FN Thomson Reuters Web of Science™ VR 1.0 PT B AU Cox, MS AF Cox, Marcus S. BA Cox, MS BF Cox, MS TI SEGREGATED SOLDIERS MILITARY TRAINING AT HISTORICALLY BLACK COLLEGES IN THE JIM CROW SOUTH FOREWORD SO SEGREGATED SOLDIERS: MILITARY TRAINING AT HISTORICALLY BLACK COLLEGES IN THE JIM CROW SOUTH LA English DT Editorial Material; Book Chapter C1 US Army, Adelphi, MD USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LOUISIANA STATE UNIV PRESS PI BATON ROUGE PA BATON ROUGE, LA 70803 USA BN 978-0-8071-5177-8; 978-0-8071-5176-1 PY 2013 BP IX EP XII PG 4 WC History SC History GA BA0GE UT WOS:000331137900001 ER PT B AU Cox, MS AF Cox, Marcus S. BA Cox, MS BF Cox, MS TI MEN OF COLOR TO ARMS MILITARY TRAINING AND SERVICE AT BLACK COLLEGES IN THE LATE NINETEENTH CENTURY SO SEGREGATED SOLDIERS: MILITARY TRAINING AT HISTORICALLY BLACK COLLEGES IN THE JIM CROW SOUTH LA English DT Article; Book Chapter C1 US Army, Adelphi, MD USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LOUISIANA STATE UNIV PRESS PI BATON ROUGE PA BATON ROUGE, LA 70803 USA BN 978-0-8071-5177-8; 978-0-8071-5176-1 PY 2013 BP 10 EP + PG 24 WC History SC History GA BA0GE UT WOS:000331137900004 ER PT B AU Cox, MS AF Cox, Marcus S. BA Cox, MS BF Cox, MS TI SEGREGATED SOLDIERS MILITARY TRAINING AT HISTORICALLY BLACK COLLEGES IN THE JIM CROW SOUTH PREFACE SO SEGREGATED SOLDIERS: MILITARY TRAINING AT HISTORICALLY BLACK COLLEGES IN THE JIM CROW SOUTH LA English DT Editorial Material; Book Chapter C1 US Army, Adelphi, MD USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LOUISIANA STATE UNIV PRESS PI BATON ROUGE PA BATON ROUGE, LA 70803 USA BN 978-0-8071-5177-8; 978-0-8071-5176-1 PY 2013 BP XIII EP + PG 18 WC History SC History GA BA0GE UT WOS:000331137900002 ER PT B AU Cox, MS AF Cox, Marcus S. BA Cox, MS BF Cox, MS TI WE ARE ALL LOUISIANIANS AND BY THAT SIGN ALL AMERICANS NEGRO DEFENSE TRAINING, LEADERSHIP, AND WAR ACTIVITIES AT SOUTHERN UNIVERSITY DURING WORLD WAR II SO SEGREGATED SOLDIERS: MILITARY TRAINING AT HISTORICALLY BLACK COLLEGES IN THE JIM CROW SOUTH LA English DT Article; Book Chapter C1 US Army, Adelphi, MD USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LOUISIANA STATE UNIV PRESS PI BATON ROUGE PA BATON ROUGE, LA 70803 USA BN 978-0-8071-5177-8; 978-0-8071-5176-1 PY 2013 BP 30 EP + PG 28 WC History SC History GA BA0GE UT WOS:000331137900005 ER PT B AU Cox, MS AF Cox, Marcus S. BA Cox, MS BF Cox, MS TI SOLDIERING FOR UNCLE SAM MILITARY TRAINING AT SOUTHERN UNIVERSITY DURING THE COLD WAR, 1946-1960 SO SEGREGATED SOLDIERS: MILITARY TRAINING AT HISTORICALLY BLACK COLLEGES IN THE JIM CROW SOUTH LA English DT Article; Book Chapter C1 US Army, Adelphi, MD USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LOUISIANA STATE UNIV PRESS PI BATON ROUGE PA BATON ROUGE, LA 70803 USA BN 978-0-8071-5177-8; 978-0-8071-5176-1 PY 2013 BP 52 EP + PG 29 WC History SC History GA BA0GE UT WOS:000331137900006 ER PT B AU Cox, MS AF Cox, Marcus S. BA Cox, MS BF Cox, MS TI WHAT THE PEOPLE THINK AFRICAN AMERICAN ATTITUDES TOWARD MILITARY TRAINING AND SERVICE, 1950-1960 SO SEGREGATED SOLDIERS: MILITARY TRAINING AT HISTORICALLY BLACK COLLEGES IN THE JIM CROW SOUTH LA English DT Article; Book Chapter C1 US Army, Adelphi, MD USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LOUISIANA STATE UNIV PRESS PI BATON ROUGE PA BATON ROUGE, LA 70803 USA BN 978-0-8071-5177-8; 978-0-8071-5176-1 PY 2013 BP 74 EP + PG 39 WC History SC History GA BA0GE UT WOS:000331137900007 ER PT B AU Cox, MS AF Cox, Marcus S. BA Cox, MS BF Cox, MS TI OUR UNIFORM HASN'T LOST ITS PRESTIGE WITH OUR PEOPLE MILITARY TRAINING AND SERVICE ON THE BLUFF, 1960-1967 SO SEGREGATED SOLDIERS: MILITARY TRAINING AT HISTORICALLY BLACK COLLEGES IN THE JIM CROW SOUTH LA English DT Article; Book Chapter C1 US Army, Adelphi, MD USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LOUISIANA STATE UNIV PRESS PI BATON ROUGE PA BATON ROUGE, LA 70803 USA BN 978-0-8071-5177-8; 978-0-8071-5176-1 PY 2013 BP 101 EP + PG 43 WC History SC History GA BA0GE UT WOS:000331137900008 ER PT B AU Cox, MS AF Cox, Marcus S. BA Cox, MS BF Cox, MS TI KEEP OUR BLACK WARRIORS OUT OF THE DRAFT THE ANTIWAR MOVEMENT AT SOUTHERN UNIVERSITY, 1968-1973 SO SEGREGATED SOLDIERS: MILITARY TRAINING AT HISTORICALLY BLACK COLLEGES IN THE JIM CROW SOUTH LA English DT Article; Book Chapter C1 US Army, Adelphi, MD USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LOUISIANA STATE UNIV PRESS PI BATON ROUGE PA BATON ROUGE, LA 70803 USA BN 978-0-8071-5177-8; 978-0-8071-5176-1 PY 2013 BP 139 EP + PG 34 WC History SC History GA BA0GE UT WOS:000331137900009 ER PT B AU Cox, MS AF Cox, Marcus S. BA Cox, MS BF Cox, MS TI SEGREGATED SOLDIERS MILITARY TRAINING AT HISTORICALLY BLACK COLLEGES IN THE JIM CROW SOUTH CONCLUSION SO SEGREGATED SOLDIERS: MILITARY TRAINING AT HISTORICALLY BLACK COLLEGES IN THE JIM CROW SOUTH LA English DT Editorial Material; Book Chapter C1 US Army, Adelphi, MD USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LOUISIANA STATE UNIV PRESS PI BATON ROUGE PA BATON ROUGE, LA 70803 USA BN 978-0-8071-5177-8; 978-0-8071-5176-1 PY 2013 BP 168 EP + PG 13 WC History SC History GA BA0GE UT WOS:000331137900010 ER PT S AU Doty, TJ Hairston, WD Kellihan, B Canady, J Oie, KS McDowell, K AF Doty, Tracy J. Hairston, W. David Kellihan, Bret Canady, Jonroy Oie, Kelvin S. McDowell, Kaleb GP IEEE TI Developing a Wearable Real-World Neuroimaging System to Study Stress SO 2013 6TH INTERNATIONAL IEEE/EMBS CONFERENCE ON NEURAL ENGINEERING (NER) SE International IEEE EMBS Conference on Neural Engineering LA English DT Proceedings Paper CT 6th International IEEE EMBS Conference on Neural Engineering (NER) CY NOV 06-08, 2013 CL San Diego, CA SP IEEE EMBS, Battelle, Brain Vis LLC, Cortech Solut, Univ Minnesota, IGERT Program, Syst Neuroengineering, IOP Publishing, Ripple, Univ Minnesota, Inst Engn Med, Plexon ID DYNAMICS AB Neuroimaging technology has previously confined research to the laboratory setting, an environment that limits the generalizability of results to the real world. With the recent advent of high-density, wireless EEG technology, the promise of truly naturalistic neuroimaging research is closer than ever. This project presents a multi-aspect wearable neuroimaging system designed for use in daily life and tailored for studying stress. This system addresses several obstacles to collecting highly informative real-world neuroimaging data. First, neurophysiological data collected in a natural setting produces a rich dataset that is difficult to interpret without extensive contextual information. Our system provides this information from both user input and continuously collected physiological and actigraphy data. Second, the approach must minimally interfere with the user's life in order to avoid altering natural behavior. Our fully wearable, light-weight design integrates multiple components to maximize user comfort, while burden on the user is minimized by the use of a typical Android-based cell phone for occasional, brief interaction and also as the sole integration center for the system. While this system is optimized for the study of stress, the advances of this approach could be applied to study other naturally occurring psychological phenomena. C1 [Doty, Tracy J.; Hairston, W. David; Oie, Kelvin S.; McDowell, Kaleb] US Army Res Lab, Translat Neurosci Branch, Aberdeen Proving Ground, MD 21005 USA. [Kellihan, Bret; Canady, Jonroy] DCS Corp, Alexandria, VA 22310 USA. RP Doty, TJ (reprint author), US Army Res Lab, Translat Neurosci Branch, Aberdeen Proving Ground, MD 21005 USA. EM tracy.j.doty2.ctr@mail.mil; william.d.hairston4.civ@mail.mil OI Doty, Tracy/0000-0001-9921-2457 FU U.S. Army [W911NF-10-S-0002-0005]; U.S. Army Cooperative [W911NF-12-2-0019] FX Research supported by U.S. Army Contract: W911NF-10-S-0002-0005 and U.S. Army Cooperative Agreement: W911NF-12-2-0019. NR 16 TC 0 Z9 0 U1 0 U2 6 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1948-3546 BN 978-1-4673-1969-0 J9 I IEEE EMBS C NEUR E PY 2013 BP 786 EP 789 PG 4 WC Engineering, Biomedical; Neurosciences SC Engineering; Neurosciences & Neurology GA BA0HI UT WOS:000331259200194 ER PT S AU Clark, PE Clark, C AF Clark, Pamela Elizabeth Clark, Chuck BA Clark, PE Clark, C BF Clark, PE Clark, C TI Constant-Scale Natural Boundary Mapping in Context SO CONSTANT-SCALE NATURAL BOUNDARY MAPPING TO REVEAL GLOBAL AND COSMIC PROCESSES SE SpringerBriefs in Astronomy LA English DT Article; Book Chapter C1 [Clark, Pamela Elizabeth] Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. [Clark, Chuck] US Army Corps Engn, Jacksonville, FL USA. RP Clark, PE (reprint author), Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPRINGER PI NEW YORK PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES SN 2191-9100 BN 978-1-4614-7762-4; 978-1-4614-7761-7 J9 SPRINGERBRIEF ASTRON PY 2013 BP 1 EP + DI 10.1007/978-1-4614-7762-4_1 D2 10.1007/978-1-4614-7762-4 PG 31 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA BJV12 UT WOS:000330697600001 ER PT S AU Clark, PE Clark, C AF Clark, Pamela Elizabeth Clark, Chuck BA Clark, PE Clark, C BF Clark, PE Clark, C TI Constant-Scale Natural Boundary Mapping Technique SO CONSTANT-SCALE NATURAL BOUNDARY MAPPING TO REVEAL GLOBAL AND COSMIC PROCESSES SE SpringerBriefs in Astronomy LA English DT Article; Book Chapter C1 [Clark, Pamela Elizabeth] Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. [Clark, Chuck] US Army Corps Engn, Jacksonville, FL USA. RP Clark, PE (reprint author), Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPRINGER PI NEW YORK PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES SN 2191-9100 BN 978-1-4614-7762-4; 978-1-4614-7761-7 J9 SPRINGERBRIEF ASTRON PY 2013 BP 27 EP 42 DI 10.1007/978-1-4614-7762-4_2 D2 10.1007/978-1-4614-7762-4 PG 16 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA BJV12 UT WOS:000330697600002 ER PT S AU Clark, PE Clark, C AF Clark, Pamela Elizabeth Clark, Chuck BA Clark, PE Clark, C BF Clark, PE Clark, C TI Interpretation of CSNB Maps SO CONSTANT-SCALE NATURAL BOUNDARY MAPPING TO REVEAL GLOBAL AND COSMIC PROCESSES SE SpringerBriefs in Astronomy LA English DT Article; Book Chapter C1 [Clark, Pamela Elizabeth] Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. [Clark, Chuck] US Army Corps Engn, Jacksonville, FL USA. RP Clark, PE (reprint author), Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPRINGER PI NEW YORK PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES SN 2191-9100 BN 978-1-4614-7762-4; 978-1-4614-7761-7 J9 SPRINGERBRIEF ASTRON PY 2013 BP 43 EP 46 DI 10.1007/978-1-4614-7762-4_3 D2 10.1007/978-1-4614-7762-4 PG 4 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA BJV12 UT WOS:000330697600003 ER PT S AU Clark, PE Clark, C AF Clark, Pamela Elizabeth Clark, Chuck BA Clark, PE Clark, C BF Clark, PE Clark, C TI Mapping the Earth SO CONSTANT-SCALE NATURAL BOUNDARY MAPPING TO REVEAL GLOBAL AND COSMIC PROCESSES SE SpringerBriefs in Astronomy LA English DT Article; Book Chapter C1 [Clark, Pamela Elizabeth] Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. [Clark, Chuck] US Army Corps Engn, Jacksonville, FL USA. RP Clark, PE (reprint author), Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPRINGER PI NEW YORK PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES SN 2191-9100 BN 978-1-4614-7762-4; 978-1-4614-7761-7 J9 SPRINGERBRIEF ASTRON PY 2013 BP 47 EP 57 DI 10.1007/978-1-4614-7762-4_4 D2 10.1007/978-1-4614-7762-4 PG 11 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA BJV12 UT WOS:000330697600004 ER PT S AU Clark, PE Clark, C AF Clark, Pamela Elizabeth Clark, Chuck BA Clark, PE Clark, C BF Clark, PE Clark, C TI CSNB Mapping Applied to Regular Bodies SO CONSTANT-SCALE NATURAL BOUNDARY MAPPING TO REVEAL GLOBAL AND COSMIC PROCESSES SE SpringerBriefs in Astronomy LA English DT Article; Book Chapter C1 [Clark, Pamela Elizabeth] Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. [Clark, Chuck] US Army Corps Engn, Jacksonville, FL USA. RP Clark, PE (reprint author), Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPRINGER PI NEW YORK PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES SN 2191-9100 BN 978-1-4614-7762-4; 978-1-4614-7761-7 J9 SPRINGERBRIEF ASTRON PY 2013 BP 59 EP 69 DI 10.1007/978-1-4614-7762-4_5 D2 10.1007/978-1-4614-7762-4 PG 11 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA BJV12 UT WOS:000330697600005 ER PT S AU Clark, PE Clark, C AF Clark, Pamela Elizabeth Clark, Chuck BA Clark, PE Clark, C BF Clark, PE Clark, C TI CSNB Mapping Applied to Irregular Bodies SO CONSTANT-SCALE NATURAL BOUNDARY MAPPING TO REVEAL GLOBAL AND COSMIC PROCESSES SE SpringerBriefs in Astronomy LA English DT Article; Book Chapter C1 [Clark, Pamela Elizabeth] Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. [Clark, Chuck] US Army Corps Engn, Jacksonville, FL USA. RP Clark, PE (reprint author), Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPRINGER PI NEW YORK PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES SN 2191-9100 BN 978-1-4614-7762-4; 978-1-4614-7761-7 J9 SPRINGERBRIEF ASTRON PY 2013 BP 71 EP 88 DI 10.1007/978-1-4614-7762-4_6 D2 10.1007/978-1-4614-7762-4 PG 18 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA BJV12 UT WOS:000330697600006 ER PT S AU Clark, PE Clark, C AF Clark, Pamela Elizabeth Clark, Chuck BA Clark, PE Clark, C BF Clark, PE Clark, C TI Mapping the Sky SO CONSTANT-SCALE NATURAL BOUNDARY MAPPING TO REVEAL GLOBAL AND COSMIC PROCESSES SE SpringerBriefs in Astronomy LA English DT Article; Book Chapter C1 [Clark, Pamela Elizabeth] Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. [Clark, Chuck] US Army Corps Engn, Jacksonville, FL USA. RP Clark, PE (reprint author), Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPRINGER PI NEW YORK PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES SN 2191-9100 BN 978-1-4614-7762-4; 978-1-4614-7761-7 J9 SPRINGERBRIEF ASTRON PY 2013 BP 89 EP 94 DI 10.1007/978-1-4614-7762-4_7 D2 10.1007/978-1-4614-7762-4 PG 6 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA BJV12 UT WOS:000330697600007 ER PT S AU Clark, PE Clark, C AF Clark, Pamela Elizabeth Clark, Chuck BA Clark, PE Clark, C BF Clark, PE Clark, C TI The Future of CSNB Mapping SO CONSTANT-SCALE NATURAL BOUNDARY MAPPING TO REVEAL GLOBAL AND COSMIC PROCESSES SE SpringerBriefs in Astronomy LA English DT Article; Book Chapter C1 [Clark, Pamela Elizabeth] Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. [Clark, Chuck] US Army Corps Engn, Jacksonville, FL USA. RP Clark, PE (reprint author), Catholic Univ Amer, Inst Astrophys & Computat Sci, Washington, DC 20064 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPRINGER PI NEW YORK PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES SN 2191-9100 BN 978-1-4614-7762-4; 978-1-4614-7761-7 J9 SPRINGERBRIEF ASTRON PY 2013 BP 95 EP 99 DI 10.1007/978-1-4614-7762-4_8 D2 10.1007/978-1-4614-7762-4 PG 5 WC Astronomy & Astrophysics SC Astronomy & Astrophysics GA BJV12 UT WOS:000330697600008 ER PT S AU Hosmer, DW Lemeshow, S Sturdivant, RX AF Hosmer, David W., Jr. Lemeshow, Stanley Sturdivant, Rodney X. BA Hosmer, DW Lemeshow, S Sturdivant, RX BF Hosmer, DW Lemeshow, S Sturdivant, RX TI Introduction to the Logistic Regression Model SO APPLIED LOGISTIC REGRESSION, 3RD EDITION SE Wiley Series in Probability and Statistics LA English DT Editorial Material; Book Chapter C1 [Hosmer, David W., Jr.] Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. [Lemeshow, Stanley] Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USA. [Sturdivant, Rodney X.] US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. RP Hosmer, DW (reprint author), Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. NR 0 TC 4 Z9 4 U1 0 U2 6 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND SN 1940-6517 BN 978-0-470-58247-3 J9 WILEY SER PROBAB ST PY 2013 BP 1 EP 33 D2 10.1002/9781118548387 PG 33 WC Statistics & Probability SC Mathematics GA BJS50 UT WOS:000329984800002 ER PT S AU Hosmer, DW Lemeshow, S Sturdivant, RX AF Hosmer, David W., Jr. Lemeshow, Stanley Sturdivant, Rodney X. BA Hosmer, DW Lemeshow, S Sturdivant, RX BF Hosmer, DW Lemeshow, S Sturdivant, RX TI Applied Logistic Regression Third Edition Preface SO APPLIED LOGISTIC REGRESSION, 3RD EDITION SE Wiley Series in Probability and Statistics LA English DT Editorial Material; Book Chapter C1 [Hosmer, David W., Jr.] Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. [Lemeshow, Stanley] Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USA. [Sturdivant, Rodney X.] US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. RP Hosmer, DW (reprint author), Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. NR 0 TC 1 Z9 1 U1 1 U2 3 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND SN 1940-6517 BN 978-0-470-58247-3 J9 WILEY SER PROBAB ST PY 2013 BP XIII EP + D2 10.1002/9781118548387 PG 24 WC Statistics & Probability SC Mathematics GA BJS50 UT WOS:000329984800001 ER PT S AU Hosmer, DW Lemeshow, S Sturdivant, RX AF Hosmer, David W., Jr. Lemeshow, Stanley Sturdivant, Rodney X. BA Hosmer, DW Lemeshow, S Sturdivant, RX BF Hosmer, DW Lemeshow, S Sturdivant, RX TI The Multiple Logistic Regression Model SO APPLIED LOGISTIC REGRESSION, 3RD EDITION SE Wiley Series in Probability and Statistics LA English DT Article; Book Chapter C1 [Hosmer, David W., Jr.] Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. [Lemeshow, Stanley] Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USA. [Sturdivant, Rodney X.] US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. RP Hosmer, DW (reprint author), Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. NR 0 TC 5 Z9 5 U1 1 U2 1 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND SN 1940-6517 BN 978-0-470-58247-3 J9 WILEY SER PROBAB ST PY 2013 BP 35 EP 47 D2 10.1002/9781118548387 PG 13 WC Statistics & Probability SC Mathematics GA BJS50 UT WOS:000329984800003 ER PT S AU Hosmer, DW Lemeshow, S Sturdivant, RX AF Hosmer, David W., Jr. Lemeshow, Stanley Sturdivant, Rodney X. BA Hosmer, DW Lemeshow, S Sturdivant, RX BF Hosmer, DW Lemeshow, S Sturdivant, RX TI Interpretation of the Fitted Logistic Regression Model SO APPLIED LOGISTIC REGRESSION, 3RD EDITION SE Wiley Series in Probability and Statistics LA English DT Article; Book Chapter C1 [Hosmer, David W., Jr.] Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. [Lemeshow, Stanley] Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USA. [Sturdivant, Rodney X.] US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. RP Hosmer, DW (reprint author), Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. NR 0 TC 1 Z9 1 U1 0 U2 0 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND SN 1940-6517 BN 978-0-470-58247-3 J9 WILEY SER PROBAB ST PY 2013 BP 49 EP 88 D2 10.1002/9781118548387 PG 40 WC Statistics & Probability SC Mathematics GA BJS50 UT WOS:000329984800004 ER PT S AU Hosmer, DW Lemeshow, S Sturdivant, RX AF Hosmer, David W., Jr. Lemeshow, Stanley Sturdivant, Rodney X. BA Hosmer, DW Lemeshow, S Sturdivant, RX BF Hosmer, DW Lemeshow, S Sturdivant, RX TI Model-Building Strategies and Methods for Logistic Regression SO APPLIED LOGISTIC REGRESSION, 3RD EDITION SE Wiley Series in Probability and Statistics LA English DT Article; Book Chapter C1 [Hosmer, David W., Jr.] Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. [Lemeshow, Stanley] Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USA. [Sturdivant, Rodney X.] US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. RP Hosmer, DW (reprint author), Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. NR 0 TC 24 Z9 25 U1 2 U2 4 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND SN 1940-6517 BN 978-0-470-58247-3 J9 WILEY SER PROBAB ST PY 2013 BP 89 EP 151 D2 10.1002/9781118548387 PG 63 WC Statistics & Probability SC Mathematics GA BJS50 UT WOS:000329984800005 ER PT S AU Hosmer, DW Lemeshow, S Sturdivant, RX AF Hosmer, David W., Jr. Lemeshow, Stanley Sturdivant, Rodney X. BA Hosmer, DW Lemeshow, S Sturdivant, RX BF Hosmer, DW Lemeshow, S Sturdivant, RX TI Assessing the Fit of the Model SO APPLIED LOGISTIC REGRESSION, 3RD EDITION SE Wiley Series in Probability and Statistics LA English DT Article; Book Chapter C1 [Hosmer, David W., Jr.] Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. [Lemeshow, Stanley] Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USA. [Sturdivant, Rodney X.] US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. RP Hosmer, DW (reprint author), Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. NR 0 TC 9 Z9 9 U1 0 U2 1 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND SN 1940-6517 BN 978-0-470-58247-3 J9 WILEY SER PROBAB ST PY 2013 BP 153 EP 225 D2 10.1002/9781118548387 PG 73 WC Statistics & Probability SC Mathematics GA BJS50 UT WOS:000329984800006 ER PT S AU Hosmer, DW Lemeshow, S Sturdivant, RX AF Hosmer, David W., Jr. Lemeshow, Stanley Sturdivant, Rodney X. BA Hosmer, DW Lemeshow, S Sturdivant, RX BF Hosmer, DW Lemeshow, S Sturdivant, RX TI Application of Logistic Regression with Different Sampling Models SO APPLIED LOGISTIC REGRESSION, 3RD EDITION SE Wiley Series in Probability and Statistics LA English DT Article; Book Chapter C1 [Hosmer, David W., Jr.] Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. [Lemeshow, Stanley] Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USA. [Sturdivant, Rodney X.] US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. RP Hosmer, DW (reprint author), Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND SN 1940-6517 BN 978-0-470-58247-3 J9 WILEY SER PROBAB ST PY 2013 BP 227 EP 242 D2 10.1002/9781118548387 PG 16 WC Statistics & Probability SC Mathematics GA BJS50 UT WOS:000329984800007 ER PT S AU Hosmer, DW Lemeshow, S Sturdivant, RX AF Hosmer, David W., Jr. Lemeshow, Stanley Sturdivant, Rodney X. BA Hosmer, DW Lemeshow, S Sturdivant, RX BF Hosmer, DW Lemeshow, S Sturdivant, RX TI Logistic Regression for Matched Case-Control Studies SO APPLIED LOGISTIC REGRESSION, 3RD EDITION SE Wiley Series in Probability and Statistics LA English DT Article; Book Chapter C1 [Hosmer, David W., Jr.] Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. [Lemeshow, Stanley] Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USA. [Sturdivant, Rodney X.] US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. RP Hosmer, DW (reprint author), Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. NR 0 TC 2 Z9 2 U1 0 U2 1 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND SN 1940-6517 BN 978-0-470-58247-3 J9 WILEY SER PROBAB ST PY 2013 BP 243 EP 268 D2 10.1002/9781118548387 PG 26 WC Statistics & Probability SC Mathematics GA BJS50 UT WOS:000329984800008 ER PT S AU Hosmer, DW Lemeshow, S Sturdivant, RX AF Hosmer, David W., Jr. Lemeshow, Stanley Sturdivant, Rodney X. BA Hosmer, DW Lemeshow, S Sturdivant, RX BF Hosmer, DW Lemeshow, S Sturdivant, RX TI Logistic Regression Models for Multinomial and Ordinal Outcomes SO APPLIED LOGISTIC REGRESSION, 3RD EDITION SE Wiley Series in Probability and Statistics LA English DT Article; Book Chapter C1 [Hosmer, David W., Jr.] Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. [Lemeshow, Stanley] Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USA. [Sturdivant, Rodney X.] US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. RP Hosmer, DW (reprint author), Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. NR 0 TC 6 Z9 6 U1 0 U2 0 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND SN 1940-6517 BN 978-0-470-58247-3 J9 WILEY SER PROBAB ST PY 2013 BP 269 EP 311 D2 10.1002/9781118548387 PG 43 WC Statistics & Probability SC Mathematics GA BJS50 UT WOS:000329984800009 ER PT S AU Hosmer, DW Lemeshow, S Sturdivant, RX AF Hosmer, David W., Jr. Lemeshow, Stanley Sturdivant, Rodney X. BA Hosmer, DW Lemeshow, S Sturdivant, RX BF Hosmer, DW Lemeshow, S Sturdivant, RX TI Logistic Regression Models for the Analysis of Correlated Data SO APPLIED LOGISTIC REGRESSION, 3RD EDITION SE Wiley Series in Probability and Statistics LA English DT Article; Book Chapter C1 [Hosmer, David W., Jr.] Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. [Lemeshow, Stanley] Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USA. [Sturdivant, Rodney X.] US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. RP Hosmer, DW (reprint author), Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. NR 0 TC 0 Z9 0 U1 1 U2 2 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND SN 1940-6517 BN 978-0-470-58247-3 J9 WILEY SER PROBAB ST PY 2013 BP 313 EP 376 D2 10.1002/9781118548387 PG 64 WC Statistics & Probability SC Mathematics GA BJS50 UT WOS:000329984800010 ER PT S AU Hosmer, DW Lemeshow, S Sturdivant, RX AF Hosmer, David W., Jr. Lemeshow, Stanley Sturdivant, Rodney X. BA Hosmer, DW Lemeshow, S Sturdivant, RX BF Hosmer, DW Lemeshow, S Sturdivant, RX TI Special Topics SO APPLIED LOGISTIC REGRESSION, 3RD EDITION SE Wiley Series in Probability and Statistics LA English DT Article; Book Chapter C1 [Hosmer, David W., Jr.] Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. [Lemeshow, Stanley] Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USA. [Sturdivant, Rodney X.] US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. RP Hosmer, DW (reprint author), Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Dept Publ Hlth, Div Biostat & Epidemiol, Amherst, MA 01003 USA. NR 0 TC 1 Z9 1 U1 0 U2 1 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND SN 1940-6517 BN 978-0-470-58247-3 J9 WILEY SER PROBAB ST PY 2013 BP 377 EP 457 D2 10.1002/9781118548387 PG 81 WC Statistics & Probability SC Mathematics GA BJS50 UT WOS:000329984800011 ER PT J AU Myers, MA AF Myers, Mary Anne TI Keats and the Hands of Petrarch and Laura SO KEATS-SHELLEY JOURNAL LA English DT Article C1 US Mil Acad, West Point, NY 10996 USA. RP Myers, MA (reprint author), US Mil Acad, West Point, NY 10996 USA. NR 48 TC 0 Z9 0 U1 0 U2 1 PU KEATS-SHELLEY ASSOC AMER INC PI NEW YORK PA NEW YORK PUBLIC LIBRARY, RM 226, FIFTH AVE, 42ND ST, NEW YORK, NY 10018-2788 USA SN 0453-4387 J9 KEATS-SHELLEY J JI Keats-Shelley J. PY 2013 VL 62 BP 99 EP 113 PG 15 WC Poetry SC Literature GA AA9PO UT WOS:000331425600010 ER PT J AU Brockamp, T Maegele, M Gaarder, C Goslings, JC Cohen, MJ Lefering, R Joosse, P Naess, PA Skaga, NO Groat, T Eaglestone, S Borgman, MA Spinella, PC Schreiber, MA Brohi, K AF Brockamp, Thomas Maegele, Marc Gaarder, Christine Goslings, J. Carel Cohen, Mitchell J. Lefering, Rolf Joosse, Pieter Naess, Paal A. Skaga, Nils O. Groat, Tahnee Eaglestone, Simon Borgman, Matthew A. Spinella, Philip C. Schreiber, Martin A. Brohi, Karim TI Comparison of the predictive performance of the BIG, TRISS, and PS09 score in an adult trauma population derived from multiple international trauma registries SO CRITICAL CARE LA English DT Article ID GLASGOW COMA SCALE; BASE DEFICIT; OUTCOME PREDICTION; COAGULOPATHY; MORTALITY; INJURY; HYPOPERFUSION; TRANSFUSION; MECHANISM; MODEL AB Background: The BIG score (Admission base deficit (B), International normalized ratio (I), and Glasgow Coma Scale (G)) has been shown to predict mortality on admission in pediatric trauma patients. The objective of this study was to assess its performance in predicting mortality in an adult trauma population, and to compare it with the existing Trauma and Injury Severity Score (TRISS) and probability of survival (PS09) score. Materials and methods: A retrospective analysis using data collected between 2005 and 2010 from seven trauma centers and registries in Europe and the United States of America was performed. We compared the BIG score with TRISS and PS09 scores in a population of blunt and penetrating trauma patients. We then assessed the discrimination ability of all scores via receiver operating characteristic (ROC) curves and compared the expected mortality rate (precision) of all scores with the observed mortality rate. Results: In total, 12,206 datasets were retrieved to validate the BIG score. The mean ISS was 15 +/- 11, and the mean 30-day mortality rate was 4.8%. With an AUROC of 0.892 (95% confidence interval (CI): 0.879 to 0.906), the BIG score performed well in an adult population. TRISS had an area under ROC (AUROC) of 0.922 (0.913 to 0.932) and the PS09 score of 0.825 (0.915 to 0.934). On a penetrating-trauma population, the BIG score had an AUROC result of 0.920 (0.898 to 0.942) compared with the PS09 score (AUROC of 0.921; 0.902 to 0.939) and TRISS (0.929; 0.912 to 0.947). Conclusions: The BIG score is a good predictor of mortality in the adult trauma population. It performed well compared with TRISS and the PS09 score, although it has significantly less discriminative ability. In a penetrating-trauma population, the BIG score performed better than in a population with blunt trauma. The BIG score has the advantage of being available shortly after admission and may be used to predict clinical prognosis or as a research tool to risk stratify trauma patients into clinical trials. C1 [Brockamp, Thomas; Maegele, Marc; Lefering, Rolf] Univ Witten Herdecke, CMMC, Dept Traumatol & Orthoped Surg, D-51109 Cologne, Germany. [Gaarder, Christine; Naess, Paal A.] Oslo Univ Hosp Ulleval, Div Crit Care, Dept Traumatol, N-0407 Oslo, Norway. [Skaga, Nils O.] Oslo Univ Hosp Ulleval, Div Emergency & Crit Care, Dept Anesthesiol, N-0407 Oslo, Norway. [Goslings, J. Carel; Joosse, Pieter] Univ Amsterdam, Acad Med Ctr, Dept Surg, Trauma Unit, NL-1105 AZ Amsterdam, Netherlands. [Groat, Tahnee] Univ Calif San Francisco CA, San Francisco Gen Hosp, Dept Surg, San Francisco, CA 94143 USA. [Schreiber, Martin A.] Oregon Hlth & Sci Univ, Dept Surg, Div Trauma Crit Care & Acute Care Surg, Portland, OR 97239 USA. [Borgman, Matthew A.] San Antonio Mil Med Ctr, Dept Pediat, San Antonio, TX 78234 USA. [Spinella, Philip C.] Washington Univ St Louis, St Louis Childrens Hosp, Div Pediat Crit Care, Translat Res Program, St Louis, MO 63110 USA. [Spinella, Philip C.] US Army, Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Eaglestone, Simon; Brohi, Karim] Queen Mary Univ London, Barts & London Sch Med & Dent, London E1 2AT, England. RP Brockamp, T (reprint author), Univ Witten Herdecke, CMMC, Dept Traumatol & Orthoped Surg, Ostmerheimer Str 200, D-51109 Cologne, Germany. EM tbrockamp@gmail.com RI Borgman, Matthew/L-9477-2015 OI Borgman, Matthew/0000-0002-2008-7380 NR 32 TC 7 Z9 7 U1 0 U2 2 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1466-609X EI 1364-8535 J9 CRIT CARE JI Crit. Care PY 2013 VL 17 IS 4 AR R134 DI 10.1186/cc12813 PG 9 WC Critical Care Medicine SC General & Internal Medicine GA AB1GO UT WOS:000331539700008 PM 23844754 ER PT J AU Vecchi, V Langer, T Bellomi, M Rampinelli, C Chung, KK Cancio, LC Gattinoni, L Batchinsky, AI AF Vecchi, Vittoria Langer, Thomas Bellomi, Massimo Rampinelli, Cristiano Chung, Kevin K. Cancio, Leopoldo C. Gattinoni, Luciano Batchinsky, Andriy I. TI Low-dose CT for quantitative analysis in acute respiratory distress syndrome SO CRITICAL CARE LA English DT Article ID END-EXPIRATORY PRESSURE; COMPUTED-TOMOGRAPHY; RADIATION-EXPOSURE; CHEST CT; ALVEOLAR RECRUITMENT; LUNG AERATION; IMAGE QUALITY; VENTILATION; PULMONARY; QUANTIFICATION AB Introduction: The clinical use of serial quantitative computed tomography (CT) to characterize lung disease and guide the optimization of mechanical ventilation in patients with acute respiratory distress syndrome (ARDS) is limited by the risk of cumulative radiation exposure and by the difficulties and risks related to transferring patients to the CT room. We evaluated the effects of tube current-time product (mAs) variations on quantitative results in healthy lungs and in experimental ARDS in order to support the use of low-dose CT for quantitative analysis. Methods: In 14 sheep chest CT was performed at baseline and after the induction of ARDS via intravenous oleic acid injection. For each CT session, two consecutive scans were obtained applying two different mAs: 60 mAs was paired with 140, 15 or 7.5 mAs. All other CT parameters were kept unaltered (tube voltage 120 kVp, collimation 32 x 0.5 mm, pitch 0.85, matrix 512 x 512, pixel size 0.625 x 0.625 mm). Quantitative results obtained at different mAs were compared via Bland-Altman analysis. Results: Good agreement was observed between 60 mAs and 140 mAs and between 60 mAs and 15 mAs (all biases less than 1%). A further reduction of mAs to 7.5 mAs caused an increase in the bias of poorly aerated and nonaerated tissue (-2.9% and 2.4%, respectively) and determined a significant widening of the limits of agreement for the same compartments (-10.5% to 4.8% for poorly aerated tissue and -5.9% to 10.8% for nonaerated tissue). Estimated mean effective dose at 140, 60, 15 and 7.5 mAs corresponded to 17.8, 7.4, 2.0 and 0.9 mSv, respectively. Image noise of scans performed at 140, 60, 15 and 7.5 mAs corresponded to 10, 16, 38 and 74 Hounsfield units, respectively. Conclusions: A reduction of effective dose up to 70% has been achieved with minimal effects on lung quantitative results. Low-dose computed tomography provides accurate quantitative results and could be used to characterize lung compartment distribution and possibly monitor time-course of ARDS with a lower risk of exposure to ionizing radiation. A further radiation dose reduction is associated with lower accuracy in quantitative results. C1 [Vecchi, Vittoria; Langer, Thomas; Chung, Kevin K.; Cancio, Leopoldo C.; Batchinsky, Andriy I.] US Army, Inst Surg Res, Comprehens Intens Care Res Task Area, Ft Sam Houston, TX 78234 USA. [Vecchi, Vittoria; Bellomi, Massimo] Univ Milan, Sch Med, I-20122 Milan, Italy. [Vecchi, Vittoria; Langer, Thomas] Natl Acad, Natl Res Council, Washington, DC 20001 USA. [Langer, Thomas; Gattinoni, Luciano] Univ Milan, Dipartimento Fisiopatol Medicochirurg & Trapianti, I-20122 Milan, Italy. [Bellomi, Massimo; Rampinelli, Cristiano] Ist Europeo Oncol, Dipartimento Radiol, I-20141 Milan, Italy. [Gattinoni, Luciano] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Dipartimento Anestesia Rianimaz Intens & Subinten, I-20122 Milan, Italy. RP Langer, T (reprint author), US Army, Inst Surg Res, Comprehens Intens Care Res Task Area, 3698 Chambers Pass, Ft Sam Houston, TX 78234 USA. EM thomas.langer@unimi.it FU US Army Institute of Surgical Research FX The authors are indebted to Peter Herrmann and Michael Quintel of the Department of Anesthesiology, University of Gottingen, Germany, who kindly provided Maluna, the software used for quantitative analysis; to Alisa Leon for valuable technical assistance with CT image acquisition; and to Lawrence R Goodman of the Division of Diagnostic Radiology, Department of Radiology, and Department of Pulmonary Medicine & Critical Care, Medical College of Wisconsin, for his useful suggestions. Funding was received from the US Army Institute of Surgical Research. The opinions and assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the US Department of the Army or the US Department of Defense. NR 39 TC 9 Z9 11 U1 0 U2 1 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1466-609X EI 1364-8535 J9 CRIT CARE JI Crit. Care PY 2013 VL 17 IS 4 AR R183 DI 10.1186/cc12866 PG 10 WC Critical Care Medicine SC General & Internal Medicine GA AB1GO UT WOS:000331539700056 PM 24004842 ER PT J AU Wade, CE Baer, LA Wu, XW Silliman, DT Walters, TJ Wolf, SE AF Wade, Charles E. Baer, Lisa A. Wu, Xiaowu Silliman, David T. Walters, Thomas J. Wolf, Steven E. TI Severe burn and disuse in the rat independently adversely impact body composition and adipokines SO CRITICAL CARE LA English DT Article ID SKELETAL-MUSCLE; THERMAL-INJURY; PROTEIN-TURNOVER; CRITICAL ILLNESS; HYPERMETABOLIC RESPONSE; LEPTIN CONCENTRATIONS; FLUID RESUSCITATION; SERUM ADIPONECTIN; EARLY EXCISION; FOOD-INTAKE AB Introduction: Severe trauma is accompanied by a period of hypermetabolism and disuse. In this study, a rat model was used to determine the effects of burn and disuse independently and in combination on body composition, food intake and adipokines. Methods: Male rats were assigned to four groups 1) sham ambulatory (SA), 2) sham hindlimb unloaded (SH), 3) 40% total body surface area full thickness scald burn ambulatory (BA) and 4) burn and hindlimb unloaded (BH). Animals designated to the SH and BH groups were placed in a tail traction system and their hindlimbs unloaded. Animals were followed for 14 days. Plasma, urine, fecal and tissue samples were analyzed. Results: SA had a progressive increase in body mass (BM), SH and BA no change and BH a reduction. Compared to SA, BM was reduced by 10% in both SH and BA and by 17% when combined in BH. Compared to SA, all groups had reductions in lean and fat body mass with BH being greater. The decrease in lean mass was associated with the rate of urinary corticosterone excretion. The loss in fat mass was associated with decreases in plasma leptin and adiponectin and an increase in ghrelin. Following the acute response to injury, BH had a greater food intake per 100 g BM. Food intake was associated with the levels of leptin, adiponectin and ghrelin. Conclusions: The effects of the combination of burn and disuse in this animal model were additive, therefore in assessing metabolic changes with severe trauma both injury and disuse should be considered. Furthermore, the observed changes in adipokines, corticosterone and ghrelin provide insights for interventions to attenuate the hypermetabolic state following injury, possibly reducing catabolism and muscle loss and subsequent adverse effects on recovery and function. C1 [Wade, Charles E.; Baer, Lisa A.; Wu, Xiaowu; Silliman, David T.; Walters, Thomas J.; Wolf, Steven E.] US Army, Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Wade, Charles E.; Wu, Xiaowu; Wolf, Steven E.] Univ Texas Hlth Sci Ctr San Antonio, Dept Surg, San Antonio, TX 78229 USA. [Wade, Charles E.; Baer, Lisa A.] Univ Texas Hlth Sci Ctr Houston, Dept Surg, Houston, TX 77030 USA. [Wade, Charles E.; Baer, Lisa A.] Univ Texas Hlth Sci Ctr Houston, Ctr Translat Injury Res, Houston, TX 77030 USA. RP Wade, CE (reprint author), US Army, Inst Surg Res, Ft Sam Houston, TX 78234 USA. EM charles.e.wade@uth.tmc.edu OI Wolf, Steven/0000-0003-2972-3440 FU National Institutes of Health [1 R01 GM063120-04]; Technologies for Metabolic Monitoring (TMM)/Julia Weaver Fund; Congressionally Directed Program FX The authors would like to thank Angela Beeler for her editorial assistance. Funding for this project was provided by the National Institutes of Health (1 R01 GM063120-04); The Technologies for Metabolic Monitoring (TMM)/Julia Weaver Fund, A Congressionally Directed Program Jointly Managed by the USA MRMC, NIH, NASA and the Juvenile Diabetes Research Foundation; Combat Casualty Care Division, United States Army Medical Research and Materiel Command. The funding sources played no role in the design of the study, collection, analysis, and interpretation of data, in writing the manuscript or the decision to submit for publication. NR 65 TC 7 Z9 7 U1 0 U2 0 PU BIOMED CENTRAL LTD PI LONDON PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND SN 1466-609X EI 1364-8535 J9 CRIT CARE JI Crit. Care PY 2013 VL 17 IS 5 AR R225 DI 10.1186/cc13048 PG 12 WC Critical Care Medicine SC General & Internal Medicine GA AB1HA UT WOS:000331540900041 PM 24099533 ER PT J AU Cali, J Geng, XY Zhao, F Pukish, M Dai, F Aklian, A AF Cali, Joseph Geng, Xueyeng Zhao, Feng Pukish, Michael Dai, Foster Aklian, Andre GP IEEE TI A 650 MHz DDFS for Stretch Processing Radar in 130nm BiCMOS Process SO 2013 8TH EUROPEAN MICROWAVE INTEGRATED CIRCUITS CONFERENCE (EUMIC) SE European Microwave Integrated Circuits Conference - Proceedings LA English DT Proceedings Paper CT 8th European Microwave Integrated Circuits Conference (EuMIC) CY OCT 06-08, 2013 CL Nuremberg, GERMANY SP Electron Devices Soc, GAAS DE DDFS; Direct Digital Frequency Synthesis; DDS; Direct Digital Synthesis; DCDO; Chirp; Linear Phase Modulation; LPM; Linear Frequency Modulation; LFM ID DIRECT DIGITAL SYNTHESIZER; TECHNOLOGY; DAC AB A quadrature 650 MHz direct digital frequency synthesizer (DDFS) with linear phase and frequency modulation capabilities is realized in a 130nm BiCMOS process. The DDFS supports stretch processing pulse compression for a single chip radar transceiver (RoC). The design features a partial dynamic rotation (PDR) Cordinate Rotation DIgital Computer (CORDIC) for the phase to sine and cosine mapping functions (SCMF), a 32 bit phase accumulator with a 0.23 Hz frequency resolution at native operating frequency, 32 bit linear frequency modulation (LFM), 14-bit linear phase modulation (LPM), additive dithering for randomization of phase truncation spurs, two inverse sinc functions for zero-order hold (ZOH) transfer function correction of the DAC, stretch processing radar control circuitry and two twelve bit CMOS current steering DACs. C1 [Cali, Joseph; Geng, Xueyeng; Zhao, Feng; Pukish, Michael; Dai, Foster] Auburn Univ, Auburn, AL 36849 USA. [Aklian, Andre] US Army Res, RDECOM CERDEC Intelligence & Informat Warfare Dir, Adelphi, MD USA. RP Cali, J (reprint author), Auburn Univ, Auburn, AL 36849 USA. FU U.S. Army [W15P7T-09-C-S320]; Jonathan Corriveau and Geoffrey Goldman FX This work is supported by the U.S. Army under Contract No. W15P7T-09-C-S320. The authors would like to acknowledge Jonathan Corriveau and Geoffrey Goldman for funding and managing this project. NR 6 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-2-87487-032-3 J9 EUR MICROW INTEGRAT PY 2013 BP 33 EP 36 PG 4 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA BA0AB UT WOS:000330766400009 ER PT S AU Murphey, YL Park, J Masrur, MA AF Murphey, Yi Lu Park, Jungme Masrur, M. Abul GP IEEE TI Intelligent Energy Management in a Low Cost Hybrid Electric Vehicle Power System SO 2013 IEEE 78TH VEHICULAR TECHNOLOGY CONFERENCE (VTC FALL) SE IEEE Vehicular Technology Conference Proceedings LA English DT Proceedings Paper CT IEEE 78th Vehicular Technology Conference (VTC Fall) CY SEP 02-05, 2013 CL Las Vegas, NV SP IEEE DE Dynamic Programming; vehicle energy management; all terrain vehicle AB This paper presents our research in vehicle energy optimization for a low-cost HEV power system that only allows the control of engine on/off and driving at three different speed limits. We present algorithms for modeling vehicle energy flow and optimization and machine learning of optimal control settings generated by Dynamic Programming on real-world drive cycles, and an intelligent energy controller designed for online energy control. Experimental results show the intelligent controller has the capability of 11% fuel saving. C1 [Murphey, Yi Lu; Park, Jungme] Univ Michigan, Dept Elect & Comp Engn, Dearborn, MI 48128 USA. [Masrur, M. Abul] US Army, RD ECOM TARDEC, Warren, MI 48397 USA. RP Murphey, YL (reprint author), Univ Michigan, Dept Elect & Comp Engn, Dearborn, MI 48128 USA. EM yilu@umich.edu FU US Army RDECOM-TARDEC FX This research was supported in part by a research grant from the US Army RDECOM-TARDEC. NR 6 TC 0 Z9 0 U1 1 U2 4 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1550-2252 BN 978-1-4673-6187-3 J9 IEEE VTS VEH TECHNOL PY 2013 PG 5 WC Engineering, Electrical & Electronic; Telecommunications; Transportation Science & Technology SC Engineering; Telecommunications; Transportation GA BJU51 UT WOS:000330585400223 ER PT S AU Hill, KK Smith, TJ AF Hill, Karen K. Smith, Theresa J. BE Rummel, A Binz, T TI Genetic Diversity Within Clostridium botulinum Serotypes, Botulinum Neurotoxin Gene Clusters and Toxin Subtypes SO BOTULINUM NEUROTOXINS SE Current Topics in Microbiology and Immunology LA English DT Review; Book Chapter DE Subtype; OrfX toxin gene cluster; Ha toxin gene cluster; Horizontal gene transfer; Phylogentic tree; Clostridium botulinum genome ID FRAGMENT LENGTH POLYMORPHISM; FIELD GEL-ELECTROPHORESIS; E STRAINS; GENOME SEQUENCE; COMPLEX GENES; PLASMID; INTERRELATIONSHIPS; IDENTIFICATION; BUTYRICUM; BACILLUS AB Clostridium botulinum is a species of spore-forming anaerobic bacteria defined by the expression of any one or two of seven serologically distinct botulinum neurotoxins (BoNTs) designated BoNT/A-G. This Gram-positive bacterium was first identified in 1897 and since then the paralyzing and lethal effects of its toxin have resulted in the recognition of different forms of the intoxication known as food-borne, infant, or wound botulism. Early microbiological and biochemical characterization of C. botulinum isolates revealed that the bacteria within the species had different characteristics and expressed different toxin types. To organize the variable bacterial traits within the species, Group I-IV designations were created. Interestingly, it was observed that isolates within different Groups could express the same toxin type and conversely a single Group could express different toxin types. This discordant phylogeny between the toxin and the host bacteria indicated that horizontal gene transfer of the toxin was responsible for the variation observed within the species. The recent availability of multiple C. botulinum genomic sequences has offered the ability to bioinformatically analyze the locations of the bont genes, the composition of their toxin gene clusters, and the genes flanking these regions to understand their variation. Comparison of the genomic sequences representing multiple serotypes indicates that the bont genes are not in random locations. Instead the analyses revealed specific regions where the toxin genes occur within the genomes representing serotype A, B, C, E, and F C. botulinum strains and C. butyricum type E strains. The genomic analyses have provided evidence of horizontal gene transfer, site-specific insertion, and recombination events. These events have contributed to the variation observed among the neurotoxins, the toxin gene clusters and the bacteria that contain them, and has supported the historical microbiological, and biochemical characterization of the Group classification within the species. C1 [Hill, Karen K.] Los Alamos Natl Lab, Los Alamos, NM 87545 USA. [Smith, Theresa J.] US Army, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA. RP Hill, KK (reprint author), Los Alamos Natl Lab, Mail Stop M 888, Los Alamos, NM 87545 USA. EM khill@lanl.gov; theresa.smith@amedd.army.mil NR 53 TC 79 Z9 79 U1 1 U2 27 PU SPRINGER-VERLAG BERLIN PI BERLIN PA HEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY SN 0070-217X BN 978-3-642-33570-9; 978-3-642-33569-3 J9 CURR TOP MICROBIOL JI Curr.Top.Microbiol.Immunol. PY 2013 VL 364 BP 1 EP 20 DI 10.1007/978-3-642-33570-9_1 D2 10.1007/978-3-642-33570-9 PG 20 WC Immunology; Microbiology SC Immunology; Microbiology GA BJT57 UT WOS:000330226500002 PM 23239346 ER PT J AU Wolfe, JM Brunelli, DN Rubinstein, J Horowitz, TS AF Wolfe, Jeremy M. Brunelli, David N. Rubinstein, Joshua Horowitz, Todd S. TI Prevalence effects in newly trained airport checkpoint screeners: Trained observers miss rare targets, too SO JOURNAL OF VISION LA English DT Article DE visual search; prevalence effects; airport security; visual attention; error rates; criterion shift ID VISUAL-SEARCH; SENSITIVITY DECREMENT; SIGNAL PROBABILITY; CORRECTABLE SEARCH; VIGILANCE; SATISFACTION; PERFORMANCE; CRITERION; TASKS; TIME AB Many socially important search tasks are characterized by low target prevalence, meaning that targets are rarely encountered. For example, transportation security officers (TSOs) at airport checkpoints encounter very few actual threats in carry-on bags. In laboratory-based visual search experiments, low prevalence reduces the probability of detecting targets (Wolfe, Horowitz, & Kenner, 2005). In the lab, this "prevalence effect" is caused by changes in decision and response criteria (Wolfe & Van Wert, 2010) and can be mitigated by presenting a burst of high-prevalence search with feedback (Wolfe et al., 2007). The goal of this study was to see if these effects could be replicated in the field with TSOs. A total of 125 newly trained TSOs participated in one of two experiments as part of their final evaluation following training. They searched for threats in simulated bags across five blocks. The first three blocks were low prevalence (target prevalence <= .05) with no feedback; the fourth block was high prevalence (.50) with full feedback; and the final block was, again, low prevalence. We found that newly trained TSOs were better at detecting targets at high compared to low prevalence, replicating the prevalence effect. Furthermore, performance was better (and response criterion was more "liberal") in the low-prevalence block that took place after the high-prevalence block than in the initial three low-prevalence blocks, suggesting that a burst of high-prevalence trials may help alleviate the prevalence effect in the field. C1 [Wolfe, Jeremy M.; Horowitz, Todd S.] Brigham & Womens Hosp, Visual Attent Lab, Cambridge, MA 02138 USA. [Wolfe, Jeremy M.; Horowitz, Todd S.] Harvard Univ, Sch Med, Boston, MA USA. [Brunelli, David N.] Transportat Secur Adm, Chelsea Reg Training Ctr, Chelsea, MA USA. [Rubinstein, Joshua] ARDEC Field Element, HRED, Army Res Lab, Picatinny Arsenal, NJ USA. RP Wolfe, JM (reprint author), Brigham & Womens Hosp, Visual Attent Lab, Cambridge, MA 02138 USA. EM wolfe@search.bwh.harvard.edu RI Wolfe, Jeremy/C-1621-2012; Wolfe, Jeremy/A-9248-2016 OI Wolfe, Jeremy/0000-0002-6475-1984; Wolfe, Jeremy/0000-0002-6475-1984 FU U.S. Department of Homeland Security Science and Technology Directorate; Transportation Security Administration; NIH [EY017001] FX JMW and TSH were supported by funding from the U.S. Department of Homeland Security Science and Technology Directorate and the Transportation Security Administration and by NIH grant EY017001. NR 45 TC 13 Z9 13 U1 2 U2 11 PU ASSOC RESEARCH VISION OPHTHALMOLOGY INC PI ROCKVILLE PA 12300 TWINBROOK PARKWAY, ROCKVILLE, MD 20852-1606 USA SN 1534-7362 J9 J VISION JI J. Vision PY 2013 VL 13 IS 3 SI SI AR 33 DI 10.1167/13.3.33 PG 9 WC Ophthalmology SC Ophthalmology GA AA2BH UT WOS:000330899600021 PM 24297778 ER PT J AU Howard, HR Wang, G Singer, S Anderson, AB AF Howard, H. R. Wang, G. Singer, S. Anderson, A. B. TI MODELING AND PREDICTION OF LAND CONDITION FOR FORT RILEY MILITARY INSTALLATION SO TRANSACTIONS OF THE ASABE LA English DT Article DE Land condition prediction; Linear and nonlinear models; Military training impact; Stepwise regression; TM images ID LONG-TERM DISTURBANCE; MIXED PRAIRIE; UNCERTAINTY; MANAGEMENT; VEGETATION; VARIABLES; TEXAS; HOOD AB In the U. S., the Department of Defense manages more than 5500 military installations that occupy approximately 12 million ha of land. These lands are used for various military training programs. Training activities inevitably degrade the land condition, and the degraded land condition, in turn, limits the land's military training carrying capacity. To sustain the military training land carrying capacity and the environment, land managers must monitor and predict changes to the land condition under various military training schemes. The objective of this study is to develop prediction models for land condition based on military training intensity and on independent variables that play a significant role in driving land condition changes at Fort Riley, Kansas. It is assumed that land condition can be quantified using soil erosion as a surrogate measure, which is mainly determined by a ground and vegetation cover factor, in which the larger the factor, the poorer the land condition. In addition to military training intensity, the independent variables used in these prediction models of land condition included distance from the location to roads, terrain slope (which affects military training access), ground cover, landscape fragmentation (an indirect measure of military training induced disturbance), and spatial variability of canopy cover and military training induced disturbance (as reflected in Landsat Thematic Mapper [TM] images). Various regression models were developed, and predictions made by linear and nonlinear models were compared with and without TM images, with and without stepwise regression procedures, and with and without historical land condition variables. Results showed that the absolute Pearson product moment correlation coefficients of ground cover with the cover factor were larger than 0.63; the correlation was greatest and significant at a risk level of 5%. Ground cover was thus involved in all the stepwise regression and nonlinear models. Although military training intensity was significantly correlated with the cover factor, training intensity was excluded from the best models mainly because both ground cover and landscape fragmentation that existed in the models also reflected the military training induced disturbance. Compared to models in which all the variables were involved, the stepwise regression models reduced the number of the independent variables from 11 or 15 to 3 or 6 (depending on analysis year) with no significant loss of accuracy. In most cases, adding the near and middle infrared TM images, which revealed the spatial variability of military training induced disturbance, improved the prediction of land condition. Based on the correlation coefficient and root mean square error (RMSE) between the predicted and observed values of the cover factor, the nonlinear models that used significant independent variables led to more accurate predictions than the linear regression models. This suggests that the combination of stepwise regression and nonlinear models could increase the accuracy of prediction. Moreover, adding the historical land condition variables, such as historical cover factor and ground cover, into the models could greatly decrease prediction errors. C1 [Howard, H. R.] US Army Engn Res & Dev Ctr, Construct Engn Res Lab ERDC CERL, Champaign, IL USA. [Wang, G.] So Illinois Univ, Dept Geog & Environm Resources, Carbondale, IL 62901 USA. [Singer, S.; Anderson, A. B.] ERDC CERL, Champaign, IL USA. RP Wang, G (reprint author), So Illinois Univ, 4442 Faner Hall, Carbondale, IL 62901 USA. EM gxwang@siu.edu FU U.S. Engineer Research and Development Center, Construction Engineering Research Laboratory (ERDC-CERL) [EQI A896] FX We are grateful to U.S. Engineer Research and Development Center, Construction Engineering Research Laboratory (ERDC-CERL) for providing support (under the EQI A896 program) and data sets for this study. NR 29 TC 4 Z9 4 U1 0 U2 2 PU AMER SOC AGRICULTURAL & BIOLOGICAL ENGINEERS PI ST JOSEPH PA 2950 NILES RD, ST JOSEPH, MI 49085-9659 USA SN 2151-0032 EI 2151-0040 J9 T ASABE JI Trans. ASABE PY 2013 VL 56 IS 2 BP 643 EP 652 PG 10 WC Agricultural Engineering SC Agriculture GA AA0EH UT WOS:000330767600024 ER PT J AU Mitchell, KN Wang, BX Khodakarami, M AF Mitchell, Kenneth Ned Wang, Bruce X. Khodakarami, Mohammadadel TI Selection of Dredging Projects for Maximizing Waterway System Performance SO TRANSPORTATION RESEARCH RECORD LA English DT Article ID CAPITAL ALLOCATION; ISLAND MODELS; OPTIMIZATION; SIMULATION AB Budget allocation to annual maintenance dredging projects conducted by the U.S. Army Corps of Engineers is addressed. Of the many projects requested, only a subset may be selected for funding because of budgetary constraints. The benefits of conducting maintenance dredging at one dredging project depend on other projects in the system that also are being dredged to take advantage of transportation efficiency gains derived from deeper navigable waterways. The proposed integer programming models and heuristic solution algorithms selected dredging projects for funding, while taking into account interdependent benefits. The models considered the waterway network topology, which was derived from flow data of historic waterborne cargo. The solution algorithms ensured efficient computational performance and quality of solutions. The models and algorithms were tested on example port systems from the Great Lakes region, as well as from mainline coastal ports and inland waterways. The models were shown to increase the amounts of system cargo throughput directly supported by dredging relative to traditional rank-order approaches that did not consider project interdependencies. This result was true especially for scenarios in which the overall budget was small relative to the total of all funding requests in question. C1 [Mitchell, Kenneth Ned] US Army Engineer Res & Dev Ctr, Coastal & Hydraul Lab, Vicksburg, MS 39180 USA. [Wang, Bruce X.; Khodakarami, Mohammadadel] Texas A&M Univ, Dwight Look Coll Engn, Zachry Dept Civil Engn, College Stn, TX 77843 USA. RP Wang, BX (reprint author), Texas A&M Univ, Dwight Look Coll Engn, Zachry Dept Civil Engn, 3136 TAMU, College Stn, TX 77843 USA. EM bwang@civil.tamu.edu NR 19 TC 1 Z9 1 U1 2 U2 4 PU NATL ACAD SCIENCES PI WASHINGTON PA 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA SN 0361-1981 EI 2169-4052 J9 TRANSPORT RES REC JI Transp. Res. Record PY 2013 IS 2330 BP 39 EP 46 DI 10.3141/2330-06 PG 8 WC Engineering, Civil; Transportation; Transportation Science & Technology SC Engineering; Transportation GA 298MM UT WOS:000330328000007 ER PT S AU Whipps, GT Ertin, E Moses, RL AF Whipps, Gene T. Ertin, Emre Moses, Randolph L. GP IEEE TI DISTRIBUTED DETECTION WITH COLLISIONS IN A RANDOM, SINGLE-HOP WIRELESS SENSOR NETWORK SO 2013 IEEE INTERNATIONAL CONFERENCE ON ACOUSTICS, SPEECH AND SIGNAL PROCESSING (ICASSP) SE International Conference on Acoustics Speech and Signal Processing ICASSP LA English DT Proceedings Paper CT IEEE International Conference on Acoustics, Speech, and Signal Processing (ICASSP) CY MAY 26-31, 2013 CL Vancouver, CANADA SP Inst Elect & Elect Engineers, Inst Elect & Elect Engineers Signal Proc Soc DE Distributed detection; random access sensor network AB We consider the problem of distributed detection in a large network of sensors under network communication constraints. Sensor nodes are randomly deployed and follow a random sleep/wake schedule. When awake, sensor nodes perform local detection tests and communicate detections over a multiple-access channel to a fusion center. The fusion center can detect both successful communications and communication collisions in the channel. We show that the optimum fusion rule is a weighted sum of the number of detections received and the number of collisions detected by the fusion node. We derive analytical expressions that characterize the performance of the system. Simulation examples compare theoretical predictions with numerical results. C1 [Whipps, Gene T.] US Army Res Lab, Adelphi, MD 20783 USA. [Whipps, Gene T.; Ertin, Emre; Moses, Randolph L.] Ohio State Univ, Dept ECE, Columbus, OH 43210 USA. RP Whipps, GT (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. FU U.S. Army Research Laboratory; ARO [W911NF-11-1-0391] FX The research reported here was partially supported by the U.S. Army Research Laboratory and by a grant from ARO, W911NF-11-1-0391. NR 8 TC 3 Z9 3 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1520-6149 BN 978-1-4799-0356-6 J9 INT CONF ACOUST SPEE PY 2013 BP 4603 EP 4607 PG 5 WC Acoustics; Engineering, Electrical & Electronic SC Acoustics; Engineering GA BJQ19 UT WOS:000329611504153 ER PT J AU Dretsch, MN Coldren, RL Kelly, MP Parish, RV Russell, ML AF Dretsch, Michael N. Coldren, Rodney L. Kelly, Mark P. Parish, Robert V. Russell, Michael L. TI No Effect of Deployment Environment in Establishing Baseline Neurocognitive Scores in US Army Soldiers SO APPLIED NEUROPSYCHOLOGY-ADULT LA English DT Article DE ANAM; baseline; deployment; military; neurocognitive testing ID SPORTS-RELATED CONCUSSION; NEUROPSYCHOLOGICAL ASSESSMENT; PERFORMANCE AB With heavy reliance on neurocognitive testing for concussion status assessments in the U.S. warfighter, there is a need to investigate the impact of testing environment on neurocognitive functioning. The current study compared scores on computerized neurocognitive tests of 166 soldiers who were deployed to Iraq. Predeployment baseline scores (n = 53) were compared to baseline scores collected while deployed (n = 113) on the battery of tests. There was no significant difference between baseline scores acquired from the predeployment group versus the deployed group. Furthermore, only one subtest revealed a significant difference in change scores from the follow-up test session when comparing the location of initial baseline testing. The results suggest that testing environment does not significantly influence baseline neurocognitive testing. The findings also provide support for the use of neurocognitive testing in a deployment environment. C1 [Dretsch, Michael N.] US Army Aeromed Res Lab, Warfighter Hlth Div, Ft Rucker, AL 36362 USA. [Coldren, Rodney L.] Uniformed Serv Univ Hlth Sci, Dept Prevent Med & Biometr, Bethesda, MD 20814 USA. [Kelly, Mark P.] Walter Reed Natl Mil Med Ctr, Dept Psychol, Neuropsychol Hlth Serv Assessment Div, Bethesda, MD USA. [Parish, Robert V.] Landstuhl Reg Med Ctr, Landstuhl, Germany. [Russell, Michael L.] Off Surgeon Gen, Rehabil & Reintegrat Div, San Antonio, TX USA. RP Dretsch, MN (reprint author), US Army Aeromed Res Lab, Warfighter Hlth Div, 6901 Farrel Rd, Ft Rucker, AL 36362 USA. EM Michael.dretsch@us.army.mil FU U.S. Army Medical Research Acquisition Activity [W81XWIH-09-2-0057] FX The authors acknowledge the assistance of numerous individuals whose efforts were critical in the performance of this study. We thank SSG David Lopez and SGT Pedro Cruz of the U.S. Army Aeromedical Research Laboratory for their diligent data collection efforts, and Cara Olsen, Ph.D., of Uniformed Services University for the Health Sciences for assistance with the statistical analyses. This work was supported by the U.S. Army Medical Research Acquisition Activity (W81XWIH-09-2-0057). NR 14 TC 2 Z9 2 U1 0 U2 2 PU PSYCHOLOGY PRESS PI HOVE PA 27 CHURCH RD, HOVE BN3 2FA, EAST SUSSEX, ENGLAND SN 0908-4282 EI 1532-4826 J9 APPL NEUROPSYCH-ADUL JI Appl. Neuropsychol.