIFICUS VENOM; DISINTEGRIN-LIKE PROTEIN; MEDIATED CELL-ADHESION; C-TERMINAL REGION; BOTHROPS-ALTERNATUS; BIOLOGICAL-ACTIVITY AB Infectious diseases are a significant cause of morbidity and mortality worldwide, accounting for approximately 50% of all deaths in tropical countries and as much as 20% of deaths in the USA. The emergence of multi- drug resistant (MDR) strains makes the risk of these infections even more threatening and an important public health problem thereby increasing need of new agents for fighting pathogens. In this review, the remarkable antibacterial properties possessed by various snake venoms (Crotalide, Elapidae, and Viperidae families) were discussed and in particular phospholipase A(2)s ( PLA(2)s) that have emerged from various studies as potential in the last few years. Group IIA PLA2s are the most potent among the snake venom (sv) PLA2s against various types of bacteria. Further, antibacterial derivatives from PLA2s, e. g. peptides derived from the C- terminal sequence of Lys49- PLA2s (amino acids 115- 129), kill bacteria and cause severe membrane- damaging effects. Mechanisms of binding to the bacterial surface and subsequent killing by peptides are based on positive charge, hydrophobicity, and length. These peptide candidates are easy to design and synthesize in pure form (similar to 95% purity). Such peptides may be potentially useful in the clinic as new antimicrobials for combating infections due to antibiotic- resistant bacteria that include methicillin- resistant Staphylococcus aureus (MRSA) and vancomycin- resistant Enterococcus in the near future. C1 [Samy, Ramar Perumal; Chow, Vincent T. K.] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Microbiol, Infectious Dis Programme, Singapore 117597, Singapore. [Samy, Ramar Perumal; Gopalakrishnakone, Ponnampalam] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Anat, Venom & Toxin Res Programme, Singapore 117597, Singapore. [Manikandan, Jayapal; Al Qahtani, Mohammed] King Abdulaziz Univ, Ctr Excellence Genom Med Res, Jeddah 21589, Saudi Arabia. [Sethi, Gautam] Natl Univ Singapore, Yong Loo Lin Sch Med, Clin Res Ctr, Dept Pharmacol,NUHS, Singapore 117597, Singapore. [Franco, Octavio L.] Univ Catolica Brasilia, Ctr Anal Prot & Bioquim, Posgrad Ciencias Genom & Biotecnol, Brasilia, DF, Brazil. [Stiles, Bradley G.] Nnamdi Azikiwe Univ, Dept Anim Sci & Technol, Anambra, Nigeria. [Stiles, Bradley G.] US Army, Med Res Inst Infect Dis, Integrated Toxicol Div, Ft Detrick, MD 21702 USA. [Stiles, Bradley G.] Wilson Coll, Dept Biol, Chambersburg, PA 17201 USA. RP Samy, RP (reprint author), Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Anat, Venom & Toxin Res Programme, Singapore 117597, Singapore. EM rperumalsamy@yahoo.co.uk FU Defence Science and Technology Agency (DSTA), Singapore [R - 181 000 063 422] FX This work was supported by the Defence Science and Technology Agency (DSTA), Singapore for financial support (Grant R - 181 000 063 422). NR 108 TC 0 Z9 0 U1 4 U2 8 PU BENTHAM SCIENCE PUBL LTD PI SHARJAH PA EXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES SN 1570-193X EI 1875-6298 J9 MINI-REV ORG CHEM JI Mini-Rev. Org. Chem. PD FEB PY 2014 VL 11 IS 1 BP 4 EP 14 PG 11 WC Chemistry, Organic SC Chemistry GA AE9UV UT WOS:000334357200002 ER PT J AU Klapotke, TM Piercey, DG Mehta, N Oyler, KD Sabatini, JJ AF Klapoetke, Thomas M. Piercey, Davin G. Mehta, Neha Oyler, Karl D. Sabatini, Jesse J. TI Reaction of Copper(I) Nitrotetrazolate (DBX-1) with Sodium m-Periodate (vol 69, pg 125, 2014) SO ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES LA English DT Correction C1 [Klapoetke, Thomas M.; Piercey, Davin G.] Univ Munich, Dept Chem, D-81377 Munich, Germany. [Mehta, Neha; Oyler, Karl D.] US Army RDECOM ARDEC, Explos Dev Branch, Picatinny Arsenal, NJ 07806 USA. [Sabatini, Jesse J.] US Army RDECOM ARDEC, Pyrotech Technol & Prototyping Div, Picatinny Arsenal, NJ 07806 USA. RP Klapotke, TM (reprint author), Univ Munich, Dept Chem, Butenandtstr 5-13, D-81377 Munich, Germany. RI Klapoetke, Thomas/B-6055-2014 OI Klapoetke, Thomas/0000-0003-3276-1157 NR 1 TC 0 Z9 0 U1 0 U2 7 PU VERLAG Z NATURFORSCH PI TUBINGEN PA POSTFACH 2645, 72016 TUBINGEN, GERMANY SN 0932-0776 EI 1865-7117 J9 Z NATURFORSCH B JI Z.Naturforsch.(B) PD FEB PY 2014 VL 69 IS 2 BP 275 EP 275 PG 1 WC Chemistry, Inorganic & Nuclear; Chemistry, Organic SC Chemistry GA AE8PU UT WOS:000334264600019 ER PT J AU O'Connor, V Deutsch, GB Arena, EA Albright, J O'Connor, RP Sim, M Bilchik, A Ellenhorn, JD AF O'Connor, V. Deutsch, G. B. Arena, E. A. Albright, J. O'Connor, R. P. Sim, M. Bilchik, A. Ellenhorn, J. D. TI A Decade of Experience with Postoperative Imatinib Mesylate for Gastrointestinal Stromal Tumors: Does the Duration of Treatment Increase Long-term Survival? SO ANNALS OF SURGICAL ONCOLOGY LA English DT Meeting Abstract CT 67th Annual Cancer Symposium of the Society-of-Surgical-Oncology CY MAR 12-15, 2014 CL Phoenix, AZ SP Soc Surg Oncol C1 [O'Connor, V.; Deutsch, G. B.; Arena, E. A.; Albright, J.; Sim, M.; Bilchik, A.; Ellenhorn, J. D.] John Wayne Canc Inst, Santa Monica, CA USA. [O'Connor, R. P.] US Army Reserve, Los Angeles, CA USA. NR 0 TC 0 Z9 0 U1 1 U2 1 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1068-9265 EI 1534-4681 J9 ANN SURG ONCOL JI Ann. Surg. Oncol. PD FEB PY 2014 VL 21 SU 1 BP S29 EP S30 PG 2 WC Oncology; Surgery SC Oncology; Surgery GA AE7WC UT WOS:000334209100070 ER PT J AU Rao, SS Prater, JT Wu, F Nori, S Kumar, D Narayan, J AF Rao, S. S. Prater, J. T. Wu, Fan Nori, Sudhakar Kumar, D. Narayan, J. TI Integration of epitaxial permalloy on Si (100) through domain matching epitaxy paradigm SO CURRENT OPINION IN SOLID STATE & MATERIALS SCIENCE LA English DT Review DE Permalloy; Pulsed laser deposition; Coercive field; Exchange bias; Domain matching epitaxy ID THIN-FILMS; DEPOSITION; ANISOTROPY; GROWTH; MGO; HETEROSTRUCTURES; INTERFACES; SENSORS; FEPT AB This paper addresses epitaxial integration of magnetic materials with Si (1 0 0) based solid state devices. Epitaxial Ni82.5Fe17.5 (permalloy, Py) thin films have been synthesized by pulsed laser deposition (PLD) on Si (1 0 0) using MgO/TiN as a template buffer. This epitaxial growth of these large lattice misfit systems was achieved through domain matching epitaxy (DME). The in-plane XRD pattern and selective area electron diffraction (SAED) results clearly indicate cube-on-cube epitaxial alignment. The bright field TEM image of Py/MgO/TiN/Si (1 0 0) heterostructure infers a Py layer thickness of similar to 30 nm, with a well aligned island (150-200 nm) structure that is consistent with Volmer-Weber type growth. Magnetization data collected at 4 K and 300 K indicates that the easy axis of the magnetization lies in the plane of the Py. In addition, we have observed an intrinsic positive exchange bias (PEB) field of similar to 104 Oe, where the magnetic hysteresis loop is shifted toward the positive field axis under zero field cooling conditions. (C) 2013 Elsevier Ltd. All rights reserved. C1 [Rao, S. S.; Prater, J. T.] US Army, Res Off, Div Mat Sci, Res Triangle Pk, NC 27709 USA. [Rao, S. S.; Prater, J. T.; Wu, Fan; Nori, Sudhakar; Narayan, J.] N Carolina State Univ, Dept Mat Sci & Engn, Raleigh, NC 27695 USA. [Kumar, D.] N Carolina Agr & Tech State Univ, Ctr Adv Mat, Greensboro, NC 27411 USA. RP Rao, SS (reprint author), N Carolina State Univ, Dept Mat Sci & Engn, Box 7907, Raleigh, NC 27695 USA. EM ssingam@ncsu.edu RI Nori, Sudhakar/E-8111-2010 FU National Academy of Science (NAS), USA; Army Research Office [W911NF-04-D-0003] FX SSR acknowledges National Academy of Science (NAS), USA for awarding the NRC postdoctoral research associate fellowship. The authors gratefully acknowledge Jerome Cuomo for loaning us permalloy target. We thank C.T. Shelton and J.-P. Maria for their valuable help in phi-scan XRD. The authors are pleased to acknowledge the support of the Army Research Office under Grant W911NF-04-D-0003. NR 33 TC 4 Z9 4 U1 7 U2 43 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 1359-0286 EI 1879-0348 J9 CURR OPIN SOLID ST M JI Curr. Opin. Solid State Mat. Sci. PD FEB PY 2014 VL 18 IS 1 SI SI BP 1 EP 5 DI 10.1016/j.cossms.2013.07.004 PG 5 WC Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter SC Materials Science; Physics GA AE3EH UT WOS:000333859300001 ER PT J AU Liu, H Kim, Y Mello, K Lovaasen, J Shah, A Rice, N Yim, JH Pappas, D Klibanov, AM AF Liu, Harris Kim, Yoojeong Mello, Kerrianne Lovaasen, John Shah, Apoorva Rice, Norman Yim, Jacqueline H. Pappas, Daphne Klibanov, Alexander M. TI Aerosol-Assisted Plasma Deposition of Hydrophobic Polycations Makes Surfaces Highly Antimicrobial SO APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY LA English DT Article DE N-alkylated polyethylenimine; Immobilization by aerosol-assisted plasma deposition; Microbicidal coatings; Antibacterial; Antiviral ID COATINGS AB The currently used multistep chemical synthesis for making surfaces antimicrobial by attaching to them hydrophobic polycations is replaced herein by an aerosol-assisted plasma deposition procedure. To this end, N,N-hexyl,methyl-PEI (HMPEI) is directly plasma-coated onto a glass surface. The resultant immobilized HMPEI coating has been thoroughly characterized and shown to be robust, bactericidal against Escherichia coli, and virucidal against human influenza virus. C1 [Liu, Harris; Klibanov, Alexander M.] MIT, Dept Chem, Cambridge, MA 02139 USA. [Klibanov, Alexander M.] MIT, Dept Biol Engn, Cambridge, MA 02139 USA. [Kim, Yoojeong; Mello, Kerrianne; Shah, Apoorva; Rice, Norman] Triton Syst Inc, Chelmsford, MA 01824 USA. [Yim, Jacqueline H.; Pappas, Daphne] US Army Res Lab, Multifunct Mat Branch, Weap & Mat Res Directorate, Aberdeen, MD 21005 USA. [Lovaasen, John] Triton Syst Inc, Fargo, ND 58102 USA. RP Klibanov, AM (reprint author), MIT, Dept Chem, 77 Massachusetts Ave, Cambridge, MA 02139 USA. EM klibanov@mit.edu FU US Army Research Office [W911NF-07-D-0004] FX This research was financially supported by the US Army Research Office under contract W911NF-07-D-0004. NR 15 TC 1 Z9 1 U1 1 U2 20 PU HUMANA PRESS INC PI TOTOWA PA 999 RIVERVIEW DRIVE SUITE 208, TOTOWA, NJ 07512 USA SN 0273-2289 EI 1559-0291 J9 APPL BIOCHEM BIOTECH JI Appl. Biochem. Biotechnol. PD FEB PY 2014 VL 172 IS 3 BP 1254 EP 1264 DI 10.1007/s12010-013-0593-4 PG 11 WC Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology SC Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology GA AD4UL UT WOS:000333246400009 PM 24158590 ER PT J AU Knapik, JJ Steelman, R Hoedebecke, K Klug, KL Rankin, S Proctor, S Graham, B Jones, BH AF Knapik, Joseph J. Steelman, Ryan Hoedebecke, Kyle Klug, Kevin L. Rankin, Shawn Proctor, Stanley Graham, Bria Jones, Bruce H. TI Risk Factors for Closed-Head Injuries During Military Airborne Operations SO AVIATION SPACE AND ENVIRONMENTAL MEDICINE LA English DT Article DE wind speed; night; combat loads; temperature; aircraft; entanglements; T-10D parachute ID TYPICAL PARACHUTE INJURIES; TRAUMATIC BRAIN-INJURY; CONCUSSION; JUMPS; SURVEILLANCE; SYSTEM; HELMET; COHORT; SCHOOL; SPORT AB Introduction: One of the more serious adverse outcomes of military airborne operations is closed-head injuries. This investigation examined risk factors for closed-head injuries in an Army airborne infantry unit. Methods: Closed-head injuries were defined as energy exchanges in which the head contacted the ground or an object and the soldier sought medical care for external trauma, headache, loss of consciousness, or altered mental state. Injury data were obtained by investigators in the drop zone and diagnoses were confirmed by a physician. Operational data on potential injury risk factors were obtained from routine reports published by the infantry unit. Weather data were obtained using a pocket weather tracker. Results: There were 96,132 jumps resulting in 310 closed-head injuries for a crude incidence of 3.22/1000 jumps. In 98% of known cases the injury was associated with parachute landings. Multivariate logistic regression revealed that independent risk factors for closed-head injuries included night jumps, combat loads, higher wind speeds, higher temperatures, enlisted rank, and entanglements. Conclusions: This study identifies the current incidence and extrinsic risk factors for closed-head injuries during military airborne operations. Although it is necessary to conduct airborne training under realistic conditions, trainers and commanders should be aware of these risks and plan airborne operations accordingly. C1 US Army, Inst Publ Hlth, Aberdeen Proving Ground, MD 21010 USA. Womack Army Med Ctr, Ft Bragg, NC USA. Concurrent Technol Corp, Fayetteville, NC USA. Johns Hopkins Univ Hosp, Baltimore, MD 21287 USA. RP Knapik, JJ (reprint author), US Army, Inst Publ Hlth, ATTN MCHB IPDI, Aberdeen Proving Ground, MD 21010 USA. EM joseph.knapik@us.army.mil FU Defense Safety Oversight Council; Office of the Assistant Secretary of the Army (Installations, Energy and Environment); U.S. Army Public Health Command (USAPHC); [W74V8H-04-D-0005] FX For their assistance with this investigation we would like to thank Mr. Tyson Grier, LTC Robert Malsby, LTC Michael Sassano, COL Michael Smith, Dr. Ellen Segan, Mr. Tommy Brown, Mr. Earl Jefferson, CPT King Cooper, MSG Todd Winhoven, CW4 Thompson, CW3 Lewis, Mr. Nick Weidler, Mr. Terence (Sean) Hensey, and Mr Keith Colliver. Mr. Shane Hall served as our statistical consultant. This work was funded through the Defense Safety Oversight Council and the Office of the Assistant Secretary of the Army (Installations, Energy and Environment) and conducted under contract W74V8H-04-D-0005 Task 0517. This work was also supported in part by an appointment to the Knowledge Preservation Program at the U.S. Army Public Health Command (USAPHC) administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the U.S. Department of Energy and USAPHC. NR 31 TC 4 Z9 4 U1 0 U2 3 PU AEROSPACE MEDICAL ASSOC PI ALEXANDRIA PA 320 S HENRY ST, ALEXANDRIA, VA 22314-3579 USA SN 0095-6562 EI 1943-4448 J9 AVIAT SPACE ENVIR MD JI Aviat. Space Environ. Med. PD FEB PY 2014 VL 85 IS 2 BP 105 EP 111 DI 10.3357/ASEM.3788.2014 PG 7 WC Public, Environmental & Occupational Health; Medicine, General & Internal; Sport Sciences SC Public, Environmental & Occupational Health; General & Internal Medicine; Sport Sciences GA AD1MB UT WOS:000332997000001 PM 24597153 ER PT J AU Kelley, AM Grandizio, CM Estrada, A Crowley, JS AF Kelley, Amanda M. Grandizio, Catherine M. Estrada, Arthur Crowley, John S. TI Tactile Cues in Continuous Operations: A Preliminary Study SO AVIATION SPACE AND ENVIRONMENTAL MEDICINE LA English DT Article DE tactile cuing; habituation; adaptation AB Introduction: Research has shown that tactile displays are an effective tool for augmenting spatial orientation and situation awareness information provided to aircraft operators. The tactile situation awareness system (TSAS) has been shown to improve flight performance in conditions of degraded visual environments and to safely maintain performance during hover over moving targets. The potential for the user to adapt and habituate to the stimulus of tactile display systems has not yet been investigated. Methods: Four UH-60 current, rated aviators (all male) participated in the pilot study. Subjects completed four consecutive iterations of a 3-h flight profile consisting of 10 maneuvers, totaling 12 h of continuous flight. Flight performance, tactor information, responses to a discomfort questionnaire, and ratings of fatigue symptoms were recorded. Results: The independent variable in all analyses was session (four levels). The results showed that performance per maneuver and proportion of stimulus cues (measure of response to cues) per maneuver were consistent across sessions using independent-samples Kruskal-Wallis tests. Discussion: The findings of this preliminary assessment support the use of tactile displays (consistent with parameters of TSAS) in continuous operations since performance and proportion of stimulus cues presented was consistent over a period of 12 h. In conclusion, the system will require further experimental testing, but these preliminary findings do not suggest performance or response to be affected by any adaptation or habituation to the stimulus. C1 [Kelley, Amanda M.; Crowley, John S.] US Army Aeromed Res Lab, Warfighter Hlth Div, Ft Rucker, AL USA. RP Kelley, AM (reprint author), Natl Highway Traff Safety Adm US, Off Behav Safety Res, West Bldg 46-495,1200 New Jersey Ave SE,NTI 132, Washington, DC 20590 USA. EM akelley1981@gmail.com FU U.S. Army Medical Research and Materiel Command's Military Operational Medicine Research Program FX The authors would like to acknowledge the dedication and professionalism of the research staff of the Warfighter Health Division and Flight Systems Branch, U.S. Army Aeromedical Research Laboratory, for their contributions to the success of this project. This study was funded by the U.S. Army Medical Research and Materiel Command's Military Operational Medicine Research Program. NR 7 TC 1 Z9 1 U1 1 U2 3 PU AEROSPACE MEDICAL ASSOC PI ALEXANDRIA PA 320 S HENRY ST, ALEXANDRIA, VA 22314-3579 USA SN 0095-6562 EI 1943-4448 J9 AVIAT SPACE ENVIR MD JI Aviat. Space Environ. Med. PD FEB PY 2014 VL 85 IS 2 BP 172 EP 176 DI 10.3357/ASEM.3737.2014 PG 5 WC Public, Environmental & Occupational Health; Medicine, General & Internal; Sport Sciences SC Public, Environmental & Occupational Health; General & Internal Medicine; Sport Sciences GA AD1MB UT WOS:000332997000010 PM 24597162 ER PT J AU Minogue, TD Rachwal, PA Hall, AT Koehler, JW Weller, SA AF Minogue, Timothy D. Rachwal, Phillip A. Hall, Adrienne Trombley Koehler, Jeffery W. Weller, Simon A. TI Cross-Institute Evaluations of Inhibitor-Resistant PCR Reagents for Direct Testing of Aerosol and Blood Samples Containing Biological Warfare Agent DNA SO APPLIED AND ENVIRONMENTAL MICROBIOLOGY LA English DT Article ID REAL-TIME PCR; POLYMERASE CHAIN-REACTION; SMART CYCLER PLATFORMS; BACILLUS-ANTHRACIS; YERSINIA-PESTIS; FRANCISELLA-TULARENSIS; AMPLIFICATION; VIRUS; IDENTIFICATION; INFECTION AB Rapid pathogen detection is crucial for the timely introduction of therapeutics. Two groups (one in the United Kingdom and one in the United States) independently evaluated inhibitor-resistant PCR reagents for the direct testing of substrates. In the United Kingdom, a multiplexed Bacillus anthracis (target) and Bacillus subtilis (internal-control) PCR was used to evaluate 4 reagents against 5 PCR inhibitors and down-selected the TaqMan Fast Virus 1-Step master mix (Life Technologies Inc.). In the United States, four real-time PCR assays (targeting B. anthracis, Brucella melitensis, Venezuelan equine encephalitis virus [VEEV], and Orthopoxvirus spp.) were used to evaluate 5 reagents (plus the Fast Virus master mix) against buffer, blood, and soil samples and down-selected the KAPA Blood Direct master mix (KAPA Biosystems Inc.) with added Platinum Taq (Life Technologies). The down-selected reagents underwent further testing. In the United Kingdom experiments, both reagents were tested against seven contrived aerosol collector samples containing B. anthracis Ames DNA and B. subtilis spores from a commercial formulation (BioBall). In PCR assays with reaction mixtures containing 40% crude sample, an airfield-collected sample induced inhibition of the B. subtilis PCR with the KAPA reagent and complete failure of both PCRs with the Fast Virus reagent. However, both reagents allowed successful PCR for all other samples-which inhibited PCRs with a non-inhibitor-resistant reagent. In the United States, a cross-assay limit-of-detection (LoD) study in blood was conducted. The KAPA Blood Direct reagent allowed the detection of agent DNA (by four PCRs) at higher concentrations of blood in the reaction mixture (2.5%) than the Fast Virus reagent (0.5%), although LoDs differed between assays and reagent combinations. Across both groups, the KAPA Blood Direct reagent was determined to be the optimal reagent for inhibition relief in PCR. C1 [Minogue, Timothy D.; Hall, Adrienne Trombley; Koehler, Jeffery W.] US Army Med Res Inst Infect Dis, Frederick, MD USA. [Rachwal, Phillip A.; Weller, Simon A.] Def Sci & Technol Lab, Salisbury, Wilts, England. RP Weller, SA (reprint author), Def Sci & Technol Lab, Salisbury, Wilts, England. EM sweller@mail.dstl.gov.uk FU Ministry of Defense (MoD); Defense Threat Reduction Agency (DTRA) FX The United Kingdom study was funded by the Ministry of Defense (MoD) Programme Directorate. The U.S. study was funded by the Defense Threat Reduction Agency (DTRA). Collaboration between the DSTL and USAMRIID was facilitated by the Technical Cooperation Program (TTCP), specifically Technical Panel 14 (Rapid Diagnostics). NR 32 TC 6 Z9 6 U1 3 U2 16 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA SN 0099-2240 EI 1098-5336 J9 APPL ENVIRON MICROB JI Appl. Environ. Microbiol. PD FEB PY 2014 VL 80 IS 4 BP 1322 EP 1329 DI 10.1128/AEM.03478-13 PG 8 WC Biotechnology & Applied Microbiology; Microbiology SC Biotechnology & Applied Microbiology; Microbiology GA AB2LV UT WOS:000331625100011 PM 24334660 ER PT J AU Sipos, ML Bar-Haim, Y Abend, R Adler, AB Bliese, PD AF Sipos, Maurice L. Bar-Haim, Yair Abend, Rany Adler, Amy B. Bliese, Paul D. TI POSTDEPLOYMENT THREAT-RELATED ATTENTION BIAS INTERACTS WITH COMBAT EXPOSURE TO ACCOUNT FOR PTSD AND ANXIETY SYMPTOMS IN SOLDIERS SO DEPRESSION AND ANXIETY LA English DT Article DE attention bias; anxiety; combat exposure; difference scores; polynomial regression; PTSD ID POSTTRAUMATIC-STRESS-DISORDER; EMOTIONAL DISORDERS; GENERALIZED ANXIETY; SUPPRESSION; INFORMATION; DEPRESSION; CHECKLIST; COGNITION; BEHAVIOR; SCORES AB BackgroundRecent studies suggest that assessment of threat-related attention bias may be useful in identifying soldiers at risk for clinical symptoms. The present study assessed the degree to which soldiers experienced combat events and showed attentional threat avoidance affected their reported levels of post-traumatic stress disorder (PTSD) and anxiety symptoms. MethodsFour months after a combat deployment to Iraq, 63 US soldiers completed a survey assessing combat exposures and clinical symptoms as well as a dot-probe task assessing threat-related attention bias. ResultsSignificant three-way interactions regressing threat reaction times (RTs), neutral RTs, and combat exposure on PTSD and anxiety symptoms were observed. Specifically, soldiers with high levels of combat exposure, who were more likely to demonstrate attentional bias away from threat, were also more symptomatic. ConclusionThese results demonstrate the potential of threat-related attention bias as a behavioral marker of PTSD and anxiety symptoms in a high-risk military occupational context. Published 2013. C1 [Sipos, Maurice L.; Bliese, Paul D.] Walter Reed Army Inst Res, Ctr Mil Psychiat & Neurosci, Silver Spring, MD 20910 USA. [Bar-Haim, Yair; Abend, Rany] Tel Aviv Univ, Sch Psychol Sci, IL-69978 Tel Aviv, Israel. [Adler, Amy B.] Walter Reed Army Inst Res, US Army Med Res Unit Europe, Heidelberg, Germany. RP Sipos, ML (reprint author), Walter Reed Army Inst Res, Ctr Mil Psychiat & Neurosci, 503 Robert Grant Ave, Silver Spring, MD 20910 USA. EM maurice.sipos@us.army.mil FU Military Operational Medicine Research Program, US Army Medical Research and Materiel Command FX We thank Steve Terry, Rachel Eckford, Victor Martinez, Angela Salvi (Lead Research Associate), Heather Foran, and Lyndon Riviere. This study was funded by the Military Operational Medicine Research Program, US Army Medical Research and Materiel Command. NR 34 TC 9 Z9 9 U1 0 U2 19 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 1091-4269 EI 1520-6394 J9 DEPRESS ANXIETY JI Depress. Anxiety PD FEB PY 2014 VL 31 IS 2 BP 124 EP 129 DI 10.1002/da.22157 PG 6 WC Psychology, Clinical; Psychiatry; Psychology SC Psychology; Psychiatry GA AA6EA UT WOS:000331190400004 PM 23959788 ER PT J AU Walsh, TB Dayton, CJ Erwin, MS Muzik, M Busuito, A Rosenblum, KL AF Walsh, Tova B. Dayton, Carolyn J. Erwin, Michael S. Muzik, Maria Busuito, Alexandra Rosenblum, Katherine L. TI Fathering after Military Deployment: Parenting Challenges and Goals of Fathers of Young Children SO HEALTH & SOCIAL WORK LA English DT Article DE family relationships; fathers; military; reintegration; young children ID MENTAL-HEALTH PROBLEMS; IRAQ; SENSITIVITY; AFGHANISTAN; FAMILIES; MALTREATMENT; ATTACHMENT; MEMBERS; COMBAT; INFANT AB Although often eagerly anticipated, reunication after deployment poses challenges for families, including adjusting to the parent-soldier's return, re-establishing roles and routines, and the potentially necessary accommodation to combat-related injuries or psychological effects. Fourteen male service members, previously deployed to a combat zone, parent to at least one child under seven years of age, were interviewed about their relationships with their young children. Principles of grounded theory guided data analysis to identify key themes related to parenting young children after deployment. Participants reported significant levels of parenting stress and identified specific challenges, including difficulty reconnecting with children, adapting expectations from military to family life, and coparenting. Fathers acknowledged regret about missing an important period in their child's development and indicated a strong desire to improve their parenting skills. They described a need for support in expressing emotions, nurturing, and managing their tempers. Results affirm the need for support to military families during reintegration and demonstrate that military fathers are receptive to opportunities to engage in parenting interventions. Helping fathers understand their children's behavior in the context of age-typical responses to separation and reunion may help them to renew parent-child relationships and reengage in optimal parenting of their young children. C1 [Walsh, Tova B.] Univ Wisconsin Madison, Madison, WI USA. [Dayton, Carolyn J.] Wayne State Univ, Sch Social Work, Detroit, MI USA. [Erwin, Michael S.] US Army, Highland Falls, NY USA. [Busuito, Alexandra] Penn State Univ, Dept Psychol, University Pk, PA 16802 USA. [Rosenblum, Katherine L.] Univ Michigan, Dept Psychiat, Ann Arbor, MI 48109 USA. [Rosenblum, Katherine L.] Univ Michigan, Comprehens Depress Ctr, Ann Arbor, MI 48109 USA. RP Rosenblum, KL (reprint author), Univ Michigan, Dept Psychiat, 4250 Plymouth Rd, Ann Arbor, MI 48109 USA. EM katier@med.umich.edu NR 25 TC 6 Z9 6 U1 1 U2 22 PU OXFORD UNIV PRESS INC PI CARY PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA SN 0360-7283 EI 1545-6854 J9 HEALTH SOC WORK JI Health Soc. Work PD FEB PY 2014 VL 39 IS 1 SI SI BP 35 EP 44 DI 10.1093/hsw/hlu005 PG 10 WC Social Work SC Social Work GA AC7XC UT WOS:000332745700005 PM 24693602 ER PT J AU Orton, SL Chiarito, VP Minor, JK Coleman, TG AF Orton, Sarah L. Chiarito, Vincent P. Minor, Jared K. Coleman, Thomas G. TI Experimental Testing of CFRP-Strengthened Reinforced Concrete Slab Elements Loaded by Close-In Blast SO JOURNAL OF STRUCTURAL ENGINEERING LA English DT Article DE Composite materials; Fiber reinforced polymer; Blasting; Reinforced concrete; Walls; Concrete slabs; Composites; Carbon fiber-reinforced polymers; Close-in blast; Reinforced concrete wall; Shock and vibratory effects ID BOX-TYPE STRUCTURES; FIBER AB Strengthening reinforced concrete slab or wall structural elements with carbon fiber-reinforced polymer (CFRP) can improve their blast resistance. However, close-in blasts (blasts with a scaled range of less than 0.4m/kg1/3) may undermine the effectiveness of the CFRP strengthening. This paper presents an experimental testing program on CFRP-strengthened reinforced concrete slab specimens that utilized fiber anchors. Two CFRP mitigation designs were tested under blast loads with a scaled range of 0.4 and 0.6m/kg1/3. Tests on unmitigated reinforced concrete slab specimens provided baseline comparisons. The experimental results showed that the use of CFRP strengthening improved the blast resistance of reinforced concrete slab specimens. For a larger scaled range, 0.6m/kg1/3, the CFRP successfully prevented flying debris and reduced the overall deflections of the slab specimens. However, for the closer scaled range, 0.4m/kg1/3, the high shock blast pressures shattered the concrete through the thickness of the slab specimen and tore through the back-face CFRP. However, back-face velocity and overall deflections were reduced by about 75% compared to the baseline test slab specimen. C1 [Orton, Sarah L.] Univ Missouri, Columbia, MO 65211 USA. [Chiarito, Vincent P.; Minor, Jared K.] US Army Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. [Coleman, Thomas G.] Atlantic City Int Airport, US Dept Homeland Secur, Transportat Secur Lab, Atlantic City, NJ 08405 USA. RP Orton, SL (reprint author), Univ Missouri, E2503 Lafferre Hall, Columbia, MO 65211 USA. EM ortons@missouri.edu FU Science and Technology Directorate of the Department of Homeland Security FX This research effort was supported by the Science and Technology Directorate of the Department of Homeland Security. Permission to publish was granted by the Department of Homeland Security and the Director, Geotechnical & Structures Laboratory. NR 24 TC 1 Z9 1 U1 7 U2 17 PU ASCE-AMER SOC CIVIL ENGINEERS PI RESTON PA 1801 ALEXANDER BELL DR, RESTON, VA 20191-4400 USA SN 0733-9445 EI 1943-541X J9 J STRUCT ENG JI J. Struct. Eng. PD FEB 1 PY 2014 VL 140 IS 2 DI 10.1061/(ASCE)ST.1943-541X.0000821 PG 9 WC Construction & Building Technology; Engineering, Civil SC Construction & Building Technology; Engineering GA AC4IO UT WOS:000332484800001 ER PT J AU Chantawansri, TL Sliozberg, YR AF Chantawansri, Tanya L. Sliozberg, Yelena R. TI Computational study of the morphology and mechanical properties of dilute ABC triblock copolymers SO KOREA-AUSTRALIA RHEOLOGY JOURNAL LA English DT Article DE multicomponent micelles; morphology; mechanical properties; dissipative particle dynamics; computational modeling ID DISSIPATIVE PARTICLE DYNAMICS; MULTICOMPARTMENT MICELLES; MOLECULAR-DYNAMICS; SELECTIVE SOLVENTS; BLOCK-COPOLYMERS; STAR TERPOLYMERS; BILAYER SHEETS; POLYMER MELTS; SIMULATION; VESICLES AB Dissipative particle dynamics was used to predict the morphology and mechanical properties of unentangled linear ABC triblock copolymer gels, where the midblock is solvophilic. By varying the A, B, and C fraction in the triblock, we observe a variety of multicomponent micelles in addition to singular A and C micelles. These multicomponent micelles include sphere-on-sphere micelles, multi-sphere-on-sphere, worm-like micelles, and branched micelles. Simulation cells were also subjected to deformation under uni-axial tension, and correlated to the extent of macrophase separation. Values of elastic modulus were also extracted from the calculated stress using the theory of linear elasticity. Extracted values of the modulus are shown to scale inversely with the midblock length which agrees with other theoretical predictions. C1 [Chantawansri, Tanya L.; Sliozberg, Yelena R.] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. [Sliozberg, Yelena R.] Bowhead Sci & Technol, King George, VA 22485 USA. RP Chantawansri, TL (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. EM tanya.chantawansri.civ@mail.mil FU AFRL through the Challenge Project [C5M] FX Calculations were performed on DOD High Performance Computing site at the AFRL through the Challenge Project C5M. NR 40 TC 1 Z9 1 U1 1 U2 44 PU KOREAN SOC RHEOLOGY PI SEOUL PA KOREA SCI TECHNOLOGY CENTER, 635-4 YUKSAM-DONG, STE 806, KANGNAM-GOO, SEOUL 135-703, SOUTH KOREA SN 1226-119X EI 2093-7660 J9 KOREA-AUST RHEOL J JI Korea-Aust. Rheol. J. PD FEB PY 2014 VL 26 IS 1 BP 49 EP 61 DI 10.1007/s13367-014-0006-4 PG 13 WC Mechanics; Polymer Science SC Mechanics; Polymer Science GA AC1OY UT WOS:000332267100006 ER PT J AU Yu, Y Fuscoe, JC Zhao, C Guo, C Jia, MW Qing, T Bannon, DI Lancashire, L Bao, WJ Du, TT Luo, H Su, ZQ Jones, WD Moland, CL Branham, WS Qian, F Ning, BT Li, Y Hong, HX Guo, L Mei, N Shi, TL Wang, KY Wolfinger, RD Nikolsky, Y Walker, SJ Duerksen-Hughes, P Mason, CE Tong, WD Thierry-Mieg, J Thierry-Mieg, D Shi, LM Wang, C AF Yu, Ying Fuscoe, James C. Zhao, Chen Guo, Chao Jia, Meiwen Qing, Tao Bannon, Desmond I. Lancashire, Lee Bao, Wenjun Du, Tingting Luo, Heng Su, Zhenqiang Jones, Wendell D. Moland, Carrie L. Branham, William S. Qian, Feng Ning, Baitang Li, Yan Hong, Huixiao Guo, Lei Mei, Nan Shi, Tieliu Wang, Kevin Y. Wolfinger, Russell D. Nikolsky, Yuri Walker, Stephen J. Duerksen-Hughes, Penelope Mason, Christopher E. Tong, Weida Thierry-Mieg, Jean Thierry-Mieg, Danielle Shi, Leming Wang, Charles TI A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages SO NATURE COMMUNICATIONS LA English DT Article ID MOUSE GENE-EXPRESSION; GENOME; LIVER; IDENTIFICATION; INFORMATION; LANDSCAPE; MODENCODE; ELEMENTS; DATABASE; DISEASE AB The rat has been used extensively as a model for evaluating chemical toxicities and for understanding drug mechanisms. However, its transcriptome across multiple organs, or developmental stages, has not yet been reported. Here we show, as part of the SEQC consortium efforts, a comprehensive rat transcriptomic BodyMap created by performing RNA-Seq on 320 samples from 11 organs of both sexes of juvenile, adolescent, adult and aged Fischer 344 rats. We catalogue the expression profiles of 40,064 genes, 65,167 transcripts, 31,909 alternatively spliced transcript variants and 2,367 non-coding genes/non-coding RNAs (ncRNAs) annotated in AceView. We find that organ-enriched, differentially expressed genes reflect the known organ-specific biological activities. A large number of transcripts show organ-specific, age-dependent or sex-specific differential expression patterns. We create a web-based, open-access rat BodyMap database of expression profiles with crosslinks to other widely used databases, anticipating that it will serve as a primary resource for biomedical research using the rat model. C1 [Yu, Ying; Zhao, Chen; Jia, Meiwen; Qing, Tao; Du, Tingting; Luo, Heng; Shi, Leming] Fudan Univ, Sch Life Sci & Pharm, Ctr Pharmacogen, State Key Lab Genet Engn, Shanghai 201203, Peoples R China. [Yu, Ying; Zhao, Chen; Jia, Meiwen; Qing, Tao; Du, Tingting; Luo, Heng; Shi, Leming] Fudan Univ, Sch Life Sci & Pharm, MOE Key Lab Contemporary Anthropol, Shanghai 201203, Peoples R China. [Fuscoe, James C.; Su, Zhenqiang; Moland, Carrie L.; Branham, William S.; Qian, Feng; Ning, Baitang; Li, Yan; Hong, Huixiao; Guo, Lei; Mei, Nan; Tong, Weida; Shi, Leming] US FDA, Natl Ctr Toxicol Res, Jefferson, AR 92079 USA. [Bannon, Desmond I.] Army Inst Publ Hlth, US Army Publ Hlth Command, Aberdeen Proving Ground, MD 21010 USA. [Lancashire, Lee] IP & Sci Thomson Reuters, London EC1N 8JS, England. [Bao, Wenjun; Wolfinger, Russell D.] SAS Inst Inc, Cary, NC 27513 USA. [Jones, Wendell D.] Express Anal Inc, Durham, NC 27713 USA. [Shi, Tieliu] Coll Life Sci, Ctr Bioinformat, Shanghai 200241, Peoples R China. [Shi, Tieliu] Coll Life Sci, Inst Biomed Sci, Shanghai 200241, Peoples R China. [Wang, Kevin Y.] Johns Hopkins Univ, Sch Med, Baltimore, MD 21205 USA. [Walker, Stephen J.] Wake Forest Univ Hlth Sci, Wake Forest Inst Regenerat Med, Winston Salem, NC 27157 USA. [Duerksen-Hughes, Penelope] Loma Linda Univ, Sch Med, Dept Basic Sci, Loma Linda, CA 92350 USA. [Mason, Christopher E.] Cornell Univ, Dept Physiol & Biophys, New York, NY 10021 USA. [Mason, Christopher E.] Cornell Univ, Inst Computat Biomed, New York, NY 10021 USA. [Thierry-Mieg, Jean; Thierry-Mieg, Danielle] Natl Inst Hlth, Natl Ctr Biotechnol Informat, Bethesda, MD 20894 USA. [Shi, Leming] Fudan Zhangjiang Ctr Clin Genom, Shanghai 201203, Peoples R China. [Shi, Leming] Zhangjiang Ctr Translat Med, Shanghai 201203, Peoples R China. [Wang, Charles] Loma Linda Univ, Sch Med, Ctr Genom & Div Microbiol Mol Genet, Loma Linda, CA 92350 USA. RP Wang, C (reprint author), Loma Linda Univ, Sch Med, Ctr Genom & Div Microbiol Mol Genet, Loma Linda, CA 92350 USA. EM leming.shi@gmail.com; oxwang@gmail.com RI Guo, Chao/B-2647-2010; mei, nan/E-8915-2011; Luo, Heng/D-3616-2016; THIERRY-MIEG, Jean/F-1975-2017 OI Guo, Chao/0000-0002-6673-0933; mei, nan/0000-0002-3501-9014; Luo, Heng/0000-0001-5192-8878; THIERRY-MIEG, Jean/0000-0002-0396-6789 FU US Food and Drug Administrative Agency (FDA); FDA Office of Women's Health, China's Program of Global Experts; National Institutes of Health's (NIH) Intramural Research Program; National 973 Key Basic Research Program of China [2010CB945401]; National Natural Science Foundation of China [31240038, 31071162]; Science and Technology Commission of Shanghai Municipality [11DZ2260300]; China's National Super-computing Center of Tianjin; NIH/NCBI's Supercomputing Center; USA FDA's Supercomputing Center FX The views presented in this article do not necessarily reflect current or future opinion or policy of the US Food and Drug Administration. Any mention of commercial products is for clarification and not intended as an endorsement. This work was supported in part by the US Food and Drug Administrative Agency (FDA), the FDA Office of Women's Health, China's Program of Global Experts, the National Institutes of Health's (NIH) Intramural Research Program, the National 973 Key Basic Research Program of China (2010CB945401), the National Natural Science Foundation of China (31240038 and 31071162) and the Science and Technology Commission of Shanghai Municipality (11DZ2260300). We gratefully acknowledge support by the China's National Super-computing Center of Tianjin, the NIH/NCBI's Supercomputing Center and the USA FDA's Supercomputing Center. We also thank Drs. Keely Walker, David Klein, Marina Bessarabova and Donna Mendrick for critical review of an earlier version of the manuscript. NR 43 TC 49 Z9 51 U1 1 U2 39 PU NATURE PUBLISHING GROUP PI LONDON PA MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND SN 2041-1723 J9 NAT COMMUN JI Nat. Commun. PD FEB PY 2014 VL 5 AR 3230 DI 10.1038/ncomms4230 PG 11 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA AC6WG UT WOS:000332665700005 PM 24510058 ER PT J AU Bantum, EO Albright, CL White, KK Berenberg, JL Layi, G Ritter, PL Laurent, D Plant, K Lorig, K AF Bantum, Erin O'Carroll Albright, Cheryl L. White, Kami K. Berenberg, Jeffrey L. Layi, Gabriela Ritter, Phillip L. Laurent, Diana Plant, Katy Lorig, Kate TI Surviving and Thriving With Cancer Using a Web-Based Health Behavior Change Intervention: Randomized Controlled Trial SO JOURNAL OF MEDICAL INTERNET RESEARCH LA English DT Article DE cancer survivors; online interventions; social support ID DISEASE SELF-MANAGEMENT; PRIMARY BREAST-CANCER; PSYCHOLOGICAL ADJUSTMENT; OVARIAN-CANCER; FATIGUE; SUPPORT; WOMEN; OUTCOMES AB Background: Given the substantial improvements in cancer screening and cancer treatment in the United States, millions of adult cancer survivors live for years following their initial cancer diagnosis and treatment. However, latent side effects can occur and some symptoms can be alleviated or managed effectively via changes in lifestyle behaviors. Objective: The purpose of this study was to test the effectiveness of a six-week Web-based multiple health behavior change program for adult survivors. Methods: Participants (n=352) were recruited from oncology clinics, a tumor registry, as well as through online mechanisms, such as Facebook and the Association of Cancer Online Resources (ACOR). Cancer survivors were eligible if they had completed their primary cancer treatment from 4 weeks to 5 years before enrollment. Participants were randomly assigned to the Web-based program or a delayed-treatment control condition. Results: In total, 303 survivors completed the follow-up survey (six months after completion of the baseline survey) and participants in the Web-based intervention condition had significantly greater reductions in insomnia and greater increases in minutes per week of vigorous exercise and stretching compared to controls. There were no significant changes in fruit and vegetable consumption or other outcomes. Conclusions: The Web-based intervention impacted insomnia and exercise; however, a majority of the sample met or exceeded national recommendations for health behaviors and were not suffering from depression or fatigue at baseline. Thus, the survivors were very healthy and well-adjusted upon entry and their ability to make substantial health behavior changes may have been limited. Future work is discussed, with emphasis placed on ways in which Web-based interventions can be more specifically analyzed for benefit, such as in regard to social networking. C1 [Bantum, Erin O'Carroll; White, Kami K.; Berenberg, Jeffrey L.; Layi, Gabriela] Univ Hawaii, Ctr Canc, Honolulu, HI 96813 USA. [Albright, Cheryl L.] Univ Hawaii Manoa, Honolulu, HI 96822 USA. [Berenberg, Jeffrey L.] Tripler Army Med Ctr, Honolulu, HI 96859 USA. [Ritter, Phillip L.; Laurent, Diana; Lorig, Kate] Stanford Univ, Sch Med, Stanford Patient Educ Res Ctr, Palo Alto, CA 94304 USA. [Plant, Katy] Natl Council Aging, Washington, DC USA. RP Bantum, EO (reprint author), Univ Hawaii, Ctr Canc, 701 Ilalo St,B4, Honolulu, HI 96813 USA. EM ebantum@cc.hawaii.edu FU Department of Defense [W81XWH-06-2-0042]; Stanford Cancer Center FX There are many people to thank for their help and involvement with the study. We would first like to thank the participants for their willingness and interest in the study. We also thank Ross Yamato for his help with online recruitment and thank-you's to participants. Thank you to Carolyn Gotay for securing the original funding for the project and to Ian Pagano for his help in some of the early statistical analyses, as well as Lynne Wilkens for her oversight of the analysis process and her helpful editing of the manuscript. We would also like to thank the Department of Defense and Stanford Cancer Center for funding this project (Department of Defense W81XWH-06-2-0042, Developmental Cancer Research Award from Stanford Cancer Center), in addition to all of the sites that helped with recruitment, including the facilitators of websites that posted our recruitment ad. NR 39 TC 12 Z9 12 U1 2 U2 18 PU JMIR PUBLICATIONS, INC PI TORONTO PA 59 WINNERS CIRCLE, TORONTO, ON M4L 3Y7, CANADA SN 1438-8871 J9 J MED INTERNET RES JI J. Med. Internet Res. PD FEB PY 2014 VL 16 IS 2 AR e54 DI 10.2196/jmir.3020 PG 12 WC Health Care Sciences & Services; Medical Informatics SC Health Care Sciences & Services; Medical Informatics GA AC3EJ UT WOS:000332397500009 PM 24566820 ER PT J AU Levine, F Kayea, RV Wexler, R Sadvary, DJ Melick, C La Scala, J AF Levine, Felicia Kayea, Ronald V., III Wexler, Robert Sadvary, D. J. Melick, Cory La Scala, John TI Heats of Combustion of Fatty Acids and Fatty Acid Esters SO JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY LA English DT Article DE JP-8; Biodiesel; Heat of combustion; Fatty acids; FAME; Group contribution method; Modeling ID BIODIESEL; STABILITY; FUELS AB The military uses JP-8, a kerosene type hydrocarbon, to fuel most of its vehicles and is seeking a renewable alternative fuel that meets strict JP-8 specifications. Biodiesel is typically a mixture of different alkyl esters produced from the transesterification of triglycerides readily available in plant oils and used cooking oil. To date, no traditional biodiesel meets the requirements for heat of combustion, freezing point, viscosity and oxidative stability to be a stand-alone replacement for JP-8. This work is a fundamental survey of the heat of combustion of single fatty acid esters and a predictive model for estimating the heat of combustion given a known molecular structure. The gross heat of combustion of various C6-C18 fatty acids and the methyl, propyl and isopropyl esters of these fatty acids was measured. This study sought to relate the effect of chain length, degree of unsaturation and branching to the critical fuel property of the gross heat of combustion (H-c). It was found that H-c (kJ/g) increased with chain length. A nearly linear relationship was found between wt% carbon and hydrogen, and H-c. Group contribution models previously published for hydrocarbons and polymers were modified to more accurately predict the heat of combustion of the fatty acids and esters. Modification of the molar heat values of carboxylic acid, methyl, and methylene groups improved correlation of the model with the experimental results. C1 [Levine, Felicia] US Army Res Lab, Data Matrix Solut Inc, RDRL WMM C, Aberdeen Proving Ground, MD 21005 USA. [Kayea, Ronald V., III; Wexler, Robert; Sadvary, D. J.; Melick, Cory] Drexel Univ, Oak Ridge Inst Sci & Educ ORISE, Philadelphia, PA 19104 USA. [La Scala, John] US Army Res Lab, RDRL WMM C, Aberdeen Proving Ground, MD 21005 USA. RP Levine, F (reprint author), US Army Res Lab, Data Matrix Solut Inc, RDRL WMM C, 4600 Deer Creek Loop, Aberdeen Proving Ground, MD 21005 USA. EM felicia.levine.ctr@mail.mil FU US Army Research Laboratory FX This research was supported in part by an appointment to the Student Research Participation Program at the US Army Research Laboratory administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the US Department of Energy and USARL. NR 27 TC 4 Z9 4 U1 1 U2 18 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 0003-021X EI 1558-9331 J9 J AM OIL CHEM SOC JI J. Am. Oil Chem. Soc. PD FEB PY 2014 VL 91 IS 2 BP 235 EP 249 DI 10.1007/s11746-013-2367-0 PG 15 WC Chemistry, Applied; Food Science & Technology SC Chemistry; Food Science & Technology GA AC6WQ UT WOS:000332666800005 ER PT J AU Wall, WA Douglas, NA Hoffmann, WA Wentworth, TR Gray, JB Xiang, QYJ Knaus, BK Hohmann, MG AF Wall, Wade A. Douglas, Norman A. Hoffmann, William A. Wentworth, Thomas R. Gray, Janet B. Xiang, Qiu-Yun Jenny Knaus, Brian K. Hohmann, Matthew G. TI Evidence of population bottleneck in Astragalus michauxii (Fabaceae), a narrow endemic of the southeastern United States SO CONSERVATION GENETICS LA English DT Article DE Astragalus; Bottleneck; Endemism; Genetic diversity; Microsatellites; Pinus palustris ID ATLANTIC COASTAL-PLAIN; ALLELE FREQUENCY DATA; GENETIC DIVERSITY; COMPUTER-PROGRAM; NORTH-AMERICA; PLANT; HISTORY; SIZE; ECOSYSTEM; RAREFACTION AB Genetic factors such as decreased genetic diversity and increased homozygosity can have detrimental effects on rare species, and may ultimately limit potential adaptation and exacerbate population declines. The Gulf and Atlantic Coastal Plain physiographic region has the second highest level of endemism in the continental USA, but habitat fragmentation and land use changes have resulted in catastrophic population declines for many species. Astragalus michauxii (Fabaceae) is an herbaceous plant endemic to the region that is considered vulnerable to extinction, with populations generally consisting of fewer than 20 individuals. We developed eight polymorphic microsatellites and genotyped 355 individuals from 24 populations. We characterized the population genetic diversity and structure, tested for evidence of past bottlenecks, and identified evidence of contemporary gene flow between populations. The mean ratios of the number of alleles to the allelic range (M ratio) across loci for A. michauxii populations were well below the threshold of 0.68 identified as indicative of a past genetic bottleneck. Genetic diversity estimates were similar across regions and populations, and comparable to other long-lived perennial species. Within-population genetic variation accounted for 92 % of the total genetic variation found in the species. Finally, there is evidence for contemporary gene flow among the populations in North Carolina. Although genetic factors can threaten rare species, maintaining habitats through prescribed burning, in concert with other interventions such as population augmentation or (re)introduction, are likely most critical to the long term survival of A. michauxii. C1 [Wall, Wade A.; Douglas, Norman A.; Hoffmann, William A.; Wentworth, Thomas R.; Xiang, Qiu-Yun Jenny] N Carolina State Univ, Dept Plant Biol, Raleigh, NC 27695 USA. [Wall, Wade A.; Hohmann, Matthew G.] US Army Corps Engineers, Engn Res & Dev Ctr, Champaign, IL 61826 USA. [Douglas, Norman A.] Oberlin Coll & Conservatory, Dept Biol, Sci Ctr K107, Oberlin, OH 44074 USA. [Gray, Janet B.] Endangered Species Branch, Ft Bragg, NC 28310 USA. [Knaus, Brian K.] Oregon State Univ, Dept Bot & Plant Pathol, Corvallis, OR 97331 USA. RP Wall, WA (reprint author), N Carolina State Univ, Dept Plant Biol, Box 7612, Raleigh, NC 27695 USA. EM Wade.A.Wall@usace.army.mil FU Construction Engineering Research Laboratory (US Army Corps of Engineers) [W9132T-07-2-0019] FX We thank Fort Bragg Military Reservation for access and support and the Construction Engineering Research Laboratory (US Army Corps of Engineers Cooperative Agreement #W9132T-07-2-0019 to W. Hoffmann) for funding. We also thank Bert Pittman, Sherry Emerine, Jacob Hilton, Kristen Kostelnik, Linda Lee, Xiang Liu, the North Carolina Natural Heritage Program, Tom Patrick, Andrew Walker, the Xiang Lab, and three anonymous reviewers. Assistance with microsatellite development was generously provided by Pacific Northwest Research Station (USDA Forest Service). NR 71 TC 4 Z9 4 U1 2 U2 21 PU SPRINGER PI DORDRECHT PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS SN 1566-0621 EI 1572-9737 J9 CONSERV GENET JI Conserv. Genet. PD FEB PY 2014 VL 15 IS 1 BP 153 EP 164 DI 10.1007/s10592-013-0527-2 PG 12 WC Biodiversity Conservation; Genetics & Heredity SC Biodiversity & Conservation; Genetics & Heredity GA AC2UR UT WOS:000332372300012 ER PT J AU Shekh-Ahmad, T Hen, N Yagen, B McDonough, JH Finnell, RH Wlodarczyk, BJ Bialer, M AF Shekh-Ahmad, Tawfeeq Hen, Naama Yagen, Boris McDonough, John H. Finnell, Richard H. Wlodarczyk, Bogdan J. Bialer, Meir TI Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential SO EPILEPSIA LA English DT Article DE Chiral switch; Strereoselective pharmacokinetic and pharmacodynamics analysis; New antiepileptic drugs; CNS drugs ID SOMAN-INDUCED SEIZURES; CHIRAL AMIDE ANALOG; ANTIEPILEPTIC DRUGS; STATUS EPILEPTICUS; HEALTHY-SUBJECTS; UNIQUE ACTIVITY; ISOMER; MECHANISMS; PROFILE; DOGS AB Objective Valnoctamide (VCD), a central nervous system (CNS)-active chiral constitutional isomer of valpromide, the corresponding amide of valproic acid (VPA), is currently undergoing phase IIb clinical trials in acute mania. VCD exhibits stereoselective pharmacokinetics (PK) in animals and humans. The current study comparatively evaluated the pharmacodynamics (PD; anticonvulsant activity and teratogenicity) and PK of the four individual stereoisomers of VCD. Methods The anticonvulsant activity of VCD individual stereoisomers was evaluated in several rodent anticonvulsant models including maximal electroshock, 6Hz psychomotor, subcutaneous metrazol, and the pilocarpine-induced and soman-induced status epilepticus (SE). The PK-PD (anticonvulsant activity) relationship of VCD stereoisomers was evaluated following intraperitoneal administration (70mg/kg) to rats. Induction of neural tube defects (NTDs) by VCD stereoisomers was evaluated in a mouse strain that was highly susceptible to teratogen-induced NTDs. Results VCD had a stereoselective PK, with (2S,3S)-VCD exhibiting the lowest clearance, and consequently a twice-higher plasma exposure than all other stereoisomers. Nervertheless, there was less stereoselectivity in VCD anticonvulsant activity and each stereoisomer had similar median effective dose (ED)(50) values in most models. VCD stereoisomers (258 or 389mg/kg) did not cause NTDs. These doses are 3-12 times higher than VCD anticonvulsant ED50 values. Significance VCD displayed stereoselective PK that did not lead to significant stereoselective activity in various anticonvulsant rodent models. If VCD exerted its broad-spectrum anticonvulsant activity using a single mechanism of action (MOA), it is likely that it would exhibit a stereoselective PD. The fact that there was no significant difference between racemic VCD and its individual stereoisomers suggests that VCD's anticonvulsant activity is due to multiple MOAs. C1 [Shekh-Ahmad, Tawfeeq; Hen, Naama; Yagen, Boris; Bialer, Meir] Hebrew Univ Jerusalem, Inst Drug Res, Fac Med, Sch Pharm, IL-91120 Jerusalem, Israel. [Yagen, Boris; Bialer, Meir] Hebrew Univ Jerusalem, David R Bloom Ctr Pharm, IL-91120 Jerusalem, Israel. [McDonough, John H.] US Army Med Res Inst Chem Def, Pharmacol Branch, Div Res, Aberdeen Proving Ground, MD USA. [Finnell, Richard H.; Wlodarczyk, Bogdan J.] Univ Texas Austin, Dell Pediat Res Inst, Dept Nutr Sci, Austin, TX 78712 USA. RP Bialer, M (reprint author), Hebrew Univ Jerusalem, Inst Drug Res, Fac Med, Sch Pharm, POB 12065, IL-91120 Jerusalem, Israel. EM bialer@md.huji.ac.il OI Wlodarczyk, Bogdan J./0000-0001-5249-5832 FU Israel Ministry of Defense, Medical Branch, Nuclear Biological Chemical (NBC) Protection Division [039-4489, 039-4576]; NIH/NINDS [Y1-O6-9613-01]; USAMRICD [A120-B.P2009-2]; NINDS, NIH [NO1-NS-4-2359] FX This study was supported by an unrestricted research grant (#039-4489 and #039-4576) from Israel Ministry of Defense, Medical Branch, Nuclear Biological Chemical (NBC) Protection Division and by an Inter-Agency Agreement between NIH/NINDS (Y1-O6-9613-01) and USAMRICD (A120-B.P2009-2). This work is abstracted from the PhD thesis of Mr. Tawfeeq Shekh-Ahmad in a partial fulfillment for the requirements of a PhD degree at The Hebrew University of Jerusalem. The authors wish to thank Drs. John H. Kehne and Tracy Chen of the NIH-NINDS-Anticonvulsant Screening Program (ASP) for testing the compounds in the ASP. The authors also wish to acknowledge the technical assistance of the faculty and staff at the University of Utah Anticonvulsant Drug Development (ADD) Program who conducted the in vivo anticonvulsant testing, pilocarpine SE, and in vitro slice studies described in this manuscript. The anticonvulsant studies were supported by NINDS, NIH Contract No. NO1-NS-4-2359. The views expressed in this report are those of the authors and do not reflect the official policy of the Department of Army, Department of Defense or the U.S. Government. The experimental protocol was approved by the Animal Care and Use Committee at the U.S. Army Medical Research Institute of Chemical Defense and all procedures were conducted in accordance with the principles stated in the Guide for the Care and Use of Laboratory Animals (National Research Council, 1996) and the Animal Welfare Act of 1966 (P.L. 89-544), as amended. NR 38 TC 11 Z9 11 U1 0 U2 7 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0013-9580 EI 1528-1167 J9 EPILEPSIA JI Epilepsia PD FEB PY 2014 VL 55 IS 2 BP 353 EP 361 DI 10.1111/epi.12480 PG 9 WC Clinical Neurology SC Neurosciences & Neurology GA AA3WR UT WOS:000331026400021 PM 24313671 ER PT J AU Mizukami, N Clark, MP Slater, AG Brekke, LD Elsner, MM Arnold, JR Gangopadhyay, S AF Mizukami, Naoki Clark, Martyn P. Slater, Andrew G. Brekke, Levi D. Elsner, Marketa M. Arnold, Jeffrey R. Gangopadhyay, Subhrendu TI Hydrologic Implications of Different Large-Scale Meteorological Model Forcing Datasets in Mountainous Regions SO JOURNAL OF HYDROMETEOROLOGY LA English DT Article DE Land surface model; Complex terrain; Climate sensitivity; Reanalysis data ID WESTERN UNITED-STATES; DAILY SOLAR-RADIATION; SYSTEM NLDAS PROJECT; COLORADO RIVER-BASIN; CLIMATE-CHANGE; WATER-RESOURCES; COMPLEX TERRAIN; NORTH-AMERICA; PRECIPITATION; TEMPERATURE AB Process-based hydrologic models require extensive meteorological forcing data, including data on precipitation, temperature, shortwave and longwave radiation, humidity, surface pressure, and wind speed. Observations of precipitation and temperature are more common than other variables; consequently, radiation, humidity, pressure, and wind speed often must be either estimated using empirical relationships with precipitation and temperature or obtained from numerical weather prediction models. This study examines two climate forcing datasets using different methods to estimate radiative energy fluxes and humidity and investigates the effects of the choice of forcing data on hydrologic simulations over the mountainous upper Colorado River basin (293 472 km(2)). Comparisons of model simulations forced by two climate datasets illustrate that the methods used to estimate shortwave radiation impact hydrologic states and fluxes, particularly at high elevation (e.g., ~20% difference in runoff above 3000-m elevation), substantially altering the timing of snowmelt and runoff (~20 days difference) and the partitioning of precipitation between evapotranspiration and runoff. The different forcing datasets also exhibit differences in hydrologic sensitivity to interannual temperature at high elevation. The results suggest that the choice of forcing dataset is an important consideration when conducting climate impact assessments and the subsequent applications of these assessments for water resources planning and management. C1 [Mizukami, Naoki; Clark, Martyn P.] Natl Ctr Atmospher Res, Boulder, CO 80307 USA. [Slater, Andrew G.] Univ Colorado, Cooperat Inst Res Environm Sci, Boulder, CO 80309 USA. [Brekke, Levi D.; Elsner, Marketa M.] Bur Reclamat, Denver, CO USA. [Arnold, Jeffrey R.] US Army Corps Engineers, Seattle, WA USA. [Gangopadhyay, Subhrendu] Bur Reclamat, Denver, CO USA. RP Mizukami, N (reprint author), POB 3000, Boulder, CO 80307 USA. EM mizukami@ucar.edu RI Clark, Martyn/A-5560-2015; Mizukami, Naoki/J-7027-2015; OI Slater, Andrew/0000-0003-0480-8560; Clark, Martyn/0000-0002-2186-2625; SLATER, ANDREW/0000-0002-4009-4844 FU U.S Bureau of Reclamation; U.S Army Corps of Engineers FX The authors thank Dr. Jessica Lundquist and two anonymous reviewers for critical and careful reviews that helped improve the manuscript. The authors also thank Ethan Gutmann, Roy Rasmussen, David Gochis, Kyoko Ikeda, and Pablo Mendoza for discussions at the earlier stage of this research. This work was financially supported by the U.S Bureau of Reclamation and the U.S Army Corps of Engineers. NR 62 TC 19 Z9 19 U1 3 U2 20 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 USA SN 1525-755X EI 1525-7541 J9 J HYDROMETEOROL JI J. Hydrometeorol. PD FEB PY 2014 VL 15 IS 1 BP 474 EP 488 DI 10.1175/JHM-D-13-036.1 PG 15 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA AC2BI UT WOS:000332301900027 ER PT J AU Ciminiello, P Dell'Aversano, C Dello Lacovo, E Forino, M Tartaglione, L Pelin, M Sosa, S Tubaro, A Chaloin, O Poli, M Bignami, G AF Ciminiello, Patrizia Dell'Aversano, Carmela Dello Lacovo, Emma Forino, Martino Tartaglione, Luciana Pelin, Marco Sosa, Silvio Tubaro, Aurelia Chaloin, O. Poli, Mark Bignami, Gary TI Stereoisomers of 42-Hydroxy Palytoxin from Hawaiian Palythoa toxica and P. tuberculosa: Stereostructure Elucidation, Detection, and Biological Activities SO JOURNAL OF NATURAL PRODUCTS LA English DT Article ID STEREOCHEMISTRY; COELENTERATE; ZOANTHIDS; SAMPLES; ANALOGS AB Palytoxin ranks among the most potent marine biotoxins. Its lethality was well known to native Hawaiians that used to smear a "moss"containing the toxin on their spears to cause instant death to their victims. Human intoxications due to exposure to palytoxin and to its many congeners have been reported worldwide. Currently, palytoxins constitute the main threat to public health across the Mediterranean Sea. In the present work we report on the isolation and stereostructural determination of a new palytoxin analogue from a Hawaiian Palythoa tuberculosa sample. This new toxin is a stereoisomer of 42-hydroxypalytoxin isolated from Palythoa toxica. The whole absolute configuration of this latter toxin is also reported in the paper. Interestingly, the two 42-hydroxypalytoxins do not share the same biological activity. The stereoisomer from P. tuberculosa showed cytotoxicity toward skin. HaCaT keratinocytes approximately 1 order of magnitude lower than that of 42-hydroxypalytoxin from P. toxica and about 2 orders of magnitude lower than that of palytoxin itself. This finding holds the prospect of interesting structure-activity relationship evaluations in the future. C1 [Ciminiello, Patrizia; Dell'Aversano, Carmela; Dello Lacovo, Emma; Forino, Martino; Tartaglione, Luciana] Univ Naples Federico II, Dept Pharm, I-80131 Naples, Italy. [Pelin, Marco; Sosa, Silvio; Tubaro, Aurelia] Univ Trieste, Dept Life Sci, I-34127 Trieste, Italy. [Chaloin, O.] CNRS, Inst Biol Mol & Cellulaire, Lab Immunol & Chim Therapeut, F-67000 Strasbourg, France. [Poli, Mark] US Army Med Res Inst Infect Dis, Ft Detrick, MD 21701 USA. [Bignami, Gary] Bignami Consulting, Honolulu, HI USA. RP Forino, M (reprint author), Univ Naples Federico II, Dept Pharm, Via D Montesano 49, I-80131 Naples, Italy. EM forino@unina.it RI Dell'Aversano, Carmela/H-1803-2013; OI Dell'Aversano, Carmela/0000-0001-8337-3029; Tartaglione, Luciana/0000-0003-0742-6955; Forino, Martino/0000-0001-8036-3546 NR 29 TC 11 Z9 11 U1 0 U2 19 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0163-3864 EI 1520-6025 J9 J NAT PROD JI J. Nat. Prod. PD FEB PY 2014 VL 77 IS 2 BP 351 EP 357 DI 10.1021/np4009514 PG 7 WC Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy SC Plant Sciences; Pharmacology & Pharmacy GA AC2SQ UT WOS:000332354700022 PM 24512352 ER PT J AU Fink, DS Gallaway, MS Millikan, AM AF Fink, David S. Gallaway, M. Shayne Millikan, Amy M. TI An Examination of Successful Soldier Postdeployment Transition From Combat to Garrison Life SO JOURNAL OF TRAUMATIC STRESS LA English DT Article ID SOCIAL SUPPORT; PSYCHOLOGICAL-RESILIENCE; HEALTH; VETERANS; BARRIERS; STIGMA; STRESS; CARE AB Previous studies have shown that combat exposures and deployment-related stressors have negative implications on soldiers' postdeployment health and well-being. The current study aimed to examine the individual and combined effects of organizational and social support on the success of soldiers' postdeployment reintegration. In this study, 2,922 U.S. soldiers were surveyed from a brigade combat team at 90-120 days postdeployment, measuring soldiers' perceptions of postdeployment transition home, occupational and social support, stigma and barriers associated with accessing behavioral health care, and previous behavioral health care. Logistic regression analysis indicated that soldiers reporting a positive postdeployment transition home (n= 1,776; 61%) was significantly associated with leadership perceptions, adjusted odds ratio (AOR)= 1.19, 95% confidence interval (CI) [1.02, 1.39], unit cohesion, AOR= 1.29, 95% CI [1.09, 1.53], personal support, AOR= 1.37, 95% CI [1.23, 1.52], perceived levels of stigma, AOR= 0.73, 95% CI [0.65, 0.82] barriers to accessing care, AOR= 0.86, 95% CI [0.76, 0.97], and previously accessing behavioral health care, AOR= 0.34, 95% CI [0.28, 0.43]. These findings suggest redeploying soldiers may benefit from programs aimed at improving self-efficacy and coping through fostering occupational and social support, with special concern taken to reduce stigma and barriers to care across the Army. C1 [Fink, David S.; Gallaway, M. Shayne; Millikan, Amy M.] US Army Publ Hlth Command, US Army Inst Publ Hlth, BSHOP, Aberdeen Proving Ground, MD USA. RP Gallaway, MS (reprint author), 5158 Blackhawk Rd, Aberdeen Proving Ground, MD USA. EM shayne.gallaway@us.army.mil OI Fink, David/0000-0003-1531-1525 NR 18 TC 3 Z9 3 U1 2 U2 8 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0894-9867 EI 1573-6598 J9 J TRAUMA STRESS JI J. Trauma Stress PD FEB PY 2014 VL 27 IS 1 BP 98 EP 102 DI 10.1002/jts.21876 PG 5 WC Psychology, Clinical; Psychiatry SC Psychology; Psychiatry GA AA7NR UT WOS:000331284600013 PM 24375732 ER PT J AU Rees, B Travis, F Shapiro, D Chant, R AF Rees, Brian Travis, Fred Shapiro, David Chant, Ruth TI Significant Reductions in Posttraumatic Stress Symptoms in Congolese Refugees Within 10 days of Transcendental Meditation Practice SO JOURNAL OF TRAUMATIC STRESS LA English DT Article ID CHECKLIST; ATTENTION; PTSD AB This follow-up pilot study tested whether Transcendental Meditation (R) (TM) practice would significantly reduce symptoms of posttraumatic stress in Congolese refugees within 10days after instruction. The Posttraumatic Stress Disorder Checklist-Civilian (PCL-C) was administered to nonmatched waitlist controls from a previous study 3 times over a 90-day period. Within 8days of the third baseline measure, 11 refugees were taught TM, then retested 10days and 30days after instruction. Average PCL-C scores dropped 29.9 points from 77.9 to 48.0 in 10days, then dropped another 12.7 points to 35.3 at 30days. Effect size at 10days was high (d = 4.05). There were no adverse events. All participants completed the study and were able to practice TM. C1 [Rees, Brian] 63d Reg Support Command, US Army Reserve, Med Corps, Moffett Field, CA USA. [Travis, Fred] MUM Res Inst, Ctr Brain Consciousness & Cognit, Fairfield, IA USA. [Shapiro, David] Inst Sci Technol & Publ Policy, Fairfield, IA USA. [Chant, Ruth] MUM Netherlands, Stn 24, Vlodrop, Netherlands. RP Rees, B (reprint author), 1890 Diablo Dr, San Luis Obispo, CA 93405 USA. EM brian.m.rees2.mil@mail.mil NR 15 TC 2 Z9 3 U1 3 U2 17 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0894-9867 EI 1573-6598 J9 J TRAUMA STRESS JI J. Trauma Stress PD FEB PY 2014 VL 27 IS 1 BP 112 EP 115 DI 10.1002/jts.21883 PG 4 WC Psychology, Clinical; Psychiatry SC Psychology; Psychiatry GA AA7NR UT WOS:000331284600016 PM 24515537 ER PT J AU Negrea, C Thompson, DE Juhnke, SD Fryer, DS Loge, FJ AF Negrea, Cristi Thompson, Donald E. Juhnke, Steven D. Fryer, Derek S. Loge, Frank J. TI Automated Detection and Tracking of Adult Pacific Lampreys in Underwater Video Collected at Snake and Columbia River Fishways SO NORTH AMERICAN JOURNAL OF FISHERIES MANAGEMENT LA English DT Article AB To reduce staffing demands and enhance observational accuracy, we designed, implemented, and tested a computerized system for processing underwater video clips captured by static cameras and removing quiet frames in which no activity is detected. When the system detects activity, it tracks and counts the moving object. The implementation uses an adaptive background-subtraction algorithm for detection and motion prediction for tracking. The system can be used to reduce the amount of video that must be reviewed by personnel, and it can produce total fish passage counts through the monitored area. The automated system reduced the total number of video hours requiring review by an average of 87.5% for count window videos and 83.5% for videos of picketed leads and lamprey passage orifices. The software detected 98.6% of the 144 Pacific Lampreys Entosphenus tridentatus that were observed in 185h of raw video. Because the system is fully automated, monitoring requirements are negligible, and the cost reduction for fish monitoring is proportional to the number of quiet frames removed. Received March 27, 2013; accepted September 23, 2013 C1 [Negrea, Cristi; Thompson, Donald E.; Loge, Frank J.] Univ Calif Davis, Dept Civil & Environm Engn, Davis, CA 95616 USA. [Juhnke, Steven D.; Fryer, Derek S.] US Army Corps Engineers, Walla Walla, WA 99362 USA. RP Loge, FJ (reprint author), Univ Calif Davis, Dept Civil & Environm Engn, 1 Shields Ave, Davis, CA 95616 USA. EM fjloge@ucdavis.edu FU U.S. Army Corps of Engineers, Walla Walla District [W912EF-08-D-0007] FX This project was funded by the U.S. Army Corps of Engineers, Walla Walla District (Contract Number W912EF-08-D-0007). Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the supporting agency. William Abernathy (University of California, Davis) helped to prepare the manuscript. NR 21 TC 4 Z9 4 U1 0 U2 14 PU TAYLOR & FRANCIS INC PI PHILADELPHIA PA 520 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA SN 0275-5947 EI 1548-8675 J9 N AM J FISH MANAGE JI North Am. J. Fish Manage. PD FEB 1 PY 2014 VL 34 IS 1 BP 111 EP 118 DI 10.1080/02755947.2013.849634 PG 8 WC Fisheries SC Fisheries GA AB2CI UT WOS:000331600200010 ER PT J AU Filone, CM Caballero, IS Dower, K Mendillo, ML Cowley, GS Santagata, S Rozelle, DK Yen, J Rubins, KH Hacohen, N Root, DE Hensley, LE Connor, J AF Filone, Claire Marie Caballero, Ignacio S. Dower, Ken Mendillo, Marc L. Cowley, Glenn S. Santagata, Sandro Rozelle, Daniel K. Yen, Judy Rubins, Kathleen H. Hacohen, Nir Root, David E. Hensley, Lisa E. Connor, John TI The Master Regulator of the Cellular Stress Response (HSF1) Is Critical for Orthopoxvirus Infection SO PLOS PATHOGENS LA English DT Article ID HEAT-SHOCK RESPONSE; VACCINIA VIRUS-INFECTION; RNA INTERFERENCE SCREEN; GENE-EXPRESSION; MESSENGER-RNA; TRANSCRIPTION FACTOR-1; INTRACELLULAR MATURE; HSP90 INHIBITOR; HUMAN MONKEYPOX; CANCER-CELLS AB The genus Orthopoxviridae contains a diverse group of human pathogens including monkeypox, smallpox and vaccinia. These viruses are presumed to be less dependent on host functions than other DNA viruses because they have large genomes and replicate in the cytoplasm, but a detailed understanding of the host factors required by orthopoxviruses is lacking. To address this topic, we performed an unbiased, genome-wide pooled RNAi screen targeting over 17,000 human genes to identify the host factors that support orthopoxvirus infection. We used secondary and tertiary assays to validate our screen results. One of the strongest hits was heat shock factor 1 (HSF1), the ancient master regulator of the cytoprotective heat-shock response. In investigating the behavior of HSF1 during vaccinia infection, we found that HSF1 was phosphorylated, translocated to the nucleus, and increased transcription of HSF1 target genes. Activation of HSF1 was supportive for virus replication, as RNAi knockdown and HSF1 small molecule inhibition prevented orthopoxvirus infection. Consistent with its role as a transcriptional activator, inhibition of several HSF1 targets also blocked vaccinia virus replication. These data show that orthopoxviruses co-opt host transcriptional responses for their own benefit, thereby effectively extending their functional genome to include genes residing within the host DNA. The dependence on HSF1 and its chaperone network offers multiple opportunities for antiviral drug development. Author Summary Orthopoxviruses bring in many of the factors they need for replication and impair the host cell by preventing the expression of host proteins. Although orthopoxviruses are less reliant on the host than some viruses, host factors are still required for infection. Here, we report results from two genome-scale approaches that identify host proteins used by orthopoxviruses during infection. These approaches showed that the master regulator of the heat shock response, heat shock factor 1 (HSF1), is a critical host factor for orthopoxvirus replication. HSF1-regulated genes are some of the only host genes with expression maintained or increased following virus infection. Our studies show that orthopoxviruses enter the cell and activate a host transcription pathway as part of its own replication process. These proteins are then utilized by the virus during infection and packaged into the virion, essentially extending the viral genome to include genes co-opted from the host nuclear DNA. This is supported by the existence of heat shock proteins in the viral genome of non-orthopoxvirus genera. We further show that small-molecule inhibitors of HSF1 and HSF1-transcribed genes are effective inhibitors of orthopoxvirus replication, suggesting a new avenue for antiviral development. C1 [Filone, Claire Marie; Caballero, Ignacio S.; Dower, Ken; Rozelle, Daniel K.; Yen, Judy; Connor, John] Boston Univ, Sch Med, Dept Microbiol, Boston, MA 02118 USA. [Filone, Claire Marie; Hensley, Lisa E.] US Army, Med Res Inst Infect Dis, Div Virol, Ft Detrick, MD 21702 USA. [Mendillo, Marc L.; Santagata, Sandro; Rubins, Kathleen H.] Whitehead Inst Biomed Res, Cambridge, MA 02142 USA. [Cowley, Glenn S.; Hacohen, Nir; Root, David E.] Broad Inst, Cambridge, MA USA. RP Filone, CM (reprint author), Boston Univ, Sch Med, Dept Microbiol, Boston, MA 02118 USA. EM filone@bu.edu OI Rozelle, Dan/0000-0003-4158-6717; Connor, John/0000-0002-8867-7256 FU NIH R03 [MH094169-01]; SPARC from the Broad Institute [800050]; Postgraduate Research Participation Program; U.S. Army Research and Medical Command FX This work was funded by an NIH R03 (MH094169-01) and a SPARC grant (800050) from the Broad Institute. CMF was supported by the Postgraduate Research Participation Program and the U.S. Army Research and Medical Command administered by the Oak Ridge Institute for Science and Education (ORISE). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. NR 77 TC 6 Z9 6 U1 0 U2 7 PU PUBLIC LIBRARY SCIENCE PI SAN FRANCISCO PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA SN 1553-7374 J9 PLOS PATHOG JI PLoS Pathog. PD FEB PY 2014 VL 10 IS 2 AR e1003904 DI 10.1371/journal.ppat.1003904 PG 14 WC Microbiology; Parasitology; Virology SC Microbiology; Parasitology; Virology GA AB9CC UT WOS:000332085900051 PM 24516381 ER PT J AU Price, SC Williams, KS Beyer, FL AF Price, Samuel C. Williams, Kristen S. Beyer, Frederick L. TI Relationships between Structure and Alkaline Stability of Imidazolium Cations for Fuel Cell Membrane Applications SO ACS MACRO LETTERS LA English DT Article ID ANION-EXCHANGE MEMBRANES; POLYMER; CATALYSTS AB Anion exchange membranes have substantial potential to be useful in methanol fuel cells due to the viability of non-noble metal electrocatalysts at high pH and increases in the oxidation rate of methanol in alkaline conditions. However, long-term stability of the cationic moiety has been an issue, and imidazoliums have recently attracted attention as candidates for stable cations. The prevailing strategy for increasing the stability of the imidazolium has involved adding sterically hindering groups at the 2 position. Surprisingly, the findings of this study show that steric hindrance is the least effective strategy for stabilizing imidazoliums. We propose that the most important stabilizing factor for an imidazolium is the ability to provide alternative, reversible deprotonation reactions with hydroxide and outline other structure-property relationships for imidazolium cations. C1 [Price, Samuel C.; Williams, Kristen S.; Beyer, Frederick L.] US Army Res Lab, Weap & Mat Res Directorate, RDRL WMM G, Aberdeen Proving Ground, MD 21005 USA. RP Price, SC (reprint author), US Army Res Lab, Weap & Mat Res Directorate, RDRL WMM G, Bldg 4600, Aberdeen Proving Ground, MD 21005 USA. EM samuel.c.price7.ctr@mail.mil FU US Army Research Laboratory [ORISE 1120-1120-99] FX S.C.P. and K.S.W. were supported by the Postgraduate Research Participation Program at the US Army Research Laboratory, administered by the Oak Ridge Institute of Science and Education through an interagency agreement between the US Department of Energy and Army Research Laboratory (contract no. ORISE 1120-1120-99). NR 26 TC 36 Z9 36 U1 4 U2 58 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 2161-1653 J9 ACS MACRO LETT JI ACS Macro Lett. PD FEB PY 2014 VL 3 IS 2 BP 160 EP 165 DI 10.1021/mz4005452 PG 6 WC Polymer Science SC Polymer Science GA AB4QE UT WOS:000331774200009 ER PT J AU Irish, JL Sleath, A Cialone, MA Knutson, TR Jensen, RE AF Irish, Jennifer L. Sleath, Alison Cialone, Mary A. Knutson, Thomas R. Jensen, Robert E. TI Simulations of Hurricane Katrina (2005) under sea level and climate conditions for 1900 SO CLIMATIC CHANGE LA English DT Article ID TROPICAL CYCLONES; POTENTIAL IMPACT; STORM-SURGE; WIND FIELDS; NEW-ORLEANS; RISE; COASTAL; INTENSITY; RECONSTRUCTION AB Global warming may result in substantial sea level rise and more intense hurricanes over the next century, leading to more severe coastal flooding. Here, observed climate and sea level trends over the last century (c. 1900s to 2000s) are used to provide insight regarding future coastal inundation trends. The actual impacts of Hurricane Katrina (2005) in New Orleans are compared with the impacts of a similar hypothetical hurricane occurring c. 1900. Estimated regional sea level rise since 1900 of 0.75 m, which contains a dominant land subsidence contribution (0.57 m), serves as a 'prototype' for future climate-change induced sea level rise in other regions. Landform conditions c. 1900 were estimated by changing frictional resistance based on expected additional wetlands at lower sea levels. Surge simulations suggest that flood elevations would have been 15 to 60 % lower c. 1900 than the conditions observed in 2005. This drastic change suggests that significantly more flood damage occurred in 2005 than would have occurred if sea level and climate conditions had been like those c. 1900. We further show that, in New Orleans, sea level rise dominates surge-induced flooding changes, not only by increasing mean sea level, but also by leading to decreased wetland area. Together, these effects enable larger surges. Projecting forward, future global sea level changes of the magnitude examined here are expected to lead to increased flooding in coastal regions, even if the storm climate is unchanged. Such flooding increases in densely populated areas would presumably lead to more widespread destruction. C1 [Irish, Jennifer L.] Virginia Tech, Dept Civil & Environm Engn, Blacksburg, VA 24061 USA. [Sleath, Alison; Cialone, Mary A.; Jensen, Robert E.] US Army Engineer Coastal & Hydraul Lab, Vicksburg, MS 39180 USA. [Knutson, Thomas R.] NOAA, Geophys Fluid Dynam Lab, Princeton, NJ 08542 USA. RP Irish, JL (reprint author), Virginia Tech, Dept Civil & Environm Engn, Blacksburg, VA 24061 USA. EM jirish@vt.edu; alison.s.grzegorzewski@usace.army.mil; mary.a.cialone@usace.army.mil; tom.knutson@noaa.gov; robert.e.jensen@usace.army.mil OI Irish, Jennifer/0000-0002-2429-5953 FU U.S. Army Corps of Engineers; Virginia Tech; National Oceanic and Atmospheric Administration FX This work was funded by the U.S. Army Corps of Engineers, Virginia Tech, and the National Oceanic and Atmospheric Administration. The authors wish to thank C. Dietrich and colleagues for making FigureGen freely available for graphical display of ADCIRC results. NR 38 TC 2 Z9 2 U1 4 U2 45 PU SPRINGER PI DORDRECHT PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS SN 0165-0009 EI 1573-1480 J9 CLIMATIC CHANGE JI Clim. Change PD FEB PY 2014 VL 122 IS 4 BP 635 EP 649 DI 10.1007/s10584-013-1011-1 PG 15 WC Environmental Sciences; Meteorology & Atmospheric Sciences SC Environmental Sciences & Ecology; Meteorology & Atmospheric Sciences GA AB7MB UT WOS:000331973200009 ER PT J AU Ren, W Zhao, Q Swami, A AF Ren, Wei Zhao, Qing Swami, Ananthram TI Temporal Traffic Dynamics Improve the Connectivity of Ad Hoc Cognitive Radio Networks SO IEEE-ACM TRANSACTIONS ON NETWORKING LA English DT Article DE Ad hoc cognitive radio (CR) network; connectivity; continuum percolation; ergodicity; multihop delay; traffic dynamics ID SPECTRUM ACCESS AB In an ad hoc cognitive radio network, secondary users access channels temporarily unused by primary users, and the existence of a communication link between two secondary users depends on the transmitting and receiving activities of nearby primary users. Using theories and techniques from continuum percolation and ergodicity, we analytically characterize the connectivity of the secondary network defined in terms of the almost sure finiteness of the multihop delay, and show the occurrence of a phase transition phenomenon while studying the impact of the temporal dynamics of the primary traffic on the connectivity of the secondary network. Specifically, as long as the primary traffic has some temporal dynamics caused by either mobility and/or changes in traffic load and pattern, the connectivity of the secondary network depends solely on its own density and is independent of the primary traffic; otherwise, the connectivity of the secondary network requires putting a density-dependent cap on the primary traffic load. We show that the scaling behavior of the multihop delay depends critically on whether or not the secondary network is instantaneously connected. In particular, we establish the scaling law of the minimum multihop delay with respect to the source-destination distance when the propagation delay is negligible. C1 [Ren, Wei; Zhao, Qing] Univ Calif Davis, Dept Elect & Comp Engn, Davis, CA 95616 USA. [Swami, Ananthram] Army Res Lab, Adelphi, MD 20783 USA. RP Ren, W (reprint author), Univ Calif Davis, Dept Elect & Comp Engn, Davis, CA 95616 USA. EM qzhao@ece.ucdavis.edu FU Army Research Office [W911NF-08-1-0467]; National Science Foundation [CCF-0830685] FX Manuscript received January 24, 2011; revised April 29, 2012; accepted January 18, 2013; approved by IEEE/ACM TRANSACTIONS ON NETWORKING Editor V. Misra. Date of publication February 20, 2013; date of current version February 12, 2014. This work was supported in part by the Army Research Office under Grant W911NF-08-1-0467 and the National Science Foundation under Grant CCF-0830685. NR 22 TC 5 Z9 5 U1 0 U2 4 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1063-6692 EI 1558-2566 J9 IEEE ACM T NETWORK JI IEEE-ACM Trans. Netw. PD FEB PY 2014 VL 22 IS 1 BP 124 EP 136 DI 10.1109/TNET.2013.2244612 PG 13 WC Computer Science, Hardware & Architecture; Computer Science, Theory & Methods; Engineering, Electrical & Electronic; Telecommunications SC Computer Science; Engineering; Telecommunications GA AB7JV UT WOS:000331966900010 ER PT J AU Grzegorczyk, TM Barrowes, BE AF Grzegorczyk, Tomasz M. Barrowes, Benjamin E. TI Operation of the Pedemis Sensor at the Aberdeen Proving Ground Standardized Test Site: Single and Multi-Target Inversions SO IEEE GEOSCIENCE AND REMOTE SENSING LETTERS LA English DT Article DE Aberdeen Proving Ground (APG); dipole model; electromagnetic induction (EMI); Gauss-Newton iterative method; pedemis sensor; unexploded ordnance (UXO) ID ELECTROMAGNETIC INDUCTION SENSORS; UNEXPLODED ORDNANCE; IDENTIFICATION AB The Pedemis sensor is a newly designed electromagnetic induction sensor that exhibits the unique characteristics of: 1) being able to physically decouple its transmitter and receiver modules and 2) offering the possibility of dynamically selecting various data acquisition modes (individual selection of transmitters and selection of data acquisition time for shallow/deep target interrogation). Such flexibility is expected to be instrumental in non-trivial terrains exhibiting either an abundant vegetation or being highly contaminated by large or dense clutter. Before validating the sensor in such challenging configurations, however, the Pedemis was taken to Aberdeen Proving Ground, MD, for its first test site validation. This letter presents the protocol adopted for data acquisition as well as inversion results on typical targets, including inversion of semi-synthetic data with up to five simultaneous targets. C1 [Grzegorczyk, Tomasz M.] Delpsi LLC, Newton, MA 02458 USA. [Barrowes, Benjamin E.] US Army, Cold Reg Res & Engn Lab, Hanover, NH 03755 USA. RP Grzegorczyk, TM (reprint author), Delpsi LLC, Newton, MA 02458 USA. EM tomasz.grzegorczyk@delpsi.com FU Cold Regions Research and Engineering Laboratory, Engineer Research and Development Center, New Hampshire [W913E5-11-C-0014] FX This work was supported by the Cold Regions Research and Engineering Laboratory, Engineer Research and Development Center, New Hampshire under Contract W913E5-11-C-0014. NR 11 TC 1 Z9 1 U1 0 U2 5 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1545-598X EI 1558-0571 J9 IEEE GEOSCI REMOTE S JI IEEE Geosci. Remote Sens. Lett. PD FEB PY 2014 VL 11 IS 2 BP 394 EP 398 DI 10.1109/LGRS.2013.2263333 PG 5 WC Geochemistry & Geophysics; Engineering, Electrical & Electronic; Remote Sensing; Imaging Science & Photographic Technology SC Geochemistry & Geophysics; Engineering; Remote Sensing; Imaging Science & Photographic Technology GA AC0JS UT WOS:000332181200004 ER PT J AU Sherwood, D Sponsel, WE Lund, BJ Gray, W Watson, R Groth, SL Thoe, K Glickman, RD Reilly, MA AF Sherwood, Daniel Sponsel, William E. Lund, Brian J. Gray, Walt Watson, Richard Groth, Sylvia L. Thoe, Kimberly Glickman, Randolph D. Reilly, Matthew A. TI Anatomical Manifestations of Primary Blast Ocular Trauma Observed in a Postmortem Porcine Model SO INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE LA English DT Article DE trauma; blast impact; ultrabiomicroscopy (UBM); primary blast injury; histopathology ID BRAIN-INJURY; EYE INJURIES; SYSTEM; IMPACT; GLOBE; MECHANISMS; ORBIT; ENTITY; IRAQ; WAR AB PURPOSE. We qualitatively describe the anatomic features of primary blast ocular injury observed using a postmortem porcine eye model. Porcine eyes were exposed to various levels of blast energy to determine the optimal conditions for future testing. METHODS. We studied 53 enucleated porcine eyes: 13 controls and 40 exposed to a range of primary blast energy levels. Eyes were preassessed with B- scan and ultrasound biomicroscopy (UBM) ultrasonography, photographed, mounted in gelatin within acrylic orbits, and monitored with high- speed videography during blast- tube impulse exposure. Postimpact photography, ultrasonography, and histopathology were performed, and ocular damage was assessed. RESULTS. Evidence for primary blast injury was obtained. While some of the same damage was observed in the control eyes, the incidence and severity of this damage in exposed eyes increased with impulse and peak pressure, suggesting that primary blast exacerbated these injuries. Common findings included angle recession, internal scleral delamination, cyclodialysis, peripheral chorioretinal detachments, and radial peripapillary retinal detachments. No full-thickness openings of the eyewall were observed in any of the eyes tested. Scleral damage demonstrated the strongest associative tendency for increasing likelihood of injury with increased overpressure. CONCLUSIONS. These data provide evidence that primary blast alone (in the absence of particle impact) can produce clinically relevant ocular damage in a postmortem model. The blast parameters derived from this study are being used currently in an in vivo model. We also propose a new Cumulative Injury Score indicating the clinical relevance of observed injuries. C1 [Sherwood, Daniel; Sponsel, William E.; Watson, Richard; Glickman, Randolph D.; Reilly, Matthew A.] Univ Texas San Antonio, Dept Biomed Engn, San Antonio, TX 78249 USA. [Sponsel, William E.; Thoe, Kimberly] WESMD Profess Associates, San Antonio, TX USA. [Sponsel, William E.] UIW Rosenberg Sch Optometry, San Antonio, TX USA. [Lund, Brian J.] US Army Inst Surg Res, JBSA Ft Sam Houston, San Antonio, TX USA. [Gray, Walt] Univ Texas San Antonio, Dept Geol Sci, San Antonio, TX 78249 USA. [Watson, Richard] Biodynam Res Corp, San Antonio, TX USA. [Groth, Sylvia L.] Univ Minnesota, Sch Med, Minneapolis, MN 55455 USA. [Glickman, Randolph D.] Univ Texas Hlth Sci Ctr San Antonio, Dept Ophthalmol, San Antonio, TX 78229 USA. RP Reilly, MA (reprint author), Univ Texas San Antonio, Dept Biomed Engn, One UTSA Circle, San Antonio, TX 78249 USA. EM matthew.reilly@utsa.edu OI Reilly, Matthew/0000-0001-8029-0084 FU Department of Defense Vision Research Program [W81XWH-12-2-0055] FX Supported by the Department of Defense Vision Research Program, Award Number W81XWH-12-2-0055. The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense. William E. Sponsel is a PI with the Australian Research Council Centre of Excellence in Vision Science (ACEVS). NR 36 TC 6 Z9 6 U1 0 U2 7 PU ASSOC RESEARCH VISION OPHTHALMOLOGY INC PI ROCKVILLE PA 12300 TWINBROOK PARKWAY, ROCKVILLE, MD 20852-1606 USA SN 0146-0404 EI 1552-5783 J9 INVEST OPHTH VIS SCI JI Invest. Ophthalmol. Vis. Sci. PD FEB PY 2014 VL 55 IS 2 BP 1124 EP 1132 DI 10.1167/iovs.13-13295 PG 9 WC Ophthalmology SC Ophthalmology GA AB6IU UT WOS:000331891700060 PM 24474279 ER PT J AU Sweeney, SC Morefield, SW Weiss, CA Moser, RD Malone, PG Koenigstein, ML AF Sweeney, Steven C. Morefield, Sean W. Weiss, Charles A., Jr. Moser, Robert D. Malone, Philip G. Koenigstein, Michael L. TI Corrosion-Resistant Steel Fixtures for Masonry Walls in Military Buildings SO MATERIALS PERFORMANCE LA English DT Article AB The most common steel fixtures used in hollow-core masonry walls are wall ties that attach the brick veneer wall (outer wythe) to a concrete masonry wall or steel or wooden joists behind the wall. These fittings prevent wind pressure from deflecting the outer wythe, typically clay brick. Corrosion of the wall tie in the mortar can crack the mortar and weaken the wall. Corrosion of the wall tie or the bracket in the cavity between the wythes can detach the inner and outer components and make the outer wall vulnerable to wind damage. Tests of a new coating system for wall ties is underway at Fort Stewart, Georgia, and inspections of specially constructed wall sections and exposure tests conducted on the ties indicate that the vitreous enamel coating performs satisfactorily. C1 [Sweeney, Steven C.; Morefield, Sean W.; Weiss, Charles A., Jr.; Moser, Robert D.; Malone, Philip G.] US Army Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. [Koenigstein, Michael L.] Pro Perma Engn Coatings, Rolla, MO USA. RP Sweeney, SC (reprint author), US Army Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. FU Department of Defense Corrosion Prevention and Control Program (i.e., Office of Under Secretary of Defense, Office of Corrosion Policy and Oversight) FX The authors recognize the sponsors of the Department of Defense Corrosion Prevention and Control Program (i.e., Office of Under Secretary of Defense, Office of Corrosion Policy and Oversight [Director, Dan Dunmire], Deputy Assistant Secretary of the Army for Acquisition Policy and Logistics [Army Corrosion Control Prevention Executive, Wimpy D. Pybus], Assistant Chief of Staff for Installation Management [David Purcell], and Headquarters, U.S. Army Installation Management Command [Paul Volkman]). NR 16 TC 0 Z9 0 U1 1 U2 2 PU NATL ASSOC CORROSION ENG PI HOUSTON PA 1440 SOUTH CREEK DRIVE, HOUSTON, TX 77084-4906 USA SN 0094-1492 J9 MATER PERFORMANCE JI Mater. Perform. PD FEB PY 2014 VL 53 IS 2 BP 28 EP 33 PG 6 WC Materials Science, Characterization & Testing SC Materials Science GA AB1YM UT WOS:000331589900010 ER PT J AU Malone, PG Moser, RD Holton, SS Newman, JK Weiss, CA Morefield, SW AF Malone, Philip G. Moser, Robert D. Holton, Stacy S. Newman, J. Kent Weiss, Charles A., Jr. Morefield, Sean W. TI Limiting Corrosion Problems Related to Dust-Control Agents SO MATERIALS PERFORMANCE LA English DT Article AB A wide variety of materials have typically been available to prevent the production of dust from unpaved surfaces. Dust-control agents mixed with fine soil can remain on metal surfaces on and under vehicles and aircraft and in some cases can greatly accelerate corrosion. Tests with potassium lactobionate (K-LB) solutions showed that the compound was an effective retardant and could reduce the rate of corrosion to similar to 25% of the corrosion rate of the water-soil control, reducing corrosion rates below that seen with lactobionic acid. Research indicates that effective dust control can be produced with far less corrosion if organic humectants are used. C1 [Malone, Philip G.; Moser, Robert D.; Holton, Stacy S.; Newman, J. Kent; Weiss, Charles A., Jr.] US Army Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. [Morefield, Sean W.] US Army Engineer Res & Dev Ctr, Champaign, IL USA. RP Malone, PG (reprint author), US Army Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. NR 17 TC 0 Z9 0 U1 0 U2 2 PU NATL ASSOC CORROSION ENG PI HOUSTON PA 1440 SOUTH CREEK DRIVE, HOUSTON, TX 77084-4906 USA SN 0094-1492 J9 MATER PERFORMANCE JI Mater. Perform. PD FEB PY 2014 VL 53 IS 2 BP 50 EP 56 PG 7 WC Materials Science, Characterization & Testing SC Materials Science GA AB1YM UT WOS:000331589900015 ER PT J AU Clayton, JD AF Clayton, J. D. TI AN ALTERNATIVE THREE-TERM DECOMPOSITION FOR SINGLE CRYSTAL DEFORMATION MOTIVATED BY NON-LINEAR ELASTIC DISLOCATION SOLUTIONS SO QUARTERLY JOURNAL OF MECHANICS AND APPLIED MATHEMATICS LA English DT Article ID ANISOTROPIC CRYSTALS; EDGE DISLOCATION; PLASTICITY; ENERGY; MODEL; ELASTOPLASTICITY; POLYCRYSTALS; FRAMEWORK; PRESSURE; FRACTURE AB A new third term is incorporated within the multiplicative decomposition of the deformation gradient in the context of geometrically non-linear mechanics of defective elastic-plastic crystals. This enhanced description, when applied to an element of material of finite volume, accounts explicitly for average local residual lattice distortion due to defects within that volume. The magnitude of the distortion from this third term, determined analytically for an elastic cylindrical volume of outer radius R containing a single dislocation line threading its centre, is estimated as {[b/(pi R)](2) + f(2) + g(2)}(1/2), where b is Burgers vector magnitude, f accounts for elastic non-linearity, and g accounts for core effects. For a straight screw dislocation in a third-order isotropic elastic medium, at a dislocation density of 10 per cent of theoretical maximum, b/(pi R) is on the order of 0.1, f on the order of 0.01 and g is proportional to pressure exerted by the core and can be significant. Predictions of stresses and dislocation density under simple shear and uniaxial compression demonstrate differences from those of usual crystal plasticity at large strain and for high hardening. Besides offering a natural and precise delineation of contributions from dislocation velocity and dislocation generation to irreversible deformation, the three-term model allows for residual elastic strains-including dilatation observed in experiments and atomic simulations-not addressed by conventional two-term crystal plasticity. C1 US Army Res Lab, Aberdeen, MD USA. RP Clayton, JD (reprint author), US Army Res Lab, Aberdeen, MD USA. EM john.d.clayton1.civ@mail.mil RI Clayton, John/C-7760-2009 NR 45 TC 5 Z9 5 U1 0 U2 7 PU OXFORD UNIV PRESS PI OXFORD PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND SN 0033-5614 EI 1464-3855 J9 Q J MECH APPL MATH JI Q. J. Mech. Appl. Math. PD FEB PY 2014 VL 67 IS 1 BP 127 EP 158 DI 10.1093/qjmam/hbt026 PG 32 WC Mathematics, Applied; Mechanics SC Mathematics; Mechanics GA AB7ZE UT WOS:000332009100006 ER PT J AU Rivera, JC Glebus, GP Cho, MS AF Rivera, J. C. Glebus, G. P. Cho, M. S. TI Disability following combat-sustained nerve injury of the upper limb SO BONE & JOINT JOURNAL LA English DT Article ID OPERATION ENDURING FREEDOM; QUALITY-OF-LIFE; UPPER-EXTREMITY; IRAQI FREEDOM; NEUROPATHIC PAIN; TRAUMA; OUTCOMES; MANAGEMENT; PATIENT; WOUNDS AB Injuries to the limb are the most frequent cause of permanent disability following combat wounds. We reviewed the medical records of 450 soldiers to determine the type of upper limb nerve injuries sustained, the rate of remaining motor and sensory deficits at final follow-up, and the type of Army disability ratings granted. Of 189 soldiers with an injury of the upper limb, 70 had nerve-related trauma. There were 62 men and eight women with a mean age of 25 years (18 to 49). Disabilities due to nerve injuries were associated with loss of function, neuropathic pain or both. The mean nerve-related disability was 26% (0% to 70%), accounting for over one-half of this cohort's cumulative disability. Patients injured in an explosion had higher disability ratings than those injured by gunshot. The ulnar nerve was most commonly injured, but most disability was associated with radial nerve trauma. In terms of the final outcome, at military discharge 59 subjects (84%) experienced persistent weakness, 48 (69%) had a persistent sensory deficit and 17 (24%) experienced chronic pain from scar-related or neuropathic pain. Nerve injury was the cause of frequent and substantial disability in our cohort of wounded soldiers. C1 [Rivera, J. C.] San Antonio Mil Med Ctr, Ft Sam Houston, TX 78234 USA. US Army Inst Surg Res, Ft Sam Houston, TX 78234 USA. RP Rivera, JC (reprint author), San Antonio Mil Med Ctr, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA. EM jessica.cross@us.army.mil NR 24 TC 8 Z9 9 U1 1 U2 5 PU BRITISH EDITORIAL SOC BONE JOINT SURGERY PI LONDON PA 22 BUCKINGHAM STREET, LONDON WC2N 6ET, ENGLAND SN 2049-4394 J9 BONE JOINT J JI Bone Joint J. PD FEB PY 2014 VL 96B IS 2 BP 254 EP 258 PG 5 WC Orthopedics; Surgery SC Orthopedics; Surgery GA AA6PC UT WOS:000331219300018 PM 24493193 ER PT J AU Read, JA Cresce, AV Ervin, MH Xu, K AF Read, Jeffrey A. Cresce, Arthur V. Ervin, Matthew H. Xu, Kang TI Dual-graphite chemistry enabled by a high voltage electrolyte SO ENERGY & ENVIRONMENTAL SCIENCE LA English DT Article ID ELECTROCHEMICAL INTERCALATION; FLUORINATED ELECTROLYTES; ION BATTERY; CELLS AB A reversible dual-graphite intercalation chemistry with simultaneous accommodation of Li+ and PF6- in graphitic structures is enabled for the first time by a high voltage electrolyte based on a fluorinated solvent and additive, which is capable of supporting the chemistry at 5.2 V with high efficiency. This all-graphite battery promises an energy storage device of low cost, high safety and high environmental friendliness that are critical for large scale energy harvesting/storage needs. C1 [Read, Jeffrey A.; Cresce, Arthur V.; Ervin, Matthew H.; Xu, Kang] US Army Res Lab, Adelphi, MD 20783 USA. RP Read, JA (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM jeffrey.a.read4civ@mail.mil NR 17 TC 36 Z9 36 U1 20 U2 111 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 1754-5692 EI 1754-5706 J9 ENERG ENVIRON SCI JI Energy Environ. Sci. PD FEB PY 2014 VL 7 IS 2 BP 617 EP 620 DI 10.1039/c3ee43333a PG 4 WC Chemistry, Multidisciplinary; Energy & Fuels; Engineering, Chemical; Environmental Sciences SC Chemistry; Energy & Fuels; Engineering; Environmental Sciences & Ecology GA AA9KZ UT WOS:000331413700009 ER PT J AU Wang, HQ Steyer, GD Couvillion, BR Rybczyk, JM Beck, HJ Sleavin, WJ Meselhe, EA Allison, MA Boustany, RG Fischenich, CJ Rivera-Monroy, VH AF Wang, Hongqing Steyer, Gregory D. Couvillion, Brady R. Rybczyk, John M. Beck, Holly J. Sleavin, William J. Meselhe, Ehab A. Allison, Mead A. Boustany, Ronald G. Fischenich, Craig J. Rivera-Monroy, Victor H. TI Forecasting landscape effects of Mississippi River diversions on elevation and accretion in Louisiana deltaic wetlands under future environmental uncertainty scenarios SO ESTUARINE COASTAL AND SHELF SCIENCE LA English DT Article DE sediment diversion; surface elevation; vertical accretion; deltaic wetlands; sea-level rise; subsidence ID SEA-LEVEL RISE; COASTAL SALT MARSHES; VERTICAL ACCRETION; SEDIMENT TRANSPORT; SURFACE ELEVATION; SOIL FORMATION; LAND LOSS; RESTORATION; WATER; ESTUARY AB Large sediment diversions are proposed and expected to build new wetlands to alleviate the extensive wetland loss (5000 km(2)) affecting coastal Louisiana during the last 78 years. Current assessment and prediction of the impacts of sediment diversions have focused on the capture and dispersal of both water and sediment on the adjacent river side and the immediate outfall marsh area. However, little is known about the effects of sediment diversions on existing wetland surface elevation and vertical accretion dynamics in the receiving basin at the landscape scale. In this study, we used a spatial wetland surface elevation model developed in support of Louisiana's 2012 Coastal Master Plan to examine such landscape-scale effects of sediment diversions. Multiple sediment diversion projects were incorporated in the model to simulate surface elevation and vertical accretion for the next 50 years (2010-2060) under two environmental (moderate and less optimistic) scenarios. Specifically, we examined landscape-scale surface elevation and vertical accretion trends under diversions with different geographical locations, diverted discharge rates, and geomorphic characteristics of the receiving basin. Model results indicate that small diversions (<283 m(3) s(-1)) tend to have limited effects of reducing landscape-scale elevation loss (<3%) compared to a future without action (FWOA) condition. Large sediment diversions (>1500 m(3) s(-1)) are required to achieve landscape-level benefits to promote surface elevation via vertical accretion to keep pace with rising sea level. Published by Elsevier Ltd. C1 [Wang, Hongqing; Steyer, Gregory D.; Couvillion, Brady R.; Beck, Holly J.; Sleavin, William J.] US Geol Survey, Natl Wetlands Res Ctr, Baton Rouge, LA 70803 USA. [Rybczyk, John M.] Western Washington Univ, Dept Environm Sci, Bellingham, WA 98225 USA. [Meselhe, Ehab A.; Allison, Mead A.] Water Inst Guf, Baton Rouge, LA 70825 USA. [Allison, Mead A.] Tulane Univ, Dept Earth & Environm Sci, New Orleans, LA 70118 USA. [Boustany, Ronald G.] Nat Resources Conservat Serv, USDA, Lafayette, LA 70506 USA. [Fischenich, Craig J.] US Army Corps Engineers, Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. [Rivera-Monroy, Victor H.] Louisiana State Univ, Dept Oceanog & Coastal Sci, Sch Coast & Environm, Baton Rouge, LA 70803 USA. RP Wang, HQ (reprint author), US Geol Survey, Coastal Restorat Assessment Branch, Natl Wetlands Res Ctr, Livestock Show Off,LSU, Baton Rouge, LA 70803 USA. EM wangh@usgs.gov RI Allison, Mead/A-7208-2010; OI Wang, Hongqing/0000-0002-2977-7732 FU State of Louisiana's Coastal Protection and Restoration Authority (LaCPRA); NSF-Coupled Natural and Human Systems program [DBCS 1212112] FX This research was supported by funds from the State of Louisiana's Coastal Protection and Restoration Authority (LaCPRA) in support of Louisiana's 2012 Coastal Master Plan. We would like to thank Nadine Trahan, Yvonne Allen, Guerry Holm Jr., and Brian Perez for their assistance in model simulations and data analysis. We thank John Andrew Nyman as well as two anonymous reviewers for their constructive review for improving this manuscript. VHRM participation was partially supported by the NSF-Coupled Natural and Human Systems program under grant No. DBCS 1212112. Any use of trade, product, or firm names is for descriptive purposes only and does not imply endorsement by the U.S. Government. NR 50 TC 6 Z9 6 U1 5 U2 68 PU ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD PI LONDON PA 24-28 OVAL RD, LONDON NW1 7DX, ENGLAND SN 0272-7714 EI 1096-0015 J9 ESTUAR COAST SHELF S JI Estuar. Coast. Shelf Sci. PD FEB 1 PY 2014 VL 138 BP 57 EP 68 DI 10.1016/j.ecss.2013.12.020 PG 12 WC Marine & Freshwater Biology; Oceanography SC Marine & Freshwater Biology; Oceanography GA AB0VW UT WOS:000331511200006 ER PT J AU Romano, JM Rosario, D Niver, E AF Romano, Joao M. Rosario, Dalton Niver, Edip TI Morphological Operators for Polarimetric Anomaly Detection SO IEEE JOURNAL OF SELECTED TOPICS IN APPLIED EARTH OBSERVATIONS AND REMOTE SENSING LA English DT Article DE Anomaly detection; longwave infrared (LWIR); morphology; polarization; spectral polarimetric imagery collection experimentation (SPICE); termal ID MATHEMATICAL MORPHOLOGY; IMAGE CLASSIFICATION; SPATIAL-RESOLUTION; FEATURE-EXTRACTION; HYPERSPECTRAL DATA; TEXTURE FEATURES; TARGET DETECTION; TRANSFORMATIONS; PROFILES; SEGMENTATIONS AB We introduce an algorithm of morphological filters and propose its use to classic polarization metrics for applications requiring passive longwave-infrared, polarimetric remote sensing and real-time anomaly detection. The approach significantly augments the daytime and nighttime detectability of weak-signal manmade objects immersed in a predominant natural background scene. A tailored sequence of signal-enhancing filters is featured, consisting of basic and higher level morphological operators to achieve a desired goal. Qualitatively, the goal is to effectively squeeze the variance of pixel values representing the natural clutter background, while simultaneously spreading the pixel variance within the manmade object class and separating the pixel mean averages between the two classes of objects. Using real data, the approach persistently detected with a high confidence level three mobile military howitzer surrogates (targets) from natural clutter, during a 72-h coverage. Targets were posed at three aspect angles (range 557 m), yielding a negligible false alarm rate. Performance was invariant to diurnal cycle and mild atmospheric changes. C1 [Romano, Joao M.] US Army Armaments Res Dev & Engn ARDEC, Picatinny Arsenal, NJ 07806 USA. [Rosario, Dalton] US Army Res Lab ARL, Adelphi, MD 20783 USA. [Niver, Edip] New Jersey Inst Technol, Newark, NJ 07102 USA. RP Romano, JM (reprint author), US Army Armaments Res Dev & Engn ARDEC, Picatinny Arsenal, NJ 07806 USA. EM joao.m.romano@us.army.mil; dalton.s.rosario.civ@mail.mil; edip.niver@njit.edu FU U.S. Army ARDEC and Army Research Laboratory FX This work was supported by the U.S. Army ARDEC and Army Research Laboratory. NR 55 TC 7 Z9 8 U1 1 U2 16 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1939-1404 EI 2151-1535 J9 IEEE J-STARS JI IEEE J. Sel. Top. Appl. Earth Observ. Remote Sens. PD FEB PY 2014 VL 7 IS 2 BP 664 EP 677 DI 10.1109/JSTARS.2013.2271896 PG 14 WC Engineering, Electrical & Electronic; Geography, Physical; Remote Sensing; Imaging Science & Photographic Technology SC Engineering; Physical Geography; Remote Sensing; Imaging Science & Photographic Technology GA AB0BS UT WOS:000331457400024 ER PT J AU Hinojosa-Laborde, C Shade, RE Muniz, GW Bauer, C Goei, KA Pidcoke, HF Chung, KK Cap, AP Convertino, VA AF Hinojosa-Laborde, Carmen Shade, Robert E. Muniz, Gary W. Bauer, Cassondra Goei, Kathleen A. Pidcoke, Heather F. Chung, Kevin K. Cap, Andrew P. Convertino, Victor A. TI Validation of lower body negative pressure as an experimental model of hemorrhage SO JOURNAL OF APPLIED PHYSIOLOGY LA English DT Article DE blood loss; central hypovolemia; stroke volume; blood pressure; central venous pressure; cardiac output ID SYMPATHETIC-NERVE ACTIVITY; CENTRAL VENOUS-PRESSURE; COMBAT CASUALTY CARE; CENTRAL HYPOVOLEMIA; ARTERIAL-PRESSURE; CONSCIOUS RATS; MODERATE HEMORRHAGE; VASOPRESSIN RELEASE; ORTHOSTATIC STRESS; WATER RESTRICTION AB Lower body negative pressure (LBNP), a model of hemorrhage (Hem), shifts blood to the legs and elicits central hypovolemia. This study compared responses to LBNP and actual Hem in sedated baboons. Arterial pressure, pulse pressure (PP), central venous pressure (CVP), heart rate, stroke volume (SV), and +dP/dt were measured. Hem steps were 6.25%, 12.5%, 18.75%, and 25% of total estimated blood volume. Shed blood was returned, and 4 wk after Hem, the same animals were subjected to four LBNP levels which elicited equivalent changes in PP and CVP observed during Hem. Blood gases, hematocrit (Hct), hemoglobin (Hb), plasma renin activity (PRA), vasopressin (AVP), epinephrine (EPI), and norepinephrine (NE) were measured at baseline and maximum Hem or LBNP. LBNP levels matched with 6.25%, 12.5%, 18.75%, and 25% hemorrhage were -22 +/- 6, -41 +/- 7, -54 +/- 10, and -71 +/- 7 mmHg, respectively (mean +/- SD). Hemodynamic responses to Hem and LBNP were similar. SV decreased linearly such that 25% Hem and matching LBNP caused a 50% reduction in SV. Hem caused a decrease in Hct, Hb, and central venous oxygen saturation (ScvO(2)). In contrast, LBNP increased Hct and Hb, while ScvO(2) remained unchanged. Hem caused greater elevations in AVP and NE than LBNP, while PRA, EPI, and other hematologic indexes did not differ between studies. These results indicate that while LBNP does not elicit the same effect on blood cell loss as Hem, LBNP mimics the integrative cardiovascular response to Hem, and validates the use of LBNP as an experimental model of central hypovolemia associated with Hem. C1 [Hinojosa-Laborde, Carmen; Muniz, Gary W.; Pidcoke, Heather F.; Chung, Kevin K.; Cap, Andrew P.; Convertino, Victor A.] US Army Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Shade, Robert E.; Bauer, Cassondra] Texas Biomed Res Inst, San Antonio, TX USA. [Goei, Kathleen A.] Univ Incarnate Word, San Antonio, TX USA. [Chung, Kevin K.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA. RP Hinojosa-Laborde, C (reprint author), US Army Inst Surg Res, 3698 Chambers Pass, Ft Sam Houston, TX 78234 USA. EM carmen.hinojosa-laborde.civ@mail.mil FU United States Army, Medical Research and Materiel Command FX This study was funded by the United States Army, Medical Research and Materiel Command. NR 64 TC 21 Z9 21 U1 0 U2 1 PU AMER PHYSIOLOGICAL SOC PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 USA SN 8750-7587 EI 1522-1601 J9 J APPL PHYSIOL JI J. Appl. Physiol. PD FEB PY 2014 VL 116 IS 4 BP 406 EP 415 DI 10.1152/japplphysiol.00640.2013 PG 10 WC Physiology; Sport Sciences SC Physiology; Sport Sciences GA AA6NG UT WOS:000331214400006 PM 24356525 ER PT J AU Brozena, A Tevault, DE Irwin, K AF Brozena, Ann Tevault, David E. Irwin, Katherine TI Vapor Pressure of Thiodiglycol SO JOURNAL OF CHEMICAL AND ENGINEERING DATA LA English DT Article AB Thiodiglycol (TDG), also known as bis(2-hydroxyethyl) sulfide and thiodiethanol, is a precursor of the blister agent sulfur mustard (bis(2-chloroethyl) sulfide). It is also a hydrolytic degradation product, and as such, it is of considerable forensic interest to the chemical defense community. Experimental vapor pressure data have been reported previously for TDG at T = (283.15 to 353.15) K, in addition to reduced-pressure boiling points at T = (353.15 to 454.65) K. New data have been measured using two complementary American Society for Testing and Materials International methods at T = (417.75 to 538.58) K by differential scanning calorimetry and in the ambient temperature range using saturator methodology at T = (298.15 to 313.15) K. The new TDG vapor pressure data are in sharp contrast to widely accepted values from previous literature. C1 [Brozena, Ann; Tevault, David E.] US Army Res, Edgewood Chem Biol Ctr, Dev & Engn Command, Aberdeen Proving Ground, MD 21010 USA. [Irwin, Katherine] SRI Int, Menlo Pk, CA 94025 USA. RP Tevault, DE (reprint author), US Army Res, Edgewood Chem Biol Ctr, Dev & Engn Command, Aberdeen Proving Ground, MD 21010 USA. EM david.e.tevault.ctr@mail.mil NR 23 TC 4 Z9 4 U1 2 U2 5 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0021-9568 J9 J CHEM ENG DATA JI J. Chem. Eng. Data PD FEB PY 2014 VL 59 IS 2 BP 307 EP 311 DI 10.1021/je400978j PG 5 WC Thermodynamics; Chemistry, Multidisciplinary; Engineering, Chemical SC Thermodynamics; Chemistry; Engineering GA AB0OZ UT WOS:000331493300021 ER PT J AU Gilstrap, LG Niehaus, E Malhotra, R Ton, VK Watts, J Seldin, DC Madsen, JC Semigran, MJ AF Gilstrap, Lauren Gray Niehaus, Emily Malhotra, Rajeev Ton, Van-Khue Watts, James Seldin, David C. Madsen, Joren C. Semigran, Marc J. TI Predictors of survival to orthotopic heart transplant in patients with light chain amyloidosis SO JOURNAL OF HEART AND LUNG TRANSPLANTATION LA English DT Article DE light-chain cardiac amyloidosis; survival; orthotopic heart transplantation; body mass index; autologous stem cell transplant ID STEM-CELL TRANSPLANTATION; AL AMYLOIDOSIS; CARDIAC AMYLOIDOSIS; DISEASE; BORTEZOMIB; MELPHALAN; DEXAMETHASONE; COMBINATION; EXPERIENCE; FAILURE AB BACKGROUND: Orthotopic heart transplant (OHT), followed by myeloablative chemotherapy and autologous stem cell transplant (ASCT), has been successful in the treatment of amyloid light-chain (AL) cardiac amyloidosis. The purpose of this study was to identify predictors of survival to OHT in patients with end-stage heart failure due to AL amyloidosis and compare post-OHT survival of cardiac amyloid patients with survival of other cardiomyopathy patients undergoing OHT. METHODS: From January 2000 to June 2011, 31 patients with end-stage heart failure secondary to AL amyloidosis were listed for OHT at Massachusetts General Hospital. Univariate and multivariate regression analyses identified predictors of survival to OHT. Kaplan-Meier analysis compared survival between the Massachusetts General Hospital amyloidosis patients and non-amyloid cardiomyopathy patients from the Scientific Registry of Transplant Recipients (SRTR). RESULTS: Low body mass index was the only predictor of survival to OHT in patients with end-stage heart failure caused by cardiac amyloidosis. Survival of cardiac amyloid patients who died before receiving a donor heart was only 63 45 days after listing. Patients who survived to OHT received a donor organ at 53 48 days after listing. Survival of AL amyloidosis patients on the waiting list was less than patients on the waiting list for all other non-amyloid diagnoses. The Jong-term survival of amyloid patients who underwent OHT was no different than the survival of non-amyloid, restrictive (p = 0.34), non-amyloid dilated (p = 0.34), or all non-amyloid cardiomyopathy patients (p = 0.22) in the SRTR database. CONCLUSIONS: Amyloid patients who survive to OHT, followed by ASCT, have a survival rate similar to other cardiomyopathy patients undergoing OHT; however, 35% of the patients died awaiting OHT. The only predictor of survival to OHT in AL amyloidosis patients was a low body mass index, which correlated with a shorter time on the waiting list. To optimize the survival of these patients, access to donor organs must be improved. (C) 2014 International Society for Heart and Lung Transplantation. All rights reserved. C1 [Gilstrap, Lauren Gray; Niehaus, Emily; Malhotra, Rajeev; Semigran, Marc J.] Massachusetts Gen Hosp, Div Cardiol, Dept Med, Boston, MA 02114 USA. [Ton, Van-Khue] Johns Hopkins Med Inst, Dept Med, Div Cardiol, Baltimore, MD 21205 USA. [Watts, James] Brooke Army Med Ctr, Dept Med, Serv Cardiol, Ft Sam Houston, TX 78234 USA. [Seldin, David C.] Boston Univ, Med Ctr, Dept Med, Sect Hematol & Oncol,Ainyloidosis Ctr, Boston, MA USA. [Madsen, Joren C.] Massachusetts Gen Hosp, Div Cardiac Surg, Dept Surg, Boston, MA 02114 USA. RP Semigran, MJ (reprint author), Massachusetts Gen Hosp, Div Cardiol, Dept Med, Bigelow 800,55 Fruit St, Boston, MA 02114 USA. EM msemigran@partners.org OI Watts, James/0000-0003-1118-838X; Malhotra, Rajeev/0000-0003-0120-4630 FU American Heart Association [11FTF7290032] FX The authors acknowledge the efforts of Megan Borase, BA. R.M. received an American Heart Association Fellow to Faculty Award (#11FTF7290032). NR 33 TC 7 Z9 7 U1 0 U2 2 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 1053-2498 EI 1557-3117 J9 J HEART LUNG TRANSPL JI J. Heart Lung Transplant. PD FEB PY 2014 VL 33 IS 2 BP 149 EP 156 DI 10.1016/j.healun.2013.09.004 PG 8 WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery; Transplantation SC Cardiovascular System & Cardiology; Respiratory System; Surgery; Transplantation GA AA5SD UT WOS:000331159000007 ER PT J AU Pollio, HR Jensen, PR O'Neil, MA AF Pollio, Howard R. Jensen, Peter R. O'Neil, Michael A. TI The Semantics of Time and Space: A Thematic Analysis SO JOURNAL OF PSYCHOLINGUISTIC RESEARCH LA English DT Article DE Phenomenology; Time and space; Semantics; Metaphor AB Three empirical studies and one analysis of pre-existing data were performed to determine the everyday meanings of time, a major component of phenomenological analyses of human experience. To this end, participants in Studies 1 and 2 sorted time related words into groups having similar meanings, with these groups then evaluated by hierarchical clustering procedures. Results of Studies 1 and 2 produced similar clustering patterns suggesting it was possible to define the everyday meanings of time in terms of experiences of change and continuity, linear organization, tempo, and boundaries. Results of Study 3 indicated little or no effect on clustering patterns of time words when space words also were included in the set of items to be sorted. Concerns about the size and representativeness of the words used as stimuli in Studies 1, 2 and 3 led to an analysis of over 2,000 words falling under the general heading of Time in Roget's Thesaurus. Results of this analysis revealed that clusters comparable to those obtained in the other three studies also appeared in these data. These results were discussed in terms of their implications for the way in which "invisible" concepts such as time are thought about and used, particularly as related to figurative expression. C1 [Pollio, Howard R.] Univ Tennessee, Dept Psychol, Knoxville, TN 37996 USA. [Jensen, Peter R.] Univ Tennessee, Dept Kinesiol Recreat & Sport Studies, Knoxville, TN USA. [O'Neil, Michael A.] Univ Tennessee, Off Informat Technol, Knoxville, TN USA. RP Jensen, PR (reprint author), US Mil Acad, Ctr Enhanced Performance, 1st Floor Jefferson Hall,938 Cullum Rd, West Point, NY 10996 USA. EM pete8jensen@yahoo.com NR 20 TC 1 Z9 1 U1 0 U2 5 PU SPRINGER/PLENUM PUBLISHERS PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 0090-6905 EI 1573-6555 J9 J PSYCHOLINGUIST RES JI J. Psycholinguist. Res. PD FEB PY 2014 VL 43 IS 1 BP 81 EP 104 DI 10.1007/s10936-013-9242-x PG 24 WC Linguistics; Psychology, Experimental SC Linguistics; Psychology GA AA6HS UT WOS:000331200000006 PM 23479315 ER PT J AU Rokni, MR Widener, CA Champagne, VR AF Rokni, M. R. Widener, C. A. Champagne, V. R. TI Microstructural Evolution of 6061 Aluminum Gas-Atomized Powder and High-Pressure Cold-Sprayed Deposition SO JOURNAL OF THERMAL SPRAY TECHNOLOGY LA English DT Article DE aluminium; cold spraying; electron microscopy; microstructure; recrystallization ID GEOMETRIC DYNAMIC RECRYSTALLIZATION; INCIDENTAL DISLOCATION BOUNDARIES; MECHANICAL-PROPERTIES; GRAIN-BOUNDARIES; INTERFACIAL REGION; HIGH-VELOCITY; COATINGS; DEFORMATION; PARTICLES; ALLOY AB Gas-atomized 6061 aluminum powder was used as feedstock for deposition using a high pressure cold-spraying process. The microstructures of the as-received powder and cold spray processed (CSP) ultrafine-grained (UFG) 6061 depositions were characterized by different electron microscopy techniques. It was found that there is segregation of solute elements at the particle grain boundaries, which is increased after cold spraying (CS). Various microstructural features were observed in both directions (parallel and perpendicular) of the CSP layer, including low-angle grain boundaries, clustered-small-cell walls, and dislocation tangle zones. The results also indicated that a combination of different recrystallization mechanisms (i.e., continuous and geometrical) may contribute to the formation of nano and UFG structures during CS. C1 [Rokni, M. R.; Widener, C. A.] South Dakota Sch Mines Technol, Dept Mat & Met Engn, Rapid, SD 57701 USA. [Champagne, V. R.] US Army Res Lab, Weap & Mat Res Directorate, Aberdeen, MD USA. RP Rokni, MR (reprint author), South Dakota Sch Mines Technol, Dept Mat & Met Engn, Rapid, SD 57701 USA. EM mohammadreza.rokni@mines.sdsmt.edu FU Army Research Lab [W911NF-11-2-0014] FX This study was performed under subcontract to the Pueblo Economic Development Corporation (PEDCO) under Army Research Lab contract no. W911NF-11-2-0014. NR 37 TC 12 Z9 12 U1 0 U2 29 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1059-9630 EI 1544-1016 J9 J THERM SPRAY TECHN JI J. Therm. Spray Technol. PD FEB PY 2014 VL 23 IS 3 BP 514 EP 524 DI 10.1007/s11666-013-0049-y PG 11 WC Materials Science, Coatings & Films SC Materials Science GA AA3JV UT WOS:000330989600025 ER PT J AU Rickard, RF Martin, NAJ Lundy, JB AF Rickard, Rory F. Martin, Niall A. J. Lundy, Jonathan B. TI Imprecision in TBSA calculation SO BURNS LA English DT Letter ID BURNS; SYSTEM; AREA C1 [Rickard, Rory F.; Martin, Niall A. J.] Derriford Hosp, Dept Plast & Reconstruct Surg, Plymouth PL6 8DH, Devon, England. [Rickard, Rory F.] Royal Ctr Def Med, Acad Dept Mil Surg & Trauma, Birmingham, W Midlands, England. [Lundy, Jonathan B.] US Army Inst Surg Res, Ft Sam Houston, TX USA. RP Rickard, RF (reprint author), Derriford Hosp, Dept Plast & Reconstruct Surg, Plymouth PL6 8DH, Devon, England. EM roryrickard@nhs.net NR 6 TC 2 Z9 2 U1 1 U2 3 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0305-4179 EI 1879-1409 J9 BURNS JI Burns PD FEB PY 2014 VL 40 IS 1 BP 172 EP 173 DI 10.1016/j.burns.2013.09.002 PG 2 WC Critical Care Medicine; Dermatology; Surgery SC General & Internal Medicine; Dermatology; Surgery GA AA2EW UT WOS:000330908900028 PM 24075539 ER PT J AU Kugelman, JR Johnston, SC Mulembakani, PM Kisalu, N Lee, MS Koroleva, G McCarthy, SE Gestole, MC Wolfe, ND Fair, JN Schneider, BS Wright, LL Huggins, J Whitehouse, CA Wemakoy, EO Muyembe-Tamfum, JJ Hensley, LE Palacios, GF Rimoin, AW AF Kugelman, Jeffrey R. Johnston, Sara C. Mulembakani, Prime M. Kisalu, Neville Lee, Michael S. Koroleva, Galina McCarthy, Sarah E. Gestole, Marie C. Wolfe, Nathan D. Fair, Joseph N. Schneider, Bradley S. Wright, Linda L. Huggins, John Whitehouse, Chris A. Wemakoy, Emile Okitolonda Muyembe-Tamfum, Jean Jacques Hensley, Lisa E. Palacios, Gustavo F. Rimoin, Anne W. TI Genomic Variability of Monkeypox Virus among Humans, Democratic Republic of the Congo SO EMERGING INFECTIOUS DISEASES LA English DT Article ID ROCHE LIGHTCYCLER; SMALLPOX; INFECTION; TRANSMISSION; POXVIRUSES; SQUIRRELS; EVOLUTION; OUTBREAK; SEQUENCE; ECOLOGY AB Monkeypox virus is a zoonotic virus endemic to Central Africa. Although active disease surveillance has assessed monkeypox disease prevalence and geographic range, information about virus diversity is lacking. We therefore assessed genome diversity of viruses in 60 samples obtained from humans with primary and secondary cases of infection from 2005 through 2007. We detected 4 distinct lineages and a deletion that resulted in gene loss in 10 (16.7%) samples and that seemed to correlate with human-to-human transmission (p = 0.0544). The data suggest a high frequency of spillover events from the pool of viruses in nonhuman animals, active selection through genomic destabilization and gene loss, and increased disease transmissibility and severity. The potential for accelerated adaptation to humans should be monitored through improved surveillance. C1 [Kugelman, Jeffrey R.] US Army Med Res Inst Infect Dis, Ctr Genome Sci, Ft Detrick, MD USA. [Johnston, Sara C.; Lee, Michael S.; Koroleva, Galina; McCarthy, Sarah E.; Gestole, Marie C.; Huggins, John; Whitehouse, Chris A.; Palacios, Gustavo F.] US Army Med Res Inst Infect Dis, Ft Detrick, MD USA. [Mulembakani, Prime M.; Wemakoy, Emile Okitolonda] Kinshasa Sch Publ Hlth, Kinshasa, Zaire. [Kisalu, Neville; Rimoin, Anne W.] Univ Calif Los Angeles, Los Angeles, CA 90024 USA. [Wolfe, Nathan D.; Fair, Joseph N.; Schneider, Bradley S.] Global Viral Forecasting, San Francisco, CA USA. [Wright, Linda L.] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Bethesda, MD USA. [Muyembe-Tamfum, Jean Jacques] Natl Inst Biomed Res, Kinshasa, Zaire. [Hensley, Lisa E.] US FDA, Silver Spring, MD USA. RP Rimoin, AW (reprint author), Univ Calif Los Angeles, Fielding Sch Publ Hlth, Dept Epidemiol, 640 Charles E Young Dr S, Los Angeles, CA 90024 USA. EM gustavo.f.palacios.ctr@us.army.mil; arimoin@ucla.edu RI Palacios, Gustavo/I-7773-2015; OI Palacios, Gustavo/0000-0001-5062-1938; Schneider, Bradley S/0000-0001-7642-0018 FU Defense Threat Reduction Agency [1881290]; Metabiota; US Department of Defense Armed Forces Health Surveillance Center, Division of Global Emerging Infections, Surveillance Operations; Henry M. Jackson Foundation for the Advancement of Military Medicine; Defense Threat Reduction Agency Cooperative Biological Engagement Program; Google.org; Skoll Foundation; US Agency for International Development Emerging Pandemic Threats Program, PREDICT project [GHN-A-OO-09-00010-00] FX This work was funded by the Defense Threat Reduction Agency Project no. 1881290. The sample collection and epidemiologic study was partially financed by Metabiota, whose contribution was supported by the US Department of Defense Armed Forces Health Surveillance Center, Division of Global Emerging Infections, Surveillance Operations; the Henry M. Jackson Foundation for the Advancement of Military Medicine; the Defense Threat Reduction Agency Cooperative Biological Engagement Program; Google.org; the Skoll Foundation; and the US Agency for International Development Emerging Pandemic Threats Program, PREDICT project, under the terms of cooperative agreement no. GHN-A-OO-09-00010-00. NR 40 TC 9 Z9 9 U1 0 U2 9 PU CENTERS DISEASE CONTROL PI ATLANTA PA 1600 CLIFTON RD, ATLANTA, GA 30333 USA SN 1080-6040 EI 1080-6059 J9 EMERG INFECT DIS JI Emerg. Infect. Dis PD FEB PY 2014 VL 20 IS 2 BP 232 EP 239 DI 10.3201/eid2002.130118 PG 8 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA 301TA UT WOS:000330553800008 PM 24457084 ER PT J AU Garcia-Reyero, N Escalon, BL Prats, E Stanley, JK Thienpont, B Melby, NL Baron, E Eljarrat, E Barcelo, D Mestres, J Babin, PJ Perkins, EJ Raldua, D AF Garcia-Reyero, Natalia Escalon, B. Lynn Prats, Eva Stanley, Jacob K. Thienpont, Benedicte Melby, Nicolas L. Baron, Enrique Eljarrat, Ethel Barcelo, Damia Mestres, Jordi Babin, Patrick J. Perkins, Edward J. Raldua, Demetrio TI Effects of BDE-209 contaminated sediments on zebrafish development and potential implications to human health SO ENVIRONMENT INTERNATIONAL LA English DT Article DE Zebrafish; BDE-209; Microarrays; Behavior; Neurotoxicity; Acetylcholinesterase ID POLYBROMINATED DIPHENYL ETHERS; BROMINATED FLAME RETARDANTS; ADVERSE OUTCOME PATHWAYS; DECABROMODIPHENYL ETHER; CONCEPTUAL-FRAMEWORK; FATHEAD MINNOWS; RISK-ASSESSMENT; BREAST-MILK; EXPOSURE; FISH AB Polybrominated diphenyl ethers are compounds widely used as flame-retardants, which are of increasing environmental concern due to their persistence, and potential adverse effects. This study had two objectives. First we assessed if BDE-209 in sediment was bioavailable and bioaccumulated into zebrafish embryos. Secondly, we assessed the potential impact on human and environmental health of bioavailable BDE-209 using human in vitro cell assays and zebrafish embryos. Zebrafish were exposed from 4 h to 8 days post-fertilization to sediments spiked with 125 mg/kg of BDE-209. Zebrafish larvae accumulated ten fold more BDE-209 than controls in unspiked sediment after 8 days. BDE-209 impacted expression of neurological pathways and altered behavior of larvae, although BDE-209 had no visible affect on thyroid function or motoneuron and neuromast development. Zebrafish data and in silico predictions suggested that BDE-209 would also interact with key human transcription factors and receptors. We therefore tested these predictions using mammalian in vitro assays. BDE-209 activated human aryl hydrocarbon receptor, peroxisome proliferator activating receptors, CF/b-cat, activator protein I, Oct-MLP, and the estrogen receptor-related alpha (ERR alpha) receptor in cell-based assays. BDE-209 also inhibited human acetylcholinesterase activity. The observation that BDE-209 can be bioaccumulated from contaminated sediment highlights the need to consider this as a potential environmental exposure route. Once accumulated, our data also show that BDE-209 has the potential to cause impacts on both human and environmental health. (C) 2013 Elsevier Ltd. All rights reserved. C1 [Garcia-Reyero, Natalia] Mississippi State Univ, Inst Genom Biocomp & Biotechnol, Starkville, MS USA. [Escalon, B. Lynn; Stanley, Jacob K.; Melby, Nicolas L.; Perkins, Edward J.] US Army, Engineer Res & Dev Ctr, Environm Lab, Vicksburg, MS USA. [Prats, Eva] CID CSIC, Ctr Invest & Desarrollo, Barcelona, Catalonia, Spain. [Thienpont, Benedicte; Baron, Enrique; Eljarrat, Ethel; Barcelo, Damia; Raldua, Demetrio] IDAEA CSIC, Dept Environm Chem, Barcelona, Catalonia, Spain. [Mestres, Jordi] Univ Pompeu Fabra, IMIM Hosp del Mar, Chemotargets, Barcelona, Catalonia, Spain. [Babin, Patrick J.] Univ Bordeaux, Talence, France. RP Garcia-Reyero, N (reprint author), 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM nvinas@igbb.msstate.edu RI Mestres, Jordi/B-3673-2009; Prats, Eva/K-6434-2014; Raldua, Demetrio/K-6661-2014; Babin, Patrick/N-8794-2013; Gasull, Martina/A-6630-2013; OI Mestres, Jordi/0000-0002-5202-4501; Prats, Eva/0000-0001-7838-2027; Raldua, Demetrio/0000-0001-5256-1641; Barcelo, Damia/0000-0002-8873-0491; ELJARRAT, ETHEL/0000-0002-0814-6579 FU US Army Environmental Quality Research Program [BAA 11-4838]; Spanish MICINN [CTM2011-30471-C02-01] FX This work was partly funded by the US Army Environmental Quality Research Program (including BAA 11-4838). Permission for publishing this information has been granted by the Chief of Engineers. DR was supported by the Spanish MICINN grant CTM2011-30471-C02-01. The monoclonal antibodies znp-1, zn-8 antibodies (developed by B. Trevarrow) and SV2 (developed by K.M. Buckley) were obtained from the Developmental Studies Hybridoma Bank developed under the auspices of the NICHD and maintained by The University of Iowa, Department of Biology, Iowa City, IA 52242. NR 52 TC 15 Z9 15 U1 5 U2 54 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0160-4120 EI 1873-6750 J9 ENVIRON INT JI Environ. Int. PD FEB PY 2014 VL 63 BP 216 EP 223 DI 10.1016/j.envint.2013.11.012 PG 8 WC Environmental Sciences SC Environmental Sciences & Ecology GA AA2FG UT WOS:000330909900026 PM 24317228 ER PT J AU Ayithan, N Bradfute, SB Anthony, SM Stuthman, KS Dye, JM Bavari, S Bray, M Ozato, K AF Ayithan, Natarajan Bradfute, Steven B. Anthony, Scott M. Stuthman, Kelly S. Dye, John M. Bavari, Sina Bray, Mike Ozato, Keiko TI Ebola Virus-Like Particles Stimulate Type I Interferons and Proinflammatory Cytokine Expression Through the Toll-Like Receptor and Interferon Signaling Pathways SO JOURNAL OF INTERFERON AND CYTOKINE RESEARCH LA English DT Article ID PATTERN-RECOGNITION RECEPTORS; PLASMACYTOID DENDRITIC CELLS; INNATE IMMUNE-RESPONSES; MARBURG VIRUSES; ACTIVATION; INFECTION; VACCINE; MICE; GLYCOPROTEIN; MECHANISMS C1 [Ayithan, Natarajan; Ozato, Keiko] NICHHD, Program Genom Differentiat, NIH, Bethesda, MD 20892 USA. [Bradfute, Steven B.; Anthony, Scott M.; Stuthman, Kelly S.; Dye, John M.; Bavari, Sina] US Army, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA. [Bray, Mike] NIAID, Div Clin Res, NIH, Ft Detrick, MD USA. RP Ozato, K (reprint author), NICHHD, Program Genom Differentiat, NIH, Bldg 6,Ctr Dr,Room 2A01, Bethesda, MD 20892 USA. EM ozatok@nih.gov FU Intramural Program of NICHD; Trans-NIH FDA intramural Bio-defense Program, National Institutes of Health, USA FX This work was supported by the Intramural Program of NICHD and the Trans-NIH FDA intramural Bio-defense Program, National Institutes of Health, USA. The content of this publication does not necessarily reflect the views or policies of the US Department of Defense or the US Department of the Army. NR 56 TC 5 Z9 6 U1 1 U2 24 PU MARY ANN LIEBERT, INC PI NEW ROCHELLE PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA SN 1079-9907 EI 1557-7465 J9 J INTERF CYTOK RES JI J. Interferon Cytokine Res. PD FEB 1 PY 2014 VL 34 IS 2 BP 79 EP 89 PG 11 WC Biochemistry & Molecular Biology; Cell Biology; Immunology SC Biochemistry & Molecular Biology; Cell Biology; Immunology GA AA7PN UT WOS:000331289500002 PM 24102579 ER PT J AU Traversa, A Loffredo, E Gattullo, CE Palazzo, AJ Bashore, TL Senesi, N AF Traversa, Andreina Loffredo, Elisabetta Gattullo, Concetta E. Palazzo, Antonio J. Bashore, Terry L. Senesi, Nicola TI Comparative evaluation of compost humic acids and their effects on the germination of switchgrass (Panicum vigatum L.) SO JOURNAL OF SOILS AND SEDIMENTS LA English DT Article DE Compost humic acid; Fluorescence spectroscopy; FT IR spectroscopy; Germination and early growth effects; Switchgrass ID GROWTH; SUBSTANCES; PLANTS; SPECTROSCOPY AB This study aimed to investigate comparatively the main chemical and physico-chemical properties of the humic acid (HA) fraction of three different composts and to evaluate the bioactive effects of these HAs on the germination and early growth of four populations of switchgrass. Three compost HAs isolated from a green compost (HA(GC)), a mixed compost (HA(MC)), and a coffee compost (HA(CC)) were characterized for some chemical and physico-chemical properties, such as ash content, elemental composition, total acidity, carboxylic and phenolic OH group contents, E-4/E-6 ratio, Fourier Transform infrared (FT IR), and fluorescence spectroscopies. In subsequent experiments conducted in vitro in a climatic chamber under controlled conditions, the bioactive effects of the three HAs at concentrations of 10, 50, and 200 mg L-1 were tested on the germination and early growth of four switchgrass (Panicum virgatum L.) populations, the octaploids Shelter, Shawnee and Dacotah, and the tetraploid Alamo. The ash content and the E-4/E-6 ratio were, respectively, much higher or slightly higher for HA(CC) than for the other two HAs. HA(MC) showed the lowest C and H contents and the highest O content, whereas HA(GC) had the highest N content. The total acidity and phenolic OH group content followed the order: HA(MC) > HA(CC) > HA(GC). The fluorescence analysis of the three HAs evidenced a common fluorophore unit possibly associated to simple aromatic structures, such as phenolic-like, hydroxy-substituted benzoic and cinnamic acid derivatives. The FT IR spectra of all HA samples indicated the presence of aromatic phenolic structures. Significant beneficial effects were produced by any HA on switchgrass germination and early growth as a function of the population tested and the HA dose. Results of this study demonstrated that the addition of compost HAs to the germination medium of four switchgrass populations positively influenced the germination process and the growth of primary root and shoot. Significant correlations were found between HA bioactivity and some HA properties. These results suggest a possible use of compost as soil amendment in areas where switchgrass grows naturally or is cultivated. C1 [Traversa, Andreina; Loffredo, Elisabetta; Gattullo, Concetta E.; Senesi, Nicola] Univ Bari, Dipartimento Sci Suolo Pianta & Alimenti, I-70126 Bari, Italy. [Palazzo, Antonio J.] ERDC CRREL, Hanover, NH 03755 USA. [Bashore, Terry L.] HQ ACC A3A, Airfield Operat Div, Langley AFB, Hampton, VA USA. RP Loffredo, E (reprint author), Univ Bari, Dipartimento Sci Suolo Pianta & Alimenti, I-70126 Bari, Italy. EM elisabetta.loffredo@uniba.it OI Loffredo, Elisabetta/0000-0003-0783-5193 FU U.S. Army RDECOM ACQ CTR, Durham NC, USA [W911NF-08-1-0076]; Airspace, Ranges, and Airfield Operations Division, HQ Air Combat Command, Langley AFB, VA FX This work was supported by the Research Contract No. W911NF-08-1-0076 of the U.S. Army RDECOM ACQ CTR-W911NF, Durham NC, USA. Project title: Effects of quality composts and other organic amendments and their humic and fulvic acid fractions on the germination and early growth of slickspot Peppergrass (Lepidium papilliferum) and switchgrass in various experimental conditions, funded by the Airspace, Ranges, and Airfield Operations Division, HQ Air Combat Command, Langley AFB, VA. The opinions and conclusions in this article are those of the authors and do not necessarily reflect those of the U. S. Air Force, United States Army, or the Federal government. NR 27 TC 6 Z9 6 U1 3 U2 38 PU SPRINGER HEIDELBERG PI HEIDELBERG PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY SN 1439-0108 EI 1614-7480 J9 J SOIL SEDIMENT JI J. Soils Sediments PD FEB PY 2014 VL 14 IS 2 BP 432 EP 440 DI 10.1007/s11368-013-0653-y PG 9 WC Environmental Sciences; Soil Science SC Environmental Sciences & Ecology; Agriculture GA AA3AN UT WOS:000330965400021 ER PT J AU Tay, RY Griep, MH Mallick, G Tsang, SH Singh, RS Tumlin, T Teo, EHT Karna, SP AF Tay, Roland Yingjie Griep, Mark H. Mallick, Govind Tsang, Siu Hon Singh, Ram Sevak Tumlin, Travis Teo, Edwin Hang Tong Karna, Shashi P. TI Growth of Large Single-Crystalline Two-Dimensional Boron Nitride Hexagons on Electropolished Copper SO NANO LETTERS LA English DT Article DE Hexagonal boron nitride; atmospheric pressure chemical vapor deposition; scanning electron microscopy; atomic force microscopy ID CHEMICAL-VAPOR-DEPOSITION; THERMAL-DECOMPOSITION; GRAPHENE ELECTRONICS; BILAYER GRAPHENE; MONOLAYER; LAYER; HETEROSTRUCTURES; NUCLEATION; MORPHOLOGY; NANOSHEETS AB Hexagonal-boron nitride (h-BN) or "white graphene" has many outstanding properties including high thermal conductivity, high mechanical strength, chemical inertness, and high electrical resistance, which open up a wide range of applications such as thermal interface material, protective coatings, and dielectric in nanoelectronics that easily exceed the current advertised benefits pertaining to the graphene-based applications. The development of h-BN films using chemical vapor deposition (CVD) has thus far led into nucleation of triangular or asymmetric diamond shapes on different metallic surfaces. Additionally, the average size of the triangular domains has remained relatively small (similar to 0.5 mu m(2)) leading to a large number of grain boundaries and defects. While the morphology of Cu surfaces for CVD-grown graphene may have impacts on the nucleation density, domain sizes, thickness, and uniformity, the effects of the decreased roughness of Cu surface to develop h-BN films are unknown. Here, we report the growth and characterization of novel large area h-BN hexagons using highly electropolished Cu substrate under atmospheric pressure CVD conditions. We found that the nucleation density of h-BN is significantly reduced while domain sizes increase. In this study, the largest hexagonal-shape h-BN domain observed is 35 mu m(2), which is an order of magnitude larger than a typical triangular domain. As the domains coalesce to form a continuous film, the larger grain size offers a more pristine and smoother film with lesser grain boundaries induced defects. C1 [Tay, Roland Yingjie; Singh, Ram Sevak; Teo, Edwin Hang Tong] Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore 639798, Singapore. [Tay, Roland Yingjie; Mallick, Govind; Tsang, Siu Hon] Nanyang Technol Univ, Temasek Labs NTU, Singapore 639798, Singapore. [Griep, Mark H.; Mallick, Govind; Tumlin, Travis; Karna, Shashi P.] US Army Res Lab, Weap & Mat Res Directorate, Aberdeen, MD 21005 USA. [Teo, Edwin Hang Tong] Nanyang Technol Univ, Sch Mat Sci & Engn, Singapore 639798, Singapore. RP Teo, EHT (reprint author), Nanyang Technol Univ, Sch Elect & Elect Engn, 50 Nanyang Ave, Singapore 639798, Singapore. EM HTTEO@ntu.edu.sg RI Teo, Hang Tong Edwin/E-9437-2015 OI Teo, Hang Tong Edwin/0000-0003-0528-1764 FU MINDEF Singapore; Army Research Laboratory (ARL) U.S.A. FX The authors acknowledge the support from MINDEF Singapore and Army Research Laboratory (ARL) U.S.A. We are thankful to Dr. Eric Wetzel, Dr. Raymond Mackay, and Dr. Kristopher Behler of the U.S. Army Research Lab for their aid and input in the Cu surface morphology evaluation. NR 58 TC 71 Z9 71 U1 25 U2 248 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1530-6984 EI 1530-6992 J9 NANO LETT JI Nano Lett. PD FEB PY 2014 VL 14 IS 2 BP 839 EP 846 DI 10.1021/nl404207f PG 8 WC Chemistry, Multidisciplinary; Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter SC Chemistry; Science & Technology - Other Topics; Materials Science; Physics GA AA8KH UT WOS:000331343900068 PM 24447201 ER PT J AU Gist, NH Fedewa, MV Dishman, RK Cureton, KJ AF Gist, Nicholas H. Fedewa, Michael V. Dishman, Rod K. Cureton, Kirk J. TI Sprint Interval Training Effects on Aerobic Capacity: A Systematic Review and Meta-Analysis SO SPORTS MEDICINE LA English DT Review ID HUMAN SKELETAL-MUSCLE; ALL-CAUSE MORTALITY; TIME-TRIAL PERFORMANCE; CARDIORESPIRATORY FITNESS; METABOLIC ADAPTATIONS; PHYSICAL-FITNESS; LOW-VOLUME; INTENSITY EXERCISE; WOMEN; HEALTHY AB Background Sprint interval training (SIT) involving repeated 30-s "all out" efforts have resulted in significantly improved skeletal muscle oxidative capacity, maximal oxygen uptake, and endurance performance. The positive impact of SIT on cardiorespiratory fitness has far-reaching health implications. Objective The objective of this study was to perform a systematic review of the literature and meta-analysis to determine the effects of SIT on aerobic capacity. Methods A search of the literature was conducted using the key words 'sprint interval training', 'high intensity intermittent training/exercise', 'aerobic capacity', and 'maximal oxygen uptake'. Seventeen effects were analyzed from 16 randomized controlled trials of 318 participants. The mean +/- A standard deviation number of participants was 18.7 +/- A 5.1. Participant age was 23.5 +/- A 4.3 years. Results The effect size calculated for all studies indicates that supramaximal-intensity SIT has a small-to-moderate effect (Cohen's d = 0.32, 95 % CI 0.10-0.55; z = 2.79, P < 0.01) on aerobic capacity with an aggregate improvement of similar to 3.6 mL.kg(-1).min(-1) (similar to 8 % increase). The effect is moderate to large in comparison with no-exercise control groups (Cohen's d = 0.69, 95 % CI 0.46-0.93; z = 5.84, P < 0.01) and not different when compared with endurance training control groups (Cohen's d = 0.04, 95 % CI -0.17 to 0.24; z = 0.36, P = 0.72). Conclusion SIT improves aerobic capacity in healthy, young people. Relative to continuous endurance training of moderate intensity, SIT presents an equally effective alternative with a reduced volume of activity. This evaluation of effects and analysis of moderating variables consolidates the findings of small-sample studies and contributes to the practical application of SIT to improve cardiorespiratory fitness and health. C1 [Gist, Nicholas H.; Fedewa, Michael V.; Dishman, Rod K.; Cureton, Kirk J.] Univ Georgia, Dept Kinesiol, Athens, GA 30602 USA. [Gist, Nicholas H.] United States Mil Acad, Arvin Cadet Phys Dev Ctr, Dept Phys Educ, West Point, NY 10996 USA. RP Gist, NH (reprint author), United States Mil Acad, Arvin Cadet Phys Dev Ctr, Dept Phys Educ, 727 Brewerton Rd, West Point, NY 10996 USA. EM nicholas.gist@usma.edu NR 62 TC 45 Z9 47 U1 7 U2 90 PU ADIS INT LTD PI NORTHCOTE PA 5 THE WAREHOUSE WAY, NORTHCOTE 0627, AUCKLAND, NEW ZEALAND SN 0112-1642 EI 1179-2035 J9 SPORTS MED JI Sports Med. PD FEB PY 2014 VL 44 IS 2 BP 269 EP 279 DI 10.1007/s40279-013-0115-0 PG 11 WC Sport Sciences SC Sport Sciences GA AA3IH UT WOS:000330985600008 PM 24129784 ER PT J AU Corona, BT Ward, CL Baker, HB Walters, TJ Christ, GJ AF Corona, Benjamin T. Ward, Catherine L. Baker, Hannah B. Walters, Thomas J. Christ, George J. TI Implantation of In Vitro Tissue Engineered Muscle Repair Constructs and Bladder Acellular Matrices Partially Restore In Vivo Skeletal Muscle Function in a Rat Model of Volumetric Muscle Loss Injury SO TISSUE ENGINEERING PART A LA English DT Article ID EXTRACELLULAR-MATRIX; ECCENTRIC CONTRACTIONS; MURINE MODEL; STEM-CELLS; SATELLITE CELLS; REGENERATION; RECOVERY; SCAFFOLD; FIBROSIS; DEFECT C1 [Corona, Benjamin T.; Ward, Catherine L.; Baker, Hannah B.; Christ, George J.] Wake Forest Univ, Baptist Med Ctr, Wake Forest Inst Regenerat Med, Winston Salem, NC 27101 USA. [Corona, Benjamin T.; Ward, Catherine L.; Walters, Thomas J.] US Army Inst Surg Res, Dept Extrem Trauma & Regenerat Med, Ft Sam Houston, TX USA. RP Christ, GJ (reprint author), Wake Forest Univ, Baptist Med Ctr, Wake Forest Inst Regenerat Med, Richard H Dean Biomed Res Bldg,Room 257,391 Techn, Winston Salem, NC 27101 USA. EM gchrist@wakehealth.edu FU Armed Forces Institute for Regenerative Medicine [W81XWH-08-2-0032]; U.S. Army Medical Research and Medical Command [W81XWH-09-2-0177] FX We would like to thank Ms. Manasi Vadhavkar for her technical assistance during surgery and functional testing and Mr. Christopher Bergman for his technical assistance with histological procedures. The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or reflecting the views of the Department of Defense or the United States Government. The authors (btc, clw, and tjw) are employees of the U. S. government and this work was prepared as part of their official duties. This work was supported, in part, by the Armed Forces Institute for Regenerative Medicine (W81XWH-08-2-0032) and by the U.S. Army Medical Research and Medical Command (W81XWH-09-2-0177). NR 50 TC 38 Z9 40 U1 1 U2 21 PU MARY ANN LIEBERT, INC PI NEW ROCHELLE PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA SN 1937-3341 EI 1937-335X J9 TISSUE ENG PT A JI Tissue Eng. Part A PD FEB 1 PY 2014 VL 20 IS 3-4 BP 705 EP 715 PG 11 WC Cell & Tissue Engineering; Biotechnology & Applied Microbiology; Cell Biology SC Cell Biology; Biotechnology & Applied Microbiology GA AA6LC UT WOS:000331208800025 PM 24066899 ER PT J AU Taitt, CR Leski, TA Stockelman, MG Craft, DW Zurawski, DV Kirkup, BC Vora, GJ AF Taitt, Chris Rowe Leski, Tomasz A. Stockelman, Michael G. Craft, David W. Zurawski, Daniel V. Kirkup, Benjamin C. Vora, Gary J. TI Antimicrobial Resistance Determinants in Acinetobacter baumannii Isolates Taken from Military Treatment Facilities SO ANTIMICROBIAL AGENTS AND CHEMOTHERAPY LA English DT Article ID RIBOSOMAL-RNA METHYLASE; COMBAT-RELATED INJURIES; CARE SAFETY NETWORK; AMINOGLYCOSIDE-RESISTANCE; CALCOACETICUS COMPLEX; MULTIDRUG-RESISTANCE; MEDICAL-CENTER; PSEUDOMONAS-AERUGINOSA; QUINOLONE-RESISTANCE; CARBAPENEMASE GENES AB Multidrug-resistant (MDR) Acinetobacter baumannii infections are of particular concern within medical treatment facilities, yet the gene assemblages that give rise to this phenotype remain poorly characterized. In this study, we tested 97 clinical A. baumannii isolates collected from military treatment facilities (MTFs) from 2003 to 2009 by using a molecular epidemiological approach that enabled for the simultaneous screening of 236 antimicrobial resistance genes. Overall, 80% of the isolates were found to be MDR, each strain harbored between one and 17 resistant determinants, and a total of 52 unique resistance determinants or gene families were detected which are known to confer resistance to beta-lactam (e.g., blaGES-11, bla(TEM), bla(OXA-58)), aminoglycoside (e.g., aphA1, aacC1, armA), macrolide (msrA, msrB), tetracycline [e.g., tet(A), tet(B), tet(39)], phenicol (e.g., cmlA4, catA1, cat4), quaternary amine (qacE, qacE Delta 1), streptothricin (sat2), sulfonamide (sul1, sul2), and diaminopyrimidine (dfrA1, dfrA7, dfrA19) antimicrobial compounds. Importantly, 91% of the isolates harbored bla(OXA-51-like) carbapenemase genes (including six new variants), 40% harbored the blaOXA-23 carbapenemase gene, and 89% contained a variety of aminoglycoside resistance determinants with up to six unique determinants identified per strain. Many of the resistance determinants were found in potentially mobile gene cassettes; 45% and 7% of the isolates contained class 1 and class 2 integrons, respectively. Combined, the results demonstrate a facile approach that supports a more complete understanding of the genetic underpinnings of antimicrobial resistance to better assess the load, transmission, and evolution of MDR in MTF-associated A. baumannii. C1 [Taitt, Chris Rowe; Leski, Tomasz A.; Stockelman, Michael G.; Vora, Gary J.] Naval Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. [Craft, David W.; Zurawski, Daniel V.; Kirkup, Benjamin C.] Walter Reed Army Inst Res, Div Bacterial & Rickettsial Dis, Dept Wound Infect, Silver Spring, MD USA. [Kirkup, Benjamin C.] Uniformed Serv Univ Hlth Sci, Dept Med, Div Infect Dis, F Edward Hebert Sch Med, Bethesda, MD 20814 USA. RP Taitt, CR (reprint author), Naval Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. EM chris.taitt@nrl.navy.mil RI Leski, Tomasz/K-6916-2013; Kirkup, Benjamin/C-3610-2009; Chiang, Vincent, Ming-Hsien/D-4312-2016; OI Leski, Tomasz/0000-0001-7688-9887; Kirkup, Benjamin/0000-0002-8722-6218; Chiang, Vincent, Ming-Hsien/0000-0002-2029-7863; Zurawski, Daniel/0000-0002-7920-5601 FU Defense Medical Research and Development Program; Office of Naval Research FX This work was supported by the Defense Medical Research and Development Program and the Office of Naval Research. NR 75 TC 17 Z9 18 U1 1 U2 9 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA SN 0066-4804 EI 1098-6596 J9 ANTIMICROB AGENTS CH JI Antimicrob. Agents Chemother. PD FEB PY 2014 VL 58 IS 2 BP 767 EP 781 DI 10.1128/AAC.01897-13 PG 15 WC Microbiology; Pharmacology & Pharmacy SC Microbiology; Pharmacology & Pharmacy GA 302XD UT WOS:000330637500017 PM 24247131 ER PT J AU Waterman, BR Burns, TC McCriskin, B Kilcoyne, K Cameron, KL Owens, BD AF Waterman, Brian R. Burns, Travis C. McCriskin, Brendan Kilcoyne, Kelly Cameron, Kenneth L. Owens, Brett D. TI Outcomes After Bankart Repair in a Military Population: Predictors for Surgical Revision and Long-Term Disability SO ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY LA English DT Article ID RECURRENT SHOULDER DISLOCATION; ARTHROSCOPIC STABILIZATION; ANTERIOR; INSTABILITY; SURGEON; VOLUME; RECONSTRUCTION; ARTHROPLASTY; POSTERIOR; LESION AB Purpose: To quantify the rate of surgical failure after anterior shoulder stabilization procedures, as well as to identify demographic and surgical risk factors associated with poor outcomes. Methods: All Army patients undergoing arthroscopic or open Bankart repair for shoulder instability were isolated from the Military Health System Management Analysis and Reporting Tool between 2003 and 2010. Demographic variables (age, gender) and surgical variables (treatment facility volume, admission status, surgical technique) were extracted. Rates of surgical failure, defined as subsequent revision surgery or medical discharge with persistent shoulder complaints, were recorded from the electronic medical record and US Army Physical Disability Agency database. Risk factor analysis was performed with univariate t tests, chi 2 tests, and a multivariable logistic regression model with failure as the outcome. Results: A total of 3,854 patients underwent Bankart repair during the study period, with most procedures having been performed arthroscopically (n = 3,230, 84%) and on an outpatient basis (n = 3,255, 84%). Patients were predominately men (n = 3,531, 92%), and the mean age was 28.0 years (SD, 7.5 years). A total of 193 patients (5.0%) underwent revision stabilization whereas 339 patients (8.8%) were medically discharged with complaints of shoulder instability, for a total combined failure rate of 13.8% (n = 532). Univariate analyses showed no significant effect for gender; however, younger age, higher facility volume, open repair, and inpatient status were significant factors associated with subsequent surgical failure. Multivariable analyses confirmed that young age (odds ratio [OR], 0.93; 95% confidence interval [CI], 0.91 to 0.96; P <.001), open repair (OR, 0.52; 95% CI, 0.36 to 0.75; P = .001), and inpatient status (OR, 0.58; 95% CI, 0.40 to 0.84; P = .004) were independently associated with failure by revision surgery. Conclusions: Young age remains a significant risk factor for surgical failure after Bankart repair. Patients who underwent arthroscopic Bankart repair had a significantly lower surgical failure rate (4.5%) than patients who underwent open anterior stabilization (7.7%). Despite advances in surgical technique, 1 in 20 military service members required revision surgery after failed primary stabilization in this study. Level of Evidence: Level IV, therapeutic case series. C1 [Waterman, Brian R.; McCriskin, Brendan] William Beaumont Army Med Ctr, Dept Orthopaed Surg & Rehabil, El Paso, TX 79920 USA. [Burns, Travis C.; Cameron, Kenneth L.; Owens, Brett D.] US Mil Acad, Keller Army Hosp, West Point, NY USA. [Kilcoyne, Kelly] Walter Reed Mil Med Ctr, Bethesda, MD USA. RP Owens, BD (reprint author), Keller Army Hosp, Orthopaed Surg Serv, 5005 N Piedras St, West Point, NY 10996 USA. EM b.owens@us.army.mil OI Cameron, Kenneth/0000-0002-6276-4482 NR 28 TC 11 Z9 11 U1 0 U2 0 PU W B SAUNDERS CO-ELSEVIER INC PI PHILADELPHIA PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA SN 0749-8063 EI 1526-3231 J9 ARTHROSCOPY JI Arthroscopy PD FEB PY 2014 VL 30 IS 2 BP 172 EP 177 DI 10.1016/j.arthro.2013.11.004 PG 6 WC Orthopedics; Surgery SC Orthopedics; Surgery GA 301ZQ UT WOS:000330571400008 PM 24485110 ER PT J AU Pankow, M Quabili, A Yen, CF AF Pankow, Mark Quabili, Ashiq Yen, Chian-Fong TI Hybrid Three-Dimensional (3-D) Woven Thick Composite Architectures in Bending SO JOM LA English DT Article ID SANDWICH COMPOSITES; BEHAVIOR; MECHANISMS; PROPERTY; FAILURE AB In this study, three 3-dimensional (3-D) woven composite materials were examined to determine how yarn tow configurations affect the flexural response of the structure. Woven fabric preforms were manufactured with a Z-fiber architecture in 2-3 in. thicknesses. These preforms contained S-2 Glass (AGY, Aiken, SC, USA), carbon, and Twaron (Teijin Aramid, Arnhem, The Netherlands) yarns in different architectures creating a hybrid material system. Due to the thickness of the material, these samples required a significant span length (30 in.). The results showed a change in the strength and degradation after failure with the addition of carbon layers in tension. C1 [Pankow, Mark] N Carolina State Univ, Raleigh, NC 27695 USA. [Quabili, Ashiq; Yen, Chian-Fong] Army Res Lab, Aberdeen, MD USA. RP Pankow, M (reprint author), N Carolina State Univ, Raleigh, NC 27695 USA. EM mrpankow@ncsu.edu FU ARL FX The authors would like to thank ARL for their continued financial support. NR 15 TC 0 Z9 0 U1 0 U2 14 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1047-4838 EI 1543-1851 J9 JOM-US JI JOM PD FEB PY 2014 VL 66 IS 2 BP 255 EP 260 DI 10.1007/s11837-013-0825-7 PG 6 WC Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering; Mineralogy; Mining & Mineral Processing SC Materials Science; Metallurgy & Metallurgical Engineering; Mineralogy; Mining & Mineral Processing GA 304FR UT WOS:000330733000012 ER PT J AU Holmes, LR Riddick, JC AF Holmes, Larry R., Jr. Riddick, Jaret C. TI Research Summary of an Additive Manufacturing Technology for the Fabrication of 3D Composites with Tailored Internal Structure SO JOM LA English DT Article ID POLYMERIC COMPOSITES; ELECTRIC-FIELD AB A novel additive manufacturing technology is used to create micro-composites, which can be tailored for specific end-use applications. The Field-Aided Laminar Composite (FALCom) process uses specifically focused electric fields to align nano- to micro-sized particles into chain-like structures, which are referred to as pseudo-fibers. These pseudo-fibers are then immediately frozen into place by incident ultraviolet radiation on the photopolymer matrix. The pseudo-fibers are arranged by design, and they are used to create three-dimensional composite structures. Multiple filler materials have been evaluated for use in the FALCom system; however, this report describes aluminum micro-particles that are aligned and oriented in an acrylic photopolymer matrix. A description of the technology and a review of experimental processing are shown, and conclusions, as well as, future work are discussed. C1 [Holmes, Larry R., Jr.] US Army Res Lab, MiCRO Lab, Aberdeen Proving Ground, MD 21005 USA. [Riddick, Jaret C.] US Army Res Lab, Vehicle Technol Directorate, Aberdeen, MD 21005 USA. RP Holmes, LR (reprint author), US Army Res Lab, MiCRO Lab, Aberdeen Proving Ground, MD 21005 USA. EM larry.r.holmes.civ@mail.mil; jarer.c.riddick.civ@mail.mil NR 22 TC 5 Z9 5 U1 4 U2 58 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1047-4838 EI 1543-1851 J9 JOM-US JI JOM PD FEB PY 2014 VL 66 IS 2 BP 270 EP 274 DI 10.1007/s11837-013-0828-4 PG 5 WC Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering; Mineralogy; Mining & Mineral Processing SC Materials Science; Metallurgy & Metallurgical Engineering; Mineralogy; Mining & Mineral Processing GA 304FR UT WOS:000330733000014 ER PT J AU Prasad, KE Li, B Dixit, N Shaffer, M Mathaudhu, SN Ramesh, KT AF Prasad, K. Eswar Li, B. Dixit, N. Shaffer, M. Mathaudhu, S. N. Ramesh, K. T. TI The Dynamic Flow and Failure Behavior of Magnesium and Magnesium Alloys SO JOM LA English DT Article ID CHANNEL ANGULAR EXTRUSION; MG AZ31 SHEET; STRAIN RATES; DEFORMATION MECHANISMS; ROOM-TEMPERATURE; PLASTIC-DEFORMATION; TEXTURE EVOLUTION; GRAIN-REFINEMENT; CRYSTALLOGRAPHIC TEXTURE; CONSTITUTIVE RELATIONS AB We review the dynamic behavior of magnesium alloys through a survey of the literature and a comparison with our own high-strain-rate experiments. We describe high-strain-rate experiments (at typical strain rates of 10(3) s(-1)) on polycrystalline pure magnesium as well as two magnesium alloys, AZ31B and ZK60. Both deformation and failure are considered. The observed behaviors are discussed in terms of the fundamental deformation and failure mechanisms in magnesium, considering the effects of grain size, strain rate, and crystallographic texture. A comparison of current results with the literature studies on these and other Mg alloys reveals that the crystallographic texture, grain size, and alloying elements continue to have a profound influence on the high-strain-rate deformation behavior. The available data set suggests that those materials loaded so as to initiate extension twinning have relatively rate-insensitive strengths up to strain rates of several thousand per second. In contrast, some rate dependence of the flow stress is observed for loading orientations in which the plastic flow is dominated by dislocation mechanisms. C1 [Prasad, K. Eswar; Shaffer, M.; Ramesh, K. T.] Johns Hopkins Univ, Hopkins Extreme Mat Inst, Baltimore, MD 21218 USA. [Li, B.] Mississippi State Univ, Ctr Adv Vehicular Syst, Starkville, MS 39762 USA. [Dixit, N.; Ramesh, K. T.] Johns Hopkins Univ, Dept Mech Engn, Baltimore, MD 21218 USA. [Mathaudhu, S. N.] US Army Res Off, Div Mat Sci, Res Triangle Pk, NC 27709 USA. RP Prasad, KE (reprint author), Johns Hopkins Univ, Hopkins Extreme Mat Inst, Baltimore, MD 21218 USA. EM ramesh@jhu.edu RI Mathaudhu, Suveen/B-4192-2009 FU Army Research Laboratory under the MEDE Collaborative Research Alliance [W911NF-12-2-0022] FX This research was performed within the Center for Materials in Extreme Dynamic Environments (CMEDE) under the Hopkins Extreme Materials Institute at Johns Hopkins University. The work was funded by the Army Research Laboratory under the MEDE Collaborative Research Alliance, through Grant W911NF-12-2-0022. Professors Ibrahim Karaman and K. Ted Hartwig of Texas A&M University are also thanked for providing processing expertise and providing the ECAE processed AZ31B samples used in this study. NR 70 TC 16 Z9 16 U1 2 U2 34 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1047-4838 EI 1543-1851 J9 JOM-US JI JOM PD FEB PY 2014 VL 66 IS 2 BP 291 EP 304 DI 10.1007/s11837-013-0850-6 PG 14 WC Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering; Mineralogy; Mining & Mineral Processing SC Materials Science; Metallurgy & Metallurgical Engineering; Mineralogy; Mining & Mineral Processing GA 304FR UT WOS:000330733000017 ER PT J AU Fritz, JM Thackeray, A Brennan, GP Childs, JD AF Fritz, Julie M. Thackeray, Anne Brennan, Gerard P. Childs, John D. TI Exercise Only, Exercise With Mechanical Traction, or Exercise With Over-Door Traction for Patients With Cervical Radiculopathy, With or Without Consideration of Status on a Previously Described Subgrouping Rule: A Randomized Clinical Trial SO JOURNAL OF ORTHOPAEDIC & SPORTS PHYSICAL THERAPY LA English DT Article DE neck; nerve roots; spine ID CHRONIC NECK PAIN; DISABILITY-INDEX; THERAPY; EFFICACY; CLASSIFICATION; RELIABILITY; MANAGEMENT; DISORDERS; OUTCOMES; FUSION AB STUDY DESIGN: Randomized clinical trial. OBJECTIVES: To examine the effectiveness of cervical traction in addition to exercise for specific subgroups of patients with neck pain. BACKGROUND: Cervical traction is frequently used, but its effectiveness has not been adequately examined. Existing studies have failed to target patients most likely to respond. Traction is typically recommended for patients with cervical radiculopathy. A prediction rule has been described to identify a narrower subgroup of patients likely to respond to cervical traction. METHODS: Patients with neck pain and signs of radiculopathy were randomized to 4 weeks of treatment with exercise, exercise with mechanical traction, or exercise with over-door traction. Baseline assessment included subgrouping-rule status. The primary outcome measure (Neck Disability Index, scored 0-100) and secondary outcome measure (neck and arm pain intensity) were assessed at 4 weeks, 6 months, and 12 months after enrollment. The primary analyses examined 2-way treatment-by-time interactions. Secondary analyses examined validity of the subgrouping rule by adding 3-way interactions. RESULTS: Eighty-six patients (53.5% female; mean age, 46.9 years) were enrolled in the study. Intention-to-treat analysis found lower Neck Disability Index scores at 6 months in the mechanical traction group compared to the exercise group (mean difference between groups, 13.3; 95% confidence interval: 5.6, 21.0) and over-door traction group (mean difference between groups, 8.1; 95% confidence interval: 0.8, 15.3), and at 12 months in the mechanical traction group compared to the exercise group (mean difference between groups, 9.8; 95% confidence interval: 0.2, 19.4). Secondary outcomes favored mechanical traction at several time points. The validity of the subgrouping rule was supported on the Neck Disability Index at the 6-month time point only. CONCLUSION: Adding mechanical traction to exercise for patients with cervical radiculopathy resulted in lower disability and pain, particularly at long-term follow-ups. C1 [Fritz, Julie M.; Thackeray, Anne] Univ Utah, Dept Phys Therapy, Salt Lake City, UT USA. [Fritz, Julie M.; Brennan, Gerard P.] Intermt Healthcare, Salt Lake City, UT USA. [Childs, John D.] US Army Baylor Univ, Doctoral Program Phys Therapy, San Antonio, TX USA. RP Fritz, JM (reprint author), 520 Wakara Way, Salt Lake City, UT 84106 USA. EM julie.fritz@utah.edu OI Thackeray, Anne/0000-0002-5496-7730 FU Intermountain Healthcare; University of Utah, and Wilford Hall Medical Center FX The authors acknowledge the support and assistance of the physical therapists at Intermountain Healthcare, the University of Utah, and Wilford Hall Medical Center for their support and contributions toward completing this study. NR 53 TC 12 Z9 14 U1 2 U2 20 PU J O S P T, PI ALEXANDRIA PA 1111 NORTH FAIRFAX ST, STE 100, ALEXANDRIA, VA 22314-1436 USA SN 0190-6011 J9 J ORTHOP SPORT PHYS JI J. Orthop. Sports Phys. Ther. PD FEB PY 2014 VL 44 IS 2 BP 45 EP 57 DI 10.2519/jospt.2014.5065 PG 13 WC Orthopedics; Rehabilitation; Sport Sciences SC Orthopedics; Rehabilitation; Sport Sciences GA 304KZ UT WOS:000330747100002 PM 24405257 ER PT J AU Shepard, NP Westrick, RB Johnson, MR AF Shepard, Nathan P. Westrick, Richard B. Johnson, Michael R. TI Fractures Through the Base of the Second and Third Metacarpals SO JOURNAL OF ORTHOPAEDIC & SPORTS PHYSICAL THERAPY LA English DT Editorial Material C1 [Shepard, Nathan P.; Westrick, Richard B.; Johnson, Michael R.] US Army Baylor Univ Sports Phys Therapy Doctoral, Keller Army Community Hosp, West Point, NY 10996 USA. RP Shepard, NP (reprint author), US Army Baylor Univ Sports Phys Therapy Doctoral, Keller Army Community Hosp, West Point, NY 10996 USA. NR 3 TC 0 Z9 0 U1 0 U2 0 PU J O S P T, PI ALEXANDRIA PA 1111 NORTH FAIRFAX ST, STE 100, ALEXANDRIA, VA 22314-1436 USA SN 0190-6011 J9 J ORTHOP SPORT PHYS JI J. Orthop. Sports Phys. Ther. PD FEB PY 2014 VL 44 IS 2 BP 129 EP 129 DI 10.2519/jospt.2014.0403 PG 1 WC Orthopedics; Rehabilitation; Sport Sciences SC Orthopedics; Rehabilitation; Sport Sciences GA 304KZ UT WOS:000330747100011 PM 24484413 ER PT J AU Swab, JJ Pavlacka, R Gilde, G Kilczewski, S Wright, J Harris, D AF Swab, Jeffrey J. Pavlacka, Robert Gilde, Gary Kilczewski, Steve Wright, Jared Harris, Donovan TI Determining the Strength of Coarse-Grained AlON and Spinel SO JOURNAL OF THE AMERICAN CERAMIC SOCIETY LA English DT Article ID MAGNESIUM ALUMINATE SPINEL; ROOM-TEMPERATURE; MGAL2O4; OXYNITRIDE; CERAMICS AB The strength of two coarse-grained (grain size>200m) cubic ceramics, a magnesium aluminate spinel (MgAl2O4) and an AlON , along with a fine-grained (1.5m) MgAl2O4, was determined by conducting a series of four-point and equibiaxial flexure tests on specimens of different sizes. Weibull strength size scaling revealed a linear relationship on a log-log plot between average flexure strength and effective specimen area for the fine-grained spinel, but a nonlinear relationship for both coarse-grained materials. Initial fractography showed that each material had a single flaw population limiting the strength over the entire specimen size range, which does not account for the nonlinear size scaling relationship in the two coarse-grained materials. However, further fractography revealed that in both materials there was an initial flaw and a critical flaw. The former appears to be machining/polishing damage that started the fracture process while the latter was a cleaved grain in AlON or a cracked grain boundary in the HP/HIP spinel that lead to fracture of the specimen. The difference between the initial and critical flaw size coupled with a detailed analysis of the strength as a function of test specimen thickness accounted for the nonlinear strength size scaling relationship. As a result, strength values obtained using thin test specimens can lead to an erroneous strength prediction for large components made of these ceramics. The implication of these findings is that strength tests must be conducted using appropriately thick specimens to obtain a representative strength value. If appropriately thick specimens cannot be tested, then fractography must be conducted to determine the flaw size. If the flaw size is sufficiently large, compared with the specimen thickness, then the strength must be adjusted according to a stress field correction factor to obtain a more accurate strength value. C1 [Swab, Jeffrey J.; Pavlacka, Robert; Gilde, Gary; Kilczewski, Steve; Wright, Jared; Harris, Donovan] US Army Res Lab, Mat & Mfg Sci Div, Ceram & Transparent Mat Branch, Aberdeen, MD 21005 USA. [Pavlacka, Robert] Oak Ridge Inst Sci & Educ, Oak Ridge, TN USA. [Kilczewski, Steve] Data Matrix Solut, Herndon, VA USA. [Wright, Jared] Bowhead Sci & Technol LLC, Belcamp, MD USA. RP Swab, JJ (reprint author), US Army Res Lab, Mat & Mfg Sci Div, Ceram & Transparent Mat Branch, Aberdeen, MD 21005 USA. EM jeffrey.j.swab.civ@mail.mil NR 32 TC 2 Z9 2 U1 2 U2 23 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0002-7820 EI 1551-2916 J9 J AM CERAM SOC JI J. Am. Ceram. Soc. PD FEB PY 2014 VL 97 IS 2 BP 592 EP 600 DI 10.1111/jace.12698 PG 9 WC Materials Science, Ceramics SC Materials Science GA 303OP UT WOS:000330684200039 ER PT J AU Liu, NT Holcomb, JB Wade, CE Batchinsky, AI Cancio, LC Darrah, MI Salinas, J AF Liu, Nehemiah T. Holcomb, John B. Wade, Charles E. Batchinsky, Andriy I. Cancio, Leopoldo C. Darrah, Mark I. Salinas, Jose TI Development and validation of a machine learning algorithm and hybrid system to predict the need for life-saving interventions in trauma patients SO MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING LA English DT Article DE Machine learning; Artificial intelligence; Clinical decision support systems; Life-saving interventions; Trauma ID ARTIFICIAL-INTELLIGENCE; VITAL SIGNS AB Accurate and effective diagnosis of actual injury severity can be problematic in trauma patients. Inherent physiologic compensatory mechanisms may prevent accurate diagnosis and mask true severity in many circumstances. The objective of this project was the development and validation of a multiparameter machine learning algorithm and system capable of predicting the need for life-saving interventions (LSIs) in trauma patients. Statistics based on means, slopes, and maxima of various vital sign measurements corresponding to 79 trauma patient records generated over 110,000 feature sets, which were used to develop, train, and implement the system. Comparisons among several machine learning models proved that a multilayer perceptron would best implement the algorithm in a hybrid system consisting of a machine learning component and basic detection rules. Additionally, 295,994 feature sets from 82 h of trauma patient data showed that the system can obtain 89.8 % accuracy within 5 min of recorded LSIs. Use of machine learning technologies combined with basic detection rules provides a potential approach for accurately assessing the need for LSIs in trauma patients. The performance of this system demonstrates that machine learning technology can be implemented in a real-time fashion and potentially used in a critical care environment. C1 [Liu, Nehemiah T.; Batchinsky, Andriy I.; Cancio, Leopoldo C.; Salinas, Jose] US Army Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Holcomb, John B.; Wade, Charles E.] Univ Texas Hlth Sci Ctr Houston, Dept Surg, Ctr Translat Injury Res, Houston, TX 77030 USA. [Darrah, Mark I.] Athena GTX Inc, Des Moines, IA 50321 USA. RP Liu, NT (reprint author), US Army Inst Surg Res, 3650 Chambers Pass,Bldg 3610, Ft Sam Houston, TX 78234 USA. EM nehemiah.liu@us.army.mil; john.holcomb@uth.tmc.edu; charles.e.wade@uth.tmc.edu; andriy.batchinsky1@us.army.mil; lee.cancio@us.army.mil; mdarrah@athenagtx.com; jose.salinas4@us.army.mil FU National Trauma Institute; US Army Combat Casualty Care Research Program; State of Texas Emergency Technology Fund FX This work was supported by the National Trauma Institute, the US Army Combat Casualty Care Research Program, and the State of Texas Emergency Technology Fund. We acknowledge the expertise, dedication, and professionalism of the Emergency Medical Services paramedics, nurses, and staff in Houston; Denise Hinds, Timothy Welch, and Jeannette Podbielski (the University of Texas Health Science Center in Houston, Texas, USA); and Kevin Stitcher (Athena GTX, Inc). We also thank Athena GTX, Inc. for the use of the Murphy factor to support algorithm development. NR 14 TC 10 Z9 11 U1 2 U2 8 PU SPRINGER HEIDELBERG PI HEIDELBERG PA TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY SN 0140-0118 EI 1741-0444 J9 MED BIOL ENG COMPUT JI Med. Biol. Eng. Comput. PD FEB PY 2014 VL 52 IS 2 BP 193 EP 203 DI 10.1007/s11517-013-1130-x PG 11 WC Computer Science, Interdisciplinary Applications; Engineering, Biomedical; Mathematical & Computational Biology; Medical Informatics SC Computer Science; Engineering; Mathematical & Computational Biology; Medical Informatics GA AA0SU UT WOS:000330808500010 PM 24263362 ER PT J AU Qiang, ZX Geng, JH Luo, T Zhang, J Jiang, SB AF Qiang, Zexuan Geng, Jihong Luo, Tao Zhang, Jun Jiang, Shibin TI High-efficiency ytterbium-free erbium-doped all-glass double cladding silicate glass fiber for resonantly-pumped fiber lasers SO APPLIED OPTICS LA English DT Article ID WAVE OUTPUT POWER; PHOSPHATE-GLASSES; AMPLIFIERS; ER AB A highly efficient ytterbium-free erbium-doped silicate glass fiber has been developed for high-power fiber laser applications at an eye-safe wavelength near 1.55 mu m. Our preliminary experiments show that high laser efficiency can be obtained from a relatively short length of the gain fiber when resonantly pumped at 1535 nm in both core-and cladding-pumping configurations. With a core-pumping configuration as high as 75%, optical-to-optical efficiency and 4 W output power were obtained at 1560 nm from a 1 m long gain fiber. When using a cladding-pumping configuration, approximately 13 W output power with 67.7% slope efficiency was demonstrated from a piece of 2 m long fiber. The lengths of silicate-based gain fiber are much shorter than their silica-based counterparts used in other experiments, which is significantly important for high-power narrow-band and/or pulsed laser applications. (C) 2014 Optical Society of America C1 [Qiang, Zexuan; Geng, Jihong; Luo, Tao; Jiang, Shibin] Advalue Photon Inc, Tucson, AZ 85714 USA. [Zhang, Jun] US Army Res Lab, Adelphi, MD 20783 USA. RP Jiang, SB (reprint author), Advalue Photon Inc, 3708 E Columbia St, Tucson, AZ 85714 USA. EM sjiang@advaluephotonics.com RI Chen, Ru/A-5105-2015 FU Department of Defense (DOD) SBIR phase II [W9113M-11-C-0040]; JTO project [13SA_0510] FX This work was supported by Department of Defense (DOD) SBIR phase II project (W9113M-11-C-0040), and JTO project (Contract No. #13S&A_0510). NR 16 TC 1 Z9 1 U1 2 U2 19 PU OPTICAL SOC AMER PI WASHINGTON PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA SN 1559-128X EI 2155-3165 J9 APPL OPTICS JI Appl. Optics PD FEB 1 PY 2014 VL 53 IS 4 BP 643 EP 647 DI 10.1364/AO.53.000643 PG 5 WC Optics SC Optics GA 300SS UT WOS:000330484500072 PM 24514181 ER PT J AU Munagala, S Sirasani, G Kokkonda, P Phadke, M Krynetskaia, N Lu, PH Sharom, FJ Chaudhury, S Abdulhameed, MDM Tawa, G Wallqvist, A Martinez, R Childers, W Abou-Gharbia, M Krynetskiy, E Andrade, RB AF Munagala, Surendrachary Sirasani, Gopal Kokkonda, Praveen Phadke, Manali Krynetskaia, Natalia Lu, Peihua Sharom, Frances J. Chaudhury, Sidhartha Abdulhameed, Mohamed Diwan M. Tawa, Gregory Wallqvist, Anders Martinez, Rogelio Childers, Wayne Abou-Gharbia, Magid Krynetskiy, Evgeny Andrade, Rodrigo B. TI Synthesis and evaluation of Strychnos alkaloids as MDR reversal agents for cancer cell eradication SO BIOORGANIC & MEDICINAL CHEMISTRY LA English DT Article DE Total synthesis; Strychnos alkaloids; P-glycoprotein; ABCB1; Multidrug resistance; Resensitization; Docking ID MEDIATED MULTIDRUG-RESISTANCE; ACCURATE DOCKING; NATURAL-PRODUCTS; VERAPAMIL; AMIDES; (-)-TUBIFOLIDINE; CYTOTOXICITY; TRANSPORTERS; REDUCTION; ONCOLOGY AB Natural products represent the fourth generation of multidrug resistance (MDR) reversal agents that resensitize MDR cancer cells overexpressing P-glycoprotein (Pgp) to cytotoxic agents. We have developed an effective synthetic route to prepare various Strychnos alkaloids and their derivatives. Molecular modeling of these alkaloids docked to a homology model of Pgp was employed to optimize ligand-protein interactions and design analogues with increased affinity to Pgp. Moreover, the compounds were evaluated for their (1) binding affinity to Pgp by fluorescence quenching, and (2) MDR reversal activity using a panel of in vitro and cell-based assays and compared to verapamil, a known inhibitor of Pgp activity. Compound 7 revealed the highest affinity to Pgp of all Strychnos congeners (K-d = 4.4 mu M), the strongest inhibition of Pgp ATPase activity, and the strongest MDR reversal effect in two Pgp-expressing cell lines. Altogether, our findings suggest the clinical potential of these synthesized compounds as viable Pgp modulators justifies further investigation. (C) 2013 Elsevier Ltd. All rights reserved. C1 [Munagala, Surendrachary; Sirasani, Gopal; Kokkonda, Praveen; Andrade, Rodrigo B.] Temple Univ, Dept Chem, Philadelphia, PA 19122 USA. [Phadke, Manali; Krynetskaia, Natalia; Martinez, Rogelio; Childers, Wayne; Abou-Gharbia, Magid; Krynetskiy, Evgeny] Temple Univ, Sch Pharm, Dept Pharmaceut Sci, Philadelphia, PA 19122 USA. [Lu, Peihua; Sharom, Frances J.] Univ Guelph, Dept Mol & Cellular Biol, Guelph, ON N1G 2W1, Canada. [Chaudhury, Sidhartha; Abdulhameed, Mohamed Diwan M.; Tawa, Gregory; Wallqvist, Anders] US Army Med Res & Mat Command, Telemed & Adv Technol Res Ctr, Dept Def Biotechnol, High Performance Comp Software Applicat Inst, Ft Detrick, MD 21702 USA. RP Andrade, RB (reprint author), Temple Univ, Dept Chem, Philadelphia, PA 19122 USA. EM randrade@temple.edu RI AbdulHameed, Mohamed Diwan M/O-3088-2015; Sharom, Frances/A-1613-2010; OI AbdulHameed, Mohamed Diwan M/0000-0003-1483-4084; Sharom, Frances/0000-0002-9521-5367; wallqvist, anders/0000-0002-9775-7469 FU National Science Foundation [CHE-1111558]; Drug Discovery Initiative (DDI) Grant from the Moulder Center for Drug Discovery, Temple University; Defense Threat Reduction Agency [TMTI0 004.09.BH.T] FX We are grateful to Dr. Yung-Chi Cheng (Yale University School of Medicine) for the generous gift of KB, KB-V20C, and KB-MDR cell lines. We thank Dr. Richard Pederson (Materia, Inc.) for catalyst support. Finally, this research was supported by the National Science Foundation (CHE-1111558) and the Drug Discovery Initiative (DDI) Grant from the Moulder Center for Drug Discovery, Temple University (RA, recipient). Additional funding was provided by the Defense Threat Reduction Agency through projects TMTI0 004.09.BH.T (AW, recipient). NR 37 TC 11 Z9 11 U1 2 U2 28 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0968-0896 EI 1464-3391 J9 BIOORGAN MED CHEM JI Bioorg. Med. Chem. PD FEB 1 PY 2014 VL 22 IS 3 BP 1148 EP 1155 DI 10.1016/j.bmc.2013.12.022 PG 8 WC Biochemistry & Molecular Biology; Chemistry, Medicinal; Chemistry, Organic SC Biochemistry & Molecular Biology; Pharmacology & Pharmacy; Chemistry GA 293NA UT WOS:000329977300023 PM 24405813 ER PT J AU Richards, KS Reddy, KR AF Richards, Kevin S. Reddy, Krishna R. TI Kinetic Energy Method for Predicting Initiation of Backward Erosion in Earthen Dams and Levees SO ENVIRONMENTAL & ENGINEERING GEOSCIENCE LA English DT Article DE Piping; Internal Erosion; Suffusion; Earthen Dams; Levees; Kinetic Energy ID SHEAR-STRESS; FLOW AB Current methods to evaluate the potential risk of earthen dam and levee failures by internal erosion fail to consider appropriate failure criteria for the initiation, continuation, and progression phases and are often based on subjective assessment. Six different internal erosion failure modes may occur within a dam or levee, its abutments, or the foundation that are triggered or facilitated by different mechanisms and therefore have different failure criteria. In non-cohesive soils, suffusion, backward erosion, heave, or concentrated leak erosion (scour) are possible, although the physical mechanisms driving the failure criterion for each of these are very different. Currently, no credible failure criteria exist for evaluation of the initiation of backward erosion. This article presents derivation of a specific failure criterion for initiation of backward erosion in non-cohesive soils using the critical kinetic energy (E-kcrit) of initiation. Laboratory experiments conducted with different soils showed that E-kcrit is affected by the physical characteristics of the soil, effective stress conditions, and angle of the seepage path. In internally stable, non-cohesive soils (e.g., uniform medium sands) with up to 6 percent non-plastic fines, backward erosion initiated when the E-kcrit of seepage exceeded 0.075 Joules. In non-cohesive soils with 10 percent non-plastic fines, which are also prone to suffusion, the E-kcrit for backward erosion is reduced by a factor of as much as 100. Moreover, in soil with 20 percent plastic fines, initiation of backward erosion did not occur. Concentrated leak erosion along hydraulic-induced fractures was the dominant process of internal erosion in soils with plastic fines. A new backward erosion assessment methodology based on the factor of safety is proposed for initiation of backward erosion that relates the laboratory-derived E-kcrit and the anticipated maximum actual kinetic energy, as measured in the field or estimated during design. The advantage of this method is that laboratory-derived E-kcrit can take into account the natural factors that affect initiation of backward erosion. Several examples are presented to demonstrate the application of the factor of safety methodology under typical field conditions. C1 [Richards, Kevin S.] US Army Corps Engineers, Inst Water Resources, Risk Management Ctr, Pittsburgh, PA 15222 USA. [Reddy, Krishna R.] Univ Illinois, Dept Civil & Mat Engn, Chicago, IL 60607 USA. RP Richards, KS (reprint author), US Army Corps Engineers, Inst Water Resources, Risk Management Ctr, Pittsburgh, PA 15222 USA. EM kevin.s.richards@usace.army.mil RI Reddy, Krishna/B-7263-2009 OI Reddy, Krishna/0000-0002-6577-1151 NR 34 TC 2 Z9 2 U1 1 U2 16 PU GEOLOGICAL SOC AMER, INC PI BOULDER PA PO BOX 9140, BOULDER, CO 80301-9140 USA SN 1078-7275 EI 1558-9161 J9 ENVIRON ENG GEOSCI JI Environ. Eng. Geosci. PD FEB PY 2014 VL 20 IS 1 BP 85 EP 97 PG 13 WC Engineering, Environmental; Engineering, Geological; Geosciences, Multidisciplinary SC Engineering; Geology GA 301CQ UT WOS:000330510700005 ER PT J AU Lundberg, CA Banks, TA Mikita, C Mikita, J AF Lundberg, Cory A. Banks, Taylor A. Mikita, Cecilia Mikita, Jeffrey TI Selective IgM Deficiency Presenting As Cryptogenic Organizing Pneumonia SO JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY LA English DT Meeting Abstract CT Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology (AAAAI) CY FEB 28-MAR 04, 2014 CL San Diego, CA SP Amer Acad Allergy Asthma & Immunol C1 [Lundberg, Cory A.; Banks, Taylor A.; Mikita, Jeffrey] Walter Reed Natl Mil Med Ctr, Bethesda, MD USA. [Mikita, Cecilia] Walter Reed Army Med Ctr, Bethesda, MD USA. NR 0 TC 0 Z9 0 U1 0 U2 4 PU MOSBY-ELSEVIER PI NEW YORK PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA SN 0091-6749 EI 1097-6825 J9 J ALLERGY CLIN IMMUN JI J. Allergy Clin. Immunol. PD FEB PY 2014 VL 133 IS 2 SU S MA 39 BP AB11 EP AB11 PG 1 WC Allergy; Immunology SC Allergy; Immunology GA 297FO UT WOS:000330241300040 ER PT J AU Cao, JJ Pasiakos, SM Margolis, LM Sauter, ER Whigham, LD McClung, JP Young, AJ Combs, GF AF Cao, Jay J. Pasiakos, Stefan M. Margolis, Lee M. Sauter, Edward R. Whigham, Leah D. McClung, James P. Young, Andrew J. Combs, Gerald F., Jr. TI Calcium homeostasis and bone metabolic responses to high-protein diets during energy deficit in healthy young adults: a randomized controlled trial SO AMERICAN JOURNAL OF CLINICAL NUTRITION LA English DT Article ID INDUCED WEIGHT-LOSS; OVERWEIGHT PREMENOPAUSAL WOMEN; NET ACID EXCRETION; FAT-FREE MASS; POSTMENOPAUSAL WOMEN; CALORIC RESTRICTION; MINERAL DENSITY; VITAMIN-D; INDUCED HYPERCALCIURIA; POTASSIUM BICARBONATE AB Background: Although consuming dietary protein above current recommendations during energy deficit (ED) preserves lean body mass, concerns have been raised regarding the effects of high-protein diets on bone health. Objective: The objective was to determine whether calcium homeostasis and bone turnover are affected by high-protein diets during weight maintenance (WM) and ED. Design: In a randomized, parallel-design, controlled trial of 32 men and 7 Women, volunteers were assigned diets providing protein at 0.8 [Recommended Dietary Allowance (RDA)], 1.6 (2 x RDA), or 2.4 (3 x RDA) g . kg(-1) . d(-1) for 31 d. Ten days of WM preceded 21 d of ED during which total daily ED was 40%, achieved by reduced dietary energy intake (similar to 30%) and increased physical activity (similar to 10%). The macronutrient composition (protein g . kg(-1) . d(-1) and % fat) was held constant from WM to ED. Calcium absorption (ratio of Ca-44 to Ca-42) and circulating indexes of bone turnover were determined at day 8 (WM) and day 29 (ED). Results: Regardless of energy state, mean (+/- SEM) urinary pH was lower (P < 0.05) at 2 x RDA (6.28 +/- 0.05) and 3 x RDA (6.23 +/- 0.06) than at the RDA (6.54 +/- 0.06). However, protein had no effect on either, urinary calcium excretion (P > 0.05) or the amount of calcium retained (P > 0.05). ED decreased serum insulin-like growth factor I concentrations and increased serum tartrate-resistant acid phosphatase and 25-hydroxyvitamin D concentrations (P < 0.01). Remaining markers of bone turnover and whole-body bone mineral density and content were not affected by either the protein level or ED (P > 0.05). Conclusion: These data demonstrate that short-term consumption of high-protein diets does not disrupt calcium homeostasis and is not detrimental to skeletal integrity. C1 [Cao, Jay J.; Whigham, Leah D.; Combs, Gerald F., Jr.] ARS, USDA, Grand Forks Human Nutr Res Ctr, Grand Forks, ND 58202 USA. [Pasiakos, Stefan M.; Margolis, Lee M.; McClung, James P.; Young, Andrew J.] US Army, Environm Med Res Inst, Mil Nutr Div, Natick, MA 01760 USA. [Sauter, Edward R.] Univ N Dakota, Sch Med & Hlth Sci, Grand Forks, ND 58201 USA. RP Cao, JJ (reprint author), ARS, USDA, Grand Forks Human Nutr Res Ctr, 2420 2nd Ave N, Grand Forks, ND 58202 USA. EM jay.cao@ars.usda.gov RI McClung, James/A-1989-2009; Pasiakos, Stefan/E-6295-2014; Biguzzi, Felipe/E-4724-2015 OI Pasiakos, Stefan/0000-0002-5378-5820; FU US Army Medical Research and Material Command; USDA Agricultural Research Service program "Bone Metabolism in Obesity" Current Research Information System [5450-51000-046-00D] FX Supported by the US Army Medical Research and Material Command and the USDA Agricultural Research Service program "Bone Metabolism in Obesity" Current Research Information System (no. 5450-51000-046-00D) as part of the authors' official duties. NR 62 TC 9 Z9 9 U1 0 U2 14 PU AMER SOC NUTRITION-ASN PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 USA SN 0002-9165 EI 1938-3207 J9 AM J CLIN NUTR JI Am. J. Clin. Nutr. PD FEB PY 2014 VL 99 IS 2 BP 400 EP 407 DI 10.3945/ajcn.113.073809 PG 8 WC Nutrition & Dietetics SC Nutrition & Dietetics GA 295XR UT WOS:000330150200021 PM 24284444 ER PT J AU Rodriguez-Barraquer, I Buathong, R Iamsirithaworn, S Nisalak, A Lessler, J Jarman, RG Gibbons, RV Cummings, DAT AF Rodriguez-Barraquer, Isabel Buathong, Rome Iamsirithaworn, Sopon Nisalak, Ananda Lessler, Justin Jarman, Richard G. Gibbons, Robert V. Cummings, Derek A. T. TI Revisiting Rayong: Shifting Seroprofiles of Dengue in Thailand and Their Implications for Transmission and Control SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Article DE basic reproductive number; critical vaccination fraction; demography; dengue; force of infection; transmission dynamics ID RISK-FACTORS; INFECTIOUS-DISEASE; HEMORRHAGIC-FEVER; SOUTHERN VIETNAM; AGE; BRAZIL; FORCE AB Dengue virus has traditionally caused substantial morbidity and mortality among children less than 15 years of age in Southeast Asia. Over the last 2 decades, a significant increase in the mean age of cases has been reported, and a once pediatric disease now causes substantial burden among the adult population. An age-stratified serological study (n 1,736) was conducted in 2010 among schoolchildren in the Mueang Rayong district of Thailand, where a similar study had been conducted in 1980/1981. Serotype-specific forces of infection ((t)) and basic reproductive numbers (R-0) of dengue were estimated for the periods 19691980 and 19932010. Despite a significant increase in the age at exposure and a decrease in (t) from 0.038/year to 0.019/year, R-0 changed only from 3.3 to 3.2. Significant heterogeneity was observed across subdistricts and schools, with R-0 ranging between 1.7 and 6.8. These findings are consistent with the idea that the observed age shift might be a consequence of the demographic transition in Thailand. Changes in critical vaccination fractions, estimated by using R-0, have not accompanied the increase in age at exposure. These results have implications for dengue control interventions because multiple countries in Southeast Asia are undergoing similar demographic transitions. It is likely that dengue will never again be a disease exclusively of children. C1 [Rodriguez-Barraquer, Isabel; Lessler, Justin; Cummings, Derek A. T.] Johns Hopkins Univ, Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA. [Buathong, Rome; Iamsirithaworn, Sopon] Minist Publ Hlth, Bur Epidemiol, Nonthaburi, Thailand. [Nisalak, Ananda; Jarman, Richard G.; Gibbons, Robert V.] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand. [Jarman, Richard G.] Walter Reed Army Inst Res, Viral Dis Branch, Silver Spring, MD USA. RP Cummings, DAT (reprint author), Johns Hopkins Bloomberg Sch Publ Hlth, 615 North Wolfe St, Baltimore, MD 21205 USA. EM dcumming@jhsph.edu OI Lessler, Justin/0000-0002-9741-8109 FU National Institute of General Medical Sciences Models of Infectious Disease Agent Study [1U54GM088491-0109]; Bill and Melinda Gates Foundation Vaccine Modeling Initiative FX Financial support was provided by the National Institute of General Medical Sciences Models of Infectious Disease Agent Study (grant 1U54GM088491-0109 to D.A.T.C. and I.R.B.) and the Bill and Melinda Gates Foundation Vaccine Modeling Initiative (which supported D.A.T.C.). D.A.T.C. holds a Career Award at the Scientific Interface from the Burroughs Wellcome Fund. NR 35 TC 18 Z9 18 U1 1 U2 10 PU OXFORD UNIV PRESS INC PI CARY PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA SN 0002-9262 EI 1476-6256 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD FEB 1 PY 2014 VL 179 IS 3 BP 353 EP 360 DI 10.1093/aje/kwt256 PG 8 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA 296NA UT WOS:000330190600010 PM 24197388 ER PT J AU Reiter, M Schwope, R AF Reiter, Michael Schwope, Ryan TI Finding a niche Magnetic resonance imaging located an often-overlooked source of uterine bleeding SO AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY LA English DT Editorial Material C1 [Reiter, Michael; Schwope, Ryan] Brooke Army Med Ctr, Dept Radiol, San Antonio, TX 78234 USA. RP Reiter, M (reprint author), Brooke Army Med Ctr, 3851 Roger Brooke Dr, San Antonio, TX 78234 USA. EM michael.reiter1@us.army.mil NR 4 TC 0 Z9 0 U1 0 U2 0 PU MOSBY-ELSEVIER PI NEW YORK PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA SN 0002-9378 EI 1097-6868 J9 AM J OBSTET GYNECOL JI Am. J. Obstet. Gynecol. PD FEB PY 2014 VL 210 IS 2 AR 171.e1 DI 10.1016/j.ajog.2013.06.002 PG 2 WC Obstetrics & Gynecology SC Obstetrics & Gynecology GA 295OT UT WOS:000330126100030 PM 23747492 ER PT J AU Zainuddin, S Arefin, T Fahim, A Hosur, MV Tyson, JD Kumar, A Trovillion, J Jeelani, S AF Zainuddin, S. Arefin, T. Fahim, A. Hosur, M. V. Tyson, J. D. Kumar, Ashok Trovillion, J. Jeelani, S. TI Recovery and improvement in low-velocity impact properties of e-glass/epoxy composites through novel self-healing technique SO COMPOSITE STRUCTURES LA English DT Article DE Self-healing agent; Hollow glass fibers; E-glass/epoxy; Low-velocity impact ID FIBER-REINFORCED POLYMER; HOLLOW GLASS-FIBERS; REPAIR; DAMAGE; STRENGTH; CRACKS AB We report the recovery and improvement in low-velocity impact properties of e-glass/epoxy composites achieved through embedding self-healing agent (SHA) filled hollow glass fibers (HGFs). At first, catalytic technique was used to fill bonded HGFs with SHA. The HGFs were then laid on e-glass fibers and the laminates were fabricated using vacuum assisted resin infusion molding (VARIM) process. Low-velocity impact tests at two different energy levels were conducted multiple times in the closest proximity to determine the healing efficiency. Results showed significant improvement and recovery in impact properties with 53.6% gain in peak load after second impact in SHA filled HGFs samples in comparison to control samples. A significant gain in energy to peak load was also found in SHA filled samples with 86.6% improvement over control samples. Optical microscopy images of SHA filled HGFs samples showed filling of cracks developed after impact. A distinct damage behavior was observed in control and HGFs embedded samples. (C) 2013 Elsevier Ltd. All rights reserved. C1 [Zainuddin, S.; Fahim, A.; Hosur, M. V.; Jeelani, S.] Tuskegee Univ, Dept Mat Sci & Engn, Tuskegee, AL 36088 USA. [Arefin, T.; Tyson, J. D.; Jeelani, S.] Tuskegee Univ, Dept Mech Engn, Tuskegee, AL 36088 USA. [Kumar, Ashok; Trovillion, J.] US Army Engineer Res & Dev Ctr, Construct Engn Res Lab, Champaign, IL 61821 USA. RP Zainuddin, S (reprint author), Tuskegee Univ, Dept Mat Sci & Engn, Tuskegee, AL 36088 USA. EM szainuddin@mytu.tuskegee.edu OI Kumar, Ashok/0000-0003-4694-4819 FU U.S. Engineer Research Development Corporation - Construction Engineering Research Laboratory (ERDC-CERL); NSF-Alabama EPSCoR FX The authors would like to acknowledge U.S. Engineer Research Development Corporation - Construction Engineering Research Laboratory (ERDC-CERL) and NSF-Alabama EPSCoR for funding this work. NR 28 TC 16 Z9 16 U1 5 U2 52 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0263-8223 EI 1879-1085 J9 COMPOS STRUCT JI Compos. Struct. PD FEB PY 2014 VL 108 BP 277 EP 286 DI 10.1016/j.compstruct.2013.09.023 PG 10 WC Materials Science, Composites SC Materials Science GA 292DD UT WOS:000329881500027 ER PT J AU Liu, KC Ghoshal, A AF Liu, Kuang C. Ghoshal, Anindya TI Inherent symmetry and microstructure ambiguity in micromechanics SO COMPOSITE STRUCTURES LA English DT Article DE Micromechanics; Microstructure; Effective properties; Homogenization; Localization ID GENERALIZED-METHOD; COMPOSITES; CELLS; MODEL AB The computational cost of micromechanics for heterogeneous materials can be reduced in certain cases where symmetric boundary conditions are applicable. We derived an eighth symmetric formulation of the Generalized Method of Cells for triply periodic microstructures. During this endeavor, an inherent symmetry was discovered. This implied that all repeating unit cells may be quarter symmetric representations of other microstructures. Additionally, it was discovered that a repeating unit cell can have columns of subcells swapped with no changes to the local or global fields. We concluded that first-order micromechanics are not well suited for capturing detailed or complex microstructures; however, higher-order theories, such as High Fidelity Generalized Method of Cells, can adequately model these microstructures. (C) 2013 Elsevier Ltd. All rights reserved. C1 [Liu, Kuang C.; Ghoshal, Anindya] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Liu, KC (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. EM kuang.c.liu@gmail.com FU U.S. Army Research Laboratory FX This research was supported in part by an appointment to the Postgraduate Research Participation Program at the U.S. Army Research Laboratory administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the U.S. Department of Energy and USARL. NR 11 TC 1 Z9 1 U1 0 U2 6 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0263-8223 EI 1879-1085 J9 COMPOS STRUCT JI Compos. Struct. PD FEB PY 2014 VL 108 BP 311 EP 318 DI 10.1016/j.compstruct.2013.07.054 PG 8 WC Materials Science, Composites SC Materials Science GA 292DD UT WOS:000329881500031 ER PT J AU Cardile, AP Briggs, H Burguete, SR Herrera, M Wickes, BL Jorgensen, JH AF Cardile, Anthony P. Briggs, Heather Burguete, S. Rodrigo Herrera, Monica Wickes, Brian L. Jorgensen, James H. TI Treatment of KPC-2 Enterobacter cloacae empyema with cefepime and levofloxacin SO DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE LA English DT Article DE Enterobacter cloacae; KPC; Carbapenemase; Empyema ID KLEBSIELLA-PNEUMONIAE CARBAPENEMASE; K.-PNEUMONIAE; COLISTIN-RESISTANT; COMBINATION; INFECTIONS; ANTIBIOTICS; REGIMENS; RIFAMPIN; THERAPY AB Carbapenem-resistant Enterobacteriaceae infections are becoming more common, are associated with high mortality rates, and are difficult to treat due to multiple mechanisms of resistance. We describe the successful treatment of Klebsiella pneumoniae carbapenemase-expressing Enterobacter cloacae empyema in a lung transplant recipient with cefepime and levofloxacin. Published by Elsevier Inc. C1 [Cardile, Anthony P.] Brooke Army Med Ctr, Infect Dis Serv, Houston, TX USA. [Briggs, Heather; Burguete, S. Rodrigo; Jorgensen, James H.] Univ Texas Hlth Sci Ctr San Antonio, Dept Med, San Antonio, TX 78229 USA. [Herrera, Monica; Wickes, Brian L.; Jorgensen, James H.] Univ Texas Hlth Sci Ctr San Antonio, Dept Microbiol, San Antonio, TX 78229 USA. [Jorgensen, James H.] Univ Texas Hlth Sci Ctr San Antonio, Dept Pathol, San Antonio, TX 78229 USA. RP Cardile, AP (reprint author), Brooke Army Med Ctr, Infect Dis Serv, Houston, TX USA. EM anthony.p.cardile.mil@mail.mil FU bioMerieux; Merck FX Disclosure statement: JHJ has served on advisory boards for Accelerate Diagnostics and Merck and has received research support from bioMerieux and Merck. All other authors have no disclosures. NR 19 TC 4 Z9 4 U1 0 U2 4 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 0732-8893 EI 1879-0070 J9 DIAGN MICR INFEC DIS JI Diagn. Microbiol. Infect. Dis. PD FEB PY 2014 VL 78 IS 2 BP 199 EP 200 DI 10.1016/j.diagmicrobio.2013.10.012 PG 2 WC Infectious Diseases; Microbiology SC Infectious Diseases; Microbiology GA 295XM UT WOS:000330149700019 PM 24268534 ER PT J AU Chen, JYC Barnes, MJ AF Chen, Jessie Y. C. Barnes, Michael J. TI Human-Agent Teaming for Multirobot Control: A Review of Human Factors Issues SO IEEE TRANSACTIONS ON HUMAN-MACHINE SYSTEMS LA English DT Review DE Automation; human-agent (H-A) teaming; human factors; human-robot interaction; individual differences; intelligent agent; situation awareness; trust; user interface design ID HUMAN-ROBOT INTERACTION; SIMULATED MULTITASKING ENVIRONMENT; HUMAN-AUTOMATION INTERACTIONS; HUMAN-PERFORMANCE ISSUES; WORKING-MEMORY CAPACITY; USER-INTERFACE DESIGN; VIDEO GAME PLAYERS; INDIVIDUAL-DIFFERENCES; DECISION-SUPPORT; CONCURRENT PERFORMANCE AB The human factors literature on intelligent systems was reviewed in relation to the following: efficient human supervision of multiple robots, appropriate human trust in the automated systems, maintenance of human operator's situation awareness, individual differences in human-agent (H-A) interaction, and retention of human decision authority. A number of approaches-from flexible automation to autonomous agents-were reviewed, and their advantages and disadvantages were discussed. In addition, two key human performance issues (trust and situation awareness) related to H-A teaming for multirobot control and some promising user interface design solutions to address these issues were discussed. Some major individual differences factors (operator spatial ability, attentional control ability, and gaming experience) were identified that may impact H-A teaming in the context of robotics control. C1 [Chen, Jessie Y. C.] US Army, Res Lab, Human Res & Engn Directorate, Orlando, FL 32826 USA. [Barnes, Michael J.] US Army, Res Laboratory, Human Res & Engn Directorate, Ft Huachuca, AZ 85613 USA. RP Chen, JYC (reprint author), US Army, Res Lab, Human Res & Engn Directorate, Orlando, FL 32826 USA. EM jessie.chen@us.army.mil; michael.j.barnes.civ@mail.mil FU U.S. Department of Army under the Army Technology Objective of Safe Operations for Unmanned Reconnaissance in Complex Environments FX This work was supported by the U.S. Department of Army under the Army Technology Objective of Safe Operations for Unmanned Reconnaissance in Complex Environments. This paper was recommended by Associate Editor A. M. Howard. NR 198 TC 25 Z9 25 U1 15 U2 53 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 2168-2291 EI 2168-2305 J9 IEEE T HUM-MACH SYST JI IEEE T. Hum.-Mach. Syst. PD FEB PY 2014 VL 44 IS 1 BP 13 EP 29 DI 10.1109/THMS.2013.2293535 PG 17 WC Computer Science, Artificial Intelligence; Computer Science, Cybernetics SC Computer Science GA 296ET UT WOS:000330168600002 ER PT J AU Regli, WC Mayk, I Cannon, CT Kopena, JB Lass, RN Mongan, WM Nguyen, DN Salvage, JK Sultanik, EA Usbeck, K AF Regli, William C. Mayk, Israel Cannon, Christopher T. Kopena, Joseph B. Lass, Robert N. Mongan, William M. Nguyen, Duc N. Salvage, Jeff K. Sultanik, Evan A. Usbeck, Kyle TI Development and Specification of a Reference Architecture for Agent-Based Systems SO IEEE TRANSACTIONS ON SYSTEMS MAN CYBERNETICS-SYSTEMS LA English DT Article DE Agents; distributed artificial intelligence (AI); multiagent; reference model; reverse engineering; software engineering; software architecture ID COMPLEX; MODEL AB The recent growth of agent-based software systems was achieved without the development of a reference architecture. From a software engineering standpoint, a reference architecture is necessary to compare, evaluate, and integrate past, current, and future agent-based software systems. The agent systems reference architecture (ASRA) advances the agent-based system development process by providing a set of key interaction patterns for functional areas that exist between the layers and protocols of agent-based systems. Furthermore, the ASRA identifies the points for interoperability between agent-based systems and increases the level of discussion when referring to agent-based systems. This paper presents methodology, grounded in software forensics, to develop the ASRA and provides an overview of the resulting architectural representation. The methodology uses an approach based on software engineering techniques adapted to study agent frameworks-the libraries and tools for building agent systems. The resulting ASRA can serve as an abstract representation of the components necessary for facilitating comparison, integration, and interoperation of software systems composed of agents. C1 [Regli, William C.; Cannon, Christopher T.; Kopena, Joseph B.; Lass, Robert N.; Mongan, William M.; Nguyen, Duc N.; Salvage, Jeff K.; Sultanik, Evan A.] Drexel Univ, Philadelphia, PA 19104 USA. [Mayk, Israel] US Army Res Dev & Engn Command, Commun Elect Res Dev & Engn Ctr, Aberdeen Proving Ground, MD 21001 USA. [Usbeck, Kyle] Raytheon BBN Technol, Cambridge, MA 02138 USA. RP Regli, WC (reprint author), Drexel Univ, Philadelphia, PA 19104 USA. EM regli@drexel.edu; israel.mayk@us.army.mil; ctc82@drexel.edu; jbk23@drexel.edu; rnl22@drexel.edu; wmm24@drexel.edu; kusbeck@bbn.com NR 48 TC 0 Z9 0 U1 2 U2 11 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 2168-2216 J9 IEEE T SYST MAN CY-S JI IEEE Trans. Syst. Man Cybern. -Syst. PD FEB PY 2014 VL 44 IS 2 BP 146 EP 161 DI 10.1109/TSMCC.2013.2263132 PG 16 WC Automation & Control Systems; Computer Science, Cybernetics SC Automation & Control Systems; Computer Science GA 295QY UT WOS:000330131800002 ER PT J AU Anderson, KB Gibbons, RV Cummings, DAT Nisalak, A Green, S Libraty, DH Jarman, RG Srikiatkhachorn, A Mammen, MP Darunee, B Yoon, IK Endy, TP AF Anderson, Kathryn B. Gibbons, Robert V. Cummings, Derek A. T. Nisalak, Ananda Green, Sharone Libraty, Daniel H. Jarman, Richard G. Srikiatkhachorn, Anon Mammen, Mammen P. Darunee, Buddhari Yoon, In-Kyu Endy, Timothy P. TI A Shorter Time Interval Between First and Second Dengue Infections Is Associated With Protection From Clinical Illness in a School-based Cohort in Thailand SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article DE dengue; epidemiology; antibodies; immunity; pathogenesis; prospective cohort study ID HEMORRHAGIC-FEVER; VIRUS-INFECTION; KAMPHAENG PHET; SHOCK SYNDROME; DV INFECTION; RISK-FACTORS; ANTIBODY; DISEASE; CUBA; TRANSMISSION AB Background. Despite the strong association between secondary dengue virus (DENV) infections and dengue hemorrhagic fever (DHF), the majority of secondary infections are subclinical or mild. The determinants of clinical severity remain unclear, though studies indicate a titer-dependent and time-dependent role of cross-protective anti-DENV antibodies. Methods. Data from 2 sequential prospective cohort studies were analyzed for subclinical and symptomatic DENV infections in schoolchildren in Kamphaeng Phet, Thailand (1998-2002 and 2004-2007). Children experiencing >= 1 DENV infection were selected as the population for analysis (contributing 2169 person-years of follow-up). Results. In total, 1696 children had >= 1 DENV infection detected during their enrollment; 268 experienced 2 or more infections. A shorter time interval between infections was associated with subclinical infection in children seronegative for DENV at enrollment, for whom a second-detected DENV infection is more likely to reflect a true second infection (average of 2.6 years between infections for DHF, 1.9 for DF, and 1.6 for subclinical infections). Conclusions. These findings support a pathogenesis model where cross-reactive antibodies wane from higher-titer, protective levels to lower-titer, detrimental levels. This is one of the first studies of human subjects to suggest a window of cross-protection following DENV infection since Sabin's challenge studies in the 1940s. C1 [Anderson, Kathryn B.] Univ Minnesota, Sch Med, Dept Med, Minneapolis, MN 55455 USA. [Gibbons, Robert V.; Nisalak, Ananda; Mammen, Mammen P.; Darunee, Buddhari; Yoon, In-Kyu] Armed Forces Res Inst Med Sci, Dept Virol, Bangkok 10400, Thailand. [Cummings, Derek A. T.] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA. [Green, Sharone; Libraty, Daniel H.; Srikiatkhachorn, Anon] Univ Massachusetts, Sch Med, Ctr Infect Dis & Vaccine Res, Worcester, MA USA. [Jarman, Richard G.] Walter Reed Army Inst Res, Div Viral Dis, Silver Springs, NY USA. [Endy, Timothy P.] SUNY Upstate Med Univ, Syracuse, NY 13210 USA. RP Anderson, KB (reprint author), Univ Minnesota, Sch Med, Dept Med, 420 Delaware St SE,MMC 194, Minneapolis, MN 55455 USA. EM ande7622@umn.edu FU United States Army Medical Research and Materiel Command, Ft Detrick, MD, USA; CDC [1R36CK00104]; NIH [P01 AI034533]; Military Infectious Diseases Research Program (MIDRP) FX The clinical trial was supported by the United States Army Medical Research and Materiel Command, Ft Detrick, MD, USA. The analysis was supported by Dissertation grant 1R36CK00104 from the CDC, NIH Grant P01 AI034533, and the Military Infectious Diseases Research Program (MIDRP). The opinions expressed in this manuscript do not necessarily represent the official views of the US Department of Defense, or the US Department of the Army. NR 30 TC 37 Z9 37 U1 1 U2 7 PU OXFORD UNIV PRESS INC PI CARY PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA SN 0022-1899 EI 1537-6613 J9 J INFECT DIS JI J. Infect. Dis. PD FEB 1 PY 2014 VL 209 IS 3 BP 360 EP 368 DI 10.1093/infdis/jit436 PG 9 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA 292SE UT WOS:000329921700010 PM 23964110 ER PT J AU Peacock, ZS Aghaloo, T Bouloux, GF Cillo, JE Hale, RG Le, AD Lee, JS Kademani, D AF Peacock, Zachary S. Aghaloo, Tara Bouloux, Gary F. Cillo, Joseph E., Jr. Hale, Robert G. Le, Anh D. Lee, Janice S. Kademani, Deepak TI Proceedings From the 2013 American Association of Oral and Maxillofacial Surgeons Research Summit SO JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY LA English DT Article ID BISPHOSPHONATE-RELATED OSTEONECROSIS; TRANSORAL ROBOTIC SURGERY; ADVANCED OROPHARYNX CANCER; SQUAMOUS-CELL CARCINOMA; JAW-LIKE DISEASE; RISK-FACTORS; MULTIPLE-MYELOMA; HUMAN-PAPILLOMAVIRUS; SURGICAL-MANAGEMENT; PARATHYROID-HORMONE AB The American Association of Oral and Maxillofacial Surgeons, the Oral and Maxillofacial Surgery Foundation, and the International Association of Oral and Maxillofacial Surgeons sponsored the fifth research summit, which convened on May 2 and 3 in Rosemont, Illinois. The Research Summits are convened biennially to facilitate the discussion and collaboration of oral and maxillofacial surgeons with clinical and basic science researchers in fields affecting the specialty. The goal is to advance the field of oral and maxillofacial surgery through exposure and education in topics that ultimately benefit the oral and maxillofacial surgical patient. This edition of the research summit included the topics of robotic surgery and antiresorptive-related osteonecrosis of the jaws (ARONJ). Most importantly, this research summit saw the development of research interest groups (RIGs) in the fields of anesthesia, maxillofacial oncology and reconstructive surgery, obstructive sleep apnea and orthognathic surgery, temporomandibular joint surgery, and trauma. These RIGs developed specific research goals with a plan to continue working on potential projects at the AAOMS Clinical Trials Course on May 7 to 9, 2013 at the University of Michigan in Ann Arbor. The summit program was developed by the AAOMS Committee on Research Planning and Technology Assessment. The charge of the committee is to encourage and promote research within the specialty and to encourage interdisciplinary collaboration. The research summit serves as a platform for oral and maxillofacial surgeons to lead the goal of advancement of research relevant to the specialty. This article provides an overview of the presentations that were made in the sessions on robotic surgery and ARONJ. The research summit keynote address and two additional presentations on patient registries are summarized and updates from the RIGs that were formed at the 2013 research summit are highlighted. (C) 2014 American Association of Oral and Maxillofacial Surgeons C1 [Peacock, Zachary S.] Massachusetts Gen Hosp, Dept Oral & Maxillofacial Surg, Boston, MA 02114 USA. [Peacock, Zachary S.] Harvard Univ, Sch Dent Med, Boston, MA 02115 USA. [Aghaloo, Tara] Univ Calif Los Angeles, Div Oral & Maxillofacial Surg, Los Angeles, CA USA. [Bouloux, Gary F.] Emory Univ, Sch Med, Dept Surg, Div Oral & Maxillofacial Surg, Atlanta, GA 30322 USA. [Cillo, Joseph E., Jr.] Allegheny Gen Hosp, Div Oral & Maxillofacial Surg, Pittsburgh, PA 15212 USA. [Hale, Robert G.] US Army, Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Le, Anh D.] Univ Penn, Dept Oral & Maxillofacial Surg Pharmacol, Philadelphia, PA 19104 USA. [Lee, Janice S.] Natl Inst Dent & Craniofacial Res, NIH, Bethesda, MD USA. [Kademani, Deepak] Univ Minnesota, Div Oral & Maxillofacial Surg, Minneapolis, MN USA. RP Peacock, ZS (reprint author), Massachusetts Gen Hosp, Dept Oral & Maxillofacial Surg, 55 Fruit St,Warren 1201, Boston, MA 02114 USA. EM zpeacock@partners.org NR 95 TC 1 Z9 1 U1 0 U2 5 PU W B SAUNDERS CO-ELSEVIER INC PI PHILADELPHIA PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA SN 0278-2391 EI 1531-5053 J9 J ORAL MAXIL SURG JI J. Oral Maxillofac. Surg. PD FEB PY 2014 VL 72 IS 2 BP 241 EP 253 DI 10.1016/j.joms.2013.09.037 PG 13 WC Dentistry, Oral Surgery & Medicine SC Dentistry, Oral Surgery & Medicine GA 290KV UT WOS:000329756500005 PM 24438595 ER PT J AU Yuen, W Johnsen, DL Koloutsou-Vakakis, S Rood, MJ Kim, BJ Kemme, MR AF Yuen, Wangki Johnsen, David L. Koloutsou-Vakakis, Sotiria Rood, Mark J. Kim, Byung J. Kemme, Michael R. TI Open burning and open detonation PM10 mass emission factor measurements with optical remote sensing SO JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION LA English DT Article ID STATIONARY SHORT-TERM; PARTICULATE; DUST AB Emission factors (EFs) of particulate matter with aerodynamic diameter 10 mu m (PM10) from the open burning/open detonation (OB/OD) of energetic materials were measured using a hybrid-optical remote sensing (hybrid-ORS) method. This method is based on the measurement of range-resolved PM backscattering values with a micropulse light detection and ranging (LIDAR; MPL) device. Field measurements were completed during March 2010 at Tooele Army Depot, Utah, which is an arid continental site. PM10 EFs were quantified for OB of M1 propellant and OD of 2,4,6-trinitrotoluene (TNT). EFs from this study are compared with previous OB/OD measurements reported in the literature that have been determined with point measurements either in enclosed or ambient environments, and with concurrent airborne point measurements. PM10 mass EFs, determined with the hybrid-ORS method, were 7.8x10(-3) kg PM10/kg M1 from OB of M1 propellant, and 0.20 kg PM10/kg TNT from OD of TNT. Compared with previous results reported in the literature, the hybrid-ORS method EFs were 13% larger for OB and 174% larger for OD. Compared with the concurrent airborne measurements, EF values from the hybrid-ORS method were 37% larger for OB and 54% larger for OD. For TNT, no statistically significant differences were observed for the EFs measured during the detonation of 22.7 and 45.4 kg of TNT, supporting that the total amount of detonated mass in this mass range does not have an effect on the EFs for OD of TNT. Implications: Particulate matter (PM) in the atmosphere affects the health of humans and ecosystems, visibility, and climate. Fugitive PM emissions are not well characterized because of spatial and temporal ubiquity and heterogeneity. The hybrid-ORS method is appropriate for quantifying fugitive PM emission factors (EFs) because it captures the spatial and temporal dispersion of ground level and elevated plumes in real time, without requiring numerous point measurement devices. The method can be applied to provide an opportunity to reduce the uncertainty of fugitive PM EFs and readily update PM emissions in National Emission Inventories for a range of fugitive PM sources. C1 [Yuen, Wangki; Johnsen, David L.; Koloutsou-Vakakis, Sotiria; Rood, Mark J.] Univ Illinois, Dept Civil & Environm Engn, Urbana, IL 61801 USA. [Kim, Byung J.; Kemme, Michael R.] US Army Engn Res & Dev Ctr ERDC, CERL, Champaign, IL USA. RP Rood, MJ (reprint author), Univ Illinois, Dept Civil & Environm Engn, 205 N Mathews Ave, Urbana, IL 61801 USA. EM mrood@illinois.edu OI Yuen, Wangki/0000-0001-7612-7524 FU Strategic Environmental Research and Development Program (SERDP) [WP-1672] FX The authors thank Strategic Environmental Research and Development Program (SERDP Project WP-1672) for the funding of this project. NR 20 TC 1 Z9 1 U1 2 U2 13 PU TAYLOR & FRANCIS INC PI PHILADELPHIA PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA SN 1096-2247 EI 2162-2906 J9 J AIR WASTE MANAGE JI J. Air Waste Manage. Assoc. PD FEB 1 PY 2014 VL 64 IS 2 BP 227 EP 234 DI 10.1080/10962247.2013.851045 PG 8 WC Engineering, Environmental; Environmental Sciences; Meteorology & Atmospheric Sciences SC Engineering; Environmental Sciences & Ecology; Meteorology & Atmospheric Sciences GA 292JZ UT WOS:000329899300009 PM 24654390 ER PT J AU Teigler, JE Phogat, S Franchini, G Hirsch, VM Michael, NL Barouch, DH AF Teigler, Jeffrey E. Phogat, Sanjay Franchini, Genoveffa Hirsch, Vanessa M. Michael, Nelson L. Barouch, Dan H. TI The Canarypox Virus Vector ALVAC Induces Distinct Cytokine Responses Compared to the Vaccinia Virus-Based Vectors MVA and NYVAC in Rhesus Monkeys SO JOURNAL OF VIROLOGY LA English DT Article ID SIMIAN IMMUNODEFICIENCY; INFECTIOUS-DISEASES; HELA-CELLS; VACCINATION; CANDIDATES; SMALLPOX; STRAIN; PROTECTION; EFFICACY; TROPISM AB Despite the growing use of poxvirus vectors as vaccine candidates for multiple pathogens and cancers, their innate stimulatory properties remain poorly characterized. Here we show that the canarypox virus-based vector ALVAC induced distinct systemic proinflammatory and antiviral cytokine and chemokine levels following the vaccination of rhesus monkeys compared to the vaccinia virus-based vectors MVA and NYVAC. These data suggest that there are substantial biological differences among leading poxvirus vaccine vectors that may influence resultant adaptive immune responses following vaccination. C1 [Teigler, Jeffrey E.; Barouch, Dan H.] Beth Israel Deaconess Med Ctr, Ctr Virol & Vaccine Res, Boston, MA 02215 USA. [Teigler, Jeffrey E.; Barouch, Dan H.] MIT, Ragon Inst MGH, Boston, MA USA. [Teigler, Jeffrey E.; Barouch, Dan H.] Harvard, Boston, MA USA. [Phogat, Sanjay] Sanofi Pasteur Inc, Swiftwater, PA USA. [Franchini, Genoveffa] NCI, Bethesda, MD 20892 USA. [Hirsch, Vanessa M.] NIAID, Bethesda, MD 20892 USA. [Michael, Nelson L.] Walter Reed Army Inst Res, US Mil HIV Res Program, Bethesda, MD USA. RP Barouch, DH (reprint author), Beth Israel Deaconess Med Ctr, Ctr Virol & Vaccine Res, Boston, MA 02215 USA. EM dbarouch@bidmc.harvard.edu FU National Institutes of Health [AI078526, AI096040, AI095985]; U.S. Military HIV Research Program [W81XWH-07-2-0067]; Ragon Institute of MGH, MIT, and Harvard; National Defense Science & Engineering Graduate Fellowship; Herchel Smith Graduate Fellowship from Harvard University FX We acknowledge support from the National Institutes of Health (AI078526, AI096040, AI095985); the U.S. Military HIV Research Program (W81XWH-07-2-0067); and the Ragon Institute of MGH, MIT, and Harvard (D.H.B.); as well as a National Defense Science & Engineering Graduate Fellowship and the Herchel Smith Graduate Fellowship from Harvard University (J.E.T.). NR 36 TC 21 Z9 21 U1 0 U2 10 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA SN 0022-538X EI 1098-5514 J9 J VIROL JI J. Virol. PD FEB PY 2014 VL 88 IS 3 BP 1809 EP 1814 DI 10.1128/JVI.02386-13 PG 6 WC Virology SC Virology GA 291UU UT WOS:000329857000036 PM 24257612 ER PT J AU Verma, G Swami, A Chan, K AF Verma, Gunjan Swami, Ananthram Chan, Kevin TI The impact of competing zealots on opinion dynamics SO PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS LA English DT Article DE Zealotry; Opinion dynamics; Naming game ID CONSENSUS; ATTITUDE AB An individual's opinion on an issue is greatly impacted by others in his or her social network. Most people are open-minded and ready to change their opinion when presented evidence; however, some are zealots or inflexibles, that is, individuals who refuse to change their opinion while staunchly advocating an opinion in hopes of convincing others. Zealotry is present in opinions of significant personal investment, such as political, religious or corporate affiliation; it tends to be less commonplace in opinions involving rumors or fashion trends. In this paper, we examine the effect that zealots have in a population whose opinion dynamics obey the naming game model. We present numerical and analytical results about the number and nature of steady state solutions, demonstrating the existence of a bifurcation in the space of zealot fractions. Our analysis indicates conditions under which a minority zealot opinion ultimately prevails, and conditions under which neither opinion attains a majority. We also present numerical and simulation analysis of finite populations and on networks with partial connectivity. Published by Elsevier B.V. C1 [Verma, Gunjan; Swami, Ananthram; Chan, Kevin] Army Res Lab, Adelphi, MD 20783 USA. RP Verma, G (reprint author), Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM gunjan.verma.civ@mail.mil; ananthram.swami.civ@mail.mil; kevin.s.chan.civ@mail.mil NR 34 TC 12 Z9 12 U1 0 U2 16 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0378-4371 EI 1873-2119 J9 PHYSICA A JI Physica A PD FEB 1 PY 2014 VL 395 BP 310 EP 331 DI 10.1016/j.physa.2013.09.045 PG 22 WC Physics, Multidisciplinary SC Physics GA 292DG UT WOS:000329881800031 ER PT J AU Turalska, M West, BJ AF Turalska, M. West, B. J. TI Critical social networks SO PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS LA English DT Article DE Critical social states; Cooperation; Consensus; Entropy; Complex networks ID STATISTICS; MODEL AB Critical social ensembles are generated using a decision making model (DMM) consisting of a master equation, with two-state elements at the nodes of a two-dimensional lattice. The dynamics of the DMM undergo phase transitions to either a consensus state or another state composed of apparently statistically independent individuals as shown in an ensemble of calculations. The critical social ensemble is entailed by the network elements nonlinearly interacting through imperfect social imitation on the backbone of a correlation network. An information entropy measure of the difference between coherent and incoherent configurations in the critical social ensemble is constructed. The entropy indicates a greater probability for the formation of either opposing groups or universal consensus above that of random disagreement. (C) 2013 Elsevier B.V. All rights reserved. C1 [West, B. J.] US Army, Res Off, Informat Sci Directorate, Res Triangle Pk, NC 27709 USA. [Turalska, M.; West, B. J.] Duke Univ, Dept Phys, Durham, NC 27708 USA. RP Turalska, M (reprint author), Duke Univ, Dept Phys, Durham, NC 27708 USA. EM mat51@phy.duke.edu FU US Army Research Office FX The authors acknowledge the US Army Research Office for supporting this research. NR 22 TC 1 Z9 1 U1 0 U2 11 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0378-4371 EI 1873-2119 J9 PHYSICA A JI Physica A PD FEB 1 PY 2014 VL 395 BP 466 EP 475 DI 10.1016/j.physa.2013.10.033 PG 10 WC Physics, Multidisciplinary SC Physics GA 292DG UT WOS:000329881800045 ER PT J AU Darter, BJ Wilken, JM AF Darter, Benjamin J. Wilken, Jason M. TI Energetic consequences of using a prosthesis with adaptive ankle motion during slope walking in persons with a transtibial amputation SO PROSTHETICS AND ORTHOTICS INTERNATIONAL LA English DT Article DE Proprio; prosthetic feet; gait; amputee; oxygen consumption; microprocessor ID BELOW-KNEE AMPUTEES; TO-STEP TRANSITIONS; INCLINED WALKWAY; METABOLIC COST; GAIT; FOOT; FEET; MASS; PRINCIPLES; STIFFNESS AB Background: Technological advances in prosthetic design include the use of microprocessors that adapt device performance based on user motion. The Proprio ankle unit prepositions the foot to adjust for walking on slopes and increases foot clearance during swing to minimize gait deviations. Study design: Comparative analysis. Objectives: To investigate the effect of a prosthesis with adaptive ankle motion on physiological gait performance during slope walking. Methods: Six persons with a unilateral transtibial amputation completed treadmill walking tests at three slopes (-5 degrees, 0 degrees, and 5 degrees). The participants were tested wearing a customary device, active Proprio (Pon), and an identical inactivated Proprio (Poff). Results: Metabolic energy expenditure, energy cost for walking, and rating of walking difficulty were not statistically different between the Pon and Poff for all tested slopes. However, for slope descent, energy expenditure and energy cost for walking improved significantly by an average of 10%-14% for both the Pon and Poff compared to the customary limb. Rating of walking difficulty also showed an improvement with slope descent for both the Pon and Poff compared to the customary device. An improvement with slope ascent was found for Pon compared to the customary limb only. Conclusions: Adaptive ankle motion provided no meaningful physiological benefit during slope walking. The Proprio was, however, less demanding than the customary device for slope descent. Differences in the mechanical properties of the prosthetic feet likely contributed to the changes. Clinical relevance While the adaptive ankle motion did not affect metabolic energy expenditure or energy cost for walking, the results suggest close attention should be paid to the mechanical properties of the foot component. Assessment of gait on nonlevel surfaces is recommended to better understand the implications of different prosthetic design features. C1 [Darter, Benjamin J.] Virginia Commonwealth Univ, Dept Phys Therapy, Richmond, VA 23298 USA. [Wilken, Jason M.] Brooke Army Med Ctr, Dept Orthopaed & Rehabil, Ctr Intrepid, Ft Sam Houston, TX 78234 USA. RP Darter, BJ (reprint author), Virginia Commonwealth Univ, Dept Phys Therapy, 1200 East Broad St,POB 980224, Richmond, VA 23298 USA. EM bjdarter@vcu.edu OI Wilken, Jason/0000-0002-5556-7667 FU Military Amputee Research Program; CTSA award from the National Center for Advancing Translational Sciences [KL2TR000057] FX Support for this project was provided by the Military Amputee Research Program and by CTSA award No. KL2TR000057 from the National Center for Advancing Translational Sciences. NR 35 TC 9 Z9 9 U1 1 U2 13 PU SAGE PUBLICATIONS LTD PI LONDON PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND SN 0309-3646 EI 1746-1553 J9 PROSTHET ORTHOT INT JI Prosthet. Orthot. Int. PD FEB PY 2014 VL 38 IS 1 BP 5 EP 11 DI 10.1177/0309364613481489 PG 7 WC Orthopedics; Rehabilitation SC Orthopedics; Rehabilitation GA 291MB UT WOS:000329831700001 PM 23525888 ER PT J AU Liu, LB Liu, ZJ Xie, H Barrowes, B Bagtzoglou, AC AF Liu, Lanbo Liu, Zijian Xie, Hao Barrowes, Benjamin Bagtzoglou, Amvrossios C. TI Numerical simulation of UWB impulse radar vital sign detection at an earthquake disaster site SO AD HOC NETWORKS LA English DT Article DE Impulse radar; Ultra-wide band (UWB); Vital sign detection; Empirical mode decomposition (EMD); Earthquake hazard ID FREQUENCY AB Using the finite difference time domain (FDTD) numerical simulation approach and synthetic computational experiments we investigated the use of the ultra-wide band (UWB) radar technique for human vital sign detection under collapsed building debris caused by catastrophic earthquakes. The model of the collapsed building was developed based on a real situation from an earthquake disaster site. The model consists of two human beings with different characteristics of vital signs, i.e., with different cardio-respiration features, posed in different positions, and buried at different depths in the debris. Analysis of the synthetic data indicates that the UWB impulse radar can identify and separate the human subjects' vital sign for a radar record as short as 20 s. The simulation approach was verified with a physical experiment using impulse UWB radar with two human subjects positioned behind a concrete wall. Advanced signal processing of source separation and signal processing using empirical mode decomposition were conducted to identify and locate the human subjects. The results show that this approach is a promising technique for search and rescue of living victims at disaster sites. (C) 2012 Elsevier B.V. All rights reserved. C1 [Liu, Lanbo; Xie, Hao; Bagtzoglou, Amvrossios C.] Univ Connecticut, Dept Civil & Environm Engn, Storrs, CT 06260 USA. [Liu, Zijian] Univ Connecticut, Biomed Engn Program, Storrs, CT USA. [Barrowes, Benjamin] USACE, Cold Reg Res & Engn Lab, ERDC, Hanover, NH USA. RP Liu, LB (reprint author), Univ Connecticut, Dept Civil & Environm Engn, Storrs, CT 06260 USA. EM Lanbo.Liu@UConn.edu FU University of Connecticut Research Foundation; USACE Engineering Research and Development Center (ERDC) FX This study was supported by University of Connecticut Research Foundation, and partially supported by the USACE Engineering Research and Development Center (ERDC). NR 17 TC 8 Z9 8 U1 3 U2 16 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 1570-8705 EI 1570-8713 J9 AD HOC NETW JI Ad Hoc Netw. PD FEB PY 2014 VL 13 SI SI BP 34 EP 41 DI 10.1016/j.adhoc.2012.08.006 PN A PG 8 WC Computer Science, Information Systems; Telecommunications SC Computer Science; Telecommunications GA 288EN UT WOS:000329594900004 ER PT J AU Haehnel, R Buck, N Song, A AF Haehnel, Robert Buck, Nicole Song, Arnold TI Moisture effects on eolian particle entrainment SO ENVIRONMENTAL FLUID MECHANICS LA English DT Article DE Moisture; Eolian; Sediment transport; Soil ID FRICTION VELOCITY; SURFACE MOISTURE; CAPILLARY FORCE; SOIL-MOISTURE; WIND-EROSION; THRESHOLD; SAND AB In wind tunnel experiments, we study the effects of soil moisture on the threshold condition to entrain fine grain sand/silt into eolian flow and the near-bed concentration of airborne particles. To study the effect of particle shape on moisture bonding, we use two types of particles nearly equal in size: spherical glass beads and sieved quartz sand . Both are poorly graded soils. We conducted these experiments at low moisture contents . We found that the spherical particles were more sensitive to changes in moisture than the sand, attributable to the large differences in specific surface area of the two particles. The larger specific surface area for sand is due to the surface roughness of the angular sand particle. Consequently, sand "stores" more moisture via surface adsorption, requiring higher soil moisture content to form liquid bridges between sand particles. Based on these findings, we extend the concept of a threshold moisture content, -originally proposed for clayey soils-to soils that lack any measureable clay content. This allows application of existing models developed for clayey soils that quantify the moisture effect on the threshold friction velocity to sand and silty soils (i.e., clay content 0). Additionally, we develop a model that quantifies the moisture effects on near-surface airborne particulate concentration, using experimental observations to determine the functional dependence on fluid and particle properties, including soil specific area. These models can be applied to numerical simulation of particulate plume formation and dispersion. C1 [Haehnel, Robert; Song, Arnold] US Army, Cold Reg Res & Engn Lab, Engineer Res & Dev Ctr, Hanover, NH 03755 USA. [Buck, Nicole] Dartmouth Coll, Hanover, NH 03755 USA. RP Haehnel, R (reprint author), US Army, Cold Reg Res & Engn Lab, Engineer Res & Dev Ctr, 72 Lyme Rd, Hanover, NH 03755 USA. EM Robert.B.Haehnel@usace.army.mil NR 32 TC 0 Z9 0 U1 4 U2 21 PU SPRINGER PI DORDRECHT PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS SN 1567-7419 EI 1573-1510 J9 ENVIRON FLUID MECH JI Environ. Fluid Mech. PD FEB PY 2014 VL 14 IS 1 BP 135 EP 156 DI 10.1007/s10652-013-9299-y PG 22 WC Environmental Sciences; Mechanics; Meteorology & Atmospheric Sciences; Oceanography; Water Resources SC Environmental Sciences & Ecology; Mechanics; Meteorology & Atmospheric Sciences; Oceanography; Water Resources GA 288UL UT WOS:000329637300007 ER PT J AU Bozic, RG West, AC AF Bozic, Robert G. West, Alan C. TI Electrochemical detection of 14 common munitions constituents SO JOURNAL OF APPLIED ELECTROCHEMISTRY LA English DT Article DE Electrochemical detection; Munitions constituents; Square wave voltammetry ID SELF-ASSEMBLED MONOLAYERS; ELECTRODES; 2,4,6-TRINITROTOLUENE; EXPLOSIVES; NITRO; GOLD AB Electrochemical detections of 14 munitions constituents (MCs) listed on the Environmental Protection Agency hazardous waste list were examined using square wave voltammetry. Of the MCs that showed peak resolution in the scanned range, the reduction potential, limit of detection and limit of quantitation are reported here. The MCs tested are in three groups: nitrobenzenes, nitrotoluenes, and other nitro-aromatics: tetryl, HMX, and RDX. There was a correlation between peak resolution and the number of nitro groups for the nitrobenzenes and nitrotoluenes. The nitro group distance from the methyl for the nitrotoluenes with two nitro groups showed some correlation to the ability to detect as well. Some mixture experiments were conducted in which MCs with three and two nitro groups were detected simultaneously. While tetryl readily displayed two peaks, RDX and HMX did not show such clear peak resolution. C1 [Bozic, Robert G.] US Mil Acad, Dept Chem & Life Sci, West Point, NY 10996 USA. [Bozic, Robert G.; West, Alan C.] Columbia Univ, Dept Chem Engn, New York, NY 10027 USA. RP Bozic, RG (reprint author), US Mil Acad, Dept Chem & Life Sci, West Point, NY 10996 USA. EM rb2335@columbia.edu FU U.S. Army Engineer Research and Development Center, Vicksburg, Mississippi [W912HZ-06-C-0034] FX This work was supported by the U.S. Army Engineer Research and Development Center, Vicksburg, Mississippi Contract Number W912HZ-06-C-0034. The following cadets and former cadets of the US Military Academy and former student of Columbia University are gratefully recognized for their lab work on this project: Greg Walker, Aaron Devig, Henry Harpen, Gordon Shu, Jeffery Chin, Seth Johnson, Erik Moore, Branko Kovacevic, Nathan Held, Lauren Ng, Aaron Beyea, Harrison Heath, Zach Bowers, and Brian Albert. NR 19 TC 0 Z9 0 U1 0 U2 17 PU SPRINGER PI DORDRECHT PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS SN 0021-891X EI 1572-8838 J9 J APPL ELECTROCHEM JI J. Appl. Electrochem. PD FEB PY 2014 VL 44 IS 2 BP 293 EP 300 DI 10.1007/s10800-013-0624-4 PG 8 WC Electrochemistry SC Electrochemistry GA 289AJ UT WOS:000329653100009 ER PT J AU Cordova, CB Owens, BD AF Cordova, Christopher B. Owens, Brett D. TI Infraspinatus muscle atrophy from suprascapular nerve compression SO JAAPA-JOURNAL OF THE AMERICAN ACADEMY OF PHYSICIAN ASSISTANTS LA English DT Article DE infraspinatus muscle atrophy; suprascapular nerve compression; posterior labral tear; paralabral cyst; spinoglenoid notch; orthopedics ID SPINOGLENOID NOTCH; ENTRAPMENT AB Muscle weakness without pain may signal a nerve compression injury. Because these injuries should be identified and treated early to prevent permanent muscle weakness and atrophy, providers should consider suprascapular nerve compression in patients with shoulder muscle weakness. C1 [Cordova, Christopher B.] Keller Army Community Hosp, Practices Orthoped, West Point, NY 10996 USA. [Owens, Brett D.] Keller Army Community Hosp, Orthoped Surg, West Point, NY USA. RP Cordova, CB (reprint author), Keller Army Community Hosp, Practices Orthoped, West Point, NY 10996 USA. NR 5 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA SN 1547-1896 EI 0893-7400 J9 JAAPA-J AM ACAD PHYS JI JAAPA-J. Am. Acad. Physician Assist. PD FEB PY 2014 VL 27 IS 2 BP 33 EP 35 DI 10.1097/01.JAA.0000442701.87975.42 PG 3 WC Medicine, General & Internal SC General & Internal Medicine GA CM3GB UT WOS:000357568900007 PM 24463748 ER PT J AU Chaitaveep, N Utachee, P Nakamura, S Chuenchitra, T Ekpo, P Takeda, N Pattanapanyasat, K Kameoka, M AF Chaitaveep, Nithinart Utachee, Piraporn Nakamura, Shota Chuenchitra, Thippawan Ekpo, Pattama Takeda, Naokazu Pattanapanyasat, Kovit Kameoka, Masanori TI Characterization of human immunodeficiency virus type 1 CRF01_AE env genes derived from recently infected Thai individuals SO MICROBES AND INFECTION LA English DT Article DE Recent HIV-1 infection; Transmitted/founder virus; CRF01_AE; Envelope glycoproteins; Neutralization; Captured BED-ELISA ID BROADLY NEUTRALIZING ANTIBODIES; HUMAN MONOCLONAL-ANTIBODIES; HIV-1 INFECTION; SMALL-MOLECULE; CLADE-B; TRANSMISSION; GP41; INHIBITOR; ENTRY; SEROCONVERSION AB Transmitted/founder virus is responsible for the establishment of human immunodeficiency virus type 1 (HIV-1) infection and induces primary anti-HIV-1 immune responses; therefore, it is important to study the viral population to understand the early events of HIV-1 infection. We amplified HIV-1 env genes from sera derived from recently infected Thai individuals, and established envelope glycoproteins (Env)-re-combinant viruses. Generated Env-recombinant viruses were tested for their neutralization susceptibility to neutralizing human monoclonal antibodies (NHMAbs) and entry inhibitors, as well as being subjected to genotypic analysis. Most recombinant viruses were susceptible to neutralization by NHMAbs to Env gp41, whereas approximately one-third of the recombinant viruses were susceptible to a NHMAb against the CD4 binding site of gp120. In addition, all env genes were classified into CRF01_AE genes and showed low genetic divergence. Taken together with our previous studies on CRF01_AE env genes derived from chronically infected Thai individuals, these results suggested that the immunological and genetic characteristics of CRF01_AE Env derived from recently infected Thai individuals were different from those derived from chronically infected individuals. (C) 2013 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved. C1 [Chaitaveep, Nithinart] Mahidol Univ, Siriraj Hosp, Fac Med, Grad Program Immunol, Bangkok 10700, Thailand. [Chaitaveep, Nithinart; Chuenchitra, Thippawan] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand. [Utachee, Piraporn; Takeda, Naokazu; Kameoka, Masanori] Thailand Japan Res Collaborat Ctr Emerging & Reem, Nonthaburi, Thailand. [Nakamura, Shota; Takeda, Naokazu; Kameoka, Masanori] Osaka Univ, Microbial Dis Res Inst, Osaka, Japan. [Ekpo, Pattama; Pattanapanyasat, Kovit] Mahidol Univ, Dept Immunol, Fac Med, Siriraj Hosp, Bangkok 10700, Thailand. [Kameoka, Masanori] Kobe Univ, Grad Sch Hlth Sci, Dept Int Hlth, Suma Ku, Kobe, Hyogo 6540142, Japan. RP Kameoka, M (reprint author), Kobe Univ, Grad Sch Hlth Sci, Dept Int Hlth, Suma Ku, 7-10-2 Tomogaoka, Kobe, Hyogo 6540142, Japan. EM mkameoka@port.kobe-u.ac.jp OI Kameoka, Masanori/0000-0001-5525-9915 FU program of the Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) by the Ministry of Education, Culture, Sports, Science and Technology of Japan FX We are grateful to Major General Boonyarak Poonchai, a Former Director of AFRIMS, Thailand, for his valuable help with this study. This work was supported in part by the program of the Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) by the Ministry of Education, Culture, Sports, Science and Technology of Japan. This work was a part of Ph.D. program to Nithinart Chaitaveep, and the opinions or assertions presented in the article are the private views of the authors and are not to be constructed as reflecting the official positions of the Royal Thai Army. TAK-779, T-20, U87.CD4.CXCR4 and U87.CD4.CCR5 were obtained through the AIDS Research and Reference Reagent Program, Division of AIDS, MAID, NIH. The manuscript was proofread by Medical English Service (Kyoto, Japan). NR 50 TC 1 Z9 2 U1 1 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 1286-4579 EI 1769-714X J9 MICROBES INFECT JI Microbes Infect. PD FEB PY 2014 VL 16 IS 2 BP 142 EP 152 DI 10.1016/j.micinf.2013.10.015 PG 11 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA AY9JM UT WOS:000347866300007 PM 24513704 ER PT J AU Yang, J Bowman, PD Kerwin, SM Stavchansky, S AF Yang, John Bowman, Phillip D. Kerwin, Sean M. Stavchansky, Salomon TI Development and validation of an LCMS method to determine the pharmacokinetic profiles of caffeic acid phenethyl amide and caffeic acid phenethyl ester in male Sprague-Dawley rats SO BIOMEDICAL CHROMATOGRAPHY LA English DT Article DE caffeic acid phenethyl amide; caffeic acid phenethyl ester; pharmacokinetics; LCMS; Sprague-Dawley rats ID CYCLOOXYGENASE ACTIVITY; KAPPA-B; CELLS; CAPE; PROPOLIS; INJURY; EXPRESSION; INHIBITOR; STABILITY; ANALOGS AB A validated LCMS method was developed for the quantitative determination of caffeic acid phenethyl amide (CAPA) and caffeic acid phenethyl ester (CAPE) from rat plasma. Separation was achieved using a reverse-phase C-12 HPLC column (150 x 2.00 mm, 4 mu m) with gradient elution running water (A) and acetonitrile (B). Mass spectrometry was performed with electrospray ionization in negative mode. This method was used to determine the pharmacokinetic profiles of CAPA and CAPE in male Sprague-Dawley rats following intravenous bolus administration of 5, 10 and 20 mg/kg of CAPA and 20 mg/kg of CAPE. The pharmacokinetic analysis suggests the lack of dose proportionality in the dose range of 5-20 mg/kg of CAPA. Total clearance values for CAPA ranged from 45 to 156 mL/min and decreased with increasing dose of CAPA. The volume of distribution for CAPA ranged from 17,750 to 52,420 mL, decreasing with increasing dose. The elimination half-life for CAPA ranged from 243.1 to 295.8 min and no statistically significant differences were observed between dose groups in the range of 5-20 mg/kg (p > 0.05). The elimination half-life for CAPE was found to be 92.26 min. Copyright (c) 2013 John Wiley & Sons, Ltd. C1 [Yang, John; Kerwin, Sean M.; Stavchansky, Salomon] Univ Texas Austin, Austin, TX 78712 USA. [Bowman, Phillip D.] US Army, Inst Surg Res, San Antonio, TX USA. RP Stavchansky, S (reprint author), Univ Texas Austin, Austin, TX 78712 USA. EM stavchansky@mail.utexas.edu OI Kerwin, Sean/0000-0001-8432-6558 NR 23 TC 3 Z9 3 U1 3 U2 24 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0269-3879 EI 1099-0801 J9 BIOMED CHROMATOGR JI Biomed. Chromatogr. PD FEB PY 2014 VL 28 IS 2 BP 241 EP 246 DI 10.1002/bmc.3011 PG 6 WC Biochemical Research Methods; Biochemistry & Molecular Biology; Chemistry, Analytical; Pharmacology & Pharmacy SC Biochemistry & Molecular Biology; Chemistry; Pharmacology & Pharmacy GA 286CZ UT WOS:000329443900008 PM 23982887 ER PT J AU Brady, JJ Farrell, ME Pellegrino, PM AF Brady, John J. Farrell, Mikella E. Pellegrino, Paul M. TI Discrimination of chemical warfare simulants via multiplex coherent anti-Stokes Raman scattering and multivariate statistical analysis SO OPTICAL ENGINEERING LA English DT Article DE Raman scattering; CARS; femtosecond; simulants; chemical warfare; classification; PCA ID INDUCED BREAKDOWN SPECTROSCOPY; CARS SPECTROSCOPY; SPECTRA; MICROSCOPY; STANDOFF AB Multiplex coherent anti-Stokes Raman scattering (MCARS) is used to detect several chemical warfare simulants, such as dimethyl methylphosphonate and 2-chloroethyl ethyl sulfide, with high specificity. The spectral bandwidth of the femtosecond laser pulse used in these studies is sufficient to coherently and simultaneously drive all the vibrational modes in the molecule of interest. Evidence shows that MCARS is capable of overcoming common sensitivity limitations of spontaneous Raman scattering, thus allowing for the detection of the target material in milliseconds with standard, uncooled universal serial bus spectrometers as opposed to seconds with cooled, intensified CCD-based spectrometers. In addition, the obtained MCARS spectrum of the investigated sample provides multiple unique signatures. These signatures are used in an off-line multivariate statistical analysis allowing for the material's discrimination with high fidelity. (C) 2014 Society of Photo-Optical Instrumentation Engineers (SPIE) C1 [Brady, John J.; Farrell, Mikella E.; Pellegrino, Paul M.] US Army Res Lab, RDRL SEE E, Adelphi, MD 20783 USA. RP Brady, JJ (reprint author), US Army Res Lab, RDRL SEE E, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM paul.m.pellegrino.civ@mail.mil FU United States Army Research Laboratory [W911NF-12-2-0019] FX Research was sponsored by the United States Army Research Laboratory and was accomplished under cooperative agreement number W911NF-12-2-0019. The views and conclusions contained in this document are those of the authors and should not be interpreted as representing the official policies, either expressed or implied, of the United States Army Research Laboratory or the United States government. The United States Government is authorized to reproduce and distribute reprints for government purposes notwithstanding any copyright notation herein. NR 33 TC 1 Z9 1 U1 1 U2 44 PU SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98225 USA SN 0091-3286 EI 1560-2303 J9 OPT ENG JI Opt. Eng. PD FEB PY 2014 VL 53 IS 2 AR 021105 DI 10.1117/1.OE.53.2.021105 PG 8 WC Optics SC Optics GA 287GA UT WOS:000329528600004 ER PT J AU Liu, KC Ghoshal, A AF Liu, Kuang C. Ghoshal, Anindya TI Validity of random microstructures simulation in fiber-reinforced composite materials SO COMPOSITES PART B-ENGINEERING LA English DT Article DE Microstructures; Micro-mechanics; Statistical properties/methods; Computational modeling; Randomness ID REPRESENTATIVE VOLUME ELEMENTS; QUANTITATIVE CHARACTERIZATION; ELASTIC PROPERTIES; DISTRIBUTED FIBERS; GENERATION; MORPHOLOGY; INITIATION; MATRIX; DAMAGE; MEDIA AB This paper establishes a set of criteria to check two microstructures in fiber-reinforced composites for geometrical equivalence. The criteria are based on a combination of a point process, one-point and two-point probability functions; convergence of microstructure size; and equality of fiber radius distribution. The criteria were shown to distinguish different microstructures and identify similar ones. Also, a reconstruction technique is proposed that can efficiently reconstruct a microstructure while satisfying the criteria. Results show the reconstruction technique exceeded the 5% tolerances set by multiple samples of an experimental observation. (C) 2013 Elsevier Ltd. All rights reserved. C1 [Liu, Kuang C.; Ghoshal, Anindya] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Liu, KC (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. EM kcliu@asu.edu NR 34 TC 4 Z9 4 U1 2 U2 19 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 1359-8368 EI 1879-1069 J9 COMPOS PART B-ENG JI Compos. Pt. B-Eng. PD FEB PY 2014 VL 57 BP 56 EP 70 DI 10.1016/j.compositesb.2013.08.006 PG 15 WC Engineering, Multidisciplinary; Materials Science, Composites SC Engineering; Materials Science GA 277EG UT WOS:000328801200009 ER PT J AU Patel, VM Easley, GR Chellappa, R Nasrabadi, NM AF Patel, Vishal M. Easley, Glenn R. Chellappa, Rama Nasrabadi, Nasser M. TI Separated Component-Based Restoration of Speckled SAR Images SO IEEE TRANSACTIONS ON GEOSCIENCE AND REMOTE SENSING LA English DT Article DE Image restoration; multiplicative noise; speckle; synthetic aperture radar ID BAYESIAN WAVELET SHRINKAGE; MULTIPLICATIVE NOISE; VARIATIONAL APPROACH; REMOVAL; REPRESENTATIONS; DECOMPOSITION; ALGORITHM; SIGNAL; MODEL AB Many coherent imaging modalities such as synthetic aperture radar suffer from a multiplicative noise, commonly referred to as speckle, which often makes the interpretation of data difficult. An effective strategy for speckle reduction is to use a dictionary that can sparsely represent the features in the speckled image. However, such approaches fail to capture important salient features such as texture. In this paper, we present a speckle reduction algorithm that handles this issue by formulating the restoration problem so that the structure and texture components can be separately estimated with different dictionaries. To solve this formulation, an iterative algorithm based on surrogate functionals is proposed. Experiments indicate the proposed method performs favorably compared to state-of-the-art speckle reduction methods. C1 [Patel, Vishal M.; Chellappa, Rama] Univ Maryland, Dept Elect & Comp Engn, College Pk, MD 20742 USA. [Patel, Vishal M.; Chellappa, Rama] Univ Maryland, Ctr Automat Res, UMI ACS, College Pk, MD 20742 USA. [Easley, Glenn R.] Univ Maryland, Norbert Wiener Ctr, Dept Math, College Pk, MD 20742 USA. [Nasrabadi, Nasser M.] US Army, Res Lab, Adelphi, MD 20783 USA. RP Patel, VM (reprint author), Univ Maryland, Dept Elect & Comp Engn, College Pk, MD 20742 USA. EM pvishalm@umiacs.umd.edu; geasley@math.umd.edu; rama@umiacs.umd.edu; nasser.m.nasrabadi@us.army.mil FU Army Research Office MURI [W911NF0910383] FX The work of V. M. Patel and R. Chellappa was supported by the Army Research Office MURI under Grant W911NF0910383. NR 46 TC 7 Z9 7 U1 0 U2 6 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0196-2892 EI 1558-0644 J9 IEEE T GEOSCI REMOTE JI IEEE Trans. Geosci. Remote Sensing PD FEB PY 2014 VL 52 IS 2 BP 1019 EP 1029 DI 10.1109/TGRS.2013.2246794 PG 11 WC Geochemistry & Geophysics; Engineering, Electrical & Electronic; Remote Sensing; Imaging Science & Photographic Technology SC Geochemistry & Geophysics; Engineering; Remote Sensing; Imaging Science & Photographic Technology GA 279DT UT WOS:000328941300020 ER PT J AU Ferguson, JB Tabandeh-Khorshid, M Rohatgi, PK Cho, K Kim, CS AF Ferguson, J. B. Tabandeh-Khorshid, Meysam Rohatgi, Pradeep K. Cho, Kyu Kim, Chang-Soo TI Predicting tensile and compressive mechanical properties of bimodal nano-aluminum alloys SO SCRIPTA MATERIALIA LA English DT Article DE Aluminum alloys; Nanocrystalline metal; Analytical methods; Mechanical properties ID BEHAVIOR; COMPOSITE; STRENGTH; DUCTILITY AB We present a new analytical model for predicting the tensile and compressive mechanical properties of bimodal nano-aluminum alloys. The model relies on simple material variables that show a Hall-Petch-like grain size dependence including a newly defined ductility parameter which can be used with the Hollomon equation to allow for the prediction of failure stress and strain. When the model is applied to bimodal nano-aluminum alloys, the results show excellent agreement with the experimental observations. (C) 2013 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved. C1 [Ferguson, J. B.; Tabandeh-Khorshid, Meysam; Rohatgi, Pradeep K.; Kim, Chang-Soo] Univ Wisconsin, Mat Sci & Engn Dept, Milwaukee, WI 53211 USA. [Cho, Kyu] US Army Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. RP Kim, CS (reprint author), Univ Wisconsin, Mat Sci & Engn Dept, Milwaukee, WI 53211 USA. EM kimcs@uwm.edu FU US Army Research Laboratory [W911NF-08-2-0014] FX This material is based upon work supported by the US Army Research Laboratory under Cooperative Agreement No. W911NF-08-2-0014. The views, opinions, and conclusions made in this document are those of the authors and should not be interpreted as representing the official policies, either expressed or implied, of Army Research Laboratory or the US Government. The US Government is authorized to reproduce and distribute reprints for Government purposes notwithstanding any copyright notation herein. NR 11 TC 7 Z9 7 U1 2 U2 21 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 1359-6462 J9 SCRIPTA MATER JI Scr. Mater. PD FEB PY 2014 VL 72-73 BP 13 EP 16 DI 10.1016/j.scriptamat.2013.10.005 PG 4 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering SC Science & Technology - Other Topics; Materials Science; Metallurgy & Metallurgical Engineering GA 282CS UT WOS:000329148500004 ER PT J AU Kesavan, JS Bottiger, JR Schepers, DR McFarland, AR AF Kesavan, Jana S. Bottiger, Jerold R. Schepers, Deborah R. McFarland, Andrew R. TI Comparison of Particle Number Counts Measured with an Ink Jet Aerosol Generator and an Aerodynamic Particle Sizer SO AEROSOL SCIENCE AND TECHNOLOGY LA English DT Article ID EFFICIENCY AB Aerodynamic particle sizer (APS) users typically calibrate the particle sizing capabilities, but not the counting efficiency upon which aerosol concentration results are based. Herein, comparisons were made between the counts provided by an ink jet aerosol generator (IJAG) with those measured by an APS. Near-monodisperse (geometric standard deviation of about 1.06) liquid or solid aerosols in the size range of 0.95 to 13.3m aerodynamic diameter (AD) generated with an IJAG were released into the inner inlet-tube of the APS in a manner that rendered APS wall and aspiration losses negligible. For most experiments, the IJAG generated 75 particles/s, which rate was maintained by the IJAG system through control of electrical pulses applied to its ink jet cartridge. For particles in the size range of 2-13.3m AD, the ratio of relative detection efficiency (ratio of the number of particles counted by the APS to the number reported as generated by the IJAG) was 99.3 1.4%; however, for test particles between 0.95 and 2m AD, the relative detection efficiency was somewhat lower, but the drop off was less than about 2%. This slight drop off is likely associated with the light scattering detection approach and corresponding counting algorithm of the APS. Tests were conducted where the IJAG produced 7.0m AD particles at rates of 1 to 500s(-1) and the results showed essentially a 1:1 correspondence between IJAG and APS counts. The presence of smaller-sized background particles did not affect the measured APS counts of larger-sized challenge particles. C1 [Kesavan, Jana S.; Bottiger, Jerold R.] US Army, Edgewood Chem Biol Ctr, Aerosol Sci Branch, Aberdeen Proving Ground, MD 21005 USA. [Bottiger, Jerold R.; Schepers, Deborah R.] Excet Inc, Springfield, VA USA. [McFarland, Andrew R.] PE Inc, Houston, TX USA. RP Kesavan, JS (reprint author), US Army, Edgewood Chem Biol Ctr, Aerosol Sci Branch, Aberdeen Proving Ground, MD 21005 USA. EM jana.kesavan@us.army.mil NR 22 TC 2 Z9 2 U1 3 U2 15 PU TAYLOR & FRANCIS INC PI PHILADELPHIA PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA SN 0278-6826 EI 1521-7388 J9 AEROSOL SCI TECH JI Aerosol Sci. Technol. PD FEB 1 PY 2014 VL 48 IS 2 BP 219 EP 227 DI 10.1080/02786826.2013.868594 PG 9 WC Engineering, Chemical; Engineering, Mechanical; Environmental Sciences; Meteorology & Atmospheric Sciences SC Engineering; Environmental Sciences & Ecology; Meteorology & Atmospheric Sciences GA 278GQ UT WOS:000328877600011 ER PT J AU Hristozov, DR Zabeo, A Foran, C Isigonis, P Critto, A Marcomini, A Linkov, I AF Hristozov, Danail R. Zabeo, Alex Foran, Christy Isigonis, Panagiotis Critto, Andrea Marcomini, Antonio Linkov, Igor TI A weight of evidence approach for hazard screening of engineered nanomaterials SO NANOTOXICOLOGY LA English DT Article DE engineered nanomaterials; titanium dioxide nanoparticles; human health hazard screening; weight of evidence; multi-criteria decision analysis ID TITANIUM-DIOXIDE NANOPARTICLES; MULTICRITERIA DECISION-ANALYSIS; ENVIRONMENTAL RISK-ASSESSMENT; CHRONIC INHALATION EXPOSURE; ULTRAFINE PARTICLE TYPES; IN-VITRO; LUNG INJURY; PULMONARY RESPONSE; TIO2 NANOPARTICLES; EPITHELIAL-CELLS AB Hazard identification is an important step in assessing nanomaterial risk and is required under multiple regulatory frameworks in the US, Europe and worldwide. Given the emerging nature of the field and complexity of nanomaterials, multiple studies on even basic material properties often result in varying data pointing in different directions when data interpretation is attempted. Weight of evidence (WOE) evaluation has been recommended for nanomaterial risk assessment, but the majority of WOE frameworks are qualitative in nature and do not satisfy the growing needs for objectivity and transparency that are necessary for regulatory decision making. This paper implements a quantitative WOE framework that utilizes multi-criteria decision analysis methodology for integrating individual studies on nanomaterial hazard resulting from physico-chemical and toxicological properties of nanomaterials. For the first time, a WOE approach explicitly integrates expert evaluation of data quality of available information. Application of the framework is illustrated for titanium dioxide nanoparticles (nano-TiO2), but the approach is designed to compare the relative hazard of several nanomaterials as well as emerging stressors in general. C1 [Hristozov, Danail R.; Zabeo, Alex; Isigonis, Panagiotis; Critto, Andrea; Marcomini, Antonio] Univ Ca Foscari Venice, Dept Environm Sci Informat & Stat, Venice, Italy. [Foran, Christy; Linkov, Igor] US Army, Engineer Res & Dev Ctr, Corps Engineers, Concord, MA 01742 USA. RP Linkov, I (reprint author), US Army, Engineer Res & Dev Ctr, Corps Engineers, 696 Virginia Rd, Concord, MA 01742 USA. EM Igor.Linkov@usace.army.mil RI Zabeo, Alex/D-6715-2014; OI Zabeo, Alex/0000-0001-7162-5364; Critto, Andrea/0000-0001-8868-9057; Hristozov, Danail/0000-0002-2386-7366; Isigonis, Panagiotis/0000-0002-8404-7708 FU US Army Engineer Research and Development Center Nanotechnology Focus Area; EU FP7 ENPRA Project [NMP4-SL-2009-228789] FX We would like to thank Professor Jeffery Keisler and Mr. Matthew Bates for helpful discussions. This study was funded in part by the US Army Engineer Research and Development Center Nanotechnology Focus Area and EU FP7 ENPRA Project (NMP4-SL-2009-228789). Permission was granted by the Chief of Engineers to publish this information. The views and opinions expressed in this paper are those of the individual authors and not those of the US Army or other sponsor agencies. NR 108 TC 21 Z9 22 U1 3 U2 45 PU INFORMA HEALTHCARE PI NEW YORK PA 52 VANDERBILT AVE, NEW YORK, NY 10017 USA SN 1743-5390 EI 1743-5404 J9 NANOTOXICOLOGY JI Nanotoxicology PD FEB PY 2014 VL 8 IS 1 BP 72 EP 87 DI 10.3109/17435390.2012.750695 PG 16 WC Nanoscience & Nanotechnology; Toxicology SC Science & Technology - Other Topics; Toxicology GA 267UP UT WOS:000328124100007 PM 23153309 ER PT J AU Whittington, WR Oppedal, AL Turnage, S Hammi, Y Rhee, H Allison, PG Crane, CK Horstemeyer, MF AF Whittington, W. R. Oppedal, A. L. Turnage, S. Hammi, Y. Rhee, H. Allison, P. G. Crane, C. K. Horstemeyer, M. F. TI Capturing the effect of temperature, strain rate, and stress state on the plasticity and fracture of rolled homogeneous armor (RHA) steel SO MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING LA English DT Article DE High strain rate; High temperature; Stress state; Damage; Structure-property relationship ID DEFORMATION; METALS; MODEL AB This work is an investigation of the mechanical response and damage evolution of Rolled Homogeneous Armor (RHA) steel at different temperatures, stress states, and strain rates. Although the tension, compression, and torsion yield and work hardening rates were essentially the same when considering uncertainty in the tests, the damage progression and failure strains were different. Tension and torsion experiments revealed that torsional loading was more deleterious to ductility when comparing equivalent failure strains. As is typical of metals, the experiments showed that as the temperature increased to 300 C from ambient conditions, the flow stress decreased, and the failure strains increased. High strain-rate experiments conducted via split-Hopkinson pressure bars (Kolsky) showed increased strength and reduced failure strains. Fractography was performed on selected tension and torsion postmortem specimens to quantify the number density of nucleated voids and size distribution of voids from the experiments. For the first time in the literature, an internal state variable (ISV) plasticity/damage model was used to capture the varying effects of temperature, strain rate, and stress state for the RHA steel with a single set of plasticity and damage parameters. The ISV model for RHA steel can be used in finite element analysis (FEA) under a wide variety of boundary conditions. (C) 2013 Elsevier B.V. All rights reserved. C1 [Whittington, W. R.; Oppedal, A. L.; Turnage, S.; Hammi, Y.; Rhee, H.; Horstemeyer, M. F.] Mississippi State Univ, Ctr Adv Vehicular Syst, Starkville, MS 39762 USA. [Allison, P. G.; Crane, C. K.] US Army, Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. [Horstemeyer, M. F.] Mississippi State Univ, Dept Mech Engn, Mississippi State, MS 39762 USA. RP Whittington, WR (reprint author), Mississippi State Univ, Ctr Adv Vehicular Syst, 200 Res Blvd, Starkville, MS 39762 USA. EM wrw51@cavs.msstate.edu; aoppedal@cavs.msstate.edu; scottturnage@gmail.com; yhammi@cavs.msstate.edu; hrhee@cavs.msstate.edu; Paul.G.Allison@erdc.dren.mil; Charles.K.Crane@usace.army.mil; mfhorst@cavs.msstate.edu OI Allison, Paul/0000-0002-9041-237X; Horstemeyer, Mark/0000-0003-4230-0063 FU US Army Engineer Research Development Center (ERDC) from the Department of Homeland Security (DHS) [W912HZ-11-C-0021] FX This work was performed at Mississippi State University's Center for Advanced Vehicular Systems (CAVS) and was funded by the US Army Engineer Research Development Center (ERDC) under Grant W912HZ-11-C-0021 from the Department of Homeland Security (DHS). The authors graciously thank Ric Carino for assistance using the DMGfit software. Permission to publish was granted by the Director of the Geotechnical and Structures Laboratory. NR 15 TC 3 Z9 3 U1 1 U2 11 PU ELSEVIER SCIENCE SA PI LAUSANNE PA PO BOX 564, 1001 LAUSANNE, SWITZERLAND SN 0921-5093 EI 1873-4936 J9 MAT SCI ENG A-STRUCT JI Mater. Sci. Eng. A-Struct. Mater. Prop. Microstruct. Process. PD JAN 31 PY 2014 VL 594 BP 82 EP 88 DI 10.1016/j.msea.2013.11.018 PG 7 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering SC Science & Technology - Other Topics; Materials Science; Metallurgy & Metallurgical Engineering GA AB3FW UT WOS:000331677700012 ER PT J AU Wijayalath, W Majji, S Kleschenko, Y Pow-Sang, L Brumeanu, TD Villasante, EF Vasta, GR Fernandez-Robledo, JA Casares, S AF Wijayalath, Wathsala Majji, Sai Kleschenko, Yuliya Pow-Sang, Luis Brumeanu, Teodor D. Villasante, Eileen Franke Vasta, Gerardo R. Fernandez-Robledo, Jose-Antonio Casares, Sofia TI Humanized HLA-DR4 Mice Fed with the Protozoan Pathogen of Oysters Perkinsus Marinus (Dermo) Do Not Develop Noticeable Pathology but Elicit Systemic Immunity SO PLOS ONE LA English DT Article ID SUBUNIT RIBOSOMAL-RNA; CRASSOSTREA-VIRGINICA; EASTERN OYSTER; RAW OYSTERS; PHYLUM APICOMPLEXA; CHESAPEAKE BAY; PARASITE; CELLS; GENE; TRANSMISSION AB Perkinsus marinus (Phylum Perkinsozoa) is a marine protozoan parasite responsible for "Dermo" disease in oysters, which has caused extensive damage to the shellfish industry and estuarine environment. The infection prevalence has been estimated in some areas to be as high as 100%, often causing death of infected oysters within 1-2 years post-infection. Human consumption of the parasites via infected oysters is thus likely to occur, but to our knowledge the effect of oral consumption of P. marinus has not been investigated in humans or other mammals. To address the question we used humanized mice expressing HLA-DR4 molecules and lacking expression of mouse MHC-class II molecules (DR4.EA(0)) in such a way that CD4 T cell responses are solely restricted by the human HLA-DR4 molecule. The DR4.EA(0) mice did not develop diarrhea or any detectable pathology in the gastrointestinal tract or lungs following single or repeated feedings with live P. marinus parasites. Furthermore, lymphocyte populations in the gut associated lymphoid tissue and spleen were unaltered in the parasite-fed mice ruling out local or systemic inflammation. Notably, naive DR4.EA(0) mice had antibodies (IgM and IgG) reacting against P. marinus parasites whereas parasite specific T cell responses were undetectable. Feeding with P. marinus boosted the antibody responses and stimulated specific cellular (IFN gamma) immunity to the oyster parasite. Our data indicate the ability of P. marinus parasites to induce systemic immunity in DR4.EA(0) mice without causing noticeable pathology, and support rationale grounds for using genetically engineered P. marinus as a new oral vaccine platform to induce systemic immunity against infectious agents. C1 [Wijayalath, Wathsala; Majji, Sai; Kleschenko, Yuliya; Villasante, Eileen Franke; Casares, Sofia] Naval Med Res Ctr, Walter Reed Army Inst Res, US Mil Malaria Vaccine Program, Silver Spring, MD 20910 USA. [Pow-Sang, Luis; Brumeanu, Teodor D.; Casares, Sofia] Uniformed Serv Univ Hlth Sci, Dept Med, Bethesda, MD 20814 USA. [Vasta, Gerardo R.; Fernandez-Robledo, Jose-Antonio] Univ Maryland, Sch Med, Dept Microbiol & Immunol, Baltimore, MD 21201 USA. RP Casares, S (reprint author), Naval Med Res Ctr, Walter Reed Army Inst Res, US Mil Malaria Vaccine Program, Silver Spring, MD 20910 USA. EM sofia.casares@med.navy.mil FU work unit number 6000.RAD1.F. under Military Infectious Diseases Research Program (MDRIP) [F0338_13_NM]; National Science Foundation (NSF) [IOS 1063729, IOS 1050518, IOS 0958016]; National Institutes of Health (NIH) [1R21AI076797-01A2] FX This work was supported by work unit number 6000.RAD1.F. under grants from the Military Infectious Diseases Research Program (MDRIP, #F0338_13_NM)to SC, National Science Foundation (NSF, #IOS 1063729, #IOS 1050518, #IOS 0958016) to GRV, and National Institutes of Health (NIH, #1R21AI076797-01A2) to JAFR. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. NR 69 TC 2 Z9 2 U1 1 U2 5 PU PUBLIC LIBRARY SCIENCE PI SAN FRANCISCO PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA SN 1932-6203 J9 PLOS ONE JI PLoS One PD JAN 31 PY 2014 VL 9 IS 1 AR e87435 DI 10.1371/journal.pone.0087435 PG 10 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA 302RF UT WOS:000330621900112 PM 24498105 ER PT J AU Jacobson, LC Ren, XM Molinero, V AF Jacobson, Liam C. Ren, Xiaoming Molinero, Valeria TI Assessing the Effects of Crowding, Pore Size, and Interactions on Electro-Osmotic Drag Coefficients SO JOURNAL OF PHYSICAL CHEMISTRY C LA English DT Article ID MOLECULAR-DYNAMICS SIMULATIONS; POLY(PERFLUOROSULFONIC ACID) MEMBRANES; PROTON-EXCHANGE MEMBRANES; FUEL-CELLS; POLYMER ELECTROLYTES; TRANSPORT-PROPERTIES; WATER TRANSPORT; IN-SITU; NAFION; ELCTROOSMOSIS AB Water flow coupled to the migration of ions is an important aspect of the performance of polymer electrolyte membrane fuel cells. The water gradients arising from the operation of fuel cells can result in flooding and drying-out of the electrodes and drying of regions of the membrane, with concomitant losses in conductivity and efficiency. The electro-osmotic drag coefficient measures the ratio between the flow of solvent molecules to that of a charged species toward an electrode in the presence of an applied electric field. The effects of variables such as pore radius, crowding, temperature, electric field strength, and ion concentration on the mobility of ions and accompanying water molecules in an applied electric field are still not well understood. Here, we investigate these factors with coarse-grained molecular simulations using an efficient model of water and sodium chloride ions and compare these results with those from previous experiments on proton exchange membranes as well as new experimental results for an anion exchange membrane. The anion exchange membranes have a smaller value of K-drag than the proton-exchange membranes, which may be attributed to smaller water domains and a different charge carrier (hydroxide instead of protons). We directly determine the role of pore size on K-drag and confirm that narrower pores result in less electro-osmotic drag. Our simulations show that K-drag is sensitive to the interaction of the charge carrier with water molecules. The results of this work suggest that the most promising approach to minimize electro-osmotic drag while maintaining adequate ion conductivity is to control the morphology of the membrane structure at the microscopic level. C1 [Jacobson, Liam C.; Molinero, Valeria] Univ Utah, Dept Chem, Salt Lake City, UT 84112 USA. [Ren, Xiaoming] US Army Res Lab, RDRL SED C, Adelphi, MD 20783 USA. RP Molinero, V (reprint author), Univ Utah, Dept Chem, 315 South 1400 East, Salt Lake City, UT 84112 USA. EM valeria.molinero@utah.edu FU Army Research Laboratory; Center for High Performance Computing at the University of Utah FX This research was sponsored by the Army Research Laboratory and was accomplished under Cooperative Agreement No. W911NF-12-2-0023. The views and conclusions contained in this document are those of the authors and should not be interpreted as representing the official policies, either expressed or implied, of the Army Research Laboratory or the U.S. Government. We thank the Center for High Performance Computing at the University of Utah for support and resources. NR 41 TC 4 Z9 4 U1 2 U2 28 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1932-7447 J9 J PHYS CHEM C JI J. Phys. Chem. C PD JAN 30 PY 2014 VL 118 IS 4 BP 2093 EP 2103 DI 10.1021/jp410910r PG 11 WC Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Chemistry; Science & Technology - Other Topics; Materials Science GA 302NC UT WOS:000330610200040 ER PT J AU Watters, EJ Sengupta, SK Peterson, GW Whitten, JE AF Watters, Evan J. Sengupta, Sandip K. Peterson, Gregory W. Whitten, James E. TI Photoluminescence of zirconium hydroxide: Origin of a chemisorption-induced 'red-stretch' SO CHEMICAL PHYSICS LETTERS LA English DT Article ID SULFUR-DIOXIDE; REMOVAL; SPECTRA; IONS; ZNO; OH AB Zirconium hydroxide particles are reactive and photoluminescent, emitting blue light under ultraviolet (UV) irradiation. Adsorption-induced changes in the photoluminescence (PL) offer opportunities for gas sensor/filtration applications. The PL of Zr(OH)(4) is quenched in the presence of molecular oxygen, likely through trapping of surface electrons via the formation of O-2(-). Heating the powder high enough to desorb hydroxyl groups broadens the PL spectrum toward longer wavelengths. This 'red-stretch' also occurs upon reaction with sulfur dioxide, which replaces terminal hydroxyl groups with sulfite ones. Excessive UV irradiation correspondingly induces this effect. A mechanism is proposed to account for the red-stretch. (C) 2013 Elsevier B.V. All rights reserved. C1 [Watters, Evan J.; Sengupta, Sandip K.; Whitten, James E.] Univ Massachusetts, Dept Chem, Lowell, MA 01854 USA. [Peterson, Gregory W.] US Army Edgewood Chem & Biol Ctr, Aberdeen Proving Ground, MD 21010 USA. RP Whitten, JE (reprint author), Univ Massachusetts, Dept Chem, Lowell, MA 01854 USA. EM James_Whitten@uml.edu FU Army Research Office; Defense Threat Reduction Agency [BA07PR0105] FX The authors acknowledge support from the Army Research Office. This work was conducted under Defense Threat Reduction Agency, Project No. BA07PR0105. NR 20 TC 1 Z9 1 U1 2 U2 19 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0009-2614 EI 1873-4448 J9 CHEM PHYS LETT JI Chem. Phys. Lett. PD JAN 30 PY 2014 VL 592 BP 297 EP 301 DI 10.1016/j.cplett.2013.12.035 PG 5 WC Chemistry, Physical; Physics, Atomic, Molecular & Chemical SC Chemistry; Physics GA 295IS UT WOS:000330110400057 ER PT J AU Yao, CW Alvarado, JL Marsh, CP Jones, BG Collins, MK AF Yao, Chun-Wei Alvarado, Jorge L. Marsh, Charles P. Jones, Barclay G. Collins, Michael K. TI Wetting behavior on hybrid surfaces with hydrophobic and hydrophilic properties SO APPLIED SURFACE SCIENCE LA English DT Article DE Hybrid surface; Hydrophobic; Hydrophilic; Water condensation ID SUPERHYDROPHOBIC SURFACES; WATER CONDENSATION; ULTRAHYDROPHOBIC SURFACES; GROWTH DYNAMICS; HEAT-TRANSFER AB Hybrid surfaces consisting of a micropillar array of hydrophobic and hydrophilic sites were designed and fabricated to understand the effects of their unique surface morphology and chemistry on droplet condensation. Droplet impingement experiments have revealed that hybrid surfaces exhibit high contact angles, which is characteristic of purely hydrophobic surfaces. However, little is known about the wetting behavior of droplets that nucleate and grow on hybrid surfaces during condensation. In fact, condensed droplets display a distinct wetting behavior during the droplet growth phase which cannot be reproduced by simply impinging droplets on hybrid surfaces. In this study, hybrid surfaces with three different spacing ratios were subjected to condensation tests using an environmental scanning electron microscopy (ESEM) and a condensation cell under ambient conditions. For hybrid surfaces with spacing ratio below 2, droplets were observed to form on top and sides of the micropillars, where they grew, coalesced with adjacent droplets, and shed after reaching a given size. After shedding, the top surface remained partially dry, which allowed for immediate droplet growth. For hybrid surfaces with spacing ratio equal to 2, a different wetting behavior was observed, where droplets basically coalesced and formed a thin liquid film which was ultimately driven into the valleys of the microstructure. The liquid shedding process led to the renucleation of droplets primarily on top of the dry hydrophilic sites. To better understand the nature of droplet wetting on hybrid surfaces, a surface energy-based model was developed to predict the transition between the two observed wetting behaviors at different spacing ratios. The experimental and analytical results indicate that micropillar spacing ratio is the key factor for promoting different wetting behavior of condensed droplets on hybrid surfaces. (C) 2013 Elsevier B.V. All rights reserved. C1 [Yao, Chun-Wei] Texas A&M Univ, Dept Mech Engn, College Stn, TX 77843 USA. [Alvarado, Jorge L.] Texas A&M Univ, Dept Engn Technol & Ind Distribut, College Stn, TX 77843 USA. [Marsh, Charles P.; Collins, Michael K.] ERDC Construct Engn Res Lab, Champaign, IL 61826 USA. [Marsh, Charles P.; Jones, Barclay G.; Collins, Michael K.] Univ Illinois, Dept Nucl Plasma & Radiol Engn, Urbana, IL 61801 USA. RP Alvarado, JL (reprint author), Texas A&M Univ, Dept Engn Technol & Ind Distribut, College Stn, TX 77843 USA. EM Alvarado@entc.tamu.edu RI Yao, Chun-Wei/K-4271-2016; OI Yao, Chun-Wei/0000-0002-9032-9592; Alvarado, Jorge/0000-0002-4059-6588 NR 30 TC 15 Z9 15 U1 10 U2 75 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0169-4332 EI 1873-5584 J9 APPL SURF SCI JI Appl. Surf. Sci. PD JAN 30 PY 2014 VL 290 BP 59 EP 65 DI 10.1016/j.apsusc.2013.10.188 PG 7 WC Chemistry, Physical; Materials Science, Coatings & Films; Physics, Applied; Physics, Condensed Matter SC Chemistry; Materials Science; Physics GA 280VY UT WOS:000329060100010 ER PT J AU Rokni, MR Widener, CA Champagne, VR AF Rokni, M. R. Widener, C. A. Champagne, V. R. TI Microstructural stability of ultrafine grained cold sprayed 6061 aluminum alloy SO APPLIED SURFACE SCIENCE LA English DT Article DE Aluminum alloys; Cold spraying; Non-isothermal; Annealing; TEM ID SEVERE PLASTIC-DEFORMATION; VACANCY FORMATION ENERGIES; SOLUTE SEGREGATION; AL-ZN; DISLOCATION LINE; HEATING RATE; MG ALLOYS; BOUNDARY; RECRYSTALLIZATION; DIFFRACTION AB The microstructural stability of ultrafine grained (UFG) cold spray 6061 aluminum deposits produced by high pressure cold spray were investigated by in situ heating to a fully annealed state via a hot-stage transmission electron microscope (TEM). It was possible to observe the precise locations and temperatures of different microstructural changes, like dislocation movement and other restoration processes. Even after heating up to the annealing temperature for this alloy, the deposited layer in the perpendicular direction was found to preserve the UFG structures, which were the result of different recrystallization mechanisms caused by the high strains present during cold spraying. Extensive solute segregation at the grain boundaries acted as an obstruction for grain boundary migration in this direction, thereby preventing grain growth. However, in the direction parallel to the deposited surface, the UFGs were not resistant to grain coursing like the other direction, since the grain boundaries had much less solute segregation. (C) 2013 Elsevier B.V. All rights reserved. C1 [Rokni, M. R.; Widener, C. A.] South Dakota Sch Mines & Technol, Adv Mat Proc Ctr, Dept Mat & Met Engn, Rapid City, SD 57701 USA. [Champagne, V. R.] US Army Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD USA. RP Rokni, MR (reprint author), South Dakota Sch Mines & Technol, Adv Mat Proc Ctr, Dept Mat & Met Engn, Rapid City, SD 57701 USA. EM mohammadreza.rokni@mines.sdsmt.edu OI Widener, Christian/0000-0002-4303-3246 NR 39 TC 9 Z9 9 U1 0 U2 28 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0169-4332 EI 1873-5584 J9 APPL SURF SCI JI Appl. Surf. Sci. PD JAN 30 PY 2014 VL 290 BP 482 EP 489 DI 10.1016/j.apsusc.2013.11.127 PG 8 WC Chemistry, Physical; Materials Science, Coatings & Films; Physics, Applied; Physics, Condensed Matter SC Chemistry; Materials Science; Physics GA 280VY UT WOS:000329060100070 ER PT J AU Zhu, H Roe, JL Park, KH Tan, T Lin, PH Ma, JJ Walters, TJ AF Zhu, Hua Roe, Janet L. Park, Ki Ho Tan, Tao Lin, Pei-hui Ma, Jianjie Walters, Thomas J. TI Amelioration of Ischemia-Reperfusion Induced Muscle Injury by the Recombinant Human MG53 Protein SO BIOPHYSICAL JOURNAL LA English DT Meeting Abstract CT 58th Annual Meeting of the Biophysical-Society CY FEB 15-19, 2014 CL San Francisco, CA SP Biophys Soc C1 [Zhu, Hua; Park, Ki Ho; Tan, Tao; Lin, Pei-hui; Ma, Jianjie] Ohio State Univ, Dept Surg, Davis Heart & Lung Res Inst, Columbus, OH 43210 USA. [Roe, Janet L.; Walters, Thomas J.] US Army Inst Surg Res, Ft Sam Houston, TX USA. RI Zhu, Hua/G-4409-2010 NR 0 TC 0 Z9 0 U1 0 U2 4 PU CELL PRESS PI CAMBRIDGE PA 600 TECHNOLOGY SQUARE, 5TH FLOOR, CAMBRIDGE, MA 02139 USA SN 0006-3495 EI 1542-0086 J9 BIOPHYS J JI Biophys. J. PD JAN 28 PY 2014 VL 106 IS 2 SU 1 BP 728A EP 729A PG 2 WC Biophysics SC Biophysics GA AI6QE UT WOS:000337000404142 ER PT J AU Sun, WB Videen, G Mishchenko, MI AF Sun, Wenbo Videen, Gorden Mishchenko, Michael I. TI Detecting super- thin clouds with polarized sunlight SO GEOPHYSICAL RESEARCH LETTERS LA English DT Article DE Reflected light; angle of linear polarization; detection of clouds ID PART II; CIRRUS; TEMPERATURE; AEROSOLS; MISSION; SPACE; MODIS AB We report a novel method for detecting cloud particles in the atmosphere. Solar radiation backscattered from clouds is studied with both satellite data and a radiative transfer model. A distinct feature is found in the angle of linear polarization of solar radiation that is backscattered from clouds. The dominant backscattered electric field from the clear-sky Earth-atmosphere system is nearly parallel to the Earth surface. However, when clouds are present, this electric field can rotate significantly away from the parallel direction. Model results demonstrate that this polarization feature can be used to detect super-thin cirrus clouds having an optical depth of only similar to 0.06 and super-thin liquid water clouds having an optical depth of only similar to 0.01. Such clouds are too thin to be sensed using any current passive satellite instruments. C1 [Sun, Wenbo] Sci Syst & Applicat Inc, Hampton, VA 23666 USA. [Sun, Wenbo] NASA, Langley Res Ctr, Hampton, VA 23665 USA. [Videen, Gorden] Space Sci Inst, Boulder, CO USA. [Videen, Gorden] Army Res Lab, Adelphi, MD USA. [Mishchenko, Michael I.] NASA, Goddard Inst Space Studies, New York, NY 10025 USA. RP Sun, WB (reprint author), Sci Syst & Applicat Inc, Hampton, VA 23666 USA. EM wenbo.sun-1@nasa.gov RI Mishchenko, Michael/D-4426-2012; Richards, Amber/K-8203-2015 FU NASA Glory fund [09-GLORY09-0027]; NASA CLARREO mission FX This work was supported by NASA Glory fund 09-GLORY09-0027. Wenbo Sun was also supported by NASA CLARREO mission. The authors thank Hal B. Maring, Bruce A. Wielicki, Rosemary R. Baize, and David F. Young for these supports and thank Constantine Lukashin for preparing the PARASOL data. NR 22 TC 9 Z9 9 U1 0 U2 7 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA SN 0094-8276 EI 1944-8007 J9 GEOPHYS RES LETT JI Geophys. Res. Lett. PD JAN 28 PY 2014 VL 41 IS 2 BP 688 EP 693 DI 10.1002/2013GL058840 PG 6 WC Geosciences, Multidisciplinary SC Geology GA AD1JT UT WOS:000332991000070 ER PT J AU Crawford, KW Njeru, D Maswai, J Omondi, M Apollo, D Kimetto, J Gitonga, L Munyao, J Langat, R Aoko, A Tarus, J Khamadi, S Hamm, TE AF Crawford, Keith W. Njeru, Dorothy Maswai, Jonah Omondi, Milton Apollo, Duncan Kimetto, Jane Gitonga, Lawrence Munyao, James Langat, Raphael Aoko, Appolonia Tarus, Jemutai Khamadi, Samoel Hamm, Tiffany E. TI Occurrence of etravirine/rilpivirine-specific resistance mutations selected by efavirenz and nevirapine in Kenyan patients with non-B HIV-1 subtypes failing antiretroviral therapy SO AIDS LA English DT Article ID HUMAN-IMMUNODEFICIENCY-VIRUS; DRUG-RESISTANCE; INTERPRETATION ALGORITHMS; PERINATAL TRANSMISSION; REVERSE-TRANSCRIPTASE; GENOTYPIC RESISTANCE; TYPE-1; PROTEASE; INHIBITORS; DIVERSITY AB Resistance to efavirenz and nevirapine has not been associated with mutations at position 138 of reverse transcriptase. In an evaluation of virologic suppression rates in PEPFAR (President's Emergency Plan For AIDS Relief) clinics in Kenya among patients on first-line therapy (RV288), 63% (617/975) of randomly selected patients on antiretroviral therapy were suppressed (HIV RNA<400copies/ml). Among those with non-nucleoside reverse transcriptase inhibitor resistance (n=101), 14 (13.8%) had substitutions at 138 (A, G, K or Q), mutations selected only by etravirine and rilpivirine in subtype B viruses. All 14 patients received efavirenz or nevirapine, not etravirine or rilpivirine, and were predominantly subtype A1. This may be the first report of efavirenz and nevirapine selecting these mutations in these subtypes. C1 [Crawford, Keith W.; Hamm, Tiffany E.] Walter Reed Army Inst Res, US Mil HIV Res Program, Global Hlth Programs, Silver Spring, MD USA. [Crawford, Keith W.; Hamm, Tiffany E.] Henry M Jackson Fdn Adv Mil Med, Bethesda, MD USA. [Njeru, Dorothy; Apollo, Duncan; Gitonga, Lawrence] USAM RU K, KDF, Nairobi, Kenya. [Maswai, Jonah; Omondi, Milton; Kimetto, Jane; Munyao, James; Langat, Raphael; Aoko, Appolonia; Tarus, Jemutai] USAMRU K, Kenya Med Res Inst KEMRI, Walter Reed Program, SRV, Kerich, Kenya. [Khamadi, Samoel] Southern Highlands Walter Reed Program, Mbeya, Tanzania. RP Crawford, KW (reprint author), Walter Reed Army Inst Res, US Mil HIV Res Program, Bethesda, MD 20814 USA. FU President's Emergency Plan for AIDS Relief (PEPFAR) through the US Department of Defense [W81XWH-11-2-0174]; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. FX This research has been supported by the President's Emergency Plan for AIDS Relief (PEPFAR) through the US Department of Defense under the terms of cooperative agreement W81XWH-11-2-0174 with the Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. The views expressed are those of the authors and should not be construed to represent the positions of the US Army or DoD. NR 24 TC 6 Z9 6 U1 0 U2 0 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0269-9370 EI 1473-5571 J9 AIDS JI Aids PD JAN 28 PY 2014 VL 28 IS 3 BP 442 EP 445 DI 10.1097/QAD.0000000000000140 PG 4 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA AB1OA UT WOS:000331560500018 PM 24670527 ER PT J AU Zhelev, DV Zheleva, TS AF Zhelev, Doncho V. Zheleva, Tsvetanka S. TI Silver nanoplates with ground or metastable structures obtained from template-free two-phase aqueous/organic synthesis SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID ELECTRON-DIFFRACTION PATTERNS; HEXAGONAL STRUCTURE; CRYSTAL-STRUCTURE; NANOSTRUCTURES; NANOWIRES; GROWTH; AG; NANOCRYSTALS; PROGRAM; GOLD AB Silver has unique electrical, catalytic, and plasmonic characteristics and has been widely sought for fabrication of nanostructures. The properties of silver nanostructures are intimately coupled to the structure of silver crystals. Two crystal structures are known for silver: the stable (ground) state cubic face centered 3C-Ag structure and the metastable hexagonal 4H-Ag structure. Recently, Chackraborty et al. [J. Phys.: Condens. Matter 23, 325401 (2011)] discovered a low density, highly reactive metastable hexagonal 2H-Ag structure accessible during electrodeposition of silver nanowires in porous anodic alumina templates. This 2H-Ag structure has enhanced electrical and catalytic characteristics. In the present work we report template-free synthesis of silver nanoplates with the metastable 2H-Ag crystal structure, which appears together with the ground 3C-Ag and the metastable 4H-Ag structures in a two-phase solution synthesis with citric acid as the capping agent. The capacity of citric acid to stabilize both the stable and the metastable structures is explained by its preferential binding to the close packed facets of Ag crystals, which are the (111) planes for 3C-Ag and the (0001) planes for 4H-Ag and 2H-Ag. Nanoplate morphology and structure are characterized using scanning electron microscopy, X-ray diffraction, and transmission electron microscopy. The synthesized nanoplates have thickness from 15 to 17 nm and edge length from 1 to 10 mu m. Transmission electron microscopy selected area electron diffraction is used to uniquely identify and distinguish between nanoplates with 2H-Ag or 4H-Ag or 3C-Ag structures. C1 [Zhelev, Doncho V.; Zheleva, Tsvetanka S.] Army Res Lab, Adelphi, MD 20783 USA. RP Zhelev, DV (reprint author), NCI, Canc & Inflammat Program, Ctr Canc Res, Frederick, MD 21702 USA. EM dontcho.jelev@nih.gov FU Army Research Laboratory FX D.V.Z. acknowledges the financial support from the Army Research Laboratory. D.V.Z. is grateful to Dr. Paul Pellegrino for the introduction to surface enhanced Raman spectroscopy. NR 42 TC 2 Z9 2 U1 2 U2 36 PU AMER INST PHYSICS PI MELVILLE PA 1305 WALT WHITMAN RD, STE 300, MELVILLE, NY 11747-4501 USA SN 0021-8979 EI 1089-7550 J9 J APPL PHYS JI J. Appl. Phys. PD JAN 28 PY 2014 VL 115 IS 4 AR 044309 DI 10.1063/1.4859497 PG 7 WC Physics, Applied SC Physics GA AA6LW UT WOS:000331210800101 ER PT J AU Chittigori, J Kumar, A Li, L Thota, S Kokil, A Samuelson, LA Sandman, DJ Kumar, J AF Chittigori, Joshna Kumar, Abhishek Li, Lian Thota, Sammaiah Kokil, Akshay Samuelson, Lynne A. Sandman, Daniel J. Kumar, Jayant TI Synthesis of a self organizable curcumin derivative and investigation of its interaction with metals in 100% aqueous media SO TETRAHEDRON LA English DT Article DE Synthesis; Curcumin; Bis PEGylated curcumin; Self organization; Nanoparticles; Absorption and fluorescence; Metal interactions ID ALZHEIMERS-DISEASE; FLUORESCENT CHEMOSENSOR; PEGYLATED CURCUMIN; PANCREATIC-CANCER; ALUMINUM IONS; COPPER; COMPLEX; AGGREGATION; CHEMISTRY; EVIDENCES AB We report the synthesis of a self organizable and water dispersible bis PEGylated (bis polyethyleneglycolated) curcumin (1) using an efficient synthetic method. Compound 1 forms nanoparticles on the order of 90 nm in water. Even though it forms nanoparticles, compound 1 interacts strongly with metal ions, Al+3, Cu+2, and Hg+2. Fluorescence and absorption spectroscopic techniques were employed to investigate the metal interactions of these nanoparticles. Al+3 and Cu+2 ions interact with compound 1 leading to enhancement and dramatic quenching in the fluorescence of the latter in 100% water, respectively. Addition of Hg+2 ions to compound 1 in water produces a ratiometric change in the absorption spectra of the nanoparticles. Although PEGylated curcumin derivatives were reported in the past, there have been no reports on their self organization into nanoparticles and extensive studies on their metal interaction properties in 100% water using its fluorescence and absorption properties. (C) 2013 Elsevier Ltd. All rights reserved. C1 [Chittigori, Joshna; Kumar, Abhishek; Thota, Sammaiah; Kokil, Akshay; Sandman, Daniel J.; Kumar, Jayant] Univ Massachusetts Lowell, Ctr Adv Mat, Lowell, MA 01854 USA. [Chittigori, Joshna; Sandman, Daniel J.] Univ Massachusetts Lowell, Dept Chem, Lowell, MA 01854 USA. [Kumar, Abhishek; Kumar, Jayant] Univ Massachusetts Lowell, Dept Phys, Lowell, MA 01854 USA. [Li, Lian; Samuelson, Lynne A.] US Army Natick Soldier Res, Ctr Dev & Engn, Natick, MA 01760 USA. RP Sandman, DJ (reprint author), Univ Massachusetts Lowell, Ctr Adv Mat, Lowell, MA 01854 USA. EM Jayant_Kumar@uml.edu RI Kokil, Akshay/A-6886-2009 OI Kokil, Akshay/0000-0002-8295-2878 FU US Department of Energy [DE-SC0001087]; Faculty Research Participation Program at the US Army Natick Soldier Research, Development and Engineering Center (NSRDEC) FX Financial support from the US Department of Energy (Award Number DE-SC0001087) is gratefully acknowledged. This research was also supported in part by an appointment to the Faculty Research Participation Program at the US Army Natick Soldier Research, Development and Engineering Center (NSRDEC) administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the US Department of Energy and NSRDEC. We also thank Mr. Santeufemio (UMASS Lowell) for the cryo SEM, Tyler Carter (UMASS Lowell) for mass spectroscopic characterization and Soujanya Muralidhara for zeta potential measurements. NR 44 TC 5 Z9 6 U1 2 U2 25 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0040-4020 J9 TETRAHEDRON JI Tetrahedron PD JAN 28 PY 2014 VL 70 IS 4 BP 991 EP 995 DI 10.1016/j.tet.2013.11.071 PG 5 WC Chemistry, Organic SC Chemistry GA 295VG UT WOS:000330143800030 ER PT J AU Caras, RJ Sterbis, JR AF Caras, R. J. Sterbis, Joseph R. TI Prostate Cancer Nomograms: A Review of Their Use in Cancer Detection and Treatment SO CURRENT UROLOGY REPORTS LA English DT Article DE Prostate cancer; Nomogram; Treatment counseling; PSA; Prostate biopsy ID LYMPH-NODE DISSECTION; DIGITAL RECTAL EXAMINATION; RADICAL PROSTATECTOMY; PREOPERATIVE NOMOGRAM; EXTRACAPSULAR EXTENSION; COMPARATIVE VALIDATION; INTERNAL VALIDATION; EXTERNAL VALIDATION; ACTIVE SURVEILLANCE; PREDICTION AB As prostate cancer treatment discussions have grown more complex, increasing numbers of nomograms to guide decision-making have been found in the literature. Such nomograms can influence every step in the prostate cancer therapeutic process, from determining the need for biopsy to the need for adjuvant therapy. With a properly counseled patient who is aware of the limitations of nomograms, such tools assist in the shared decision-making that characterizes modern informed consent. C1 [Caras, R. J.; Sterbis, Joseph R.] Tripler Army Med Ctr, Honolulu, HI 96859 USA. RP Sterbis, JR (reprint author), Tripler Army Med Ctr, 1 Jarrett White Rd, Honolulu, HI 96859 USA. EM ronald.j.caras.mil@mail.mil; joseph.r.sterbis.mil@mail.mil NR 54 TC 6 Z9 6 U1 0 U2 5 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1527-2737 J9 CURR UROL REP JI Curr. Urol. Rep. PD JAN 23 PY 2014 VL 15 IS 3 AR 391 DI 10.1007/s11934-013-0391-0 PG 6 WC Urology & Nephrology SC Urology & Nephrology GA AJ7UG UT WOS:000337903100001 PM 24452739 ER PT J AU Notari, L Riera, DC Sun, R Bohl, JA McLean, LP Madden, KB van Rooijen, N Vanuytsel, T Urban, JF Zhao, AP Shea-Donohue, T AF Notari, Luigi Riera, Diana C. Sun, Rex Bohl, Jennifer A. McLean, Leon P. Madden, Kathleen B. van Rooijen, Nico Vanuytsel, Tim Urban, Joseph F., Jr. Zhao, Aiping Shea-Donohue, Terez TI Role of Macrophages in the Altered Epithelial Function during a Type 2 Immune Response Induced by Enteric Nematode Infection SO PLOS ONE LA English DT Article ID ALTERNATIVELY ACTIVATED MACROPHAGES; BRUSH-BORDER MEMBRANE; RAT SMALL-INTESTINE; HELIGMOSOMOIDES-POLYGYRUS INFECTION; INDUCIBLE FACTOR-I; GLUCOSE-METABOLISM; INSULIN-RESISTANCE; SUGAR ABSORPTION; TASTE RECEPTORS; INNATE IMMUNITY AB Parasitic enteric nematodes induce a type 2 immune response characterized by increased production of Th2 cytokines, IL-4 and IL-13, and recruitment of alternatively activated macrophages ( M2) to the site of infection. Nematode infection is associated with changes in epithelial permeability and inhibition of sodium-linked glucose absorption, but the role of M2 in these effects is unknown. Clodronate-containing liposomes were administered prior to and during nematode infection to deplete macrophages and prevent the development of M2 in response to infection with Nippostrongylus brasiliensis. The inhibition of epithelial glucose absorption that is associated with nematode infection involved a macrophage-dependent reduction in SGLT1 activity, with no change in receptor expression, and a macrophage-independent down-regulation of GLUT2 expression. The reduced transport of glucose into the enterocyte is compensated partially by an up-regulation of the constitutive GLUT1 transporter consistent with stress-induced activation of HIF-1 alpha. Thus, nematode infection results in a "lean" epithelial phenotype that features decreased SGLT1 activity, decreased expression of GLUT2 and an emergent dependence on GLUT1 for glucose uptake into the enterocyte. Macrophages do not play a role in enteric nematode infection-induced changes in epithelial barrier function. There is a greater contribution, however, of paracellular absorption of glucose to supply the energy demands of host resistance. These data provide further evidence of the ability of macrophages to alter glucose metabolism of neighboring cells. C1 [Notari, Luigi; Sun, Rex; Bohl, Jennifer A.; McLean, Leon P.; Zhao, Aiping; Shea-Donohue, Terez] Univ Maryland, Sch Med, Dept Med, Baltimore, MD 21201 USA. [Notari, Luigi; Sun, Rex; Bohl, Jennifer A.; McLean, Leon P.; Zhao, Aiping; Shea-Donohue, Terez] Univ Maryland, Sch Med, Mucosal Biol Res Ctr, Baltimore, MD 21201 USA. [Riera, Diana C.] Walter Reed Army Med Ctr, Dept Pediat, Washington, DC 20307 USA. [Riera, Diana C.; Madden, Kathleen B.] Uniformed Serv Univ Hlth Sci, Dept Pediat, Bethesda, MD 20814 USA. [van Rooijen, Nico] Vrije Univ Amsterdam, VUMC, Dept Mol Cell Biol, Amsterdam, Netherlands. [Vanuytsel, Tim] Katholieke Univ Leuven, Univ Hosp Gasthuisberg, Translat Res Ctr Gastrointestinal Disorders, Louvain, Belgium. [Urban, Joseph F., Jr.] ARS, USDA, Beltsville Human Nutr Res Ctr, Diet Genom & Immunol Lab, Beltsville, MD USA. RP Shea-Donohue, T (reprint author), Univ Maryland, Sch Med, Dept Med, Baltimore, MD 21201 USA. EM tdonohue@mbrc.maryland.edu OI Urban, Joseph/0000-0002-1590-8869 FU National Institutes of Health [R01-AI/DK49316, DK083418, T32 DK-067872]; U.S. Department of Agriculture CRIS Project [1235-52000-053]; Flanders research foundation (FWO, Fonds Wetenschappelijk Onderzoek) FX This work was supported by National Institutes of Health Grants R01-AI/DK49316 (to T.S.-D.), DK083418 (to A.Z.), T32 DK-067872 (to L. P. M., J.A.B., and R. S.), by U.S. Department of Agriculture CRIS Project 1235-52000-053 (to J.F.U.) and by a grant from the Flanders research foundation (FWO, Fonds Wetenschappelijk Onderzoek) (to T. V.). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. NR 66 TC 7 Z9 7 U1 2 U2 8 PU PUBLIC LIBRARY SCIENCE PI SAN FRANCISCO PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA SN 1932-6203 J9 PLOS ONE JI PLoS One PD JAN 23 PY 2014 VL 9 IS 1 AR e84763 DI 10.1371/journal.pone.0084763 PG 11 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA 297XI UT WOS:000330288000006 PM 24465430 ER PT J AU Savescu, M Johnson, S Kara, AH Crutcher, SH Kohl, R Biswas, A AF Savescu, Michelle Johnson, Stephen Kara, Abdul H. Crutcher, Sihon H. Kohl, Russell Biswas, Anjan TI Conservation laws for optical solitons with spatio-temporal dispersion SO JOURNAL OF ELECTROMAGNETIC WAVES AND APPLICATIONS LA English DT Article DE birefringence; integrability; solitons ID NONLINEAR SCHRODINGERS EQUATION; PERTURBATION AB The conservation laws for optical solitons with spatio-temporal dispersion are obtained in this paper. There are three conserved quantities that are reported in this paper. They are the power, linear momentum, and the Hamiltonian. The conserved quantities, from their respective densities, are obtained from 1-soliton solution that was reported earlier. Five types of nonlinear media are taken into account. C1 [Savescu, Michelle; Johnson, Stephen; Biswas, Anjan] Delaware State Univ, Dept Math Sci, Dover, DE 19901 USA. [Savescu, Michelle] Kuztown Univ Penn, Dept Math, Kutztown, PA 19530 USA. [Johnson, Stephen] Lake Forest High Sch, Felton, DE 19943 USA. [Kara, Abdul H.] Univ Witwatersrand, Sch Math, Ctr Differential Equat Continuum Mech & Applicat, ZA-2050 Johannesburg, South Africa. [Crutcher, Sihon H.] US Army Res Dev & Engn Command, Redstone Arsenal, AL 35898 USA. [Kohl, Russell] Univ Maryland Eastern Shore, Dept Math & Comp Sci, Princess Anne, MD 21853 USA. [Biswas, Anjan] King Abdulaziz Univ, Dept Math, Fac Sci, Jeddah 21589, Saudi Arabia. RP Biswas, A (reprint author), Delaware State Univ, Dept Math Sci, Dover, DE 19901 USA. EM biswas.anjan@gmail.com RI Biswas, Anjan /D-8500-2012 NR 15 TC 13 Z9 13 U1 1 U2 3 PU TAYLOR & FRANCIS LTD PI ABINGDON PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND SN 0920-5071 EI 1569-3937 J9 J ELECTROMAGNET WAVE JI J. Electromagn. Waves Appl. PD JAN 22 PY 2014 VL 28 IS 2 BP 242 EP 252 DI 10.1080/09205071.2013.863716 PG 11 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA 263VI UT WOS:000327835700010 ER PT J AU Tschopp, MA Gao, F Yang, L Solanki, KN AF Tschopp, M. A. Gao, F. Yang, L. Solanki, K. N. TI Binding energetics of substitutional and interstitial helium and di-helium defects with grain boundary structure in alpha-Fe SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID MONTE-CARLO SIMULATIONS; HE-VACANCY CLUSTERS; BCC IRON; MOLECULAR-DYNAMICS; DISPLACEMENT CASCADES; TENSILE-STRENGTH; ENERGY; FUSION; COPPER; IRRADIATION AB The formation/binding energetics and length scales associated with the interaction between He atoms and grain boundaries in BCC alpha-Fe were explored. Ten different low R grain boundaries from the < 100 > and < 110 > symmetric tilt grain boundary systems were used. In this work, we then calculated formation/binding energies for 1-2 He atoms in the substitutional and interstitial sites (HeV, He2V, HeInt, He(2)Int) at all potential grain boundary sites within 15 angstrom of the boundary (52 826 simulations total). The present results provide detailed information about the interaction energies and length scales of 1-2 He atoms with grain boundaries for the structures examined. A number of interesting new findings emerge from the present study. For instance, the Sigma 3(112) twin boundary in BCC Fe possesses a much smaller binding energy than other boundaries, which corresponds in long time dynamics simulations to the ability of an interstitial He defect to break away from the boundary in simulations on the order of nanoseconds. Additionally, positive correlations between the calculated formation/binding energies of the He defects (R>0.9) asserts that the local environment surrounding each site strongly influences the He defect energies and that highly accurate quantum mechanics calculations of lower order defects may be an adequate predictor of higher order defects. Various metrics to quantify or classify the local environment were compared with the He defect binding energies. The present work shows that the binding and formation energies for He defects are important for understanding the physics of He diffusion and trapping by grain boundaries, which can be important for modeling He interactions in polycrystalline steels. (C) 2014 AIP Publishing LLC. C1 [Tschopp, M. A.] US Army Res Lab, Dynam Res Corp, Aberdeen Proving Ground, MD 21005 USA. [Tschopp, M. A.] Mississippi State Univ, Ctr Adv Vehicular Syst, Starkville, MS 39762 USA. [Gao, F.; Yang, L.] Pacific NW Natl Lab, Richland, WA 99352 USA. [Solanki, K. N.] Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA. RP Tschopp, MA (reprint author), US Army Res Lab, Dynam Res Corp, Aberdeen Proving Ground, MD 21005 USA. EM mark.tschopp@gatech.edu RI Solanki, Kiran/E-8337-2010; Tschopp, Mark/B-1594-2008 OI Tschopp, Mark/0000-0001-8471-5035 FU U.S. Department of Energy, Office of Fusion Energy Science [DE-AC06-76RLO 1830]; Alternate Sponsored Fellowship (ASF) at PNNL FX F. G. and L. Y. are grateful for the support by the U.S. Department of Energy, Office of Fusion Energy Science, under Contract No. DE-AC06-76RLO 1830. The authors would like to acknowledge the support and discussions with Xin Sun and Moe Khaleel at Pacific Northwest National Laboratory. The authors would also like to acknowledge G. Henkelman for aiding in implementing the long time dynamics algorithm into the molecular dynamics code utilized within. Last, the authors would like to acknowledge Joanna Sun, high school student supported by Alternate Sponsored Fellowship (ASF) at PNNL, for her contributions to this work. NR 83 TC 10 Z9 11 U1 6 U2 36 PU AMER INST PHYSICS PI MELVILLE PA 1305 WALT WHITMAN RD, STE 300, MELVILLE, NY 11747-4501 USA SN 0021-8979 EI 1089-7550 J9 J APPL PHYS JI J. Appl. Phys. PD JAN 21 PY 2014 VL 115 IS 3 AR 033503 DI 10.1063/1.4861719 PG 16 WC Physics, Applied SC Physics GA 302OV UT WOS:000330615500020 ER PT J AU Sholukh, AM Byrareddy, SN Shanmuganathan, V Hemashettar, G Lakhashe, SK Rasmussen, RA Watkins, JD Vyas, HK Thorat, S Brandstoetter, T Mukhtar, MM Yoon, JK Novembre, FJ Villinger, F Landucci, G Forthal, DN Ratcliffe, S Tuero, I Robert-Guroff, M Polonis, VR Bilska, M Montefiori, DC Johnson, WE Ertl, HC Ruprecht, RM AF Sholukh, Anton M. Byrareddy, Siddappa N. Shanmuganathan, Vivekanandan Hemashettar, Girish Lakhashe, Samir K. Rasmussen, Robert A. Watkins, Jennifer D. Vyas, Hemant K. Thorat, Swati Brandstoetter, Tania Mukhtar, Muhammad M. Yoon, John K. Novembre, Francis J. Villinger, Francois Landucci, Gary Forthal, Donald N. Ratcliffe, Sarah Tuero, Iskra Robert-Guroff, Marjorie Polonis, Victoria R. Bilska, Miroslawa Montefiori, David C. Johnson, Welkin E. Ertl, Hildegund C. Ruprecht, Ruth M. TI Passive immunization of macaques with polyclonal anti-SHIV IgG against a heterologous tier 2 SHIV: outcome depends on IgG dose SO RETROVIROLOGY LA English DT Article DE Macaque model; Heterologous R5 SHIV clade C challenge; SHIVIG; Passive immunization; Enhancement of infection; Non-human primate model ID HIV-1/SIV CHIMERIC VIRUS; CLADE-C INFECTION; NEUTRALIZING ANTIBODIES; HIV-INFECTION; RHESUS MACAQUES; NONNEUTRALIZING ANTIBODIES; REPLICATION-COMPETENT; ENVELOPE GLYCOPROTEIN; MEDIATED ENHANCEMENT; VACCINE DEVELOPMENT AB Background: A key goal for HIV-1 envelope immunogen design is the induction of cross-reactive neutralizing antibodies (nAbs). As AIDS vaccine recipients will not be exposed to strains exactly matching any immunogens due to multiple HIV-1 quasispecies circulating in the human population worldwide, heterologous SHIV challenges are essential for realistic vaccine efficacy testing in primates. We assessed whether polyclonal IgG, isolated from rhesus monkeys (RMs) with high-titer nAbs (termed SHIVIG), could protect RMs against the R5-tropic tier-2 SHIV-2873Nip, which was heterologous to the viruses or HIV-1 envelopes that had elicited SHIVIG. Results: SHIVIG demonstrated binding to HIV Gag, Tat, and Env of different clades and competed with the broadly neutralizing antibodies b12, VRC01, 4E10, and 17b. SHIVIG neutralized tier 1 and tier 2 viruses, including SHIV-2873Nip. NK-cell depletion decreased the neutralizing activity of SHIVIG 20-fold in PBMC assays. Although SHIVIG neutralized SHIV-2873Nip in vitro, this polyclonal IgG preparation failed to prevent acquisition after repeated intrarectal low-dose virus challenges, but at a dose of 400 mg/kg, it significantly lowered peak viremia (P = 0.001). Unexpectedly, single-genome analysis revealed a higher number of transmitted variants at the low dose of 25 mg/kg, implying increased acquisition at low SHIVIG levels. In vitro, SHIVIG demonstrated complement-mediated Ab-dependent enhancement of infection (C'-ADE) at concentrations similar to those observed in plasmas of RMs treated with 25 mg/kg of SHIVIG. Conclusion: Our primate model data suggest a dual role for polyclonal anti-HIV-1 Abs depending on plasma levels upon virus encounter. C1 [Sholukh, Anton M.; Lakhashe, Samir K.; Vyas, Hemant K.; Mukhtar, Muhammad M.; Ruprecht, Ruth M.] Texas Biomed Res Inst, Dept Virol & Immunol, San Antonio, TX 78245 USA. [Sholukh, Anton M.; Byrareddy, Siddappa N.; Shanmuganathan, Vivekanandan; Hemashettar, Girish; Lakhashe, Samir K.; Rasmussen, Robert A.; Watkins, Jennifer D.; Vyas, Hemant K.; Thorat, Swati; Brandstoetter, Tania; Mukhtar, Muhammad M.; Yoon, John K.; Ruprecht, Ruth M.] Dana Farber Canc Inst, Boston, MA 02115 USA. [Sholukh, Anton M.; Byrareddy, Siddappa N.; Lakhashe, Samir K.; Rasmussen, Robert A.; Watkins, Jennifer D.; Vyas, Hemant K.; Thorat, Swati; Mukhtar, Muhammad M.; Ruprecht, Ruth M.] Harvard Univ, Sch Med, Boston, MA USA. [Novembre, Francis J.; Villinger, Francois] Emory Univ, Yerkes Natl Primate Res Ctr, Atlanta, GA 30322 USA. [Novembre, Francis J.] Emory Univ, Dept Microbiol & Immunol, Atlanta, GA 30322 USA. [Byrareddy, Siddappa N.; Villinger, Francois] Emory Univ, Dept Pathol & Lab Med, Atlanta, GA 30322 USA. [Landucci, Gary; Forthal, Donald N.] Univ Calif Irvine, Sch Med, Dept Med, Div Infect Dis, Irvine, CA 92717 USA. [Ratcliffe, Sarah] Univ Penn, Dept Biostat & Epidemiol, Perelman Sch Med, Philadelphia, PA 19104 USA. [Tuero, Iskra; Robert-Guroff, Marjorie] NCI, Ctr Canc Res, Vaccine Branch, Bethesda, MD 20892 USA. [Polonis, Victoria R.] Walter Reed Army Inst Res, Mil HIV Res Program, Silver Spring, MD USA. [Bilska, Miroslawa; Montefiori, David C.] Duke Univ, Sch Med, Dept Surg, Durham, NC USA. [Johnson, Welkin E.] Boston Coll, Dept Biol, Boston, MA USA. [Ertl, Hildegund C.] Wistar Inst Anat & Biol, Philadelphia, PA 19104 USA. RP Ruprecht, RM (reprint author), Texas Biomed Res Inst, Dept Virol & Immunol, POB 760549, San Antonio, TX 78245 USA. EM rruprecht@txbiomed.org RI Lakhashe, Samir/F-1150-2014; OI Byrareddy, Siddappa /0000-0002-7423-1763; Ratcliffe, Sarah/0000-0002-6644-8284 FU NIH [P01 AI082282, R37 AI034266, R01 DE023049, P01 AI048240, R01 AI083118, HHSN27201100016C]; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. [W81XWH-07-2-0067]; U.S. Department of Defense (DOD) [W81XWH-07-2-0067]; Intramural Research Program of the NIH, National Cancer Institute; Office of Research Infrastructure Programs/OD [P51OD11107] FX We thank Dr. J. Mascola for providing mAb VRC01, Dr. S.-L. Hu for providing SHIV-1157ip Env proteins, Dr. W. Marasco for providing mAb Fm-6, Dr. C. Ochsenbauer for providing pNL-LucR.T2A plasmid, P. Ehrenberg for production of the infectious molecular clones (GS 014 and GS 020), Dr. J. Hoxie for providing SupT1.R5 cells, and Juan Esquivel for technical help with the manuscript. This work was supported by NIH grants P01 AI082282 to RMR, SR and HCE, R37 AI034266, R01 DE023049 and P01 AI048240 to RMR, R01 AI083118 to WEJ, and HHSN27201100016C to DCM as well as by a cooperative agreement (W81XWH-07-2-0067) between the Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., and the U.S. Department of Defense (DOD) to VRP. This project was also funded in part by the Intramural Research Program of the NIH, National Cancer Institute, to MR-G and by the Office of Research Infrastructure Programs/OD P51OD11107 to the YNPRC. The authors have no conflicting financial interests. NR 46 TC 8 Z9 8 U1 0 U2 4 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1742-4690 J9 RETROVIROLOGY JI Retrovirology PD JAN 20 PY 2014 VL 11 AR 8 DI 10.1186/1742-4690-11-8 PG 15 WC Virology SC Virology GA AB3OT UT WOS:000331700800001 PM 24444350 ER PT J AU Narayanan, A Amaya, M Voss, K Chung, M Benedict, A Sampey, G Kehn-Hall, K Luchini, A Liotta, L Bailey, C Kumar, A Bavari, S Hakami, RM Kashanchi, F AF Narayanan, Aarthi Amaya, Moushimi Voss, Kelsey Chung, Myung Benedict, Ashwini Sampey, Gavin Kehn-Hall, Kylene Luchini, Alessandra Liotta, Lance Bailey, Charles Kumar, Ajit Bavari, Sina Hakami, Ramin M. Kashanchi, Fatah TI Reactive oxygen species activate NF kappa B (p65) and p53 and induce apoptosis in RVFV infected liver cells SO VIROLOGY LA English DT Article DE Reactive oxygen species; p65; p53; Apoptosis; Liver cells; Rift Valley fever virus ID RIFT-VALLEY-FEVER; HEPATITIS-C-VIRUS; DEPENDENT PROTEIN-KINASE; LOW ABUNDANCE BIOMARKERS; OXIDATIVE STRESS; NSS PROTEIN; STRUCTURAL PROTEINS; HYDROGEL PARTICLES; DOWN-REGULATION; MESSENGER-RNA AB Rift Valley fever virus (RVFV) infection is often associated with pronounced liver damage. Previously, our studies revealed altered host phospho-signaling responses (NF kappa B, MAPK and DNA damage responses) in RVFV infected epithelial cells that correlated with a cellular stress response. Here, we report that RVFV infection of liver cells leads to an increase in reactive oxygen species (ROS). Our data suggests the presence of the viral protein NSs in the mitochondria of infected cells, hence contributing to early increase in ROS. Increased ROS levels correlated with activation of NF kappa B (p65) and p53 responses, which in conjunction with infection, was also reflected as macromolecular rearrangements observed using size fractionation of protein lysates. Additionally, we documented an increase in cytokine expression and pro-apoptotic gene expression with infection, which was reversed with antioxidant treatment. Collectively, we identified ROS and oxidative stress as critical contributors to apoptosis of liver cells during RVFV infection. (C) 2013 Elsevier Inc. All rights reserved. C1 [Narayanan, Aarthi; Amaya, Moushimi; Voss, Kelsey; Chung, Myung; Benedict, Ashwini; Sampey, Gavin; Kehn-Hall, Kylene; Bailey, Charles; Hakami, Ramin M.; Kashanchi, Fatah] George Mason Univ, Natl Ctr Biodef & Infect Dis, Manassas, VA USA. [Narayanan, Aarthi; Amaya, Moushimi; Voss, Kelsey; Chung, Myung; Benedict, Ashwini; Sampey, Gavin; Kehn-Hall, Kylene; Bailey, Charles; Hakami, Ramin M.; Kashanchi, Fatah] George Mason Univ, Sch Syst Biol, Manassas, VA USA. [Luchini, Alessandra; Liotta, Lance] George Mason Univ, Ctr Appl Prote & Personalized Med, Manassas, VA USA. [Kumar, Ajit] George Washington Med Sch, Washington, DC USA. [Bavari, Sina] US Army, Med Res Inst Infect Dis, Frederick, MD USA. RP Kashanchi, F (reprint author), George Mason Univ, Natl Ctr Biodef & Infect Dis, Discovery Hall,Room 182,10900 Univ Blvd,MS 1H8, Manassas, VA USA. EM fkashanc@gmu.edu RI Kehn-Hall, Kylene/I-5752-2013; Luchini, Alessandra/M-5340-2014; OI Luchini, Alessandra/0000-0003-1599-0214 FU United States Department of Energy grant [DE-FC52-04NA25455]; USAMRIID [W81XWH-11-P-0310] FX The authors would like to thank Dr. Shinji Makino (UTMB) for the MP-12dNSs, MP-12 Delta NSm, MP-12-Flag-NSs, and MP-12 Delta NSs-GFP viruses. The authors thank members of the CAPMM laboratory at GMU for assistance with experiments involving the hydrogel nanoparticles. This work was supported by a United States Department of Energy grant DE-FC52-04NA25455 to FK and CB and USAMRIID contract funding W81XWH-11-P-0310 to RMH. NR 93 TC 13 Z9 16 U1 0 U2 6 PU ACADEMIC PRESS INC ELSEVIER SCIENCE PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA SN 0042-6822 J9 VIROLOGY JI Virology PD JAN 20 PY 2014 VL 449 BP 270 EP 286 DI 10.1016/j.virol.2013.11.023 PG 17 WC Virology SC Virology GA 295CL UT WOS:000330094100031 PM 24418562 ER PT J AU Huang, YM Rueda, LM AF Huang, Yiau-Min Rueda, Leopoldo M. TI A pictorial key to the species of Aedes (Ochlerotatus and Coetzeemyia) in the Afrotropical Region (Diptera: Culicidae) SO ZOOTAXA LA English DT Article DE Culicidae; mosquitoes; identification key; Africa ID ALLIED TAXA DIPTERA; LIFE STAGES; MORPHOLOGICAL DATA; AEDINI DIPTERA; CLASSIFICATION; PHYLOGENY; SUBGENERA AB Six species of the subgenus Ochlerotatus and one species of the subgenus Coetzeemyia of the genus Aedes in the Afrotropical Region are treated in a pictorial key based on diagnostic morphological features. Brief remarks on the new reclassification of the genus Aedes are also included. C1 [Huang, Yiau-Min] Smithsonian Inst, Dept Entomol, Washington, DC 20013 USA. [Rueda, Leopoldo M.] Walter Reed Army Inst Res, Walter Reed Biosyst Unit, Entomol Branch, Silver Spring, MD 20910 USA. RP Rueda, LM (reprint author), Smithsonian Inst, Walter Reed Biosystemat Unit, Museum Support Ctr MRC 534, 4210 Silver Hill Rd, Suitland, MD 20746 USA. EM huangy@si.edu; ruedapol@si.edu NR 30 TC 3 Z9 3 U1 1 U2 4 PU MAGNOLIA PRESS PI AUCKLAND PA PO BOX 41383, AUCKLAND, ST LUKES 1030, NEW ZEALAND SN 1175-5326 EI 1175-5334 J9 ZOOTAXA JI Zootaxa PD JAN 17 PY 2014 VL 3754 IS 5 BP 592 EP 600 PG 9 WC Zoology SC Zoology GA 289RD UT WOS:000329698800005 PM 24869710 ER PT J AU Sadler, JM Toulan, FR Nguyen, APT Kayea, RV Ziaee, S Palmese, GR La Scala, JJ AF Sadler, Joshua M. Toulan, Faye R. Nguyen, Anh-Phuong T. Kayea, Ronald V., III Ziaee, Saeed Palmese, Giuseppe R. La Scala, John J. TI Isosorbide as the structural component of bio-based unsaturated polyesters for use as thermosetting resins SO CARBOHYDRATE POLYMERS LA English DT Article DE Bio-based; Carbohydrate-based; Carbohydrate derived; Isosorbide; Renewable; Unsaturated polyester resin; Thermoset ID VINYL-ESTER RESINS; INFRARED SPECTROSCOPY; ACID; NETWORKS; MONOMERS AB In recent years, the development of renewable bio-based resins has gained interest as potential replacements for petroleum based resins. Modified carbohydrate-based derivatives have favorable structural features such as fused bicyclic rings that offer promising candidates for the development of novel renewable polymers with improved thermomechanical properties when compared to early bio-based resins. Isosorbide is one such compound and has been utilized as the stiffness component for the synthesis of novel unsaturated polyesters (UPE) resins. Resin blends of BioUPE systems with styrene were shown to possess viscosities (120-2200 cP) amenable to a variety of liquid molding techniques, and after cure had T(g)s (53-107 degrees C) and storage moduli (430-1650 MPa) that are in the desired range for composite materials. These investigations show that BioUPEs containing isosorbide can be tailored during synthesis of the prepolymer to meet the needs of different property profiles. (C) 2013 Elsevier Ltd. All rights reserved. C1 [Sadler, Joshua M.; Toulan, Faye R.; Nguyen, Anh-Phuong T.; Kayea, Ronald V., III; La Scala, John J.] Army Res Lab, RDRL WMM C, Aberdeen Proving Ground, MD 21005 USA. [Ziaee, Saeed] Winona State Univ, Composite Mat Engn Dept, Winona, MN 55987 USA. [Palmese, Giuseppe R.] Dept Chem & Biol Engn, Philadelphia, PA 19104 USA. RP La Scala, JJ (reprint author), Army Res Lab, RDRL WMM C, 4600 Deer Creek Loop, Aberdeen Proving Ground, MD 21005 USA. EM joshua.sadler1.ctr@mail.mil; john.j.lascala.civ@mail.mil FU U.S. Department of Defense, through the Strategic Environmental Research and Development Program (SERDP) [WP-1758]; Environmental Quality Basic Research Development Program; Postgraduate Research Participation Program at the U.S. Army Research Laboratory; U.S. Department of Energy; Dynamic Science, Inc. (DSI) FX The authors would like to thank Cytec Industries for providing the styrene free Viapal 450 unsaturated polyester resin. This research was supported by the U.S. Department of Defense, through the Strategic Environmental Research and Development Program (SERDP WP-1758) and the Environmental Quality Basic Research Development Program administered by the Armaments Research and Development Engineering Command. This research was also supported in part by an appointment to the Postgraduate Research Participation Program at the U.S. Army Research Laboratory administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the U.S. Department of Energy and USARL. This research was supported in part by an interagency agreement between Dynamic Science, Inc. (DSI) and U.S. Army Research Laboratory. NR 32 TC 14 Z9 14 U1 3 U2 74 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0144-8617 EI 1879-1344 J9 CARBOHYD POLYM JI Carbohydr. Polym. PD JAN 16 PY 2014 VL 100 SI SI BP 97 EP 106 DI 10.1016/j.carbpol.2013.04.036 PG 10 WC Chemistry, Applied; Chemistry, Organic; Polymer Science SC Chemistry; Polymer Science GA 295BQ UT WOS:000330092000014 PM 24188843 ER PT J AU Parlin, NJ Davids, WG Nagy, E Cummins, T AF Parlin, Nicholas J. Davids, William G. Nagy, Edwin Cummins, Toney TI Dynamic response of lightweight wood-based flexible wall panels to blast and impulse loading SO CONSTRUCTION AND BUILDING MATERIALS LA English DT Article DE Blast; Wood panels; Composite-reinforced wood; Pressure-impulse diagrams ID OF-FREEDOM MODELS; DIAGRAMS AB Recent research led to the development of lightweight, rapidly erected, structural wall panels constructed from solid sawn 2 x 4 softwood lumber studs and plywood sheathing coated in e-glass reinforcing. The objective of this study was to experimentally and numerically assess the dynamic blast response of these FRP-reinforced wood panels and explore the development of pressure-impulse (PI) diagrams based on a maximum deflection damage criterion. The results of five different field blast tests on the wall panels are reported. Laboratory pseudo-static bending tests of panels under fully reversed loading were performed to determine the panel's load-deformation properties. A hysteretic load-deformation model was calibrated to the blast and pseudo-static bend data and used in a nonlinear, numerically integrated SDOF dynamic response model. PI diagrams were generated using both linear and nonlinear dynamic analysis. The results of this study indicate that the blast response of the wall panels can be reasonably represented with a nonlinear SDOF dynamic model. However, the model results are sensitive to the parameters of the, hysteretic model. The results also indicate that PI diagrams are a potentially valuable tool for assessing damage under a variety of blast loads. (C) 2013 Elsevier Ltd. All rights reserved, C1 [Parlin, Nicholas J.] Univ Maine, Dept Civil & Environm Engn, Orono, ME 04469 USA. [Parlin, Nicholas J.] Univ Maine, AEWC Adv Struct & Composites Lab, Orono, ME USA. [Davids, William G.] Univ Maine, Dept Civil & Environm Engn, Orono, ME 04469 USA. [Nagy, Edwin] Kleinschmidt Energy & Water Resources Consultants, Pittsfield, ME USA. [Cummins, Toney] US Army Engn Res & Dev Ctr, Geotech & Struct Lab, Vicksburg, MS USA. RP Davids, WG (reprint author), Univ Maine, Dept Civil & Environm Engn, Orono, ME 04469 USA. EM william.davids@umit.maine.edu FU U.S. Army Corps of Engineers FX The research reported in this paper was supported by a cooperative research agreement with the U.S. Army Corps of Engineers. The authors are grateful for this support. Permission to publish was granted by the Director, Geotechnical and Structures Laboratory. NR 21 TC 2 Z9 2 U1 0 U2 8 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0950-0618 EI 1879-0526 J9 CONSTR BUILD MATER JI Constr. Build. Mater. PD JAN 15 PY 2014 VL 50 BP 237 EP 245 DI 10.1016/j.conbuildmat.2013.09.046 PG 9 WC Construction & Building Technology; Engineering, Civil; Materials Science, Multidisciplinary SC Construction & Building Technology; Engineering; Materials Science GA 300UJ UT WOS:000330489200028 ER PT J AU Peterson, M Aboudara, M AF Peterson, Matthew Aboudara, Matthew TI IMAGES IN PULMONARY, CRITICAL CARE, SLEEP MEDICINE AND THE SCIENCES SO AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE LA English DT Editorial Material C1 [Peterson, Matthew] Tripler Army Med Ctr, Dept Med, Internal Med Serv, Honolulu, HI 96859 USA. [Aboudara, Matthew] Tripler Army Med Ctr, Dept Med, Pulm Serv, Honolulu, HI 96859 USA. RP Peterson, M (reprint author), Tripler Army Med Ctr, Dept Med, Internal Med Serv, Honolulu, HI 96859 USA. NR 4 TC 0 Z9 0 U1 0 U2 0 PU AMER THORACIC SOC PI NEW YORK PA 25 BROADWAY, 18 FL, NEW YORK, NY 10004 USA SN 1073-449X EI 1535-4970 J9 AM J RESP CRIT CARE JI Am. J. Respir. Crit. Care Med. PD JAN 15 PY 2014 VL 189 IS 2 BP E4 EP E5 DI 10.1164/rccm.201303-0480IM PG 2 WC Critical Care Medicine; Respiratory System SC General & Internal Medicine; Respiratory System GA 290VG UT WOS:000329785900001 PM 24428661 ER PT J AU Diaz-Arrastia, R Kochanek, PM Bergold, P Kenney, K Marx, CE Grimes, JB Loh, Y Adam, GE Oskvig, D Curley, KC Salzer, W AF Diaz-Arrastia, Ramon Kochanek, Patrick M. Bergold, Peter Kenney, Kimbra Marx, Christine E. Grimes, Jamie B. Loh, Yince Adam, Gina E. Oskvig, Devon Curley, Kenneth C. Salzer, Wanda TI Pharmacotherapy of Traumatic Brain Injury: State of the Science and the Road Forward: Report of the Department of Defense Neurotrauma Pharmacology Workgroup SO JOURNAL OF NEUROTRAUMA LA English DT Review DE animal studies; head trauma; human studies; pharmacology; traumatic brain injury ID SPINAL-CORD-INJURY; CLOSED-HEAD INJURY; RECOMBINANT-HUMAN-ERYTHROPOIETIN; RANDOMIZED CONTROLLED-TRIAL; CONTROLLED CORTICAL IMPACT; PLACEBO-CONTROLLED TRIAL; SEX STEROID-HORMONES; ATTENTION DEFICIT/HYPERACTIVITY DISORDER; POTENTIAL NEUROPROTECTIVE MECHANISM; ANEURYSMAL SUBARACHNOID HEMORRHAGE AB Despite substantial investments by government, philanthropic, and commercial sources over the past several decades, traumatic brain injury (TBI) remains an unmet medical need and a major source of disability and mortality in both developed and developing societies. The U.S. Department of Defense neurotrauma research portfolio contains more than 500 research projects funded at more than $700 million and is aimed at developing interventions that mitigate the effects of trauma to the nervous system and lead to improved quality of life outcomes. A key area of this portfolio focuses on the need for effective pharmacological approaches for treating patients with TBI and its associated symptoms. The Neurotrauma Pharmacology Workgroup was established by the U.S. Army Medical Research and Materiel Command (USAMRMC) with the overarching goal of providing a strategic research plan for developing pharmacological treatments that improve clinical outcomes after TBI. To inform this plan, the Workgroup (a) assessed the current state of the science and ongoing research and (b) identified research gaps to inform future development of research priorities for the neurotrauma research portfolio. The Workgroup identified the six most critical research priority areas in the field of pharmacological treatment for persons with TBI. The priority areas represent parallel efforts needed to advance clinical care; each requires independent effort and sufficient investment. These priority areas will help the USAMRMC and other funding agencies strategically guide their research portfolios to ensure the development of effective pharmacological approaches for treating patients with TBI. C1 [Diaz-Arrastia, Ramon] Uniformed Serv Univ Hlth Sci, Dept Neurol, Bethesda, MD 20814 USA. [Kochanek, Patrick M.] Univ Pittsburgh, Sch Med, Dept Crit Care Med, Pittsburgh, PA USA. [Bergold, Peter] Suny Downstate Med Ctr, Dept Physiol & Pharmacol, Brooklyn, NY 11203 USA. [Kenney, Kimbra] Uniformed Serv Univ Hlth Sci, Dept Neurol, Rockville, MD USA. [Marx, Christine E.] Duke Univ, Med Ctr, Dept Psychiat & Behav Sci, Durham, NC USA. [Marx, Christine E.] Durham VA Med Ctr, Durham, NC USA. [Grimes, Jamie B.] Def & Vet Brain Injury Ctr, Silver Spring, MD USA. [Loh, Yince] Madigan Army Med Ctr, Dept Neurol, Tacoma, WA 98431 USA. [Adam, Gina E.; Curley, Kenneth C.; Salzer, Wanda] US Army Med Res & Mat Command, Ft Detrick, MD USA. RP Diaz-Arrastia, R (reprint author), Uniformed Serv Univ Hlth Sci, Dept Neurol, 4310 Jones Bridge Rd, Bethesda, MD 20814 USA. EM Ramon.Diaz-Arrastia@usuhs.edu RI Kochanek, Patrick/D-2371-2015; OI Kochanek, Patrick/0000-0002-2627-913X; Bergold, Peter/0000-0002-6335-1380 FU U.S Medical Research and Materiel Command [09127004, W81XWH-10-1-0623, W81XWH-09-2-0187]; National Institutes of Health [RO1070512, 1U44NS070324]; VA Career Development Transition Award FX Dr. Bergold is supported by the grant 09127004 from the U.S Medical Research and Materiel Command and an RO1070512 grant from the National Institutes of Health. Dr. Kochanek is supported by grants W81XWH-10-1-0623 and W81XWH-09-2-0187 from the U.S Medical Research and Materiel Command and grant 1U44NS070324 from the National Institutes of Health. Dr. Marx is a recipient of the VA Career Development Transition Award (CEM) and would like to acknowledge the support she receives. NR 265 TC 40 Z9 40 U1 3 U2 54 PU MARY ANN LIEBERT, INC PI NEW ROCHELLE PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA SN 0897-7151 EI 1557-9042 J9 J NEUROTRAUM JI J. Neurotrauma PD JAN 15 PY 2014 VL 31 IS 2 BP 135 EP 158 DI 10.1089/neu.2013.3019 PG 24 WC Critical Care Medicine; Clinical Neurology; Neurosciences SC General & Internal Medicine; Neurosciences & Neurology GA 291ZE UT WOS:000329870600001 PM 23968241 ER PT J AU Lu, YY Kotoka, R Ligda, JP Cao, BB Yarmolenko, SN Schuster, BE Wei, Q AF Lu, Y. Y. Kotoka, R. Ligda, J. P. Cao, B. B. Yarmolenko, S. N. Schuster, B. E. Wei, Q. TI The microstructure and mechanical behavior of Mg/Ti multilayers as a function of individual layer thickness SO ACTA MATERIALIA LA English DT Article DE Multilayered nanofilm; Magnesium; Titanium; Microstructure; Strength ID SCALE-DEPENDENT DEFORMATION; NANOSCALE METALLIC MULTILAYERS; TITANIUM SINGLE-CRYSTALS; STRAIN-RATE SENSITIVITY; CU/NB MULTILAYERS; NANOLAYERED COMPOSITES; ELEVATED-TEMPERATURES; PLASTIC-DEFORMATION; ULTRAFINE GRAIN; NONBASAL SLIP AB We have used magnetron sputtering to deposit magnesium and titanium layers alternately onto a single-crystal silicon substrate with equal individual layer thickness (h, from 2.5 to 200 nm) to form multilayers. We have investigated the mechanical behavior of the multilayers and its dependence on h. Transmission electron microscopy and X-ray diffraction analyses suggest that the multilayers exhibit strong texture with respect to Mg (0 0 0 2) and Ti (0 0 0 2) with an epitaxial growth pattern. Two primary orientation relationships between Ti and Mg have been identified, depending on h. Instrumented nanoindentation and microcompression have been used to examine the hardness/strength and the strain rate sensitivity of the multilayers. Based on nanoindentation, we have found that the strength of these multilayers generally increases as h is decreased. The microcompression measured strength is remarkably higher than that derived from indentation. The Hall-Petch law can be used to interpret the increase in strength at relatively large h (>50 nm), while the confined layer slip model provides a better explanation for the relationship between strength and h at smaller h. We have also attempted to present an in-depth discussion about the applicability of relevant strengthening mechanisms on these hexagonal close-packed/hexagonal close-packed multilayers. (C) 2013 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved. C1 [Lu, Y. Y.; Cao, B. B.; Wei, Q.] Univ N Carolina, Dept Mech Engn, Charlotte, NC 28223 USA. [Kotoka, R.; Yarmolenko, S. N.] N Carolina Agr & Tech State Univ, Dept Mech Engn, Greensboro, NC 27411 USA. [Ligda, J. P.; Schuster, B. E.] US Army Res Lab, WMRD, Aberdeen, MD 21005 USA. RP Wei, Q (reprint author), Univ N Carolina, Dept Mech Engn, Charlotte, NC 28223 USA. EM qwei@uncc.ed RI Wei, Qiuming/B-7579-2008; Cao, Baobao/E-9110-2011; Yarmolenko, Sergey/E-6819-2017 FU Education Ministry of the People's Republic of China; US Army Research Laboratory [W911QX-08-C-0073]; National Science Foundation through ERC FX Y.Y.L. expresses her gratitude to the Education Ministry of the People's Republic of China for the financial support during her graduate study at the University of North Carolina at Charlotte. Q.W. has been supported by the US Army Research Laboratory under Contract No. W911QX-08-C-0073. S.N.Y. has been supported by National Science Foundation through ERC. NR 102 TC 22 Z9 23 U1 4 U2 63 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 1359-6454 EI 1873-2453 J9 ACTA MATER JI Acta Mater. PD JAN 15 PY 2014 VL 63 BP 216 EP 231 DI 10.1016/j.actamat.2013.10.032 PG 16 WC Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering SC Materials Science; Metallurgy & Metallurgical Engineering GA 287OM UT WOS:000329552100021 ER PT J AU Schneider, NS Zukas, WS Pomerantz, NL AF Schneider, Nathaniel S. Zukas, Walter S. Pomerantz, Natalie L. TI Effect of cation exchange on dimethyl methylphosphonate permeation kinetics in a pentablock hydrocarbon ionomer and a perfluorocarbon ionomer SO POLYMER LA English DT Article DE Diffusion; Immobilization; Relaxation ID TRANSIENT PERMEATION; TRIBLOCK COPOLYMERS; DIFFUSION; CAPACITIES; TRANSPORT; MEMBRANE; POLYMERS AB The present work is concerned with the effect of cation exchange, with calcium, aluminum and cupric cations, on the permeation kinetics of dimethyl methylphosphonate (DMMP) in a pentablock ionomer (Nexar (TM)) and a perfluoroionomer (Nafion (TM)). The diffusion constant was determined by matching a Fickian solution to early time data, with a zero-time shift, initially attributed to the effect of immobilization. The diffusion time-lag relation was applied in an expanded form to include contributions of immobilization and relaxation. The primary effect of cation exchange was a marked reduction in diffusion constant and introduction of significant relaxation. The effects were explored in a two step procedure in which the sample was first exposed to DMMP vapor at activity 0.6 and then at activity 0.8. In cation modified Nexar at the lower activity the delay in onset of permeation was due solely to immobilization. The delay was absent at the higher activity, indicating that extent of immobilization was unchanged with increased concentration, but approach to steady state was still relaxation controlled. In cation modified Nafion delay in onset of permeation was dominated by relaxation, but kinetics at the higher activity was essentially Fickian. The strong relaxation effects appear to be a consequence of cation modification, which results in a network of ionic crosslinks formed by multivalent cation-sulfonate interactions. The combined analytical and experimental procedure developed in this study provided a systematic set of values for the effect of cation exchange and ionomer characteristics on parameters controlling DMMP permeation kinetics. Published by Elsevier Ltd. C1 [Schneider, Nathaniel S.; Zukas, Walter S.; Pomerantz, Natalie L.] US Army Res Dev & Engn Command, Dept Army, WarSTAR Directorate, Natick Soldier Ctr, Natick, MA 01760 USA. RP Schneider, NS (reprint author), US Army Res Dev & Engn Command, Dept Army, WarSTAR Directorate, Natick Soldier Ctr, 15 Kansas St, Natick, MA 01760 USA. EM nathaniel.s.schneider.ctr@mail.mil NR 22 TC 0 Z9 0 U1 0 U2 6 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0032-3861 EI 1873-2291 J9 POLYMER JI Polymer PD JAN 14 PY 2014 VL 55 IS 1 SI SI BP 150 EP 159 DI 10.1016/j.polymer.2013.12.004 PG 10 WC Polymer Science SC Polymer Science GA 296TA UT WOS:000330207100019 ER PT J AU Yeh, IC Rinderspacher, BC Andzelm, JW Cureton, LT La Scala, J AF Yeh, In-Chul Rinderspacher, B. Christopher Andzelm, Jan W. Cureton, LaShonda T. La Scala, John TI Computational study of thermal and mechanical properties of nylons and bio-based furan polyamides SO POLYMER LA English DT Article DE Molecular dynamics; Furan polyamides; Mechanical properties ID MOLECULAR-DYNAMICS SIMULATION; NANOCONFINED POLYAMIDE-6,6; AMORPHOUS POLYSTYRENE; BRILL TRANSITION; GLASS-TRANSITION; WATER INFLUENCE; LOCAL-STRUCTURE; FORCE-FIELD; TEMPERATURE; PHASE AB We have investigated thermal and mechanical properties of bio-based furan polyamides and petroleum-based nylons with atomistic simulations. Glass transition temperatures estimated from a series of simulations at different temperatures were in good agreement with experimental measurements. Stress -strain relationships under uniaxial deformation conditions were also obtained and analyzed. Overall, polymers with smaller repeat units exhibited slightly higher glass transition temperatures and elastic moduli, which were attributed to higher cohesive energy densities. Furan polyamides displayed higher van der Waals cohesive energy densities and maintained more rigid planar structures near furan rings compared to nylons. As a result, bio-based furan polyamides showed higher glass transition temperatures and comparable mechanical properties despite having overall weaker hydrogen bonding than nylons. Published by Elsevier Ltd. C1 [Yeh, In-Chul; Rinderspacher, B. Christopher; Andzelm, Jan W.] US Army Res Lab, Mat & Mfg Sci Div, Macromol Sci & Technol Branch, Aberdeen Proving Ground, MD 21005 USA. [Cureton, LaShonda T.; La Scala, John] US Army Res Lab, Mat & Mfg Sci Div, Coatings Corros & Engn Polymers Branch, Aberdeen Proving Ground, MD 21005 USA. RP Andzelm, JW (reprint author), US Army Res Lab, Mat & Mfg Sci Div, Macromol Sci & Technol Branch, Aberdeen Proving Ground, MD 21005 USA. EM jan.w.andzelm.civ@mail.mil; john.j.lascala.civ@mail.mil FU Postgraduate Research Participation Program at the U.S. Army Research Laboratory (ARL); Computing Challenge Project [C5M] FX This work was supported in part by an appointment to the Postgraduate Research Participation Program at the U.S. Army Research Laboratory (ARL) administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the U.S. Department of Energy and ARL. The DoD HPC Modernization Office supported this project by supplying supercomputer time under the Computing Challenge Project C5M. NR 51 TC 12 Z9 12 U1 4 U2 54 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0032-3861 EI 1873-2291 J9 POLYMER JI Polymer PD JAN 14 PY 2014 VL 55 IS 1 SI SI BP 166 EP 174 DI 10.1016/j.polymer.2013.11.009 PG 9 WC Polymer Science SC Polymer Science GA 296TA UT WOS:000330207100021 ER PT J AU Batyrev, IG Taylor, DE Gazonas, GA McCauley, JW AF Batyrev, I. G. Taylor, D. E. Gazonas, G. A. McCauley, J. W. TI Density functional theory and evolution algorithm calculations of elastic properties of AlON SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID ALUMINUM OXYNITRIDE; O SYSTEM; PRESSURE; SPINEL; MODEL AB Different models for aluminum oxynitride (AlON) were calculated using density functional theory and optimized using an evolutionary algorithm. Evolutionary algorithm and density functional theory (DFT) calculations starting from several models of AlON with different Al or O vacancy locations and different positions for the N atoms relative to the vacancy were carried out. The results show that the constant anion model [McCauley et al., J. Eur. Ceram. Soc. 29(2), 223 (2009)] with a random distribution of N atoms not adjacent to the Al vacancy has the lowest energy configuration. The lowest energy structure is in a reasonable agreement with experimental X-ray diffraction spectra. The optimized structure of a 55 atom unit cell was used to construct 220 and 440 atom models for simulation cells using DFT with a Gaussian basis set. Cubic elastic constant predictions were found to approach the experimentally determined AlON single crystal elastic constants as the model size increased from 55 to 440 atoms. The pressure dependence of the elastic constants found from simulated stress-strain relations were in overall agreement with experimental measurements of polycrystalline and single crystal AlON. Calculated IR intensity and Raman spectra are compared with available experimental data. C1 [Batyrev, I. G.; Taylor, D. E.; Gazonas, G. A.; McCauley, J. W.] US Army, Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Batyrev, IG (reprint author), US Army, Res Lab, Aberdeen Proving Ground, MD 21005 USA. OI Gazonas, George/0000-0002-2715-016X NR 19 TC 5 Z9 5 U1 3 U2 32 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0021-8979 EI 1089-7550 J9 J APPL PHYS JI J. Appl. Phys. PD JAN 14 PY 2014 VL 115 IS 2 AR 023505 DI 10.1063/1.4859435 PG 6 WC Physics, Applied SC Physics GA 292SN UT WOS:000329922700017 ER PT J AU Kesim, MT Cole, MW Zhang, J Misirlioglu, IB Alpay, SP AF Kesim, M. T. Cole, M. W. Zhang, J. Misirlioglu, I. B. Alpay, S. P. TI Tailoring dielectric properties of ferroelectric-dielectric multilayers SO APPLIED PHYSICS LETTERS LA English DT Article ID THIN-FILMS; TUNABILITY; SUPERLATTICES AB We develop a nonlinear thermodynamic model for multilayer ferroelectric heterostructures that takes into account electrostatic and electromechanical interactions between layers. We concentrate on the effect of relative layer fractions and in-plane thermal stresses on dielectric properties of Ba0.6Sr0.4TiO3-, BaTiO3-, and PbZr0.2Ti0.8O3 (PZT)-SrTiO3 (STO) multilayers on Si and c-sapphire. We show that dielectric properties of such multilayers can be significantly enhanced by tailoring the growth/processing temperature and the STO layer fraction. Our computations show that large tunabilities (similar to 90% at 400 kV/cm) are possible in carefully designed barium strontium titanate-STO and PZT-STO even on Si for which there exist substantially large in-plane strains. (C) 2014 AIP Publishing LLC. C1 [Kesim, M. T.; Zhang, J.; Alpay, S. P.] Univ Connecticut, Dept Mat Sci & Engn, Storrs, CT 06269 USA. [Kesim, M. T.; Zhang, J.; Alpay, S. P.] Univ Connecticut, Inst Mat Sci, Storrs, CT 06269 USA. [Cole, M. W.] US Army Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. [Misirlioglu, I. B.] Sabanci Univ, Fac Engn & Nat Sci, TR-34956 Istanbul, Turkey. [Alpay, S. P.] Univ Connecticut, Dept Phys, Storrs, CT 06269 USA. RP Alpay, SP (reprint author), Univ Connecticut, Dept Mat Sci & Engn, Storrs, CT 06269 USA. EM p.alpay@ims.uconn.edu RI Alpay, Pamir/E-2666-2013 NR 31 TC 10 Z9 10 U1 1 U2 57 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 0003-6951 EI 1077-3118 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD JAN 13 PY 2014 VL 104 IS 2 AR 022901 DI 10.1063/1.4861716 PG 4 WC Physics, Applied SC Physics GA 299YG UT WOS:000330431000081 ER PT J AU McWilliams, B Yu, J Klier, E Yen, CF AF McWilliams, B. Yu, J. Klier, E. Yen, C. -F. TI Mechanical response of discontinuous ceramic fiber reinforced metal matrix composites under quasi-static and dynamic loadings SO MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING LA English DT Article DE Metal matrix composites; Ballistic performance; Mechanical characterization; Failure mechanisms; Digital image correlation ID VISCOPLASTIC DAMAGE MODEL; PARTICLE DISTRIBUTION; BEHAVIOR; COMPRESSION; PENETRATION; PERFORATION; STRENGTH; SAFFIL; IMPACT AB The quasi-static mechanical properties and ballistic impact performance of several discontinuous ceramic fiber (Saffil) reinforced Al-2% Cu metal matrix composites (MMC) are characterized. The ballistic penetration resistance of the materials are determined against a fragment simulating projectile and compared to the performance of the baseline matrix alloy. Digital image correlation with high speed photography is used to measure the full field deflection of the materials during impact. Mechanical behavior and post-mortem fracture analysis are used to relate material properties to performance in penetrating and non-penetrating impact events. It is demonstrated that the MMC materials exhibit a strong asymmetry in their tensile and compressive responses. The MMC materials are stronger in compression and the asymmetry in response increases with increasing volume fraction of fiber. It was found that the ballistic performance (V-50(BL)) decreases when the volume fraction of fiber is greater than 3% due to the decrease in tensile strain to failure at higher volume fractions. In non-penetrating impacts the increased stiffness and strength with higher volume fractions greatly reduces the magnitude and distribution of plate deflection. (C) 2013 Elsevier B.V. All rights reserved. C1 [McWilliams, B.] Oak Ridge Inst Sci & Educ, Aberdeen Proving Ground, MD 21005 USA. [Yu, J.; Klier, E.; Yen, C. -F.] US Army Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD USA. RP McWilliams, B (reprint author), Oak Ridge Inst Sci & Educ, ATTN WMM B, Bldg 4600, Aberdeen Proving Ground, MD 21005 USA. EM brandon.a.mcwilliams.ctr@mail.mil NR 26 TC 9 Z9 10 U1 3 U2 18 PU ELSEVIER SCIENCE SA PI LAUSANNE PA PO BOX 564, 1001 LAUSANNE, SWITZERLAND SN 0921-5093 EI 1873-4936 J9 MAT SCI ENG A-STRUCT JI Mater. Sci. Eng. A-Struct. Mater. Prop. Microstruct. Process. PD JAN 10 PY 2014 VL 590 BP 21 EP 29 DI 10.1016/j.msea.2013.09.068 PG 9 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering SC Science & Technology - Other Topics; Materials Science; Metallurgy & Metallurgical Engineering GA 292FV UT WOS:000329888500004 ER PT J AU Hines, DC Videen, G Zubko, E Muinonen, K Shkuratov, Y Kaydash, VG Knight, MM Sitko, ML Lisse, CM Mutchler, M Hammer, D Yanamandra-Fisher, PA AF Hines, Dean C. Videen, Gorden Zubko, Evgenij Muinonen, Karri Shkuratov, Yuriy Kaydash, Vadim G. Knight, Matthew M. Sitko, Michael L. Lisse, Carey M. Mutchler, Max Hammer, Derek Yanamandra-Fisher, Padmavati A. TI HUBBLE SPACE TELESCOPE PRE-PERIHELION ACS/WFC IMAGING POLARIMETRY OF COMET ISON (C/2012 S1) AT 3.81 AU SO ASTROPHYSICAL JOURNAL LETTERS LA English DT Article DE comets: general; comets: individual (C/2012 S1 (ISON)); instrumentation: polarimeters; techniques: polarimetric ID LINEAR-POLARIZATION; OPTICAL POLARIMETRY; PHASE ANGLES; INNER COMA; DUST; PARTICLES; LIGHT; P/HALLEY; NICMOS; WAVELENGTH AB We present polarization images of Comet ISON (C/2012 S1) taken with the Hubble Space Telescope (HST) on UTC 2013 May 8 (r(h) = 3.81 AU, Delta = 4.34 AU), when the phase angle was alpha approximate to 12.degrees 16. This phase angle is approximately centered in the negative polarization branch for cometary dust. The region beyond 1000 km (similar to 0.32 arcsec approximate to 6 pixels) from the nucleus shows a negative polarization amplitude of p% similar to -1.6%. Within 1000 km of the nucleus, the polarization position angle rotates to be approximately perpendicular to the scattering plane, with an amplitude p% similar to +2.5%. Such positive polarization has been observed previously as a characteristic feature of cometary jets, and we show that Comet ISON does indeed harbor a jet-like feature. These HST observations of Comet ISON represent the first visible light, imaging polarimetry with subarcsecond spatial resolution of a Nearly Isotropic Comet beyond 3.8 AU from the Sun at a small phase angle. The observations provide an early glimpse of the properties of the cometary dust preserved in this Oort-Cloud comet. C1 [Hines, Dean C.; Mutchler, Max; Hammer, Derek] Space Telescope Sci Inst, Baltimore, MD 21218 USA. [Hines, Dean C.; Videen, Gorden; Sitko, Michael L.; Yanamandra-Fisher, Padmavati A.] Space Sci Inst, Boulder, CO 80301 USA. [Videen, Gorden] US Army Res Lab, Adelphi, MD 20783 USA. [Zubko, Evgenij; Muinonen, Karri] Univ Helsinki, Dept Phys, FI-00014 Helsinki, Finland. [Zubko, Evgenij; Shkuratov, Yuriy; Kaydash, Vadim G.] VN Karazin Univ, Astron Inst, UA-61058 Kharkov, Ukraine. [Muinonen, Karri] Finnish Geodet Inst, FI-02431 Masala, Finland. [Shkuratov, Yuriy] Radioastron Inst NASU, UA-61002 Kharkov, Ukraine. [Knight, Matthew M.] Lowell Observ, Flagstaff, AZ 86001 USA. [Knight, Matthew M.; Lisse, Carey M.] Johns Hopkins Univ, Appl Phys Lab, Laurel, MD 20723 USA. [Sitko, Michael L.] Univ Cincinnati, Dept Phys, Cincinnati, OH 45221 USA. RP Hines, DC (reprint author), Space Telescope Sci Inst, 3700 San Martin Dr, Baltimore, MD 21218 USA. RI Lisse, Carey/B-7772-2016; OI Lisse, Carey/0000-0002-9548-1526; Knight, Matthew/0000-0003-2781-6897 FU NASA through a grant from the Space Telescope Science Institute [GO 13199]; NASA [NAS5-26555]; SAEMPL ERC Advanced Grant (Scattering and Absorption of Electromagnetic Waves in Particulate Media) [320773]; Academy of Finland [257966] FX We wish to thank A. C. Levasseur-Regourd for a careful reading of the manuscript, and for suggestions that have enhanced its clarity. We also thank L. Kolokolova for useful discussions. We also acknowledge the anonymous referee for comments that have improved the manuscript significantly. Support for program number GO 13199 was provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS5-26555. Additional funding by the SAEMPL ERC Advanced Grant No. 320773 (Scattering and Absorption of Electromagnetic Waves in Particulate Media) and the Academy of Finland contract No. 257966. NR 50 TC 8 Z9 8 U1 0 U2 2 PU IOP PUBLISHING LTD PI BRISTOL PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND SN 2041-8205 EI 2041-8213 J9 ASTROPHYS J LETT JI Astrophys. J. Lett. PD JAN 10 PY 2014 VL 780 IS 2 AR L32 DI 10.1088/2041-8205/780/2/L32 PG 6 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA 279XW UT WOS:000328993700018 ER PT J AU Shukla, MK Hill, F AF Shukla, Manoj K. Hill, Frances TI Dissociative Adsorption of 5-Nitro-2,4-dihydro-3H-1,2,4-triazol-3-one (NTO) on Aluminum-Terminated (0001) Surface of alpha-Alumina As Predicted from Plane-Wave Density Functional Theory SO JOURNAL OF PHYSICAL CHEMISTRY C LA English DT Article ID ALPHA-AL2O3(0001) SURFACE; 3-NITRO-1,2,4-TRIAZOL-5-ONE NTO; DECOMPOSITION; CRYSTAL; TAUTOMERISM; EXPLOSIVES; ENERGETICS; AL2O3; SALTS; FATE AB Plane wave density functional theory (DFT) was used to study the adsorption of 5-nitro-2,4-dihydro-3H-1,2,4-triazol-3-one (NTO), an insensitive high performance explosive material, on Al-terminated (0001) surface of (4 X 4) alpha-Al2O3 using the PBE, PBEsol, BLIP, and recently developed van der Waals functional (vdW-DF2) within the Generalized Gradient Approximation. The interactions of valence electrons with atomic cores were approximated using the ultrasoft pseudopotentials. Various orientations of NTO with respect to the alumina surface were considered. It was revealed that the carbonyl site of NTO binds more strongly than the nitro group site with the surface aluminum ion. Important information revealed from the present investigation was that NTO undergoes dissociative adsorption on the Al-terminated alpha-alumina surface. During this process, both the carbonyl oxygen and the nitro oxygen are involved in binding with surface Al ions and a proton from the N4 site of the adsorbate (NTO) is dissociated and migrated to nearby surface oxygen site forming an OH bond. Consequently, the NTO adsorbed on the alumina surface is in the anionic form. Further, consequent to the adsorption, the interacting surface Al-atoms are pulled up toward the NTO with respect to the plane containing the rest of the Al atoms. Moreover, an analysis of charge density difference maps suggested a buildup of charge density in the NTO-alumina bonding region, indicating covalent nature of adsorption on the Al-terminated (0001) surface of alpha-alumina. C1 [Shukla, Manoj K.; Hill, Frances] US Army Engn Res & Dev Ctr, Environm Lab, Vicksburg, MS 39180 USA. RP Shukla, MK (reprint author), US Army Engn Res & Dev Ctr, Environm Lab, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM Manoj.K.Shukla@usace.army.mil NR 54 TC 3 Z9 3 U1 3 U2 16 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1932-7447 J9 J PHYS CHEM C JI J. Phys. Chem. C PD JAN 9 PY 2014 VL 118 IS 1 BP 310 EP 319 DI 10.1021/jp408661h PG 10 WC Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Chemistry; Science & Technology - Other Topics; Materials Science GA 289JL UT WOS:000329678200035 ER PT J AU Walz, AJ Hsu, FL AF Walz, Andrew J. Hsu, Fu-Lian TI Synthesis of 4-anilinopiperidine methyl esters, intermediates in the production of carfentanil, sufentanil, and remifentanil SO TETRAHEDRON LETTERS LA English DT Article DE Anilinopiperidine methyl esters; Cyclization; Sufentanil; Carfentanil; Remifentanil; N,N-Dimethylformamide dimethyl acetal ID PHARMACOLOGICAL EVALUATION; OPIOID ANALGESICS; CONVERSION; FACILE; POTENT; AMIDES; ROUTE AB Two spirodiaza intermediates have been made and employed in the synthesis of 4-anilinopiperidine methyl esters. These intermediates can be utilized in the production of commercial synthetic analgesics carfentanil, sufentanil, and remifentanil. Published by Elsevier Ltd. C1 [Walz, Andrew J.; Hsu, Fu-Lian] US Army, ECBC, Res & Technol Directorate, Aberdeen Proving Ground, MD 21010 USA. RP Walz, AJ (reprint author), US Army, ECBC, Res & Technol Directorate, Aberdeen Proving Ground, MD 21010 USA. EM andrew.j.walz.civ@mail.mil FU Defense Threat Reduction Agency-Joint Science and Technology Office (DTRA-JSTO) [CBCALL12-TAS-2-0130] FX The authors would like to thank Dr. Sari Paikoff at the Defense Threat Reduction Agency-Joint Science and Technology Office (DTRA-JSTO) for funding this work under contract (CBCALL12-TAS-2-0130). NR 20 TC 0 Z9 0 U1 3 U2 24 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0040-4039 J9 TETRAHEDRON LETT JI Tetrahedron Lett. PD JAN 8 PY 2014 VL 55 IS 2 BP 501 EP 502 DI 10.1016/j.tetlet.2013.11.058 PG 2 WC Chemistry, Organic SC Chemistry GA 293BR UT WOS:000329946900051 ER PT J AU Marcsisin, SR Sousa, JC Reichard, GA Caridha, D Zeng, Q Roncal, N McNulty, R Careagabarja, J Sciotti, RJ Bennett, JW Zottig, VE Deye, G Li, QG Read, L Hickman, M Nanayakkara, NPD Walker, LA Smith, B Melendez, V Pybus, BS AF Marcsisin, Sean R. Sousa, Jason C. Reichard, Gregory A. Caridha, Diana Zeng, Qiang Roncal, Norma McNulty, Ronan Careagabarja, Julio Sciotti, Richard J. Bennett, Jason W. Zottig, Victor E. Deye, Gregory Li, Qigui Read, Lisa Hickman, Mark Nanayakkara, N. P. Dhammika Walker, Larry A. Smith, Bryan Melendez, Victor Pybus, Brandon S. TI Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds SO MALARIA JOURNAL LA English DT Article ID PLASMODIUM-VIVAX MALARIA; HUMAN CYTOCHROME-P450 2D6; DRUG PRIMAQUINE; GENETIC POLYMORPHISMS; IN-VITRO; FALCIPARUM; EFFICACY; PROPHYLAXIS; REGIMENS; ERYTHROCYTES AB Background: Tafenoquine (TQ) is an 8-aminoquinoline (8AQ) that has been tested in several Phase II and Phase III clinical studies and is currently in late stage development as an anti-malarial prophylactic agent. NPC-1161B is a promising 8AQ in late preclinical development. It has recently been reported that the 8AQ drug primaquine requires metabolic activation by CYP 2D6 for efficacy in humans and in mice, highlighting the importance of pharmacogenomics in the target population when administering primaquine. A logical follow-up study was to determine whether CYP 2D activation is required for other compounds in the 8AQ structural class. Methods: In the present study, the anti-malarial activities of NPC-1161B and TQ were assessed against luciferase expressing Plasmodium berghei in CYP 2D knock-out mice in comparison with normal C57BL/6 mice (WT) and with humanized/CYP 2D6 knock-in mice by monitoring luminescence with an in vivo imaging system. These experiments were designed to determine the direct effects of CYP 2D metabolic activation on the anti-malarial efficacy of NPC-1161B and TQ. Results: NPC-1161B and TQ exhibited no anti-malarial activity in CYP 2D knock-out mice when dosed at their ED100 values (1 mg/kg and 3 mg/kg, respectively) established in WT mice. TQ anti-malarial activity was partially restored in humanized/CYP 2D6 knock-in mice when tested at two times its ED100. Conclusions: The results reported here strongly suggest that metabolism of NPC-1161B and TQ by the CYP 2D enzyme class is essential for their anti-malarial activity. Furthermore, these results may provide a possible explanation for therapeutic failures for patients who do not respond to 8AQ treatment for relapsing malaria. Because CYP 2D6 is highly polymorphic, variable expression of this enzyme in humans represents a significant pharmacogenomic liability for 8AQs which require CYP 2D metabolic activation for efficacy, particularly for large-scale prophylaxis and eradication campaigns. C1 [Marcsisin, Sean