-Adult PY 2013 VL 20 IS 4 BP 272 EP 276 DI 10.1080/09084282.2012.715110 PG 5 WC Clinical Neurology; Psychology SC Neurosciences & Neurology; Psychology GA 298ST UT WOS:000330345400006 ER PT J AU Tang, KZ Liu, X Harper, SL Steevens, JA Xu, R AF Tang, Kaizhi Liu, Xiong Harper, Stacey L. Steevens, Jeffery A. Xu, Roger TI NEIMiner: nanomaterial environmental impact data miner SO INTERNATIONAL JOURNAL OF NANOMEDICINE LA English DT Article DE nanomaterial environmental impact; data integration; data management; content management system; data mining; modeling; model composition AB As more engineered nanomaterials (eNM) are developed for a wide range of applications, it is crucial to minimize any unintended environmental impacts resulting from the application of eNM. To realize this vision, industry and policymakers must base risk management decisions on sound scientific information about the environmental fate of eNM, their availability to receptor organisms (eg, uptake), and any resultant biological effects (eg, toxicity). To address this critical need, we developed a model-driven, data mining system called NEIMiner, to study nanomaterial environmental impact (NEI). NEIMiner consists of four components: NEI modeling framework, data integration, data management and access, and model building. The NEI modeling framework defines the scope of NEI modeling and the strategy of integrating NEI models to form a layered, comprehensive predictability. The data integration layer brings together heterogeneous data sources related to NEI via automatic web services and web scraping technologies. The data management and access layer reuses and extends a popular content management system (CMS), Drupal, and consists of modules that model the complex data structure for NEI-related bibliography and characterization data. The model building layer provides an advanced analysis capability for NEI data. Together, these components provide significant value to the process of aggregating and analyzing large-scale distributed NEI data. A prototype of the NEIMiner system is available at http://neiminer.i-a-i.com/. C1 [Tang, Kaizhi; Liu, Xiong; Xu, Roger] Intelligent Automat Inc, Rockville, MD 20855 USA. [Harper, Stacey L.] Oregon State Univ, Dept Environm & Mol Toxicol, Sch Chem Biol & Environm Engn, Corvallis, OR 97331 USA. [Steevens, Jeffery A.] US Army Engn Res & Dev Ctr, Vicksburg, MS USA. RP Tang, KZ (reprint author), Intelligent Automat Inc, 15400 Calhoun Dr,Suite 400, Rockville, MD 20855 USA. EM ktang@i-a-i.com; xliu09@gmail.com FU US Army Corps of Engineers [W912HZ-11-P-0009, W912HZ-12-C-0004]; National Institute of Environmental Health Sciences [ES017552-01A2, ES016896-01, P30 ES03850]; AFRL [FA8650-05-1-5041] FX The authors wish to thank the US Army Corps of Engineers for their support under research contract No W912HZ-11-P-0009 and W912HZ-12-C-0004; National Institute of Environmental Health Sciences grants ES017552-01A2, ES016896-01 and P30 ES03850; and AFRL FA8650-05-1-5041. An earlier version of this paper was presented at the Institute of Electrical and Electronics Engineers (IEEE) Workshop on Nanoinformatics for Biomedicine, in conjunction with the 2012 IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2012). NR 11 TC 6 Z9 6 U1 0 U2 16 PU DOVE MEDICAL PRESS LTD PI ALBANY PA PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND SN 1178-2013 J9 INT J NANOMED JI Int. J. Nanomed. PY 2013 VL 8 SU 1 BP 15 EP 29 DI 10.2147/IJN.S40974 PG 15 WC Nanoscience & Nanotechnology; Pharmacology & Pharmacy SC Science & Technology - Other Topics; Pharmacology & Pharmacy GA 293MZ UT WOS:000329977200003 PM 24098076 ER PT J AU Liu, X Tang, KZ Harper, S Harper, B Steevens, JA Xu, R AF Liu, Xiong Tang, Kaizhi Harper, Stacey Harper, Bryan Steevens, Jeffery A. Xu, Roger TI Predictive modeling of nanomaterial exposure effects in biological systems SO INTERNATIONAL JOURNAL OF NANOMEDICINE LA English DT Article DE nanomaterial exposure effects; biological response; toxicity; embryonic zebrafish; data mining; numerical prediction ID IN-VIVO; EMBRYONIC ZEBRAFISH; DNA NANOPARTICLES; TOXICITY; PARTICLES; DELIVERY; VITRO; CELLS AB Background: Predictive modeling of the biological effects of nanomaterials is critical for industry and policymakers to assess the potential hazards resulting from the application of engineered nanomaterials. Methods: We generated an experimental dataset on the toxic effects experienced by embryonic zebrafish due to exposure to nanomaterials. Several nanomaterials were studied, such as metal nanoparticles, dendrimer, metal oxide, and polymeric materials. The embryonic zebrafish metric (EZ Metric) was used as a screening-level measurement representative of adverse effects. Using the dataset, we developed a data mining approach to model the toxic endpoints and the overall biological impact of nanomaterials. Data mining techniques, such as numerical prediction, can assist analysts in developing risk assessment models for nanomaterials. Results: We found several important attributes that contribute to the 24 hours post-fertilization (hpf) mortality, such as dosage concentration, shell composition, and surface charge. These findings concur with previous studies on nanomaterial toxicity using embryonic zebrafish. We conducted case studies on modeling the overall effect/impact of nanomaterials and the specific toxic endpoints such as mortality, delayed development, and morphological malformations. The results show that we can achieve high prediction accuracy for certain biological effects, such as 24 hpf mortality, 120 hpf mortality, and 120 hpf heart malformation. The results also show that the weighting scheme for individual biological effects has a significant influence on modeling the overall impact of nanomaterials. Sample prediction models can be found at http://neiminer.i-a-i.com/nei_models. Conclusion: The EZ Metric-based data mining approach has been shown to have predictive power. The results provide valuable insights into the modeling and understanding of nanomaterial exposure effects. C1 [Liu, Xiong; Tang, Kaizhi; Xu, Roger] Intelligent Automat Inc, Rockville, MD 20855 USA. [Harper, Stacey; Harper, Bryan] Oregon State Univ, Dept Environm & Mol Toxicol, Sch Chem Biol & Environm Engn, Corvallis, OR 97331 USA. [Steevens, Jeffery A.] Erdc, Environm Lab, Vicksburg, MS USA. RP Liu, X (reprint author), Intelligent Automat Inc, 15400 Calhoun Dr,Suite 400, Rockville, MD 20855 USA. EM xliu09@gmail.com FU US Army Corps of Engineers [W912HZ-11-P-0009, W912HZ-12-C-0004]; NIEHS [ES017552-01A2, ES016896-01, P30 ES03850]; AFRL [FA8650-05-1-5041] FX We wish to thank US Army Corps of Engineers for their support under research contract numbers W912HZ-11-P-0009 and W912HZ-12-C-0004; NIEHS grants ES017552-01A2, ES016896-01, and P30 ES03850; and AFRL FA8650-05-1-5041. We thank the reviewers for their valuable comments. We also thank Ms Nalini Krishnankutty for language copy editing. NR 38 TC 12 Z9 12 U1 0 U2 17 PU DOVE MEDICAL PRESS LTD PI ALBANY PA PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND SN 1178-2013 J9 INT J NANOMED JI Int. J. Nanomed. PY 2013 VL 8 SU 1 BP 31 EP 43 DI 10.2147/IJN.S40742 PG 13 WC Nanoscience & Nanotechnology; Pharmacology & Pharmacy SC Science & Technology - Other Topics; Pharmacology & Pharmacy GA 293MZ UT WOS:000329977200004 PM 24098077 ER PT S AU Adams, BL Sarkes, DA Finch, AS Hurley, MM Stratis-Cullum, D AF Adams, Bryn L. Sarkes, Deborah A. Finch, Amethist S. Hurley, Margaret M. Stratis-Cullum, Dimitra BE Cullum, BM McLamore, ES TI Biodiscovery of Aluminum Binding Peptides SO SMART BIOMEDICAL AND PHYSIOLOGICAL SENSOR TECHNOLOGY X SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Smart Biomedical and Physiological Sensor Technology X CY MAY 01-02, 2013 CL Baltimore, MD SP SPIE DE peptide; synthetic reagent; affinity reagent; bacterial display; biosensing; biomineralization; solid binding peptides; aluminum; biopanning ID COLI CELL-SURFACE; PERIPLASMIC PROTEIN; PHAGE DISPLAY; METAL; OXIDE; LIBRARIES; AFFINITY; MOTIF AB Cell surface peptide display systems are large and diverse libraries of peptides (7-15 amino acids) which are presented by a display scaffold hosted by a phage (virus), bacteria, or yeast cell. This allows the self-sustaining peptide libraries to be rapidly screened for high affinity binders to a given target of interest, and those binders quickly identified. Peptide display systems have traditionally been utilized in conjunction with organic-based targets, such as protein toxins or carbon nanotubes. However, this technology has been expanded for use with inorganic targets, such as metals, for biofabrication, hybrid material assembly and corrosion prevention. While most current peptide display systems employ viruses to host the display scaffold, we have recently shown that a bacterial host, Escherichia coli, displaying peptides in the ubiquitous, membrane protein scaffold eCPX can also provide specific peptide binders to an organic target. We have, for the first time, extended the use of this bacterial peptide display system for the biodiscovery of aluminum binding 15mer peptides. We will present the process of biopanning with macroscopic inorganic targets, binder enrichment, and binder isolation and discovery. C1 [Adams, Bryn L.; Sarkes, Deborah A.; Finch, Amethist S.; Hurley, Margaret M.; Stratis-Cullum, Dimitra] US Army Res Lab, Adelphi, MD 20783 USA. RP Adams, BL (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. NR 40 TC 0 Z9 0 U1 3 U2 20 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9510-5 J9 PROC SPIE PY 2013 VL 8719 AR 871909 DI 10.1117/12.2015936 PG 12 WC Engineering, Biomedical; Optics; Physics, Applied SC Engineering; Optics; Physics GA BJQ21 UT WOS:000329624600002 ER PT S AU Finch, AS Bickford, JR Conn, MA Coppock, MB Sarkes, DA Stratis-Cullum, DN AF Finch, Amethist S. Bickford, Justin R. Conn, Marvin A. Coppock, Matthew B. Sarkes, Deborah A. Stratis-Cullum, Dimitra N. BE Cullum, BM McLamore, ES TI Towards a modular, robust, and portable sensing platform for biological and point of care diagnostics SO SMART BIOMEDICAL AND PHYSIOLOGICAL SENSOR TECHNOLOGY X SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Smart Biomedical and Physiological Sensor Technology X CY MAY 01-02, 2013 CL Baltimore, MD SP SPIE DE Point of Care; Molecular Recognition; Hand-Held Device; Smart Phone; Ubiquitous Sensing ID SITU CLICK CHEMISTRY; BACTERIAL DISPLAY AB The ability to conveniently and immediately test and diagnose in a diverse and rapidly changing environment is critical for field diagnostics. Smart biomedical sensors employ many different diagnostic/therapeutic methodologies; however, an ideal system would include the ability for results to be shared instantaneously with all members of the team through a software interface. We discuss our efforts towards the development and use of a robust, mobile platform (Android-based smart phone) that incorporates stable molecular recognition elements in sensor development. The inexpensive, compact, robust, archival, and portable design is ideal for rapid field diagnostics. C1 [Finch, Amethist S.; Bickford, Justin R.; Conn, Marvin A.; Coppock, Matthew B.; Sarkes, Deborah A.; Stratis-Cullum, Dimitra N.] US Army Res Lab, Sensors & Elect Devices Directorate, Adelphi, MD 20783 USA. RP Finch, AS (reprint author), US Army Res Lab, Sensors & Elect Devices Directorate, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 20 TC 0 Z9 0 U1 1 U2 6 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9510-5 J9 PROC SPIE PY 2013 VL 8719 AR 87190P DI 10.1117/12.2014766 PG 7 WC Engineering, Biomedical; Optics; Physics, Applied SC Engineering; Optics; Physics GA BJQ21 UT WOS:000329624600017 ER PT S AU Hurley, MM Sellers, MS AF Hurley, Margaret M. Sellers, Michael S. BE Cullum, BM McLamore, ES TI Prediction of Protein-Peptide Interactions: Application of the XPairIt API to anthrax lethal factor and substrates SO SMART BIOMEDICAL AND PHYSIOLOGICAL SENSOR TECHNOLOGY X SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Smart Biomedical and Physiological Sensor Technology X CY MAY 01-02, 2013 CL Baltimore, MD SP SPIE DE anthrax lethal factor; peptide binder; flexible docking; in silico design ID MOLECULAR-DYNAMICS; STRUCTURAL BASIS; SIMULATIONS; SELECTIVITY AB As software and methodology develop, key aspects of molecular interactions such as detailed energetics and flexibility are continuously better represented in docking simulations. In the latest iteration of the XPairIt API and Docking Protocol, we perform a blind dock of a peptide into the cleavage site of the Anthrax lethal factor (LF) metalloprotein. Molecular structures are prepared from RCSB:1JKY and we demonstrate a reasonably accurate docked peptide through analysis of protein motion and, using NCI Plot, visualize and characterize the forces leading to binding. We compare our docked structure to the 1JKY crystal structure and the more recent 1PWV structure, and discuss both captured and overlooked interactions. Our results offer a more detailed look at secondary contact and show that both van der Waals and electrostatic interactions from peptide residues further from the enzyme's catalytic site are significant. C1 [Hurley, Margaret M.; Sellers, Michael S.] US Army Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. RP Hurley, MM (reprint author), US Army Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. EM Margaret.m.hurley12.civ@mail.mil NR 25 TC 0 Z9 0 U1 0 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9510-5 J9 PROC SPIE PY 2013 VL 8719 AR 87190A DI 10.1117/12.2014767 PG 11 WC Engineering, Biomedical; Optics; Physics, Applied SC Engineering; Optics; Physics GA BJQ21 UT WOS:000329624600003 ER PT S AU Sarkar, SK Li, L Backer, MV Backer, JM Kumar, J AF Sarkar, Suproteem K. Li, Lian Backer, Marina V. Backer, Joseph M. Kumar, Jayant BE Cullum, BM McLamore, ES TI Development and characterization of two-photon fluorescent miniemulsion nanoparticles for targeted cancer drug delivery SO SMART BIOMEDICAL AND PHYSIOLOGICAL SENSOR TECHNOLOGY X SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Smart Biomedical and Physiological Sensor Technology X CY MAY 01-02, 2013 CL Baltimore, MD SP SPIE DE Two-photon fluorescence; nanoparticles; miniemulsion; targeted drug delivery; cancer treatment; dynamic light scattering; fluorescence microscopy ID MICROSCOPY; EXCITATION; POLYMER; DOTS AB Side effects of chemotherapy are major problems associated with current cancer treatment. An effective way to minimize these side effects and improve the efficacy of cancer treatment is to deliver drugs specifically targeted to tumors. This can be achieved by encapsulating chemotherapy drugs inside nanoparticles that aggregate in tumors due to the enhanced permeability and retention effect. In order to monitor the delivery of nanoparticle-drug conjugates, it is important to develop systems that can image the nanoparticles. Since two-photon fluorescent probes can lead to significant reduction of background fluorescence compared to single photon fluorescent probes, two-photon fluorescent nanoparticles were developed through the miniemulsion process, using a conjugated polymer-poly [2-(3-thienyl)ethanol butoxycarbonyl-methyl urethane])-and two surfactants-sodium dodecyl sulfate (SDS) and cetyl trimethylammonium bromide (CTAB). Nanoparticle size decreased as surfactant concentration increased, and particle size remained constant for surfactant concentrations above the critical micellar concentration (CMC), which was 8.2 mu M for SDS and 1 mu M for CTAB. The average size of the nanoparticles with surfactants at CMC was 31.67 nm for SDS nanoparticles and 25.60 nm for CTAB nanoparticles. Both nanoparticle systems exhibited strong one-photon and two-photon fluorescent signals. Fluorescence microscopy demonstrated these nanoparticles were able to penetrate rat cardiomyocytes. The results suggest these nanoparticles may potentially be used for high-contrast cell imaging. C1 [Sarkar, Suproteem K.] Conestoga High Sch, 200 Irish Rd, Berwyn, PA 19312 USA. [Sarkar, Suproteem K.; Kumar, Jayant] Univ Massachusetts Lowell, Ctr Adv Mat, Lowell, MA 01854 USA. [Li, Lian] US Army Natick Soldier Res, Dev & Engn Ctr, Natick, MA 01760 USA. [Backer, Marina V.; Backer, Joseph M.] Sibtech Inc, Newington, CT 06111 USA. [Kumar, Jayant] Univ Massachusetts Lowell, Dept Phys, Lowell, MA 01854 USA. RP Sarkar, SK (reprint author), Conestoga High Sch, 200 Irish Rd, Berwyn, PA 19312 USA. NR 14 TC 0 Z9 0 U1 0 U2 4 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9510-5 J9 PROC SPIE PY 2013 VL 8719 AR UNSP 87190T DI 10.1117/12.2018191 PG 9 WC Engineering, Biomedical; Optics; Physics, Applied SC Engineering; Optics; Physics GA BJQ21 UT WOS:000329624600019 ER PT S AU Servinsky, MD Germane, K Gerlach, ES Tsao, CY Byrd, CM Sund, CJ Bentley, WE AF Servinsky, Matthew D. Germane, Katherine Gerlach, Elliot S. Tsao, Chen-Yu Byrd, Christopher M. Sund, Christian J. Bentley, William E. BE Cullum, BM McLamore, ES TI Developing a Cell-Based Sensor for the Detection of Autoinducer-2' SO SMART BIOMEDICAL AND PHYSIOLOGICAL SENSOR TECHNOLOGY X SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Smart Biomedical and Physiological Sensor Technology X CY MAY 01-02, 2013 CL Baltimore, MD SP SPIE DE quorum sensing; Autoinducer-2 (AI-2); sensor cell; biofilm ID CYAN FLUORESCENT PROTEIN; ESCHERICHIA-COLI; DIRECTED EVOLUTION; VIBRIO-HARVEYI; INTERSPECIES COMMUNICATION; BIOFILM FORMATION; GENE-EXPRESSION; BACTERIA; SYSTEM; AL-2 AB Bacteria use an intricate set of communication systems for sensing and interpreting environmental cues that coordinate population-based behavior. Quorum sensing is one of these systems, and it involves the production, release, and detection of small chemical signaling molecules. Recent research has revealed the role of quorum sensing molecules in the control of microbial activities such as biofilm formation. In this presentation we outline the development of a recombinant E. coli cell-based sensor for detection of the quorum sensing molecule Autoinducer-2 (AI-2), as well as engineering strategies to remove sugar and anoxic inhibition of the strain. C1 [Servinsky, Matthew D.; Germane, Katherine; Gerlach, Elliot S.; Sund, Christian J.] US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. [Byrd, Christopher M.] Univ Maryland, College Pk, MD 20742 USA. RP Servinsky, MD (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. OI germane, katherine/0000-0002-5191-2670 NR 32 TC 0 Z9 0 U1 1 U2 5 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9510-5 J9 PROC SPIE PY 2013 VL 8719 AR UNSP 871903 DI 10.1117/12.2016601 PG 8 WC Engineering, Biomedical; Optics; Physics, Applied SC Engineering; Optics; Physics GA BJQ21 UT WOS:000329624600001 ER PT S AU Tolmachoff, ED Allmon, WR Waits, CM AF Tolmachoff, E. D. Allmon, W. R. Waits, C. M. GP IOP TI A Method for Microscale Combustion of Near Stoichiometric Energy Dense Liquid Fuel Mixtures SO 13TH INTERNATIONAL CONFERENCE ON MICRO AND NANOTECHNOLOGY FOR POWER GENERATION AND ENERGY CONVERSION APPLICATIONS (POWERMEMS 2013) SE Journal of Physics Conference Series LA English DT Proceedings Paper CT 13th International Conference on Micro- and Nano-Technology for Power Generation and Energy Conversion Applications (PowerMEMS) CY DEC 03-06, 2013 CL Imperial Coll London, London, ENGLAND SP Univ Southampton HO Imperial Coll London ID HETERO-/HOMOGENEOUS COMBUSTION; CATALYTIC MICROREACTORS; CONFINEMENT; OXIDATION; STABILITY; PROPANE AB This paper reports on the potential of a heterogeneous/homogeneous (HH) reactor for use as a fuel-flexible heat source, meeting the needs of the next generation of high temperature thermal-to-electric (TEC) portable power converters. In this class of reactor, low activation energy catalytic reactions provide a means to stabilize high activation energy homogeneous reactions. Diffusion limited surface reactions play a critical role in HH reactor operation. Surface conversion must be sufficiently fast to generate the high temperatures (similar to 1000 K) necessary to initiate gas phase reactions. Therefore, fuel diffusivity and the reactor dimension are important parameters in governing HH reactor operation. We examine the performance of an HH reactor fuelled by propane and n-dodecane, representing two extremes of liquid hydrocarbon diffusivity, as a function of confining reactor dimension. Unburned fuel/air mixtures are close to stoichiometric, which is an important factor in minimizing the amount of excess air and, therefore, balance of plant energy costs. At moderate levels of confinement, the reactor is capable producing high, uniform temperatures for both fuels. C1 [Tolmachoff, E. D.; Allmon, W. R.; Waits, C. M.] US Army Res Lab, Sensors & Elect Devices Directorate, Adelphi, MD 20912 USA. RP Tolmachoff, ED (reprint author), US Army Res Lab, Sensors & Elect Devices Directorate, 2800 Powder Mill Rd, Adelphi, MD 20912 USA. EM erik.d.tolmachoff.ctr@mail.mil NR 9 TC 0 Z9 0 U1 0 U2 8 PU IOP PUBLISHING LTD PI BRISTOL PA DIRAC HOUSE, TEMPLE BACK, BRISTOL BS1 6BE, ENGLAND SN 1742-6588 J9 J PHYS CONF SER PY 2013 VL 476 AR 012074 DI 10.1088/1742-6596/476/1/012074 PG 5 WC Energy & Fuels; Engineering, Electrical & Electronic; Nanoscience & Nanotechnology; Physics, Applied SC Energy & Fuels; Engineering; Science & Technology - Other Topics; Physics GA BJO21 UT WOS:000329347500073 ER PT J AU Chowdhury, SC Haque, BZ Gillespie, JW Chantawansri, TL Rosch, T Karkkainen, RL AF Chowdhury, S. C. Haque, B. Z. (G). Gillespie, J. W., Jr. Chantawansri, T. L. Rosch, T. Karkkainen, R. L. BE Bakis, CE TI Molecular Simulations of Silica Surface in Presence of Water SO PROCEEDINGS OF THE AMERICAN SOCIETY FOR COMPOSITES LA English DT Proceedings Paper CT 28th Technical Conference of the American-Society-for-Composites CY SEP 09-11, 2013 CL Penn State Univ, Dept Engn Sci & Mech, State College, PA SP Amer Soc Composites HO Penn State Univ, Dept Engn Sci & Mech ID NANOPARTICLES; DYNAMICS AB In this paper, a silica (SiO2) surface in the presence of water has been studied using molecular dynamics (MD) simulations. Water and silica models have been created separately, relaxed and then put side by side to study the silica-water interface. All the intra- and inter-molecular interactions have been described by the reactive force field ReaxFF. From the molecular simulations, structural properties of water and silica, silica surface reactivity, diffusion of water molecule into silica have been investigated. For molecular simulations, open source MD code LAMMPS has been used. C1 [Chowdhury, S. C.] Univ Delaware, Ctr Composite Mat UD CCM, Newark, DE 19716 USA. [Haque, B. Z. (G).] UD CCM, Dept Mech Engn, Newark, DE 19716 USA. [Gillespie, J. W., Jr.] UD CCM, Dept Mech Engn, Dept Civil & Environm Engn, Dept Mat Sci & Engn, Newark, DE 19716 USA. [Chantawansri, T. L.; Rosch, T.; Karkkainen, R. L.] US Army, Res Lab ARL APG, Aberdeen Proving Ground, MD 21005 USA. RP Chowdhury, SC (reprint author), Univ Delaware, Ctr Composite Mat UD CCM, Newark, DE 19716 USA. FU [W911NF-12-2-0022] FX Research was sponsored by the Army Research Laboratory and was accomplished under Cooperative Agreement Number W911NF-12-2-0022. The views and conclusions contained in this document are those of the authors and should not be interpreted as representing the official policies, either expressed or implied, of the Army Research Laboratory or the U.S. Government. The U.S. Government is authorized to reproduce and distribute reprints for Government purposes notwithstanding any copyright notation herein. Also the crystalline silica structure provided by ARL-APG is gratefully acknowledged. NR 19 TC 0 Z9 0 U1 1 U2 10 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-107-2 PY 2013 PG 12 WC Materials Science, Composites SC Materials Science GA BJN63 UT WOS:000329309500116 ER PT J AU Dwivedi, A Dalzell, MW Long, LR Slusarski, KA Fossey, SA Perry, J Wetzel, ED AF Dwivedi, A. Dalzell, M. W. Long, L. R. Slusarski, K. A. Fossey, S. A. Perry, J. Wetzel, E. D. BE Bakis, CE TI Continuous Filament Knit Aramids for Extremity Ballistic Protection SO PROCEEDINGS OF THE AMERICAN SOCIETY FOR COMPOSITES LA English DT Proceedings Paper CT 28th Technical Conference of the American-Society-for-Composites CY SEP 09-11, 2013 CL Penn State Univ, Dept Engn Sci & Mech, State College, PA SP Amer Soc Composites HO Penn State Univ, Dept Engn Sci & Mech ID SHORT-FIBER YARNS; CONSTITUTIVE THEORY; STAPLE YARN; MECHANICS AB Ballistic tests are performed on a continuous filament knitted aramid (CFKA) to determine the protective capabilities. CFKAs are candidates for implementation into garments that protect extremities, such as arms, legs, and the neck, from debris and other projectiles. These garments are expected to be designed at lower areal densities than conventional torso body armors, and have more demanding comfort requirements to accommodate flexible body joints. These unique requirements have prompted exploration of non-traditional armor materials such as knits and felts. The V-50 performance of a CFKA is compared to a woven aramid and commercial-off-the-shelf materials including: silk, polyester, Army Combat Uniform nylon-cotton blend fabric, staple yarn aramids, and aramid felts. Ballistic tests involve impacting each target multiple times with 0.22 caliber glass spheres in a pre-determined shot pattern. All targets are backed with ballistic gelatin and maximum likelihood estimation is used to calculate V50 values. Target areal densities range from approximately 200 g/m(2) to 1200 g/m(2). The results show that non-traditional materials like knits and felts can play an important role in extremity protection, and that unique design approaches are required for this emerging application area. Furthermore, the CFKA material appears to provide a unique combination of comfort and ballistic performance that may be well-suited to extremity protection applications. C1 [Dwivedi, A.; Long, L. R.; Slusarski, K. A.; Wetzel, E. D.] US Army Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. [Dalzell, M. W.] Def Sci & Technol Lab, Salisbury SP4 0JQ, Wilts, England. [Fossey, S. A.; Perry, J.] US Army, Natick Soldier RD&E Ctr, Mat & Fiber Phys Div, Natick, MA 01760 USA. RP Dwivedi, A (reprint author), US Army Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. NR 14 TC 0 Z9 0 U1 0 U2 4 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-107-2 PY 2013 PG 11 WC Materials Science, Composites SC Materials Science GA BJN63 UT WOS:000329309500053 ER PT J AU Emerson, R Lawrence, B Montgomery, A Safriet, S AF Emerson, R. Lawrence, B. Montgomery, A. Safriet, S. BE Bakis, CE TI Improvements to the Processing and Characterization of Needled Composite Laminates SO PROCEEDINGS OF THE AMERICAN SOCIETY FOR COMPOSITES LA English DT Proceedings Paper CT 28th Technical Conference of the American-Society-for-Composites CY SEP 09-11, 2013 CL Penn State Univ, Dept Engn Sci & Mech, State College, PA SP Amer Soc Composites HO Penn State Univ, Dept Engn Sci & Mech ID MECHANICAL-PROPERTIES; PRECURSOR; PROPERTY AB In the present investigation novel needle-processed S2-glass laminates are fabricated and several key failure modes are characterized. Double cantilever beam testing shows that mode I fracture toughness improves up to 270% compared to non-needled baseline material. In-plane compressive strength of needled material improves by up to 475%. In plane tensile strength shows mixed results, improving by 6% for moderate volume fractions of through-thickness reinforcement (TTR) and decreasing by 6% at larger volume fractions. Double lap shear tests show that interlaminar shear strength improves as much as 17% for TTR inserted at +/- 45 degrees relative to the laminate plane. X-ray micro-computed tomography (micro-CT) is used to investigate the unique 3D microstructure resulting from the needling process for 90 degrees TTR samples. The micro-CT reconstructions show that the dimensions of the disturbances of the in-plane fabric are significantly smaller than those imparted by the conventional tufting or stitching processes at each penetration site. Micro-CT reveals that some penetration sites are aggregates of closely spaced neighbors, resulting from the lack of precise spatial control with the needling process used in the present research. At these aggregate locations the in-plane disturbances are roughly equal in size to those from tufting/stitching. Modifications to the automated processing equipment are shown and discussed. The modifications allow better spatial control at the penetration sites and the ability to insert TTR at +/- 45 degrees relative to the laminate plane. C1 [Emerson, R.] US Army Res Lab, RDRL WMM A, Aberdeen Proving Ground, MD 21005 USA. [Lawrence, B.] Bowhead Sci & Technol, Belcamp, MD 21017 USA. [Montgomery, A.] Sci & Math Acad, Aberdeen Proving Ground, MD 21005 USA. [Safriet, S.] Air Force Res Lab, Mat & Mfg Directorate, Wright Patterson AFB, OH 45433 USA. RP Emerson, R (reprint author), US Army Res Lab, RDRL WMM A, Aberdeen Proving Ground, MD 21005 USA. NR 11 TC 0 Z9 0 U1 0 U2 6 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-107-2 PY 2013 PG 12 WC Materials Science, Composites SC Materials Science GA BJN63 UT WOS:000329309500065 ER PT J AU Haynes, R Shiao, M Liu, KC AF Haynes, R. Shiao, M. Liu, K. C. BE Bakis, CE TI Probabilistic Investigation of Composite Damage Progression and Failure Predictions SO PROCEEDINGS OF THE AMERICAN SOCIETY FOR COMPOSITES LA English DT Proceedings Paper CT 28th Technical Conference of the American-Society-for-Composites CY SEP 09-11, 2013 CL Penn State Univ, Dept Engn Sci & Mech, State College, PA SP Amer Soc Composites HO Penn State Univ, Dept Engn Sci & Mech ID SENSITIVITY-ANALYSIS; SIMULATIONS AB In this work, the uncertainty in progressive failure of a composite is studied. Damage progression and failure of a composite is analyzed deterministically using the Generalized Method of Cells. Monte Carlo simulations are performed to determine the probabilistic distribution of the failure load and associated reliability. A new probabilistic methodology is employed that uses a single set of sample results to conduct a probabilistic sensitivity analysis, which can identify parameters that have significant or negligible influence on failure load. The accuracy of this approach is investigated. The methodology is verified using Monte Carlo simulation. C1 [Haynes, R.; Shiao, M.] US Army Res Lab, 4603 Flare Loop, Aberdeen Proving Ground, MD 21005 USA. [Liu, K. C.] ORISE, Aberdeen Proving Ground, MD 21005 USA. RP Haynes, R (reprint author), US Army Res Lab, 4603 Flare Loop, Aberdeen Proving Ground, MD 21005 USA. NR 12 TC 0 Z9 0 U1 0 U2 1 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-107-2 PY 2013 PG 10 WC Materials Science, Composites SC Materials Science GA BJN63 UT WOS:000329309500051 ER PT J AU Henry, TC Bakis, CE Emerson, RP Riddick, JC AF Henry, T. C. Bakis, C. E. Emerson, R. P. Riddick, J. C. BE Bakis, CE TI Characterization of Compressively Loaded Filament Wound Composite Cylinders using Digital Image Correlation SO PROCEEDINGS OF THE AMERICAN SOCIETY FOR COMPOSITES LA English DT Proceedings Paper CT 28th Technical Conference of the American-Society-for-Composites CY SEP 09-11, 2013 CL Penn State Univ, Dept Engn Sci & Mech, State College, PA SP Amer Soc Composites HO Penn State Univ, Dept Engn Sci & Mech ID FIBER UNDULATIONS; STRENGTH AB In filament wound composites, the combination of undulated fiber architecture and a compliant matrix introduces unique challenges in the prediction of stiffness and strength using traditional laminated composite theories. Available micromechanical models incorporating the effects of undulated fibers on the stiffness and strength of filament wound composites have not been evaluated with high fidelity experimental data. Therefore, the objective of the current investigation is to measure full-field strains and out-of-plane displacements in compressively loaded filament wound cylinders made with rigid and flexible matrix materials. A series of [+/-theta/89/+/-theta] cylinders with multiple helical fiber angles, winding patterns, and matrix materials were manufactured and tested. Digital image correlation was used to measure outside surface displacements and strains. Axial and hoop direction strain fluctuations within with the filament winding pattern were found to be of the order of 20-30% of the mean values throughout the cylinders. Qualitatively, these fluctuations can be related to non-classical elastic couplings in the anti-symmetric regions of the pattern. Winding pattern affected compressive strength only in the flexible matrix composite, while it did not affect the axial modulus of elasticity appreciably in either material system. Failure of the cylinder occurred by fiber microbuckling, which initiated near the crossing of circumferential and helical cross-over bands. Based on a statistical analysis of surface strains in the local fiber coordinate system, it was determined that fiber-and shear-direction strains at incipient microbuckling were two to four times greater than their respective global counterparts. These results indicate the magnitude of strain concentration existing in the cylinders immediately before failure and highlight the importance of fiber-and shear-direction strains in the failure process. C1 [Henry, T. C.; Bakis, C. E.] Penn State Univ, University Pk, PA 16802 USA. [Emerson, R. P.; Riddick, J. C.] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Henry, TC (reprint author), Penn State Univ, University Pk, PA 16802 USA. NR 26 TC 0 Z9 0 U1 0 U2 1 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-107-2 PY 2013 PG 18 WC Materials Science, Composites SC Materials Science GA BJN63 UT WOS:000329309500054 ER PT J AU Pankow, M Yen, CF Waas, AM AF Pankow, M. Yen, C. F. Waas, A. M. BE Bakis, CE TI Comparison of 2D and 3D Composites to Confined Crush Loading SO PROCEEDINGS OF THE AMERICAN SOCIETY FOR COMPOSITES LA English DT Proceedings Paper CT 28th Technical Conference of the American-Society-for-Composites CY SEP 09-11, 2013 CL Penn State Univ, Dept Engn Sci & Mech, State College, PA SP Amer Soc Composites HO Penn State Univ, Dept Engn Sci & Mech ID WOVEN COMPOSITES; STRAIN-RATE AB Confined compression experiments are carried out to simulate the response of materials subjected to transverse impact loading. In this work, 2D woven composites are compared to 3D woven composites to see if the additional reinforcement through the thickness will affect the shear response through the thickness. Experimental results show that there is no loss in crush response from the insertion of Z-fibers into the material. C1 [Pankow, M.] N Carolina State Univ, Raleigh, NC 27695 USA. [Yen, C. F.] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. [Waas, A. M.] Univ Michigan, Composite Struct Lab, Ann Arbor, MI 48109 USA. RP Pankow, M (reprint author), N Carolina State Univ, Raleigh, NC 27695 USA. FU Army Research Laboratory FX The authors would like to thank the Army Research Laboratory for their continued financial support. NR 7 TC 0 Z9 0 U1 0 U2 0 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-107-2 PY 2013 PG 12 WC Materials Science, Composites SC Materials Science GA BJN63 UT WOS:000329309500063 ER PT J AU Zhang, D Waas, A Yen, CF AF Zhang, D. Waas, A. Yen, C. -F. BE Bakis, CE TI Flexural Response of 3D Hybrid Textile Composites SO PROCEEDINGS OF THE AMERICAN SOCIETY FOR COMPOSITES LA English DT Proceedings Paper CT 28th Technical Conference of the American-Society-for-Composites CY SEP 09-11, 2013 CL Penn State Univ, Dept Engn Sci & Mech, State College, PA SP Amer Soc Composites HO Penn State Univ, Dept Engn Sci & Mech ID COMPRESSIVE FAILURE; WOVEN COMPOSITES; FIBER COMPOSITES; STRENGTH; MECHANISMS; MICROMECHANICS; DEGRADATION; BEHAVIOR; MODEL AB This paper presents an experimental investigation on the flexural response of 3D hybrid textile composites subjected to quasi-static three-point bending. The term "hybrid" here refers to different constituent fibers, including carbon, glass, and Kevlar, that are integrally woven into a single preform. Three different hybrid architectures, manufactured by varying the percentages and lay-ups of each constituent fiber, were examined to understand the effect of hybridization and the resulting performance enhancement, including the bending modulus, flexural strength, and strain to failure. Although the experimental results show architecture-dependent flexural response, fiber tow kinking on the compressive side of the specimen is determined to be a strength limiting mechanism for this class of materials. C1 [Zhang, D.; Waas, A.] Univ Michigan, Dept Aerosp Engn, 1320 Beal Ave, Ann Arbor, MI 48109 USA. [Yen, C. -F.] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Zhang, D (reprint author), Univ Michigan, Dept Aerosp Engn, 1320 Beal Ave, Ann Arbor, MI 48109 USA. FU Army Research Laboratory FX The authors are grateful for the financial support from the Army Research Laboratory, Aberdeen Proving Ground, MD. NR 27 TC 0 Z9 0 U1 0 U2 1 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-107-2 PY 2013 PG 18 WC Materials Science, Composites SC Materials Science GA BJN63 UT WOS:000329309500064 ER PT J AU Weiss, V Ghoshal, A AF Weiss, V. Ghoshal, A. BE Chang, FK TI On the Search for Optimal Damage Precursors SO STRUCTURAL HEALTH MONITORING 2013, VOLS 1 AND 2 LA English DT Proceedings Paper CT 9th International Workshop on Structural Health Monitoring (IWSHM) CY SEP 10-12, 2013 CL Stanford Univ, Stanford, CA SP AF Off Sci Res, Army Res Lab, Off Naval Res, Boeing, Airbus, Embraer HO Stanford Univ AB A new approach to predict the service life of critical components via study of damage precursors is emerging and is the topic of this paper. To date most service life predictions are based on measurements of damage indicators and their growth towards criticality or failure, e.g. fatigue crack length, material loss due to corrosion or wear, etc. For many cases of concern, especially fatigue, the critical, direct damage indicator, D-i, i.e. crack length, increases exponentially towards criticality, roughly dD(i)/dN alpha D-i(n) where n can exceed 4. This makes lifetime estimates based on measurements of damage, e.g. around half-life, or even at 80 percent life, difficult and inaccurate, even for cases where the damage progress is well modeled and understood. To improve the accuracy and reliability of lifetime prediction, efforts are now underway to determine the state awareness of a critical component during service, based on property characterizations, in addition to the measurements of the direct damage indicators, such as crack length, acoustic emission, ultrasound signals, eddy current measurements, etc. These characterizations will include indirect damage indicators, i.e. precursors, and allied or affiliated damage indicators. Precursors, e.g. to fatigue crack formation, include electrical resistivity changes, dislocation distribution changes and crazing. For affiliated damage indicators residual stress relaxation or development, phase changes, electrical property (resistivity, dielectric constant, permeability), microstructural characterization, must be considered. The selection of the optimal combination of direct and indirect damage indicators will be application specific. For example for ultra-high strength steels and aluminum alloys, with high damage exponents n, where the critical crack length may also be very small and difficult to detect, measurements of reliable precursors and indirect damage indicators could significantly improve service life prediction. It is proposed to assess the efficacy of damage indicators on the basis of their D-i/D(f)vs.N-i/N-f, i.e. damage ratio vs. life fraction curves, (referred to as damage indicator ratio curves, or DIR curves) searching for indicators with DIR curves that best meet the needs of the application. C1 [Weiss, V.] Syracuse Univ, Syracuse, NY 13244 USA. [Weiss, V.; Ghoshal, A.] US Army Res Lab, Adelphi, MD 20783 USA. RP Weiss, V (reprint author), Syracuse Univ, Syracuse, NY 13244 USA. EM vweiss@syr.edu NR 16 TC 0 Z9 0 U1 0 U2 1 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-115-7 PY 2013 BP 27 EP + PG 2 WC Engineering, Civil; Engineering, Mechanical SC Engineering GA BJN59 UT WOS:000329292700003 ER PT J AU Hall, AJ Brennan, RE Ghoshal, A Coatney, M Haynes, R Bradley, N Weiss, V Tzeng, J AF Hall, A. J. Brennan, R. E. Ghoshal, A. Coatney, M. Haynes, R. Bradley, N. Weiss, V. Tzeng, J. BE Chang, FK TI Damage Precursor Investigation of Fiber Reinforced Composite Materials under Dynamic Cyclic Loads SO STRUCTURAL HEALTH MONITORING 2013, VOLS 1 AND 2 LA English DT Proceedings Paper CT 9th International Workshop on Structural Health Monitoring (IWSHM) CY SEP 10-12, 2013 CL Stanford Univ, Stanford, CA SP AF Off Sci Res, Army Res Lab, Off Naval Res, Boeing, Airbus, Embraer HO Stanford Univ ID POLYMERS AB Glass-epoxy composite structures are frequently used in many aerospace applications, such as landing gear struts, satellite frames, aircraft nose cones, and interior fuselage stiffeners. In glass fiber/epoxy composite systems, damage precursors such as micro-cracking have significant implications in impacting the performance and life span of the structure. As a consequence, it is necessary to gain a better understanding of the response under fatigue loading. The focus of this study is to identify the stress levels responsible for crazing, micro-crack formation and coalescence into macrocrack in S2 Glass Cycom381 Epoxy matrices (8 plies woven). Fatigue tests are performed at 1, 100, 1,000, 10,000, 100,000, and 1,000,000 cycles under tensile loading conditions (R=0.1). Strategies for monitoring the damage prior to, during, and after cyclic loading conditions include ultrasound and acoustic emission (AE) non-destructive evaluation techniques. AE is used during the fatigue loading tests to identify and localize real-time the presence of rupture, delamination, and crack formations. The high frequency ultrasound immersion technique is conducted for high fidelity interlaminar evaluation prior to fatigue testing. After each test, an examination of the fracture surface is conducted by several image characterization techniques including optical microscopy and Scanning Electron Microscopy (SEM). By this systematic evaluation, the phenomena of crazing, the propagation of micro-cracks, delaminations and other factors that lead to catastrophic failure are investigated. At the end of this study, an empirical framework is developed that maps the relationship between the sizing and location of the damage pre-cursors and the corresponding matrix/fiber degradation mechanisms. C1 [Hall, A. J.; Ghoshal, A.; Coatney, M.; Haynes, R.; Bradley, N.; Weiss, V.] US Army Res Lab, Vehicle Technol Directorate, Aberdeen Proving Ground, MD 21005 USA. RP Ghoshal, A (reprint author), US Army Res Lab, Vehicle Technol Directorate, Aberdeen Proving Ground, MD 21005 USA. EM anindya.ghoshal.civ@mail.mil NR 11 TC 0 Z9 0 U1 0 U2 7 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-115-7 PY 2013 BP 1778 EP 1785 PG 8 WC Engineering, Civil; Engineering, Mechanical SC Engineering GA BJN59 UT WOS:000329292700217 ER PT S AU Keller, CB AF Keller, Christian B. BE Slap, AL Smith, MT TI New Perspectives in Civil War Ethnic History and Their Implications for Twenty-First-Century Scholarship SO THIS DISTRACTED AND ANARCHICAL PEOPLE: NEW ANSWERS FOR OLD QUESTIONS ABOUT THE CIVIL WAR-ERA NORTH SE Norths Civil War LA English DT Article; Book Chapter C1 US Army War Coll, Carlisle, PA USA. RP Keller, CB (reprint author), US Army War Coll, Carlisle, PA USA. NR 0 TC 1 Z9 1 U1 0 U2 0 PU FORDHAM UNIV PRESS PI BRONX PA UNIV BOX L, BRONX, NY 10458 USA SN 1089-8719 BN 978-0-8232-4568-0; 978-0-8232-4569-7 J9 N CIVIL WAR PY 2013 BP 123 EP 141 PG 19 WC History SC History GA BJH74 UT WOS:000328271700009 ER PT J AU Tot, M Opsenica, DM Mitric, M Burnett, JC Gomba, L Bavari, S Solaja, BA AF Tot, Miklos Opsenica, Dejan M. Mitric, Milena Burnett, James C. Gomba, Laura Bavari, Sina Solaja, Bogdan A. TI New 9-aminoacridine derivatives as inhibitors of botulinum neurotoxins and P. falciparum malaria SO JOURNAL OF THE SERBIAN CHEMICAL SOCIETY LA English DT Article DE antiviral; BoNT/A; BoNT/B; antimalarial; aminoacridine ID PLASMODIUM-FALCIPARUM; IN-VITRO; ANTIMALARIAL ACTIVITY; ACRIDINE HYBRIDS; NEUROTRANSMITTER RELEASE; CHLOROQUINE-RESISTANT; PROTEASE INHIBITORS; PARALLEL SYNTHESIS; SEROTYPE-A; TOXIN AB Steroidal and adamantane aminoacridine derivatives were prepared and tested as both botulinum neurotoxin (BoNT) inhibitors and antimalarials.. Steroid-bound acridines provided good potency against both the BoNT/A and BoNT/B light chains (LCs). The observed inhibition of the BoNT/B LC by ca. 50 % is the highest attained inhibitory activity against this serotype by acridine-based compounds to date. With respect to the antimalarial activity, the adamantane acridines were the most potent derivatives (IC50 = 6-9 nM, SI>326), indicating that an adamantyl group is a better carrier than a steroidal motif for this indication. C1 [Tot, Miklos; Mitric, Milena; Solaja, Bogdan A.] Univ Belgrade, Fac Chem, Belgrade 11158, Serbia. [Opsenica, Dejan M.] Univ Belgrade, Inst Chem Technol & Met, Belgrade 11000, Serbia. [Burnett, James C.] SAIC Frederick Inc, Frederick Natl Lab Canc Res, Frederick, MD 21702 USA. [Gomba, Laura] US Army Med Res Inst Infect Dis, Dept Bacteriol, Frederick, MD 21702 USA. [Bavari, Sina] US Army Med Res Inst Infect Dis, Frederick, MD 21702 USA. RP Solaja, BA (reprint author), Univ Belgrade, Fac Chem, Studentski Trg 16,POB 51, Belgrade 11158, Serbia. EM bsolaja@chem.bg.ac.rs OI Solaja, Bogdan/0000-0002-9975-2725 FU National Institute of Allergy and Infectious Diseases (USA) [5-U01AI082051-02]; Ministry of Education, Science and Technological Development of the Republic of Serbia [172008]; Serbian Academy of Sciences and Arts; National Cancer Institute, National Institutes of Health (USA) [HHSN261200800001E] FX This research was supported by National Institute of Allergy and Infectious Diseases (USA) grant 5-U01AI082051-02, by the Ministry of Education, Science and Technological Development of the Republic of Serbia (Grant No. 172008) and the Serbian Academy of Sciences and Arts. Furthermore, for J.C.B., in compliance with SAIC-Frederick, Inc. contractual requirements: this project was funded in whole or in part with federal funds from the National Cancer Institute, National Institutes of Health (USA), under Contract No. HHSN261200800001E. The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services (USA), or the US Army, nor does the mention of trade names, commercial products, or organizations imply endorsement by the US Government, or the US Army. B.S. is grateful to WRAIR for providing the in vitro antimalarial results. NR 71 TC 3 Z9 3 U1 0 U2 3 PU SERBIAN CHEMICAL SOC PI BELGRADE PA KARNEGIJEVA 4, 11 120 BELGRADE, SERBIA SN 0352-5139 J9 J SERB CHEM SOC JI J. Serb. Chem. Soc. PY 2013 VL 78 IS 12 BP 1847 EP 1864 DI 10.2298/JSC130924112T PG 18 WC Chemistry, Multidisciplinary SC Chemistry GA 283QD UT WOS:000329261200003 ER PT J AU Le, DD Ghoshal, A Cuevas, E AF Le, D. D. Ghoshal, A. Cuevas, E. BE Chang, FK TI Condition-Based Maintenance Plus and Maintenance Credit Validation SO STRUCTURAL HEALTH MONITORING 2011: CONDITION-BASED MAINTENANCE AND INTELLIGENT STRUCTURES, VOL 2 SE Structural Health Monitoring LA English DT Proceedings Paper CT 8th International Workshop on Structural Health Monitoring CY SEP 13-15, 2011 CL Stanford Univ, Stanford, CA SP AF Off Sci Res, Army Res Off, Natl Sci Fdn, Off Naval Res HO Stanford Univ AB The Department of Defense (DoD) is currently maintaining the aircraft operability and functionality past the original design intention for many military aircraft. This practice imposes an additional burden on the inspection systems at the DoD logistic centers to ensure the aircraft in operation are airworthy and will be able to complete mission assignments for a specified period of time. Condition-Based Maintenance Plus (CBM+) has evolved into the U.S. Army leader priority program and becomes a critical technology for the future of the Army to reduce the logistic footprint, maximize the aircraft availability, and increase the component time on wing. To achieve these goals, the Army Research Laboratory (ARL) has initiated the CBM+ Science and Technology (S&T) Enterprise that spreads across ARL research organizations and supports the Army Research, Development, and Engineering Command CBM+ initiative in the Army fleet. The CBM+ S&T Enterprise has three Integrated Product Teams (IPTs), which focus on Hardware and Sensing, Prognostics and Diagnostics, and Data Transfer and Fusion Architecture technologies. The fourth IPT is the Technology Demonstration and Integration. It has been established that CBM, when joined with the system and/or sub-system prognostic capability (CBM+), could result in tremendous inspection savings, improved aircraft safety and availability, and decreased aircraft downtime and maintenance costs. Under these IPTs, diverse research efforts are being conducted and coordinated by the Technology Focus Working Groups (TFWGs) to combine diagnostics and prognostics capabilities. TFWGs concentrate on many technologies and processes including Structural Health Monitoring (SHM) and Maintenance Credit Validation. One of the challenges for researchers has been the development of the SHM capability that is not only effective and reliable but also relatively low cost and easy to install and maintain while performing the desired function of monitoring DoD systems and sub-systems for loss of structural integrity. SHM methods can be used to monitor the condition of critical structural components and, with other technologies, can determine the structural remaining useful life. As a result, potential maintenance credits, e.g., increased time-between-overhaul or fatigue life adjustment, can be formulated and proposed. Formulated maintenance credits are based on full understanding of physics of failure of monitored components, direct and/or indirect data that may contain some uncertainties, and methodologies that may be complex and advanced. This paper will document the ARL CBM+ S&T Enterprise strategies in supporting the Army CBM+ implementation goals and developing a process to validate maintenance credits or formulate maintenance-related decisions. Examples of CBM+ actions include the formulation of usage credits and early replacement of monitored parts before using up its component retirement life. C1 [Le, D. D.] Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Le, DD (reprint author), Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. NR 5 TC 0 Z9 0 U1 0 U2 3 PU DESTECH PUBLICATIONS, INC PI LANCASTER PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA BN 978-1-60595-053-2 J9 STRUCT HLTH MONIT PY 2013 BP 2485 EP 2492 PG 8 WC Engineering, Multidisciplinary SC Engineering GA BJH31 UT WOS:000328194500138 ER PT J AU Rushing, JF Mejias-Santiago, M Doyle, JD AF Rushing, John F. Mejias-Santiago, Mariely Doyle, Jesse D. TI Assessment of Warm-Mix Asphalt for Heavy Traffic Airfields SO TRANSPORTATION RESEARCH RECORD LA English DT Article ID MOISTURE DAMAGE; PERFORMANCE; MIXTURES AB This paper presents the results of tests of warm-mix asphalt (WMA) mixtures designed for airfield pavements. The study was conducted in two phases. The first phase included laboratory tests on 11 WMA technologies. The tests in Phase 2 were performed on three WMA mixtures and one hot-mix asphalt (HMA) mixture produced in an asphalt plant. The evaluation included performance tests to assess WMA susceptibility to permanent deformation and moisture damage compared with that of HMA produced with the same aggregate blend. Test results indicated that WMA potentially was a viable product for surface mixtures on airfield pavements. Although WMA exhibited poorer performance than BMA in moisture damage tests on laboratory-produced specimens, the plant-produced mix indicated little difference compared with HMA. Rutting potential for WMA was somewhat greater than for HMA for mixtures produced both in the laboratory and in an asphalt plant according to asphalt pavement analyzer and Hamburg wheel tracking tests. Differences in performance of WMA mixtures were not attributed to a specific WMA technology category. Variations in performance test results between laboratory-produced specimens and plant-produced specimens were noted and indicated a need to require performance testing as part of a comprehensive quality assurance plan. C1 [Rushing, John F.; Mejias-Santiago, Mariely; Doyle, Jesse D.] US Army Engineer Res & Dev Ctr, Airfields & Pavements Branch, Geotech & Struct Lab, CEERD GM A, Vicksburg, MS 39180 USA. RP Rushing, JF (reprint author), US Army Engineer Res & Dev Ctr, Airfields & Pavements Branch, Geotech & Struct Lab, CEERD GM A, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM john.f.rushing@erdc.dren.mil FU U.S. Air Force Civil Engineer Support Agency FX This research was funded by the U.S. Air Force Civil Engineer Support Agency. The authors thank Tim McCaffrey, Kevin Taylor, and Lance Warnock for their efforts with the laboratory testing and sampling of materials. Quint Mason, Tommy Carr, and Jeremy Beasley all provided assistance with the data collection and sampling during full-scale production. Permission to publish was granted by the director, Geotechnical and Structures Laboratory, U.S. Army Engineer Research and Development Center. NR 24 TC 7 Z9 7 U1 0 U2 7 PU NATL ACAD SCIENCES PI WASHINGTON PA 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA SN 0361-1981 J9 TRANSPORT RES REC JI Transp. Res. Record PY 2013 IS 2371 BP 41 EP 48 DI 10.3141/2371-05 PG 8 WC Engineering, Civil; Transportation; Transportation Science & Technology SC Engineering; Transportation GA 285RA UT WOS:000329411200006 ER PT S AU Conti, G Nelson, J Raymond, D AF Conti, Gregory Nelson, John Raymond, David BE Podins, K Stinissen, J Maybaum, M TI Towards a Cyber Common Operating Picture SO 2013 5TH INTERNATIONAL CONFERENCE ON CYBER CONFLICT (CYCON) SE International Conference on Cyber Conflict LA English DT Proceedings Paper CT 5th International Conference on Cyber Conflict (CYCON) CY JUN 04-07, 2013 CL Tallinn, ESTONIA SP NATO Cooperat Cyber Def Ctr Excellence, IEEE, Microsoft, Verint, Cisco, IXIA, IEEE, Estonia Sect DE cyber operations; cyber COP; cyber Common Operating Picture; CCOP; cyber situational awareness AB Commanders enjoy a refined common operating picture of the kinetic battlespace. While still imperfect, today's military command posts represent centuries of refinement and maturation enhanced by cutting-edge technology. Cyberspace's emergence as an operational domain, however, presents unresolved challenges to this status quo. Techniques for maintaining situational awareness and command and control of cyber operations, particularly joint cyber/kinetic operations, are ill-defined, and no current solutions provide military decision-makers with a comprehensive cyber common operating picture, or CCOP. This paper provides a framework for designing such systems. We focus on the problem of cyber-only operations as well as joint cyber-kinetic operations. Our analysis indicates that the CCOP problem is tractable, but non-trivial, requiring substantial effort realized through evolutionary and revolutionary research approaches. C1 [Conti, Gregory; Nelson, John; Raymond, David] US Mil Acad, Cyber Res Ctr, West Point, NY 10996 USA. RP Conti, G (reprint author), US Mil Acad, Cyber Res Ctr, West Point, NY 10996 USA. NR 26 TC 0 Z9 0 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2325-5366 BN 978-1-4799-0450-1 J9 INT CONF CYBER CONFL PY 2013 PG 17 WC Computer Science, Theory & Methods; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BJL32 UT WOS:000328827600016 ER PT S AU Raymond, D Conti, G Cross, T Fanelli, R AF Raymond, David Conti, Gregory Cross, Tom Fanelli, Robert BE Podins, K Stinissen, J Maybaum, M TI A Control Measure Framework to Limit Collateral Damage and Propagation of Cyber Weapons SO 2013 5TH INTERNATIONAL CONFERENCE ON CYBER CONFLICT (CYCON) SE International Conference on Cyber Conflict LA English DT Proceedings Paper CT 5th International Conference on Cyber Conflict (CYCON) CY JUN 04-07, 2013 CL Tallinn, ESTONIA SP NATO Cooperat Cyber Def Ctr Excellence, IEEE, Microsoft, Verint, Cisco, IXIA, IEEE, Estonia Sect DE cyber operations; malware controls; collateral damage; law of armed conflict AB With the recognition of cyberspace as a warfighting domain by the U. S. Department of Defense, we anticipate increased use of malicious software as weapons during hostilities between nation-states. Such conflict could occur solely on computer networks, but increasingly will be used in conjunction with traditional kinetic attack, or even to eliminate the need for kinetic attack. In either context, precise targeting and effective limiting of collateral damage from cyber weaponry are desired goals of any nation seeking to comply with the law of war. Since at least the Morris Worm, malicious software found in the wild has frequently contained mechanisms to target effectively, limit propagation, allow self-destruction, and minimize consumption of host resources to prevent detection and damage. This paper surveys major variants of malicious software from 1982 to present and synthesizes the control measures they contain that might limit collateral damage in future cyber weapons. As part of this work, we provide a framework for critical analysis of such measures. Our results indicate that a compelling framework for critical analysis emerges by studying these measures allowing classification of new forms of malware and providing insight into future novel technical mechanisms for limiting collateral damage. C1 [Raymond, David; Conti, Gregory] US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. [Cross, Tom] Lancope Inc, Alpharetta, GA USA. [Fanelli, Robert] US Cyber Command, Ft George G Meade, MD USA. RP Raymond, D (reprint author), US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. NR 29 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2325-5366 BN 978-1-4799-0450-1 J9 INT CONF CYBER CONFL PY 2013 PG 16 WC Computer Science, Theory & Methods; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BJL32 UT WOS:000328827600010 ER PT J AU Mion, TR Potrepka, DM Crowne, FJ Tauber, A Tidrow, SC AF Mion, Thomas R. Potrepka, Daniel M. Crowne, Frank J. Tauber, Arthur Tidrow, Steven C. TI Electrical and Structural Properties of Ba(Y3+,Sb5+)(0.05)Ti0.90O3 SO INTEGRATED FERROELECTRICS LA English DT Article; Proceedings Paper CT International Network of Advanced and Multifunctional Materials (INAMM) Symposium CY DEC 09-10, 2012 CL Pattaya, THAILAND DE Perovskite; phase transition; permittivity; lattice constant ID DIELECTRIC-PROPERTIES; BARIUM-TITANATE; PHASE-SHIFTER; FERROELECTRICS; BA1-XSRXTIO3; CAPACITORS; CRYSTALS AB The microwave ceramic Ba(Y,Sb)(0.05)Ti0.90O3, based upon random B-site dipole-like substitutions is structurally and electrically characterized over the temperature range -55 degrees C to 120 degrees C. X-ray diffraction information coupled together with scanning electron microscopy reveals that the material is single phase and has submicron grain sizes. Results show the tetragonal phase ranges from -30 degrees C to 200 degrees C, which is a broader temperature range than that of the parent material BaTiO3, 0 degrees C to 120 degrees C. The material Ba(Y,Sb)(0.05)Ti0.90O3 also has a diffuse relative high dielectric constant of about 10,000 that peaks at the orthorhombic-tetragonal structural phase transition around -30 degrees C. C1 [Mion, Thomas R.; Tidrow, Steven C.] Univ Texas Pan Amer, Dept Phys & Geol, Edinburg, TX 78539 USA. [Potrepka, Daniel M.; Crowne, Frank J.] US Army Res Lab, Adelphi, MD 20783 USA. RP Tidrow, SC (reprint author), Univ Texas Pan Amer, Dept Phys & Geol, Edinburg, TX 78539 USA. EM sctidrow@utpa.edu FU U.S. Army Research Laboratory; U.S. Army Research Office [W911NF-08-1-0353] FX This material is based upon work supported by, or in part by, the U.S. Army Research Laboratory and the U.S. Army Research Office under contract/grant number W911NF-08-1-0353. NR 19 TC 1 Z9 1 U1 0 U2 9 PU TAYLOR & FRANCIS LTD PI ABINGDON PA 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND SN 1058-4587 EI 1607-8489 J9 INTEGR FERROELECTR JI Integr. Ferroelectr. PD JAN 1 PY 2013 VL 148 IS 1 BP 17 EP 26 DI 10.1080/10584587.2013.851584 PG 10 WC Engineering, Electrical & Electronic; Physics, Applied; Physics, Condensed Matter SC Engineering; Physics GA 269NL UT WOS:000328247900002 ER PT J AU George, J AF George, Jemin GP IEEE TI Networked Sensing and Distributed Kalman-Bucy Filtering based on Dynamic Average Consensus SO 2013 9TH IEEE INTERNATIONAL CONFERENCE ON DISTRIBUTED COMPUTING IN SENSOR SYSTEMS (IEEE DCOSS 2013) LA English DT Proceedings Paper CT 9th IEEE International Conference on Distributed Computing in Sensor Systems (DCoSS) CY MAY 21-23, 2013 CL Cambridge, MA SP IEEE, IEEE Comp Soc, Assoc Comp Machinery ID SYSTEMS; AGENTS AB This paper presents the formulation of distributed Kalman-Bucy filter algorithm for a network of autonomous sensors, which is modeled as a connected undirected graph. Development of the distributed Kalman-Bucy filter is formulated as two average consensus problems in terms of weighted inverse of measurement noise covariance matrices and weighted measurements. The proposed algorithm utilizes the static average consensus protocol to solve the first consensus problem and the proportional-integral based dynamic average consensus protocol to solve the latter. The distributed Kalman-Bucy filter algorithm is optimal in the sense that the performance of the proposed algorithm asymptotically approaches that of a centralized filter. Numerical simulations are presented to demonstrate the performance of the proposed scheme. C1 US Army Res Lab, Adelphi, MD 20783 USA. RP George, J (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. EM jemin.george.civ@mail.mil NR 24 TC 0 Z9 0 U1 2 U2 3 PU IEEE COMPUTER SOC PI LOS ALAMITOS PA 10662 LOS VAQUEROS CIRCLE, PO BOX 3014, LOS ALAMITOS, CA 90720-1264 USA BN 978-0-7695-5041-1 PY 2013 BP 175 EP 182 DI 10.1109/DCOSS.2013.11 PG 8 WC Computer Science, Theory & Methods; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BJH39 UT WOS:000328213800021 ER PT J AU Shogan, BD Smith, DP Packman, AI Kelley, ST Landon, EM Bhangar, S Vora, GJ Jones, RM Keegan, K Stephens, B Ramos, T Kirkup, BC Levin, H Rosenthal, M Foxman, B Chang, EB Siegel, J Cobey, S An, G Alverdy, JC Olsiewski, PJ Martin, MO Marrs, R Hernandez, M Christley, S Morowitz, M Weber, S Gilbert, J AF Shogan, Benjamin D. Smith, Daniel P. Packman, Aaron I. Kelley, Scott T. Landon, Emily M. Bhangar, Seema Vora, Gary J. Jones, Rachael M. Keegan, Kevin Stephens, Brent Ramos, Tiffanie Kirkup, Benjamin C., Jr. Levin, Hal Rosenthal, Mariana Foxman, Betsy Chang, Eugene B. Siegel, Jeffrey Cobey, Sarah An, Gary Alverdy, John C. Olsiewski, Paula J. Martin, Mark O. Marrs, Rachel Hernandez, Mark Christley, Scott Morowitz, Michael Weber, Stephen Gilbert, Jack TI The Hospital Microbiome Project: Meeting report for the 2nd Hospital Microbiome Project, Chicago, USA, January 15th, 2013 SO STANDARDS IN GENOMIC SCIENCES LA English DT Article AB This report details the outcome of the 2nd Hospital Microbiome Project workshop held on January 15th at the University of Chicago, USA. This workshop was the final planning meeting prior to the start of the Hospital Microbiome Project, an investigation to measure and characterize the development of a microbial community within a newly built hospital at the University of Chicago. The main goals of this workshop were to bring together experts in various disciplines to discuss the potential hurdles facing the implementation of the project, and to allow brainstorming of potential synergistic project opportunities. C1 [Shogan, Benjamin D.; An, Gary; Alverdy, John C.; Christley, Scott] Univ Chicago Med, Dept Surg, Chicago, IL 60637 USA. [Smith, Daniel P.; Keegan, Kevin; Gilbert, Jack] Argonne Natl Lab, Argonne, IL 60439 USA. [Packman, Aaron I.] Northwestern Univ, Dept Civil & Environm Engn, Evanston, IL 60208 USA. [Kelley, Scott T.] San Diego State Univ, Dept Biol, San Diego, CA 92182 USA. [Landon, Emily M.; Marrs, Rachel; Weber, Stephen] Univ Chicago Med, Dept Med, Sect Infect Dis & Global Hlth, Chicago, IL 60637 USA. [Bhangar, Seema] Univ Calif Berkeley, Dept Civil & Environm Engn, Berkeley, CA 94720 USA. [Vora, Gary J.] Naval Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC 20375 USA. [Jones, Rachael M.] Univ Illinois, Sch Publ Hlth, Div Environm & Occupat Hlth Sci, Chicago, IL 60612 USA. [Stephens, Brent; Ramos, Tiffanie] IIT, Dept Civil Architectural & Environm Engn, Chicago, IL 60616 USA. [Kirkup, Benjamin C., Jr.] Walter Reed Army Inst Res, Dept Wound Infect, Silver Spring, MD 20910 USA. [Kirkup, Benjamin C., Jr.] Uniformed Serv Univ Hlth Sci, Dept Med, Bethesda, MD 20814 USA. [Levin, Hal] Bldg Ecol Res Grp, Santa Cruz, CA 95060 USA. [Rosenthal, Mariana; Foxman, Betsy] Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA. [Chang, Eugene B.] Univ Chicago Med, Dept Med, Chicago, IL 60637 USA. [Siegel, Jeffrey] Univ Toronto, Dept Civil Engn, Toronto, ON M5S 1A1, Canada. [Cobey, Sarah; Gilbert, Jack] Univ Chicago, Dept Ecol & Evolut, Chicago, IL 60637 USA. [Olsiewski, Paula J.] Alfred P Sloan Fdn, New York, NY 10111 USA. [Martin, Mark O.] Univ Puget Sound, Dept Biol, Tacoma, WA 98416 USA. [Hernandez, Mark] Univ Colorado, Dept Civil Environm & Architectural Engn, Boulder, CO 80309 USA. [Morowitz, Michael] Univ Pittsburgh, Childrens Hosp Pittsburgh UPMC, Sch Med, Pittsburgh, PA 15224 USA. RP Shogan, BD (reprint author), Univ Chicago Med, Dept Surg, Chicago, IL 60637 USA. RI Packman, Aaron/B-7085-2009; Foxman, Betsy/E-1836-2015; Kirkup, Benjamin/C-3610-2009; OI Kirkup, Benjamin/0000-0002-8722-6218; Vora, Gary/0000-0002-0657-8597 FU APSF; U.S. Dept. of Energy [DE-AC02-06CH11357] FX We acknowledge the APSF for funding this workshop. This work was supported in part by the U.S. Dept. of Energy under contract DE-AC02-06CH11357. NR 5 TC 3 Z9 3 U1 0 U2 20 PU GENOMIC STAND CONSORT PI EAST LANSING PA MICHIGAN STATE UNIV, GEEO GARRITY, DEPT MICROBIOL, 6162 BIOMED & PHYS SCI BLDG, EAST LANSING, MI 48824 USA SN 1944-3277 J9 STAND GENOMIC SCI JI Stand. Genomic Sci. PY 2013 VL 8 IS 3 BP 571 EP 579 DI 10.4056/sigs.4187859 PG 9 WC Genetics & Heredity; Microbiology SC Genetics & Heredity; Microbiology GA 270ML UT WOS:000328322400017 PM 24501640 ER PT S AU Weiss, S AF Weiss, Steven GP IEEE TI Using Metamaterials to Exploit Lateral Waves for RF Microwave Applications SO 2013 7TH EUROPEAN CONFERENCE ON ANTENNAS AND PROPAGATION (EUCAP) SE Proceedings of the European Conference on Antennas and Propagation LA English DT Proceedings Paper CT 7th European Conference on Antennas and Propagation (EuCAP) CY APR 08-12, 2013 CL Gothenburg, SWEDEN DE metamaterials; anisotropic Green's function; Hertzian Dipole AB In this paper, the excitation of lateral (surface) waves in a layered media consisting of a ground plane, a metamaterial layer and free space is investigated. It is presumed an effective media approximation yields the anisotropic constitutive parameters for the metamaterial layer. Using these approximations, Green's functions are developed for the electromagnetic fields resulting from a Hertzian dipole excitation located at the metamaterial and free space interface. As the formulation of the problem is accomplished in the spectral domain, the strength of the lateral waves is found from the residues of poles circled in the complex plane. This is first done for the case of an anisotropic media in the x- and y- directions (parallel to the ground plane). Because the unit cell patterning of the metamaterials gives the microwave designer increased flexibility, it is possible to undertake a similar analysis using anisotropic constitutive parameters expressed in cylindrical coordinates. This analysis is fundamental for applied microwave applications such as the realization of an antenna on a layered media and demonstrates the enormous design flexibility made possible for metamaterials. C1 Army Res Lab, Adelphi, MD 20783 USA. RP Weiss, S (reprint author), Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM steven.j.weiss14.civ@mail.mil NR 3 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2164-3342 BN 978-88-907018-3-2; 978-1-4673-2187-7 J9 PROC EUR CONF ANTENN PY 2013 BP 3946 EP 3947 PG 2 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BIA05 UT WOS:000327126003127 ER PT J AU Roach, KE Linberg, AA Raya, MA AF Roach, Kathryn E. Linberg, Alison A. Raya, Michele A. TI Developing and testing a new outcome measure SO JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT LA English DT Editorial Material C1 [Roach, Kathryn E.; Raya, Michele A.] Univ Miami, Miller Sch Med, Dept Phys Therapy, Coral Gables, FL 33124 USA. [Linberg, Alison A.] Walter Reed Army Med Ctr, Mil Adv Training Ctr, Washington, DC 20307 USA. RP Roach, KE (reprint author), Univ Miami, Miller Sch Med, Dept Phys Therapy, Coral Gables, FL 33124 USA. EM keroach@miami.edu NR 0 TC 0 Z9 0 U1 0 U2 2 PU JOURNAL REHAB RES & DEV PI BALTIMORE PA DEPT OF VETERANS AFFAIRS REHABIL RES & DEVELOP CTR 103 SOUTH GAY STREET, BALTIMORE, MD 21202-4051 USA SN 0748-7711 EI 1938-1352 J9 J REHABIL RES DEV JI J. Rehabil. Res. Dev. PY 2013 VL 50 IS 7 BP XVII EP XIX DI 10.1682/JRRD.2013.05.0112 PG 3 WC Rehabilitation SC Rehabilitation GA 257VM UT WOS:000327415900002 ER PT J AU Stoneman, PD Hooper, R Scoville, C AF Stoneman, Paul D. Hooper, Rebecca Scoville, Charles TI Implementing outcome measures-The military physical therapist's perspective SO JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT LA English DT Editorial Material C1 [Stoneman, Paul D.] Walter Reed Natl Mil Med Ctr, Bethesda, MD USA. [Hooper, Rebecca] Brooke Army Med Ctr, Ctr Intrepid, San Antonio, TX USA. [Scoville, Charles] Walter Reed Natl Mil Med Ctr, Mil Adv Training Ctr, Bethesda, MD USA. RP Stoneman, PD (reprint author), Walter Reed Natl Mil Med Ctr, Bethesda, MD USA. EM pstoneman@rmuohp.edu NR 0 TC 0 Z9 0 U1 0 U2 0 PU JOURNAL REHAB RES & DEV PI BALTIMORE PA DEPT OF VETERANS AFFAIRS REHABIL RES & DEVELOP CTR 103 SOUTH GAY STREET, BALTIMORE, MD 21202-4051 USA SN 0748-7711 EI 1938-1352 J9 J REHABIL RES DEV JI J. Rehabil. Res. Dev. PY 2013 VL 50 IS 7 BP XXI EP XXIV DI 10.1682/JRRD.2013.05.0113 PG 4 WC Rehabilitation SC Rehabilitation GA 257VM UT WOS:000327415900003 ER PT J AU Gailey, RS Gaunaurd, IA Raya, MA Roach, KE Linberg, AA Campbell, SM Jayne, DM Scoville, C AF Gailey, Robert S. Gaunaurd, Ignacio A. Raya, Michele A. Roach, Kathryn E. Linberg, Alison A. Campbell, Stuart M. Jayne, Daniel M. Scoville, Charles TI Development and reliability testing of the Comprehensive High-Level Activity Mobility Predictor (CHAMP) in male servicemembers with traumatic lower-limb loss SO JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT LA English DT Article DE agility; high-level activity; lower-limb loss; military personnel; mobility; OIF/OEF; outcome measures; reliability; traumatic amputation; Veterans ID STRENGTH; AGILITY; AFGHANISTAN; AMPUTATION; VALIDITY; PLAYERS; WOMEN; WAR; DETERMINANTS; CONFLICTS AB The opportunity for wounded servicemembers (SMs) to return to high-level activity and return to duty has improved with advances in surgery, rehabilitation, and prosthetic technology. As a result, there is now a need for a high-level mobility outcome measure to assess progress toward high-level mobility during and after rehabilitation. The purpose of this study was to develop and determine the reliability of a new outcome measure called the Comprehensive High-Level Activity Mobility Predictor (CHAMP). The CHAMP consists of the Single Limb Stance, Edgren Side Step Test, T-Test, and Illinois Agility Test. CHAMP reliability was determined for SMs with lower-limb loss (LLL) (interrater: n = 118; test-retest: n = 111) and without LLL (n = 97). A linear system was developed to combine the CHAMP items and produce a composite score that ranges from 0 to 40, with higher scores indicating better performance. Interrater and test-retest intraclass correlation coefficient values for the CHAMP were 1.0 and 0.97, respectively. A CHAMP score equal to or greater than 33 points is within the range for SMs without LLL. The CHAMP was found to be a safe and reliable measure of high-level mobility in SMs with traumatic LLL. C1 [Gailey, Robert S.; Gaunaurd, Ignacio A.] Miami Dept Vet Affairs Healthcare Syst, Funct Outcomes Res & Evaluat Ctr, Miami, FL USA. [Gailey, Robert S.; Raya, Michele A.; Roach, Kathryn E.] Univ Miami, Miller Sch Med, Dept Phys Therapy, Coral Gables, FL 33146 USA. [Linberg, Alison A.; Scoville, Charles] Walter Reed Army Med Ctr, Mil Adv Training Ctr, Washington, DC 20307 USA. [Campbell, Stuart M.] Brooke Army Med Ctr, Ctr Intrepid, San Antonio, TX USA. [Jayne, Daniel M.] Womack Army Med Ctr, Fayetteville, NC USA. RP Gailey, RS (reprint author), Univ Miami, Miller Sch Med, Dept Phys Therapy, 5915 Ponce de Leon Blvd,Plummer Bldg,5th Floor, Coral Gables, FL 33146 USA. EM rgailey@miami.edu OI Campbell, Stephen/0000-0002-2328-4136 FU Military Amputee Research Program; Telemedicine and Advanced Technology Research Center [W81XWH-06-2-0073]; U.S. Army Medical Research Acquisition Activity (Fort Detrick, Maryland) FX This material was based on work supported by the Military Amputee Research Program and the Telemedicine and Advanced Technology Research Center (Prime Award No. W81XWH-06-2-0073). The U.S. Army Medical Research Acquisition Activity (Fort Detrick, Maryland) is the awarding and administering acquisition office. It was administered by the Henry M. Jackson Foundation for the Advancement of Military Medicine and the South Florida Veterans Affairs Foundation for Research and Education. NR 42 TC 6 Z9 6 U1 0 U2 2 PU JOURNAL REHAB RES & DEV PI BALTIMORE PA DEPT OF VETERANS AFFAIRS REHABIL RES & DEVELOP CTR 103 SOUTH GAY STREET, BALTIMORE, MD 21202-4051 USA SN 0748-7711 EI 1938-1352 J9 J REHABIL RES DEV JI J. Rehabil. Res. Dev. PY 2013 VL 50 IS 7 BP 905 EP 918 DI 10.1682/JRRD.2012.05.0099 PG 14 WC Rehabilitation SC Rehabilitation GA 257VM UT WOS:000327415900007 PM 24301428 ER PT J AU Gailey, RS Scoville, C Gaunaurd, IA Raya, MA Linberg, AA Stoneman, PD Campbell, SM Roach, KE AF Gailey, Robert S. Scoville, Charles Gaunaurd, Ignacio A. Raya, Michele A. Linberg, Alison A. Stoneman, Paul D. Campbell, Stuart M. Roach, Kathryn E. TI Construct validity of Comprehensive High-Level Activity Mobility Predictor (CHAMP) for male servicemembers with traumatic lower-limb loss SO JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT LA English DT Article DE 6-minute walk test; agility; Amputee Mobility Predictor; CHAMP; construct validity; high-level mobility; lower-limb loss; military personnel; OIF/OEF; traumatic amputation ID 6-MINUTE WALK TEST; PERFORMANCE; AMPUTATION; BALANCE; INDIVIDUALS; AFGHANISTAN; CONFLICTS; VETERANS; AMPUTEES; ABILITY AB This study examined the convergent construct validity of a new performance-based assessment instrument called the Comprehensive High-Level Activity Mobility Predictor (CHAMP) as a measure of high-level mobility in service-members (SMs) with traumatic lower-limb loss (LLL). The study was completed by 118 SMs. Convergent construct validity of the CHAMP was established using the 6-minute walk test (6MWT) as a measure of overall mobility and physical function and the Amputee Mobility Predictor (AMP) as a measure of basic prosthetic mobility. The known group methods construct validity examined disparities in high-level mobility capability among SMs with different levels of LLL. The CHAMP score demonstrated a strong positive relationship between 6MWT distance (r = 0.80, p < 0.001) and AMP score (r = 0.87,p < 0.001), respectively. In addition, the CHAMP can discriminate between different levels of LLL. Study findings support the CHAMP as a valid performance-based assessment instrument of high-level mobility for SMs with traumatic LLL. C1 [Gailey, Robert S.; Gaunaurd, Ignacio A.] Miami Dept Vet Affairs Healthcare Syst, Funct Outcomes Res & Evaluat Ctr, Miami, FL USA. [Gailey, Robert S.; Gaunaurd, Ignacio A.; Raya, Michele A.; Roach, Kathryn E.] Univ Miami, Miller