R.; Sousa, Jason C.; Reichard, Gregory A.; Caridha, Diana; Zeng, Qiang; Roncal, Norma; McNulty, Ronan; Careagabarja, Julio; Sciotti, Richard J.; Zottig, Victor E.; Deye, Gregory; Li, Qigui; Read, Lisa; Hickman, Mark; Melendez, Victor; Pybus, Brandon S.] Walter Reed Army Inst Res, Mil Malaria Res Program, Div Expt Therapeut, Silver Spring, MD 20910 USA. [Bennett, Jason W.] Walter Reed Army Inst Res, Malaria Vaccine Branch, Mil Malaria Res Program, Silver Spring, MD 20910 USA. [Nanayakkara, N. P. Dhammika; Walker, Larry A.] Univ Mississippi, Ctr Nat Prod Res, Oxford, MS 38677 USA. [Walker, Larry A.] Univ Mississippi, Dept Pharmacol, Sch Pharm, Oxford, MS 38677 USA. [Smith, Bryan] US Army Med Mat Dev Act, Frederick, MD 21701 USA. RP Marcsisin, SR (reprint author), Walter Reed Army Inst Res, Mil Malaria Res Program, Div Expt Therapeut, 503 Robert Grant Ave, Silver Spring, MD 20910 USA. EM sean.r.marcsisin.mil@mail.mil NR 33 TC 27 Z9 27 U1 3 U2 11 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1475-2875 J9 MALARIA J JI Malar. J. PD JAN 3 PY 2014 VL 13 AR 2 DI 10.1186/1475-2875-13-2 PG 9 WC Infectious Diseases; Parasitology; Tropical Medicine SC Infectious Diseases; Parasitology; Tropical Medicine GA 297HV UT WOS:000330247400001 PM 24386891 ER PT J AU Sambanthamoorthy, K Luo, CY Pattabiraman, N Feng, XR Koestler, B Waters, CM Palys, TJ AF Sambanthamoorthy, Karthik Luo, Chunyuan Pattabiraman, Nagarajan Feng, Xiarong Koestler, Benjamin Waters, Christopher M. Palys, Thomas J. TI Identification of small molecules inhibiting diguanylate cyclases to control bacterial biofilm development SO BIOFOULING LA English DT Article DE Acinetobacter; biofilm; Pseudomonas; small molecule antagonist; anti-infective; c-di-GMP ID C-DI-GMP; PSEUDOMONAS-FLUORESCENS PF0-1; CYCLIC DIGUANYLATE; KLEBSIELLA-PNEUMONIAE; SYSTEMATIC ANALYSIS; MICROBIAL BIOFILMS; AERUGINOSA PAO1; PROTEIN DOMAIN; EAL DOMAINS; GGDEF AB Biofilm formation by pathogenic bacteria is an important virulence factor in the development of numerous chronic infections, thereby causing a severe health burden. Many of these infections cannot be resolved, as bacteria in biofilms are resistant to the host's immune defenses and antibiotic therapy. An urgent need for new strategies to treat biofilm-based infections is critically needed. Cyclic di-GMP (c-di-GMP) is a widely conserved second-messenger signal essential for biofilm formation. The absence of this signalling system in higher eukaryotes makes it an attractive target for the development of new anti-biofilm agents. In this study, the results of an in silico pharmacophore-based screen to identify small-molecule inhibitors of diguanylate cyclase (DGC) enzymes that synthesize c-di-GMP are described. Four small molecules, LP 3134, LP 3145, LP 4010 and LP 1062 that antagonize these enzymes and inhibit biofilm formation by Pseudomonas aeruginosa and Acinetobacter baumannii in a continuous-flow system are reported. All four molecules dispersed P. aeruginosa biofilms and inhibited biofilm development on urinary catheters. One molecule dispersed A. baumannii biofilms. Two molecules displayed no toxic effects on eukaryotic cells. These molecules represent the first compounds identified from an in silico screen that are able to inhibit DGC activity to prevent biofilm formation. C1 [Sambanthamoorthy, Karthik; Luo, Chunyuan; Feng, Xiarong; Palys, Thomas J.] Walter Reed Army Inst Res, Silver Spring, MD 20910 USA. [Pattabiraman, Nagarajan] Molbox, Silver Spring, MD USA. [Koestler, Benjamin; Waters, Christopher M.] Michigan State Univ, Dept Microbiol & Mol Genet, E Lansing, MI 48824 USA. RP Palys, TJ (reprint author), Walter Reed Army Inst Res, Silver Spring, MD 20910 USA. EM thomas.palys1@us.army.mil OI Koestler, Benjamin/0000-0001-7213-0953 FU Military Infectious Diseases Research Program (MIDRP) [W0066_12_WR]; NIH [U19AI090872]; MSU Foundation FX The findings and opinions expressed herein belong to the authors and do not necessarily reflect the official views of the WRAIR, the US Army, or the Department of Defense. This work was supported by a Military Infectious Diseases Research Program (MIDRP) grant W0066_12_WR awarded to Dr CL which provided support for KS also and NIH grants U19AI090872 and the MSU Foundation to CMW. The authors would like to thank Matthew Wise from the microscopy facility at WRAIR for providing help with the imaging when necessary, the Michigan State University Mass Spectrometry facility for assistance in quantifying c-di-GMP, Dr. Iswarduth Soojhawon for helping with figures and Dr. Matthew Parsek for sharing P. aeruginosa strains. NR 48 TC 20 Z9 20 U1 3 U2 12 PU TAYLOR & FRANCIS LTD PI ABINGDON PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND SN 0892-7014 EI 1029-2454 J9 BIOFOULING JI Biofouling PD JAN 2 PY 2014 VL 30 IS 1 BP 17 EP 28 DI 10.1080/08927014.2013.832224 PG 12 WC Biotechnology & Applied Microbiology; Marine & Freshwater Biology SC Biotechnology & Applied Microbiology; Marine & Freshwater Biology GA AH0SO UT WOS:000335830800002 PM 24117391 ER PT J AU Nault, ME Netherland, MD Mikulyuk, A Skogerboe, JG Asplund, T Hauxwell, J Toshner, P AF Nault, Michelle E. Netherland, Michael D. Mikulyuk, Alison Skogerboe, John G. Asplund, Tim Hauxwell, Jennifer Toshner, Pamela TI Efficacy, selectivity, and herbicide concentrations following a whole-lake 2,4-D application targeting Eurasian watermilfoil in two adjacent northern Wisconsin lakes SO LAKE AND RESERVOIR MANAGEMENT LA English DT Article DE 2,4-dichlorophenoxy acetic acid; aquatic plant management; chemical control; herbicide; invasive species; Myriophyllum spicatum; native macrophytes ID FLURIDONE TREATMENTS; PLANT-COMMUNITIES; ELISA METHOD; MACROPHYTES; VEGETATION; RESIDUES; IMPACTS; COST AB The herbicide 2,4-D (2,4-dichlorophenoxy acetic acid) has been used to control the nonnative aquatic plant Eurasian watermilfoil (Myriophyllum spicatum; EWM) since the 1950s. Although published research evaluates the herbicide's predicted and observed concentration and exposure times in both laboratory and field settings, few data are available evaluating selectivity and long-term efficacy as well as herbicide concentration behavior following large-scale, whole-lake applications. A controlled study was conducted on 2 adjacent oligo-mesotrophic northern Wisconsin lakes to determine the potential efficacy and selectivity of large-scale and low-dose 2,4-D applications. Initial 2,4-D concentrations in both treated lakes were approximately 100g/L higher than the nominal lakewide targets of 500 and 275g/L, respectively, and the herbicide dissipated and degraded more slowly than predicted. A lakewide regression model relating 2,4-D concentration at monitoring sites to days after treatment (DAT) found the mean half-life of 2,4-D to be 34-41 DAT, and the threshold for irrigation of plants not labeled for direct treatment with 2,4-D (<100g/L) was not met until 50-93 DAT. In the lake treated at the higher 2,4-D rate, EWM was not detected for 3 consecutive years posttreatment. Additionally, several native monocotyledon and dicotyledon species also showed sustained significant declines posttreatment. This study is the first to link field-collected 2,4-D concentration measurements to selectivity and long-term efficacy in EWM control following whole-lake management efforts. Although multiyear EWM control was achieved with these single low-dose applications, longer than expected herbicide persistence and impacts to native plants demonstrate the challenges facing aquatic plant managers and the need for additional field studies. C1 [Nault, Michelle E.; Mikulyuk, Alison; Asplund, Tim; Hauxwell, Jennifer] Wisconsin Dept Nat Resources, Madison, WI 53716 USA. [Netherland, Michael D.; Skogerboe, John G.] US Army, Engn Res & Dev Ctr, Ctr Aquat & Invas Plants, Gainesville, FL 32653 USA. [Toshner, Pamela] Wisconsin Dept Nat Resources, Spooner, WI 54801 USA. RP Nault, ME (reprint author), Wisconsin Dept Nat Resources, 2801 Progress Rd, Madison, WI 53716 USA. EM michelle.nault@wisconsin.gov FU Wisconsin Department of Natural Resources FX The authors thank Frank Koshere, Martha Barton, Meghan Porzky, Kelly Wagner, Scott Van Egeren, Alex Smith, Paul Frater, Kari Soltau, Jesse Schwingle, Michael Fell, Jeremy Bates, and Stefania Strzalkowska for assistance in field and laboratory. We appreciate the partnership of the Town of Barnes Aquatic Invasive Species Committee, specifically Ingemar Ekstrom who coordinated project management, as well as Ron Clark, Gus Gustafson, Jim Joswick, and Glenda Mattila who collected herbicide concentration samples. We also thank the editor and reviewers for valuable input and comments that improved the manuscript. This study was completed thanks to financial support from aquatic invasive species grants and technical assistance funds from the Wisconsin Department of Natural Resources as provided under s. 23.22 (2)(c). NR 35 TC 4 Z9 4 U1 2 U2 21 PU TAYLOR & FRANCIS INC PI PHILADELPHIA PA 520 CHESTNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA SN 1040-2381 EI 2151-5530 J9 LAKE RESERV MANAGE JI Lake Reserv. Manag. PD JAN 2 PY 2014 VL 30 IS 1 BP 1 EP 10 DI 10.1080/10402381.2013.862586 PG 10 WC Limnology; Marine & Freshwater Biology; Water Resources SC Marine & Freshwater Biology; Water Resources GA AB2CE UT WOS:000331599800001 ER PT J AU Chen, JYC Oden, RVN Merritt, JO AF Chen, Jessie Y. C. Oden, Razia V. N. Merritt, John O. TI Utility of stereoscopic displays for indirect-vision driving and robot teleoperation SO ERGONOMICS LA English DT Article DE stereoscopic display; human-robot interaction; indirect-vision driving; simulation; military; visual discomfort ID 3D DISPLAYS; PERCEPTION; PERFORMANCE; SURGERY; HAZARDS; 2D AB The effectiveness of an active shutter-glasses stereoscopic display (SD) and a passive polarised SD was evaluated in a live robot-teleoperation task and a simulated indirect-vision driving task in various terrains. Overall, participants completed their tasks significantly faster with the SDs in three-dimensional (3D) mode than with the SDs in the baseline 2D mode. They also navigated more accurately with the SDs in 3D mode. When the effectiveness of the two types of SDs was examined separately, results showed that the active shutter-glasses SD resulted in faster responses and task completion times than the passive polarised SD, though most of the differences failed to reach statistical significance. Perceived workload when interacting with the two SD systems did not differ significantly between the active versus passive display types or between the 3D and 2D modes of operation; however, participants reported more severe discomfort after interacting with the passive polarised SD. Practitioner Summary: This study demonstrated the utility of SDs for enhancing operators' navigation-related performance. The results furthered the understanding of the differential effectiveness of an active stereoscopic system versus a passive system. The findings will facilitate the implementation of stereoscopic systems for robotics control and indirect-vision driving in military settings. C1 [Chen, Jessie Y. C.] US Army Res Lab, Human Res & Engn Directorate, Orlando, FL 32826 USA. [Oden, Razia V. N.] Design Interact Inc, Oviedo, FL USA. [Merritt, John O.] Merritt Grp, Williamsburg, MA USA. RP Chen, JYC (reprint author), US Army Res Lab, Human Res & Engn Directorate, Orlando, FL 32826 USA. EM jessie.chen@us.army.mil FU PEO Integration FX This project was funded by PEO Integration. NR 33 TC 6 Z9 6 U1 0 U2 7 PU TAYLOR & FRANCIS LTD PI ABINGDON PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND SN 0014-0139 EI 1366-5847 J9 ERGONOMICS JI Ergonomics PD JAN 2 PY 2014 VL 57 IS 1 BP 12 EP 22 DI 10.1080/00140139.2013.859739 PG 11 WC Engineering, Industrial; Ergonomics; Psychology, Applied; Psychology SC Engineering; Psychology GA 303RW UT WOS:000330692900003 PM 24308626 ER PT J AU Sambaluk, NM AF Sambaluk, Nicholas Michael TI US policymakers confront aerospace doctrine, 1957-59 SO COLD WAR HISTORY LA English DT Article AB Soviet satellites in 1957 galvanised air force interest in defending and exploiting aerospace' as an extended realm of operations. The Dynamic Soarer glider programme, catapulted to significance by air force reaction to Sputnik, became the standard bearer for aerospace thought in the late 1950s. Dwight Eisenhower's administration, however, did not see the weaponisation of space as inevitable or desirable. Convinced that public insistence for visible space accomplishments made elimination or cuts to projects politically difficult, Eisenhower's administration used organisational decisions and policy strictures to impede development of the Dyna-Soar and to prevent aerospace paladins from commandeering US space policy. C1 US Mil Acad, Dept Hist, West Point, NY 10996 USA. RP Sambaluk, NM (reprint author), US Mil Acad, Dept Hist, West Point, NY 10996 USA. EM nicholas.sambaluk@usma.edu NR 36 TC 0 Z9 0 U1 0 U2 2 PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD PI ABINGDON PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND SN 1468-2745 EI 1743-7962 J9 COLD WAR HIST JI Cold War Hist. PD JAN 2 PY 2014 VL 14 IS 1 BP 91 EP 107 DI 10.1080/14682745.2013.782536 PG 17 WC History SC History GA 274IX UT WOS:000328601100005 ER PT S AU Isenhour, ML Lohner, R AF Isenhour, Michelle L. Loehner, Rainald BE Daamen, W Duives, DC Hoogendoom, SP TI Verification of a pedestrian simulation tool using the NIST recommended test cases SO CONFERENCE ON PEDESTRIAN AND EVACUATION DYNAMICS 2014 (PED 2014) SE Transportation Research Procedia LA English DT Proceedings Paper CT Conference on Pedestrian and Evacuation Dynamics (PED) CY OCT 22-24, 2014 CL Delft, NETHERLANDS DE pedestrian modeling; simulation tool; verification; evacuation; force-based pedestrian model AB In an attempt to develop a verification and validation standard for building fire evacuation models, Ronchi et al. (2013) at the United States' National Institute of Standards and Technology (NIST) recommended a set of seventeen verification tests. We found that the application of these verification tests allowed us to make rather significant improvements to our simulation code (PEDFLOW) for approximately half of the recommended tests (Table 1). In some cases, we added capabilities that did not exist before. In other cases, we found anomalous behaviors and adjusted the existing code to remove these unexplained behaviors. This paper summarizes the work on the verification tests, highlighting the lessons learned and modifications made. We also discuss some modifications we recommend to the NIST verification tests, as well as demonstrate how to make these tests suitable for all pedestrian flow models (not just building fire evacuation). Published by Elsevier B.V. C1 [Isenhour, Michelle L.] US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. [Loehner, Rainald] George Mason Univ, Coll Sci, Dept Computat & Data Sci, CFD Ctr, Fairfax, VA 22030 USA. RP Isenhour, ML (reprint author), US Mil Acad, Dept Math Sci, 601 Thayer Rd, West Point, NY 10996 USA. EM michelle.isenhour@usma.edu NR 7 TC 3 Z9 3 U1 0 U2 0 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 2352-1465 J9 TRANSP RES PROC PY 2014 VL 2 BP 237 EP 245 DI 10.1016/j.trpro.2014.09.042 PG 9 WC Mathematics, Interdisciplinary Applications; Social Sciences, Mathematical Methods; Transportation; Transportation Science & Technology SC Mathematics; Mathematical Methods In Social Sciences; Transportation GA BE0MM UT WOS:000366304000030 ER PT S AU Isenhour, ML Lohner, R AF Isenhour, Michelle L. Loehner, Rainald BE Daamen, W Duives, DC Hoogendoom, SP TI Validation of a pedestrian simulation tool using the NIST stairwell evacuation data SO CONFERENCE ON PEDESTRIAN AND EVACUATION DYNAMICS 2014 (PED 2014) SE Transportation Research Procedia LA English DT Proceedings Paper CT Conference on Pedestrian and Evacuation Dynamics (PED) CY OCT 22-24, 2014 CL Delft, NETHERLANDS DE pedestrian modeling; high-rise evacuation; validation; stair-well dataset; force-based pedestrian modeling AB Researchers at the United States National Institute of Standards and Technology (NIST) collected occupant egress data in the stairwells of several high-rise buildings for potential use in quantitative and qualitative validation of evacuation simulation tools (Kuligowski and Peacock (2010)). We found this data suitable for establishing occupant initial locations, pre-evacuation time distributions, and other parametric inputs for our simulation code (PEDFLOW). With this data set, we were able to validate several core behavioral components of PEDFLOW by directly comparing actual versus predicted values for occupant speed on stairs and building total evacuation times. This paper summarizes our work on the stairwell data sets, highlighting the methodology behind the extraction of values for the parametric inputs, and demonstrating the results obtained for one specific 10-story high-rise building data-set. Published by Elsevier B.V. C1 [Isenhour, Michelle L.] US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. [Loehner, Rainald] George Mason Univ, Coll Sci, Dept Computat & Data Sci, CFD Ctr, Fairfax, VA 22030 USA. RP Isenhour, ML (reprint author), US Mil Acad, Dept Math Sci, 601 Thayer Rd, West Point, NY 10996 USA. EM michelle.isenhour@usma.edu NR 6 TC 0 Z9 0 U1 1 U2 2 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 2352-1465 J9 TRANSP RES PROC PY 2014 VL 2 BP 739 EP 744 DI 10.1016/j.trpro.2014.09.082 PG 6 WC Mathematics, Interdisciplinary Applications; Social Sciences, Mathematical Methods; Transportation; Transportation Science & Technology SC Mathematics; Mathematical Methods In Social Sciences; Transportation GA BE0MM UT WOS:000366304000097 ER PT J AU West, AL Griep, MH Cole, DP Karna, SP AF West, Abby L. Griep, Mark H. Cole, Dan P. Karna, Shashi P. GP IEEE TI Gold Nanocluster-DNase 1 Hybrid Materials for DNA Contamination Sensing SO 2014 IEEE 14TH INTERNATIONAL CONFERENCE ON NANOTECHNOLOGY (IEEE-NANO) LA English DT Proceedings Paper CT 14th IEEE International Conference on Nanotechnology (IEEE-NANO) CY AUG 14-21, 2014 CL Toronto, CANADA SP IEEE ID REAL-TIME PCR; HIGHLY FLUORESCENT; DIRECTED SYNTHESIS; QUANTUM DOTS; CLUSTERS; SAMPLES; GLUTATHIONE AB Protein encapsulated gold nanocluster (P-AuNC) synthesis was first demonstrated in 2009.[1] Initially these P-AuNCs were used as cellular imaging agents as the protein shell surrounding the AuNC made them highly biocompatible. However, recent studies have begun to show that these stabilizing proteins may also retain native biological function thus giving a dual functionality to these hybrid molecules. Here we present the synthesis of DNase 1 stabilized gold nanoclusters (DNase 1:AuNCs) with core sizes consisting either 8 or 25 atoms. The DNase 1:Au8NCs exhibit blue fluorescence whereas the DNase 1:Au25NCs are red emitting. Moreover, in addition to the intense fluorescence emission; the synthesized DNase 1: AuNC hybrid retain the native functionality of the protein, allowing simultaneous detection and digestion of DNA with a detection limit of 2 mu g/mL (Scheme 1). The DNase 1:AuNCs could be conveniently employed as efficient and fast sensors to augment the current inefficient and time consuming DNA contamination analysis techniques. C1 [West, Abby L.; Griep, Mark H.; Karna, Shashi P.] US Army, Res Lab, ATTN RDRL WM, Aberdeen Proving Ground, MD 21005 USA. [Cole, Dan P.] US Army, Res Lab, ATTN RDRL VT, Aberdeen Proving Ground, MD 21005 USA. RP West, AL (reprint author), US Army, Res Lab, ATTN RDRL WM, Aberdeen Proving Ground, MD 21005 USA. EM abby.west2.ctr@mail.mil; mark.h.griep.civ@mail.mil; daniel.p.cole.ctr@mail.mil; shashi.p.karna.civ@mail.mil NR 29 TC 0 Z9 0 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-5622-7 PY 2014 BP 32 EP 36 PG 5 WC Computer Science, Theory & Methods; Engineering, Electrical & Electronic; Nanoscience & Nanotechnology SC Computer Science; Engineering; Science & Technology - Other Topics GA BD9ZF UT WOS:000365620600009 ER PT J AU Parsons, P Duncan, K Karna, SP Xiao, JQ AF Parsons, Paul Duncan, Kate Karna, Shashi P. Xiao, John Q. GP IEEE TI Tailored Electromagnetic Properties of NiZn Nanocomposite Materials SO 2014 IEEE 14TH INTERNATIONAL CONFERENCE ON NANOTECHNOLOGY (IEEE-NANO) LA English DT Proceedings Paper CT 14th IEEE International Conference on Nanotechnology (IEEE-NANO) CY AUG 14-21, 2014 CL Toronto, CANADA SP IEEE DE Nanomagnetics; Nanomaterials: Synthesis and Characterization; Applications and Enabled Systems AB Nickel-zinc ferrite nanoparticles with compositions of NixZn1-xFe2O4, where x = 0.1 - 0.9, were synthesized using a water-based precipitation technique. These nanoparticles were then calcined at high temperature to improve crystallinity and were characterized to determine their magnetic and dielectric properties. After selecting the synthesized composition with the most favorable magnetodielectric properties and dispersing it into a polymer matrix, we can tailor the permeability and permittivity based on the fraction of filler loading. The nanoparticles and nanocomposites were characterized using standard technologies for structural, physical, and electromagnetic properties. C1 [Parsons, Paul; Karna, Shashi P.] US Army, Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. [Parsons, Paul] Univ Delaware, Dept Mat Sci & Engn, Newark, DE 19716 USA. [Duncan, Kate] US Army, Commun Elect Res Dev & Engn Ctr, Space & Terr Commun Directorate, Aberdeen Proving Ground, MD 21005 USA. [Xiao, John Q.] Univ Delaware, Dept Phys & Astron, Newark, DE 19716 USA. RP Parsons, P (reprint author), Univ Delaware, Dept Mat Sci & Engn, Newark, DE 19716 USA. EM pparsons@udel.edu NR 16 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-5622-7 PY 2014 BP 87 EP 91 PG 5 WC Computer Science, Theory & Methods; Engineering, Electrical & Electronic; Nanoscience & Nanotechnology SC Computer Science; Engineering; Science & Technology - Other Topics GA BD9ZF UT WOS:000365620600019 ER PT J AU Hall, A Gaston, J Wolde, W Baker, E Okada, M Wang, YH Karna, S AF Hall, Asha Gaston, Jeremy Wolde, Wosen Baker, Edwards Okada, Morihiro Wang, YuHuang Karna, Shashi GP IEEE TI Signal Conditioning of Carbon Nanotube Thin Film Loudspeakers SO 2014 IEEE 14TH INTERNATIONAL CONFERENCE ON NANOTECHNOLOGY (IEEE-NANO) LA English DT Proceedings Paper CT 14th IEEE International Conference on Nanotechnology (IEEE-NANO) CY AUG 14-21, 2014 CL Toronto, CANADA SP IEEE DE Thermophone; Carbon Nanotube thin film loudspeaker AB Super-aligned carbon nanotube (CNT) thin films offer the capability to be placed into compact lightweight sound sources for active noise control, loudspeaker, or other acoustic applications. The super-aligned CNT films generate thermoacoustically induced oscillations to generate sound. This occurs through the use of a dynamic signal, such as applying an alternating current in the audio frequency range to the thin film. This mechanism is carried out through joule heating which heats the air above the surface, thereby producing sound waves from periodic air vibration. Here, we report an investigation of the sound pressure and thermal properties of advanced carbon nanotube thin films with an emphasis to address the signal distortion issue. C1 [Hall, Asha; Wolde, Wosen] US Army Res Lab, Vehicle Technol Directorate, Aberdeen Proving Ground, MD 21005 USA. [Gaston, Jeremy] US Army Res Lab, Human Res Engn Directorate, Aberdeen Proving Ground, MD 21005 USA. [Baker, Edwards; Okada, Morihiro; Wang, YuHuang] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA. [Karna, Shashi] US Army Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. RP Hall, A (reprint author), US Army Res Lab, Vehicle Technol Directorate, Aberdeen Proving Ground, MD 21005 USA. EM asha.j.hall.civ@mail.mil NR 7 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-5622-7 PY 2014 BP 668 EP 671 PG 4 WC Computer Science, Theory & Methods; Engineering, Electrical & Electronic; Nanoscience & Nanotechnology SC Computer Science; Engineering; Science & Technology - Other Topics GA BD9ZF UT WOS:000365620600152 ER PT J AU Griep, MH Tay, R Tumlin, T Mallick, G Tsang, SH Singh, RS Teo, EHT Karna, SP AF Griep, Mark H. Tay, Roland Tumlin, Travis Mallick, Govind Tsang, Siu Hon Singh, Ram Sevak Teo, Edwin Hang Ton Karna, Shashi P. GP IEEE TI Surface Energy Controlled Growth of Single Crystalline Two-Dimensional Hexagonal (h)-Boron Nitride SO 2014 IEEE 14TH INTERNATIONAL CONFERENCE ON NANOTECHNOLOGY (IEEE-NANO) LA English DT Proceedings Paper CT 14th IEEE International Conference on Nanotechnology (IEEE-NANO) CY AUG 14-21, 2014 CL Toronto, CANADA SP IEEE ID BORON-NITRIDE; COPPER; FILMS AB Two-dimensional (2D) nanomaterials, including graphene and boron nitride (BN), have been of intense interest in recent years due to their exceptional electronic, thermal, and mechanical properties. Tailoring these novel properties to their maximum potential requires precise control of the atomic layer growth process. In recent years, catalytic growth of 2-D nanomaterials using chemical vapor deposition (CVD) process has emerged as an attractive approach due to their low-cost, scalalibility, and ability to transfer the grown materials on various substrates. In this approach, the morphology and purity of the catalytic surface plays a critical role on the shape, size, and growth kintectics of the 2D nanomaterial. In this work, we present the results of our systematic studies of the role of catalytic surface morphology on the shape and domain size of CVD grown hexagonal (h)-BN films. The present work clearly demonstrates that the presence of surface roghness in the form of ridges leads to a preferential growth of small-domain triangular BN sheets. A 100-fold reduction in the surfcae roughness leads to increased domain BN triangles, eventually transitioning to large-domain hexagonal shaped BN sheets. C1 [Griep, Mark H.; Tumlin, Travis; Mallick, Govind; Karna, Shashi P.] US Army Res Lab, ATTN RDRL WM, Aberdeen Proving Ground, MD 21005 USA. [Tay, Roland; Mallick, Govind; Tsang, Siu Hon; Singh, Ram Sevak; Teo, Edwin Hang Ton] Nanyang Technol Univ, Singapore 639798, Singapore. RP Griep, MH (reprint author), US Army Res Lab, ATTN RDRL WM, Aberdeen Proving Ground, MD 21005 USA. EM shashi.p.karna.civ@mail.mil RI Teo, Hang Tong Edwin/E-9437-2015 OI Teo, Hang Tong Edwin/0000-0003-0528-1764 NR 10 TC 0 Z9 0 U1 0 U2 3 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-5622-7 PY 2014 BP 900 EP 903 PG 4 WC Computer Science, Theory & Methods; Engineering, Electrical & Electronic; Nanoscience & Nanotechnology SC Computer Science; Engineering; Science & Technology - Other Topics GA BD9ZF UT WOS:000365620600209 ER PT S AU Ettisserry, DP Goldsman, N Akturk, A Lelis, AJ AF Ettisserry, D. P. Goldsman, N. Akturk, A. Lelis, A. J. GP IEEE TI Effects of carbon-related oxide defects on the reliability of 4H-SiC MOSFETs SO 2014 INTERNATIONAL CONFERENCE ON SIMULATION OF SEMICONDUCTOR PROCESSES AND DEVICES (SISPAD) SE International Conference on Simulation of Semiconductor Processes and Devices LA English DT Proceedings Paper CT International Conference on Simulation of Semiconductor Processes and Devices (SISPAD) CY SEP 09-11, 2014 CL Yokohama, JAPAN SP Japan Soc Appl Phys, Inoue Fdn Sci, Support Ctr Adv Telecommunicat Technol Res, IEEE Elect Devices Soc DE hole traps; bias-temperature instability; single-carbon interstitial; 4H-silicon carbide MOSFET ID TIME-DEPENDENCE; SIO2 AB In this work, we use density functional theory-based calculations to study the hole trapping properties of single carbon-related defects in silicon dioxide. We show that such interstitials are stable in the carboxyl configuration, where the interstitial carbon atom remains three-fold coordinated with chemical bonds to two Si atoms and an oxygen atom (Si-[C=O]-Si). Using formation energy calculations, we observed a +2 to neutral charge transition level for carboxyl defect within the 4H-SiC bandgap. This leads us to propose that carboxyl defects are likely to act as switching oxide border hole traps in the oxide and contribute to threshold voltage instabilities in a 4H-SiC MOSFET. Thus, we provide an additional candidate to the traditional oxygen vacancy hole traps in 4H-SiC MOS systems. The atomic structures of the defect in various charge states are presented. The stability-providing mechanism for the carboxyl defect in the doubly positive state is found to be the puckering of the Si atom, as in the case of positively charged oxygen vacancy hole traps. C1 [Ettisserry, D. P.; Goldsman, N.; Akturk, A.] Univ Maryland, Dept Elect & Comp Engn, College Pk, MD 20742 USA. [Lelis, A. J.] US Army Res Lab, Adelphi, MD 20783 USA. RP Ettisserry, DP (reprint author), Univ Maryland, Dept Elect & Comp Engn, College Pk, MD 20742 USA. EM deva@umd.edu OI Ettisserry, Devanarayanan/0000-0002-4214-2141 NR 20 TC 1 Z9 1 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1946-1569 BN 978-1-4799-5288-5 J9 INT CONF SIM SEMI PR PY 2014 BP 61 EP 64 PG 4 WC Engineering, Electrical & Electronic SC Engineering GA BD9LT UT WOS:000364919800016 ER PT J AU Braines, D Preece, A de Mel, G Pham, T AF Braines, Dave Preece, Alun de Mel, Geeth Tien Pham GP IEEE TI Enabling CoIST Users: D2D at the Network Edge SO 2014 17TH INTERNATIONAL CONFERENCE ON INFORMATION FUSION (FUSION) LA English DT Proceedings Paper CT 17th International Conference on Information Fusion (FUSION) CY JUL 07-10, 2014 CL Salamanca, SPAIN SP ISIF, VNiVERSiDAD Salamanca, Univ Carlos Madrid, IBM, IEEE, Indra DE ontologies; sensor-mission matching; controlled natural language; conversational interaction; data-to-decisions AB Rapid but informed decision-making capabilities at lower echelons are fast becoming a necessity in many coalition operations due to the dynamism associated with such environments. In this paper we investigate technologies to assist CoIST (Company Intelligence Support Team) users operating at the network edge in support of military operations. Through an integration experiment we illustrate the impact of such technologies in rapid decision-making situations. The paper describes the technology integration experiment in the context of a vignette and shows how a natural language conversational interface between human and machine agents in a hybrid team is used. The system can capture local information reporting, infer high value information based on background knowledge, automatically raise intelligence tracking tasks and match, rank and propose appropriate assets to tasks, taking into account contextual factors such as environmental and the distributed network conditions. The approach utilizes ontology-based resource matching capabilities and uses a Controlled Natural Language as a human-friendly - but machine processable language that is expressive enough to serve as a single common format for both human and machine processing. This capability is designed to operate in a lightweight distributed environment at the edge of the network. C1 [Braines, Dave] IBM United Kingdom Ltd, Emerging Technol Serv, Winchester, Hants, England. [Preece, Alun] Cardiff Univ, Sch Comp Sci & Informat, Cardiff CF10 3AX, S Glam, Wales. [de Mel, Geeth] IBM TJ Watson Res Ctr, Yorktown Hts, NY USA. [Tien Pham] US Army Res Lab, Adelphi, MD USA. RP Braines, D (reprint author), IBM United Kingdom Ltd, Emerging Technol Serv, Hursley Pk, Winchester, Hants, England. NR 16 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA PY 2014 PG 8 WC Computer Science, Information Systems; Computer Science, Interdisciplinary Applications; Computer Science, Theory & Methods SC Computer Science GA BD8FB UT WOS:000363896100144 ER PT J AU Damarla, T Alberts, WCK AF Damarla, Thyagaraju Alberts, W. C. Kirkpatrick, II GP IEEE TI Helicopter Tracking Using Acoustic Arrays SO 2014 17TH INTERNATIONAL CONFERENCE ON INFORMATION FUSION (FUSION) LA English DT Proceedings Paper CT 17th International Conference on Information Fusion (FUSION) CY JUL 07-10, 2014 CL Salamanca, SPAIN SP ISIF, VNiVERSiDAD Salamanca, Univ Carlos Madrid, IBM, IEEE, Indra AB Tracking of airborne vehicles using distributed acoustic arrays is considered here. Three tetrahedral acoustic arrays are distributed over roughly 1.5 sq. miles area to track a helicopter. The bearing angles are estimated at the significant harmonics of the fundamental frequency of the helicopter rotor using multiple signal classification (MUSIC). Some of the issues using the bearing estimates at lower harmonics are discussed. The altitude of the helicopter is estimated by fusing the covariances from all three arrays and performing MUSIC on them. An extended Kalman filter is used to track the helicopter and the tracking results are presented. C1 [Damarla, Thyagaraju] US Army Res Lab, Networked Sensing & Fus Branch, Adelphi, MD 20783 USA. [Alberts, W. C. Kirkpatrick, II] US Army Res Lab, Acoust & EM Sensing Branch, Adelphi, MD 20783 USA. RP Damarla, T (reprint author), US Army Res Lab, Networked Sensing & Fus Branch, Adelphi, MD 20783 USA. EM thyagaraju.damarla.civ@mail.mil; william.c.alberts4.civ@mail.mil NR 15 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA PY 2014 PG 7 WC Computer Science, Information Systems; Computer Science, Interdisciplinary Applications; Computer Science, Theory & Methods SC Computer Science GA BD8FB UT WOS:000363896100052 ER PT J AU George, J Kaplan, LM Deligeorges, S Cakiades, G AF George, Jemin Kaplan, Lance M. Deligeorges, Socrates Cakiades, George GP IEEE TI Multi-Shooter Localization using Finite Point Process SO 2014 17TH INTERNATIONAL CONFERENCE ON INFORMATION FUSION (FUSION) LA English DT Proceedings Paper CT 17th International Conference on Information Fusion (FUSION) CY JUL 07-10, 2014 CL Salamanca, SPAIN SP ISIF, VNiVERSiDAD Salamanca, Univ Carlos Madrid, IBM, IEEE, Indra ID SENSORS; SYSTEM AB A finite point process approach to multi-shooter localization from gunfire events is presented. After modeling the measurements as a Poisson point process, we propose a twofold scheme that includes an expectation maximization algorithm to estimate the target locations for a given number of targets and an information theoretic algorithm to select the number of targets. The proposed localization scheme does not require solving the data association problem and can account for clutter noise as well as missed detections. The optimal subpattern assignment metric is used to assess the performance and accuracy of the proposed localization algorithm. Implementation of the proposed algorithm on experimental data yields desirable results. C1 [George, Jemin; Kaplan, Lance M.] US Army Res Lab, Adelphi, MD 20783 USA. [Deligeorges, Socrates] BioMimetic Syst Inc, Cambridge, MA 02139 USA. [Cakiades, George] US Army Armament Res, Ctr Dev & Engn, Picatinny Arsenal, NJ 07806 USA. RP George, J (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. EM jemin.georgeciv@mail.mil; lance.m.kaplan.civ@mail.mil; socrates@bmsacoustics.com; george.cakiades.civ@mail.mil NR 22 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA PY 2014 PG 7 WC Computer Science, Information Systems; Computer Science, Interdisciplinary Applications; Computer Science, Theory & Methods SC Computer Science GA BD8FB UT WOS:000363896100261 ER PT J AU Kaplan, L Sensoy, M de Mel, G AF Kaplan, Lance Sensoy, Murat de Mel, Geeth GP IEEE TI Trust Estimation and Fusion of Uncertain Information by Exploiting Consistency SO 2014 17TH INTERNATIONAL CONFERENCE ON INFORMATION FUSION (FUSION) LA English DT Proceedings Paper CT 17th International Conference on Information Fusion (FUSION) CY JUL 07-10, 2014 CL Salamanca, SPAIN SP ISIF, VNiVERSiDAD Salamanca, Univ Carlos Madrid, IBM, IEEE, Indra ID REPUTATION AB Agents may cooperate by communicating their opinions about various phenomena. These opinions are then fused by agents and used for informed decision-making. However, fusing opinions from diverse sources is not trivial - especially in open multiagent systems - where it is not possible to ensure that the sources are honest and their opinions are not misleading. In this paper, we propose a novel approach that exploits consistencies and conflicts between personal observations and shared information to derive trust evidence for information sources. Based on the derived evidence, we describe how opinions from diverse sources can be fused. We have evaluated our approach for trust estimation and opinion fusion using a service selection scenario. Through extensive simulations, we have shown that our approach significantly outperforms the existing trust-based information fusion approaches. C1 [Kaplan, Lance] US Army Res Lab, Adelphi, MD 20783 USA. [Sensoy, Murat] Ozyegin Univ, Comp Sci, Istanbul, Turkey. [de Mel, Geeth] IBM TJ Watson Res Ctr, Yorktown Hts, NY 10598 USA. RP Kaplan, L (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. NR 16 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA PY 2014 PG 8 WC Computer Science, Information Systems; Computer Science, Interdisciplinary Applications; Computer Science, Theory & Methods SC Computer Science GA BD8FB UT WOS:000363896100112 ER PT J AU Osborne, RW Bar-Shalom, Y George, J Kaplan, L AF Osborne, Richard W., III Bar-Shalom, Yaakov George, Jemin Kaplan, Lance GP IEEE TI Data Fusion from Multiple Passive Sensors for Multiple Shooter Localization via Assignment SO 2014 17TH INTERNATIONAL CONFERENCE ON INFORMATION FUSION (FUSION) LA English DT Proceedings Paper CT 17th International Conference on Information Fusion (FUSION) CY JUL 07-10, 2014 CL Salamanca, SPAIN SP ISIF, VNiVERSiDAD Salamanca, Univ Carlos Madrid, IBM, IEEE, Indra DE acoustic localization; fusion; passive localization; assignment AB This work examines the extension of a recently developed single target acoustic localization system to multiple targets. Multiple passive sensors distributed in a region of space will detect the acoustic signal of multiple gunfire events and measure the bearing to the event as well as the time the signal was detected. In order to alleviate the data association problem, an assignment-based method was developed in order to associate measurements at a fusion center, which will provide estimates of the multiple shooter locations. The assignment based approach is shown to localize multiple closely spaced shooters with a high degree of accuracy. C1 [Osborne, Richard W., III; Bar-Shalom, Yaakov] Univ Connecticut, Dept Elect & Comp Engn, Storrs, CT 06269 USA. [George, Jemin; Kaplan, Lance] US Army Res Lab, Adelphi, MD 20783 USA. RP Osborne, RW (reprint author), Univ Connecticut, Dept Elect & Comp Engn, Storrs, CT 06269 USA. EM rosborne@engr.uconn.edu; ybs@engr.uconn.edu; jemin.george@us.army.mil; lance.m.kaplan@us.army.mil NR 19 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA PY 2014 PG 7 WC Computer Science, Information Systems; Computer Science, Interdisciplinary Applications; Computer Science, Theory & Methods SC Computer Science GA BD8FB UT WOS:000363896100126 ER PT J AU Sikdar, S Adali, S Amin, M Abdelzaher, T Chan, K Cho, JH Kang, B O'Donovan, J AF Sikdar, S. Adali, S. Amin, M. Abdelzaher, T. Chan, K. Cho, J. -H. Kang, B. O'Donovan, J. GP IEEE TI Finding True and Credible Information on Twitter SO 2014 17TH INTERNATIONAL CONFERENCE ON INFORMATION FUSION (FUSION) LA English DT Proceedings Paper CT 17th International Conference on Information Fusion (FUSION) CY JUL 07-10, 2014 CL Salamanca, SPAIN SP ISIF, VNiVERSiDAD Salamanca, Univ Carlos Madrid, IBM, IEEE, Indra AB In this paper, we present a unique study of two successful methods for computing message reliability. The first. method is based on machine learning and attempts to find a predictive model based on network features. This method is generally geared towards assessing credibility of messages and is able to generate high recall results. The second method is based on a maximum likelihood formulation and attempts to find messages that are corroborated by independent and reliable sources. This method is geared towards finding facts in which humans are treated as binary sensors and is expected to generate high accuracy results but only for those facts that have higher level of corroboration. We show that these two methods can point to similar or quite different predictions depending on the underlying data set. We then illustrate how they can be fused to capture the trade off between favoring true versus credible messages which can either be opinions or not necessarily verifiable. C1 [Sikdar, S.; Adali, S.] Rensselaer Polytech Inst, Dept Comp Sci, Troy, NY 12180 USA. [Amin, M.; Abdelzaher, T.] Univ Illinois, Dept Comp Sci, Urbana, IL 61801 USA. [Chan, K.; Cho, J. -H.] Army Res Labs, Adelphi, MD 20783 USA. [Kang, B.; O'Donovan, J.] Univ Calif Santa Barbara, Dept Comp Sci, Santa Barbara, CA 93106 USA. RP Sikdar, S (reprint author), Rensselaer Polytech Inst, Dept Comp Sci, Troy, NY 12180 USA. NR 17 TC 0 Z9 0 U1 1 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA PY 2014 PG 8 WC Computer Science, Information Systems; Computer Science, Interdisciplinary Applications; Computer Science, Theory & Methods SC Computer Science GA BD8FB UT WOS:000363896100020 ER PT B AU Hulla, JE AF Hulla, Janis E. BE Hayes, AW Kruger, CL TI Metals SO HAYES' PRINCIPLES AND METHODS OF TOXICOLOGY, 6TH EDITION LA English DT Article; Book Chapter DE Adequate intake; Contact dermatitis; Dietary reference intakes; Essential nutrients; Fenton reaction; Ferritin; Mees' lines; Metallothionein; Recommended dietary allowance; Tolerable upper intake level ID BLOOD LEAD LEVELS; NUTRITION EXAMINATION SURVEYS; SODIUM POLYSTYRENE SULFONATE; IEHR EVALUATIVE PROCESS; BORIC-ACID TOXICITY; REPRODUCTIVE TOXICITY; GALLIUM NITRATE; ALZHEIMERS-DISEASE; DEVELOPMENTAL TOXICITY; MAGNESIUM-DEFICIENCY C1 [Hulla, Janis E.] US Army Corps Engineers, Sacramento, CA 95814 USA. RP Hulla, JE (reprint author), US Army Corps Engineers, Sacramento, CA 95814 USA. NR 348 TC 0 Z9 0 U1 1 U2 1 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-84214-537-1; 978-1-84214-536-4 PY 2014 BP 825 EP 882 D2 10.1201/b17359 PG 58 WC Toxicology SC Toxicology GA BD7FA UT WOS:000362973800018 ER PT J AU Smith, SC Hammell, RJ Parker, TW Marvel, LM AF Smith, Sidney C. Hammell, Robert J., II Parker, Travis W. Marvel, Lisa M. BE Jo, JY Takahashi, S TI A Theoretical Exploration of the Impact of Packet Loss on Network Intrusion Detection SO 2014 15TH IEEE/ACIS INTERNATIONAL CONFERENCE ON SOFTWARE ENGINEERING, ARTIFICIAL INTELLIGENCE, NETWORKING AND PARALLEL/DISTRIBUTED COMPUTING (SNPD) LA English DT Proceedings Paper CT 15th IEEE/ACIS International Conference on Software Engineering, Artificial Intelligence, Networking and Parallel/Distributed Computing (SNPD) CY JUN 30-JUL 02, 2014 CL Las Vegas, NV SP IEEE, Int Assoc Comp & Informat Sci, IEEE Comp Soc DE Network Intrusion Detection Packet Loss AB In this paper we review the problem of packet loss as it pertains to Network Intrusion Detection, seeking to answer two fundamental research questions which are stepping stones towards building a model that can be used to predict the rate of alert loss based upon the rate of packet loss. The first question deals with how the packet loss rate affects the sensor alert rate, and the second considers how the network traffic composition affects the results of the first question. Potential places where packet loss may occur are examined by dividing the problem into network, host, and sensor based packets loss. We posit theories about how packet loss may present itself and develop the Packet Dropper that induces packet loss into a dataset. Drop rates ranging from 0% to 100% are applied to four different data sets and the resulting abridged data sets are analyzed with Snort to collect alert loss rate. Conclusions are drawn about the importance of the distribution of packet loss and the effect of the network traffic composition. C1 [Smith, Sidney C.; Marvel, Lisa M.] ARL, Computat Informat Sci Directorate, Aberdeen Proving Ground, MD 21005 USA. [Hammell, Robert J., II] Towson Univ, Dept Comp & Informat Sci, Towson, MD USA. [Parker, Travis W.] ICF Int, Aberdeen Proving Ground, MD USA. RP Smith, SC (reprint author), ARL, Computat Informat Sci Directorate, Aberdeen Proving Ground, MD 21005 USA. EM sidney.c.smith24.civ@mail.mil; rhammell@towson.edu; travis.w.parker16.ctr@mail.mil; lisa.m.marvel.civ@mail.mil NR 16 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-5604-3 PY 2014 BP 161 EP 166 PG 6 WC Computer Science, Artificial Intelligence; Computer Science, Hardware & Architecture; Computer Science, Software Engineering SC Computer Science GA BD7NA UT WOS:000363327800027 ER PT S AU Liao, DH AF Liao, DaHan GP IEEE TI Scattering and Imaging of Nonlinearly Loaded Antenna Structures in Half-Space Environments SO 2014 IEEE ANTENNAS AND PROPAGATION SOCIETY INTERNATIONAL SYMPOSIUM (APSURSI) SE IEEE Antennas and Propagation Society International Symposium LA English DT Proceedings Paper CT IEEE Antennas-and-Propagation-Society International Symposium (APSURSI) CY JUL 06-11, 2014 CL Memphis, TN SP Inst Elect Elect Engineers, Inst Elect Elect Engineers Antennas & Propagat Soc AB The electromagnetic scattering responses of nonlinearly loaded antenna structures excited by single-tone or multi-tone incident fields are considered in the frequency domain by employing a combination of the method-of-moments and a harmonic balance technique. Subsequently, standoff detection and localization of the scatterers in the presence of a half space is demonstrated with a subspace imaging procedure by exploiting the harmonic scattering responses. C1 US Army Res Lab, Adelphi, MD 20783 USA. RP Liao, DH (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. NR 4 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1522-3965 BN 978-1-4799-3540-6 J9 IEEE ANTENNAS PROP PY 2014 BP 135 EP 136 PG 2 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BD5LF UT WOS:000361554400068 ER PT S AU Martone, A Ranney, K AF Martone, Anthony Ranney, Kenneth GP IEEE TI Fast Technique for Wideband Spectrum Sensing SO 2014 IEEE ANTENNAS AND PROPAGATION SOCIETY INTERNATIONAL SYMPOSIUM (APSURSI) SE IEEE Antennas and Propagation Society International Symposium LA English DT Proceedings Paper CT IEEE Antennas-and-Propagation-Society International Symposium (APSURSI) CY JUL 06-11, 2014 CL Memphis, TN SP Inst Elect Elect Engineers, Inst Elect Elect Engineers Antennas & Propagat Soc AB The wideband spectrum sensing method described in this paper considers selecting unoccupied frequencies within a frequency band of interest. Two energy detection criteria are required to select an unoccupied frequency: 1) the energy of an unoccupied frequency must be below a predetermined threshold; 2) the sum of energy surrounding an unoccupied frequency must be below a predetermined threshold. The proposed method eliminates regions, or clusters, within the frequency band containing high energy. The accuracy and computational complexity of the proposed method is compared to a preexisting technique. C1 [Martone, Anthony; Ranney, Kenneth] US Army Res Lab, Adelphi, MD 20783 USA. RP Martone, A (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 5 TC 1 Z9 1 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1522-3965 BN 978-1-4799-3540-6 J9 IEEE ANTENNAS PROP PY 2014 BP 1206 EP 1207 PG 2 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BD5LF UT WOS:000361554401164 ER PT S AU Murray, BP Zaghloul, AI AF Murray, Bryan P. Zaghloul, Amir I. GP IEEE TI Self-Discovery and Orientation of a Randomly Distributed Cognitive Beamforming Array SO 2014 IEEE ANTENNAS AND PROPAGATION SOCIETY INTERNATIONAL SYMPOSIUM (APSURSI) SE IEEE Antennas and Propagation Society International Symposium LA English DT Proceedings Paper CT IEEE Antennas-and-Propagation-Society International Symposium (APSURSI) CY JUL 06-11, 2014 CL Memphis, TN SP Inst Elect Elect Engineers, Inst Elect Elect Engineers Antennas & Propagat Soc ID SENSOR NETWORKS AB This paper introduces the MARCO POLO Algorithm (MPA) that uses wireless discovery and control signals from a Master Control Node (MCN) with a cognitive engine to learn the relative location and orientation of a randomly distributed set of array elements. The elements are then synchronized and instructed to apply appropriate magnitude and phase offsets to collectively radiate as an array with beamforming capability. Unlike conventional discovery algorithms, MARCO POLO does not assume any a priori information about the array elements, does not rely on reference beacons, and works without GPS. With this algorithm, sensor nodes can be placed around the periphery of a complex enclosure, such as a vehicle, aircraft, or building and then self-organize into a distributed array with no wired connectivity. C1 [Murray, Bryan P.] Fed Bur Invest, Antenna Syst Dev Facil, Quantico, VA 22135 USA. [Murray, Bryan P.; Zaghloul, Amir I.] Virginia Tech, Blacksburg, VA 24061 USA. [Zaghloul, Amir I.] US Army Res Lab, Adelphi, MD 20783 USA. RP Murray, BP (reprint author), Fed Bur Invest, Antenna Syst Dev Facil, Quantico, VA 22135 USA. EM bryan.murray@ic.fbi.gov; amirz@vt.edu NR 10 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1522-3965 BN 978-1-4799-3540-6 J9 IEEE ANTENNAS PROP PY 2014 BP 1208 EP 1209 PG 2 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BD5LF UT WOS:000361554401165 ER PT S AU Anthony, TK Zaghloul, AI AF Anthony, Theodore K. Zaghloul, Amir I. GP IEEE TI Matching Two-Arm Spiral Impedance without Balun SO 2014 IEEE ANTENNAS AND PROPAGATION SOCIETY INTERNATIONAL SYMPOSIUM (APSURSI) SE IEEE Antennas and Propagation Society International Symposium LA English DT Proceedings Paper CT IEEE Antennas-and-Propagation-Society International Symposium (APSURSI) CY JUL 06-11, 2014 CL Memphis, TN SP Inst Elect Elect Engineers, Inst Elect Elect Engineers Antennas & Propagat Soc ID ANTENNA AB Spiral antennas can be designed to cover decades of bandwidth (e.g. 350-8350 MHz). Connecting the antenna directly to the coaxial cable without a balun would reduce fabrication costs without sacrificing realized gain. This paper shows how two-arm spiral antennas can be designed to have a broadband impedance close to 50 Ohms, rather than the traditional 180 Ohms, without the need to make and attach a balun. C1 [Anthony, Theodore K.; Zaghloul, Amir I.] US Army Res Lab, Adelphi, MD 20783 USA. RP Anthony, TK (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. EM theodore.k.anthony.civ@mail.mil; amir.i.zaghloul.civ@mail.mil NR 7 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1522-3965 BN 978-1-4799-3540-6 J9 IEEE ANTENNAS PROP PY 2014 BP 1325 EP 1326 PG 2 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BD5LF UT WOS:000361554401221 ER PT S AU Hodge, JA Anthony, T Zaghloul, AI AF Hodge, John A. Anthony, Theodore Zaghloul, Amir I. GP IEEE TI Enhancement of the Dipole Antenna Using a Capcitively Loaded Loop (CLL) Structure SO 2014 IEEE ANTENNAS AND PROPAGATION SOCIETY INTERNATIONAL SYMPOSIUM (APSURSI) SE IEEE Antennas and Propagation Society International Symposium LA English DT Proceedings Paper CT IEEE Antennas-and-Propagation-Society International Symposium (APSURSI) CY JUL 06-11, 2014 CL Memphis, TN SP Inst Elect Elect Engineers, Inst Elect Elect Engineers Antennas & Propagat Soc ID ARTIFICIAL MAGNETIC CONDUCTOR; SURFACES AB Recently, metamaterials have become a research topic of considerable interest, because these artificially constructed materials allow for the realization of exotic electromagnetic properties not found in conventional materials. This paper introduces a novel antenna enhancing structure consisting of capacitively loaded loop (CLL) metamaterial elements placed radially around a standard dipole antenna at an electrically small distance. As a result of this novel arrangement, the dipole antenna is easily transformed into a directive mechanically scanned antenna with high realized gain. The desired directivity and gain can be tuned based on the number of radial CLL fins placed around the dipole. Interactions between the antenna and metamaterial elements result in significant enhancement of the maximum radiated field amplitude and front-to-back ratio. The structures presented are modeled using full-wave simulation and one is experimentally verified as a proof-of-concept. C1 [Hodge, John A.; Zaghloul, Amir I.] Virginia Tech, Bradley Dept Elect & Comp Engn, Blacksburg, VA 24061 USA. [Anthony, Theodore; Zaghloul, Amir I.] US Army Res Lab, Adelphi, MD 20783 USA. RP Hodge, JA (reprint author), Virginia Tech, Bradley Dept Elect & Comp Engn, Blacksburg, VA 24061 USA. NR 7 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1522-3965 BN 978-1-4799-3540-6 J9 IEEE ANTENNAS PROP PY 2014 BP 1544 EP 1545 PG 2 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BD5LF UT WOS:000361554401326 ER PT S AU Palreddy, S Zaghloul, AI AF Palreddy, Sandeep Zaghloul, Amir I. GP IEEE TI Transmission Line Analysis of Electromagnetic Band Gap (EBG) Structures SO 2014 IEEE ANTENNAS AND PROPAGATION SOCIETY INTERNATIONAL SYMPOSIUM (APSURSI) SE IEEE Antennas and Propagation Society International Symposium LA English DT Proceedings Paper CT IEEE Antennas-and-Propagation-Society International Symposium (APSURSI) CY JUL 06-11, 2014 CL Memphis, TN SP Inst Elect Elect Engineers, Inst Elect Elect Engineers Antennas & Propagat Soc AB This paper presents transmission line analysis of electromagnetic band gap (EBG) structures, using ABCD matrices, and derives the required condition for the EBG resonance. This analysis can be applied to both regular uniform EBG structures and stacked EBG structures. The analysis assumes normal plane wave incidence and uses transmission line theory to calculate the surface impedance of the EBG structure and calculates the required condition. C1 [Palreddy, Sandeep; Zaghloul, Amir I.] Virginia Tech, Falls Church, VA 22043 USA. [Palreddy, Sandeep] Microwave Engn Corp, N Andover, MA 01845 USA. [Zaghloul, Amir I.] US Army Res Lab, Adelphi, MD 20783 USA. RP Palreddy, S (reprint author), Virginia Tech, Falls Church, VA 22043 USA. EM sandeep.palreddy@gmail.com; amirz@vt.edu NR 4 TC 1 Z9 1 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1522-3965 BN 978-1-4799-3540-6 J9 IEEE ANTENNAS PROP PY 2014 BP 1556 EP 1557 PG 2 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BD5LF UT WOS:000361554401332 ER PT S AU Darwish, AM Ibrahim, AA Qiu, J Viveiros, E Hung, HA AF Darwish, Ali M. Ibrahim, Amr A. Qiu, Joe Viveiros, Edward Hung, H. Alfred GP IEEE TI Novel Ka-Band 'Offset-Divider/Combiner' with Reflection Cancellation SO 2014 IEEE MTT-S INTERNATIONAL MICROWAVE SYMPOSIUM (IMS) SE IEEE MTT-S International Microwave Symposium LA English DT Proceedings Paper CT IEEE MTT-S International Microwave Symposium (IMS) CY JUN 01-06, 2014 CL Tampa, FL SP IEEE MTT S ID DESIGN AB A novel power divider/combiner concept is presented and demonstrated at Ka-band. The new offset-divider/combiner concept provides reflection cancelation, and 1-to-N or N:/1 (arbitrary N, including odd numbers) splitting or summing with equal or unequal power division/summation. Additionally, it has inherently low loss due to its use of low impedance transmission lines. It can be implemented in most technologies (microstrip, CPW, stripline, waveguide, etc.). In this paper, the new concept is demonstrated with a 27-33 GHz divider/combiner using microstrip technology. The bandwidth can be easily expanded to cover an octave. C1 [Darwish, Ali M.; Ibrahim, Amr A.] Amer Univ Cairo, Cairo 11835, Egypt. [Qiu, Joe; Viveiros, Edward; Hung, H. Alfred] Army Res Lab, Adelphi, MD 20783 USA. RP Darwish, AM (reprint author), Army Res Lab, Adelphi, MD 20783 USA. EM darwish@alum.mit.edu; amralaa87@gmail.com; hahung@alum.mit.edu NR 8 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 0149-645X BN 978-1-4799-3869-8 J9 IEEE MTT S INT MICR PY 2014 PG 3 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA BD7MH UT WOS:000363283700275 ER PT S AU Enserink, S Fitz, MP Goverdhanam, K Gu, CY Halford, TR Hossain, I Karawas, G Takeshita, OY AF Enserink, Scott Fitz, Michael P. Goverdhanam, Kavita Gu, Changyi Halford, Thomas R. Hossain, Iftekhar Karawas, Georg Takeshita, Oscar Y. GP IEEE TI Joint Analog and Digital Interference Cancellation SO 2014 IEEE MTT-S INTERNATIONAL MICROWAVE SYMPOSIUM (IMS) SE IEEE MTT-S International Microwave Symposium LA English DT Proceedings Paper CT IEEE MTT-S International Microwave Symposium (IMS) CY JUN 01-06, 2014 CL Tampa, FL SP IEEE MTT S DE Adaptive cancellation; full-duplex wireless; interference cancellation; interference mitigation AB The mitigation of in-band interference from co-located emitters is an increasingly important problem in commercial and military wireless communications systems design. In this work, we present a co-located interference mitigation approach that is targeted for scenarios in which the interfering signal is received at an extremely high power and the delay between the received (over-the-air) and reference (wired) copies of the interferer is not negligible. Such scenarios are common in military applications (e.g., simultaneous jamming and communications). The proposed Joint Analog and Digital Interference Cancellation (JADIC) system is self-configuring and can provide over 100 dB of suppression of wide band and narrowband jammers. C1 [Enserink, Scott; Fitz, Michael P.; Gu, Changyi; Halford, Thomas R.; Takeshita, Oscar Y.] TrellisWare Technol Inc, San Diego, CA 92127 USA. [Goverdhanam, Kavita; Hossain, Iftekhar; Karawas, Georg] US Army, CERDEC S&TCD, EMI Mitigat & Mat Res Branch, Aberdeen Proving Ground, MD 21005 USA. RP Enserink, S (reprint author), TrellisWare Technol Inc, 16516 Via Esprillo,Suite 300, San Diego, CA 92127 USA. NR 7 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 0149-645X BN 978-1-4799-3869-8 J9 IEEE MTT S INT MICR PY 2014 PG 3 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA BD7MH UT WOS:000363283700253 ER PT B AU Harris, JT Segall, AE Robinson, D Carter, R AF Harris, J. T. Segall, A. E. Robinson, D. Carter, R. BE Krishnamurthy, S TI Interfacial Blister Evolution of Coated Surfaces under Severe Thermal and Pressure Transients SO PROCEEDINGS OF THE ASME PRESSURE VESSELS AND PIPING CONFERENCE - 2013, VOL 3: DESIGN AND ANALYSIS LA English DT Proceedings Paper CT ASME Pressure Vessels and Piping Conference (PVP-2013) CY JUL 14-18, 2013 CL Paris, FRANCE SP ASME, Pressure Vessels & Pip Div DE Transient; Thermal-Stress and -Strain; Cylinder; Cohesive Zone; Gun Barrel ID BARRIER COATINGS; THERMOMECHANICAL CRACKING; MECHANISMS; DAMAGE; DELAMINATION; SUBSTRATE; EROSION AB The effects of severe thermal- and pressure-transients on coated substrates with indentation-induced, blister defects were analyzed using experimental and finite-element methods. An explicit FEA approach was first used to assess the transient thermal- and stress-states and the propensity for fracture related damage and evolution, under uniform convection and pressure transients across the surface; cohesive zone properties were evaluated in a previous study before being applied in an implicit indentation simulation. The indentation simulation results then served as the initial conditions for explicit modeling of interfacial flaw evolution due to thermal and pressure transients. Various conditions were analyzed including thermal and gun tube boundary conditions, and the effects of coating thermal capacitance. Given the need for robust coatings, the experimental and modeling procedures explored by this study will have important ramifications for coated tube design. C1 [Harris, J. T.; Segall, A. E.; Robinson, D.] Penn State Univ, Engn Sci & Mech, University Pk, PA 16803 USA. [Carter, R.] US Army Res Lab, AMSRL WM MB, Aberdeen Proving Ground, MD 21005 USA. RP Harris, JT (reprint author), Penn State Univ, Engn Sci & Mech, 212 EES Bldg, University Pk, PA 16803 USA. EM jth203@psu.edu; aesegall@psu.edu; rcarter@arl.army.mil NR 23 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5567-6 PY 2014 AR UNSP V003T03A109 PG 15 WC Engineering, Industrial; Engineering, Mechanical SC Engineering GA BD7CA UT WOS:000362862200109 ER PT B AU Rusnak, JM Smith, LA AF Rusnak, Janice M. Smith, Leonard A. BE Liu, D TI Botulinum Neurotoxins from Clostridium botulinum SO MANUAL OF SECURITY SENSITIVE MICROBES AND TOXINS LA English DT Article; Book Chapter ID LINKED-IMMUNOSORBENT-ASSAY; BLACK TAR HEROIN; REAL-TIME PCR; TOXIN TYPE-A; INTESTINAL TOXEMIA BOTULISM; COLORIMETRIC CAPTURE ELISAS; INJECTING DRUG-USERS; BUTYRICUM TYPE-E; INFANT BOTULISM; WOUND BOTULISM C1 [Rusnak, Janice M.] Goldbeltraven LLC, Ft Detrick, MD 21701 USA. [Smith, Leonard A.] US Army, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA. RP Rusnak, JM (reprint author), Goldbeltraven LLC, Ft Detrick, MD 21701 USA. NR 212 TC 0 Z9 0 U1 2 U2 4 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-5398-9; 978-1-4665-5396-5 PY 2014 BP 451 EP 466 D2 10.1201/b16752 PG 16 WC Infectious Diseases; Microbiology; Toxicology SC Infectious Diseases; Microbiology; Toxicology GA BD7GW UT WOS:000363061700041 ER PT B AU Bingham, JP Likeman, RK Hawley, JS Yu, PYC Halford, ZA AF Bingham, Jon-Paul Likeman, Robert K. Hawley, Joshua S. Yu, Peter Y. C. Halford, Zan A. BE Liu, D TI Conotoxins SO MANUAL OF SECURITY SENSITIVE MICROBES AND TOXINS LA English DT Article; Book Chapter ID NICOTINIC ACETYLCHOLINE-RECEPTOR; GATED SODIUM-CHANNELS; CONUS-PURPURASCENS VENOM; ALPHA-CONOTOXIN; ION-CHANNEL; MU-CONOTOXINS; NOREPINEPHRINE TRANSPORTER; 3-DIMENSIONAL STRUCTURE; EXCITATORY CONOTOXINS; BIOLOGICAL-ACTIVITY C1 [Bingham, Jon-Paul; Yu, Peter Y. C.; Halford, Zan A.] Univ Hawaii, Dept Mol Biosci & Bioengn, Honolulu, HI 96822 USA. [Likeman, Robert K.] Dept Def, Canberra, ACT, Australia. [Hawley, Joshua S.] Tripler Army Med Ctr, Dept Med, Honolulu, HI 96859 USA. RP Bingham, JP (reprint author), Univ Hawaii, Dept Mol Biosci & Bioengn, Honolulu, HI 96822 USA. NR 144 TC 0 Z9 0 U1 1 U2 1 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-5398-9; 978-1-4665-5396-5 PY 2014 BP 467 EP 484 D2 10.1201/b16752 PG 18 WC Infectious Diseases; Microbiology; Toxicology SC Infectious Diseases; Microbiology; Toxicology GA BD7GW UT WOS:000363061700042 ER PT B AU Heyn, T Mazhar, H Pazouki, A Melanz, D Seidl, A Madsen, J Bartholomew, A Negrut, D Lamb, D Tasora, A AF Heyn, Toby Mazhar, Hammad Pazouki, Arman Melanz, Daniel Seidl, Andrew Madsen, Justin Bartholomew, Aaron Negrut, Dan Lamb, David Tasora, Alessandro GP ASME TI CHRONO: A PARALLEL PHYSICS LIBRARY FOR RIGID-BODY, FLEXIBLE-BODY, AND FLUID DYNAMICS SO PROCEEDINGS OF THE ASME INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, 2013, VOL 7B LA English DT Proceedings Paper CT ASME International Design Engineering Technical Conferences / Computers and Information in Engineering Conference (IDETC/CIE) CY AUG 04-07, 2013 CL Portland, OR SP ASME, Design Engn Div, ASME, Comp & Informat Engn Div AB This contribution discusses a multi-physics simulation engine, called Chrono, that relies heavily on parallel computing. Chrono aims at simulating the dynamics of systems containing rigid bodies, flexible (compliant) bodies, and fluid-rigid body interaction. To this end, it relies on five modules: equation formulation (modeling), equation solution (simulation), collision detection support, domain decomposition for parallel computing, and post-processing analysis with emphasis on high quality rendering/visualization. For each component we point out how parallel CPU and/or GPU computing have been leveraged to allow for the simulation of applications with millions of degrees of freedom such as rover dynamics on granular terrain, fluid-structure interaction problems, or large-scale flexible body dynamics with friction and contact for applications in polymer analysis. C1 [Heyn, Toby; Mazhar, Hammad; Pazouki, Arman; Melanz, Daniel; Seidl, Andrew; Madsen, Justin; Bartholomew, Aaron; Negrut, Dan] Univ Wisconsin, Dept Mech Engn, Simulat Based Engn Lab, Madison, WI 53706 USA. [Lamb, David] US Army TARDEC, Warren, MI 48397 USA. [Tasora, Alessandro] Univ Parma, Dept Ind Engn, I-43100 Parma, Italy. RP Heyn, T (reprint author), Univ Wisconsin, Dept Mech Engn, Simulat Based Engn Lab, Madison, WI 53706 USA. EM heyn@wisc.edu; david.lamb@us.army.mil; tasora@ied.unipr.it NR 14 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5597-3 PY 2014 AR UNSP V07BT10A050 PG 6 WC Automation & Control Systems; Engineering, Mechanical; Operations Research & Management Science SC Automation & Control Systems; Engineering; Operations Research & Management Science GA BD6ZU UT WOS:000362796000050 ER PT B AU Schoepp, RJ Olinger, GG AF Schoepp, Randal J. Olinger, Gene G. BE Liu, D TI Filoviruses SO MANUAL OF SECURITY SENSITIVE MICROBES AND TOXINS LA English DT Article; Book Chapter ID EBOLA HEMORRHAGIC-FEVER; MARBURG-VIRUS-DISEASE; SUBTYPE RESTON VIRUS; BIOLOGICAL WEAPONS; RHESUS MACAQUES; EXPERIMENTAL-INFECTION; NUCLEOCAPSID PROTEINS; FAMILY FILOVIRIDAE; NONHUMAN-PRIMATES; SOUTHERN-AFRICA C1 [Schoepp, Randal J.] US Army, Diagnost Syst Div, Med Res Inst Infect Dis, Ft Detrick, MD 48231 USA. [Olinger, Gene G.] US Army, Div Virol, Med Res Inst Infect Dis, Ft Detrick, MD USA. RP Schoepp, RJ (reprint author), US Army, Diagnost Syst Div, Med Res Inst Infect Dis, Ft Detrick, MD 48231 USA. NR 150 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-5398-9; 978-1-4665-5396-5 PY 2014 BP 65 EP 80 D2 10.1201/b16752 PG 16 WC Infectious Diseases; Microbiology; Toxicology SC Infectious Diseases; Microbiology; Toxicology GA BD7GW UT WOS:000363061700008 ER PT B AU Drignei, D Mourelatos, ZP Pandey, V Kokkolaras, M Gorsich, D AF Drignei, Dorin Mourelatos, Zissimos P. Pandey, Vijitashwa Kokkolaras, Michael Gorsich, David GP ASME TI Accounting for Test Variability through Sizing Local Domains in Sequential Design Optimization with Concurrent Calibration-Based Model Validation SO PROCEEDINGS OF THE ASME INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, 2013, VOL 3B LA English DT Proceedings Paper CT ASME International Design Engineering Technical Conferences / Computers and Information in Engineering Conference (IDETC/CIE) CY AUG 04-07, 2013 CL Portland, OR SP ASME, Design Engn Div, ASME, Comp & Informat Engn Div ID COMPUTER EXPERIMENTS; PREDICTION AB We have recently proposed a new method for combined design optimization and calibration-based validation using a sequential approach with variable-size local domains of the design space and statistical bootstrap techniques. Our work was motivated by the fact that model validation in the entire design space may be neither affordable nor necessary. The method proceeds iteratively by obtaining test data at a design point, constructing around it a local domain in which the model is considered valid, and optimizing the design within this local domain. Due to test variability, it is important to know how many tests are needed to size each local domain of the sequential optimization process. Conducting an unnecessarily large number of tests may be inefficient, while a small number of tests may be insufficient to achieve the desired validity level. In this paper, we introduce a technique to determine the number of tests required to account for their variability by sizing the local domains accordingly. The goal is to achieve a desired level of model validation in each domain using the correlation between model data at the center and any other point in the local domain. The proposed technique is illustrated by means of a piston design example. C1 [Drignei, Dorin] Oakland Univ, Dept Math & Stat, Rochester, MI 48309 USA. [Mourelatos, Zissimos P.; Pandey, Vijitashwa] Oakland Univ, Dept Mech Engn, Rochester, MI 48309 USA. [Kokkolaras, Michael] McGill Univ, Dept Mech Engn, Montreal, PQ H3A 0C3, Canada. [Gorsich, David] US Army TARDEC, Ground Vehicle Syst, Warren, MI 48397 USA. RP Mourelatos, ZP (reprint author), Oakland Univ, Dept Math & Stat, Rochester, MI 48309 USA. EM mourelat@oakland.edu NR 14 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5589-8 PY 2014 AR V03BT03A049 PG 12 WC Engineering, Industrial; Engineering, Manufacturing; Engineering, Mechanical; Operations Research & Management Science SC Engineering; Operations Research & Management Science GA BD6MJ UT WOS:000362380400049 ER PT B AU Pandey, V Skowronska, AG Mourelatos, ZP Gorsich, D Castanier, M AF Pandey, Vijitashwa Skowronska, Annette G. Mourelatos, Zissimos P. Gorsich, David Castanier, Matthew GP ASME TI RELIABILITY AND FUNCTIONALITY OF REPAIRABLE SYSTEMS USING A MINIMAL SET OF METRICS: DESIGN AND MAINTENANCE OF A SMART CHARGING MICROGRID SO PROCEEDINGS OF THE ASME INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, 2013, VOL 3B LA English DT Proceedings Paper CT ASME International Design Engineering Technical Conferences / Computers and Information in Engineering Conference (IDETC/CIE) CY AUG 04-07, 2013 CL Portland, OR SP ASME, Design Engn Div, ASME, Comp & Informat Engn Div AB The definition of reliability may not be readily applicable for repairable systems. Our recent work has shown that multiple metrics are needed to fully account for the performance of a repairable system under uncertainty. Optimal tradeoffs among a minimal set of metrics can be used in the design and maintenance of these systems. A minimal set of metrics provides the most information about the system with the smallest number of metrics using a set of desirable properties. Critical installations such as a remote microgrid powering a military installation require a careful consideration of cost and repair strategies. This is because of logistical challenges in performing repairs and supplying necessary spare parts, particularly in unsafe locations. This paper shows how a minimal set of metrics enhances decision making in such a scenario. It enables optimal tradeoffs between critical attributes in decision making, while guaranteeing that all important performance measures are satisfied. As a result, cost targets and inventory planning can be achieved in an optimal way. We demonstrate the value of the proposed approach using a US Army smart-charging microgrid installation. C1 [Pandey, Vijitashwa; Mourelatos, Zissimos P.] Oakland Univ, Dept Mech Engn, Rochester, MI 48309 USA. [Skowronska, Annette G.; Gorsich, David; Castanier, Matthew] US Army TARDEC, Warren, MI 48397 USA. RP Pandey, V (reprint author), Oakland Univ, Dept Mech Engn, 2200 N Squirrel Rd, Rochester, MI 48309 USA. EM pandey2@oakland.edu; annette.g.skowronska.civ@mail.mil; mourelat@oakland.edu; david.j.gorsich.civ@mail.mil; matthew.p.castanier.civ@mail.mil NR 9 TC 0 Z9 0 U1 0 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5589-8 PY 2014 AR V03BT03A050 PG 9 WC Engineering, Industrial; Engineering, Manufacturing; Engineering, Mechanical; Operations Research & Management Science SC Engineering; Operations Research & Management Science GA BD6MJ UT WOS:000362380400050 ER PT B AU Ames, EC Pulikollu, RV AF Ames, Eric C. Pulikollu, Raja V. GP ASME TI VIRTUAL LIFE AND PERFORMANCE MODELING OF AEROSPACE SPIRAL BEVEL GEARS SO PROCEEDINGS OF THE ASME INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, 2013, VOL 5 LA English DT Proceedings Paper CT ASME International Design Engineering Technical Conferences / Computers and Information in Engineering Conference (IDETC/CIE) CY AUG 04-07, 2013 CL Portland, OR SP ASME, Design Engn Div, ASME, Comp & Informat Engn Div AB Spiral bevel gears are widely used in the tail rotor drive trains of most rotorcraft. The loads associated with the tail rotor drive train are generally much more variable than those in the main rotor drive train primarily resulting from maneuvers. Over the life of any particular military rotorcraft it is not uncommon for the aircraft's operating gross weight to steadily increase, causing the aircraft to fly at higher mean power levels and thus increasing the operating load spectrum associated with the tail rotor drive train. Special missions and equipment such as pulling a mine sweeping sled or very high altitude high gross weight assaults can put severe load demands on the tail drive train. This paper details an effort conducted to evaluate the effects of short to moderate duration overloads on the spiral bevel gears of the UH-60 helicopter tail rotor drive train. The focus of the effort was on the Tail Take-off gear mesh (TTO). An initial analytical assessment of the effect of loads above the endurance limit was conducted using an American Gear Manufacturers Association (AGMA) based approach. To confirm the validity of this approach, overload testing of the TTO gear mesh was conducted by the U.S. Army's Aviation Applied Technology Directorate at the Navy's test facility in Paxtuent River MD. Following the testing, the gear tooth bending and surface fatigue lives were analyzed using a microstructure based probabilistic tool developed by Sentient Corporation. The tool, known as Digital Clone was able to run hundreds of virtual tests that closely simulated the actual testing thus providing a low cost method for increasing the confidence associated with the effects of short to moderate high transient loads. C1 [Ames, Eric C.] US Army Res Dev & Engn Command, Ft Eustis, VA 23604 USA. [Pulikollu, Raja V.] Sentient Sci Corp, Idaho Falls, ID USA. RP Ames, EC (reprint author), US Army Res Dev & Engn Command, Ft Eustis, VA 23604 USA. NR 3 TC 0 Z9 0 U1 1 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5592-8 PY 2014 PG 8 WC Engineering, Industrial; Engineering, Mechanical SC Engineering GA BD6ML UT WOS:000362381000047 ER PT B AU Hood, A LaBerge, K Lewicki, D Pines, D AF Hood, Adrian LaBerge, Kelsen Lewicki, David Pines, Darryll GP ASME TI VIBRATION BASED SUN GEAR DAMAGE DETECTION SO PROCEEDINGS OF THE ASME INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, 2013, VOL 5 LA English DT Proceedings Paper CT ASME International Design Engineering Technical Conferences / Computers and Information in Engineering Conference (IDETC/CIE) CY AUG 04-07, 2013 CL Portland, OR SP ASME, Design Engn Div, ASME, Comp & Informat Engn Div AB Seeded fault experiments were conducted on the planetary stage of an OH-58C helicopter transmission. Two vibration based methods are discussed that isolate the dynamics of the sun gear from that of the planet gears, bearings, input spiral bevel stage, and other components in and around the gearbox. Three damaged sun gears: two spalled and one cracked, serve as the focus of this current work. A non-sequential vibration separation algorithm was developed and the resulting signals analyzed. The second method uses only the time synchronously averaged data but takes advantage of the signal/source mapping required for vibration separation. Both algorithms were successful in identifying the spall damage. Sun gear damage was confirmed by the presence of sun mesh groups. The sun tooth crack condition was inconclusive. C1 [Hood, Adrian; LaBerge, Kelsen] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. [Lewicki, David] NASA, Glenn Res Ctr, Cleveland, OH USA. [Pines, Darryll] Univ Maryland, A James Clark Sch Engn, College Pk, MD 20742 USA. RP Hood, A (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. EM adrian.a.hood@us.army.mil NR 38 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5592-8 PY 2014 AR V005T11A033 PG 14 WC Engineering, Industrial; Engineering, Mechanical SC Engineering GA BD6ML UT WOS:000362381000077 ER PT B AU Baechle, DM Wetzel, ED Agrawal, SK AF Baechle, Daniel M. Wetzel, Eric D. Agrawal, Sunil K. GP ASME TI DESIGN AND FABRICATION OF AN ARM EXOSKELETON FOR AIM STABILIZATION SO PROCEEDINGS OF THE ASME INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, 2013, VOL 6A LA English DT Proceedings Paper CT ASME International Design Engineering Technical Conferences / Computers and Information in Engineering Conference (IDETC/CIE) CY AUG 04-07, 2013 CL Portland, OR SP ASME, Design Engn Div, ASME, Comp & Informat Engn Div ID SHOOTING PERFORMANCE; TREMOR-SUPPRESSION; SHOOTERS; TIME AB Accurately aiming and firing a pistol requires a steady hand. While many devices can steady a shooter's arm or hand by restricting movement or degrees-of-freedom, few devices actively reduce involuntary tremors while allowing larger voluntary aiming movements. This paper details the design and fabrication of an arm exoskeleton that can actively damp arm tremors while allowing voluntary aiming movements. The device allows five degrees-of-freedom and is very lightweight due to its cable-driven architecture and use of carbon fiber composite materials. Tremorous movement is filtered out from voluntary motion, and an adaptive algorithm provides a tremor-cancelling signal to the cable control motors. C1 [Baechle, Daniel M.; Wetzel, Eric D.] US Army Res Lab, Aberdeen Proving Ground, MD USA. [Agrawal, Sunil K.] Columbia Univ, New York, NY 10027 USA. RP Agrawal, SK (reprint author), Columbia Univ, Mech Engn, New York, NY 10027 USA. EM Sunil.Agrawal@columbia.edu NR 15 TC 0 Z9 0 U1 1 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5593-5 PY 2014 AR V06AT07A074 PG 7 WC Engineering, Mechanical; Robotics SC Engineering; Robotics GA BD6RP UT WOS:000362533000074 ER PT B AU Gray, JP Vantsevich, VV Overholt, JL AF Gray, Jeremy P. Vantsevich, Vladimir V. Overholt, Jim L. GP ASME TI INDICES AND COMPUTATIONAL STRATEGY FOR UNMANNED GROUND WHEELED VEHICLE MOBILITY ESTIMATION AND ENHANCEMENT SO PROCEEDINGS OF THE ASME INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, 2013, VOL 6A LA English DT Proceedings Paper CT ASME International Design Engineering Technical Conferences / Computers and Information in Engineering Conference (IDETC/CIE) CY AUG 04-07, 2013 CL Portland, OR SP ASME, Design Engn Div, ASME, Comp & Informat Engn Div ID ROAD FRICTION COEFFICIENT; TIRE AB The United States Army began developing Unmanned Ground Vehicles (UGV) in the early 1900's. Concurrently, researchers developed and enhanced passenger and commercial ground vehicles. Although significant progress has been made for improving vehicle mobility for all ground vehicles throughout the past century, mobility has lacked a concise mutually agreed definition and analytical standardized criteria. The implementations of improved technologies, such as vehicle traction control, stability control, and torque vectoring systems require researchers to take a step back and reevaluate mobility criteria. UGVs require additional enhancement to include on-line mobility estimation since the vehicle cannot predict nor anticipate terrain conditions on their own prior to the vehicle traversing those conditions. This paper analyzes methodologies researchers have employed for defining and improving vehicle mobility of wheeled vehicles. The analysis is done from a view point of concurrent mobility methodologies' enhancement and applicability to wheeled UGVs. This analysis is then used to develop off-line and on-line analytical criterion for mobility estimation, and to derive a strategy which can be applied to wheeled vehicles, both manned and unmanned. The on-line mobility estimation enables the UGV to make control changes as the events occur rather than after the event, causing the vehicle to then optimize its reaction to regain control. C1 [Gray, Jeremy P.; Overholt, Jim L.] US Army TARDEC, Warren, MI 48092 USA. [Vantsevich, Vladimir V.; Overholt, Jim L.] Univ Alabama Birmingham, Birmingham, AL USA. RP Gray, JP (reprint author), US Army TARDEC, Warren, MI 48092 USA. NR 44 TC 0 Z9 0 U1 1 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5593-5 PY 2014 AR V06AT07A068 PG 10 WC Engineering, Mechanical; Robotics SC Engineering; Robotics GA BD6RP UT WOS:000362533000068 ER PT B AU Gerdes, JW Roberts, L Barnett, E Kempny, J Perez-Rosado, A Bruck, HA Gupta, SK AF Gerdes, John W. Roberts, Luke Barnett, Eli Kempny, Johannes Perez-Rosado, Ariel Bruck, Hugh A. Gupta, Satyandra K. GP ASME TI WING PERFORMANCE CHARACTERIZATION FOR FLAPPING WING AIR VEHICLES SO PROCEEDINGS OF THE ASME INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, 2013, VOL 6B LA English DT Proceedings Paper CT ASME International Design Engineering Technical Conferences / Computers and Information in Engineering Conference (IDETC/CIE) CY AUG 04-07, 2013 CL Portland, OR SP ASME, Design Engn Div, ASME, Comp & Informat Engn Div ID MODEL; VALIDATION; FLIGHT AB Flapping wing air vehicles offer many useful flight characteristics due to their versatility, as proven by flying animals. Wing design significantly influences the performance. However designing successful wings presents significant challenges. Efficient matching of the drive motors to the flapping wings is necessary to overcome the highly constrained weight budget. Simulating detailed information about the force response due to flapping is challenging due to complex fluid-structural interactions of the wings resulting in non-linear force response to flapping motion. To overcome this challenge, we conducted an experimental study of flapping wings to provide detailed temporal force response data for flapping wings. A prototype was built by synthesizing lightweight manufacturing techniques with the results of the experimental study. Our experimental investigations enabled us to select the flapping angle range and flapping frequency. C1 [Gerdes, John W.] US Army, Res Lab, Aberdeen Proving Ground, MD 21005 USA. [Roberts, Luke; Barnett, Eli; Kempny, Johannes; Perez-Rosado, Ariel; Gupta, Satyandra K.] Univ Maryland, Dept Mech Engn, Adv Mfg Lab, College Pk, MD 20740 USA. [Bruck, Hugh A.] Univ Maryland, Dept Mech Engn, Multiscale Measurements Lab, College Pk, MD 20740 USA. [Gupta, Satyandra K.] Univ Maryland, Syst Res Inst, Adv Mfg Lab, College Pk, MD 20740 USA. RP Gerdes, JW (reprint author), US Army, Res Lab, Aberdeen Proving Ground, MD 21005 USA. NR 30 TC 0 Z9 0 U1 0 U2 2 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5594-2 PY 2014 AR V06BT07A004 PG 10 WC Engineering, Mechanical; Robotics SC Engineering; Robotics GA BD6RQ UT WOS:000362533100004 ER PT B AU Lee, Z Lowe, S Van Poppel, BP Benson, MJ St Leger, A AF Lee, Zachary Lowe, Shane Van Poppel, Bret P. Benson, Michael J. St Leger, Aaron GP ASME TI UPGRADING THE UNDERGRADUATE GAS TURBINE LAB SO PROCEEDINGS OF THE ASME TURBO EXPO: TURBINE TECHNICAL CONFERENCE AND EXPOSITION, 2014, VOL 6 LA English DT Proceedings Paper CT ASME Turbo Expo: Turbine Technical Conference and Exposition CY JUN 16-20, 2014 CL Dusseldorf, GERMANY SP Int Gas Turbine Inst AB A study of gas turbine engines is an important component of an integrated thermodynamics and fluid mechanics two-course sequence at the United States Military Academy (USMA). Owing to the ubiquity of gas turbines in military use, graduating cadets will encounter a variety of these engines throughout their military careers. Especially for this unique population, it is important for engineering students to be familiar with the operation and applications of gas turbines. Experimental analysis of a functional auxiliary power unit (APU) from an Army utility helicopter has been a key component of this block of instruction for several decades. As with all laboratory equipment, the APU has experienced intermittent maintenance issues, which occasionally render it unusable for the gas turbine laboratory in the course. Because of this, a very basic virtual laboratory was implemented which integrated video of the physical laboratory with key parameters and behind-the-screen data collection for use in engine analysis. A revitalized version of both the physical and virtual gas turbine laboratory experiences offered in the thermal-fluids course will include substantial improvements over the existing setup. The physical laboratory, which is centered on a refurbished APU from a medium-sized commercial aircraft, will continue to incorporate measurements of temperature and pressure throughout the combustion process, as well as fuel flow rate. In an improvement over the original laboratory setup, an orifice plate will be used to measure the flow rate of bleed air exiting the turbine, which had not previously been open during engine testing. Additionally, the air flow through the anti-surge valve was not metered in the original version of the physical laboratory. However, the anti-surge air flow can account for nearly 25% of the total air flow, and performance calculations in the physical laboratory will now account for this loss. The turbine output shaft will run a water-brake dynamometer. All instrumentation will be converted to digital signals and projected on a large screen outside the test area through a LabVIEW front panel. The virtual laboratory will include the same metering options as the operational APU. In addition, the virtual laboratory will include the option to alter engine operating parameters, such as inlet temperature and pressure or exhaust temperatures, and students may conduct broad parameter sweeps across ranges of possible inputs or desired outputs. These improvements will enable students to gain a deeper understanding of gas turbine operation and capabilities in practical applications. The improved laboratory will be implemented in Spring, 2014. C1 [Lee, Zachary; Van Poppel, Bret P.; Benson, Michael J.; St Leger, Aaron] US Mil Acad, West Point, NY 10996 USA. [Lowe, Shane] United States Army, Ft Benning, GA USA. RP Benson, MJ (reprint author), US Mil Acad, West Point, NY 10996 USA. EM michael.benson@usma.edu NR 14 TC 0 Z9 0 U1 0 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-4575-2 PY 2014 AR V006T08A004 PG 8 WC Automation & Control Systems; Education, Scientific Disciplines; Engineering, Mechanical; Materials Science, Multidisciplinary SC Automation & Control Systems; Education & Educational Research; Engineering; Materials Science GA BD6IJ UT WOS:000362239800054 ER PT S AU Ma, L He, T Leung, KK Swami, A Towsley, D AF Ma, Lian He, Ting Leung, Kin K. Swami, Ananthram Towsley, Don GP IEEE TI Monitor Placement for Maximal Identifiability in Network Tomography SO 2014 PROCEEDINGS IEEE INFOCOM SE IEEE INFOCOM LA English DT Proceedings Paper CT 33rd IEEE Annual Conference on Computer Communications (IEEE INFOCOM) CY APR 27-MAY 02, 2014 CL Toronto, CANADA SP IEEE ID INFERENCE; DELAY AB We investigate the problem of placing a given number of monitors in a communication network to identify the maximum number of link metrics from end-to-end measurements between monitors, assuming that link metrics are additive, and measurement paths cannot contain cycles. Motivated by our previous result that complete identification of all link metrics can require a large number of monitors, we focus on partial identification using a limited number of monitors. The basis to our solution is an efficient algorithm for determining all identifiable links for a given monitor placement. Based on this algorithm, we develop a polynomial-time greedy algorithm to incrementally place monitors such that each newly placed monitor maximizes the number of additional identifiable links. We prove that the proposed algorithm is optimal for 2-vertex-connected networks, and demonstrate that it is near-optimal for several real ISP topologies that are not 2-vertex-connected. Our solution provides a quantifiable tradeoff between level of identifiability and available monitor resources. C1 [Ma, Lian; Leung, Kin K.] Univ London Imperial Coll Sci Technol & Med, London, England. [He, Ting] IBM TJ Watson Res Ctr, Yorktown Hts, NY USA. [Swami, Ananthram] Army Res Lab, Adelphi, MD USA. [Towsley, Don] Univ Massachusetts, Amherst, MA 01003 USA. RP Ma, L (reprint author), Univ London Imperial Coll Sci Technol & Med, London, England. EM l.ma10@imperial.ac.uk; the@us.ibm.com; kin.leung@imperial.ac.uk; ananthram.swami.civ@mail.mil; towsley@cs.umass.edu NR 19 TC 2 Z9 2 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 0743-166X BN 978-1-4799-3360-0 J9 IEEE INFOCOM SER PY 2014 BP 1447 EP 1455 PG 9 WC Computer Science, Hardware & Architecture; Engineering, Electrical & Electronic; Telecommunications SC Computer Science; Engineering; Telecommunications GA BD5KX UT WOS:000361544200162 ER PT S AU Lu, Z Wang, WY Wang, C AF Lu, Zhuo Wang, Wenye Wang, Cliff GP IEEE TI How Can Botnets Cause Storms? Understanding the Evolution and Impact of Mobile Botnets SO 2014 PROCEEDINGS IEEE INFOCOM SE IEEE INFOCOM LA English DT Proceedings Paper CT 33rd IEEE Annual Conference on Computer Communications (IEEE INFOCOM) CY APR 27-MAY 02, 2014 CL Toronto, CANADA SP IEEE AB A botnet in mobile networks is a collection of compromised nodes due to mobile malware, which are able to perform coordinated attacks. Different from Internet botnets, mobile botnets do not need to propagate using centralized infrastructures, but can keep compromising vulnerable nodes in close proximity and evolving organically via data forwarding. Such a distributed mechanism relies heavily on node mobility as well as wireless links, therefore breaks down the underlying premise in existing epidemic modeling for Internet botnets. In this paper, we adopt a stochastic approach to study the evolution and impact of mobile botnets. We find that node mobility can be a trigger to botnet propagation storms: the average size (i.e., number of compromised nodes) of a botnet increases quadratically over time if the mobility range that each node can reach exceeds a threshold; otherwise, the botnet can only contaminate a limited number of nodes with average size always bounded above. This also reveals that mobile botnets can propagate at the fastest rate of quadratic growth in size, which is substantially slower than the exponential growth of Internet botnets. To measure the denial-of-service impact of a mobile botnet, we define a new metric, called last chipper time, which is the last time that service requests, even partially, can still be processed on time as the botnet keeps propagating and launching attacks. The last chipper time is identified to decrease at most on the order of 1/root B, where B is the network bandwidth. This result reveals that although increasing network bandwidth can help with mobile services; at the same time, it can indeed escalate the risk for services being disrupted by mobile botnets. C1 [Lu, Zhuo; Wang, Wenye] N Carolina State Univ, Dept Elect & Comp Engn, Raleigh, NC 27606 USA. [Wang, Cliff] Army Res Off, Res Triangle Pk, NC 27709 USA. RP Lu, Z (reprint author), N Carolina State Univ, Dept Elect & Comp Engn, Raleigh, NC 27606 USA. EM z1u3@ncsu.edu; wwang@ncsu.edu; cliff.wang@us.army.mil NR 27 TC 2 Z9 2 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 0743-166X BN 978-1-4799-3360-0 J9 IEEE INFOCOM SER PY 2014 BP 1501 EP 1509 PG 9 WC Computer Science, Hardware & Architecture; Engineering, Electrical & Electronic; Telecommunications SC Computer Science; Engineering; Telecommunications GA BD5KX UT WOS:000361544200168 ER PT S AU Nix, T Bettati, R AF Nix, Timothy Bettati, Riccardo BE Shakshuki, E Yasar, A TI Neighborhood Failures in Random Topology Covert Communication Networks SO 5TH INTERNATIONAL CONFERENCE ON AMBIENT SYSTEMS, NETWORKS AND TECHNOLOGIES (ANT-2014), THE 4TH INTERNATIONAL CONFERENCE ON SUSTAINABLE ENERGY INFORMATION TECHNOLOGY (SEIT-2014) SE Procedia Computer Science LA English DT Proceedings Paper CT 5th International Conference on Ambient Systems, Networks and Technologies (ANT) / 4th International Conference on Sustainable Energy Information Technology (SEIT) CY JUN 02-05, 2014 CL Hasselt, BELGIUM DE covert communication networks; anonymity networks; membership concealment; network topology; peer-to-peer networks AB A covert communications network is a connected, overlay, peer-to-peer network being used to support communications within a group in which the survival of the group depends on (a) confidentiality and anonymity for communications, (b) concealment of participation in the network to both other members of the group and external eavesdroppers, and (c) resilience against disconnection. These requirements are much more stringent than for typical privacy and anonymity systems. In order to protect the network from subversion of individual nodes, neighbors of failed nodes have to be isolated from the network as well. Thus, all failures have to treated as neighborhood failures. Network membership is protected through topology management in order to limit each participant's knowledge of the network addresses (IP address, email address, etc.) of other participants. In this paper, we propose a measure for determining the suitability of random topologies for use in a covert communication network, and we use this measure to analyze the suitability of Erdos-Renyi Random Graphs for use in a covert communication network. (C) 2014 Published by Elsevier B.V. C1 [Nix, Timothy] US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. [Bettati, Riccardo] Texas A&M Univ, Dept Comp Sci & Engn, College Stn, TX 77843 USA. RP Nix, T (reprint author), US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. EM timothy.nix@usma.edu NR 12 TC 1 Z9 1 U1 0 U2 0 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 1877-0509 J9 PROCEDIA COMPUT SCI PY 2014 VL 32 BP 1127 EP 1134 DI 10.1016/j.procs.2014.05.543 PG 8 WC Computer Science, Artificial Intelligence; Computer Science, Hardware & Architecture; Computer Science, Theory & Methods; Energy & Fuels SC Computer Science; Energy & Fuels GA BD5LN UT WOS:000361562600150 ER PT B AU Rudy, R Cohen, AJ Pulskamp, JS Polcawich, RG Oldham, KR AF Rudy, Ryan Cohen, Adam J. Pulskamp, Jeffrey S. Polcawich, Ronald G. Oldham, Kenn R. GP ASME TI ANTENNA-LIKE TACTILE SENSOR FOR THIN-FILM PIEZOELECTRIC MICROROBOTS SO PROCEEDINGS OF THE ASME INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, 2013, VOL 1 LA English DT Proceedings Paper CT ASME International Design Engineering Technical Conferences / Computers and Information in Engineering Conference (IDETC/CIE) CY AUG 04-07, 2013 CL Portland, OR SP ASME, Design Engn Div, ASME, Comp & Informat Engn Div ID FABRICATION; FORCE AB Terrestrial and other millimeter-scale autonomous micro-robots face significant challenges in surveying their environment, due to small power budgets and payload capacities. One low-power, low-mass form of obstacle detection is tactile sensing of contact with other surfaces. In this-paper, a tactile sensor inspired by insect antennae is described, based on thin-film lead-zirconate-titanate (PZT) transduction. Thin-film piezoelectric materials permit actuation and sensing mechanisms to be coupled in very small, compact structures, as well as complement previously developed micro-robotic leg mechanisms. Key design parameters for the tactile sensor are introduced and analyzed in terms of sweep frequency and range of motion, and signals from sensor impact are predicted. Experimental results with partially-released prototype actuators show respectable agreement with modeled behavior for dynamic motion, though impact detection is hampered by large feedthrough disturbances. Completed sensors range from 2 to 4 mm in length and are approximately 500 pm in width, with a sweep range of nearly 1 mm demonstrated from a 2 mm long prototype. C1 [Rudy, Ryan; Pulskamp, Jeffrey S.; Polcawich, Ronald G.] US Army Res Lab, Adelphi, MD 20783 USA. [Cohen, Adam J.; Oldham, Kenn R.] Univ Michigan, Ann Arbor, MI 48109 USA. RP Rudy, R (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. NR 12 TC 0 Z9 0 U1 1 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5584-3 PY 2014 AR V001T09A023 PG 7 WC Education, Scientific Disciplines; Engineering, Mechanical; Nanoscience & Nanotechnology; Transportation Science & Technology SC Education & Educational Research; Engineering; Science & Technology - Other Topics; Transportation GA BD6IM UT WOS:000362240300084 ER PT B AU Chao, NH DeAngelis, ME Lee, J Kleinbach, KS Cheng, RB AF Chao, Nien-Hua DeAngelis, Mario E. Lee, Jyeching Kleinbach, K. S. Cheng, Ron-Bin GP ASME TI ADVANCED MODELING FOR MINIATURIZED POTTED SMART MUNITIONS DEVELOPMENT SO PROCEEDINGS OF THE ASME INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, 2013, VOL 2A LA English DT Proceedings Paper CT ASME International Design Engineering Technical Conferences / Computers and Information in Engineering Conference (IDETC/CIE) CY AUG 04-07, 2013 CL Portland, OR SP ASME, Design Engn Div, ASME, Comp & Informat Engn Div AB Miniaturized electronics and components are becoming more common in precision-guided artillery-launched munitions and missiles. Due to the highly dynamic nature of projectile launch, and the demands for increased structural robustness, many miniaturized smart munitions resort to a potted design in order to achieve functionality and reliability requirements. In most of these applications, the potted electronics are inactive for most of their lifetime and may be stored without environmental (temperature and humidity) controls for up to 20 years. The uncontrolled environment for smart munitions however makes the thermal management task especially difficult due to the coefficient of thermal expansion (CTE) mismatch between the potting material and the electronic components. It has been previously observed that modeling a potted device, in support of its development through finite-element simulations, is a complex task due to the numerical-convergence issues, material properties and meshes, during simulations as well as resource limitations. In this paper, we will present a modeling/simulation methodology which can be used in the development of miniaturized potted smart munitions and the product qualification process. There are two basic tests that a potential new munition needs to satisfy: 1) a highly accelerated temperature-cycling life test (HALT), to emulate the un-controlled projectile storage environment and, 2) the extremely high-G acceleration during a projectile launch. In this paper, we will present, 1) the use of finite-element analysis to support design decisions to overcome the CTE differences between electronic components on the circuit board assembly and the potting material and, 2) the use of finite-element simulations to study and improve the survivability of the electronic components on the circuit board assembly during extremely high-G acceleration projectile launches. C1 [Chao, Nien-Hua; DeAngelis, Mario E.; Lee, Jyeching; Kleinbach, K. S.] US Army, ARDEC, Picatinny Arsenal, NJ 07885 USA. [Cheng, Ron-Bin] Dassault Syst Simulia Corp, Providence, RI USA. RP Chao, NH (reprint author), US Army, ARDEC, Picatinny Arsenal, NJ 07885 USA. NR 21 TC 0 Z9 0 U1 2 U2 2 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5585-0 PY 2014 AR V02AT02A020 PG 9 WC Computer Science, Interdisciplinary Applications; Engineering, Industrial; Engineering, Mechanical SC Computer Science; Engineering GA BD6IN UT WOS:000362241500020 ER PT B AU Altman, DH Gupta, A Dubrowski, TE Sharar, DJ Jankowski, NR North, MT AF Altman, David H. Gupta, Anurag Dubrowski, Thomas E., Jr. Sharar, Darin J. Jankowski, Nicholas R. North, Mark T. GP ASME TI ANALYSIS AND CHARACTERIZATION OF THERMAL EXPANSION-MATCHED WICK-BASED MULTI-CHIP PASSIVE HEAT SPREADERS IN STATIC AND DYNAMIC ENVIRONMENTS SO PROCEEDINGS OF THE ASME INTERNATIONAL TECHNICAL CONFERENCE AND EXHIBITION ON PACKAGING AND INTEGRATION OF ELECTRONIC AND PHOTONIC MICROSYSTEMS, 2013, VOL 2 LA English DT Proceedings Paper CT ASME International Technical Conference and Exhibition on Packaging and Integration of Electronic and Photonic Microsystems CY JUL 16-18, 2013 CL Burlingame, CA SP ASME, Elect & Photon Packag Div DE heat spreader; heat pipe; vapor chamber; thermal resistance; sintered powder wick; high-g environment AB Ensuring adequate spreading of heat dissipated by high power density devices is a critical part of many electronics packaging designs. In many cases, passive wick-based heat spreaders can offer improved heat spreading performance relative to solid conductor alternatives. However, concerns related to performance degradation in high-inertial force environments frequently limit their use to static or near-static applications. In this work we investigate the performance of low coefficient of thermal expansion (CTE) wick-based heat spreaders cooling multiple high heat flux devices in static and high-g environments. Two high-power devices are simulated using custom-manufactured resistor-thermometer chips, enabling dissipation of die average heat fluxes in excess of 150W/cm(2). Comparative thermal performance is evaluated for wick-based heat spreaders and solid CuMo heat spreaders of equivalent CTE affixed with interface materials typical of those used when attaching a low CTE package to a high CTE cold plate (e.g., Al or Cu). Thermal performance is characterized as a function of heat input during exposure to increasing g-forces applied using a custom-built centrifuge. Experimental observations are interpreted through detailed modeling of fluid flow patterns within the wick structure of the passive heat spreader. Results from these experiments demonstrate that properly designed wick-based heat spreaders have utility in both static and dynamic environments, exhibiting effective conductivities in excess of that obtainable with competitive low-expansion composites. C1 [Altman, David H.; Gupta, Anurag; Dubrowski, Thomas E., Jr.] Raytheon Integrated Def Syst, Sudbury, MA 01776 USA. [Sharar, Darin J.] Gen Tech Serv, Wall, NJ USA. [Jankowski, Nicholas R.] Army Res Lab, Adelphi, MD USA. [North, Mark T.] Thermacore Inc, Lancaster, PA USA. RP Altman, DH (reprint author), Raytheon Integrated Def Syst, Sudbury, MA 01776 USA. NR 14 TC 0 Z9 0 U1 1 U2 2 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5576-8 PY 2014 AR V002T08A018 PG 13 WC Thermodynamics; Engineering, Mechanical SC Thermodynamics; Engineering GA BD5JH UT WOS:000361499700018 ER PT B AU Sharar, DJ Jankowski, NR Bar-Cohen, A AF Sharar, Darin J. Jankowski, Nicholas R. Bar-Cohen, Avram GP ASME TI MODIFIED MODEL FOR IMPROVED FLOW REGIME PREDICTION IN INTERNALLY-GROOVED TUBES SO PROCEEDINGS OF THE ASME INTERNATIONAL TECHNICAL CONFERENCE AND EXHIBITION ON PACKAGING AND INTEGRATION OF ELECTRONIC AND PHOTONIC MICROSYSTEMS, 2013, VOL 2 LA English DT Proceedings Paper CT ASME International Technical Conference and Exhibition on Packaging and Integration of Electronic and Photonic Microsystems CY JUL 16-18, 2013 CL Burlingame, CA SP ASME, Elect & Photon Packag Div ID HORIZONTAL MICROFIN TUBES; EVAPORATION HEAT-TRANSFER; PATTERN MAP; SMOOTH; PIPE AB The absence. of phenomenological insights and accurate flow regime Models makes it difficult to predict the improved effectiveness of internally-grooved tubes for two-phase heat transfer. A re-interpretation of available data and flow regime maps is used to suggest that performance improvement is a result of early transition to Annular flow. A modified flow regime map, with a newly-developed Stratified-Wavy to Annular transition criteria for internally-grooved tubes, is shown to increase regime prediction accuracy by 27% relative to the traditional, smooth tube flow regime prediction. C1 [Sharar, Darin J.] Gen Tech Serv LLC, Wall, NJ USA. [Jankowski, Nicholas R.] US Army Res Lab, Adelphi, MD USA. [Bar-Cohen, Avram] Univ Maryland, College Pk, MD 20742 USA. RP Sharar, DJ (reprint author), Gen Tech Serv LLC, Wall, NJ USA. NR 29 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5576-8 PY 2014 AR V002T08A042 PG 9 WC Thermodynamics; Engineering, Mechanical SC Thermodynamics; Engineering GA BD5JH UT WOS:000361499700042 ER PT S AU Choi, M Kim, M Lee, T Chung, JM Garcia, RC AF Choi, Moonsuk Kim, Minseok Lee, Taejun Chung, Jong-Moon Garcia, Raymond C. GP IEEE TI Frequency Hopping Mobile Ad Hoc Network and Adjacent Channel Interference Implementation in NS-2 SO 18TH IEEE INTERNATIONAL SYMPOSIUM ON CONSUMER ELECTRONICS (ISCE 2014) SE IEEE International Symposium on Consumer Electronics LA English DT Proceedings Paper CT 18th IEEE International Symposium on Consumer Electronics (ISCE) CY JUN 22-25, 2014 CL SOUTH KOREA SP IEEE, IEIE DE Frequency hopping; ACI; MANET; NS-2 AB The event-driven network simulator NS-2 does not support frequency hopping (FH) and multi-channel operations, as well as the adjacent channel interference (ACI), in its current form. This paper introduces the key implementation methods to enable FH mobile ad hoc network (MANET) simulations in NS-2. The proposed simulator provides proper analysis in arbitrary topologies of FH-MANET. C1 [Choi, Moonsuk; Kim, Minseok; Lee, Taejun; Chung, Jong-Moon; Garcia, Raymond C.] Yonsei Univ, Sch Elect & Elect Engn, Seoul 120749, South Korea. [Garcia, Raymond C.] ICF Int, Army Res Lab, Adelphi, MD USA. RP Choi, M (reprint author), Yonsei Univ, Sch Elect & Elect Engn, Seoul 120749, South Korea. EM cms7@yonsei.ac.kr; msk84@yonsei.ac.kr; electronic@yonsei.ac.kr; jmc@yonsei.ac.kr; raymondgarcia@ieee.org NR 3 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2158-3994 J9 I SYMP CONSUM ELECTR PY 2014 PG 2 WC Engineering, Electrical & Electronic SC Engineering GA BD4RG UT WOS:000361020200255 ER PT S AU Garcia, RC Chung, JM Jo, SW Ha, T Kyong, T AF Garcia, Raymond C. Chung, Jong-Moon Jo, Sung-Woong Ha, Taeyoung Kyong, Taehyun GP IEEE TI Response Time Performance Estimation in Smartphones Applying Dynamic Voltage & Frequency Scaling and Completely Fair Scheduler SO 18TH IEEE INTERNATIONAL SYMPOSIUM ON CONSUMER ELECTRONICS (ISCE 2014) SE IEEE International Symposium on Consumer Electronics LA English DT Proceedings Paper CT 18th IEEE International Symposium on Consumer Electronics (ISCE) CY JUN 22-25, 2014 CL SOUTH KOREA SP IEEE, IEIE DE smartphone; response time; DVFS; CFS AB In this paper, a response time performance estimation scheme is proposed for smartphones applying dynamic voltage & frequency scaling (DVFS) at the central processing unit (CPU) and completely fair scheduler (CFS) at the Linux kernel. DVFS techniques influence the overall time performance of the smartphone since changes in CPU operational frequency will change all aspects of the CPUs responsiveness and access speed for task execution. CFS also has significant influence in task execution at the Linux kernel. Results show the effectiveness of the proposed scheme in estimating the instantaneous response time on a LG Optimus G smartphone. C1 [Garcia, Raymond C.] ICF Int, Army Res Lab, Adelphi, MD 20850 USA. [Garcia, Raymond C.; Chung, Jong-Moon; Jo, Sung-Woong; Ha, Taeyoung; Kyong, Taehyun] Yonsei Univ, Sch Elect & Elect Engn, Seoul 120749, South Korea. RP Garcia, RC (reprint author), ICF Int, Army Res Lab, Adelphi, MD 20850 USA. EM raymondgarcia@ieee.org; jmc@yonsei.ac.kr; cswo02@yonsei.ac.kr; taeyoungha@yonsei.ac.kr; nvidia@yonsei.ac.kr NR 9 TC 0 Z9 0 U1 4 U2 4 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2158-3994 J9 I SYMP CONSUM ELECTR PY 2014 PG 2 WC Engineering, Electrical & Electronic SC Engineering GA BD4RG UT WOS:000361020200206 ER PT B AU Liu, JC Jayakumar, P Stein, JL Ersal, T AF Liu, Jiechao Jayakumar, Paramsothy Stein, Jeffrey L. Ersal, Tulga GP ASME TI A MULTI-STAGE OPTIMIZATION FORMULATION FOR MPC-BASED OBSTACLE AVOIDANCE IN AUTONOMOUS VEHICLES USING A LIDAR SENSOR SO 7TH ANNUAL DYNAMIC SYSTEMS AND CONTROL CONFERENCE, 2014, VOL 2 LA English DT Proceedings Paper CT ASME 7th Annual Dynamic Systems and Control Conference CY OCT 22-24, 2014 CL San Antonio, TX SP ASME, Dynam Syst & Control Div ID MODEL-PREDICTIVE CONTROL; NAVIGATION AB The dynamics of an autonomous unmanned ground vehicle (UGV) that is at least the size of a passenger vehicle are critical to consider during obstacle avoidance maneuvers to ensure vehicle safety. Methods developed so far do not take vehicle dynamics and sensor limitations into account simultaneously and systematically to guarantee the vehicle's dynamical safety during avoidance maneuvers. To address this gap, this paper presents a model predictive control (MPC) based obstacle avoidance algorithm for high-speed, large-size UGVs that perceives the environment only through the information provided by a sensor, takes into account the sensing and control delays and the dynamic limitations of the vehicle, and provides smooth and continuous optimal solutions in terms of minimizing travel time. Specifically, information about the environment is obtained using an on-board Light Detection and Ranging (LIDAR) sensor. Ensuring the vehicle's dynamical safety is translated into avoiding single tire lift-off The obstacle avoidance problem is formulated as a multi-stage optimal control problem with a unique optimal solution. To solve the optimal control problem, it is transcribed into a nonlinear programming (NLP) problem using a pseudo-spectral method, and solved using the interior-point method. Sensing and control delays are explicitly taken into consideration in the formulation. Simulation results show that the algorithm is capable of generating smooth control commands to avoid obstacles while guaranteeing dynamical safety. C1 [Liu, Jiechao; Stein, Jeffrey L.; Ersal, Tulga] Univ Michigan, Dept Mech Engn, Ann Arbor, MI 48109 USA. [Jayakumar, Paramsothy] US Army RDECOM TARDEC, Warren, MI 48397 USA. RP Ersal, T (reprint author), Univ Michigan, Dept Mech Engn, Ann Arbor, MI 48109 USA. EM ljch@umich.edu; paramsothy.jayakumar.civ@mail.mil; stein@umich.edu; tersal@umich.edu NR 31 TC 0 Z9 0 U1 2 U2 2 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-4619-3 PY 2014 AR V002T30A006 PG 10 WC Automation & Control Systems; Engineering, Mechanical; Operations Research & Management Science SC Automation & Control Systems; Engineering; Operations Research & Management Science GA BD4XU UT WOS:000361166800071 ER PT B AU Vantsevich, VV Paldan, JR Gray, JP AF Vantsevich, Vladimir V. Paldan, Jesse R. Gray, Jeremy P. GP ASME TI A HYBRID-ELECTRIC POWER TRANSMITTING UNIT FOR 4X4 VEHICLE APPLICATIONS: MODELING AND SIMULATION SO 7TH ANNUAL DYNAMIC SYSTEMS AND CONTROL CONFERENCE, 2014, VOL 3 LA English DT Proceedings Paper CT ASME 7th Annual Dynamic Systems and Control Conference CT Research Workshop Israel Science Foundation on Infinite Products of Operators and their Applications CY OCT 22-24, 2014 CY MAY 21-24, 2012 CL San Antonio, TX CL Technion, Israel Inst Technol, Haifa, ISRAEL SP ASME, Dynam Syst & Control Div SP Technion, Ctr Math Sci HO Technion, Israel Inst Technol ID EDDY-CURRENT; BRAKE AB In this paper, a technical concept is described for a hybrid-electric power transmitting unit (HE-PTU) to control the split of power between the drive axles of a 4x4 hybrid-electric vehicle. This new power transmitting unit is a mechatronic systems by its design and uses a planetary gear set and eddy current brake to provide a continuously variable (dynamic) gear ratio that can be integrated into the vehicle driveline between the transfer case and front axle. The paper details the electrical and mechanical characteristics of the device, including its various operation modes, its mathematical model built from the equations of the planetary gear set and eddy current brake, an optimization condition by which the device will be controlled to improve vehicle energy efficiency, as well as its torque and electrical current usage. Computer simulations are performed on a mathematical model of a 4x4 military truck using the power transmitting unit in conjunction with a series hybrid-electric configuration transmission. C1 [Vantsevich, Vladimir V.; Paldan, Jesse R.] Univ Alabama Birmingham, Dept Mech Engn, Birmingham, AL 35233 USA. [Gray, Jeremy P.] US Army TARDEC, Warren, MI USA. RP Vantsevich, VV (reprint author), Univ Alabama Birmingham, Dept Mech Engn, Birmingham, AL 35233 USA. EM vantsevi@uab.edu; jpaldan@uab.edu; Jeremy.p.gray.civ@mail.mil NR 11 TC 0 Z9 0 U1 0 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-4620-9 PY 2014 AR V003T44A002 PG 10 WC Automation & Control Systems; Engineering, Mechanical; Operations Research & Management Science SC Automation & Control Systems; Engineering; Operations Research & Management Science GA BD4XX UT WOS:000361167200047 ER PT B AU Sibayan, JT AF Sibayan, Jerome Tan BE Youngman, PA Hadzikadic, M TI China's Complex Policy Network SO COMPLEXITY AND THE HUMAN EXPERIENCE: MODELING COMPLEXITY IN THE HUMANITIES AND SOCIAL SCIENCES LA English DT Article; Book Chapter C1 [Sibayan, Jerome Tan] US Army War Coll, Carlisle, PA 17013 USA. [Sibayan, Jerome Tan] Kansas State Univ, Secur Studies, Manhattan, KS 66506 USA. RP Sibayan, JT (reprint author), US Army War Coll, 122 Forbes Ave, Carlisle, PA 17013 USA. EM jerome.t.sibayan.mil@mail.mil NR 27 TC 0 Z9 0 U1 0 U2 1 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-981-4463-27-0; 978-981-4463-26-3 PY 2014 BP 161 EP 181 D2 10.1201/b16877 PG 21 WC Anthropology; Philosophy SC Anthropology; Philosophy GA BD3IF UT WOS:000359759900010 ER PT B AU Tamm, G Klosky, JL Baxter, J Grant, L Melnick, I Young, J AF Tamm, Gunnar Klosky, J. Ledlie Baxter, Jacob Grant, Luke Melnick, Isaac Young, Jacob GP ASME TI WASTE HEAT RECOVERY FROM GENERATORS IN THE DEPLOYED ARMY SO PROCEEDINGS OF THE ASME 8TH INTERNATIONAL CONFERENCE ON ENERGY SUSTAINABILITY, 2014, VOL 1 LA English DT Proceedings Paper CT ASME 8th International Conference on Energy Sustainability CY JUN 30-JUL 02, 2014 CL Seaport World Trade Ctr, Boston, MA SP ASME, Adv Energy Syst, ASME, Solar Energy Div HO Seaport World Trade Ctr AB Electrical power generation in austere settings, such as combat zones, places a heavy burden on the US Army; high costs in both dollars and lives lost require that every drop of fuel be used effectively and efficiently. In remote locations such as combat outposts (COPs) and small forward operating bases (FOBs) in Afghanistan, electrical power derived from the Army's standard Advanced Medium Mobile Power Sources (AMMPS) generator is even used to heat water for showers and heat living spaces. This heating requires conversion of thermal energy to mechanical energy, which is then converted to electrical energy and back to heat. Thus, a significant fuel savings could be realized through the more efficient production of heat. A combined heat and power system is proposed; efficiency is increased by routing the generator exhaust through simple ducting to a standard gas hot water heater to produce hot water with waste heat. With funding from the U.S. Army Rapid Equipping Force, cadets and faculty at the United States Military Academy designed, built and tested a system for under $1,000 in parts which was readily coupled to a 5 kW AMMPS generator to produce hot shower water. Results indicate a possible fuel savings of 1500-2000 gallons per year, 20-35% increased fuel utility, and the ability to provide 10-20 five gallon showers during every 5 hours of operation of each 5 kW generator. At a fuel cost of $20-50 per gallon in the deployed environment, and considering the large inventory of deployed generators, the payback for the Army could be tremendous. C1 [Tamm, Gunnar; Klosky, J. Ledlie; Baxter, Jacob; Grant, Luke; Melnick, Isaac; Young, Jacob] US Mil Acad, Dept Civil & Mech Engn, West Point, NY 10996 USA. RP Tamm, G (reprint author), US Mil Acad, Dept Civil & Mech Engn, West Point, NY 10996 USA. EM gunnar.tamm@usma.edu NR 7 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-4586-8 PY 2014 AR V001T01A008 PG 7 WC Energy & Fuels; Engineering, Mechanical SC Energy & Fuels; Engineering GA BD4XQ UT WOS:000361161900008 ER PT B AU Leemans, A Baker, M Tamm, G Andrews, D Johnson, E Hickey, B Martins, N AF Leemans, Adam Baker, Martin Tamm, Gunnar Andrews, Daniel Johnson, Elsa Hickey, Brendan Martins, Nathaniel GP ASME TI ENERGY SECURITY ANALYSIS FOR WEST POINT TRAINING CAMPS SO PROCEEDINGS OF THE ASME 8TH INTERNATIONAL CONFERENCE ON ENERGY SUSTAINABILITY, 2014, VOL 2 LA English DT Proceedings Paper CT ASME 8th International Conference on Energy Sustainability CY JUN 30-JUL 02, 2014 CL Seaport World Trade Ctr, Boston, MA SP ASME, Adv Energy Syst, ASME, Solar Energy Div HO Seaport World Trade Ctr AB The United States Military Academy has been charged with reaching Net Zero Energy consumption by 2020. Feasibility assessments to this point have neglected the field facilities used for military training, which are remote locations susceptible to power loss and subject to a higher rate structure for electricity than the rest of the installation. An energy security analysis methodology is described and applied to the training camps at West Point. This began with identifying the mission of the camps and critical power needs based on discussions with the customer, the Director of Cadet Military Training. Details of power and energy usage along with supply and delivery cost structure were provided by the utility and the facility Energy Manager. Conventional and renewable resource potentials were assessed to meet the load profile within financial constraints and funding opportunities unique to a federal government agency. The final recommendation is to incorporate three different technologies: a 50 kW photovoltaic solar system installed through a power purchase agreement, two small scale hydropower systems totaling 30 kW, and a lake based cooling system to provide air conditioning. The installation of these three systems would move the installation closer to the Net Zero Energy goal and lower the energy requirements to provide cooling. Altogether the proposed project would pay back in 16 years with an expected lifespan of 20-30 years. Batteries, generators, and pumped hydro were also examined as possible energy storage options and to shave the peak electrical load. However, the lack of on peak/off peak pricing made these options less viable. These recommendations will increase West Point's energy security, progress towards the Net Zero Energy goal, and provide cost savings over current utility expenditures. C1 [Leemans, Adam; Baker, Martin; Tamm, Gunnar; Andrews, Daniel; Johnson, Elsa; Hickey, Brendan; Martins, Nathaniel] US Mil Acad, Dept Civil & Mech Engn, West Point, NY 10996 USA. RP Leemans, A (reprint author), US Mil Acad, Dept Civil & Mech Engn, West Point, NY 10996 USA. EM gunnar.tamm@usnna.edu NR 7 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-4587-5 PY 2014 AR V002T11A009 PG 7 WC Construction & Building Technology; Energy & Fuels; Engineering, Mechanical SC Construction & Building Technology; Energy & Fuels; Engineering GA BD4XR UT WOS:000361162400062 ER PT B AU Wierzbicki, TA Lee, IC Gupta, AK AF Wierzbicki, Teresa A. Lee, Ivan C. Gupta, Ashwani K. GP ASME TI CATALYTIC AND NON-CATALYTIC COMBUSTION OF PROPANE IN A MESO-SCALE HEAT RECIRCULATING COMBUSTOR SO PROCEEDINGS OF THE ASME POWER CONFERENCE, 2014, VOL 1 LA English DT Proceedings Paper CT ASME Power Conference 2014 CY JUL 28-31, 2014 CL Baltimore, MD SP ASME, Power Div ID JET FUELS; PERFORMANCE; MICROCHANNELS; GENERATION; SYSTEM AB The results from the observed combustion behavior of propane over platinum and rhodium catalysts in a meso-scale heat recirculating combustor are presented. The extinction limits, conversion, product selectivity/yield, and activation energy using the two catalysts were compared in an effort to determine their performance using a liquid fuel. The extinction limits were also compared to those of non-catalytic combustion in the same reactor. The results showed that the addition of a catalyst greatly expanded the range of stable operating conditions, in respect to both extinction limits and flow rates supported. The Rh catalyst was found to exhibit a higher propane conversion rate, reaching a maximum of 90.4% at stoichiometric conditions (as opposed to the 61.4% offered by the Pt catalyst at lean conditions); however, the Pt catalyst had superior CO2 selectivity for most studied conditions, indicating higher combustion efficiency. The Pt catalyst also had a significantly smaller activation energy (13.8 kJ/mol) than the Rh catalyst (74.7 kJ/mol), except at equivalence ratios richer than Phi = 1.75 (corresponding to catalyst temperatures below 500 degrees C), where it abruptly changed to 211.4 kJ/mol, signifying a transition from diffusion-limited reactions to kinetically limited reactions at this point. The results reveal that Rh would be a more suitable catalyst for use in a liquid-fueled meso-scale combustor, as fuel conversion has been shown to be a limiting factor for combustion stability in these systems. C1 [Wierzbicki, Teresa A.; Lee, Ivan C.] US Army Res Lab, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA. [Gupta, Ashwani K.] Univ Maryland, Dept Mech Engn, College Pk, MD 20742 USA. RP Wierzbicki, TA (reprint author), US Army Res Lab, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA. NR 24 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-4608-7 PY 2014 AR V001T01A013 PG 7 WC Energy & Fuels; Engineering, Mechanical SC Energy & Fuels; Engineering GA BD4XP UT WOS:000361161600013 ER PT S AU Enos, JR AF Enos, James R. BE Madni, AM Boehm, B TI Modifying the X-Matrix to Capture the Joint Capability Architecture SO 2014 CONFERENCE ON SYSTEMS ENGINEERING RESEARCH SE Procedia Computer Science LA English DT Proceedings Paper CT Conference on Systems Engineering Research CY MAR 20-22, 2014 CL Redondo Beach, CA DE Enterprise Architecture; X-Matrix; Joint Capability Areas AB The Department of Defense (DoD) manages programs of systems from concept through development to production with Joint Capability Areas (JCAs). JCAs are a standardized grouping of capabilities that enable DoD decision makers to allocate resources based on a programs contribution to joint operations. Additionally, the DoD has established Universal Joint Tasks (UJTs) to serve as a common language for describing functions a system performs across the four services. Similar to JCAs, a system performs one or more UJTs in support of the joint war fight. Although JCAs and UJTs are well described and understood by the joint community within the DoD, the DoD lacks a method for visualizing the links between program, JCAs, and UJTs at the enterprise level. Enterprise Architecting is an approach for analyzing an enterprise level system and developing candidate architectures for the enterprise to deliver value. Enterprise Architecture tools, specifically, the X-Matrix provides an opportunity for the DoD to visualize these links to ensure alignment of programs to JCAs and UJTs. Additionally, the X-Matrix enables DoD decision makers to understand potential gaps or unnecessary redundancies at the enterprise level. Given the current fiscal reality in the DoD, analysts must provide leaders with data based recommendations on systems to ensure that the DoD is being efficient with their limited resources. This modification of the X-Matrix enables the visualization of essential links between programs, the form of the enterprise, and the JCAs and UJTs, the function of the enterprise. It provides DoD leadership with a tool to visualize the impacts of resourcing decisions and potentially make better investments in programs to support the joint warfighter. (C) 2014 The Authors. Published by Elsevier B.V. C1 US Mil Acad, West Point, NY 10996 USA. RP Enos, JR (reprint author), US Mil Acad, Mahan Hall, West Point, NY 10996 USA. NR 14 TC 0 Z9 0 U1 0 U2 0 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 1877-0509 J9 PROCEDIA COMPUT SCI PY 2014 VL 28 BP 87 EP 94 DI 10.1016/j.procs.2014.03.012 PG 8 WC Computer Science, Information Systems; Computer Science, Software Engineering; Computer Science, Theory & Methods SC Computer Science GA BD4JF UT WOS:000360837700011 ER PT S AU Dabkowski, M Valerdi, R Farr, J AF Dabkowski, Matthew Valerdi, Ricardo Farr, John BE Madni, AM Boehm, B TI Exploiting Architectural Communities in Early Life Cycle Cost Estimation SO 2014 CONFERENCE ON SYSTEMS ENGINEERING RESEARCH SE Procedia Computer Science LA English DT Proceedings Paper CT Conference on Systems Engineering Research CY MAR 20-22, 2014 CL Redondo Beach, CA DE Model Based Systems Engineering; DoD Architecture Framework; COSYSMO; network science; community detection AB System architectures evolve over time. Accordingly, the dynamic properties of architectures reflect how systems respond to change, and this response ultimately impacts cost. In prior work we make an explicit connection between the architectural diagrams of Model-Based Systems Engineering (MBSE), parametric cost estimation, and network science. Specifically, by treating the DoD Architecture Framework (DoDAF) Systems View 3 (SV3) as an adjacency matrix, we assess how the addition of a new subsystem to an immature architecture might grow the existing network. With the subsequent application of parametric cost modeling, we translate anticipated growth into expected cost, thereby quantifying the impact of change. This paper refines that approach. In particular, by using the Girvan-Newman algorithm, the SV3 is initially divided into groups of subsystems such that the number of interfaces is dense within and sparse between groups. Based on this division into "architectural communities" and the prevalence of bridging ties, interfaces generated by the addition of a new subsystem can be faithfully integrated into the existing architecture, adding validity to our growth mechanism. This procedure is illustrated in detail with an example that highlights the importance of this refinement, and it is incorporated within a Monte Carlo simulation that allows the distribution of future costs to be estimated and assessed. (C) 2014 The Authors. Published by Elsevier B.V. C1 [Dabkowski, Matthew; Valerdi, Ricardo] Univ Arizona, Tucson, AZ 85721 USA. [Farr, John] US Mil Acad, West Point, NY 10996 USA. RP Dabkowski, M (reprint author), Univ Arizona, 1127 E James E Rogers Way, Tucson, AZ 85721 USA. EM mfd1@email.arizona.edu NR 21 TC 0 Z9 1 U1 0 U2 0 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 1877-0509 J9 PROCEDIA COMPUT SCI PY 2014 VL 28 BP 95 EP 102 DI 10.1016/j.procs.2014.03.013 PG 8 WC Computer Science, Information Systems; Computer Science, Software Engineering; Computer Science, Theory & Methods SC Computer Science GA BD4JF UT WOS:000360837700012 ER PT S AU Young, SH Mazzuchi, TA Sarkani, S AF Young, Stuart H. Mazzuchi, Thomas A. Sarkani, Shahram BE Madni, AM Boehm, B TI A Model-based Framework for Predicting Performance in Self-adaptive Systems SO 2014 CONFERENCE ON SYSTEMS ENGINEERING RESEARCH SE Procedia Computer Science LA English DT Proceedings Paper CT Conference on Systems Engineering Research CY MAR 20-22, 2014 CL Redondo Beach, CA DE Autonomous robots; Complex systems; Self-adaptive systems; Autonomy ID NAVIGATION; PROGRAM; TERRAIN; ROBOTS AB In recent years, the Department of Defense (DoD) has sought to develop military systems with increasing levels of autonomy. There has been an increase in requirements and desired capabilities that call for the semi-autonomous or autonomous performance of tasks. Military robot systems are an example of such complex systems. As the DoD develops these complex systems it is evident, based on recent research, that in order to achieve the desired capabilities the systems must adapt and learn to improve their performance and become more autonomous. However, it is cost prohibitive and impractical to evaluate self-adaptive systems in all possible scenarios and environments. As a result, it is desirable to improve our ability to understand how autonomous systems will perform in order to influence military acquisition decisions. Prior work has sought to characterize the environment or the performance of unmanned systems based on levels of autonomy and suggested that environmental complexity is a strong predictor of performance of mobile robot systems. However performance measures of unmanned systems dealing with complex and changing environments have been difficult to measure quantitatively because it is difficult to delineate the general operational domains of the unmanned systems or how to determine if an unmanned system satisfies capability specifications or expectations. This paper describes the development of a model-based framework for predicting the performance of self-adaptive systems, specifically a navigation task for mobile military robot systems. By developing a quantitative model of performance based on the complexity of the environment, including slope and vegetation, we can estimate the performance of a system in new regions based on performance in known regions. Using simulation and data from prior experiments, we demonstrate the ability to predict the performance in environments that have not been tested. In order to validate our model, we compare the model results to data from previous DARPA-led research experiments. (C) 2014 The Authors. Published by Elsevier B.V. C1 [Young, Stuart H.] Army Res Lab, Adelphi, MD 20783 USA. [Mazzuchi, Thomas A.; Sarkani, Shahram] George Washington Univ, Washington, DC 20052 USA. RP Young, SH (reprint author), Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM syoung1@gwu.edu NR 26 TC 0 Z9 0 U1 1 U2 3 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 1877-0509 J9 PROCEDIA COMPUT SCI PY 2014 VL 28 BP 513 EP 521 DI 10.1016/j.procs.2014.03.063 PG 9 WC Computer Science, Information Systems; Computer Science, Software Engineering; Computer Science, Theory & Methods SC Computer Science GA BD4JF UT WOS:000360837700061 ER PT S AU Arruda, J Gavrilovski, A Ahn, B Chae, HG Spero, E Mavris, DN AF Arruda, James Gavrilovski, Alek Ahn, Bruce Chae, Han-Gil Spero, Eric Mavris, Dimitri N. BE Madni, AM Boehm, B TI The capability assessment and tradeoff environment (CATE) for advanced aerospace vehicle and technology assessment SO 2014 CONFERENCE ON SYSTEMS ENGINEERING RESEARCH SE Procedia Computer Science LA English DT Proceedings Paper CT Conference on Systems Engineering Research CY MAR 20-22, 2014 CL Redondo Beach, CA DE Rotorcraft; Technology Assessment; Technology Portfolios; JMR; Technology Demonstrator; Decision Support Environment; Future Vertical Lift AB New, advanced aerospace vehicles are being considered for inclusion in the existing fleet of Joint Service air vehicles, based on the evolving needs of these organizations. The difficulty for design teams and the requirements community is arriving at a good estimate of what a particular configuration may look like, as well as what technologies are needed to enable it, given a set of strict requirements. The Capability Assessment and Tradeoff Environment (CATE) has been created to support aerospace vehicle decision making with structured vehicle and technology assessment processes and tools. The CATE enables rapid evaluation and visualization of vehicles and trades, off-design performance assessment, capability gap detection, technology definitions, and technology portfolio selection. In this paper, the creation of the CATE is outlined, and the processes it enables for vehicle and technology assessment are described. (C) 2014 The Authors. Published by Elsevier B.V. C1 [Arruda, James; Gavrilovski, Alek; Ahn, Bruce; Chae, Han-Gil; Mavris, Dimitri N.] Georgia Inst Technol, Atlanta, GA 30332 USA. [Spero, Eric] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Spero, E (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. EM eric.spero.civ@mail.mil NR 9 TC 0 Z9 0 U1 0 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 1877-0509 J9 PROCEDIA COMPUT SCI PY 2014 VL 28 BP 583 EP 590 DI 10.1016/j.procs.2014.03.071 PG 8 WC Computer Science, Information Systems; Computer Science, Software Engineering; Computer Science, Theory & Methods SC Computer Science GA BD4JF UT WOS:000360837700069 ER PT S AU Spero, E Avera, MP Valdez, PE Goerger, SR AF Spero, Eric Avera, Michael P. Valdez, Pierre E. Goerger, Simon R. BE Madni, AM Boehm, B TI Tradespace Exploration for the Engineering of Resilient Systems SO 2014 CONFERENCE ON SYSTEMS ENGINEERING RESEARCH SE Procedia Computer Science LA English DT Proceedings Paper CT Conference on Systems Engineering Research CY MAR 20-22, 2014 CL Redondo Beach, CA DE Tradespace exploration; decision analysis; ERS AB Tradespace exploration supports the Systems Engineering Technical Management Process of Decision Analysis by identifying compromises, revealing opportunities, and communicating the impacts of decisions across a system's development lifecycle. Critical program decisions are made based on the outcomes of trades; trades being performed with multiple types and quantities of data coming out of tools and methods employing qualitative and quantitative analyses. Tradespace exploration for Engineered Resilient Systems (ERS) is envisioned to coalesce pertinent information tuned to specific decision makers, at the appropriate time, presenting a holistic view of decision impacts on required system capabilities. This study provides an ERS view of tradespace exploration, which reveals that having a valid set of attributes, and an understanding of how a cross-section of tools can satisfy them, is insufficient - what is needed is a deeper understanding of how these tools are used and, more importantly, how they can be used when performing tradespace exploration in support of the Decision Analysis Process. Gaining this understanding will enable users to better assess if they possess the appropriate tradespace exploration tools. A holistic view of 81 candidate tradespace exploration tools is provided. This study seeks to address a fundamental aspect of tradespace exploration by assembling a "best common practice" process for their requirements, identifying a set of attributes that defines an ideal tradespace exploration tool, and surveying existing tools that satisfy these attributes. In this way, a set of tools can be selected to enable the ERS tradespace vision on a particular project. A paradigm shift towards common tradespace methods, tools, cost models, and steps is emphasized. (C) 2014 The Authors. Published by Elsevier B.V. C1 [Spero, Eric] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. [Avera, Michael P.] Amer Soc Engn Educ, Washington, DC 20036 USA. [Valdez, Pierre E.] Georgia Inst Technol, Atlanta, GA 30332 USA. [Goerger, Simon R.] US Army Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. RP Spero, E (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. EM eric.spero.civ@mail.mil NR 25 TC 2 Z9 2 U1 1 U2 2 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 1877-0509 J9 PROCEDIA COMPUT SCI PY 2014 VL 28 BP 591 EP 600 DI 10.1016/j.procs.2014.03.072 PG 10 WC Computer Science, Information Systems; Computer Science, Software Engineering; Computer Science, Theory & Methods SC Computer Science GA BD4JF UT WOS:000360837700070 ER PT S AU Spero, E Bloebaum, CL German, BJ Pyster, A Ross, AM AF Spero, Eric Bloebaum, Christina L. German, Brian J. Pyster, Art Ross, Adam M. BE Madni, AM Boehm, B TI A Research Agenda for Tradespace Exploration and Analysis of Engineered Resilient Systems SO 2014 CONFERENCE ON SYSTEMS ENGINEERING RESEARCH SE Procedia Computer Science LA English DT Proceedings Paper CT Conference on Systems Engineering Research CY MAR 20-22, 2014 CL Redondo Beach, CA DE tradespace; search; exploration; multi-disciplinary optimization; visualization; value; decisions AB This paper describes the activity of a workshop on Data-Driven Tradespace Exploration and Analysis: A Key Technical Thrust of Engineered Resilient Systems (ERS). The workshop was attended by 40 academic, government, and industry researchers and practitioners involved in tradespace exploration for a variety of engineering domains. The one-and-one-half day workshop sought to develop near and far term tradespace technology research recommendations for the ERS Priority Steering Council (PSC) Lead. To determine promising research areas, workshop attendees were asked to describe desired tradespace capabilities, the associated current approach and its deficiencies, and gaps between the two states. These research areas were summarized in statements of need, supporting rationale, and investment timeframe. Resilience in the context of ERS is more than robustness; resilience implies that when the system is placed into an environment in which it was not originally intended to operate, after some degradation in performance, the system can be adapted or reconfigured to perform at its intended levels. To support design for resilience, more alternatives must be generated earlier, considered longer, explored over multiple, dynamic alternative futures, and searched exhaustively. The workshop described in this paper was organized to discuss current methods, process, and tools for performing these tradespace analysis related tasks and to better understand existing tradespace capabilities and their suitability for ERS. (C) 2014 The Authors. Published by Elsevier B.V. C1 [Spero, Eric] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. [Bloebaum, Christina L.] Iowa State Univ, Ames, IA 50011 USA. [German, Brian J.] Georgia Inst Technol, Atlanta, GA 30332 USA. [Pyster, Art] Stevens Inst Technol, Washington, DC 20004 USA. [Ross, Adam M.] MIT, Cambridge, MA 02139 USA. RP Spero, E (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. EM eric.spero.civ@mail.mil NR 6 TC 2 Z9 2 U1 1 U2 2 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 1877-0509 J9 PROCEDIA COMPUT SCI PY 2014 VL 28 BP 763 EP 772 DI 10.1016/j.procs.2014.03.091 PG 10 WC Computer Science, Information Systems; Computer Science, Software Engineering; Computer Science, Theory & Methods SC Computer Science GA BD4JF UT WOS:000360837700089 ER PT S AU Goerger, SR Madni, AM Eslinger, OJ AF Goerger, Simon R. Madni, Azad M. Eslinger, Owen J. BE Madni, AM Boehm, B TI Engineered Resilient Systems: A DoD Perspective SO 2014 CONFERENCE ON SYSTEMS ENGINEERING RESEARCH SE Procedia Computer Science LA English DT Proceedings Paper CT Conference on Systems Engineering Research CY MAR 20-22, 2014 CL Redondo Beach, CA DE rResilience; decision analysis; ERS; Engineered Resilient Systems; resilience engineering AB Department of Defense (DoD) systems are required to be trusted and effective in a wide range of operational contexts with the ability to respond to new or changing conditions through modified tactics, appropriate reconfiguration, or replacement. As importantly, these systems are required to exhibit predictable and graceful degradation outside their designed performance envelope. For these systems to be included in the force structure, they need to be manufacturable, readily deployable, sustainable, easily modifiable, and cost-effective. Collectively, these requirements inform the definition of resilient DoD systems. This paper explores the properties and tradeoffs for engineered resilient systems in the military context. It reviews various perspectives on resilience, overlays DoD requirements on these perspectives, and presents DoD challenges in realizing and rapidly fielding resilient systems. This paper also presents promising research themes that need to be pursued by the research community to help the DoD realize the vision of affordable, adaptable, and effective systems. This paper concludes with a discussion of specific DoD systems that can potentially benefit from resilience and stresses the need for sustaining a community of interest in this important area. (C) 2014 The Authors. Published by Elsevier B.V. C1 [Goerger, Simon R.; Eslinger, Owen J.] US Army Engineer Res & Dev Ctr ERDC, Vicksburg, MS 39180 USA. [Madni, Azad M.] Univ So Calif, Los Angeles, CA 90089 USA. RP Goerger, SR (reprint author), US Army Engineer Res & Dev Ctr ERDC, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM Simon.R.Goerger@usace.army.mil NR 15 TC 2 Z9 2 U1 1 U2 3 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 1877-0509 J9 PROCEDIA COMPUT SCI PY 2014 VL 28 BP 865 EP 872 DI 10.1016/j.procs.2014.03.103 PG 8 WC Computer Science, Information Systems; Computer Science, Software Engineering; Computer Science, Theory & Methods SC Computer Science GA BD4JF UT WOS:000360837700100 ER PT S AU Mell, P Harang, RE AF Mell, Peter Harang, Richard E. GP IEEE TI Using Network Tainting to Bound the Scope of Network Ingress Attacks SO 2014 EIGHTH INTERNATIONAL CONFERENCE ON SOFTWARE SECURITY AND RELIABILITY SE International Conference on Software Security and Reliability LA English DT Proceedings Paper CT 8th International Conference on Software Security and Reliability (SERE) CY JUN 30-JUL 02, 2014 CL San Francisco, CA SP IEEE Comp Soc, IEEE Reliabil Soc DE network tainting; complex networks; scale-free; security AB This research describes a novel security metric, network taint, which is related to software taint analysis. We use it here to bound the possible malicious influence of a known compromised node through monitoring and evaluating network flows. The result is a dynamically changing defense-in-depth map that shows threat level indicators gleaned from monotonically decreasing threat chains. We augment this analysis with concepts from the complex networks research area in forming dynamically changing security perimeters and measuring the cardinality of the set of threatened nodes within them. In providing this, we hope to advance network incident response activities by providing a rapid automated initial triage service that can guide and prioritize investigative activities. C1 [Mell, Peter] NIST, Gaithersburg, MD 20899 USA. [Harang, Richard E.] US Army Res Lab, Adelphi, MD USA. [Harang, Richard E.] ICF Int, Baltimore, MD USA. RP Mell, P (reprint author), NIST, Gaithersburg, MD 20899 USA. EM peter.mell@nist.gov; richard.e.harang.ctr@mail.mil NR 9 TC 1 Z9 1 U1 1 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2378-3877 BN 978-1-4799-4296-1 J9 INT CONF SOFTW SECUR PY 2014 BP 206 EP 215 DI 10.1109/SERE.2014.34 PG 10 WC Computer Science, Software Engineering; Computer Science, Theory & Methods SC Computer Science GA BD4IR UT WOS:000360819100022 ER PT J AU Hanratty, T Dumer, J Hammell, R Miao, S Tang, Z AF Hanratty, Timothy Dumer, John Hammell, Robert, II Miao, Sheng Tang, Ziying BE Gibbs, M TI Tuning Fuzzy Membership Functions to Improve Value of Information Calculations SO 2014 IEEE CONFERENCE ON NORBERT WIENER IN THE 21ST CENTURY (21CW) LA English DT Proceedings Paper CT IEEE Conference on Norbert Wiener in the 21st Century (21CW) - Driving Technology's Future CY JUN 24-26, 2014 CL Boston, MA SP IEEE DE Value of Information; Fuzzy Associative Memory; NATO Standard Agreement 2022 (Information Valuation) AB A major tenet of the US Army's data-to-decision initiative and a primary challenge for military commanders and their staff is the ability to shorten the cycle time from data gathering to making decisions. Paramount to this process is the ability to better assess the applicability and relevance of information for decisions in complex military environments. Towards this end, the Army Research Laboratory, in collaboration with Towson University, has embarked on a research initiative to experimentally characterize how analysts perceive the value of information (VoI) and subsequently model and test solutions. This paper presents the process used to extend the current fuzzy VoI system to allow user-defined membership functions that consider various domain decompositions using both triangular and trapezoidal fuzzy sets, and the assessment of their efficacy to current military operations. C1 [Hanratty, Timothy; Dumer, John] US Army Res Lab, Computat Informat Sci Directorate, Aberdeen Proving Ground, MD 21005 USA. [Hammell, Robert, II; Miao, Sheng; Tang, Ziying] Towson Univ, Dept Comp & Informat Sci, Towson, MD USA. RP Hanratty, T (reprint author), US Army Res Lab, Computat Informat Sci Directorate, Aberdeen Proving Ground, MD 21005 USA. EM timothy.hanratty@us.army.mil; rhammell@towson.edu NR 12 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-4562-7 PY 2014 PG 7 WC Computer Science, Artificial Intelligence; Computer Science, Interdisciplinary Applications; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BD4JB UT WOS:000360828700006 ER PT S AU Petersen, EA Tillinghast, RC Dabiri, S Gonzalez, MC AF Petersen, Edward A. Tillinghast, Ralph C. Dabiri, Shahram Gonzalez, Maria C. GP IEEE TI Combining World Class Research and Development Philosophy with Elementary and Secondary School Teaching Practices SO 2014 IEEE INTEGRATED STEM EDUCATION CONFERENCE (ISEC) SE Integrated STEM Education Conference LA English DT Proceedings Paper CT IEEE Integrated STEM Education Conference (ISEC) CY MAR 08, 2014 CL Princeton, NJ SP IEEE, IEEE Reg 1, IEEE Educ Soc, IEEE Princeton Cent Jersey Sect DE STEM; Education; Engineering Mentors; DOTC STEM; Picatinny Arsenal AB The need for Science, Technology, Engineering, and Mathematics (STEM) education programs in elementary and secondary schools is a goal most professional educators and scientists support. What form these programs take can lead to considerable debate. In the search for some common ground the authors of this paper envisioned a school where children want to attend, where professional scientists and engineers work together with creative dedicated experienced teachers, and where the curriculum contains activities relevant to today's technologies and nurtures the creativity necessary to develop the technologies of the future. This school would be in a location where the students would have access to actual working laboratories in which engineers use state of the art equipment to solve real problems. The school environment would foster the creation of Integrated Product Teams (IPT) where girls are as excited and deeply involved as boys and students gain experience making presentations of their work to research and development professionals with comfort and confidence. Students develop the understanding that there is no shame in being wrong as long as they utilize what was learned to redesign and try again. Students willingly share knowledge with other students, desire to continue working instead of taking snack and lunch breaks, and at the end of the day when parents arrive to take their children home, these students beg for permission to stay and continue their assignments. If the above vision seems like pure fantasy, one need only visit the Picatinny STEM Academy Summer Enrichment Program. C1 [Petersen, Edward A.; Dabiri, Shahram; Gonzalez, Maria C.] US Army, DOTC STEM Off, ARDEC, Picatinny Arsenal, NJ 07885 USA. [Tillinghast, Ralph C.] US Army, Collaborat Innovat Lab, ARDEC, Picatinny Arsenal, NJ USA. RP Petersen, EA (reprint author), US Army, DOTC STEM Off, ARDEC, Picatinny Arsenal, NJ 07885 USA. EM edward.a.petersen.ctr@mail.mil; ralph.c.tillinghast.civ@mail.mil; shahram.dabiri1.civ@mail.mil; maria.c.gonzalez1.ctr@mail.mil NR 9 TC 0 Z9 0 U1 1 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2330-331X BN 978-1-4799-3229-0 J9 INTEGR STEM EDU CONF PY 2014 PG 7 WC Education, Scientific Disciplines; Engineering, Multidisciplinary SC Education & Educational Research; Engineering GA BD4IX UT WOS:000360821700036 ER PT S AU Tillinghast, RC Wright, MT Arnold, RD Zunino, JL Pannullo, TL Dabiri, S Petersen, EA Gonzalez, MC AF Tillinghast, Ralph C. Wright, Michael T. Arnold, Ross D. Zunino, James L. Pannullo, Traci L. Dabiri, Shahram Petersen, Edward A. Gonzalez, Maria C. GP IEEE TI Integrating Three Dimensional Visualization and Additive Manufacturing into K-12 Classrooms SO 2014 IEEE INTEGRATED STEM EDUCATION CONFERENCE (ISEC) SE Integrated STEM Education Conference LA English DT Proceedings Paper CT IEEE Integrated STEM Education Conference (ISEC) CY MAR 08, 2014 CL Princeton, NJ SP IEEE, IEEE Reg 1, IEEE Educ Soc, IEEE Princeton Cent Jersey Sect DE 3D Printing; 3D Scanning; 3D Visualization; Additive Manufacturing; Education; STEM; Picatinny Arsenal AB With the increased availability and affordability of three dimensional visualization and additive manufacturing tools, the opportunity to bring these technologies into the classroom has never been greater. Utilizing 3D scanners, 3D modeling software and 3D printers in the classroom opens the door for hands-on STEM and STEaM education. This paper outlines methods and approaches to introduce these technologies into K-12 classrooms. Including technologies available to educators, methods and approaches to bring these technologies into the classroom and results and lessons learned from in-school pilot programs related to these technologies. Overall this paper is intended to aid educators in bringing these technologies into the classroom to broaden STEM and STEaM education. C1 [Tillinghast, Ralph C.] US Army, Collaborat Innovat Lab, ARDEC, Picatinny Arsenal, NJ 07885 USA. [Wright, Michael T.; Arnold, Ross D.; Zunino, James L.] US Army, ARDEC, Picatinny Arsenal, NJ USA. [Pannullo, Traci L.] Ridge & Valley Charter Sch, Blairstown, NJ USA. [Dabiri, Shahram; Petersen, Edward A.; Gonzalez, Maria C.] US Army, DOTC STEM Off, ARDEC, Picatinny Arsenal, NJ USA. RP Tillinghast, RC (reprint author), US Army, Collaborat Innovat Lab, ARDEC, Picatinny Arsenal, NJ 07885 USA. EM ralph.c.tillinghast.civ@mail.mil; michael.t.wright88.civ@mail.mil; ross.d.arnold4.civ@mail.mil; james.l.zunino.civ@mail.mil; traci.pannullo@ridgeandvalley.org; shahram.dabiri1.civ@mail.mil; edward.a.petersen.ctr@mail.mil; maria.c.gonzalez1.ctr@mail.mil NR 14 TC 0 Z9 0 U1 1 U2 5 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2330-331X BN 978-1-4799-3229-0 J9 INTEGR STEM EDU CONF PY 2014 PG 7 WC Education, Scientific Disciplines; Engineering, Multidisciplinary SC Education & Educational Research; Engineering GA BD4IX UT WOS:000360821700046 ER PT S AU Lee, JH Shubin, I Yao, J Bickford, J Luo, Y Lin, SY Djordjevic, SS Thacker, HD Cunningham, JE Raj, K Zheng, XZ Krishnamoorthy, AV AF Lee, Jin Hyoung Shubin, Ivan Yao, Jin Bickford, Justin Luo, Ying Lin, Shiyun Djordjevic, Stevan S. Thacker, Hiren D. Cunningham, John E. Raj, Kannan Zheng, Xuezhe Krishnamoorthy, Ashok V. GP IEEE TI High power and energy-efficient WDM Si/III-V hybrid externalcavity lasers SO 2014 IEEE OPTICAL INTERCONNECTS CONFERENCE SE Optical Interconnects Conference LA English DT Proceedings Paper CT 3rd IEEE-Photonics-Society Optical Interconnects Conference CY MAY 04-07, 2014 CL San Diego, CA SP IEEE Photon Soc, Huawei, Intel, HP Labs, Oracle Labs ID WAVELENGTH TUNABLE LASER; SILICON AB An efficient Si hybrid external cavity laser with a micro-ring reflector is fabricated on SOI platform. The laser output power reaches 20 mW and the highest wall-plug efficiency of 7.8% is measured in an un-cooled condition. C1 [Lee, Jin Hyoung; Shubin, Ivan; Yao, Jin; Luo, Ying; Lin, Shiyun; Djordjevic, Stevan S.; Thacker, Hiren D.; Cunningham, John E.; Raj, Kannan; Zheng, Xuezhe; Krishnamoorthy, Ashok V.] Oracle, San Diego, CA 92121 USA. [Bickford, Justin] Army Res Lab, Adelphi, MD 20783 USA. RP Lee, JH (reprint author), Oracle, 9515 Towne Ctr Dr, San Diego, CA 92121 USA. NR 7 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2376-8665 BN 978-1-4799-2468-4 J9 OPT INTERCONNECT C PY 2014 BP 75 EP 76 PG 2 WC Engineering, Electrical & Electronic; Optics SC Engineering; Optics GA BD4QY UT WOS:000361019400034 ER PT J AU Kung, P Mohanta, A Simmons, JG Everitt, HO Shen, G Waters, J Kim, SM AF Kung, Patrick Mohanta, Antaryami Simmons, Jay G., Jr. Everitt, Henry O. Shen, Gang Waters, Joseph Kim, Seongsin M. GP IEEE TI Synthesis and Optical Properties of Undoped and Aluminum doped ZnO Nanowires for Optoelectronic Nanodevice Applications SO 2014 IEEE PHOTONICS SOCIETY SUMMER TOPICAL MEETING SERIES LA English DT Proceedings Paper CT IEEE-Photonics-Society Summer Topical Meeting Series CY JUL 14-16, 2014 CL Montreal, CANADA SP IEEE Photon Soc, IEEE Comp Soc, IEEE ID GROWTH C1 [Kung, Patrick; Mohanta, Antaryami; Shen, Gang; Waters, Joseph; Kim, Seongsin M.] Univ Alabama, Dept Elect & Comp Engn, Tuscaloosa, AL 35487 USA. [Everitt, Henry O.] US Army Aviat & Missile Res, Dev & Engn Ctr AMRDEC, Redstone Arsenal, AL 35898 USA. RP Kung, P (reprint author), Univ Alabama, Dept Elect & Comp Engn, Tuscaloosa, AL 35487 USA. OI Everitt, Henry/0000-0002-8141-3768 NR 5 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-2767-8 PY 2014 BP 198 EP 199 DI 10.1109/SUM.2014.108 PG 2 WC Engineering, Electrical & Electronic; Optics SC Engineering; Optics GA BD4QL UT WOS:000361018200101 ER PT J AU Grant, SA Arcone, SA Boitnott, GE AF Grant, S. A. Arcone, S. A. Boitnott, G. E. BE Lambot, S Giannopoulos, A Pajewski, L Andre, F Slob, E Craeye, C TI Maxwell-Wagner-Sillars, Adsorbed Water, and Free-Water Dielectric Relaxations within a Hydrated Arid-Zone Calcic Soil SO PROCEEDINGS OF THE 2014 15TH INTERNATIONAL CONFERENCE ON GROUND PENETRATING RADAR (GPR 2014) LA English DT Proceedings Paper CT 15th International Conference on Ground Penetrating Radar (GPR) CY JUN 30-JUL 04, 2014 CL Brussels, BELGIUM SP European Cooperat Sci & Technol Act TU 1208 Civil Engn Applicat Ground Penetrating Radar, Univ Catholique Louvain, Geoscanners, IDS, GSSI, Radar Syst, Geotech, Roadscanners, 3D Radar, Allied Associates, Geomatrix Earth Sci Ltd, Utsi Elect, Transient Technologies, Mala, Sensors & Softwares, Radarteam Sweden, Rohde & Schwarz, European GPR Assoc, IEEE Geoscience & Remote Sensing Soc DE Adsorbed water; dielectric permittivity; free water; Maxwell-Wagner-Sillars polarization; dielectric relaxation; soil AB We measured the broadband (40 Hz-20 GHz) relative dielectric permittivity of sieved surficial samples of an arid-zone soil. The soil samples were equilibrated at 25 degrees C with relative humidities of 43, 54, 84, and 97 %. Debye-like Maxwell-Wagner-Sillars (MWS) polarization relaxation times of 309, 227, and 73 ns were calculated for the soil samples equilibrated at relative humidities of 43, 54, and 84 %, respectively. Due to electrode polarization, MWS polarization relaxations could be not be discerned on the soil sample equilibrated at 97 % relative humidity. The measured differences between the static and high-frequency relative permittivity (epsilon(s) - epsilon(infinity)) due to MWS polarization were between 25 and 45 times that of the oven dry soil. This would cause the MWS relaxation to increase radar-wave attenuation rates at frequencies as high as 1 GHz. We found Debye-type relaxation times associated with adsorbed water of 13, 15, 17, 19, and 22 ps for an oven-dry sample and ones equilibrated at at relative humidities of 43, 54, 84, and 97 %, respectively. These frequencies are higher than previously thought. This progression with water contents may be due to the increase in soil solution salinity with increasing water contents. They were not likely caused by free water since a weakly resolved relaxation could be discerned corresponding to a relaxation time of approximately 8 ps, as expected for free-water. C1 [Grant, S. A.; Arcone, S. A.; Boitnott, G. E.] US Anny Engn Res & Dev Ctr, Hanover, NH 03755 USA. RP Grant, SA (reprint author), US Anny Engn Res & Dev Ctr, 72 Lyme Rd, Hanover, NH 03755 USA. EM steven.a.grant@erdc.dren.mil; steven.a.arcone@erdc.dren.mil; ginger.e.boitnott@erdc.dren.mil NR 12 TC 1 Z9 1 U1 1 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-6789-6 PY 2014 BP 161 EP 165 PG 5 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BD4QC UT WOS:000361002500032 ER PT J AU Arcone, S Grant, S Boitnott, G AF Arcone, Steven Grant, Steven Boitnott, Ginger BE Lambot, S Giannopoulos, A Pajewski, L Andre, F Slob, E Craeye, C TI Broadband TDR Permittivity Spectra of Lossy Soils at Medium to High Water Contents: Separation of Electrode Polarization from Maxwell-Wagner Relaxation by Modeling SO PROCEEDINGS OF THE 2014 15TH INTERNATIONAL CONFERENCE ON GROUND PENETRATING RADAR (GPR 2014) LA English DT Proceedings Paper CT 15th International Conference on Ground Penetrating Radar (GPR) CY JUN 30-JUL 04, 2014 CL Brussels, BELGIUM SP European Cooperat Sci & Technol Act TU 1208 Civil Engn Applicat Ground Penetrating Radar, Univ Catholique Louvain, Geoscanners, IDS, GSSI, Radar Syst, Geotech, Roadscanners, 3D Radar, Allied Associates, Geomatrix Earth Sci Ltd, Utsi Elect, Transient Technologies, Mala, Sensors & Softwares, Radarteam Sweden, Rohde & Schwarz, European GPR Assoc, IEEE Geoscience & Remote Sensing Soc DE dielectric permittivity; electrode polarization; Maxwell-Wagner; soils ID DIELECTRIC-SPECTROSCOPY; COMPLEX PERMITTIVITY; DOMAIN AB We discuss complex permittivity spectra of two lossy soils measured from 6 kHz to 6 GHz using time domain reflectometry, in which Maxwell-Wagner relaxation (MWR) is present but also unwanted electrode polarization EP, mainly below 1 MHz, is strong. The soils are mostly quartz, with one having lesser calcite and the other lesser gypsum. Volumetric water contents ranged from 8.5-30.9%. We use a simple model that adds an EP diffusion term to Debye-type terms for the MWR and free water relaxation centered near 19 GHz, and which allows us to separate the EP from the MWR. All samples show MWRs centered from 1-196 MHz, regardless of water content, and with small to significant Cole-Cole factors. The increasing water content diminishes the effect of MWR, likely by decreasing the conductive and dielectric contrasts between isolated inclusions and the soil matrix, but still can strongly contribute to attenuation rate across the 100-1000 MHz GPR bandwidth. C1 [Arcone, Steven; Grant, Steven; Boitnott, Ginger] US Army ERDC CRREL, Hanover, NH 03755 USA. RP Arcone, S (reprint author), US Army ERDC CRREL, Hanover, NH 03755 USA. EM Steven.A.Arcone@erdc.dren.mil NR 19 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-6789-6 PY 2014 BP 186 EP 191 PG 6 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BD4QC UT WOS:000361002500037 ER PT B AU Yoo, J AF Yoo, JinHyoeng GP ASME TI A MODELING OF FE-GA MAGNETOSTRICTIVE SHUNT DAMPER SO PROCEEDINGS OF THE ASME CONFERENCE ON SMART MATERIALS, ADAPTIVE STRUCTURES AND INTELLIGENT SYSTEMS, 2014, VOL 1 LA English DT Proceedings Paper CT 7th Annual ASME Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS) CY SEP 08-10, 2014 CL Newport, RI SP ASME, Aerospace Div ID GALFENOL AB This study presents mechanical energy dissipation with a proof-of-concept prototype magnetostrictive (Fe-Ga alloy, galfenol) based shunt circuit using passive electrical components. Magnetostrictive material can harvest electricity out of the structural vibrations based on the Villari effect using permanent magnet and pickup coil configuration. The device in this study consists of a polycrystalline galfenol strip bonded to a brass cantilever beam. Two brass pieces, each containing a permanent magnet, are used to mass load at the end of the beam and to provide a magnetic bias field through the galfenol strip. The voltage induced in an induction coil closely wound around the cantilever beam captures the time rate of change of magnetic flux within the galfenol strip as the beam vibrates. To dissipate the electrical voltage output from the pickup coil and/or to change the phase of eddy current from the magnetic flux density fluctuation, a shunt circuit is attached. The effective mechanical impedance for the magmetostrictive shunt circuit is derived in a model. The effectiveness of a series L-R and L-C shunt circuit is demonstrated theoretically and experimentally. The non-linear model parameters, which include the mechanical-magnetic coupling factors, alpha and alpha(T), and the permeability of galfenol, beta, are extracted from experimental measurement. The shunted magmetostrictive damping model of both resistive and capacitance shunt cases compare well with the experimental results. C1 US Army Res Lab, Vehicle Technol Directorate, Aberdeen Proving Ground, MD 21005 USA. RP Yoo, J (reprint author), US Army Res Lab, Vehicle Technol Directorate, Aberdeen Proving Ground, MD 21005 USA. NR 6 TC 0 Z9 0 U1 1 U2 2 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-4614-8 PY 2014 AR V001T03A030 PG 7 WC Engineering, Mechanical; Materials Science, Multidisciplinary SC Engineering; Materials Science GA BD4NY UT WOS:000360948000065 ER PT B AU Fujamade, J Williams, F Myers, O Plastied, B Bahoura, M Hall, A Riddick, J AF Fujamade, Johnson Williams, Frances Myers, Oliver Plastied, Brandon Bahoura, Messaoud Hall, Asha Riddick, Jaret GP ASME TI DESIGN AND FABRICATION OF A FUNCTIONALLY MODIFIED BIMORPH ACTUATOR SO PROCEEDINGS OF THE ASME CONFERENCE ON SMART MATERIALS ADAPTIVE STRUCTURES AND INTELLIGENT SYSTEMS, 2014, VOL 2 LA English DT Proceedings Paper CT 7th Annual ASME Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS) CY SEP 08-10, 2014 CL Newport, RI SP ASME, Aerospace Div AB In recent years, the use of microelectromechanical systems (MEMS) devices has led to high performing actuators for various applications, including unmanned air vehicles (UAVs) for defense applications. The incorporation of MEMS technology in this field has resulted in miniaturized UAVs with the capability of carrying out sophisticated reconnaissance and relaying real time information remotely; however, maneuverability of these devices around obstacles is still a challenge. This paper presents the design and fabrication of a functionally modified bimorph actuator with enhanced UAV aerodynamics and maneuverability. The actuator is a metal-based MEMS device consisting of stainless steel, lead zirconate titanate (PZT), and titanium/platinum electrodes. COMSOL analysis was performed to examine optimal device design parameters and is presented in this paper. The design consists of off-axis PZT segments on a bimorph PZT layer which results in bend twist coupling. A detailed description of the fabrication process flow developed based on the optimization of the device design is also given. MEMS processing technology was incorporated to produce a torsional cantilever beam that produces angular and linear displacement for superior UAV maneuverability and its performance is also presented in this paper. C1 [Fujamade, Johnson] Norfolk State Univ, Dept Engn, Norfolk, VA 23504 USA. [Williams, Frances; Bahoura, Messaoud] Norfolk State Univ, Dept Engn, Ctr Mat Res, Norfolk, VA USA. [Myers, Oliver; Plastied, Brandon] Mississippi State Univ, Dept Mech Engn, Mississippi State, MS 39762 USA. [Hall, Asha; Riddick, Jaret] US Army Res Lab, Aberdeen Proving Ground, MD USA. RP Fujamade, J (reprint author), Norfolk State Univ, Dept Engn, Norfolk, VA 23504 USA. NR 10 TC 0 Z9 0 U1 0 U2 3 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-4615-5 PY 2014 AR V002T04A019 PG 5 WC Engineering, Mechanical; Materials Science, Multidisciplinary SC Engineering; Materials Science GA BD4NZ UT WOS:000360949200038 ER PT B AU Zheng, ZL Joshi, U Henein, N Sattler, E AF Zheng, Ziliang Joshi, Umashankar Henein, Naeim Sattler, Eric GP ASME TI Effect of Cetane Improver on Combustion and Emission Characteristics of Coal-derived Sasol IPK in a Single Cylinder Diesel Engine SO PROCEEDINGS OF THE ASME INTERNAL COMBUSTION ENGINE DIVISION, FALL TECHNICAL CONFERENCE, 2014, VOL 1 LA English DT Proceedings Paper CT ASME Internal Combustion Engine Division Fall Technical Conference CY OCT 19-22, 2014 CL Columbus, IN SP ASME, Internal Combust Engine Div, Cummins Inc ID NUMBER; FUEL; PERFORMANCE; BLEND AB Sasol IPK is a coal-derived synthetic fuel under consideration as a blending stock with JP-8 for use in military ground vehicles. Since Sasol IPK is a low ignition quality fuel with Derived Cetane Number (DCN) of 31, there is a need to improve its ignition quality. This paper investigates the effect of adding different amounts of Lubrizol 8090 cetane improver to Sasol IPK on increasing its DCN. The experimental investigation was conducted in a single-cylinder research type diesel engine. The engine is equipped with a common rail injection system and an open Engine Control Unit (ECU). Experiments covered different injection pressures and intake air temperatures. Analysis of test results was made to determine the effect of cetane improver percentage in the coal-derived Sasol IPK blend on autoignition, combustion and emissions of carbon monoxide (CO), total unburned hydrocarbon (HC), oxides of nitrogen (NOx), and particulate matter (PM). In addition, the effect of cetane improver on the apparent activation energy of the global autoignition reactions was determined. C1 [Zheng, Ziliang; Joshi, Umashankar; Henein, Naeim] Wayne State Univ, Detroit, MI 48202 USA. [Sattler, Eric] US Army RDECOM TARDEC, Warren, MI USA. RP Zheng, ZL (reprint author), Wayne State Univ, Detroit, MI 48202 USA. NR 44 TC 0 Z9 0 U1 1 U2 2 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-4616-2 PY 2014 AR V001T02A009 PG 14 WC Engineering, Mechanical SC Engineering GA BD4AW UT WOS:000360415300019 ER PT B AU Sharar, DJ Bergles, AE Jankowski, NR Bar-Cohen, A AF Sharar, Darin J. Bergles, Arthur E. Jankowski, Nicholas R. Bar-Cohen, Avram GP ASME TI NON-INTRUSIVE OPTICAL VALIDATION OF TWO-PHASE FLOW REGIMES IN A SMALL DIAMETER TUBE SO PROCEEDINGS OF THE ASME 12TH INTERNATIONAL CONFERENCE ON NANOCHANNELS, MICROCHANNELS, AND MINICHANNELS, 2014 LA English DT Proceedings Paper CT 12th International Conference on Nanochannels, Microchannels and Minichannels (ICNMM) CY AUG 03-07, 2014 CL Chicago, IL SP ASME ID LIQUID-FILM THICKNESS; PATTERN MAP; HORIZONTAL TUBES; PART I; HEAT-TRANSFER; MICROCHANNELS; VISUALIZATION; EVAPORATION; SMOOTH AB A non-intrusive optical method for two-phase flow pattern identification was developed to validate flow regime maps for two-phase adiabatic flow in a small diameter tube. Empirical measurements of film thickness have been shown to provide objective identification of the dominant two-phase flow regimes, representing a significant improvement over the traditional use of exclusively visual and verbal descriptions. Use of this technique has shown the Taitel-Dukler, Ullmann-Brauner, and Wojtan et al. phenomenological flow regime mapping methodologies to be applicable, with varying accuracy, to small diameter two-phase flow. C1 [Sharar, Darin J.] Gen Tech Serv LLC, Wall, NJ 07719 USA. [Bergles, Arthur E.; Bar-Cohen, Avram] Univ Maryland, College Pk, MD 20742 USA. [Jankowski, Nicholas R.] US Army Res Lab, Adelphi, MD USA. RP Sharar, DJ (reprint author), Gen Tech Serv LLC, Wall, NJ 07719 USA. NR 31 TC 0 Z9 0 U1 1 U2 2 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-4627-8 PY 2014 AR V001T03A016 PG 11 WC Engineering, Mechanical; Nanoscience & Nanotechnology SC Engineering; Science & Technology - Other Topics GA BD4DD UT WOS:000360511900028 ER PT B AU Recchia, SS Pelegri, A Clawson, JK Sahin, K Chasiotis, I Zheng, J AF Recchia, Stephen S. Pelegri, Assimina Clawson, Jan K. Sahin, Korhan Chasiotis, Ioannis Zheng, James GP ASME TI A HIERARCHICAL MODEL FOR KEVLAR FIBER FAILURE SO PROCEEDINGS OF THE ASME INTERNATIONAL MECHANICAL ENGINEERING CONGRESS AND EXPOSITION, 2013, VOL 9 LA English DT Proceedings Paper CT ASME International Mechanical Engineering Congress and Exposition (IMECE2013) CY NOV 15-21, 2013 CL San Diego, CA SP ASME DE Kevlar PA-49; fibril; micro-fibril; nano-fibril; finite element analysis; cohesive contact AB Advances in materials characterization at the submicron and the nano-scales have progressed in the last decade. At the same time, computational capability for finite element analyses are also improving through technological developments in parallel computing. However, large computational models of nanostructured materials are currently limited by the lack of validation data. The work reported in this paper describes the formulation of a representative nanoscale model for Kevlar fibers based on failure section imaging that captures its fibril and microfibril structure. In this regard, a finite element model that captures the nanoscale structure of Kevlar fibers was developed to predict their macroscale response. Experimental derivation of geometrical parameters and physical properties of fibrils and microfibrils is challenging due to the sensitive nature of polymers. There are several microfibril parameters that reflect into effective fiber response, such as the microfibril constitutive behavior, length, diameter, shape, the interfibril shear and normal strength, and the inter-fibril normal and tangential force decay the after peak strength is achieved. This paper investigates the effect of each of the aforementioned parameters on the initial modulus, yield strength, ultimate strength, and strain rate dependence of Kevlar fibers with 10 mu m average diameter. The sensitivity of the macroscale response to each microfibril parameter can be used to identify areas where experimental information can further enable the predictive capability of the computational model. A parametric study was performed to calculate the effective macroscale fiber response. Subsequent', a local gradient sensitivity method was employed to plot the sensitivity of the fiber response to each microfibril parameter. C1 [Recchia, Stephen S.; Pelegri, Assimina] Rutgers State Univ, Mech & Aerosp Engn, Piscataway, NJ 08854 USA. [Clawson, Jan K.; Sahin, Korhan; Chasiotis, Ioannis] Univ Illinois, Aerosp Engn, Urbana, IL 61801 USA. [Zheng, James] US Army, Program Execut Off, Ft Belvoir, VA USA. RP Pelegri, A (reprint author), Rutgers State Univ, Mech & Aerosp Engn, Piscataway, NJ 08854 USA. EM pelegri@jove.rutgers.edu NR 6 TC 0 Z9 0 U1 1 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5638-3 PY 2014 AR V009T10A063 PG 5 WC Engineering, Mechanical; Materials Science, Multidisciplinary SC Engineering; Materials Science GA BD3WY UT WOS:000360260300063 ER PT B AU Zainuddin, S Tauhid, A Hosur, MV Jeelani, S Kumar, A AF Zainuddin, Shaik Tauhid, Arefin Hosur, Mahesh V. Jeelani, Shaik Kumar, Ashok GP ASME TI Recovery of low-velocity impact properties of glass fiber reinforced composites through self-healing technique SO PROCEEDINGS OF THE ASME INTERNATIONAL MECHANICAL ENGINEERING CONGRESS AND EXPOSITION, 2013, VOL 9 LA English DT Proceedings Paper CT ASME International Mechanical Engineering Congress and Exposition (IMECE2013) CY NOV 15-21, 2013 CL San Diego, CA SP ASME ID POLYMER COMPOSITE; REPAIR; DAMAGE; CRACKS AB In this study, we report the self-healing of e-glass/epoxy composites achieved through embedding self-healing agents (SHA) filled hollow glass fibers (HGFs). At first, catalytic technique was used to fill bonded HGFs with SHA. The HGFs were then laid on e-glass fibers and the laminates were fabricated using vacuum assisted resin molding (VARIM) technique. Low-velocity impact tests at two different energy levels were conducted multiple times in the closest proximity to determine the healing efficiency. Optical microscopic study was done to see the changes in the SHA filled HGFs samples before and after impact. Results showed significant recovery of impact properties with 4.47% lost in peak load after second impact in SHA samples whereas it was 27.7% in control samples. The loss in energy to peak load was 20.44% in SHA filled samples, whereas 41% in control samples. Optical microscopy images showed filling of cracks produced after impact with SHA reflecting the significant recovery of impact properties. C1 [Zainuddin, Shaik; Tauhid, Arefin; Hosur, Mahesh V.; Jeelani, Shaik] Tuskegee Univ, Dept Mat Sci Engn, Tuskegee, AL 36088 USA. [Kumar, Ashok] US Army, Construct Engn Res Lab, Engn Res & Dev Ctr, Champaign, IL 61821 USA. RP Zainuddin, S (reprint author), Tuskegee Univ, Dept Mat Sci Engn, Tuskegee, AL 36088 USA. EM szainuddin@mytu.tuskegee.edu; szainuddin@mytu.tuskegee.edu; szainuddin@mytu.tuskegee.edu; szainuddin@mytu.tuskegee.edu NR 21 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5638-3 PY 2014 AR V009T10A010 PG 8 WC Engineering, Mechanical; Materials Science, Multidisciplinary SC Engineering; Materials Science GA BD3WY UT WOS:000360260300010 ER PT B AU Boteler, L Smith, A AF Boteler, Lauren Smith, Andrew GP ASME TI 3D THERMAL RESISTANCE NETWORK METHOD FOR THE DESIGN OF HIGHLY INTEGRATED PACKAGES SO PROCEEDINGS OF THE ASME SUMMER HEAT TRANSFER CONFERENCE - 2013, VOL 3 LA English DT Proceedings Paper CT ASME Summer Heat Transfer Conference (SHTC) CY JUL 14-19, 2013 CL Univ Minnesota, Minneapolis, MN SP ASME, Heat Transfer Div HO Univ Minnesota AB There is a continual market pull in the electronics industry for smaller products with more capabilities, creating a growing need for 3D stacked electronics. This work presents a generic, easy to use approach, to estimate the thermal performance in a generic NxMxP stack using 3D heterogeneous integrated packaging (3D HIP) approach as a baseline. 3D HIP is a microfabrication packaging technology that helps facilitate chip stacking. While this work is demonstrated utilizing the 3D HIP geometry, the technique is easily adapted to most packaging approaches, both 3D and planar. A low order model has been developed with a combination numerical-analytical approach and a 3D resistor network to estimate the chip temperatures. The resistor network solves quickly in MATLAB, enabling fast, iterative thermal analyses and design through the parametric studies of the chip dimensions, number of chips, chip layout, material types, cooling solutions, etc. The model has been validated against full 3D numerical models in COMSOL for a number of conditions including variation of chip dimensions, substrate thickness, number of chips, and material types. The temperature difference between the resistor network model and the COMSOL model was always within 5%. This method can be utilized to identify potential cooling approaches based on the power dissipation per chip and the packaging approach and also to determine the maximum temperatures of each chip. The code achieves significant time saving as compared to full FEA models while providing similar results. C1 [Boteler, Lauren] US Army Res Lab, Adelphi, MD 20783 USA. [Smith, Andrew] US Naval Acad, Annapolis, MD 21402 USA. RP Boteler, L (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. NR 8 TC 0 Z9 0 U1 1 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5549-2 PY 2014 AR V003T10A009 PG 9 WC Thermodynamics; Engineering, Mechanical SC Thermodynamics; Engineering GA BD4AT UT WOS:000360415100032 ER PT B AU Smith, AN Jankowski, N Boteler, L Meyer, C AF Smith, Andrew N. Jankowski, Nicholas Boteler, Lauren Meyer, Christopher GP ASME TI INTERFACIAL RESISTANCE MEASUREMENT OF HIGH PERFORMANCE THERMAL INTERFACE MATERIALS SO PROCEEDINGS OF THE ASME SUMMER HEAT TRANSFER CONFERENCE - 2013, VOL 3 LA English DT Proceedings Paper CT ASME Summer Heat Transfer Conference (SHTC) CY JUL 14-19, 2013 CL Univ Minnesota, Minneapolis, MN SP ASME, Heat Transfer Div HO Univ Minnesota ID CARBON NANOTUBE ARRAYS; NANOCOMPOSITES AB Advancements in thermal interface materials have reached the resolution limit of typical ASTM D5470 based testers, which is around +/-1x10(-6) m(2)K/W. As the interfacial resistance is reduced, the temperature difference at the interface decreases and ultimately becomes difficult to measure. Standard ASTM testers utilize precise temperature sensors and knowledge of the thermal conductivity of the heat meter bar to resolve the temperature difference at the interface. It is difficult to resolve interface resistances on the order of 1x10(-6) m(2)K/W, even when precision RTDs with a resolution of +/-0.001 degrees C are utilized, as the location uncertainty of the sensor can become important. Increasing the temperature difference across the interface is necessary for further improvement in the resolution. This work presents a miniature ASTM type tester that was developed to address the resolution limits of standard testers by reducing the heat meter bar thickness, using a chip resistor as the heater element, and using an IR camera to measure the temperature gradient along the meter bar. Reducing the length of the heat meter bars reduces the overall resistance, and increases the resistance of the interface relative to that of the meter bars. Because of the reduced size scale of the miniature tester, measurement of the temperature profile using the typical ASTM approach of embedding temperature probes along the length of the meter bar was not feasible but instead was achieved using a relatively inexpensive uncooled long wavelength infrared camera with a microscope attachment in order to focus down to 100 microns. Although the IR camera increases the uncertainty of the measured temperatures, this method is shown to measure a thermal interfacial resistance of 1.45x10(-6) m(2)K/W with an uncertainty of +/-1.1 x10(-7) m(2)K/W, where the sample interface was a 2 mil AuSn preform soldered interface. C1 [Smith, Andrew N.] US Naval Acad, Annapolis, MD 21402 USA. [Jankowski, Nicholas; Boteler, Lauren; Meyer, Christopher] US Army Res Lab, Adelphi, MD 20783 USA. RP Smith, AN (reprint author), US Naval Acad, Annapolis, MD 21402 USA. NR 17 TC 0 Z9 0 U1 2 U2 3 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5549-2 PY 2014 AR V003T10A003 PG 7 WC Thermodynamics; Engineering, Mechanical SC Thermodynamics; Engineering GA BD4AT UT WOS:000360415100026 ER PT S AU DeCostanza, AH DiRosa, GA Jimenez-Rodriguez, M Cianciolo, AT AF DeCostanza, Arwen H. DiRosa, Gia A. Jimenez-Rodriguez, Miliani Cianciolo, Anna T. BE Shuffler, ML Rico, R Salas, E TI NO MISSION TOO DIFFICULT: ARMY UNITS WITHIN EXPONENTIALLY COMPLEX MULTITEAM SYSTEMS SO PUSHING THE BOUNDARIES: MULTITEAM SYSTEMS IN RESEARCH AND PRACTICE SE Research on Managing Groups and Teams LA English DT Article; Book Chapter DE Multiteam system; complex teams; meta-system; Army; military; Brigade Combat Team ID PERSPECTIVE; FAULTLINES AB Purpose - In this chapter, we raise awareness of the larger network in which multiteam systems (MTSs) are situated. We posit that in the complex operations conducted by military units, MTSs are not isolated entities, but rather exist in exponentially complex systems that include additional challenges for both research and practice. Approach - An operational example involving an Army Brigade Combat Team Headquarters is presented to explain the details of the exponentially complex MTSs inherent in military operations, raise awareness about challenges that plague successful mission accomplishment, and discuss the way forward for research and practice. Findings - The Army Brigade Combat Team Headquarters is characterized as a traditional MTS, embedded in a system of hierarchical MTSs, further embedded within a parallel structure of MTSs. Challenges inherent in these organizational structures provide direction for research and practice to address the exponentially complex meta-systems that are prevalent throughout the military. Value - While researchers have begun to address teams existing in larger networks, or MTSs (Mathieu, Marks, & Zaccaro, 2001), much of the existing research is based on small or isolated systems. As a result, our understanding of the meta-systems in which many of these MTSs exist is limited. This chapter provides concrete examples of an exponentially complex MTS within a military environment and highlights challenges to be addressed in both research and practice. C1 [DeCostanza, Arwen H.] US Army Res Inst Behav & Social Sci, Aberdeen Proving Ground, MD 21005 USA. [DiRosa, Gia A.; Jimenez-Rodriguez, Miliani] US Army Res Inst Behav & Social Sci, Ft Belvoir, VA USA. [Cianciolo, Anna T.] So Illinois Univ, Sch Med, Dept Med Educ, Springfield, IL USA. RP DeCostanza, AH (reprint author), US Army Res Inst Behav & Social Sci, Aberdeen Proving Ground, MD 21005 USA. NR 22 TC 1 Z9 1 U1 0 U2 1 PU EMERALD GROUP PUBLISHING LTD PI BINGLEY PA HOWARD HOUSE, WAGON LANE, BINGLEY, W YORKSHIRE BD16 1WA, ENGLAND SN 1534-0856 BN 978-1-78350-314-8; 978-1-78350-313-1 J9 RES MANAG GROUP TEAM PY 2014 VL 16 BP 61 EP 76 DI 10.1108/S1534-085620140000016003 D2 10.1108/S1534-0856201416 PG 16 WC Psychology, Applied; Management SC Psychology; Business & Economics GA BD1GK UT WOS:000358000800004 ER PT S AU Huang, C Zhu, SC Erbacher, R AF Huang, Chu Zhu, Sencun Erbacher, Robert BE Atluri, V Pernul, G TI Toward Software Diversity in Heterogeneous Networked Systems SO DATA AND APPLICATIONS SECURITY AND PRIVACY XXVIII SE Lecture Notes in Computer Science LA English DT Proceedings Paper CT 28th Annual IFIP WG 11.3 Working Conference on Data and Applications Security and Privacy (DBSEC) CY JUL 14-16, 2014 CL Vienna, AUSTRIA SP IFIP WG 11 3 ID CHROMATIC NUMBER; GRAPHS; RISKS AB When there are either design or implementation flaws, a homogeneous architecture is likely to be disrupted entirely by a single attack (e.g., a worm) that exploits its vulnerability. Following the survivability through heterogeneity philosophy, we present a novel approach to improving survivability of networked systems by adopting the technique of software diversity. Specifically, we design an efficient algorithm to select and deploy a set of off-the-shelf software to hosts in a networked system, such that the number and types of vulnerabilities presented on one host would be different from that on its neighboring nodes. In this way, we are able to contain a worm in an isolated "island". This algorithm addresses software assignment problem in more complex scenarios by taking into consideration practical constraints, e.g., hosts may have diverse requirements based on different system prerequisites. We evaluate the performance of our algorithm through simulations on both simple and complex system models. The results confirm the effectiveness and scalability of our algorithm. C1 [Huang, Chu; Zhu, Sencun] Penn State Univ, Sch Informat Sci & Technol, University Pk, PA 16802 USA. [Zhu, Sencun] Penn State Univ, Dept Comp Sci & Engn, University Pk, PA 16802 USA. [Erbacher, Robert] US Army Res Lab ARL, Adelphi, MD USA. RP Huang, C (reprint author), Penn State Univ, Sch Informat Sci & Technol, University Pk, PA 16802 USA. EM cuh171@psu.edu; szhu@cse.psu.edu; robert.f.erbacher.civ@mail.mil NR 23 TC 1 Z9 1 U1 0 U2 1 PU SPRINGER-VERLAG BERLIN PI BERLIN PA HEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY SN 0302-9743 BN 978-3-662-43936-4; 978-3-662-43935-7 J9 LECT NOTES COMPUT SC PY 2014 VL 8566 BP 114 EP 129 PG 16 WC Computer Science, Information Systems; Computer Science, Theory & Methods SC Computer Science GA BD3TY UT WOS:000360152700008 ER PT J AU Voss, C Tratz, S Laoudi, J Briesch, D AF Voss, Clare Tratz, Stephen Laoudi, Jamal Briesch, Douglas BE Calzolari, N Choukri, K Declerck, T Loftsson, H Maegaard, B Mariani, J Moreno, A Odijk, J Piperidis, S TI Finding Romanized Arabic Dialect in Code-Mixed Tweets SO LREC 2014 - NINTH INTERNATIONAL CONFERENCE ON LANGUAGE RESOURCES AND EVALUATION LA English DT Proceedings Paper CT 9th International Conference on Language Resources and Evaluation (LREC) CY MAY 26-31, 2014 CL Reykjavik, ICELAND SP Holmes Semant Solut, European Media Lab GmBH, EML, VoiceBox Technologies, KDICTIONARIES DE language identification; code mixing; Arabic dialect; social media AB Recent computational work on Arabic dialect identification has focused primarily on building and annotating corpora written in Arabic script. Arabic dialects however also appear written in Roman script, especially in social media. This paper describes our recent work developing tweet corpora and a token-level classifier that identifies a romanized Arabic dialect and distinguishes it from French and English in tweets. We focus on Moroccan Darija, one of several spoken vernaculars in the family of Maghrebi Arabic dialects. Even given noisy, code-mixed tweets, the classifier achieved token-level recall of 93.2% on romanized Arabic dialect, 83.2% on English, and 90.1% on French. The classifier, now integrated into our tweet conversation annotation tool (Tratz et al. 2013), has semi-automated the construction of a romanized Arabic-dialect lexicon. Two datasets, a full list of Moroccan Darija surface token forms and a table of lexical entries derived from this list with spelling variants, as extracted from our tweet corpus collection, will be made available in the LRE MAP. C1 [Voss, Clare; Tratz, Stephen; Briesch, Douglas] Army Res Lab, Adelphi, MD 20783 USA. [Laoudi, Jamal] ARTI, Fairfax, VA 22030 USA. RP Voss, C (reprint author), Army Res Lab, Adelphi, MD 20783 USA. EM clare.r.voss.civ@mail.mil; stephen.c.tratz.civ@mail.mil; jamal.laoudi.ctr@mail.mil; douglas.m.briesch.civ@mail.mil NR 8 TC 0 Z9 0 U1 0 U2 0 PU EUROPEAN LANGUAGE RESOURCES ASSOC-ELRA PI PARIS PA 55-57, RUE BRILLAT-SAVARIN, PARIS, 75013, FRANCE BN 978-2-9517408-8-4 PY 2014 BP 2249 EP 2253 PG 5 WC Linguistics; Language & Linguistics SC Linguistics GA BC8FH UT WOS:000355611003135 ER PT B AU Hinz, BJ Muci-Kuchler, KH Smith, PM AF Hinz, Brandon J. Muci-Kuechler, Karim H. Smith, Pauline M. GP ASME TI DISTRIBUTION OF BACTERIA IN SIMPLIFIED SURROGATE EXTREMITIES SHOT WITH SMALL CALIBER PROJECTILES SO PROCEEDINGS OF THE ASME INTERNATIONAL MECHANICAL ENGINEERING CONGRESS AND EXPOSITION, 2013, VOL 3A LA English DT Proceedings Paper CT ASME International Mechanical Engineering Congress and Exposition (IMECE2013) CY NOV 15-21, 2013 CL San Diego, CA SP ASME DE Contamination of ballistic wounds; bacteria distribution in wounds; projectile injury; Escherichia coli K-12; ballistic gelatin ID GUNSHOT INJURIES; BULLET PATH; INFECTIONS; WOUNDS; MANAGEMENT; SKIN; CONTAMINATION; BATTLEFIELD; DEBRIDEMENT; GELATIN AB Experiments were conducted to determine bacteria distribution trends in wound cavities of simplified surrogate extremities shot using small caliber projectiles. Two different shapes of targets, cylindrical and square, were used in this study. Cylindrical targets are more representative of an extremity but create difficulties while conducting tests due to inconsistent cavity lengths and optical distortions. Square targets, which are not as susceptible to the problems mentioned above, could be used in place of cylindrical ones if their shape does not significantly affect the distribution of bacteria within the wound cavity. Surface contamination of the targets in the experiments was represented using a circular piece of filter paper moistened with a solution with a known amount of Escherichia coli strain K-12. The projectiles used were 11.43-mm (0.45-in) caliber round nose projectiles shot from a commercially available air rifle. The permanent cavities were extracted from the targets and sliced into small, evenly spaced segments and the area surrounding the permanent cavities was removed with a biopsy punch. The radial tears that were made by the formation of the temporary cavity and surround the permanent cavity were removed using a scalpel. The permanent cavity and radial tears for each section were processed and plated on agar plates. Commercial software was used to count the number of colony forming units on each plate and the percentage of the total bacterial colony count per segment was determined. High speed video and motion analysis software was used to qualitatively and quantitatively compare the temporary cavities in the cylindrical and square targets. The data from the experiments showed that the bacteria distribution trends for the cylindrical and square targets were similar even though the maximum openings of the temporary cavity at the entrance and exit locations were higher for the cylindrical ones. For both target shapes, the bacterium was evenly distributed between the permanent cavity and the radial tears in the middle sections of the "wound tracks." In addition, significantly higher amounts of bacterium were found in the entrance and exit segments compared with the rest of the segments in the "wound tracks". C1 [Hinz, Brandon J.; Muci-Kuechler, Karim H.] South Dakota Sch Mines & Technol, Expt & Computat Mech Lab, Dept Mech Engn, Rapid City, SD 57701 USA. [Smith, Pauline M.] US Army Res Lab, Weap & Mat Directorate, Aberdeen Proving Ground, MD 21005 USA. RP Hinz, BJ (reprint author), South Dakota Sch Mines & Technol, Expt & Computat Mech Lab, Dept Mech Engn, 501 East St Joseph St, Rapid City, SD 57701 USA. EM Karim.Muci@sdsmt.edu; Pauline.m.smith.civ@mail.mil NR 41 TC 0 Z9 0 U1 1 U2 3 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5621-5 PY 2014 AR V03AT03A012 PG 11 WC Biophysics; Engineering, Biomedical; Engineering, Mechanical SC Biophysics; Engineering GA BD3HE UT WOS:000359682400012 ER PT B AU Ostertag, MH Kenyon, M Borkholder, DA Lee, G da Silva, LU Kamimori, G AF Ostertag, Michael H. Kenyon, Matthew Borkholder, David A. Lee, General da Silva, Lt. Uade Kamimori, Gary GP ASME TI THE BLAST GAUGE(TM) SYSTEM AS A RESEARCH TOOL TO QUANTIFY BLAST OVERPRESSURE IN COMPLEX ENVIRONMENTS SO PROCEEDINGS OF THE ASME INTERNATIONAL MECHANICAL ENGINEERING CONGRESS AND EXPOSITION, 2013, VOL 3A LA English DT Proceedings Paper CT ASME International Mechanical Engineering Congress and Exposition (IMECE2013) CY NOV 15-21, 2013 CL San Diego, CA SP ASME DE Blast dosimeter; Pressure sensor; Blast modeling; Blast overpressure; Primary blast injury; Breaching; Tactical Entry AB Tactical officers and military personnel who, train in explosive entry techniques regularly put themselves at risk of blast exposure. The overpressure conditions in complex military and law enforcement environments, such as interior doors, hallways, and stairwells, cannot be accurately predicted by standard blast models which were developed from outdoor, free-field blasts. In both training and operations, small, low-cost blast overpressure sensors would provide the benefit of tracking exposure levels of at-risk individuals. The sensors would allow, for the first time, direct determination of safe stand-off distances and positioning for personnel during explosive breaching. Overpressure, impulse, and acceleration data has been captured for a series of interior and exterior blasts, demonstrating the utility of the Blast Gauge system as a training and research tool to quantify blast overpressure in complex environments. C1 [Ostertag, Michael H.; Kenyon, Matthew] BlackBox Biometr Inc, Rochester, NY 14623 USA. [Borkholder, David A.] BlackBox Biometr Inc, Rochester Inst Technol, Rochester, NY USA. [Lee, General; Kamimori, Gary] Walter Reed Army Inst Res, Silver Spring, MD USA. [da Silva, Lt. Uade] Naval Med Res Ctr, Silver Spring, MD USA. RP Ostertag, MH (reprint author), BlackBox Biometr Inc, Rochester, NY 14623 USA. NR 2 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5621-5 PY 2014 AR V03AT03A017 PG 2 WC Biophysics; Engineering, Biomedical; Engineering, Mechanical SC Biophysics; Engineering GA BD3HE UT WOS:000359682400017 ER PT B AU Selvan, V Halls, V Zheng, J Chandra, N AF Selvan, Veera Halls, Virginia Zheng, James Chandra, Namas GP ASME TI COMPARING THE BEHAVIOR OF HOMOGENEOUS VS. FLUID FILLED SOLID HEADFORMS UNDER BLUNT IMPACT LOADING CONDITIONS SO PROCEEDINGS OF THE ASME INTERNATIONAL MECHANICAL ENGINEERING CONGRESS AND EXPOSITION, 2013, VOL 3A LA English DT Proceedings Paper CT ASME International Mechanical Engineering Congress and Exposition (IMECE2013) CY NOV 15-21, 2013 CL San Diego, CA SP ASME ID COLLEGIATE FOOTBALL PLAYERS; HEAD-INJURIES; PROFESSIONAL FOOTBALL; BIOMECHANICS; CONCUSSION; TRAUMA; SOCCER; NECK AB A single point acceleration measurement at the center of gravity (C.G) of the rigid headform has been typically used to assess the head injuries under the blunt loading conditions. The head protective equipment (e.g. Helmets) used in sports, vehicles and defense fields are developed and tested based on this single point acceleration. This raises two critical questions; 1) can a homogeneous rigid headform represent the heterogeneous skull-brain complex; 2) If not, which is the critical point of measurement in the compliant headform. To answer these questions, compliant (acrylic gel complex) and rigid (aluminum body) head surrogates with an identical mass are subjected to similar blunt loading conditions. Target surfaces of different stiffness and an impact velocity of 1 m/s are employed to evaluate the critical difference in the head surrogates. Acceleration (C.G) and shell strain (impact location) in the compliant surrogate and acceleration (C.G) and the impact force in the rigid surrogate are experimentally measured. Experimental and computational studies illustrate that the acceleration field in the gel-filled case varies from coup to counter-coup region; however, the acceleration field in the rigid headform is uniform. The variation in the acceleration field is influenced by the shell deformation that in turn depends on the stiffness of the target surface. In deformable target surfaces, the acceleration and head injury criterion (HIC) values are higher in the compliant surrogate than the rigid surrogate; the effect is reversed for rigid target surfaces. C1 [Selvan, Veera] Univ Nebraska, Dept Mech & Mat Engn, Lincoln, NE 68583 USA. [Halls, Virginia; Zheng, James] US Army, Program Execut Off Soldier, Ft Belvoir, VA USA. [Chandra, Namas] New Jersey Inst Technol, Dept Biomed Engn, Newark, NJ 07102 USA. [Chandra, Namas] Univ Nebraska, Lincoln, NE USA. RP Selvan, V (reprint author), Univ Nebraska, Dept Mech & Mat Engn, Lincoln, NE 68583 USA. NR 36 TC 0 Z9 0 U1 1 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5621-5 PY 2014 AR V03AT03A015 PG 8 WC Biophysics; Engineering, Biomedical; Engineering, Mechanical SC Biophysics; Engineering GA BD3HE UT WOS:000359682400015 ER PT B AU Zhang, TG Satapathy, SS Dagro, AM Mckee, PJ AF Zhang, Timothy G. Satapathy, Sikhanda S. Dagro, Amy M. Mckee, Philip J. GP ASME TI NUMERICAL STUDY OF HEAD/HELMET INTERACTION DUE TO BLAST LOADING SO PROCEEDINGS OF THE ASME INTERNATIONAL MECHANICAL ENGINEERING CONGRESS AND EXPOSITION, 2013, VOL 3A LA English DT Proceedings Paper CT ASME International Mechanical Engineering Congress and Exposition (IMECE2013) CY NOV 15-21, 2013 CL San Diego, CA SP ASME ID CAVITATION; IMPACT AB Recent wars have heightened the need to better protect dismounted soldiers against emerging blast and ballistic threats. Traumatic Brain Injury (TBI) due to blast and ballistic loading has been a subject of many recent studies. In this paper, we report a numerical study to understand the effects of load transmitted through a combat helmet and pad system to the head and eventually to the brain during a blast event. The ALE module in LS-DYNA was used to model the interactions between fluid (air) and the structure (helmet/head assembly). The geometry model for the head was generated from the MRI scan of a human head. For computational simplicity, four major components of the head are modeled: skin, bone, cerebrospinal fluid (CSF) and brain. A spherical shape blast wave was generated by using a spherical shell air zone surrounding the helmet/head structure:A numerical evaluation of boundary conditions and numerical algorithm to capture the wave transmission was carried out first in a simpler geometry. The ConWep function was used to apply blast pressure to the 3D model. The blast pressure amplitude was found to reduce as it propagated through the foam pads, indicating the latter's utility in mitigating blast effects. It is also shown that the blast loads are only partially transmitted to the head. In the calculation where foam pads were not used, the pressure in the skin was found to be higher due to the underwash effect in the gap between the helmet and skin, which amplified the blast pressure. C1 [Zhang, Timothy G.] Bowhead Sci & Technol, Belcamp, MD 21017 USA. [Satapathy, Sikhanda S.; Dagro, Amy M.] US Army Res Lab, Aberdeen Proving Ground, MD USA. [Mckee, Philip J.] Dynam Sci Inc, Aberdeen, MD USA. RP Zhang, TG (reprint author), Bowhead Sci & Technol, Belcamp, MD 21017 USA. RI Satapathy, Sikhanda/L-5264-2015 NR 16 TC 0 Z9 0 U1 1 U2 3 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5621-5 PY 2014 AR V03AT03A004 PG 11 WC Biophysics; Engineering, Biomedical; Engineering, Mechanical SC Biophysics; Engineering GA BD3HE UT WOS:000359682400004 ER PT B AU Eichner, DJ AF Eichner, Daniel J. GP ASME TI UTILIZING X-RAY COMPUTED TOMOGRAPHY IN SPRAY NOZZLE ANALYSIS SO PROCEEDINGS OF THE ASME INTERNATIONAL MECHANICAL ENGINEERING CONGRESS AND EXPOSITION, 2013, VOL 7B LA English DT Proceedings Paper CT ASME International Mechanical Engineering Congress and Exposition (IMECE2013) CY NOV 15-21, 2013 CL San Diego, CA SP ASME AB Characterizing the near-nozzle region of liquid sprays is a challenge for spray system designers due to the lack of optical accessibility in this dense region of the spray using traditional imaging techniques. A novel diagnostic technique, utilizing standard medical X-ray computed tomography equipment, is developed to investigate the time-averaged mass distribution of the liquid phase of the spray within 50 diameters downstream of the nozzle exit. Reconstructed images provide the three-dimensional concentration of the liquid phase of the spray. Analysis of several iodine- based liquids was conducted based on physical properties and non-dimensional parameters. To compare a general procedural approach for obtaining the three-dimensional concentration field from an X-ray CT system, a traditional optical analysis was conducted using Mie Scattering and Shadowgraphy. Results for a full-cone pressure swirl atomizer with an orifice of 0.79 mm are presented for both water and Povidone Iodide. Qualitative and quantitative results gave insight into the spray cone angle, atomization of the spray, arid the droplet size and velocity distribution 50 diameters downstream. The water (Re approximate to 20,000) atomizes further upstream than the Povidone Iodide (Re approximate to 6,100) with a larger spray cone angle. The images obtained from the traditional optical techniques were qualitatively compared to the new diagnostic technique. The three dimensional mass distribution of Hypaque from a 0.79 mm nozzle has a number of similarities with the water spray, measured with an isotropic spatial resolution of 200 mu m and noise per voxel less than 0.02 g/cm(3). C1 US Mil Acad, West Point, NY 10996 USA. RP Eichner, DJ (reprint author), US Mil Acad, West Point, NY 10996 USA. EM Daniel.eichner@usma.edu NR 9 TC 0 Z9 0 U1 1 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5632-1 PY 2014 AR V07BT08A073 PG 9 WC Engineering, Mechanical SC Engineering GA BD3NW UT WOS:000359960200073 ER PT B AU Hadim, H Blecker, K AF Hadim, H. Blecker, K. GP ASME TI A NUMERICAL STUDY OF CONJUGATE HEAT TRANSFER BY NATURAL CONVECTION AND SURFACE RADIATION IN A SQUARE ENCLOSURE WITH THICK ADIABATIC WALLS SO PROCEEDINGS OF THE ASME INTERNATIONAL MECHANICAL ENGINEERING CONGRESS AND EXPOSITION, 2013, VOL 8A LA English DT Proceedings Paper CT ASME International Mechanical Engineering Congress and Exposition (IMECE2013) CY NOV 15-21, 2013 CL San Diego, CA SP ASME DE conjugate heat transfer; natural convection; thermal radiation; enclosure; conduction ID MIXED CONVECTION; CAVITY; BOUNDARY; STEADY AB A numerical solution of heat transfer by combined natural convection and surface radiation in a square enclosure with thick adiabatic top and bottom walls and isothermal vertical walls is presented. The present model was used to obtain new results with the addition of thermal conduction at the thick top and bottom walls for a thermal conductivity ratio, K=k(solid)/k(fluid), that ranges from 0 to 10, emissivity of the adiabatic walls that ranges from 0 to 1, and the Rayleigh Number that ranges from 10(3) to 10(6). The model was validated by comparing the results to a benchmark solution and other solutions found in the literature. The results showed that with an increase in thermal conductivity ratio, the flow circulation decreases while the average Nusselt Number increases indicating increased heat transfer across the thick walls and the fluid in the corners. The results indicate that while past studies have shown negligible impact of the emissivity of the adiabatic walls on characteristics of the flow and heat transfer within the cavity, when a wall with moderate heat capacity and conductivity is considered, the resulting flow velocity and temperature distribution within the cavity are found to be significantly influenced by the thick wall emissivity. As the conductivity ratio increases this discrepancy between thin and thick walls becomes greater, there is further need for a more complex and accurate model including the thick walls. The results also showed that an increase in the emissivity of the adiabatic walls results in a slight decrease in the average Nusselt Number. C1 [Hadim, H.] Stevens Inst Technol, Hoboken, NJ 07030 USA. [Blecker, K.] US Army, ARDEC, Picatinny Arsenal, NJ USA. RP Hadim, H (reprint author), Stevens Inst Technol, Hoboken, NJ 07030 USA. NR 17 TC 0 Z9 0 U1 1 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5634-5 PY 2014 AR V08AT09A034 PG 7 WC Thermodynamics; Engineering, Mechanical SC Thermodynamics; Engineering GA BD3PX UT WOS:000360032600034 ER PT B AU Zhang, N He, AP Corbino, J Schroeder, P Bolton, J AF Zhang, Ning He, Anpeng Corbino, Jeff Schroeder, Paul Bolton, Johnathan GP ASME TI THE IMPACTS OF CONFINED DISPOSAL FACILITIES ON CALCASIEU SHIP CHANNEL SEDIMENTATION SO PROCEEDINGS OF THE ASME FLUIDS ENGINEERING DIVISION SUMMER MEETING, 2013, VOL 1A: SYMPOSIA LA English DT Proceedings Paper CT ASME Fluids Engineering Division Summer Meeting CY JUL 07-11, 2013 CL Incline Village, NV SP ASME, Fluids Engn Div AB The confined disposal facilities (CDFs) are the areas along Calcasieu Ship Channel to store dredged sediments from the ship channel. As the sediments settle in the CDFs, the low concentration sediment flows are discharged into the open water adjacent to the CDFs. The paper demonstrates flow and sediment transport characteristics in the open water due to the CDF discharge. The sediment distributions in all three dimensions in the water are revealed. The lake current effects were also investigated. A commercial CFD package ANSYS-FLUENT is used to simulate all cases in this study. C1 [Zhang, Ning; He, Anpeng; Bolton, Johnathan] McNeese State Univ, Dept Engn, Lake Charles, LA 70605 USA. [Corbino, Jeff] US Army Corps Engineers, Operat Div, New Orleans Dist, New Orleans, LA USA. [Schroeder, Paul] US Army Corps Engineers, Engn Res & Dev Ctr, Vicksburg, MS USA. RP Zhang, N (reprint author), McNeese State Univ, Dept Engn, Lake Charles, LA 70605 USA. EM nzhang@mcneese.edu NR 4 TC 0 Z9 0 U1 1 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5554-6 PY 2014 AR V01AT03A008 PG 7 WC Engineering, Mechanical; Mechanics; Physics, Fluids & Plasmas SC Engineering; Mechanics; Physics GA BD2PE UT WOS:000359029100023 ER PT B AU Baig, HA Dorman, DB Shivers, BL Breaux-Waltz, A Chancey, VC Winkelstein, BA AF Baig, Hassam A. Dorman, Daniel B. Shivers, Bethany L. Breaux-Waltz, Arlene Chancey, V. Carol Winkelstein, Beth A. GP ASME TI CHARACTERIZATION OF THE FREQUENCY & MUSCLE RESPONSE IN THE LUMBAR & THORACIC SPINES DURING SINUSOIDAL VERTICAL WHOLE BODY VIBRATION SO PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE - 2013, PT B LA English DT Proceedings Paper CT 15th American-Society-Mechanical-Engineering Summer Bioengineering Conference (SBC2013) CY JUN 26-29, 2013 CL Sunriver, OR SP Amer Soc Mech Engn, Bioengineer Div ID EXPOSURE; PAIN C1 [Baig, Hassam A.; Winkelstein, Beth A.] Univ Penn, Dept Bioengn, Spine Pain Res Lab, Philadelphia, PA 19104 USA. [Dorman, Daniel B.; Shivers, Bethany L.; Breaux-Waltz, Arlene; Chancey, V. Carol] US Army Aeromed Res Lab, Injury Biomech Branch, Fort Rucker, AL 36362 USA. RP Baig, HA (reprint author), Univ Penn, Dept Bioengn, Spine Pain Res Lab, Philadelphia, PA 19104 USA. NR 8 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5561-4 PY 2014 AR V01BT61A001 PG 2 WC Biophysics; Engineering, Biomedical SC Biophysics; Engineering GA BD2YI UT WOS:000359389300261 ER PT B AU Bertucci, R Prabhu, R Horstemeyer, MF Sheng, J Liao, J Williams, L AF Bertucci, Robbin Prabhu, R. Horstemeyer, M. F. Sheng, James Liao, Jun Williams, Lakiesha GP ASME TI VALIDATION OF FINITE ELEMENT LOWER EXTREMITY MODEL USING DROP TOWER TESTING SO PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE - 2013, PT B LA English DT Proceedings Paper CT 15th American-Society-Mechanical-Engineering Summer Bioengineering Conference (SBC2013) CY JUN 26-29, 2013 CL Sunriver, OR SP Amer Soc Mech Engn, Bioengineer Div C1 [Sheng, James] US Army TARDEC, Warren, MI USA. NR 4 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5561-4 PY 2014 AR V01BT55A023 PG 2 WC Biophysics; Engineering, Biomedical SC Biophysics; Engineering GA BD2YI UT WOS:000359389300213 ER PT B AU Reilly, MA Sherwood, D Watson, R Gray, W Sponsel, WE Thoe, K Lund, B Glickman, R AF Reilly, Matthew A. Sherwood, Daniel Watson, Richard Gray, Walt Sponsel, William E. Thoe, Kimberly Lund, Brian Glickman, Randolph GP ASME TI MANIFESTATIONS OF PRIMARY BLAST-INDUCED OCULAR TRAUMA SO PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE - 2013, PT B LA English DT Proceedings Paper CT 15th American-Society-Mechanical-Engineering Summer Bioengineering Conference (SBC2013) CY JUN 26-29, 2013 CL Sunriver, OR SP Amer Soc Mech Engn, Bioengineer Div AB Prevalence of ocular trauma in battlefield injury has increased significantly in recent years. The majority of such injuries are due to improvised explosive devices. While impact-induced injuries are relatively well characterized, little is known regarding the effects of primary blast. We exposed porcine eyes to a simulated blast using a shock tube to correlate the blast overpressure with various trauma manifestations. C1 [Reilly, Matthew A.; Sherwood, Daniel; Watson, Richard] Univ Texas San Antonio, Dept Biomed Engn, San Antonio, TX 78249 USA. [Gray, Walt] Univ Texas San Antonio, Dept Geol Sci, San Antonio, TX 78249 USA. [Sponsel, William E.; Thoe, Kimberly] WES Profess Associates, San Antonio, TX 78205 USA. [Lund, Brian] US Army, Inst Surg Res, San Antonio Mil Med Ctr, Ft Sam Houston, TX 78234 USA. [Glickman, Randolph] UT Hlth Sci Ctr, Dept Ophthalmol, San Antonio, TX 78229 USA. RP Reilly, MA (reprint author), Univ Texas San Antonio, Dept Biomed Engn, San Antonio, TX 78249 USA. EM matthew.reilly@utsa.edu; walter.gray@utsa.edu; sponsel@earthlink.net; brian.j.lund@amedd.army.mil; glickman@uthscsa.edu NR 2 TC 0 Z9 0 U1 1 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5561-4 PY 2014 AR V01BT55A019 PG 2 WC Biophysics; Engineering, Biomedical SC Biophysics; Engineering GA BD2YI UT WOS:000359389300209 ER PT B AU Tong, XL Luke, E Remotigue, M Kang, J AF Tong, Xiaoling Luke, Edward Remotigue, Michael Kang, Jian GP ASME TI MULTIPHASE SIMULATIONS OF BLAST-SOIL INTERACTIONS SO PROCEEDINGS OF THE ASME FLUIDS ENGINEERING DIVISION SUMMER MEETING, 2013, VOL 1C: SYMPOSIA LA English DT Proceedings Paper CT ASME Fluids Engineering Division Summer Meeting CY JUL 07-11, 2013 CL Incline Village, NV SP ASME, Fluids Engn Div AB One challenge associated with the simulation of buried detonations involves the treatment of the multiphase flow phenomena related to the soil. At the moment when the soil "shatters" into a dense particulate cloud with detonation products escaping through the soil particles, the continuum model that assumes a single velocity shared by the blast gas and the soil at any given point no longer holds. Instead momentum coupling between the two phases has to be modeled. One characteristic at the stage of soil breaking is that the soil fragments packed in a tight configuration under large pressure provide significant blockage effect characterized by large particle volume fractions. Unfortunately, traditional drag laws do not address the momentum coupling between gas and solid phase under the condition of particle high volume fraction in high speed blast flows. In order to develop a phenomenological drag model to characterize the momentum coupling between the detonation gas and soil fragments when the soil initially breaks into a dense particulate cloud, we conducted a series of numerical simulations on the scale of soil fragments by only considering a small region occupied by a mixture of blast gas and soil fragments (so-called particle-scale simulations). A drag database was constructed based on the drag force collected from the particle-scale simulations under the conditions of various soil volume fractions and particle sizes. A new drag law was developed using data regression technique to characterize the dependency of the drag force exerted on particles as a function of particle volume fraction and Reynolds number based on particle size. The proposed drag law provides satisfactory representations of the simulation data, and converge to traditional drag model for isolated particles when the particle volume fraction approaches to zero. Finally, we applied the new phenomenological drag law in the simulations of buried detonation at the stage of soil breaking, and compared the results with the ones from continuum model in which the gas and the soil are assumed moving. at the same speed. C1 [Tong, Xiaoling] Mississippi State Univ, Ctr Adv Vehicular Syst, Simctr CAVS, Starkville, MS 39759 USA. [Luke, Edward] Mississippi State Univ, Dept Comp Sci, Starkville, MS 39759 USA. [Remotigue, Michael] Mississippi State Univ, Ctr Adv Vehicular Syst, Starkville, MS 39759 USA. [Kang, Jian] US Army RDECOM TARDEC, Warren, MI 48397 USA. RP Tong, XL (reprint author), Mississippi State Univ, Ctr Adv Vehicular Syst, Simctr CAVS, 2 Res Blvd, Starkville, MS 39759 USA. EM xltong@cavs.msstate.edu NR 8 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5556-0 PY 2014 AR V01CT25A005 PG 10 WC Engineering, Mechanical; Mechanics; Physics, Fluids & Plasmas SC Engineering; Mechanics; Physics GA BD2PG UT WOS:000359030900057 ER PT B AU Zheng, ZL Badawy, T Henein, N Sattler, E Johnson, N AF Zheng, Ziliang Badawy, Tamer Henein, Naeim Sattler, Eric Johnson, Nicholas GP ASME TI Effect of Cetane Improver on Autoignition Characteristics of Low Cetane Sasol IPK Using Ignition Quality Tester (IQT) SO PROCEEDINGS OF THE ASME INTERNAL COMBUSTION ENGINE DIVISION FALL TECHNICAL CONFERENCE, 2013, VOL 2: NUMERICAL SIMULATION; ENGINE DESIGN, LUBRICATION, AND APPLICATIONS LA English DT Proceedings Paper CT Fall Technical Conference of the ASME Internal Combustion Engine Division CY OCT 13-16, 2013 CL Dearborn, MI SP ASME, Internal Combust Engine Div ID FUEL; EMISSIONS; PERFORMANCE; NUMBER AB This paper investigates the effect of a cetane improver on the autoignition characteristics of Sasol IPK in the combustion chamber of the Ignition Quality Tester (IQT). The fuel tested was Sasol IPK with a Derived Cetane Number (DCN) of 31, treated with different percentages of Lubrizol 8090 cetane improver ranging from 0.1% to 0.4%. Tests were conducted under steady state conditions at a constant charging pressure of 21 bar. The charge air temperature before fuel injection varied from 778 to 848 K. Accordingly, all the tests were conducted under a constant charge density. The rate of heat release was calculated and analyzed in details, particularly during the autoignition period. In addition, the physical and chemical delay periods were determined by comparing the results of two tests. The first was conducted with fuel injection into air according to ASTM standards where combustion occurred. In the second test, the fuel was injected into the chamber charged with nitrogen. The physical delay is defined as the period of time from start of injection (SOI) to point of inflection (POI), and the chemical delay is defined as the period of time from POI to start of combustion (SOC). Both the physical and chemical delay periods were determined under different charge temperatures. The cetane improver was found to have an effect only on the chemical ID period. In addition, the effect of the cetane improver on the apparent activation energy of the global combustion reactions was determined. The results showed a linear drop in the apparent activation energy with the increase in the percentage of the cetane improver. Moreover, the low temperature (LT) regimes were investigated and found to be presented in base fuel, as well as cetane improver treated fuels. C1 [Zheng, Ziliang; Badawy, Tamer; Henein, Naeim] Wayne State Univ, Detroit, MI 48202 USA. [Sattler, Eric; Johnson, Nicholas] US Army RDECOM TARDEC, Warren, MI USA. RP Zheng, ZL (reprint author), Wayne State Univ, Detroit, MI 48202 USA. NR 40 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5610-9 PY 2014 AR V002T02A002 PG 12 WC Engineering, Mechanical; Mathematics, Applied SC Engineering; Mathematics GA BD2PD UT WOS:000359026600002 ER PT J AU Zaidi, SAR Ghogho, M McLernon, DC Swami, A AF Zaidi, Syed Ali Raza Ghogho, Mounir McLernon, Desmond C. Swami, Ananthram GP IEEE TI Energy Harvesting Empowered Cognitive Metro-cellular Networks SO 2014 1ST INTERNATIONAL WORKSHOP ON COGNITIVE CELLULAR SYSTEMS (CCS) LA English DT Proceedings Paper CT 1st International Workshop on Cognitive Cellular Systems (CCS) CY SEP 02-04, 2014 CL GERMANY DE energy harvesting; cognitive radio; metro-cells; solar irradiance; Hottell's model; Poisson point process; LTE; phantom cell AB Harvesting energy from natural (solar, wind, vibration etc.) and synthesized (microwave power transfer) sources is envisioned as a key enabler for realizing green wireless networks. Energy efficient scheduling is one of the prime objectives of cognitive radio platforms. To that end, in this article, we present a comprehensive analytical framework to characterize the performance of a cognitive metro-cellular network empowered by solar energy harvesting. The proposed model considers both spatial and temporal dynamics of the energy field and the mobile user traffic. Channel uncertainties are also captured in terms of large scale path-loss and small-scale Rayleigh fading. A new metric called 'energy outage probability' which characterizes the self-sustainable operation of the base stations under energy harvesting is proposed and quantified. It is shown that the energy outage probability is strongly coupled with the path-loss exponent, required quality-of-service, base station and user density. Moreover, the energy outage probability varies both on daily and yearly basis depending on the solar geoemtry. It is shown that even in winter time BSs can run for 10-15 hours without any purchase of energy from the power grid. C1 [Zaidi, Syed Ali Raza; Ghogho, Mounir; McLernon, Desmond C.] Univ Leeds, Sch Elect & Elect Engn, Leeds LS2 9JT, W Yorkshire, England. [Ghogho, Mounir] Int Univ Rabat, Rabat, Morocco. [Swami, Ananthram] US Army Res Lab, Adelphi, MD USA. RP Zaidi, SAR (reprint author), Univ Leeds, Sch Elect & Elect Engn, Leeds LS2 9JT, W Yorkshire, England. EM elsarz@leeds.ac.uk; m.ghogho@leeds.ac.uk; d.c.mclernon@leeds.ac.uk NR 23 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA PY 2014 PG 5 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BD2EJ UT WOS:000358693400029 ER PT J AU Ygouf, M Aubailly, M Carhart, GW Liu, JJ AF Ygouf, Marie Aubailly, Mathieu Carhart, Gary W. Liu, J. Jiang GP IEEE TI Wavefront Sensorless Multi-Conjugate Adaptive Optics for Imaging in Deep Atmospheric Turbulence: Preliminary Numerical Analysis SO 2014 IEEE AEROSPACE CONFERENCE LA English DT Proceedings Paper CT IEEE Aerospace Conference CY MAR 01-08, 2014 CL Big Sky, MT SP IEEE ID ANISOPLANATISM; SCINTILLATION; COMPENSATION; SYSTEMS AB This paper deals with the problem of imaging in deep atmospheric turbulence conditions such as the ones encountered in long near-horizontal propagation scenarios. Under such conditions, anisoplanatism as well as the presence of intensity scintillations prevent efficient use of conventional single-wavefront corrector adaptive optics systems. Multi-conjugate adaptive optics (MCAO) techniques have been successfully demonstrated in the field of astronomy to mitigate anisoplanatism effects and improve correction on extended objects in weak atmospheric turbulence conditions. However these techniques typically require the use of several wavefront sensors which increases system complexity, and are impacted by the presence of intensity scintillations. We propose to use a wavefront sensorless MCAO method based solely on the optimization of image quality metrics. In this method, the commands applied to the deformable mirrors are computed from a metric derived directly from the compensated image. The method has the advantage of being more robust to scintillations and does not require wavefront sensors. In this preliminary numerical study, we evaluate the benefit of the MCAO approach in deep turbulence. C1 [Ygouf, Marie; Aubailly, Mathieu] Univ Maryland, Intelligent Opt Lab, College Pk, MD 20742 USA. [Carhart, Gary W.] Army Res Lab, Computat & Informat Sci Directorate, Adelphi, MD 20783 USA. [Liu, J. Jiang] Army Res Lab, Adelphi, MD 20783 USA. RP Ygouf, M (reprint author), Univ Maryland, Intelligent Opt Lab, 5000 Coll Av,Technol Ventures Bldg,Suite 2107, College Pk, MD 20742 USA. EM mygouf@umd.edu; mathieu@umd.edu; gary.w.carhart.civ@mail.mil; jony.j.liu.civ@mail.mil NR 15 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-1622-1 PY 2014 PG 6 WC Engineering, Aerospace; Engineering, Electrical & Electronic SC Engineering GA BC8RQ UT WOS:000356039102065 ER PT B AU Grigolini, P Zare, M Svenkeson, A West, BJ AF Grigolini, Paolo Zare, Marzieh Svenkeson, Adam West, Bruce J. BE Plenz, D Niebur, E TI Neural Dynamics: Criticality, Cooperation, Avalanches, and Entrainment between Complex Networks SO CRITICALITY IN NEURAL SYSTEMS LA English DT Proceedings Paper CT Conference on Criticality in Neural Systems CY APR 30-MAY 01, 2012 CL Natl Inst Hlth, Bethesda, MD HO Natl Inst Hlth ID TIME RANDOM-WALK; EXTENDED CRITICALITY; NEURONAL AVALANCHES; POWER-LAW; SYNCHRONIZATION; BRAIN; MODEL; DIFFUSION C1 [Grigolini, Paolo] Univ N Texas, Ctr Nonlinear Sci, Dept Phys, Denton, TX 76203 USA. [Zare, Marzieh; Svenkeson, Adam] Univ Calif San Diego, BioCircuit Inst, Math & Informat Sci Directorate, Army Res Off, Res Triangle Pk, NC 27709 USA. [West, Bruce J.] US Army Res Off, Math & Informat Sci Directorate, ResearchTriangle Pk Research, Res Triangle Pk, NC 27709 USA. RP Grigolini, P (reprint author), Univ N Texas, Ctr Nonlinear Sci, Dept Phys, 1155 Union Circle 311427, Denton, TX 76203 USA. NR 52 TC 0 Z9 0 U1 0 U2 0 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA PAPPELALLEE 3, W-69469 WEINHEIM, GERMANY BN 978-3-527-65103-0; 978-3-527-41104-7 PY 2014 BP 485 EP 507 PG 23 WC Neurosciences SC Neurosciences & Neurology GA BD0UX UT WOS:000357734300023 ER PT B AU West, BJ Turalska, M Grigolini, P AF West, Bruce J. Turalska, Malgorzata Grigolini, Paolo BE Plenz, D Niebur, E TI Complex Networks: From Social Crises to Neuronal Avalanches SO CRITICALITY IN NEURAL SYSTEMS LA English DT Proceedings Paper CT Conference on Criticality in Neural Systems CY APR 30-MAY 01, 2012 CL Natl Inst Hlth, Bethesda, MD HO Natl Inst Hlth ID SCALE-FREE DYNAMICS; SMALL-WORLD; FUNCTIONAL CONNECTIVITY; SYNCHRONIZATION; HYPOTHESIS; BRAIN C1 [West, Bruce J.] US Army, Res Off, ResearchTriangle Pk Research, Math & Informat Sci Directorate, Res Triangle Pk, NC 27709 USA. [Turalska, Malgorzata; Grigolini, Paolo] Univ N Texas, Dept Phys, Ctr Nonlinear Sci, Denton, TX 76203 USA. RP West, BJ (reprint author), US Army, Res Off, ResearchTriangle Pk Research, Math & Informat Sci Directorate, Res Triangle Pk, NC 27709 USA. NR 42 TC 0 Z9 0 U1 0 U2 1 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA PAPPELALLEE 3, W-69469 WEINHEIM, GERMANY BN 978-3-527-65103-0; 978-3-527-41104-7 PY 2014 BP 509 EP 523 PG 15 WC Neurosciences SC Neurosciences & Neurology GA BD0UX UT WOS:000357734300024 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Fundamentals of Risk Management SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 1 EP 15 PG 15 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200002 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Intentional Torts SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 17 EP 30 PG 14 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200003 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Police Liability and Risk Management Torts, Civil Rights, and Employment Law Preface SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Editorial Material; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP XVII EP + PG 4 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200001 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Negligence SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 31 EP 38 PG 8 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200004 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Duty of Care SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 39 EP 58 PG 20 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200005 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Nuisance SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 59 EP 60 PG 2 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200006 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Defamation SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 61 EP 66 PG 6 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200007 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Invasion of Privacy SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 67 EP 76 PG 10 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200008 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Misrepresentation SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 77 EP 80 PG 4 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200009 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Liabilities and Common Claims SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 81 EP 91 PG 11 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200010 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Products Liability SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 93 EP 119 PG 27 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200011 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Strict Liability SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 121 EP 124 PG 4 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200012 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Common Claims Negligent Operation of Emergency Vehicles and Pursuits SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 125 EP 138 PG 14 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200013 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Civil Rights SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 141 EP 187 PG 47 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200014 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Use of Force SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 189 EP 216 PG 28 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200015 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Employment Law SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 219 EP 256 PG 38 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200016 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Labor Law SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 257 EP 258 PG 2 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200017 ER PT B AU Girod, RJ AF Girod, Robert J. BA Girod, RJ BF Girod, RJ TI Risk Management Recapitulation and Retrospective SO POLICE LIABILITY AND RISK MANAGEMENT: TORTS, CIVIL RIGHTS, AND EMPLOYMENT LAW LA English DT Article; Book Chapter C1 [Girod, Robert J.] Haviland Police Dept, Clay City, IN USA. [Girod, Robert J.] Ft Wayne Police Dept, Ft Wayne, IN USA. [Girod, Robert J.] Police Pens Board, New York, NY USA. [Girod, Robert J.] Reg Publ Safety Acad, Ft Wayne Police Acad, Ft Wayne, IN USA. [Girod, Robert J.] US Marshals Serv, Kansas City, KS USA. [Girod, Robert J.] Indianapolis Police Dept, Indianapolis, IN USA. [Girod, Robert J.] Indiana Univ, Police Dept, Bloomington, IN 47405 USA. [Girod, Robert J.] Ohio Bur Criminal Invest, Columbus, OH USA. [Girod, Robert J.] Indiana Dept Insurance, Indianapolis, IN USA. [Girod, Robert J.] Wells Cty Prosecutors Off, Jeffersonville, IN USA. [Girod, Robert J.] Zeis Secur Syst, Gurgaon, Haryana, India. [Girod, Robert J.] Indiana Guard Reserve, Indianapolis, IN USA. [Girod, Robert J.] US Army Reserve, New York, NY USA. [Girod, Robert J.] US Army Criminal Invest Command USACIDC, New York, NY USA. [Girod, Robert J.] Indiana Univ, Bloomington, IN 47405 USA. Boston Univ, Boston, MA 02215 USA. Huntington Univ, Huntington, IN USA. Concordia Univ Wisconsin, Mequon, WI USA. Taylor Univ, Ft Wayne, IN USA. Indiana Wesleyan Univ, Ft Wayne, IN USA. Northcent Univ, Prescott, AZ USA. Union Inst & Univ, Brattleboro, VT USA. Ft Wayne Allen Cty Hist Soc, Hist Ctr, Ft Wayne, IN USA. RP Girod, RJ (reprint author), Robert J Girod Consulting LLC, Ft Wayne, IN 46853 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-9313-8; 978-1-4665-9312-1 PY 2014 BP 261 EP 275 PG 15 WC Criminology & Penology SC Criminology & Penology GA BC8QF UT WOS:000355999200018 ER PT J AU Bell, ZM Teague, LTCE AF Bell, Zachary M. Teague, L. T. C. Edward GP IEEE TI Comparison of Army Aviation Maintenance Methods via Discrete Event Simulation SO 2014 SYSTEMS AND INFORMATION ENGINEERING DESIGN SYMPOSIUM (SIEDS) LA English DT Proceedings Paper CT IEEE Systems and Information Engineering Design Symposium (SIEDS) CY APR 25, 2014 CL Univ Virginia, Charlottesville, VA SP IEEE, IEEE Syst Man & Cybernet Soc HO Univ Virginia AB Army Aviation utilizes two distinct types of overhaul maintenance schedules on its rotary wing aircraft, Phase Maintenance and Progressive Phase Maintenance. All but one aircraft, the OH-58D Kiowa Warrior, use Phase Maintenance. This aircraft has both the highest operational readiness rate and average flight hours in the Army's rotary wing fleet. The Army values uniformity in maintenance procedures across its fleets; however this inconsistency has existed for two decades. This study models the value and tradeoffs of one method versus the other using discrete event simulation. Progressive Phase Maintenance offers more efficiency in terms of time available for missions and may be applicable other airframes. Using the airframe specific Aeronautical Equipment Maintenance Management Policies and Procedures Training Manual and a operational data set from a deployed aviation unit, this study compares the two overhaul maintenance schedules in terms of operational readiness. The effectiveness of each method is measured in the amount of time each airframe is for missions. C1 [Bell, Zachary M.; Teague, L. T. C. Edward] US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA. RP Bell, ZM (reprint author), US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA. EM zachary.bell@usma.edu; edward.teague@usma.edu NR 8 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-4836-9 PY 2014 PG 6 WC Computer Science, Information Systems; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BC9JP UT WOS:000356499600046 ER PT J AU Bennett, J Lee, J Sikorski, M Taylor, D AF Bennett, Jacob Lee, Jordan Sikorski, Michael Taylor, Della GP IEEE TI Intelligence Surveillance Reconnaissance "Search Window" SO 2014 SYSTEMS AND INFORMATION ENGINEERING DESIGN SYMPOSIUM (SIEDS) LA English DT Proceedings Paper CT IEEE Systems and Information Engineering Design Symposium (SIEDS) CY APR 25, 2014 CL Univ Virginia, Charlottesville, VA SP IEEE, IEEE Syst Man & Cybernet Soc HO Univ Virginia AB This report was commissioned by Lockheed Martin Corporation in order to develop a predictive model capable of identifying potential enemy ballistic missile launch sites prior to launch. This model will use geospatial data in conjunction with intelligence, surveillance, and reconnaissance assets in order to identify likely missile launch sites. The utilization of this model will save time when planning missions and engaging targets. This model will provide the commander with the ability destroy a launch site before it has a chance to fire a missile. Since enemy offensive missiles heavily outnumber the amount of American defensive missiles, this model uses an offensive approach in a field that has historically taken a defensive stance. Destroying enemy launch sites before they can fire ensures the most efficient use of missile assets. The prototype algorithm will be built using a commercial geospatial software tool, ArcGIS, and evaluating open-source data. The prototype will evaluate geographical data in order to focus assets on areas that are conducive to missile launch sites. This algorithm will then be exported to a tactical operating system capable of simulating missile engagements on a global scale and allowing commanders to make informed decisions regarding missile threats. The result of this project will have two parts. The first part will be a model in ArcGIS that will identify potential enemy launch sites based on geographic location and characteristics of the terrain. The second part of this project will be a graphical display that will output all relevant information to the commander. This information will include the coordinates of the possible launch sites, expected missile type, and range of each weapon system. C1 [Bennett, Jacob; Lee, Jordan; Sikorski, Michael; Taylor, Della] US Mil Acad, West Point, NY 10996 USA. RP Bennett, J (reprint author), US Mil Acad, West Point, NY 10996 USA. EM jacob.bennett@usma.edu; jordan.lee@usma.edu; michael.sikorski@usma.edu; della.taylor@usma.edu NR 6 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-4836-9 PY 2014 PG 6 WC Computer Science, Information Systems; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BC9JP UT WOS:000356499600017 ER PT J AU D'Antonio, C Gower, S Young, A Teague, E AF D'Antonio, Collin Gower, Stephanie Young, Andrea Teague, Edward GP IEEE TI Non-Kinetic Operations for Stabilizing Government SO 2014 SYSTEMS AND INFORMATION ENGINEERING DESIGN SYMPOSIUM (SIEDS) LA English DT Proceedings Paper CT IEEE Systems and Information Engineering Design Symposium (SIEDS) CY APR 25, 2014 CL Univ Virginia, Charlottesville, VA SP IEEE, IEEE Syst Man & Cybernet Soc HO Univ Virginia DE Counterinsurgency (COIN); non-kinetic operations; PMESII; war games AB The United States Army uses war games to better understand the outcome of military maneuvers before formal executed. These war games seldom include the use of non-kinetic tactics and counterinsurgency doctrine. Thus, they limit viable courses of action that can be taken in support of regional stability. This study uses a regression model to model the integration of non-kinetic actions into a war game and produce a measure of stability for every action that is taken. It will allow military leadership to assess non-kinetic effects using a general model that can be applied to a broad set of regions. C1 [D'Antonio, Collin; Gower, Stephanie; Young, Andrea; Teague, Edward] US Mil Acad, West Point, NY 10996 USA. RP D'Antonio, C (reprint author), US Mil Acad, West Point, NY 10996 USA. EM Collin.D'Antonio@usma.edu; Stephanie.Gower@usma.edu; Andrea.Young@usma.edu; Edward.Teague@usma.edu NR 11 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-4836-9 PY 2014 PG 6 WC Computer Science, Information Systems; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BC9JP UT WOS:000356499600016 ER PT J AU Dewoody, R Hayes, J Isnardi, N Kalinka, J Teague, LTCE AF Dewoody, Robert Hayes, Jacob Isnardi, Nick Kalinka, Joseph Teague, L. T. C. Edward GP IEEE TI Irregular Warfare Models for Regional Stability Development SO 2014 SYSTEMS AND INFORMATION ENGINEERING DESIGN SYMPOSIUM (SIEDS) LA English DT Proceedings Paper CT IEEE Systems and Information Engineering Design Symposium (SIEDS) CY APR 25, 2014 CL Univ Virginia, Charlottesville, VA SP IEEE, IEEE Syst Man & Cybernet Soc HO Univ Virginia AB A war game can be defined as a realistic representation of inputs and outcomes in line with real world situations in a military environment. The Center for Army Analysis runs a war game simulation in order to gain insights and analyze counterinsurgency operations for higher level military commanders. The war gaming process is designed to develop a methodology that allows for the analysis of counterinsurgency operations at the operation/strategic levels. The adjudication table within the war game is used to predict outcomes based on troop levels, and is based solely on data from U.S. counterinsurgency missions in Iraq. With the withdrawal of forces from Iraq and now soon Afghanistan, it will be important to expand the scope of the adjudication table in order to improve the adaptability and accuracy of the war gaming process. An expanded adjudication table will allow the process to model counterinsurgency operations of the future that we have little knowledge of today. It can expedite decision making at the strategic level by modeling a wider expanse of solutions for an unfamiliar war zone. Outcomes can consist of a variety of possibilities to include number of insurgent attacks, total number of insurgents, and troop levels required to defeat the insurgency. In order to expand the scope of the adjudication table we have analyzed a number of counterinsurgency operations across a wide variety of countries and time periods. Incorporating additional conflicts into the adjudication table will allow for the adaptation of the war game to any potential number of conflicts in the future. C1 [Dewoody, Robert; Hayes, Jacob; Isnardi, Nick; Kalinka, Joseph; Teague, L. T. C. Edward] US Mil Acad, West Point, NY 10996 USA. RP Dewoody, R (reprint author), US Mil Acad, West Point, NY 10996 USA. EM robert.dewoody@usma.edu; jacob.hayes@usma.edu; nicholas.isnardi@usma.edu; joseph.kalinka@usma.edu; edward.teague@usma.edu NR 7 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-4836-9 PY 2014 PG 6 WC Computer Science, Information Systems; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BC9JP UT WOS:000356499600034 ER PT J AU Eaton, J Kalnins, R McKearn, M Wilson, P Zecha, A AF Eaton, Joshua Kalnins, Ryan McKearn, Mitchell Wilson, Preston Zecha, Andrew GP IEEE TI Verification and Validation of the Infantry Warrior Simulation (IWARS) through Engagement Effectiveness Modeling and Statistical Analysis SO 2014 SYSTEMS AND INFORMATION ENGINEERING DESIGN SYMPOSIUM (SIEDS) LA English DT Proceedings Paper CT IEEE Systems and Information Engineering Design Symposium (SIEDS) CY APR 25, 2014 CL Univ Virginia, Charlottesville, VA SP IEEE, IEEE Syst Man & Cybernet Soc HO Univ Virginia DE Combat Modeling; Infantry Warrior Simulation; Body Part Hit Distribution; Army Material Systems Analysis Activity; Validation; Verification; Statistical Analysis AB The United States Military uses simulations extensively in order to conduct detailed cost benefit analysis, facilitate the procurement, development and testing of systems, and to train and educate service members. The models that the military uses are only beneficial as long as they accurately mirror reality based on known data. As combat evolves, simulations must improve at a matched rate in order to stay relevant. Currently, the Infantry Warrior Simulation (IWARS) program has been through limited validation processes concerning its data on body hit distributions in the simulation versus the body hit distributions from actual combat. The IWARS models are developed through firsthand accounts collected through extensive research and stakeholder analysis. Common aspects of current engagements are then combined into a number of scenarios that the project team will simulate through IWARS. The project team will then use statistical analysis to compare the real and virtual data sets to determine to what degree the simulation matches the collected historical data. The project team will run multiple scenarios and trials in order to create statistically significant data. At the conclusion of this research project and through detailed statistical analysis, the design team will validate the IWARS output against historical data. C1 [Eaton, Joshua; Kalnins, Ryan; McKearn, Mitchell; Wilson, Preston; Zecha, Andrew] US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA. RP Eaton, J (reprint author), US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA. EM joshua.eaton@usma.edu; ryan.kalnins@usma.edu; mitchell.mckearn@usma.edu; preston.wilson@usma.edu; mndrew.zecha@usma.edu NR 6 TC 0 Z9 0 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-4836-9 PY 2014 PG 6 WC Computer Science, Information Systems; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BC9JP UT WOS:000356499600043 ER PT J AU Egan, J Eo, D Hughes, M Lee, J AF Egan, John Eo, Daniel Hughes, Matthew Lee, Jason GP IEEE TI SAGE Urban Operations Tool Suite Methodology SO 2014 SYSTEMS AND INFORMATION ENGINEERING DESIGN SYMPOSIUM (SIEDS) LA English DT Proceedings Paper CT IEEE Systems and Information Engineering Design Symposium (SIEDS) CY APR 25, 2014 CL Univ Virginia, Charlottesville, VA SP IEEE, IEEE Syst Man & Cybernet Soc HO Univ Virginia AB As the US Army transitions to a regionally aligned architecture, analysts are seeking new and innovative geospatial applications to inform the operations planning process for unfamiliar terrain. In this paper, we outline our systems approach used to develop a suite of geospatial analysis tools used to plan military operations in the urban environment as part of a larger research effort to develop tactical geospatial tools for the US Army (Situational Awareness Geospatially Enabled (SAGE)). This paper describes the iterative stakeholder analysis used to accurately identify operational needs, requirements, capability gaps and associated importance, and the comprehensive methodology used to generate the suite of tools. This research was unique in that we simultaneously developed a recommended suite of tools in addition to a formalized geospatial tool development methodology for the clients' later use. This paper describes the development and application of this methodology which categorically decomposed military operations, aligned stakeholder requirements with existing capabilities, and architected new geospatial capabilities consistent with the existing geospatial program architecture. Key to the developed methodology is that it produced geospatial tools which capitalized upon previously developed technologies, maintained the program's operational theme, and logically developed capabilities which directly satisfied requirements. C1 [Egan, John; Eo, Daniel; Hughes, Matthew; Lee, Jason] US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA. RP Egan, J (reprint author), US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA. EM John.Egan@usma.edu; Daniel.Eo@usma.edu; Matthew.Hughes2@usma.edu; Jason.Lee@usma.edu NR 6 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-4836-9 PY 2014 PG 6 WC Computer Science, Information Systems; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BC9JP UT WOS:000356499600036 ER PT J AU Melville, S Kastl, G Licklider, CAR AF Melville, Sarah Kastl, Garrett Licklider, Christy A. R. GP IEEE TI Systems Thinking Applied to Slavery SO 2014 SYSTEMS AND INFORMATION ENGINEERING DESIGN SYMPOSIUM (SIEDS) LA English DT Proceedings Paper CT IEEE Systems and Information Engineering Design Symposium (SIEDS) CY APR 25, 2014 CL Univ Virginia, Charlottesville, VA SP IEEE, IEEE Syst Man & Cybernet Soc HO Univ Virginia DE Slavery; Soft System Dynamics Methodology; Soft Systems Methodology; System Dynamics AB This study utilizes soft system dynamics methodology to analyze modern-day slavery in order to increase understanding and communicate the complexities of slavery. The authors collaborated with Free The Slaves (FTS), a Washington D.C.