Sch Med, Dept Phys Therapy, Coral Gables, FL 33146 USA. [Scoville, Charles; Linberg, Alison A.; Stoneman, Paul D.] Walter Reed Army Med Ctr, Mil Adv Training Ctr, Washington, DC 20307 USA. [Campbell, Stuart M.] Brooke Army Med Ctr, Ctr Intrepid, San Antonio, TX USA. RP Gailey, RS (reprint author), Univ Miami, Miller Sch Med, Dept Phys Therapy, 5915 Ponce de Leon Blvd,Plummer Bldg,5th Floor, Coral Gables, FL 33146 USA. EM rgailey@miami.edu OI Campbell, Stephen/0000-0002-2328-4136 FU Military Amputee Research Program; Telemedicine and Advanced Technology Research Center [W81XWH-06-2-0073]; U.S. Army Medical Research Acquisition Activity, Fort Detrick, Maryland FX This material was based on work supported by the Military Amputee Research Program and the Telemedicine and Advanced Technology Research Center (Prime Award No. W81XWH-06-2-0073). The U.S. Army Medical Research Acquisition Activity, Fort Detrick, Maryland, is the awarding and administering acquisition office. It was administered by the Henry M. Jackson Foundation for the Advancement of Military Medicine Inc and the South Florida Veterans Affairs Foundation for Research and Education Inc. NR 42 TC 4 Z9 4 U1 1 U2 4 PU JOURNAL REHAB RES & DEV PI BALTIMORE PA DEPT OF VETERANS AFFAIRS REHABIL RES & DEVELOP CTR 103 SOUTH GAY STREET, BALTIMORE, MD 21202-4051 USA SN 0748-7711 EI 1938-1352 J9 J REHABIL RES DEV JI J. Rehabil. Res. Dev. PY 2013 VL 50 IS 7 BP 919 EP 930 DI 10.1682/JRRD.2012.05.0100 PG 12 WC Rehabilitation SC Rehabilitation GA 257VM UT WOS:000327415900008 PM 24301429 ER PT J AU Linberg, AA Roach, KE Campbell, SM Stoneman, PD Gaunaurd, IA Raya, MA Gomez-Orozco, C Gailey, RS AF Linberg, Alison A. Roach, Kathryn E. Campbell, Stuart M. Stoneman, Paul D. Gaunaurd, Ignacio A. Raya, Michele A. Gomez-Orozco, Carlos Gailey, Robert S. TI Comparison of 6-minute walk test performance between male Active Duty soldiers and servicemembers with and without traumatic lower-limb loss SO JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT LA English DT Article DE 6-minute walk test; amputation; amputee; endurance measure; functional testing; limb loss; performance measure; rehabilitation; US servicemembers; walk test ID TRANSTIBIAL AMPUTATION; PROSTHETIC KNEE; DYNAMIC BALANCE; GO TEST; AMPUTEES; INDIVIDUALS; RELIABILITY; PEOPLE; RESPONSIVENESS; CONFLICTS AB The rehabilitation of U.S. military servicemembers (SMs) who have sustained a traumatic loss of one or both lower limbs requires outcome measures that can assess their physical capabilities in comparison with their uninjured colleagues. Describing reference ranges for the 6-minute walk test (6MWT) in both populations will help clinicians develop appropriate goals for rehabilitation and document progress toward those goals. A convenience sample of 118 male U.S. SMs with and 97 without traumatic lower-limb loss participated in this study. All participants completed a 6MWT, and comparisons were made between SMs with and without limb loss and among the levels of limb loss. The SMs without lower-limb loss performed significantly better than all SMs with lower-limb loss. The SMs with transtibial limb loss performed significantly better than those with all other levels of limb loss. Statistically significant and clinically relevant differences were also noted between the other levels of limb loss. No differences were found between different prosthetic components. Reference ranges were established for U.S. SMs with and without various levels of limb loss, and the 6MWT was able to identify functional differences between groups. C1 [Linberg, Alison A.] Walter Reed Army Med Ctr, Mil Adv Training Ctr, Washington, DC 20307 USA. [Roach, Kathryn E.; Raya, Michele A.; Gailey, Robert S.] Univ Miami, Miller Sch Med, Dept Phys Therapy, Coral Gables, FL 33146 USA. [Campbell, Stuart M.] Brooke Army Med Ctr, Ctr Intrepid, San Antonio, TX USA. [Stoneman, Paul D.] Walter Reed Army Med Ctr, Washington, DC 20307 USA. [Gaunaurd, Ignacio A.; Gomez-Orozco, Carlos; Gailey, Robert S.] Miami Dept Vet Affairs Healthcare Syst, Miami, FL USA. RP Gailey, RS (reprint author), Univ Miami, Miller Sch Med, Dept Phys Therapy, 5915 Ponce de Leon Blvd,Plummer Bldg 5th Floor, Coral Gables, FL 33146 USA. EM rgailey@miami.edu OI Campbell, Stephen/0000-0002-2328-4136 FU Military Amputee Research Program; Telemedicine and Advanced Technology Research Center [W81XWH-06-2-0073]; U.S. Army Medical Research Acquisition Activity, Fort Detrick, Maryland FX This material was based on work supported by the Military Amputee Research Program and the Telemedicine and Advanced Technology Research Center (Prime Award No. W81XWH-06-2-0073). The U.S. Army Medical Research Acquisition Activity, Fort Detrick, Maryland, is the awarding and administering acquisition office. It was administered by the Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, and the South Florida Veterans Affairs Foundation for Research and Education, Inc. NR 36 TC 6 Z9 6 U1 1 U2 2 PU JOURNAL REHAB RES & DEV PI BALTIMORE PA DEPT OF VETERANS AFFAIRS REHABIL RES & DEVELOP CTR 103 SOUTH GAY STREET, BALTIMORE, MD 21202-4051 USA SN 0748-7711 EI 1938-1352 J9 J REHABIL RES DEV JI J. Rehabil. Res. Dev. PY 2013 VL 50 IS 7 BP 931 EP 939 DI 10.1682/JRRD.2012.05.0098 PG 9 WC Rehabilitation SC Rehabilitation GA 257VM UT WOS:000327415900009 PM 24301430 ER PT J AU Raya, MA Gailey, RS Gaunaurd, IA Jayne, DM Campbell, SM Gagne, E Manrique, PG Muller, DG Tucker, C AF Raya, Michele A. Gailey, Robert S. Gaunaurd, Ignacio A. Jayne, Daniel M. Campbell, Stuart M. Gagne, Erica Manrique, Patrick G. Muller, Daniel G. Tucker, Christen TI Comparison of three agility tests with male servicemembers: Edgren Side Step Test, T-Test, and Illinois Agility Test SO JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT LA English DT Article DE agility; Edgren Side Step Test; Illinois Agility Test; military; minimal detectable change; reliability; servicemembers; standard error of measurement; T-Test; validity ID PHYSIOLOGICAL-CHARACTERISTICS; TALENT IDENTIFICATION; SKATING PERFORMANCE; DIRECTION SPEED; PLAYERS; RELIABILITY; WOMEN; TEAM; BASKETBALL; VALIDITY AB Performance-based outcomes such as the T-Test, Edgren Side Step Test (ESST), and Illinois Agility Test (IAT) have been used to assess agility in athletes and nonathletes; however, the reliability and validity of these tests have not been established. The purpose of this study was to establish the reliability and convergent construct validity of the ESST, T-Test, and IAT in young, nondisabled, physically active male servicemembers (SMs). Ninety-seven male Active Duty U.S. Army SMs completed the study. Statistically significant differences were not found between the ESST (p = 0.10), T-Test (p = 0.09), and IAT (p = 0.23) when administered twice within a 24 to 48 h period. These tests were found to have excellent interrater reliability and moderate to good test-retest reliability. A good positive relationship exists between the IAT and T-Test (r = 0.76, p < 0.001) and a moderate negative relationship exists between the ESST and both the T-Test (r = -0.69, p < 0.001) and IAT (r = -0.65, p < 0.001). The results suggest that these tests are valid measures of agility that uniquely assess movement in different planes, thus providing a comprehensive assessment of high-level mobility. C1 [Raya, Michele A.; Gailey, Robert S.; Gagne, Erica; Manrique, Patrick G.; Muller, Daniel G.; Tucker, Christen] Univ Miami, Miller Sch Med, Dept Phys Therapy, Coral Gables, FL 33146 USA. [Gailey, Robert S.; Gaunaurd, Ignacio A.] Miami Dept Vet Affairs Healthcare Syst, Miami, FL USA. [Jayne, Daniel M.] Womack Army Med Ctr, Ft Bragg, NC USA. [Campbell, Stuart M.] Brooke Army Med Ctr, Ctr Intrepid, San Antonio, TX USA. RP Gailey, RS (reprint author), Univ Miami, Miller Sch Med, Dept Phys Therapy, 5915 Ponce de Leon Blvd,Plummer Bldg,5th Floor, Coral Gables, FL 33146 USA. EM rgailey@miami.edu OI Campbell, Stephen/0000-0002-2328-4136 FU Military Amputee Research Program; Telemedicine and Advanced Technology Research Center [W81XWH-06-2-0073]; U.S. Army Medical Research Acquisition Activity FX This material was based on work supported by the Military Amputee Research Program and Telemedicine and Advanced Technology Research Center (Prime Award No. W81XWH-06-2-0073). The U.S. Army Medical Research Acquisition Activity is the awarding and administering acquisition office. It was administered by the Henry M. Jackson Foundation for the Advancement of Military Medicine and the South Florida Veterans Affairs Foundation for Research and Education. NR 34 TC 8 Z9 8 U1 1 U2 18 PU JOURNAL REHAB RES & DEV PI BALTIMORE PA DEPT OF VETERANS AFFAIRS REHABIL RES & DEVELOP CTR 103 SOUTH GAY STREET, BALTIMORE, MD 21202-4051 USA SN 0748-7711 EI 1938-1352 J9 J REHABIL RES DEV JI J. Rehabil. Res. Dev. PY 2013 VL 50 IS 7 BP 951 EP 960 DI 10.1682/JRRD.2012.05.0096 PG 10 WC Rehabilitation SC Rehabilitation GA 257VM UT WOS:000327415900011 PM 24301432 ER PT J AU Gaunaurd, IA Roach, KE Raya, MA Hooper, R Linberg, AA Laferrier, JZ Campbell, SM Scoville, C Gailey, RS AF Gaunaurd, Ignacio A. Roach, Kathryn E. Raya, Michele A. Hooper, Rebecca Linberg, Alison A. Laferrier, Justin Z. Campbell, Stuart M. Scoville, Charles Gailey, Robert S. TI Factors related to high-level mobility in male servicemembers with traumatic lower-limb loss SO JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT LA English DT Article DE CHAMP; gait; high-level mobility; injury severity; lower-limb loss; prosthetics; rehabilitation; servicemembers; traumatic amputation; waist circumference ID INJURY SEVERITY SCORE; BIOMECHANICAL ANALYSIS; TRANSFEMORAL AMPUTEES; ENERGY-EXPENDITURE; IMPROVES ACCURACY; GAIT; AMPUTATION; WALKING; INDIVIDUALS; PROSTHESES AB The purpose of this study was to examine the possible relationship between factors modifiable by rehabilitation interventions (rehabilitation factors), other factors related to lower-limb loss (other factors), and high-level mobility as measured by the Comprehensive High-Level Activity Mobility Predictor (CHAMP) in servicemembers (SMs) with traumatic lower-limb loss. One-hundred eighteen male SMs with either unilateral transtibial amputation (TTA), unilateral transfemoral amputation (TFA), or bilateral lower-limb amputation (BLLA) participated. Stepwise regression analysis was used to develop separate regression models of factors predicting CHAMP score. Regression models containing both rehabilitation factors and other factors explained 81% (TTA), 36% (TFA), and 91% (BLLA) of the variance in CHAMP score. Rehabilitation factors such as lower-limb strength and dynamic balance were found to be significantly related to CHAMP score and can be enhanced with the appropriate intervention. Further, the findings support the importance of salvaging the knee joint and its effect on high-level mobility capabilities. Lastly, the J-shaped energy storage and return feet were found to improve high-level mobility for SMs with TTA. These results could help guide rehabilitation and aid in developing appropriate interventions to assist in maximizing high-level mobility capabilities for SMs with traumatic lower-limb loss. C1 [Gaunaurd, Ignacio A.; Gailey, Robert S.] Miami Dept Vet Affairs Healthcare Syst, Funct Outcomes Res & Evaluat Ctr, Miami, FL 33125 USA. [Gaunaurd, Ignacio A.; Roach, Kathryn E.; Raya, Michele A.; Gailey, Robert S.] Univ Miami, Miller Sch Med, Dept Phys Therapy, Coral Gables, FL 33124 USA. [Hooper, Rebecca; Campbell, Stuart M.] Brooke Army Med Ctr, Ctr Intrepid, San Antonio, TX USA. [Linberg, Alison A.; Scoville, Charles] Walter Reed Army Med Ctr, Mil Adv Training Ctr, Washington, DC 20307 USA. [Laferrier, Justin Z.] Univ Connecticut, Dept Kinesiol, Phys Therapy Program, Storrs, CT USA. RP Gaunaurd, IA (reprint author), Miami Dept Vet Affairs Healthcare Syst, 1201 NW 16th St, Miami, FL 33125 USA. EM ignacio.gaunaurd@va.gov OI Campbell, Stephen/0000-0002-2328-4136 FU Military Amputee Research Program; Telemedicine and Advanced Technology Research Center [W81XWH-06-2-0073]; U.S. Army Medical Research Acquisition Activity, Fort Detrick, Maryland FX This material was based on work supported by the Military Amputee Research Program and the Telemedicine and Advanced Technology Research Center (Prime Award No. W81XWH-06-2-0073). The U.S. Army Medical Research Acquisition Activity, Fort Detrick, Maryland, is the awarding and administering acquisition office. It was administered by the Henry M. Jackson Foundation for the Advancement of Military Medicine Inc and the South Florida Department of Veterans Affairs (VA) Foundation for Research and Education Inc. NR 61 TC 2 Z9 2 U1 4 U2 18 PU JOURNAL REHAB RES & DEV PI BALTIMORE PA DEPT OF VETERANS AFFAIRS REHABIL RES & DEVELOP CTR 103 SOUTH GAY STREET, BALTIMORE, MD 21202-4051 USA SN 0748-7711 EI 1938-1352 J9 J REHABIL RES DEV JI J. Rehabil. Res. Dev. PY 2013 VL 50 IS 7 BP 969 EP 983 DI 10.1682/JRRD.2013.02.0035 PG 15 WC Rehabilitation SC Rehabilitation GA 257VM UT WOS:000327415900013 PM 24301434 ER PT J AU Lynch, LN Chehovits, JG Luders, DG Belangie, M AF Lynch, Larry N. Chehovits, James G. Luders, David G. Belangie, Michael TI Joint Resealing Project at Fairchild Air Force Base, Washington Twenty-One-Year Field Performance SO TRANSPORTATION RESEARCH RECORD LA English DT Article AB In 1989, the U.S. Army Engineer Research and Development Center and Crafco, Inc., initiated a research effort to develop improved materials and processes for sealing joints in portland cement concrete pavements. Objectives were to develop specifications for improved hot-applied, jet fuel resistant (JFR) and non jet fuel resistant (non-OR) sealants and to determine the impact of installation configuration on field performance. The laboratory phase identified desired sealant properties, evaluated sealants for those properties, and developed sealants with improved low-temperature and aging properties. The field phase was installed in June 1991 at Fairchild Air Force Base, Washington, to determine performance of developed sealants compared with standard sealants and to determine whether performance could be improved by changing installation geometry. Thirteen sealants were installed. The field study documented installation and evaluations at 6 and 12 months. After study completion, the installations were monitored several additional times. Detailed papers were prepared after Sand 10 years. At 10 years, some sealants had greater than a 10-year life. In 2011, the installations reached 20 years of age. The JFR sections had been replaced, and non-JFR sections were still intact and were evaluated in April 2012. Results of the 21-year evaluation are presented. One silicone sealant and the improved non-JFR sealant achieved a 21-year life. Results also show that the flush-fill installation geometry increased life of the hot-applied asphalt sealants by more than 50% compared with the standard recessed configuration and should be considered for joint sealant installations. C1 [Lynch, Larry N.] US Army, Engn Res & Dev Ctr, Geotech & Struct Lab, Vicksburg, MS 39180 USA. [Chehovits, James G.] Crafco Inc, Chandler, AZ 85226 USA. [Luders, David G.] Fair Child AFB, Programs Dev Element, Washington, WA 99011 USA. RP Chehovits, JG (reprint author), Crafco Inc, 420 North Roosevelt Ave, Chandler, AZ 85226 USA. EM jim.chehovits@crafco.com FU U.S. Army Engineer Research and Development Center; Crafco, Inc. FX The authors acknowledge the support of the U.S. Army Engineer Research and Development Center and Crafco, Inc., in collecting and preparing the data for this article. The support of the following members of the Civil Engineering Squadron, Fairchild Air Force Base, during project installation and subsequent evaluations is greatly appreciated and acknowledged: Ron Sanders, Ted Strom, and David Luders. NR 6 TC 0 Z9 0 U1 1 U2 3 PU NATL ACAD SCIENCES PI WASHINGTON PA 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA SN 0361-1981 EI 2169-4052 J9 TRANSPORT RES REC JI Transp. Res. Record PY 2013 IS 2361 BP 98 EP 105 DI 10.3141/2361-12 PG 8 WC Engineering, Civil; Transportation; Transportation Science & Technology SC Engineering; Transportation GA 264ZT UT WOS:000327920200013 ER PT J AU Baideme, M Brady, A Robbins, C AF Baideme, Matthew Brady, Adam Robbins, Cristian TI Distributed Treatment Systems SO WATER ENVIRONMENT RESEARCH LA English DT Article DE onsite treatment; septic tank; decentralized treatment; distributed treatment; clustered systems ID WASTE-WATER TREATMENT; FIELD-SCALE EXPERIMENT; ON-SITE; AGRICULTURAL CATCHMENT; CONSTRUCTED WETLANDS; TECHNOLOGIES; MANAGEMENT; DISPOSAL; REMOVAL; FILTERS AB This section presents a review of the literature published in 2012 on topics relating to distributed treatment systems. This review is divided into the following sections: conventional systems; natural systems; onsite treatment applications for greywater reuse; and planning and treatment system management. C1 [Baideme, Matthew; Brady, Adam; Robbins, Cristian] US Mil Acad, Dept Geog & Environm Engn, West Point, NY 10996 USA. RP Baideme, M (reprint author), US Mil Acad, Dept Geog & Environm Engn, 745 Brewerton Rd, West Point, NY 10996 USA. EM matthew.baideme@usma.edu NR 54 TC 0 Z9 0 U1 0 U2 3 PU WATER ENVIRONMENT FEDERATION PI ALEXANDRIA PA 601 WYTHE ST, ALEXANDRIA, VA 22314-1994 USA SN 1061-4303 EI 1554-7531 J9 WATER ENVIRON RES JI Water Environ. Res. PY 2013 VL 85 IS 10 BP 1339 EP 1353 DI 10.2175/106143013X13698672322264 PG 15 WC Engineering, Environmental; Environmental Sciences; Limnology; Water Resources SC Engineering; Environmental Sciences & Ecology; Marine & Freshwater Biology; Water Resources GA 264FZ UT WOS:000327863700016 ER PT B AU Apo, DJ Sanghadasa, M Priya, S AF Apo, Daniel J. Sanghadasa, Mohan Priya, Shashank GP IEEE TI Low Frequency Arc-Based MEMS Structures for Vibration Energy Harvesting SO 2013 8TH ANNUAL IEEE INTERNATIONAL CONFERENCE ON NANO/MICRO ENGINEERED AND MOLECULAR SYSTEMS (IEEE NEMS 2013) LA English DT Proceedings Paper CT 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) CY APR 07-10, 2013 CL Suzhou, PEOPLES R CHINA SP IEEE Elect & Elect Engineers, IEEE Nanotechnol Council, Sci & Technol Micro Nanofabricat Lab, Peking Univ, Soochow Univ, Sci & Technol Microsystem Lab, Chinese Acad Sci, Shanghai Inst Microsystem & Informat Technol, Chinese Acad Sci, Suzhou Inst Nano Tech & Nano Bion, Univ Calif, Los Angeles, Chinese Int NEMS Soc, Natl Nat Sci Fdn China, City Univ Hongkong, Nanopolis Suzhou, CHINANO, Suzhou Ind Park, MEMS Journal Inc DE MEMS; microdevice; energy harvesting; circular arcs; multilayer AB This study reports the novel arc-based cantilevers for reducing the natural frequency of MEMS cantilever beams without the addition of tip/point mass. The results show an increased potential for energy extraction from naturally occurring vibration sources. An analytical model was used to model the effective mechanical properties of multilayered MEMS cantilevers while the natural frequencies were obtained by applying a finite element code. Results were obtained for two geometries of arc-based cantilevers as well as their linear counterparts. These results demonstrate that arc-based cantilevers vibrate at frequencies significantly lower than their linear components (up to 40% reduction in natural frequency). C1 [Apo, Daniel J.; Priya, Shashank] Virginia Tech, CEHMS, Blacksburg, VA 24061 USA. [Sanghadasa, Mohan] US Army RDECOM, Dev & Engn Ctr, Aviat & Missile Res, Redstone Arsenal, AL USA. RP Apo, DJ (reprint author), Virginia Tech, CEHMS, Blacksburg, VA 24061 USA. EM djapo@vt.edu FU National Science Foundation (NSF) through INAMM FX The authors acknowledge the financial support from the National Science Foundation (NSF) through INAMM program (S.P.) and through the CEHMS seed project. NR 5 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-6352-5; 978-1-4673-6351-8 PY 2013 BP 615 EP 618 PG 4 WC Engineering, Biomedical; Engineering, Electrical & Electronic; Nanoscience & Nanotechnology SC Engineering; Science & Technology - Other Topics GA BIA90 UT WOS:000327183000128 ER PT S AU George, J AF George, Jemin GP IEEE TI Robust Kalman Filtering for Discrete-Time Uncertain Stochastic Systems SO 2013 AMERICAN CONTROL CONFERENCE (ACC) SE Proceedings of the American Control Conference LA English DT Proceedings Paper CT American Control Conference (ACC) CY JUN 17-19, 2013 CL Washington, DC SP Boeing, Eaton, Halliburton, Honeywell, MathWorks, Mitsubishi Elect Res Lab, Natl Instruments, United Technologies Res Ctr, Xerox, dSpace, Journal Franklin Inst, GE Global Res, Quanser, SIAM, Springer, Taylor & Francis Grp CRC Press, Wiley ID LINEAR-SYSTEMS; STATE ESTIMATION; DESIGN AB Development of a robust Kalman filter for uncertain stochastic systems under persistent excitation and unknown measurement model is presented. The given discrete-time stochastic formulation does not require the knowledge of any bounds on parametric uncertainties and excitations. When there are no system uncertainties, the performance of the proposed robust estimator is similar to that of the traditional Kalman filter and the proposed approach asymptotically recovers the desired optimal performance in the presence of uncertainties and/or persistent excitation. C1 US Army Res Lab, Adelphi, MD 20783 USA. RP George, J (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. EM jemin.george.civ@mail.mil NR 29 TC 0 Z9 0 U1 0 U2 3 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 0743-1619 BN 978-1-4799-0178-4 J9 P AMER CONTR CONF PY 2013 BP 2466 EP 2471 PG 6 WC Automation & Control Systems; Engineering, Electrical & Electronic SC Automation & Control Systems; Engineering GA BIB32 UT WOS:000327210202104 ER PT S AU George, J AF George, Jemin GP IEEE TI An LMI-based Robust Fault Detection and Isolation Scheme SO 2013 AMERICAN CONTROL CONFERENCE (ACC) SE Proceedings of the American Control Conference LA English DT Proceedings Paper CT American Control Conference (ACC) CY JUN 17-19, 2013 CL Washington, DC SP Boeing, Eaton, Halliburton, Honeywell, MathWorks, Mitsubishi Elect Res Lab, Natl Instruments, United Technologies Res Ctr, Xerox, dSpace, Journal Franklin Inst, GE Global Res, Quanser, SIAM, Springer, Taylor & Francis Grp CRC Press, Wiley ID DETECTION FILTER; SYSTEMS AB This paper presents a linear matrix inequality (LMI)-based robust fault detection and isolation scheme that can precisely detect/isolate simultaneously occurring actuator and sensor faults within uncertain linear stochastic systems. This robust fault detection scheme would be able to distinguish between model uncertainties and actuator failures, therefore eliminating the problem of false alarms even in the presence of matched uncertainties. The proposed approach can also be used for sensor fault identification and the reconstruction of true outputs from faulty sensor outputs. Simulation results presented here validate the effectiveness of the proposed robust fault detection and isolation system. C1 US Army, Res Lab, Adelphi, MD 20783 USA. RP George, J (reprint author), US Army, Res Lab, Adelphi, MD 20783 USA. EM jemin.george.civ@mail.mil NR 23 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 0743-1619 BN 978-1-4799-0178-4 J9 P AMER CONTR CONF PY 2013 BP 2784 EP 2789 PG 6 WC Automation & Control Systems; Engineering, Electrical & Electronic SC Automation & Control Systems; Engineering GA BIB32 UT WOS:000327210202156 ER PT B AU Zhong, C Kirubakaran, DS Yen, J Liu, P Hutchinson, S Cam, H AF Zhong, Chen Kirubakaran, Deepak S. Yen, John Liu, Peng Hutchinson, Steve Cam, Hasan BE Glass, K Colbaugh, R Sanfillippo, A Kao, A Gabbay, M Corley, C Li, J Khan, L Wynne, A Coote, L Mao, W Zeng, D Yaghoobi, A TI How to Use Experience in Cyber Analysis: An Analytical Reasoning Support System SO 2013 IEEE INTERNATIONAL CONFERENCE ON INTELLIGENCE AND SECURITY INFORMATICS: BIG DATA, EMERGENT THREATS, AND DECISION-MAKING IN SECURITY INFORMATICS LA English DT Proceedings Paper CT 11th IEEE International Conference on Intelligence and Security Informatics (IEEE ISI) CY JUN 04-07, 2013 CL Pacific NW Natl Lab, Seattle, WA SP IEEE, IEEE Intelligent Transportat Syst Soc, Intelligence Adv Res Projects Act HO Pacific NW Natl Lab DE Experience-aided; Analytical Reasoning AB Cyber analysis is a difficult task for analysts due to huge amounts of noise-abundant monitoring data and increasing complexity of the reasoning tasks. Therefore, experience from experts can provide guidance for analysts' analytical reasoning and contribute to training. Despite its great potential benefits, experience has not been effectively leveraged in the existing reasoning support systems due to the difficulty of elicitation and reuse. To fill the gap, we propose an experience-aided reasoning support system which can automatically capture experts' experience and subsequently guide the novices' reasoning in a step-by-step manner. Drawing on cognitive theory, we model experience as a reasoning process involving "actions", "observations", and "hypotheses". Computability and adaptability are the comparative advantages of this model: the "hypotheses" capture analysts' internal mental reasoning as a black box, while the "actions" and "observations" formally representing the external context and analysts' evidence exploration activities. This paper demonstrates how this system, built on this experience model, can capture and utilize experience effectively. C1 [Zhong, Chen; Kirubakaran, Deepak S.; Yen, John; Liu, Peng] Penn State Univ, State Coll, PA 16803 USA. [Hutchinson, Steve; Cam, Hasan] US Army Res Lab, Adelphi, MD 20783 USA. RP Zhong, C (reprint author), Penn State Univ, State Coll, PA 16803 USA. EM czz111@ist.psu.edu; dok5181@ist.psu.edu; jyen@ist.psu.edu; pliu@ist.psu.edu; Steve.E.Hutchinson.ctr@mail.mil; hasan.cam.civ@mail.mil FU ARO [W911NF-09-1-0525] FX Supported by ARO Grant W911NF-09-1-0525 (MURI). NR 7 TC 2 Z9 2 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-6213-9; 978-1-4673-6214-6 PY 2013 BP 263 EP 265 PG 3 WC Computer Science, Theory & Methods; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BHY71 UT WOS:000327025200060 ER PT J AU Kawamura, K Severinghaus, JP Albert, MR Courville, ZR Fahnestock, MA Scambos, T Shields, E Shuman, CA AF Kawamura, K. Severinghaus, J. P. Albert, M. R. Courville, Z. R. Fahnestock, M. A. Scambos, T. Shields, E. Shuman, C. A. TI Kinetic fractionation of gases by deep air convection in polar firn SO ATMOSPHERIC CHEMISTRY AND PHYSICS LA English DT Article ID ABRUPT CLIMATE-CHANGE; THERMAL-DIFFUSION CONSTANTS; EAST ANTARCTIC PLATEAU; ICE CORE; ATMOSPHERIC CO2; TEMPERATURE; GREENLAND; TRANSPORT; MODEL; SNOW AB A previously unrecognized type of gas fractionation occurs in firn air columns subjected to intense convection. It is a form of kinetic fractionation that depends on the fact that different gases have different molecular diffusivities. Convective mixing continually disturbs diffusive equilibrium, and gases diffuse back toward diffusive equilibrium under the influence of gravity and thermal gradients. In near-surface firn where convection and diffusion compete as gas transport mechanisms, slow-diffusing gases such as krypton (Kr) and xenon (Xe) are more heavily impacted by convection than fast diffusing gases such as nitrogen (N-2) and argon (Ar), and the signals are preserved in deep firn and ice. We show a simple theory that predicts this kinetic effect, and the theory is confirmed by observations using a newly-developed Kr and Xe stable isotope system in air samples from the Megadunes field site on the East Antarctic plateau. Numerical simulations confirm the effect's magnitude at this site. A main purpose of this work is to support the development of a proxy indicator of past convection in firn, for use in ice-core gas records. To this aim, we also show with the simulations that the magnitude of the kinetic effect is fairly insensitive to the exact profile of convective strength, if the overall thickness of the convective zone is kept constant. These results suggest that it may be feasible to test for the existence of an extremely deep (similar to 30-40 m) convective zone, which has been hypothesized for glacial maxima, by future ice-core measurements. C1 [Kawamura, K.] Natl Inst Polar Res, Tachikawa, Tokyo, Japan. [Kawamura, K.] Japan Agcy Marine Earth Sci & Technol, Inst Biogeosci, Yokosuka, Kanagawa 2370061, Japan. [Severinghaus, J. P.; Shields, E.] Univ Calif San Diego, Scripps Inst Oceanog, San Diego, CA 92103 USA. [Albert, M. R.; Courville, Z. R.] Dartmouth Coll, Thayer Sch Engn, Hanover, NH 03755 USA. [Albert, M. R.; Courville, Z. R.] US Army, Cold Reg Res & Engn Lab, Cryospher & Terr Sci Div, Hanover, NH 03755 USA. [Fahnestock, M. A.] Univ Alaska Fairbanks, Inst Geophys, Fairbanks, AK 99775 USA. [Scambos, T.] Natl Snow & Ice Data Ctr, Boulder, CO USA. [Shuman, C. A.] NASA, Goddard Space Flight Ctr, Cryospher Sci Branch, Greenbelt, MD 20771 USA. RP Kawamura, K (reprint author), Natl Inst Polar Res, Tachikawa, Tokyo, Japan. EM kawamura@nipr.ac.jp RI Fahnestock, Mark/N-2678-2013; OI Kawamura, Kenji/0000-0003-1163-700X FU NSF-OPP [02-30452]; Gary Comer Abrupt Climate Change Fellowship; JSPS KAKENHI [21671001]; NIPR publication subsidy FX Michael Bender made the nitrogen isotope measurements. Helpful discussions with Ralph Keeling, Bruce Cornuelle, and Bill Young improved the manuscript. We thank the Megadunes Field Team and NY Air National Guard for field support, and the Light Ground Traverse 2003-2004 for preparing the skiway that enabled LC-130 landings at the Megadunes site. Louise Albershardt of Ice Drilling and Design Operations group (IDDO) did the drilling. K. Kawamura acknowledges Fuyuki Saito of JAM-STEC and Jun'ichi Okuno of NIPR for assisting LaTeX editing. Support for this work came from NSF-OPP 02-30452 (J. P. Severinghaus), Gary Comer Abrupt Climate Change Fellowship (for supporting K. Kawamura as a postdoc at SIO) and JSPS KAKENHI 21671001 (K. Kawamura). The production of the paper was supported by an NIPR publication subsidy. NR 43 TC 3 Z9 3 U1 2 U2 20 PU COPERNICUS GESELLSCHAFT MBH PI GOTTINGEN PA BAHNHOFSALLEE 1E, GOTTINGEN, 37081, GERMANY SN 1680-7316 EI 1680-7324 J9 ATMOS CHEM PHYS JI Atmos. Chem. Phys. PY 2013 VL 13 IS 21 BP 11141 EP 11155 DI 10.5194/acp-13-11141-2013 PG 15 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA 253PP UT WOS:000327101900037 ER PT J AU Domvri, K Zarogoulidis, P Darwiche, K Browning, RF Li, Q Turner, JF Kioumis, I Spyratos, D Porpodis, K Papaiwannou, A Tsiouda, T Freitag, L Zarogoulidis, K AF Domvri, Kalliopi Zarogoulidis, Paul Darwiche, Kaid Browning, Robert F. Li, Qiang Turner, J. Francis Kioumis, Ioannis Spyratos, Dionysios Porpodis, Konstantinos Papaiwannou, Antonis Tsiouda, Theodora Freitag, Lutz Zarogoulidis, Konstantinos TI Molecular Targeted Drugs and Biomarkers in NSCLC, the Evolving Role of Individualized Therapy SO JOURNAL OF CANCER LA English DT Review DE NSCLC; pathways; targeted treatment; maintenance ID CELL-LUNG-CANCER; GROWTH-FACTOR-RECEPTOR; RANDOMIZED PHASE-II; CHEMOTHERAPY-NAIVE PATIENTS; PREVIOUSLY TREATED PATIENTS; QUALITY-OF-LIFE; K-RAS MUTATIONS; CLINICALLY SELECTED PATIENTS; TYROSINE KINASE INHIBITORS; COMPREHENSIVE GERIATRIC ASSESSMENT AB Lung cancer first line treatment has been directed from the non-specific cytotoxic doublet chemotherapy to the molecular targeted. The major limitation of the targeted therapies still remains the small number of patients positive to gene mutations. Furthermore, the differentiation between second line and maintenance therapy has not been fully clarified and differs in the clinical practice between cancer centers. The authors present a segregation between maintenance treatment and second line and present a possible definition for the term "maintenance" treatment. In addition, cancer cell evolution induces mutations and therefore either targeted therapies or non-specific chemotherapy drugs in many patients become ineffective. In the present work pathways such as epidermal growth factor, anaplastic lymphoma kinase, met proto-oncogene and PI3K are extensively presented and correlated with current chemotherapy treatment. Future, perspectives for targeted treatment are presented based on the current publications and ongoing clinical trials. C1 [Domvri, Kalliopi; Zarogoulidis, Paul; Kioumis, Ioannis; Spyratos, Dionysios; Porpodis, Konstantinos; Papaiwannou, Antonis; Zarogoulidis, Konstantinos] Aristotle Univ Thessaloniki, Dept Pulm, Oncol Unit, G Papanikolaou Gen Hosp, GR-54006 Thessaloniki, Greece. [Zarogoulidis, Paul; Darwiche, Kaid; Freitag, Lutz] Univ Duisburg Essen, Univ Hosp, West German Lung Ctr, Dept Intervent Pneumol,Ruhrlandklin, Essen, Germany. [Browning, Robert F.] Walter Reed Army Med Ctr, Natl Naval Med Ctr, Bethesda, MD USA. [Li, Qiang] Second Mil Med Univ, Affiliated Hosp 1, Changhai Hosp, Dept Resp Dis, Shanghai, Peoples R China. [Turner, J. Francis] Univ Nevada, Natl Supercomp Ctr Energy & Environm, Sch Med, Las Vegas, NV 89154 USA. [Tsiouda, Theodora] Theiageneio Anticanc Hosp, Internal Med Unit, Thessaloniki, Greece. RP Zarogoulidis, P (reprint author), Aristotle Univ Thessaloniki, Dept Pulm, Oncol Unit, G Papanikolaou Gen Hosp, GR-54006 Thessaloniki, Greece. EM kzarogoy@auth.gr NR 219 TC 21 Z9 21 U1 0 U2 7 PU IVYSPRING INT PUBL PI LAKE HAVEN PA PO BOX 4546, LAKE HAVEN, NSW 2263, AUSTRALIA SN 1837-9664 J9 J CANCER JI J. Cancer PY 2013 VL 4 IS 9 BP 736 EP 754 DI 10.7150/jca.7734 PG 19 WC Oncology SC Oncology GA 260HU UT WOS:000327586400006 PM 24312144 ER PT J AU Han, SD Borodin, O Allen, JL Seo, DM McOwen, DW Yun, SH Henderson, WA AF Han, Sang-Don Borodin, Oleg Allen, Joshua L. Seo, Daniel M. McOwen, Dennis W. Yun, Sung-Hyun Henderson, Wesley A. TI Electrolyte Solvation and Ionic Association IV. Acetonitrile-Lithium Difluoro(oxalato)borate (LiDFOB) Mixtures SO JOURNAL OF THE ELECTROCHEMICAL SOCIETY LA English DT Article ID MOLECULAR-DYNAMICS SIMULATIONS; FREE GRAPHITE-ELECTRODES; PHASE-TRANSITION; ELECTROCHEMICAL PROPERTIES; ALPHA-ACETONITRILE; POWDER DIFFRACTION; THERMAL-STABILITY; CRYSTAL-STRUCTURE; BATTERIES; SALT AB A methodology is demonstrated for the rapid evaluation of the bulk electrolyte characteristics of the salt lithium difluoro(oxalato)borate (LiDFOB) (or lithium oxalyldifluoroborate (LiODFB)). Acetonitrile (AN) has been used as a model solvent. Utilizing information from a combination of methods-i.e., the determination of the (AN)(n)-LiDFOB thermal phase behavior (phase diagram and the corresponding solvate crystal structures), a Raman spectroscopic evaluation of the solvation/ionic association interactions and molecular dynamics (MD) simulations-detailed insight into the coordination interactions of the DFOB- anion is obtained and explanations are readily available for the solution behavior and variability in the transport properties (viscosity and ionic conductivity) of AN solutions with this salt relative to other lithium salts. (C) 2013 The Electrochemical Society. All rights reserved. C1 [Han, Sang-Don; Allen, Joshua L.; Seo, Daniel M.; McOwen, Dennis W.; Yun, Sung-Hyun; Henderson, Wesley A.] N Carolina State Univ, Dept Chem & Biomol Engn, Ion Liquids & Electrolytes Energy Technol ILEET L, Raleigh, NC 27695 USA. [Borodin, Oleg] US Army Res Lab, Electrochem Branch, Adelphi, MD 20783 USA. [Yun, Sung-Hyun] Gwangju Inst Sci & Technol, Sch Environm Sci & Engn, Kwangju 500712, South Korea. RP Han, SD (reprint author), N Carolina State Univ, Dept Chem & Biomol Engn, Ion Liquids & Electrolytes Energy Technol ILEET L, Raleigh, NC 27695 USA. EM olegutah@gmail.com; whender@ncsu.edu RI Borodin, Oleg/B-6855-2012; McOwen, Dennis/N-3337-2014 OI Borodin, Oleg/0000-0002-9428-5291; McOwen, Dennis/0000-0002-1313-1574 FU U.S. Department of Energy Batteries for Advanced Transportation Technologies (BATT) Program [DE-AC02-05-CH11231] FX The authors wish to express their gratitude to the U.S. Department of Energy Batteries for Advanced Transportation Technologies (BATT) Program which fully supported the experimental research under Award Number DE-AC02-05-CH11231. NR 64 TC 12 Z9 12 U1 4 U2 44 PU ELECTROCHEMICAL SOC INC PI PENNINGTON PA 65 SOUTH MAIN STREET, PENNINGTON, NJ 08534 USA SN 0013-4651 EI 1945-7111 J9 J ELECTROCHEM SOC JI J. Electrochem. Soc. PY 2013 VL 160 IS 11 BP A2100 EP A2110 DI 10.1149/2.094309jes PG 11 WC Electrochemistry; Materials Science, Coatings & Films SC Electrochemistry; Materials Science GA 251CI UT WOS:000326905000022 ER PT J AU Li, SR Sinha, NN Chen, CH Xu, K Dahn, JR AF Li, S. R. Sinha, N. N. Chen, C. H. Xu, K. Dahn, J. R. TI A Consideration of Electrolyte Additives for LiNi0.5Mn1.5O4/Li4Ti5O12 Li-Ion Cells SO JOURNAL OF THE ELECTROCHEMICAL SOCIETY LA English DT Article ID NONAQUEOUS SOLVENTS; SPINEL OXIDES; BATTERIES AB LNMO/LTO cells represent an excellent vehicle with which to test the impact of electrolyte additives on cell performance due to the high potential of LNMO which leads to electrolyte oxidation. Additives that prevent this oxidation are desired. Electrolyte additive researchers normally compare the capacity retention versus cycle number of cells with and without additives. If the capacity retention is improved, the additive is "good". In this paper, this logic is shown to be flawed. One additive, LiO-t-C4F9, which does improve capacity retention versus cycle number, is shown to do so by increasing electrolyte oxidation at the positive electrode. This causes increased charge end point capacity slippage and increased self discharge rates. As such, these additives, like many promoted in the literature, are not "good", but are "bad". On the other hand, one additive, Al(HFiP)(3), is shown to reduce parasitic reactions at the LNMO electrode but does not lead to improved capacity retention. A full understanding of the impact of the additive on the parasitic reaction rates at both positive and negative electrodes is required before a sound judgment about the impact of an additive can be made. Therefore, additive researchers must pay attention to coulombic efficiency, capacity end point slippage, reversible and irreversible capacity loss during storage as well as voltage drop during storage in addition to the long-time cycling performance for cells to get an overall evaluation of electrolyte additives. (C) 2013 The Electrochemical Society. All rights reserved. C1 [Li, S. R.; Chen, C. H.] Univ Sci & Technol China, Dept Mat Sci & Engn, CAS Key Lab Mat Energy Convers, Hefei 230026, Anhui, Peoples R China. [Li, S. R.; Sinha, N. N.; Dahn, J. R.] Dalhousie Univ, Dept Phys & Atmospher Sci, Halifax, NS B3H 4R2, Canada. [Xu, K.] US Army, Electrochem Branch, Power & Energy Div, Sensor & Electron Devices Directorate,Res Lab, Adelphi, MD 20783 USA. RP Li, SR (reprint author), Univ Sci & Technol China, Dept Mat Sci & Engn, CAS Key Lab Mat Energy Convers, Hefei 230026, Anhui, Peoples R China. EM jeff.dahn@dal.ca RI Chen, Chunhua/F-5897-2010 FU 3M Canada; NSERC of the Industrial Research Chairs program; China Scholarship Council FX The authors acknowledge the support of this work by 3M Canada and NSERC under the auspices of the Industrial Research Chairs program. The authors would also like to thank the appropriate manufacturers for providing the electrodes for these tests. S. R. Li gratefully acknowledges the support of the China Scholarship Council. NR 18 TC 2 Z9 2 U1 4 U2 86 PU ELECTROCHEMICAL SOC INC PI PENNINGTON PA 65 SOUTH MAIN STREET, PENNINGTON, NJ 08534 USA SN 0013-4651 EI 1945-7111 J9 J ELECTROCHEM SOC JI J. Electrochem. Soc. PY 2013 VL 160 IS 11 BP A2014 EP A2020 DI 10.1149/2.048311jes PG 7 WC Electrochemistry; Materials Science, Coatings & Films SC Electrochemistry; Materials Science GA 251CI UT WOS:000326905000011 ER PT J AU Belanich, J Orvis, KL Sibley, DE AF Belanich, James Orvis, Kara L. Sibley, Daragh E. TI PC-Based Game Features That Influence Instruction and Learner Motivation SO MILITARY PSYCHOLOGY LA English DT Article DE training; computer game; Army; desktop simulation; instructional characteristics ID COGNITIVE INTEREST; SEDUCTIVE DETAILS; MULTIMEDIA; ENVIRONMENTS; ATTENTION; RETENTION; SCIENCE; MEMORY; MODES; TEXT AB PC-based games are currently being used for military training, but the instructional and motivational features of such technology are not well understood. To identify features of training games that influence instruction and motivation, a popular first-person-perspective game with a military theme was analyzed empirically. Twenty-one participants played the "basic training" portion of the game, which included Army background information, virtual marksmanship training, an obstacle course, virtual weapons familiarization, and an urban terrain training mission. The results of this research provide useful information to individuals developing training games, desktop simulations, and interactive multimedia course-ware to meet optimal training objectives and strategies. C1 [Belanich, James] US Army Res Inst Behav & Social Sci, Dept Army, Arlington, VA USA. [Orvis, Kara L.] US Army Res Inst Behav & Social Sci, Arlington, VA USA. [Sibley, Daragh E.] George Mason Univ, Fairfax, VA 22030 USA. RP Belanich, J (reprint author), Inst Def Anal, 4850 Mark Ctr Dr, Alexandria, VA 22311 USA. EM jbelanic@ida.org NR 47 TC 4 Z9 4 U1 3 U2 8 PU AMER PSYCHOLOGICAL ASSOC PI WASHINGTON PA 750 FIRST ST NE, WASHINGTON, DC 20002-4242 USA SN 0899-5605 EI 1532-7876 J9 MIL PSYCHOL JI Milit. Psychol. PY 2013 VL 25 IS 3 SI SI BP 206 EP 217 DI 10.1037/h0094963 PG 12 WC Psychology, Multidisciplinary SC Psychology GA 253BY UT WOS:000327058000004 ER PT J AU Johnston, JH Fiore, SM Paris, C Smith, CAP AF Johnston, Joan H. Fiore, Stephen M. Paris, Carol Smith, C. A. P. TI Application of Cognitive Load Theory to Develop a Measure of Team Cognitive Efficiency SO MILITARY PSYCHOLOGY LA English DT Article DE decision making; cognitive load; team cognition ID WORKING-MEMORY; INSTRUCTIONAL CONDITIONS; TRAINING ENVIRONMENTS; SPLIT-ATTENTION; DESIGN AB Improving human systems integration through technologically advanced training and performance aids has become increasingly important to military transformation. Measures of improved cognitive and coordination processes arising from the employment of transformational tools are necessary to guide the refinement and future development of such technologies. In this article, we describe a cognitive load theory approach to developing a combinatory measure of individual workload and team performance following an experimental intervention involving training and a decision support system. We discuss how indicators of what we term team cognitive efficiency can improve assessing the effectiveness of transformational processes and technologies. C1 [Johnston, Joan H.; Paris, Carol] Naval Air Warfare Ctr, Training Syst Div, Orlando, FL USA. [Fiore, Stephen M.] Univ Cent Florida, Dept Philosophy, Orlando, FL 32816 USA. [Fiore, Stephen M.] Univ Cent Florida, Inst Simulat & Training, Orlando, FL 32816 USA. [Smith, C. A. P.] Colorado State Univ, Ft Collins, CO 80523 USA. RP Johnston, JH (reprint author), US Army Res Inst, 12350 Res Pkwy, Orlando, FL 32826 USA. EM joan.johnston@us.army.mil OI Fiore, Stephen/0000-0003-3529-1322 NR 50 TC 4 Z9 4 U1 4 U2 9 PU AMER PSYCHOLOGICAL ASSOC PI WASHINGTON PA 750 FIRST ST NE, WASHINGTON, DC 20002-4242 USA SN 0899-5605 EI 1532-7876 J9 MIL PSYCHOL JI Milit. Psychol. PY 2013 VL 25 IS 3 SI SI BP 252 EP 265 DI 10.1037/h0094967 PG 14 WC Psychology, Multidisciplinary SC Psychology GA 253BY UT WOS:000327058000008 ER PT S AU Shukla, MK Hill, F Leszczynski, J AF Shukla, Manoj K. Hill, Frances Leszczynski, Jerzy BE Leszczynski, J Puzyn, T TI Interactions of Carbon Nanostructures and Small Gold Clusters with Nucleic Acid Bases and Watson-Crick Base Pairs and Nanocontacts Involving M-n-C-60-M-n (M = Au, Ag, and Pd; n = 2-8) System: Computational Elucidation of Structures and Characteristics SO TOWARDS EFFICIENT DESIGNING OF SAFE NANOMATERIALS: INNOVATIVE MERGE OF COMPUTATIONAL APPROACHES AND EXPERIMENTAL TECHNIQUES SE RSC Nanoscience and Nanotechnology LA English DT Article; Book Chapter ID DENSITY-FUNCTIONAL THEORY; DNA BASES; IONIZATION-POTENTIALS; THEORETICAL CHEMISTRY; ELECTRONIC-STRUCTURE; NONCOVALENT INTERACTIONS; RAMAN-SPECTROSCOPY; ALUMINUM-OXIDE; BASIS-SETS; GAS-PHASE C1 [Shukla, Manoj K.; Hill, Frances] US Army Engineer Res & Dev Ctr, Environm Lab, Vicksburg, MS USA. [Leszczynski, Jerzy] Jackson State Univ, Interdisplinary Ctr Nanotox, Dept Chem & Biochem, Jackson, MS USA. RP Shukla, MK (reprint author), US Army Engineer Res & Dev Ctr, Environm Lab, Vicksburg, MS USA. NR 149 TC 0 Z9 0 U1 0 U2 1 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, CAMBRIDGE CB4 4WF, CAMBS, ENGLAND SN 1757-7136 BN 978-1-84973-547-6; 978-1-84973-453-0 J9 RSC NANOSCI NANOTECH PY 2013 VL 25 BP 108 EP 147 D2 10.1039/9781849735476 PG 40 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Science & Technology - Other Topics; Materials Science GA BHW55 UT WOS:000326863100008 ER PT S AU Steevens, JA Bednar, A Chappell, M Donohue, K Ginsberg, M Guy, K Johnson, D Kennedy, A Moser, R Page, M Poda, A Weiss, C AF Steevens, J. A. Bednar, A. Chappell, M. Donohue, K. Ginsberg, M. Guy, K. Johnson, D. Kennedy, A. Moser, R. Page, M. Poda, A. Weiss, C., Jr. BE Leszczynski, J Puzyn, T TI Comprehensive Environmental Assessment of Nanotechnologies: a Case Study Using Self-decontaminating Surface Materials SO TOWARDS EFFICIENT DESIGNING OF SAFE NANOMATERIALS: INNOVATIVE MERGE OF COMPUTATIONAL APPROACHES AND EXPERIMENTAL TECHNIQUES SE RSC Nanoscience and Nanotechnology LA English DT Article; Book Chapter ID TITANIUM-DIOXIDE NANOPARTICLES; PHOTOCATALYTIC OXIDATION; AIR PURIFICATION; PARTICLE-SIZE; CELL-LINE; IN-VITRO; TIO2; TOXICITY; SKIN; PENETRATION C1 [Steevens, J. A.; Bednar, A.; Chappell, M.; Donohue, K.; Johnson, D.; Kennedy, A.; Moser, R.; Poda, A.; Weiss, C., Jr.] US Army ERDC, Vicksburg, MS 39180 USA. [Ginsberg, M.; Guy, K.; Page, M.] US Army ERDC, Champaign, IL 60822 USA. RP Steevens, JA (reprint author), US Army ERDC, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM Jeffery.A.Steevens@us.army.mil RI Poda, Aimee/K-1905-2012 NR 47 TC 0 Z9 0 U1 0 U2 1 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, CAMBRIDGE CB4 4WF, CAMBS, ENGLAND SN 1757-7136 BN 978-1-84973-547-6; 978-1-84973-453-0 J9 RSC NANOSCI NANOTECH PY 2013 VL 25 BP 314 EP 346 DI 10.1039/9781849735476-00314 D2 10.1039/9781849735476 PG 33 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Science & Technology - Other Topics; Materials Science GA BHW55 UT WOS:000326863100014 ER PT J AU Chhin, S Chumack, K Dahl, T David, ET Kurzeja, P Magruder, M Telewski, FW AF Chhin, Sophan Chumack, Katherine Dahl, Travis David, Eric T. Kurzeja, Phillip Magruder, Matthew Telewski, Frank W. TI GROWTH-CLIMATE RELATIONSHIPS OF PINUS STROBUS IN THE FLOODWAY VERSUS TERRACE FOREST ALONG THE BANKS OF THE RED CEDAR RIVER, MICHIGAN SO TREE-RING RESEARCH LA English DT Article DE climate; tree rings; dendrochronology; Pinta strobus; river hydrology; ecology ID BOTTOMLAND HARDWOOD FOREST; EASTERN WHITE-PINE; OLD-GROWTH; HYDROLOGICAL GRADIENT; ALLEGHENY PLATEAU; TREE GROWTH; HEMLOCK; IMPACTS; CONIFER; CANADA AB We examined the effects of climate (i.e. temperature, precipitation, moisture index, river discharge) on the radial growth of eastern white pine (Pious strobus) in two contrasting microhabitats (floodway versus terrace) in relation to an elevational and moisture gradient along the banks of the Red Cedar River, Michigan. We hypothesized that trees growing on the terrace sites would have a greater sensitivity to climatic factors than trees growing in the floodway. Increment cores were sampled and crossdated from dominant and co-dominant trees in the floodway and terrace sites and standardized growth chronologies were developed. Mean sensitivity, standard deviation, percentage of absent rings, and intertree correlation were generally greater for eastern white pine on the terrace compared to the floodway forests. Dendroclimatic relationships were examined with bootstrapped correlation analysis, which indicated that radial growth of eastern white pine in both floodway and terrace sites was negatively associated with summer temperature (i.e. June and July) of the current growing season. Radial growth in both floodway and terrace sites were positively related to current May precipitation, moisture index, and river discharge. Dendroclimatic response of eastern white pine in floodway and terrace sites differed in that the effect of summer moisture stress was more persistent in the terrace sites into later summer (i.e. current July) whereas floodway sites showed a negative response to prior-year May precipitation and moisture index. Although precipitation and hydrological conditions of the river were generally favorable during the summer months, which appeared to have promoted soil moisture recharge, flooding in early winter (i.e. prior November) had a negative impact on growth in both microhabitats. The effect of winter river discharge was significantly negative in January (t) in the floodway sites compared to the terrace sites. C1 [Chhin, Sophan; Chumack, Katherine; David, Eric T.; Magruder, Matthew] Michigan State Univ, Dept Forestry, E Lansing, MI 48824 USA. [Dahl, Travis] Michigan State Univ, Dept Geol, E Lansing, MI 48824 USA. [Dahl, Travis] US Army Corps Engineers, Detroit, MI 48226 USA. [Kurzeja, Phillip; Telewski, Frank W.] Michigan State Univ, Dept Plant Biol, E Lansing, MI 48824 USA. [Telewski, Frank W.] Michigan State Univ, WJ Beal Bot Garden, E Lansing, MI 48824 USA. [Telewski, Frank W.] Michigan State Univ, E Lansing, MI 48824 USA. RP Telewski, FW (reprint author), Michigan State Univ, Dept Plant Biol, Plant Biol Bldg,612 Wilson Rd,Room 166, E Lansing, MI 48824 USA. EM telewski@msu.edu RI Dahl, Travis/I-8591-2012; Telewski, Frank/I-6842-2016 OI Dahl, Travis/0000-0003-2422-3965; Telewski, Frank/0000-0001-7957-9841 NR 43 TC 3 Z9 3 U1 5 U2 30 PU TREE-RING SOC PI TUCSON PA UNIV ARIZONA, TREE-RING LABORATORY, BLDG 58, TUCSON, AZ 85721 USA SN 1536-1098 J9 TREE-RING RES JI Tree-Ring Res. PY 2013 VL 69 IS 2 BP 37 EP 47 DI 10.3959/1536-1098-69.2.37 PG 11 WC Forestry SC Forestry GA 247IL UT WOS:000326611000001 ER PT S AU Eaton, MJAN AF Eaton, Major Joshua A. N. GP IEEE TI Point of Impact: Delivering Mission Essential Supplies to the Warfighter through the Joint Precision Airdrop System SO 2013 7TH ANNUAL IEEE INTERNATIONAL SYSTEMS CONFERENCE (SYSCON 2013) SE Annual IEEE Systems Conference LA English DT Proceedings Paper CT 7th Annual IEEE International Systems Conference (SysCon) CY APR 15-18, 2013 CL Orlando, FL SP IEEE DE Joint Precision Airdrop System; Systems Engineering; Systems Architecture; Design Structure Matrix; Resupply; Complexity; Decomposition; Stakeholder Analysis; Function; Form AB Soldiers know firsthand the criticality of having mission essential supplies and equipment arrive at the right place, at the right time. This is of particular importance when operating in remote locations around the world where hostilities are prevalent, terrain is restrictive and mission accomplishment has strategic implications. The Joint Precision Airdrop System (JPADS) is a guided logistical resupply platform that delivers supplies and equipment in a precise manner to Soldiers operating in restrictive or hostile terrain from a high altitude when conventional means of resupply are unavailable, unrealistic or ill-advised. Our current force structure requires a system that can operate in a dynamic and mercurial environment in order to rapidly adjust to changes on the ground. The research paper will explore the JPADS from a Systems Architecture perspective in order to decompose the system and provide critical system details, which will aid in the Design Structure Matrix (DSM) analysis that will follow. The outcome of this research is to not only provide recommendations to the project sponsors working on the JPADS, but to illustrate the value of using Systems Engineering methodologies and tools to analyze complex systems and challenges. C1 US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA. RP Eaton, MJAN (reprint author), US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA. EM joshua.eaton@us.army.mil NR 8 TC 1 Z9 1 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1944-7620 BN 978-1-4673-3108-1; 978-1-4673-3107-4 J9 ANN IEEE SYST CONF PY 2013 BP 783 EP 790 PG 8 WC Computer Science, Information Systems; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BHV65 UT WOS:000326754400120 ER PT S AU Castelli, M Meier, T Morris, M Philie, M Kwinn, M AF Castelli, Mark Meier, Timothy Morris, Marquis Philie, Mathieu Kwinn, Michael GP IEEE TI The Federal Air Marshal Service Using Value Focused Thinking to Optimize Field Office Allocations SO 2013 7TH ANNUAL IEEE INTERNATIONAL SYSTEMS CONFERENCE (SYSCON 2013) SE Annual IEEE Systems Conference LA English DT Proceedings Paper CT 7th Annual IEEE International Systems Conference (SysCon) CY APR 15-18, 2013 CL Orlando, FL SP IEEE DE Federal Air Marshal Service; Value Focused Thinking AB The Federal Air Marshal Service's (FAMS) mission is to promote confidence in the nation's civil aviation system through effective deployment of Federal Air Marshals (FAMs) to detect, deter, and defeat hostile acts targeting United States air carriers, airports, passengers, and crews. To accomplish this mission, the FAMS has established field offices across the United States and assigned marshals to these offices. As with all of government, the FAMS continues to work to operate efficiently as well as effectively. To this end, they seek to determine the best field office and marshal assignment set to maximize risk coverage at the minimum cost. In this work, we take a two-phased approach to solve this problem: risk assessment and field office allocation. In the first phase, we use Value Focused Thinking (VFT) to formulate a detailed risk profile for each flight. In the second phase, we iteratively apply a separate application of VFT in a heuristic manner to determine the best from a set of assignment/field office alternatives until we achieve a near-optimal solution. Then, we use cost benefit analysis to decide among the final candidate solutions. The results provided in this study will be used by the FAMS to realign their field offices and the marshal allocation as well as provide the analytic rigor to defend their future budget submissions to Congress. Due to the sensitive nature of the assignment information, our presentation will focus on our approach and use derived vice actual data to obtain a solution set. C1 [Castelli, Mark; Meier, Timothy; Morris, Marquis; Philie, Mathieu; Kwinn, Michael] US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA. RP Castelli, M (reprint author), US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA. NR 9 TC 1 Z9 1 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1944-7620 BN 978-1-4673-3108-1; 978-1-4673-3107-4 J9 ANN IEEE SYST CONF PY 2013 BP 809 EP 811 PG 3 WC Computer Science, Information Systems; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BHV65 UT WOS:000326754400123 ER PT S AU Baker, SP Sadowski, RW AF Baker, Stuart P. Sadowski, Robert W. GP IEEE TI GPU Assisted Processing of Point cloud Data Sets for Ground Segmentation in Autonomous Vehicles SO 2013 IEEE INTERNATIONAL CONFERENCE ON TECHNOLOGIES FOR PRACTICAL ROBOT APPLICATIONS (TEPRA) SE IEEE International Conference on Technologies for Practical Robot Applications LA English DT Proceedings Paper CT IEEE International Conference on Technologies for Practical Robot Applications (TePRA) CY APR 22-23, 2013 CL Woburn, MA SP IEEE DE GPU; ground segmentation; LIDAR; point cloud AB In autonomous ground systems, developing a clear model of the surroundings is crucial for operating in any environment. Three-dimensional light detection and ranging (LIDAR) sensors, such as the Velodyne HDL-64E S2, are powerful tools for robotic perception. However, these sensors generate large data sets exceeding one million points per second that can be difficult to use on space, power, and processing constrained platforms. We report on GPU assisted processing within a Robotic Operating System (ROS) environment capable of achieving greater than an order of magnitude reduction in point cloud ground segmentation processing time using a gradient field algorithm with only a small increase in power consumption. C1 [Baker, Stuart P.; Sadowski, Robert W.] US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. RP Baker, SP (reprint author), US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. EM stuart.baker@usma.edu; robert.sadowski@usma.edu NR 13 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2325-0526 BN 978-1-4673-6225-2; 978-1-4673-6223-8 J9 IEEE INT CONF TECH PY 2013 PG 6 WC Engineering, Electrical & Electronic; Robotics SC Engineering; Robotics GA BHW04 UT WOS:000326807200009 ER PT S AU Maxwell, P Rykowski, J Hurlock, G AF Maxwell, Paul Rykowski, Joshua Hurlock, Gregory GP IEEE TI Proposal for the Initiation of General and Military Specific Benchmarking of Robotic Convoys SO 2013 IEEE INTERNATIONAL CONFERENCE ON TECHNOLOGIES FOR PRACTICAL ROBOT APPLICATIONS (TEPRA) SE IEEE International Conference on Technologies for Practical Robot Applications LA English DT Proceedings Paper CT IEEE International Conference on Technologies for Practical Robot Applications (TePRA) CY APR 22-23, 2013 CL Woburn, MA SP IEEE DE multi-robot systems; robotic benchmarks; convoys; military robotics AB This paper identifies the need for a standard method of benchmarking emerging robotic systems with a focus on military, multi-robot convoys. Benchmarking is commonly used throughout academia and industry as a method of evaluating and comparing products. In this paper we propose a generic form that these benchmarks may take in the future. Classification categories, such as, obstacle avoidance, area mapping, and convoy coherence are all possible elements of this benchmark. The goal is a standard benchmark that can be used to evaluate military multi-robot convoy systems. C1 [Maxwell, Paul; Rykowski, Joshua; Hurlock, Gregory] US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. RP Maxwell, P (reprint author), US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. EM paul.maxwell@usma.edu; joshua.rykowski@usma.edu; gregory.hurlock@us.army.mil NR 17 TC 0 Z9 0 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2325-0526 BN 978-1-4673-6225-2; 978-1-4673-6223-8 J9 IEEE INT CONF TECH PY 2013 PG 6 WC Engineering, Electrical & Electronic; Robotics SC Engineering; Robotics GA BHW04 UT WOS:000326807200012 ER PT J AU Pappas, DD Bujanda, AA Orlicki, JA Demaree, JD Hirvonen, JK Jensen, RE McKnight, SH AF Pappas, D. D. Bujanda, A. A. Orlicki, J. A. Demaree, J. D. Hirvonen, J. K. Jensen, R. E. McKnight, S. H. BE Thomas, M Mittal, KL TI Deposition of Nanosilica Coatings on Plasma Activated Polyethylene Films SO ATMOSPHERIC PRESSURE PLASMA TREATMENT OF POLYMERS: RELEVANCE TO ADHESION LA English DT Article; Book Chapter DE Polyethylene; dielectric barrier discharge; nanosilica ID DIELECTRIC BARRIER DISCHARGE; ATMOSPHERIC-PRESSURE; SURFACE MODIFICATION; MECHANICAL-PROPERTIES; POLYMER SURFACES; ADHESION; HELIUM; FIBERS; AIR; FILAMENTARY AB Covalent attachment of pre-formed nanosilica particles to the surface of ultra-high molecular weight polyethylene (UHMWPE) was attained through a grafting reaction using 3-glycidoxypropyltrimethoxysilane (GPS) once the surface had been exposed to a plasma treatment. Scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and contact angle measurements showed a change in both the morphology and composition of the surface with the appearance of micro-depressions, grafting of oxygen containing functional groups, and improved wettability upon exposure to the plasma. Attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and Rutherford backscattering spectrometry (RBS) confirmed that plasma activation and a silane intermediary were required for the efficient chemical grafting of the nanosilica. Attempts at grafting the nanosilica to as-received polyethylene films proved unsuccessful due to the absence of covalent bonding sites. C1 [Pappas, D. D.; Bujanda, A. A.; Orlicki, J. A.; Demaree, J. D.; Hirvonen, J. K.; Jensen, R. E.; McKnight, S. H.] US Army Res Lab, Aberdeen Proving Ground, MD USA. RP Pappas, DD (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD USA. NR 47 TC 0 Z9 0 U1 1 U2 6 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND BN 978-1-118-59621-0 PY 2013 BP 175 EP 197 D2 10.1002/9781118747308 PG 23 WC Physics, Fluids & Plasmas; Polymer Science SC Physics; Polymer Science GA BHY48 UT WOS:000327018200007 ER PT J AU Rodriguez-Santiago, V Bujanda, AA Strawhecker, KE Pappas, DD AF Rodriguez-Santiago, Victor Bujanda, Andres A. Strawhecker, Kenneth E. Pappas, Daphne D. BE Thomas, M Mittal, KL TI The Effect of Helium-Air, Helium-Water Vapor, Helium-Oxygen, and Helium-Nitrogen Atmospheric Pressure Plasmas on the Adhesion Strength of Polyethylene SO ATMOSPHERIC PRESSURE PLASMA TREATMENT OF POLYMERS: RELEVANCE TO ADHESION LA English DT Article; Book Chapter DE Dielectric barrier discharge; polyethylene; adhesion; roughness ID DIELECTRIC BARRIER DISCHARGE; SURFACE MODIFICATION; POLYMERS AB Non-thermal atmospheric-pressure plasmas, specifically dielectric barrier discharges (DBDs), have attracted significant attention due to their ease of formation of stable plasmas, low cost of operation, fast materials processing, and scalability. Furthermore, DBDs have been shown to be effective in functionalizing the surface of polymeric materials. In this study, the surface of ultra-high molecular weight polyethylene (UHMWPE) films was treated with He-air, He-H2O, He-O-2, and He-N-2 dielectric barrier discharges to assess the effect of the surface functionalization on their adhesion strength. Changes in wettability, surface chemistry, and surface morphology were studied using water contact angle goniometry, x-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), respectively. Adhesion was assessed using T-peel tests on all samples using a polyurethane adhesive. Results indicate that samples treated with He-H2O and He-O-2 plasmas had similar oxygen functionalities, however, He-O-2 plasmas caused significantly more roughening of the surface than He-H2O plasma. He-air and He-N-2 plasmas showed nitrogen incorporation to the surface in the form of amine, and possibly nitrate and amide groups, with the highest concentration at 4 atomic percent. In addition, He-air and He-N-2 plasmas were highly filamentary which caused increased roughness to the surface. Furthermore, He-air and He-N-2 had, similarly, high adhesion strength although they did not show the highest roughness. The adhesion strength of UHMWPE films exhibited the following trend He-air > He-N-2 > He-O-2 > He-H2O. These results indicate that He-air or He-N-2 plasmas are effective in treating polymer surfaces for adhesion purposes. C1 [Rodriguez-Santiago, Victor; Bujanda, Andres A.; Strawhecker, Kenneth E.; Pappas, Daphne D.] US Army Res Lab, Aberdeen Proving Ground, MD USA. RP Rodriguez-Santiago, V (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD USA. NR 18 TC 1 Z9 1 U1 0 U2 4 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND BN 978-1-118-59621-0 PY 2013 BP 299 EP 313 D2 10.1002/9781118747308 PG 15 WC Physics, Fluids & Plasmas; Polymer Science SC Physics; Polymer Science GA BHY48 UT WOS:000327018200012 ER PT B AU Kenyon, PL Twogood, G Summerlin, LA AF Kenyon, Peggy L. Twogood, Gary Summerlin, Linda A. BE Moore, MG TI DISTANCE EDUCATION IN THE ARMED FORCES SO HANDBOOK OF DISTANCE EDUCATION, 3RD EDITION LA English DT Article; Book Chapter C1 [Kenyon, Peggy L.] Off TRADOC Capabil Manager, Army Distributed Learning Program, Ft Eustis, VA 23604 USA. [Twogood, Gary] AETC A3IA Prod Integrat, Randolph Air Force Base, TX USA. [Twogood, Gary] Air Force Distance Learning, Wright Patterson AFB, OH USA. [Summerlin, Linda A.] US Army, Adelphi, MD USA. RP Kenyon, PL (reprint author), Off TRADOC Capabil Manager, Army Distributed Learning Program, Ft Eustis, VA 23604 USA. NR 9 TC 0 Z9 0 U1 0 U2 0 PU ROUTLEDGE PI LONDON PA 11 NEW FETTER LANE, LONDON EC4P 4EE, ENGLAND BN 978-0-415-89770-9; 978-0-203-80373-8; 978-0-415-89764-8 PY 2013 BP 641 EP 653 PG 13 WC Education & Educational Research SC Education & Educational Research GA BHX49 UT WOS:000326938600046 ER PT J AU Allen, JB Riveros, G AF Allen, Jeffrey B. Riveros, Guillermo TI Hydrodynamic Characterization of the Polyodon spathula Rostrum Using CFD SO JOURNAL OF APPLIED MATHEMATICS LA English DT Article ID SQUARE CYLINDER; PADDLEFISH AB Among the various functions of the paddlefish rostrum, it is also believed to serve as a stabilizer to counteract the downward force that would otherwise occur during the process of filter feeding. From its unique shape, it is hypothesized that the paddlefish rostrum serves to generate a substantial amount of lift that naturally occurs as the rostrum is elevated at the same time the fish opens its mouth. The present, numerical study is an attempt to quantify the amount of lift (and drag) that is generated by the rostrum of a juvenile paddlefish. Additionally, this data is compared with other hydrofoils. The results suggest that the paddlefish rostrum does indeed produce substantial lift at certain angles of attack. In fact, the results indicate that the amount of lift is comparable to that produced by a symmetric foil (NACA 0012). C1 [Allen, Jeffrey B.; Riveros, Guillermo] US Army Engn Res & Dev Ctr, Informat Technol Lab, ATTN CEERD IE C, Vicksburg, MS 39180 USA. RP Allen, JB (reprint author), US Army Engn Res & Dev Ctr, Informat Technol Lab, ATTN CEERD IE C, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM jeffrey.b.allen@usace.army.mil FU research programs: "Biostructural Analysis and Modeling: the Paddlefish Rostrum as a Structure for Bioinspiration" FX This research was performed as part of the US Army Engineer Research and Development Center Directed Research Programs. In particular, the authors gratefully acknowledge the funding support from the research programs: "Biostructural Analysis and Modeling: the Paddlefish Rostrum as a Structure for Bioinspiration." The authors thank the Chief of Engineers of the US Army Corps of Engineers for permission to publish this paper. NR 26 TC 0 Z9 0 U1 1 U2 17 PU HINDAWI PUBLISHING CORPORATION PI NEW YORK PA 410 PARK AVENUE, 15TH FLOOR, #287 PMB, NEW YORK, NY 10022 USA SN 1110-757X EI 1687-0042 J9 J APPL MATH JI J. Appl. Math. PY 2013 AR 346173 DI 10.1155/2013/346173 PG 8 WC Mathematics, Applied SC Mathematics GA 256GF UT WOS:000327297000001 ER PT J AU Escolas, SM Pitts, BL Safer, MA Bartone, PT AF Escolas, Sandra M. Pitts, Barbara L. Safer, Martin A. Bartone, Paul T. TI The Protective Value of Hardiness on Military Posttraumatic Stress Symptoms SO MILITARY PSYCHOLOGY LA English DT Article DE posttraumatic stress disorder; dispositional resilience; hardiness; military ID US ARMY; PSYCHOLOGICAL-RESILIENCE; PTSD CHECKLIST; SOCIAL SUPPORT; LIFE EVENTS; DISORDER; HEALTH; AFGHANISTAN; OPERATIONS; VETERANS AB This study examined the protective effects of hardiness (dispositional resilience) on self-reported posttraumatic stress disorder (PTSD) symptoms in a sample of postdeployed service members. Hardiness was negatively related to PTSD symptoms. Time in the military, number of deployments, and total time spent on deployment were all positively related to PTSD symptoms. Hardiness moderated the effects of time in the military on PTSD symptoms, such that time in the military had no effect on those who were high in hardiness. Hardiness did not moderate the effects of either deployment measure. Suggestions to modify current military resilience training programs to most effectively enhance the benefits of hardiness are discussed. C1 [Escolas, Sandra M.] US Army Inst Surg Res, Clin Div, San Antonio, TX USA. [Pitts, Barbara L.; Safer, Martin A.] Catholic Univ Amer, Dept Psychol, Washington, DC 20064 USA. [Bartone, Paul T.] Natl Def Univ, Ctr Technol & Natl Secur Policy, Taipei, Taiwan. RP Escolas, SM (reprint author), 3698 Chambers Pass, Ft Sam Houston, TX 78234 USA. EM sandie.escolas@us.army.mil OI Bartone, Paul/0000-0002-5767-0086 NR 31 TC 8 Z9 8 U1 4 U2 13 PU AMER PSYCHOLOGICAL ASSOC PI WASHINGTON PA 750 FIRST ST NE, WASHINGTON, DC 20002-4242 USA SN 0899-5605 EI 1532-7876 J9 MIL PSYCHOL JI Milit. Psychol. PY 2013 VL 25 IS 2 BP 116 EP 123 DI 10.1037/h0094953 PG 8 WC Psychology, Multidisciplinary SC Psychology GA 253BT UT WOS:000327057500003 ER PT J AU Carr, W Bradley, D Ogle, AD Eonta, SE Pyle, BL Santiago, P AF Carr, Walter Bradley, Devvon Ogle, Alan D. Eonta, Stephanie E. Pyle, Bryan L. Santiago, Patcho TI Resilience Training in a Population of Deployed Personnel SO MILITARY PSYCHOLOGY LA English DT Article DE resilience; military; training; deployment ID DEPRESSIVE SYMPTOMS; SCALE; CARE AB The U.S. military has developed prophylactic interventions to mitigate effects from stress. The project reported is a first of its kind descriptive assessment of the delivery of resilience training in a deployed environment. The Connor-Davidson Resilience Scale and an inventory of stress, morale, performance, and use of specific behaviors were administered before and after resilience training was implemented for all personnel assigned to a military facility in Afghanistan. There was a small positive relation between resilient thinking and self-reported morale, but, despite the training, both resilient thinking and morale were observed to decline across the deployment period. This descriptive effort can provide some baseline for commanders' expectations in implementation of resilience training. C1 [Carr, Walter; Eonta, Stephanie E.] Naval Med Res Ctr, Silver Spring, MD USA. [Bradley, Devvon] William Beaumont Army Med Ctr, El Paso, TX 79920 USA. [Ogle, Alan D.] Lackland AFB, Training Squadron 66, San Antonio, TX USA. [Pyle, Bryan L.] Fleet Family Support Ctr, Ft George G Meade, MD USA. [Santiago, Patcho] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA. RP Carr, W (reprint author), Walter Reed Army Inst Res, 503 Robert Grant Ave, Silver Spring, MD 20910 USA. EM walter.s.carr.mil@mail.mil RI Dopko, Rae/J-7437-2015 NR 19 TC 5 Z9 5 U1 2 U2 12 PU AMER PSYCHOLOGICAL ASSOC PI WASHINGTON PA 750 FIRST ST NE, WASHINGTON, DC 20002-4242 USA SN 0899-5605 EI 1532-7876 J9 MIL PSYCHOL JI Milit. Psychol. PY 2013 VL 25 IS 2 BP 148 EP 155 DI 10.1037/h0094956 PG 8 WC Psychology, Multidisciplinary SC Psychology GA 253BT UT WOS:000327057500006 ER PT J AU Kaber, DB Riley, JM Endsley, MR Sheik-Nainar, M Zhang, T Lampton, DR AF Kaber, David B. Riley, Jennifer M. Endsley, Mica R. Sheik-Nainar, Mohamed Zhang, Tao Lampton, Donald R. TI Measuring Situation Awareness in Virtual Environment-Based Training SO MILITARY PSYCHOLOGY LA English DT Article DE situation awareness measurement; military operations; virtual reality; simulation and training ID DYNAMIC-SYSTEMS; PERFORMANCE AB We evaluated the efficacy of a computer-based situation awareness (SA) measurement system for training dismounted infantry SA in an urban terrain virtual reality (VR) simulation. Based on past research, we hypothesized that the SA measures would be sensitive to individual (squad leader) differences, and that the frequency of specific probes would reveal differences in critical SA requirements among scenarios. Three infantry squads performed multiple trials across two different scenarios. A confederate platoon leader posed probes to squad leaders during trials and experts made ratings afterward. Results revealed squad leaders had similar responses to probes, despite differences in combat experience. Analysis of probe frequency revealed different high priority SA elements and decisions for each scenario. The SA behavior and communication ratings revealed differences among squads, which trended with experience. Measures of SA were also consistent across the test scenario as a result of similar mission types and task difficulties. We discuss the implication of our findings for future research and theory within this area. C1 [Kaber, David B.] N Carolina State Univ, Dept Ind & Syst Engn, Raleigh, NC 27695 USA. [Riley, Jennifer M.; Endsley, Mica R.] SA Technol Inc, Marietta, GA USA. [Sheik-Nainar, Mohamed] Synaptics Inc, Santa Clara, CA USA. [Zhang, Tao] Purdue Univ, W Lafayette, IN 47907 USA. [Lampton, Donald R.] US Army Res Inst Behav & Social Sci, Orlando, FL USA. RP Kaber, DB (reprint author), N Carolina State Univ, Dept Ind & Syst Engn, 111 Lampe Dr,400 Daniels Hall, Raleigh, NC 27695 USA. EM dbkaber@ncsu.edu NR 24 TC 0 Z9 0 U1 4 U2 18 PU AMER PSYCHOLOGICAL ASSOC PI WASHINGTON PA 750 FIRST ST NE, WASHINGTON, DC 20002-4242 USA SN 0899-5605 EI 1532-7876 J9 MIL PSYCHOL JI Milit. Psychol. PY 2013 VL 25 IS 4 BP 330 EP 344 DI 10.1037/h0095998 PG 15 WC Psychology, Multidisciplinary SC Psychology GA 253CC UT WOS:000327058400002 ER PT J AU Kazemi, DM Berry-Caban, CS Becker, C Hiebert, J AF Kazemi, Donna M. Berry-Caban, Cristobal S. Becker, Christopher Hiebert, Jean TI Review of Interventions Designed to Address Drinking Among Soldiers SO MILITARY PSYCHOLOGY LA English DT Review DE soldiers; alcohol use; intervention; review ID ALCOHOL-USE; ARMY SOLDIERS; US MILITARY; IRAQ; PROGRAM; AFGHANISTAN; PERSONNEL; FORCES; WAR AB Heavy and abusive alcohol use is a major health problem facing military service members. We reviewed literature on alcohol intervention programs targeting military personnel to assess the methodological quality and effectiveness of the programs. Although the search yielded more than 42,000 citations, only 150 met initial screening criteria. Eighteen studies had sufficient evidence to meet secondary screening and of these only 10 studies were included in the review. These studies employed several types of interventions, but only 1 used a randomized controlled trial. Our findings indicate that there is greater need to assess intervention strategies, and there is a particular need for high-quality studies using randomized controlled trials with standardized assessment tools to improve the generalizability of the findings. We discuss the implications of our findings for future research in this area. C1 [Kazemi, Donna M.] Univ N Carolina, Sch Nursing, Coll Hlth & Human Serv, Charlotte, NC 28223 USA. [Berry-Caban, Cristobal S.] Womack Army Med Ctr, Clin Investigat Serv, Ft Bragg, NC USA. [Becker, Christopher] Univ N Carolina, Dept Sociol, Charlotte, NC 28223 USA. [Hiebert, Jean] Univ N Carolina, J Murrey Atkins Lib, Charlotte, NC 28223 USA. RP Kazemi, DM (reprint author), Univ N Carolina, Sch Nursing, Coll Hlth & Human Serv, 9201 Univ City Blvd,CHHS 444C, Charlotte, NC 28223 USA. EM dkazemi@uncc.edu NR 29 TC 1 Z9 1 U1 3 U2 6 PU AMER PSYCHOLOGICAL ASSOC PI WASHINGTON PA 750 FIRST ST NE, WASHINGTON, DC 20002-4242 USA SN 0899-5605 EI 1532-7876 J9 MIL PSYCHOL JI Milit. Psychol. PY 2013 VL 25 IS 4 BP 365 EP 380 DI 10.1037/h0095999 PG 16 WC Psychology, Multidisciplinary SC Psychology GA 253CC UT WOS:000327058400005 ER PT J AU Yingst, SL Izadjoo, M Hoover, DL AF Yingst, Samuel L. Izadjoo, Mina Hoover, David L. TI CD8 Knockout Mice Are Protected from Challenge by Vaccination with WR201, a Live Attenuated Mutant of Brucella melitensis SO CLINICAL & DEVELOPMENTAL IMMUNOLOGY LA English DT Article ID T-CELL; BALB/C MICE; ABORTUS INFECTION; INTRACELLULAR BACTERIA; GAMMA-INTERFERON; IMMUNE-RESPONSE; CD4(+); IMMUNIZATION; LYMPHOCYTES; ACTIVATION AB CD8+ T cells have been reported to play an important role in defense against B. abortus infection in mouse models. In the present report, we use CD8 knockout mice to further elucidate the role of these cells in protection from B. melitensis infection. Mice were immunized orally by administration of B. melitensis WR201, a purine auxotrophic attenuated vaccine strain, then challenged intranasally with B. melitensis 16M. In some experiments, persistence of WR201 in the spleens of CD8 knockout mice was slightly longer than that in the spleens of normal mice. However, development of anti-LPS serum antibody, antigen-induced production of gamma-interferon (IFN-gamma) by immune splenic lymphocytes, protection against intranasal challenge, and recovery of nonimmunized animals from intranasal challenge were similar between normal and knockout animals. Further, primary Brucella infection was not exacerbated in perforin knockout and Fas-deficient mice and these animals' anti-Brucella immune responses were indistinguishable from those of normal mice. These results indicate that CD8+ T cells do not play an essential role as either cytotoxic cells or IFN-gamma producers, yet they do participate in a specific immune response to immunization and challenge in this murine model of B. melitensis infection. C1 [Yingst, Samuel L.] Walter Reed Army Inst Res, Dept Bacterial Dis, Silver Spring, MD 20910 USA. [Yingst, Samuel L.] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand. [Izadjoo, Mina] Henry M Jackson Fdn Adv Mil Med, Diagnost & Translat Res Ctr, Gaithersburg, MD 20879 USA. [Hoover, David L.] DHMD Consulting LLC, Rockville, MD 20853 USA. RP Yingst, SL (reprint author), Walter Reed Army Inst Res, Dept Bacterial Dis, Silver Spring, MD 20910 USA. EM samuel.yingst@afrims.org FU Department of Defense Military Infectious Diseases Research Program FX This work was supported by funding from the Department of Defense Military Infectious Diseases Research Program. The authors honor the memory of the late Dr. Ela Zelazowska whose work was an invaluable contribution to this effort. NR 39 TC 3 Z9 3 U1 0 U2 2 PU HINDAWI PUBLISHING CORPORATION PI NEW YORK PA 410 PARK AVENUE, 15TH FLOOR, #287 PMB, NEW YORK, NY 10022 USA SN 1740-2522 EI 1740-2530 J9 CLIN DEV IMMUNOL JI Clin. Dev. Immunol. PY 2013 AR 686919 DI 10.1155/2013/686919 PG 7 WC Immunology SC Immunology GA 250GI UT WOS:000326838100001 ER PT J AU Cahill, R Lund, JR DeOreo, B Medellin-Azuara, J AF Cahill, R. Lund, J. R. DeOreo, B. Medellin-Azuara, J. TI Household water use and conservation models using Monte Carlo techniques SO HYDROLOGY AND EARTH SYSTEM SCIENCES LA English DT Article ID DEMAND MANAGEMENT; SHORTAGE; PRICE AB The increased availability of end use measurement studies allows for mechanistic and detailed approaches to estimating household water demand and conservation potential. This study simulates water use in a single-family residential neighborhood using end-water-use parameter probability distributions generated from Monte Carlo sampling. This model represents existing water use conditions in 2010 and is calibrated to 2006-2011 metered data. A two-stage mixed integer optimization model is then developed to estimate the least-cost combination of long- and short-term conservation actions for each household. This least-cost conservation model provides an estimate of the upper bound of reasonable conservation potential for varying pricing and rebate conditions. The models were adapted from previous work in Jordan and are applied to a neighborhood in San Ramon, California in the eastern San Francisco Bay Area. The existing conditions model produces seasonal use results very close to the metered data. The least-cost conservation model suggests clothes washer rebates are among most cost-effective rebate programs for indoor uses. Retrofit of faucets and toilets is also cost-effective and holds the highest potential for water savings from indoor uses. This mechanistic modeling approach can improve understanding of water demand and estimate cost-effectiveness of water conservation programs. C1 [Cahill, R.] US Army Corps Engineers, Portland, OR USA. [Lund, J. R.; Medellin-Azuara, J.] Univ Calif Davis, Ctr Watershed Sci, Davis, CA 95616 USA. [DeOreo, B.] Aquacraft Inc, Boulder, CO USA. RP Cahill, R (reprint author), US Army Corps Engineers, Portland, OR USA. EM ryan.cahill@usace.army.mil NR 28 TC 5 Z9 5 U1 3 U2 33 PU COPERNICUS GESELLSCHAFT MBH PI GOTTINGEN PA BAHNHOFSALLEE 1E, GOTTINGEN, 37081, GERMANY SN 1027-5606 EI 1607-7938 J9 HYDROL EARTH SYST SC JI Hydrol. Earth Syst. Sci. PY 2013 VL 17 IS 10 BP 3957 EP 3967 DI 10.5194/hess-17-3957-2013 PG 11 WC Geosciences, Multidisciplinary; Water Resources SC Geology; Water Resources GA 247FZ UT WOS:000326603200019 ER PT S AU Meyers, RE Deacon, KS Tunick, A AF Meyers, Ronald E. Deacon, Keith S. Tunick, Arnold BE Meyers, RE Shih, Y Deacon, KS TI Turbulence-Free Space-Time Quantum Imaging SO QUANTUM COMMUNICATIONS AND QUANTUM IMAGING XI SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Quantum Communications and Quantum Imaging XI CY AUG 26-29, 2013 CL San Diego, CA SP SPIE AB We experimentally demonstrate turbulence-free space-time quantum imaging. Quantum images of remote objects are produced with two sensors measuring at different space-time points under turbulent conditions. The quantum images generated move depending on the time delay between the two sensor measurements and the speed of a rotating ground glass that is part of a chaotic laser light source. For small delay times turbulence has virtually no adverse affect on the moving quantum images. The experimental setup and findings contribute to understanding the fundamentals of multi-photon quantum interference in complex media. Furthermore, the space-time memory demonstrated in our research provides important new pathways for investigating quantum imaging, quantum information storage and quantum computing. The turbulence-free space-time quantum imaging procedure greatly increases the information content of each photon measured. The moved quantum images are in fact new images that are stored in a space-time virtual memory process. The images are stored within the same quantum imaging data sets and thus quantum imaging can produce more information per photon measured than was previously realized. C1 [Meyers, Ronald E.; Deacon, Keith S.; Tunick, Arnold] Army Res Lab, Adelphi, MD 20783 USA. RP Meyers, RE (reprint author), Army Res Lab, Adelphi, MD 20783 USA. EM ronald.e.meyers6.civ@mail.mil NR 10 TC 0 Z9 0 U1 0 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9725-3 J9 PROC SPIE PY 2013 VL 8875 AR 88750X DI 10.1117/12.2028191 PG 6 WC Optics; Physics, Applied; Imaging Science & Photographic Technology; Telecommunications SC Optics; Physics; Imaging Science & Photographic Technology; Telecommunications GA BHU77 UT WOS:000326703000021 ER PT S AU Meyers, RE Deacon, KS Tunick, A AF Meyers, Ronald E. Deacon, Keith S. Tunick, Arnold BE Meyers, RE Shih, Y Deacon, KS TI Space-Time Quantum Imaging SO QUANTUM COMMUNICATIONS AND QUANTUM IMAGING XI SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Quantum Communications and Quantum Imaging XI CY AUG 26-29, 2013 CL San Diego, CA SP SPIE AB We report on an experimental demonstration of quantum imaging where the images are stored in both space and time. Quantum images of remote objects are produced with rotating ground glass induced chaotic laser light and two sensors measuring at different space-time points. Quantum images are observed to move depending on the time delay between the sensor measurements. The experiments provide a new testbed for exploring the time and space scale fundamental physics of quantum imaging and suggest new pathways for quantum information storage and processing. The moved quantum images are in fact new images that are stored in a space-time virtual memory process. The images are stored within the same quantum imaging data sets and thus quantum imaging can produce more information per photon measured than was previously realized. C1 [Meyers, Ronald E.; Deacon, Keith S.; Tunick, Arnold] Army Res Lab, Adelphi, MD 20783 USA. RP Meyers, RE (reprint author), Army Res Lab, Adelphi, MD 20783 USA. EM ronald.e.meyers6.civ@mail.mil NR 8 TC 0 Z9 0 U1 0 U2 1 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9725-3 J9 PROC SPIE PY 2013 VL 8875 AR 887502 DI 10.1117/12.2028190 PG 6 WC Optics; Physics, Applied; Imaging Science & Photographic Technology; Telecommunications SC Optics; Physics; Imaging Science & Photographic Technology; Telecommunications GA BHU77 UT WOS:000326703000001 ER PT J AU Payne, ZM Lamichhane, KM Babcock, RW Turnbull, SJ AF Payne, Zachary M. Lamichhane, Krishna M. Babcock, Roger W., Jr. Turnbull, Stephen J. TI Pilot-scale in situ bioremediation of HMX and RDX in soil pore water in Hawaii SO ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS LA English DT Article ID ENERGETIC MATERIALS; LIVE-FIRE; EXPLOSIVES; RESIDUES; TNT; HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE; BIODEGRADATION; TRANSPORT; RANGES; FATE AB A nine-month in situ bioremediation study was conducted in Makua Military Reservation (MMR) in Oahu, Hawaii (USA) to evaluate the potential of molasses to enhance biodegradation of royal demolition explosive (RDX) and high-melting explosive (HMX) contaminated soil below the root zone. MMR has been in operation since the 1940's resulting in subsurface contamination that in some locations exceeds USEPA preliminary remediation goals for these chemicals. A molasses-water mixture (1 : 40 dilution) was applied to a treatment plot and clean water was applied to a control plot via seven flood irrigation events. Pore water samples were collected from 12 lysimeters installed at different depths in 3 boreholes in each test plot. The difference in mean concentrations of RDX in pore water samples from the two test plots was very highly significant (p < 0.001). The concentrations differences with depth were also very highly significant (p < 0.001) and degradation was greatly enhanced at depths from 5 to 13.5 ft. biodegradation was modeled as first order and the rate constant was 0.063 per day at 5 ft and decreased to 0.023 per day at 11 ft to 13.5 ft depth. Enhanced biodegradation of HMX was also observed in molasses treated plot samples but only at a depth of 5 ft. The difference in mean TOC concentration (surrogate for molasses) was highly significant with depth (p = 0.003) and very highly significant with treatment (p < 0.001). Mean total nitrogen concentrations also differed significantly with treatment (p < 0.001) and depth (p = 0.059). The molasses water mixture had a similar infiltration rate to that of plain water (average 4.12 ft per day) and reached the deepest sensor (31 ft) within 5 days of application. Most of the molasses was consumed by soil microorganisms by about 13.5 feet below ground surface and treatment of deeper depths may require greater molasses concentrations and/or more frequent flood irrigation. Use of the bioremediation method described herein could allow the sustainable use of live fire training ranges by enhancing biodegradation of explosives in situ and preventing them from migrating to through the vadose zone to underlying ground water and off-site. C1 [Payne, Zachary M.] Environet Inc, Honolulu, HI 96813 USA. [Lamichhane, Krishna M.; Babcock, Roger W., Jr.] Univ Hawaii, Dept Civil & Environm Engn, Honolulu, HI 96822 USA. [Turnbull, Stephen J.] US Army Garrison, Directorate Publ Works, Schofield Barracks, HI 96857 USA. RP Babcock, RW (reprint author), Univ Hawaii, Dept Civil & Environm Engn, 2540 Dole St,Holmes 383, Honolulu, HI 96822 USA. EM zpayne@environetinc.com; lamichha@hawaii.edu; rbabcock@hawaii.edu; steve.j.turnbull@us.army.mil NR 30 TC 1 Z9 1 U1 1 U2 14 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 2050-7887 EI 2050-7895 J9 ENVIRON SCI-PROC IMP JI Environ. Sci.-Process Impacts PY 2013 VL 15 IS 11 BP 2023 EP 2029 DI 10.1039/c3em00320e PG 7 WC Chemistry, Analytical; Environmental Sciences SC Chemistry; Environmental Sciences & Ecology GA 242LT UT WOS:000326244100004 PM 24061783 ER PT J AU Amirbahman, A Massey, DI Lotufo, G Steenhaut, N Brown, LE Biedenbach, JM Magar, VS AF Amirbahman, Aria Massey, Delia I. Lotufo, Guilherme Steenhaut, Nicholas Brown, Lauren E. Biedenbach, James M. Magar, Victor S. TI Assessment of mercury bioavailability to benthic macroinvertebrates using diffusive gradients in thin films (DGT) SO ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS LA English DT Article ID AMPHIPOD LEPTOCHEIRUS-PLUMULOSUS; ACID VOLATILE SULFIDE; SEDIMENT-BOUND METALS; FRESH-WATER SEDIMENT; IN-SITU MEASUREMENTS; TRACE-METALS; CONTAMINATED SEDIMENTS; NATURAL-WATERS; METHYL MERCURY; TRANSPLANTED MUSSELS AB Mercury-specific diffusive gradient in thin films (DGTs) were used in laboratory microcosms as a biomonitoring tool to assess the lability of mercury (Hg) total and monomethylmercury Hg (MeHg), and to develop a relationship between chemical lability and bioavailability in estuarine sediments. Time-series deployment of DGTs in sediments showed that sediment-bound MeHg is more labile than sediment-bound inorganic Hg. In subsequent experiments, DGTs were deployed simultaneously with three benthic macroinvertebrates (the estuarine amphipod, Leptocheirus plumulosus; the estuarine polychaete, Nereis virens; and the marine clam, Macoma nasuta) in sediments for up to 55 days. All organisms and their co-deployed DGTs exhibited an initial period of rapid Hg uptake followed by slower uptake reaching apparent steady state. Strong correlative relationships were generally observed between paddle-type DGTs and macroinvertebrate tissue data (r(2) between 0.57 and 0.97). Further, %MeHg: Total Hg ratios for M. nasuta and N. virens (38.5 +/- 12.2 and 19.2 +/- 5.2) were similar to their corresponding ratios for the DGTs (33.1 +/- 13.3 and 24.4 +/- 11.0), and they were significantly higher than the same ratios for sediment (2.9 +/- 0.3) and pore water (8.5 +/- 4.9). The %MeHg: Total Hg ratios for L. plumulosus (68.5 +/- 6.2) were significantly higher than those for the DGTs. This may be because the tissue and DGT data for this organism were not truly co-located as L. plumulosus burrows close to the sediment surface, and the DGTs sampled the sediment surface. Overall, our results suggest that for benthic macroinvertebrates in estuarine sediments studied here, (a) sediment MeHg is more bioavailable than inorganic Hg, (b) sediment and pore-water concentration measurements are not good predictors for the extent of bioaccumulation of Hg species, and (c) DGTs are an effective biomonitoring tool for the assessment of bioavailability of Hg species. C1 [Amirbahman, Aria; Massey, Delia I.] Univ Maine, Dept Civil & Environm Engn, Orono, ME 04469 USA. [Lotufo, Guilherme; Biedenbach, James M.] US Army Corps Engineers, Engn Res & Dev Ctr, Vicksburg, MS 39180 USA. [Steenhaut, Nicholas] ENVIRON Int Corp, Boston, MA 02110 USA. [Brown, Lauren E.] ENVIRON Int Corp, Portland, MA 04101 USA. [Magar, Victor S.] ENVIRON Int Corp, Chicago, IL 60606 USA. RP Amirbahman, A (reprint author), Univ Maine, Dept Civil & Environm Engn, Orono, ME 04469 USA. EM aria@umit.maine.edu FU Strategic Environmental Research and Development Program (SERDP) project [ER-1771] FX Funding for this work was provided by a grant from the Strategic Environmental Research and Development Program (SERDP) project ER-1771. Three anonymous reviewers are acknowledged for their constructive comments. NR 64 TC 7 Z9 7 U1 13 U2 52 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 2050-7887 EI 2050-7895 J9 ENVIRON SCI-PROC IMP JI Environ. Sci.-Process Impacts PY 2013 VL 15 IS 11 BP 2104 EP 2114 DI 10.1039/c3em00355h PG 11 WC Chemistry, Analytical; Environmental Sciences SC Chemistry; Environmental Sciences & Ecology GA 242LT UT WOS:000326244100013 PM 24084872 ER PT B AU Howard, RD AF Howard, Russell D. BE Kieh, GK Kalu, K TI Global terrorism and US counter-terrorism policy in West Africa SO WEST AFRICA AND THE U.S. WAR ON TERROR SE Routledge Studies in US Foreign Policy LA English DT Article; Book Chapter C1 [Howard, Russell D.] US Army, Adelphi, MD USA. [Howard, Russell D.] Monterey Inst, Int Terrorism Res & Educ Program MonTREP, Monterey, CA USA. [Howard, Russell D.] US Mil Acad, Dept Social Sci, West Point, NY USA. [Howard, Russell D.] Fletcher Sch, Combating Terrorism Ctr West Point, West Point, NY USA. [Howard, Russell D.] Fletcher Sch, Jebsen Ctr Counter Terrorism Studies, West Point, NY USA. [Howard, Russell D.] Harvard Univ, Ctr Int Affairs, Cambridge, MA 02138 USA. RP Howard, RD (reprint author), Howards Global Solut, Monterey, CA 93940 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ROUTLEDGE PI LONDON PA 11 NEW FETTER LANE, LONDON EC4P 4EE, ENGLAND BN 978-0-203-10482-8; 978-0-415-53942-5 J9 ROUT STUD US FOR POL PY 2013 BP 71 EP 86 PG 16 WC International Relations; Political Science SC International Relations; Government & Law GA BHS72 UT WOS:000326584500006 ER PT S AU Severson, B St Leger, A AF Severson, Brian St Leger, Aaron GP IEEE TI Feasibility Study of Photovoltaic Panels in Military Temporary Housing Structures SO 2013 IEEE GREEN TECHNOLOGIES CONFERENCE SE IEEE Green Technologies Conference LA English DT Proceedings Paper CT IEEE Green Technologies Conference (GREENTECH) CY APR 04-05, 2013 CL Denver, CO SP IEEE, IEEE Comp Soc, Boeing, URS, CCET, IEEE Denver Sect, IEEE Reg 5, IEEE USA DE Photovoltaic system; Renewable energy; Solar energy AB Energy consumption by the US Army is becoming an increasingly important issue. The cost of providing fuel to Army outposts in deployed environments is particularly expensive due to numerous precautions required to defend fuel convoys from enemy attacks. This work is part of the Army's Construction Engineering Research Laboratory (CERL) efforts to reduce the amount of energy consumed by temporary barracks structures commonly referred to as "B-Huts". A prototype is being developed utilizing structurally insulated panels (SIP) and is referred to as a "SIP-Hut". This paper explores the benefits of incorporating photovoltaic (PV) panels into the SIP-Hut's power system. Powering a SIP-Hut is a unique challenge because SIP-Huts are typically located in remote and dangerous locations and, in addition, are temporary structures. A main thrust of this work was to examine if PV could be economically beneficial within this unique environment and short time span. However, the findings from this study can be applied to other remote locations where fossil fuels are not readily available. The SIP-Hut was modeled, solar resources estimated and analysis was performed using Hybrid Optimization Model for Electric Renewable (HOMER) software. Our analysis indicates that PV incorporation can have a significant positive impact on the amount of diesel fuel consumed and the overall cost of energy production. C1 [Severson, Brian; St Leger, Aaron] US Mil Acad, West Point, NY 10966 USA. RP Severson, B (reprint author), US Mil Acad, West Point, NY 10966 USA. EM brian.severson@usma.edu; aaron.stleger@usma.edu NR 5 TC 5 Z9 5 U1 0 U2 7 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2166-546X BN 978-0-7695-4966-8 J9 IEEE GREEN TECHNOL PY 2013 BP 78 EP 84 DI 10.1109/GreenTech.2013.20 PG 7 WC Engineering, Electrical & Electronic SC Engineering GA BHL31 UT WOS:000325778400012 ER PT B AU Ezekannagha, C Jasien, T Kim, SH Springer, J AF Ezekannagha, Chiazo Jasien, Trexler Kim, Sung-Hoon Springer, Jordan GP IEEE TI Analysis of Changes to Tobyhanna Army Depot Maintenance Cycle SO 2013 IEEE SYSTEMS AND INFORMATION ENGINEERING DESIGN SYMPOSIUM (SIEDS) LA English DT Proceedings Paper CT IEEE Systems and Information Engineering Design Symposium (SIEDS) CY APR 26, 2013 CL Univ Virginia, Charlottesville, VA SP IEEE HO Univ Virginia AB As part of a year-long study for the Department of Systems Engineering at West Point, our Capstone project seeks to provide Tobyhanna Army Depot with a decision support tool that will quantify how changes in Depot Maintenance programs, to include the exploration of reset and recap maintenance for the AN/TPQ 37 Firefinder will affect the readiness, time, cost, reliability, and support costs of the Firefinder. The AN/TPQ 37 Firefinder is a mobile radar system that provides detection of incoming artillery and rocket fire and tracks its movement in order to provide a location for counter-battery fire. This study is important because it incorporates an interdisciplinary approach to solving a complex problem using elements of industrial engineering, systems thinking, as well as modeling in producing a decision support tool that will allow Tobyhanna to make changes to their resources and service times in order to analyze these effects on turnaround times. The problem will be solved in two phases. The first phase will be to model the current operations at Tobyhanna Army Depot by using the AnyLogic simulation tool. This will be done by analyzing maintenance data and using the AnyLogic simulation tool in order to model their current system turnaround of 180 days. Once this is complete and approved by Tobyhanna Army Depot, inputs in AnyLogic will be altered in order to show how these changes will impact service turnaround times. So far, we have achieved an average turnaround time of 6 months with our current model. We have also succeeded in providing a decision support tool to Tobyhanna Army Depot that will allow them to alter their resource and labor constraints in order to accurately model what its impact on turnaround time will be. C1 [Ezekannagha, Chiazo; Jasien, Trexler; Kim, Sung-Hoon; Springer, Jordan] US Mil Acad, Dept Syst Engn, West Point, NY 10997 USA. RP Ezekannagha, C (reprint author), US Mil Acad, Dept Syst Engn, West Point, NY 10997 USA. EM Chiazo.ezekannagha@usma.edu; William.jasien@usma.edu; Sung-hoon.kim@usma.edu; Jordan.springer@usma.edu NR 4 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-5663-3; 978-1-4673-5662-6 PY 2013 BP 37 EP 40 PG 4 WC Computer Science, Theory & Methods; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BHJ70 UT WOS:000325637100007 ER PT B AU Wangeman, SJ AF Wangeman, Stephanie J. GP IEEE TI IED Dataset Generation: Analysis Across Theaters SO 2013 IEEE SYSTEMS AND INFORMATION ENGINEERING DESIGN SYMPOSIUM (SIEDS) LA English DT Proceedings Paper CT IEEE Systems and Information Engineering Design Symposium (SIEDS) CY APR 26, 2013 CL Univ Virginia, Charlottesville, VA SP IEEE HO Univ Virginia AB Improvised Explosive Devices are the most dangerous threat to United States troops in Iraq and Afghanistan. Regardless of where troops deploy next, there is a strong likelihood of IED use in future conflicts. While great progress in analysis and exploitation of IED data has been made, the data is generally limited to historical attacks in current theaters of operation. The purpose of this analysis is to develop a tool that generates IED placement data based on statistically valid assumptions and distributions in any theater. These distributions can be used to train analysts prior to deployment to new environments. The research will generate data representing hypothetical IED attacks in a table structured like the CIDNE database. IED data from the CIDNE database will be used to develop distributions for each attack detailing IED location and type (type includes: command detonated, victim detonated, timer operated and radio controlled). Hypotheses will be tested using CIDNE data to determine some trends, including: seasonality, distance from road and location relative to terrain features. Results of these tests will shape the distributions used in the generation of synthetic datasets. The datasets will be generated based on road networks, terrain and population centers in Colorado, but shape files could be used from any region of the world. The results will generate various datasets that can be used for training analysts on IED attacks specific to any Operating Environment. This simulation will expose analysts to realistic data better preparing them for combat operations in their theater. C1 US Mil Acad, West Point, NY 10996 USA. RP Wangeman, SJ (reprint author), US Mil Acad, West Point, NY 10996 USA. EM stephanie.wangeman@usma.edu NR 8 TC 1 Z9 1 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-5663-3; 978-1-4673-5662-6 PY 2013 BP 92 EP 97 PG 6 WC Computer Science, Theory & Methods; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BHJ70 UT WOS:000325637100017 ER PT S AU Grueneberg, K de Mel, G Braines, D Wang, XP Calo, S Pham, T AF Grueneberg, Keith de Mel, Geeth Braines, Dave Wang, Xiping Calo, Seraphin Pham, Tien BE Pham, T Kolodny, MA Priddy, KL TI Context-Rich Semantic Framework for Effective Data-to-Decisions in Coalition Networks SO GROUND/AIR MULTISENSOR INTEROPERABILITY, INTEGRATION, AND NETWORKING FOR PERSISTENT ISR IV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Ground/Air Multisensor Interoperability, Integration, and Networking for Persistent ISR IV CY APR 29-MAY 02, 2013 CL Baltimore, MD SP SPIE DE semantic web; natural language processing; context; semantic enrichment AB In a coalition context, data fusion involves combining of soft (e. g., field reports, intelligence reports) and hard (e. g., acoustic, imagery) sensory data such that the resulting output is better than what it would have been if the data are taken individually. However, due to the lack of explicit semantics attached with such data, it is difficult to automatically disseminate and put the right contextual data in the hands of the decision makers. In order to understand the data, explicit meaning needs to be added by means of categorizing and/or classifying the data in relationship to each other from base reference sources. In this paper, we present a semantic framework that provides automated mechanisms to expose real-time raw data effectively by presenting appropriate information needed for a given situation so that an informed decision could be made effectively. The system utilizes controlled natural language capabilities provided by the ITA (International Technology Alliance) Controlled English (CE) toolkit to provide a human-friendly semantic representation of messages so that the messages can be directly processed in human/machine hybrid environments. The Real-time Semantic Enrichment (RTSE) service adds relevant contextual information to raw data streams from domain knowledge bases using declarative rules. The rules define how the added semantics and context information are derived and stored in a semantic knowledge base. The software framework exposes contextual information from a variety of hard and soft data sources in a fast, reliable manner so that an informed decision can be made using semantic queries in intelligent software systems. C1 [Grueneberg, Keith; de Mel, Geeth; Wang, Xiping; Calo, Seraphin] IBM Corp, Thomas J Watson Res Ctr, Yorktown Hts, NY 10598 USA. [Braines, Dave] IBM United Kingdom Ltd, London, England. [Pham, Tien] US Army Res Lab, Washington, DC USA. RP Grueneberg, K (reprint author), IBM Corp, Thomas J Watson Res Ctr, Yorktown Hts, NY 10598 USA. FU U.S. Army Research Laboratory (ARL); U.K. Ministry of Defence [W911NF-06-3-0001] FX This research was sponsored by the U.S. Army Research Laboratory (ARL) and the U.K. Ministry of Defence and was accomplished under Agreement Number W911NF-06-3-0001. The views and conclusions contained in this document are those of the author(s) and should not be interpreted as representing the official policies, either expressed or implied, of the U.S. ARL, the U.S. Government, the U.K. Ministry of Defence or the U.K. Government. The U.S. and U.K. Governments are authorized to reproduce and distribute reprints for Government purposes notwithstanding any copyright notation hereon. NR 22 TC 0 Z9 0 U1 0 U2 1 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9533-4 J9 PROC SPIE PY 2013 VL 8742 AR UNSP 874202 DI 10.1117/12.2018022 PG 11 WC Engineering, Electrical & Electronic; Optics; Telecommunications SC Engineering; Optics; Telecommunications GA BHK82 UT WOS:000325750300002 ER PT S AU Marcus, K Cannata, J AF Marcus, Kelvin Cannata, Jess BE Pham, T Kolodny, MA Priddy, KL TI Dynamically Allocated Virtual Clustering Management System SO GROUND/AIR MULTISENSOR INTEROPERABILITY, INTEGRATION, AND NETWORKING FOR PERSISTENT ISR IV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Ground/Air Multisensor Interoperability, Integration, and Networking for Persistent ISR IV CY APR 29-MAY 02, 2013 CL Baltimore, MD SP SPIE DE Virtualization; cloud; clustering; emulation; dynamic; test bed; virtual machine; network emulation AB The U.S Army Research Laboratory (ARL) has built a "Wireless Emulation Lab" to support research in wireless mobile networks. In our current experimentation environment, our researchers need the capability to run clusters of heterogeneous nodes to model emulated wireless tactical networks where each node could contain a different operating system, application set, and physical hardware. To complicate matters, most experiments require the researcher to have root privileges. Our previous solution of using a single shared cluster of statically deployed virtual machines did not sufficiently separate each user's experiment due to undesirable network crosstalk, thus only one experiment could be run at a time. In addition, the cluster did not make efficient use of our servers and physical networks. To address these concerns, we created the Dynamically Allocated Virtual Clustering management system (DAVC). This system leverages existing open-source software to create private clusters of nodes that are either virtual or physical machines. These clusters can be utilized for software development, experimentation, and integration with existing hardware and software. The system uses the Grid Engine job scheduler to efficiently allocate virtual machines to idle systems and networks. The system deploys stateless nodes via network booting. The system uses 802.1Q Virtual LANs (VLANs) to prevent experimentation crosstalk and to allow for complex, private networks eliminating the need to map each virtual machine to a specific switch port. The system monitors the health of the clusters and the underlying physical servers and it maintains cluster usage statistics for historical trends. Users can start private clusters of heterogeneous nodes with root privileges for the duration of the experiment. Users also control when to shutdown their clusters. C1 [Marcus, Kelvin] US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20873 USA. [Cannata, Jess] R Systems NA Inc, Champaign, IL USA. RP Marcus, K (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20873 USA. NR 2 TC 1 Z9 1 U1 0 U2 4 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9533-4 J9 PROC SPIE PY 2013 VL 8742 AR UNSP 87420X DI 10.1117/12.2018514 PG 10 WC Engineering, Electrical & Electronic; Optics; Telecommunications SC Engineering; Optics; Telecommunications GA BHK82 UT WOS:000325750300026 ER PT S AU Ostashev, VE Collier, SL Reiff, CG Cheinet, S Ligon, DA Wilson, DK Noble, JM Alberts, WC AF Ostashev, Vladimir E. Collier, Sandra L. Reiff, Christian G. Cheinet, Sylvain Ligon, David A. Wilson, D. Keith Noble, John M. Alberts, William C. BE Pham, T Kolodny, MA Priddy, KL TI Source localization results for airborne acoustic platforms in the 2010 Yuma Proving Ground test SO GROUND/AIR MULTISENSOR INTEROPERABILITY, INTEGRATION, AND NETWORKING FOR PERSISTENT ISR IV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Ground/Air Multisensor Interoperability, Integration, and Networking for Persistent ISR IV CY APR 29-MAY 02, 2013 CL Baltimore, MD SP SPIE DE Airborne acoustic sensors; source localization; refraction corrections AB Acoustic sensors are being employed on airborne platforms, such as Persistent Threat Detection System (PTDS) and Persistent Ground Surveillance System (PGSS), for source localization. Under certain atmospheric conditions, airborne sensors offer a distinct advantage over ground sensors. Among other factors, the performance of airborne sensors is affected by refraction of sound signals due to vertical gradients in temperature and wind velocity. A comprehensive experiment in source localization with an aerostat-mounted acoustic system was conducted in summer of 2010 at Yuma Proving Ground (YPG). Acoustic sources on the ground consisted of one-pound TNT denotations and small arms firings. The height of the aerostat was approximately 1 km above the ground. In this paper, horizontal, azimuthal, and elevation errors in source localization and their statistics are studied in detail. Initially, straight-line propagation is assumed; then refraction corrections are introduced to improve source localization and decrease the errors. The corrections are based on a recently developed theory [Ostashev, et. al, JASA 2008] which accounts for sound refraction due to vertical profiles of temperature and wind velocity. During the 2010 YPG field test, the vertical profiles were measured only up to a height of approximately 100 m. Therefore, the European Center for Medium-range Weather Forecasts (ECMWF) is used to generate the profiles for July of 2010. C1 [Ostashev, Vladimir E.] Univ Colorado, CIRES, 325 Broadway, Boulder, CO 80305 USA. [Collier, Sandra L.; Reiff, Christian G.; Ligon, David A.; Noble, John M.; Alberts, William C.] US Army Res Lab, Adelphi, MD 20783 USA. [Cheinet, Sylvain] French German Inst Saint Louis, F-68300 St Louis, France. [Wilson, D. Keith] US Army, Engn Res & Dev Ctr, Hanover, NH 03755 USA. RP Ostashev, VE (reprint author), Univ Colorado, CIRES, 325 Broadway, Boulder, CO 80305 USA. EM vladimir.ostashev@noaa.gov RI Wilson, D. Keith/A-4687-2012 OI Wilson, D. Keith/0000-0002-8020-6871 NR 10 TC 0 Z9 0 U1 0 U2 4 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9533-4 J9 PROC SPIE PY 2013 VL 8742 AR UNSP 87420K DI 10.1117/12.2015152 PG 9 WC Engineering, Electrical & Electronic; Optics; Telecommunications SC Engineering; Optics; Telecommunications GA BHK82 UT WOS:000325750300015 ER PT S AU Tati, S Novotny, P Ko, BJ Wolf, A Swami, A La Porta, T AF Tati, Srikar Novotny, Petr Ko, Bong Jun Wolf, Alexander Swami, Ananthram La Porta, Thomas BE Pham, T Kolodny, MA Priddy, KL TI Diagnosing Degradation of Services in Hybrid Wireless Tactical Networks SO GROUND/AIR MULTISENSOR INTEROPERABILITY, INTEGRATION, AND NETWORKING FOR PERSISTENT ISR IV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Ground/Air Multisensor Interoperability, Integration, and Networking for Persistent ISR IV CY APR 29-MAY 02, 2013 CL Baltimore, MD SP SPIE DE service management; hybrid wireless tactical networks; cross-layer framework; service-layer dependency graph ID MOBILITY MANAGEMENT AB In this paper, we consider a problem related to service management and deployment in tactical military networks. Tactical networks are typically hybrid wireless networks in which there are both static and mobile nodes with several wireless interfaces, such as 802.11, 3G, satellite, etc. In tactical networks, performance degradation in services could prove fatal, so it must be diagnosed quickly. This degradation could be due to mobility or bottlenecks in capacity at network layer. We provide a cross-layer framework to detect and diagnose these causes of performance degradation as part of service management; it includes a monitoring model of services and a network model for hybrid wireless networks. In addition, we give a working example in tactical military networks to illustrate our framework. We provide an experimental setup to simulate our hybrid wireless tactical network scenario along with preliminary results. C1 [Tati, Srikar; La Porta, Thomas] Penn State Univ, University Pk, PA 16802 USA. [Novotny, Petr; Wolf, Alexander] Univ London Imperial Coll Sci Technol & Med, London SW7 2AZ, England. [Ko, Bong Jun] IBM Corp, Thomas J Watson Res Ctr, Yorktown Hts, NY 10598 USA. [Swami, Ananthram] Army Res Lab, Adelphi, MD 20783 USA. RP Tati, S (reprint author), Penn State Univ, University Pk, PA 16802 USA. EM tati@cse.psu.edu; p.novotny09@imperial.ac.uk; bongjunko@us.ibm.com; a.wolf@imperial.ac.uk; aswami@arl.army.mil; tlp@cse.psu.edu FU U.S. Army Research Laboratory; U.K. Ministry of Defence [W911NF-06-3-0001] FX This research was sponsored by the U.S. Army Research Laboratory and the U.K. Ministry of Defence and was accomplished under Agreement Number W911NF-06-3-0001. The views and conclusions contained in this document are those of the author(s) and should not be interpreted as representing the official policies, either expressed or implied, of the U.S. Army Research Laboratory, the U.S. Government, the U.K. Ministry of Defence or the U.K. Government. The U.S. and U.K. Governments are authorized to reproduce and distribute reprints for Government purposes notwithstanding any copyright notation hereon. NR 8 TC 0 Z9 0 U1 0 U2 0 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9533-4 J9 PROC SPIE PY 2013 VL 8742 AR UNSP 874210 DI 10.1117/12.2018097 PG 6 WC Engineering, Electrical & Electronic; Optics; Telecommunications SC Engineering; Optics; Telecommunications GA BHK82 UT WOS:000325750300029 ER PT S AU Toth, A Bergamaschi, F AF Toth, Andrew Bergamaschi, Flavio BE Pham, T Kolodny, MA Priddy, KL TI Characterization and definition of a software stack for a reference experimental framework SO GROUND/AIR MULTISENSOR INTEROPERABILITY, INTEGRATION, AND NETWORKING FOR PERSISTENT ISR IV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Ground/Air Multisensor Interoperability, Integration, and Networking for Persistent ISR IV CY APR 29-MAY 02, 2013 CL Baltimore, MD SP SPIE DE network emulation; network simulation; experimentation; software stack AB In 2006, the US Army Research Laboratory (ARL) and the UK Ministry of Defence (MoD) established a collaborative research alliance with academia and industry, named the International Technology Alliance in Network and Information Science (ITA) 1 to address fundamental issues concerning Network and Information Sciences. Research performed under the ITA was extended through a collaboration between ARL and IBM UK to characterize and define a software stack and tooling that will become the reference framework for network science experimentation. A key element to the success and validation of ITA theoretical research is experimentation in a controlled environment that can, as best as possible, emulate the real world conditions and context. Experimental validation in a network emulation environment contributes to the validation of theoretical concepts and algorithms, the investigation of more complex scenarios that span multiple research areas, exposing gaps in the theory that may need special attention, identifying additional areas where the research might focus and develop, and reproducible experimentation, which enables and facilitates the comparison of results from multiple executions of the same experiment. To accomplish these experimentation goals, the framework needs to foster the collaboration across multiple disciplines and facilitate the sharing of existing and new assets in a common emulation environment. The framework also needs to be extensible for the integration of new features, emulation models, monitoring, and integration with real, external assets that can be linked to any given experiment. This paper discusses the work resulting from the ARL/ IBM UK collaboration to build a framework to support experimentations and foster collaboration within and across different research groups. C1 [Toth, Andrew] US Army Res Lab, Adelphi, MD USA. [Bergamaschi, Flavio] BM United Kingdom Ltd, London, England. RP Toth, A (reprint author), US Army Res Lab, Adelphi, MD USA. FU US Army Research laboratory; UK Ministry of Defense [W911NF-06-3-0001] FX This research was in parts sponsored by US Army Research laboratory and the UK Ministry of Defense and was accomplished under Agreement Number W911NF-06-3-0001. The views and conclusions contained in this document are those of the authors and should not be interpreted as representing the official policies, either expressed or implied, of the US Army Research Laboratory, the U.S. Government, the UK Ministry of Defense, or the UK Government. The US and UK Governments are authorized to reproduce and distribute reprints for Government purposes notwithstanding any copyright notation hereon. NR 31 TC 0 Z9 0 U1 0 U2 1 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9533-4 J9 PROC SPIE PY 2013 VL 8742 AR UNSP 87420Y DI 10.1117/12.2018535 PG 11 WC Engineering, Electrical & Electronic; Optics; Telecommunications SC Engineering; Optics; Telecommunications GA BHK82 UT WOS:000325750300027 ER PT S AU Klem, E Lewis, J Gregory, C Cunningham, G Temple, D D'Souza, A Robinson, E Wijewarnasuriya, PS Dhar, N AF Klem, Ethan Lewis, Jay Gregory, Chris Cunningham, Garry Temple, Dorota D'Souza, Arvind Robinson, Ernest Wijewarnasuriya, P. S. Dhar, Nibir BE LeVan, PD Sood, AK Wijewarnasuriya, PS DSouza, AI TI High-performance SWIR sensing from colloidal quantum dot photodiode arrays SO INFRARED SENSORS, DEVICES, AND APPLICATIONS III SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Infrared Sensors, Devices, and Applications III CY AUG 26-28, 2013 CL San Diego, CA SP SPIE DE Quantum Dot; SWIR; Detector; Photodiode ID PHOTODETECTORS; DEVICES AB RTI has demonstrated a novel photodiode technology based on IR-absorbing solution-processed PbS colloidal quantum dots (CQD) that can overcome the high cost, limited spectral response, and challenges in the reduction in pixel size associated with InGaAs focal plane arrays. The most significant advantage of the CQD technology is ease of fabrication. The devices can be fabricated directly onto the ROIC substrate at low temperatures compatible with CMOS, and arrays can be fabricated at wafer scale. Further, device performance is not expected to degrade significantly with reduced pixel size. We present results for upward-looking detectors fabricated on Si substrates with sensitivity from the UV to similar to 1.7 mu m, compare these results to InGaAs detectors, and present measurements of the CQD detectors temperature dependent dark current. C1 [Klem, Ethan; Lewis, Jay; Gregory, Chris; Cunningham, Garry; Temple, Dorota] RTI Int, 3040 Cornwallis Rd, Res Triangle Pk, NC 27709 USA. [D'Souza, Arvind; Robinson, Ernest] DRS Sensors & Targeting Syst, Cypress, CA 90630 USA. [Wijewarnasuriya, P. S.] US Army, Res Lab, Adelphi, MD 20783 USA. [Dhar, Nibir] DARPA, MTO, Arlington, VA 22203 USA. RP Klem, E (reprint author), RTI Int, 3040 Cornwallis Rd, Res Triangle Pk, NC 27709 USA. NR 9 TC 1 Z9 1 U1 0 U2 6 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9718-5 J9 PROC SPIE PY 2013 VL 8868 AR UNSP 886806 DI 10.1117/12.2026972 PG 6 WC Optics; Physics, Applied SC Optics; Physics GA BHN50 UT WOS:000325975200005 ER PT S AU Sood, AK Pethuraja, G Sood, AW Welser, RE Puri, YR Haldar, P Schubert, EF Dhar, NK Wijewarnasuriya, PS AF Sood, Ashok K. Pethuraja, Gopal Sood, Adam W. Welser, Roger E. Puri, Yash R. Haldar, Pradeep Schubert, E. Fred Dhar, Nibir K. Wijewarnasuriya, Priyalal S. BE LeVan, PD Sood, AK Wijewarnasuriya, PS DSouza, AI TI DEVELOPMENT OF LARGE AREA NANOSTRUCTRED AR COATINGS FOR EO/IR SENSOR APPLICATIONS SO INFRARED SENSORS, DEVICES, AND APPLICATIONS III SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Infrared Sensors, Devices, and Applications III CY AUG 26-28, 2013 CL San Diego, CA SP SPIE ID LOW-REFRACTIVE-INDEX; ANTIREFLECTION COATINGS; TECHNOLOGY AB Electro-optical/infrared nanosensors are being developed for a variety of defense and commercial systems applications. One of the critical technologies that will enhance EO/IR sensor performance is the development of advanced antireflection coatings with both broadband and omnidirectional characteristics. In this paper, we review our latest work on high quality nanostructure-based antireflection structures, including recent efforts to deposit nanostructured antireflection coatings on large area substrates. Nanostructured antireflection coatings fabricated via oblique angle deposition are shown to enhance the optical transmission through transparent windows by minimizing broadband reflection losses to less than one percent, a substantial improvement over conventional thin-film antireflection coating technologies. Step-graded antireflection structures also exhibit excellent omnidirectional performance, and have recently been demonstrated on 6-inch diameter substrates. C1 [Sood, Ashok K.; Pethuraja, Gopal; Sood, Adam W.; Welser, Roger E.; Puri, Yash R.] Magnolia Opt Technol Inc, 52-B Cummings Pk,Suite 314, Woburn, MA USA. [Haldar, Pradeep] CNSE, Albany, NY 12222 USA. [Schubert, E. Fred] Rensselaer Polytech Inst, Dept ECSE & Phys, Troy, NY 12180 USA. [Dhar, Nibir K.] DARPA MTO, Arlington, VA 22203 USA. [Wijewarnasuriya, Priyalal S.] US Army, Res Lab, Adelphi, MD 20783 USA. RP Sood, AK (reprint author), Magnolia Opt Technol Inc, 52-B Cummings Pk,Suite 314, Woburn, MA USA. RI Pethuraja, Gopal/D-9976-2015 OI Pethuraja, Gopal/0000-0001-9789-5645 NR 14 TC 1 Z9 1 U1 1 U2 11 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9718-5 J9 PROC SPIE PY 2013 VL 8868 AR UNSP 88680P DI 10.1117/12.2032206 PG 10 WC Optics; Physics, Applied SC Optics; Physics GA BHN50 UT WOS:000325975200020 ER PT S AU Tian, ZB DeCuir, EA Gautam, N Krishna, S Wijewarnasuriya, PS Pattison, JW Dhar, N Welser, RE Sood, AK AF Tian, Z. -B. DeCuir, E. A., Jr. Gautam, N. Krishna, S. Wijewarnasuriya, P. S. Pattison, J. W. Dhar, N. Welser, R. E. Sood, A. K. BE LeVan, PD Sood, AK Wijewarnasuriya, PS DSouza, AI TI Hetero-engineering infrared detectors with type-II superlattices SO INFRARED SENSORS, DEVICES, AND APPLICATIONS III SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Infrared Sensors, Devices, and Applications III CY AUG 26-28, 2013 CL San Diego, CA SP SPIE DE infrared; photodetectors; type-II superlattice; unipolar barrier; pBiBn; interband cascade scheme AB InAs/GaSb type-II superlattices (T2-SLs) are of great interest as they provide a lot of band engineering flexibility. A wide variety of unipolar barrier structures have been investigated with this material system. In this report, we will present our recent work on the development of low noise long-wave infrared (LWIR) InAs/GaSb T2-SLs photodetectors. By adopting a so-called pBiBn design, the dark current of LWIR photodetectors is greatly suppressed. The LWIR pBiBn device has demonstrated a dark current density as low as 1.42x10(-5) A/cm(2) at -60 mV, and R(0)A of 5365 Omega cm(2) at 76 K. A peak detectivity at 7.8 mu m of 7.7x10(11) cmHz(1/2)W(-1) is obtained at 76 K. Further effort to reduce the operating bias is also reported. By refining the energy-band alignment, a 2-mu m-thick LWIR pBiBn device has demonstrated a single pass (no AR coating) quantum efficiency of 20% at 10 mu m under zero-bias at 77 K. We have recently extended our efforts to further reduce the dark current by using an interband cascade (IC) photodetector structure. Some further details about the device operation and results will be discussed. C1 [Tian, Z. -B.; Gautam, N.; Krishna, S.] Univ New Mexico, Ctr High Technol Mat, Albuquerque, NM 87106 USA. [DeCuir, E. A., Jr.; Wijewarnasuriya, P. S.; Pattison, J. W.] US Army, Res Lab, Adelphi, MD 20783 USA. [Dhar, N.] DARPA MTO, Arlington, VA 22203 USA. [Welser, R. E.; Sood, A. K.] Magnolia Opt Technol Inc, Woburn, MA 01801 USA. RP Tian, ZB (reprint author), Univ New Mexico, Ctr High Technol Mat, Albuquerque, NM 87106 USA. EM skrishna@chtm.unm.edu RI Tian, Zhaobing/C-9705-2011 FU DARPA Phase II SBIR Program FX We would like to acknowledge the funding support under DARPA Phase II SBIR Program. NR 16 TC 1 Z9 1 U1 1 U2 6 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9718-5 J9 PROC SPIE PY 2013 VL 8868 AR UNSP 88680L DI 10.1117/12.2032205 PG 9 WC Optics; Physics, Applied SC Optics; Physics GA BHN50 UT WOS:000325975200016 ER PT J AU Zhang, SS AF Zhang, Sheng S. TI A Concept for Making Poly(ethylene oxide) Based Composite Gel Polymer Electrolyte Lithium/Sulfur Battery SO JOURNAL OF THE ELECTROCHEMICAL SOCIETY LA English DT Article ID HIGH-CAPACITY DENSITY; SULFUR BATTERIES; ELECTROCHEMICAL PROPERTIES; POLYELECTROLYTE; PERFORMANCE; NANOTUBES; FIBERS AB We report a new concept for making poly(ethylene oxide) (PEO) based composite gel polymer electrolyte (CGPE) lithium batteries by demonstrating the fabrication of a lithium/sulfur (Li/S) cell, in which the CGPE is in situ formed by gelling a 50PEO-50SiO(2) (wt) composite membrane with a gel-forming liquid electrolyte. The composite membrane can be either coated onto the sulfur cathode to form an electrode-supporting electrode-membrane-assemble (EMA) or cast onto a Teflon substrate to form a freestanding membrane. Attributed to the presence of a large amount of inorganic SiO2 filler, the membrane can instantly absorb and retain various types of electrolyte solvents and ionic liquids without shrinkage. Using a gel-forming liquid electrolyte, the CGPE Li/S cell can be facilely prepared by heating an electrolyte-activated cell. In this paper, we demonstrate the preparation of a freestanding and highly flexible 50PEO-50SiO(2) composite membrane, and discuss the electrochemical characteristics of its resulting CGPE and the CGPE Li/S cell. (C) 2013 The Electrochemical Society. C1 US Army Res Lab, Electrochem Branch, RDRL SED C, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA. RP Zhang, SS (reprint author), US Army Res Lab, Electrochem Branch, RDRL SED C, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA. EM shengshui.zhang.civ@mail.mil RI Zhang, Sheng/A-4456-2012 OI Zhang, Sheng/0000-0003-4435-4110 NR 22 TC 16 Z9 16 U1 17 U2 132 PU ELECTROCHEMICAL SOC INC PI PENNINGTON PA 65 SOUTH MAIN STREET, PENNINGTON, NJ 08534 USA SN 0013-4651 EI 1945-7111 J9 J ELECTROCHEM SOC JI J. Electrochem. Soc. PY 2013 VL 160 IS 9 BP A1421 EP A1424 DI 10.1149/2.058309jes PG 4 WC Electrochemistry; Materials Science, Coatings & Films SC Electrochemistry; Materials Science GA 220PY UT WOS:000324600600014 ER PT J AU Stark, JK Ding, Y Kohl, PA AF Stark, Johanna K. Ding, Yi Kohl, Paul A. TI Nucleation of Electrodeposited Lithium Metal: Dendritic Growth and the Effect of Co-Deposited Sodium SO JOURNAL OF THE ELECTROCHEMICAL SOCIETY LA English DT Article ID CHLOROALUMINATE MOLTEN-SALTS; LITHIUM/POLYMER CELLS; ELECTROCHEMICAL DEPOSITION; ELECTROLYTE-SOLUTIONS; LIQUID ELECTROLYTE; MECHANISMS; BATTERIES; MORPHOLOGY; STABILITY; CARBONATE AB Higher energy density batteries are desired, especially for mobile electronic devices. Lithium metal anodes are a possible route to achieving high energy and power density due to their light weight compared to current graphite anodes. However, whisker growth during lithium electrodeposition (i.e. charging) represents a serious safety and efficiency concern for both lithium metal batteries and overcharging of graphite anodes in lithium-ion batteries. The initial morphology of deposited lithium nuclei can have a significant impact on the bulk material deposited. The nucleation of lithium metal from an organic ethylene carbonate: dimethyl carbonate (EC:DMC) and an ionic liquid (trimethylbutylammonium bis(triflouromethanesulfonyl)imide) electrolyte has been studied. Whisker extrusion and tip-based dendrite growth was observed ex-situ, and confirmed by in-situ optical microscopy experiments. The nucleation of a non-dendritic sodium co-deposit is also discussed. A model based on nuclei geometry is provided which gives insight into the deposition rate at constant overpotential. (C) 2013 The Electrochemical Society. All rights reserved. C1 [Stark, Johanna K.; Kohl, Paul A.] Georgia Inst Technol, Sch Chem & Bimol Engn, Atlanta, GA 30332 USA. [Ding, Yi] US Army RDECOM TARDEC, AMSRD TAR R, Warren, MI 48397 USA. RP Stark, JK (reprint author), Georgia Inst Technol, Sch Chem & Bimol Engn, Atlanta, GA 30332 USA. EM kohl@gatech.edu FU US Army [US001-0000245070] FX The authors gratefully acknowledge the financial support of the US Army, contract US001-0000245070. NR 32 TC 24 Z9 24 U1 16 U2 98 PU ELECTROCHEMICAL SOC INC PI PENNINGTON PA 65 SOUTH MAIN STREET, PENNINGTON, NJ 08534 USA SN 0013-4651 EI 1945-7111 J9 J ELECTROCHEM SOC JI J. Electrochem. Soc. PY 2013 VL 160 IS 9 BP D337 EP D342 DI 10.1149/2.028309jes PG 6 WC Electrochemistry; Materials Science, Coatings & Films SC Electrochemistry; Materials Science GA 220PY UT WOS:000324600600058 ER PT J AU Kiss, AM Myles, TD Grew, KN Peracchio, AA Nelson, GJ Chiu, WKS AF Kiss, Andrew M. Myles, Timothy D. Grew, Kyle N. Peracchio, Aldo A. Nelson, George J. Chiu, Wilson K. S. TI Carbonate and Bicarbonate Ion Transport in Alkaline Anion Exchange Membranes SO JOURNAL OF THE ELECTROCHEMICAL SOCIETY LA English DT Article ID WATER DIFFUSION-COEFFICIENTS; FUEL-CELLS; NAFION MEMBRANES; CONDUCTIVITY; DIOXIDE; MEDIA; TEMPERATURE; DESORPTION; HYDROXIDE; HYDRATION AB Anion exchange membranes (AEMs) are being developed for potential use in fuel cell systems which include portable power applications. In a fuel cell, these membranes transport hydroxide ions from the cathode to the anode. If carbon dioxide is present, carbonate and bicarbonate ions can form, displacing the hydroxide ions. Among the challenges this presents, the carbonate and bicarbonate are less mobile than the hydroxide and therefore the ionic conductivity of the membrane suffers. A procedure is outlined to take data from a permeation based water flux experiment and determine diffusion coefficients and the ionic conductivity of the membrane. The water-membrane diffusion coefficients can be measured from a water flux experiment. Using principles from kinetic theory, the water-membrane diffusion coefficient can be converted to an appropriate ion-membrane diffusion coefficient. Finally, an equation derived from the dusty fluid model can be used to calculate the ionic conductivity of the membrane in different counter ion forms. The calculated ionic conductivities have been shown to agree well with reported values for proton and anion exchange membranes. (C) 2013 The Electrochemical Society. All rights reserved. C1 [Kiss, Andrew M.; Myles, Timothy D.; Peracchio, Aldo A.; Nelson, George J.; Chiu, Wilson K. S.] Univ Connecticut, Dept Mech Engn, Storrs, CT 06269 USA. [Grew, Kyle N.] US Army Res Lab, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA. RP Kiss, AM (reprint author), Univ Connecticut, Dept Mech Engn, Storrs, CT 06269 USA. EM wchiu@engr.uconn.edu OI Kiss, Andrew/0000-0002-8515-5508 FU Army Research Office [W911NF-12-1-0148]; U.S. Department of the Army; U.S. Army Materiel Command FX Financial support from the Army Research Office (award number W911NF-12-1-0148) is gratefully acknowledged. KNG gratefully acknowledges support from the U.S. Department of the Army and U.S. Army Materiel Command. NR 34 TC 14 Z9 14 U1 2 U2 17 PU ELECTROCHEMICAL SOC INC PI PENNINGTON PA 65 SOUTH MAIN STREET, PENNINGTON, NJ 08534 USA SN 0013-4651 EI 1945-7111 J9 J ELECTROCHEM SOC JI J. Electrochem. Soc. PY 2013 VL 160 IS 9 BP F994 EP F999 DI 10.1149/2.037309jes PG 6 WC Electrochemistry; Materials Science, Coatings & Films SC Electrochemistry; Materials Science GA 220PY UT WOS:000324600600089 ER PT S AU Sensoy, M de Mel, G Fokoue, A Norman, TJ Pan, JZ Tang, YQ Oren, N Sycara, K Kaplan, L Pham, T AF Sensoy, Murat de Mel, Geeth Fokoue, Achille Norman, Timothy J. Pan, Jeff Z. Tang, Yuqing Oren, Nir Sycara, Katia Kaplan, Lance Tien Pham BE Broome, BD Hall, DL Llinas, J TI Reasoning with Uncertain Information and Trust SO NEXT-GENERATION ANALYST SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Next-Generation Analyst CY APR 29-30, 2013 CL Baltimore, MD SP SPIE DE Information Fusion; Trust; Uncertainty; Description Logics AB A limitation of standard Description Logics is its inability to reason with uncertain and vague knowledge. Although probabilistic and fuzzy extensions of DLs exist, which provide an explicit representation of uncertainty, they do not provide an explicit means for reasoning about second order uncertainty. Dempster-Shafer theory of evidence (DST) overcomes this weakness and provides means to fuse and reason about uncertain information. In this paper, we combine DL-Lite with DST to allow scalable reasoning over uncertain semantic knowledge bases. Furthermore, our formalism allows for the detection of conflicts between the fused information and domain constraints. Finally, we propose methods to resolve such conflicts through trust revision by exploiting evidence regarding the information sources. The effectiveness of the proposed approaches is shown through simulations under various settings. C1 [Sensoy, Murat] Ozyegin Univ, Istanbul, Turkey. [de Mel, Geeth; Fokoue, Achille] IBM TJ Watson Res Ctr, Armonk, NY USA. [de Mel, Geeth; Kaplan, Lance; Tien Pham] US Army Res Lab, Adelphi, MD USA. [Tang, Yuqing; Sycara, Katia] Carnegie Melon Univ, Pittsburg, KS USA. [Sensoy, Murat; Norman, Timothy J.; Oren, Nir] Univ Aberdeen, Comp Sci, Aberdeen AB9 1FX, Scotland. RP Sensoy, M (reprint author), Ozyegin Univ, Istanbul, Turkey. EM murat.sensoy@ozyegin.edu.tr FU U.S. Army Research Laboratory; U.K. Ministry of Defence [W911NF-06-3-0001] FX This research was sponsored by the U.S. Army Research Laboratory and the U.K. Ministry of Defence and was accomplished under Agreement Number W911NF-06-3-0001. The views and conclusions contained in this document are those of the authors and should not be interpreted as representing the official policies, either expressed or implied, of the U.S Army Research Laboratory, the U.S. Government, the U.K. Ministry of Defense or the U.K Government. The U.S. and U.K. Governments are authorized to reproduce and distribute for Government purposes notwithstanding any copyright notation hereon. NR 18 TC 0 Z9 0 U1 0 U2 1 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9549-5 J9 PROC SPIE PY 2013 VL 8758 AR UNSP 87580C DI 10.1117/12.2015667 PG 12 WC Computer Science, Artificial Intelligence; Computer Science, Information Systems; Optics SC Computer Science; Optics GA BHI31 UT WOS:000325494100009 ER PT B AU Teng, Y Jones, R Marusich, L O'Donovan, J Gonzalez, C Hollerer, T AF Teng, Yun Jones, Rashaad Marusich, Laura O'Donovan, John Gonzalez, Cleotilde Hoellerer, Tobias GP IEEE TI Trust and Situation Awareness in a 3-Player Diner's Dilemma Game SO 2013 IEEE INTERNATIONAL MULTI-DISCIPLINARY CONFERENCE ON COGNITIVE METHODS IN SITUATION AWARENESS AND DECISION SUPPORT (COGSIMA) LA English DT Proceedings Paper CT 3rd IEEE International Multi-Disciplinary Conference on Cognitive Methods in Situation Awareness and Decision Support (CogSIMA) CY FEB 25-28, 2013 CL San Diego, CA SP IEEE, SoarTech, Lockheed Martin, Calspan Univ Buffalo Res Ctr DE Diner's Dilemma; Multi-Player Trust Game; Trust; SA; User Interfaces ID CONFLICT AB This paper studies the relationship between trust and Situation Awareness (SA) in a 3-Player Iterated Diner's Dilemma game. We ran an experiment in which 24 participants each played against two computer opponents for six blocks of gameplay, with different opponent strategies in each block. Based on SA theory and design principles, we developed three different user interfaces, each supporting a specific SA Level. Each SA Level is inclusive of components from the previous level(s). We assess several trust-related metrics during the study, including percentage of cooperation over time and subjective level of self-reported trust towards the opponents, and analyze the interdependencies of trust, SA, and opponent strategy. Results from the experiment reveal highest levels of cooperation at SA Level 1 overall, and a higher level of cooperation for the group of cooperation-encouraging opponent strategies at SA Level 1 and 2 compared to cooperation-discouraging strategies. There is also a positive relationship between self-reported trust in the opponents and cooperation behavior for these strategies, but this relationship was not present in the cooperation-discouraging group. These results show that participants do respond to strategy type in terms of behavior, and that cooperation level is an indicator of the trust that participants place in the opponent players when cooperation emerges. C1 [Teng, Yun; O'Donovan, John; Hoellerer, Tobias] Univ Calif Santa Barbara, Dept Comp Sci, Santa Barbara, CA 93106 USA. [Jones, Rashaad] SA Technol, Santa Clara, CA 95054 USA. [Marusich, Laura] Army Res Lab, Adelphi, MD 20783 USA. [Gonzalez, Cleotilde] Carnegie Mellon Univ, Dept Social & Decis Sci, Pittsburgh, PA 15213 USA. RP Teng, Y (reprint author), Univ Calif Santa Barbara, Dept Comp Sci, Santa Barbara, CA 93106 USA. FU U.S. Army Research Laboratory [W911NF - 09 - 2 - 0053]; NSF [IIS - 1058132] FX This material is based in part upon work supported by the U.S. Army Research Laboratory under Cooperative Agreement No. W911NF - 09 - 2 - 0053 and by NSF grant IIS - 1058132. NR 16 TC 2 Z9 2 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-2437-3; 978-1-4673-2436-6 PY 2013 BP 9 EP 15 PG 7 WC Computer Science, Artificial Intelligence; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BHJ01 UT WOS:000325568600002 ER PT S AU Rosario, D AF Rosario, Dalton BE Shen, SS Lewis, PE TI A Multistage Framework for Dismount Spectral Verification in the VNIR SO ALGORITHMS AND TECHNOLOGIES FOR MULTISPECTRAL, HYPERSPECTRAL, AND ULTRASPECTRAL IMAGERY XIX SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Algorithms and Technologies for Multispectral, Hyperspectral, and Ultraspectral Imagery XIX CY APR 29-MAY 02, 2013 CL Baltimore, MD SP SPIE DE dismount verification; hyperspectral; skin detection ID FACE RECOGNITION; IMAGES AB A multistage algorithm suite is proposed for a specific target detection/verification scenario, where a visible/near infrared hyperspectral (HS) sample is assumed to be available as the only cue from a reference image frame. The target is a suspicious dismount. The suite first applies a biometric based human skin detector to focus the attention of the search. Using as reference all of the bands in the spectral cue, the suite follows with a Bayesian Lasso inference stage designed to isolate pixels representing the specific material type cued by the user and worn by the human target (e.g., hat, jacket). In essence, the search focuses on testing material types near skin pixels. The third stage imposes an additional constraint through RGB color quantization and distance metric checking, limiting even further the search for material types in the scene having visible color similar to the target visible color. Using the proposed cumulative evidence strategy produced some encouraging range-invariant results on real HS imagery, dramatically reducing to zero the false alarm rate on the example dataset. These results were in contrast to the results independently produced by each one of the suite's stages, as the spatial areas of each stage's high false alarm outcome were mutually exclusive in the imagery. These conclusions also apply to results produced by other standard methods, in particular the kernel SVDD (support vector data description) and matched filter, as shown in the paper. C1 US Army Res Lab, Adelphi, MD 20783 USA. RP Rosario, D (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 16 TC 0 Z9 0 U1 0 U2 2 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9534-1 J9 PROC SPIE PY 2013 VL 8743 AR 87430E DI 10.1117/12.2015411 PG 11 WC Optics; Spectroscopy SC Optics; Spectroscopy GA BHH00 UT WOS:000325394800010 ER PT S AU Liu, KC Ghoshal, A AF Liu, Kuang C. Ghoshal, Anindya BE Goulbourne, NC Naguib, HE TI Lamb wave dispersion under finite plastic deformation SO BEHAVIOR AND MECHANICS OF MULTIFUNCTIONAL MATERIALS AND COMPOSITES 2013 SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Behavior and Mechanics of Multifunctional Materials and Composites CY MAR 10-14, 2013 CL San Diego, CA SP SPIE, Amer Soc Mech Engineers DE wave propagation; elastodynamics; Lamb waves; plasticity; finite deformation ID ULTRASONIC NONDESTRUCTIVE EVALUATION; MICROSTRUCTURAL CHANGES; SOLID MATERIALS AB This paper presents a preliminary study of the effects residual plastic strains have on Lamb wave velocities and time of flight measurements. The potential application of this research is non-destructive evaluation and structural health monitoring, particularly reconstructing plastic strain fields. The finite deformation of a semi-infinite plate due to residual plastic strain is used to accommodate the changes in plate thickness and elongation. The results show that the S-0 mode exhibits significant variations in group velocity in the highly dispersive regions, as much as a 2% increase in velocity with a 1% plastic strain. However, for time of flight measurements, the plate elongation had an order of magnitude effect rather than showing velocity changes. By exploiting time delay measurements, it may be possible to use wave speed measurements to determine plastic zones through Lamb-like waves. C1 [Liu, Kuang C.; Ghoshal, Anindya] US Army, Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Liu, KC (reprint author), US Army, Res Lab, Aberdeen Proving Ground, MD 21005 USA. EM kuang.c.liu@gmail.com NR 8 TC 0 Z9 0 U1 0 U2 5 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9472-6 J9 PROC SPIE PY 2013 VL 8689 AR 86890A DI 10.1117/12.2012072 PG 9 WC Materials Science, Multidisciplinary; Materials Science, Composites; Optics SC Materials Science; Optics GA BGK42 UT WOS:000323320000007 ER PT J AU Ervin, MH Pereira, CM Miller, JR Outlaw, RA Rastegar, J Murray, RT AF Ervin, M. H. Pereira, C. M. Miller, J. R. Outlaw, R. A. Rastegar, J. Murray, R. T. TI Graphene-Based and Other Electrochemical Double Layer Capacitors for Energy Harvesting Systems SO ECS JOURNAL OF SOLID STATE SCIENCE AND TECHNOLOGY LA English DT Article AB A piezoelectric energy harvesting system that generates energy from the oscillation of a mass-spring and stores the energy on a capacitor is being developed for replacing batteries in some applications. Typically, this energy is stored in an electrolytic capacitor. Here, we explore a number of electrolytic- and electrochemical double layer capacitors (EDLCs, aka supercapacitors), including a graphene-array-based EDLC, for storing this energy. EDLCs are of interest because they are potentially smaller, lighter, and more reliable than conventional capacitors and batteries. One issue with using EDLCs in this application is that the piezoelectric voltage output can greatly exceed the EDLC electrolyte breakdown voltage of a single cell, and the oscillation frequency greatly exceeds the frequency response of most commercial EDLCs. We find that electrolyte breakdown is not a serious limitation with transient overvoltage, as electrolyte breakdown is kinetically limited, and further, any breakdown is self-healing. In this study, we report results from capacitors of different sizes and response times, and find that capacitors of similar size store similar quantities of energy, with faster capacitors charging more quickly. (C) 2013 The Electrochemical Society. All rights reserved. C1 [Ervin, M. H.] US Army Res Lab, Adelphi, MD 20783 USA. [Pereira, C. M.] Armament Res, Ctr Dev & Engn, Picatinny Arsenal, NJ 07806 USA. [Miller, J. R.] JME Inc, Beachwood, OH 44122 USA. [Outlaw, R. A.] Coll William & Mary, Williamsburg, VA 23187 USA. [Rastegar, J.; Murray, R. T.] Omnitek Partners LLC, Ronkonkoma, NY 11779 USA. RP Ervin, MH (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. EM matthew.h.ervin.civ@mail.mil NR 4 TC 5 Z9 5 U1 3 U2 20 PU ELECTROCHEMICAL SOC INC PI PENNINGTON PA 65 SOUTH MAIN STREET, PENNINGTON, NJ 08534 USA SN 2162-8769 J9 ECS J SOLID STATE SC JI ECS J. Solid State Sci. Technol. PY 2013 VL 2 IS 10 BP M3135 EP M3139 DI 10.1149/2.019310jss PG 5 WC Materials Science, Multidisciplinary; Physics, Applied SC Materials Science; Physics GA 234ZJ UT WOS:000325683100017 ER PT J AU Keller, SD Zaghloul, AI Shanov, V Schulz, MJ Mast, DB AF Keller, Steven D. Zaghloul, Amir I. Shanov, Vesselin Schulz, Mark J. Mast, David B. TI Design Considerations for a Meshed Carbon Nanotube Thread Patch Antenna SO IEEE ANTENNAS AND WIRELESS PROPAGATION LETTERS LA English DT Article DE Carbon nanotube; meshed antenna; patch antenna ID DIPOLE ANTENNAS; PERFORMANCE; SENSOR AB A meshed carbon nanotube thread patch antenna is proposed and analyzed through full-wave electromagnetic simulation. The effects of thread spacing and of fabricating the feedline and ground-plane layers from meshed thread are explored. Results indicate that minimal impact on antenna radiation efficiency and usable bandwidth is achieved with a thread spacing of d <= lambda/30. A minor center frequency shift and reduction in realized gain and bandwidth occurs when the thread spacing is increased. When the feedline and/or ground plane is constructed from meshed carbon nanotube thread material, the realized gain is significantly reduced. Improvements to carbon nanotube thread conductivity should mitigate this reduction in realized gain. C1 [Keller, Steven D.; Zaghloul, Amir I.] US Army Res Lab, Adelphi, MD 20783 USA. [Shanov, Vesselin; Schulz, Mark J.; Mast, David B.] Univ Cincinnati, Cincinnati, OH 45221 USA. RP Keller, SD (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. EM steven.d.keller8.civ@mail.mil; vesselin.shanov@uc.edu NR 16 TC 2 Z9 2 U1 0 U2 14 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1536-1225 EI 1548-5757 J9 IEEE ANTENN WIREL PR JI IEEE Antennas Wirel. Propag. Lett. PY 2013 VL 12 BP 1192 EP 1195 DI 10.1109/LAWP.2013.2282176 PG 4 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA 234YO UT WOS:000325680600005 ER PT J AU Marlin, B Sohn, HS AF Marlin, Benjamin Sohn, Han-Suk TI MANPOWER MODELING AND SENSITIVITY ANALYSIS FOR AFGHAN EDUCATION POLICY SO INTERNATIONAL JOURNAL OF INDUSTRIAL ENGINEERING-THEORY APPLICATIONS AND PRACTICE LA English DT Article DE Manpower model; sensitivity analysis; Afghanistan; education policy; mixed integer linear program AB This paper provides a demand based balance of flow manpower model premised in mathematical programming to provide insight into the potential futures of the Afghan Education System. Over the previous three decades, torn from multiple wars and an intolerant governing regime, the education system in Afghanistan has been decimated. Over the past 10 years Afghanistan and the international community have dedicated a substantial amount of resources to educate the youth of Afghanistan. By forecasting student demand we are able to determine points of friction in the teacher production policy regarding grade level, gender, and province across a medium-term time horizon. We modify the model to provide sensitivity analysis to inform policies. Examples of such policies are accounting for the length of teacher training programs and encouragement of inter-provincial teacher moves. By later applying a stochastic optimization model potential outcomes regarding changes in teacher retention attributed to policy decisions, incentives to teach, or security concerns are highlighted. This model was developed in support of the validation of a large scale simulation regarding the same subject. C1 [Marlin, Benjamin] United States Army, TRADOC Anal Ctr, TRAC WSMR, White Sands Missile Range, NM 88002 USA. [Marlin, Benjamin; Sohn, Han-Suk] New Mexico State Univ, Dept Ind Engn, Las Cruces, NM 88003 USA. RP Marlin, B (reprint author), United States Army, TRADOC Anal Ctr, TRAC WSMR, White Sands Missile Range, NM 88002 USA. EM benjamin.marlin@us.army.mil; hsohn@nmsu.edu RI Sohn, Hansuk/B-9808-2013 OI Sohn, Hansuk/0000-0002-8126-730X FU United States Army; Afghan Ministry of Education; NATO Training Mission Afghanistan FX This research was partly funded by the United States Army. The support of the Afghan Ministry of Education and NATO Training Mission Afghanistan is gratefully acknowledged. The authors would also like to thank USAID Afghanistan and the U.S. Army analysts for many fruitful discussions and helpful comments during the course of this research. NR 21 TC 1 Z9 1 U1 0 U2 5 PU UNIV CINCINNATI INDUSTRIAL ENGINEERING PI CINCINNATI PA UNIV CINCINNATI, CINCINNATI, OH 45221-0116 USA SN 1943-670X J9 INT J IND ENG-THEORY JI Int. J. Ind. Eng.