-based non-governmental organization, in order to gain feedback throughout the modeling process. FTS activists conduct frontline work and have an expertise in understanding how people become susceptible to slavery, victims of slavery, how they are freed, and how they can become slave-proof or highly unlikely to be susceptible to slavery. The authors are currently creating a base macro model of the variables that affect how a community first becomes susceptible to slavery, which will theoretically represent any community in the world. This model will then be tested using assessment data collected by FTS on the North and South Kivu Regions of the Democratic Republic of the Congo (DRC). This analysis of the DRC may include slavery's roots, geography, growth, magnitude, supply chain of the mining and movement of conflict minerals, the role of law and local organizations, and an overlay of how FTS affects the system. While the ultimate goal for this research is to create proposals for desirable and culturally feasible changes that can reduce the extent of slavery in the North and South Kivu Regions of the DRC, this paper focuses on the first stages of analysis and the base model of the factors that make a community vulnerable to slavery. This paper recommends areas for future research and discussion on how to build further upon the base model. C1 [Melville, Sarah; Kastl, Garrett; Licklider, Christy A. R.] US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA. [Melville, Sarah; Kastl, Garrett] US Mil Acad, Dept Social Sci, West Point, NY 10996 USA. RP Melville, S (reprint author), US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA. EM Sarah.Melville@usma.edu; Garrett.Kastl@usma.edu; Christy.Licklider@usma.edu NR 16 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-4836-9 PY 2014 PG 6 WC Computer Science, Information Systems; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BC9JP UT WOS:000356499600049 ER PT J AU Bertha, C AF Bertha, Carlos GP IEEE TI Ethics and Military Engineering Operations SO 2014 IEEE INTERNATIONAL SYMPOSIUM ON ETHICS IN SCIENCE, TECHNOLOGY AND ENGINEERING LA English DT Proceedings Paper CT IEEE International Symposium on Ethics in Science, Technology and Engineering CY MAY 23-24, 2014 CL Chicago, IL SP IEEE DE engineering ethics; military ethics; military engineering; just war theory AB Imagine the following three-variable Venn diagram: One circle represents the field of applied and professional ethics, a second circle represents military operations, and the third circle represents the practice of engineering, particularly construction projects. We can, without much difficulty, picture what the overlapping areas between any two circles refer to: engineering ethics, military ethics and military engineering. What I would like to address in this paper is the area common to all three circles: is there room for a unique field of ethics called "military engineering ethics"? I contend that there is, and in this presentation I propose to sketch out why and what that might look like. C1 [Bertha, Carlos] US Air Force Acad, Dept Philosophy, Colorado Springs, CO 80840 USA. [Bertha, Carlos] US Army Reserves, Ft Bragg, NC USA. RP Bertha, C (reprint author), US Air Force Acad, Dept Philosophy, Colorado Springs, CO 80840 USA. EM carl.bertha@usafa.edu NR 4 TC 0 Z9 0 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-4992-2 PY 2014 PG 4 WC Computer Science, Interdisciplinary Applications; Ethics; History & Philosophy Of Science SC Computer Science; Social Sciences - Other Topics; History & Philosophy of Science GA BC9DX UT WOS:000356362200007 ER PT S AU Lelis, AJ Green, R El, M Habersat, DB AF Lelis, A. J. Green, R. El, M. Habersat, D. B. BE Shenai, K Dudley, M Bakowski, M Ohtani, N TI Reliability of Commercially Available SiC Power MOSFETs SO GALLIUM NITRIDE AND SILICON CARBIDE POWER TECHNOLOGIES 4 SE ECS Transactions LA English DT Proceedings Paper CT 4th Symposium on Gallium Nitride (GaN) and Silicon Carbide (SiC) Power Technologies CY OCT 05-09, 2014 CL Cancun, MEXICO SP Electron & Photon Div, Dielectr Sci & Technol Div, US Natl Sci Fdn, IEEE Power Elect Soc ID THRESHOLD-VOLTAGE INSTABILITY; HIGH-TEMPERATURE RELIABILITY; STRESS; DEGRADATION; DEPENDENCE; STABILITY; ISSUES AB Results are presented indicating a disparity in the response of different vendors' commercially available SiC power MOSFETs to bias temperature stressing. In addition, it was observed that bias-temperature stress under negative gate bias led to larger shifts in the threshold voltage than under positive gate bias. C1 [Lelis, A. J.; Green, R.; El, M.; Habersat, D. B.] US Army Res Lab, Adelphi, MD 20783 USA. RP Lelis, AJ (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 17 TC 1 Z9 1 U1 2 U2 4 PU ELECTROCHEMICAL SOC INC PI PENNINGTON PA 65 S MAIN ST, PENNINGTON, NJ 08534-2839 USA SN 1938-5862 BN 978-1-60768-544-9 J9 ECS TRANSACTIONS PY 2014 VL 64 IS 7 BP 79 EP 85 DI 10.1149/06407.0079ecst PG 7 WC Electrochemistry; Materials Science, Multidisciplinary; Materials Science, Characterization & Testing SC Electrochemistry; Materials Science GA BC9PM UT WOS:000356771100009 ER PT S AU Lenahan, PM Cochrane, CJ Lelis, AJ AF Lenahan, P. M. Cochrane, C. J. Lelis, A. J. BE Shenai, K Dudley, M Bakowski, M Ohtani, N TI High, Low, and Zero Field Spin Dependent Recombination in 4H SiC Metal Oxide Semiconductor Field Effect and Bipolar Junction Transistors SO GALLIUM NITRIDE AND SILICON CARBIDE POWER TECHNOLOGIES 4 SE ECS Transactions LA English DT Proceedings Paper CT 4th Symposium on Gallium Nitride (GaN) and Silicon Carbide (SiC) Power Technologies CY OCT 05-09, 2014 CL Cancun, MEXICO SP Electron & Photon Div, Dielectr Sci & Technol Div, US Natl Sci Fdn, IEEE Power Elect Soc ID CENTERS; SILICON; RESONANCE; HYDROGEN; PASSAGE AB Silicon carbide based transistors have great promise in high temperature and high power applications. In particular, the great promise of silicon carbide based metal oxide semiconductor field effect transistors (MOSFETs) has been somewhat limited by materials physics problems in the region near the silicon carbide-silicon dioxide interface. Materials physics problems in SiC bipolar junction transistors (BJTs) are also topics of current interest. Studies involving a combination of high, low, and zero field electrically detected magnetic resonance via spin dependent recombination provide a powerful approach for the understanding of SiC transistor materials physics problems. In this paper, we will review our group's work on multi-field spin dependent recombination of 4H SiC based MOSFETs and BJTs. We emphasize the physical principles involved in the measurements in part because they could potentially be quite useful if they were to be applied to other wide band gap semiconductor device systems. C1 [Lenahan, P. M.; Cochrane, C. J.] Penn State Univ, Dept Engn Sci & Mech, University Pk, PA 16802 USA. [Lelis, A. J.] US Army Res Lab, Adelphi, MD 20783 USA. RP Lenahan, PM (reprint author), Penn State Univ, Dept Engn Sci & Mech, 227 Hammond Bldg, University Pk, PA 16802 USA. NR 23 TC 0 Z9 0 U1 2 U2 7 PU ELECTROCHEMICAL SOC INC PI PENNINGTON PA 65 S MAIN ST, PENNINGTON, NJ 08534-2839 USA SN 1938-5862 BN 978-1-60768-544-9 J9 ECS TRANSACTIONS PY 2014 VL 64 IS 7 BP 111 EP 122 DI 10.1149/06407.0111ecst PG 12 WC Electrochemistry; Materials Science, Multidisciplinary; Materials Science, Characterization & Testing SC Electrochemistry; Materials Science GA BC9PM UT WOS:000356771100012 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Hydro-Environmental Analysis Freshwater Environments Introduction SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Editorial Material; Book Chapter C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 7 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 1 EP 12 PG 12 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100002 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Rivers and Streams, Characteristics SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 40 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 15 EP 45 PG 31 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100003 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Hydro-Environmental Analysis Freshwater Environments Preface SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Editorial Material; Book Chapter C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP XVII EP XVIII PG 2 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100001 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Regulated Rivers SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 34 TC 0 Z9 0 U1 1 U2 1 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 47 EP 81 PG 35 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100004 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Flows and Transport in Rivers Measurement and Analysis SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter ID HYDROLOGIC ALTERATION; REQUIREMENTS; STREAMS C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 96 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 83 EP 127 PG 45 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100005 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Selected Water Quality Processes in Rivers and Streams SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter ID HUMAN HEALTH; ANTIBIOTICS; RADIATION C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 60 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 129 EP 161 PG 33 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100006 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Biota of Rivers and Streams An Introduction SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Editorial Material; Book Chapter C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 31 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 163 EP 184 PG 22 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100007 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Measures of the Health of Rivers and Streams SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter ID BIOLOGICAL INTEGRITY; WATER; DIVERSITY; BIODIVERSITY; MANAGEMENT; REGIMES; FISH C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 49 TC 0 Z9 0 U1 1 U2 1 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 185 EP 210 PG 26 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100008 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Introduction to Stream Restoration SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Editorial Material; Book Chapter ID RIVER RESTORATION; DAM REMOVAL; FISH HABITAT; CHANNELS; MEANDERS; DESIGN C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 115 TC 0 Z9 0 U1 0 U2 1 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 211 EP 272 PG 62 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100009 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Introduction to Lakes and Reservoirs Geomorphology and Classification SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Editorial Material; Book Chapter C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 16 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 275 EP 288 PG 14 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100010 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Those Dammed Lakes SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 33 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 289 EP 316 PG 28 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100011 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Zones and Shapes in Lakes and Reservoirs SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 25 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 317 EP 328 PG 12 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100012 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Light and Heat in Lakes and Reservoirs SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 30 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 329 EP 347 PG 19 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100013 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Transport and Mixing Processes in Lakes and Reservoirs SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter ID WATER C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 34 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 349 EP 365 PG 17 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100014 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Chemical and Water Quality Kinetic Characteristics and Processes SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter ID OXYGEN-TRANSFER; SEDIMENTS; TOXICITY; DYNAMICS; MARINE; MODEL; LAKES C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 62 TC 0 Z9 0 U1 0 U2 1 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 367 EP 410 PG 44 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100015 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Biota of Lakes and Reservoirs SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter ID ANAEROBIC AMMONIUM OXIDATION; MUSSEL DREISSENA-POLYMORPHA; LAMPREY PETROMYZON-MARINUS; EUROPEAN LAKES; SAGINAW BAY; HURON; NITROGEN; ERIE; SEA; EUTROPHICATION C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 71 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 411 EP 448 PG 38 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100016 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Lake Production, Succession, and Eutrophication SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter ID WATER; INDEX C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 50 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 449 EP 466 PG 18 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100017 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Restoration and Management of Lakes and Reservoirs SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter ID EURASIAN WATERMILFOIL C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 36 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 467 EP 490 PG 24 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100018 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Dam Tailwaters SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 22 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 491 EP 507 PG 17 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100019 ER PT B AU Martin, JL AF Martin, James Lenial BA Martin, JL BF Martin, JL TI Freshwater Wetlands An Introduction SO HYDRO-ENVIRONMENTAL ANALYSIS: FRESHWATER ENVIRONMENTS LA English DT Article; Book Chapter C1 [Martin, James Lenial] Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. [Martin, James Lenial] US EPA, Large Lakes Res Stn, Grosse Ile, MI USA. [Martin, James Lenial] US Army, Corps Engineers, Waterways Expt Stn, Vicksburg, MS USA. [Martin, James Lenial] ASCI Corp, Engn, Tokyo, Japan. [Martin, James Lenial] Amer Soc Civil Engineers, New York, NY USA. RP Martin, JL (reprint author), Mississippi State Univ, Dept Civil & Environm Engn, Civil Engn, Mississippi State, MS 39762 USA. NR 50 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4822-0608-1; 978-1-4822-0607-4 PY 2014 BP 509 EP 534 PG 26 WC Environmental Sciences; Water Resources SC Environmental Sciences & Ecology; Water Resources GA BC7PT UT WOS:000355140100020 ER PT B AU Allen, N AF Allen, Nate BA McCauley, CD DeRue, DS Yost, PR Taylor, S BF McCauley, CD DeRue, DS Yost, PR Taylor, S TI CompanyCommand: A Peer-to-Peer Learning Forum SO EXPERIENCE-DRIVEN LEADER DEVELOPMENT: MODELS, TOOLS, BEST PRACTICES, AND ADVICE FOR ON-THE-JOB DEVELOPMENT LA English DT Article; Book Chapter C1 [Allen, Nate] Natl Def Univ, US Army, Washington, DC 20319 USA. [Allen, Nate] Natl Def Univ, McNair, DC USA. RP Allen, N (reprint author), Natl Def Univ, US Army, Washington, DC 20319 USA. NR 2 TC 1 Z9 1 U1 0 U2 0 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND BN 978-1-118-76765-8; 978-1-118-45807-5 PY 2014 BP 279 EP 285 D2 10.1002/9781118918838 PG 7 WC Management SC Business & Economics GA BC7IH UT WOS:000354896200049 ER PT S AU Wang, P Henz, B AF Wang, Peng Henz, Brian GP IEEE TI Throughput Analysis of Channel Surfing in Jammed Single-Hop Wireless Networks SO 2014 WIRELESS TELECOMMUNICATIONS SYMPOSIUM (WTS) SE Wireless Telecommunications Symposium LA English DT Proceedings Paper CT 13th Annual Wireless Telecommunications Symposium (WTS) CY APR 09-11, 2014 CL Washington, DC SP IEEE Commun Soc, IEEE Commun & Informat Secur Tech Comm, Cal Poly Pomonas Coll Business Adm, Cal Poly Pomonas Coll Engn, Cal Poly Pomonas Comp Informat Syst Dept, Cal Poly Pomonas Elect & Comp Engn Dept, MESAQIN ID JAMMING ATTACKS AB We develop a theoretical approach to derive system throughput for single-hop wireless networks where U users share a spectrum set theta(U) of n independent channels, and J jammers attack the system by selecting channels from a spectrum set theta(J) of N independent channels while theta(U) subset of theta(J). Users and jammers follow the given policies to randomly select channels at each time slot. The whole system can be modeled as a Markov chain. The key point is to derive the transition probability matrix and obtain the stationary distribution. Then, the theoretical system throughput can be computed straightforwardly. Another interesting problem is to study the system failure probability for the scenario where each user pair has multiple links. The network model is modified as: m user pairs share a spectrum set theta(U) and each user pair has c links. System failure happens when at least one user pair fails all of its links. A two-step approach is developed to compute the system failure probability for the modified model. Numerical experiments are used to validate theoretical results. C1 [Wang, Peng; Henz, Brian] Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Wang, P (reprint author), Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. NR 11 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1934-5070 BN 978-1-4799-1297-1 J9 WIREL TELECOMM SYMP PY 2014 PG 8 WC Computer Science, Hardware & Architecture; Engineering, Electrical & Electronic; Telecommunications SC Computer Science; Engineering; Telecommunications GA BC8WA UT WOS:000356138600010 ER PT S AU Gupta, M Gao, J Yan, XF Cam, H Han, JW AF Gupta, Manish Gao, Jing Yan, Xifeng Cam, Hasan Han, Jiawei GP IEEE TI Top-K Interesting Subgraph Discovery in Information Networks SO 2014 IEEE 30TH INTERNATIONAL CONFERENCE ON DATA ENGINEERING (ICDE) SE IEEE International Conference on Data Engineering LA English DT Proceedings Paper CT IEEE 30th International Conference on Data Engineering (ICDE) CY MAR 31-APR 04, 2014 CL Chicago, IL SP IEEE, Microsoft, Qatar Comp Res Inst, HERE Nokia, Purdue Univ, Cyber Ctr, NW Univ, McCormick Sch Engn, Google ID GRAPHS; ISOMORPHISM; ALGORITHM; DATABASES AB In the real world, various systems can be modeled using heterogeneous networks which consist of entities of different types. Many problems on such networks can be mapped to an underlying critical problem of discovering top-K subgraphs of entities with rare and surprising associations. Answering such subgraph queries efficiently involves two main challenges: (1) computing all matching subgraphs which satisfy the query and (2) ranking such results based on the rarity and the interestingness of the associations among entities in the subgraphs. Previous work on the matching problem can be harnessed for a naive ranking-after-matching solution. However, for large graphs, subgraph queries may have enormous number of matches, and so it is inefficient to compute all matches when only the top-K matches are desired. In this paper, we address the two challenges of matching and ranking in top-K subgraph discovery as follows. First, we introduce two index structures for the network: topology index, and graph maximum metapath weight index, which are both computed offline. Second, we propose novel top-K mechanisms to exploit these indexes for answering interesting subgraph queries online efficiently. Experimental results on several synthetic datasets and the DBLP and Wikipedia datasets containing thousands of entities show the efficiency and the effectiveness of the proposed approach in computing interesting subgraphs. C1 [Gupta, Manish] Microsoft, Bangalore, Karnataka, India. [Gao, Jing] SUNY Buffalo, Buffalo, NY 14260 USA. [Yan, Xifeng] Univ Calif Santa Barbara, Santa Barbara, CA 93106 USA. [Cam, Hasan] US Army Res Lab, Adelphi, MD USA. [Han, Jiawei] Univ Illinois, Champaign, IL USA. RP Gupta, M (reprint author), Microsoft, Bangalore, Karnataka, India. EM gmanish@microsoft.com; jing@buffalo.edu; xyan@cs.ucsb.edu; hasan.cam.civ@mail.mil; hanj@cs.uiuc.edu NR 32 TC 6 Z9 8 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1084-4627 BN 978-1-4799-3480-5 J9 PROC INT CONF DATA PY 2014 BP 820 EP 831 PG 12 WC Computer Science, Information Systems SC Computer Science GA BC7YT UT WOS:000355411500070 ER PT J AU Baideme, MP Robbins, CA Starke, JA AF Baideme, Matthew P. Robbins, Cristian A. Starke, Jeffrey A. BE Kongar, E TI A Model to Build, Assess, and Reflect on Students' Metacognition through the Classroom Debate of Controversial Environmental Issues SO 2014 ZONE 1 CONFERENCE OF THE AMERICAN SOCIETY FOR ENGINEERING EDUCATION (ASEE ZONE 1) LA English DT Proceedings Paper CT Zone 1 Conference of the American-Society-for-Engineering-Education (ASEE Zone) CY APR 03-05, 2014 CL Univ Bridgeport, Bridgeport, CT SP American Soc Engn Educ, e Richards Consulting, Sacred Heart Univ, John F Welch Coll Business, Xerox Fdn, Univ Bridgeport, Sch Engn, Decisyon Inc HO Univ Bridgeport DE environmental engineering and environmental science; metacognition assessment; debate assessment techniques; multifaceted controversial environmental issues AB Debates have been used as a tool to promote active learning in the classroom. Role-play debates have been used to bring more realism to the issue being debated. In a junior-level environmental science course, role-play debates were utilized to present and discuss controversial environmental issues in realistic scenarios that occur throughout the United States. Using these debates as a platform, a model to build, assess, and reflect on students' metacognition was developed and implemented. This model provides a method to assess a student's metacognitive ability and allow for reflection and improvement in this area. C1 [Baideme, Matthew P.; Robbins, Cristian A.; Starke, Jeffrey A.] US Mil Acad, Dept Geog & Environm Engn, West Point, NY 10996 USA. RP Baideme, MP (reprint author), US Mil Acad, Dept Geog & Environm Engn, 745 Brewerton Rd, West Point, NY 10996 USA. EM matthew.baideme@usma.edu; cristian.robbins@usma.edu; jeffrey.starke@usma.edu NR 12 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-5233-5 PY 2014 PG 10 WC Education, Scientific Disciplines SC Education & Educational Research GA BC8GM UT WOS:000355666600051 ER PT B AU Rafuse, ES AF Rafuse, Ethan S. BE Rafuse, ES TI CORPS COMMANDERS IN BLUE Union Major Generals in the Civil War Introduction SO CORPS COMMANDERS IN BLUE: UNION MAJOR GENERALS IN THE CIVIL WAR SE Conflicting Worlds-New Dimensions of the American Civil War LA English DT Editorial Material; Book Chapter C1 [Rafuse, Ethan S.] US Mil Acad, Civil War & Mil Hist, West Point, NY USA. [Rafuse, Ethan S.] US Army Command & Gen Staff Coll, Hist, Ft Leavenworth, KS 66027 USA. RP Rafuse, ES (reprint author), US Army Command & Gen Staff Coll, Hist, Ft Leavenworth, KS 66027 USA. NR 27 TC 1 Z9 1 U1 0 U2 0 PU LOUISIANA STATE UNIV PRESS PI BATON ROUGE PA BATON ROUGE, LA 70803 USA BN 978-0-8071-5703-9; 978-0-8071-5702-2 J9 CONFL WOR PY 2014 BP 1 EP 13 PG 13 WC History SC History GA BC6ER UT WOS:000353835600001 ER PT B AU Snell, MA AF Snell, Mark A. BE Rafuse, ES TI William B. Franklin and the XIX Corps in the Trans-Mississippi, 1863-64 SO CORPS COMMANDERS IN BLUE: UNION MAJOR GENERALS IN THE CIVIL WAR SE Conflicting Worlds-New Dimensions of the American Civil War LA English DT Article; Book Chapter C1 [Snell, Mark A.] US Mil Acad, Hist, West Point, NY USA. [Snell, Mark A.] Shepherd Univ, George Tyler Moore Ctr Study Civil War, Shepherdstown, WV 25443 USA. [Snell, Mark A.] Shepherd Univ, Hist, Shepherdstown, WV 25443 USA. RP Snell, MA (reprint author), Shepherd Univ, George Tyler Moore Ctr Study Civil War, Shepherdstown, WV 25443 USA. NR 19 TC 0 Z9 0 U1 0 U2 0 PU LOUISIANA STATE UNIV PRESS PI BATON ROUGE PA BATON ROUGE, LA 70803 USA BN 978-0-8071-5703-9; 978-0-8071-5702-2 J9 CONFL WOR PY 2014 BP 181 EP 220 PG 40 WC History SC History GA BC6ER UT WOS:000353835600007 ER PT B AU Rafuse, ES AF Rafuse, Ethan S. BE Rafuse, ES TI "Always 'Fighting Joe'" Joseph Hooker and the Campaign in North Georgia, May-July 1864 SO CORPS COMMANDERS IN BLUE: UNION MAJOR GENERALS IN THE CIVIL WAR SE Conflicting Worlds-New Dimensions of the American Civil War LA English DT Article; Book Chapter C1 [Rafuse, Ethan S.] US Mil Acad, Civil War & Mil Hist, West Point, NY USA. [Rafuse, Ethan S.] US Army Command & Gen Staff Coll, Hist, Ft Leavenworth, KS 66027 USA. RP Rafuse, ES (reprint author), US Army Command & Gen Staff Coll, Hist, Ft Leavenworth, KS 66027 USA. NR 46 TC 0 Z9 0 U1 0 U2 0 PU LOUISIANA STATE UNIV PRESS PI BATON ROUGE PA BATON ROUGE, LA 70803 USA BN 978-0-8071-5703-9; 978-0-8071-5702-2 J9 CONFL WOR PY 2014 BP 221 EP 260 PG 40 WC History SC History GA BC6ER UT WOS:000353835600008 ER PT B AU Dissanayake, STM Onal, H Westervelt, JD Balbach, HE AF Dissanayake, Sahan T. M. Oenal, Hayri Westervelt, James D. Balbach, Harold E. BE Nunes, PALD Kumar, P Dedeurwaerdere, T TI Optimal selection of clustered conservation lands using integer programming: the case of Fort Stewart in Georgia, USA SO HANDBOOK ON THE ECONOMICS OF ECOSYSTEM SERVICES AND BIODIVERSITY LA English DT Article; Book Chapter ID RESERVE SITE SELECTION; MINIMAL FRAGMENTATION; DESIGN MODELS; NETWORK; CONNECTIVITY; ALGORITHMS; REQUIREMENTS; EXAMPLE; AREA C1 [Dissanayake, Sahan T. M.] Colby Coll, Econ, Waterville, ME 04901 USA. [Dissanayake, Sahan T. M.] Portland State Univ, Portland, OR 97207 USA. [Oenal, Hayri] Univ Illinois, Dept Agr & Consumer Econ, Operat Res, Chicago, IL 60680 USA. [Balbach, Harold E.] US Army Engn Res & Dev Ctr, Champaign, IL USA. RP Dissanayake, STM (reprint author), Colby Coll, Econ, Waterville, ME 04901 USA. OI Dissanayake, Sahan/0000-0002-4342-5979 NR 34 TC 1 Z9 1 U1 0 U2 0 PU EDWARD ELGAR PUBLISHING LTD PI CHELTENHAM PA GLENSANDA HOUSE, MONTPELLIER PARADE, CHELTENHAM GL50 1UA, GLOS, ENGLAND BN 978-1-78195-151-4; 978-1-78195-150-7 PY 2014 BP 193 EP 207 D2 10.4337/9781781951514 PG 15 WC Economics; Environmental Studies SC Business & Economics; Environmental Sciences & Ecology GA BC5GW UT WOS:000353272400012 ER PT J AU Chen, G Liao, LC Li, ZN Drost, RJ Sadler, BM AF Chen, Gang Liao, Linchao Li, Zening Drost, Robert J. Sadler, Brian M. GP IEEE TI Experimental and Simulated Evaluation of Long Distance NLOS UV Communication SO 2014 9TH INTERNATIONAL SYMPOSIUM ON COMMUNICATION SYSTEMS, NETWORKS & DIGITAL SIGNAL PROCESSING (CSNDSP) LA English DT Proceedings Paper CT 9th International Symposium on Communication Systems, Networks & Digital Signal Processing (CSNDSP) CY JUL 23-25, 2014 CL Manchester, ENGLAND DE Ultraviolet communication; non-line-of-sight; long distance; scattering; scintillation ID SIGHT ULTRAVIOLET COMMUNICATIONS; ATMOSPHERIC-TURBULENCE; CHANNELS; SCATTERING; NETWORKS; CONNECTIVITY; PROPAGATION; PERFORMANCE; LINKS; MODEL AB In this paper, experimental measurements of path loss and pulse broadening in long-distance non-line-of-sight (NLOS) ultraviolet (UV) communications are reported and analyzed, with measurements at distances up to 4 km. The comparison of these results with a multiple-scattering channel model based on the Monte Carlo simulation of photon propagation provides strong evidence of the validity of this modeling approach. Additionally, channel models incorporating the effects of turbulence are also considered, but mismatch between experimental results and predictions of the turbulence models suggest the potential for model refinement. Overall, the experimental and simulation results presented here serve to advance the study of NLOS UV channel modeling, an essential component of communication system design. C1 [Chen, Gang; Liao, Linchao; Li, Zening] Univ Calif Riverside, Dept Elect Engn, Riverside, CA 92521 USA. [Drost, Robert J.; Sadler, Brian M.] Army Res Lab, Adelphi, MD 20783 USA. RP Chen, G (reprint author), Univ Calif Riverside, Dept Elect Engn, Riverside, CA 92521 USA. EM gachen@ee.ucr.edu NR 25 TC 3 Z9 3 U1 1 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-2581-0 PY 2014 BP 904 EP 909 PG 6 WC Computer Science, Hardware & Architecture; Engineering, Electrical & Electronic; Telecommunications SC Computer Science; Engineering; Telecommunications GA BC7KD UT WOS:000354963600171 ER PT B AU Jiang, RZ Chu, D AF Jiang, Rongzhong Chu, Deryn BE Chen, Z Dodelet, JP Zhang, J TI Electrocatalysts for Alkaline Polymer Exchange Membrane (PEM) Fuel Cells - Overview SO NON-NOBLE METAL FUEL CELL CATALYSTS LA English DT Article; Book Chapter ID OXYGEN REDUCTION REACTION; HYDROGEN OXIDATION REACTION; RUTHENIUM ANODE CATALYST; PT-AG ELECTRODES; HIGH-AREA CARBON; ETHANOL OXIDATION; SILVER NANOPARTICLES; SODIUM-BOROHYDRIDE; TETRAMETHOXYPHENYL PORPHYRIN; ELECTROCHEMICAL PROPERTIES C1 [Jiang, Rongzhong; Chu, Deryn] US Army Res Lab, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA. RP Jiang, RZ (reprint author), US Army Res Lab, Sensors & Electron Devices Directorate, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 169 TC 1 Z9 1 U1 4 U2 9 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA PAPPELALLEE 3, W-69469 WEINHEIM, GERMANY BN 978-3-527-66490-0; 978-3-527-33324-0 PY 2014 BP 271 EP 317 D2 10.1002/9783527664900 PG 47 WC Energy & Fuels; Engineering, Chemical SC Energy & Fuels; Engineering GA BC5BY UT WOS:000353158000009 ER PT B AU Sano, T Okeke, U Yu, J Boehlert, C Yen, CF AF Sano, Tomoko Okeke, Uchechi Yu, Jian Boehlert, Carl Yen, Chian-Fong GP TMS TI ANALYSIS OF THE MICROSTRUCTURE AND PROPERTIES OF FRICTION STIR WELD ZONES IN THE Al 2139-T8 ALLOY SO TMS 2014 SUPPLEMENTAL PROCEEDINGS LA English DT Proceedings Paper CT 143rd TMS Annual Meeting & Exhibition CY FEB 16-20, 2014 CL San Diego, CA DE Al 2139; Friction Stir Weld; In-Situ Characterization ID ALUMINUM AB The welding process introduces heat, plastic deformation, and chemical variation into the weld joints and modifies the microstructure, strength, and ductility of the welded region. Samples from two plates of Al 2139-T8 alloys welded together by friction stir welding (FSW) were examined. The microstructure of the stir zone (SZ), thermomechanical affected zone (TMAZ), and the unaffected base alloy were evaluated by scanning electron microscopy (SEM) and electron backscattered diffraction. The deformation and quasi-static tensile behavior of the samples from the SZ, TMAZ, and unaffected base alloy were examined by in-situ tensile experiments in the SEM, at room temperature and at 300 degrees C. The SZ samples showed higher elongation to failure and the unaffected base alloy exhibited the least amount of elongation. The ultimate tensile strength was determined to be lower in the TMAZ, and the yield strength increased away from the FSW region. The higher temperature tensile experiments showed a significant reduction in strength. The full results of the effect of the FSW on the Al2139-T8 microstructure and tensile behavior will be discussed in detail. C1 [Sano, Tomoko; Yu, Jian; Yen, Chian-Fong] US Army, Res Lab, RDRL WMM B, Aberdeen Proving Ground, MD 21005 USA. [Okeke, Uchechi; Boehlert, Carl] Michigan State Univ, E Lansing, MI 48824 USA. RP Sano, T (reprint author), US Army, Res Lab, RDRL WMM B, Aberdeen Proving Ground, MD 21005 USA. NR 13 TC 0 Z9 0 U1 0 U2 1 PU JOHN WILEY & SONS INC PI HOBOKEN PA 111 RIVER ST, HOBOKEN, NJ 07030 USA BN 978-1-118-88985-5; 978-1-118-88972-5 PY 2014 BP 547 EP 555 PG 9 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Science & Technology - Other Topics; Materials Science GA BC7JK UT WOS:000354941300066 ER PT B AU Jow, TR Allen, JL Borodin, OA Delp, SA Allen, JL AF Jow, T. Richard Allen, Jan L. Borodin, Oleg A. Delp, Samuel A. Allen, Joshua L. GP TMS TI CHALLENGES IN DEVELOPING HIGH ENERGY DENSITY Li-ION BATTERIES WITH HIGH VOLTAGE CATHODES SO TMS 2014 SUPPLEMENTAL PROCEEDINGS LA English DT Proceedings Paper CT 143rd TMS Annual Meeting & Exhibition CY FEB 16-20, 2014 CL San Diego, CA DE Lithium nickel manganese spinel; lithium cobalt phosphate; lithium-ion batteries; additives; substituted lithium cobalt phosphate ID ELECTROLYTES; TEMPERATURE; INTERFACE; STABILITY; SULFONE; LICOPO4; FE AB The issues of low coulombic efficiency and capacity fading encountered in the development of high voltage spinel LiMn1.5Ni0.5O4 (LNMO) and lithium cobalt phosphate LiCoPO4 (LCP) were reviewed. The developments in the area of electrolytes including the use of additives and fluorinated solvents for improved electrolyte stability and the area of LNMO and LCP cathodes themselves using substitution for stabilizing the cathodes were also reviewed. The advancement of high voltage Li-ion batteries will need to couple the improvement of high voltage cathode materials and electrolytes together for optimum performance. C1 [Jow, T. Richard; Allen, Jan L.; Borodin, Oleg A.; Delp, Samuel A.; Allen, Joshua L.] US Army Res Lab, Adelphi, MD 20783 USA. RP Jow, TR (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. RI Borodin, Oleg/B-6855-2012 OI Borodin, Oleg/0000-0002-9428-5291 NR 14 TC 0 Z9 0 U1 7 U2 12 PU JOHN WILEY & SONS INC PI HOBOKEN PA 111 RIVER ST, HOBOKEN, NJ 07030 USA BN 978-1-118-88985-5; 978-1-118-88972-5 PY 2014 BP 853 EP 857 PG 5 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Science & Technology - Other Topics; Materials Science GA BC7JK UT WOS:000354941300100 ER PT B AU Zhang, SS AF Zhang, Sheng S. GP TMS TI HOW TO USE NANOSTRUCTURED MATERIALS EFFECTIVELY IN RECHARGEABLE LITHIUM/SULFUR BATTERY SO TMS 2014 SUPPLEMENTAL PROCEEDINGS LA English DT Proceedings Paper CT 143rd TMS Annual Meeting & Exhibition CY FEB 16-20, 2014 CL San Diego, CA DE Lithium/sulfur battery; Sulfur-carbon composite; Sulfurized polyacrylonitrile; Solid state electrolyte; Lithium protection; Cycling performance ID SULFUR BATTERIES; CATHODE MATERIAL; COMPOSITE AB Lithium/sulfur (Li/S) battery cannot come into practical applications because of many problems, such as low charging efficiency, high self-discharge rate and short cycle life, all of which are related to the dissolution of high-order lithium polysulfide ( PS, Li2Sn, n >= 4) into the liquid electrolyte and resulting parasitic reactions with the Li anode. Since the dissolution of high-order PS in the liquid electrolyte is inevitable and essential to the cell's performance, one should allow the PS to dissolve while minimizing the parasitic reactions. To do this, nanostructured materials have been widely employed to confine the diffusion of the dissolved PS out of the cathode, such as approaches using highly porous carbon, metal oxide additive, and conductive polymer. In this presentation, we start with the fundamental chemistry of the Li/S battery to review how nanostructured materials can be effectively used in the rechargeable Li/S batteries. C1 US Army, RDRL SED C, Res Lab, Electrochem Branch Sensors & Elect Devices Direct, Adelphi, MD 20783 USA. RP Zhang, SS (reprint author), US Army, RDRL SED C, Res Lab, Electrochem Branch Sensors & Elect Devices Direct, Adelphi, MD 20783 USA. NR 14 TC 0 Z9 0 U1 1 U2 8 PU JOHN WILEY & SONS INC PI HOBOKEN PA 111 RIVER ST, HOBOKEN, NJ 07030 USA BN 978-1-118-88985-5; 978-1-118-88972-5 PY 2014 BP 867 EP 874 PG 8 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Science & Technology - Other Topics; Materials Science GA BC7JK UT WOS:000354941300102 ER PT B AU Rajagopalan, M Bhatia, MA Solanki, KN Tschopp, MA AF Rajagopalan, M. Bhatia, M. A. Solanki, K. N. Tschopp, M. A. GP TMS TI INVESTIGATION OF ATOMIC-SCALE ENERGETICS ON LIQUID METAL EMBRITTLEMENT OF ALUMINUM DUE TO GALLIUM SO TMS 2014 SUPPLEMENTAL PROCEEDINGS LA English DT Proceedings Paper CT 143rd TMS Annual Meeting & Exhibition CY FEB 16-20, 2014 CL San Diego, CA DE Grain Boundary; Segregation; Liquid Metal Embrittlement ID SYMMETRICAL TILT BOUNDARIES; GRAIN-BOUNDARIES; MOLECULAR-DYNAMICS; FCC METALS; ENERGY; PENETRATION; COPPER; GA AB In this work, the role of atomistic-scale energetics on liquid-metal embrittlement of aluminum (Al) due to gallium (Ga) was explored. Ab-initio and molecular mechanics were employed to probe the formation energies of vacancies and segregation energies of Ga for < 100 >, < 110 > and < 111 > symmetric tilt grain boundaries (STGBs) in Al. Results show that site-to-site variation of formation and segregation energies within the boundary are substantial, with the majority of sites having lower energies than the bulk values. Moreover, a few GBs such as Sigma 3(111) and Sigma 11(113) of different tilt axes with relatively high segregation energies (between 0 and -0.1 eV) at the boundary were also found, providing a new atomistic perspective in the GB engineering of material with smart GB networks to mitigate or control LME and more general embrittlement phenomena in alloys. C1 [Rajagopalan, M.; Bhatia, M. A.; Solanki, K. N.] Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85281 USA. [Tschopp, M. A.] Army Res Lab, Weap & Mat Res Directorate, Lightweight & Specialty Met Branch, Aberdeen Proving Ground, MD 21005 USA. RP Rajagopalan, M (reprint author), Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85281 USA. OI Tschopp, Mark/0000-0001-8471-5035 NR 34 TC 0 Z9 0 U1 1 U2 1 PU JOHN WILEY & SONS INC PI HOBOKEN PA 111 RIVER ST, HOBOKEN, NJ 07030 USA BN 978-1-118-88985-5; 978-1-118-88972-5 PY 2014 BP 1069 EP 1076 PG 8 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Science & Technology - Other Topics; Materials Science GA BC7JK UT WOS:000354941300127 ER PT S AU Saponaro, P Sherbondy, K Kambhamettu, C AF Saponaro, Philip Sherbondy, Kelly Kambhamettu, Chandra BE Bebis, G Boyle, R Parvin, B Koracin, D McMahan, R Jerald, J Zhang, H Drucker, SM Kambhamettu, C ElChoubassi, M Deng, Z Carlson, M TI Concealed Target Detection with Fusion of Visible and Infrared SO ADVANCES IN VISUAL COMPUTING (ISVC 2014), PT II SE Lecture Notes in Computer Science LA English DT Proceedings Paper CT 10th International Symposium on Visual Computing (ISVC) CY DEC 08-10, 2014 CL Las Vegas, NV SP UNR Comp Vis Lab, Desert Res Inst, LBNL, NASA Ames, BAE Syst, Intel, Ford, Hewlett Packard, Mitsubishi Elect Res Labs, Toyota, Gen Elect, Berkeley Lab ID LANDMINE DETECTION AB Concealed or buried improvised explosive devices (IEDs) are a major cause of fatalities for both civilians and soldiers. For detecting hidden targets, many technologies have been considered such as ground penetrating radar (GPR), infrared cameras, and even visible wavelength cameras. In this work, we propose fusing visible and infrared sensors for automatic detection of shallowly buried (< 10cm) or above ground targets. We use Gaussian Mixture Models (GMMs) to create a base model of the temperature and color variation of the background scene and dynamically update our models for new scenes. Anomalous temperatures and colors are identified using the GMM components. Fusion is performed at the pixel level, confidence map level, and decision level for comparison. Data was collected with a Xenics Gobi 480 long wave infrared camera and a Canon Powershot A1200 visible wavelength camera with metal targets placed in various concealed configurations. The observed results show that infrared can detect shallowly buried targets and targets above ground "out in the open" effectively, but cannot detect metal targets nearby bushes. Visible cameras, on the other hand, can detect the metal targets in the bushes effectively. Confidence map and decision level fusion led to the best results when there was a mix of buried targets and targets hidden in bushes. C1 [Saponaro, Philip; Kambhamettu, Chandra] Univ Delaware, Dept Comp & Informat Sci, Video Image Modeling & Synth Lab, Newark, DE 19716 USA. [Sherbondy, Kelly] US Army Res Lab, Adelphi, MD 20783 USA. RP Saponaro, P (reprint author), Univ Delaware, Dept Comp & Informat Sci, Video Image Modeling & Synth Lab, Newark, DE 19716 USA. OI Sherbondy, Kelly/0000-0003-4730-3706 NR 16 TC 1 Z9 1 U1 0 U2 1 PU SPRINGER-VERLAG BERLIN PI BERLIN PA HEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY SN 0302-9743 BN 978-3-319-14364-4; 978-3-319-14363-7 J9 LECT NOTES COMPUT SC PY 2014 VL 8888 BP 568 EP 577 PG 10 WC Computer Science, Artificial Intelligence; Computer Science, Theory & Methods; Imaging Science & Photographic Technology SC Computer Science; Imaging Science & Photographic Technology GA BC6ZX UT WOS:000354700300055 ER PT J AU Lange, JMA Ananworanich, J AF Lange, Joep M. A. Ananworanich, Jintanat TI The discovery and development of antiretroviral agents SO ANTIVIRAL THERAPY LA English DT Review ID PLACEBO-CONTROLLED TRIAL; PNEUMOCYSTIS-CARINII-PNEUMONIA; HIV-INFECTED PATIENTS; AIDS-RELATED-COMPLEX; EFAVIRENZ/EMTRICITABINE/TENOFOVIR DISOPROXIL FUMARATE; EXPERIENCED HIV-1-INFECTED PATIENTS; ACQUIRED-IMMUNODEFICIENCY-SYNDROME; ZIDOVUDINE COMBINATION THERAPY; PREVIOUSLY TREATED PATIENTS; T-LYMPHOTROPIC RETROVIRUS AB Since the discovery of HIV as the causative agent of AIDS in 1983/1984, remarkable progress has been made in finding antiretroviral drugs (ARVs) that are effective against it. A major breakthrough occurred in 1996 when it was found that triple drug therapy (HAART) could durably suppress viral replication to minimal levels. It was then widely felt, however, that HAART was too expensive and complex for low-and middle-income countries, and so, with the exception of a few of these countries, such as Brazil, a massive scale-up did not begin until the WHO launched its '3 by 5' initiative and sizeable funding mechanisms, such as the Global Fund to Fight AIDS, TB and Malaria and the US President's Emergency Plan for AIDS Relief (PEPFAR), came into existence. A pivotal enabler of the scale-up was a steady lowering of drug prices through entry of generic antiretrovirals, competition between generic manufacturers and the making of volume commitments. The WHO Prequalification of Medicines Programme and the Expedited Review Provision of the US Food and Drug Administration have been important for the assurance of quality standards. Antiretroviral drug development by research-based pharmaceutical companies continues, with several important innovative products, such as long-acting agents, in the pipeline. C1 [Lange, Joep M. A.] Univ Amsterdam, Acad Med Ctr, Dept Global Hlth, Amsterdam Inst Global Hlth & Dev, NL-1105 AZ Amsterdam, Netherlands. [Ananworanich, Jintanat] Thai Red Cross AIDS Res Ctr, Bangkok, Thailand. [Ananworanich, Jintanat] Walter Reed Army Inst Res, US Mil HIV Res Program, Silver Spring, MD USA. [Ananworanich, Jintanat] Henry M Jackson Fdn Adv Mil Med, Bethesda, MD USA. RP Ananworanich, J (reprint author), Thai Red Cross AIDS Res Ctr, Bangkok, Thailand. EM jananworanich@hivresearch.org NR 127 TC 7 Z9 8 U1 2 U2 5 PU INT MEDICAL PRESS LTD PI LONDON PA 2-4 IDOL LANE, LONDON EC3R 5DD, ENGLAND SN 1359-6535 J9 ANTIVIR THER JI Antivir. Ther. PY 2014 VL 19 SU 3 BP 5 EP 14 DI 10.3851/IMP2896 PG 10 WC Infectious Diseases; Pharmacology & Pharmacy; Virology SC Infectious Diseases; Pharmacology & Pharmacy; Virology GA CI2TZ UT WOS:000354601400003 PM 25310317 ER PT S AU Mayo, M Abdelzaher, A Ghosh, P AF Mayo, Michael Abdelzaher, Ahmed Ghosh, Preetam BE Zhang, Z Wu, L Xu, W Du, DZ TI Mixed Degree-Degree Correlations in Directed Social Networks SO COMBINATORIAL OPTIMIZATION AND APPLICATIONS (COCOA 2014) SE Lecture Notes in Computer Science LA English DT Proceedings Paper CT 8th Annual International Conference on Combinatorial Optimization and Applications (COCOA) CY DEC 19-21, 2014 CL HI ID COMPLEX NETWORKS; DYNAMICS; WEB AB Many complex networks exhibit homophilic, or assortative degree mixing-the tendency for networked nodes to connect with others of similar degree. For social networks, this phenomenon is often referred to colloquially by the mantra 'your friends have more friends than you do.' We analyzed datasets for 16 directed social networks, and report that some of them exhibit both assortative (positive correlations) and disassortative (negative correlations) degree mixing across the totality of their degrees. We show that this mixed trend can be predicted based on the value of Pearson correlations computed for the directed networks. This stands in contrast to previous results reported for social networks that mark them as purely assortative. Finally, we discuss mechanisms by which these trends emerge from random models of network creation. C1 [Mayo, Michael] US Army Engineer Res & Dev Ctr, Environm Lab, Vicksburg, MS 39180 USA. [Abdelzaher, Ahmed; Ghosh, Preetam] Virginia Commonwealth Univ, Dept Comp Sci, Richmond, VA USA. RP Mayo, M (reprint author), US Army Engineer Res & Dev Ctr, Environm Lab, Vicksburg, MS 39180 USA. EM michael.l.mayo@usace.army.mil NR 46 TC 0 Z9 0 U1 0 U2 1 PU SPRINGER-VERLAG BERLIN PI BERLIN PA HEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY SN 0302-9743 BN 978-3-319-12691-3; 978-3-319-12690-6 J9 LECT NOTES COMPUT SC PY 2014 VL 8881 BP 571 EP 580 DI 10.1007/978-3-319-12691-3_42 PG 10 WC Computer Science, Hardware & Architecture; Computer Science, Theory & Methods; Mathematics SC Computer Science; Mathematics GA BC7GO UT WOS:000354861400042 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Concrete Pavement Design, Construction, and Performance Second Edition Introduction SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Editorial Material; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 1 EP + D2 10.1201/b17043 PG 32 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900001 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Types of concrete pavements SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 19 EP 38 D2 10.1201/b17043 PG 20 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900002 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Sustainability of concrete pavements SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 39 EP 51 D2 10.1201/b17043 PG 13 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900003 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Performance SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 53 EP 73 D2 10.1201/b17043 PG 21 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900004 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Subgrades, subbases, and drainage SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 75 EP 92 D2 10.1201/b17043 PG 18 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900005 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Selection of concrete materials SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 93 EP 106 D2 10.1201/b17043 PG 14 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900006 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Mixture design and proportioning SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 107 EP 122 D2 10.1201/b17043 PG 16 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900007 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Design fundamentals SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 123 EP 145 D2 10.1201/b17043 PG 23 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900008 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Highway pavement design SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 147 EP 161 D2 10.1201/b17043 PG 15 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900009 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Mechanistic-Empirical Pavement Design Guide SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 163 EP 184 D2 10.1201/b17043 PG 22 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900010 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Light-duty pavement design SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 185 EP 205 D2 10.1201/b17043 PG 21 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900011 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Pervious concrete pavements SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 207 EP 235 D2 10.1201/b17043 PG 29 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900012 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Airport pavement design SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 237 EP 247 D2 10.1201/b17043 PG 11 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900013 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Industrial pavement design SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 249 EP 258 D2 10.1201/b17043 PG 10 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900014 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Roller-compacted concrete pavements SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 1 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 259 EP 273 D2 10.1201/b17043 PG 15 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900015 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Transitions and CRCP reinforcement SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 275 EP 294 D2 10.1201/b17043 PG 20 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900016 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Subgrade and subbase construction SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 295 EP 306 D2 10.1201/b17043 PG 12 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900017 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Paving SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 307 EP 321 D2 10.1201/b17043 PG 15 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900018 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Finishing, texturing, curing, and joint sawing and sealing SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 323 EP 345 D2 10.1201/b17043 PG 23 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900019 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Concrete pavement maintenance SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 347 EP 353 D2 10.1201/b17043 PG 7 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900020 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Rehabilitation SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 355 EP 368 D2 10.1201/b17043 PG 14 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900021 ER PT B AU Delatte, NJ AF Delatte, Norbert J. BA Delatte, NJ BF Delatte, NJ TI Overlays and inlays SO CONCRETE PAVEMENT: DESIGN, CONSTRUCTION, AND PERFORMANCE, 2ND EDITION LA English DT Article; Book Chapter C1 [Delatte, Norbert J.] Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. [Delatte, Norbert J.] Us Army, Corps Engineers, Ft Knox, KY USA. [Delatte, Norbert J.] US Mil Acad, West Point, NY 10996 USA. [Delatte, Norbert J.] Execut Comm, ASCE Tech Council Forens Engn TCFE, Cleveland, OH USA. RP Delatte, NJ (reprint author), Cleveland State Univ, Dept Civil & Environm Engn, Cleveland, OH 44115 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-4665-7511-0; 978-1-4665-7510-3 PY 2014 BP 369 EP 388 D2 10.1201/b17043 PG 20 WC Construction & Building Technology; Materials Science, Multidisciplinary SC Construction & Building Technology; Materials Science GA BC3ZH UT WOS:000352106900022 ER PT B AU Mogren, ET AF Mogren, Eric T. (Rick) BE Morgan, DF Cook, BJ TI AGENCY IN NETWORKS Implications for Theory and Practice in the New Public Governance SO NEW PUBLIC GOVERNANCE: A REGIME-CENTERED PERSPECTIVE LA English DT Proceedings Paper CT Symposium on Public Service Leadership in a Globalized World CY SEP 30, 2011 CL Portland State Univ, Portland, OR SP Hatfield Sch Govt Ctr Public Serv HO Portland State Univ C1 [Mogren, Eric T. (Rick)] Portland State Univ, Ctr Publ Serv, Hatfield Sch Govt, Portland, OR 97207 USA. [Mogren, Eric T. (Rick)] Portland State Univ, Ctr Publ Serv, Hatfield Sch Govt, Publ Adm, Portland, OR 97207 USA. [Mogren, Eric T. (Rick)] US Army Corps Engineers, Washington, DC USA. RP Mogren, ET (reprint author), Portland State Univ, Ctr Publ Serv, Hatfield Sch Govt, Portland, OR 97207 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU M E SHARPE INC PI ARMONK PA 80 BUSINESS PARK DRIVE, ARMONK, NY 10504 USA BN 978-0-7656-4100-7; 978-0-7656-4101-4; 978-0-7656-4099-4 PY 2014 BP 223 EP 237 PG 15 WC Public Administration SC Public Administration GA BC6YL UT WOS:000354603000017 ER PT S AU Kalia, AK Buchler, N Ungvarsky, D Govindan, R Singh, MP AF Kalia, Anup K. Buchler, Norbou Ungvarsky, Diane Govindan, Ramesh Singh, Munindar P. BE Aiello, LM McFarland, D TI Determining Team Hierarchy from Broadcast Communications SO SOCIAL INFORMATICS, SOCINFO 2014 SE Lecture Notes in Computer Science LA English DT Proceedings Paper CT 6th International Conference on Social Informatics (SocInfo) CY NOV 11-13, 2014 CL Barcelona, SPAIN SP Microsoft Res, Facebook, Yahoo Labs, Stanford, Ctr Computat Soc Sci, Barcelona Media, SocialSensor, IEEE Special Tech Community Social Networking ID CENTRALITY AB Broadcast chat messages among team members in an organization can be used to evaluate team coordination and performance. Intuitively, a well-coordinated team should reflect the team hierarchy, which would indicate that team members assigned with particular roles are performing their jobs effectively. Existing approaches to identify hierarchy are limited to data from where graphs can be extracted easily. We contribute a novel approach that takes as input broadcast messages, extracts communication patterns-as well as semantic, communication, and social features-and outputs an organizational hierarchy. We evaluate our approach using a dataset of broadcast chat communications from a large-scale Army exercise for which ground truth is available. We further validate our approach on the Enron corpus of corporate email. C1 [Kalia, Anup K.; Singh, Munindar P.] N Carolina State Univ, Raleigh, NC 27695 USA. [Buchler, Norbou; Ungvarsky, Diane] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. [Govindan, Ramesh] Univ So Calif, Los Angeles, CA 90089 USA. RP Kalia, AK (reprint author), N Carolina State Univ, Raleigh, NC 27695 USA. OI Singh, Munindar/0000-0003-3599-3893 NR 21 TC 0 Z9 0 U1 0 U2 1 PU SPRINGER-VERLAG BERLIN PI BERLIN PA HEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY SN 0302-9743 BN 978-3-319-13734-6; 978-3-319-13733-9 J9 LECT NOTES COMPUT SC PY 2014 VL 8851 BP 493 EP 507 PG 15 WC Computer Science, Information Systems; Computer Science, Theory & Methods SC Computer Science GA BC7DH UT WOS:000354775400035 ER PT S AU Ross, JA Richie, DA Park, SJ Shires, DR Henz, BJ AF Ross, James A. Richie, David A. Park, Song J. Shires, Dale R. Henz, Brian J. BE Aldinucci, M DAgostino, D Kilpatrick, P TI A Class-Structured Approach to Couple Application and Hybrid Core Parallelism SO 2014 22ND EUROMICRO INTERNATIONAL CONFERENCE ON PARALLEL, DISTRIBUTED, AND NETWORK-BASED PROCESSING (PDP 2014) SE Euromicro Conference on Parallel Distributed and Network-Based Processing LA English DT Proceedings Paper CT 22nd Euromicro International Conference on Parallel, Distributed, and Network-Based Processing (PDP) CY FEB 12-14, 2014 CL Turin, ITALY SP NVidia Corp, IBM Corp, E4 Comp Engn, Sistemi HS, Univ Turin, Comp Sci Dept, European Assoc Theoret Comp Sci, Italian Chapter, Regione Piemonte, Turismo Torino & Provincia DE OpenCL framework; GPGPU; XML; C plus AB This paper presents an application that performs multi-objective geospatial optimizations for tactical mission planning in an urban environment. Utilizing a XML-driven C++ framework developed for hybrid platforms, the application distributes computational tasks to a collection of heterogeneous OpenCL devices and achieves efficient task parallel scaling. The framework abstracts the details of the mission scenario setup, compute device architecture details, and task scheduling to enable robust extensibility in software. Performance scalability and multi-objective parameter visualization for a prototypical mission scenario are documented in this study. C1 [Ross, James A.] Dynam Res Corp, Andover, MA 01810 USA. [Richie, David A.] Brown Deer Technol, Forest Hill, MD 21050 USA. [Park, Song J.; Shires, Dale R.; Henz, Brian J.] US Army, Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Ross, JA (reprint author), Dynam Res Corp, Andover, MA 01810 USA. EM jaross@drc.com; drichie@browndeertechnology.com; song.j.park.civ@mail.mil; dale.r.shires.civ@mail.mil; brian.j.henz@mail.mil NR 20 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1066-6192 BN 978-1-4799-2728-9 J9 EUROMICRO WORKSHOP P PY 2014 BP 690 EP 696 DI 10.1109/PDP.2014.41 PG 7 WC Computer Science, Hardware & Architecture SC Computer Science GA BC6II UT WOS:000353964700101 ER PT S AU Delp, SA Allen, JL Jow, TR AF Delp, Samuel A. Allen, Joshua L. Jow, T. Richard BE Andrews, DL Nunzi, JM Ostendorf, A TI Investigation of Electrolyte Additives with LiNi0.5Mn1.5O4/Graphite Cells at High Temperature SO NANOPHOTONICS V SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Nanophotonics V CY APR 13-17, 2014 CL Brussels, BELGIUM SP SPIE, Brussels Photon Team, Fonds Wetenschappelijk Onderzoek ID LITHIUM ION BATTERIES; HIGH-VOLTAGE; ELEVATED-TEMPERATURE; LI-ION; GRAPHITE; BEHAVIOR; CATHODE; SPINEL AB The spinel-structured LiNi0.5Mn1.5O4 (LNMO) has drawn much attention as a Li-ion battery cathode material with potential electric vehicle applications due to its high operating voltage (similar to 4.7 V vs. Li/Li+) and relatively high energy density (similar to 680 Wh kg(-1)). LNMO-based cells, however, tend to suffer from capacity fading due to transition metal dissolution that is exacerbated by increased temperatures. In this study, the electrolyte additives LiDFOB, HFiP, FEC and combinations of the three were investigated to determine which additives are able to properly passivate the LNMO surface to hinder Ni and Mn dissolution and thus enable high temperature cycling with a reduced fade rate. A combination of FEC and HFiP additives yielded the best high temperature performance with a Coulombic efficiency >97% and a decreased electrolyte decomposition above 4.8 V. C1 [Delp, Samuel A.; Allen, Joshua L.; Jow, T. Richard] US Army Res Lab, Adelphi, MD 20783 USA. RP Delp, SA (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. NR 0 TC 0 Z9 0 U1 3 U2 16 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-074-7 J9 PROC SPIE PY 2014 VL 9126 BP 111 EP 118 DI 10.1149/05848.0111ecst PG 8 WC Optics; Physics, Applied SC Optics; Physics GA BA9EN UT WOS:000339318700010 ER PT J AU Gupta, RK Przekwas, AJ AF Gupta, Raj K. Przekwas, Andrzej J. BE Onate, E Oliver, X Huerta, A TI MULTISCALE MODELING OF BLAST INDUCED TRAUMATIC BRAIN INJURY: FROM WHOLE BODY RESPONSES TO BRAIN MICRODAMAGE SO 11TH WORLD CONGRESS ON COMPUTATIONAL MECHANICS; 5TH EUROPEAN CONFERENCE ON COMPUTATIONAL MECHANICS; 6TH EUROPEAN CONFERENCE ON COMPUTATIONAL FLUID DYNAMICS, VOLS II - IV LA English DT Proceedings Paper CT 11th World Congress on Computational Mechanics (WCCM) / 5th European Conference on Computational Mechanics (ECCM) / 6th European Conference on Computational Fluid Dynamics (ECFD) CY JUL 20-25, 2014 CL Barcelona, SPAIN SP Spanish Assoc Numer Methods Engn, Cambridge Univ Press, CIMNE Technologia, CRC Press, Taylor & Francis Grp, ELSEVIER, ECCOMAS, GID, iacm, John Wiley & Sons ltd, Korea Soc Computat Mech, Portable Multimedia Solutions Inflatable Struct, Springer, Collegi Enginyers Camins Canas Ports Catalunya DE Blast Wave; Traumatic Brain Injury; Mathematical Model; Biomechanics; Multiscale Model ID DESIGN AB The blast induced Traumatic Brain Injury (bTBI) has become a signature wound of therecent military operations. In spite of immense clinical and preclinical research on TBI, current understanding of injury mechanisms is limited and little is known about the short and long-term outcomes. Unlike the impact-related brain injury, the mechanisms involved in blast induced mild TBI (mTBI) have not been clearly understood. Mathematical models of human body, head and brain responses to a blast wave may provide capabilities to study brain injury mechanisms, perhaps accelerating the development of neuroprotective strategies and aiding in the development of improved personal protective equipment. The paper presents a novel multiscale, multiphysics simulation framework for modeling blast induced brain injury. We identify modeling components needed for detailed analysis of blast wave threat characterization, human body loading, body biodynamic response and body/brain biomechanics leading to potential primary injury. The paper also discusses the need for coupled modeling of primary injury biomechanics, secondary injury mechanobiology and model based assessment of injury severity scores. C1 [Gupta, Raj K.] US Army, Med Res & Mat Command, HQ, DoD Blast Injury Res Program Coordinating Off, Ft Detrick, MD 21702 USA. [Przekwas, Andrzej J.] CFD Res Corp, Huntsville, AL 35806 USA. RP Gupta, RK (reprint author), US Army, Med Res & Mat Command, HQ, DoD Blast Injury Res Program Coordinating Off, 504 Scott St, Ft Detrick, MD 21702 USA. EM raj.k.gupta.civ@mail.mil; ajp@cfdrc.com NR 37 TC 0 Z9 0 U1 2 U2 5 PU INT CENTER NUMERICAL METHODS ENGINEERING PI 08034 BARCELONA PA GRAN CAPITAN, S-N, CAMPUS NORTE UPC, MODULO C1, 08034 BARCELONA, SPAIN BN 978-84-942844-7-2 PY 2014 BP 991 EP 999 PG 9 WC Mathematics, Applied; Mechanics SC Mathematics; Mechanics GA BC5XR UT WOS:000353626501023 ER PT S AU Cam, H Monallem, P AF Cam, Hasan Monallem, Pierre GP IEEE TI Risk-Driven Aggregation and Transmission Prioritization of Cyber Alerts over Mobile Networks SO 2014 INTERNATIONAL CONFERENCE ON COMPUTING, NETWORKING AND COMMUNICATIONS (ICNC) SE International Conference on Computer Networking and Communications LA English DT Proceedings Paper CT International Conference on Computing, Networking and Communications (ICNC) CY FEB 03-06, 2014 CL Honolulu, HI DE Mobile Networks; Cyber Security; Intrusion Detection System; Alert Aggregation; Transmission Prioritization AB Alert Aggregation in mobile networks plays an important role in mitigating the adverse impact of alert generation by reducing the amount of communication and security data to be transmitted. However, it is not guaranteed that the bandwidth necessary to transmit all aggregated alerts is always available, which usually result in the transmission of a portion of the alerts, while others are discarded or queued. The transmission of insufficient alert information hinders making correct decisions about attacks, leading to compromising network security. In order to maximize the benefits of data aggregation while minimizing the impact of partial alerts, this paper presents a risk-driven real-time transmission prioritization technique for implementing lossy and lossless aggregation of cyber alerts. Lossy alert aggregation and transmission are managed adaptively by allowing the prioritization and transmission of aggregated alerts according to the risk assessment of such alerts. This paper also presents a risk-driven utilization model that further adapts the aggregation and prioritization in response to dynamic network conditions. The performance results of the proposed techniques are obtained by running simulations on data collected from a mobile network. Simulation results for the aggregation of raw alerts have shown an average reduction of 51% in data storage space and bandwidth usage. C1 [Cam, Hasan; Monallem, Pierre] Army Res Lab, Network Sci Div, Adelphi, MD 20783 USA. RP Cam, H (reprint author), Army Res Lab, Network Sci Div, Adelphi, MD 20783 USA. EM hasan.cam.civ@mail.mil; pierre.a.mouallem.ctr@mail.mil NR 11 TC 0 Z9 0 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2325-2626 BN 978-1-4799-2358-8 J9 INT CONF COMPUT NETW PY 2014 BP 58 EP 62 PG 5 WC Computer Science, Hardware & Architecture; Telecommunications SC Computer Science; Telecommunications GA BC6HZ UT WOS:000353942500012 ER PT B AU Faulkner, RS AF Faulkner, Richard S. BE Lengel, EG TI "THERE IS A LIMIT TO HUMAN ENDURANCE": THE CHALLENGES TO MORALE IN THE MEUSE-ARGONNE CAMPAIGN SO COMPANION TO THE MEUSE-ARGONNE CAMPAIGN SE Blackwell Companions to American History LA English DT Article; Book Chapter C1 [Faulkner, Richard S.] US Army Command, Mil Hist, Ft Leavenworth, KS 66027 USA. [Faulkner, Richard S.] US Mil Acad, Amer Hist, West Point, NY USA. [Faulkner, Richard S.] Gen Staff Coll, Ft Leavenworth, KS USA. RP Faulkner, RS (reprint author), US Army Command, Mil Hist, Ft Leavenworth, KS 66027 USA. NR 43 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI CHICHESTER PA THE ATRIUM, SOUTHERN GATE, CHICHESTER, WEST SUSSEX PO19 8SQ, ENGLAND BN 978-1-118-83633-0; 978-1-4443-5094-4 J9 BLACKW COMPAN AM HIS PY 2014 BP 287 EP 308 D2 10.1002/9781118836330 PG 22 WC History SC History GA BC3IA UT WOS:000351667500018 ER PT B AU Beatty, JD AF Beatty, John D. BE Lengel, EG TI WE CAN KILL THEM BUT WE CANNOT STOP THEM: EVALUATING THE MEUSE-ARGONNE CAMPAIGN SO COMPANION TO THE MEUSE-ARGONNE CAMPAIGN SE Blackwell Companions to American History LA English DT Article; Book Chapter C1 [Beatty, John D.] US Army Reserve, Ft Bragg, NC USA. NR 26 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI CHICHESTER PA THE ATRIUM, SOUTHERN GATE, CHICHESTER, WEST SUSSEX PO19 8SQ, ENGLAND BN 978-1-118-83633-0; 978-1-4443-5094-4 J9 BLACKW COMPAN AM HIS PY 2014 BP 425 EP 439 D2 10.1002/9781118836330 PG 15 WC History SC History GA BC3IA UT WOS:000351667500026 ER PT B AU Neiberg, MS AF Neiberg, Michael S. BE Lengel, EG TI LESSONS LEARNED SO COMPANION TO THE MEUSE-ARGONNE CAMPAIGN SE Blackwell Companions to American History LA English DT Article; Book Chapter C1 US Army War Coll, Dept Natl Secur & Strategy, Hist, Carlisle, PA 17013 USA. RP Neiberg, MS (reprint author), US Army War Coll, Dept Natl Secur & Strategy, Hist, Carlisle, PA 17013 USA. NR 21 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI CHICHESTER PA THE ATRIUM, SOUTHERN GATE, CHICHESTER, WEST SUSSEX PO19 8SQ, ENGLAND BN 978-1-118-83633-0; 978-1-4443-5094-4 J9 BLACKW COMPAN AM HIS PY 2014 BP 457 EP 471 D2 10.1002/9781118836330 PG 15 WC History SC History GA BC3IA UT WOS:000351667500028 ER PT B AU Snell, MA AF Snell, Mark A. BE SheehanDean, A TI BATTLE OF FREDERICKSBURG SO COMPANION TO THE U.S. CIVIL WAR, VOLS I AND II SE Blackwell Companions to American History LA English DT Article; Book Chapter C1 [Snell, Mark A.] Shepherd Univ, George Tyler Moore Ctr Study Civil War, Shepherdstown, WV 25443 USA. [Snell, Mark A.] Shepherd Univ, Hist, Shepherdstown, WV 25443 USA. [Snell, Mark A.] US Mil Acad, Hist, West Point, NY 10996 USA. RP Snell, MA (reprint author), Shepherd Univ, George Tyler Moore Ctr Study Civil War, Shepherdstown, WV 25443 USA. NR 33 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI CHICHESTER PA THE ATRIUM, SOUTHERN GATE, CHICHESTER, WEST SUSSEX PO19 8SQ, ENGLAND BN 978-1-118-60907-1; 978-1-4443-5131-6 J9 BLACKW COMPAN AM HIS PY 2014 BP 231 EP 239 D2 10.1002/9781118609071 PG 9 WC History SC History GA BC3IP UT WOS:000351671600014 ER PT B AU Keller, CB AF Keller, Christian B. BE SheehanDean, A TI CHANCELLORSVILLE CAMPAIGN SO COMPANION TO THE U.S. CIVIL WAR, VOLS I AND II SE Blackwell Companions to American History LA English DT Article; Book Chapter C1 US Army War Coll, Hist, Carlisle, PA 17013 USA. RP Keller, CB (reprint author), US Army War Coll, Hist, Carlisle, PA 17013 USA. NR 38 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI CHICHESTER PA THE ATRIUM, SOUTHERN GATE, CHICHESTER, WEST SUSSEX PO19 8SQ, ENGLAND BN 978-1-118-60907-1; 978-1-4443-5131-6 J9 BLACKW COMPAN AM HIS PY 2014 BP 262 EP 279 D2 10.1002/9781118609071 PG 18 WC History SC History GA BC3IP UT WOS:000351671600016 ER PT J AU Tzeng, JT Hsieh, KT AF Tzeng, Jerome T. Hsieh, Kuo-Ta BE Fair, HD TI Electromagnetic Field Effect and Analysis of Composite Structure SO 2014 17TH INTERNATIONAL SYMPOSIUM ON ELECTROMAGNETIC LAUNCH TECHNOLOGY (EML) LA English DT Proceedings Paper CT 17th IEEE International Symposium on Electromagnetic Launch Technology (EML) CY JUL 07-11, 2014 CL Inst Strateg & Innovat Technologies, San Diego, CA SP IEEE, IEEE Nucl & Plasma Sci Soc, Gen Atom, BAE Syst, China Electrotechn Soc, AUSTAL HO Inst Strateg & Innovat Technologies AB The electromagnetic and thermal response of composites subjected to magnetic fields is simulated by solving Maxwell and heat transfer equations simultaneously. The developed analysis accounts for the anisotropic nature of the electrical and thermal properties in three dimensions. A finite element code is developed to predict the response of composite structures subjected to transient magnetic fields. The analysis has been validated against a closed form solution and applied to simulate the induction heating process of composite cylinders. The developed analysis can be applied to the design of modern electrical weapons and used to simulate composite manufacturing processes such as induction cure. C1 [Tzeng, Jerome T.] US Army, Res Lab, Aberdeen Proving Ground, MD 21005 USA. [Hsieh, Kuo-Ta] Univ Texas Austin, Austin, TX 78759 USA. RP Tzeng, JT (reprint author), US Army, Res Lab, Aberdeen Proving Ground, MD 21005 USA. NR 5 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-2733-3 PY 2014 PG 5 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA BC5YK UT WOS:000353645400018 ER PT J AU Zhao, X Fan, K Zhang, J Seren, HR Metcalfe, GD Wraback, M Averitt, RD Zhang, X AF Zhao, X. Fan, K. Zhang, J. Seren, H. R. Metcalfe, G. D. Wraback, M. Averitt, R. D. Zhang, X. GP IEEE TI DESIGN, FABRICATION AND CHARACTERIZATION OF TUNABLE PERFECT ABSORBER ON FLEXIBLE SUBSTRATE SO 2014 IEEE 27TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS) LA English DT Proceedings Paper CT 27th IEEE International Conference on Micro Electro Mechanical Systems (MEMS) CY JAN 26-30, 2014 CL San Francisco, CA SP IEEE, Robot & Automat Soc ID METAMATERIALS AB This paper reports our recent progress on a highly flexible dynamic perfect absorber at terahertz (THz) frequencies. Metamaterial unit cells were patterned on thin GaAs patches, which were fashioned in an array on a 5 mu m polyimide substrate via transfer printing technique, and the backside of the substrate was coated with gold film as ground plane. Optical- pump THz- probe reflection measurements show that the absorptivity at resonance frequency of 1.58THz can be tuned up to 57% through photo- excitation of free carriers in GaAs layers in presence of 800nm pump beam. Our flexible tunable MM perfect absorber exhibits potential applications in energy harvesting, imaging and stealth coating. C1 [Zhao, X.; Fan, K.; Zhang, J.; Seren, H. R.; Averitt, R. D.; Zhang, X.] Boston Univ, Boston, MA 02215 USA. [Metcalfe, G. D.; Wraback, M.] US Army Res Lab, Adelphi, MD USA. RP Zhang, X (reprint author), Boston Univ, Boston, MA 02215 USA. EM xinz@bu.edu RI Fan, Kebin/B-2984-2012 OI Fan, Kebin/0000-0002-0275-0871 NR 15 TC 2 Z9 2 U1 1 U2 8 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-3508-6 PY 2014 BP 84 EP 87 PG 4 WC Engineering, Electrical & Electronic SC Engineering GA BC4AO UT WOS:000352217500022 ER PT B AU Jabbour, RE Deshpande, SV Snyder, AP Wade, MM AF Jabbour, Rabih E. Deshpande, Samir V. Snyder, A. Peter Wade, Mary M. BE Jonsson, P Olofsson, G Tjarnhage, T TI Mass Spectrometry Techniques in the Analysis of Bioaerosols: Development and Advancement SO BIOAEROSOL DETECTION TECHNOLOGIES SE Integrated Analytical Systems LA English DT Article; Book Chapter ID ASSISTED-LASER-DESORPTION/IONIZATION; BACILLUS-ATROPHAEUS SPORES; WHOLE BACTERIAL-CELLS; GAS-CHROMATOGRAPHY; DESORPTION IONIZATION; AEROSOL-PARTICLES; MURAMIC ACID; FATTY-ACIDS; PYROLYTIC METHYLATION; ATMOSPHERIC AEROSOLS C1 [Jabbour, Rabih E.; Snyder, A. Peter; Wade, Mary M.] US Army Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD 21010 USA. [Deshpande, Samir V.] Sci & Technol Corp, Edgewood, MD 21040 USA. RP Jabbour, RE (reprint author), US Army Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD 21010 USA. EM rabih.e.jabbour.civ@mail.mil NR 68 TC 0 Z9 0 U1 0 U2 3 PU SPRINGER PI NEW YORK PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES BN 978-1-4419-5582-1; 978-1-4419-5581-4 J9 INTEGR ANAL SYST PY 2014 BP 169 EP 202 DI 10.1007/978-1-4419-5582-1_9 D2 10.1007/978-1-4419-5582-1 PG 34 WC Biotechnology & Applied Microbiology; Chemistry, Analytical SC Biotechnology & Applied Microbiology; Chemistry GA BC4YS UT WOS:000353049300010 ER PT J AU Tan, J Baron, D Dai, LY AF Tan, Jin Baron, Dror Dai, Liyi GP IEEE TI Signal Estimation with Low Infinity-Norm Error by Minimizing the Mean p-Norm Error SO 2014 48TH ANNUAL CONFERENCE ON INFORMATION SCIENCES AND SYSTEMS (CISS) LA English DT Proceedings Paper CT 48th Annual Conference on Information Sciences and Systems (CISS) CY MAR 19-21, 2014 CL Princeton Univ, Princeton, NJ SP IEEE Informat Theory Soc, Princeton Univ, Dept Elect Engn HO Princeton Univ DE Gaussian mixture; l(infinity)-norm error; linear mixing systems; parallel scalar Gaussian channels; Wiener filters ID ROBUST REGRESSION; SPREAD CDMA; ASYMPTOTICS; COMPUTATION AB We consider the problem of estimating an input signal from noisy measurements in both parallel scalar Gaussian channels and linear mixing systems. The performance of the estimation process is quantified by the l(infinity)-norm error metric (worst case error). Our previous results have shown for independent and identically distributed (i.i.d.) Gaussian mixture input signals that, when the input signal dimension goes to infinity, the Wiener filter minimizes the l(infinity)-norm error. However, the input signal dimension is finite in practice. In this paper, we estimate the finite dimensional input signal by minimizing the mean l(p)-norm error. Numerical results show that the l(p)-norm minimizer outperforms the Wiener filter, provided that the value of p is properly chosen. Our results further suggest that the optimal value of p increases with the signal dimension, and that for i.i.d. Bernoulli-Gaussian input signals, the optimal p increases with the percentage of nonzeros. C1 [Tan, Jin; Baron, Dror] N Carolina State Univ, Dept Elect & Comp Engn, Raleigh, NC 27695 USA. [Dai, Liyi] US Army Res Off, Div Comp Sci, Res Triangle Pk, NC 27709 USA. RP Tan, J (reprint author), N Carolina State Univ, Dept Elect & Comp Engn, Raleigh, NC 27695 USA. EM jtan@ncsu.edu; barondror@ncsu.edu; liyi.dai.civ@mail.mil NR 30 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-3001-2 PY 2014 PG 5 WC Computer Science, Information Systems; Computer Science, Theory & Methods; Information Science & Library Science SC Computer Science; Information Science & Library Science GA BC3UL UT WOS:000351998300007 ER PT J AU Schafer, G Mannix, G Watson, J AF Schafer, Gina Mannix, Greg Watson, Jerry BE Ames, RG Boeka, RD TI SHAPED CHARGE JET INTERACTION WITH NITROCELLULOSE PROPELLANT SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB The interaction of a shaped charge jet impacting energetic materials is often characterized by a rapid release of chemical energy to the surrounding environment. Understanding the effectual parameters and predicting the ensuing energy release are crucial to the design and development of systems or facilities that house such energetics. Of particular interest, the response of propellants to primary and secondary jet interactions at low loading densities offers researchers the opportunity to explore complex sub-detonative outcomes. This paper addresses (1) a decomposition of possibilities, (2) an experimental technique to isolate parameters, and (3) pressure responses for a nitrocellulose-based propellant subject to direct jet interaction and jet-originated spall fragment interaction. These experimental results allow for a more fundamental understanding of the energy response across the temporal domain offering insights foundational to the development of predictive techniques. C1 [Schafer, Gina; Mannix, Greg; Watson, Jerry] US Army, Res Lab, Aberdeen Proving Ground, MD 21001 USA. RP Schafer, G (reprint author), US Army, Res Lab, Aberdeen Proving Ground, MD 21001 USA. NR 3 TC 0 Z9 0 U1 0 U2 4 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 220 EP 229 PG 10 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700028 ER PT J AU Rozumov, E Thompson, D Adam, CP Wyckoff, J Manning, TG Grau, H Caravaca, E Reilly, JO AF Rozumov, Eugene Thompson, David Adam, Carlton P. Wyckoff, Jeffrey Manning, Thelma G. Grau, Henry Caravaca, Elbert Reilly, John O' BE Ames, RG Boeka, RD TI A NOVEL 105 MM FOUR ZONE SOLUTION PROPELLANT FOR PROPELLING HEAVY PROJECTILES SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB Under the Scalable Technology for Adaptive Response Army Technology Objective (STAR ATO) effort, the Armaments Research Development and Engineering Center (ARDEC) developed a novel propellant for the 105 mm gun system that employs projectiles that are 20% heavier than standard projectiles. Thermodynamic modeling and simulation was utilized in the early stages to develop several high energy formulations. Those formulations were then manufactured and closed bombed to determine their burn rates. The burn rates and thermodynamic data were then utilized in IBHVG2 to optimize the grain and web geometries for the 105mm gun system. Finally, one candidate formulation was produced and test fired at Yuma Proving Grounds in the 105mm gun system. The ARDEC propellant is a safe, stable, propellant with a flat temperature profile that easily met and exceeded the muzzle velocity (500 m/sec minimum), chamber pressure (49,500 psi maximum), and zone overlap requirements (10% minimum) for the new heavier projectiles. Even higher velocities can be achieved by increasing the charge loading density, owing to the low chamber pressure produced by the ARDEC propellant. The ARDEC propellant is also a 4 zone solution leading to more simplified logistics with respect to the multi-zone bag charges currently employed in the 105mm system. C1 [Rozumov, Eugene; Thompson, David; Adam, Carlton P.; Wyckoff, Jeffrey; Manning, Thelma G.; Grau, Henry; Caravaca, Elbert; Reilly, John O'] US Army ARDEC, Picatinny Arsenal, NJ 07806 USA. RP Rozumov, E (reprint author), US Army ARDEC, Picatinny Arsenal, NJ 07806 USA. NR 5 TC 0 Z9 0 U1 1 U2 1 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 413 EP 419 PG 7 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700050 ER PT J AU Rozumov, E Caravaca, E Grau, H Wyckoff, J Laquidara, J Manning, T Drummond, J Brooks, J Pulver, R AF Rozumov, Eugene Caravaca, Elbert Grau, Henry Wyckoff, Jeffrey Laquidara, Joseph Manning, Thelma Drummond, Jim Brooks, Jeannette Pulver, Robert BE Ames, RG Boeka, RD TI DETERRING OF DOUBLE BASED BALL POWDER (R) WITH INORGANIC AND ORGANIC SALTS TO REPLACE DIBUTYL-PHTHALATE AND PREVENT DETERRENT MIGRATION SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB In this effort, the Armaments Research Development and Engineering Center (ARDEC), along with Saint Mark's Ball & Powder, examined the effects of surface coating, and deterring double base BALL POWDER (R) Propellants. We employed a variety of organic and inorganic salts as either a surface coating or as a deterrent and compared them to grains deterred with dibutyl-phthalate (DBP). DBP is a toxic organic compound that is being slowly phased out of production, and it has been shown to migrate over time, leading to decreases in ballistic efficiency of ball powders that have been stored for extended periods of time. All samples were closed bombed to determine their relative force (RF) and relative quickness (RQ) in comparison to the DBP deterred ball powders and ensure that they are safe to fire in a 7.62mm gun. All candidates that did not substantially exceed the RF and RQ of the baseline powders were then fired in 7.62mm rounds. Herein we present the ballistic data for these gun firings. One inorganic sample demonstrated itself to be a drop in replacement for DBP, because its ballistic profile matched perfectly to that of the DBP baseline powder, even at a loading density 15% lower than that of the DBP baseline powder. Furthermore, since the sample is inorganic, it should not migrate through the grain over time, thereby maintaining ballistic efficiency even after prolonged storage. C1 [Rozumov, Eugene; Caravaca, Elbert; Grau, Henry; Wyckoff, Jeffrey; Laquidara, Joseph; Manning, Thelma] US Army ARDEC, Picatinny Arsenal, NJ 07806 USA. [Drummond, Jim; Brooks, Jeannette; Pulver, Robert] St Marks Powder, Crawfordville, FL 32327 USA. RP Rozumov, E (reprint author), US Army ARDEC, Picatinny Arsenal, NJ 07806 USA. NR 4 TC 0 Z9 0 U1 0 U2 1 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 420 EP 427 PG 8 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700051 ER PT J AU Ritter, JJ AF Ritter, John J. BE Ames, RG Boeka, RD TI BARREL LEADE EFFECTS ON 5.56-MM INTERIOR BALLISTICS SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB The US Army Research Laboratory (ARL) has designed a custom small caliber gun breech capable of measuring the force output seen at the primer during the interior ballistic (IB) event. This novel measurement technique provides insight into the early time (0 - 100 mu s) IB performance of a cartridge otherwise overlooked by standard mid-case pressure measurements. Furthermore, an extremely short barrel gun is employed with high speed imaging to capture first motion of the projectile. Together these diagnostic tools provide researchers with state-of-the-art characterization capabilities of early time IB events including primer performance and primer-propellant interactions. This paper will investigate the influence of barrel leade (free bore) on the cartridge's IB performance. C1 US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Ritter, JJ (reprint author), US Army Res Lab, B390 RDRL-WML-D, Aberdeen Proving Ground, MD 21005 USA. NR 5 TC 1 Z9 1 U1 0 U2 4 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 428 EP 433 PG 6 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700052 ER PT J AU Beyer, RA Ritter, JJ AF Beyer, Richard A. Ritter, John J. BE Ames, RG Boeka, RD TI MEASUREMENTS OF EARLY BULLET MOTION AT 5.56 MM AND 7.62 MM SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB A novel technique for quantifying the initial motion of projectiles (5.56 mm and 7.62 mm) in unmodified small caliber ammunition is demonstrated. Evidence that the primer in these rounds launches the bullet into the engraving is presented. The impulse resulting from the primers (No. 41 and No. 34, respectively) is measured and compared to the bullet momentum. Values for velocity and acceleration at early time are shown which are consistent with intuition. Other consequences of the accurate measurements of the motion and associated pressure include comparing work done on the bullet to the kinetic energy as a function of position or time. C1 [Beyer, Richard A.] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Beyer, RA (reprint author), US Army Res Lab, RDRL-WML-D Bldg 390, Aberdeen Proving Ground, MD 21005 USA. NR 6 TC 1 Z9 1 U1 1 U2 3 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 434 EP 443 PG 10 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700053 ER PT J AU Manning, T Wyckoff, J Adam, C Rozumov, E Klingaman, K Panchal, V Laquidara, J Fair, M Bolognini, J Luhmann, K Velarde, S Knott, C Piraino, SM Boyd, K AF Manning, Thelma Wyckoff, Jeffrey Adam, Carlton Rozumov, Eugene Klingaman, Kenneth Panchal, Viral Laquidara, Joseph Fair, Mike Bolognini, John Luhmann, Keith Velarde, Steve Knott, Christine Piraino, Stephanie M. Boyd, Kevin BE Ames, RG Boeka, RD TI FORMULATION DEVELOPMENT AND CHARACTERIZATION OF CELLULOSE ACETATE NITRATE BASED PROPELLANTS FOR IMPROVED INSENSITIVE MUNITIONS PROPERTIES SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB Cellulose acetate nitrate (CAN) was used as an insensitive energetic binder to improve the insensitive munitions (IM) properties of gun propellants to replace the M1 propellant used in 105mm artillery charges. CAN contains the energetic nitro groups found in nitrocellulose (NC), but also acetyl functionalities, which lowered the polymer's sensitivity to heat and shock, and therefore improved its IM properties relative to NC. The formulation, development and small-scale characterization testing of several CAN-based propellants were done. The formulations, using insensitive energetic solid fillers and high-nitrogen modifiers in place of nitramine were completed. The small scale characterization testing, such as closed bomb testing, small scale sensitivity, thermal stability, and chemical compatibility were done. The mechanical response of the propellants under high-rate uni-axial compression at, hot, cold, and ambient temperatures were also completed. Critical diameter testing, hot fragment conductive ignition (HFCI) tests were done to evaluate the propellants' responses to thermal and shock stimuli. Utilizing the propellant chemical composition, theoretical predictions of erosivity were completed. All the small scale test results were utilized to down-select the promising CAN based formulations for large scale demonstration testing such as the ballistic performance and fragment impact testing in the 105mm M67 artillery charge configurations. The test results completed in the small and large scale testing are discussed. C1 [Manning, Thelma; Wyckoff, Jeffrey; Adam, Carlton; Rozumov, Eugene; Klingaman, Kenneth; Panchal, Viral; Laquidara, Joseph; Fair, Mike; Bolognini, John; Luhmann, Keith] US Army RDECOM ARDEC, Picatinny Arsenal, NJ USA. [Knott, Christine] Naval Surface Warhead Ctr, Indian Head, MD USA. [Piraino, Stephanie M.; Boyd, Kevin] Army Res Lab, Aberdeen Proving Ground, MD USA. RP Manning, T (reprint author), US Army RDECOM ARDEC, Picatinny Arsenal, NJ USA. NR 17 TC 0 Z9 0 U1 1 U2 4 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 471 EP 485 PG 15 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700057 ER PT J AU Blot, A Chaplin, R AF Blot, A. Chaplin, R. BE Ames, RG Boeka, RD TI COUPLING OF A LUMPED MASS INTERIOR BALLISTIC CODE WITH THE STRUCTURAL FINITE ELEMENT CODE ABAQUS SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB During the ammunition design phase the evaluation of structural survivability during gun launch is a critical parameter. Finite Element Analysis (FEA) is a useful tool for evaluation as it allows designers to visualize phenomena that would otherwise be impossible to capture through live fire testing methods. Current methods in FEA launch analysis usually involves using a Pressure-Time (PT) curve obtained from live fire testing as a boundary condition to drive the ammunition down the gun barrel. While this is a good approximation for the structural response, these "dummy" PT curves cannot react to or accurately model real life phenomena such as over or under size bullets, propellant changes, or bore obstructions because they are completely uncoupled to the physics in the model. This paper studies the results of coupling ARDECIB, a lumped mass interior ballistic code developed at ARDEC similar to IBHVG3, with the FEA code ABAQUS. In this approach pressure data is generated, within ARDECIB by modeling burning propellants, and passed into the FEA code at the same time projectile travel outputs from FEA are passed back to the interior ballistic code. Pressure time curves generated from the linked code are compared with pure IBHVG3 codes and real life test data. A discussion on this code's value as a predictive tool with limited test data shall be presented. C1 [Blot, A.] US Army ARDEC, Anal & Evaluat Div, Army RDECOM ARDEC, Army RDAR MEF E, Picatinny Arsenal, NJ 07806 USA. [Chaplin, R.] US Army ARDEC, Small Caliber Modeling & Simulat Grp, Army RDECOM ARDEC, RDAR MEM I, Picatinny Arsenal, NJ 07806 USA. RP Blot, A (reprint author), US Army ARDEC, Anal & Evaluat Div, Army RDECOM ARDEC, Army RDAR MEF E, Picatinny Arsenal, NJ 07806 USA. NR 2 TC 0 Z9 0 U1 0 U2 1 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 521 EP 531 PG 11 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700061 ER PT J AU Fresconi, F DeSpirito, J Celmins, I AF Fresconi, Frank DeSpirito, James Celmins, Ilmars BE Ames, RG Boeka, RD TI FLIGHT PERFORMANCE OF A MAN PORTABLE GUIDED PROJECTILE CONCEPT SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc ID NAVIER-STOKES PREDICTIONS; JET INTERACTION; STABILITY; GUIDANCE AB Future enhanced lethal effects at the squad level likely include precision guided technologies. The focus of this study is maneuvering projectiles launched from man portable weapon systems. A novel guided projectile concept is proposed for achieving control authority requirements in the challenging environment of low dynamic pressure, small size, high launch loads, spin-stabilization, and low cost. This new maneuver concept is based on a rotating wing actuator. Experimental and advanced computational aerodynamics techniques were applied to enable flight simulation. Maneuvering flight simulations demonstrated that this concept may afford enough course correction to compensate for ballistic delivery errors. C1 [Fresconi, Frank; DeSpirito, James; Celmins, Ilmars] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Fresconi, F (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. NR 37 TC 0 Z9 0 U1 1 U2 2 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 689 EP 699 PG 11 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700079 ER PT J AU Minnicino, MA AF Minnicino, Michael A. BE Ames, RG Boeka, RD TI COUPLED ROLL RATE-BENDING BEHAVIOR OF LONG-ROD PENETRATORS SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB Penetrator flexure is typically viewed as a launch dynamics structural issue that is addressed during the development of long rod penetrators. Rod flexure is also of interest from an exterior ballistics standpoint because the aerodynamic forces and moments acting on the projectile can induce flexure resonance resulting in reduced accuracy and reduced effective range. Aerodynamic experiments have demonstrated long rod penetrators can be subjected to a visible amount of in-flight flexure. Experimental data indicated that the rod's initial bending plane orientation relative to the global coordinate frame appears to precess at a rate much less that the projectile roll rate. In this paper, structural simulations are developed and presented in order to expound upon the precession phenomenon established by the experimental data. For low roll rate penetrators, the simulations show that the rod's bending plane remains largely fixed in the global coordinate system. C1 US Army Res Lab, RDRL WML G, Aberdeen Proving Ground, MD 21005 USA. RP Minnicino, MA (reprint author), US Army Res Lab, RDRL WML G, Aberdeen Proving Ground, MD 21005 USA. NR 4 TC 0 Z9 0 U1 0 U2 3 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 730 EP 741 PG 12 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700083 ER PT J AU Celmins, I Fresconi, FE Nelson, BP AF Celmins, Ilmars Fresconi, Frank E. Nelson, Bryant P. BE Ames, RG Boeka, RD TI ACTUATOR CHARACTERIZATION OF A MAN PORTABLE PRECISION MANEUVER CONCEPT SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB The US Army Research Laboratory is conducting research to explore technologies that may be suitable for maneuvering man-portable munitions. Current research is focused on rotary actuators with spin-stabilized munitions. This is in contrast to linear (reciprocating) actuators which would need to constantly change direction, resulting in large accelerations and large forces, thereby driving up the actuator power. A rotational actuator would be operating at a fairly constant rotation rate once it is up to speed, resulting in much lower power requirements. Actuator experiments conducted over a variety of conditions validate dynamic models of the actuator and supply data necessary for model parameter estimation. Actuator performance metrics of spin rate response, friction, and power requirements were derived from the data. This study indicates that this class of maneuver concepts can be driven with these actuators. These results enable actuator design and multi-disciplinary simulation of refined maneuver concepts for a specific application. C1 [Celmins, Ilmars; Fresconi, Frank E.] US Army Res Lab, RDRL WML E, Aberdeen Proving Ground, MD 21005 USA. [Nelson, Bryant P.] Bowhead Sci & Technol, Belcamp, MD 21017 USA. RP Celmins, I (reprint author), US Army Res Lab, RDRL WML E, Aberdeen Proving Ground, MD 21005 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 742 EP 745 PG 4 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700084 ER PT J AU Brown, TG Harkins, T Don, M Hall, R Garner, J Davis, B AF Brown, T. Gordon Harkins, Thomas Don, Michael Hall, Rex Garner, James Davis, Bradford BE Ames, RG Boeka, RD TI DEVELOPMENT AND DEMONSTRATION OF A NEW CAPABILITY FOR AERODYNAMIC CHARACTERIZATION OF MEDIUM CALIBER PROJECTILES SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB Observations of projectile free flight motion are used in making estimates of the aerodynamic coefficients in the differential equations describing that motion. Since the last years of the 20th century, state measurements of large caliber projectiles throughout flight have been successfully made using onboard instrumentation and telemetry systems. Because a single flight can span a wide range of mach numbers and angular motions, analysis of these data greatly enhances the ability to obtain aerodynamic characterization of projectiles in a timely fashion at reduced costs. Beginning in 2012, the Army Research Laboratory undertook to design, build, and demonstrate via flight experiments an instrumentation/ telemetry system to achieve a similar capability for medium caliber projectiles. Hardware and software development and packaging efforts necessary to this successful effort will be described and flight experiment data will be shown and analyzed. C1 [Brown, T. Gordon; Don, Michael; Hall, Rex; Garner, James; Davis, Bradford] US Army, Res Lab, Aberdeen Proving Ground, MD 21005 USA. [Harkins, Thomas] Oak Ridge Associated Univ, Belcamp, MD 21017 USA. RP Brown, TG (reprint author), US Army, Res Lab, Aberdeen Proving Ground, MD 21005 USA. NR 9 TC 0 Z9 0 U1 0 U2 0 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 780 EP 791 PG 12 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700088 ER PT J AU Maley, J Fresconi, F Fairfax, L AF Maley, James Fresconi, Frank Fairfax, Luisa BE Ames, RG Boeka, RD TI GPS-DENIED NAVIGATION FOR ARTILLERY PROJECTILES EQUIPPED WITH A COURSE-CORRECTING FUZE SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc ID GUIDANCE; FLIGHT; CANARDS; DESIGN AB This report investigates GPS-denied inertial navigation using low-cost sensors for artillery projectiles equipped with course-correcting fuzes by introducing unique flight dynamics into the estimation algorithms. Low-cost sensor selection criteria specific to gyroscopically-stabilized projectiles are proposed. High fidelity modeling and simulation for course-correcting fuze projectiles underpin estimation algorithm development and assessment. The aided navigation techniques are the principal contribution of this report. An overarching position and velocity estimator is formulated along with estimators for attitude and sensor nuisance parameters embedded within this framework. Low cost sensors are accommodated in the algorithm by comparing sensor stimuli with expectations based on known, repeatable flight dynamics to provide in-flight calibration. Monte Carlo simulations were conducted. Results provide the relationship between the time-of-flight that external measurements are received and the navigation and overall weapon system performance. These limited data indicate that guided system accuracy improves by a factor of 2 over ballistic accuracy if external measurements from radar or GPS are provided around 10 sec into the flight. When external measurements are provided past halfway into flight the performance improves to near GPS-only levels. C1 [Maley, James; Fresconi, Frank; Fairfax, Luisa] US Army, Res Lab, RDRL WML F, Aberdeen Proving Ground, MD 21005 USA. RP Maley, J (reprint author), US Army, Res Lab, RDRL WML F, B459, Aberdeen Proving Ground, MD 21005 USA. NR 32 TC 0 Z9 0 U1 1 U2 3 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 792 EP 803 PG 12 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700089 ER PT J AU Celmins, I AF Celmins, Ilmars BE Ames, RG Boeka, RD TI SUBSCALE SIMULATION OF SABOT SEPARATION SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB A recent test program required firing a saboted projectile through a spark shadowgraph range. The sabot design included a pusher assembly that would follow directly behind the projectile in the early portion of the flight. Initial testing showed that a subscale launch package assembled from parts built from plastic via rapid prototyping (3-D printing) and fired from a 2 '' diameter air gun exhibited similar sabot discard performance to the full-size projectile. Subsequent evaluation of several sabot concepts revealed that the best design had one of the four sabot petals firmly attached to the pusher assembly using an aluminum rod (stripper pole), so that the discarding sabot petal pulled the pusher assembly off of the line of fire. The modified assembly was fabricated and successfully tested in the full-scale 8 '' gun. C1 US Army, Res Lab, RDRL WML E, Aberdeen Proving Ground, MD 21005 USA. RP Celmins, I (reprint author), US Army, Res Lab, RDRL WML E, Aberdeen Proving Ground, MD 21005 USA. NR 1 TC 0 Z9 0 U1 0 U2 3 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 860 EP 869 PG 10 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700096 ER PT J AU Price, CD Rushing, TS AF Price, Carey D. Rushing, Todd S. BE Ames, RG Boeka, RD TI STATISTICAL METHOD FOR DETERMINING GOVERNING PROPERTIES OF HIGH-VELOCITY POLYMER PENETRATIONS SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB Determination of the ballistic limit of candidate armor materials is often a purely experimental process involving little more than trial and error. Attempts to predict the ballistic response of novel materials such as polymers are often based on assumed material properties that are poorly understood or have little influence on the overall performance of the material. One such material property that is often overlooked is tan delta, the ratio of a polymer's loss modulus to storage modulus. These values are both rate and temperature dependent and were proposed to dominate the failure of certain ballistic regimes by Roland et al.([1]) The focus of this study was to determine what, if any, correlation exists between tan d and ballistic limit in the specific case of low-mass (2gn), high-velocity (similar to 1800 m/s) projectiles impacting a range of polymers. In the absence of a direct correlation between tan d and ballistic limit, the study shifted focus to the material properties that dominate failure in these events. Target samples of various commercially available plastics were subjected to laboratory ballistics testing, and the ballistic limit (V-50) was determined for each material. The results of the ballistics tests were then compared to the tan d, loss modulus, and storage modulus of each material as well as other material properties to determine the correlations present and quantify the contribution of each on high-speed, low-mass projectile penetration into polymers. C1 [Price, Carey D.; Rushing, Todd S.] US Army, Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. RP Price, CD (reprint author), US Army, Engineer Res & Dev Ctr, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. NR 18 TC 0 Z9 0 U1 0 U2 0 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 886 EP 897 PG 12 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700099 ER PT J AU Fountzoulas, CG Strassburger, E AF Fountzoulas, Costas G. Strassburger, Elmar BE Ames, RG Boeka, RD TI NUMERICAL STUDY OF DAMAGE PROPAGATION AND DYNAMIC FRACTURE IN SAPPHIRE SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB Sapphire, a single crystal of aluminum oxide, is of interest to U.S. Army and one of the candidate materials for use as the hard strike face of a transparent laminated armor. Strassburger et al studied monolithic single crystal sapphire plates (100 mm x 100 mm x 10 mm) in crystallographically controlled directions, such as the (0001) basal plane, 450 m/s with both steel solid cylinders and spheres. The edge-on impact (EOI) ballistic behavior of these plates is simulated using the non-linear AUTODYN commercial package by using three-dimensional, 180 degrees (reflective) modeling and simulation. This study reports on the ability and the modification of existing strength and failure material models of Al2O3 to be used as sapphire models for duplication of the experimental fracture and wave propagation in sapphire of different crystal orientation with respect to the line of impact. C1 [Fountzoulas, Costas G.] US Army, Res Lab, Weap & Mat Res Directorate, RDRL WMM B, Aberdeen Proving Ground, MD 21005 USA. [Strassburger, Elmar] EMI, Fraunhofer Inst Kurtzeitdynam, D-79400 Kanderrn, Germany. RP Fountzoulas, CG (reprint author), US Army, Res Lab, Weap & Mat Res Directorate, RDRL WMM B, Aberdeen Proving Ground, Aberdeen Proving Ground, MD 21005 USA. NR 8 TC 0 Z9 0 U1 0 U2 0 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 921 EP 930 PG 10 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700102 ER PT J AU Meyer, CS AF Meyer, Christopher S. BE Ames, RG Boeka, RD TI NUMERICAL EXPLORATION OF THE TERMINAL EFFECTS OF MULTIPLE PENETRATORS PERFORATING CONCRETE SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc ID TARGETS; PROJECTILES AB To explore the terminal effects of multiple impacts into a single concrete target, modeling and simulation was performed at the U.S. Army Research Laboratory. These simulations employ the CTH shock physics code to build geometry and perform the calculations. This work explores the results predicted by the Holmquist-Johnson-Cook concrete model, which uses a coupled equation of state and strength model. Results explored include the effect that spacing between penetrators has on penetrator residual velocity. Also explored is the effect of two different impact timings, which bound the problem: simultaneous impact and successive impact. This paper presents the modeling approach used, validation of numerical simulations, and results illustrating the effect of penetrator spacing on residual velocity. C1 US Army Res Lab, RDRL WML H, Aberdeen Proving Ground, MD 21005 USA. RP Meyer, CS (reprint author), US Army Res Lab, RDRL WML H, Aberdeen Proving Ground, MD 21005 USA. NR 20 TC 0 Z9 0 U1 2 U2 6 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 1105 EP 1116 PG 12 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700121 ER PT J AU Aydelotte, B Schuster, B AF Aydelotte, Brady Schuster, Brian BE Ames, RG Boeka, RD TI A COMPUTATIONAL STUDY OF THE ARL GLASS MODEL AND ITS PREDICTIONS OF BALLISTIC PENETRATION AND FRACTURE CONOID DEVELOPMENT SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc ID SPHERE; CRACK AB The failure of silicate glass during ballistic impact is a complex series of events which present a significant challenge to constitutive models. Numerical simula-tions of borosilicate glass behavior using the ARL glass model are conducted and compared with published experimental results, and found to be mesh sensitive. The triaxial failure strengths within the ARL glass model are volume scaled and given Weibull distributions. The effect of the statistical perturbation and other fea-tures are explored. It is found that the ARL glass model, when given a stochastic parameterization, is able to capture material variability and scale effects though the mesh sensitivity is not improved. The ARL glass model is able to capture many trends in published ballistic data but not time- resolved fracture behavior. C1 [Aydelotte, Brady; Schuster, Brian] US Army Res Lab, RDRL WML H, Aberdeen Proving Ground, MD 21005 USA. RP Aydelotte, B (reprint author), US Army Res Lab, RDRL WML H, Aberdeen Proving Ground, MD 21005 USA. NR 16 TC 0 Z9 0 U1 0 U2 0 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 1117 EP 1128 PG 12 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700122 ER PT J AU Vargas-Gonzalez, LR Gurganus, JC AF Vargas-Gonzalez, Lionel R. Gurganus, James C. BE Ames, RG Boeka, RD TI INFLUENCE OF COMPOSITE ARCHITECTURE ON STRESS TRANSMITTANCE IN ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE COMPOSITE ARMOR SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc ID IMPACT AB Ultra high molecular weight polyethylene (UHMWPE) composite laminates were evaluated in ballistic testing to understand the effect of material architecture on the mechanisms involved in the transmission of stress waves during non-penetrating ballistic events. Little insight exists in the understanding of physiological effects of non-penetrating ballistic events, and the role ballistic materials and architecture play on the mitigation of stress transmission after impact. Previous ARL work has led to developmental architectures, including ARL X Hybrid, which exhibit improved resistance to back face deformation at no cost to ballistic resistance. The X Hybrid configuration was evaluated against the standard [0 degrees/90 degrees] composite layup to determine whether the architecture exhibited improved mitigation of stress wave transmission. Panels were tested and characterized using ARL's Behind Armor Blunt Trauma testing configuration to elucidate the mechanistic effects in both configurations. C1 [Vargas-Gonzalez, Lionel R.] US Army Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. [Gurganus, James C.] US Army Res Lab, Survivabil Lethal Anal Directorate, Aberdeen Proving Ground, MD 21005 USA. RP Vargas-Gonzalez, LR (reprint author), US Army Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. OI Vargas-Gonzalez, Lionel/0000-0001-6500-1686 NR 12 TC 1 Z9 1 U1 1 U2 5 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 1652 EP 1662 PG 11 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700179 ER PT J AU Rafaels, KA Gillich, PJ Moholkar, NM AF Rafaels, Karin A. Gillich, Patrick J. Moholkar, Nitin M. BE Ames, RG Boeka, RD TI INSIGHTS INTO EVALUATION TOOLS FOR ASSESSING THORACIC BEHIND-ARMOR BLUNT TRAUMA TEST DEVICES SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB Body armor that is designed to prevent bullets from perforating may cause injury due to the resulting backface deformation of the armor. However, behind-armor blunt trauma criteria and subsequent injury evaluations are known throughout the testing and evaluation community to have major limitations. This study assessed three evaluation tools fabricated to address some of the limitations: an anthropometric tool equipped with accelerometers and force sensors, a cylindrical response element with a laser displacement measurement device, and a hemi-cylindrical response element using digital image correlation. Although none of the evaluation tools were able to repeatedly and reliably measure the dynamic impact event, the tests allowed for the identification of key design considerations and methodology improvements for future devices. Material and instrumentation limitations were the greatest contributors to poor performance. As research continues to advance understanding in characterizing surrogate materials and improve instrumentation capabilities, a successful evaluation tool may soon be realized. C1 [Rafaels, Karin A.; Gillich, Patrick J.] Army Res Lab, Survivabil & Lethal Anal Directorate, Aberdeen Proving Ground, MD 21005 USA. [Moholkar, Nitin M.] Altus Engn LLC, Aberdeen Proving Ground, MD 21005 USA. RP Rafaels, KA (reprint author), Army Res Lab, Survivabil & Lethal Anal Directorate, 4502 Darlington Rd, Aberdeen Proving Ground, MD 21005 USA. NR 10 TC 0 Z9 0 U1 1 U2 2 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 1677 EP 1688 PG 12 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700182 ER PT J AU Kulaga, A Myers, T Gillich, P AF Kulaga, Autumn Myers, Timothy Gillich, Patrick BE Ames, RG Boeka, RD TI DESIGN UPGRADE TO THE PLYWOOD-PENETRATION MANNEQUIN SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc AB A standard plywood mannequin has been used for several decades by the military for evaluating personnel vulnerability to fragmenting munitions. It is used in both the context of lethality and survivability. The plywood mannequin was designed prior to the first ANSUR anthropometric survey and though it was designed to have a median stature relevant to the enemy combatant, the rest of its dimensions appear to be chosen arbitrarily. It has occasionally been criticized for the unusual dimensions in the upper extremities. Here, we propose a method for evaluating the plywood mannequin within the anthropometric space of the U.S. Army population. Using data collected from updated anthropometric studies and computer-assisted design, a population of new mannequins was created based on the current design of the plywood mannequin. This paper examines the currently used de facto standard and compares its vulnerability to that of a set of newly proposed plywood mannequins. C1 [Kulaga, Autumn; Myers, Timothy; Gillich, Patrick] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Kulaga, A (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. NR 7 TC 0 Z9 0 U1 0 U2 2 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 1722 EP 1732 PG 11 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700186 ER PT J AU Eberius, NL Hall, L VanAmburg, RL AF Eberius, Natalie L. Hall, Latrice VanAmburg, Rebecca L. BE Ames, RG Boeka, RD TI QUANTIFYING THE PROTECTIVE CAPABILITY OF BODY ARMOR USING M&S SO 28TH INTERNATIONAL SYMPOSIUM ON BALLISTICS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 28th International Symposium on Ballistics CY SEP 22-26, 2014 CL Atlanta, GA SP Natl Defense Ind Assoc, Int Ballist Soc ID FUNCTIONAL-CAPACITY INDEX AB Personnel protective equipment (PPE) is a primary element in the line of defense against fragmenting threats and is consequently a high-visibility subject area for the U.S. military. The Army Research Laboratory, Survivability/Lethality Analysis Directorate (ARL/SLAD) performs analyses to quantify the benefit of protecting the body from ballistic threats. ARL/SLAD developed an approach to holistically combine the characterization of the ballistic fragment threat with its effect on human injury, basic human functionality and their ultimate effect on military performance on the battlefield. Using the outcome metrics of injury, functional capability, and human performance from the Operational Requirement-based Casualty Assessment (ORCA) personnel model allows us to quantify armor benefit for various operational scenarios and military requirements. C1 [Eberius, Natalie L.; Hall, Latrice; VanAmburg, Rebecca L.] US Army Res Lab, RDRL SLB W, Aberdeen Proving Ground, MD 21005 USA. RP Eberius, NL (reprint author), US Army Res Lab, RDRL SLB W, Aberdeen Proving Ground, MD 21005 USA. NR 5 TC 0 Z9 0 U1 0 U2 2 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-149-2 PY 2014 BP 1766 EP 1773 PG 8 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BC2IL UT WOS:000350969700190 ER PT S AU Richie, D Ross, J Ruloff, J Park, S Pollock, L Shires, D AF Richie, David Ross, James Ruloff, Jordan Park, Song Pollock, Lori Shires, Dale BE Mey, DA Alexander, M Bientinesi, P Cannataro, M Clauss, C Costan, A Kecskemet, G Morin, C Ricci, L Sahuquillo, J Schulz, M Scarano, V Scott, SL Weidendorfer, J TI Investigation of Parallel Programmability and Performance of a Calxeda ARM Server Using OpenCL SO EURO-PAR 2013: PARALLEL PROCESSING WORKSHOPS SE Lecture Notes in Computer Science LA English DT Proceedings Paper CT 19th Workshop on Parallel Processing (Euro-Par) CY AUG 26-27, 2013 CL Aachen, GERMANY DE High Performance Computing; ARM server; OpenCL AB This paper explores the parallel programmability, performance, and energy efficiency of a recently available Calxeda ARM-based server as a potential energy-efficient platform for computationally intensive applications. A novel OpenCL-based parallel programming model for the Calxeda ARM server is achieved via the use of a higher level STandarD Compute Layer (STDCL) application programming interface and a remote procedure call (RPC) implementation. Empirical measurements of the performance of the platform are obtained and presented using an N-body code executed in various configurations. Furthermore, an auto-tuning technique was developed and analyzed for optimization of the N-body algorithm on a specific architecture. C1 [Richie, David] Brown Deer Technol, Forest Hill, MD 21050 USA. [Ross, James; Ruloff, Jordan] DRC, Andover, MA USA. [Park, Song; Shires, Dale] US Army, Res Lab, Aberdeen, MD USA. [Pollock, Lori] Univ Delaware, Newark, DE USA. RP Richie, D (reprint author), Brown Deer Technol, Forest Hill, MD 21050 USA. EM drichie@browndeertechnology.com; jaross@drc.com; jruloff@drc.com; song.j.park.civ@mail.mil; pollock@udel.edu; dale.r.shires.civ@mail.mil NR 14 TC 0 Z9 0 U1 0 U2 3 PU SPRINGER-VERLAG BERLIN PI BERLIN PA HEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY SN 0302-9743 BN 978-3-642-54419-4; 978-3-642-54420-0 J9 LECT NOTES COMPUT SC PY 2014 VL 8374 BP 865 EP 874 PG 10 WC Computer Science, Theory & Methods SC Computer Science GA BC2FI UT WOS:000350859500097 ER PT B AU Mudryy, R Jia, S Nastac, L AF Mudryy, Ruslan Jia, Shian Nastac, Laurentiu BE Tiryakioglu, M Campbell, J Byczynski, G TI Recent Advances on the Solidification Processing of Cast Energetic Materials SO SHAPE CASTING LA English DT Proceedings Paper CT 5th Shape Casting Symposium held at the Minerals, Metals & Materials Society Annual Meeting & Exhibition CY FEB 16-20, 2014 CL San Diego, CA SP Aluminum Comm Light Metals Div, Minerals, Metals & Mat Soc, Mat Proc & Mfg Div, Solidificat Comm AB This paper investigates the solidification of highly viscous energetic materials cast into a projectile. Active cooling and heating (ACH) control solidification technology as well as mechanical vibration (MV) are applied to achieve unidirectional solidification and to reduce cracks, gas pores, and shrinkage defects and to decrease the detrimental gap size between the projectile and the solidified energetic material. A comprehensive numerical model was developed to simulate the solidification processes during casting of energetic materials, as well as the resulting induced thermal stresses. The optimized design parameters of the proposed technologies are developed based on numerical modeling and experiment work. A detailed comparison between the latest experiments performed at the University of Alabama, Solidification Laboratory, obtained with electrical heating and water cooling and with and without mechanical vibration is provided in this paper. In these experiments, a special wax material (e.g., Chlorez 700S) that has similar thermo-physical properties with the IMX-104 explosive material was used. Experiments performed at the USARMY ARDEC using the IMX-104 explosive material with steam heating and water cooling are also presented in this paper. These experiments are being used to further validate the numerical model. C1 [Mudryy, Ruslan] US Army, RDECOM ARDEC, Armaments Engn & Technol Ctr, Picatilmy, NJ 07806 USA. [Jia, Shian; Nastac, Laurentiu] Univ Alabama, Dept Met & Mat Engn, Tuscaloosa, AL 35487 USA. RP Mudryy, R (reprint author), US Army, RDECOM ARDEC, Armaments Engn & Technol Ctr, Picatilmy, NJ 07806 USA. EM ruslan.s.mudryy@us.army.mil; lnastac@eng.ua.edu NR 12 TC 0 Z9 0 U1 0 U2 3 PU JOHN WILEY & SONS INC PI HOBOKEN PA 111 RIVER ST, HOBOKEN, NJ 07030 USA BN 978-1-118-88809-4; 978-1-118-88818-6 PY 2014 BP 67 EP 74 PG 8 WC Engineering, Mechanical; Metallurgy & Metallurgical Engineering SC Engineering; Metallurgy & Metallurgical Engineering GA BC2IH UT WOS:000350964300009 ER PT J AU Mejias-Santiago, M Doyle, JD Rushing, JF AF Mejias-Santiago, Mariely Doyle, Jesse D. Rushing, John F. TI Accelerated Pavement Testing of Warm-Mix Asphalt for Heavy-Traffic Airfields SO TRANSPORTATION RESEARCH RECORD LA English DT Article AB The results from accelerated pavement testing on warm-mix asphalt (WMA) mixtures designed for airfield pavements are presented. Three WMA mixtures and one hot-mix asphalt (HMA) mixture produced in an asphalt plant were evaluated under simulated heavy aircraft traffic. The evaluation was conducted at extreme traffic conditions, including heavy aircraft loading, high tire pressure, and high pavement temperature. Pavement structural response and rutting were evaluated to assess the susceptibility to permanent deformation of WMA mixtures compared with that of HMA produced with the same aggregate blend. Test results indicated that WMA was a viable product for surface mixtures on airfield pavements. C1 [Mejias-Santiago, Mariely; Doyle, Jesse D.; Rushing, John F.] US Army, Geotech & Struct Lab, Airfields & Pavements Branch, Engn Res & Dev Ctr,CEERD GM A, Vicksburg, MS 39180 USA. RP Mejias-Santiago, M (reprint author), US Army, Geotech & Struct Lab, Airfields & Pavements Branch, Engn Res & Dev Ctr,CEERD GM A, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM mariely.mejias@erdc.dren.mil FU U.S. Air Force Civil Engineering Center FX This research was funded by the U.S. Air Force Civil Engineering Center. The authors thank Quint Mason, Tommy Carr, and Tony Brogdon for their assistance with the test section construction, data collection, and sampling during full-scale production. Permission to publish was granted by the director of the Geotechnical and Structures Laboratory, U.S. Army Engineer Research and Development Center. NR 15 TC 1 Z9 1 U1 2 U2 6 PU NATL ACAD SCIENCES PI WASHINGTON PA 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA SN 0361-1981 EI 2169-4052 J9 TRANSPORT RES REC JI Transp. Res. Record PY 2014 IS 2456 BP 11 EP 20 DI 10.3141/2456-02 PG 10 WC Engineering, Civil; Transportation; Transportation Science & Technology SC Engineering; Transportation GA CD4BB UT WOS:000351026500003 ER PT J AU Priddy, LP Pittman, DW Flintsch, GW AF Priddy, Lucy P. Pittman, David W. Flintsch, Gerardo W. TI Load Transfer Characteristics of Precast Portland Cement Concrete Panels for Airfield Pavement Repairs SO TRANSPORTATION RESEARCH RECORD LA English DT Article AB Portland cement concrete pavement repair technologies using precast portland cement concrete panels have been investigated for decades and recently have gained acceptance and increased use in the United States for highway pavements but have had only limited use for airfields. The recent field testing of a new airfield precast panel repair system indicated that precast panels were suitable for expedient airfield pavement repairs; the panels could withstand between 5,000 and 10,000 passes of C-17 aircraft traffic. Failure of the panels was due to spalling of the transverse doweled joints. The purpose of this study was to determine the load transfer effectiveness, or load transfer efficiencies (LTEs), of the panel repairs. A heavy weight deflectometer was used to collect deflection data before, during, and after trafficking to calculate precast panel LTE on the basis of deflections (LTE delta) or transferred stresses (LT). The LTE values were then evaluated to determine whether current measures of effectiveness were suitable for precast panel repairs. From the results of this investigation, few of the joints provided the current military airfield design assumption of 25% LT, but the majority of the transverse joints exceeded the proposed LTE delta threshold of 70% even after failure of the transverse joints. It was recommended that additional field tests be conducted without the use of rapid-setting grout in the joints before recommendations on thresholds were made. C1 [Priddy, Lucy P.; Pittman, David W.] US Army, Engn Res & Dev Ctr, CEERD GM A, Vicksburg, MS 39180 USA. [Flintsch, Gerardo W.] Virginia Polytech Inst & State Univ, Dept Civil & Environm Engn, Blacksburg, VA 24061 USA. RP Priddy, LP (reprint author), US Army, Engn Res & Dev Ctr, CEERD GM A, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM lucy.p.priddy@usace.army.mil FU U.S. Air Force Civil Engineer Center FX Information described and presented here, unless otherwise noted, was obtained from research sponsored by the U.S. Air Force Civil Engineer Center and performed at the U.S. Army Engineer Research and Development Center. Permission to publish this information was granted by the director of the Geotechnical and Structures Laboratory. NR 22 TC 0 Z9 0 U1 1 U2 2 PU NATL ACAD SCIENCES PI WASHINGTON PA 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA SN 0361-1981 EI 2169-4052 J9 TRANSPORT RES REC JI Transp. Res. Record PY 2014 IS 2456 BP 42 EP 53 DI 10.3141/2456-05 PG 12 WC Engineering, Civil; Transportation; Transportation Science & Technology SC Engineering; Transportation GA CD4BB UT WOS:000351026500006 ER PT S AU Shoop, BL AF Shoop, Barry L. BE Costa, MFPCM Zghal, M TI Developing Critical Thinking, Creativity and Innovation Skills of Undergraduate Students SO 12TH EDUCATION AND TRAINING IN OPTICS AND PHOTONICS CONFERENCE SE Proceedings of SPIE LA English DT Proceedings Paper CT 12th Education and Training in Optics and Photonics Conference CY JUL 23-26, 2013 CL Porto, PORTUGAL SP Int Commiss Opt, IEEE Photon Soc, Opt Soc, SPIE DE Critical thinking skills; creativity; innovation; disruptive technology AB A desirable goal of engineering education is to teach students how to be creative and innovative. However, the speed of technological innovation and the continual expansion of disciplinary knowledge leave little time in the curriculum for students to formally study innovation. At West Point we have developed a novel upper-division undergraduate course that develops the critical thinking, creativity and innovation of undergraduate science and engineering students. This course is structured as a deliberate interactive engagement between students and faculty that employs the Socratic method to develop an understanding of disruptive and innovative technologies and a historical context of how social, cultural, and religious factors impact the acceptance or rejection of technological innovation. The course begins by developing the background understanding of what disruptive technology is and a historical context about successes and failures of social, cultural, and religious acceptance of technological innovation. To develop this framework, students read The Innovator's Dilemma by Clayton M. Christensen, The Structure of Scientific Revolutions by Thomas S. Kuhn, The Discoverers by Daniel J. Boorstin, and The Two Cultures by C.P. Snow. For each class meeting, students survey current scientific and technical literature and come prepared to discuss current events related to technological innovation. Each student researches potential disruptive technologies and prepares a compelling argument of why the specific technologies are disruptive so they can defend their choice and rationale. During course meetings students discuss the readings and specific technologies found during their independent research. As part of this research, each student has the opportunity to interview forward thinking technology leaders in their respective fields of interest. In this paper we will describe the course and highlight the results from teaching this course over the past five years. C1 US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. RP Shoop, BL (reprint author), US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. EM Barry.Shoop@usma.edu NR 18 TC 0 Z9 0 U1 2 U2 7 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-364-9 J9 PROC SPIE PY 2014 VL 9289 AR 928904 DI 10.1117/12.2068495 PG 7 WC Optics SC Optics GA BC1PD UT WOS:000350340900003 ER PT B AU Boose, DW Matray, JI AF Boose, Donald W., Jr. Matray, James I. BE Matray, JI Boose, DW TI The Ashgate Research Companion to the Korean War Introduction SO ASHGATE RESEARCH COMPANION TO THE KOREAN WAR LA English DT Editorial Material; Book Chapter C1 [Boose, Donald W., Jr.] US Army War Coll, Carlisle, PA 17013 USA. [Matray, James I.] Calif State Univ Chico, Chico, CA 95929 USA. RP Boose, DW (reprint author), US Army War Coll, Carlisle, PA 17013 USA. NR 21 TC 1 Z9 1 U1 0 U2 0 PU ASHGATE PUBLISHING LTD PI ALDERSHOT PA GOWER HOUSE, CROFT ROAD, ALDERSHOT GU11 3HR, ENGLAND BN 978-1-4094-3929-5; 978-1-4094-3928-8 PY 2014 BP 1 EP 5 PG 5 WC History; Political Science SC History; Government & Law GA BB9YM UT WOS:000348804700001 ER PT B AU Shrader, CR AF Shrader, Charles R. BE Matray, JI Boose, DW TI Logistics SO ASHGATE RESEARCH COMPANION TO THE KOREAN WAR LA English DT Article; Book Chapter C1 [Shrader, Charles R.] US Army, Washington, DC USA. NR 136 TC 0 Z9 0 U1 0 U2 0 PU ASHGATE PUBLISHING LTD PI ALDERSHOT PA GOWER HOUSE, CROFT ROAD, ALDERSHOT GU11 3HR, ENGLAND BN 978-1-4094-3929-5; 978-1-4094-3928-8 PY 2014 BP 163 EP 175 PG 13 WC History; Political Science SC History; Government & Law GA BB9YM UT WOS:000348804700013 ER PT B AU Crane, CC AF Crane, Conrad C. BE Matray, JI Boose, DW TI Atomic, Chemical, and Biological Weapons SO ASHGATE RESEARCH COMPANION TO THE KOREAN WAR LA English DT Article; Book Chapter ID KOREAN-WAR; WARFARE C1 [Crane, Conrad C.] US Army Mil Hist Inst, Carlisle, PA USA. RP Crane, CC (reprint author), US Army War Coll, US Army Heritage & Educ Ctr, Carlisle, PA 17013 USA. NR 50 TC 0 Z9 0 U1 2 U2 5 PU ASHGATE PUBLISHING LTD PI ALDERSHOT PA GOWER HOUSE, CROFT ROAD, ALDERSHOT GU11 3HR, ENGLAND BN 978-1-4094-3929-5; 978-1-4094-3928-8 PY 2014 BP 177 EP 184 PG 8 WC History; Political Science SC History; Government & Law GA BB9YM UT WOS:000348804700014 ER PT B AU Boose, DW AF Boose, Donald W., Jr. BE Matray, JI Boose, DW TI Amphibious Warfare SO ASHGATE RESEARCH COMPANION TO THE KOREAN WAR LA English DT Article; Book Chapter C1 US Army War Coll, Carlisle, PA 17013 USA. RP Boose, DW (reprint author), US Army War Coll, Carlisle, PA 17013 USA. NR 88 TC 0 Z9 0 U1 0 U2 0 PU ASHGATE PUBLISHING LTD PI ALDERSHOT PA GOWER HOUSE, CROFT ROAD, ALDERSHOT GU11 3HR, ENGLAND BN 978-1-4094-3929-5; 978-1-4094-3928-8 PY 2014 BP 185 EP 198 PG 14 WC History; Political Science SC History; Government & Law GA BB9YM UT WOS:000348804700015 ER PT B AU Gray, D AF Gray, David BE Matray, JI Boose, DW TI Special Operations SO ASHGATE RESEARCH COMPANION TO THE KOREAN WAR LA English DT Article; Book Chapter C1 [Gray, David] US Mil Acad, West Point, NY USA. [Gray, David] Univ Maryland, College Pk, MD USA. [Gray, David] Valley Forge Mil Acad & Coll, Wayne, PA USA. RP Gray, D (reprint author), Ohio State Univ, Columbus, OH 43210 USA. NR 72 TC 0 Z9 0 U1 0 U2 0 PU ASHGATE PUBLISHING LTD PI ALDERSHOT PA GOWER HOUSE, CROFT ROAD, ALDERSHOT GU11 3HR, ENGLAND BN 978-1-4094-3929-5; 978-1-4094-3928-8 PY 2014 BP 213 EP 226 PG 14 WC History; Political Science SC History; Government & Law GA BB9YM UT WOS:000348804700017 ER PT B AU Latham, WC AF Latham, William C., Jr. BE Matray, JI Boose, DW TI Kaesong and P'anmunjom SO ASHGATE RESEARCH COMPANION TO THE KOREAN WAR LA English DT Article; Book Chapter ID KOREAN-WAR; NEGOTIATIONS C1 US Army Logist Univ, Operat Contract Support Course, Ft Lee, VA 23801 USA. RP Latham, WC (reprint author), US Army Logist Univ, Operat Contract Support Course, Ft Lee, VA 23801 USA. NR 71 TC 0 Z9 0 U1 0 U2 0 PU ASHGATE PUBLISHING LTD PI ALDERSHOT PA GOWER HOUSE, CROFT ROAD, ALDERSHOT GU11 3HR, ENGLAND BN 978-1-4094-3929-5; 978-1-4094-3928-8 PY 2014 BP 395 EP 406 PG 12 WC History; Political Science SC History; Government & Law GA BB9YM UT WOS:000348804700031 ER PT B AU Boose, DW AF Boose, Donald W., Jr. BE Matray, JI Boose, DW TI Order of Battle SO ASHGATE RESEARCH COMPANION TO THE KOREAN WAR LA English DT Article; Book Chapter C1 US Army War Coll, Carlisle, PA 17013 USA. RP Boose, DW (reprint author), US Army War Coll, Carlisle, PA 17013 USA. NR 40 TC 0 Z9 0 U1 0 U2 0 PU ASHGATE PUBLISHING LTD PI ALDERSHOT PA GOWER HOUSE, CROFT ROAD, ALDERSHOT GU11 3HR, ENGLAND BN 978-1-4094-3929-5; 978-1-4094-3928-8 PY 2014 BP 435 EP 461 PG 27 WC History; Political Science SC History; Government & Law GA BB9YM UT WOS:000348804700034 ER PT S AU Wu, GF Turcotte, DE Dwornick, BL Dusenbury, JS Turcotte, KL Cheng, XR Yang, Y Lockwood, FE AF Wu, Gefei Turcotte, David E. Dwornick, Bridget L. Dusenbury, James S. Turcotte, Kelsey L. Cheng, Xiurong Yang, Ying Lockwood, Frances E. BE Eaton, ER TI Integration of Nano-Fluids into Commercial Antifreeze Concentrates With ASTM D15 Corrosion Testing SO GLOBAL TESTING OF EXTENDED SERVICE ENGINE COOLANTS AND RELATED FLUIDS SE American Society for Testing and Materials Special Technical Publications LA English DT Proceedings Paper CT Symposium on Global Testing of Extended Service Engine Coolants and Related Fluids CY MAY 23, 2013 CL Indianapolis, IN SP ASTM Int Comm D15 Engine Coolants & Related Fluids, ASTM Subcommittee D15.21 Extended Life Coolants DE graphite; alumina; nano-fluids; thermal conductivity; ASTM D15 corrosion tests ID THERMAL-CONDUCTIVITY; NANOFLUIDS AB Originally, five candidates of nano-material were chosen for making stable nano-dispersions. Nano-graphite particles remain a practical choice for nano-fluids thermal application after taking divergent performance attributes into full account: significant thermal conductivity increases, minimal viscosity increase, low density for better dispersion stability, and relatively low cost, among others. Three different types of commercial antifreeze coolants were chosen for the integration with graphite nano-fluids. Without corrosion inhibitors, our nano-coolants typically fail both ASTM D15 engine coolant corrosion tests. Yet, heating up and adding in electrolytes are two common ways to destroy a nano-particle dispersion. After making adjustments in particle loading, choosing an effective dispersant, and establishing proper dispersant levels, one nano-graphite coolant made from commercial nano-source passed both engine coolant corrosion tests plus the CID AA-52624A compatibility and storage stability tests. Compared with the base fluid, the nano-graphite coolant's thermal conductivity has more than a 25 % increase at 2 vol. % particle loading, which is a significant enhancement. C1 [Wu, Gefei; Turcotte, David E.; Turcotte, Kelsey L.; Cheng, Xiurong; Yang, Ying; Lockwood, Frances E.] Ashland Consumer Markets, Valvoline New Prod Dev Lab, Lexington, KY 40509 USA. [Dwornick, Bridget L.; Dusenbury, James S.] US Army, Ctr Dev & Engn, Tank Automot Res, Warren, MI 48092 USA. RP Wu, GF (reprint author), Ashland Consumer Markets, Valvoline New Prod Dev Lab, Lexington, KY 40509 USA. EM gwu@ashland.com NR 14 TC 0 Z9 0 U1 1 U2 4 PU ASTM INTERNATIONAL PI WEST CONSHOHOCKEN PA 100 BARR HARBOR DRIVE, PO BOX C700, WEST CONSHOHOCKEN, PA 19428-2959 USA SN 0066-0558 BN 978-0-8031-7542-6 J9 AM SOC TEST MATER PY 2014 VL 1556 BP 57 EP 70 DI 10.1520/STP155620130073 PG 14 WC Materials Science, Multidisciplinary; Materials Science, Characterization & Testing SC Materials Science GA BC2OJ UT WOS:000351133300004 ER PT S AU Durst, PJ Gray, W Nikitenko, A Caetano, J Trentini, M King, R AF Durst, Phillip J. Gray, Wendell Nikitenko, Agris Caetano, Joao Trentini, Michael King, Roger GP IEEE TI A Framework for Predicting the Mission-Specific Performance of Autonomous Unmanned Systems SO 2014 IEEE/RSJ INTERNATIONAL CONFERENCE ON INTELLIGENT ROBOTS AND SYSTEMS (IROS 2014) SE IEEE International Conference on Intelligent Robots and Systems LA English DT Proceedings Paper CT IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) CY SEP 14-18, 2014 CL Chicago, IL SP IEEE, Robot Soc Japan, RA, SICE, IES, New Technol Fdn AB While many methodologies have been proposed for calculating a quantitative level of autonomy for intelligent Unmanned Systems (UMS), no one definitive measure of autonomy or autonomous performance has been validated and adopted by the UMS community. Particularly for military applications, a simple performance metric that is based on the UMSs mission profile and is comparable between UMS systems is critical. This metric would not only help define the features a UMS needs to successfully perform its mission, both in terms of hardware and software, but also enable the use of UMS for a broader range of applications at an increased level of autonomy. This paper presents the development of a new methodology for calculating a single-number performance metric for autonomous UMS, and this metric is called the Mission Performance Potential (MPP). Rather than a retroactive measure of UMS performance and autonomy level for one iteration of a given scenario, the MPP separates autonomy level and mission performance to provide a predictive measure of a UMS's expected performance for a mission set and level of autonomy. As an example application, the MPP is calculated for an Unmanned Aerial Vehicle (UAV) performing a target tracking mission, and this MPP value is compared to the results of field-testing with this system. C1 [Durst, Phillip J.; Gray, Wendell] US Army Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. RP Durst, PJ (reprint author), US Army Engineer Res & Dev Ctr, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM phillip.j.durst@erdc.dren.mil; agris@cs.rtu.lv; jvcaetano@academiafa.edu; mike.drdc@shaw.ca; rking@cavs.msstate.edu NR 14 TC 1 Z9 1 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2153-0858 BN 978-1-4799-6934-0 J9 IEEE INT C INT ROBOT PY 2014 BP 1962 EP 1969 PG 8 WC Computer Science, Artificial Intelligence; Engineering, Electrical & Electronic; Robotics SC Computer Science; Engineering; Robotics GA BC0YL UT WOS:000349834602012 ER PT S AU Fink, JR Stump, EA AF Fink, Jonathan R. Stump, Ethan A. GP IEEE TI Experimental Analysis of Models for Trajectory Generation on Tracked Vehicles SO 2014 IEEE/RSJ INTERNATIONAL CONFERENCE ON INTELLIGENT ROBOTS AND SYSTEMS (IROS 2014) SE IEEE International Conference on Intelligent Robots and Systems LA English DT Proceedings Paper CT IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) CY SEP 14-18, 2014 CL Chicago, IL SP IEEE, Robot Soc Japan, RA, SICE, IES, New Technol Fdn ID WHEELED MOBILE ROBOTS AB We begin to bridge the gap between high-level motion planning and execution by adopting models to abstract the complicated skid-steer vehicle dynamics and evaluating their suitability as motion predictors for a feed-forward control framework. We consider three kinematic motion models and a drivetrain model in experiments on two surface types with a small tracked vehicle. We perform statistical analysis of the predictive accuracy of these models when used to create optimal open-loop plans for a set of canonical maneuvers and discuss the applicability of these models for a closed-loop control framework. C1 [Fink, Jonathan R.; Stump, Ethan A.] United States Army, Res Lab, Adelphi, MD 20783 USA. RP Fink, JR (reprint author), United States Army, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM jonathan.r.fink3.civ@mail.mil; ethan.a.stump.civ@mail.mil NR 19 TC 3 Z9 3 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2153-0858 BN 978-1-4799-6934-0 J9 IEEE INT C INT ROBOT PY 2014 BP 1970 EP 1977 PG 8 WC Computer Science, Artificial Intelligence; Engineering, Electrical & Electronic; Robotics SC Computer Science; Engineering; Robotics GA BC0YL UT WOS:000349834602013 ER PT S AU Kessens, CC Lennon, CT Collins, J AF Kessens, Chad C. Lennon, Craig T. Collins, Jason GP IEEE TI A Metric for Self-Rightability and Understanding Its Relationship to Simple Morphologies SO 2014 IEEE/RSJ INTERNATIONAL CONFERENCE ON INTELLIGENT ROBOTS AND SYSTEMS (IROS 2014) SE IEEE International Conference on Intelligent Robots and Systems LA English DT Proceedings Paper CT IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) CY SEP 14-18, 2014 CL Chicago, IL SP IEEE, Robot Soc Japan, RA, SICE, IES, New Technol Fdn ID ROBOT AB To robustly operate in dynamic, unknown environments, robots should be able to autonomously recover from simple errors such as tip-over. Most efforts to date have introduced specific techniques applied as point solutions on simple terrain. For a more general solution, we previously introduced a framework for analyzing and generating solutions to the self-righting problem for a generic robot. In this paper, we turn our attention toward understanding how a robot's morphology affects its ability to self-right. We begin by briefly reviewing our framework, which is used to generate the results within the paper. We then introduce a self-rightability metric that can be used to evaluate a given robot design's potential for self-righting. It can also be used to compare disparate designs. Next, we show how the metric can be used to perform a parametric study covering multiple design variables for a simple robot class. In this way, we hope to enable designers to begin to understand how design parameters such as joint limits, limb length, limb to body mass ratio, limb mass location, and body aspect ratio will affect the robot's ability to self-right on a variety of ground angles. Finally, we show a case study of limb mass and validate results using a modular, 3 degree of freedom physical robot. Ultimately, we hope to enable the production of robots that are more capable of autonomously self-righting. C1 [Kessens, Chad C.; Lennon, Craig T.] US Army, Res Lab ARL, Aberdeen Proving Ground, MD 21005 USA. RP Kessens, CC (reprint author), US Army, Res Lab ARL, Aberdeen Proving Ground, MD 21005 USA. NR 21 TC 1 Z9 1 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2153-0858 BN 978-1-4799-6934-0 J9 IEEE INT C INT ROBOT PY 2014 BP 3699 EP 3704 PG 6 WC Computer Science, Artificial Intelligence; Engineering, Electrical & Electronic; Robotics SC Computer Science; Engineering; Robotics GA BC0YL UT WOS:000349834603121 ER PT B AU Rushing, JF Doyle, JD Harrison, A AF Rushing, John F. Doyle, Jesse D. Harrison, Andrew BE Kim, YR TI Significance of non-load related distresses on airfield asphalt pavements: Review of 25 years of pavement management data SO ASPHALT PAVEMENTS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 12th ISAP International Conference on Asphalt Pavements CY JUN 01-05, 2014 CL Raleigh, NC SP ISAP, Carolina Asphalt Pavement Assoc, TROXLER, Korea Inst Construct Technol, InstroTek Inc, Natl Asphalt Pavement Assoc, Dongre Lab Serv Inc, Heritage Grp AB Non-load related distresses are a major factor contributing to the need for maintenance and rehabilitation of Hot-Mix Asphalt (HMA) airfield pavements. By using pavement management system data, the quantity of these non-load related distresses can be determined. This paper summarizes data gleaned from the analysis of over 8 million square meters of HMA airfield pavement to identify the most significant types of surface distresses according to the Pavement Condition Index (PCI). These data represent 25 years of using the pavement management system, Micro PAVER, to determine the condition of U. S. Army airfield pavements. The quantity of longitudinal and transverse cracking, raveling and weathering, and block cracking was extracted from the database for various ages of pavements. In addition, the total percentage of non-load related distresses was identified for various ages of pavements. Findings from this analysis of existing data highlight the need for improved maintenance procedures to combat the need for maintenance and rehabilitation related to non-load distresses in HMA. The benefits of preventive maintenance are discussed, along with the need to monitor the application of various approaches using techniques employed by pavement management systems. C1 [Rushing, John F.; Doyle, Jesse D.; Harrison, Andrew] US Army, Engn Res & Dev Ctr, Vicksburg, MS 39180 USA. RP Rushing, JF (reprint author), US Army, Engn Res & Dev Ctr, Vicksburg, MS 39180 USA. NR 5 TC 0 Z9 0 U1 1 U2 2 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-315-73675-4; 978-1-138-02693-3 PY 2014 BP 253 EP 261 PG 9 WC Construction & Building Technology; Engineering, Environmental; Engineering, Civil SC Construction & Building Technology; Engineering GA BB8SH UT WOS:000347408100025 ER PT B AU Murugan, M Yoo, J Hiemenz, G Wereley, N AF Murugan, Muthuvel Yoo, JinHyeong Hiemenz, Gregory Wereley, Norman GP ASME TI ANALYTICAL EVALUATION OF ADAPTIVE SEAT ENERGY ABSORBER FOR ROTORCRAFT SEMI-ACTIVE CRASH SAFETY SEAT DEVELOPMENT SO PROCEEDINGS OF THE ASME CONFERENCE ON SMART MATERIALS, ADAPTIVE STRUCTURES, AND INTELLIGENT SYSTEMS - 2013, VOL 1 LA English DT Proceedings Paper CT ASME Conference on Smart Materials, Adaptive Structures and Intelligent Systems CY SEP 16-18, 2013 CL Snowbird, UT SP ASME, Aerospace Div, Gen Motors, Dynalloy Inc, Parker Hannifin, Teledyne Sci & Imag, IOP Publish, Sage Publish, NextGen Aeronaut, Natl Sci Fdn, Boeing, GE Global Res AB This research study focuses on the analytical evaluation of magneto-rheological (MR) dampers for enhanced occupant protection during vertical crash landings of a helicopter. The current state-of-the-art helicopter crew seat has passive safety mechanisms that are highly limited in their capability to optimally adapt to each type of crash scenario due to variations in both occupant weight and crash severity level. While passive crash energy absorbers work well for a single design condition (50111 percentile male occupant and fixed crash severity leve,1), they do not offer adequate protection across a broad spectrum of crash conditions by minimizing the load transmitted to the occupant. This study reports the development of a lumped-parameter human body model including lower leg in a seated posture for rotorcraft crash injury simulation. A physical model of lumped-parameter human body restrained on a crew seat was implemented in multi-body dynamics simulation software. For implementing control, a control algorithm was made to work with the multi-body dynamic model by running co-simulation. The injury criteria and tolerance levels for the biomechanical effects are discussed for each of the identified vulnerable body regions, such as the thoracic lumbar loads for different sized adults. The desired objective of this analytical model development is to develop a tool to study the performance of adaptive semi-active magnetorheological seat suspensions for rotorcraft occupant protection. C1 [Murugan, Muthuvel; Yoo, JinHyeong] US Army, Res Lab, Vehicle Technol Directorate, Aberdeen Proving Ground, MD 21005 USA. [Hiemenz, Gregory] Techno Sci Inc, Beltsville, MD USA. [Wereley, Norman] Univ Maryland, College Pk, MD USA. RP Murugan, M (reprint author), US Army, Res Lab, Vehicle Technol Directorate, Aberdeen Proving Ground, MD 21005 USA. FU Joint Aircraft Survivability Program Office [JASP# V-13-02] FX This research effort is being performed under a research funding awarded by the Joint Aircraft Survivability Program Office (Project Number: JASP# V-13-02). NR 14 TC 0 Z9 0 U1 1 U2 3 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5603-1 PY 2014 AR UNSP V001T04A015 PG 8 WC Automation & Control Systems; Materials Science, Multidisciplinary SC Automation & Control Systems; Materials Science GA BC1BE UT WOS:000349927900092 ER PT B AU Raghunath, G Flatau, AB Purekar, A Yoo, JH AF Raghunath, Ganesh Flatau, Alison B. Purekar, Ashish Yoo, Jin-Hyeong GP ASME TI NON-CONTACT TORQUE MEASUREMENT USING MAGNETOSTRICTIVE GALFENOL SO PROCEEDINGS OF THE ASME CONFERENCE ON SMART MATERIALS, ADAPTIVE STRUCTURES, AND INTELLIGENT SYSTEMS - 2013, VOL 1 LA English DT Proceedings Paper CT ASME Conference on Smart Materials, Adaptive Structures and Intelligent Systems CY SEP 16-18, 2013 CL Snowbird, UT SP ASME, Aerospace Div, Gen Motors, Dynalloy Inc, Parker Hannifin, Teledyne Sci & Imag, IOP Publish, Sage Publish, NextGen Aeronaut, Natl Sci Fdn, Boeing, GE Global Res ID IRON-GALLIUM ALLOYS AB This work deals with the development of a non-contact torque sensor system prototype made from rolled and textured Galfenol, a magnetostrictive alloy of Iron and Gallium. It is already known that this smart material exhibits a linear response to strain in the presence of appropriate biasing magnets. The response of a sensor system built from it follows commercially available strain gages. In this research, the magnetic change in Galfenol due to shear strain experienced by the shaft in torque will be monitored using Hall effect sensors to derive the torque information. Factors affecting the performance of this Wireless Magneto-Elastic Torque Sensor System (WIMETs) such as annealing, rolling process and strain transfer of adhesives shall be explored. The ability to provide real-time measurements with minimal signal conditioning requirements make a well-designed torque system attractive for applications such as condition based maintenance. Factors such as being non-contact and passive to the shaft, compact and easy to install, accurate, sensitive and cost effective are highly desired for any torque measurement system. A rate-of-change torque sensor that demonstrates both a sensitivity and time resolution high enough to not only recognize failing machinery, but to specifically identify the failing part is also a critical feature. These characteristics have been incorporated in the current design of WIMETs. A mathematical model for the magneto-elastic coupling along with simulations from COMSOL shall be presented. Results from static tests for various torques and dynamic tests for various torques at different RPMs will be discussed. It will be shown that the WiMET sensor system setup in a clamshell is reliable and exhibits sensitivity of up to 10mV/in-lb. over a wide range of torque (0-150 lb.-in). Its performance will be compared with a commercial torque sensor and results for detection of eccentric loads on the shaft will also be furnished. C1 [Raghunath, Ganesh; Flatau, Alison B.] Univ Maryland, College Pk, MD 20742 USA. [Purekar, Ashish] Techno Sci Inc, Beltsville, MD USA. [Yoo, Jin-Hyeong] US Army Res Lab, Aberdeen Proving Ground, MD USA. RP Raghunath, G (reprint author), Univ Maryland, College Pk, MD 20742 USA. RI Lin, Zhao/C-8319-2011 OI Lin, Zhao/0000-0002-6131-9723 FU US Navy STTR [N00014-11-MO279] FX This project is sponsored under a US Navy STTR Contract #N00014-11-MO279 with Dr. H. Scott Coombe as program monitor. The author would also like to thank Dr. Suok-Min Na, University of Maryland for helping with manufacture of the materials and Dr. Jin-Hyeong Yoo, US Army Research Laboratory, Aberdeen for his valuable inputs during the course of this research. NR 14 TC 0 Z9 0 U1 1 U2 2 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5603-1 PY 2014 AR UNSP V001T04A013 PG 12 WC Automation & Control Systems; Materials Science, Multidisciplinary SC Automation & Control Systems; Materials Science GA BC1BE UT WOS:000349927900090 ER PT S AU Rezaei, MA Wang, GY Huang, AQ Cheng, L Palmour, JW Scozzie, C AF Rezaei, Mohammad Ali Wang, Gangyao Huang, Alex Q. Cheng, Lin Palmour, John W. Scozzie, Charles BE Okumura, H Harima, H Kimoto, T Yoshimoto, M Watanabe, H Hatayama, T Matsuura, H Funaki, T Sano, Y TI Static and Dynamic Performance Evaluation of > 13 kV SiC-ETO and Its Application as A Solid-State Circuit Breaker SO SILICON CARBIDE AND RELATED MATERIALS 2013, PTS 1 AND 2 SE Materials Science Forum LA English DT Proceedings Paper CT 15th International Conference on Silicon Carbide and Related Materials (ICSCRM) CY SEP 29-OCT 04, 2013 CL Miyazaki, JAPAN SP Japan Soc Appl Phys, Res Inst Appl Sci, Inst Elect, Informat & Commun Engineers, Inst Elect Engineers Japan, Ceram Soc Japan, Surface Sci Soc Japan, Japanese Asso Crystal Growth, Vacuum Soc Japan, MITSUBISHI ELECT CORP, Cree Inc, TOKYO ELECTRON LTD, SICC Sci & Technol Co Ltd, AIXTRON SE, Infineon Technologies, Amer Elements, Lasertec Corp, MIYAZAKI CONVENT & VISITORS BUREAU, Natl Inst Informat & Commun Technol Int, Exchange Program, Commemorat Org Japan World Exposit 70, Murata Sci Fdn, Inoue Fdn Sci, Kyoto Inst Technol Int Exchange Promot Fund, Fdn Promot Mat Sci & Technol Japan, Telecommunicat Advancement Fdn, Tateisi Sci & Technol Fdn, Panasoic Corp, Sumitomo Elect Ind Ltd, Dow Corning Corp, DENSO CORP, Toyota Motor Corp, Honda R&D Co Ltd, Hitachi Chem Co Ltd, SHOWA DENKO K K, Fuji Elect Co Ltd, TOSHIBA CORP, Hitachi Ltd, ROHM Co Ltd, SHINDENGEN ELECT MFG CO LTD, SICOXS CORP, Sumitomo Corp, SANKEN ELECT CO LTD DE Emitter Turn-off Thyristor; ETO; high voltage; Silicon Carbide ID THYRISTOR AB This study addresses the transient and steady-state performance of a >13 kV SiC ETO as a Solid-State Circuit Breaker (SSCB). The developed SiC-ETO is based on a 1 cm(2), 15 kV SiC p-GTO with an extremely low differential resistance. Static performance of the device, including the on-state voltage drop at different temperatures and different currents has been carried out in this paper. Furthermore, transient performance of the device, including the turn off energy of the device has been studied. Also, the superior performance of the p-type SiC-ETO has been exploited to design and implement a solid-state circuit breaker. The studies verify the superiority of the SiC p-ETO compared to other solid state devices for this application. C1 [Rezaei, Mohammad Ali; Wang, Gangyao; Huang, Alex Q.] North Carolina State Univ, FREEDM Syst Ctr, Raleigh, NC 27695 USA. [Cheng, Lin; Palmour, John W.] Cree Inc, Durham, NC USA. [Scozzie, Charles] US Army, Res Labs, Adelphi, MD 20783 USA. RP Rezaei, MA (reprint author), North Carolina State Univ, FREEDM Syst Ctr, Raleigh, NC 27695 USA. EM mrezaei@ncsu.edu; aqhuang@ncsu.edu; lin_cheng@cree.com RI Huang, Alex/Q-9784-2016 OI Huang, Alex/0000-0003-3427-0335 NR 8 TC 4 Z9 4 U1 0 U2 4 PU TRANS TECH PUBLICATIONS LTD PI DURNTEN-ZURICH PA KREUZSTRASSE 10, 8635 DURNTEN-ZURICH, SWITZERLAND SN 0255-5476 J9 MATER SCI FORUM PY 2014 VL 778-780 BP 1025 EP + DI 10.4028/www.scientific.net/MSF.778-780.1025 PG 3 WC Crystallography; Materials Science, Multidisciplinary SC Crystallography; Materials Science GA BA5GD UT WOS:000336634100244 ER PT S AU Cheng, L Palmour, JW Agarwal, AK Allen, ST Brunt, EV Wang, GY Pala, V Sung, WJ Huang, AQ O'Loughlin, M Burk, A Grider, D Scozzie, C AF Cheng, Lin Palmour, John W. Agarwal, Anant K. Allen, Scott T. Brunt, Edward V. Wang, Gangyao Pala, Vipindas Sung, Woongje Huang, Alex Q. O'Loughlin, Michael Burk, Albert Grider, Dave Scozzie, Charles BE Okumura, H Harima, H Kimoto, T Yoshimoto, M Watanabe, H Hatayama, T Matsuura, H Funaki, T Sano, Y TI Strategic Overview of High-Voltage SiC Power Device Development Aiming at Global Energy Savings SO SILICON CARBIDE AND RELATED MATERIALS 2013, PTS 1 AND 2 SE Materials Science Forum LA English DT Proceedings Paper CT 15th International Conference on Silicon Carbide and Related Materials (ICSCRM) CY SEP 29-OCT 04, 2013 CL Miyazaki, JAPAN SP Japan Soc Appl Phys, Res Inst Appl Sci, Inst Elect, Informat & Commun Engineers, Inst Elect Engineers Japan, Ceram Soc Japan, Surface Sci Soc Japan, Japanese Asso Crystal Growth, Vacuum Soc Japan, MITSUBISHI ELECT CORP, Cree Inc, TOKYO ELECTRON LTD, SICC Sci & Technol Co Ltd, AIXTRON SE, Infineon Technologies, Amer Elements, Lasertec Corp, MIYAZAKI CONVENT & VISITORS BUREAU, Natl Inst Informat & Commun Technol Int, Exchange Program, Commemorat Org Japan World Exposit 70, Murata Sci Fdn, Inoue Fdn Sci, Kyoto Inst Technol Int Exchange Promot Fund, Fdn Promot Mat Sci & Technol Japan, Telecommunicat Advancement Fdn, Tateisi Sci & Technol Fdn, Panasoic Corp, Sumitomo Elect Ind Ltd, Dow Corning Corp, DENSO CORP, Toyota Motor Corp, Honda R&D Co Ltd, Hitachi Chem Co Ltd, SHOWA DENKO K K, Fuji Elect Co Ltd, TOSHIBA CORP, Hitachi Ltd, ROHM Co Ltd, SHINDENGEN ELECT MFG CO LTD, SICOXS CORP, Sumitomo Corp, SANKEN ELECT CO LTD DE Silicon Carbide; High Voltage; MOSFET; GTO; IGBT; Power Diode; Medium-Voltage Drive; Variable Speed Drive; renewable energy conversion; power grid; pulsed power ID 1 CM(2); KV AB Advanced high-voltage (>= 10 kV) silicon carbide (SiC) devices described in this paper have the potential to significantly impact the system size, weight, high-temperature reliability, and cost of modern variable-speed medium-voltage (MV) systems such as variable speed (VSD) drives for electric motors, integration of renewable energy including energy storage, micro-grids, and compact pulsed power systems. In this paper, we review the current status of the development of 10 kV - 20 kV class power devices in SiC, including MOSFETs, JBS diodes, IGBTs, GTO thyristors, and PiN diodes at Cree. Advantages and weakness of each device are discussed and compared. A strategy for high-voltage SiC power device development is proposed. C1 [Cheng, Lin; Palmour, John W.; Allen, Scott T.; Brunt, Edward V.; Wang, Gangyao; Pala, Vipindas; O'Loughlin, Michael; Burk, Albert; Grider, Dave] Cree Inc, 4600 Silicon Dr, Durham, NC 27703 USA. [Agarwal, Anant K.] Dept Energy, Washington, DC USA. [Sung, Woongje; Huang, Alex Q.] North Carolina State Univ, Future Renewable Elect Energy Delivery & Manageme, Durham, NC USA. [Scozzie, Charles] US Army, Res Lab, Adelphi, MD USA. RP Cheng, L (reprint author), Cree Inc, 4600 Silicon Dr, Durham, NC 27703 USA. EM lin_cheng@cree.com RI Huang, Alex/Q-9784-2016 OI Huang, Alex/0000-0003-3427-0335 NR 11 TC 12 Z9 12 U1 1 U2 14 PU TRANS TECH PUBLICATIONS LTD PI DURNTEN-ZURICH PA KREUZSTRASSE 10, 8635 DURNTEN-ZURICH, SWITZERLAND SN 0255-5476 J9 MATER SCI FORUM PY 2014 VL 778-780 BP 1089 EP + DI 10.4028/www.scientific.net/MSF.778-780.1089 PG 2 WC Crystallography; Materials Science, Multidisciplinary SC Crystallography; Materials Science GA BA5GD UT WOS:000336634100258 ER PT S AU Rogers, JG Fink, JR Stump, EA AF Rogers, John G., III Fink, Jonathan R. Stump, Ethan A. GP IEEE TI Mapping with a ground robot in GPS denied and degraded environments SO 2014 AMERICAN CONTROL CONFERENCE (ACC) SE Proceedings of the American Control Conference LA English DT Proceedings Paper CT American Control Conference CY DEC 04-06, 2014 CL Portland, OR SP American Automat Control Council, Boeing, GE Global Res, Honeywell, MathWorks, Mitsubishi Elect Res Lab, National Instruments, Bosch Grp, dSPACE, Eaton, Elsevier, Inst Engn Technol, Maplesoft Engn Solut, Quanser, Soc Ind Appl Math, Springer, Taylor & Francis Grp, Journal Franklin Inst, Visual Solut, Wiley, Swiss Fed Inst Technol Zurich, Dept Mech & Proc Engn AB A robot system operating in an unknown environment must be able to track its position to perform its mission. Vehicles with a consistent view of the sky, e.g., aerial or water surface platforms, can reliably make use of GPS signals to correct accumulated error from inertial measurements and feature-based mapping techniques. However, ground robots that must operate across a wide range of environments suffer from additional constraints which degrade the performance of GPS such as multipath and occlusion. In this paper, we present a methodology for incorporating GPS measurements into a feature-based mapping system for two purposes: providing geo-referenced coordinates for high-level mission execution and correcting accumulated map error over long-term operation. We will present both the underlying system and experimental results from a variety of relevant environments such as military training facilities and large-scale mixed indoor and outdoor environments. C1 [Rogers, John G., III; Fink, Jonathan R.; Stump, Ethan A.] US Army Res Lab, Adelphi, MD 20783 USA. RP Rogers, JG (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM john.g.rogers59.civ@mail.mil; jonathan.r.fink3.civ@mail.mil; ethan.a.stump2.civ@mail.mil NR 23 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 0743-1619 BN 978-1-4799-3274-0 J9 P AMER CONTR CONF PY 2014 PG 6 WC Automation & Control Systems; Engineering, Electrical & Electronic SC Automation & Control Systems; Engineering GA BB8EX UT WOS:000346492602072 ER PT B AU Wierzbicki, TA Lee, IC Gupta, AK AF Wierzbicki, Teresa A. Lee, Ivan C. Gupta, Ashwani K. GP ASME TI THERMAL CHARACTERISTICS OF SYNTHETIC JET FUELS IN A MESO-SCALE HEAT RECIRCULATING COMBUSTOR SO PROCEEDINGS OF THE ASME POWER CONFERENCE, 2013, VOL 1 LA English DT Proceedings Paper CT ASME Power Conference 2013 CY JUL 29-AUG 01, 2013 CL Boston, MA SP ASME, Power Div DE Micro-scale combustion; Heat recirculating combustor; Biofuels and jet fuels; Flame stability; Combustion characteristics AB A meso-scale heat recirculating combustor was used to examine the combustion characteristics of two specific synthetic fuels. One of the fuels was made via a Fischer-Tropsch (F-T fuel) process, while the other was produced from tallow (bio-jet fuel). The two fuels were burned in the meso-scale combustor using pure oxygen in a non-premixed injection configuration. The extinction behavior at the fuel-rich and fuel-lean combustion conditions has been investigated for each fuel. The results showed that although the two fuels showed some similarities, the F-T fuel exhibited stable, non-sooting combustion behavior at higher equivalence ratios than the bio-jet fuel. The lean stability limit for the bio-jet fuel was found to be lower (lower equivalence ratio) than that of the F-T fuel. The results were compared with conventional JP-8 jet fuel to provide a comparative analysis of combustion characteristics using the same combustor. A fuel characterization analysis was' performed for each fuel, and their respective thermal efficiencies calculated. The F-T and bio-jet fuels both reached a maximum thermal efficiency of about 95% near their respective rich extinction limits. C1 [Wierzbicki, Teresa A.; Gupta, Ashwani K.] Univ Maryland, Dept Mech Engn, College Pk, MD 20742 USA. [Lee, Ivan C.] US Army Res Lab, Chem Engn Sensors & Elect Devices Directorate, Adelphi, MD USA. RP Wierzbicki, TA (reprint author), Univ Maryland, Dept Mech Engn, College Pk, MD 20742 USA. FU U.S. Army Research Laboratory FX This research was supported by the U.S. Army Research Laboratory. This support is gratefully acknowledged. Dr. Tim Edwards at the Air Force Research Laboratory is also acknowledged for supplying the fuels tested. Thanks are also due to Dr. Vivek Shirsat and Alexander Booth. NR 15 TC 0 Z9 0 U1 0 U2 1 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-5605-5 PY 2014 AR UNSP V001T01A034 PG 6 WC Energy & Fuels; Engineering, Mechanical SC Energy & Fuels; Engineering GA BC0ZP UT WOS:000349874800034 ER PT J AU Simingalam, S Wijewarnasuriya, P Rao, MV AF Simingalam, Sina Wijewarnasuriya, Priyalal Rao, Mulpuri V. GP IEEE TI Thermal Cycle Annealing and its Application to Arsenic-Ion Implanted HgCdTe SO 2014 20TH INTERNATIONAL CONFERENCE ON ION IMPLANTATION TECHNOLOGY (IIT 2014) LA English DT Proceedings Paper CT 20th International Conference on Ion Implantation Technology (IIT) CY JUN 26-JUL 04, 2014 CL Portland, OR SP Appl Mat, Nissin Ion Equipment Co, Axcelis Technologies Inc, High Voltage Engn, SEN Corp, PLANSEE Electro Graph, Adv Ion Beam Technol Inc, ATMI, Ion Beam Serv, Praxair Inc, CAMECA Instruments Inc, INTEGRATED Engn Software, Kingstone Semicond Co Ltd DE Arsenic; HgCdTe; Dislocation; thermal cycle annealing ID DISLOCATIONS; REDUCTION AB Arsenic ion-implantation is a standard device processing step to create selective area p+-HgCdTe (MCT) regions in planar devices. One of the issues associated with the ion-implantation process is the significant structural damage to the MCT epilayer. These structural defects limit the performance of diodes via significant tunneling reverse-bias dark currents. After ion-implantation, a high temperature annealing step is required to activate the implant (arsenic) by moving it into the tellurium sublattice and also to heal the lattice damage caused by the implantation process. In this study, we have used thermal cycle annealing (TCA) to decrease ion implantation damage. In TCA, we rapidly heat and cool an MCT sample, which provides an additional degree of freedom that is not obtainable with conventional annealing. We have successfully performed TCA for dislocation defect reduction in in-situ indium-doped MCT with limited inter-diffusion between the absorber layer and cadmium rich cap layer. We also investigated the application of TCA to arsenic ion-implanted MCT. Defects were studied using scanning electron microscopy (SEM) after subjecting the samples to Benson etching to decorate the defects. Mercury-deficient and tellurium-saturated overpressure anneals were performed in an attempt to increase mercury vacancy concentrations and, thereby, increase dislocation climb. Such anneals significantly increased the etch pit density (EPD) in both ion-implanted and un-implanted MCT. By cycle annealing, we have also shown EPD reduction in arsenic ion-implanted, long bar shaped MCT mesas formed on CdTe/Si substrates. C1 [Simingalam, Sina] George Mason Univ, Sch Phys Astron & Computat Sci, Fairfax, VA 22030 USA. [Simingalam, Sina; Wijewarnasuriya, Priyalal] US Army Res Lab, Fairfax, VA USA. [Simingalam, Sina; Rao, Mulpuri V.] George Mason Univ, Dept Elect & Comp Engn, Fairfax, VA USA. RP Simingalam, S (reprint author), George Mason Univ, Sch Phys Astron & Computat Sci, Fairfax, VA 22030 USA. EM ssiminga@gmu.edu NR 11 TC 0 Z9 0 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA PY 2014 PG 4 WC Engineering, Electrical & Electronic SC Engineering GA BC0SK UT WOS:000349472200101 ER PT S AU Wang, ZW Wang, ZY Moll, M Huang, PS Grady, D Nasrabadi, N Huang, T Kavraki, L Hasegawa-Johnson, M AF Wang, Zhaowen Wang, Zhangyang Moll, Mark Huang, Po-Sen Grady, Devin Nasrabadi, Nasser Huang, Thomas Kavraki, Lydia Hasegawa-Johnson, Mark GP IEEE TI Active Planning, Sensing and Recognition Using a Resource-Constrained Discriminant POMDP SO 2014 IEEE CONFERENCE ON COMPUTER VISION AND PATTERN RECOGNITION WORKSHOPS (CVPRW) SE IEEE Computer Society Conference on Computer Vision and Pattern Recognition Workshops LA English DT Proceedings Paper CT 27th IEEE Conference on Computer Vision and Pattern Recognition (CVPR) CY JUN 23-28, 2014 CL Columbus, OH SP Comp Vis Fdn, IEEE, IEEE Comp Soc ID OBJECT RECOGNITION AB In this paper, we address the problem of object class recognition via observations from actively selected views/modalities/features under limited resource budgets. A Partially Observable Markov Decision Process (POMDP) is employed to find optimal sensing and recognition actions with the goal of long-term classification accuracy. Heterogeneous resource constraints - such as motion, number of measurements and bandwidth - are explicitly modeled in the state variable, and a prohibitively high penalty is used to prevent the violation of any resource constraint. To improve recognition performance, we further incorporate discriminative classification models with POMDP, and customize the reward function and observation model correspondingly. The proposed model is validated on several data sets for multi-view, multi-modal vehicle classification and multi-view face recognition, and demonstrates improvement in both recognition and resource management over greedy methods and previous POMDP formulations. C1 [Wang, Zhaowen; Wang, Zhangyang; Huang, Po-Sen; Huang, Thomas] Univ Illinois, Beckman Inst, Urbana, IL 61801 USA. [Moll, Mark; Grady, Devin; Kavraki, Lydia] Rice Univ, Dept Comp Sci, Houston, TX 77005 USA. [Nasrabadi, Nasser] US Army, Res Lab, Adelphi, MD 20783 USA. RP Wang, ZW (reprint author), Univ Illinois, Beckman Inst, Urbana, IL 61801 USA. EM wang308@ifp.uiuc.edu; zwang119@ifp.uiuc.edu; mmoll@rice.edu; huang146@ifp.uiuc.edu; devin.grady@rice.edu; nasser.m.nasrabadi.civ@mail.mil; huang@ifp.uiuc.edu; kavraki@rice.edu; jhasegaw@ifp.uiuc.edu OI Moll, Mark/0000-0002-0451-2797 FU U.S. Army Research Laboratory; U.S. Army Research Office [W911NF-09 -1-0383] FX The work is supported by the U.S. Army Research Laboratory and U.S. Army Research Office under grant number W911NF-09 -1-0383 NR 17 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2160-7508 BN 978-1-4799-4309-8 J9 IEEE COMPUT SOC CONF PY 2014 BP 754 EP + DI 10.1109/CVPRW.2014.116 PG 2 WC Computer Science, Artificial Intelligence SC Computer Science GA BC0TW UT WOS:000349552300117 ER PT S AU Li, JW Zhang, LJ Pu, GG Vardi, MY He, JF AF Li, Jianwen Zhang, Lijun Pu, Geguang Vardi, Moshe Y. He, Jifeng BE Schaub, T Friedrich, G OSullivan, B TI LTLf Satisfiability Checking SO 21ST EUROPEAN CONFERENCE ON ARTIFICIAL INTELLIGENCE (ECAI 2014) SE Frontiers in Artificial Intelligence and Applications LA English DT Proceedings Paper CT 21st European Conference on Artificial Intelligence (ECAI) CY AUG 18-22, 2014 CL Czech Tech Univ, Prague, CZECH REPUBLIC SP European Coordinating Comm Artificial Intelligence, Artificial Intelligence Journal, Czech Soc Cybernet & Informat, IOS Press, Univ Potsdam HO Czech Tech Univ ID TEMPORAL LOGICS AB We consider here Linear Temporal Logic (LTL) formulas interpreted over finite traces. We denote this logic by LTLf. The existing approach for LTLf satisfiability checking is based on a reduction to standard LTL satisfiability checking. We describe here a novel direct approach to LTLf satisfiability checking, where we take advantage of the difference in the semantics between LTL and LTLf. While LTL satisfiability checking requires finding a fair cycle in an appropriate transition system, here we need to search only for a finite trace. This enables us to introduce specialized heuristics, where we also exploit recent progress in Boolean SAT solving. We have implemented our approach in a prototype tool and experiments show that our approach outperforms existing approaches. C1 [Li, Jianwen; Pu, Geguang; He, Jifeng] East China Normal Univ, Shanghai, Peoples R China. [Zhang, Lijun] Chinese Acad Sci, Inst Software, State Key Lab Comp Sci, Beijing 100864, Peoples R China. [Vardi, Moshe Y.] Rice Univ, USA, Houston, TX USA. RP Pu, GG (reprint author), East China Normal Univ, Shanghai, Peoples R China. FU Shanghai Knowledge Service Platform [ZE1213]; SHEITC [130407]; NSFC [91118007, 61021004, 61361136002]; NSF [CNS 1049862, CCF-1139011]; NSF Expeditions in Computing project "ExCAPE: Expeditions in Computer Augmented Program Engineering"; BSF [9800096]; Intel FX We thank anonymous reviewers for the useful comments. Geguang Pu is partially supported by Shanghai Knowledge Service Platform No. ZE1213. Jianwen Li is partially supported by SHEITC Project 130407 and NSFC Project No. 91118007. Jifeng He is partially supported by NSFC Project No. 61021004. Lijun Zhang is supported by NSFC project No. 61361136002. Moshe Vardi is supported in part by NSF grants CNS 1049862 and CCF-1139011, by NSF Expeditions in Computing project "ExCAPE: Expeditions in Computer Augmented Program Engineering", by BSF grant 9800096, and by gift from Intel. NR 15 TC 0 Z9 0 U1 0 U2 0 PU IOS PRESS PI AMSTERDAM PA NIEUWE HEMWEG 6B, 1013 BG AMSTERDAM, NETHERLANDS SN 0922-6389 BN 978-1-61499-419-0; 978-1-61499-418-3 J9 FRONT ARTIF INTEL AP PY 2014 VL 263 BP 513 EP + DI 10.3233/978-1-61499-419-0-513 PG 2 WC Computer Science, Artificial Intelligence; Computer Science, Theory & Methods SC Computer Science GA BC0RS UT WOS:000349444700087 ER PT S AU Camarillo, IG Xiao, FN Madhivanan, S Salameh, T Nichols, M Reece, LM Leary, JF Otto, K Natarajan, A Ramesh, A Sundararajan, R AF Camarillo, Ignacio G. Xiao, Funian Madhivanan, S. Salameh, Therese Nichols, Maxine Reece, Lisa M. Leary, James F. Otto, Kevin Natarajan, Arutselvan Ramesh, A. Sundararajan, Raji BE Sundararajan, R TI Low and high voltage electrochemotherapy for breast cancer: an in vitro model study SO ELECTROPORATION-BASED THERAPIES FOR CANCER: FROM BASICS TO CLINICAL APPLICATIONS SE Woodhead Publishing Series in Biomedicine LA English DT Article; Book Chapter DE breast cancer; MCF-7 cells; doxorubicin; paclitaxel; tamoxifen; curcumin; turmeric; electrochemotherapy; impedance spectroscopy; flow cytometry ID ELECTRICAL-IMPEDANCE SPECTROSCOPY; TAXOL-INDUCED APOPTOSIS; NITRIC-OXIDE PRODUCTION; MULTIPLE-SCLEROSIS; DIETARY COMPOUNDS; CELL-LINE; CURCUMIN; ELECTROPORATION; EXPERIENCE; GROWTH AB The death of a woman every 71 seconds in the world and every 12 minutes in the US, from breast cancer, indicate that the current standard of cure does not work. In addition, these therapies are expensive and have many side effects. This calls for safe, effective, alternate, affordable and physical therapies. Electrochemotherapy (ECT) has promising potential for treating inoperable, chemo-resistant and radio-resistant tumors that do not respond to the current standard of cure. Clinical trials show the successful applications of ECT for chest wall breast carcinomas. In this research, the efficacy of FDA approved, commonly prescribed and administered breast cancer drugs, including doxorubicin, paclitaxol, tamoxifen and bleomycin are studied using electroporation. In addition, the efficacy of curcumin is also studied using high and low voltage electroporation. MCF-7 breast cancer cells were used for this study at various pulse parameter conditions, including both low and high voltages. The positive results indicate that ECT is a good vehicle to efficiently upload these drugs intratumorally. C1 [Camarillo, Ignacio G.; Nichols, Maxine] Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USA. [Camarillo, Ignacio G.] Univ Calif Santa Cruz, Dept Mol Cellular & Dev Biol, Santa Cruz, CA 95064 USA. [Madhivanan, S.] KAPV Govt Med Coll, Tiruchchirappalli, India. [Reece, Lisa M.] Purdue Univ, Birck Nanotechnol Ctr, W Lafayette, IN 47907 USA. [Reece, Lisa M.] UT El Paso, El Paso, TX 79968 USA. [Reece, Lisa M.] William Beaumont Army Med Ctr, Ft Bliss, TX USA. [Reece, Lisa M.] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA. [Reece, Lisa M.] UT Med Branch, Galveston, TX USA. [Leary, James F.] Purdue Univ, W Lafayette, IN 47907 USA. [Otto, Kevin] Purdue Univ, NeuroProstheses Res Lab, W Lafayette, IN 47907 USA. [Natarajan, Arutselvan] Stanford Univ, Stanford, CA 94305 USA. [Ramesh, A.] Sri Ramachandra Univ, Sri Ramachandra Med Coll & Res Inst, Dept Gen Med, Madras, Tamil Nadu, India. [Sundararajan, Raji] Purdue Univ, Elect & Comp Engn Technol Dept, W Lafayette, IN 47907 USA. RP Camarillo, IG (reprint author), Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USA. NR 59 TC 0 Z9 0 U1 0 U2 0 PU WOODHEAD PUBL LTD PI CAMBRIDGE PA ABINGTON HALL ABINGTON, CAMBRIDGE CB1 6AH, CAMBS, ENGLAND SN 2050-0289 BN 978-1-908818-29-4; 978-1-907568-15-2 J9 WOODH PUB SER BIOMED PY 2014 IS 49 BP 55 EP 102 DI 10.1533/9781908818294.55 PG 48 WC Oncology SC Oncology GA BC0CU UT WOS:000348916300005 ER PT J AU Bianchini, A AF Bianchini, Alessandra TI Frohlich Theory-Based Approach for Analysis of Stress Distribution in a Layered System Case Study SO TRANSPORTATION RESEARCH RECORD LA English DT Article AB The California bearing ratio (CBR) procedure for the design of airfield flexible pavements was originally developed in the 1940s for supporting new heavy bombers and reviewed in the 1970s to allow handling multiwheel tire groups. In view of an active debate at the International Civil Aviation Organization level on further adjustments to the design procedure, a U.S. Army Engineer Research and Development Center (ERDC) research team reformulated the original CBR procedure. The new CBR design procedure was redefined with the introduction of Frohlich's theory for computing the pavement thickness and validated through full-scale testing. This study evaluated the influence of each layer in the stress distribution with the final objective of recommending specific values of the Frohlich stress concentration factor. The data for this investigation were collected during full-scale testing at the ERDC in 2008. The analysis allowed identification of several influencing factors in the stress distribution for computing the stress acting at the top of the subgrade. Such factors included the subbase and subgrade CBR, the thickness of the subbase layer, and the stress distribution represented by the respective it factor of the layer group. The linear regression confirmed the statistical importance of these variables in assessing stress distribution above the subgrade. This case study provided encouraging results for additional investigations on the stress distribution within a layered system with the objective of quantifying more accurately the stress acting at the top of the subgrade. C1 [Bianchini, Alessandra] US Army Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. RP Bianchini, A (reprint author), Air Force Civil Engn Ctr, 138 Barnes Dr,Suite 2, Tyndall AFB, FL 32403 USA. EM alessandra.bianchini@usace.army.mil NR 16 TC 0 Z9 0 U1 1 U2 1 PU NATL ACAD SCIENCES PI WASHINGTON PA 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA SN 0361-1981 EI 2169-4052 J9 TRANSPORT RES REC JI Transp. Res. Record PY 2014 IS 2462 BP 61 EP 67 DI 10.3141/2462-08 PG 7 WC Engineering, Civil; Transportation; Transportation Science & Technology SC Engineering; Transportation GA CB2YX UT WOS:000349495500009 ER PT J AU Sato, M Kadota, M Tang, B Yang, HH Yang, YA Shan, M Weng, J Welsh, MA Flanders, KC Nagano, Y Michalowski, AM Clifford, RJ Lee, MP Wakefield, LM AF Sato, Misako Kadota, Mitsutaka Tang, Binwu Yang, Howard H. Yang, Yu-an Shan, Mengge Weng, Jia Welsh, Michael A. Flanders, Kathleen C. Nagano, Yoshiko Michalowski, Aleksandra M. Clifford, Robert J. Lee, Maxwell P. Wakefield, Lalage M. TI An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-beta in human breast cancer SO BREAST CANCER RESEARCH LA English DT Article ID MAMMARY EPITHELIAL-CELLS; GENE-EXPRESSION SIGNATURE; TGF-BETA; SIGNALING PATHWAY; CARCINOMA-CELLS; EPHA RECEPTOR; SMAD PROTEINS; MCF10AT CELLS; PROGRESSION; METASTASIS AB Introduction: Transforming growth factor-beta s (TGF-beta s) play a dual role in breast cancer, with context-dependent tumor-suppressive or pro-oncogenic effects. TGF-beta antagonists are showing promise in early-phase clinical oncology trials to neutralize the pro-oncogenic effects. However, there is currently no way to determine whether the tumor-suppressive effects of TGF-beta are still active in human breast tumors at the time of surgery and treatment, a situation that could lead to adverse therapeutic responses. Methods: Using a breast cancer progression model that exemplifies the dual role of TGF-beta, promoter-wide chromatin immunoprecipitation and transcriptomic approaches were applied to identify a core set of TGF-beta-regulated genes that specifically reflect only the tumor-suppressor arm of the pathway. The clinical significance of this signature and the underlying biology were investigated using bioinformatic analyses in clinical breast cancer datasets, and knockdown validation approaches in tumor xenografts. Results: TGF-beta-driven tumor suppression was highly dependent on Smad3, and Smad3 target genes that were specifically enriched for involvement in tumor suppression were identified. Patterns of Smad3 binding reflected the preexisting active chromatin landscape, and target genes were frequently regulated in opposite directions in vitro and in vivo, highlighting the strong contextuality of TGF-beta action. An in vivo-weighted TGF-beta/Smad3 tumor-suppressor signature was associated with good outcome in estrogen receptor-positive breast cancer cohorts. TGF-beta/Smad3 effects on cell proliferation, differentiation and ephrin signaling contributed to the observed tumor suppression. Conclusions: Tumor-suppressive effects of TGF-beta persist in some breast cancer patients at the time of surgery and affect clinical outcome. Carefully tailored in vitro/in vivo genomic approaches can identify such patients for exclusion from treatment with TGF-beta antagonists. C1 [Sato, Misako; Tang, Binwu; Yang, Yu-an; Shan, Mengge; Weng, Jia; Welsh, Michael A.; Flanders, Kathleen C.; Nagano, Yoshiko; Michalowski, Aleksandra M.; Wakefield, Lalage M.] Natl Canc Inst, Ctr Canc Res, Lab Canc Biol & Genet, Bethesda, MD 20892 USA. [Kadota, Mitsutaka; Yang, Howard H.; Clifford, Robert J.; Lee, Maxwell P.] NCI, Ctr Canc Res, Lab Populat Genet, Bethesda, MD 20892 USA. [Sato, Misako] Osaka City Univ, Grad Sch Med, Dept Hepatol, Abeno Ku, Osaka 5458585, Japan. [Kadota, Mitsutaka] RIKEN, Ctr Dev Biol, Genome Resource & Anal Unit, Kobe, Hyogo 6500047, Japan. [Nagano, Yoshiko] Tokyo Med & Dent Univ, Dept Immunotherapeut, Bunkyo Ku, Tokyo 1138519, Japan. [Clifford, Robert J.] Walter Reed Army Inst Res, Silver Spring, MD 20910 USA. RP Wakefield, LM (reprint author), Natl Canc Inst, Ctr Canc Res, Lab Canc Biol & Genet, 37 Convent Dr, Bethesda, MD 20892 USA. EM lw34g@nih.gov FU Japan Society for the Promotion of Sciences Fellowships; Intramural Research Program of the NIH, National Cancer Institute, Center for Cancer Research [ZIA BC 005785] FX The authors thank Drs. Kent Hunter, Glenn Merlino, Stuart Yuspa and Tsutomu Matsubara for critical reading of the manuscript and helpful discussions, Dr. Xaolin Wu for performing the microarrays, and Anthony Vieira for help with the animal studies. Misako Sato and Yoshiko Nagano were supported by the Japan Society for the Promotion of Sciences Fellowships. This research was supported by the Intramural Research Program of the NIH, National Cancer Institute, Center for Cancer Research ZIA BC 005785 (LMW). NR 86 TC 4 Z9 4 U1 0 U2 4 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1465-542X EI 1465-5411 J9 BREAST CANCER RES JI Breast Cancer Res. PY 2014 VL 16 IS 3 AR R57 DI 10.1186/bcr3668 PG 23 WC Oncology SC Oncology GA CA7FT UT WOS:000349083900013 PM 24890385 ER PT S AU Tagliente, DA Lyding, C Zawislak, J Marston, D AF Tagliente, Daniel A. Lyding, Charles Zawislak, Joshua Marston, Derek GP IEEE TI Expanding Emulation from Test to Create Realistic Virtual Training Environments SO 2014 IEEE AUTOTESTCON SE IEEE Autotestcon LA English DT Proceedings Paper CT 50th Anniversary of IEEE AUTOTEST Conference CY SEP 15-18, 2014 CL St Louis, MO SP IEEE, IEEE Aerosp & Elect Syst Soc, IEEE Instrumentat & Measurement Soc DE testing; emulation; training; virtual environment; maintenance AB A plurality of emulated systems is used to create a realistic virtual training environment. Retaining an open architecture allows emulator components to be swapped with physical hardware to create a more expansive variety of virtual training and test environments, as well as to abstract the user from the underlying hardware emulation. This allows for the creation of a low cost training environment that can easily and inexpensively be duplicated at many training locations. An example of emulation developed for test but later adapted and expanded for training is presented. High-fidelity emulators of individual line replaceable units are combined to form larger emulated systems, which comprise a suite of training products. An open architecture allows for a subset of these training products to communicate and operate with one another within a virtual training environment. The training products presented range from those operated on a personal computer with no product-representative hardware to full-scale simulators in which the end-user is almost completely abstracted from the underlying hardware emulation, thus providing a realistic, low cost, and effective training experience. C1 [Tagliente, Daniel A.; Lyding, Charles; Zawislak, Joshua; Marston, Derek] United States Army, ARDEC, Automated Test Syst Div, Picatinny Arsenal, NJ 07885 USA. RP Tagliente, DA (reprint author), United States Army, ARDEC, Automated Test Syst Div, Picatinny Arsenal, NJ 07885 USA. NR 4 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1088-7725 BN 978-1-4799-3005-0 J9 IEEE AUTOTESTCON PY 2014 PG 5 WC Automation & Control Systems; Engineering, Electrical & Electronic SC Automation & Control Systems; Engineering GA BB9WL UT WOS:000348736600026 ER PT B AU Morrow, S Hart, A AF Morrow, Sean Hart, Alexis BE Doe, S Langstraat, L TI VETERANS IN COLLEGE WRITING CLASSES Understanding and Embracing the Mutual Benefit SO GENERATION VET: COMPOSITION, STUDENT-VETERANS, AND THE POST-9/11 UNIVERSITY LA English DT Article; Book Chapter C1 [Morrow, Sean] US Army, Washington, DC 20310 USA. [Hart, Alexis] Allegheny Coll, Meadville, PA 16335 USA. RP Morrow, S (reprint author), US Army, Washington, DC 20310 USA. NR 29 TC 0 Z9 0 U1 0 U2 0 PU UTAH STATE UNIV PRESS PI LOGAN PA UTAH STATE UNIV, LOGAN, UTAH 84322 USA BN 978-0-87421-942-5; 978-0-87421-941-8 PY 2014 BP 31 EP 50 DI 10.7330/9780874219425.c0001 D2 10.7330/9780874219425 PG 20 WC Education & Educational Research SC Education & Educational Research GA BB8NB UT WOS:000346977000002 ER PT B AU Hadlock, E Doe, S AF Hadlock, Erin Doe, Sue BE Doe, S Langstraat, L TI NOT JUST "YES SIR, NO SIR" How Genre and Agency Interact in Student-Veteran Writing SO GENERATION VET: COMPOSITION, STUDENT-VETERANS, AND THE POST-9/11 UNIVERSITY LA English DT Article; Book Chapter C1 [Hadlock, Erin] US Mil Acad, West Point, NY 10996 USA. [Hadlock, Erin] US Army, Washington, DC USA. [Doe, Sue] Colorado State Univ, Ft Collins, CO 80523 USA. RP Hadlock, E (reprint author), US Mil Acad, West Point, NY 10996 USA. NR 19 TC 0 Z9 0 U1 0 U2 0 PU UTAH STATE UNIV PRESS PI LOGAN PA UTAH STATE UNIV, LOGAN, UTAH 84322 USA BN 978-0-87421-942-5; 978-0-87421-941-8 PY 2014 BP 73 EP 94 DI 10.7330/9780874219425.c003 D2 10.7330/9780874219425 PG 22 WC Education & Educational Research SC Education & Educational Research GA BB8NB UT WOS:000346977000004 ER PT J AU Esposito, ER Rodriguez, KM Rabago, CA Wilken, JM AF Esposito, Elizabeth Russell Rodriguez, Kelly M. Rabago, Christopher A. Wilken, Jason M. TI Does unilateral transtibial amputation lead to greater metabolic demand during walking? SO JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT LA English DT Article DE amputee; energetics; gait; heart rate; military; oxygenm consumption; prosthetic; servicemember; speed; traumatic ID BELOW-KNEE AMPUTEES; LOWER-LIMB AMPUTATIONS; TRANS-TIBIAL AMPUTEES; ENERGY-EXPENDITURE; DESTABILIZING ENVIRONMENTS; GAIT CHARACTERISTICS; MALE SERVICEMEMBERS; PHYSICAL-ACTIVITY; PROSTHETIC FEET; ROCK SURFACE AB Previous literature reports greater metabolic demand of walking following transtibial amputation. However, most research focuses on relatively older, less active, and often dysvascular amputees. Servicemembers with traumatic amputation are typically young, fit, and highly active before and often following surgical amputation of their lower limb. This study compared the metabolic demand of walking in young, active individuals with traumatic unilateral transtibial amputation (TTA) and nondisabled controls. Heart rate (HR), rate of oxygen consumption, and rating of perceived exertion (RPE) were calculated as subjects walked at a self-selected velocity and at five standardized velocities based on leg length. The TTA group completed a Prosthetics Evaluation Questionnaire. Oxygen consumption (p = 0.89), net oxygen consumption (p = 0.32), and RPE (p = 0.14) did not differ between groups. Compared with controls, HR was greater in the TTA group and increased to a greater extent with velocity (p < 0.001). Overall, the TTA group rated their walking abilities as high (mean: 93% out of 100%). This is the first study to report equivalent metabolic demand between persons with amputation and controls walking at the same velocity. These results may reflect the physical fitness of the young servicemembers with traumatic amputations and may serve to guide outcome expectations in the future. C1 [Esposito, Elizabeth Russell; Rodriguez, Kelly M.; Rabago, Christopher A.; Wilken, Jason M.] Brooke Army Med Ctr, Ctr Intrepid, Dept Orthopaed & Rehabil, Ft Sam Houston, TX 78234 USA. [Esposito, Elizabeth Russell; Rabago, Christopher A.; Wilken, Jason M.] Ctr Excellence, Dept Vet Affairs Extrem Trauma & Amputat, Dept Def, New York, NY USA. RP Esposito, ER (reprint author), Ctr Intrepid, 3551 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA. EM Erussell.kin@gmail.com OI Wilken, Jason/0000-0002-5556-7667; Rabago, Christopher/0000-0002-4484-0613 FU Telemedicine and Advanced Technology Research Center; Military Amputee Research Program [W81XWH-06-2-0073] FX This material was based on work supported by the Telemedicine and Advanced Technology Research Center and the Military Amputee Research Program (contract W81XWH-06-2-0073). NR 43 TC 7 Z9 7 U1 5 U2 10 PU JOURNAL REHAB RES & DEV PI BALTIMORE PA DEPT OF VETERANS AFFAIRS REHABIL RES & DEVELOP CTR 103 SOUTH GAY STREET, BALTIMORE, MD 21202-4051 USA SN 0748-7711 EI 1938-1352 J9 J REHABIL RES DEV JI J. Rehabil. Res. Dev. PY 2014 VL 51 IS 8 BP 1287 EP 1296 DI 10.1682/JRRD.2014.06.0141 PG 10 WC Rehabilitation SC Rehabilitation GA CA2ZZ UT WOS:000348776400011 PM 25671680 ER PT B AU Zweibelson, B Martin, G Paparone, C AF Zweibelson, Ben Martin, Grant Paparone, Chris BE Grace, M Graen, GB TI THE TIMES THEY ARE A-CHANGIN' ... ARE WE? Frame-Changing Design for Military Interventions SO MILLENNIAL SPRING: DESIGNING THE FUTURE OF ORGANIZATIONS SE LMX Leadership Series LA English DT Article; Book Chapter AB These three military authors offer a unique perspective into design thinking and military sense-making. They offer an argument that while the military as an institution prefers to make sense of the world through a systems-analytic paradigm that is increasingly problematic, a frame-changing design approach is needed instead. This approach requires a greater appreciation of uncertainty and the awareness that new knowledge production must emerge from beyond the single preferred military paradigm. C1 [Zweibelson, Ben; Paparone, Chris] US Army, Washington, DC 20310 USA. [Martin, Grant] US Army, John F Kennedy Special Warfare Ctr & Sch, Washington, DC USA. RP Zweibelson, B (reprint author), US Army, Washington, DC 20310 USA. NR 45 TC 0 Z9 0 U1 0 U2 0 PU INFORMATION AGE PUBLISHING-IAP PI CHARLOTTE PA PO BOX 79049, CHARLOTTE, NC 28271-7047 USA BN 978-1-62396-744-4; 978-1-62396-745-1 J9 LMX LEADERSH SER PY 2014 BP 191 EP 224 PG 34 WC Management SC Business & Economics GA BB9ER UT WOS:000348240400011 ER PT S AU Sun, WB Baize, RR Videen, G AF Sun, Wenbo Baize, Rosemary R. Videen, Gorden BE Im, E Yang, S Zhang, P TI A Review of the Super-thin Clouds Detection Algorithm SO REMOTE SENSING OF THE ATMOSPHERE, CLOUDS, AND PRECIPITATION V SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Remote Sensing of the Atmosphere, Clouds, and Precipitation V CY OCT 13-15, 2014 CL Beijing, PEOPLES R CHINA SP SPIE, State Key Lab Remote Sensing Sci, Natl Aeronaut & Space Adm, Minist Earth Sci DE Super-thin clouds; detection; polarized sunlight; retrieval of optical thickness ID CLEAR-SKY; CIRRUS; MODIS AB In this work, the super-thin cloud detection algorithm [1], that uses the polarization angle of the backscattered solar radiation to find the super-thin clouds, is briefly reviewed and the retrieval of the optical thickness of these clouds is proposed. We found that at the neighborhood angles of the backscattering direction, these clouds can be reliably detected. The polarized components of the reflected light may be used to retrieve the optical thickness of these clouds. C1 [Sun, Wenbo] Sci Syst & Applications Inc, Hampton, VA 23666 USA. [Sun, Wenbo; Baize, Rosemary R.] NASA, Langley Res Ctr, Hampton, VA 23681 USA. [Videen, Gorden] Space Sci Inst, Boulder, CO 80301 USA. [Videen, Gorden] US Army, Res Lab, Adelphi, MD 20783 USA. RP Sun, WB (reprint author), Sci Syst & Applications Inc, Hampton, VA 23666 USA. FU NASA Glory fund [09-GLORY09-0027] FX This work was supported by NASA Glory fund 09-GLORY09-0027. The authors thank Hal B. Maring for this support. NR 17 TC 0 Z9 0 U1 0 U2 0 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-326-7 J9 PROC SPIE PY 2014 VL 9259 DI 10.1117/12.2067779 PG 4 WC Environmental Sciences; Meteorology & Atmospheric Sciences; Optics SC Environmental Sciences & Ecology; Meteorology & Atmospheric Sciences; Optics GA BB9ZL UT WOS:000348833900009 ER PT J AU Gross, BGRC AF Gross, Brigadier General Richard C. TI Lieber Conference Keynote Address SO COLUMBIA JOURNAL OF TRANSNATIONAL LAW LA English DT Article AB Brigadier General Gross delivered the keynote address at the 2013 Lieber Conference, From Gettysburg to Guantanamo: 150 Years of the Lieber Code and the Law of Armed Conflict, hosted at Columbia Law School on November 21, 2013. C1 [Gross, Brigadier General Richard C.] 82nd Airborne Div, Ft Bragg, NC USA. [Gross, Brigadier General Richard C.] US Cent Command, Tampa, FL USA. NR 0 TC 0 Z9 0 U1 0 U2 1 PU COLUMBIA JOURNAL TRANSNATIONAL LAW ASSOC PI NEW YORK PA COLUMBIA UNIV, SCHOOL LAW, 435 W 116TH ST, NEW YORK, NY 10027 USA SN 0010-1931 EI 2159-1814 J9 COLUMBIA J TRANS LAW JI Columbia J. Transnatl. Law PY 2014 VL 53 IS 1 BP 97 EP 104 PG 8 WC International Relations; Law SC International Relations; Government & Law GA AZ1NF UT WOS:000348004900005 ER PT B AU Mejias-Santiago, M Doyle, JD Rushing, JF AF Mejias-Santiago, Mariely Doyle, Jesse D. Rushing, John F. BE Kim, YR TI Workability of WMA and WMA-RAP mixtures and relationship to field compaction SO ASPHALT PAVEMENTS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 12th ISAP International Conference on Asphalt Pavements CY JUN 01-05, 2014 CL Raleigh, NC SP ISAP, Carolina Asphalt Pavement Assoc, TROXLER, Korea Inst Construct Technol, InstroTek Inc, Natl Asphalt Pavement Assoc, Dongre Lab Serv Inc, Heritage Grp DE Warm Mix Asphalt; WMA; RAP; workability; compactability ID WARM-MIX ASPHALT; PAVEMENT MATERIAL; PERFORMANCE AB The terms workability and compactability have been applied to asphalt mixtures to describe the relative ease with which material can be placed, hand worked, or compacted. A number of methods described in literature have been investigated to quantify this parameter, including devices that measure the torque required to rotate a mixing paddle through a sample of asphalt mixture. An improved workability measurement device based on that concept is described in this paper. Data collected with this device for seventeen mixtures are presented. The mixtures included both Hot Mix Asphalt (HMA) and Warm Mix Asphalt (WMA). WMA was produced with Sasobit (R) additive, Evotherm (TM) 3G additive, and by asphalt binder foaming. Reclaimed Asphalt Pavement (RAP) contents of 25 and 50% were also investigated for HMA and WMA. Four of the mixtures without RAP, including HMA and one of each WMA, were produced at an asphalt plant and placed into test strips with full scale construction equipment. Compaction of the pavement mat was monitored by embedded thermocouples, and nuclear density gauge measurements were taken between successive roller compactor passes. The relationship between laboratory measurement of workability and the relative ease of field compaction is investigated. C1 [Mejias-Santiago, Mariely; Doyle, Jesse D.; Rushing, John F.] US Army Engn Res & Dev Ctr, Vicksburg, MS 39180 USA. RP Mejias-Santiago, M (reprint author), US Army Engn Res & Dev Ctr, Vicksburg, MS 39180 USA. NR 13 TC 0 Z9 0 U1 1 U2 1 PU CRC PRESS-TAYLOR & FRANCIS GROUP PI BOCA RATON PA 6000 BROKEN SOUND PARKWAY NW, STE 300, BOCA RATON, FL 33487-2742 USA BN 978-1-315-73675-4; 978-1-138-02693-3 PY 2014 BP 1027 EP 1035 PG 9 WC Construction & Building Technology; Engineering, Environmental; Engineering, Civil SC Construction & Building Technology; Engineering GA BB8SH UT WOS:000347408100096 ER PT S AU Pritchett, TM Ferry, MJ Shensky, WM Mott, AG Pei, CK Sun, WF AF Pritchett, Timothy M. Ferry, Michael J. Shensky, William M., III Mott, Andrew G. Pei, Chengkui Sun, Wenfang BE Nunzi, JM TI Engineering the ground- and excited-state absorption spectra of broadband reverse saturable absorbers SO LIGHT MANIPULATING ORGANIC MATERIALS AND DEVICES SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Light Manipulating Organic Materials and Devices CY AUG 20-21, 2014 CL San Diego, CA SP SPIE DE Reverse saturable absorption; organic nonlinear optical materials ID CATIONIC IRIDIUM(III) COMPLEXES; BOOLEAN-AND-N; PLATINUM(II) COMPLEX; SINGLE-BEAM; PHOTOPHYSICS; EMISSION; LIGANDS AB We exploit the strong spin-orbit coupling in iridium to modify the linear absorption spectrum of a novel iridium(III) complex so as to broaden the spectral region over which it exhibits reverse saturable absorption. We discuss the design of the new chromophore, present its ground-state absorption spectrum, and report values of its singlet excited-state lifetime and singlet and triplet excited-state absorption cross sections, determined from femtosecond transient difference absorption measurements and nanosecond and picosecond open-aperture Z scans. C1 [Pritchett, Timothy M.; Ferry, Michael J.; Shensky, William M., III; Mott, Andrew G.] US Army Res Lab, Attn RDRL SEE M, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. [Pei, Chengkui; Sun, Wenfang] North Dakota State Univ, Dept Chem & Biochem, Fargo, ND 58108 USA. RP Pritchett, TM (reprint author), US Army Res Lab, Attn RDRL SEE M, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM timothy.m.pritchett.civ@mail.mil NR 14 TC 0 Z9 0 U1 0 U2 6 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-208-6 J9 PROC SPIE PY 2014 VL 9181 AR UNSP 918104 DI 10.1117/12.2059282 PG 9 WC Optics; Physics, Applied SC Optics; Physics GA BB9BG UT WOS:000348035800001 ER PT S AU Osgood, RM Bullion, KM Giardini, SA Carlson, JB Stenhouse, P Kingsborough, R Liberman, V Parameswaran, L Rothschild, M Miller, O Kooi, S Joannopoulos, J Jeffrey, F Braymen, S Gill, HS Kumar, J AF Osgood, R. M., III Bullion, K. M. Giardini, S. A. Carlson, J. B. Stenhouse, P. Kingsborough, R. Liberman, V. Parameswaran, L. Rothschild, M. Miller, O. Kooi, S. Joannopoulos, J. Jeffrey, F. Braymen, S. Gill, H. Singh Kumar, J. BE Sulima, OV Conibeer, G TI Scattering of long wavelengths into thin silicon photovoltaic films by plasmonic silver nanoparticles SO NEXT GENERATION TECHNOLOGIES FOR SOLAR ENERGY CONVERSION V SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Next Generation Technologies for Solar Energy Conversion V CY AUG 19-20, 2014 CL San Diego, CA SP SPIE DE Photovoltaics; flexible thin films; amorphous silicon; nanoparticles; scattering; absorption; diffuse scattering; specular reflectivity; efficiency enhancement; NIR/visible spectrum; optical properties ID SOLAR-CELLS; EFFICIENCY AB Nanoparticles and nanostructures with plasmonic resonances are currently being employed to enhance the efficiency of solar cells.(1-3) Ag stripe arrays have been shown theoretically to enhance the short-circuit current of thin silicon layers.(4) Monolayers of Ag nanoparticles with diameter d < 300 nm have shown strong plasmonic resonances when coated in thin polymer layers with thicknesses < d(5). We study experimentally the diffuse vs. specular scattering from monolayer arrays of Ag nanoparticles (spheres and prisms with diameters in the range 50 - 300 nm) coated onto the front side of thin (100 nm < t < 500 nm) silicon films deposited on glass and flexible polymer substrates, the latter originating in a roll-to-roll manufacturing process. Ag nanoparticles are held in place and aggregation is prevented with a polymer overcoat. We observe interesting wavelength shifts between maxima in specular and diffuse scattering that depend on particle size and shape, indicating that the nanoparticles substantially modify the scattering into the thin silicon film. C1 [Osgood, R. M., III; Bullion, K. M.; Giardini, S. A.; Carlson, J. B.; Stenhouse, P.] US Army, Natick Soldier Res Dev & Engn Ctr, Natick, MA 01760 USA. [Kingsborough, R.; Liberman, V.; Parameswaran, L.; Rothschild, M.] MIT, Lincoln Lab, Lexington, MA 02420 USA. [Miller, O.; Kooi, S.; Joannopoulos, J.] MIT, Inst Soldier Nanotechnol, Cambridge, MA 02139 USA. [Jeffrey, F.; Braymen, S.] PowerFilm Inc, Ames, IA 80401 USA. [Gill, H. Singh; Kumar, J.] Univ Massachusetts, Dept Phys, Lowell, MA 01854 USA. RP Osgood, RM (reprint author), US Army, Natick Soldier Res Dev & Engn Ctr, Natick, MA 01760 USA. FU Army Research Office through the Institute for Soldier Nanotechnologies [W911NF-07-D0004] FX The MIT ISN authors acknowledge funding from the Army Research Office through the Institute for Soldier Nanotechnologies under Contract No. W911NF-07-D0004. NR 11 TC 0 Z9 0 U1 0 U2 0 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-205-5 J9 PROC SPIE PY 2014 VL 9178 AR UNSP 91780I DI 10.1117/12.2062268 PG 16 WC Chemistry, Applied; Energy & Fuels; Optics; Physics, Applied SC Chemistry; Energy & Fuels; Optics; Physics GA BB9BE UT WOS:000348035200005 ER PT S AU Palmour, JW Cheng, L Pala, V Brunt, EV Lichtenwalner, DJ Wang, GY Richmond, J O'Loughlin, M Ryu, S Allen, ST Burk, AA Scozzie, C AF Palmour, J. W. Cheng, L. Pala, V. Brunt, E. V. Lichtenwalner, D. J. Wang, G-Y Richmond, J. O'Loughlin, M. Ryu, S. Allen, S. T. Burk, A. A. Scozzie, C. GP IEEE TI Silicon Carbide Power MOSFETs: Breakthrough Performance from 900 V up to 15 kV SO 2014 IEEE 26TH INTERNATIONAL SYMPOSIUM ON POWER SEMICONDUCTOR DEVICES & IC'S (ISPSD) SE Proceedings of the International Symposium on Power Semiconductor Devices & ICs LA English DT Proceedings Paper CT IEEE 26th International Symposium on Power Semiconductor Devices & IC's (ISPSD) CY JUN 15-19, 2014 CL Waikoloa, HI SP IEEE AB Since Cree, Inc.'s 2nd generation 4H-SiC MOSFETs were commercially released with a specific on-resistance (R-ON,R-SP) of 5 m Omega.cm(2) for a 1200 V-rating in early 2013, we have further optimized the device design and fabrication processes as well as greatly expanded the voltage ratings from 900 V up to 15 kV for a much wider range of high-power, high-frequency, and high-voltage energy-conversion and transmission applications. Using these next-generation SiC MOSFETs, we have now achieved new breakthrough performance for voltage ratings from 900 V up to 15 kV with a RON, SP as low as 2.3 m Omega.cm(2) for a breakdown voltage (BV) of 1230 V and 900 V-rating, 2.7 m Omega.cm(2) for a BV of 1620 V and 1200 V-rating, 3.38 m Omega.cm(2) for a BV of 1830 V and 1700 V-rating, 10.6 m Omega.cm(2) for a BV of 4160 V and 3300 Vrating, 123 m Omega.cm(2) for a BV of 12 kV and 10 kV-rating, and 208 m Omega.cm(2) for a BV of 15.5 kV and 15 kV-rating. In addition, due to the lack of current tailing during the bipolar device switching turn-off, the SiC MOSFETs reported in this work exhibit incredibly high frequency switching performance over their silicon counter parts. C1 [Palmour, J. W.; Cheng, L.; Pala, V.; Brunt, E. V.; Lichtenwalner, D. J.; Wang, G-Y; Richmond, J.; O'Loughlin, M.; Ryu, S.; Allen, S. T.; Burk, A. A.] Cree Inc, 4600 Silicon Dr, Durham, NC 27703 USA. [Scozzie, C.] US Army, Res Lab, Adelphi, MD 2800 USA. RP Palmour, JW (reprint author), Cree Inc, 4600 Silicon Dr, Durham, NC 27703 USA. EM John_Palmour@cree.com; Lin_Cheng@cree.com FU U.S. Army Research Laboratory located at Adelphi, MD, USA FX This work was funded by U.S. Army Research Laboratory located at Adelphi, MD, USA. NR 3 TC 21 Z9 24 U1 2 U2 5 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1063-6854 BN 978-1-4799-2918-4 J9 PROC INT SYMP POWER PY 2014 BP 79 EP 82 PG 4 WC Computer Science, Hardware & Architecture; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BB8JG UT WOS:000346735500018 ER PT S AU Lawson, K Schrock, J Ray, W Bayne, S Cheng, L Palmour, J Allen, S AF Lawson, K. Schrock, J. Ray, W., II Bayne, S. Cheng, L. Palmour, J. Allen, S. GP IEEE TI Ruggedness Evaluation of 56mm(2), 180 A SiC DMOSFETs as a Function of Pulse Repetition Rate for High Power Applications SO 2014 IEEE 26TH INTERNATIONAL SYMPOSIUM ON POWER SEMICONDUCTOR DEVICES & IC'S (ISPSD) SE Proceedings of the International Symposium on Power Semiconductor Devices & ICs LA English DT Proceedings Paper CT IEEE 26th International Symposium on Power Semiconductor Devices & IC's (ISPSD) CY JUN 15-19, 2014 CL Waikoloa, HI SP IEEE AB Modern power electronics systems try to maximize power density and efficiency. As such, the active switch is required to safely handle very stressful transient conditions. A 56 mm(2), 180 A, SiC DMOSFET manufactured by Cree Inc. is evaluated by electrically stressing the device in a RLC ringdown test system capable of producing peak current in excess of 600 A (> 3X rated current) and di/dt's as high as 860 A/mu s. The device was hard-switched 5,000 times at repetition rates of 1, 2, 5, and 10 Hz for a total of 20,000 switching events. The device characteristics were monitored every 1,000 shots on a high power curve tracer to determine device degradation. The devices showed no changes in blocking characteristics and minimal changes in on-state characteristics due to shifts in the threshold voltage after 20,000 hard switching events. The threshold voltage shifts over the test period are minimal with a +/- 93 mV deviation from the average of 4.39 V. With the stability of the threshold voltage, on-state characteristics, and blocking characteristics; this shows that this device would perform reliably within commercial applications that include stressful switching conditions. C1 [Lawson, K.; Schrock, J.; Ray, W., II; Bayne, S.] Texas Tech Univ, Ctr Pulsed Power & Power Elect, Lubbock, TX 79409 USA. [Cheng, L.; Palmour, J.; Allen, S.] Power Devices Div Cree Inc, Durham, NC USA. US Army Res Lab, Sensors Elect Dev Directorate, Adelphi, MD USA. RP Lawson, K (reprint author), Texas Tech Univ, Ctr Pulsed Power & Power Elect, Lubbock, TX 79409 USA. EM kevin.lawson@ttu.edu FU Cree Inc.; Texas Tech University's Center for Pulsed Power and Power Electronic FX This work was sponsored by Cree Inc. Texas Tech University's Center for Pulsed Power and Power Electronics would like to thank Cree for providing the devices used for testing. NR 13 TC 3 Z9 3 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1063-6854 BN 978-1-4799-2918-4 J9 PROC INT SYMP POWER PY 2014 BP 301 EP 304 PG 4 WC Computer Science, Hardware & Architecture; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BB8JG UT WOS:000346735500074 ER PT S AU Mojab, A Mazumder, SK Cheng, L Agarwal, AK Scozzie, CJ AF Mojab, A. Mazumder, S. K. Cheng, L. Agarwal, A. K. Scozzie, C. J. GP IEEE TI 15-kV Single-Bias All-Optical ETO Thyristor SO 2014 IEEE 26TH INTERNATIONAL SYMPOSIUM ON POWER SEMICONDUCTOR DEVICES & IC'S (ISPSD) SE Proceedings of the International Symposium on Power Semiconductor Devices & ICs LA English DT Proceedings Paper CT IEEE 26th International Symposium on Power Semiconductor Devices & IC's (ISPSD) CY JUN 15-19, 2014 CL Waikoloa, HI SP IEEE ID KV AB A new all-optical emitter-turn-off (ETO) configuration is proposed in this paper which is operated under 15 kV single bias and a current of 10 A. This ETO is completely controlled by two optical signals, one for the 15 kV SiC gate-turn-off (GTO) thyristor and the other one for a triggering low-voltage optically controlled Si switch. The latter, called optically-triggered power transistor (OTPT), is used in series with the anode contact of the SiC GTO thyristor in order to handle the current switching between anode and gate path of the SiC GTO thyristor. This OTPT is triggered with a 5-W laser of 808-nm wavelength and the main SiC GTO thyristor is triggered with a laser having a low wavelength of 266 nm. The voltage drop on the OTPT during the on-state is controlled by the power of the laser. For an optical power of 5 W, the structure is optimized to have an on-state voltage of 0.2 V at the junction temperature of 200 degrees C. This is less than 0.002% of the total bias of 15 kV. C1 [Mojab, A.; Mazumder, S. K.] Univ Illinois Chicago UIC, Lab Energy & Switching Elect Syst, 851 South Morgan St, Chicago, IL 60607 USA. [Cheng, L.] Cree Inc, Durham, NC 27703 USA. [Agarwal, A. K.] US DOE, Washington, DC 20585 USA. [Scozzie, C. J.] US Army Res Lab, Adelphi, MD USA. RP Mojab, A (reprint author), Univ Illinois Chicago UIC, Lab Energy & Switching Elect Syst, 851 South Morgan St, Chicago, IL 60607 USA. EM amojab2@uic.edu; mazumder@uic.edu FU U.S. NSF [1202384]; U.S. ARPA-E [DE-AR0000336]; US Army Research Laboratory in Adelphi, MD FX This work is supported in part by U.S. NSF (award no. 1202384) and U.S. ARPA-E (award no. DE-AR0000336). However, any opinions, findings, conclusions, or recommendations expressed herein are those of the authors and do not necessarily reflect the views of the NSF or ARPA-E. At Cree Inc., this work was supported by C. Scozzie of the US Army Research Laboratory in Adelphi, MD. NR 15 TC 6 Z9 6 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1063-6854 BN 978-1-4799-2918-4 J9 PROC INT SYMP POWER PY 2014 BP 313 EP 316 PG 4 WC Computer Science, Hardware & Architecture; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BB8JG UT WOS:000346735500077 ER PT S AU Rezaei, MA Wang, GY Huang, AQ Cheng, L Scozzie, C AF Rezaei, Mohammad Ali Wang, Gangyao Huang, Alex Q. Cheng, Lin Scozzie, Charles GP IEEE TI Static and Dynamic Characterization of a > 13kV SiC p-ETO Device SO 2014 IEEE 26TH INTERNATIONAL SYMPOSIUM ON POWER SEMICONDUCTOR DEVICES & IC'S (ISPSD) SE Proceedings of the International Symposium on Power Semiconductor Devices & ICs LA English DT Proceedings Paper CT IEEE 26th International Symposium on Power Semiconductor Devices & IC's (ISPSD) CY JUN 15-19, 2014 CL Waikoloa, HI SP IEEE ID TURN-OFF THYRISTOR AB This study addresses the transient and steady-state performance of a >13 kV SiC p-ETO. The developed SiC p-ETO is based on a 1 cm(2), 15 kV SiC p-GTO with an extremely low differential resistance. Static performance of the device, including the on-state voltage drop at different temperatures and different currents is carried out in this paper. Furthermore, transient performance of the device, including the turn off energy and also the Safe Operating Area (SOA) of the device has been studied. Also, the superior performance of the p-type SiC-ETO has been exploited to design and implement a solid-state circuit breaker. The studies verify the superiority of the SiC p-ETO compared to other solid state devices for this application. C1 [Rezaei, Mohammad Ali; Wang, Gangyao; Huang, Alex Q.] North Carolina State Univ, FREEDM Syst Ctr, Raleigh, NC 27695 USA. [Cheng, Lin] CREE Inc, Durham, NC USA. [Scozzie, Charles] US Army Res Lab, Adelphi, MD USA. RP Rezaei, MA (reprint author), North Carolina State Univ, FREEDM Syst Ctr, Raleigh, NC 27695 USA. RI Huang, Alex/Q-9784-2016 OI Huang, Alex/0000-0003-3427-0335 NR 8 TC 5 Z9 5 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1063-6854 BN 978-1-4799-2918-4 J9 PROC INT SYMP POWER PY 2014 BP 354 EP 357 PG 4 WC Computer Science, Hardware & Architecture; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BB8JG UT WOS:000346735500087 ER PT S AU Brunt, EV Cheng, L O'Loughlin, M Capell, C Jonas, C Lam, K Richmond, J Pala, V Ryu, S Allen, ST Burk, AA Palmour, JW AF Brunt, E. V. Cheng, L. O'Loughlin, M. Capell, C. Jonas, C. Lam, K. Richmond, J. Pala, V. Ryu, S. Allen, S. T. Burk, A. A. Palmour, J. W. GP IEEE TI 22 kV, 1 cm(2), 4H-SiC n-IGBTs with Improved Conductivity Modulation SO 2014 IEEE 26TH INTERNATIONAL SYMPOSIUM ON POWER SEMICONDUCTOR DEVICES & IC'S (ISPSD) SE Proceedings of the International Symposium on Power Semiconductor Devices & ICs LA English DT Proceedings Paper CT IEEE 26th International Symposium on Power Semiconductor Devices & IC's (ISPSD) CY JUN 15-19, 2014 CL Waikoloa, HI SP IEEE AB In this paper, we report our recently developed large area 4H-SiC n-IGBTs that have a chip size of 1 cm(2) and an active conducting area of 0.37 cm(2). A blocking voltage of 22.6 kV has been demonstrated with a leakage current of 9 mu A at a gate bias of 0 V at room-temperature. This is the highest breakdown voltage of a single MOS-controlled semiconductor switch reported to date. To improve the conductivity modulation and lower the conduction losses during the on-state, a thermal oxidation process was applied to enhance the carrier lifetime prior to the device fabrication. Compared to the devices that did not receive this lifetime enhancement process, the lifetime enhanced devices displayed nearly 1 V lower forward voltage drop with little increase in switching energy and no degradation of static blocking characteristics. A specific differential on-resistance of 55 m Omega-cm(2) at 20 A and 125 degrees C was achieved, suggesting that bipolar power devices with thick drift regions can benefit from further enhancement of the ambipolar carrier lifetime. C1 [Brunt, E. V.; Cheng, L.; O'Loughlin, M.; Capell, C.; Jonas, C.; Lam, K.; Richmond, J.; Pala, V.; Ryu, S.; Allen, S. T.; Burk, A. A.; Palmour, J. W.] Cree Inc, 4600 Silicon Dr, Durham, NC 27703 USA. US Army Res Lab, Adelphi, MD USA. RP Brunt, EV (reprint author), Cree Inc, 4600 Silicon Dr, Durham, NC 27703 USA. EM edward_vanbrunt@cree.com FU U.S. Army Research Laboratory located at Adelphi, MD, USA FX This work was funded by U.S. Army Research Laboratory located at Adelphi, MD, USA. NR 4 TC 13 Z9 13 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1063-6854 BN 978-1-4799-2918-4 J9 PROC INT SYMP POWER PY 2014 BP 358 EP 361 PG 4 WC Computer Science, Hardware & Architecture; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BB8JG UT WOS:000346735500088 ER PT S AU Cahill, JP Okusaga, O Zhou, WM Menyuk, CR Carter, GM AF Cahill, James P. Okusaga, Olukayode Zhou, Weimin Menyuk, Curtis R. Carter, Gary M. GP IEEE TI Optimization of modulation techniques for suppression of GEMRS in frequency transfer systems SO 2014 IEEE INTERNATIONAL FREQUENCY CONTROL SYMPOSIUM (FCS) SE IEEE International Frequency Control Symposium LA English DT Proceedings Paper CT 1st IEEE International Frequency Control Symposium (FCS) CY MAY 19-22, 2014 CL Taipei, TAIWAN SP IEEE, UFFC, Asia Pacific Metrol Programme, Minist Sci & Technol, NAR Labs, Instrument Technol Res Ctr, Sensors & Actuators Tech, Tsing Hua Univ DE Rayleigh scattering; frequency transfer; RF-photonic links ID RAYLEIGH-SCATTERING; OPTICAL-FIBERS AB Guided entropy mode Rayleigh scattering in optical fibers has been shown to have detrimental effects in optical fiber links for radio frequency transfer, optoelectronic oscillators (OEOs), and broadband analog optical fiber links. We have previously shown that GEMRS-induced noise can be suppressed via sinusoidal dithering of the laser drive current. Previously, we had hypothesized that this suppression is due to the laser frequency modulation it induces. In this work, we show for the first time GEMRS suppression via external phase modulation, thereby confirming that suppression is achieved via the frequency modulation component of the laser current dither. This result provides further evidence that GEMRS is a laser-driven, phase-dependent effect. Additionally, external modulation offers several advantages over the previously demonstrated intra-cavity modulation, including greater bandwidth and improved flexibility in implementation. C1 [Cahill, James P.; Okusaga, Olukayode; Zhou, Weimin] US Army Res Lab, Adelphi, MD USA. [Cahill, James P.; Menyuk, Curtis R.; Carter, Gary M.] Univ MD Baltimore Cty, Dept Comp Sci & Elect Engn, Baltimore, MD USA. RP Cahill, JP (reprint author), US Army Res Lab, Adelphi, MD USA. EM james.p.cahill.ctr@us.army.mil NR 9 TC 0 Z9 0 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1075-6787 BN 978-1-4799-4916-8 J9 P IEEE INT FREQ CONT PY 2014 BP 510 EP 512 PG 3 WC Engineering, Electrical & Electronic; Physics, Applied; Telecommunications SC Engineering; Physics; Telecommunications GA BB8BZ UT WOS:000346295600141 ER PT J AU McClung, JP Gaffney-Stomberg, E Lee, JJ AF McClung, James P. Gaffney-Stomberg, Erin Lee, Jane J. TI Female athletes: A population at risk of vitamin and mineral deficiencies affecting health and performance SO JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY LA English DT Article; Proceedings Paper CT 10th Meeting of the International-Society-for-Trace-Element-Research-in-Humans (ISTERH) CT 10th International Society for Trace Element Research in Humans (ISTERH) CY NOV 18-22, 2013 CY NOV 18-22, 2013 CL Tokyo, JAPAN CL Tokyo, JAPAN SP Int Soc Trace Element Res Humans DE Calcium; Exercise; Female athlete; Iron; Vitamin D ID RANDOMIZED CONTROLLED-TRIALS; STRESS-FRACTURE RISK; IRON STATUS; HEPCIDIN; WOMEN; PREVENTION; NUTRITION; CALCIUM; RECOMMENDATIONS; PREVALENCE AB Adequate vitamin and mineral status is essential for optimal human health and performance. Female athletes could be at risk for vitamin and mineral insufficiency due to inadequate dietary intake, menstruation, and inflammatory responses to heavy physical activity. Recent studies have documented poor iron status and associated declines in both cognitive and physical performance in female athletes. Similarly, insufficient vitamin D and calcium status have been observed in female athletes, and may be associated with injuries, such as stress fracture, which may limit a female athlete's ability to participate in regular physical activity. This review will focus on recent studies detailing the prevalence of poor vitamin and mineral status in female athletes, using iron, vitamin D, and calcium as examples. Factors affecting the dietary requirement for these vitamins and minerals during physical training will be reviewed. Lastly, countermeasures for the prevention of inadequate vitamin and mineral status will be described. Published by Elsevier GmbH. C1 [McClung, James P.; Gaffney-Stomberg, Erin] US Army Res Inst Environm Med, Mil Nutr Div, Natick, MA 01760 USA. [Lee, Jane J.] Univ Texas Austin, Dept Nutr Sci, Austin, TX 78712 USA. RP McClung, JP (reprint author), US Army Res Inst Environm Med, Mil Nutr Div, Natick, MA 01760 USA. EM James.McClung3@us.army.mil FU United States Department of Energy; United States Army Medical Research and Materiel Command (USAMRMC); Postgraduate Research Participation Program at USARIEM FX This work was supported by an appointment to the Postgraduate Research Participation Program at USARIEM administered by the Oak Ridge Institute for Science and Education (ORISE) through an interagency agreement between the United States Department of Energy and the United States Army Medical Research and Materiel Command (USAMRMC). NR 40 TC 8 Z9 9 U1 6 U2 20 PU ELSEVIER GMBH, URBAN & FISCHER VERLAG PI JENA PA OFFICE JENA, P O BOX 100537, 07705 JENA, GERMANY SN 0946-672X J9 J TRACE ELEM MED BIO JI J. Trace Elem. Med. Biol. PY 2014 VL 28 IS 4 SI SI BP 388 EP 392 DI 10.1016/j.jtemb.2014.06.022 PG 5 WC Biochemistry & Molecular Biology; Endocrinology & Metabolism SC Biochemistry & Molecular Biology; Endocrinology & Metabolism GA AX8AW UT WOS:000347133800007 PM 25060302 ER PT S AU Riggan, BS Snyder, WE Wang, XG Feng, J AF Riggan, Benjamin S. Snyder, Wesley E. Wang, Xiaogang Feng, Jing BE Jiang, X Hornegger, J Koch, R TI A Human Factors Study of Graphical Passwords Using Biometrics SO PATTERN RECOGNITION, GCPR 2014 SE Lecture Notes in Computer Science LA English DT Proceedings Paper CT 36th German Conference on Pattern Recognition (GCPR) CY SEP 02-05, 2014 CL Munster, GERMANY SP Cells Mot Cluster Excellence, MVTec Software GmbH, Olympus Soft Imaging Solut GmbH, Univ Munster AB One mode of authentication used in modern computing systems is graphical passwords. Graphical passwords are becoming more popular because touch-sensitive and pen-sensitive technologies are becoming ubiquitous. In this paper, we construct the "BioSketch" database, which is a general database of sketch-based passwords (SkPWs) with pressure information used as a biometric property. The BioSketch database is created so that recognition approaches may be commensurable with the benchmark performances. Using this database, we are also able to study the human-computer interaction (HCI) process for SkPWs. In this paper, we compare a generalized SKS recognition algorithm with the Frechet distance in terms of the intra/inter-class variations and performances. The results show that the SKS-based approach achieves as much as a 7% and 17% reduction in equal error rate (EER) for random and skilled forgeries respectively. C1 [Riggan, Benjamin S.; Snyder, Wesley E.; Feng, Jing] North Carolina State Univ, Raleigh, NC 27695 USA. [Wang, Xiaogang] US Army Res Off, Durham, NC USA. RP Riggan, BS (reprint author), North Carolina State Univ, Raleigh, NC 27695 USA. EM bsriggan@ncsu.edu; wes@ncsu.edu; cliff.x.wang.civ@mail.mil; jing_feng@ncsu.edu FU United States Army Research Office ( ARO) [W911NF- 04- D- 0003- 0019] FX The information in this paper is based on work partially funded by the United States Army Research Office ( ARO) grant W911NF- 04- D- 0003- 0019. NR 17 TC 0 Z9 0 U1 0 U2 1 PU SPRINGER INT PUBLISHING AG PI CHAM PA GEWERBESTRASSE 11, CHAM, CH-6330, SWITZERLAND SN 0302-9743 BN 978-3-319-11752-2; 978-3-319-11751-5 J9 LECT NOTES COMPUT SC PY 2014 VL 8753 BP 464 EP 475 DI 10.1007/978-3-319-11752-2_38 PG 12 WC Computer Science, Artificial Intelligence; Computer Science, Theory & Methods; Imaging Science & Photographic Technology SC Computer Science; Imaging Science & Photographic Technology GA BB8OA UT WOS:000347032100038 ER PT J AU Paterson, R Drake, B Tabin, G Butler, FK Cushing, T AF Paterson, Ryan Drake, Brandy Tabin, Geoffrey Butler, Frank K., Jr. Cushing, Tracy TI Wilderness Medical Society Practice Guidelines for Treatment of Eye Injuries and Illnesses in the Wilderness: 2014 Update SO WILDERNESS & ENVIRONMENTAL MEDICINE LA English DT Article ID ACUTE BACTERIAL CONJUNCTIVITIS; HIGH-ALTITUDE; REFRACTIVE SURGERY; TRAUMATIC HYPHEMA; CORNEAL THICKNESS; RED EYE; MANAGEMENT; MOUNTAINEERS; ANTIBIOTICS; HEMORRHAGE AB A panel convened to develop an evidence-based set of guidelines for the recognition and treatment of eye injuries and illnesses that may occur in the wilderness. These guidelines are meant to serve as a tool to help wilderness providers accurately identify and subsequently treat or evacuate for a variety of ophthalmologic complaints. Recommendations are graded on the basis of the quality of their supporting evidence and the balance between risks and benefits according to criteria developed by the American College of Chest Physicians. This is an updated version of the original guidelines published in Wilderness & Environmental Medicine 2012;23(4):325-336. C1 [Drake, Brandy] Valley View Hosp, Glenwood Springs, CO USA. [Paterson, Ryan; Cushing, Tracy] Univ Colorado, Denver Hlth Med Ctr, Sch Med, Denver, CO USA. [Tabin, Geoffrey] Univ Utah, Sch Med, Salt Lake City, UT USA. [Butler, Frank K., Jr.] US Army Inst Surg Res, Comm Tact Combat Casualty Care, Def Board, Ft Sam Houston, TX USA. RP Paterson, R (reprint author), Univ Colorado, Sch Med, Denver Hlth Med Ctr, 1835 Franldin St, Denver, CO 80218 USA. EM ryampaterson@ucdenver.edu NR 61 TC 0 Z9 0 U1 1 U2 1 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 1080-6032 EI 1545-1534 J9 WILD ENVIRON MED JI Wildern. Environ. Med. PY 2014 VL 25 IS 4 SU S SI SI BP S19 EP S29 DI 10.1016/j.wem.2014.08.008 PG 11 WC Public, Environmental & Occupational Health; Sport Sciences SC Public, Environmental & Occupational Health; Sport Sciences GA AX5EJ UT WOS:000346949400004 PM 25498259 ER PT J AU Ramirez, A Arce, GR Sadler, BM AF Ramirez, Ana Arce, Gonzalo R. Sadler, Brian M. GP IEEE TI Spectral Image Unmixing From Optimal Coded-Aperture Compressive Measurements SO 2014 6TH INTERNATIONAL SYMPOSIUM ON COMMUNICATIONS, CONTROL AND SIGNAL PROCESSING (ISCCSP) LA English DT Proceedings Paper CT 6th International Symposium on Communications, Control and Signal Processing (ISCCSP) CY MAY 21-23, 2014 CL Athens, GREECE SP IEEE, IEEE Circuits & Syst Soc, IEEE Control Syst Soc, IEEE Signal Proc Soc, Univ Patras DE CASSI; coded aperture; spectral unmixing; hyperspectral imagery; sparsity ID DESIGN AB Hyperspectral remote sensing often captures imagery where the spectral profiles of the spatial pixels are the result of the reflectance contribution of numerous materials. Spectral unmixing is then used to extract the collection of materials, or endmembers, contained in the measured spectra, and a set of corresponding fractions that indicate the abundance of each material present at each pixel. This work aims at developing a spectral unmixing algorithm directly from compressive measurements acquired using the coded-aperture snapshot spectral imaging (CASSI) system. The proposed method first uses the compressive measurements to find a sparse vector representation of each pixel in a 3-D dictionary formed by a 2-D wavelet basis and a known spectral library of endmembers. The sparse vector representation is estimated by solving a sparsity-constrained optimization problem using an algorithm based on the variable splitting augmented Lagrangian multipliers method. The performance of the proposed spectral unmixing method is improved by taking optimal CASSI compressive measurements obtained when optimal coded apertures are used in the optical system. The optimal coded apertures are designed such that the CASSI sensing matrix satisfies a Restricted Isometry Property (RIP) with high probability. Simulations with synthetic hyperspectral cubes illustrate the accuracy of the proposed unmixing method. C1 [Ramirez, Ana; Arce, Gonzalo R.] Univ Delaware, Dept Elect & Comp Engn, Newark, DE 19716 USA. [Sadler, Brian M.] US Army Res Lab, Adelphi, MD 20783 USA. RP Ramirez, A (reprint author), Univ Delaware, Dept Elect & Comp Engn, Newark, DE 19716 USA. FU Army Research Laboratory; Army Research Office [W911NF-11-1-0368]; National Science Foundation [CCF-0915800] FX This work was supported in part by the Army Research Laboratory and the Army Research Office under the grant W911NF-11-1-0368, and by the National Science Foundation under Grant CCF-0915800. NR 16 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-2890-3 PY 2014 BP 230 EP 233 PG 4 WC Automation & Control Systems; Engineering, Electrical & Electronic SC Automation & Control Systems; Engineering GA BB8DS UT WOS:000346443500057 ER PT S AU Rodak, LE Sampath, AV Chen, Y Zhou, Q Campbell, JC Shen, H Wraback, M AF Rodak, L. E. Sampath, A. V. Chen, Y. Zhou, Q. Campbell, J. C. Shen, H. Wraback, M. GP IEEE TI Enhancing the Deep Ultraviolet Response of 4H-Silicon Carbide-based Photodiodes between 210 nm and 255 nm SO 2014 72ND ANNUAL DEVICE RESEARCH CONFERENCE (DRC) SE IEEE Device Research Conference Proceedings LA English DT Proceedings Paper CT 72nd Annual Device Research Conference (DRC) CY JUN 22-25, 2014 CL Univ Calif, Santa Barbara, CA SP IEEE, IEEE Electron Devices Soc HO Univ Calif ID 4H-SIC AVALANCHE PHOTODIODES C1 [Rodak, L. E.; Sampath, A. V.; Shen, H.; Wraback, M.] US Army Res Lab, RDRL SEE M, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. [Chen, Y.; Zhou, Q.; Campbell, J. C.] Univ Virginia, Charlottesville, VA 22903 USA. RP Rodak, LE (reprint author), US Army Res Lab, RDRL SEE M, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 2 TC 0 Z9 0 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1548-3770 BN 978-1-4799-5406-3 J9 IEEE DEVICE RES CONF PY 2014 BP 95 EP + PG 2 WC Engineering, Electrical & Electronic SC Engineering GA BB8CE UT WOS:000346309800041 ER PT S AU Price, S Donohoe, JP Fairley, JR AF Price, Steven Donohoe, J. Patrick Fairley, Josh R. GP IEEE TI Effects of Wall Moisture Profiles on Matched Illumination Waveforms - Simulation and Measurement SO 2014 IEEE RADAR CONFERENCE SE IEEE Radar Conference LA English DT Proceedings Paper CT IEEE Radar Conference - From Sensing to Information CY MAY 19-23, 2014 CL Cincinnati, OH SP IEEE, AESS, IEEE Signal Proc Soc, IEEE Geoscience & Remote Sensing Soc, IEEE Antennas & Propagat Soc, Antenna Measurement & Tech Assoc, Inst Navigat ID RADAR; DESIGN AB The effects of wall moisture on the characteristics of matched illumination waveforms for use in through the wall radar imaging (TWRI) are examined via simulation. Various wall moisture profiles are considered for solid adobe-like walls including a uniform moisture profile, moisture concentrated in the interior region of the wall, and moisture concentrated at the exterior surface. Specific characteristics of the typical optimum waveform are noted for each of the moisture profiles considered. Techniques for experimentally validating the performance of the matched illumination waveforms are also summarized. C1 [Price, Steven; Donohoe, J. Patrick] Mississippi State Univ, Mississippi State, MS 39762 USA. [Fairley, Josh R.] US Army, Coastal Engn Res & Dev Ctr, Geotec & Structure Lab, Vicksburg, MS 39180 USA. RP Price, S (reprint author), Mississippi State Univ, Mississippi State, MS 39762 USA. EM sp391@msstate.edu; donohoe@ece.msstate.edu; Josh.Fairley@usace.army.mil NR 16 TC 2 Z9 2 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1097-5764 BN 978-1-4799-2035-8 J9 IEEE RAD CONF PY 2014 BP 597 EP 601 PG 5 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA BB8EZ UT WOS:000346494600118 ER PT S AU Jokanovic, B Amin, MG Dogaru, T AF Jokanovic, Branka Amin, Moeness G. Dogaru, Traian GP IEEE TI Interpolation and Sparse Reconstrunctions