-Theory Appl. Pract. PY 2013 VL 20 IS 3-4 BP 273 EP 281 PG 9 WC Engineering, Industrial; Engineering, Manufacturing SC Engineering GA 234NM UT WOS:000325651000004 ER PT S AU Conroy, J Humbert, JS AF Conroy, Joseph Humbert, J. Sean BE George, T Islam, MS Dutta, AK TI Structure from Motion in Computationally Constrained Systems SO MICRO- AND NANOTECHNOLOGY SENSORS, SYSTEMS, AND APPLICATIONS V SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Micro- and Nanotechnology Sensors, Systems, and Applications V CY APR 29-MAY 03, 2013 CL Baltimore, MD SP SPIE DE optic flow; optical flow; nonlinear observer; micro air vehicle ID PARAMETERS; OBJECT; EGOMOTION; VISION; IMAGES AB Visual sensing is an attractive method to allow small, palm-sized flying vehicles to navigate complex environments without collisions. Visual processing for unmanned vehicles, however, is typically computationally intense. Insects are able to extract structural information about the environment by appropriate control of self-motion and efficient processing of the visual field. This paper presents a methodology that attempts to capture the insect's ability to do this by constructing a nonlinear observer with provable stability via a Lyapunov analysis. Furthermore, the persistency of excitation condition for the observer illustrates the need for a zig-zagging flight style exhibited by certain insects. C1 [Conroy, Joseph] US Army Res Lab, Adelphi, MD USA. RP Conroy, J (reprint author), US Army Res Lab, Adelphi, MD USA. EM joseph.k.conroy3.civ@mail.mil; humbert@umd.edu NR 32 TC 1 Z9 1 U1 0 U2 4 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9516-7 J9 PROC SPIE PY 2013 VL 8725 AR 87251G DI 10.1117/12.2015296 PG 12 WC Nanoscience & Nanotechnology; Optics; Physics, Applied SC Science & Technology - Other Topics; Optics; Physics GA BHF64 UT WOS:000325263900036 ER PT S AU Edwards, E Ruffin, PB Walker, EA Brantley, CL AF Edwards, Eugene Ruffin, Paul B. Walker, Ebonee A. Brantley, Christina L. BE Varadan, VK TI Development of Sensing Techniques for Weaponry Health Monitoring SO NANOSENSORS, BIOSENSORS, AND INFO-TECH SENSORS AND SYSTEMS 2013 SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Nanosensors, Biosensors, and Info-Tech Sensors and Systems CY MAR 10-14, 2013 CL San Diego, CA SP SPIE, Amer Soc Mech Engineers ID GAS AB Due to the costliness of destructive evaluation methods for assessing the aging and shelf-life of missile and rocket components, the identification of nondestructive evaluation methods has become increasingly important to the Army. Verifying that there is a sufficient concentration of stabilizer is a dependable indicator that the missile's double-based solid propellant is viable. The research outlined in this paper summarizes the Army Aviation and Missile Research, Development, & Engineering Center's (AMRDEC's) comparative use of nanoporous membranes, carbon nanotubes, and optical spectroscopic configured sensing techniques for detecting degradation in rocket motor propellant. The first sensing technique utilizes a gas collecting chamber consisting of nanoporous structures that trap the smaller solid propellant particles for measurement by a gas analysis device. In collaboration with NASA-Ames, sensing methods are developed that utilize functionalized single-walled carbon nanotubes as the key sensing element. The optical spectroscopic sensing method is based on a unique light collecting optical fiber system designed to detect the concentration of the propellant stabilizer. Experimental setups, laboratory results, and overall effectiveness of each technique are presented in this paper. Expectations are for the three sensing mechanisms to provide nondestructive evaluation methods that will offer cost-savings and improved weaponry health monitoring. C1 [Edwards, Eugene; Ruffin, Paul B.; Walker, Ebonee A.; Brantley, Christina L.] US Army Res Dev & Engn Command, Redstone Arsenal, AL 35898 USA. RP Edwards, E (reprint author), US Army Res Dev & Engn Command, Redstone Arsenal, AL 35898 USA. EM paul.ruffin@us.army.mil NR 7 TC 1 Z9 1 U1 0 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9474-0 J9 PROC SPIE PY 2013 VL 8691 AR 869101 DI 10.1117/12.2009126 PG 13 WC Nanoscience & Nanotechnology; Remote Sensing; Optics SC Science & Technology - Other Topics; Remote Sensing; Optics GA BGK10 UT WOS:000323279600001 ER PT J AU Crutcher, SH Osei, A AF Crutcher, Sihon H. Osei, Albert TI The modulated spatial Gausson solution to the Biswas-Milovic equation with log law nonlinearity SO OPTIK LA English DT Article DE Optical solitons; Spatial Gaussons; Log law nonlinearity; Nonlinear Schrodinger equation; Non-Kerr law ID OPTICAL SOLITONS; SCHRODINGERS EQUATION; 1-SOLITON SOLUTION; MEDIA; DISPERSION AB This paper presents the one soliton modulated cosine solution to the Biswas-Milovic equation with log law nonlinearity. The approach is to use the ansatz method to obtain relations for the velocity of the soliton or spatial Gausson with equations for dispersion and the amplitude of the soliton. It turns out that the modulated beam requires an additional periodic relation for the one soliton solution existence. Published by Elsevier GmbH. C1 [Crutcher, Sihon H.] US Army, Res Dev & Engn Command, Redstone Arsenal, AL 35895 USA. [Osei, Albert] Oakwood Univ, Dept Math & Comp Sci, Huntsville, AL 35896 USA. RP Crutcher, SH (reprint author), US Army, Res Dev & Engn Command, Bldg 5400, Redstone Arsenal, AL 35895 USA. EM sihon.crutcher@us.army.mil; osei@oakwood.edu NR 25 TC 8 Z9 8 U1 0 U2 4 PU ELSEVIER GMBH, URBAN & FISCHER VERLAG PI JENA PA OFFICE JENA, P O BOX 100537, 07705 JENA, GERMANY SN 0030-4026 J9 OPTIK JI Optik PY 2013 VL 124 IS 20 BP 4678 EP 4681 DI 10.1016/j.ijleo.2013.01.066 PG 4 WC Optics SC Optics GA 231UY UT WOS:000325445100138 ER PT S AU Bradley, T Iyer, S Alston, R Collis, W Lewis, J Cunningham, G Forsythe, E AF Bradley, Tanina Iyer, Shanthi Alston, Robert Collis, Ward Lewis, Jay Cunningham, Garry Forsythe, Eric BE Teherani, FH Look, DC Rogers, DJ TI The effects of deposition conditions and annealing temperature on the performance of gallium tin zinc oxide thin film transistors SO OXIDE-BASED MATERIALS AND DEVICES IV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Oxide-Based Materials and Devices IV CY FEB 03-06, 2013 CL San Francisco, CA SP SPIE DE Gallium tin zinc oxide; thin film transistor; electrical stress; photoexcitation AB In this work the performance of bottom gate thin film transistors (TFTs) with transparent amorphous gallium tin zinc oxide (GSZO) active layers fabricated by radio frequency sputter deposition using a single GSZO target on SiO2/Si wafers will be presented. Trap density and its energetic distribution, and oxygen chemisorption were found to play a critical role in determining the operational characteristics of the device, all of which can be controlled by the oxygen incorporation and substrate temperature during deposition, along with the post-deposition annealing. In addition device instability, with respect to the electrical stress and optical illumination, can be suppressed by suitably tailoring these parameters. TFTs exhibiting a drain current (ID) of 10(-6) A and on/off current ratio (I-on/off) of 106 was achieved. A stable TFT has been achieved under electrical stress for 2% oxygen flow exhibiting.Delta V-T as low as similar to 0.5 V for 3hr stress under a gate bias of 1.2 and 12 V, with good optical stability. C1 [Bradley, Tanina; Iyer, Shanthi; Alston, Robert; Collis, Ward] North Carolina Agr & Tech State Univ, Dept Elect & Comp Engn, Greensboro, NC 27411 USA. [Iyer, Shanthi] North Carolina Agr & Tech State Univ, Dept Nanoengn, Greensboro, NC 27411 USA. [Lewis, Jay; Cunningham, Garry] Ctr Mat & Elect Technol, Res Triangle Inst Int, Res Triangle Pk, NC 27709 USA. [Forsythe, Eric] Army Res Lab, Adelphi, MD 20783 USA. RP Bradley, T (reprint author), North Carolina Agr & Tech State Univ, Dept Elect & Comp Engn, Greensboro, NC 27411 USA. FU Army Research Office [W911NF-10-1-0316] FX This work is supported by the Army Research Office (Grant# W911NF-10-1-0316, technical monitor Michael Gerhold) and Department of Education Title III program. NR 13 TC 2 Z9 2 U1 0 U2 7 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9395-8 J9 PROC SPIE PY 2013 VL 8626 AR 862615 DI 10.1117/12.2013277 PG 10 WC Materials Science, Multidisciplinary; Optics SC Materials Science; Optics GA BHG44 UT WOS:000325342500028 ER PT S AU Gupta, N AF Gupta, Neelam BE Buford, JA Murrer, RL Ballard, GH TI Characterization of SWIR Hyperspectral Imager with a Multispectral Polarized Scene Projector SO TECHNOLOGIES FOR SYNTHETIC ENVIRONMENTS: HARDWARE-IN-THE-LOOP XVIII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Technologies for Synthetic Environments - Hardware-in-the-Loop XVIII CY MAY 02, 2013 CL Baltimore, MD SP SPIE DE Scene projector; multispectral; Stokes polarization; SWIR; liquid crystal tunable filter; LCTF; liquid crystal on silicon; LCoS; spatial light modulator; SLM; hyperspectral; imager; linear polarization; acousto-optic tunable filter; AOTF AB Recently, the US Army developed a prototype shortwave infrared (SWIR) multispectral polarized scene projector (MPSP) system. This system is capable of projecting single spectral images as well as videos with full polarization content from 850 to 1650 nm with variable spectral bandwidth. The bandwidth can vary between 12 and 100 nm. A multistage liquid crystal tunable filter is used to tune the wavelength of light with desired bandwidth and three reflective 512x512 liquid crystal on silicon (LCoS) spatial light modulators (SLMs) with 37.5 mu m pixel pitch are used to project an image with all Stokes parameters. This scene projector is intended to characterize hardware-in-the loop spectral and polarization performance of spectropolarimetric imagers operating in the SWIR region. We used this projector to characterize a SWIR hyperspectral imager with a single polarization based on an acousto-optic tunable filter (AOTF). Here, we will briefly describe the scene projector and the hyperspectral imager, discuss the experimental setup and present the results of our characterization. C1 US Army Res Lab, Adelphi, MD 20783 USA. RP Gupta, N (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 3 TC 0 Z9 0 U1 1 U2 6 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9498-6 J9 PROC SPIE PY 2013 VL 8707 AR 870706 DI 10.1117/12.2014325 PG 9 WC Optics; Imaging Science & Photographic Technology SC Optics; Imaging Science & Photographic Technology GA BHG97 UT WOS:000325393300003 ER PT J AU Zarogoulidis, P Kioumis, I Porpodis, K Spyratos, D Tsakiridis, K Huang, HD Li, Q Turner, JF Browning, R Hohenforst-Schmidt, W Zarogoulidis, K AF Zarogoulidis, Paul Kioumis, Ioannis Porpodis, Konstantinos Spyratos, Dionysios Tsakiridis, Kosmas Huang, Haidong Li, Qiang Turner, J. Francis Browning, Robert Hohenforst-Schmidt, Wolfgang Zarogoulidis, Konstantinos TI Clinical experimentation with aerosol antibiotics: current and future methods of administration SO DRUG DESIGN DEVELOPMENT AND THERAPY LA English DT Review DE antibiotics; aerosol; nebulizers ID CYSTIC-FIBROSIS PATIENTS; PSEUDOMONAS-AERUGINOSA INFECTION; INHALED AZTREONAM LYSINE; VIBRATING MESH NEBULIZER; INHALATION SOLUTION AZLI; EPITHELIAL LINING FLUID; PULMONARY DRUG-DELIVERY; LONG-TERM BENEFITS; CELL LUNG-CANCER; ALVEOLAR MACROPHAGES AB Currently almost all antibiotics are administered by the intravenous route. Since several systems and situations require more efficient methods of administration, investigation and experimentation in drug design has produced local treatment modalities. Administration of antibiotics in aerosol form is one of the treatment methods of increasing interest. As the field of drug nanotechnology grows, new molecules have been produced and combined with aerosol production systems. In the current review, we discuss the efficiency of aerosol antibiotic studies along with aerosol production systems. The different parts of the aerosol antibiotic methodology are presented. Additionally, information regarding the drug molecules used is presented and future applications of this method are discussed. C1 [Zarogoulidis, Paul; Kioumis, Ioannis; Porpodis, Konstantinos; Spyratos, Dionysios; Zarogoulidis, Konstantinos] Aristotle Univ Thessaloniki, Dept Pulm, G Papanikolaou Gen Hosp, GR-54006 Thessaloniki, Greece. [Zarogoulidis, Paul] Univ Duisburg Essen, Univ Hosp, Ruhrlandklinik, Dept Intervent Pneumol,West German Lung Ctr, Essen, Germany. [Tsakiridis, Kosmas] St Luke Private Hosp Hlth Excellence, Dept Cardiothorac Surg, Thessaloniki, Greece. [Huang, Haidong; Li, Qiang] Second Mil Med Univ, Shanghai Hosp, Affiliated Hosp 1, Dept Resp Dis, Shanghai, Peoples R China. [Turner, J. Francis] Univ Nevada, Sch Med, Natl Supercomp Ctr Energy & Environm, Las Vegas, NV 89154 USA. [Browning, Robert] Walter Reed Army Med Ctr, Natl Naval Med Ctr, Bethesda, MD USA. [Hohenforst-Schmidt, Wolfgang] Univ Wurzburg, Reg Clin Coburg, Dept Med 2, Coburg, Germany. RP Zarogoulidis, P (reprint author), Aristotle Univ Thessaloniki, Dept Pulm, G Papanikolaou Gen Hosp, GR-54006 Thessaloniki, Greece. EM pzarog@hotmail.com NR 144 TC 26 Z9 26 U1 1 U2 18 PU DOVE MEDICAL PRESS LTD PI ALBANY PA PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND SN 1177-8881 J9 DRUG DES DEV THER JI Drug Des. Dev. Ther. PY 2013 VL 7 BP 1115 EP 1134 DI 10.2147/DDDT.S51303 PG 20 WC Chemistry, Medicinal; Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA 226UH UT WOS:000325061000001 PM 24115836 ER PT S AU Connelly, BC Metcalfe, GD Shen, HE Wraback, M AF Connelly, Blair C. Metcalfe, Grace D. Shen, Hongen Wraback, Michael BE Andresen, BF Fulop, GF Hanson, CM Norton, PR TI Time-Resolved Photoluminescence Study of Carrier Recombination and Transport in Type-II Superlattice Infrared Detector Materials SO INFRARED TECHNOLOGY AND APPLICATIONS XXXIX SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Infrared Technology and Applications XXXIX CY APR 29-MAY 03, 2013 CL Baltimore, MD SP SPIE DE Time-resolved photoluminescence; minority carrier lifetime; type-II superlattices; recombination mechanisms; infrared; focal plane arrays; Shockley-Read-Hall ID V-SEMICONDUCTORS; LIFETIME AB Time-resolved photoluminescence (TRPL) is used to study the minority carrier lifetime in type-II superlattice (T2SL) infrared detector materials to investigate the recombination mechanisms, trap states and transport properties that currently limit their performance. Measurements of carrier lifetime have shown that InAs/Ga1-xInxSb T2SLs are dominated by non-radiative Shockley-Read-Hall (SRH) recombination, resulting in short minority carrier lifetimes (10's of nanoseconds at 77 K). A trap energy of similar to 60 meV above the valence band is identified in mid-wavelength infrared n-type InAs/Ga1-xInxSb T2SLs, where trap saturation (non-exponential decay) is observed under high injection levels due to a significantly faster hole capture rate than electron capture rate. Lifetime measurements in "Ga-free" InAs/InAs1-xSbx T2SLs exhibit an order-of-magnitude increase in lifetime (100's of nanoseconds at 77 K) with contributions from both radiative and non-radiative recombination. This improvement is attributed to the reduction of non-radiative recombination centers from the superlattice with the elimination of Ga and suggests that the SRH trap(s) limiting the carrier lifetime of InAs/Ga1-xInxSb T2SLs is native to the Ga1-xInxSb layer. Additionally, radiative recombination is observed in an InAs/GaSb T2SL using a sub-bandgap CW laser to saturate the SRH recombination centers, yielding a radiative lifetime of similar to 140 ns at 77 K. Since carrier transport is a concern in Ga-free T2SLs, it is investigated by studying samples grown with and without barriers (to contain injected carriers to the absorber region). It is determined that carrier transport is poor in InAs/InAs1-xSbx T2SLs because negligible differences are observed in the carrier lifetime. C1 [Connelly, Blair C.; Metcalfe, Grace D.; Shen, Hongen; Wraback, Michael] US Army Res Lab, RDRL SEE M, Adelphi, MD 20783 USA. RP Connelly, BC (reprint author), US Army Res Lab, RDRL SEE M, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM blair.connelly.ctr@mail.mil NR 20 TC 3 Z9 3 U1 3 U2 7 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9495-5 J9 PROC SPIE PY 2013 VL 8704 AR 87040V DI 10.1117/12.2016202 PG 9 WC Optics; Physics, Applied SC Optics; Physics GA BHF60 UT WOS:000325262800029 ER PT S AU Montoya, J Melchor, J Spiliotis, P Taplin, L AF Montoya, J. Melchor, J. Spiliotis, P. Taplin, L. BE Andresen, BF Fulop, GF Hanson, CM Norton, PR TI Wide Field-of-View Dual Band Multispectral Muzzle Flash Detection SO INFRARED TECHNOLOGY AND APPLICATIONS XXXIX SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Infrared Technology and Applications XXXIX CY APR 29-MAY 03, 2013 CL Baltimore, MD SP SPIE DE multispectral; muzzle flash; dual band; Hostile Fire Indication AB Sensor technologies are undergoing revolutionary advances, as seen in the rapid growth of multispectral methodologies. Increases in spatial, spectral, and temporal resolution, and in breadth of spectral coverage, render feasible sensors that function with unprecedented performance. A system was developed that addresses many of the key hardware requirements for a practical dual-band multispectral acquisition system, including wide field of view and spectral/temporal shift between dual bands. The system was designed using a novel dichroic beam splitter and dual band-pass filter configuration that creates two side-by-side images of a scene on a single sensor. A high-speed CMOS sensor was used to simultaneously capture data from the entire scene in both spectral bands using a short focal-length lens that provided a wide field-of-view. The beam-splitter components were arranged such that the two images were maintained in optical alignment and real-time intra-band processing could be carried out using only simple arithmetic on the image halves. An experiment related to limitations of the system to address multispectral detection requirements was performed. This characterized the system's low spectral variation across its wide field of view. This paper provides lessons learned on the general limitation of key hardware components required for multispectral muzzle flash detection, using the system as a hardware example combined with simulated multispectral muzzle flash and background signatures. C1 [Montoya, J.; Melchor, J.] Army Res Lab, White Sands Missile Range, NM 88002 USA. RP Montoya, J (reprint author), Army Res Lab, White Sands Missile Range, NM 88002 USA. EM joseph.montoya.civ@mail.mil NR 11 TC 0 Z9 0 U1 0 U2 2 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9495-5 J9 PROC SPIE PY 2013 VL 8704 AR 87040D DI 10.1117/12.2018297 PG 10 WC Optics; Physics, Applied SC Optics; Physics GA BHF60 UT WOS:000325262800011 ER PT J AU Larkin, GB Kurylo, DD AF Larkin, Gabriella Brick Kurylo, Daniel D. TI Perceptual Grouping and High-Order Cognitive Ability SO JOURNAL OF INDIVIDUAL DIFFERENCES LA English DT Article DE speed of processing; individual differences; perceptual organization; Gestalt; intelligence ID INSPECTION TIME; NEURAL EFFICIENCY; INTELLIGENCE; BRAIN; ORGANIZATION; SPEED; PERFORMANCE; NETWORKS; SCALE; TASK AB High-order cognitive functions require the integration of information across functionally related modules. This relationship suggests that cognitive ability is related to the efficiency and processing speed of basic integrative function. In order to examine individual differences for this relationship, we compared standardized tests of intelligence to visual perceptual grouping abilities, which represents a basic process of integration. Sixty participants discriminated perceived grouping of dot patterns based upon similarity in luminance. Psychophysical measurements were made of the functional limits and processing speed of grouping. We assessed cognitive abilities with the Wechsler Abbreviated Scale of Intelligence (WASI) and found that measures of grouping efficiency as well as speed varied considerably across subjects, indicating substantial individual differences at this relatively early level of visual processing. Faster grouping speed was associated with higher scores on all WASI subtests, whereas grouping ability, when not restricted by time, was associated only with the performance IQ components. These results demonstrate an association between a basic integrative function, in which cognitive and motoric factors were minimized, with measures of high-order cognition, which include both verbal and spatial cognitive components. C1 [Larkin, Gabriella Brick] US Army Res Lab, Human Res & Engn Directorate, Picatinny Arsenal, NJ 07806 USA. [Larkin, Gabriella Brick; Kurylo, Daniel D.] CUNY Brooklyn Coll, Dept Psychol, Brooklyn, NY 11210 USA. RP Larkin, GB (reprint author), US Army Res Lab, Human Res & Engn Directorate, Picatinny Arsenal, NJ 07806 USA. EM gabriella.b.larkin.civ@mail.mil NR 32 TC 0 Z9 0 U1 1 U2 5 PU HOGREFE & HUBER PUBLISHERS PI GOTTINGEN PA MERKELSTR 3, D-37085 GOTTINGEN, GERMANY SN 1614-0001 EI 2151-2299 J9 J INDIVID DIFFER JI J. Individ. Differ. PY 2013 VL 34 IS 3 BP 153 EP 158 DI 10.1027/1614-0001/a000110 PG 6 WC Psychology, Social SC Psychology GA 225KN UT WOS:000324961900004 ER PT J AU Sadler, JM Nguyen, APT Toulan, FR Szabo, JP Palmese, GR Scheck, C Lutgen, S La Scala, JJ AF Sadler, Joshua M. Nguyen, Anh-Phuong T. Toulan, Faye R. Szabo, Jeffrey P. Palmese, Giuseppe R. Scheck, Caroline Lutgen, Steve La Scala, John J. TI Isosorbide-methacrylate as a bio-based low viscosity resin for high performance thermosetting applications SO JOURNAL OF MATERIALS CHEMISTRY A LA English DT Article ID VINYL-ESTER RESINS; INFRARED SPECTROSCOPY; MECHANICAL-PROPERTIES; POLYMER NETWORKS; ACID; TEMPERATURE; POLYESTERS; MONOMERS AB In recent years, the bio-refining industry has developed a number of cyclic molecules with unique attributes derived from renewable carbohydrate feedstocks. Isosorbide is one such compound that has a distinctive fused bicyclic ring system that provides a scaffold for the development of novel bio-based resin systems. We synthesized isosorbide-methacrylate (IM) by the direct esterification of isosorbide using highly reactive species such as methacryloyl chloride or methacrylic anhydride and a base catalyst. IM is a low viscosity (157 cP) cross-linking resin that free radically reacts to form a thermoset polymer with extent of cure at 85%. The resulting polymer has a T-g greater than 240 degrees C and main degradation temperature of similar to 400 degrees C. Mechanical test results showed that IM had a modulus of similar to 4 GPa and strength of 85 MPa. These thermal and mechanical properties show that IM has a significantly higher temperature operating window than any known vinyl ester resin and has similar performance to expensive high temperature epoxy resins. As such, this material has good potential for use in composite applications where a moderate to high temperature free radical cured polymer matrix is needed. C1 [Sadler, Joshua M.; Nguyen, Anh-Phuong T.; Toulan, Faye R.; La Scala, John J.] Army Res Lab, RDRL WMM C, Aberdeen Proving Ground, MD 21005 USA. [Szabo, Jeffrey P.] Def R&D Canada Atlantic, Dartmouth, NS, Canada. [Palmese, Giuseppe R.] Drexel Univ, Dept Chem & Biol Engn, Philadelphia, PA 19104 USA. RP Sadler, JM (reprint author), Army Res Lab, RDRL WMM C, 4600 Deer Creek Loop, Aberdeen Proving Ground, MD 21005 USA. EM john.j.lascala.civ@mail.mil FU U.S. Department of Defense, through the Strategic Environmental Research and Development Program [SERDP WP-1758]; Environmental Quality Basic Research Development Program; U.S. Army Research Laboratory; Dynamic Science, Inc (DSI) FX This research was supported by the U.S. Department of Defense, through the Strategic Environmental Research and Development Program (SERDP WP-1758) and the Environmental Quality Basic Research Development Program administered by the Armaments Research and Development Engineering Command. This research was also supported in part by an appointment to the Postgraduate Research Participation Program at the U.S. Army Research Laboratory administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the U.S. Department of Energy and USARL. This research was supported in part by an interagency agreement between Dynamic Science, Inc (DSI) and U.S. Army Research Laboratory. NR 43 TC 16 Z9 16 U1 10 U2 40 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 2050-7488 J9 J MATER CHEM A JI J. Mater. Chem. A PY 2013 VL 1 IS 40 BP 12579 EP 12586 DI 10.1039/c3ta12918g PG 8 WC Chemistry, Physical; Energy & Fuels; Materials Science, Multidisciplinary SC Chemistry; Energy & Fuels; Materials Science GA 231JZ UT WOS:000325414000028 ER PT J AU Crutcher, SH Osei, AJ Biswas, A AF Crutcher, Sihon H. Osei, Albert J. Biswas, Anjan TI Wobbling phenomena with logarithmic law nonlinear Schrodinger equations for incoherent spatial Gaussons SO OPTIK LA English DT Article DE Optical spatial soliton; Equivalent particle theory; Nonlinear Schrodinger equation; Swing effect; Logarithmic law nonlinearity ID OPTICAL SOLITONS; 1-SOLITON SOLUTION; WAVE-GUIDE; MEDIA AB We apply the equivalence particle principle to several nonlinear Schrodinger equations (NLSEs) that model the propagation of a spatial beam with logarithmic law nonlinearity. Using this principle, expressions for acceleration, spatial frequency, spatial period and other variables for a spatial soliton can be derived from the solution of the homogenous NLSE with logarithmic law nonlinearity. These results agree well with numerical simulations of the perturbed NLSE. We show that if the expression of the acceleration is bounded this means the spatial soliton propagates with a swing effect. Published by Elsevier GmbH. C1 [Crutcher, Sihon H.] US Army Res Dev & Engn Command, WDID Elect & Comp Technol Funct, Redstone Arsenal, AL 35898 USA. [Osei, Albert J.] Oakwood Univ, Dept Math & Comp Sci, Huntsville, AL 35896 USA. [Biswas, Anjan] Delaware State Univ, Dept Math, Dover, DE 19901 USA. RP Crutcher, SH (reprint author), US Army Res Dev & Engn Command, WDID Elect & Comp Technol Funct, Redstone Arsenal, AL 35898 USA. EM sihon.crutcher@us.army.mil RI Biswas, Anjan /D-8500-2012 NR 29 TC 0 Z9 0 U1 1 U2 2 PU ELSEVIER GMBH, URBAN & FISCHER VERLAG PI JENA PA OFFICE JENA, P O BOX 100537, 07705 JENA, GERMANY SN 0030-4026 J9 OPTIK JI Optik PY 2013 VL 124 IS 21 BP 4793 EP 4797 DI 10.1016/j.ijleo.2013.01.081 PG 5 WC Optics SC Optics GA 229AC UT WOS:000325233200024 ER PT B AU Campione, S de Ceglia, D Vincenti, MA Scalora, M Capolino, F AF Campione, Salvatore de Ceglia, Domenico Vincenti, Maria A. Scalora, Michael Capolino, Filippo GP IEEE TI Conditions for Electric Field Enhancement in epsilon-near-zero Slabs under TM-Polarized Oblique Incidence SO 2013 US NATIONAL COMMITTEE OF URSI NATIONAL RADIO SCIENCE MEETING (USNC-URSI NRSM) LA English DT Proceedings Paper CT US-National-Committee-of-URSI National Radio Science Meeting CY JAN 09-12, 2013 CL Boulder, CO SP URSI, US Natl Comm C1 [Campione, Salvatore; Capolino, Filippo] Univ Calif Irvine, Dept Elect Engn & Comp Sci, Irvine, CA 92697 USA. [de Ceglia, Domenico; Vincenti, Maria A.] Aegis Technol Inc, Huntsville, AL 35806 USA. [Scalora, Michael] US Army, Charles M Bowden Res Ctr, RDECOM, Redstone Arsenal, AL 35898 USA. RP Campione, S (reprint author), Univ Calif Irvine, Dept Elect Engn & Comp Sci, Irvine, CA 92697 USA. RI Campione, Salvatore/A-2349-2015 OI Campione, Salvatore/0000-0003-4655-5485 NR 0 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-4778-5; 978-1-4673-4776-1 PY 2013 PG 1 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BGZ24 UT WOS:000324678400028 ER PT B AU Dietlein, CR Qiu, JX AF Dietlein, Charles R. Qiu, Joe X. GP IEEE TI Kilometer-range communications link in the 220 GHz atmospheric window using continuous phase modulation SO 2013 US NATIONAL COMMITTEE OF URSI NATIONAL RADIO SCIENCE MEETING (USNC-URSI NRSM) LA English DT Proceedings Paper CT US-National-Committee-of-URSI National Radio Science Meeting CY JAN 09-12, 2013 CL Boulder, CO SP URSI, US Natl Comm C1 [Dietlein, Charles R.; Qiu, Joe X.] US Army Res Lab, Adelphi, MD 20783 USA. RP Dietlein, CR (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. NR 0 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-4778-5; 978-1-4673-4776-1 PY 2013 PG 1 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BGZ24 UT WOS:000324678400106 ER PT J AU Weiss, SJ AF Weiss, Steven J. GP IEEE TI Resonant Patch Antennas on Spherical Ground Planes and the Need for Fractional Order Associated Legendre Functions SO 2013 US NATIONAL COMMITTEE OF URSI NATIONAL RADIO SCIENCE MEETING (USNC-URSI NRSM) LA English DT Proceedings Paper CT US-National-Committee-of-URSI National Radio Science Meeting CY JAN 09-12, 2013 CL Boulder, CO SP URSI, US Natl Comm C1 US Army Res Lab, Adelphi, MD 20783 USA. RP Weiss, SJ (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. NR 0 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-4778-5 PY 2013 PG 1 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BGZ24 UT WOS:000324678400010 ER PT J AU Zaghloul, AI AF Zaghloul, Amir I. GP IEEE TI Active Reflection Phase Surfaces for Cognitive Radar SO 2013 US NATIONAL COMMITTEE OF URSI NATIONAL RADIO SCIENCE MEETING (USNC-URSI NRSM) LA English DT Proceedings Paper CT US-National-Committee-of-URSI National Radio Science Meeting CY JAN 09-12, 2013 CL Boulder, CO SP URSI, US Natl Comm C1 US Army, Res Lab, Adelphi, MD 20783 USA. RP Zaghloul, AI (reprint author), US Army, Res Lab, Adelphi, MD 20783 USA. EM amir.zaghloul.civ@mail.mil NR 0 TC 0 Z9 0 U1 1 U2 3 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-4778-5 PY 2013 PG 1 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BGZ24 UT WOS:000324678400142 ER PT S AU Ettienne-Modeste, GA AF Ettienne-Modeste, G. A. BE Jung, R McGoron, AJ Riera, J TI Micro- and nano-mechanical properties of a CoCrMo medical implant alloy and the carbide-CoCrMo surfaces SO 29TH SOUTHERN BIOMEDICAL ENGINEERING CONFERENCE (SBEC 2013) SE Proceedings of the Southern Biomedical Engineering Conference LA English DT Proceedings Paper CT 29th Southern Biomedical Engineering Conference (SBEC) CY MAY 03-05, 2013 CL Miami, FL SP IEEE Engn Med & Biol Soc, Tucker Davis Technologies, Univ Miami Biomed Engn, Delsys, Univ Florida, J Crayton Pruitt Family Dept Biomed Engn, IEEE Comp Soc, Florida Int Univ, Coll Engn & Comp, Dept Biomed Engn AB The micro- and nano-mechanical properties of a CoCrMo medical implant alloy and a novel micro-textured carbide-coated CoCrMo alloy (MTCC) surface hardness and roughness were examined using micro- and nano-indentation and surface profilometry. The MTCC surfaces may be a successful alternative bearing material for artificial joints. Understanding the micro- and nano-mechanical, material properties and surface morphology of the MTCC-CoCrMo surface are important for designing wear resistant artificial joints. The micro- textured carbide surfaces were created using a microwave plasma assisted chemical vapor deposition reaction (MPCVD). Micro- and nano-mechanical properties, volumetric wear properties, and surface morphology were measured and used to determine the performance of the conventional CoCrMo alloy and MTCC surfaces (processed for either 2 or 4 hours) in static environments and under severe wear conditions. The hardness and surface parameters of the 4h MTCC surfaces were always greater than the 2h MTCC and CoCrMo alloy surfaces. The mirco- and nano-mechanical properties changed for the CoCrMo alloy, 2h, and 4h MTCC surfaces after, in contrast to before, wear testing. This indicates that the wear mechanisms affect the micro- and nano-mechanical results. Overall, the 4h MTCC surfaces had greater wear resistance than the 2h MTCC or CoCrMo alloy surfaces. C1 [Ettienne-Modeste, G. A.] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Ettienne-Modeste, GA (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. EM geriel.a.ettienne-modeste.ctr@mail.mil NR 7 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1086-4105 BN 978-0-7695-5032-9; 978-1-4799-0624-6 J9 PR SOUTH BIOMED ENG PY 2013 BP 43 EP 44 DI 10.1109/SBEC.2013.30 PG 2 WC Engineering, Biomedical; Engineering, Electrical & Electronic SC Engineering GA BGZ72 UT WOS:000324751700022 ER PT J AU Wongwiwatthananukit, S Zeszotarski, P Thai, A Fuller, R Owusu, Y Tan, C Gomez, L Holuby, S AF Wongwiwatthananukit, Supakit Zeszotarski, Paula Thai, Anthony Fuller, RaeAnne Owusu, Yaw Tan, Candace Gomez, Lara Holuby, Scott TI A Training Program for Pharmacy Students on Providing Diabetes Care SO AMERICAN JOURNAL OF PHARMACEUTICAL EDUCATION LA English DT Article DE diabetes; competence; confidence; attitude; training program ID EDUCATION; CONFIDENCE AB Objective. To compare second- and third-year pharmacy students' competence, attitudes, and self-confidence in providing diabetes care before and after completing a hand-on diabetes training program and to determine if the program had an impact on students' attitude and self-confidence based on their year in the curriculum. Design. The program included classroom lectures and hands-on learning sessions in 5 facets of diabetes care. Pre- and post-test instruments measured students' competence, attitudes, and confidence in diabetes care. Assessment. Students' competence and the mean overall confidence score significantly improved after completing the program, while mean overall attitude score did not. Third-year students had significantly higher confidence scores than did second-year students on both pre- and post-program tests. No significant difference was found for attitude scores between second-and third-year students. Conclusion. The hands-on learning program was an effective approach to training pharmacy students in diabetes care, improving both their competence and confidence. C1 [Wongwiwatthananukit, Supakit; Zeszotarski, Paula; Owusu, Yaw; Tan, Candace; Gomez, Lara] Univ Hawaii, Daniel K Inouye Coll Pharm, Hilo, HI 96720 USA. [Thai, Anthony] Phoenix VA Hlth Care Syst, Phoenix, AZ USA. [Fuller, RaeAnne] Phoenix Indian Med Ctr, Phoenix, AZ USA. [Holuby, Scott] Brooke Army Med Ctr, San Antonio, TX USA. RP Wongwiwatthananukit, S (reprint author), Univ Hawaii, Daniel K Inouye Coll Pharm, Dept Pharm Practice, 34 Rainbow Dr, Hilo, HI 96720 USA. EM supakit@hawaii.edu NR 29 TC 1 Z9 1 U1 1 U2 1 PU AMER ASSOC COLL PHARMACY PI ALEXANDRIA PA 1426 PRINCE STREET, ALEXANDRIA, VA 22314-2815 USA SN 0002-9459 J9 AM J PHARM EDUC JI Am. J. Pharm. Educ. PY 2013 VL 77 IS 7 AR 153 PG 11 WC Education, Scientific Disciplines; Pharmacology & Pharmacy SC Education & Educational Research; Pharmacology & Pharmacy GA 217RZ UT WOS:000324379300018 PM 24052656 ER PT J AU Champagne, VK Gabriel, B Villafuerte, J AF Champagne, V. K. Gabriel, B. Villafuerte, J. BE Song, GL TI Cold spray coatings to improve the corrosion resistance of magnesium (Mg) alloys SO CORROSION PREVENTION OF MAGNESIUM ALLOYS SE Woodhead Publishing in Materials LA English DT Article; Book Chapter DE cold spray; high velocity deposition; supersonic spray; magnesium alloys; powder spray; corrosion protection; commercial equipment ID POWDER PARTICLES; SUBSTRATE; ALUMINUM; DESIGN; NOZZLE AB Magnesium alloys are widely used in aircraft and automotive components because of their inherent light weight compared to other engineering metals. However, premature corrosion is one of the challenges associated with magnesium. In the aerospace industry, many expensive castings cannot be reclaimed adequately because current methods are often inappropriate due to excessive porosity, oxidation and thermal damage. Cold spray is a solid-state coating process that uses a supersonic gas jet to accelerate small particles against a substrate to produce metal bonding by rapid plastic deformation of the impacting particles. Significantly, magnesium components can be repaired, restored and protected by cold spray deposition of pure aluminum which has thus already been specified by some aerospace users as a standard technique for magnesium repair. In this chapter, the state of the art of commercial cold spray technologies for magnesium repair will be discussed, as well as their advantages and limitations compared to traditional thermal processes. C1 [Champagne, V. K.; Gabriel, B.] US Army Res Lab, Aberdeen Proving Ground, MD USA. [Villafuerte, J.] CenterLine Windsor Ltd, Windsor, ON, Canada. RP Villafuerte, J (reprint author), CenterLine Windsor Ltd, Windsor, ON, Canada. EM victor.k.champagne.civ@mail.mil; julio.villafuerte@cntrline.com NR 44 TC 1 Z9 1 U1 0 U2 3 PU WOODHEAD PUBL LTD PI CAMBRIDGE PA ABINGTON HALL ABINGTON, CAMBRIDGE CB1 6AH, CAMBS, ENGLAND BN 978-0-85709-896-2 J9 WOODHEAD PUBL MATER PY 2013 BP 414 EP 445 DI 10.1533/9780857098962.3.414 D2 10.1533/9780857098962 PG 32 WC Metallurgy & Metallurgical Engineering SC Metallurgy & Metallurgical Engineering GA BGR26 UT WOS:000323882300016 ER PT J AU Holder, AA Taylor, P Magnusen, AR Moffett, ET Meyer, K Hong, YL Ramsdale, SE Gordon, M Stubbs, J Seymour, LA Acharya, D Weber, RT Smith, PF Dismukes, GC Ji, P Menocal, L Bai, FW Williams, JL Cropek, DM Jarrett, WL AF Holder, Alvin A. Taylor, Patrick Magnusen, Anthony R. Moffett, Erick T. Meyer, Kyle Hong, Yiling Ramsdale, Stuart E. Gordon, Michelle Stubbs, Javelyn Seymour, Luke A. Acharya, Dhiraj Weber, Ralph T. Smith, Paul F. Dismukes, G. Charles Ji, Ping Menocal, Laura Bai, Fengwei Williams, Jennie L. Cropek, Donald M. Jarrett, William L. TI Preliminary anti-cancer photodynamic therapeutic in vitro studies with mixed-metal binuclear ruthenium(II)-vanadium(IV) complexes SO DALTON TRANSACTIONS LA English DT Article ID HYPERFINE COUPLING-CONSTANTS; ALPHA-AMINO-ACIDS; DNA-CLEAVAGE; OXOVANADIUM(IV) COMPLEXES; RUTHENIUM-PORPHYRIN; VANADIUM COMPLEXES; SCHIFF-BASE; PHENANTHROLINE BASES; MULTIDRUG-RESISTANCE; CANCER STATISTICS AB We report the synthesis and characterisation of mixed-metal binuclear ruthenium(II)-vanadium(IV) complexes, which were used as potential photodynamic therapeutic agents for melanoma cell growth inhibition. The novel complexes, [Ru(pbt)(2)(phen(2)DTT)](PF6)(2)center dot 1.5H(2)O 1 (where phen(2)DTT = 1,4-bis(1,10-phenanthrolin-5-ylsulfanyl)butane-2,3-diol and pbt = 2-(2'-pyridyl)benzothiazole) and [Ru(pbt)(2)(tpphz)](PF6)(2)center dot 3H(2)O 2 (where tpphz = tetrapyrido[3,2-a:2',3'-c:3 '',2 ''-h:2 ''',3 ''';-j]phenazine) were synthesised and characterised. Compound 1 was reacted with [VO(sal-L-tryp)(H2O)] (where sal-L-tryp = N-salicylidene-L-tryptophanate) to produce [Ru(pbt)(2)(phen(2)DTT)VO(sal-L-tryp)](PF6)(2)center dot 5H(2)O 4; while [VO(sal-L-tryp)(H2O)] was reacted with compound 2 to produce [Ru(pbt)(2)(tpphz)VO(sal-L-tryp)](PF6)(2)center dot 6H(2)O 3. All complexes were characterised by elemental analysis, HRMS, ESI MS, UV-visible absorption, ESR spectroscopy, and cyclic voltammetry, where appropriate. In vitro cell toxicity studies (with the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) colorimetric assay) via dark and light reaction conditions were carried out with sodium diaqua-4,4',4 '',4 ''' tetrasulfophthalocyaninecobaltate(II) (Na-4[Co(tspc)(H2O)(2)]), [VO(sal-L-tryp)(phen)]center dot H2O, and the chloride salts of complexes 3 and 4. Such studies involved A431, human epidermoid carcinoma cells; human amelanotic malignant melanoma cells; and HFF, non-cancerous human skin fibroblast cells. Both chloride salts of complexes 3 and 4 were found to be more toxic to melanoma cells than to non-cancerous fibroblast cells, and preferentially led to apoptosis of the melanoma cells over non-cancerous skin cells. The anti-cancer property of the chloride salts of complexes 3 and 4 was further enhanced when treated cells were exposed to light, while no such effect was observed on non-cancerous skin fibroblast cells. ESR and V-51 NMR spectroscopic studies were also used to assess the stability of the chloride salts of complexes 3 and 4 in aqueous media at pH 7.19. This research illustrates the potential for using mixed-metal binuclear ruthenium(II)-vanadium(IV) complexes to fight skin cancer. C1 [Holder, Alvin A.; Taylor, Patrick; Magnusen, Anthony R.; Moffett, Erick T.; Ramsdale, Stuart E.; Gordon, Michelle; Stubbs, Javelyn; Seymour, Luke A.] Univ So Mississippi, Dept Chem & Biochem, Hattiesburg, MS 39406 USA. [Meyer, Kyle; Hong, Yiling] Univ Dayton, Dept Biol, Dayton, OH 45469 USA. [Acharya, Dhiraj; Bai, Fengwei] Univ So Mississippi, Dept Biol Sci, Hattiesburg, MS 39406 USA. [Weber, Ralph T.] EPR Div Bruker BioSpin, Billerica, MA 01821 USA. [Smith, Paul F.; Dismukes, G. Charles] Rutgers State Univ, Dept Chem & Chem Biol, Piscataway, NJ 08854 USA. [Ji, Ping; Menocal, Laura; Williams, Jennie L.] SUNY Stony Brook, Dept Med, Stony Brook, NY 11794 USA. [Cropek, Donald M.] US Army Corps Engineers, Construct Engn Res Lab, Champaign, IL 61822 USA. [Jarrett, William L.] Univ So Mississippi, Sch Polymers & High Performance Mat, Hattiesburg, MS 39406 USA. RP Holder, AA (reprint author), Old Dominion Univ, Dept Chem & Biochem, 4541 Hampton Blvd, Norfolk, VA 23529 USA. EM aholder@odu.edu RI Holder, Alvin/B-6329-2016 OI Holder, Alvin/0000-0001-9618-5297 FU Mississippi INBRE; National Institute of General Medical Sciences of the National Institutes of Health (NIH) [P20 GM103476]; National Science Foundation (NSF) [CHE 0639208]; NSF CRIF:MU Award [0741991]; Aubrey Keith Lucas and Ella Ginn Lucas Endowment for Faculty Excellence Award; ExxonMobil Research and Engineering Company; Alliance for Graduate Education in Mississippi Summer Research Experience for Undergraduates; National Science Foundation [HRD-0450362]; NIH [R01CA140487] FX This research was supported in part by an appointment to the Student Research Participation Program at the U.S. Army Engineer Research and Development Center, Construction Engineering Research Laboratory, administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the U.S. Department of Energy and ERDC-CERL. This work was also supported by the Mississippi INBRE funded by an IDeA award from the National Institute of General Medical Sciences of the National Institutes of Health (NIH) under grant number P20 GM103476. The authors also acknowledge the National Science Foundation (NSF) for funding our ESI and MALDI-ToF mass spectrometers (Grant CHE 0639208). We are also grateful for the use of our Bruker BioSpin EMXmicro ESR spectrometer, which was funded by the NSF CRIF:MU Award # 0741991. AAH appreciates funding from the Aubrey Keith Lucas and Ella Ginn Lucas Endowment for Faculty Excellence Award and ExxonMobil Research and Engineering Company. Funding from the Alliance for Graduate Education in Mississippi Summer Research Experience for Undergraduates (funded by the National Science Foundation, grant number HRD-0450362) for MG and JS is gratefully appreciated. JLW appreciates funding from the NIH, grant number R01CA140487, which helped in gathering data for this research. NR 90 TC 14 Z9 14 U1 1 U2 56 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 1477-9226 J9 DALTON T JI Dalton Trans. PY 2013 VL 42 IS 33 BP 11881 EP 11899 DI 10.1039/c3dt50547b PG 19 WC Chemistry, Inorganic & Nuclear SC Chemistry GA 192YY UT WOS:000322525100015 PM 23783642 ER PT J AU Hall, BG Kirkup, BC Riley, MC Barlow, M AF Hall, Barry G. Kirkup, Benjamin C. Riley, Mathew C. Barlow, Miriam TI Clustering Acinetobacter Strains by Optical Mapping SO GENOME BIOLOGY AND EVOLUTION LA English DT Article DE genome alignment; epidemiology; optical mapping ID PAN-GENOME; STREPTOCOCCUS-PNEUMONIAE; MOLECULAR EPIDEMIOLOGY; STAPHYLOCOCCUS-AUREUS; RESOLUTION; SUPRAGENOME; CORE AB Optical mapping is a technique that produces an ordered restriction map of a bacterial or eukaryotic chromosome. We have developed a new method, the BOP method, to compare experimental optical maps with insilico optical maps of complete genomes to infer the presence/absence of short DNA sequences (bops) in each genome. The BOP method, as implemented by the Optical Mapping suite of four programs, circumvents the necessity of whole-genome multiple alignments and permits reliable strain typing and clustering on the basis of optical maps. We have applied the Optical Mapping Suite to 125 strains of Acinetobacter sp., including 11 completely sequenced genomes and 114 Acinetobacter complex from three US military hospitals. We found that optical mapping completely resolves all 125 strains. Signal to noise analysis showed that when the 125 strains were considered together almost 1/3 of the experimental fragments were misidentified. We found that the set of 125 genomes could be divided into three clusters, two of which included sequenced genomes. Signal to noise analysis after clustering showed that only 3.5% of the experimental restriction fragments were misidentified. Minimum spanning trees of the two clusters that included sequenced genomes are presented. The programs we have developed provide a more rigorous approach for analyzing optical map data than previously existed. C1 [Hall, Barry G.; Barlow, Miriam] Bellingham Res Inst, Bellingham, WA USA. [Kirkup, Benjamin C.; Riley, Mathew C.] Walter Reed Army Inst Res, Silver Spring, MD USA. [Barlow, Miriam] Univ California, Merced, CA USA. RP Barlow, M (reprint author), Bellingham Res Inst, Bellingham, WA USA. EM miriam.barlow@gmail.com RI Kirkup, Benjamin/C-3610-2009 OI Kirkup, Benjamin/0000-0002-8722-6218 FU Institute of General Medical Sciences of the National Institutes of Health [1R15GM090164-01A1]; Department of Defense; Department of the Army FX This work was supported by grant number 1R15GM090164-01A1 from the Institute of General Medical Sciences of the National Institutes of Health to M. B. and by the Department of Defense and the Department of the Army to M. C. R. and B. C. K. Material has been reviewed by the Walter Reed Army Institute of Research. NR 18 TC 2 Z9 2 U1 0 U2 5 PU OXFORD UNIV PRESS PI OXFORD PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND SN 1759-6653 J9 GENOME BIOL EVOL JI Genome Biol. Evol. PY 2013 VL 5 IS 6 BP 1176 EP 1184 DI 10.1093/gbe/evt085 PG 9 WC Evolutionary Biology; Genetics & Heredity SC Evolutionary Biology; Genetics & Heredity GA 220OM UT WOS:000324594100013 PM 23739739 ER PT J AU Reif, MK Wozencraft, JM Dunkin, LM Sylvester, CS Macon, CL AF Reif, Molly K. Wozencraft, Jennifer M. Dunkin, Lauren M. Sylvester, Charlene S. Macon, Christopher L. TI A review of U.S. Army Corps of Engineers airborne coastal mapping in the Great Lakes SO JOURNAL OF GREAT LAKES RESEARCH LA English DT Review DE Airborne; Coastal; Mapping; Lidar; Hyperspectral ID TOPOGRAPHIC LIDAR DATA; SHORELINE CHANGE; PHRAGMITES-AUSTRALIS; LIGHT DETECTION; INVASIVE PLANT; NORTH-CAROLINA; SANDY BEACHES; WATER LINE; VEGETATION; ACCURACY AB The U.S. Army Corps of Engineers (USACE) Joint Airborne Lidar Bathymetry Technical Center of Expertise (JALBTCX) collected its first airborne coastal mapping data on the Great Lakes in 1995. Since then, the JALBTCX has collected nearly 5 billion elevation and depth measurements and created over 2000 geographic information system (GIS) products for the shorelines of the Great Lakes. With improvements in airborne coastal mapping technology and the introduction of regional management for the USACE, surveys expanded into the regional scale, multi-sensor National Coastal Mapping Program (NCMP). The NCMP was initiated in 2004 to produce recurrent, regional, high-resolution light detection and ranging (lidar) elevation data and hyperspectral and aerial imagery to support regional sediment management, regulatory functions, flood damage reduction, asset management, emergency operations, and environmental stewardship. The JALBTCX is a collaboration among the USACE, the U.S. Naval Oceanographic Office (NAVOCEANO), and the National Oceanic and Atmospheric Administration (NOAA). The partners have worked together on airborne coastal mapping and charting since the late 1980s with the goal of advancing airborne lidar bathymetry and associated technologies. The collaboration has fielded three generations of airborne sensors and has transferred this technology to the commercial sector, supporting an expanding market for bathymetric lidar. The purpose of this paper is to provide an overview of the history of USACE survey efforts in the Great Lakes (1995-2012), an in-depth review of the resulting imagery and lidar data products, and new information product developments and applications to support environmental and coastal engineering throughout the Great Lakes region. Published by Elsevier B.V. on behalf of International Association for Great Lakes Research. C1 [Reif, Molly K.] Joint Airborne Lidar Bathymetry Tech Ctr Expertis, Environm Lab, Engn Res & Dev Ctr, Kiln, MS 39556 USA. [Wozencraft, Jennifer M.; Dunkin, Lauren M.] Joint Airborne Lidar Bathymetry Tech Ctr Expertis, Coastal & Hydraul Lab, Engn Res & Dev Ctr, Kiln, MS 39556 USA. [Sylvester, Charlene S.; Macon, Christopher L.] Joint Airborne Lidar Bathymetry Tech Ctr Expertis, Kiln, MS 39556 USA. RP Reif, MK (reprint author), Joint Airborne Lidar Bathymetry Tech Ctr Expertis, Environm Lab, Engn Res & Dev Ctr, 7225 Stennis Airport Rd,Suite 100, Kiln, MS 39556 USA. EM Molly.k.Reif@usace.army.mil FU U.S. Army Corps of Engineers (USACE) Headquarters FX Financial support provided by the U.S. Army Corps of Engineers (USACE) Headquarters. NR 86 TC 4 Z9 4 U1 3 U2 14 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0380-1330 J9 J GREAT LAKES RES JI J. Gt. Lakes Res. PY 2013 VL 39 SU 1 SI SI BP 194 EP 204 DI 10.1016/j.jglr.2012.11.002 PG 11 WC Environmental Sciences; Limnology; Marine & Freshwater Biology SC Environmental Sciences & Ecology; Marine & Freshwater Biology GA 223WP UT WOS:000324843500020 ER PT J AU Yousef, F Kerfoot, WC Brooks, CN Shuchman, R Sabol, B Graves, M AF Yousef, Foad Kerfoot, W. Charles Brooks, Colin N. Shuchman, Robert Sabol, Bruce Graves, Mark TI Using LiDAR to reconstruct the history of a coastal environment influenced by legacy mining SO JOURNAL OF GREAT LAKES RESEARCH LA English DT Article DE Remote sensing; LiDAR; Coastal erosion; Tailings pile; Nipissing dunes; Lake Superior ID LAKE-SUPERIOR; KEWEENAW CURRENT; SEDIMENT RESUSPENSION; LIGHT DETECTION; RANGING LIDAR; MICHIGAN; PENINSULA; CLIMATE; VEGETATION; TRANSPORT AB LiDAR (light detection and ranging) data can be used to create fine digital elevation and bathymetric models (DEMs). Here we examine natural coastal erosion in Grand Traverse Bay, Michigan, a part of Keweenaw Bay in Lake Superior, and discuss how a variety of geological features (submersed river bed and channels associated with the Houghton Low; Nipissing dunes) interact with long-term sediment accumulation patterns. The geological features also modify migrating tailings from a legacy mining site. The combination of LiDAR derived images and aerial photographs allowed us to reconstruct the historical movement of tailings along the coastline. A total of 22.8 million metric tonnes (Mt) of stamp sand were discharged into the coastal environment off Gay, MI. Over a span of 80 years, beaches to the southwest of Gay have progressively received 7.0 Mt (30.7%) of the mass eroded from the original pile, whereas 11.1 Mt (48.7%) have moved into the bay. The total amount accumulated along the beaches now greatly exceeds the mass remaining on the original tailings pile (3.7 Mt; 16.2%). Bathymetric differences between two LiDAR surveys (2008 and 2010) were also used to estimate the mass, and to track the movement of migrating underwater stamp sand bars. These bars are moving southwesterly towards Buffalo Reef, creating a threat to the lake trout and lake whitefish breeding ground. (C) 2013 International Association for Great Lakes Research. Published by Elsevier B.V. All rights reserved. C1 [Yousef, Foad; Kerfoot, W. Charles] Michigan Technol Univ, Lake Super Ecosyst Res Ctr, Houghton, MI 49931 USA. [Yousef, Foad; Kerfoot, W. Charles] Michigan Technol Univ, Dept Biol Sci, Houghton, MI 49931 USA. [Brooks, Colin N.; Shuchman, Robert] Michigan Technol Univ, Michigan Tech Res Inst, Ann Arbor, MI 48105 USA. [Shuchman, Robert] Michigan Technol Univ, Dept Geol & Min Engn & Sci, Houghton, MI 49931 USA. [Sabol, Bruce; Graves, Mark] US Army Engn Res & Dev Ctr, ERDC Environm Lab, Vicksburg, MS 39180 USA. RP Kerfoot, WC (reprint author), Michigan Technol Univ, Lake Super Ecosyst Res Ctr, Houghton, MI 49931 USA. EM fyousef@mtu.edu; wkerfoot@mtu.edu; cnbrooks@mtu.edu; shuchman@mtu.edu; Bruce.M.Sabol@usace.army.mil; Mark.R.Graves@usace.army.mil FU Army Corps of Engineers ERDC-EL laboratory; National Science Foundation [OCE 97-12872] FX Primary funding came from the Army Corps of Engineers ERDC-EL laboratory and was provided by the System Wide Water Resources Program (Dr. Steve Ashby, program manager) at Vicksburg. Efforts were also aided by a National Science Foundation OCE 97-12872 grant to WCK, and a U.S. Environmental Protection Agency Region V Grant to the Baraga Tribal Council passed through to W.C.K. Support for the CHARTS flight and initial data processing was provided by the Corps National Coastal Mapping Program managed by Dr. Jennifer Wozencraft at the JALBTCX Center. We thank Dave Schwab, NOAA GLERL, Ann Arbor, for the assistance on the NOAA LiDAR series overflight and coastal forecast information. We also thank Esteban Chiriboga, and especially Hans Biberhofer for sharing details of the National Water Research Institute and Great Lakes Indian Fish and Wildlife Commission sonar mapping and sediment sampling efforts in Grand Traverse Bay. We also want to recognize the data processing support provided by Michael Sayers and Nathaniel Jessee at MTRI. Lucille Zelazny aided preparation of figures. NR 59 TC 4 Z9 5 U1 5 U2 21 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0380-1330 J9 J GREAT LAKES RES JI J. Gt. Lakes Res. PY 2013 VL 39 SU 1 SI SI BP 205 EP 216 DI 10.1016/j.jglr.2013.01.003 PG 12 WC Environmental Sciences; Limnology; Marine & Freshwater Biology SC Environmental Sciences & Ecology; Marine & Freshwater Biology GA 223WP UT WOS:000324843500021 ER PT J AU Mantena, PR Tadepalli, T Pramanik, B Boddu, VM Brenner, MW Stephenson, LD Kumar, A AF Mantena, P. Raju Tadepalli, Tezeswi Pramanik, Brahmananda Boddu, Veera M. Brenner, Matthew W. Stephenson, L. David Kumar, Ashok TI Energy Dissipation and the High-Strain Rate Dynamic Response of Vertically Aligned Carbon Nanotube Ensembles Grown on Silicon Wafer Substrate SO JOURNAL OF NANOMATERIALS LA English DT Article AB The dynamic mechanical behavior and high-strain rate response characteristics of a functionally graded material (FGM) system consisting of vertically aligned carbon nanotube ensembles grown on silicon wafer substrate (VACNT-Si) are presented. Flexural rigidity (storage modulus) and loss factor (damping) were measured with a dynamic mechanical analyzer in an oscillatory three-point bending mode. It was found that the functionally graded VACNT-Si exhibited significantly higher damping without sacrificing flexural rigidity. A Split-Hopkinson pressure bar (SHPB) was used for determining the system response under high-strain rate compressive loading. Combination of a soft and flexible VACNT forest layer over the hard silicon substrate presented novel challenges for SHPB testing. It was observed that VACNT-Si specimens showed a large increase in the specific energy absorption over a pure Si wafer. C1 [Mantena, P. Raju; Tadepalli, Tezeswi; Pramanik, Brahmananda] Univ Mississippi, Dept Mech Engn, University, MS 38677 USA. [Boddu, Veera M.; Brenner, Matthew W.; Stephenson, L. David; Kumar, Ashok] US Army, Engineer Res & Dev Ctr, Construct Engn Res Lab ERDC CERL, Champaign, IL 61821 USA. RP Mantena, PR (reprint author), Univ Mississippi, Dept Mech Engn, University, MS 38677 USA. EM meprm@olemiss.edu FU US Army Engineer Research and Development Center-Construction Engineering Research Laboratory (ERDC-CERL), Champaign, IL, USA [W9132T-12-P0057] FX This research was funded by Grant no. W9132T-12-P0057 from the US Army Engineer Research and Development Center-Construction Engineering Research Laboratory (ERDC-CERL), Champaign, IL, USA. The authors would like to thank Mr. Damian Stoddard and Mr. Kiyun Kim, mechanical engineering graduate students at the University of Mississippi, for their help with the DMA and Hopkinson bar experiments. NR 14 TC 2 Z9 2 U1 2 U2 19 PU HINDAWI PUBLISHING CORPORATION PI NEW YORK PA 410 PARK AVENUE, 15TH FLOOR, #287 PMB, NEW YORK, NY 10022 USA SN 1687-4110 J9 J NANOMATER JI J. Nanomater. PY 2013 AR 259458 DI 10.1155/2013/259458 PG 7 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Science & Technology - Other Topics; Materials Science GA 222QF UT WOS:000324745500001 ER PT J AU Seo, DM Borodin, O Balogh, D O'Connell, M Ly, Q Han, SD Passerini, S Henderson, WA AF Seo, Daniel M. Borodin, Oleg Balogh, Daniel O'Connell, Michael Ly, Quang Han, Sang-Don Passerini, Stefano Henderson, Wesley A. TI Electrolyte Solvation and Ionic Association III. Acetonitrile-Lithium Salt Mixtures-Transport Properties SO JOURNAL OF THE ELECTROCHEMICAL SOCIETY LA English DT Article ID MOLECULAR-DYNAMICS SIMULATIONS; PROTOPHOBIC APROTIC-SOLVENTS; POLARIZABLE FORCE-FIELDS; TRIPLE-ION; ETHYLENE CARBONATE; CONCENTRATION-DEPENDENCE; CONDUCTANCE EQUATION; QUADRUPOLE FORMATION; MODELING VISCOSITY; DIMETHYL CARBONATE AB Asystematic study of electrolytes has been conducted to explore howsolution structure dictates electrolyte properties. Specifically, the transport properties (viscosity, conductivity and molar conductivity) of acetonitrile-lithium salt mixtures, (AN)(n)-LiX, are reported for electrolytes with LiPF6, LiTFSI (i.e., LiN(SO2CF3)(2)), LiClO4, LiBF4 and LiCF3CO2. These salts have widely varying ion solvation/ionic association behavior which is directly reflected in the transport properties of the AN solutions. Information about the solution structure has been utilized, in concert with molecular dynamic (MD) simulations, to provide mechanistic explanations for the variability noted in the transport properties of the electrolyte mixtures. (C) 2013 The Electrochemical Society. All rights reserved. C1 [Seo, Daniel M.; Balogh, Daniel; O'Connell, Michael; Ly, Quang; Han, Sang-Don; Henderson, Wesley A.] N Carolina State Univ, Ion Liquids & Electrolytes Energy Technol ILEET L, Dept Chem & Biomol Engn, Raleigh, NC 27695 USA. [Borodin, Oleg] USA, Electrochem Branch, Sensor & Electron Devices Directorate, Res Lab, Adelphi, MD 20783 USA. [Passerini, Stefano] Univ Munster, Inst Phys Chem, MEET Battery Res Ctr, D-48149 Munster, Germany. RP Seo, DM (reprint author), N Carolina State Univ, Ion Liquids & Electrolytes Energy Technol ILEET L, Dept Chem & Biomol Engn, Raleigh, NC 27695 USA. EM whender@ncsu.edu RI Borodin, Oleg/B-6855-2012; Passerini, Stefano/A-3859-2015 OI Borodin, Oleg/0000-0002-9428-5291; Passerini, Stefano/0000-0002-6606-5304 FU U.S. Department of Energy, Office of Basic Energy Sciences, Division of Materials Sciences and Engineering [DE-SC0002169] FX The authors wish to express their gratitude to the U.S. Department of Energy, Office of Basic Energy Sciences, Division of Materials Sciences and Engineering which supported the experimental portion of this research under Award DE-SC0002169. NR 55 TC 30 Z9 30 U1 1 U2 47 PU ELECTROCHEMICAL SOC INC PI PENNINGTON PA 65 SOUTH MAIN STREET, PENNINGTON, NJ 08534 USA SN 0013-4651 J9 J ELECTROCHEM SOC JI J. Electrochem. Soc. PY 2013 VL 160 IS 8 BP A1061 EP A1070 DI 10.1149/2.018308jes PG 10 WC Electrochemistry; Materials Science, Coatings & Films SC Electrochemistry; Materials Science GA 223MP UT WOS:000324810000008 ER PT J AU McClure, JP Devine, CK Jiang, RZ Chu, D Cuomo, JJ Parsons, GN Fedkiw, PS AF McClure, Joshua P. Devine, Christina K. Jiang, Rongzhong Chu, Deryn Cuomo, Jerome J. Parsons, Gregory N. Fedkiw, Peter S. TI Oxygen Electroreduction on Ti- and Fe-Containing Carbon Fibers SO JOURNAL OF THE ELECTROCHEMICAL SOCIETY LA English DT Article ID ATOMIC LAYER DEPOSITION; ELECTROLYTE FUEL-CELLS; REDUCTION REACTION; CATALYTIC-ACTIVITY; OXIDE; IRON; ELECTROCATALYSTS; CHALLENGES; OXIDATION; GRAPHENE AB A mixture of iron (II) phthalocyanine and polyacrylonitrile (PAN) was electrospun into fibers and pyrolyzed to form Fe-containing carbon fibers (Fe-PAN). Subsequent atomic layer deposition (ALD) coated the fibers with TiOy deposits (TiOy-Fe-PAN). Scanning transmission electron microscopy equipped with energy dispersive spectroscopy (STEM-EDS) detected C, Fe, and Ti across the diameter of the fiber, and X-ray photoelectron spectroscopy (XPS) revealed Fe(III) and CNx species present. After the ALD process, XPS revealed TiOy species on the Fe-PAN fibers, and heat-treating the TiOy-Fe-PAN samples created TiNxOy and TiNx species. Heat-treating Fe-PAN and TiOy-Fe-PAN samples resulted in a slight decrease in the Fe wt.