of Doppler and MicroDoppler Signatures under Missing Samples SO 2014 IEEE RADAR CONFERENCE SE IEEE Radar Conference LA English DT Proceedings Paper CT IEEE Radar Conference - From Sensing to Information CY MAY 19-23, 2014 CL Cincinnati, OH SP IEEE, AESS, IEEE Signal Proc Soc, IEEE Geoscience & Remote Sensing Soc, IEEE Antennas & Propagat Soc, Antenna Measurement & Tech Assoc, Inst Navigat DE interpolation; time-frequency distribution; sparse reconstruction AB The paper considers Doppler and microDoppler radar signature estimations in the presence of missing samples using time-frequency distributions. Incomplete or random sampled data can be due to ranging and localization enhancements, discarding noisy measurements, hardware simplification, sampling rate limitations, or logistical restrictions on data collections and acquisition. We demonstrate that the use of interpolators to estimate the missing samples in the instantaneous autocorrelation function outperforms time-domain data interpolations. We compare time-frequency distributions with and without data interpolations and contrast their performance with sparse signal reconstruction which exploits the sparsity of the Doppler signature in the time-frequency domain. C1 [Jokanovic, Branka; Amin, Moeness G.] Villanova Univ, Ctr Adv Commun, Villanova, PA 19085 USA. [Dogaru, Traian] US Army Res Lab, Adelphi, MD 20783 USA. RP Jokanovic, B (reprint author), Villanova Univ, Ctr Adv Commun, Villanova, PA 19085 USA. FU ARO; ARL [W911NF-11-10536] FX This work is supported by ARO and ARL under contract W911NF-11-10536. NR 23 TC 1 Z9 1 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1097-5764 BN 978-1-4799-2035-8 J9 IEEE RAD CONF PY 2014 BP 912 EP 917 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA BB8EZ UT WOS:000346494600178 ER PT S AU Gallagher, KA Narayanan, RM Mazzaro, GJ Sherbondy, KD AF Gallagher, Kyle A. Narayanan, Ram M. Mazzaro, Gregory J. Sherbondy, Kelly D. GP IEEE TI Linearization of a Harmonic Radar Transmitter by Feed-Forward Filter Reflection SO 2014 IEEE RADAR CONFERENCE SE IEEE Radar Conference LA English DT Proceedings Paper CT IEEE Radar Conference - From Sensing to Information CY MAY 19-23, 2014 CL Cincinnati, OH SP IEEE, AESS, IEEE Signal Proc Soc, IEEE Geoscience & Remote Sensing Soc, IEEE Antennas & Propagat Soc, Antenna Measurement & Tech Assoc, Inst Navigat ID INSECT TRACKING; TAGS AB In order to generate a detectable harmonic-radar response from an electronic device, the required power-on-target is comparable to that observed directly below a cellular base station. Also, the signal emitted from the target is often very weak. This weak signal must not be masked by harmonics generated by the radar itself. Thus, high transmit power must be provided with high linearity for detection of a nonlinear-radar target. In this paper, a technique is presented which achieves better than 135 dBc harmonic distortion at 7 W output power, at transmit frequencies between 800 MHz and 1 GHz. C1 [Gallagher, Kyle A.; Narayanan, Ram M.] Penn State Univ, Dept Elect Engn, University Pk, PA 16802 USA. [Mazzaro, Gregory J.] Citadel, Charleston, SC 29409 USA. [Sherbondy, Kelly D.] U S Army Res Lab, Sensors & Elect Devices Directorate, Adelphi, MD 20783 USA. RP Gallagher, KA (reprint author), Penn State Univ, Dept Elect Engn, University Pk, PA 16802 USA. OI Sherbondy, Kelly/0000-0003-4730-3706 FU US Army Research Office and Army Research Laboratory through Delaware State University [W911NF-11-2-0046] FX The research presented in this paper is supported by the US Army Research Office and Army Research Laboratory Grant # W911NF-11-2-0046 through a subcontract from Delaware State University. NR 22 TC 3 Z9 3 U1 0 U2 4 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1097-5764 BN 978-1-4799-2035-8 J9 IEEE RAD CONF PY 2014 BP 1363 EP 1368 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA BB8EZ UT WOS:000346494600269 ER PT J AU Rao, P Tamboli, P Fillman, EP Meis, JM AF Rao, Priya Tamboli, Pheroze Fillman, Eric P. Meis, Jeanne M. TI Primary intra-renal desmoplastic small round cell tumor: Expanding the histologic spectrum, with special emphasis on the differential diagnostic considerations SO PATHOLOGY RESEARCH AND PRACTICE LA English DT Article DE Desmoplastic small round cell tumor; Kidney; Renal primary; FISH; PCR ID KIDNEY; SARCOMA; UTILITY; FUSION AB Intra-abdominal desmoplastic small round cell tumor (DSRCT) is a rare, aggressive tumor affecting adolescent and young males. DSRCT presenting as a primary renal mass in the absence of visceral or serosal involvement is extremely rare. Herein, we present the pathologic and molecular findings in the case of a young man who presented with a large renal mass without any visceral or serosal involvement. Noticeably, the tumor lacked prominent desmoplastic stroma and only focally expressed cytokeratin, both of which are considered characteristic histologic features for this tumor. Fluorescence in situ hybridization studies using an EWSR1 break-apart probe confirmed the presence of a rearrangement involving the EWSR1 locus and RT-PCR demonstrated the presence of an EWSR1-WT1 fusion transcript associated with the t(11;22) rearrangement, which supported a diagnosis of DSRCT. We also discuss the differential diagnostic considerations faced by the pathologist in the workup of small round cell neoplasms of the kidney. (C) 2014 Elsevier GmbH. All rights reserved. C1 [Rao, Priya; Tamboli, Pheroze; Meis, Jeanne M.] Univ Texas Houston, MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA. [Fillman, Eric P.] Brooke Army Med Ctr, Dept Pathol, Ft Sam Houston, TX 78234 USA. RP Rao, P (reprint author), Univ Texas Houston, MD Anderson Canc Ctr, Dept Pathol, 1515 Holcombe Blvd,Unit 085, Houston, TX 77030 USA. EM prao@mdanderson.org OI Rao, Priya/0000-0001-5672-0961 NR 15 TC 3 Z9 3 U1 0 U2 0 PU ELSEVIER GMBH, URBAN & FISCHER VERLAG PI JENA PA OFFICE JENA, P O BOX 100537, 07705 JENA, GERMANY SN 0344-0338 J9 PATHOL RES PRACT JI Pathol. Res. Pract. PY 2014 VL 210 IS 12 BP 1130 EP 1133 DI 10.1016/j.prp.2014.05.013 PG 4 WC Pathology SC Pathology GA AW7OT UT WOS:000346454200056 PM 24953786 ER PT J AU Teyhen, D Bergeron, MF Deuster, P Baumgartner, N Beutler, AI de la Motte, SJ Jones, BH Lisman, P Padua, DA Pendergrass, TL Pyne, SW Schoomaker, E Sell, TC O'Connor, F AF Teyhen, Deydre Bergeron, Michael F. Deuster, Patricia Baumgartner, Neal Beutler, Anthony I. de la Motte, Sarah J. Jones, Bruce H. Lisman, Peter Padua, Darin A. Pendergrass, Timothy L. Pyne, Scott W. Schoomaker, Eric Sell, Timothy C. O'Connor, Francis TI Consortium for Health and Military Performance and American College of Sports Medicine Summit: Utility of Functional Movement Assessment in Identifying Musculoskeletal Injury Risk SO CURRENT SPORTS MEDICINE REPORTS LA English DT Review ID CRUCIATE LIGAMENT INJURY; LOWER-EXTREMITY INJURY; RANDOMIZED-CONTROLLED-TRIAL; TIBIAL STRESS-FRACTURE; PATELLOFEMORAL PAIN SYNDROME; CHRONIC ANKLE INSTABILITY; DYNAMIC POSTURAL CONTROL; EXCURSION BALANCE TEST; DECREASING LANDING FORCES; CLINICAL-ASSESSMENT TOOL AB Prevention of musculoskeletal injuries (MSKI) is critical in both civilian and military populations to enhance physical performance, optimize health, and minimize health care expenses. Developing a more unified approach through addressing identified movement impairments could result in improved dynamic balance, trunk stability, and functional movement quality while potentially minimizing the risk of incurring such injuries. Although the evidence supporting the utility of injury prediction and return-to-activity readiness screening tools is encouraging, considerable additional research is needed regarding improving sensitivity, specificity, and outcomes, and especially the implementation challenges and barriers in a military setting. If selected current functional movement assessments can be administered in an efficient and cost-effective manner, utilization of the existing tools may be a beneficial first step in decreasing the burden of MSKI, with a subsequent focus on secondary and tertiary prevention via further assessments on those with prior injury history. C1 [Teyhen, Deydre] US Army Baylor Univ, Ft Sam Houston, TX 78234 USA. [Bergeron, Michael F.] Sanford USD Sch Med, Dept Pediat, Natl Youth Sports Hlth & Safety Inst, Sioux Falls, SD USA. [Deuster, Patricia; O'Connor, Francis] Uniformed Serv Univ Hlth Sci, Consortium Hlth & Mil Performance, Dept Mil & Emergency Med, Bethesda, MD 20814 USA. [Baumgartner, Neal] Randolph Air Force Base, Headquarters Air Educ & Training Command, Randolph, TX USA. [Beutler, Anthony I.; de la Motte, Sarah J.; Lisman, Peter] Uniformed Serv Univ Hlth Sci, Dept Family Med, Bethesda, MD USA. [Jones, Bruce H.] US Army Publ Hlth Command, Army Inst Publ Hlth, Aberdeen Proving Ground, MD USA. [Lisman, Peter] Towson Univ, Dept Kinesiol, Towson, MD USA. [Padua, Darin A.] Univ N Carolina, Dept Exercise & Sport Sci, Chapel Hill, NC USA. [Pendergrass, Timothy L.] US Army Med Command, Off Surg Gen, Falls Church, VA USA. [Pyne, Scott W.] US Naval Acad, Team Phys, Annapolis, MD 21402 USA. [Schoomaker, Eric] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA. [Sell, Timothy C.] Univ Pittsburgh, Sch Hlth & Rehabil Sci, Dept Sports Med & Nutr, Pittsburgh, PA USA. RP Teyhen, D (reprint author), US Army Baylor Univ, 3151 Scott Rd, Ft Sam Houston, TX 78234 USA. EM deydre.s.teyhen.mil@mail.mil RI Deuster, Patricia/G-3838-2015 OI Deuster, Patricia/0000-0002-7895-0888 NR 168 TC 10 Z9 10 U1 2 U2 14 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 1537-890X EI 1537-8918 J9 CURR SPORT MED REP JI Curr. Sport. Med. Rep. PD JAN-FEB PY 2014 VL 13 IS 1 BP 52 EP 63 DI 10.1249/JSR.0000000000000023 PG 12 WC Sport Sciences SC Sport Sciences GA AW6TC UT WOS:000346400200012 PM 24412892 ER PT J AU Han, SD Borodin, O Seo, DM Zhou, ZB Henderson, WA AF Han, Sang-Don Borodin, Oleg Seo, Daniel M. Zhou, Zhi-Bin Henderson, Wesley A. TI Electrolyte Solvation and Ionic Association V. Acetonitrile-Lithium Bis(fluorosulfonyl)imide (LiFSI) Mixtures SO JOURNAL OF THE ELECTROCHEMICAL SOCIETY LA English DT Article ID LIQUID ELECTROLYTE; ELECTROCHEMICAL PROPERTIES; MOLECULAR-DYNAMICS; CRYSTAL-STRUCTURE; PHASE-TRANSITION; ROOM-TEMPERATURE; SUPERCONCENTRATED ELECTROLYTES; PHYSICOCHEMICAL PROPERTIES; GRAPHITE-ELECTRODES; POWDER DIFFRACTION AB Electrolytes with the salt lithium bis(fluorosulfonyl)imide (LiFSI) have been evaluated relative to comparable electrolytes with other lithium salts. Acetonitrile (AN) has been used as a model electrolyte solvent due to the simplicity of its solvation interactions (the AN molecule has only a single electron lone-pair for Li+ cation coordination). The information obtained from the thermal phase behavior, solvation/ionic association interactions, quantum chemical (QC) calculations and molecular dynamics (MD) simulations (with an APPLE&P many-body polarizable force field for the LiFSI salt) of the (AN)(n)-LiFSI mixtures provides detailed insight into the coordination interactions of the FSI-anions and the wide variability noted in the electrolyte transport properties (i.e., viscosity and ionic conductivity). (C) The Author(s) 2014. Published by ECS. All rights reserved. C1 [Han, Sang-Don; Seo, Daniel M.; Henderson, Wesley A.] N Carolina State Univ, Dept Chem & Biomol Engn, ILEET Lab, Raleigh, NC 27695 USA. [Borodin, Oleg] US Army Res Lab, Sensor & Electron Devices Directorate, Electrochem Branch, Adelphi, MD 20783 USA. [Zhou, Zhi-Bin] Huazhong Univ Sci & Technol, Wuhan 430074, Peoples R China. [Henderson, Wesley A.] Pacific NW Natl Lab, Energy & Environm Directorate, Electrochem Mat & Syst Grp, Richland, WA 99352 USA. RP Han, SD (reprint author), N Carolina State Univ, Dept Chem & Biomol Engn, ILEET Lab, Raleigh, NC 27695 USA. EM oleg.a.borodin.civ@mail.mil; Wesley.Henderson@pnnl.gov RI Borodin, Oleg/B-6855-2012 OI Borodin, Oleg/0000-0002-9428-5291 FU U.S. Department of Energy Batteries for Advanced Transportation Technologies (BATT) Program [DE-AC02-05-CH11231] FX The authors wish to express their gratitude to the U.S. Department of Energy Batteries for Advanced Transportation Technologies (BATT) Program which fully supported the experimental research under Award Number DE-AC02-05-CH11231. NR 87 TC 15 Z9 15 U1 8 U2 48 PU ELECTROCHEMICAL SOC INC PI PENNINGTON PA 65 SOUTH MAIN STREET, PENNINGTON, NJ 08534 USA SN 0013-4651 EI 1945-7111 J9 J ELECTROCHEM SOC JI J. Electrochem. Soc. PY 2014 VL 161 IS 14 BP A2042 EP A2053 DI 10.1149/2.0101414jes PG 12 WC Electrochemistry; Materials Science, Coatings & Films SC Electrochemistry; Materials Science GA AW0IO UT WOS:000345975500017 ER PT S AU Wu, CC Weingarten, NS Chung, PW AF Wu, Chi-Chin Weingarten, N. Scott Chung, Peter W. BE Eddy, CR Kuball, M Koleske, DD Amano, H TI Cross slip of dislocation loops in GaN under shear SO PHYSICA STATUS SOLIDI C: CURRENT TOPICS IN SOLID STATE PHYSICS, VOL 11, NO 3-4 SE Physica Status Solidi C-Current Topics in Solid State Physics LA English DT Proceedings Paper CT 10th International Conference on Nitride Semiconductors (ICNS) CY AUG 25-30, 2013 CL Washington, DC SP Off Naval Res, Army Res Off, Sandia Natl Lab, Natl Sci Fdn, Zeiss, Nichia, Laytec, Nitride Semicond Fdn Japan, Aixtron, Osram, Plasma Therm, Crystal IS, Dow Elect Mat DE dislocation loops; GaN; shear ID MOLECULAR-DYNAMICS; THIN-FILMS; BULK ALN; CRYSTAL; GROWTH; RELAXATION; NITRIDE; EPITAXY AB This work explores possible cross-slip mechanisms of gliding type = a/3[1 -2 1 0] dislocation loops in wurtzite gallium nitride (GaN) as a function of slip plane. A modified form of the dislocation dynamics code Para-DiS was employed using isotropic linear elasticity and dislocation mobilities estimated in part from molecular dynamics (MD) simulations. Under an externally applied uniform stress, the occurrence of cross slip events is highly dependent on the initial dislocation slip plane. The basal plane is the preferred active plane, owing to the greater mobility of type segments on that plane, over the other planes considered including the prismatic (-1 0 1 0) and two equivalent pyramidal planes (-1 0 1 1) and (1 0 -1 1). For an applied stress state, cross slip processes are more readily seen from the prismatic-to-basal planes or the pyramidal-to-basal planes, and neither is found to occur in reverse. Cross slip by climb is not presently considered. In all cases, cross-slip events occur after the loop expands until a greater number of screw-oriented segments are able to access the cross slip plane and the resolved stresses on the plane become sufficiently large. In comparison to dislocations found in GaN previously, the calculations suggest that some threading dislocations along the [0001] direction that have edge character may have been formed from loops whose screw segments slip and escape on basal planes leaving only the edge segments. (C) 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim C1 [Wu, Chi-Chin; Chung, Peter W.] US Army, Computat & Informat Sci Directorate, Res Lab, Aberdeen Proving Ground, MD 21005 USA. [Weingarten, N. Scott] US Army, Res Lab, Weapons & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. [Chung, Peter W.] Univ Maryland, Dept Mech Engn, College Pk, MD 20742 USA. RP Wu, CC (reprint author), US Army, Computat & Informat Sci Directorate, Res Lab, Aberdeen Proving Ground, MD 21005 USA. EM chi-chin.wu.ctr@mail.mil FU DoD High Performance Supercomputing Resources Center ( DSRC); Oak Ridge Affiliated Universities in Maryland [W911QX-04-C-0129]; US Army Research Laboratory ( ARL) [N65235-06-D8847]; ARL Entreprise for Multi-scale Research of Materials FX The computer resources for this work were provided by the DoD High Performance Supercomputing Resources Center ( DSRC). The authors gratefully appreciate the financial support from the Oak Ridge Affiliated Universities in Maryland ( Contract No. W911QX-04-C-0129) and the Secure Mission Solutions at the US Army Research Laboratory ( ARL), ( Contract No. N65235-06-D8847), and the ARL Entreprise for Multi-scale Research of Materials. Valuable discussions with Sylvie Aubry at LLNL, Ramon Collazo at NC-State, and Joshua Crone and Lynn Munday at ARL are also gratefully appreciated. NR 28 TC 1 Z9 1 U1 1 U2 8 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA PAPPELALLEE 3, W-69469 WEINHEIM, GERMANY SN 1862-6351 J9 PHYS STATUS SOLIDI C PY 2014 VL 11 IS 3-4 BP 432 EP 436 DI 10.1002/pssc.201300546 PG 5 WC Nanoscience & Nanotechnology; Physics, Applied; Physics, Condensed Matter SC Science & Technology - Other Topics; Physics GA BB7WP UT WOS:000346071300016 ER PT S AU Connelly, BC Gallinat, CS Woodward, NT Enck, RW Metcalfe, GD Tompkins, R Jones, KA Shen, HG Wraback, M AF Connelly, Blair C. Gallinat, Chad S. Woodward, Nathaniel T. Enck, Ryan W. Metcalfe, Grace D. Tompkins, Randy Jones, Kenneth A. Shen, Hongen Wraback, Michael BE Eddy, CR Kuball, M Koleske, DD Amano, H TI Time-resolved electroabsorption measurement of carrier velocity in inverted polarity In1-xGaxN/GaN heterostructures due to internal electric fields SO PHYSICA STATUS SOLIDI C: CURRENT TOPICS IN SOLID STATE PHYSICS, VOL 11, NO 3-4 SE Physica Status Solidi C-Current Topics in Solid State Physics LA English DT Proceedings Paper CT 10th International Conference on Nitride Semiconductors (ICNS) CY AUG 25-30, 2013 CL Washington, DC SP Off Naval Res, Army Res Off, Sandia Natl Lab, Natl Sci Fdn, Zeiss, Nichia, Laytec, Nitride Semicond Fdn Japan, Aixtron, Osram, Plasma Therm, Crystal IS, Dow Elect Mat DE In1-xGaxN; carrier velocity; internal electric fields; electroabsorption ID N SOLAR-CELLS; STEADY-STATE; GAN; TRANSPORT; POLARIZATION; NITRIDE AB Carrier transport measurements were made in a c-plane inverted-polarity n-GaN/i-In1-xGaxN/p-GaN heterostructure with a 200-nm thick In1-xGaxN layer using ultrafast spectroscopy techniques. Time-domain THz measurements indicate that the direction of electron transport is dominated by drift towards the n-GaN layer. Time-resolved electroabsorption measurements were used to determine carrier velocities by monitoring the change in transmission of a probe beam tuned to the In1-xGaxN absorption edge due to the transport of photogenerated carriers under the built-in internal electric field. Carrier transit times associated with screening of the electroabsorption are resolved at the lowest injection level. The signal rise time shows two distinct time scales, which correspond to an electron velocity of 3.3 +/- 0.5 x 10(7) cm/s and a hole velocity of 6.7 +/- 0.3 x 10(6) cm/s in an internal electric field of similar to 150 kV/cm. (C) 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim C1 [Connelly, Blair C.; Gallinat, Chad S.; Woodward, Nathaniel T.; Enck, Ryan W.; Metcalfe, Grace D.; Tompkins, Randy; Jones, Kenneth A.; Shen, Hongen; Wraback, Michael] US Army Res Lab, Adelphi, MD 20783 USA. RP Connelly, BC (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM blair.connelly.ctr@mail.mil NR 17 TC 1 Z9 1 U1 0 U2 3 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA PAPPELALLEE 3, W-69469 WEINHEIM, GERMANY SN 1862-6351 J9 PHYS STATUS SOLIDI C PY 2014 VL 11 IS 3-4 BP 682 EP 685 DI 10.1002/pssc.201300681 PG 4 WC Nanoscience & Nanotechnology; Physics, Applied; Physics, Condensed Matter SC Science & Technology - Other Topics; Physics GA BB7WP UT WOS:000346071300077 ER PT S AU Woodward, N Enck, R Gallinat, CS Rodak, LE Metcalfe, GD Speck, JS Shen, HG Wraback, M AF Woodward, Nathaniel Enck, Ryan Gallinat, Chad S. Rodak, Lee E. Metcalfe, Grace D. Speck, James S. Shen, Hongen Wraback, Michael BE Eddy, CR Kuball, M Koleske, DD Amano, H TI Evidence of lateral electric fields in c-plane III-V nitrides via terahertz emission SO PHYSICA STATUS SOLIDI C: CURRENT TOPICS IN SOLID STATE PHYSICS, VOL 11, NO 3-4 SE Physica Status Solidi C-Current Topics in Solid State Physics LA English DT Proceedings Paper CT 10th International Conference on Nitride Semiconductors (ICNS) CY AUG 25-30, 2013 CL Washington, DC SP Off Naval Res, Army Res Off, Sandia Natl Lab, Natl Sci Fdn, Zeiss, Nichia, Laytec, Nitride Semicond Fdn Japan, Aixtron, Osram, Plasma Therm, Crystal IS, Dow Elect Mat DE nitride semiconductors; terahertz emission spectroscopy ID PIEZOELECTRIC POLARIZATION AB We observe terahertz (THz) emission from c-plane InN and In0.15Ga0.85N films on GaN templates due to surface-normal transport with a strong anomalous in-plane transport component. Analysis of the rotational dependence of the THz emission associated with this in-plane transport indicates that an electric field exists along the [1-100] m-axis correlated with the underlying template miscut. Calculations show that the field is correlated with strain-induced polarization fields at the heterointerface related to step-like charges at interfaces of the epilayers and the miscut templates. (C) 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim C1 [Woodward, Nathaniel; Enck, Ryan; Gallinat, Chad S.; Rodak, Lee E.; Metcalfe, Grace D.; Shen, Hongen; Wraback, Michael] US Army Res Lab, Sensors & Elect Devices Directorate, RDRL SEE M, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. [Speck, James S.] Univ Calif, Dept Mat, Santa Barbara, CA 93106 USA. RP Woodward, N (reprint author), US Army Res Lab, Sensors & Elect Devices Directorate, RDRL SEE M, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM Nathaniel.woodward2.ctr@mail.mil FU U.S.Army Research Laboratory Postdoctoral Fellowship Program FX N.T.Woodward and C.Gallinat gratefully acknowledge support from the U.S.Army Research Laboratory Postdoctoral Fellowship Program administered by the Oak Ridge Associated Universities through a contract with the U.S.Army Research Laboratory. NR 10 TC 0 Z9 0 U1 0 U2 3 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA PAPPELALLEE 3, W-69469 WEINHEIM, GERMANY SN 1862-6351 J9 PHYS STATUS SOLIDI C PY 2014 VL 11 IS 3-4 BP 686 EP 689 DI 10.1002/pssc.201300687 PG 4 WC Nanoscience & Nanotechnology; Physics, Applied; Physics, Condensed Matter SC Science & Technology - Other Topics; Physics GA BB7WP UT WOS:000346071300078 ER PT S AU Rodak, LE Sampath, AV Gallinat, CS Smith, J Chen, Y Zhou, Q Campbell, JC Shen, H Wraback, M AF Rodak, L. E. Sampath, A. V. Gallinat, C. S. Smith, J. Chen, Y. Zhou, Q. Campbell, J. C. Shen, H. Wraback, M. BE Eddy, CR Kuball, M Koleske, DD Amano, H TI A III-nitride polarization enhanced electron filter for controlling the spectral response of solar-blind AlGaN/AlN/SiC photodiodes SO PHYSICA STATUS SOLIDI C: CURRENT TOPICS IN SOLID STATE PHYSICS, VOL 11, NO 3-4 SE Physica Status Solidi C-Current Topics in Solid State Physics LA English DT Proceedings Paper CT 10th International Conference on Nitride Semiconductors (ICNS) CY AUG 25-30, 2013 CL Washington, DC SP Off Naval Res, Army Res Off, Sandia Natl Lab, Natl Sci Fdn, Zeiss, Nichia, Laytec, Nitride Semicond Fdn Japan, Aixtron, Osram, Plasma Therm, Crystal IS, Dow Elect Mat DE photodiodes; aluminium gallium nitride; silicon carbide; ultraviolet ID 4H-SIC AVALANCHE PHOTODIODES AB Heterogeneous aluminium gallium nitride (AlxGa1-xN)/aluminium nitride (AlN)/silicon carbide (SiC) based n-i-p photodetectors have been demonstrated to effectively tailor the spectral response of SiC within the solar-blind regime. The differences in polarization at the hetero-interfaces resulting in negative polarization induced charge at the AlxGa1-xN/AlN interface and positive polarization induced charge at the AlN/SiC interface has been exploited to create a large barrier to carrier transport across the interface. This barrier impedes the collection of photo-excited holes in the AlxGa1-xN layers and enables the selective collection of electrons photo-excited to the G and L conduction band valleys of SiC while blocking the collection of electrons in the M valley. In this work, the influence of device design, including the AlN layer thickness and AlxGa1-xN composition, on the spectral response is discussed. Thin AlN barrier layers are easily overcome by electrons generated in all valleys of 4H-SiC with increasing bias voltage while thicker barrier layers successfully minimize the collection of electrons in the M valley of SiC and therefore suppress the long-wavelength response >260 nm. (C) 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim C1 [Rodak, L. E.; Sampath, A. V.; Gallinat, C. S.; Smith, J.; Shen, H.; Wraback, M.] US Army Res Lab, Sensors & Electron Devices Directorate, RDRL SEEM M, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. [Chen, Y.; Zhou, Q.; Campbell, J. C.] Univ Virginia, Dept Elect & Comp Engn, Charlottesville, VA 22903 USA. RP Rodak, LE (reprint author), US Army Res Lab, Sensors & Electron Devices Directorate, RDRL SEEM M, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM Lee.Rodak.ctr@mail.mil FU U. S. Army Research Laboratory FX L. E. Rodak and C. Gallinat gratefully acknowledge support from the U. S. Army Research Laboratory Postdoctoral Fellowship Program administered by the Oak Ridge Associated Universities through a contract with the U. S. Army Research Laboratory. NR 8 TC 0 Z9 0 U1 1 U2 6 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA PAPPELALLEE 3, W-69469 WEINHEIM, GERMANY SN 1862-6351 J9 PHYS STATUS SOLIDI C PY 2014 VL 11 IS 3-4 BP 782 EP 785 DI 10.1002/pssc.201300684 PG 4 WC Nanoscience & Nanotechnology; Physics, Applied; Physics, Condensed Matter SC Science & Technology - Other Topics; Physics GA BB7WP UT WOS:000346071300102 ER PT S AU Moe, CG Garrett, GA Grandusky, JR Chen, JF Rodak, LE Rotella, P Wraback, M Schowalter, LJ AF Moe, Craig G. Garrett, Gregory A. Grandusky, James R. Chen, Jianfeng Rodak, Lee E. Rotella, Paul Wraback, Michael Schowalter, Leo J. BE Eddy, CR Kuball, M Koleske, DD Amano, H TI Correlation between optical and electrical performance of mid-ultraviolet light-emitting diodes on AlN substrates SO PHYSICA STATUS SOLIDI C: CURRENT TOPICS IN SOLID STATE PHYSICS, VOL 11, NO 3-4 SE Physica Status Solidi C-Current Topics in Solid State Physics LA English DT Proceedings Paper CT 10th International Conference on Nitride Semiconductors (ICNS) CY AUG 25-30, 2013 CL Washington, DC SP Off Naval Res, Army Res Off, Sandia Natl Lab, Natl Sci Fdn, Zeiss, Nichia, Laytec, Nitride Semicond Fdn Japan, Aixtron, Osram, Plasma Therm, Crystal IS, Dow Elect Mat DE AlGaN; ultraviolet LED; time-resolved photoluminescence; radiative lifetime AB Mid-ultraviolet LEDs grown on AlN substrates with a range of quantum efficiencies and wavelengths spanning 250 to 280 nm have been investigated by time-resolved photoluminescence and electroluminescence. Through scaling of room temperature internal quantum efficiencies across all devices, radiative and nonradiative lifetimes are also estimated. General trends observed include an increase in PL lifetime for longer wavelength and higher external quantum efficiency devices, consistent with the increase in the estimated nonradiative lifetime with increasing wavelength. Despite these trends, the external quantum efficiency of the devices increases only weakly with increasing wavelength from 258 to 279 nm, suggesting that optimization of radiative lifetime and injection efficiency also play an important role. (C) 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim C1 [Moe, Craig G.; Grandusky, James R.; Chen, Jianfeng; Schowalter, Leo J.] Crystal IS Inc, 70 Cohoes Ave, Green Isl, NY 12183 USA. [Garrett, Gregory A.; Rodak, Lee E.; Rotella, Paul; Wraback, Michael] U S Army Res Lab, Sensors & Elect Devices Directorate, Powder Mill Rd, MD 2800 USA. RP Moe, CG (reprint author), Crystal IS Inc, 70 Cohoes Ave, Green Isl, NY 12183 USA. EM moe@cisuvc.com NR 7 TC 4 Z9 4 U1 2 U2 8 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA PAPPELALLEE 3, W-69469 WEINHEIM, GERMANY SN 1862-6351 J9 PHYS STATUS SOLIDI C PY 2014 VL 11 IS 3-4 BP 786 EP 789 DI 10.1002/pssc.201300686 PG 4 WC Nanoscience & Nanotechnology; Physics, Applied; Physics, Condensed Matter SC Science & Technology - Other Topics; Physics GA BB7WP UT WOS:000346071300103 ER PT S AU Garrett, GA Shishehchi, S Rudin, S Malinovsky, V Wraback, M Bellotti, E AF Garrett, Gregory A. Shishehchi, Sara Rudin, Sergey Malinovsky, Vladimir Wraback, Michael Bellotti, Enrico BE Eddy, CR Kuball, M Koleske, DD Amano, H TI Experimental and theoretical study of dephasing processes in the kinetics of photoexcited carriers in GaN SO PHYSICA STATUS SOLIDI C: CURRENT TOPICS IN SOLID STATE PHYSICS, VOL 11, NO 3-4 SE Physica Status Solidi C-Current Topics in Solid State Physics LA English DT Proceedings Paper CT 10th International Conference on Nitride Semiconductors (ICNS) CY AUG 25-30, 2013 CL Washington, DC SP Off Naval Res, Army Res Off, Sandia Natl Lab, Natl Sci Fdn, Zeiss, Nichia, Laytec, Nitride Semicond Fdn Japan, Aixtron, Osram, Plasma Therm, Crystal IS, Dow Elect Mat DE time-resolved photoluminescence; carrier scattering; Monte-Carlo simulation ID LUMINESCENCE SPECTROSCOPY; ULTRAFAST CARRIER; SEMICONDUCTORS; DYNAMICS; COHERENT AB The scattering and dephasing processes that accompany the initial photoexcitation of electron-hole pairs in the semiconductor GaN are studied by sub-picosecond time-resolved photoluminescence. The rise time of the carrier recombination at the band edge after excitation 750 meV above the band gap is analyzed as a function of initial photoexcited carrier density and sample temperature. To elucidate the findings, simulations were performed based on a two band model with a non-parabolic conduction band and using a generalized Monte-Carlo technique. Results showed a small dependence in the rise time on the initial carrier density but a strong dependence on the sample temperature, where simulation and experiment scaled proportionately. (C) 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim C1 [Garrett, Gregory A.; Rudin, Sergey; Malinovsky, Vladimir; Wraback, Michael] US Army Res Lab, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA. [Shishehchi, Sara; Bellotti, Enrico] Boston Univ, ECE Dept, Boston, MA 02215 USA. RP Garrett, GA (reprint author), US Army Res Lab, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA. EM gregory.a.garrett.civ@mail.mil FU BU Photonics Center; U. S. Army Research Laboratory through the Collaborative Research Alliance for MultiScale multidisciplinary Modeling of Electronic materials ( CRA- MSME) FX The work at Boston University has been supported in part by the BU Photonics Center and by the U. S. Army Research Laboratory through the Collaborative Research Alliance for MultiScale multidisciplinary Modeling of Electronic materials ( CRA- MSME). The authors would like to thank Crystal IS, Green Island, NY, for growth of the GaN sample. NR 10 TC 1 Z9 1 U1 0 U2 3 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA PAPPELALLEE 3, W-69469 WEINHEIM, GERMANY SN 1862-6351 J9 PHYS STATUS SOLIDI C PY 2014 VL 11 IS 3-4 BP 824 EP 827 DI 10.1002/pssc.201300688 PG 4 WC Nanoscience & Nanotechnology; Physics, Applied; Physics, Condensed Matter SC Science & Technology - Other Topics; Physics GA BB7WP UT WOS:000346071300113 ER PT S AU Salzer, WL Asselin, BL Plourde, PV Corn, T Hunger, SP AF Salzer, Wanda L. Asselin, Barbara L. Plourde, Paul V. Corn, Tim Hunger, Stephen P. GP Annals New York Acad Sci TI Development of asparaginase Erwinia chrysanthemi for the treatment of acute lymphoblastic leukemia SO PHARMACEUTICAL SCIENCE TO IMPROVE THE HUMAN CONDITION: WINNERS AND FINALISTS FOR THE PRIX GALIEN USA AWARDS 2013 SE Annals of the New York Academy of Sciences LA English DT Article; Book Chapter DE asparaginase; Erwinia chrysanthemi; leukemia; hypersensitivity ID MINIMAL RESIDUAL DISEASE; COLI L-ASPARAGINASE; CHILDRENS ONCOLOGY GROUP; GUINEA-PIG SERUM; ACUTE LYMPHOCYTIC-LEUKEMIA; FARBER-CANCER-INSTITUTE; ESCHERICHIA-COLI; ANTITUMOR-ACTIVITY; DANA-FARBER; POLYETHYLENE-GLYCOL AB Since it was identified in 1963 as the antileukemic agent in guinea pig serum, L-asparaginase (ASNase) has become an integral component of chemotherapy protocols to treat patients with acute lymphoblastic leukemia (ALL). Escherichia coli and Erwinia chrysanthemi provide the sources of ASNase used clinically today. From the time ASNase was first introduced into treatment protocols, the 5-year survival rate has increased significantly, particularly in children and adolescents. E. coli-derived ASNase was approved in 1978 to be used as part of a multiagent chemotherapy to treat ALL. However, the development of hypersensitivity in 10-30% of patients often leads to treatment discontinuation. E. chrysanthemi-derived ASNase (referred to herein as ASNase Erwinia chrysanthemi) is immunologically distinct from E. coli ASNase and therefore does not cross-react with the E. coli enzyme. In 2011, ASNase Erwinia chrysanthemi was approved in the United States for patients who develop hypersensitivity to E. coli-derived ASNase. When indicated, a switch from ASNase E. coli to ASNase E. chrysanthemi allows patients to continue to receive treatment and maintain therapeutic levels of ASNase activity. Therapeutic drug monitoring may help ensure that therapeutic enzyme levels are maintained. Pegylated recombinant ASNase Erwinia chrysanthemi is currently being developed to improve pharmacokinetic properties and reduce immunogenicity. C1 [Salzer, Wanda L.] US Army Med Res & Mat Command, Ft Detrick, MD 21702 USA. [Asselin, Barbara L.] Univ Rochester, Med Ctr, Golisano Childrens Hosp, Dept Pediat,Sch Med, Rochester, NY 14642 USA. [Plourde, Paul V.] Jazz Pharmaceut Inc, Palo Alto, CA USA. [Corn, Tim] EUSA Pharma, Dept Clin Oncol, Oxford, England. [Hunger, Stephen P.] Univ Colorado, Sch Med, Dept Pediat, Aurora, CO USA. [Hunger, Stephen P.] Childrens Hosp Colorado, Aurora, CO USA. RP Salzer, WL (reprint author), US Army Med Res & Mat Command, Ft Detrick, MD 21702 USA. EM wanda.l.salzer.mil@mail.mil NR 82 TC 7 Z9 8 U1 1 U2 7 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND SN 0077-8923 J9 ANN NY ACAD SCI JI Ann.NY Acad.Sci. PY 2014 VL 1329 BP 81 EP 92 DI 10.1111/nyas.12496 PG 12 WC Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA BB7SZ UT WOS:000345982000007 PM 25098829 ER PT J AU Rogers, JR McVay, RC AF Rogers, John R. McVay, R. Clayton GP IEEE TI Robotics Education in the Liberal Arts Curriculum SO 2014 IEEE INNOVATIONS IN TECHNOLOGY CONFERENCE (INNOTEK) LA English DT Proceedings Paper CT IEEE Innovations in Technology Conference (InnoTek) CY MAY 16, 2014 CL Warwick, RI SP IEEE, IEEE USA, Innovation DE military; programming; robot; education; mechatronics AB The United States Military Academy is offers a liberal arts curriculum. This paper describes how robotics topics are integrated where possible in that curriculum. The military leadership recognizes the need for its members to have knowledge of robotics in today's technological Army. Among soldiers and officers the depth of knowledge needed ranges from awareness of capability to a deep engineering understanding of design paired with hands-on skill. West Point educates young men and women who are to be future Army officers. This paper presents several methods used at West Point to build robotics knowledge according to the need of the individual. Robotics education is executed in spite of a crowded liberal arts curriculum. Methods include K-12 outreach, projects, internships, courses for non-engineering majors, and engineering degree programs. Knowledge is transferred not only by graduates, but also by the rotating officer faculty who return to serve in the Army at large after teaching at West Point. C1 [Rogers, John R.; McVay, R. Clayton] US Mil Acad, Dept Civil & Mech Engn, West Point, NY 10996 USA. RP Rogers, JR (reprint author), US Mil Acad, Dept Civil & Mech Engn, West Point, NY 10996 USA. EM john.rogers@usma.edu; robert.c.mcvay.mil@mail.mil NR 18 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA PY 2014 PG 5 WC Computer Science, Interdisciplinary Applications; Engineering, Multidisciplinary SC Computer Science; Engineering GA BB7MT UT WOS:000345758700007 ER PT J AU Shoop, BL AF Shoop, Barry L. GP IEEE TI Developing Critical Thinking, Creativity and Innovation Skills SO 2014 IEEE INNOVATIONS IN TECHNOLOGY CONFERENCE (INNOTEK) LA English DT Proceedings Paper CT IEEE Innovations in Technology Conference (InnoTek) CY MAY 16, 2014 CL Warwick, RI SP IEEE, IEEE USA, Innovation DE Critical thinking; creativity; disruptive innovation; education AB A desirable goal of engineering education is to teach students how to think critically and be creative and innovative. However, the speed of technological innovation and the continual expansion of disciplinary knowledge leave little time in the curriculum for students to formally study innovation, particularly at the undergraduate level. At West Point we have developed a novel upper-division interdisciplinary undergraduate engineering course that simultaneously develops the critical thinking, creativity and innovation of our students. This course is structured as a deliberate interactive engagement between students and faculty that employs the Socratic Method to develop an understanding of disruptive and innovative technologies and a historical context of how social, cultural, and religious factors impact the acceptance or rejection of innovation. The course begins by developing the background understanding of what disruptive technology is and a historical context about successes and failures of social, cultural, and religious acceptance of technological innovation. To develop this framework, students read The Innovator's Dilemma by Clayton M. Christensen, The Structure of Scientific Revolutions by Thomas S. Kuhn, The Discoverers by Daniel J. Boorstin, and The Two Cultures by C. P. Snow. For each class meeting, students also read current scientific and technical literature and come prepared to discuss current events related to technological innovation. Each student researches potential disruptive technologies and prepares a compelling argument of why the specific technologies are disruptive so they can defend their choice and rationale. During course meetings students discuss the readings and specific technologies found during their independent research. As part of this research, each student has the opportunity to interview forward thinking technology leaders in their respective fields of interest. C1 US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. RP Shoop, BL (reprint author), US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. EM b.shoop@ieee.org NR 20 TC 0 Z9 0 U1 1 U2 6 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA PY 2014 PG 6 WC Computer Science, Interdisciplinary Applications; Engineering, Multidisciplinary SC Computer Science; Engineering GA BB7MT UT WOS:000345758700001 ER PT S AU Zeino, E Paulik, M Krishnan, M Luo, CM Overholt, J Hudas, G Udvare, T AF Zeino, Eyad Paulik, Mark Krishnan, Mohan Luo, Chaomin Overholt, James Hudas, Greg Udvare, Thomas GP IEEE TI Ground-Truth Localization Using a Sequential-Update Extended Kalman Filter SO 2014 IEEE INTERNATIONAL CONFERENCE ON ELECTRO/INFORMATION TECHNOLOGY (EIT) SE International Conference on Electro Information Technology LA English DT Proceedings Paper CT IEEE International Conference on Electro/Information Technology (EIT) CY JUN 05-07, 2014 CL Milwaukee, WI SP IEEE DE Extended Kalman Filter; Multi-Sensor Fusion; Odometry Calibration; Sequential Sensor Fusion; Localization AB A ground-truth environment for mobile robot localization is developed. The sequential update extended Kalman filter is employed to fuse data from a Sick Nav200 laser positioning system and multiple onboard sensors to provide highly accurate robot pose estimation. Results are suitable for validation of mapping, localization and kino-dynamic modeling. Experimental work presented covers odometry calibration and system validation. C1 [Zeino, Eyad; Paulik, Mark; Krishnan, Mohan; Luo, Chaomin] Univ Detroit Mercy, Dept Elect & Comp Engn, 4001 W McNichols Rd, Detroit, MI 48221 USA. [Overholt, James; Hudas, Greg; Udvare, Thomas] US Army, RDECOM TARDEC, Ground Vehicle Robot, RDTA RS 263, Warren, MI 48397 USA. RP Zeino, E (reprint author), Univ Detroit Mercy, Dept Elect & Comp Engn, 4001 W McNichols Rd, Detroit, MI 48221 USA. EM paulikmj@udmercy.edu; james.overholt@wpafb.at.mil NR 12 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2154-0357 BN 978-1-4799-4774-4 J9 INT CONF ELECTRO INF PY 2014 BP 103 EP 108 PG 6 WC Computer Science, Interdisciplinary Applications; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BB7LX UT WOS:000345737700002 ER PT S AU Yang, W Ji, Y Ye, JW Young, SS Yu, JY AF Yang, Wei Ji, Yu Ye, Jinwei Young, S. Susan Yu, Jingyi BE Fleet, D Pajdla, T Schiele, B Tuytelaars, T TI Coplanar Common Points in Non-centric Cameras SO COMPUTER VISION - ECCV 2014, PT I SE Lecture Notes in Computer Science LA English DT Proceedings Paper CT 13th European Conference on Computer Vision (ECCV) CY SEP 06-12, 2014 CL Zurich, SWITZERLAND AB Discovering and extracting new image features pertaining to scene geometry is important to 3D reconstruction and scene understanding. Examples include the classical vanishing points observed in a centric camera and the recent coplanar common points (CCPs) in a crossed-slit camera [21,17]. A CCP is a point in the image plane corresponding to the intersection of the projections of all lines lying on a common 3D plane. In this paper, we address the problem of determining CCP existence in general non-centric cameras. We first conduct a ray-space analysis to show that finding the CCP of a 3D plane is equivalent to solving an array of ray constraint equations. We then derive the necessary and sufficient conditions for CCP to exist in an arbitrary non-centric camera such as non-centric catadioptric mirrors. Finally, we present robust algorithms for extracting the CCPs from a single image and validate our theories and algorithms through experiments. C1 [Yang, Wei; Ji, Yu; Yu, Jingyi] Univ Delaware, Newark, DE 19716 USA. [Ye, Jinwei; Young, S. Susan] US Army Res Lab, Adelphi, MD 20783 USA. RP Yang, W (reprint author), Univ Delaware, Newark, DE 19716 USA. FU National Science Foundation [IIS-CAREER-0845268, IIS-1218156] FX This project was partially supported by the National Science Foundation under grants IIS-CAREER-0845268 and IIS-1218156. NR 22 TC 1 Z9 1 U1 0 U2 0 PU SPRINGER INT PUBLISHING AG PI CHAM PA GEWERBESTRASSE 11, CHAM, CH-6330, SWITZERLAND SN 0302-9743 BN 978-3-319-10590-1; 978-3-319-10589-5 J9 LECT NOTES COMPUT SC PY 2014 VL 8689 BP 220 EP 233 PG 14 WC Computer Science, Artificial Intelligence; Computer Science, Theory & Methods; Imaging Science & Photographic Technology SC Computer Science; Imaging Science & Photographic Technology GA BB7GU UT WOS:000345524200015 ER PT S AU Redding, B Pan, Y Wang, C Videen, G Cao, H AF Redding, B. Pan, Y. Wang, C. Videen, G. Cao, Hui BE VoDinh, T Lieberman, RA Gauglitz, GG TI Polarization resolved angular optical scattering of aerosol particles SO ADVANCED ENVIRONMENTAL, CHEMICAL, AND BIOLOGICAL SENSING TECHNOLOGIES XI SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Advanced Environmental, Chemical, and Biological Sensing Technologies XI CY MAY 05-06, 2014 CL Baltimore, MD SP SPIE DE angular optical scattering; aerosol particles; polarization aspect ratio ID DIFFERENTIAL LIGHT-SCATTERING; NEGATIVE POLARIZATION; SIZE AB Real-time detection and identification of bio-aerosol particles are crucial for the protection against chemical and biological agents. The strong elastic light scattering properties of airborne particles provides a natural means for rapid, non-invasive aerosol characterization. Recent theoretical predictions suggested that variations in the polarization dependent angular scattering cross section could provide an efficient means of classifying different airborne particles. In particular, the polarization dependent scattering cross section of aggregate particles is expected to depend on the shape of the primary particles. In order to experimentally validate this prediction, we built a high throughput, sampling system, capable of measuring the polarization resolved angular scattering cross section of individual aerosol particles flowing through an interrogating volume with a single shot of laser pulse. We calibrated the system by comparing the polarization dependent scattering cross section of individual polystyrene spheres with that predicted by Mie theory. We then used the system to study different particles types: Polystyrene aggregates composed 500 nm spheres and Bacillus subtilis (BG, Anthrax simulant) spores composed of elongated 500 nm x 1000 nm cylinder-line particles. We found that the polarization resolved scattering cross section depends on the shape of the constituent elements of the aggregates. This work indicates that the polarization resolved scattering cross section could be used for rapid discrimination between different bio-aerosol particles. C1 [Redding, B.; Cao, Hui] Yale Univ, Dept Appl Phys, New Haven, CT 06520 USA. [Pan, Y.; Wang, C.; Videen, G.] US Army Res Lab, Adelphi, MD 20783 USA. [Wang, C.] Mississippi State Univ, Dept Phys, Starkville, MS 39759 USA. RP Redding, B (reprint author), Yale Univ, Dept Appl Phys, New Haven, CT 06520 USA. EM brandon.redding@yale.edu NR 13 TC 0 Z9 0 U1 0 U2 5 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-043-3 J9 PROC SPIE PY 2014 VL 9106 AR UNSP 91060F DI 10.1117/12.2050022 PG 6 WC Remote Sensing; Optics SC Remote Sensing; Optics GA BB6WE UT WOS:000345068700008 ER PT J AU Kiris, E Burnett, JC Kane, CD Bavari, S AF Kiris, Erkan Burnett, James C. Kane, Christopher D. Bavari, Sina TI Recent Advances in Botulinum Neurotoxin Inhibitor Development SO CURRENT TOPICS IN MEDICINAL CHEMISTRY LA English DT Review DE Botulinum neurotoxin; botulism; drug discovery; neuronal-based therapeutics; small molecule botulinum inhibitors; SNARE ID SMALL-MOLECULE INHIBITORS; TOXIN TYPE-A; EATON MYASTHENIC SYNDROME; UBIQUITIN-PROTEASOME SYSTEM; NERVE-HEMIDIAPHRAGM PREPARATIONS; SPINAL MUSCULAR-ATROPHY; DOMAIN-BASED ASSAYS; GROWTH-FACTOR I; LIGHT-CHAIN; SEROTYPE-A AB Botulinum neurotoxins (BoNTs) are endopeptidases that target motor neurons and block acetylcholine neurotransmitter release. This action results in the muscle paralysis that defines the disease botulism. To date, there are no FDA-approved therapeutics to treat BoNT-mediated paralysis after intoxication of the motor neuron. Importantly, the rationale for pursuing treatments to counter these toxins is driven by their potential misuse. Current drug discovery efforts have mainly focused on small molecules, peptides, and peptidomimetics that can directly and competitively inhibit BoNT light chain proteolytic activity. Although this is a rational approach, direct inhibition of the Zn2+ metalloprotease activity has been elusive as demonstrated by the dearth of candidates undergoing clinical evaluation. Therefore, broadening the scope of viable targets beyond that of active site protease inhibitors represents an additional strategy that could move the field closer to the clinic. Here we review the rationale, and discuss the outcomes of earlier approaches and highlight potential new targets for BoNT inhibition. These include BoNT uptake and processing inhibitors, enzymatic inhibitors, and modulators of neuronal processes associated with toxin clearance, neurotransmitter potentiation, and other pathways geared towards neuronal recovery and repair. C1 [Kiris, Erkan] Geneva Fdn, Frederick, MD 21702 USA. [Kiris, Erkan; Kane, Christopher D.; Bavari, Sina] US Army, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA. [Kiris, Erkan] FNLCR, Frederick, MD USA. [Burnett, James C.] Leidos Biomed Res Inc, FNLCR, CDDG, Ft Detrick, MD 21702 USA. [Burnett, James C.] FNLCR, CDDG, Dev Therapeut Program, Frederick, MD 21702 USA. [Kane, Christopher D.] Henry M Jackson Fdn, Frederick, MD USA. [Kane, Christopher D.] US Army, DoD Biotechnol High Performance Comp Software App, TATRC, Med Res & Mat Command, Ft Detrick, MD 21702 USA. RP Bavari, S (reprint author), US Army, Med Res Inst Infect Dis, 1425 Porter St, Ft Detrick, MD 21702 USA. EM sina.bavari.civ@mail.mil FU National Institutes of Health [1 R21 AI101387-01, 5 U01AI082051-05]; Defense Threat Reduction Agency FX This work was supported by grants from the National Institutes of Health (1 R21 AI101387-01 and 5 U01AI082051-05) and the Defense Threat Reduction Agency. NR 179 TC 8 Z9 9 U1 1 U2 9 PU BENTHAM SCIENCE PUBL LTD PI SHARJAH PA EXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES SN 1568-0266 EI 1873-4294 J9 CURR TOP MED CHEM JI Curr. Top. Med. Chem. PY 2014 VL 14 IS 18 BP 2044 EP 2061 PG 18 WC Chemistry, Medicinal SC Pharmacology & Pharmacy GA AT9CR UT WOS:000345226200002 PM 25335887 ER PT S AU Tahmoush, D AF Tahmoush, David BE Ternovsky, IV Chin, P TI Securing Radars Using Secure Wireless Sensor Networking SO CYBER SENSING 2014 SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Cyber Sensing CY MAY 06, 2014 CL Baltimore, MD SP SPIE DE radar; wireless sensor network; security ID AD HOC NETWORKS; CRYPTOSYSTEMS; INTERFERENCE AB Radar sensors can be viewed as a limited wireless sensor network consisting of radar transmitter nodes, target nodes, and radar receiver nodes. The radar transmitter node sends a communication signal to the target node which then reflects it in a known pattern to the radar receiver nodes. This type of wireless sensor network is susceptible to the same types of attacks as a traditional wireless sensor network, but there is less opportunity for defense. The target nodes in the network are unable to validate the return signal, and they are often uncooperative. This leads to ample opportunities for spoofing and man-in-the-middle attacks. This paper explores some of the fundamental techniques that can be used against a limited wireless network system as well as explores the techniques that can be used to counter them. C1 Univ Maryland, Univ Coll, US Army Res Lab, College Pk, MD 20742 USA. RP Tahmoush, D (reprint author), Univ Maryland, Univ Coll, US Army Res Lab, College Pk, MD 20742 USA. NR 39 TC 0 Z9 0 U1 1 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-034-1 J9 PROC SPIE PY 2014 VL 9097 AR 90970B DI 10.1117/12.2050042 PG 7 WC Remote Sensing; Optics SC Remote Sensing; Optics GA BB6UH UT WOS:000345030300008 ER PT S AU Robinson, E D'Souza, AI Ionescu, AC Okerlund, D de Lyon, TJ Rajavel, RD Sharifi, H Dhar, NK Wijewarnasuriya, PS Grein, C AF Robinson, E. D'Souza, A. I. Ionescu, A. C. Okerlund, D. de Lyon, T. J. Rajavel, R. D. Sharifi, H. Dhar, N. K. Wijewarnasuriya, P. S. Grein, C. BE LeVan, PD Sood, AK Wijewarnasuriya, P DSouza, AI TI MWIR InAsSb FPA Data and Analysis SO INFRARED SENSORS, DEVICES, AND APPLICATIONS IV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Infrared Sensors, Devices, and Applications IV CY AUG 18-20, 2014 CL San Diego, CA SP SPIE AB InAsSb material with a cutoff wavelength in the 5 mu m range has been grown on GaAs substrates. The MWIR InAsSb detector arrays were fabricated and hybridized to a ROIC to permit measurement of the electrical and optical properties of detectors. Detector arrays were fabricated in a 1024 x 1024 format on an 18 mu m pitch. A fanout was utilized to directly acquire data from a set of selected detectors without an intervening read out integrating circuit (ROIC). Variable temperature J(dark) vs V-d measurements have been made with the dark current density similar to 10-5 A/cm(2) at 150 K. The external QE measured using a narrow band filter centered at similar to 4 mu m had values in the 65 - 70 % range. Since the detectors were illuminated through a GaAs substrate, which has a reflectance of 29%, the internal QE is greater than 90 %. A 1024 x 1024 ROIC on an 18 mu m pitch was also designed and fabricated to interface with the barrier detectors. The ROIC operates at 30 Hz frame rate and has a well capacity of 20.7 M electrons. QE at 150 K for a 1024 x 1024 detector array hybridized to a ROIC had a median D* at 150 K under a flux of 1.07 x 10(15) ph/(cm(2)/s) was 1.2 x 10(11) cm Hz(1/2)/W. The NEdT was 44 mK and imagery was obtained at 150 K using an f/2.3 MWIR lens. C1 [Robinson, E.; D'Souza, A. I.; Ionescu, A. C.; Okerlund, D.] DRS Sensors & Targeting Syst, 10600 Valley View St, Cypress, CA 90630 USA. [de Lyon, T. J.; Rajavel, R. D.; Sharifi, H.] HRL Labs, LLC, Malibu, CA 90265 USA. [Dhar, N. K.] DARPA, MTO, Arlington, VA 22203 USA. [Wijewarnasuriya, P. S.] US Army Res Lab, Adelphi, MD 20783 USA. [Grein, C.] Univ Illinois, Chicago, IL 60607 USA. RP Robinson, E (reprint author), DRS Sensors & Targeting Syst, 10600 Valley View St, Cypress, CA 90630 USA. FU DARPA [N66604-09-C-3652]; Department of Defense or the U. S. Government; DoDI [5230.29] FX This work was supported by DARPA under contract N66604-09-C-3652 (Dr. Nibir Dhar, DARPA Program Manager). However, " The views expressed are those of the author and do not reflect the official policy or position of the Department of Defense or the U. S. Government." This is in accordance with DoDI 5230.29, January 8, 2009. The paper is approved for public release, distribution unlimited. NR 4 TC 1 Z9 1 U1 0 U2 5 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-247-5 J9 PROC SPIE PY 2014 VL 9220 AR UNSP 92200D DI 10.1117/12.2064665 PG 7 WC Remote Sensing; Optics SC Remote Sensing; Optics GA BB6UE UT WOS:000345027200011 ER PT S AU Sun, J Choi, KK Jhabvala, MD Jhabvala, CA Waczynski, A Olver, K AF Sun, J. Choi, K. K. Jhabvala, M. D. Jhabvala, C. A. Waczynski, A. Olver, K. BE LeVan, PD Sood, AK Wijewarnasuriya, P DSouza, AI TI Fabrication of Resonator-Quantum Well Infrared Photodetector test devices and focal plane arrays SO INFRARED SENSORS, DEVICES, AND APPLICATIONS IV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Infrared Sensors, Devices, and Applications IV CY AUG 18-20, 2014 CL San Diego, CA SP SPIE DE inductively coupled plasma etching; Resonator-quantum well infrared photodetectors focal plane array; GaAs substrate removal ID DAMAGE; GAAS; SICL4; TIME; INP AB Resonator-Quantum Well Infrared Photodetectors (R-QWIPs) are the next generation of QWIP detectors that use resonances to increase the quantum efficiency (QE). To achieve the expected performance, the detector geometry must be produced in precise specification. In particular, the height of the diffractive elements (DE) and the thickness of the active resonator must be uniformly and accurately realized to within 0.05 mu m accuracy and the substrates of the detectors have to be removed totally. To achieve these specifications, two optimized inductively coupled plasma (ICP) etching processes are developed. Using these etching techniques, we have fabricated a number of R-QWIP test detectors and FPAs with the required dimensions and completely removed their substrates. The QE spectra were tested to be in close agreement with the theoretical predictions. The operability and spectral uniformity of the focal plane array (FPA) is about 99.1% and 3% respectively. C1 [Sun, J.; Choi, K. K.; Jhabvala, M. D.; Jhabvala, C. A.; Waczynski, A.; Olver, K.] US Army Res Lab, Adelphi, MD 20783 USA. [Sun, J.; Choi, K. K.; Jhabvala, M. D.; Jhabvala, C. A.; Waczynski, A.; Olver, K.] NASA Goddard Space Flight Ctr, Greenbelt, MD USA. RP Sun, J (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. NR 15 TC 0 Z9 0 U1 0 U2 4 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-247-5 J9 PROC SPIE PY 2014 VL 9220 AR UNSP 922004 DI 10.1117/12.2061985 PG 11 WC Remote Sensing; Optics SC Remote Sensing; Optics GA BB6UE UT WOS:000345027200002 ER PT J AU Carah, JK Blencowe, CC Wright, DW Bolton, LA AF Carah, Jennifer K. Blencowe, Christopher C. Wright, David W. Bolton, Lisa A. TI Low-Cost Restoration Techniques for Rapidly Increasing Wood Cover in Coastal Coho Salmon Streams SO NORTH AMERICAN JOURNAL OF FISHERIES MANAGEMENT LA English DT Article ID PACIFIC-NORTHWEST WATERSHEDS; JUVENILE SALMONIDS; DEBRIS; WASHINGTON; RIPARIAN; REHABILITATION; MANAGEMENT; CALIFORNIA; OREGON; RIVERS AB Like many rivers and streams in forests of the Pacific Northwest, California north coast rivers and streams have been depleted of downed wood through timber harvest and direct wood removal. Due to the important role of wood in creating and maintaining salmonid habitat, wood augmentation has become a common element of stream restoration. Restoration efforts in North America often focus on building anchored, engineered wood structures at the site scale; however, these projects can fail to meet restoration goals at the watershed scale, do not closely mimic natural wood loading processes or dynamics, and can be expensive to implement. For critically imperiled populations of Coho Salmon Oncorhynchus kisutch in California, there is a strong impetus to achieve as much habitat restoration as possible in priority watersheds in the shortest time and with limited resources, so cost-efficient techniques are necessary. In this multi-site project, we investigated unanchored techniques for wood loading to evaluate cost and contribution to salmonid habitat in Mendocino County, California. Over a period of 6 years, 72.4 km of stream were treated with 1,973 pieces of strategically placed wood. We found that unanchored wood loading techniques were much less costly than commonly used anchored techniques, reliably improved habitat, and retained wood at high rates (mean = 92%) in small-to moderate-sized streams, at least over the short term (<6 years). The average cost of design and construction for the unanchored projects was US$259 per log, equivalent to 22% of the cost associated with the anchored wood augmentation methods examined here. Our results suggest that this unanchored wood loading approach has the potential to increase the pace and scale at which wood augmentation projects are implemented in the Pacific Northwest and beyond. C1 [Carah, Jennifer K.] Nature Conservancy, San Francisco, CA 94105 USA. [Blencowe, Christopher C.] Blencowe Watershed Management, Ft Bragg, CA 95437 USA. [Wright, David W.] Campbell Timberland Management, Ft Bragg, CA 95437 USA. [Bolton, Lisa A.] Trout Unltd, Ft Bragg, CA 95437 USA. RP Carah, JK (reprint author), Nature Conservancy, 201 Mission St,4th Floor, San Francisco, CA 94105 USA. EM jcarah@tnc.org FU Hawthorne Timber Company; Conservation Fund; Weger Associates; Redwood Forest Foundation; California State Parks; National Oceanic and Atmospheric Administration Community-Based Restoration Program [1051253804, 1981483953]; Nature Conservancy [1051253804, 1981483953]; California Department of Fish and Wildlife Fisheries Restoration Grant Program [P0530420, P0710546, P0810522, P0910519, P1010303, P1010306, P1010309, P1010507, P1181002]; Felton Family Foundation FX We thank Hawthorne Timber Company, The Conservation Fund, Weger Associates, Redwood Forest Foundation, and California State Parks for supporting the implementation of these projects on their properties. We also thank The Nature Conservancy, Trout Unlimited, Campbell Timberland Management, and The Conservation Fund staff members who dedicated countless hours to these projects. Special thanks are extended to Ken Smith and Allison Chambers for their work in building these projects. Work was completed under grants from the national partnership between the National Oceanic and Atmospheric Administration Community-Based Restoration Program and The Nature Conservancy (awards 1051253804 and 1981483953), the California Department of Fish and Wildlife Fisheries Restoration Grant Program (awards P0530420, P0710546, P0810522, P0910519, P1010303, P1010306, P1010309, P1010507, and P1181002), the Felton Family Foundation, and The Nature Conservancy. We are also grateful to Tim Beechie, Lisa Hulette, Peter Kareiva, Stacey Solie, and two anonymous reviewers, who provided thoughtful comments and critiques that improved the manuscript. NR 57 TC 3 Z9 3 U1 3 U2 15 PU TAYLOR & FRANCIS INC PI PHILADELPHIA PA 530 WALNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA SN 0275-5947 EI 1548-8675 J9 N AM J FISH MANAGE JI North Am. J. Fish Manage. PY 2014 VL 34 IS 5 BP 1003 EP 1013 DI 10.1080/02755947.2014.943861 PG 11 WC Fisheries SC Fisheries GA AT3AS UT WOS:000344807700013 ER PT S AU Gupta, N AF Gupta, Neelam BE Chenault, DB Goldstein, DH TI Development of Spectropolarimetric Imagers from 400 to 1700 nm SO POLARIZATION: MEASUREMENT, ANALYSIS, AND REMOTE SENSING XI SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Polarization - Measurement, Analysis, and Remote Sensing XI CY MAY 05-06, 2014 CL Baltimore, MD SP SPIE DE Hyperspectral; polarization; VNIR; SWIR; acousto-optic tunable filter; TeO2; liquid crystal variable retarders; LCVR; Mueller Matrix; imager ID ACOUSTOOPTIC TUNABLE FILTER; CRYSTALS; POLARIMETER; SYSTEM AB Development of two prototype field-portable hyperspectral imagers that will also collect polarization signatures is being carried out in the visible-near infrared (VNIR) and the shortwave infrared (SWIR) regions. Each of these imagers uses a TeO2 noncollinear acousto-optic tunable filter (AOTF) and two liquid crystal variable retarders (LCVRs). The spectral region of operation for the first imager is from 400 to 800 nm and for the second one from 900 to 1700 nm. We will present the optical design and Mueller Matrix analysis results. C1 US Army Res Lab, Adelphi, MD 20817 USA. RP Gupta, N (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20817 USA. NR 29 TC 3 Z9 4 U1 0 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-036-5 J9 PROC SPIE PY 2014 VL 9099 AR 90990N DI 10.1117/12.2052947 PG 11 WC Remote Sensing; Optics SC Remote Sensing; Optics GA BB6TX UT WOS:000345017900018 ER PT S AU Gurton, KP Yuffa, AJ Videen, G AF Gurton, Kristan P. Yuffa, Alex J. Videen, Gorden BE Chenault, DB Goldstein, DH TI LWIR Polarimetry for Enhanced Facial Recognition in Thermal Imagery SO POLARIZATION: MEASUREMENT, ANALYSIS, AND REMOTE SENSING XI SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Polarization - Measurement, Analysis, and Remote Sensing XI CY MAY 05-06, 2014 CL Baltimore, MD SP SPIE DE Imaging systems; Infrared; Polarimetric imaging; Passive remote sensing ID SURFACE-ROUGHNESS; POLARIZATION; RADIATION; EMISSION AB We present a series of long-wave-infrared (LWIR) polarimetric-based thermal images of facial profiles in which polarization-state information of the image forming radiance is retained and displayed. The resultant polarimetric images show enhanced facial features, additional texture, and details that are not present in the corresponding conventional thermal imagery. It has been generally thought that conventional thermal imagery (MidIR or LWIR) could not produce the detailed spatial information required for reliable human identification due to the so-called "ghosting" effect often seen in thermal imagery of human subjects. By using polarimetric information, we are able to extract subtle surface features of the human face, thus improving subject identification. The considered polarimetric image sets include the conventional thermal intensity image, S-0, the two Stokes images, S-1 and S-2, and a Stokes image product called the degree-of-linear-polarization (DoLP) image. Finally, Stokes imagery is combined with Fresnel relations to extract additional 3D surface information. C1 [Gurton, Kristan P.; Yuffa, Alex J.; Videen, Gorden] US Army Res Lab, Computat & Informat Sci Directorate, Adelphi, MD 20783 USA. RP Gurton, KP (reprint author), US Army Res Lab, Computat & Informat Sci Directorate, Adelphi, MD 20783 USA. EM kristan.p.gurton.civ@mail.mil RI Yuffa, Alex/B-5498-2014 OI Yuffa, Alex/0000-0002-3600-1131 NR 15 TC 0 Z9 0 U1 0 U2 1 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-036-5 J9 PROC SPIE PY 2014 VL 9099 AR 90990G DI 10.1117/12.2049700 PG 9 WC Remote Sensing; Optics SC Remote Sensing; Optics GA BB6TX UT WOS:000345017900011 ER PT S AU Hodgkin, VA Deaver, DM LeMaster, DA AF Hodgkin, Van A. Deaver, Dawne M. LeMaster, Daniel A. BE Chenault, DB Goldstein, DH TI Preliminary Measurements of Contrast in Polarimetric Signatures of Humans SO POLARIZATION: MEASUREMENT, ANALYSIS, AND REMOTE SENSING XI SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Polarization - Measurement, Analysis, and Remote Sensing XI CY MAY 05-06, 2014 CL Baltimore, MD SP SPIE DE Shortwave Infrared; Polarimetry; Mueller Matrix; Stokes Vectors; Image Contrast AB The reflective bands in modern imaging, i.e., the visible through the short wave infrared (SWIR), have become very attractive for use in both daytime and low light target acquisition and surveillance. In addition, the nature of the target in modern conflict again includes the human body as a principle target. The spectral natures of the reflectivities of humans, their clothing, what they may be carrying, and the environments in which they are immersed, along with the spectral nature and strength of the light sources that illuminate them, have been the essential components of the contrasts in the signatures that are used in models that predict probabilities of target acquisition and discrimination. What has been missing is the impact that polarization in these signatures can have on image contrast. This paper documents a preliminary investigation into the contrast in active and passive polarimetric signatures of humans holding two-handed objects in the SWIR. C1 [Hodgkin, Van A.; Deaver, Dawne M.] US Army RDECOM CERDEC NVESD, Ft Belvoir, VA 22060 USA. [LeMaster, Daniel A.] US Air Force Res Lab, Wright Patterson AFB, OH USA. RP Hodgkin, VA (reprint author), US Army RDECOM CERDEC NVESD, Ft Belvoir, VA 22060 USA. NR 5 TC 0 Z9 0 U1 0 U2 0 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-036-5 J9 PROC SPIE PY 2014 VL 9099 AR UNSP 90990D DI 10.1117/12.2050328 PG 10 WC Remote Sensing; Optics SC Remote Sensing; Optics GA BB6TX UT WOS:000345017900009 ER PT S AU Romano, JM Rosario, D AF Romano, Joao M. Rosario, Dalton BE Chenault, DB Goldstein, DH TI A covariance-based anomaly detector for polarimetric remote sensing applications SO POLARIZATION: MEASUREMENT, ANALYSIS, AND REMOTE SENSING XI SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Polarization - Measurement, Analysis, and Remote Sensing XI CY MAY 05-06, 2014 CL Baltimore, MD SP SPIE DE polarimetric; LWIR; anomaly; detector; SPICE; covariance test ID MATERIAL CLASSIFICATION; IMAGERY AB The proposed paper recommends a new anomaly detection algorithm for polarimetric remote sensing applications based on the M-Box covariance test by taking advantage of key features found in a multi-polarimetric data cube. The paper demonstrates: 1) that independent polarization measurements contain information suitable for manmade object discrimination from natural clutter; 2) analysis between the variability exhibited by manmade objects relative to natural clutter; 3) comparison between the proposed M-Box covariance test with Stokes parameters S-0 and S-1, DoLP, RX-Stokes, and PCA RX-Stokes; and finally 4) the data used for the comparison spans a full 24-hour measurement. C1 [Romano, Joao M.] US Army ARDEC, Picatinny Arsenal, NJ 07806 USA. [Rosario, Dalton] Army Res Lab, Adelphi, MD 20783 USA. RP Romano, JM (reprint author), US Army ARDEC, Picatinny Arsenal, NJ 07806 USA. NR 18 TC 0 Z9 0 U1 2 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-036-5 J9 PROC SPIE PY 2014 VL 9099 AR UNSP 90990E DI 10.1117/12.2050398 PG 13 WC Remote Sensing; Optics SC Remote Sensing; Optics GA BB6TX UT WOS:000345017900010 ER PT S AU Karmakar, S Meyers, RE AF Karmakar, Sanjit Meyers, Ronald E. BE Meyers, RE Shih, Y Deacon, KS TI Investigation of a Sub-10 Femtosecond Time Precision Polarized Entangled Photon Source SO QUANTUM COMMUNICATIONS AND QUANTUM IMAGING XII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Quantum Communications and Quantum Imaging XII CY AUG 18-21, 2014 CL San Diego, CA SP SPIE ID PERIODICALLY POLED LINBO3; OPTICAL PARAMETRIC OSCILLATORS; LITHIUM-NIOBATE; 2ND-HARMONIC GENERATION; CONVERSION AB This article reports on a polarized entangled photon source which could provide timing information with sub-10 femtosecond precision. This high precision would confirm the accurate synchronization of two events. Hence, this new source for orthogonally polarized entangled photon pairs would be useful for quantum communications and quantum networking. C1 [Karmakar, Sanjit] Univ Maryland Baltimore Cty, Dept Phys, Baltimore, MD 21250 USA. [Meyers, Ronald E.] US Army Res Lab, Adelphi, MD 20783 USA. RP Karmakar, S (reprint author), Univ Maryland Baltimore Cty, Dept Phys, Baltimore, MD 21250 USA. EM ronald.e.meyers6.civ@mail.mil FU US Army Research Laboratory [W911NF- 11- 2- 0074] FX The authors thank K. Deacon, A. Tunick and Y. H. Shih for helpful discussions. S. Karmakar is a Post- Doctoral Fellow at the US Army Research Laboratory ( W911NF- 11- 2- 0074). NR 15 TC 0 Z9 0 U1 0 U2 0 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-252-9 J9 PROC SPIE PY 2014 VL 9225 AR UNSP 92250K DI 10.1117/12.2066660 PG 6 WC Optics; Imaging Science & Photographic Technology SC Optics; Imaging Science & Photographic Technology GA BB6UC UT WOS:000345025700014 ER PT S AU Meyers, RE Deacon, KS Tunick, A AF Meyers, Ronald E. Deacon, Keith S. Tunick, Arnold BE Meyers, RE Shih, Y Deacon, KS TI Space-Time Quantum Ghost Imaging: Double Beam and Single Beam SO QUANTUM COMMUNICATIONS AND QUANTUM IMAGING XII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Quantum Communications and Quantum Imaging XII CY AUG 18-21, 2014 CL San Diego, CA SP SPIE AB We experimentally demonstrate quantum imaging where the images are stored in both space and time. Quantum images of remote objects are produced with either one or two beams of chaotic laser light and two sensors measuring the reference field and bucket field at different space-time points. Chaotic laser light is produced by laser light passing through rotating ground glass. Experiments were performed in both turbulent and non-turbulent conditions. Interestingly, quantum images are produced using the two sensors of quantum imaging when both single and double beams are implemented in the experimental setup. Also, we observed that the quantum images move depending on the time delay between the sensor measurements. The experiments provide a new testbed for exploring the time and space scale fundamental physics of quantum imaging and suggest new pathways for quantum information storage and processing. The research is applicable to making ghost imaging movies of moving objects and implementation of space-time imaging for enhanced imaging. C1 [Meyers, Ronald E.; Deacon, Keith S.; Tunick, Arnold] US Army Res Lab, Adelphi, MD 20783 USA. RP Meyers, RE (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. EM ronald.e.meyers6.civ@mail.mil NR 11 TC 0 Z9 0 U1 0 U2 2 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-252-9 J9 PROC SPIE PY 2014 VL 9225 AR 922503 DI 10.1117/12.2066658 PG 9 WC Optics; Imaging Science & Photographic Technology SC Optics; Imaging Science & Photographic Technology GA BB6UC UT WOS:000345025700002 ER PT S AU Maurer, T Deaver, D Howell, C Moyer, S Nguyen, O Mueller, G Ryan, D Sia, R Stutzman, R Pasternak, J Bower, K AF Maurer, Tana Deaver, Dawne Howell, Christopher Moyer, Steve Oanh Nguyen Mueller, Greg Ryan, Denise Sia, Rose Stutzman, Richard Pasternak, Joseph Bower, Kraig BE Southern, SO Mentzer, MA RodriguezChavez, I Wotring, VE TI Military target task performance after wavefront-guided (WFG) and wavefront-optimized (WFO) photorefractive keratectomy (PRK) SO SENSING TECHNOLOGIES FOR GLOBAL HEALTH, MILITARY MEDICINE, AND ENVIRONMENTAL MONITORING IV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV CY MAY 05-07, 2014 CL Baltimore, MD SP SPIE DE perception testing; wavefront-guided; WFG; wavefront-optimized; WFO; photorefractive keratectomy; PRK; military task performance; refractive surgery; threshold target identification ID IN-SITU KERATOMILEUSIS; REFRACTIVE SURGERY; CONTRAST SENSITIVITY; VISUAL PERFORMANCE; ABERRATIONS; LASER; MYOPIA; SYMPTOMS; ACUITY; EYES AB Major decisions regarding life and death are routinely made on the modern battlefield, where visual function of the individual soldier can be of critical importance in the decision-making process. Glasses in the combat environment have considerable disadvantages: degradation of short term visual performance can occur as dust and sweat accumulate on lenses during a mission or patrol; long term visual performance can diminish as lenses become increasingly scratched and pitted; during periods of intense physical trauma, glasses can be knocked off the soldier's face and lost or broken. Although refractive surgery offers certain benefits on the battlefield when compared to wearing glasses, it is not without potential disadvantages. As a byproduct of refractive surgery, elevated optical aberrations can be induced, causing decreases in contrast sensitivity and increases in the symptoms of glare, halos, and starbursts. Typically, these symptoms occur under low light level conditions, the same conditions under which most military operations are initiated. With the advent of wavefront aberrometry, we are now seeing correction not only of myopia and astigmatism but of other, smaller optical aberrations that can cause the above symptoms. In collaboration with the Warfighter Refractive Eye Surgery Program and Research Center (WRESP-RC) at Fort Belvoir and Walter Reed National Military Medical Center (WRNMMC), the overall objective of this study is to determine the impact of wavefront guided (WFG) versus wavefront-optimized (WFO) photorefractive keratectomy (PRK) on military task visual performance. Psychophysical perception testing was conducted before and after surgery to measure each participant's performance regarding target detection and identification using thermal imagery. The results are presented here. C1 [Maurer, Tana; Deaver, Dawne; Howell, Christopher; Moyer, Steve; Oanh Nguyen; Mueller, Greg] US Army, RDECOM CERDEC NVESD, 10221 Burbeck Rd, Ft Belvoir, VA 22060 USA. [Ryan, Denise; Sia, Rose] Warfighter Refract Eye Surg Program & Res Ctr, Ft Belvoir, VA USA. [Stutzman, Richard; Pasternak, Joseph] Walter Reed Natl Mil Med Ctr, Ophthalmol Serv, Bethesda, MD USA. [Bower, Kraig] Johns Hopkins Univ, Wilmer Eye Inst, Baltimore, MD USA. RP Maurer, T (reprint author), US Army, RDECOM CERDEC NVESD, 10221 Burbeck Rd, Ft Belvoir, VA 22060 USA. NR 23 TC 0 Z9 0 U1 0 U2 1 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-049-5 J9 PROC SPIE PY 2014 VL 9112 AR UNSP 91120U DI 10.1117/12.2050309 PG 20 WC Engineering, Biomedical; Remote Sensing; Optics; Radiology, Nuclear Medicine & Medical Imaging SC Engineering; Remote Sensing; Optics; Radiology, Nuclear Medicine & Medical Imaging GA BB6WL UT WOS:000345075200010 ER PT S AU Coppock, MB Farrow, B Warner, C Finch, AS Lai, B Sarkes, DA Heath, JR Stratis-Cullum, D AF Coppock, Matthew B. Farrow, Blake Warner, Candice Finch, Amethist S. Lai, Bert Sarkes, Deborah A. Heath, James R. Stratis-Cullum, Dimitra BE Cullum, BM McLamore, ES TI Peptide-based protein capture agents with high affinity, selectivity, and stability as antibody replacements in biodetection assays SO SMART BIOMEDICAL AND PHYSIOLOGICAL SENSOR TECHNOLOGY XI SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Smart Biomedical and Physiological Sensor Technology XI CY MAY 07-09, 2014 CL Baltimore, MD SP SPIE DE PCC agent; peptide-based sensors; biological detection; antibody replacements ID SITU CLICK CHEMISTRY; SINGLE-DOMAIN ANTIBODIES; DISPLAY; BIOSENSORS AB Current biodetection assays that employ monoclonal antibodies as primary capture agents exhibit limited fieldability, shelf life, and performance due to batch-to-batch production variability and restricted thermal stability. In order to improve upon the detection of biological threats in fieldable assays and systems for the Army, we are investigating protein catalyzed capture (PCC) agents as drop-in replacements for the existing antibody technology through iterative in situ click chemistry. The PCC agent oligopeptides are developed against known protein epitopes and can be mass produced using robotic methods. In this work, a PCC agent under development will be discussed. The performance, including affinity, selectivity, and stability of the capture agent technology, is analyzed by immunoprecipitation, western blotting, and ELISA experiments. The oligopeptide demonstrates superb selectivity coupled with high affinity through multi-ligand design, and improved thermal, chemical, and biochemical stability due to non-natural amino acid PCC agent design. C1 [Coppock, Matthew B.; Finch, Amethist S.; Sarkes, Deborah A.; Stratis-Cullum, Dimitra] US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. [Farrow, Blake; Heath, James R.] CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USA. [Warner, Candice] Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD 21010 USA. [Lai, Bert] Indi Mol, Culver City, CA 90230 USA. RP Coppock, MB (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. OI Farrow, Blake/0000-0002-1007-7111 FU Institute for Collaborative Biotechnologies from the U.S. Army Research Office [W911NF09-0001]; U.S. Army Research Laboratory Postdoctoral Fellowship FX This research was funded primarily provided by the Institute for Collaborative Biotechnologies through grant W911NF09-0001 from the U.S. Army Research Office. Research is supported in part by appointments (M.B.C.) to the U.S. Army Research Laboratory Postdoctoral Fellowship Program administered by the Oak Ridge Associated Universities through a contract with the U.S. Army Research Laboratory. The content of the information does not necessarily reflect the position or the policy of the Government, and no official endorsement should be inferred. The following reagents were obtained through the NIH Biodefense and Emerging Infections Research Resources Repository, NIAID, NIH. Anthrax Protective Antigen (PA), recombinant from E. coli, NR-3780. NR 15 TC 0 Z9 0 U1 0 U2 6 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-044-0 J9 PROC SPIE PY 2014 VL 9107 AR UNSP 910711 DI 10.1117/12.2052542 PG 6 WC Engineering, Biomedical; Instruments & Instrumentation; Optics SC Engineering; Instruments & Instrumentation; Optics GA BB6WC UT WOS:000345067200023 ER PT J AU Harrison, SA Chalasani, NP Lawitz, E Marri, S Noureddin, M Sanyal, AJ Schiano, TD Siddiqui, MS Neuschwander-Tetri, BA Traber, PG AF Harrison, Stephen A. Chalasani, Naga P. Lawitz, Eric Marri, Smitha Noureddin, Mazen Sanyal, Arun J. Schiano, Thomas D. Siddiqui, Mohammad S. Neuschwander-Tetri, Brent A. Traber, Peter G. TI Early phase 1 clinical trial results of GR-MD-02, a galectin-3 inhibitor, in patients having non-alcoholic steatohepatitis (NASH) with advanced fibrosis SO HEPATOLOGY LA English DT Meeting Abstract CT 65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases CY NOV 07-11, 2014 CL Boston, MA SP Amer Assoc Study Liver Dis C1 [Harrison, Stephen A.] Brooke Army Med Ctr, San Antonio, TX USA. [Chalasani, Naga P.; Marri, Smitha] Indiana Univ Sch Med, Indianapolis, IN 46202 USA. [Lawitz, Eric] Univ Texas Hlth Sci Ctr San Antonio, Texas Liver Inst, San Antonio, TX 78229 USA. [Noureddin, Mazen] Univ So Calif, Los Angeles, CA USA. [Sanyal, Arun J.; Siddiqui, Mohammad S.] VCU Med Ctr, Richmond, VA USA. [Schiano, Thomas D.] Icahn Sch Med Mt Sinai, New York, NY 10029 USA. [Neuschwander-Tetri, Brent A.] St Louis Univ, St Louis, MO 63103 USA. [Traber, Peter G.] Galectin Therapeut, Norcross, GA USA. [Traber, Peter G.] Emory Univ, Sch Med, Atlanta, GA USA. NR 0 TC 3 Z9 3 U1 0 U2 2 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0270-9139 EI 1527-3350 J9 HEPATOLOGY JI Hepatology PY 2014 VL 60 SU 1 SI SI MA 57 BP 225A EP 226A PG 2 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA AS8EW UT WOS:000344483800058 ER PT J AU Kim, WR Loomba, R Lal, P Schall, REA Johnson, AD Bornstein, JD Subramanian, M McHutchison, JG Harrison, SA Sanyal, AJ AF Kim, W. Ray Loomba, Rohit Lal, Preeti Schall, Raul E. Aguilar Johnson, Ann D. Bornstein, Jeffrey D. Subramanian, Mani McHutchison, John G. Harrison, Stephen A. Sanyal, Arun J. TI Serum Lysyl Oxidase Like 2 (sLOXL2) Levels Correlate with Ishak Fibrosis Score and Decrease with Treatment with Tenofovir Disoproxil Fumarate (TDF) in Patients with Chronic Hepatitis B (CHB) SO HEPATOLOGY LA English DT Meeting Abstract CT 65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases CY NOV 07-11, 2014 CL Boston, MA SP Amer Assoc Study Liver Dis C1 [Kim, W. Ray] Stanford, Palo Alto, CA USA. [Loomba, Rohit] Univ Calif San Diego, San Diego, CA 92103 USA. [Lal, Preeti; Schall, Raul E. Aguilar; Johnson, Ann D.; Bornstein, Jeffrey D.; Subramanian, Mani; McHutchison, John G.] Gilead Sci Inc, Foster City, CA 94404 USA. [Harrison, Stephen A.] Brooke Army Med Ctr, Ft Sam Houston, TX 78234 USA. [Sanyal, Arun J.] Virginia Commonwealth Univ, Sch Med, Richmond, VA USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0270-9139 EI 1527-3350 J9 HEPATOLOGY JI Hepatology PY 2014 VL 60 SU 1 SI SI MA 439 BP 416A EP 417A PG 2 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA AS8EW UT WOS:000344483801371 ER PT J AU Lominadze, Z Harrison, SA Charlton, M Loomba, R Neuschwander-Tetri, BA Caldwell, SH Kowdley, KV Rinella, ME AF Lominadze, Zurabi Harrison, Stephen A. Charlton, Michael Loomba, Rohit Neuschwander-Tetri, Brent A. Caldwell, Stephen H. Kowdley, Kris V. Rinella, Mary E. TI Survey of Diagnostic and Treatment Patterns of NAFLD and NASH in the United States: Real Life Practices Differ From Published Guidelines SO HEPATOLOGY LA English DT Meeting Abstract CT 65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases CY NOV 07-11, 2014 CL Boston, MA SP Amer Assoc Study Liver Dis C1 [Lominadze, Zurabi; Rinella, Mary E.] Northwestern Univ, Chicago, IL 60611 USA. [Harrison, Stephen A.] Brooke Army Med Ctr, San Antonio, TX USA. [Charlton, Michael] Intermt Med Ctr, Murray, UT USA. [Loomba, Rohit] Univ Calif San Diego, San Diego, CA 92103 USA. [Neuschwander-Tetri, Brent A.] St Louis Univ, St Louis, MO 63103 USA. [Caldwell, Stephen H.] Univ Virginia, Charlottesville, VA USA. [Kowdley, Kris V.] Virginia Mason Med Ctr, Seattle, WA 98101 USA. [Rinella, Mary E.] Northwestern Univ, Div Gastroenterol & Hepatol, Chicago, IL 60611 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0270-9139 EI 1527-3350 J9 HEPATOLOGY JI Hepatology PY 2014 VL 60 SU 1 SI SI MA 838 BP 604A EP 605A PG 2 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA AS8EW UT WOS:000344483802334 ER PT J AU Harrison, SA Okada, SY Su, CA Paulson, M Bornstein, JD Sanyal, AJ AF Harrison, Stephen A. Okada, Sheldon Y. Su, Cathy A. Paulson, Matthew Bornstein, Jeffrey D. Sanyal, Arun J. TI US Physician Survey of Current Practices in the Diagnosis and Treatment of Nonalcoholic Steatohepatitis (NASH) SO HEPATOLOGY LA English DT Meeting Abstract CT 65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases CY NOV 07-11, 2014 CL Boston, MA SP Amer Assoc Study Liver Dis C1 [Harrison, Stephen A.] Brooke Army Med Ctr, Ft Sam Houston, TX 78234 USA. [Okada, Sheldon Y.; Su, Cathy A.; Paulson, Matthew; Bornstein, Jeffrey D.] Gilead Sci Inc, Foster City, CA 94404 USA. [Sanyal, Arun J.] Virginia Commonwealth Univ, Sch Med, Richmond, VA USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0270-9139 EI 1527-3350 J9 HEPATOLOGY JI Hepatology PY 2014 VL 60 SU 1 SI SI MA 890 BP 630A EP 630A PG 1 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA AS8EW UT WOS:000344483802386 ER PT B AU Smith, TJ AF Smith, Theresa J. BE Foster, KA TI Clostridium botulinum Genomes and Genetic Diversity SO MOLECULAR ASPECTS OF BOTULINUM NEUROTOXIN, VOL 4 SE Current Topics in Neurotoxicity LA English DT Article; Book Chapter DE Botulinum neurotoxin; C. botulinum groups; 16s rrn genes; BoNT-producing clostridial species; C. botulinum genome; Genomic islands; Pathogenicity islands; Gene clusters; Chromosomal synteny; Proteolytic strains; Nonproteolytic strains; Clostridial genomes; Gene clusters; Neurotoxin serotypes; Toxin subtypes; Recombination ID NEUROTOXIN TYPE-A; NUCLEOTIDE-SEQUENCE ANALYSIS; AMINO-ACID-SEQUENCE; BARATII TYPE-F; INFANT BOTULISM; B BOTULINUS; STRUCTURAL GENE; ENCODING GENE; UNITED-STATES; COMPLEX GENES AB Botulinum neurotoxins (BoNTs) are produced by multiple members of the clostridial genus. Seven neurotoxin serotypes and 35 distinct toxin subtypes/genetic variants have been identified based on immunological characteristics and sequence diversity. Analysis of neurotoxin and genome sequences provides evidence that horizontal gene transfer may be a primary mechanism for the movement of neurotoxin genes within these bacteria and that genetic mobility among different bacterial species is facilitated by their phage or plasmid locations. Bacterial and neurotoxin relationships are described based on historic parameters and recent genomic sequencing efforts. Examination of the factors that provide genetic mobility for neurotoxin genes contributes to understanding the diversity resident in the neurotoxins, the toxin complexes and the bacteria that produce them. C1 US Army Med Res Inst Infect Dis, Integrated Toxicol, Ft Detrick, MD 21702 USA. RP Smith, TJ (reprint author), US Army Med Res Inst Infect Dis, Integrated Toxicol, Ft Detrick, MD 21702 USA. EM theresa.j.smith.civ@mail.mil NR 109 TC 1 Z9 1 U1 0 U2 1 PU SPRINGER PI NEW YORK PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES BN 978-1-4614-9454-6; 978-1-4614-9453-9 J9 CURR TOP NEUROTOX PY 2014 VL 4 BP 207 EP 228 DI 10.1007/978-1-4614-9454-6_10 D2 10.1007/978-1-4614-9454-6 PG 22 WC Biochemistry & Molecular Biology; Neurosciences; Toxicology SC Biochemistry & Molecular Biology; Neurosciences & Neurology; Toxicology GA BB6GC UT WOS:000344751500010 ER PT B AU Adler, M Gul, N Eitzen, E Oyler, G Molles, B AF Adler, Michael Gul, Nizamettin Eitzen, Edward Oyler, George Molles, Brian BE Foster, KA TI Prevention and Treatment of Botulism SO MOLECULAR ASPECTS OF BOTULINUM NEUROTOXIN, VOL 4 SE Current Topics in Neurotoxicity LA English DT Article; Book Chapter DE Antitoxin; Bioterrorism; Botulinum neurotoxin; Botulism; Metalloprotease inhibitors; Vaccine ID NEUROTOXIN TYPE-A; TOXIN TYPE-A; NERVE-HEMIDIAPHRAGM PREPARATIONS; RECOMBINANT VACCINE CANDIDATE; NUCLEOTIDE-SEQUENCE ANALYSIS; DEPENDENT KINASE INHIBITOR; BIOLOGICAL WARFARE AGENTS; SMALL-MOLECULE INHIBITORS; SYNAPTIC PROTEIN SNAP-25; SELICICLIB R-ROSCOVITINE AB Concerns regarding botulinum neurotoxins (BoNTs) as biowarfare and bioterrorist agents have generated interest in developing medical countermeasures for protection against the neurotoxins. Efforts have focused on improvements in the available vaccines and antisera and de novo discovery of pharmacological inhibitors of toxin action. This chapter reviews the various approaches taken to develop next-generation vaccines, antitoxins and pharmacological treatments against intoxication by the BoNTs. The historical progression, current status and future trends are described. C1 [Adler, Michael; Gul, Nizamettin; Molles, Brian] US Army Med Res Inst Chem Def, Neurobehav Toxicol Branch, Analyt Toxicol Div, Aberdeen Proving Ground, MD 21010 USA. [Eitzen, Edward] Martin Blanck & Associates, Med Devices Ind, Falls Church, VA 22041 USA. [Oyler, George] Synapt Res LLC, Catonsville, MD 21218 USA. RP Adler, M (reprint author), US Army Med Res Inst Chem Def, Neurobehav Toxicol Branch, Analyt Toxicol Div, Aberdeen Proving Ground, MD 21010 USA. EM michael.adler2.civ@mail.mil NR 272 TC 2 Z9 2 U1 1 U2 3 PU SPRINGER PI NEW YORK PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES BN 978-1-4614-9454-6; 978-1-4614-9453-9 J9 CURR TOP NEUROTOX PY 2014 VL 4 BP 291 EP 342 DI 10.1007/978-1-4614-9454-6_13 D2 10.1007/978-1-4614-9454-6 PG 52 WC Biochemistry & Molecular Biology; Neurosciences; Toxicology SC Biochemistry & Molecular Biology; Neurosciences & Neurology; Toxicology GA BB6GC UT WOS:000344751500013 ER PT S AU Chang, YC Zhu, WB Chao, JH Yin, SZ Hoffman, RC Mott, AG Luo, C AF Chang, Yun-Ching Zhu, Wenbin Chao, Ju-Hung Yin, Shizhuo Hoffman, Robert C. Mott, Andrew G. Luo, Claire BE Yin, S Guo, R TI Super broadband ultrafast waveguide switches based on dynamic waveguiding effect SO PHOTONIC FIBER AND CRYSTAL DEVICES: ADVANCES IN MATERIALS AND INNOVATIONS IN DEVICE APPLICATIONS VIII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Photonic Fiber and Crystal Devices - Advances in Materials and Innovations in Device Applications VIII CY AUG 17-18, 2014 CL San Diego, CA SP SPIE DE Electro-optical materials; KTN; optical waveguide; optical switch; dynamic switch; nanodisordered KTN; optics networks; data centers ID TANTALATE-NIOBATE CRYSTALS; PHOTONIC NETWORKS; ON-CHIP AB In this paper, a new type of waveguide switch-field induced dynamic optical waveguide switch is presented. The switching mechanism is based on electric-field induced dynamic waveguiding effect in nanodisordered potassium tantalate niobate (KTN) crystals. By applying an electric field at different locations, different waveguide paths are created, which result in different output locations. The major advantages of this unique optical switch are broad bandwidth, covering the entire 1300 nm - 1600 nm fiber optic communication window, and ultrafast switching speed (on the order of nanosecond), which can be very useful for next generation optical networks such as the one used in data center networks. C1 [Chang, Yun-Ching; Zhu, Wenbin; Chao, Ju-Hung; Yin, Shizhuo] Penn State Univ, Dept Elect Engn, University Pk, PA 16802 USA. [Hoffman, Robert C.; Mott, Andrew G.] US Army, Res Lab, Adelphi, MD 20783 USA. [Luo, Claire] Gen Opto Solut LLC, State Coll, PA 16803 USA. RP Chang, YC (reprint author), Penn State Univ, Dept Elect Engn, University Pk, PA 16802 USA. EM sxy105@psu.edu FU National Science Foundation EAGER program; Army Research Laboratory [W911NF-092-0016] FX The portion of the work related to dynamic waveguiding effect enabled switch was partially supported by the National Science Foundation EAGER program. The portion of the work related to nanodisorderd KTN crystals was partially sponsored by the Army Research Laboratory and was accomplished under Cooperative Agreement Number W911NF-092-0016. The views and conclusions contained in this document are those of the authors and should not be interpreted as representing the official policies, either expressed or implied, of the Army Research Laboratory or the U. S. Government. The U. S. Government is authorized to reproduce and distribute reprints for Government purposes notwithstanding any copyright notation heron. NR 10 TC 0 Z9 0 U1 0 U2 2 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-227-7 J9 PROC SPIE PY 2014 VL 9200 AR UNSP 92000X DI 10.1117/12.2065590 PG 7 WC Materials Science, Multidisciplinary; Optics; Physics, Applied SC Materials Science; Optics; Physics GA BB6AZ UT WOS:000344550200020 ER PT S AU Yin, S Ruffin, P Brantley, C Edwards, E Luo, C AF Yin, Stuart (Shizhuo) Ruffin, Paul Brantley, Christina Edwards, Eugene Luo, Claire BE Yin, S Guo, R TI Mid-IR supercontinuum generation and applications: a review SO PHOTONIC FIBER AND CRYSTAL DEVICES: ADVANCES IN MATERIALS AND INNOVATIONS IN DEVICE APPLICATIONS VIII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Photonic Fiber and Crystal Devices - Advances in Materials and Innovations in Device Applications VIII CY AUG 17-18, 2014 CL San Diego, CA SP SPIE DE Supercontinuum; Mid-Infrared (IR); nonlinear fiber optics; chemical analysis; spectral analysis; smart pattern recognition; IR crystal fiber ID CRYSTAL SAPPHIRE FIBERS; LASER; POWER AB In this paper, a review on mid-IR supercontinuum generation (SCG) and its applications is presented. First, the physical mechanism of the supercontinuum generation in IR crystal fiber is introduced. Second, the recent progress on IR single crystal fiber, in particular ultrathin core double cladding IR single crystal fiber is described. Third, the transmission characteristics of mid-IR crystal fiber is illustrated. Fourth, the mid-IR supercontinuum generation in IR single crystal fiber is presented. Finally, the application of IR supercontinuum for smart target recognition is illustrated C1 [Yin, Stuart (Shizhuo)] Penn State Univ, Dept Elect Engn, University Pk, PA 16802 USA. [Ruffin, Paul; Brantley, Christina; Edwards, Eugene] US Army, Aviat & Missile Res Dev & Engn Ctr, Redstone Arsenal, AL 35898 USA. [Luo, Claire] Gen Opto Solut LLC, State Coll, PA 16803 USA. RP Yin, S (reprint author), Penn State Univ, Dept Elect Engn, University Pk, PA 16802 USA. RI Chen, Ru/A-5105-2015 FU Army project FX Authors acknowledge the partial support from an Army project. Also, the views expressed herein are those of the author and do not reflect the official policy or position of the Department of the Army, Department of Defense, or the U. S. Government." NR 14 TC 0 Z9 0 U1 3 U2 9 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-227-7 J9 PROC SPIE PY 2014 VL 9200 AR UNSP 92000U DI 10.1117/12.2065589 PG 12 WC Materials Science, Multidisciplinary; Optics; Physics, Applied SC Materials Science; Optics; Physics GA BB6AZ UT WOS:000344550200017 ER PT J AU Gray, P Cox, JD AF Gray, Patrick Cox, John D. BE Gray, P Cox, JD TI Introduction: rethinking Shakespeare and ethics SO SHAKESPEARE AND RENAISSANCE ETHICS LA English DT Editorial Material; Book Chapter ID HAMLET; NIETZSCHE; MORALITY; ENGLISH; HISTORY C1 [Gray, Patrick] Univ Durham, Dept English Studies, Durham DH1 3HP, England. [Gray, Patrick] Providence Coll, Deep Springs Coll, West Point, NY USA. [Gray, Patrick] US Mil Acad, West Point, NY USA. [Cox, John D.] Hope Coll, Holland, MI USA. RP Gray, P (reprint author), Univ Durham, Dept English Studies, Durham DH1 3HP, England. NR 149 TC 0 Z9 0 U1 0 U2 0 PU CAMBRIDGE UNIV PRESS PI CAMBRIDGE PA THE PITT BUILDING, TRUMPINGTON ST, CAMBRIDGE CB2 1RP, CAMBS, ENGLAND BN 978-1-107-07193-3 PY 2014 BP 1 EP 34 D2 10.1017/CBO9781107786158 PG 34 WC Literary Theory & Criticism; Literature, British Isles SC Literature GA BB5YI UT WOS:000344234400002 ER PT J AU Gray, P AF Gray, Patrick BE Gray, P Cox, JD TI "HIDE THY SELFE": Montaigne, Hamlet, and Epicurean ethics SO SHAKESPEARE AND RENAISSANCE ETHICS LA English DT Article; Book Chapter C1 [Gray, Patrick] Univ Durham, Dept English Studies, Durham DH1 3HP, England. [Gray, Patrick] Providence Coll, Deep Springs Coll, West Point, NY USA. [Gray, Patrick] US Mil Acad, West Point, NY USA. RP Gray, P (reprint author), Univ Durham, Dept English Studies, Durham DH1 3HP, England. NR 60 TC 0 Z9 0 U1 0 U2 0 PU CAMBRIDGE UNIV PRESS PI CAMBRIDGE PA THE PITT BUILDING, TRUMPINGTON ST, CAMBRIDGE CB2 1RP, CAMBS, ENGLAND BN 978-1-107-07193-3 PY 2014 BP 213 EP 236 D2 10.1017/CBO9781107786158 PG 24 WC Literary Theory & Criticism; Literature, British Isles SC Literature GA BB5YI UT WOS:000344234400011 ER PT B AU Williams, GT Barrett, MB Graham, CH AF Williams, George T. Barrett, Michael B. Graham, Charles H. BE Eliason, G Eliason, T Samide, J Patrick, J TI CAREER COUNSELING AND DEVELOPMENTAL PATHWAYS ACROSS THE LIFESPAN IN THE MILITARY SO CAREER DEVELOPMENT ACROSS THE LIFESPAN: COUNSELING FOR COMMUNITY, SCHOOLS, HIGHER EDUCATION, AND BEYOND SE Issues in Career Development LA English DT Article; Book Chapter C1 [Williams, George T.] The Citadel, Sch Educ, Charleston, SC 29409 USA. [Williams, George T.] South Carolina Counseling Assoc, Myrtle Beach, SC USA. [Williams, George T.] South Carolina Career Dev Assoc, Myrtle Beach, SC USA. [Barrett, Michael B.; Graham, Charles H.] The Citadel, Charleston, SC 29409 USA. [Barrett, Michael B.] US Army Reserve, Ft Bragg, NC USA. RP Williams, GT (reprint author), The Citadel, Sch Educ, Charleston, SC 29409 USA. NR 2 TC 0 Z9 0 U1 0 U2 0 PU INFORMATION AGE PUBLISHING-IAP PI CHARLOTTE PA PO BOX 79049, CHARLOTTE, NC 28271-7047 USA BN 978-1-62396-547-1; 978-1-62396-548-8 J9 ISS CAREER DEV PY 2014 BP 713 EP 728 PG 16 WC Education & Educational Research; Psychology, Applied SC Education & Educational Research; Psychology GA BB3VG UT WOS:000343068400032 ER PT S AU D'Souza, AI Robinson, E Ionescu, AC Okerlund, D de Lyon, TJ Rajavel, RD Sharifi, H Dhar, NK Wijewarnasuriya, PS Grein, C AF D'Souza, A. I. Robinson, E. Ionescu, A. C. Okerlund, D. de Lyon, T. J. Rajavel, R. D. Sharifi, H. Dhar, N. K. Wijewarnasuriya, P. S. Grein, C. BE Dhar, NK Dutta, AK TI InAsSb Detector & FPA Data and Analysis SO IMAGE SENSING TECHNOLOGIES: MATERIALS, DEVICES, SYSTEMS, AND APPLICATIONS SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Image Sensing Technologies - Materials, Devices, Systems, and Applications CY MAY 07-08, 2014 CL Baltimore, MD SP SPIE AB InAsSb material with a cutoff wavelength in the 5 mu m range has been grown on GaAs substrates. The MWIR InAsSb detector arrays were fabricated and hybridized to fanouts and ROICs to permit measurement of the electrical and optical properties of detectors. Detector arrays were fabricated in a 1024 x 1024 format on an 18 mu m pitch. A fanout was utilized to directly acquire data from a set of selected detectors without an intervening read out integrating circuit (ROIC). Variable temperature J(dark) vs V-d measurements have been made with the dark current density similar to 10(-5) A/cm(2) at 150 K. The external QE measured using a narrow band filter centered at similar to 4 mu m had values in the 65 - 70 % range. Since the detectors were illuminated through a GaAs substrate which has a reflectance of 29%, the internal QE is greater than 90 %. A 1024 x 1024 ROIC on an 18 mu m pitch was also designed and fabricated to interface with the barrier detectors. The ROIC operates at 30 Hz frame rate and has a well capacity of 20.7 M electrons. QE at 150 K for a 1024 x 1024 detector array hybridized to a ROIC had a median D* at 150 K under a flux of 1.07 x 10(15) ph/(cm(2)/s was 1.2 x 10(11) cm Hz(1/2)/W. The NEdT was 44 mK and imagery was obtained at 150 K using an f/2.3 MWIR lens. C1 [D'Souza, A. I.; Robinson, E.; Ionescu, A. C.; Okerlund, D.] DRS Sensors & Targeting Syst, 10600 Valley View St, Cypress, CA 90630 USA. [Dhar, N. K.] DARPA, MTO, Arlington, VA 22203 USA. [Wijewarnasuriya, P. S.] US Army Res Lab, Adelphi, MD 20783 USA. [Grein, C.] Univ Illinois, Chicago, IL 60607 USA. RP D'Souza, AI (reprint author), DRS Sensors & Targeting Syst, 10600 Valley View St, Cypress, CA 90630 USA. FU DARPA [N66604- 09- C- 3652] FX This work was supported by DARPA under contract N66604- 09- C- 3652 (Dr. Nibir Dhar, DARPA Program Manager). However, " The views expressed are those of the author and do not reflect the official policy or position of the Department of Defense or the U. S. Government." This is in accordance with DoDI 5230.29, January 8, 2009. The paper is approved for public release, distribution unlimited. Special thanks to Dr. Roger DeWames for help in analyzing the data. NR 4 TC 0 Z9 0 U1 0 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-037-2 J9 PROC SPIE PY 2014 VL 9100 AR UNSP 91000B DI 10.1117/12.2058150 PG 9 WC Engineering, Electrical & Electronic; Optics SC Engineering; Optics GA BB5PZ UT WOS:000344018800006 ER PT S AU Gupta, N AF Gupta, Neelam BE Dhar, NK Dutta, AK TI Materials for Imaging Acousto-Optic Tunable Filters SO IMAGE SENSING TECHNOLOGIES: MATERIALS, DEVICES, SYSTEMS, AND APPLICATIONS SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Image Sensing Technologies - Materials, Devices, Systems, and Applications CY MAY 07-08, 2014 CL Baltimore, MD SP SPIE DE Hyperspectral; imager; acousto-optic tunable filter; AOTF; birefringent material; UV to LWIR; broadband; KDP; MgF2; TeO2; TAS; Te; mercurous halides; Hg2Br2 ID TELECENTRIC CONFOCAL OPTICS; DIOXIDE SINGLE-CRYSTAL; PERFORMANCE; ULTRAVIOLET; IMAGER; SPECTROMETER; REGION; KDP AB Research and development of robust compact hyperspectral imagers that can acquire both spectral and spatial features from a scene of interest is of utmost importance for standoff detection of targets as well as chemical and biological agents and backgrounds. Hyperspectral imagers can acquire images with a large number of narrow spectral bands and take advantage of the characteristic spectral signatures of different materials making up the scene. At the Army Research Laboratory (ARL), we are developing hyperspectral imagers based on acousto-optic tunable filters (AOTFs) that can provide adaptive no-moving-parts imagers from the ultraviolet (UV) to the long wave infrared (LWIR) to acquire a two-dimensional spectral image and build up a two-dimensional image cube as a function of time instead of using traditional grating or prism based approach that requires relative motion between sensor and scene. Here, we will review the development of different imaging AOTFs operating from the UV to the LWIR based on a variety of birefringent materials and include the spectral imaging carried out with these filters including both with single and double piezoelectric transducers. We will also include the theoretical background needed to carry out the filter design and discuss development of mercurous halide crystals that can be used to develop AOTFs operating over a wide spectral region from the visible to the LWIR. C1 US Army Res Lab, Adelphi, MD 20783 USA. RP Gupta, N (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 38 TC 2 Z9 2 U1 1 U2 7 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-037-2 J9 PROC SPIE PY 2014 VL 9100 AR 91000C DI 10.1117/12.2054050 PG 10 WC Engineering, Electrical & Electronic; Optics SC Engineering; Optics GA BB5PZ UT WOS:000344018800007 ER PT S AU Sood, AK Welser, RE Puri, YR Dhar, NK Polla, DL Wijewarnasuriya, P Dubey, M AF Sood, Ashok K. Welser, Roger E. Puri, Yash R. Dhar, Nibir K. Polla, Dennis L. Wijewarnasuriya, Priyalal Dubey, Madan BE Dhar, NK Dutta, AK TI Nanostructured Detector Technologies for Optical Sensing Applications SO IMAGE SENSING TECHNOLOGIES: MATERIALS, DEVICES, SYSTEMS, AND APPLICATIONS SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Image Sensing Technologies - Materials, Devices, Systems, and Applications CY MAY 07-08, 2014 CL Baltimore, MD SP SPIE ID VAPOR-DEPOSITION MOCVD; ZNO NANOWIRES; GROWTH C1 [Sood, Ashok K.; Welser, Roger E.; Puri, Yash R.] Magnolia Opt Technol Inc, 52-B Cummings Pk,Suite 314, Woburn, MA 01801 USA. [Dhar, Nibir K.] Def Adv Project Agcy, Arlington, VA 22203 USA. [Polla, Dennis L.] Univ Minnesota, Coll Sci & Engn, Minneapolis, MN 55455 USA. [Wijewarnasuriya, Priyalal; Dubey, Madan] Army Res Lab, Adelphi, MD 20783 USA. RP Sood, AK (reprint author), Magnolia Opt Technol Inc, 52-B Cummings Pk,Suite 314, Woburn, MA 01801 USA. FU DARPA; Navy SBIR FX The Magnolia authors gratefully acknowledge the DARPA and Navy SBIR Program support for development of nanotechnology based EO/ IR detector technology for optical sensor applications. NR 26 TC 0 Z9 0 U1 0 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-037-2 J9 PROC SPIE PY 2014 VL 9100 AR UNSP 91000N DI 10.1117/12.2058152 PG 14 WC Engineering, Electrical & Electronic; Optics SC Engineering; Optics GA BB5PZ UT WOS:000344018800015 ER PT S AU Velicu, S Buurma, C Bergeson, JD Kim, TS Kubby, J Gupta, N AF Velicu, S. Buurma, C. Bergeson, J. D. Kim, Tae Sung Kubby, J. Gupta, N. BE Dhar, NK Dutta, AK TI Miniaturized Imaging Spectrometer Based on Fabry-Perot MOEMS filters and HgCdTe Infrared Focal Plane Arrays SO IMAGE SENSING TECHNOLOGIES: MATERIALS, DEVICES, SYSTEMS, AND APPLICATIONS SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Image Sensing Technologies - Materials, Devices, Systems, and Applications CY MAY 07-08, 2014 CL Baltimore, MD SP SPIE DE Infrared; hyperspectral; detector; focal plane array; Fabry-Perot filter; distributed Bragg reflector; HgCdTe; micro-electro-mechanical-systems AB Imaging spectrometry can be utilized in the midwave infrared (MWIR) and long wave infrared (LWIR) bands to detect, identify and map complex chemical agents based on their rotational and vibrational emission spectra. Hyperspectral datasets are typically obtained using grating or Fourier transform spectrometers to separate the incoming light into spectral bands. At present, these spectrometers are large, cumbersome, slow and expensive, and their resolution is limited by bulky mechanical components such as mirrors and gratings. As such, low-cost, miniaturized imaging spectrometers are of great interest. Microfabrication of micro-electro-mechanical-systems (MEMS)-based components opens the door for producing low-cost, reliable optical systems. We present here our work on developing a miniaturized IR imaging spectrometer by coupling a mercury cadmium telluride (HgCdTe)-based infrared focal plane array (FPA) with a MEMS-based Fabry-Perot filter (FPF). The two membranes are fabricated from silicon-on-insulator (SOI) wafers using bulk micromachining technology. The fixed membrane is a standard silicon membrane, fabricated using back etching processes. The movable membrane is implemented as an X-beam structure to improve mechanical stability. The geometries of the distributed Bragg reflector (DBR)-based tunable FPFs are modeled to achieve the desired spectral resolution and wavelength range. Additionally, acceptable fabrication tolerances are determined by modeling the spectral performance of the FPFs as a function of DBR surface roughness and membrane curvature. These fabrication non-idealities are then mitigated by developing an optimized DBR process flow yielding high-performance FPF cavities. Zinc Sulfide (ZnS) and Germanium (Ge) are chosen as the low and the high index materials, respectively, and are deposited using an electron beam process. Simulations are presented showing the impact of these changes and non-idealities in both a device and systems level. C1 [Velicu, S.; Buurma, C.; Bergeson, J. D.; Kim, Tae Sung] EPIR Technol Inc, 590 Terr Dr Unit B, Bolingbrook, IL 60440 USA. [Kim, Tae Sung; Kubby, J.] Univ Calif Santa Cruz, Dept Elect Engn, Santa Cruz, CA 95064 USA. [Gupta, N.] US Army Res Lab, Adelphi, MD 20783 USA. RP Velicu, S (reprint author), EPIR Technol Inc, 590 Terr Dr Unit B, Bolingbrook, IL 60440 USA. NR 7 TC 0 Z9 0 U1 2 U2 6 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-037-2 J9 PROC SPIE PY 2014 VL 9100 AR UNSP 91000F DI 10.1117/12.2053902 PG 15 WC Engineering, Electrical & Electronic; Optics SC Engineering; Optics GA BB5PZ UT WOS:000344018800008 ER PT S AU Bayya, S Gibson, D Nuygen, V Fleet, E Vizgaitiz, J Sanghera, J AF Bayya, Shyam Gibson, Daniel Vinh Nuygen Fleet, Erin Vizgaitiz, Jay Sanghera, Jasbinder BE Andresen, BF Fulop, GF Hanson, CM Norton, PR TI Multispectral Optics Designs Using Expanded Glass Map SO INFRARED TECHNOLOGY AND APPLICATIONS XL SE Proceedings of SPIE LA English DT Proceedings Paper CT 40th Conference on Infrared Technology and Applications CY MAY 04-08, 2014 CL Baltimore, MD SP SPIE DE SWIR; MWIR; LWIR; MILTRAN; IR glass; multispectral optics AB We report new materials that transmit from 0.9 to > 14 mu m in wavelength and fill up the glass map for multispectral optics having refractive index from 2.38 to 3.17. They show a large spread in dispersion ( Abbe number) and offer some unique solutions for multispectral optics designs. The new IR glasses can be easily molded and also fused together to make bonded doublets. We present the benefits of these new materials through dual-band optics designs and compare to designs using currently available crystalline materials. C1 [Bayya, Shyam; Gibson, Daniel; Vinh Nuygen; Fleet, Erin; Sanghera, Jasbinder] Naval Res Lab, Code 5620, Washington, DC 20375 USA. [Vizgaitiz, Jay] US Army RDECOM CERDEC NVESD, Ft Belvoir, VA USA. RP Bayya, S (reprint author), Naval Res Lab, Code 5620, Washington, DC 20375 USA. NR 9 TC 2 Z9 2 U1 0 U2 2 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-007-5 J9 PROC SPIE PY 2014 VL 9070 AR UNSP 90702G DI 10.1117/12.2050624 PG 12 WC Engineering, Electrical & Electronic; Optics; Physics, Applied SC Engineering; Optics; Physics GA BB5UG UT WOS:000344113500084 ER PT S AU Bommena, R Bergeson, JD Kodama, R Zhao, J Ketharanathan, S Schaake, H Shih, H Velicu, S Aqariden, F Wijewarnasuriya, PS Dhar, NK AF Bommena, R. Bergeson, J. D. Kodama, R. Zhao, J. Ketharanathan, S. Schaake, H. Shih, H. Velicu, S. Aqariden, F. Wijewarnasuriya, P. S. Dhar, N. K. BE Andresen, BF Fulop, GF Hanson, CM Norton, PR TI HIGH PERFORMANCE SWIR HgCdTe FPA DEVELOPMENT ON SILICON SUBSTRATES SO INFRARED TECHNOLOGY AND APPLICATIONS XL SE Proceedings of SPIE LA English DT Proceedings Paper CT 40th Conference on Infrared Technology and Applications CY MAY 04-08, 2014 CL Baltimore, MD SP SPIE DE MBE; HgCdTe; SWIR; Silicon; CdTe; Dark Current; Quantum Efficiency; FPA AB We report the development of high performance low cost SWIR infrared detectors from MBE-grown HgCdTe on 3-inch CdTe-buffered silicon substrates. The experimental findings demonstrate that despite the large lattice mismatch between HgCdTe and Si substrate, the materials and detector performances are sufficiently better than those reported for III-V mixed crystals. High minority carrier lifetime of the order 3 mu s at room temperature was measured on the as grown material. Photodetectors fabricated from this material produced low dark current densities on the order of 10(-6) A/cm(2) and 10(-3) A/cm(2) at 200K and 300K. Quantum efficiency exceeding 70% at 2.0 mu m, without antireflective coating, was measured on single element detectors. Further, 320 X 256, 30 mu m pitch FPA's have been fabricated with this HgCdTe on Si material and dark current operability of similar to 99.5% (mean dark current of 30 pA/Pixel) at 200K has been demonstrated. C1 [Bommena, R.; Bergeson, J. D.; Kodama, R.; Zhao, J.; Ketharanathan, S.; Schaake, H.; Shih, H.; Velicu, S.; Aqariden, F.] EPIR Technol Inc, Bolingbrook, IL 60440 USA. [Wijewarnasuriya, P. S.] Army Res Lab, Adelphi, MD USA. [Dhar, N. K.] DARPA, MTO, Arlington, VA USA. RP Bommena, R (reprint author), EPIR Technol Inc, Bolingbrook, IL 60440 USA. FU DARPA FX This work was performed with funding support from DARPA and we would like to acknowledge the technical support from Army Research Laboratory for characterization of material and devices. NR 10 TC 5 Z9 5 U1 2 U2 6 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-007-5 J9 PROC SPIE PY 2014 VL 9070 AR UNSP 907009 DI 10.1117/12.2053020 PG 12 WC Engineering, Electrical & Electronic; Optics; Physics, Applied SC Engineering; Optics; Physics GA BB5UG UT WOS:000344113500009 ER PT S AU Choi, KK Jhabvala, MD Sun, J Jhabvala, CA Waczynski, A Olver, K AF Choi, K. K. Jhabvala, M. D. Sun, J. Jhabvala, C. A. Waczynski, A. Olver, K. BE Andresen, BF Fulop, GF Hanson, CM Norton, PR TI Resonator-QWIPs and FPAs SO INFRARED TECHNOLOGY AND APPLICATIONS XL SE Proceedings of SPIE LA English DT Proceedings Paper CT 40th Conference on Infrared Technology and Applications CY MAY 04-08, 2014 CL Baltimore, MD SP SPIE DE QWIP; resonance; FPA; electromagnetic; modeling; quantum efficiency ID WELL INFRARED PHOTODETECTOR AB The quantum efficiency of QWIPs is difficult to predict and optimize. Recently, we have established a quantitative 3-dimensional electromagnetic model for QE computation. In this work, we used this model to design and optimize new detector structures. In one approach, we adjusted the detector volume to resonate strongly with the scattered light from the diffractive elements (DEs). The resulting intensified field increases the detector QE correspondingly. We tested this resonator-QWIP concept on four detector materials and obtained satisfactory agreements between theory and experiment. The observed single detector QE ranges from 15 to 71%, depending on the realized pixel geometry and the matching detector material. We processed one of the materials into hybridized FPAs and observed a QE of 30% with a conversion efficiency of 11%, in agreement with theory. By using rings as DEs, the FPA spectral nonuniformity can also be minimized with an observed value of 4% in comparison with the 7% for gratings. With a proven EM model, we further designed different R-QWIPs for a wide range of applications, including high conversion efficiency detection, narrow band detection through a medium, narrow band detection at a gaseous medium, simultaneous two-color detection, sequential voltage tunable two-color detection, and broadband detection at Landsat wavelengths. Experimental efforts are underway. C1 [Choi, K. K.; Sun, J.; Olver, K.] US Army Res Lab, Electroopt & Photon Div, Adelphi, MD 20783 USA. [Jhabvala, M. D.; Jhabvala, C. A.; Waczynski, A.] NASA, Goddard Space Flight Ctr, Instrument Syst & Technol Div, Greenbelt, MD 20771 USA. RP Choi, KK (reprint author), US Army Res Lab, Electroopt & Photon Div, Adelphi, MD 20783 USA. EM kwong.k.choi.civ@mail.mil NR 11 TC 5 Z9 5 U1 0 U2 4 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-007-5 J9 PROC SPIE PY 2014 VL 9070 AR UNSP 907037 DI 10.1117/12.2049838 PG 12 WC Engineering, Electrical & Electronic; Optics; Physics, Applied SC Engineering; Optics; Physics GA BB5UG UT WOS:000344113500108 ER PT S AU Jackson, CR Ejzak, GA Aubailly, M Carhart, GW Liu, JJ Kiamilev, F AF Jackson, Christopher R. Ejzak, Garrett A. Aubailly, Mathieu Carhart, Gary W. Liu, J. Jiang Kiamilev, Fouad BE Andresen, BF Fulop, GF Hanson, CM Norton, PR TI Hardware acceleration of lucky-region fusion (LRF) algorithm for imaging SO INFRARED TECHNOLOGY AND APPLICATIONS XL SE Proceedings of SPIE LA English DT Proceedings Paper CT 40th Conference on Infrared Technology and Applications CY MAY 04-08, 2014 CL Baltimore, MD SP SPIE DE Lucky region fusion; imaging through turbulence; real-time image processing; FPGA; hardware simulation environment ID TURBULENCE; TELESCOPE; IMAGES AB "Lucky-region" fusion (LRF) is a synthetic imaging technique that has proven successful in enhancing the quality of images distorted by atmospheric turbulence. The LRF algorithm extracts sharp regions of an image obtained from a series of short exposure frames, and fuses the sharp regions into a final, improved image. In our previous research, the LRF algorithm had been implemented on a PC using the C programming language. However, the PC did not have sufficient processing power to handle real-time extraction, processing and reduction required when the LRF algorithm was applied to real-time video from fast, high-resolution image sensors rather than single picture images. This document describes a hardware implementation of the LRF algorithm on a VIRTEX-7 field programmable gate array (FPGA) to achieve real-time image processing. The novelty in our approach is the creation of a "black box" LRF video processing system with a general camera link input, a user controller interface, and a camera link or DVI video output. We also describe a custom hardware simulation environment we have built to test our LRF implementation. C1 [Jackson, Christopher R.; Ejzak, Garrett A.; Kiamilev, Fouad] Univ Delaware, Dept ECE, Newark, DE 19716 USA. [Aubailly, Mathieu] Univ Maryland, Intelligent Optic Lab, College Pk, MD 20742 USA. RDRL, CIE S, Army Res Lab, Adelphi, MD 20783 USA. RP Jackson, CR (reprint author), Univ Delaware, Dept ECE, Newark, DE 19716 USA. FU US ARMY RDECOM [W911NF- 11- 2- 0088] FX The authors thank past and present members of the CVORG research group at the University of Delaware, including David Koeplinger, William Maignan, Brian Gonzalez, Furkan Cayci, Nicholas Waite, and Kassem Nabha, for providing valuable technical advice and support. This project is collaboration with Dr. Jiang Liu, Dr. Mathieu Aubailly, and Mr. Gary Carhart of the Intelligent Optics Lab at the U. S. Army Research Laboratory ( ARL), Computational and Information Sciences Directorate ( CISD). The funding for this work is provided by a co- operative agreement award from the US ARMY RDECOM under contract number W911NF- 11- 2- 0088. NR 20 TC 0 Z9 0 U1 0 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-1-62841-007-5 J9 PROC SPIE PY 2014 VL 9070 AR UNSP 90703C DI 10.1117/12.2053898 PG 11 WC Engineering, Electrical & Electronic; Optics; Physics, Applied SC Engineering; Optics; Physics GA BB5UG UT WOS:000344113500113 ER EF