% but affected an increase in the oxygen reduction reaction (ORR) activity in 0.5M H2SO4 at room temperature compared to the samples not heat treated. Moreover, the presence of Ti species decreased the production of H2O2 and increased the mass activity of the ORR on fibers subjected to cyclic potential excursions relative to samples without Ti species. (C) 2013 The Electrochemical Society. All rights reserved. C1 [McClure, Joshua P.; Devine, Christina K.; Parsons, Gregory N.; Fedkiw, Peter S.] N Carolina State Univ, Dept Chem & Biomol Engn, Raleigh, NC 27695 USA. [McClure, Joshua P.; Jiang, Rongzhong; Chu, Deryn] US Army Res Lab, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA. [Cuomo, Jerome J.] N Carolina State Univ, Dept Mat Sci & Engn, Raleigh, NC 27606 USA. RP McClure, JP (reprint author), N Carolina State Univ, Dept Chem & Biomol Engn, Raleigh, NC 27695 USA. EM fedkiw@ncsu.edu RI Parsons, Gregory/O-9762-2014 OI Parsons, Gregory/0000-0002-0048-5859 FU DoD Science, Mathematics and Research for Transformation (SMART) fellowship program FX We would like to thank the DoD Science, Mathematics and Research for Transformation (SMART) fellowship program for providing a fellowship to Joshua McClure. A special thanks to Dr. Cynthia Lundgren for internship support at the U. S. Army Research Lab - Sensors and Electron Devices Directorate. Thanks to NC State's Analytical Instrument Facility for providing FE-SEM and XPS usage. Thanks to group members Dr. Andrew Loebl for electrospinning training, and Dr. Shengyang Huang for insightful discussions. Finally, we acknowledge the Maryland NanoCenter for assistance with STEM-EDS. NR 41 TC 7 Z9 7 U1 4 U2 47 PU ELECTROCHEMICAL SOC INC PI PENNINGTON PA 65 SOUTH MAIN STREET, PENNINGTON, NJ 08534 USA SN 0013-4651 J9 J ELECTROCHEM SOC JI J. Electrochem. Soc. PY 2013 VL 160 IS 8 BP F769 EP F778 DI 10.1149/2.029308jes PG 10 WC Electrochemistry; Materials Science, Coatings & Films SC Electrochemistry; Materials Science GA 223MP UT WOS:000324810000079 ER PT J AU Wang, Y Kozlovskaya, V Arcibal, IG Cropek, DM Kharlampiev, E AF Wang, Yun Kozlovskaya, Veronika Arcibal, Imee G. Cropek, Donald M. Kharlampiev, Eugenia TI Highly swellable ultrathin poly(4-vinylpyridine) multilayer hydrogels with pH-triggered surface wettability SO SOFT MATTER LA English DT Article ID POLYMER THIN-FILMS; POLYELECTROLYTE MULTILAYERS; WEAK POLYELECTROLYTES; AQUEOUS-SOLUTION; CROSS-LINKING; LAYER; CAPSULES; GLUTARALDEHYDE; MICROCAPSULES; BEHAVIOR AB We report on the synthesis of a novel type of ultrathin hydrogel with remarkably high, fast and reversible swelling/shrinkage and sharp surface wettability transitions in response to pH changes. The poly(4-vinylpyridine) (PVP) hydrogels are produced by the selective cross-linking of PVP copolymer layers in PVP/poly(methacrylic acid) (PVP/PMAA) layer-by-layer (LbL) films assembled by a spin-assisted method on surfaces. These multilayer hydrogels exhibit drastic and reversible 10-fold swelling when pH is switched from neutral to acidic. Importantly, hydrogels at pH > 5 collapse to the thickness of dry films, evincing sharp hydrophilic-to-hydrophobic transitions. The swelling amplitude of these multilayer hydrogel coatings is controlled by varying cross-link densities within the hydrogel. Further, the pH-triggered swelling properties of PVP hydrogels are significantly affected by the multilayer assembly method. PVP films produced using the spin-assisted method experienced almost a 4-fold greater swelling enhancement over their conventionally "dipped" counterparts. Finally, PVP hydrogels dehydrated from basic and acidic solutions show drastically different surface morphology and wettability properties. The hydrogel contact angles vary from 70 degrees to 20 degrees for the films dried from neutral and acidic solutions, respectively. Our study provides better understanding of regulated volume and surface wettability transitions in polymer networks which is critical for developing novel materials for a wide variety of applications including sensing, transport regulation, and self-cleaning coatings. C1 [Wang, Yun; Kozlovskaya, Veronika; Kharlampiev, Eugenia] Univ Alabama Birmingham, Dept Chem, Birmingham, AL 35294 USA. [Arcibal, Imee G.; Cropek, Donald M.] US Army, Engineer Res & Dev Ctr, Construct Engn Res Lab, Champaign, IL 61826 USA. RP Kharlampiev, E (reprint author), Univ Alabama Birmingham, Dept Chem, Birmingham, AL 35294 USA. EM ekharlam@uab.edu FU US Army Corps of Engineers (CERL) [W9132T-12-2-0005] FX This work was supported by US Army Corps of Engineers (CERL, W9132T-12-2-0005). Mr William Higgins (UAB) is acknowledged for technical assistance. NR 72 TC 10 Z9 10 U1 7 U2 41 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 1744-683X J9 SOFT MATTER JI Soft Matter PY 2013 VL 9 IS 39 BP 9420 EP 9429 DI 10.1039/c3sm51496j PG 10 WC Chemistry, Physical; Materials Science, Multidisciplinary; Physics, Multidisciplinary; Polymer Science SC Chemistry; Materials Science; Physics; Polymer Science GA 222TT UT WOS:000324755200020 ER PT S AU Bennett, KW Robertson, J AF Bennett, Kelly W. Robertson, James BE Gilbreath, GC Hawley, CT TI Signal and Image Processing Algorithm Performance in a Virtual and Elastic Computing Environment SO ACTIVE AND PASSIVE SIGNATURES IV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Active and Passive Signatures IV CY MAY 01-02, 2013 CL Baltimore, MD SP SPIE DE Signal and Image Processing; Signatures; Cloud Computing; Amazon Web Services; Security; PHP AB The U.S. Army Research Laboratory (ARL) supports the development of classification, detection, tracking, and localization algorithms using multiple sensing modalities including acoustic, seismic, E-field, magnetic field, PIR, and visual and IR imaging. Multimodal sensors collect large amounts of data in support of algorithm development. The resulting large amount of data, and their associated high-performance computing needs, increases and challenges existing computing infrastructures. Purchasing computer power as a commodity using a Cloud service offers low-cost, pay-as-you-go pricing models, scalability, and elasticity that may provide solutions to develop and optimize algorithms without having to procure additional hardware and resources. This paper provides a detailed look at using a commercial cloud service provider, such as Amazon Web Services (AWS), to develop and deploy simple signal and image processing algorithms in a cloud and run the algorithms on a large set of data archived in the ARL Multimodal Signatures Database (MMSDB). Analytical results will provide performance comparisons with existing infrastructure. A discussion on using cloud computing with government data will discuss best security practices that exist within cloud services, such as AWS. C1 [Bennett, Kelly W.] US Army Res Lab, Adelphi, MD 20783 USA. [Robertson, James] Clearhaven Technol LLC, Dallas, TX USA. RP Bennett, KW (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. NR 4 TC 0 Z9 0 U1 0 U2 1 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9525-9 J9 PROC SPIE PY 2013 VL 8734 AR UNSP 87340B DI 10.1117/12.2016941 PG 16 WC Optics; Telecommunications SC Optics; Telecommunications GA BGK58 UT WOS:000323335100008 ER PT S AU Goodin, C Durst, PJ Prevost, ZT Compton, PJ AF Goodin, Christopher Durst, Phillip J. Prevost, Zachary T. Compton, Patrick J. BE Gilbreath, GC Hawley, CT TI A probabilistic model for simulating the effect of airborne dust on ground-based LIDAR SO ACTIVE AND PASSIVE SIGNATURES IV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Active and Passive Signatures IV CY MAY 01-02, 2013 CL Baltimore, MD SP SPIE DE LIDAR; Dust; Optical Depth AB Field and laboratory measurements of Light Detection and Ranging (LIDAR) sensor interactions with dust have been performed for two types of common ground-based LIDAR sensors. A strong correlation (R-2 > 0.95) between the probability for a return from the dust and the optical depth of the dust was found in the analysis. Based on the experimental correlation, a probabilistic model for LIDAR interactions with dust was developed and verified in field experiments. Finally, the model was integrated into a high-fidelity ray-tracing simulation of LIDAR systems C1 [Goodin, Christopher; Durst, Phillip J.] US Army Engineer Res & Dev Ctr, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. [Prevost, Zachary T.] Univ Mississippi, Mississippi State, MS USA. [Compton, Patrick J.] US Air Force Acad, Colorado Springs, CO USA. RP Goodin, C (reprint author), US Army Engineer Res & Dev Ctr, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM christopher.t.goodin@erdc.dren.mil NR 4 TC 0 Z9 0 U1 0 U2 0 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9525-9 J9 PROC SPIE PY 2013 VL 8734 AR UNSP 87340D DI 10.1117/12.2016434 PG 8 WC Optics; Telecommunications SC Optics; Telecommunications GA BGK58 UT WOS:000323335100010 ER PT S AU Tahmoush, D AF Tahmoush, Dave BE Gilbreath, GC Hawley, CT TI Wideband Radar Micro-Doppler Applications SO ACTIVE AND PASSIVE SIGNATURES IV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Active and Passive Signatures IV CY MAY 01-02, 2013 CL Baltimore, MD SP SPIE DE radar; micro-Doppler; wideband ID FEATURE-EXTRACTION; HUMAN GAIT; MODEL AB Wideband radar provides a significant improvement over traditional narrowband radars for micro-Doppler analysis because the high bandwidth can be used to separate many of the signals in range, allowing a simpler decomposition of the micro-Doppler signals. Recent wideband radar work has focused on micro-Doppler, but there is a point where the narrowband approach used to analyze the micro-Doppler signals breaks down. The effect is shown to be independent of frequency, but the error relative to the bandwidth is shown to be inversely proportional to the frequency and proportional to the velocity of the subject. This error can create a smearing effect in the observed Doppler if it is not corrected, leading to reduced signal-to-noise and the appearance of more diffuse targets in Doppler space. In range-space, wideband data can also break the subject into several range bins, affecting the observed signal to noise ratio. The possible applications of wideband micro-Doppler radar are also shown, including the separation of arm movement from human motion which implies that the arms are not encumbered. C1 US Army Res Lab, Adelphi, MD 20783 USA. RP Tahmoush, D (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. NR 28 TC 0 Z9 0 U1 1 U2 4 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9525-9 J9 PROC SPIE PY 2013 VL 8734 AR UNSP 873403 DI 10.1117/12.2015474 PG 7 WC Optics; Telecommunications SC Optics; Telecommunications GA BGK58 UT WOS:000323335100002 ER PT S AU Yoo, JH Murugan, M Wereley, NM AF Yoo, Jin-Hyeong Murugan, Muthuvel Wereley, Norman M. BE Sodano, HA TI Simulation of Adaptive Semi-Active Magnetorheological Seat Damper for Vehicle Occupant Blast Protection SO ACTIVE AND PASSIVE SMART STRUCTURES AND INTEGRATED SYSTEMS 2013 SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Active and Passive Smart Structures and Integrated Systems CY MAR 10-14, 2013 CL San Diego, CA SP SPIE, Amer Soc Mech Engineers DE Lumped-parameter human body model; mine blast; quarter car model; injury criteria; magnetorheological damper AB This study investigates a lumped-parameter human body model which includes lower leg in seated posture within a quarter-car model for blast injury assessment simulation. To simulate the shock acceleration of the vehicle, mine blast analysis was conducted on a generic land vehicle crew compartment (sand box) structure. For the purpose of simulating human body dynamics with non-linear parameters, a physical model of a lumped-parameter human body within a quarter car model was implemented using multi-body dynamic simulation software. For implementing the control scheme, a skyhook algorithm was made to work with the multi-body dynamic model by running a co-simulation with the control scheme software plug-in. The injury criteria and tolerance levels for the biomechanical effects are discussed for each of the identified vulnerable body regions, such as the relative head displacement and the neck bending moment. The desired objective of this analytical model development is to study the performance of adaptive semi-active magnetorheological damper that can be used for vehicle-occupant protection technology enhancements to the seat design in a mine-resistant military vehicle. C1 [Yoo, Jin-Hyeong; Murugan, Muthuvel] US Army Res Lab, Vehicle Technol Directorate, Aberdeen Proving Ground, MD 21005 USA. RP Yoo, JH (reprint author), US Army Res Lab, Vehicle Technol Directorate, Aberdeen Proving Ground, MD 21005 USA. NR 11 TC 0 Z9 0 U1 2 U2 11 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9471-9 J9 PROC SPIE PY 2013 VL 8688 AR UNSP 86881A DI 10.1117/12.2009227 PG 11 WC Energy & Fuels; Optics; Physics, Applied SC Energy & Fuels; Optics; Physics GA BGK03 UT WOS:000323275800038 ER PT S AU Hastings, JS Madrian, BC Skimmyhorn, WL AF Hastings, Justine S. Madrian, Brigitte C. Skimmyhorn, William L. BE Arrow, KJ Bresnahan, TF TI Financial Literacy, Financial Education, and Economic Outcomes SO ANNUAL REVIEW OF ECONOMICS, VOL 5 SE Annual Review of Economics LA English DT Article; Book Chapter DE personal finance; household finance ID HOUSEHOLD FINANCE; SKILL FORMATION; BEHAVIOR; BIAS; TECHNOLOGY; LIQUIDITY; MARKETS; SAVINGS; PRICES AB In this article, we review the literature on financial literacy, financial education, and consumer financial outcomes. We consider how financial literacy is measured in the current literature and examine how well the existing literature addresses whether financial education improves financial literacy or personal financial outcomes. We discuss the extent to which a competitive market provides incentives for firms to educate consumers or to offer products that facilitate informed choice. We review the literature on alternative policies to improve financial outcomes and compare the evidence with that on the efficacy and cost of financial education. Finally, we discuss directions for future research. C1 [Hastings, Justine S.] Brown Univ, Dept Econ, Providence, RI 02912 USA. [Hastings, Justine S.; Madrian, Brigitte C.] Natl Bur Econ Res, Cambridge, MA 02138 USA. [Madrian, Brigitte C.] Harvard Univ, John F Kennedy Sch Govt, Cambridge, MA 02138 USA. [Skimmyhorn, William L.] US Mil Acad, Dept Social Sci, West Point, NY 10996 USA. RP Hastings, JS (reprint author), Brown Univ, Dept Econ, Providence, RI 02912 USA. EM justine_hastings@brown.edu RI Ramalho, Thiago/E-4525-2016 FU NIA NIH HHS [P01 AG005842, R01 AG021650, R01 AG032411]; NICHD NIH HHS [R24 HD041020] NR 102 TC 33 Z9 33 U1 12 U2 66 PU ANNUAL REVIEWS PI PALO ALTO PA 4139 EL CAMINO WAY, PO BOX 10139, PALO ALTO, CA 94303-0897 USA SN 1941-1383 BN 978-0-8243-4605-8 J9 ANNU REV ECON JI Annu. Rev. Econ. PY 2013 VL 5 BP 347 EP 373 DI 10.1146/annurev-economics-082312-125807 PG 27 WC Economics SC Business & Economics GA BGR46 UT WOS:000323894500013 PM 23991248 ER PT S AU Brady, JJ Pellegrino, PM AF Brady, John J. Pellegrino, Paul M. BE Fountain, AW TI Next Generation Hazard Detection via Ultrafast Coherent Anti-Stokes Raman Spectroscopy SO CHEMICAL, BIOLOGICAL, RADIOLOGICAL, NUCLEAR, AND EXPLOSIVES (CBRNE) SENSING XIV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XIV CY APR 30-MAY 03, 2013 CL Baltimore, MD SP SPIE DE Raman scattering; CARS; femtosecond; energetics; explosives; simulants; chemical warfare ID INDUCED BREAKDOWN SPECTROSCOPY; SCATTERING MICROSCOPY; VIBRATIONAL-SPECTRA; EXPLOSIVE RESIDUES; HEAVY-METALS; LASER; LIGHT; FEMTOSECOND; STANDOFF; ACETONE AB Multiplex coherent anti-Stokes Raman spectroscopy (MCARS) is used to detect an explosive precursor material and two chemical warfare simulants. The spectral bandwidth of the femtosecond laser pulse used in these studies is sufficient to coherently and simultaneously drive all the vibrational modes in the molecule of interest. The research performed here demonstrates that MCARS has the capability to detect an explosive precursor (e. g., acetone) and hazardous materials, such as dimethyl methylphosphonate and 2-chloroethyl methyl sulfide (a sarin and a mustard gas chemical warfare simulant, respectively), with high specificity. Evidence shows that MCARS is capable of overcoming common the sensitivity limitations of spontaneous Raman scattering, thus allowing for the detection of the target material in milliseconds with standard USB spectrometers as opposed to seconds with intensified spectrometers. The exponential increase in the number of scattered photons suggests that the MCARS technique may be capable of overcoming range detection challenges common to spontaneous Raman scattering. C1 [Brady, John J.; Pellegrino, Paul M.] US Army Res Lab, Adelphi, MD 20783 USA. RP Pellegrino, PM (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM paul.m.pellegrino.civ@mail.mil NR 42 TC 1 Z9 1 U1 1 U2 10 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9501-3 J9 PROC SPIE PY 2013 VL 8710 AR UNSP 87100Q DI 10.1117/12.2015838 PG 9 WC Optics; Spectroscopy SC Optics; Spectroscopy GA BGM68 UT WOS:000323515900023 ER PT S AU Finch, AS Coppock, M Bickford, JR Conn, MA Proctor, TJ Stratis-Cullum, DN AF Finch, Amethist S. Coppock, Matthew Bickford, Justin R. Conn, Marvin A. Proctor, Thomas J. Stratis-Cullum, Dimitra N. BE Fountain, AW TI Smart phones: platform enabling modular, chemical, biological, and explosives sensing SO CHEMICAL, BIOLOGICAL, RADIOLOGICAL, NUCLEAR, AND EXPLOSIVES (CBRNE) SENSING XIV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XIV CY APR 30-MAY 03, 2013 CL Baltimore, MD SP SPIE DE Smartphone; ubiquitous sensing; explosives sensing; chemical sensing; biological sensing ID OPTOFLUIDICS; AGENTS; SPECTROSCOPY; FUTURE; POINT AB Reliable, robust, and portable technologies are needed for the rapid identification and detection of chemical, biological, and explosive (CBE) materials. A key to addressing the persistent threat to U. S. troops in the current war on terror is the rapid detection and identification of the precursor materials used in development of improvised explosive devices, homemade explosives, and bio-warfare agents. However, a universal methodology for detection and prevention of CBE materials in the use of these devices has proven difficult. Herein, we discuss our efforts towards the development of a modular, robust, inexpensive, pervasive, archival, and compact platform (android based smart phone) enabling the rapid detection of these materials. C1 [Finch, Amethist S.; Coppock, Matthew; Bickford, Justin R.; Conn, Marvin A.; Proctor, Thomas J.; Stratis-Cullum, Dimitra N.] US Army Res Lab, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA. RP Finch, AS (reprint author), US Army Res Lab, Sensors & Electron Devices Directorate, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. RI Stratis-Cullum, Dimitra/F-9363-2013 OI Stratis-Cullum, Dimitra/0000-0002-4832-6945 NR 23 TC 0 Z9 0 U1 0 U2 13 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9501-3 J9 PROC SPIE PY 2013 VL 8710 AR UNSP 87100D DI 10.1117/12.2014759 PG 7 WC Optics; Spectroscopy SC Optics; Spectroscopy GA BGM68 UT WOS:000323515900012 ER PT S AU Jabbour, RE Wright, JD Deshpande, SV Wade, M McCubbin, P Bevilacqua, V AF Jabbour, Rabih E. Wright, James D. Deshpande, Samir V. Wade, Mary McCubbin, Patrick Bevilacqua, Vicky BE Fountain, AW TI Metaproteomics analyses as diagnostic tool for differentiation of Escherichia coli strains in outbreaks SO CHEMICAL, BIOLOGICAL, RADIOLOGICAL, NUCLEAR, AND EXPLOSIVES (CBRNE) SENSING XIV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XIV CY APR 30-MAY 03, 2013 CL Baltimore, MD SP SPIE DE Escherichia coli; Enterohemorrhagic; Enteropathogenic; Enteroaggregative; Detection; Identification; Mass Spectrometry; Data Analysis; and Bioinformatics ID MASS-SPECTROMETRY; GENOME AB The secreted proteins of the enterohemorrhagic and enteropathogenic E. coli (EHEC and EPEC) are the most common cause of hemorrhagic colitis, a bloody diarrhea with EHEC infection, which often can lead to life threatening hemolytic-uremic syndrome (HUS). We are employing a metaproteomic approach as an effective and complimentary technique to the current genomic based approaches. This metaproteomic approach will evaluate the secreted proteins associated with pathogenicity and utilize their signatures as differentiation biomarkers between EHEC and EPEC strains. The result showed that the identified tryptic peptides of the secreted proteins extracted from different EHEC and EPEC growths have difference in their amino acids sequences and could potentially utilized as biomarkers for the studied E. coli strains. Analysis of extract from EHEC O104:H4 resulted in identification of a multidrug efflux protein, which belongs to the family of fusion proteins that are responsible of cell transportation. Experimental peptides identified lies in the region of the HlyD haemolysin secretion protein-D that is responsible for transporting the haemolysin A toxin. Moreover, the taxonomic classification of EHEC O104:H4 showed closest match with E. coli E55989, which is in agreement with genomic sequencing studies that were done extensively on the mentioned strain. The taxonomic results showed strain level classification for the studied strains and distinctive separation among the strains. Comparative proteomic calculations showed separation between EHEC O157:H7 and O104:H4 in replicate samples using cluster analysis. There are no reported studies addressing the characterization of secreted proteins in various enhanced growth media and utilizing them as biomarkers for strain differentiation. The results of FY-2012 are promising to pursue further experimentation to statistically validate the results and to further explore the impact of environmental conditions on the nature of the secreted biomarkers in various E. coli strains that are of public health concerns in various sectors. C1 [Jabbour, Rabih E.; Wright, James D.; Wade, Mary; Bevilacqua, Vicky] US Army Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD 21010 USA. RP Jabbour, RE (reprint author), US Army Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD 21010 USA. NR 12 TC 0 Z9 0 U1 1 U2 5 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9501-3 J9 PROC SPIE PY 2013 VL 8710 AR UNSP 87101A DI 10.1117/12.2016494 PG 10 WC Optics; Spectroscopy SC Optics; Spectroscopy GA BGM68 UT WOS:000323515900039 ER PT J AU Lardon, MT Fitzgerald, MW AF Lardon, Michael T. Fitzgerald, Michael W. BE Baron, DA Reardon, CL Baron, SH TI Performance Enhancement and the Sports Psychiatrist SO CLINICAL SPORTS PSYCHIATRY: AN INTERNATIONAL PERSPECTIVE LA English DT Article; Book Chapter ID HEART-RATE-VARIABILITY; MENTAL PRACTICE; ASSOCIATION; MOTOR C1 [Lardon, Michael T.] Univ Calif San Diego, Dept Psychiat, Sch Med, San Diego, CA 92103 USA. [Fitzgerald, Michael W.] US Army Hlth Ctr, Schofield Barracks, HI USA. RP Lardon, MT (reprint author), Univ Calif San Diego, Dept Psychiat, Sch Med, San Diego, CA 92103 USA. NR 31 TC 1 Z9 1 U1 0 U2 0 PU BLACKWELL SCIENCE PUBL PI OXFORD PA OSNEY MEAD, OXFORD OX2 0EL, ENGLAND BN 978-1-118-40488-1 PY 2013 BP 132 EP 146 D2 10.1002/9781118404904 PG 15 WC Psychology, Clinical; Psychiatry; Sport Sciences SC Psychology; Psychiatry; Sport Sciences GA BGS34 UT WOS:000323967900016 ER PT J AU Annabi, N Selimovic, S Cox, JPA Ribas, J Bakooshli, MA Heintze, D Weiss, AS Cropek, D Khademhosseini, A AF Annabi, Nasim Selimovic, Seila Acevedo Cox, Juan Pablo Ribas, Joao Bakooshli, Mohsen Afshar Heintze, Deborah Weiss, Anthony S. Cropek, Donald Khademhosseini, Ali TI Hydrogel-coated microfluidic channels for cardiomyocyte culture SO LAB ON A CHIP LA English DT Article ID ON-A-CHIP; HYALURONIC-ACID; DRUG DISCOVERY; TISSUE; DEVICES; CELLS; FABRICATION; BIOLOGY AB The research areas of tissue engineering and drug development have displayed increased interest in organ-on-a-chip studies, in which physiologically or pathologically relevant tissues can be engineered to test pharmaceutical candidates. Microfluidic technologies enable the control of the cellular microenvironment for these applications through the topography, size, and elastic properties of the microscale cell culture environment, while delivering nutrients and chemical cues to the cells through continuous media perfusion. Traditional materials used in the fabrication of microfluidic devices, such as poly(dimethylsiloxane) (PDMS), offer high fidelity and high feature resolution, but do not facilitate cell attachment. To overcome this challenge, we have developed a method for coating microfluidic channels inside a closed PDMS device with a cell-compatible hydrogel layer. We have synthesized photocrosslinkable gelatin and tropoelastin-based hydrogel solutions that were used to coat the surfaces under continuous flow inside 50 mm wide, straight microfluidic channels to generate a hydrogel layer on the channel walls. Our observation of primary cardiomyocytes seeded on these hydrogel layers showed preferred attachment as well as higher spontaneous beating rates on tropoelastin coatings compared to gelatin. In addition, cellular attachment, alignment and beating were stronger on 5% (w/v) than on 10% (w/v) hydrogel-coated channels. Our results demonstrate that cardiomyocytes respond favorably to the elastic, soft tropoelastin culture substrates, indicating that tropoelastin-based hydrogels may be a suitable coating choice for some organ-on-a-chip applications. We anticipate that the proposed hydrogel coating method and tropoelastin as a cell culture substrate may be useful for the generation of elastic tissues, e.g. blood vessels, using microfluidic approaches. C1 [Annabi, Nasim; Selimovic, Seila; Ribas, Joao; Bakooshli, Mohsen Afshar; Heintze, Deborah; Khademhosseini, Ali] Harvard Univ, Sch Med, Ctr Biomed Engn, Dept Med,Brigham & Womens Hosp, Cambridge, MA 02139 USA. [Annabi, Nasim; Selimovic, Seila; Ribas, Joao; Bakooshli, Mohsen Afshar; Heintze, Deborah; Khademhosseini, Ali] MIT, Harvard Mit Div Hlth Sci & Technol, Cambridge, MA 02139 USA. [Annabi, Nasim; Khademhosseini, Ali] Harvard Univ, Wyss Inst Biol Inspired Engn, Boston, MA 02115 USA. [Acevedo Cox, Juan Pablo] Univ Andes, Fac Med, Santiago 7620001, Chile. [Acevedo Cox, Juan Pablo] Univ Andes, Fac Engn & Appl Sci, Santiago 7620001, Chile. [Ribas, Joao] Univ Coimbra, PhD Programme Expt Biol & Biomed, CNC Ctr Neurosci & Cell Biol, P-3030789 Coimbra, Portugal. [Ribas, Joao] Univ Coimbra, Inst Interdisciplinary Res IIIUC, P-3030789 Coimbra, Portugal. [Ribas, Joao] Biocant Ctr Innovat Biotechnol, P-3060197 Cantanhede, Portugal. [Heintze, Deborah] Ecole Polytech Fed Lausanne, Inst Bioengn, CH-1015 Lausanne, Switzerland. [Heintze, Deborah] Ecole Polytech Fed Lausanne, Sch Life Sci, CH-1015 Lausanne, Switzerland. [Weiss, Anthony S.] Univ Sydney, Sch Mol Biosci, Sydney, NSW 2006, Australia. [Weiss, Anthony S.] Univ Sydney, Bosch Inst, Sydney, NSW 2006, Australia. [Weiss, Anthony S.] Univ Sydney, Charles Perkins Ctr, Sydney, NSW 2006, Australia. [Cropek, Donald] US Army, Corps Engineers, Construct Engn Res Lab, Champaign, IL 61822 USA. RP Khademhosseini, A (reprint author), Harvard Univ, Sch Med, Ctr Biomed Engn, Dept Med,Brigham & Womens Hosp, Cambridge, MA 02139 USA. EM alik@rics.bwh.harvard.edu RI Khademhosseini, Ali/A-9435-2010; OI Khademhosseini, Ali/0000-0002-2692-1524; Ribas, Joao/0000-0001-5386-3748; Khademhosseini, Ali/0000-0001-6322-8852; WEISS, ANTHONY/0000-0002-8106-4836 FU National Health and Medical Research Council; US Army ORAU Postdoctoral program; National Science Foundation CAREER Award [DMR 0847287]; Office of Naval Research Young National Investigator Award; National Institutes of Health [HL092836, DE019024, EB012597, AR057837, DE021468, HL099073, EB008392]; Institute for Soldier Nanotechnology; Office of Naval Research; US Army Research Office [W911NF-07-D-0004]; Presidential Early Career Award for Scientists and Engineers (PECASE); Portuguese Foundation for Science and Technology (FCT) [SFRH/BD/ 51679/2011]; Australian Research Council; Australian Defense Health Foundation; National Health & Medical Research Council FX N.A. acknowledges the support from the National Health and Medical Research Council. S.S. acknowledges funding from the US Army ORAU Postdoctoral program. A.K. acknowledges funding from the National Science Foundation CAREER Award (DMR 0847287), the Office of Naval Research Young National Investigator Award, the National Institutes of Health (HL092836, DE019024, EB012597, AR057837, DE021468, HL099073, EB008392), the Institute for Soldier Nanotechnology, the Office of Naval Research, the US Army Research Office (contract W911NF-07-D-0004), and the Presidential Early Career Award for Scientists and Engineers (PECASE). J.R. acknowledges the support from the Portuguese Foundation for Science and Technology (FCT; SFRH/BD/ 51679/2011). A.S.W. acknowledges funding from the Australian Research Council, Australian Defense Health Foundation and National Health & Medical Research Council. The authors thank Thomas Ferrante at the Wyss Institute at Harvard University for his technical assistance with confocal microscopy. A.S.W. is the Scientific Founder of Elastagen Pty Ltd. NR 47 TC 32 Z9 32 U1 8 U2 75 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 1473-0197 J9 LAB CHIP JI Lab Chip PY 2013 VL 13 IS 18 BP 3569 EP 3577 DI 10.1039/c3lc50252j PG 9 WC Biochemical Research Methods; Chemistry, Multidisciplinary; Nanoscience & Nanotechnology SC Biochemistry & Molecular Biology; Chemistry; Science & Technology - Other Topics GA 200ZU UT WOS:000323111300012 PM 23728018 ER PT B AU Costley, RD Diaz-Alvarez, H McKenna, MH AF Costley, R. Daniel Diaz-Alvarez, Henry McKenna, Mihan H. GP ASME TI VIBRATIONAL AND ACOUSTICAL ANALYSIS OF TRUSSED RAILROAD BRIDGE UNDER MOVING LOADS SO PROCEEDINGS OF THE ASME NOISE CONTROL AND ACOUSTICS DIVISION CONFERENCE (NCAD 2012) LA English DT Proceedings Paper CT Internoise/ASME 2012 Noise Control and Acoustics Division Conference CY AUG 19-22, 2012 CL New York, NY SP ASME, Noise Control & Acoust Div AB A Finite Element model has been developed for a Pratt truss railroad bridge located at Ft. Leonard Wood, MO. This model was used to investigate the vibration responses of a bridge under vehicle loading. Modeling results have been obtained for a single axle with two wheels traversing the bridge at different speeds. The current model does not include the effects of vehicle suspension. Superposition of multiple axles has been used to represent a locomotive transiting the bridge. The output of the vibration response was used as an input to an acoustic FE model to determine which vibrational modes radiate infrasound. The vibration and acoustic models of the railroad bridge will be reviewed, and results from the analysis will be presented. Measurements from an accelerometer mounted on the bridge agree reasonably well with model results. Infrasound could potentially be used to remotely provide information on the capacity and number of the vehicles traversing the bridge and to monitor the bridge for significant structural damage. C1 [Costley, R. Daniel; Diaz-Alvarez, Henry; McKenna, Mihan H.] US Army Corps Engineers, Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. RP Costley, RD (reprint author), US Army Corps Engineers, Engineer Res & Dev Ctr, 3909 Halls Ferry Rd,CEERD GS S 5014, Vicksburg, MS 39180 USA. EM dan.costley@usace.army.mil; henry.diaz-alvarez@usace.army.mil; mihan.h.mckenna@usace.army.mil NR 12 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-4532-5 PY 2013 BP 617 EP 629 PG 13 WC Acoustics; Engineering, Mechanical SC Acoustics; Engineering GA BGR71 UT WOS:000323912200067 ER PT S AU Damarla, T Mehmood, A Sabatier, JM AF Damarla, Thyagaraju Mehmood, Asif Sabatier, James M. BE Kadar, I TI Seismic signature analysis for discrimination of people from animals SO SIGNAL PROCESSING, SENSOR FUSION, AND TARGET RECOGNITION XXII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Signal Processing, Sensor Fusion, and Target Recognition XXII CY APR 29-MAY 02, 2013 CL Baltimore, MD SP SPIE DE Seismic sensor; classification; non-negative matrix factorization; single channel source separation ID NONNEGATIVE MATRIX FACTORIZATION; SOURCE SEPARATION; ALGORITHMS AB Cadence analysis has been the main focus for discriminating between the seismic signatures of people and animals. However, cadence analysis fails when multiple targets are generating the signatures. We analyze the mechanism of human walking and the signature generated by a human walker, and compare it with the signature generated by a quadruped. We develop Fourier-based analysis to differentiate the human signatures from the animal signatures. We extract a set of basis vectors to represent the human and animal signatures using non-negative matrix factorization, and use them to separate and classify both the targets. Grazing animals such as deer, cows, etc., often produce sporadic signals as they move around from patch to patch of grass and one must characterize them so as to differentiate their signatures from signatures generated by a horse steadily walking along a path. These differences in the signatures are used in developing a robust algorithm to distinguish the signatures of animals from humans. The algorithm is tested on real data collected in a remote area. C1 [Damarla, Thyagaraju] US Army Res Lab, Networked Sensing & Fus Branch, Adelphi, MD USA. [Mehmood, Asif] Air Force Inst Technol, Dayton, OH USA. [Sabatier, James M.] Univ Mississippi, NCPA, Oxford, MS USA. RP Damarla, T (reprint author), US Army Res Lab, Networked Sensing & Fus Branch, Adelphi, MD USA. EM thyagaraju.damarla.civ@mail.mil NR 23 TC 0 Z9 0 U1 0 U2 2 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9536-5 J9 PROC SPIE PY 2013 VL 8745 AR UNSP 874518 DI 10.1117/12.2014956 PG 11 WC Engineering, Electrical & Electronic; Optics; Telecommunications SC Engineering; Optics; Telecommunications GA BGN53 UT WOS:000323570300048 ER PT J AU Grujicic, M Ramaswami, S Snipes, JS Yavari, R Yen, CF Cheeseman, BA AF Grujicic, M. Ramaswami, S. Snipes, J. S. Yavari, R. Yen, C. -F. Cheeseman, B. A. TI Axial-Compressive Behavior, Including Kink-Band Formation and Propagation, of Single p-Phenylene Terephthalamide (PPTA) Fibers SO ADVANCES IN MATERIALS SCIENCE AND ENGINEERING LA English DT Article ID MATERIAL MODEL; ARAMID FIBERS; PERFORMANCE; COMPOSITES; STRENGTH; POLYUREA AB The mechanical response of p-phenylene terephthalamide (PPTA) single fibers when subjected to uniaxial compression is investigated computationally using coarse-grained molecular statics/dynamics methods. In order to construct the coarse-grained PPTA model (specifically, in order to define the nature of the coarse-grained particles/beads and to parameterize various components of the bead/bead force-field functions), the results of an all-atom molecular-level computational investigation are used. In addition, the microstructure/topology of the fiber core, consisting of a number of coaxial crystalline fibrils, is taken into account. Also, following our prior work, various PPTA crystallographic/topological defects are introduced into the model (at concentrations consistent with the prototypical PPTA synthesis/processing conditions). The analysis carried out clearly revealed (a) formation of the kink bands during axial compression; (b) the role of defects in promoting the formation of kink bands; (c) the stimulating effects of some defects on the fiber-fibrillation process; and (d) the detrimental effect of the prior compression, associated with fiber fibrillation, on the residual longitudinal-tensile strength of the PPTA fibers. C1 [Grujicic, M.; Ramaswami, S.; Snipes, J. S.; Yavari, R.] Clemson Univ, Dept Mech Engn, Clemson, SC 29634 USA. [Yen, C. -F.; Cheeseman, B. A.] Army Res Lab, Weap & Mat Res Directorate, Aberdeen, MD 21005 USA. RP Grujicic, M (reprint author), Clemson Univ, Dept Mech Engn, Clemson, SC 29634 USA. EM gmica@clemson.edu FU Army Research Office (ARO) [W911NF-09-1-0513] FX The material presented in this paper is based on work supported by the Army Research Office (ARO) research contract entitled "Multi-length Scale Material Model Development for Armor-grade Composite," Contract no. W911NF-09-1-0513. The authors are indebted to Dr. Larry Russell of ARO for his continuing support and interest in the present work. NR 27 TC 2 Z9 2 U1 3 U2 22 PU HINDAWI PUBLISHING CORPORATION PI NEW YORK PA 410 PARK AVENUE, 15TH FLOOR, #287 PMB, NEW YORK, NY 10022 USA SN 1687-8434 J9 ADV MATER SCI ENG JI Adv. Mater. Sci. Eng. PY 2013 AR 329549 DI 10.1155/2013/329549 PG 15 WC Materials Science, Multidisciplinary SC Materials Science GA 212FE UT WOS:000323967100001 ER PT J AU Rickards, C Kay, V George, M Ryan, K Hinojosa-Laborde, C Convertino, V AF Rickards, C. Kay, V. George, M. Ryan, K. Hinojosa-Laborde, C. Convertino, V. TI Association of cerebral blood flow variability and cerebral tissue oxygenation with tolerance to central hypovolemia SO CEREBROVASCULAR DISEASES LA English DT Meeting Abstract C1 [Rickards, C.; Kay, V.] Univ N Texas, Hlth Sci Ctr, Ft Worth, TX USA. [George, M.] ISS, Champaign, IL USA. [Ryan, K.; Hinojosa-Laborde, C.; Convertino, V.] US Army Inst Surg Res, Ft Sam Houston, TX USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU KARGER PI BASEL PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND SN 1015-9770 J9 CEREBROVASC DIS JI Cerebrovasc. Dis. PY 2013 VL 35 SU 2 BP 17 EP 18 PG 2 WC Clinical Neurology; Peripheral Vascular Disease SC Neurosciences & Neurology; Cardiovascular System & Cardiology GA 211WF UT WOS:000323941700050 ER PT S AU Barrowes, BE Grzegorczyk, TM Shubitidze, F Fernandez, P O'Neill, K AF Barrowes, Benjamin E. Grzegorczyk, Tomasz M. Shubitidze, Fridon Fernandez, Pablo O'Neill, Kevin BE Broach, JT Isaacs, JC TI The Pedemis Instrument: Operation and APG Field Results SO DETECTION AND SENSING OF MINES, EXPLOSIVE OBJECTS, AND OBSCURED TARGETS XVIII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Detection and Sensing of Mines, Explosive Objects, and Obscured Targets XVIII CY APR 29-MAY 02, 2013 CL Baltimore, MD SP SPIE DE EMI; UXO; Pedemis; quasistatic; vector receiver; sensitivity; handheld; discrimination ID MAGNETIC CHARGE MODEL; UNEXPLODED ORDNANCE; DISCRIMINATION; EXCITATION; UXO AB Pedemis (PortablE Decoupled Electromagnetic Induction Sensor) is a time-domain man-portable electromagnetic induction (EMI) instrument with the intended purpose of improving the detection and classification of UneXploded Ordnance (UXO). Pedemis sports nine coplanar transmitters (the Tx assembly) and nine triaxial receivers held in a fixed geometry with respect to each other (the Rx assembly) but with that Rx assembly physically decoupled from the Tx assembly allowing flexible data acquisition modes and deployment options. Such flexibility is expected to be instrumental in non-trivial terrains exhibiting either an abundant vegetation or being highly contaminated by large or dense clutter. Before validating the sensor in such challenging configurations, however, Pedemis was taken to Aberdeen Proving Ground, MD, for its first test site validation. We describe Pedemis, including its operation and data acquisition modes along with our Aberdeen Proving Ground results. C1 [Barrowes, Benjamin E.; Shubitidze, Fridon; Fernandez, Pablo; O'Neill, Kevin] USACE, ERDC, CRREL, Hanover, NH 03755 USA. RP Barrowes, BE (reprint author), USACE, ERDC, CRREL, 72 Lyme Rd, Hanover, NH 03755 USA. EM benjamin.e.barrowes@usace.army.mil NR 37 TC 0 Z9 0 U1 0 U2 2 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9500-6 J9 PROC SPIE PY 2013 VL 8709 AR UNSP 870903 DI 10.1117/12.2014964 PG 11 WC Engineering, Electrical & Electronic; Remote Sensing; Optics SC Engineering; Remote Sensing; Optics GA BGN43 UT WOS:000323561500002 ER PT B AU Gartrell, C Reagan, J Carter, C AF Gartrell, Chad Reagan, Judy Carter, Caleb GP ASME TI MODERNIZING RAIL INSPECTIONS FOR THE US ARMY CORPS OF ENGINEERS SO PROCEEDINGS OF THE ASME RAIL TRANSPORTATION DIVISION FALL CONFERENCE, RTDF 2012 LA English DT Proceedings Paper CT ASME Rail Transportation Division Fall Conference CY OCT 16-18, 2012 CL Omaha, NE SP ASME, Rail Transportat Div AB The U.S. Army Engineer Research and Development Center (ERDC) executes inspection programs as part of the U.S. Army Transportation Infrastructure Program (ATIP). These inspection, monitoring and assessment programs include airfields, bridges, dams, railroads, waterfront facilities and ranges. To date, the process for these inspection programs has been manually intensive, time consuming and difficult to scale. The US Army Corps is bringing digital business and spatial data collection methods to its inspection program for the military's railroad infrastructure. By combining GPS and GIS technologies into a mobile data collection solution, added efficiency and data quality has been brought to the field inspection workflow. This modernization effort also results in streamlined data processing and reporting. These improved processes will lead to higher quality data, better analysis of the new richer data content and better decisions made by the end users and stakeholders. C1 [Gartrell, Chad] US Army COE, Erdc, GSL, APB, Vicksburg, MS USA. RP Gartrell, C (reprint author), US Army COE, Erdc, GSL, APB, Vicksburg, MS USA. NR 3 TC 0 Z9 0 U1 1 U2 2 PU AMER SOC MECHANICAL ENGINEERS PI NEW YORK PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA BN 978-0-7918-4507-3 PY 2013 BP 189 EP 197 PG 9 WC Engineering, Mechanical; Transportation Science & Technology SC Engineering; Transportation GA BGR76 UT WOS:000323917600020 ER PT J AU Kokil, A Chudomel, JM Homnick, PJ Lahti, PM Kumar, J AF Kokil, Akshay Chudomel, J. Matthew Homnick, Paul J. Lahti, Paul M. Kumar, Jayant TI Push-pull triarylamine additives that enhance dye sensitized solar cell performance SO RSC ADVANCES LA English DT Article ID ENERGY RELAY DYES; CHARGE-TRANSFER; TIO2; EFFICIENCY; LIGHT; ELECTROLYTES; POLYMERS; FILMS AB A new strategy was developed for improving basic dye sensitized solar cell (DSSC) performance, using push-pull organic triarylamines with tunable frontier energy levels as additives in the DSSC electron shuttling electrolyte solution. A significant improvement in the device performance was observed and attributed to improved dye regeneration and hole transport. C1 [Kokil, Akshay; Kumar, Jayant] Univ Massachusetts, Ctr Adv Mat, Lowell, MA 01854 USA. [Chudomel, J. Matthew; Homnick, Paul J.; Lahti, Paul M.] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA. [Chudomel, J. Matthew] Army Res Lab, Adelphi Lab Ctr, Adelphi, MD USA. RP Kumar, J (reprint author), Univ Massachusetts, Ctr Adv Mat, 1 Univ Ave, Lowell, MA 01854 USA. EM lahti@chem.umass.edu; jayant_kumar@uml.edu RI Kokil, Akshay/A-6886-2009 OI Kokil, Akshay/0000-0002-8295-2878 FU Polymer-Based Materials for Harvesting Solar Energy, an Energy Frontier Research Center; U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences [DE-SC0001087] FX This material is based upon work supported as part of Polymer-Based Materials for Harvesting Solar Energy, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences under Award Number DE-SC0001087. NR 26 TC 4 Z9 4 U1 0 U2 15 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 2046-2069 J9 RSC ADV JI RSC Adv. PY 2013 VL 3 IS 36 BP 15626 EP 15629 DI 10.1039/c3ra40986d PG 4 WC Chemistry, Multidisciplinary SC Chemistry GA 203DW UT WOS:000323271700018 ER PT S AU Gurram, P Hu, SW Reale, C Chan, A AF Gurram, Prudhvi Hu, Shuowen Reale, Chris Chan, Alex BE Sadjadi, FA Mahalanobis, A TI Unsupervised Pedestrian Detection Using Support Vector Data Description SO AUTOMATIC TARGET RECOGNITION XXIII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Automatic Target Recognition XXIII CY APR 29-30, 2013 CL Baltimore, MD SP SPIE DE Pedestrian detection; anomaly detection; support vector data description; unsupervised learning AB In this paper, an unsupervised pedestrian detection algorithm is proposed. An input image is first divided into overlapping detection windows in a sliding fashion and Histogram of Oriented Gradients (HOG) features are collected over each window using non-overlapping cells. A distance metric is used to determine the distance between histograms of corresponding cells in each detection window and the average pedestrian HOG template (determined a priori). These distances over a group of cells are concatenated to obtain the feature vector pertaining to a block of cells. The feature vectors over overlapping blocks of cells are concatenated to form the distance feature vector of a detection window. Each window provides a data sample and the data samples extracted from the whole image are then modeled as a normalcy class using Support Vector Data Description (SVDD). The benefit of using the state-of-the-art SVDD technique to model the normalcy class is that it can be controlled by setting an upper limit on the permissible outliers during the modeling process. Assuming that most of the image is covered by background, the outliers that are detected during the modeling of the normalcy class can be hypothesized as detection windows that contain pedestrians in them. The detections are obtained at different scales in order to account for the different sizes of pedestrians. The final pedestrian detections are generated by applying non-maximal suppression on all the detections at all scales. The system is tested on the INRIA pedestrian dataset and its performance analyzed with respect to accuracy and detection rate. C1 [Gurram, Prudhvi; Hu, Shuowen; Reale, Chris; Chan, Alex] US Army Res Lab, ATTN RDRL SES E, Adelphi, MD 20783 USA. RP Gurram, P (reprint author), US Army Res Lab, ATTN RDRL SES E, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM pkgurram@gmail.com; shuowen.hu.civ@mail.mil; reale@umd.edu; alex.l.chan.civ@mail.mil NR 11 TC 0 Z9 0 U1 0 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9535-8 J9 PROC SPIE PY 2013 VL 8744 AR UNSP 874405 DI 10.1117/12.2015398 PG 9 WC Engineering, Electrical & Electronic; Optics; Telecommunications SC Engineering; Optics; Telecommunications GA BGN17 UT WOS:000323552300005 ER PT S AU Hester, CF Risko, KKD AF Hester, Charles F. Risko, Kelly K. D. BE Sadjadi, FA Mahalanobis, A TI Target Manifold Formation Using a Quadratic SDF SO AUTOMATIC TARGET RECOGNITION XXIII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Automatic Target Recognition XXIII CY APR 29-30, 2013 CL Baltimore, MD SP SPIE DE Synthetic Discriminate Function; target manifolds; correlation manifold filters AB Synthetic Discriminant Function (SDF) formulation of correlation filters provides constraints for forming target subspaces for a target set. In this paper we extend the SDF formulation to include quadratic constraints and use this solution to form nonlinear manifolds in the target space. The theory for forming these manifolds will be developed and demonstrated with data. C1 [Hester, Charles F.; Risko, Kelly K. D.] US Army Res Dev & Engn Command, Aviat & Missile Res Dev & Engn Ctr, Weap Dev & Integrat Directorate, Redstone Arsenal, AL 35898 USA. RP Hester, CF (reprint author), US Army Res Dev & Engn Command, Aviat & Missile Res Dev & Engn Ctr, Weap Dev & Integrat Directorate, Redstone Arsenal, AL 35898 USA. NR 7 TC 0 Z9 0 U1 0 U2 0 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9535-8 J9 PROC SPIE PY 2013 VL 8744 AR UNSP 87440M DI 10.1117/12.2015403 PG 6 WC Engineering, Electrical & Electronic; Optics; Telecommunications SC Engineering; Optics; Telecommunications GA BGN17 UT WOS:000323552300018 ER PT S AU Haynes, RA Yoo, JH Flatau, AB AF Haynes, Robert A. Yoo, Jin-Hyeong Flatau, Alison B. BE Dhar, NK Balaya, P Dutta, AK TI Performance of a bending mode energy harvester using Fe-Ga alloy (Galfenol) SO ENERGY HARVESTING AND STORAGE: MATERIALS, DEVICES, AND APPLICATIONS IV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Energy Harvesting and Storage - Materials, Devices, and Applications IV CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE Energy harvesting; optimization; magnetostriction AB An energy harvester is proposed consisting of a unimorph where the active layer is a magnetostrictive Iron-Gallium alloy. A theory for predicting the open voltage of the energy harvester in a bending-mode configuration is derived. A constrained optimization is performed using the open voltage as the objective function to identify key geometric and physical parameters that produce the highest root-mean-square voltage. Conclusions about the sensitivity of the voltage to variations in the parameters are also presented. The useful power is calculated, and the effect of changing the pickup-coil configuration is explored. C1 [Haynes, Robert A.; Yoo, Jin-Hyeong] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Haynes, RA (reprint author), US Army Res Lab, 4603 Flare Loop, Aberdeen Proving Ground, MD 21005 USA. EM robert.a.haynes43.civ@mail.mil NR 6 TC 0 Z9 0 U1 0 U2 11 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9519-8 J9 PROC SPIE PY 2013 VL 8728 AR UNSP 87280U DI 10.1117/12.2016424 PG 8 WC Energy & Fuels; Optics SC Energy & Fuels; Optics GA BGM37 UT WOS:000323496900011 ER PT S AU Sablon, K Mitin, V Vagidov, N Sergeev, A AF Sablon, K. Mitin, V. Vagidov, N. Sergeev, A. BE Dhar, NK Balaya, P Dutta, AK TI Solar cell with charged quantum dots: Optimization for high efficiency SO ENERGY HARVESTING AND STORAGE: MATERIALS, DEVICES, AND APPLICATIONS IV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Energy Harvesting and Storage - Materials, Devices, and Applications IV CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE quantum-dot solar cell; potential barriers; photoelectron capture; photovoltaic efficiency ID BUILT-IN CHARGE; TRANSITIONS; PLASMONICS AB Most of investigations of quantum dot photovoltaic devices are aimed at the development of the intermediate band solar cell. To form the intermediate band by quantum dot electron levels, the dots should be placed close to one to another. This leads to strain accumulation and defects, which increase the photocarrier recombination, and recombination losses. To avoid the nanostructuring-induced recombination, we proposed and studied an alternative approach, which is based on the separation of quantum dots (QDs) or QD clusters from the conducting channels by potential barriers created by quantum dots with built-in charge (Q-BIC). Charging of QDs improves the performance of QD solar cells due to the following factors: Negative dot charging increases electron coupling to sub-bandgap photons and provides effective harvesting of IR energy. Because of the strong difference in effective masses of electrons and holes, an electron level spacing in QDs substantially exceeds a level spacing for holes. Therefore, QDs act as deep traps for electrons, but they are shallow traps for holes. Thus, the holes trapped in QDs may be excited by thermal phonons, while excitation of localized QDs electrons requires IR radiation or the interaction with hot electrons. Therefore, n-doping of QD structures is strongly preferable for photovoltaic applications. Charging of QDs is also an effective tool for managing the potential profile at micro-and nanoscales. Filling QDs predominantly from dopants in the QD medium allows one to maintain the macroscale profile analogous to that in the best conventional single-junction solar cells. C1 [Sablon, K.] US Army Res Lab, Adelphi, MD 20783 USA. RP Sablon, K (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. NR 22 TC 1 Z9 1 U1 0 U2 8 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9519-8 J9 PROC SPIE PY 2013 VL 8728 AR UNSP 87280L DI 10.1117/12.2015812 PG 8 WC Energy & Fuels; Optics SC Energy & Fuels; Optics GA BGM37 UT WOS:000323496900006 ER PT S AU Wilson, DK Borden, CT Bettencourt, ES Yamamoto, KK AF Wilson, D. Keith Borden, Christopher T. Bettencourt, Elizabeth S. Yamamoto, Kenneth K. BE Kelmelis, EJ TI Characterization of infrared imaging performance within a general statistical framework for environmental impacts on battlefield signals and sensing SO MODELING AND SIMULATION FOR DEFENSE SYSTEMS AND APPLICATIONS VIII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Modeling and Simulation for Defense Systems and Applications VIII CY APR 30, 2013 CL Baltimore, MD SP SPIE DE signal modeling; infrared imaging; surveillance; environmental effects; mission-planning systems AB The Environmental Awareness for Sensor and Emitter Employment (EASEE) software models the impacts of terrain and weather on a diverse range of battlefield sensing systems. The goal is to provide mission planning tools that realistically capture complex environmental factors impacting sensor performance, yet are simple enough for users with little specialized training. This paper describes incorporation of infrared (IR) modeling into EASEE, and the subsequent challenges of supporting imaging sensors within a framework that had previously evolved primarily for non-imaging sensors, such as acoustic and seismic. The design requires independently interchangeable modules for signature generation, propagation, and signal processing. Sensor performance metrics, such as probability of detection, are characterized statistically rather than through simulation of actual images. Some key enhancements needed to support imaging sensors were: (1) geometric models for targets, (2) packaging of multiple attributes representing target image properties (radiance, projected area, and spatial spectrum), (3) explicitly distinguishing between signals for the background, target of interest, and nuisance targets, and (4) calculation of apparent temperature differences (as opposed to incoherent energy summation). Target signatures are generated using MuSES (Multi-Service Electro-optic Signature), whereas the IR background properties are generated using FASST (Fast All-Season Soil STrength) and numerical weather prediction models. Propagation is handled primarily with MODTRAN (MODerate resolution atmospheric TRANsmission), although simpler models such as a line-of-sight calculation can also be employed. The Johnson criteria were added to the available library of detection algorithms. C1 [Wilson, D. Keith; Yamamoto, Kenneth K.] US Army Engineer Res & Dev Ctr, Hanover, NH 03755 USA. RP Wilson, DK (reprint author), US Army Engineer Res & Dev Ctr, 72 Lyme Rd, Hanover, NH 03755 USA. EM D.Keith.Wilson@usace.army.mil RI Wilson, D. Keith/A-4687-2012 OI Wilson, D. Keith/0000-0002-8020-6871 NR 4 TC 0 Z9 0 U1 0 U2 1 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9543-3 J9 PROC SPIE PY 2013 VL 8752 AR UNSP 87520J DI 10.1117/12.2018246 PG 10 WC Optics; Telecommunications SC Optics; Telecommunications GA BGM85 UT WOS:000323524600015 ER PT S AU Yamamoto, KK Reznicek, NJ Wilson, DK AF Yamamoto, Kenneth K. Reznicek, Nathan J. Wilson, D. Keith BE Kelmelis, EJ TI Integration of radio-frequency transmission and radar in general software for multimodal battlefield signal modeling SO MODELING AND SIMULATION FOR DEFENSE SYSTEMS AND APPLICATIONS VIII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Modeling and Simulation for Defense Systems and Applications VIII CY APR 30, 2013 CL Baltimore, MD SP SPIE DE radio-frequency transmission; radar; surveillance; environmental effects; mission-planning systems AB The Environmental Awareness for Sensor and Emitter Employment (EASEE) software, being developed by the U. S. Army Engineer Research and Development Center (ERDC), provides a general platform for predicting sensor performance and optimizing sensor selection and placement in complex terrain and weather conditions. It incorporates an extensive library of target signatures, signal propagation models, and sensor systems. A flexible object-oriented design supports efficient integration and simulation of diverse signal modalities. This paper describes the integration of modeling capabilities for radio-frequency (RF) transmission and radar systems from the U. S. Navy Electromagnetic Propagation Integrated Resource Environment (EMPIRE), which contains nearly twenty different realistic RF propagation models. The integration utilizes an XML-based interface between EASEE and EMPIRE to set inputs for and run propagation models. To accommodate radars, fundamental improvements to the EASEE software architecture were made to support active-sensing scenarios with forward and backward propagation of the RF signals between the radar and target. Models for reflecting targets were defined to apply a target-specific, directionally dependent reflection coefficient (i.e., scattering cross section) to the incident wavefields. C1 [Yamamoto, Kenneth K.; Reznicek, Nathan J.; Wilson, D. Keith] US Army Engineer Res & Dev Ctr, Hanover, NH 03755 USA. RP Yamamoto, KK (reprint author), US Army Engineer Res & Dev Ctr, 72 Lyme Rd, Hanover, NH 03755 USA. EM Kenneth.K.Yamamoto@usace.army.mil RI Wilson, D. Keith/A-4687-2012 OI Wilson, D. Keith/0000-0002-8020-6871 NR 3 TC 0 Z9 0 U1 0 U2 0 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9543-3 J9 PROC SPIE PY 2013 VL 8752 AR UNSP 875203 DI 10.1117/12.2018182 PG 8 WC Optics; Telecommunications SC Optics; Telecommunications GA BGM85 UT WOS:000323524600002 ER PT S AU Kelley, TD McGhee, SM AF Kelley, T. D. McGhee, S. M. BE Braun, JJ TI Combining Metric Episodes with Semantic Event Concepts within the Symbolic and Sub-symbolic Robotics Intelligence Control System (SS-RICS) SO MULTISENSOR, MULTISOURCE INFORMATION FUSION: ARCHITECTURES, ALGORITHMS, AND APPLICATIONS 2013 SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Multisensor, Multisource Information Fusion - Architectures, Algorithms, and Applications CY APR 30-MAY 01, 2013 CL Baltimore, MD SP SPIE DE Robotics; Episodic Memory; Conceptual Memory ID MEMORY AB This paper describes the ongoing development of a robotic control architecture that inspired by computational cognitive architectures from the discipline of cognitive psychology. The Symbolic and Sub-Symbolic Robotics Intelligence Control System (SS-RICS) combines symbolic and sub-symbolic representations of knowledge into a unified control architecture. The new architecture leverages previous work in cognitive architectures, specifically the development of the Adaptive Character of Thought-Rational (ACT-R) and Soar. This paper details current work on learning from episodes or events. The use of episodic memory as a learning mechanism has, until recently, been largely ignored by computational cognitive architectures. This paper details work on metric level episodic memory streams and methods for translating episodes into abstract schemas. The presentation will include research on learning through novelty and self generated feedback mechanisms for autonomous systems. C1 [Kelley, T. D.] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Kelley, TD (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. NR 8 TC 0 Z9 0 U1 1 U2 2 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9547-1 J9 PROC SPIE PY 2013 VL 8756 AR UNSP 87560L DI 10.1117/12.2019011 PG 7 WC Engineering, Electrical & Electronic; Optics SC Engineering; Optics GA BGN25 UT WOS:000323554800016 ER PT S AU Dogaru, T Liao, DH Le, C AF Dogaru, Traian Liao, DaHan Le, Calvin BE Ranney, KI Doerry, A TI Three-Dimensional Radar Imaging of Buildings Based on Computer Models SO RADAR SENSOR TECHNOLOGY XVII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Radar Sensor Technology XVII CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE Sensing through-the-wall radar; synthetic aperture radar; computational electromagnetics ID SCATTERING AB This paper describes the study of a through-the-wall radar system for three-dimensional (3-D) building imaging, based on computer simulations. Two possible configurations are considered, corresponding to an airborne spotlight and a ground-based strip-map geometry. The paper details all the steps involved in this analysis: creating the computational meshes, calculating the radar signals scattered by the target, forming the radar images, and processing the images for visualization and interpretation. Particular attention is given to the scattering phenomenology and its dependence on the system geometry. The images are created via the backprojection algorithm and further processed using a constant false-alarm rate (CFAR) detector. We discuss methods of 3-D image visualization and interpretation of the results. C1 [Dogaru, Traian; Liao, DaHan; Le, Calvin] US Army Res Lab, Adelphi, MD 20783 USA. RP Dogaru, T (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 16 TC 0 Z9 0 U1 0 U2 2 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9505-1 J9 PROC SPIE PY 2013 VL 8714 AR UNSP 87140L DI 10.1117/12.2016076 PG 12 WC Optics; Telecommunications SC Optics; Telecommunications GA BGN39 UT WOS:000323559400017 ER PT S AU Govoni, MA Silvious, J Clark, J Overman, C AF Govoni, Mark A. Silvious, Jerry Clark, John Overman, Charles BE Ranney, KI Doerry, A TI Initial experimental results using the noise correlation radar SO RADAR SENSOR TECHNOLOGY XVII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Radar Sensor Technology XVII CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE noise correlation radar; advanced pulse compression noise; spectrum; interference ID LINEAR-FM; WAVE-FORM AB Experimental results from recent field testing with the noise correlation radar (NCR) are presented as a proof of concept. In order to understand the effectiveness of the NCR, a pre-determined set of measures is established. We discuss the three experimental configurations used in evaluating the system's range resolution/error, robustness to interference, and secure radio frequency (RF) emission. We show that the advanced pulse compression noise (APCN) radar waveform has low range measurement error, is robust to interference, and is spectrally non-deterministic. In addition, we determine that an improvement in range resolution due to phase modulation is achieved as a function of the random code length rather than the compressed pulse length. C1 [Govoni, Mark A.] US Army CERDEC, Div Radar, Aberdeen Proving Ground, MD 21005 USA. [Silvious, Jerry; Clark, John] U S Army Res Lab, Adelphi, MD 20783 USA. [Overman, Charles] Univ Florida, Gainesville, FL 32611 USA. RP Govoni, MA (reprint author), US Army CERDEC, Div Radar, Aberdeen Proving Ground, MD 21005 USA. NR 6 TC 0 Z9 0 U1 1 U2 1 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9505-1 J9 PROC SPIE PY 2013 VL 8714 AR UNSP 871407 DI 10.1117/12.2016619 PG 15 WC Optics; Telecommunications SC Optics; Telecommunications GA BGN39 UT WOS:000323559400005 ER PT S AU Hedden, AS Wikner, DA Martone, A McNamara, D AF Hedden, Abigail S. Wikner, David A. Martone, Anthony McNamara, David BE Ranney, KI Doerry, A TI Cognitive nonlinear radar test-bed SO RADAR SENSOR TECHNOLOGY XVII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Radar Sensor Technology XVII CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE nonlinear radar; cognitive radar; adaptive radar; spectrum sensing; test-bed AB Providing situational awareness to the warfighter requires radar, communications, and other electronic systems that operate in increasingly cluttered and dynamic electromagnetic environments. There is a growing need for cognitive RF systems that are capable of monitoring, adapting to, and learning from their environments in order to maintain their effectiveness and functionality. Additionally, radar systems are needed that are capable of adapting to an increased number of targets of interest. Cognitive nonlinear radar may offer critical solutions to these growing problems. This work focuses on ongoing efforts at the U.S. Army Research Laboratory (ARL) to develop a cognitive nonlinear radar test-bed. ARL is working toward developing a test-bed that uses spectrum sensing to monitor the RF environment and dynamically change the transmit waveforms to achieve detection of nonlinear targets with high confidence. This work presents the architecture of the test-bed system along with a discussion of its current capabilities and limitations. A brief outlook is presented for the project along with a discussion of a future cognitive nonlinear radar test-bed. C1 [Hedden, Abigail S.; Wikner, David A.; Martone, Anthony; McNamara, David] US Army Res Lab, Adelphi, MD 20783 USA. RP Hedden, AS (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM abigail.s.hedden.civ@mail.mil NR 6 TC 0 Z9 0 U1 0 U2 1 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9505-1 J9 PROC SPIE PY 2013 VL 8714 AR UNSP 87140X DI 10.1117/12.2017861 PG 7 WC Optics; Telecommunications SC Optics; Telecommunications GA BGN39 UT WOS:000323559400029 ER PT S AU Liao, DH AF Liao, DaHan BE Ranney, KI Doerry, A TI Scattering and Imaging of Nonlinearly Loaded Antenna Structures in Half-Space Environments SO RADAR SENSOR TECHNOLOGY XVII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Radar Sensor Technology XVII CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE Computational electromagnetics; harmonic balance; linear and nonlinear electromagnetic scattering; method-of-moments; multistatic radar imaging; radiowave propagation; remote sensing; subspace-based imaging ID MOM-AOM APPROACH; FREQUENCY-DOMAIN; TRANSIENT-RESPONSE; EXTENDED TARGETS; HARMONIC RADAR; WIRE; ALGORITHMS; SYSTEMS; ARRAYS AB The electromagnetic scattering responses of nonlinearly loaded antenna structures excited by single-tone or multi-tone incident fields are considered in the frequency domain by employing a combination of the method-of-moments and a harmonic balance technique. Subsequently, standoff detection and localization of the scatterers in the presence of a half space is demonstrated with a subspace imaging procedure by exploiting the harmonic scattering responses. C1 US Army Res Lab, Adelphi, MD USA. RP Liao, DH (reprint author), US Army Res Lab, Adelphi, MD USA. EM dahan.liao.civ@mail.mil NR 35 TC 0 Z9 0 U1 0 U2 0 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9505-1 J9 PROC SPIE PY 2013 VL 8714 AR UNSP 87140I DI 10.1117/12.2021385 PG 10 WC Optics; Telecommunications SC Optics; Telecommunications GA BGN39 UT WOS:000323559400014 ER PT S AU Liao, DH Dogaru, T AF Liao, DaHan Dogaru, Traian BE Ranney, KI Doerry, A TI Emulation of Forward-Looking Radar Technology for Threat Detection in Rough Terrain Environments: A Scattering and Imaging Study SO RADAR SENSOR TECHNOLOGY XVII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Radar Sensor Technology XVII CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE Computational electromagnetics; finite-difference time-domain method; forward-looking radar; ground surface electromagnetic scattering; landmine detection; multistatic radar imaging; time-reversal imaging ID GROUND-PENETRATING RADAR; MONTE-CARLO SIMULATIONS; FAST MULTIPOLE METHOD; ELECTROMAGNETIC SCATTERING; SURFACE SCATTERING; OBJECT; TARGET; INTERFACE; DIPOLE; SYSTEM AB Large-scale, full-wave modeling of multistatic target imaging in a rough ground environment is described. The emulation methodology employs a parallelized three-dimensional "near-field" finite-difference time-domain algorithm in characterizing the electromagnetic scattering from the ground surface and buried and on-surface targets in the form of landmines and unexploded ordnances; subsequent focusing of the scattered fields into an image is obtained with the time-reversal technique. The emphasis of this study is on investigating the detectability of discrete ground targets in the presence of distributed variable ground clutter as relevant to performance prediction for ultra-wideband forward-looking radar applications. C1 [Liao, DaHan; Dogaru, Traian] US Army Res Lab, Adelphi, MD USA. RP Liao, DH (reprint author), US Army Res Lab, Adelphi, MD USA. EM dahan.liao.civ@mail.mil NR 35 TC 4 Z9 4 U1 0 U2 5 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9505-1 J9 PROC SPIE PY 2013 VL 8714 AR UNSP 87140D DI 10.1117/12.2016392 PG 16 WC Optics; Telecommunications SC Optics; Telecommunications GA BGN39 UT WOS:000323559400010 ER PT S AU Martone, A Ranney, K Hedden, A Mazzaro, G McNamara, D AF Martone, Anthony Ranney, Kenneth Hedden, Abigail Mazzaro, Gregory McNamara, David BE Ranney, KI Doerry, A TI Cognitive Processing for Nonlinear Radar SO RADAR SENSOR TECHNOLOGY XVII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Radar Sensor Technology XVII CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE cognitive radar; radar; cognitive radio; spectrum sensing; nonlinear radar ID WAVE-FORM DESIGN; HARMONIC RADAR; INTERMODULATION DISTORTION; ADAPTIVE RADAR; RADIO; SYSTEMS; SIMULATION; PRODUCTS AB An increasingly cluttered electromagnetic environment (EME) is a growing problem for radar systems. This problem is becoming critical as the available frequency spectrum shrinks due to growing wireless communication device usage and changing regulations. A possible solution to these problems is cognitive radar, where the cognitive radar learns from the environment and intelligently modifies the transmit waveform. In this paper, a cognitive nonlinear radar processing framework is introduced where the main components of this framework consist of spectrum sensing processing, target detection and classification, and decision making. The emphasis of this paper is to introduce a spectrum sensing processing technique that identifies a transmit-receive frequency pair for nonlinear radar. It will be shown that the proposed technique successfully identifies a transmit-receive frequency pair for nonlinear radar from data collected from the EME. C1 [Martone, Anthony; Ranney, Kenneth; Hedden, Abigail; Mazzaro, Gregory; McNamara, David] Army Res Lab, Adelphi, MD 20783 USA. RP Martone, A (reprint author), Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 35 TC 0 Z9 0 U1 1 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9505-1 J9 PROC SPIE PY 2013 VL 8714 AR UNSP 87140H DI 10.1117/12.2018948 PG 10 WC Optics; Telecommunications SC Optics; Telecommunications GA BGN39 UT WOS:000323559400013 ER PT S AU Mazzaro, GJ Martone, AF AF Mazzaro, Gregory J. Martone, Anthony F. BE Ranney, KI Doerry, A TI Multitone Harmonic Radar SO RADAR SENSOR TECHNOLOGY XVII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Radar Sensor Technology XVII CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE multitone; harmonic; radar; detection; discrimination; radio frequency; electronics; nonlinear; response ID INSECT TRACKING; INTERMODULATION; NONLINEARITIES; TAGS AB Nonlinear radar exploits the electronic response from a target whose reflected frequencies are different from those transmitted. Reception of frequencies that are not part of the transmitted probe distinguishes the received signal from a linear return produced by clutter and indicates the presence of electronics. Presented in this paper is a type of nonlinear radar that transmits multiple frequencies and listens for a harmonic of these frequencies as well as other frequencies near that harmonic. A laboratory test-bed has been constructed to demonstrate the multitone radar concept. Measurements of nonlinear responses from RF devices probed by multiple tones are reported. C1 [Mazzaro, Gregory J.; Martone, Anthony F.] US Army Res Lab, Adelphi, MD 20783 USA. RP Mazzaro, GJ (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 32 TC 2 Z9 2 U1 0 U2 2 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9505-1 J9 PROC SPIE PY 2013 VL 8714 AR UNSP 87140E DI 10.1117/12.2014241 PG 7 WC Optics; Telecommunications SC Optics; Telecommunications GA BGN39 UT WOS:000323559400011 ER PT S AU Ojowu, O Wu, Y Li, J Nguyen, L AF Ojowu, Ode, Jr. Wu, Yue Li, Jian Lam Nguyen BE Ranney, KI Doerry, A TI SIRE: A MIMO radar for landmine/IED detection SO RADAR SENSOR TECHNOLOGY XVII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Radar Sensor Technology XVII CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE Synchronous impulse reconstruction (SIRE); MIMO Radar; UWB; RFI Suppression; SAR ID WIDE-BAND RADAR; SUPPRESSION; SYSTEMS; RFI AB Multiple-input multiple-output (MIMO) radar systems have been shown to have significant performance improvements over their single-input multiple-output (SIMO) counterparts. For transmit and receive elements that are collocated, the waveform diversity afforded by this radar is exploited for performance improvements. These improvements include but are not limited to improved target detection, improved parameter identifiability and better resolvability. In this paper, we present the Synchronous Impulse Reconstruction Radar (SIRE) Ultra-wideband (UWB) radar designed by the Army Research Lab (ARL) for landmine and improvised explosive device (IED) detection as a 2 by 16 MIMO radar (with collocated antennas). Its improvement over its SIMO counterpart in terms of beampattern/cross range resolution are discussed and demonstrated using simulated data herein. The limitations of this radar for Radio Frequency Interference (RFI) suppression are also discussed in this paper. A relaxation method (RELAX) combined with averaging of multiple realizations of the measured data is presented for RFI suppression; results show no noticeable target signature distortion after suppression. In this paper, the back-projection (delay and sum) data independent method is used for generating SAR images. A side-lobe minimization technique called recursive side-lobe minimization (RSM) is also discussed for reducing side-lobes in this data independent approach. We introduce a data-dependent sparsity based spectral estimation technique called Sparse Learning via Iterative Minimization (SLIM) as well as a data-dependent CLEAN approach for generating SAR images for the SIRE radar. These data-adaptive techniques show improvement in side-lobe reduction and resolution for simulated data for the SIRE radar. C1 [Ojowu, Ode, Jr.; Wu, Yue; Li, Jian] Univ Florida, Dept Elect Engn, Gainesville, FL 32611 USA. [Lam Nguyen] U S Army Res Lab, Adelphi, MD 20783 USA. RP Li, J (reprint author), Univ Florida, Dept Elect Engn, Gainesville, FL 32611 USA. EM li@dsp.ufl.edu FU Army Research Laboratory FX The authors of this paper would like to thank the Army Research Laboratory for their support and also for providing us with the dataset used for the experiments. NR 24 TC 0 Z9 0 U1 1 U2 5 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9505-1 J9 PROC SPIE PY 2013 VL 8714 AR UNSP 87140O DI 10.1117/12.2015618 PG 8 WC Optics; Telecommunications SC Optics; Telecommunications GA BGN39 UT WOS:000323559400020 ER PT S AU Phelan, BR Ressler, MA Mazzaro, GJ Sherbondy, KD Narayanan, RM AF Phelan, Brian R. Ressler, Marc A. Mazzaro, Gregory J. Sherbondy, Kelly D. Narayanan, Ram M. BE Ranney, KI Doerry, A TI Design of Spectrally Versatile Forward-Looking Ground Penetrating Radar for Detection of Concealed Targets SO RADAR SENSOR TECHNOLOGY XVII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Radar Sensor Technology XVII CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE Ground-Penetrating Radar; Concealed Targets; Spectrum Control; Stepped-Frequency Radar AB The design of high-resolution radars which can operate in theater involves a careful consideration of the radar's radiated spectrum. While a wide bandwidth yields better target detectability and classification, it can also interfere with other devices and/or violate federal and international communication laws. Under the Army Research Laboratory (ARL) Partnerships in Research Transition (PIRT) program, we are developing a Stepped-Frequency Radar (SFR) which allows for manipulation of the radiated spectrum, while still maintaining an effective ultra-wide bandwidth for achieving good range resolution. The SFR is a forward-looking, ultra-wideband (UWB) imaging radar capable of detecting concealed targets. This paper presents the research and analysis undertaken during the design of the SFR which will eventually complement an existing ARL system, the Synchronous Impulse REconstruction (SIRE) radar. The SFR is capable of excising prohibited frequency bands, while maintaining the down-range resolution capability of the original SIRE radar. The SFR has two transmit antennas and a 16-element receive antenna array, and this configuration achieves suitable cross-range resolution for target detection. The SFR, like the SIRE radar, is a vehicle mounted, forward-looking, ground penetrating radar (GPR) capable of using synthetic aperture radar (SAR) technology for the detection of subsurface targets via 3D imaging. Many contradicting design considerations are analyzed in this paper. The selection of system bandwidth, antenna types, number of antennas, frequency synthesizers, digitizers, receive amplifiers, wideband splitters, and many other components are critical to the design of the SFR. Leveraging commercial components and SIRE sub-systems were design factors offering an expedited time to the initial implementation of the radar while reducing overall costs. This SFR design will result in an ARL asset to support obscured target detection such as improvised explosive devices (IEDs) and landmines. C1 [Phelan, Brian R.; Narayanan, Ram M.] Penn State Univ, Dept Elect Engn, University Pk, PA 16802 USA. [Ressler, Marc A.; Mazzaro, Gregory J.; Sherbondy, Kelly D.] U S Army Res Lab, Adelphi, MD 20783 USA. RP Phelan, BR (reprint author), Penn State Univ, Dept Elect Engn, University Pk, PA 16802 USA. EM gregory.j.mazzaro.civ@mail.mil; ram@engr.psu.edu OI Sherbondy, Kelly/0000-0003-4730-3706 FU U.S. Army Research Office (ARO) through a Delaware State University (DESU) [W911NF-12-1-0305] FX This research was supported by U.S. Army Research Office (ARO) Contract # W911NF-12-1-0305 through a Delaware State University (DESU) subcontract. We appreciate helpful suggestions from Fengshan Liu and Jeffrey Sichina of DESU. NR 6 TC 0 Z9 0 U1 0 U2 6 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9505-1 J9 PROC SPIE PY 2013 VL 8714 AR UNSP 87140B DI 10.1117/12.2016650 PG 10 WC Optics; Telecommunications SC Optics; Telecommunications GA BGN39 UT WOS:000323559400008 ER PT S AU Ranney, K Liao, DH Dogaru, T Tran, C Nguyen, L AF Ranney, Kenneth Liao, DaHan Dogaru, Traian Tran, Chi Lam Nguyen BE Ranney, KI Doerry, A TI Buried target radar imaging with an ultra-wideband, vehicle-mounted antenna array SO RADAR SENSOR TECHNOLOGY XVII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Radar Sensor Technology XVII CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE Multi-static imaging; forward looking radar; ground penetrating radar; downward-looking radar AB The problem of detecting buried objects has engaged radar system developers for quite some time. Many systems-both experimental and commercial-have been developed, including vehicle-mounted systems that look beneath road surfaces. Most of these downward-looking systems exploit multiple transmit and receive channels to enhance resolution in the final radar imagery used for target detection. In such a system, the configuration and operation of the various transmit and receive elements play a critical role in the quality of the output imagery. In what follows, we leverage high-fidelity electromagnetic model data to examine a multistatic downward-looking radar system. We evaluate the signatures produced by various targets of interest and describe, both qualitatively and quantitatively, the variations in target signatures produced by different system configurations. Finally, we analyze the underlying physics of the problem to explain certain characteristics in the observed target signatures. C1 [Ranney, Kenneth; Liao, DaHan; Dogaru, Traian; Tran, Chi; Lam Nguyen] US Army Res Lab, Adelphi, MD 20783 USA. RP Ranney, K (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 10 TC 0 Z9 0 U1 0 U2 2 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9505-1 J9 PROC SPIE PY 2013 VL 8714 AR UNSP 87140K DI 10.1117/12.2018335 PG 11 WC Optics; Telecommunications SC Optics; Telecommunications GA BGN39 UT WOS:000323559400016 ER PT S AU Saponaro, P Kambhamettu, C Ranney, K Sullivan, A AF Saponaro, Philip Kambhamettu, Chandra Ranney, Kenneth Sullivan, Anders BE Ranney, KI Doerry, A TI Concealed Target Detection Using Augmented Reality with SIRE Radar SO RADAR SENSOR TECHNOLOGY XVII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Radar Sensor Technology XVII CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE Augmented Reality; Camera Calibration; Computer Vision; SIRE; Radar ID CAMERA CALIBRATION AB The Synchronous Impulse Reconstruction (SIRE) forward-looking radar, developed by the U. S. Army Research Laboratory (ARL), can detect concealed targets using ultra-wideband synthetic aperture technology. The SIRE radar has been mounted on a Ford Expedition and combined with other sensors, including a pan/tilt/zoom camera, to test its capabilities of concealed target detection in a realistic environment. Augmented Reality (AR) can be used to combine the SIRE radar image with the live camera stream into one view, which provides the user with information that is quicker to assess and easier to understand than each separated. In this paper we present an AR system which utilizes a global positioning system (GPS) and inertial measurement unit (IMU) to overlay a SIRE radar image onto a live video stream. We describe a method for transforming 3D world points in the UTM coordinate system onto the video stream by calibrating for the intrinsic parameters of the camera. This calibration is performed offline to save computation time and achieve real time performance. Since the intrinsic parameters are affected by the zoom of the camera, we calibrate at eleven different zooms and interpolate. We show the results of a real time transformation of the SAR imagery onto the video stream. Finally, we quantify both the 2D error and 3D residue associated with our transformation and show that the amount of error is reasonable for our application. C1 [Saponaro, Philip; Kambhamettu, Chandra] Univ Delaware, Dept Comp & Informat Sci, Video Image Modeling & Synth Lab, Newark, DE 19716 USA. [Ranney, Kenneth; Sullivan, Anders] U S Army Res Lab, Sensors & Elect Device Directorate, Adelphi, MD 20783 USA. RP Saponaro, P (reprint author), Univ Delaware, Dept Comp & Informat Sci, Video Image Modeling & Synth Lab, Newark, DE 19716 USA. FU US Army Research Laboratory; US Army Research Office [W911NF-11-2-0046] FX This material is based upon work supported in part by the US Army Research Laboratory and the US Army Research Office under cooperative agreement number W911NF-11-2-0046. We would like to acknowledge the support from members at the U.S. Army Research Lab including Lam Nguyen, Kelly Sherbondy, and Francois Koenig. NR 13 TC 0 Z9 0 U1 0 U2 2 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9505-1 J9 PROC SPIE PY 2013 VL 8714 AR UNSP 87140S DI 10.1117/12.2015133 PG 8 WC Optics; Telecommunications SC Optics; Telecommunications GA BGN39 UT WOS:000323559400024 ER PT S AU Tahmoush, D AF Tahmoush, Dave BE Ranney, KI Doerry, A TI Micro-Range Micro-Doppler for Dismount Classification SO RADAR SENSOR TECHNOLOGY XVII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Radar Sensor Technology XVII CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE Classification; micro-Doppler; surveillance; radar ID FEATURE-EXTRACTION; HUMAN GAIT; RADAR; MODEL AB This paper presents a processing technique that can be used to detect and classify pedestrians group based on the micro-Doppler signature gathered with a millimeter wave radar. The evaluation of the number of pedestrians moving in a group can be a difficult task using a traditional micro-Doppler spectrogram because of a tendency for people to partially synchronize their steps when walking together. The new approach, based on multi-range variation as well as the micro-Doppler variations, provides promising results. The range-spectrogram processing technique was developed and tested using a database composed of hundreds of pedestrian and vehicle signatures gathered in an urban test site over a two year period in a variety of weather conditions. We associate image detections with radar detections through motion extracted from both radar and imagery. We also explain how radar and video together can produce an inexpensive alternative to 3-D imaging. C1 US Army Res Lab, Adelphi, MD USA. RP Tahmoush, D (reprint author), US Army Res Lab, Adelphi, MD USA. NR 23 TC 1 Z9 1 U1 0 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9505-1 J9 PROC SPIE PY 2013 VL 8714 AR UNSP 87141E DI 10.1117/12.2015485 PG 7 WC Optics; Telecommunications SC Optics; Telecommunications GA BGN39 UT WOS:000323559400045 ER PT S AU Damarla, T Sabatier, JM AF Damarla, Thyagaraju Sabatier, James M. BE Carapezza, EM TI Estimation of target size using two passive infrared sensors SO SENSORS, AND COMMAND, CONTROL, COMMUNICATIONS, AND INTELLIGENCE (C3I) TECHNOLOGIES FOR HOMELAND SECURITY AND HOMELAND DEFENSE XII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Sensors, and Command, Control, Communications, and Intelligence (C3I) Technologies for Homeland Security and Homeland Defense XII CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE Personnel detection; Passive Infrared sensor; Fresnel lens; thermal radiation AB Passive infrared (PIR) sensors are widely used as a part of unattended ground sensor suite for situational awareness. Currently, the PIR sensor is mainly used as a wakeup sensor for the imaging sensor in order to conserve power. Since the PIR sensor mainly responds to the thermal radiation from the target, animals in the vicinity of the sensor can cause many false alarms. The number of false alarms can be cut drastically, if the target's size can be estimated and a decision is made based on target size. For example, if the target is 5 ft 9 in tall and 1.5 ft wide, it is most likely a human being as opposed to an animal. In this paper, we present a technique to estimate target size using two PIR sensors with Fresnel lens arrays. One of the PIR sensors is mounted such that its Fresnel zones are horizontal to the ground, and the second PIR sensor is mounted such that its Fresnel zones are at a slant angle to the horizontal plane. The former is used to estimate the width/length, while the latter is used to estimate the height of the target. The relative signal strength between the two sensors is used to estimate the distance of the target from the sensor. The time it takes to cross the Fresnel zones is used to estimate the speed of the target. The algorithm is tested using the data collected in the woods, where several animals are observed roaming. C1 [Damarla, Thyagaraju] US Army Res Lab, Networked Sensing & Fus Branch, Adelphi, MD USA. RP Damarla, T (reprint author), US Army Res Lab, Networked Sensing & Fus Branch, Adelphi, MD USA. EM thyagaraju.damarla.civ@mail.mil NR 1 TC 0 Z9 0 U1 0 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9502-0 J9 PROC SPIE PY 2013 VL 8711 AR UNSP 87110S DI 10.1117/12.2014954 PG 8 WC Engineering, Electrical & Electronic; Optics; Telecommunications SC Engineering; Optics; Telecommunications GA BGM80 UT WOS:000323522600018 ER PT S AU Ogaard, K Kase, S Roy, H Nagi, R Sambhoos, K Sudit, M AF Ogaard, Kirk Kase, Sue Roy, Heather Nagi, Rakesh Sambhoos, Kedar Sudit, Moises BE Carapezza, EM TI Searching Social Networks for Subgraph Patterns SO SENSORS, AND COMMAND, CONTROL, COMMUNICATIONS, AND INTELLIGENCE (C3I) TECHNOLOGIES FOR HOMELAND SECURITY AND HOMELAND DEFENSE XII SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Sensors, and Command, Control, Communications, and Intelligence (C3I) Technologies for Homeland Security and Homeland Defense XII CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE social network analysis; visualization software; graph matching AB Software tools for Social Network Analysis (SNA) are being developed which support various types of analysis of social networks extracted from social media websites (e.g., Twitter). Once extracted and stored in a database such social networks are amenable to analysis by SNA software. This data analysis often involves searching for occurrences of various subgraph patterns (i.e., graphical representations of entities and relationships). The authors have developed the Graph Matching Toolkit (GMT) which provides an intuitive Graphical User Interface (GUI) for a heuristic graph matching algorithm called the Truncated Search Tree (TruST) algorithm. GMT is a visual interface for graph matching algorithms processing large social networks. GMT enables an analyst to draw a subgraph pattern by using a mouse to select categories and labels for nodes and links from drop-down menus. GMT then executes the TruST algorithm to find the top five occurrences of the subgraph pattern within the social network stored in the database. GMT was tested using a simulated counter-insurgency dataset consisting of cellular phone communications within a populated area of operations in Iraq. The results indicated GMT (when executing the TruST graph matching algorithm) is a time-efficient approach to searching large social networks. GMT's visual interface to a graph matching algorithm enables intelligence analysts to quickly analyze and summarize the large amounts of data necessary to produce actionable intelligence. C1 [Ogaard, Kirk; Kase, Sue; Roy, Heather] US Army Res Lab, Tact Informat Fus Branch, Computat & Informat Sci Directorate, Aberdeen Proving Ground, MD USA. RP Ogaard, K (reprint author), US Army Res Lab, Tact Informat Fus Branch, Computat & Informat Sci Directorate, Aberdeen Proving Ground, MD USA. EM kirk.a.ogaard.ctr@mail.mil NR 10 TC 0 Z9 0 U1 0 U2 5 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9502-0 J9 PROC SPIE PY 2013 VL 8711 AR UNSP 87110T DI 10.1117/12.2015264 PG 11 WC Engineering, Electrical & Electronic; Optics; Telecommunications SC Engineering; Optics; Telecommunications GA BGM80 UT WOS:000323522600019 ER PT S AU Rudin, S Rupper, G Gutin, A Shur, M AF Rudin, S. Rupper, G. Gutin, A. Shur, M. BE Anwar, MF Crowe, TW Manzur, T TI Response of plasmonic terahertz detector to large signals: theory and experiment SO TERAHERTZ PHYSICS, DEVICES, AND SYSTEMS VII: ADVANCED APPLICATIONS IN INDUSTRY AND DEFENSE SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Terahertz Physics, Devices, and Systems VII - Advanced Applications in Industry and Defense CY APR 29-30, 2013 CL Baltimore, MD SP SPIE DE plasma resonance; HEMT; terahertz detector ID FIELD-EFFECT TRANSISTOR; RADIATION; FLUID AB In the Dyakonov-Shur terahertz (THz) detector, nonlinearities in the plasma wave propagation in the conduction channel of a heterostructure High Electron Mobility Transistor (HEMT) lead to a constant source-to-drain voltage providing the detector output. For a small signal, the perturbation theory treatment shows that the response is proportional to the intensity of the radiation. The proportionality factor can have a resonant or a broad dependence on the signal frequency. For submicron HEMTs, the typical measured response falls within the range of 0.1 to 4.5 THz. The deviations from this relation have been studied and reported in the approximation of the local Ohm's law and transmission line model for the non-resonant response. Here we present the results obtained with the hydrodynamic model using the electron plasma Navier-Stokes equation, thus fully accounting for the hydrodynamic non-linearity, the viscosity and pressure gradients in the detector response. The model is applicable to both resonant and broadband operations of the HEMT based plasmonic detectors. The relation between the electron channel density and gate voltage was modeled by the unified charge control model applicable both above and below the threshold voltage. The theoretical results are compared with the response measured in the short channel InGaAs HEMT and the analytical approximation. The THz source was operating at 1.63 THz and the response was measured at varying signal intensities. The response of the detector operated in the open drain mode was measured above and below the threshold. The theoretical and experimental results are in good agreement. C1 [Rudin, S.; Rupper, G.] Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. [Gutin, A.; Shur, M.] Rensselaer Polytech Inst, Troy, NY 12180 USA. RP Rudin, S (reprint author), Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. RI Shur, Michael/A-4374-2016 OI Shur, Michael/0000-0003-0976-6232 NR 17 TC 0 Z9 0 U1 0 U2 2 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9507-5 J9 PROC SPIE PY 2013 VL 8716 AR UNSP 87160D DI 10.1117/12.2015330 PG 11 WC Optics; Physics, Applied SC Optics; Physics GA BGO35 UT WOS:000323621000009 ER PT S AU Durst, PJ Gray, W Trentini, M AF Durst, Phillip J. Gray, Wendell Trentini, Michael BE Karlsen, RE Gage, DW Shoemaker, CM Gerhart, GR TI Development of a Non-Contextual Model for Determining the Autonomy Level of Intelligent Unmanned Systems SO UNMANNED SYSTEMS TECHNOLOGY XV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Unmanned Systems Technology XV CY MAY 01-03, 2013 CL Baltimore, MD SP SPIE AB A simple, quantitative measure for encapsulating the autonomous capabilities of unmanned systems (UMS) has yet to be established. Current models for measuring a UMS's autonomy level require extensive, operational level testing, and provide a means for assessing the autonomy level for a specific mission/task and operational environment. A more elegant technique for quantifying autonomy using component level testing of the robot platform alone, outside of mission and environment contexts, is desirable. Using a high level framework for UMS architectures, such a model for determining a level of autonomy has been developed. The model uses a combination of developmental and component level testing for each aspect of the UMS architecture to define a non-contextual autonomous potential (NCAP). The NCAP provides an autonomy level, ranging from fully non-autonomous to fully autonomous, in the form of a single numeric parameter describing the UMS's performance capabilities when operating at that level of autonomy. C1 [Durst, Phillip J.; Gray, Wendell] US Army Engineer Res & Dev Ctr, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. [Trentini, Michael] Def R&D Canada, Medicine Hat, AB T1A 8K6, Canada. RP Durst, PJ (reprint author), US Army Engineer Res & Dev Ctr, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM phillip.j.durst@usace.army.mil FU Geotechnical and Structures Laboratory FX Permission to publish was granted by the Director, Geotechnical and Structures Laboratory. NR 16 TC 0 Z9 0 U1 0 U2 0 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9532-7 J9 PROC SPIE PY 2013 VL 8741 AR UNSP 874111 DI 10.1117/12.2014352 PG 10 WC Engineering, Electrical & Electronic; Robotics; Optics SC Engineering; Robotics; Optics GA BGN01 UT WOS:000323543800035 ER PT S AU Gregory, J Baran, D Rogers, J Fink, J Delmerico, J AF Gregory, Jason Baran, David Rogers, John, III Fink, Jonathan Delmerico, Jeffrey BE Karlsen, RE Gage, DW Shoemaker, CM Gerhart, GR TI Collaborative experiments of small, autonomous systems at the SOURCE ATO Capstone Experiment SO UNMANNED SYSTEMS TECHNOLOGY XV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Unmanned Systems Technology XV CY MAY 01-03, 2013 CL Baltimore, MD SP SPIE DE SOURCE ATO; autonomous systems; mapping; exploration; communications maintenance; visual intelligence ID ROBOT AB Autonomous systems operating in militarily-relevant environments are valuable assets due to the increased situational awareness they provide to the Warfighter. To further advance the current state of these systems, a collaborative experiment was conducted as part of the Safe Operations of Unmanned Systems for Reconnaissance in Complex Environments (SOURCE) Army Technology Objective (ATO). We present the findings from this large-scale experiment which spanned several research areas, including 3D mapping and exploration, communications maintenance, and visual intelligence. For 3D mapping and exploration, we evaluated loop closure using Iterative Closest Point (ICP). To improve current communications systems, the limitations of an existing mesh network were analyzed. Also, camera data from a Microsoft Kinect was used to test autonomous stairway detection and modeling algorithms. This paper will detail the experiment procedure and the preliminary results for each of these tests. C1 [Gregory, Jason; Baran, David; Rogers, John, III; Fink, Jonathan; Delmerico, Jeffrey] US Army Res Lab, Adelphi, MD 20783 USA. RP Gregory, J (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 12 TC 0 Z9 0 U1 0 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9532-7 J9 PROC SPIE PY 2013 VL 8741 AR UNSP 87410X DI 10.1117/12.2016284 PG 12 WC Engineering, Electrical & Electronic; Robotics; Optics SC Engineering; Robotics; Optics GA BGN01 UT WOS:000323543800031 ER PT S AU Gregory, J Baran, D Evans, AW AF Gregory, Jason Baran, David Evans, A. William, III BE Karlsen, RE Gage, DW Shoemaker, CM Gerhart, GR TI Evaluating the presentation and usability of 2D and 3D maps generated by unmanned ground vehicles SO UNMANNED SYSTEMS TECHNOLOGY XV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Unmanned Systems Technology XV CY MAY 01-03, 2013 CL Baltimore, MD SP SPIE DE 2D Maps; 3D Maps; Human Robot Interaction AB Currently fielded small unmanned ground vehicles (SUGVs) are operated via teleoperation. This method of operation requires a high level of operator involvement within, or near within, line of sight of the robot. As advances are made in autonomy algorithms, capabilities such as automated mapping can be developed to allow SUGVs to be used to provide situational awareness with an increased standoff distance while simultaneously reducing operator involvement. In order to realize these goals, it is paramount the data produced by the robot is not only accurate, but also presented in an intuitive manner to the robot operator. The focus of this paper is how to effectively present map data produced by a SUGV in order to drive the design of a future user interface. The effectiveness of several 2D and 3D mapping capabilities was evaluated by presenting a collection of pre-recorded data sets of a SUGV mapping a building in an urban environment to a user panel of Soldiers. The data sets were presented to each Soldier in several different formats to evaluate multiple factors, including update frequency and presentation style. Once all of the data sets were presented, a survey was administered. The questions in the survey were designed to gauge the overall usefulness of the mapping algorithm presentations as an information generating tool. This paper presents the development of this test protocol along with the results of the survey. C1 [Gregory, Jason; Baran, David; Evans, A. William, III] US Army Res Lab, Adelphi, MD 20783 USA. RP Gregory, J (reprint author), US Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 6 TC 0 Z9 0 U1 0 U2 1 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9532-7 J9 PROC SPIE PY 2013 VL 8741 AR UNSP 87410G DI 10.1117/12.2016316 PG 10 WC Engineering, Electrical & Electronic; Robotics; Optics SC Engineering; Robotics; Optics GA BGN01 UT WOS:000323543800015 ER PT S AU Pusey, JL Duperret, JM Haynes, GC Knopf, R Koditschek, DE AF Pusey, Jason L. Duperret, Jeffrey M. Haynes, G. Clark Knopf, Ryan Koditschek, Daniel E. BE Karlsen, RE Gage, DW Shoemaker, CM Gerhart, GR TI Free-Standing Leaping Experiments with a Power-Autonomous, Elastic-Spined Quadruped SO UNMANNED SYSTEMS TECHNOLOGY XV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Unmanned Systems Technology XV CY MAY 01-03, 2013 CL Baltimore, MD SP SPIE DE Legged Robot; Modular robot; Bounding quadruped; Flexible Spine; Robot design ID ROBOT; GAIT; HEXAPOD; WALKING; SPEED; MODEL AB We document initial experiments with Canid, a freestanding, power-autonomous quadrupedal robot equipped with a parallel actuated elastic spine. Research into robotic bounding and galloping platforms holds scientific and engineering interest because it can both probe biological hypotheses regarding bounding and galloping mammals and also provide the engineering community with a new class of agile, efficient and rapidly-locomoting legged robots. We detail the design features of Canid that promote our goals of agile operation in a relatively cheap, conventionally prototyped, commercial off-the-shelf actuated platform. We introduce new measurement methodology aimed at capturing our robot's "body energy" during real time operation as a means of quantifying its potential for agile behavior. Finally, we present joint motor, inertial and motion capture data taken from Canid's initial leaps into highly energetic regimes exhibiting large accelerations that illustrate the use of this measure and suggest its future potential as a platform for developing efficient, stable, hence useful bounding gaits. C1 [Pusey, Jason L.] US Army Res Lab, Aberdeen Proving Ground, MD USA. RP Pusey, JL (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD USA. FU National Science Foundation Graduate Research Fellowship [DGE-0822]; Army Research Laboratory [W911NF-10-2-0016] FX The authors thank members of Kod*lab within Penn's GRASP lab for many helpful discussions and a significant amount of assistance in running experiments. This work is supported by the National Science Foundation Graduate Research Fellowship under Grant Number DGE-0822, and by the Army Research Laboratory under Cooperative Agreement Number W911NF-10-2-0016. NR 48 TC 0 Z9 0 U1 1 U2 4 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9532-7 J9 PROC SPIE PY 2013 VL 8741 AR UNSP 87410W DI 10.1117/12.2016073 PG 15 WC Engineering, Electrical & Electronic; Robotics; Optics SC Engineering; Robotics; Optics GA BGN01 UT WOS:000323543800030 ER PT S AU Rogers, JG Young, S Gregory, J Nieto-Granda, C Christensen, HI AF Rogers, John G., III Young, Stuart Gregory, Jason Nieto-Granda, Carlos Christensen, Henrik I. BE Karlsen, RE Gage, DW Shoemaker, CM Gerhart, GR TI Robot mapping in large-scale mixed indoor and outdoor environments SO UNMANNED SYSTEMS TECHNOLOGY XV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Unmanned Systems Technology XV CY MAY 01-03, 2013 CL Baltimore, MD SP SPIE DE Mapping; sensor fusion; mobile robotics AB Tactical situational awareness in unstructured and mixed indoor/ outdoor scenarios is needed for urban combat as well as rescue operations. Two of the key functionalities needed by robot systems to function in an unknown environment are the ability to build a map of the environment and to determine its position within that map. In this paper, we present a strategy to build dense maps and to automatically close loops from 3D point clouds; this has been integrated into a mapping system dubbed OmniMapper. We will present both the underlying system, and experimental results from a variety of environments such as office buildings, at military training facilities and in large scale mixed indoor and outdoor environments. C1 [Rogers, John G., III; Young, Stuart; Gregory, Jason] Army Res Lab, Adelphi, MD USA. RP Rogers, JG (reprint author), Army Res Lab, Adelphi, MD USA. EM jgrogers@gmail.com NR 15 TC 0 Z9 0 U1 0 U2 6 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9532-7 J9 PROC SPIE PY 2013 VL 8741 AR UNSP 874107 DI 10.1117/12.2015955 PG 10 WC Engineering, Electrical & Electronic; Robotics; Optics SC Engineering; Robotics; Optics GA BGN01 UT WOS:000323543800006 ER PT S AU Bender, EJ Wood, MV Hosek, DJ Hart, SD AF Bender, Edward J. Wood, Michael V. Hosek, Daniel J. Hart, Steve D. BE Holst, GC Krapels, KA TI Characterization of domestic and foreign image intensifier tubes SO INFRARED IMAGING SYSTEMS: DESIGN, ANALYSIS, MODELING, AND TESTING XXIV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Infrared Imaging Systems - Design, Analysis, Modeling, and Testing XXIV CY APR 30-MAY 02, 2013 CL Baltimore, MD SP SPIE DE Generation 2; Generation 3; image intensifier tubes; I2; luminance gain; EBI; SNR; resolution; halo; MTF; auto-gating; non-gated AB The market for military-use Generation 2 and Generation 3 image intensifier (I2) tubes has become truly global, with major manufacturers and customers spanning five continents. This worldwide market is becoming increasingly important to U. S. manufacturers, with the majority of U. S. Army intensifier fielding having been completed in 2012. Given this keen global competition, it is not surprising that the advertised tube performance of a given source is often discounted by competitors, and the customers have no objective "honest broker" to determine the relative accuracy of these claims. To help fill this void, the U. S. Army RDECOM CERDEC NVESD recently measured a number of domestic and foreign image intensifier tubes, using consistent test equipment/procedures with which the U. S. industry must correlate for Army tube deliveries. Data and analysis will be presented for the major tube parameters of luminance gain, equivalent background input (EBI), signal-to-noise ratio (SNR), limiting resolution, halo, and modulation transfer function (MTF). The bright-light resolution provided by various auto-gated and non-gated tubes will also be addressed, since this area has been an important factor in the international market. RDECOM CERDEC NVESD measurement data will be compared to the corresponding manufacturer specifications whenever possible. C1 [Bender, Edward J.; Wood, Michael V.; Hosek, Daniel J.; Hart, Steve D.] US Army, RDECOM CERDEC Night Vis & Elect Sensors Directora, Ft Belvoir, VA 22060 USA. RP Bender, EJ (reprint author), US Army, RDECOM CERDEC Night Vis & Elect Sensors Directora, Ft Belvoir, VA 22060 USA. NR 5 TC 1 Z9 1 U1 0 U2 1 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9497-9 J9 PROC SPIE PY 2013 VL 8706 AR UNSP 870607 DI 10.1117/12.2015462 PG 11 WC Optics; Imaging Science & Photographic Technology SC Optics; Imaging Science & Photographic Technology GA BGL88 UT WOS:000323445000005 ER PT S AU Dobbins, CL Dawson, JA Lightfoot, JA Edwards, WD AF Dobbins, Christopher L. Dawson, James A. Lightfoot, Jay A. Edwards, William D. BE Holst, GC Krapels, KA TI Compensation for instrument anomalies in imaging infrared measurements SO INFRARED IMAGING SYSTEMS: DESIGN, ANALYSIS, MODELING, AND TESTING XXIV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Infrared Imaging Systems - Design, Analysis, Modeling, and Testing XXIV CY APR 30-MAY 02, 2013 CL Baltimore, MD SP SPIE DE Infrared Detectors; Thermal Imaging; Dark Current; Cooled Detectors; Infrared Cameras; Calibration AB Infrared imaging is commonly used for performing thermography based on field calibration that simply relates image levels to apparent temperature levels using field blackbodies. Under normal conditions, the correlation between the image levels and blackbody temperature is strong, allowing conversion of the raw data into units of blackbody-equivalent temperature without consideration of other factors. However, if certain instrument anomalies are present, a compensation procedure that involves more in-depth sensor characterization may be required. The procedure, which uses an analysis of temperature-dependent dark current, optical emissions, and detector response, is described along with results for a specific case. The procedure involves first cold soaking a thermal camera and then observing the cooldown behavior of the sensor under non-stressing conditions. Variations in environmental temperature levels are then used to observe cooler performance and dark current levels. A multi-variate linear regression is performed that allows temperature-dependent dark current, lens emission, lens transmission, and detector quantum efficiency to be fully characterized. The resulting data describe for each image pixel a relationship between the scene temperature and the observed values of image signal, detector temperature, and camera temperature. The procedure has been applied successfully to a thermal imager used to collect field data while suffering from instrument anomalies due to a faulty cooler. Using the resulting characterization data for the pixel-dependent dark current, image data collected with the thermal imager was compensated. The compensation involved using spatial filtering to determine temperature shifts caused by the faulty cooler based on the predictable pattern of pixel-to-pixel variations in dark current. The estimated temperature shift was used to compute a compensation offset for each pixel based on its known dark current coefficient. The compensated image data, while still degraded, was sufficiently corrected for the predictable effects of dark current variations to allow valid thermography to be performed. C1 [Dobbins, Christopher L.] US Army, Aviat & Missile Res Dev & Engn Ctr, Redstone Arsenal, AL 35898 USA. RP Dobbins, CL (reprint author), US Army, Aviat & Missile Res Dev & Engn Ctr, ATTN RDMR WDG 1, Redstone Arsenal, AL 35898 USA. EM james.dawson@dynetics.com NR 7 TC 0 Z9 0 U1 1 U2 4 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9497-9 J9 PROC SPIE PY 2013 VL 8706 AR UNSP 870606 DI 10.1117/12.2015473 PG 11 WC Optics; Imaging Science & Photographic Technology SC Optics; Imaging Science & Photographic Technology GA BGL88 UT WOS:000323445000004 ER PT S AU Friedman, M AF Friedman, Melvin BE Holst, GC Krapels, KA TI Mean time for target acquisition in collaborative search with multiple imaging sensors SO INFRARED IMAGING SYSTEMS: DESIGN, ANALYSIS, MODELING, AND TESTING XXIV SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Infrared Imaging Systems - Design, Analysis, Modeling, and Testing XXIV CY APR 30-MAY 02, 2013 CL Baltimore, MD SP SPIE AB In this paper the mean time to acquire a stationary target by n stationary imaging sensors is computed using probability theory by making use of the well established result that the detection time for a single imaging sensor is a random variable from an exponential probability density function. Each imaging sensor is characterized by a separate P-infinity value which describes the probability an observer using that sensor will eventually acquire the target and a separate tau value which describes the mean time to acquire the target using that sensor. There is no restriction on the wavelength band used by the imaging sensor. There are no empirical constants in the model presented here and the results are in agreement with and generalize previously published equations. The newly developed equations have been verified by numerical simulations and also yield the expected mean detection time for all limiting values of the input parameters. The code used in the numerical simulations is exhibited. For any given scenario, the separate observer-sensor-target parameters P-infinity and tau can be estimated using the NV-IPM model or measured in perception experiments. Thus the input parameters needed by the model are generally available. Comparing results presented here with results from war game simulations such as OneSAF may improve the quality of both products. C1 US Army RDECOM, Commun Elect Res Dev & Engn Ctr, Night Vis & Elect Sensors Directorate, Ft Belvoir, VA 22060 USA. RP Friedman, M (reprint author), US Army RDECOM, Commun Elect Res Dev & Engn Ctr, Night Vis & Elect Sensors Directorate, Ft Belvoir, VA 22060 USA. EM info@nvl.army.mil NR 6 TC 1 Z9 1 U1 0 U2 0 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9497-9 J9 PROC SPIE PY 2013 VL 8706 AR UNSP 87060E DI 10.1117/12.2018349 PG 16 WC Optics; Imaging Science & Photographic Technology SC Optics; Imaging Science & Photographic Technology GA BGL88 UT WOS:000323445000011 ER PT S AU Fleischman, ZD Merkle, LD Newburgh, GA Dubinskii, M AF Fleischman, Z. D. Merkle, L. D. Newburgh, G. A. Dubinskii, M. BE Dubinskii, M Post, SG TI Temperature-dependent spectroscopy of Ho3+:YVO4 relevant to 2-mu m laser operation SO LASER TECHNOLOGY FOR DEFENSE AND SECURITY IX SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Laser Technology for Defense and Security IX CY APR 30-MAY 01, 2013 CL Baltimore, MD SP SPIE DE Laser materials; Rare Earth; Infrared Spectroscopy ID DIODE; CRYSTALS; SPECTRA; SYSTEM; RADAR AB The spectroscopic properties of Ho3+-doped YVO4 were studied at cryogenic and room temperatures in the 2 mu m spectral region to clarify recent observations of efficient dual-wavelength laser operation in this material. Polarized absorption cross sections were measured, and stimulated emission cross sections were determined using the reciprocity method coupled with Fuchtbauer-Ladenburg calculations. The observed laser emission wavelengths were at 2041.7 nm, 2054.2 nm, and 2068.5 nm; the first two corresponding to pi transitions and the third to a sigma transition. Gain cross section calculations were used to predict which of the three wavelengths would lase for a given output coupler reflectivity. In depth analysis of the gain cross section in the region between 80 K and 100 K showed that the laser output wavelength is very susceptible to minor changes in temperature. C1 [Fleischman, Z. D.; Merkle, L. D.; Newburgh, G. A.; Dubinskii, M.] US Army, Res Lab, Adelphi, MD 20783 USA. RP Fleischman, ZD (reprint author), US Army, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM zackery.d.fleischman.ctr@mail.mil NR 22 TC 1 Z9 1 U1 0 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9524-2 J9 PROC SPIE PY 2013 VL 8733 AR UNSP 87330G DI 10.1117/12.2017758 PG 8 WC Optics; Physics, Applied SC Optics; Physics GA BGK51 UT WOS:000323328800012 ER PT S AU Merkle, LD Ter-Gabrielyan, N AF Merkle, Larry D. Ter-Gabrielyan, Nikolay BE Dubinskii, M Post, SG TI Er-doped sesquioxides for 1.5-micron lasers - spectroscopic comparisons SO LASER TECHNOLOGY FOR DEFENSE AND SECURITY IX SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Laser Technology for Defense and Security IX CY APR 30-MAY 01, 2013 CL Baltimore, MD SP SPIE DE sesquioxide; erbium; Lu2O3; Sc2O3; Y2O3; absorption; stimulated emission AB Due to the favorable thermal properties of sesquioxides as hosts for rare earth laser ions, we have recently studied the spectroscopy of Er:Lu2O3 in the 1400-1700 nm wavelength range, and here report its comparison with our earlier results on Er:Y2O3 and Er:Sc2O3. These studies include absorption and fluorescence spectra, fluorescence lifetimes, and inference of absorption and stimulated emission cross sections, all as a function of temperature. At room temperature, optical absorption limits practical laser operation to wavelengths longer than about 1620 nm. In that spectral range, the strongest stimulated emission peak is that at 1665 nm in Er:Sc2O3, with an effective cross section considerably larger than those of Er:Y2O3 and Er:Lu2O3. At 77K, the absorption is weak enough for efficient laser operation at considerably shorter wavelengths, where there are peaks with much larger stimulated emission cross sections. The three hosts all have peaks near 1575-1580 nm with comparably strong cross sections. As we have reported earlier, it is possible to lase even shorter wavelengths efficiently at this temperature, in particular the line at 1558 nm in Er:Sc2O3. Our new spectroscopic studies of Er:Lu2O3 indicate that its corresponding peak, like that of Er:Y2O3, has a less favorable ratio of stimulated emission to absorption cross sections. Reasons for the differences will be discussed. We conclude that for most operating scenarios, Er:Sc2O3 is the most promising of the Er-doped sesquioxides studied for laser operation around 1.5-1.6 microns. C1 [Merkle, Larry D.; Ter-Gabrielyan, Nikolay] US Army, Res Lab, ATTN RDRL SEE M, Adelphi, MD 20783 USA. RP Merkle, LD (reprint author), US Army, Res Lab, ATTN RDRL SEE M, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM larry.d.merkle.civ@mail.mil NR 10 TC 1 Z9 1 U1 2 U2 5 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9524-2 J9 PROC SPIE PY 2013 VL 8733 AR UNSP 87330H DI 10.1117/12.2017873 PG 8 WC Optics; Physics, Applied SC Optics; Physics GA BGK51 UT WOS:000323328800013 ER PT S AU Ter-Gabrielyan, N Fromzel, V Mu, X Meissner, H Dubinskii, M AF Ter-Gabrielyan, N. Fromzel, V. Mu, X. Meissner, H. Dubinskii, M. BE Dubinskii, M Post, SG TI Highly efficient resonantly pumped Er:YAG large area waveguide laser with diffraction limited output SO LASER TECHNOLOGY FOR DEFENSE AND SECURITY IX SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Laser Technology for Defense and Security IX CY APR 30-MAY 01, 2013 CL Baltimore, MD SP SPIE DE Lasers; solid-state; Lasers; Er:YAG; Lasers; Waveguide AB We demonstrated nearly a quantum defect limited CW operation of a 41-mm-long Er:YAG large area crystalline waveguide laser with a diffraction limited output, which was resonantly pumped by a fiber laser at 1532 nm. Using a Er(0.25%): YAG, 62 mu m x 62 mu m waveguide, surrounded by a 3 x 5 mm rectangular cladding of undoped YAG, an output power of 9.1 W with slope efficiency of 92.8% has been achieved. The output laser beam had a Gaussian profile with a similar to 2.8 x 10(-2) rad divergence, which is in good agreement with the divergence expected from a waveguide with a low NA value. The waveguide laser operated simultaneously at two wavelengths, 1617 nm and 1645 nm, when the transmission of the laser cavity output coupler was less than 20-25%, and operated only at 1617 nm when the laser output mirror had a higher transmission. C1 [Ter-Gabrielyan, N.; Fromzel, V.; Dubinskii, M.] US Army, Res Lab, Adelphi, MD 20783 USA. RP Ter-Gabrielyan, N (reprint author), US Army, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 8 TC 0 Z9 0 U1 0 U2 6 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9524-2 J9 PROC SPIE PY 2013 VL 8733 AR UNSP 87330L DI 10.1117/12.1518452 PG 6 WC Optics; Physics, Applied SC Optics; Physics GA BGK51 UT WOS:000323328800016 ER PT S AU Lee, IC Gamson, A Mitchell, J AF Lee, Ivan C. Gamson, Adam Mitchell, Jonathan BE Tunick, MH Onwulata, CI TI High-Performance Thin Layer Chromatography and Raman Microscopy of Cotton and Other Seed Oils SO PHYSICAL METHODS IN FOOD ANALYSIS SE ACS Symposium Series LA English DT Proceedings Paper CT Symposium on Physical Methods in Food Analysis / Fall National Meeting of the American-Chemical-Society CY AUG 19-23, 2012 CL Philadelphia, PA SP Amer Chem Soc, Div Agr & Food Chem Inc ID CYCLOPROPENOID FATTY-ACIDS; LIPID CLASSES; L.; PHOSPHOLIPIDS; DISTRIBUTIONS; ADULTERATION; BIODIESEL; VISCOSITY; FUEL AB Cotton seed oil is a renewable resource that can potentially be blended with fossil fuels for power generation. The primary objective of this work was to identify analytical techniques that can be performed on the field to discern poppy seed oil from cotton seed oil. It was determined that it is feasible to distinguish poppy and cotton seed oil samples using reverse phase high performance thin layer chromatography (HPTLC) and viscosity measurement. Other seed oils including soybean and canola seed oils were also evaluated to understand the limitations of these analytical techniques. Viscosity measurement was determined to be effective to distinguish cotton seed oil from poppy or soybean seed oil, but it failed to distinguish cotton and canola seed oils. To maximize the HPTLC separation of the oils without pretreatment, different solvent mixtures were studied: isopropyl alcohol, 1-butanol, methanol, hexane, dioxane, and distilled water. The purpose of mixing solvents was to tailor a solution with moderate polarity to achieve the best separation with the HPTLC plates. The most promising mixtures were butanol-methanol at the ratio of 80:20% and 90:10%. In the 80:20 mixture, R-f values increased in the order of poppy, canola, cotton, and soybean, while in the 90:10 mixture the order was reversed. With this technique the oil polarity can be ranked in increasing polarity: poppy < canola < cotton < soybean. This showed that the various compounds making up the oil have varying levels of polarity, and thus lessen in concentration at varying levels as the analyte moves up the plate. Raman spectroscopy (microscopy) was employed to characterize the oils by locating cis C=C vibrational peak at 1654cm(-1) on the oil smear that decreased as the analyte moved up the stationary phase. C1 [Lee, Ivan C.; Gamson, Adam; Mitchell, Jonathan] US Army Res Lab, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA. RP Lee, IC (reprint author), US Army Res Lab, Sensors & Electron Devices Directorate, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM ivan.c.lee2.civ@mail.mil RI jingjing, cai/M-2687-2013 NR 33 TC 1 Z9 1 U1 1 U2 8 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 SIXTEENTH ST NW, WASHINGTON, DC 20036 USA SN 0097-6156 BN 978-0-8412-2884-9 J9 ACS SYM SER JI ACS Symp. Ser. PY 2013 VL 1138 BP 1 EP 16 PG 16 WC Chemistry, Applied; Chemistry, Analytical; Food Science & Technology SC Chemistry; Food Science & Technology GA BGK24 UT WOS:000323291900001 ER PT S AU Good, CH AF Good, Cameron H. BE Southern, SO TI A review of glutamate's role in traumatic brain injury mechanisms SO SENSING TECHNOLOGIES FOR GLOBAL HEALTH, MILITARY MEDICINE, AND ENVIRONMENTAL MONITORING III SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring III CY APR 29-MAY 01, 2013 CL Baltimore, MD SP SPIE DE glutamate; TBI; blast; astrocyte; seizure; AMPA; NMDA; excitotoxicity ID FIBRILLARY ACIDIC PROTEIN; SYNAPTIC PLASTICITY; SUBUNIT COMPOSITION; GLUR2 ENDOCYTOSIS; CORTICAL-NEURONS; NMDA RECEPTORS; PHOSPHORYLATION; RAT; EPILEPSY; IMPACT AB Glutamate is the primary excitatory neurotransmitter used by the central nervous system (CNS) for synaptic communication, and its extracellular concentration is tightly regulated by glutamate transporters located on nearby astrocytes. Both animal models and human clinical studies have demonstrated elevated glutamate levels immediately following a traumatic brain event, with the duration and severity of the rise corresponding to prognosis. This rise in extracellular glutamate likely results from a combination of excessive neurotransmitter release from damaged neurons and down regulation of uptake mechanisms in local astrocytes. The immediate results of a traumatic event can lead to necrotic tissue in severely injured regions, while prolonged increases in excitatory transmission can cause secondary excitotoxic injury through activation of delayed apoptotic pathways. Initial TBI animal studies utilized a variety of broad glutamate receptor antagonists to successfully combat secondary injury mechanisms, but unfortunately this same strategy has proven inconclusive in subsequent human trials due to deleterious side effects and heterogeneity of injuries. More recent treatment strategies have utilized specific glutamate receptor subunit antagonists in an effort to minimize side effects and have shown promising results. Future challenges will be detecting the concentration and kinetics of the glutamate rise following injury, determining which patient populations could benefit from antagonist treatment based on their extracellular glutamate concentrations and when drugs should be administered to maximize efficacy. C1 US Army Res Lab ARL, HRED, Aberdeen Proving Ground, MD USA. RP Good, CH (reprint author), US Army Res Lab ARL, HRED, Aberdeen Proving Ground, MD USA. EM cameron.good.ctr@mail.mil NR 43 TC 0 Z9 0 U1 0 U2 4 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9514-3 J9 PROC SPIE PY 2013 VL 8723 AR UNSP 87230Q DI 10.1117/12.2021764 PG 8 WC Remote Sensing; Optics SC Remote Sensing; Optics GA BGL64 UT WOS:000323425300009 ER PT J AU Smith, D Alverdy, J An, G Coleman, M Garcia-Houchins, S Green, J Keegan, K Kelley, ST Kirkup, BC Kociolek, L Levin, H Landon, E Olsiewski, P Knight, R Siegel, J Weber, S Gilbert, J AF Smith, Daniel Alverdy, John An, Gary Coleman, Maureen Garcia-Houchins, Sylvia Green, Jessica Keegan, Kevin Kelley, Scott T. Kirkup, Benjamin C. Kociolek, Larry Levin, Hal Landon, Emily Olsiewski, Paula Knight, Rob Siegel, Jeffrey Weber, Stephen Gilbert, Jack TI The Hospital Microbiome Project: Meeting Report for the 1st Hospital Microbiome Project Workshop on sampling design and building science measurements, Chicago, USA, June 7th-8th 2012 SO STANDARDS IN GENOMIC SCIENCES LA English DT Article AB This report details the outcome of the 1st Hospital Microbiome Project workshop held on June 7th-8th, 2012 at the University of Chicago, USA. The workshop was arranged to determine the most appropriate sampling strategy and approach to building science measurement to characterize the development of a microbial community within a new hospital pavilion being built at the University of Chicago Medical Center. The workshop made several recommendations and led to the development of a full proposal to the Alfred P. Sloan Foundation as well as to the creation of the Hospital Microbiome Consortium. C1 [Smith, Daniel; Keegan, Kevin; Gilbert, Jack] Argonne Natl Lab, Argonne, IL 60439 USA. [Alverdy, John; An, Gary] Univ Chicago, Dept Surg, Chicago, IL 60637 USA. [Coleman, Maureen] Univ Chicago, Dept Geophys Sci, Chicago, IL 60637 USA. [Garcia-Houchins, Sylvia; Weber, Stephen] Univ Chicago UCMC Infect Control, Chicago, IL 60637 USA. [Green, Jessica] Univ Oregon, Inst Ecol & Evolut, Eugene, OR 97403 USA. [Kelley, Scott T.] San Diego State Univ, Dept Biol, San Diego, CA 92182 USA. [Kirkup, Benjamin C.] Walter Reed Army Inst Res, Dept Wound Infect, Silver Spring, MD 20910 USA. [Kirkup, Benjamin C.] Uniformed Serv Univ Hlth Sci, F Edward Hebert Sch Med, Bethesda, MD 20814 USA. [Kociolek, Larry] Ann & Robert H Lurie Childrens Hosp Chicago, Div Infect Dis, Dept Pediat, Chicago, IL 60611 USA. [Levin, Hal] Bldg Ecol Res Grp, Santa Cruz, CA 95060 USA. [Landon, Emily] Univ Chicago, Med Ctr, Chicago, IL 60637 USA. [Olsiewski, Paula] Alfred P Sloan Fdn, New York, NY 10111 USA. [Knight, Rob] Univ Colorado, Howard Hughes Med Inst, Boulder, CO 80309 USA. [Knight, Rob] Univ Colorado, Dept Chem & Biochem, Boulder, CO 80309 USA. [Siegel, Jeffrey] Univ Texas Austin, Civil Archectural & Environm Engn Dept, Austin, TX 78712 USA. [Gilbert, Jack] Univ Chicago, Dept Ecol & Evolut, Chicago, IL 60637 USA. RP Smith, D (reprint author), Argonne Natl Lab, 9700 S Cass Ave, Argonne, IL 60439 USA. RI Kirkup, Benjamin/C-3610-2009; Knight, Rob/D-1299-2010; OI Kirkup, Benjamin/0000-0002-8722-6218; Kociolek, Larry/0000-0002-8756-3417; An, Gary/0000-0003-4549-9004 FU APSF; US Dept. of Energy [DE-AC02-06CH11357]; Argonne, a US Department of Energy Office of Science laboratory [DE-AC02-06CH11357] FX We acknowledge the APSF for funding this workshop. This work was supported in part by the US Dept. of Energy under Contract DE-AC02-06CH11357. The submitted manuscript has been created in part by UChicago Argonne, LLC, Operator of Argonne National Laboratory ("Argonne"). Argonne, a US Department of Energy Office of Science laboratory, is operated under Contract No. DE-AC02-06CH11357. The US Government retains for itself, and others acting on its behalf, a paid-up non-exclusive, irrevocable worldwide license in said article to reproduce, prepare derivative works, distribute copies to the public, and perform publicly and display publicly, by or on behalf of the Government. NR 6 TC 6 Z9 6 U1 0 U2 19 PU GENOMIC STAND CONSORT PI EAST LANSING PA MICHIGAN STATE UNIV, GEEO GARRITY, DEPT MICROBIOL, 6162 BIOMED & PHYS SCI BLDG, EAST LANSING, MI 48824 USA SN 1944-3277 J9 STAND GENOMIC SCI JI Stand. Genomic Sci. PY 2013 VL 8 IS 1 BP 112 EP 117 DI 10.4056/sigs.3717348 PG 6 WC Genetics & Heredity; Microbiology SC Genetics & Heredity; Microbiology GA 203WP UT WOS:000323325500010 PM 23961316 ER PT S AU Zhou, WM Dang, G Taysing-lara, M Chang-Hasnain, C AF Zhou, Weimin Dang, Gerard Taysing-lara, Monica Chang-Hasnain, Connie BE ChangHasnain, CJ Koyama, F Willner, AE Zhou, W TI Demonstration of a Slow-Light High-Contrast Metastructure Cage Waveguide SO HIGH CONTRAST METASTRUCTURES II SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on High Contrast Metastructures II CY FEB 05-07, 2013 CL San Francisco, CA SP SPIE DE optical hollow-core waveguide; metastructure; high contrast grating; slow-light AB We have developed a new type of Si-based 3D cage-like high-contrast metastructure waveguide with both "slow-light" and low-loss properties, which has applications in providing a long time-delay line or a high Q cavity in chip-scale opto-electronic integrated circuits (OEIC). Traditional semiconductor optical waveguides always have high loss when used in a high dispersion (slow-light) region. A preliminary computational model has predicted that there is a slow-light and low propagation loss region within cage-like hollow-core waveguide formed by 4 high-contrast-gratings walls/claddings. Using our new processing technique, we fabricated several such waveguides on a Si wafer with different core sizes/shapes and different HCGs for 1550 operation wavelength. We have conducted experimental waveguide delay test measurements using a short optical pulse which indicate that the group velocity of these metastructure waveguides are in the range of 20- 30% of the speed of the light. Using a waveguide "cut-back" method, we have experimentally determined the propagation loss of these waveguides are in the range of 2-5dB/cm. We are also developing this type of high-contrast metastructure hollow-core waveguide for different operating wavelength/frequency such as THz for different applications. C1 [Zhou, Weimin; Dang, Gerard; Taysing-lara, Monica] US Army Res Lab, Adelphi, MD 20783 USA. RP Zhou, WM (reprint author), US Army Res Lab, Adelphi, MD 20783 USA. NR 10 TC 2 Z9 2 U1 1 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9402-3 J9 PROC SPIE PY 2013 VL 8633 AR 863305 DI 10.1117/12.2002071 PG 9 WC Optics; Physics, Multidisciplinary SC Optics; Physics GA BGH39 UT WOS:000322969400006 ER PT J AU Deems, JS Painter, TH Finnegan, DC AF Deems, Jeffrey S. Painter, Thomas H. Finnegan, David C. TI Lidar measurement of snow depth: a review SO JOURNAL OF GLACIOLOGY LA English DT Review ID AIRBORNE LIDAR; GRAIN-SIZE; HYPERSPECTRAL ANALYSIS; MOUNTAIN CATCHMENT; ERROR BUDGET; COVERED AREA; RETRIEVAL; REFLECTANCE; ACCURACY; ALBEDO AB Laser altimetry (lidar) is a remote-sensing technology that holds tremendous promise for mapping snow depth in snow hydrology and avalanche applications. Recently lidar has seen a dramatic widening of applications in the natural sciences, resulting in technological improvements and an increase in the availability of both airborne and ground-based sensors. Modern sensors allow mapping of vegetation heights and snow or ground surface elevations below forest canopies. Typical vertical accuracies for airborne datasets are decimeter-scale with order 1 m point spacings. Ground-based systems typically provide millimeter-scale range accuracy and sub-meter point spacing over 1 m to several kilometers. Many system parameters, such as scan angle, pulse rate and shot geometry relative to terrain gradients, require specification to achieve specific point coverage densities in forested and/or complex terrain. Additionally, snow has a significant volumetric scattering component, requiring different considerations for error estimation than for other Earth surface materials. We use published estimates of light penetration depth by wavelength to estimate radiative transfer error contributions. This paper presents a review of lidar mapping procedures and error sources, potential errors unique to snow surface remote sensing in the near-infrared and visible wavelengths, and recommendations for projects using lidar for snow-depth mapping. C1 [Deems, Jeffrey S.] Univ Colorado, Natl Snow & Ice Data Ctr, NOAA Western Water Assessment, Boulder, CO 80309 USA. [Painter, Thomas H.] CALTECH, Jet Prop Lab, Pasadena, CA USA. [Finnegan, David C.] US Army Corps Engineers, Cold Reg Res & Engn Lab, Engn Res Ctr, Hanover, NH USA. [Finnegan, David C.] US Army Corps Engineers, Cold Reg Res & Engn Lab, Dev Ctr, Hanover, NH USA. RP Deems, JS (reprint author), Univ Colorado, Natl Snow & Ice Data Ctr, NOAA Western Water Assessment, Boulder, CO 80309 USA. EM deems@nsidc.org RI Painter, Thomas/B-7806-2016; Deems, Jeffrey/E-6484-2016 OI Deems, Jeffrey/0000-0002-3265-8670 FU National Snow and Ice Data Center; national Oceanic and Atmospheric Administration (NOAA) Western Water Assessment; Cooperative Institute for Research in Environmental Sciences (CIRES) Innovative Research Project grant; NASA FX Part of this work was supported by the National Snow and Ice Data Center, the national Oceanic and Atmospheric Administration (NOAA) Western Water Assessment and a Cooperative Institute for Research in Environmental Sciences (CIRES) Innovative Research Project grant. Part of this work was performed at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with NASA. Part of this work was performed at the US Army Corps of Engineers, Cold Regions Research and Engineering Laboratory, Hanover, NH. NR 78 TC 61 Z9 61 U1 14 U2 69 PU INT GLACIOL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE CB2 1ER, ENGLAND SN 0022-1430 EI 1727-5652 J9 J GLACIOL JI J. Glaciol. PY 2013 VL 59 IS 215 BP 467 EP 479 DI 10.3189/2013JoG12J154 PG 13 WC Geography, Physical; Geosciences, Multidisciplinary SC Physical Geography; Geology GA 202BX UT WOS:000323189600006 ER PT J AU Hu, ZZ Vatamanu, J Borodin, O Bedrov, D AF Hu, Zongzhi Vatamanu, Jenel Borodin, Oleg Bedrov, Dmitry TI A molecular dynamics simulation study of the electric double layer and capacitance of [BMIM][PF6] and [BMIM][BF4] room temperature ionic liquids near charged surfaces SO PHYSICAL CHEMISTRY CHEMICAL PHYSICS LA English DT Article ID DENSITY-FUNCTIONAL THEORY; DIFFERENTIAL CAPACITANCE; POLYMER ELECTROLYTES; 2-DIMENSIONAL PERIODICITY; 3-DIMENSIONAL SYSTEMS; GRAPHITE-ELECTRODES; CARBON NANOTUBES; THERMAL-STABILITY; POISSON-BOLTZMANN; CONTACT CONDITION AB A molecular dynamics simulation study of electric double layer (EDL) structure and differential capacitance (DC) of two 1-butyl-3-methylimidazolium (BMIM)-based room temperature ionic liquids, i.e. [BMIM][BF4] and [BMIM][PF6], has been conducted on basal and prismatic graphite as well as (001) and (011) gold electrode surfaces. The influence of the electrode surface and electrolyte structure on electrode capacitance and EDL structure are discussed. For a given electrode surface both the [BMIM][BF4] and [BMIM][PF6] electrolytes generate very similar DC and EDL structures. The DC for these ionic liquids in contact with atomically flat surfaces (i.e. basal graphite and (001)Au) shows very small variations within the electrolyte chemical stability potential window and fluctuates around an average value of similar to 5 mu F cm(-2). On atomically more corrugated surfaces (i.e., Au(011) and prismatic graphite) the DC shows more variation with electrode potential and depends on the correspondence between dimensions of the surface roughness and electrolyte ion sizes. The trends and dependencies obtained for DC are used to discriminate between mutually contradictory experimental data reported in the literature for related systems. C1 [Hu, Zongzhi; Vatamanu, Jenel; Bedrov, Dmitry] Univ Utah, Dept Mat Sci & Engn, Salt Lake City, UT 84112 USA. [Borodin, Oleg] Army Res Lab, Electrochem Branch, Adelphi, MD 20783 USA. RP Vatamanu, J (reprint author), Univ Utah, Dept Mat Sci & Engn, 122 S Cent Campus Dr, Salt Lake City, UT 84112 USA. EM jenel.vatamanu@utah.edu RI Borodin, Oleg/B-6855-2012; Vatamanu, Jenel/I-7638-2012 OI Borodin, Oleg/0000-0002-9428-5291; Vatamanu, Jenel/0000-0003-0825-1608 FU Department of Energy [DE-SC0001912] FX The authors are grateful to the Department of Energy for financial support under the grant DE-SC0001912 to the University of Utah. NR 156 TC 33 Z9 33 U1 8 U2 106 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 1463-9076 J9 PHYS CHEM CHEM PHYS JI Phys. Chem. Chem. Phys. PY 2013 VL 15 IS 34 BP 14234 EP 14247 DI 10.1039/c3cp51218e PG 14 WC Chemistry, Physical; Physics, Atomic, Molecular & Chemical SC Chemistry; Physics GA 195SX UT WOS:000322725000011 PM 23873305 ER PT J AU Steffen, A Bottenheim, J Cole, A Douglas, TA Ebinghaus, R Friess, U Netcheva, S Nghiem, S Sihler, H Staebler, R AF Steffen, A. Bottenheim, J. Cole, A. Douglas, T. A. Ebinghaus, R. Friess, U. Netcheva, S. Nghiem, S. Sihler, H. Staebler, R. TI Atmospheric mercury over sea ice during the OASIS-2009 campaign SO ATMOSPHERIC CHEMISTRY AND PHYSICS LA English DT Article ID SOURCE-RECEPTOR RELATIONSHIPS; ARCTIC-OCEAN; SPRINGTIME DEPLETION; GASEOUS MERCURY; POLAR SUNRISE; NY-ALESUND; DERIVE INFORMATION; ELEMENTAL MERCURY; CRYSTAL-FORMATION; OZONE DEPLETION AB Measurements of gaseous elemental mercury (GEM), reactive gaseous mercury (RGM) and particulate mercury (PHg) were collected on the Beaufort Sea ice near Barrow, Alaska, in March 2009 as part of the Ocean-Atmosphere-Sea Ice-Snowpack (OASIS) and OASIS-Canada International Polar Year programmes. These results represent the first atmospheric mercury speciation measurements collected on the sea ice. Concentrations of PHg averaged 393.5 pg m(-3) (range 47.1-900.1 pg m(-3)) and RGM concentrations averaged 30.1 pg m(-3) (range 3.5-105.4 pg m(-3)) during the two-week-long study. The mean concentration of GEM during the study was 0.59 ng m(-3) (range 0.01-1.51 ng m(-3)) and was depleted compared to annual Arctic ambient boundary layer concentrations. It is shown that when ozone (O-3) and bromine oxide (BrO) chemistry were active there is a positive linear relationship between GEM and O-3, a negative one between PHg and O-3, a positive correlation between RGM and BrO, and none between RGM and O-3. For the first time, GEM was measured simultaneously over the tundra and the sea ice. The results show a significant difference in the magnitude of the emission of GEM from the two locations, with significantly higher emission over the tundra. Elevated chloride levels in snow over sea ice are proposed to be the cause of lower GEM emissions over the sea ice because chloride has been shown to suppress photoreduction processes of RGM to GEM in snow. Since the snowpack on sea ice retains more mercury than inland snow, current models of the Arctic mercury cycle may greatly underestimate atmospheric deposition fluxes because they are based predominantly on land-based measurements. Land-based measurements of atmospheric mercury deposition may also underestimate the impacts of sea ice changes on the mercury cycle in the Arctic. The predicted changes in sea ice conditions and a more saline future snowpack in the Arctic could enhance retention of atmospherically deposited mercury and increase the amount of mercury entering the Arctic Ocean and coastal ecosystems. C1 [Steffen, A.; Bottenheim, J.; Cole, A.; Netcheva, S.; Staebler, R.] Environm Canada, Air Qual Proc Res Sect, Toronto, ON M3H 5T4, Canada. [Steffen, A.; Ebinghaus, R.] Univ Luneburg, ISEC, D-21335 Luneburg, Germany. [Douglas, T. A.] US Army Cold Reg Res & Engn Lab, Ft Wainwright, AK 99703 USA. [Ebinghaus, R.] Helmholtz Zentrum Geesthacht, Inst Coastal Res, Dept Environm Chem, D-21502 Geesthacht, Germany. [Friess, U.; Sihler, H.] Heidelberg Univ, Inst Environm Phys, D-69120 Heidelberg, Germany. [Nghiem, S.] CALTECH, Jet Prop Lab, Pasadena, CA USA. RP Steffen, A (reprint author), Environm Canada, Air Qual Proc Res Sect, 4905 Dufferin St, Toronto, ON M3H 5T4, Canada. EM alexandra.steffen@ec.gc.ca OI Cole, Amanda/0000-0002-5434-4998 FU Environment Canada; Canadian International Polar Year programme; US National Science Foundation; US National Aeronautics and Space Administration; National Aeronautics and Space Administration (NASA) Cryospheric Sciences Program FX The authors would like to thank Environment Canada and the Canadian International Polar Year programme for funding this project. T. Douglas acknowledges instrumentation support from the US Army Cold Regions Research and Engineering Laboratory and financial support from the US National Science Foundation and the US National Aeronautics and Space Administration. Logistical support in Barrow was provided by the Barrow Arctic Science Consortium. The authors thank Patrick Lee for field technical support and Julie Narayan for data analysis support. The research carried out at the Jet Propulsion Laboratory, California Institute of Technology, was supported by the National Aeronautics and Space Administration (NASA) Cryospheric Sciences Program. NR 68 TC 13 Z9 13 U1 1 U2 30 PU COPERNICUS GESELLSCHAFT MBH PI GOTTINGEN PA BAHNHOFSALLEE 1E, GOTTINGEN, 37081, GERMANY SN 1680-7316 J9 ATMOS CHEM PHYS JI Atmos. Chem. Phys. PY 2013 VL 13 IS 14 BP 7007 EP 7021 DI 10.5194/acp-13-7007-2013 PG 15 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA 191XL UT WOS:000322448300018 ER PT J AU Rider, T AF Rider, Thomas BE McDonald, RMS TI SON OF THE ARMY Captain Robert Kirkwood of the Delaware Regiment SO SONS OF THE FATHER: GEORGE WASHINGTON AND HIS PROTEGES LA English DT Article; Book Chapter C1 [Rider, Thomas] US Mil Acad, West Point, NY USA. NR 25 TC 0 Z9 0 U1 0 U2 0 PU UNIV PRESS VIRGINIA PI CHARLOTTESVILLE PA P O BOX 400318,, CHARLOTTESVILLE, VA 22904-4318 USA BN 978-0-8139-3439-6 PY 2013 BP 232 EP 256 PG 25 WC History SC History GA BFT54 UT WOS:000321251500013 ER PT S AU Gurram, P Hu, SW Chan, A AF Gurram, Prudhvi Hu, Shuowen Chan, Alex BE Baskurt, AM Sitnik, R TI Uniform Grid Upsampling of 3D LiDAR Point Cloud Data SO THREE-DIMENSIONAL IMAGE PROCESSING (3DIP) AND APPLICATIONS 2013 SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Three-Dimensional Image Processing (3DIP) and Applications CY FEB 06-07, 2013 CL Burlingame, CA SP Soc Imaging Sci & Technol (IS&T), SPIE, Qualcomm Inc DE 3D point cloud data; LiDAR data; uniform grid sampling; image inpainting; Cahn-Hilliard PDE ID MODEL AB Airborne laser scanning light detection and ranging (LiDAR) systems are used for remote sensing topology and bathymetry. The most common data collection technique used in LiDAR systems employs a linear mode scanning. The resulting scanning data form a non-uniformly sampled 3D point cloud. To interpret and further process the 3D point cloud data, these raw data are usually converted to digital elevation models (DEMs). In order to obtain DEMs in a uniform and upsampled raster format, the elevation information from the available non-uniform 3D point cloud data are mapped onto the uniform grid points. After the mapping is done, the grid points with missing elevation information are filled by using interpolation techniques. In this paper, partial differential equations (PDE) based approach is proposed to perform the interpolation and to upsample the 3D point cloud onto a uniform grid. Due to the desirable effects of using higher order PDEs, smoothness is maintained over homogeneous regions, while sharp edge information in the scene well preserved. The proposed algorithm reduces the draping effects near the edges of distinctive objects in the scene. Such annoying draping effects are commonly associated with existing point cloud rendering algorithms. Simulation results are presented in this paper to illustrate the advantages of the proposed algorithm. C1 [Gurram, Prudhvi; Hu, Shuowen; Chan, Alex] Army Res Lab, ATTN RDRL SES E, Adelphi, MD 20783 USA. RP Gurram, P (reprint author), Army Res Lab, ATTN RDRL SES E, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM pkgurram@gmail.com; shuowen.hu.civ@mail.mil; alex.l.chan.civ@mail.mil NR 18 TC 0 Z9 0 U1 0 U2 7 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9423-8 J9 PROC SPIE PY 2013 VL 8650 AR 86500B DI 10.1117/12.2004200 PG 11 WC Optics; Imaging Science & Photographic Technology SC Optics; Imaging Science & Photographic Technology GA BGA80 UT WOS:000322110500009 ER PT B AU Bindel, SR AF Bindel, Scott R. GP IEEE TI Optimizing Test Confidence Based on Life Cycle Cost SO 59TH ANNUAL RELIABILITY AND MAINTAINABILITY SYMPOSIUM (RAMS) LA English DT Proceedings Paper CT 59th Annual Reliability and Maintainability Symposium (RAMS) CY JAN 28-31, 2013 CL Orlando, FL SP IIE, IEST, AIAA, IEEE Reliabil Soc, SAE Int, Soc Reliabil Engineers (SRE), SSS, ASQ, Elect & Commun Div, ASQ, Reliabil Div DE Life cycle cost; LCC; O&S cost; test confidence; reliability; requirements development; RAM AB Current Army acquisition policy states that systems shall demonstrate reliability requirements with high confidence, but the policy fails to state what 'high' confidence means. Despite this, for every system there is an optimal confidence level with which to demonstrate the reliability requirement. The optimal confidence level may be driven by many competing factors including cost, schedule, Soldier safety, and mission criticality. Most of these factors are difficult to quantify, and leave the community to make a judgment call on the appropriate confidence level. In the absence of other driving or quantifiable metrics, one way to choose an optimal confidence level is to balance test cost against the risk to life cycle cost. This method deals in a natural metric: money. It is easily understood by the layman, and is straightforward to compare to most other programmatic risks. Conveniently it provides objective support for the common sense solution that inexpensive systems (to buy and test) that will be purchased in large quantities should be tested at higher confidence, while expensive systems (to buy and test) bought in low quantities possibly should be tested at lower confidence. If the other factors are not overwhelming, or do not suggest a particular confidence level, confidence can be optimized by balancing test cost against life cycle cost. C1 US Army, Test & Evaluat Command, Aberdeen Proving Ground, MD 21005 USA. RP Bindel, SR (reprint author), US Army, Test & Evaluat Command, 2202 Aberdeen Blvd, Aberdeen Proving Ground, MD 21005 USA. EM scott.bindel@us.army.mil NR 1 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-4711-2 PY 2013 PG 5 WC Engineering, Industrial; Engineering, Electrical & Electronic; Operations Research & Management Science SC Engineering; Operations Research & Management Science GA BFW62 UT WOS:000321693500153 ER PT J AU Habtour, E Werner, B Hilburn, A Saraidaridis, HI AF Habtour, Ed Werner, Benjamin Hilburn, Adam Saraidaridis, Harry I. GP IEEE TI Physics of Failure for Portable Electronic Devices in Military Applications SO 59TH ANNUAL RELIABILITY AND MAINTAINABILITY SYMPOSIUM (RAMS) LA English DT Proceedings Paper CT 59th Annual Reliability and Maintainability Symposium (RAMS) CY JAN 28-31, 2013 CL Orlando, FL SP IIE, IEST, AIAA, IEEE Reliabil Soc, SAE Int, Soc Reliabil Engineers (SRE), SSS, ASQ, Elect & Commun Div, ASQ, Reliabil Div DE drop; failure mechanism; handheld; Physics of Failure AB In military applications electronic devices play a vital role in the success of a mission. These devices which provide control, guidance, communication, and reconnaissance are critical components in modern unmanned vehicular applications. The current trend is to provide a human interface to control theses systems via portable devices. This trend in modern warfare has increased the complexity of electronic equipment, especially in low volume, highly sophisticated, and dense electronic systems. These modern devices take advantage of the remarkable advances made in low cost commercial electronics. This current movement of using commercial-off-the-shelf (COTS) electronics and devices for military applications has led to concerns about their reliability in harsh battlefield environments. The increase in the use of COTS components lead to the need to improve the reliability of these components by understanding the failure mechanisms due to thermal loads, dynamic vibration, and shock through Physics of Failure (PoF) analyses. Unfortunately, current military standards do not provide an adequate approach to analyze, design, or test for those types of complex portable electronic systems. In some cases, the loading profiles may be over-conservative and in others under-conservative and not representative of the operational conditions. In this paper, a PoF approach is provided to understand the failure mechanisms experienced by these devices during their life-cycle. In this study, the life-cycle of portable handheld electronic device was modeled. The life-cycle included thermal loading from diurnal cycles and power cycles and vibration loads due to transportation.. The transient response of electronic assemblies to mechanical loading encountered in drop and shock conditions was simulated. These loads may impose significant stresses on the Printed Circuit Board (PCB) substrate, component packages, leads, and solder joints. Explicit finite element analysis combined with computational thermal analysis and analytical models have been utilized to uncover potential failure modes. To reduce the computational time and cost, modified shell elements were used to model the circuit card assemblies (CCAs). Failure modes predicted by the modeling and simulation were utilized to assess the overall reliability of the portable device. This study demonstrates how a PoF approach may provide an understanding of the loads experienced by the electronics and how they affect the reliability of the device. This is critical to developing and acquiring more reliable systems as the DoD begins to utilize more advanced portable electronics systems. C1 [Habtour, Ed] ARL, Vehicle Technol Directorate, Aberdeen Proving Ground, MD 21005 USA. RP Habtour, E (reprint author), ARL, Vehicle Technol Directorate, Aberdeen Proving Ground, MD 21005 USA. EM ed.m.habtour.civ@mail.mil; benjamin.d.werner2.civ@mail.mil; hsaraidaridis@irobot.com NR 8 TC 0 Z9 0 U1 1 U2 11 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-4711-2 PY 2013 PG 6 WC Engineering, Industrial; Engineering, Electrical & Electronic; Operations Research & Management Science SC Engineering; Operations Research & Management Science GA BFW62 UT WOS:000321693500005 ER PT B AU Hunt, EE Wester, JA AF Hunt, Eric E. Wester, James A. GP IEEE TI Optimizing the Non-Destructive Test Program for a Missile Inventory SO 59TH ANNUAL RELIABILITY AND MAINTAINABILITY SYMPOSIUM (RAMS) LA English DT Proceedings Paper CT 59th Annual Reliability and Maintainability Symposium (RAMS) CY JAN 28-31, 2013 CL Orlando, FL SP IIE, IEST, AIAA, IEEE Reliabil Soc, SAE Int, Soc Reliabil Engineers (SRE), SSS, ASQ, Elect & Commun Div, ASQ, Reliabil Div DE missile surveillance; missile non-destructive test; stockpile reliability program AB The quantity and frequency of non-destructive testing (NDT) across the life cycle of a missile inventory must be carefully considered. This paper provides a process for optimizing the quantity of missiles subject to NDT across the life of the missile inventory. This process ensures that the program does not exceed the minimum test quantity necessary to ensure that the inventory continues to meet the user's reliability requirement based on the predicted failure probability and annual test quantity. The methodology takes into account the age distribution of the inventory, tested/untested populations, removal of failing hardware, and items with multiple tests through the system life. The analysis also provides an estimate of the minimum and maximum test time that missiles will be exposed to across the projected life of the inventory. The paper provides an example of the process as applied to a representative Army missile system. This example demonstrates the practicality and simplicity of the process. The affect of varying levels of NDT on the inventory reliability is readily apparent in graphical form that facilitates the Reliability Engineer in presenting options to the Program Manager for making sustainment decisions. Overall, the U. S. Army Stockpile Reliability Program (SRP) has repeatedly demonstrated successes in identifying trends, ensuring readiness, and justifying missile shelf life extensions. However, under the current era of decreasing defense budgets, and expectations to push the life of existing missile systems out without replacement, NDT costs should be minimized while simultaneously minimizing the wear of those tests on the inventory. The approach outlined in this paper can be used to accomplish this on either the existing NDT program for a fielded system, or by the Program Manager developing a SRP program plan for a new missile system. C1 [Hunt, Eric E.; Wester, James A.] US Army RDECOM, RDMR SER, Redstone Arsenal, AL 35898 USA. RP Hunt, EE (reprint author), US Army RDECOM, RDMR SER, Redstone Arsenal, AL 35898 USA. EM eric.hunt1@us.army.mil; James.Wester@msl.army.mil NR 1 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-4711-2 PY 2013 PG 6 WC Engineering, Industrial; Engineering, Electrical & Electronic; Operations Research & Management Science SC Engineering; Operations Research & Management Science GA BFW62 UT WOS:000321693500133 ER PT J AU Payne, RS AF Payne, Richard S. GP IEEE TI A Practical Approach to Software Reliability for Army Systems SO 59TH ANNUAL RELIABILITY AND MAINTAINABILITY SYMPOSIUM (RAMS) LA English DT Proceedings Paper CT 59th Annual Reliability and Maintainability Symposium (RAMS) CY JAN 28-31, 2013 CL Orlando, FL SP IIE, IEST, AIAA, IEEE Reliabil Soc, SAE Int, Soc Reliabil Engineers (SRE), SSS, ASQ, Elect & Commun Div, ASQ, Reliabil Div DE Software Reliability; Defect Elimination; Failure Definition Scoring Criteria; Mission Critical Requirements AB The objective of this paper on Software Reliability (SWR) is to provide a practical approach to implementing a SWR program for Army software intensive system acquisition planning and subsequent software development activities. The goal of this paper will be to leave the reader with the understanding that there is no magic to implement a robust SWR strategy and also to show that there is an abundance of information available from a myriad of industry sources on the subject. I don't intend to list those sources here; the reader can just do an internet search. The point I am making is that like any good "Bootlegger", my intent is to "distill" various ingredients, in this case, industry knowledge on software reliability and adopt a strategy that bests suits my particular organization. This strategy can be adopted in its entirety or tweaked to suit specific organizational needs. Regardless of any strategy that is adopted, it is critical that appropriate statement of work or contract language needs to be specified when acquiring software from a supplier or developing it from an in-house source. Finally, like any idea this one needs a home. There were Software Reliability requirements in the Software Development Plan of a large, now cancelled, software intensive Army program but the requirements were nebulous and some of the reference documents were out of date. Unfortunately, a good number of software problems ultimately labeled "Software Reliability defects" caused both formal laboratory and field testing delays. A robust SWR program may have avoided those costly rework efforts and delays. Unlike System Safety (incl Software) (MIL-STD-882E) or Information Assurance Certification (DIACAP), there is no official mandate or specific policy for Software Reliability Process compliance for Army Programs. However, I did manage to defend getting SWR contract language into the Ground Combat Systems contract. It called for collaboration between software and reliability subject matter experts to take appropriate steps to include software into the reliability case for the system. I also managed to obtain one fulltime equivalent work year of SWR engineering support to the Program. It was like planting a seed and the fruits of this labor are yet to be realized but progress has been made. C1 US Army, ARDEC, Picatinny Arsenal, NJ 07806 USA. RP Payne, RS (reprint author), US Army, ARDEC, RDAR QEW F Bldg 62, Picatinny Arsenal, NJ 07806 USA. EM Richard.s.payne.civ@mail.mil NR 6 TC 0 Z9 0 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-4711-2 PY 2013 PG 5 WC Engineering, Industrial; Engineering, Electrical & Electronic; Operations Research & Management Science SC Engineering; Operations Research & Management Science GA BFW62 UT WOS:000321693500094 ER PT B AU Ray, DM Golden, ES Drake, C AF Ray, Douglas M. Golden, Eli S. Drake, Christopher GP IEEE TI Sensitivity Testing and Logit Analysis: Two Recent Armaments Engineering Case-Studies SO 59TH ANNUAL RELIABILITY AND MAINTAINABILITY SYMPOSIUM (RAMS) LA English DT Proceedings Paper CT 59th Annual Reliability and Maintainability Symposium (RAMS) CY JAN 28-31, 2013 CL Orlando, FL SP IIE, IEST, AIAA, IEEE Reliabil Soc, SAE Int, Soc Reliabil Engineers (SRE), SSS, ASQ, Elect & Commun Div, ASQ, Reliabil Div DE Binary Logistic Regression; Logit Analysis; Design of Experiments; Sequential Testing; D-Optimal; Quantal Response-Curve ID DESIGNS AB Efficient statistical techniques for designing and analyzing experiments are often misunderstood or underutilized, despite possessing great potential when well-informed decision-making and significant cost-savings are desired. Destructive testing with binary response data is a 'worst-case' scenario with regards to cost and efficiency; however, in armaments engineering (especially with explosives, energetic mixes, propellants, pyrotechnics, and other one-shot devices) binary response data is often all that is available. This paper illustrates modern methods and best-practices to employ when dealing with these types of analyses, and contrasts two very different types of testing strategies applied to the munitions used in training and battle by the Warfighter. First, we introduce the topic of test design and experimentation. To motivate the subject and illustrate some basic aspects of sensitivity testing, we present an example common to the general public: impact-resistant cases for smart-phones. Next, we elaborate on some of the finer details of Logit Analysis/Binary Logistic Regression and Generalized Linear Models (GLM), while highlighting some of the mathematical underpinnings inherent in these methods. An overview of testing strategies follows, which compares some of the different methods available for data generation. These methods can be roughly divided into two groups - those dealing with pre-manufactured test samples, and those where sequential testing is an option. Sequential tests are generally applicable when the stress level of interest is adjustable during the test's execution, which, with regard to sample size, allows for a more efficient test. Then we detail two recent successful examples in armament munitions testing: one where sequential testing was not possible (9mm ammunition propellant critical threshold development), and one where sequential testing was utilized (NMT - Networked Munition Technology). Finally, we discuss some best-practices, limitations, and rules-of-thumb to be mindful of when considering these methods for different applications. C1 [Ray, Douglas M.; Golden, Eli S.] US Army RDECOM ARDEC, Stat Methods & Anal Grp, QE&SA Reliabil Management Branch, Picatinny Arsenal, NJ 07806 USA. RP Ray, DM (reprint author), US Army RDECOM ARDEC, Stat Methods & Anal Grp, QE&SA Reliabil Management Branch, Bldg 92, Picatinny Arsenal, NJ 07806 USA. EM douglas.m.ray.civ@mail.mil; eli.s.golden.civ@mail.mil; christopher.drake4.civ@mail.mil NR 8 TC 0 Z9 0 U1 1 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-4711-2 PY 2013 PG 5 WC Engineering, Industrial; Engineering, Electrical & Electronic; Operations Research & Management Science SC Engineering; Operations Research & Management Science GA BFW62 UT WOS:000321693500028 ER PT B AU Agrawal, H Bowen, TF Narain, S AF Agrawal, Hira Bowen, Thomas F. Narain, Sanjai BE Hsu, DF Marinucci, D TI Defending Software Systems against Cyber Attacks throughout Their Lifecycle SO ADVANCES IN CYBER SECURITY: TECHNOLOGY, OPERATIONS, AND EXPERIENCES LA English DT Article; Book Chapter RP Agrawal, H (reprint author), US Army, CERDEC Project, Adelphi, MD 20783 USA. NR 21 TC 0 Z9 0 U1 0 U2 0 PU FORDHAM UNIV PRESS PI BRONX PA UNIV BOX L, BRONX, NY 10458 USA BN 978-0-8232-4456-0 PY 2013 BP 74 EP 89 PG 16 WC Computer Science, Theory & Methods SC Computer Science GA BFJ42 UT WOS:000320106300005 ER PT J AU Campbell, S Roy, S Kreutz, K Arcone, SA Osterberg, EC Koons, P AF Campbell, Seth Roy, Samuel Kreutz, Karl Arcone, Steven A. Osterberg, Erich C. Koons, Peter TI Strain-rate estimates for crevasse formation at an alpine ice divide: Mount Hunter, Alaska SO ANNALS OF GLACIOLOGY LA English DT Article ID KAHILTNA GLACIER; FLOW DYNAMICS; ANTARCTICA; RADAR; STRATIGRAPHY; RANGE AB Crevasse initiation is linked to strain rates that range over three orders of magnitude (0.001 and 0.163 a(-1)) as a result of the temperature-dependent nonlinear rheological properties of ice and from water and debris inclusions. Here we discuss a small cold glacier that contains buried crevasses at and near an ice divide. Surface-conformable stratigraphy, the glacier's small size, and cold temperatures argue for limited rheological variability at this site. Surface ice-flow velocities of (1.2-15.5) +/- 0.472 m a(-1) imply classic saddle flow surrounding the ice divide. Numerical models that incorporate field-observed boundary conditions suggest extensional strain rates of 0.003-0.015 a(-1), which fall within the published estimates required for crevasse initiation. The occurrence of one crevasse beginning at 50 m depth that appears to penetrate close to the bed suggests that it formed at depth. Field data and numerical models indicate that a higher interior stress at this crevasse location may be associated with steep convex bed topography; however, the dynamics that caused its formation are not entirely clear. C1 [Campbell, Seth; Roy, Samuel; Kreutz, Karl; Koons, Peter] Univ Maine, Orono, ME USA. [Campbell, Seth; Arcone, Steven A.] US Army, Cold Reg Res & Engn Lab, Hanover, NH USA. [Osterberg, Erich C.] Dartmouth Coll, Dept Earth Sci, Hanover, NH 03755 USA. RP Campbell, S (reprint author), Univ Maine, Orono, ME USA. EM seth.campbell@umit.maine.edu FU Denali National Park Murie Science and Learning Center Fellowship; Dan and Betty Churchill Exploration Fund; American Alpine Club FX We thank David Vaughan for helpful comments during the initial stages of the manuscript and Gordon Hamilton for assistance with GPS uncertainty analysis. Funding was provided by the American Alpine Club, Denali National Park Murie Science and Learning Center Fellowship, and the Dan and Betty Churchill Exploration Fund. We also thank the University of Maine, Dartmouth College, the US Army CRREL, Denali National Park and Preserve, Talkeetna Air Taxi, John Thompson and Dominic Winski for providing equipment and field support. Nate Lamie, Steven Decato and Jesse Stanley (CRREL) also provided significant technical support prior to and following field seasons. NR 20 TC 0 Z9 0 U1 2 U2 16 PU INT GLACIOL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE CB2 1ER, ENGLAND SN 0260-3055 EI 1727-5644 J9 ANN GLACIOL JI Ann. Glaciol. PY 2013 VL 54 IS 63 BP 200 EP 208 DI 10.3189/2013AoG63A266 PN 2 PG 9 WC Geography, Physical; Geosciences, Multidisciplinary SC Physical Geography; Geology GA 186MA UT WOS:000322047200003 ER PT J AU Lensu, M Elder, BC Richter-Menge, J Haapala, J AF Lensu, Mikko Elder, Bruce C. Richter-Menge, Jackie Haapala, Jari TI Comparison of ice stress records in terms of extreme value analysis SO ANNALS OF GLACIOLOGY LA English DT Article ID SEA-ICE; PACK ICE; DEFORMATION; MODEL AB Dynamic ice models use stress tensor to describe the forces arising from internal ice friction. The model stress values are typically one to two magnitudes smaller than values measured by stressmeters deployed on ice floes. The synthesis of the pack-ice stress state from the measurements has been complicated by the peaky character of stress records, and the means to connect them with spatial stress distribution of the floe system have been lacking. Here a reanalysis of Arctic Sea Ice Mechanics Initiative (SIMI) data is made in terms of extreme value statistics. The basic quantity is the maximum stress observed during a time period. The records exhibit self-affine scaling. The statistics are then determined by two parameters, the Hurst exponent H and a reference stress level. Similar analysis is possible for the kinematic data. This establishes the comparability of stress records with each other and with kinematic records. The results suggest that the exponent is related to the stress state of the regional floe system, while the stress level is determined by local floe characteristics. Based on this a characterization of spatial distribution of pack-ice stresses is given. C1 [Lensu, Mikko; Haapala, Jari] Finnish Meteorol Inst, FIN-00101 Helsinki, Finland. [Elder, Bruce C.; Richter-Menge, Jackie] USACE Engineer Res & Dev Ctr, Cold Reg Res & Engn Lab, Hanover, NH USA. RP Lensu, M (reprint author), Finnish Meteorol Inst, FIN-00101 Helsinki, Finland. EM mikko.lensu@fmi.fi FU European Union [SCP8-GA-2009-233884-SAFEWIN] FX This research was conducted within the European Union-funded projects 'Safety of winter navigation in dynamic ice' (contract SCP8-GA-2009-233884-SAFEWIN). The partners in this project are Aalto University, the Arctic and Antarctic Research Institute, the Finnish Meteorological Institute, the Finnish Transport Agency, ILS Oy, Stena Rederi AB, the Swedish Maritime Administration, the Swedish Meteorological and Hydrological Institute, Tallinn University of Technology and the AS Tallink Group. The open access to US Army Cold Regions Research and Engineering Laboratory (CRREL) stress data is greatly appreciated. NR 21 TC 0 Z9 0 U1 0 U2 4 PU INT GLACIOL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE CB2 1ER, ENGLAND SN 0260-3055 J9 ANN GLACIOL JI Ann. Glaciol. PY 2013 VL 54 IS 62 BP 291 EP 298 DI 10.3189/2013AoG62A194 PN 2 PG 8 WC Geography, Physical; Geosciences, Multidisciplinary SC Physical Geography; Geology GA 186LZ UT WOS:000322047100020 ER PT S AU Jones, TL Kondoh, K Mimoto, T Nakanishi, N Umeda, J AF Jones, Tyrone L. Kondoh, Katsuyoshi Mimoto, Takanori Nakanishi, Nozomi Umeda, Junko BE Imam, MA Froes, FHS Reddy, RG TI The Development of a Ti-6Al-4V Alloy via Oxygen Solid Solution Strengthening for Aerospace & Defense Applications SO COST-AFFORDABLE TITANIUM IV SE Key Engineering Materials LA English DT Proceedings Paper CT Symposium on Cost Affordable Titanium 4 at the 142nd TMS Annual Meeting and Exhibition CY MAR 03-07, 2013 CL San Antonio, TX SP TMS, Structural Mat Div, TMS, Titanium Comm DE titanium alloys; Ti-6Al-4V; ballistic performance; cost affordable; TiO2 AB The high cost of titanium has historically prevented widespread use in military ground vehicles. Two strategies to make this material more cost effective and viable are to reduce the cost of titanium armors or to improve the ballistic performance of titanium and reduce the amount of material required. This paper investigates the latter strategy. Mixtures of titanium powders and TiO2 particles were employed as starting materials and consolidated by spark plasma sintering (SPS) and hot extrusion. The content of TiO2 particles was 0 similar to 1.5% of the mass mixture. Solidification of oxygen atoms (from TiO2 particles) into Ti matrix occurred at 1073K for 1800 seconds in a vacuum. Tensile testing showed that Tensile Strength (TS) and Yield Strength (YS) increased in proportion to TiO2 content but elongation decreased slightly with increased TiO2 content. Extruded pure Ti powder material with 1.5% TiO2 particles produced 1040 MPa TS, 902 MPa YS and 25.1% elongation when tested. When using Ti-6Al-4V (Ti-64) alloy powders with 0.5% TiO2 particles, the final extruded Ti-64 powder bars with oxygen solid solution showed 1226 MPa TS and 22.7% elongation. Initial ballistic evaluation showed the Ti-64 powder bars with 0.5% TiO2 particles yielded a marked improvement over the conventionally rolled Ti-64 alloy plate. C1 [Jones, Tyrone L.] US Army Res Lab, Aberdeen Proving Ground, MD USA. RP Jones, TL (reprint author), US Army Res Lab, Aberdeen Proving Ground, MD USA. EM tyrone.jones6@us.army.mil; kondoh@jwri.osaka-u.ac.jp NR 10 TC 1 Z9 1 U1 3 U2 9 PU TRANS TECH PUBLICATIONS LTD PI STAFA-ZURICH PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND SN 1013-9826 J9 KEY ENG MATER PY 2013 VL 551 BP 118 EP 126 DI 10.4028/www.scientific.net/KEM.551.118 PG 9 WC Metallurgy & Metallurgical Engineering SC Metallurgy & Metallurgical Engineering GA BFX54 UT WOS:000321795200016 ER PT S AU Chappell, M Middleton, M Price, C AF Chappell, Mark Middleton, Matthew Price, Cynthia BE Hellmann, R Pitsch, H TI Chemical and physical changes in tropical soils from seawater exposure and subsequent rainwater washes SO PROCEEDINGS OF THE FOURTEENTH INTERNATIONAL SYMPOSIUM ON WATER-ROCK INTERACTION, WRI 14 SE Procedia Earth and Planetary Science LA English DT Proceedings Paper CT 14th International Symposium on Water-Rock Interaction (WRI) CY JUN 09-14, 2013 CL Avignon, FRANCE SP Int Assoc Geochemistry, Int Assoc Geochemistry (IAGC), Water Rock Interact Working Grp, French Geol Survey (BRGM), French Alternat Energy & Atom Energy Commiss, French Inst Radioprotect & Nucl Safety (IRSN), US Army Engineer Res & Dev Ctr DE sodic soils; saltwater exposure; climate change AB There is little published information regarding the response of tropical island soils to periodic seawater intrusions. In this paper, we describe batch experiments where samples of three Hawaiian acidic upland soils (collected from western Oahu, Hawaii) were equilibrated for 16 h with simulated seawaters, ranging from 0.25-25 g L-1 (or ppT) of total salt, and then washed three times with 20 mu S cm(-1) solutions containing dilute concentration of NaCl (approx. 0.01 g.L-1) to simulate rainfall events. Solution data showed that the exchangeable sodium (ExNa) loads were high on all soils. While much of this ExNa was lixiviated with the rainwater washes, the soil exhibited significant remaining exchangeable sodium percentages (ESP). Consequences of the residual ESP after intensive washings were exhibited in the enhanced dispersiveness (i.e., increased settling time) of the soil colloids. In balance of the continuous sea spray and lower rainfall of the site, it is likely that high salt, high sodium effects would be manifested for extended periods of time in these soils. (C) 2013 The Authors. Published by Elsevier B.V. C1 [Chappell, Mark; Price, Cynthia] US Army Engineer Res & Dev Ctr, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. [Middleton, Matthew] Badger Tech Serv, Vicksburg, MS 30180 USA. RP Chappell, M (reprint author), US Army Engineer Res & Dev Ctr, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM mark.a.chappell@usace.army.mil NR 9 TC 2 Z9 2 U1 1 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 1878-5220 J9 PROCED EARTH PLAN SC PY 2013 VL 7 BP 131 EP 134 DI 10.1016/j.proeps.2013.03.190 PG 4 WC Geosciences, Multidisciplinary SC Geology GA BFW45 UT WOS:000321664000032 ER PT S AU Cole, B Hays, A McIntosh, C Goldberg, L AF Cole, Brian Hays, Alan McIntosh, Chris Goldberg, Lew BE Clarkson, WA Shori, RK TI Wide temperature operation of a VCSEL pumped 355nm frequency tripled Nd:YAG laser SO SOLID STATE LASERS XXII: TECHNOLOGY AND DEVICES SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on Solid State Lasers XXII - Technology and Devices CY FEB 03-05, 2013 CL San Francisco, CA SP SPIE DE Solid state lasers; Nd:YAG; passive Q-switching AB We have fabricated prototype frequency tripled Nd:YAG lasers using 808nm Vertical Cavity Surface emitting laser (VCSEL) arrays for end-pumping. The passively Q-switched Nd:YAG laser generated 15mJ pulses with a duration of 2-4 ns. Used as a source for third harmonic generation, the laser produced in excess of 2mJ at 355nm. Of particular concern was the impact of temperature variation on conversion efficiency, which included effects for both the source laser and non-linear crystals. Various solutions to the temperature effects were explored to enable operation of the frequency tripled laser over a wide temperature range. C1 [Cole, Brian; Hays, Alan; McIntosh, Chris; Goldberg, Lew] US Army, Night Vis & Elect Sensors Directorate, RDECOM CERDEC, Ft Belvoir, VA 22060 USA. RP Cole, B (reprint author), US Army, Night Vis & Elect Sensors Directorate, RDECOM CERDEC, Ft Belvoir, VA 22060 USA. NR 7 TC 0 Z9 0 U1 1 U2 3 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9368-2 J9 PROC SPIE PY 2013 VL 8599 AR 85991L DI 10.1117/12.2006254 PG 7 WC Engineering, Electrical & Electronic; Optics; Physics, Applied SC Engineering; Optics; Physics GA BFY46 UT WOS:000321895100050 ER PT S AU Pendley, SS Manocchi, AK Baker, DR Sumner, JJ Lundgren, CA Hurley, MM AF Pendley, Scott S. Manocchi, Amy K. Baker, David R. Sumner, James J. Lundgren, Cynthia A. Hurley, Margaret M. BE Fitzgerald, G Govind, N TI Challenges and Development of a Multi-Scale Computational Model for Photosystem I Decoupled Energy Conversion SO APPLICATIONS OF MOLECULAR MODELING TO CHALLENGES IN CLEAN ENERGY SE ACS Symposium Series LA English DT Proceedings Paper CT Symposium on Applications of Computational Methods to Environmentally Sustainable Solutions at ACS National Spring Meeting CY MAR 25-29, 2012 CL San Diego, CA SP ACS, Div Comp Chem DE Photosystem I; cytochrome c(6); computational chemistry; molecular modeling; docking; quantum mechanics; self-assembled monolayer; photoelectrochemistry; electron transfer ID PRIMARY ELECTRON-DONOR; PHOTOSYNTHETIC REACTION CENTERS; CHLAMYDOMONAS-REINHARDTII; CYTOCHROME C(6); SYNECHOCOCCUS-ELONGATUS; HYDROGEN-PRODUCTION; CHLOROPHYLL-A; CRYSTAL-STRUCTURE; EXCITED-STATES; HYBRID COMPLEX AB The light-harvesting and charge-transfer abilities of Photosystem I (PSI) have generated interest in the development of this system for alternative energy production and energy conversion. We describe multi-scale computational approaches that were used to study electron transfer at the PSI-biological and inorganic interfaces and to model this large protein complex. Our work in the development of an all molecular dynamics model of the PSI monomer is shown and compared to the published experimental and ONIOM optimized models with differences noted in protein and ligand structure, electron branch characterization, and ionization and orbital potentials in the P700 chlorophylls. Differences between the docking of cytochrome c(6) and plastocyanin to PSI using established docking algorithms and molecular dynamics are described. Finally, dipole calculations, luminal surface hydropathicity and polarity characterization were used to predict improvements in surface-assembled monolayer design. C1 [Pendley, Scott S.; Hurley, Margaret M.] US Army Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. RP Pendley, SS (reprint author), US Army Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. EM margaret.m.hurley12.civ@mail.mil NR 84 TC 1 Z9 1 U1 0 U2 10 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 SIXTEENTH ST NW, WASHINGTON, DC 20036 USA SN 0097-6156 BN 978-0-8412-2820-7 J9 ACS SYM SER JI ACS Symp. Ser. PY 2013 VL 1133 BP 177 EP 202 PG 26 WC Chemistry, Multidisciplinary; Computer Science, Interdisciplinary Applications; Energy & Fuels SC Chemistry; Computer Science; Energy & Fuels GA BFX60 UT WOS:000321806600010 ER PT J AU Perkins, EJ Garcia-Reyero, N AF Perkins, Edward J. Garcia-Reyero, Natalia BE Fowler, BA TI Computational Translation of Nonmammalian Species Data to Mammalian Species to Meet REACH and Next Generation Risk Assessment Needs SO COMPUTATIONAL TOXICOLOGY: METHODS AND APPLICATIONS FOR RISK ASSESSMENT LA English DT Article; Book Chapter ID BOBWHITE COLINUS-VIRGINIANUS; DIFFERENTIAL GENE-EXPRESSION; MINNOW PIMEPHALES-PROMELAS; ESTROGEN-RECEPTOR-ALPHA; NORTHERN BOBWHITE; RETINOIC ACID; DAPHNIA-MAGNA; PATHWAY ANALYSIS; SYSTEMS BIOLOGY; DRUG TARGETS C1 [Perkins, Edward J.] USA, Engineer Res & Dev Ctr, Vicksburg, MS USA. [Garcia-Reyero, Natalia] Mississippi State Univ, Starkville, MS USA. RP Perkins, EJ (reprint author), USA, Engineer Res & Dev Ctr, Vicksburg, MS USA. NR 107 TC 0 Z9 0 U1 0 U2 2 PU ELSEVIER ACADEMIC PRESS INC PI SAN DIEGO PA 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 USA BN 978-0-12-396508-0 PY 2013 BP 113 EP 136 PG 24 WC Mathematical & Computational Biology; Toxicology SC Mathematical & Computational Biology; Toxicology GA BFR29 UT WOS:000321041500008 ER PT J AU Hohenforst-Schmidt, W Zarogoulidis, P Darwiche, K Vogl, T Goldberg, EP Huang, HD Simoff, M Li, Q Browning, R Turner, FJ Le Pivert, P Spyratos, D Zarogoulidis, K Celikoglu, SI Celikoglu, F Brachmann, J AF Hohenforst-Schmidt, Wolfgang Zarogoulidis, Paul Darwiche, Kaid Vogl, Thomas Goldberg, Eugene P. Huang, Haidong Simoff, Michael Li, Qiang Browning, Robert Turner, Francis J. Le Pivert, Patrick Spyratos, Dionysios Zarogoulidis, Konstantinos Celikoglu, Seyhan I. Celikoglu, Firuz Brachmann, Johannes TI Intratumoral chemotherapy for lung cancer: re-challenge current targeted therapies SO DRUG DESIGN DEVELOPMENT AND THERAPY LA English DT Article DE cisplatin; lymph nodes; chemotherapy; intratumoral; lung cancer ID DRUG-DELIVERY; IN-VIVO; ANTITUMOR ACTIVITIES; ELECTROSPUN FIBERS; AIRWAY-OBSTRUCTION; PANCREATIC-CANCER; ANTICANCER DRUGS; SOLID TUMORS; INJECTION; EFFICACY AB Strategies to enhance the already established doublet chemotherapy regimen for lung cancer have been investigated for more than 20 years. Initially, the concept was to administer chemotherapy drugs locally to the tumor site for efficient diffusion through passive transport within the tumor. Recent advances have enhanced the diffusion of pharmaceuticals through active transport by using pharmaceuticals designed to target the genome of tumors. In the present study, five patients with non-small cell lung cancer epidermal growth factor receptor (EGFR) negative stage IIIa-IV International Union Against Cancer 7 (UICC-7), and with Eastern Cooperative Oncology Group (ECOG) 2 scores were administered platinum-based doublet chemotherapy using combined intratumoral-regional and intravenous route of administration. Cisplatin analogues were injected at 0.5%-1% concentration within the tumor lesion and proven malignant lymph nodes according to pretreatment histological/cytological results and the concentration of systemic infusion was decreased to 70% of a standard protocol. This combined intravenous plus intratumoral-regional chemotherapy is used as a first line therapy on this short series of patients. To the best of our knowledge this is the first report of direct treatment of involved lymph nodes with cisplatin by endobronchial ultrasound drug delivery with a needle without any adverse effects. The initial overall survival and local response are suggestive of a better efficacy compared to established doublet cisplatin-based systemic chemotherapy in (higher) standard concentrations alone according to the UICC 7 database expected survival. An extensive search of the literature was performed to gather information of previously published literature of intratumoral chemo-drug administration and formulation for this treatment modality. Our study shows a favorable local response, more than a 50% reduction, for a massive tumor mass after administration of five sessions of intratumoral chemotherapy plus two cycles of low-dose intravenous chemotherapy according to our protocol. These encouraging results (even in very sick ECOG 2 patients with central obstructive non-small cell lung cancer having a worse prognosis and quality of life than a non-small cell lung cancer in ECOG 0 of the same tumor node metastasis [TNM]-stage without central obstruction) for a chemotherapy-only protocol that differs from conventional cisplatin-based doublet chemotherapy by the route, target site, and dose paves the way for broader applications of this technique. Finally, future perspectives of this treatment and pharmaceutical design for intratumoral administration are presented. C1 [Hohenforst-Schmidt, Wolfgang; Brachmann, Johannes] Univ Wurzburg, Coburg Hosp, Med Clin 2, Coburg, Germany. [Zarogoulidis, Paul; Spyratos, Dionysios; Zarogoulidis, Konstantinos] Univ Thessaloniki, Dept Pulm, Oncol Unit, G Papanikolaou Gen Hosp, GR-54006 Thessaloniki, Greece. [Zarogoulidis, Paul; Darwiche, Kaid] Univ Duisburg Essen, Univ Hosp, West German Lung Ctr, Dept Intervent Pneumol,Ruhrlandklin, Essen, Germany. [Vogl, Thomas] Goethe Univ Frankfurt, Dept Diagnost & Intervent Radiol, D-60054 Frankfurt, Germany. [Goldberg, Eugene P.] Univ Florida, Dept Mat Sci & Engn, Gainesville, FL 32611 USA. [Li, Qiang] Second Mil Med Univ, Dept Resp Dis, Changhai Hosp, Affiliated Hosp 1, Shanghai, Peoples R China. [Simoff, Michael] Wayne State Univ, Sch Med, Henry Ford Hosp, Detroit, MI 48202 USA. [Browning, Robert] Walter Reed Army Med Ctr, Natl Naval Med Ctr, Bethesda, MD USA. [Turner, Francis J.] Univ Nevada, Sch Med, Natl Supercomp Ctr Energy & Environm, Las Vegas, NV 89154 USA. [Le Pivert, Patrick] Intervent Drug Delivery Syst & Strategies ID2S2, Jupiter, FL USA. [Celikoglu, Seyhan I.; Celikoglu, Firuz] Istanbul Univ, Cerrahpasa Med Fac, Pulm Dept, Istanbul, Turkey. RP Zarogoulidis, P (reprint author), Univ Thessaloniki, Dept Pulm, Oncol Unit, G Papanikolaou Gen Hosp, GR-54006 Thessaloniki, Greece. EM pzarog@hotmail.com NR 92 TC 16 Z9 17 U1 2 U2 14 PU DOVE MEDICAL PRESS LTD PI ALBANY PA PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND SN 1177-8881 J9 DRUG DES DEV THER JI Drug Des. Dev. Ther. PY 2013 VL 7 BP 571 EP 583 DI 10.2147/DDDT.S46393 PG 13 WC Chemistry, Medicinal; Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA 185DG UT WOS:000321944800001 PM 23898222 ER PT S AU Piekiel, NW Churaman, WA Morris, CJ Currano, LJ AF Piekiel, Nicholas W. Churaman, Wayne A. Morris, Christopher J. Currano, Luke J. GP IEEE TI COMBUSTION AND MATERIAL CHARACTERIZATION OF POROUS SILICON NANOENERGETICS SO 26TH IEEE INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS 2013) SE Proceedings IEEE Micro Electro Mechanical Systems LA English DT Proceedings Paper CT 26th IEEE International Conference on Micro Electro Mechanical Systems (MEMS) CY JAN 20-24, 2013 CL Taipei, TAIWAN SP IEEE, IEEE Robot & Automat Soc (RA), Natl Sci Council, Tsing Hua Univ, Ind Technol Res Inst (ITRI) ID EXPLOSIVE DEVICES; FILMS AB Certain porous silicon (PS) structures have demonstrated energetic characteristics when mixed with an appropriate oxidizer [1-4]. However, limited studies on the effect of PS structure on its combustion have been performed. This work investigates how various material properties of PS films; surface area, porosity and pore size, affect the combustion process. With pore sizes in the range of 2.6-5.2 nm and surface area reaching over 900 m(2)/g, these materials are capable of considerably fast reactions. Combustion characterization is performed through high speed imaging at a rate of 930,000 frames per second. Propagation speeds in the current study range from 300 - 1950 m/s, and some relationships between the pore characteristics and the propagation velocity are observed. C1 [Piekiel, Nicholas W.; Churaman, Wayne A.; Morris, Christopher J.; Currano, Luke J.] USA, Res Lab, Adelphi, MD USA. RP Piekiel, NW (reprint author), USA, Res Lab, Adelphi, MD USA. EM nicholas.piekiel.ctr@mail.mil NR 18 TC 6 Z9 6 U1 0 U2 5 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1084-6999 BN 978-1-4673-5654-1 J9 PROC IEEE MICR ELECT PY 2013 BP 449 EP 452 PG 4 WC Engineering, Electrical & Electronic; Nanoscience & Nanotechnology SC Engineering; Science & Technology - Other Topics GA BFM53 UT WOS:000320549200115 ER PT J AU Campbell, S Balco, G Todd, C Conway, H Huybers, K Simmons, C Vermeulen, M AF Campbell, Seth Balco, Greg Todd, Claire Conway, Howard Huybers, Kathleen Simmons, Christopher Vermeulen, Michael TI Radar-detected englacial stratigraphy in the Pensacola Mountains, Antarctica: implications for recent changes in ice flow and accumulation SO ANNALS OF GLACIOLOGY LA English DT Article ID LAST GLACIAL MAXIMUM; WEST ANTARCTICA; EAST ANTARCTICA; SHEET; STREAM; SHELF; CONSTRAINTS; DYNAMICS; HISTORY AB We used measurements of radar-detected stratigraphy, surface ice-flow velocities and accumulation rates to investigate relationships between local valley-glacier and regional ice-sheet dynamics in and around the Schmidt Hills, Pensacola Mountains, Antarctica. Ground-penetrating radar profiles were collected perpendicular to the long axis of the Schmidt Hills and the margin of Foundation Ice Stream (FIS). Within the valley confines, the glacier consists of blue ice, and profiles show internal stratigraphy dipping steeply toward the nunataks and truncated at the present-day ablation surface. Below the valley confines, the blue ice is overlain by firn. Data show that upward-progressing overlap of actively accumulating firn onto valley-glacier ice is slightly less than ice flow out of the valleys over the past similar to 1200 years. The apparent slightly negative mass balance (-0.25 cm a(-1)) suggests that ice-margin elevations in the Schmidt Hills may have lowered over this time period, even without a change in the surface elevation of FIS. Results suggest that (1) mass-balance gradients between local valley glaciers and regional ice sheets should be considered when using local information to estimate regional ice surface elevation changes; and (2) interpretation of shallow ice structures imaged with radar can provide information about local ice elevation changes and stability. C1 [Campbell, Seth] Univ Maine, Orono, ME 04469 USA. [Campbell, Seth] US Army Cold Reg Res & Engn Lab CRREL, Hanover, NH USA. [Balco, Greg] Berkeley Geochronol Ctr, Berkeley, CA USA. [Todd, Claire; Vermeulen, Michael] Pacific Lutheran Univ, Tacoma, WA 98447 USA. [Conway, Howard; Huybers, Kathleen] Univ Washington, Seattle, WA 98195 USA. [Simmons, Christopher] AMGA, IFMGA, Seattle, WA USA. RP Campbell, S (reprint author), Univ Maine, Orono, ME 04469 USA. EM seth.campbell@umit.maine.edu FU US National Science Foundation [ANT-0838783, ANT-0838784, ANT-0838256]; Polar Geospatial Center FX We thank Richard Hindmarsh, Gwenn Flowers and two anonymous reviewers for carefully reviewing and improving the manuscript with their feedback. We thank Steven Arcone and John Stone for helpful comments during various stages of the project. We thank Nathan Lamie, Steven Decato and Jesse Stanley (US Army CRREL) for providing technical support prior to and following field seasons, and Robert Hawley and Steven Arcone for providing field equipment. We thank the Polar Geospatial Center for support and access to satellite imagery. Funding for this research was provided by the US National Science Foundation to Conway (ANT-0838783), Balco (ANT-0838784) and Todd (ANT-0838256). NR 28 TC 5 Z9 5 U1 1 U2 8 PU INT GLACIOL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE CB2 1ER, ENGLAND SN 0260-3055 J9 ANN GLACIOL JI Ann. Glaciol. PY 2013 VL 54 IS 63 BP 91 EP 100 DI 10.3189/2013AoG63A371 PN 1 PG 10 WC Geography, Physical; Geosciences, Multidisciplinary SC Physical Geography; Geology GA 181RF UT WOS:000321685500012 ER PT J AU Rice, MT Jacobson, RD Caldwell, DR McDermott, SD Paez, FI Aburizaiza, AO Curtin, KM Stefanidis, A Qin, H AF Rice, Matthew T. Jacobson, R. Daniel Caldwell, Douglas R. McDermott, Scott D. Paez, Fabiana I. Aburizaiza, Ahmad O. Curtin, Kevin M. Stefanidis, Anthony Qin, Han TI Crowdsourcing techniques for augmenting traditional accessibility maps with transitory obstacle information SO CARTOGRAPHY AND GEOGRAPHIC INFORMATION SCIENCE LA English DT Article; Proceedings Paper CT International Cartographic Conference (ICC) CY AUG 25-30, 2013 CL Dresden, GERMANY DE crowdsourcing; accessibility; blindness ID GEOGRAPHICAL INFORMATION; MARITIME ENVIRONMENT; SYSTEM; BLIND; REPRESENTATIONS; OPENSTREETMAP; GUIDANCE; WEB AB One of the most scrutinized contemporary techniques for geospatial data collection and production is crowdsourcing. This inverts the traditional top-down geospatial data production and distribution methods by emphasizing on the participation of the end user or community. The technique has been shown to be particularly useful in the domain of accessibility mapping, where it can augment traditional mapping methods and systems by providing information about transitory obstacles in the built environment. This research paper presents details of techniques and applications of crowdsourcing and related methods for improving the presence of transitory obstacles in accessibility mapping systems. The obstacles are very difficult to incorporate with any other traditional mapping workflow, since they typically appear in an unplanned manner and disappear just as quickly. Nevertheless, these obstacles present a major impediment to navigating an unfamiliar environment. Fortunately, these obstacles can be reported, defined, and captured through a variety of crowdsourcing techniques, including gazetteer-based geoparsing and active social media harvesting, and then referenced in a crowdsourced mapping system. These techniques are presented, along with context from research in tactile cartography and geo-enabled accessibility systems. C1 [Rice, Matthew T.; McDermott, Scott D.; Paez, Fabiana I.; Aburizaiza, Ahmad O.; Curtin, Kevin M.; Stefanidis, Anthony; Qin, Han] George Mason Univ, Dept Geog & Geoinformat Sci, Fairfax, VA 22030 USA. [Jacobson, R. Daniel] Univ Calgary, Dept Geog, Calgary, AB T2N 1N4, Canada. [Caldwell, Douglas R.] USA, Engn Res & Dev Ctr, Alexandria, VA 22315 USA. [Stefanidis, Anthony] George Mason Univ, Ctr Geospatial Intelligence, Fairfax, VA 22030 USA. RP Rice, MT (reprint author), George Mason Univ, Dept Geog & Geoinformat Sci, Fairfax, VA 22030 USA. EM rice@gmu.edu OI Jacobson, Dan/0000-0002-9668-4456 NR 58 TC 5 Z9 5 U1 1 U2 18 PU TAYLOR & FRANCIS INC PI PHILADELPHIA PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA SN 1523-0406 J9 CARTOGR GEOGR INF SC JI Cartogr. Geogr. Inf. Sci. PY 2013 VL 40 IS 3 SI SI BP 210 EP 219 DI 10.1080/15230406.2013.799737 PG 10 WC Geography SC Geography GA 178MQ UT WOS:000321452500008 ER PT J AU Trejos, T Koons, R Weis, P Becker, S Berman, T Dalpe, C Duecking, M Buscaglia, J Eckert-Lumsdon, T Ernst, T Hanlon, C Heydon, A Mooney, K Nelson, R Olsson, K Schenk, E Palenik, C Pollock, EC Rudell, D Ryland, S Tarifa, A Valadez, M van Es, A Zdanowicz, V Almirall, J AF Trejos, Tatiana Koons, Robert Weis, Peter Becker, Stefan Berman, Ted Dalpe, Claude Duecking, Marc Buscaglia, JoAnn Eckert-Lumsdon, Tiffany Ernst, Troy Hanlon, Christopher Heydon, Alex Mooney, Kim Nelson, Randall Olsson, Kristine Schenk, Emily Palenik, Christopher Pollock, Edward Chip Rudell, David Ryland, Scott Tarifa, Anamary Valadez, Melissa van Es, Andrew Zdanowicz, Vincent Almirall, Jose TI Forensic analysis of glass by mu-XRF, SN-ICP-MS, LA-ICP-MS and LA-ICP-OES: evaluation of the performance of different criteria for comparing elemental composition SO JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY LA English DT Article ID ATOMIC-EMISSION-SPECTROMETRY; PLASMA-MASS-SPECTROMETRY; X-RAY-FLUORESCENCE; INDUCED BREAKDOWN SPECTROSCOPY; LASER-ABLATION; QUANTITATIVE-ANALYSIS; SAMPLING STRATEGIES; REFRACTIVE-INDEX; MATCH CRITERIA; FRAGMENTS AB Four interlaboratory tests were designed to evaluate the performance of match criteria for forensic comparisons of elemental composition of glass by mu-XRF, solution nebulization SN-ICP-MS, LA-ICP-OES and LA-ICP-MS. A total of 24 analysts in 18 laboratories participated in the tests. Glass specimens were selected to study the capabilities of the techniques to discriminate glass produced in the same manufacturing plant at different time intervals and to associate samples that originated from a single source. The assessment of the effectiveness of several match criteria included: confidence interval (+6s, +5s, +4s, +3s, +2s), modified confidence interval, t-test, range overlap, and Hotelling's T-2. Error rates are reported for each of these criteria. Recommended match criteria were those found to produce the lowest combinations of type 1 and type 2 error rates. Performance of the studied match criteria was dependent on the homogeneity of the glass sources, the repeatability between analytical measurements, and the number of elements that were measured. The best results for mu-XRF data were obtained using spectral overlay followed by a +/-3s confidence interval or range overlap. For ICP-based measurements, a wider match criterion, such as a modified confidence interval based on a fixed minimum relative standard deviation (+/-4s, > 3-5% RSD), is recommended due to the inherent precision of those methods (typically < 1-5% RSD) and the greater number of elements measured. Glass samples that were manufactured in different plants, or at the same plant weeks or months apart, were readily differentiated by elemental composition when analyzed by these sensitive methods. C1 [Trejos, Tatiana; Schenk, Emily; Tarifa, Anamary; Almirall, Jose] Florida Int Univ, Int Forens Res Inst, Miami, FL 33199 USA. [Koons, Robert; Buscaglia, JoAnn] Fed Bur Invest, Lab Div, Counterterrorism & Forens Sci Res Unit, Quantico, VA 22135 USA. [Weis, Peter; Becker, Stefan; Duecking, Marc] Bundeskriminalamt BKA, Forens Sci Inst, D-65173 Wiesbaden, Germany. [Berman, Ted; Ryland, Scott] Orlando Reg Operat Ctr, Florida Dept Law Enforcement, Orlando, FL 32801 USA. [Dalpe, Claude] Royal Canadian Mounted Police Dept, Forens Sci & Identicat Serv, Ottawa, ON, Canada. [Eckert-Lumsdon, Tiffany; Mooney, Kim] US Army, Criminal Invest Lab, Forest Pk, GA 30297 USA. [Ernst, Troy] Michigan State Police Grand Rapids Lab, Grand Rapids, MI 49503 USA. [Hanlon, Christopher] Forens Sci Serv Bur, Miami Dade Police Dept, Miami, FL 33172 USA. [Heydon, Alex; Rudell, David] Ctr Forens Sci, Toronto, ON M7A 268, Canada. [Nelson, Randall] Tennessee Bur Invest, Forens Serv Div, Nashville, TN 37216 USA. [Olsson, Kristine] Johnson Cty Crime Lab, Mission, KS 66202 USA. [Palenik, Christopher] Microtrace LLC, Elgin, IL 60123 USA. [Pollock, Edward Chip] Lab Forens Sci, Sacramento, CA USA. [Valadez, Melissa] Publ Safety Crime Lab, Texas Dept, Austin, TX 78752 USA. [van Es, Andrew] Netherlands Forens Inst, NL-2497 GB The Hague, Netherlands. [Zdanowicz, Vincent] CBP Res Lab, Dept Homeland Secur, Springfield, VA 22153 USA. RP Almirall, J (reprint author), Florida Int Univ, Int Forens Res Inst, 11200 SW 8th St, Miami, FL 33199 USA. EM almirall@fiu.edu RI Almirall, Jose/D-1280-2010 OI Almirall, Jose/0000-0002-5257-7499 FU National Institute of Justice, Office of Justice Programs, U.S. Department of Justice [2010-DN-BX-K179] FX This project was supported by Award no. 2010-DN-BX-K179 from the National Institute of Justice, Office of Justice Programs, U.S. Department of Justice. The opinions, findings, and conclusions or recommendations expressed in this presentation are those of the authors and do not necessarily reflect those of the Department of Justice, the Department of the Army or the Department of Defense. This is publication number 12-15 of the FBI Laboratory Division. Names of commercial manufacturers are provided for identification purposes only, and inclusion does not imply endorsement of the manufacturer, or its products or services by the FBI. The views expressed are those of the authors and do not necessarily reflect the official policy or position of the FBI or the U. S. Government. Thanks to all of the Elemental Analysis Working Group members and their agencies for devoting the time necessary to complete this project. NR 40 TC 8 Z9 9 U1 7 U2 41 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 0267-9477 EI 1364-5544 J9 J ANAL ATOM SPECTROM JI J. Anal. At. Spectrom. PY 2013 VL 28 IS 8 BP 1270 EP 1282 DI 10.1039/c3ja50128k PG 13 WC Chemistry, Analytical; Spectroscopy SC Chemistry; Spectroscopy GA 181NO UT WOS:000321674600011 ER PT S AU Prokopenko, OV Krivorotov, IN Meitzler, TJ Bankowski, E Tiberkevich, VS Slavin, AN AF Prokopenko, Oleksandr V. Krivorotov, Ilya N. Meitzler, Thomas J. Bankowski, Elena Tiberkevich, Vasil S. Slavin, Andrei N. BE Demokritov, SO Slavin, AN TI Spin-Torque Microwave Detectors SO MAGNONICS: FROM FUNDAMENTALS TO APPLICATIONS SE Topics in Applied Physics LA English DT Review; Book Chapter ID MAGNETIC TUNNEL-JUNCTIONS; PHASE-LOCKING; DRIVEN; WAVES; EXCITATIONS AB It is known that the spin-transfer torque (STT) effect provides a new method of manipulation of magnetization in nano-scale devices. According to the STT effect, bias DC current traversing magnetic multilayers can transfer angular magnetic moments from one layer to another, which can give rise to microwave dynamics of magnetization in the layer. However, it is clear that an inverse effect is also possible. This inverse effect leads to the so-called spin-torque diode effect, first originally observed experimentally in 2005. The spin-torque diode effect is a rectification effect of the input microwave current in a magnetoresistive junction. In this case, the resonance oscillations of the junction resistance can mix with the oscillations of the input microwave current and produce a large enough output DC voltage across the junction. The devices which utilize this effect are called the spin-torque microwave detectors (STMD). In this chapter, we review the general properties of STMDs and consider the performance of a STMD in two different dynamic regimes of detector operation: in the well-known traditional in-plane regime of STMD operation and in the recently discovered novel out-of-plane regime of STMD operation. We analyze the performance of a STMD and consider the typical applications for such detectors in both regimes. C1 [Prokopenko, Oleksandr V.] Taras Shevchenko Natl Univ Kyiv, Fac Radiophys, UA-01601 Kiev, Ukraine. [Krivorotov, Ilya N.] Univ Calif Irvine, Dept Phys & Astron, Irvine, CA 92697 USA. [Meitzler, Thomas J.; Bankowski, Elena] US Army TARDEC, Warren, MI 48397 USA. [Tiberkevich, Vasil S.; Slavin, Andrei N.] Oakland Univ, Dept Phys, Rochester, MI 48309 USA. RP Slavin, AN (reprint author), Oakland Univ, Dept Phys, Rochester, MI 48309 USA. EM ovp@univ.kiev.ua; ikrivoro@uci.edu; thomas.j.meitzler.civ@mail.mil; elena.n.bankowski.civ@mail.mil; tyberkev@oakland.edu; slavin@oakland.edu RI Tiberkevich, Vasil/A-8697-2008; Meitzler, Thomas/D-1065-2017 OI Tiberkevich, Vasil/0000-0002-8374-2565; NR 22 TC 10 Z9 10 U1 4 U2 28 PU SPRINGER-VERLAG BERLIN PI BERLIN PA HEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY SN 0303-4216 BN 978-3-642-30246-6 J9 TOP APPL PHYS JI Top. Appl. Phys. PY 2013 VL 125 BP 143 EP 161 DI 10.1007/978-3-642-30247-3_11 D2 10.1007/978-3-642-30247-3 PG 19 WC Materials Science, Multidisciplinary; Physics, Applied SC Materials Science; Physics GA BFW94 UT WOS:000321718800012 ER PT S AU Cole, DM Hopkins, MA Ketcham, SA AF Cole, David M. Hopkins, Mark A. Ketcham, Stephen A. BE Yu, A Dong, K Yang, R Luding, S TI Dynamic and Impact Contact Mechanics of Geologic Materials: Grain-scale Experiments and Modeling SO POWDERS AND GRAINS 2013 SE AIP Conference Proceedings LA English DT Proceedings Paper CT 7th International Conference on Micromechanics of Granular Media (Powders and Grains) CY JUL 08-12, 2013 CL Sydney, AUSTRALIA SP Assoc Study Micromechan Granular Media (AEMMG), Univ New S Wales (UNSW), Lab Simulat & Modelling Particulate Syst (SIMPAS), Curtin Univ (CU), Dept Chemical Engn, Univ Twente (UT), Multi Scale Mech Grp (CTW & MESA+), JMBC Res Sch Fluid Mechan, Elsevier, Univ New S Wales (UNSW), Sch Mat Sci & Engn DE Contact mechanics; geologic materials; experiments; discrete element modeling AB High fidelity treatments of the generation and propagation of seismic waves in naturally occurring granular materials is becoming more practical given recent advancements in our ability to model complex particle shapes and their mechanical interaction. Of particular interest are the grain-scale processes that are activated by impact events and the characteristics of force transmission through grain contacts. To address this issue, we have developed a physics based approach that involves laboratory experiments to quantify the dynamic contact and impact behavior of granular materials and incorporation of the observed behavior indiscrete element models. The dynamic experiments do not involve particle damage and emphasis is placed on measured values of contact stiffness and frictional loss. The normal stiffness observed in dynamic contact experiments at low frequencies (e.g., 10 Hz) are shown to be in good agreement with quasistatic experiments on quartz sand. The results of impact experiments - which involve moderate to extensive levels of particle damage - are presented for several types of naturally occurring granular materials (several quartz sands, magnesite and calcium carbonate ooids). Implementation of the experimental findings in discrete element models is discussed and the results of impact simulations involving up to 5 x 10(5) grains are presented. C1 [Cole, David M.; Hopkins, Mark A.; Ketcham, Stephen A.] USA, Cold Reg Res & Engn Lab, Engineer Res & Dev Ctr, Hanover, NH 03755 USA. RP Cole, DM (reprint author), USA, Cold Reg Res & Engn Lab, Engineer Res & Dev Ctr, 72 Lyme Rd, Hanover, NH 03755 USA. NR 4 TC 1 Z9 1 U1 0 U2 2 PU AMER INST PHYSICS PI MELVILLE PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA SN 0094-243X BN 978-0-7354-1166-1 J9 AIP CONF PROC PY 2013 VL 1542 BP 221 EP 224 DI 10.1063/1.4811907 PG 4 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied SC Science & Technology - Other Topics; Materials Science; Physics GA BFQ84 UT WOS:000321003200050 ER PT S AU Ayers, J Owens, CT Liu, KC Swenson, E Ghoshal, A Weiss, V AF Ayers, J. Owens, C. T. Liu, K. C. Swenson, E. Ghoshal, A. Weiss, V. BE Thompson, DO Chimenti, DE TI GUIDED WAVE-BASED J-INTEGRAL ESTIMATION FOR DYNAMIC STRESS INTENSITY FACTORS USING 3D SCANNING LASER DOPPLER VIBROMETRY SO REVIEW OF PROGRESS IN QUANTITATIVE NONDESTRUCTIVE EVALUATION, VOLS 32A AND 32B SE AIP Conference Proceedings LA English DT Proceedings Paper CT 39th Annual Review of Progress in Quantitative Nondestructive Evaluation (QNDE) CY JUL 15-20, 2012 CL Denver, CO SP QNDE Programs, AF Res Lab, Army Res Lab, Amer Soc Nondestruct Testing (ASNT), Dept Energy, AMES Lab, Fed Aviat Adm (FAA), Natl Aeronaut & Space Adm (NASA), Natl Sci Fdn (NSF), Ind/Univ Cooperat Res Ctr, Iowa State Univ, Ctr Nondestruct Evaluat DE Guided Waves; Stress Intensity Factors; Dynamic Excitation; Laser Vibrometry ID BOUNDARY-ELEMENT METHOD; GRADED MATERIALS; CRACKS; COMPUTATION; FRACTURE AB The application of guided waves to interrogate remote areas of structural components has been researched extensively in characterizing damage. However, there exists a sparsity of work in using piezoelectric transducer-generated guided waves as a method of assessing stress intensity factors (SIF). This quantitative information enables accurate estimation of the remaining life of metallic structures exhibiting cracks, such as military and commercial transport vehicles. The proposed full wavefield approach, based on 3D laser vibrometry and piezoelectric transducer-generated guided waves, provides a practical means for estimation of dynamic stress intensity factors (DSIF) through local strain energy mapping via the J-integral. Strain energies and traction vectors can be conveniently estimated from wavefield data recorded using 3D laser vibrometry, through interpolation and subsequent spatial differentiation of the response field. Upon estimation of the J-integral, it is possible to obtain the corresponding DSIF terms. For this study, the experimental test matrix consists of aluminum plates with manufactured defects representing canonical elliptical crack geometries under uniaxial tension that are excited by surface mounted piezoelectric actuators. The defects' major to minor axes ratios vary from unity to approximately 133. Finite element simulations are compared to experimental results and the relative magnitudes of the J-integrals are examined. C1 [Ayers, J.; Ghoshal, A.; Weiss, V.] USA, Vehicle Technol Directorate, Res Lab, Aberdeen, MD 21005 USA. RP Ayers, J (reprint author), USA, Vehicle Technol Directorate, Res Lab, Aberdeen, MD 21005 USA. EM james.t.ayers.civ@mail.mil; christopher.owens@us.af.mil NR 14 TC 0 Z9 0 U1 0 U2 4 PU AMER INST PHYSICS PI MELVILLE PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA SN 0094-243X BN 978-0-7354-1129-6 J9 AIP CONF PROC PY 2013 VL 1511 BP 51 EP 58 DI 10.1063/1.4789030 PG 8 WC Materials Science, Characterization & Testing SC Materials Science GA BFM02 UT WOS:000320452600004 ER PT S AU Saldanha, N Malocha, DC Youngquist, RC AF Saldanha, N. Malocha, D. C. Youngquist, R. C. GP IEEE TI Coherence Multiplexed Passive Wireless SAW RFID Tag System SO 2013 IEEE TOPICAL CONFERENCE ON WIRELESS SENSORS AND SENSOR NETWORKS (WISNET) SE IEEE Topical Conference on Wireless Sensors and Sensor Networks LA English DT Proceedings Paper CT IEEE Topical Conference on Wireless Sensors and Sensor Networks (WiSNet) CY JAN 20-23, 2013 CL Austin, TX SP IEEE, IEEE Microwave Theory & Tech Soc (MTT-S), IEEE Commun Soc (ComSoc), IEEE Antennas & Propagat Soc (APS), IEEE Engn Med & Biol Soc (EMBS) DE SAW RFID system; coherence multiplexing; SAW multiplexing; passive wireless RFID ID SENSORS AB This paper discusses a novel coherence multiplexed system for passive surface acoustic wave (SAW) RF-identification (RFID) tags. The method is adapted from optical coherence-domain reflectometry (OCDR) which is widely used today in optical coherence tomography (OCT) for medical applications. The paper discusses the coherence multiplexing technique as applied to SAW RFID. A broadband white Gaussian noise source is used as the interrogation signal and one of the major advantages is the large signal dynamic range obtained. A prototype transceiver system was built at 915MHz and used for wireless interrogation of SAW tags. The signal processing technique is discussed and the results of wireless multiplexing of four RFID SAW tags are shown. C1 [Saldanha, N.; Malocha, D. C.] Univ Cent Florida, Elect & Comp Engn Dept, Orlando, FL 32816 USA. [Youngquist, R. C.] NASA, Kennedy Space Ctr, FL 32899 USA. [Saldanha, N.] US Army, Commun Elect Res, Dev & Engn Ctr, Aberdeen Proving Ground, MD 21005 USA. RP Saldanha, N (reprint author), Univ Cent Florida, Elect & Comp Engn Dept, Orlando, FL 32816 USA. NR 11 TC 5 Z9 5 U1 0 U2 3 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2330-7900 BN 978-1-4673-3105-0; 978-1-4673-3104-3 J9 IEEE TOPIC CONF WIRE PY 2013 BP 4 EP 6 PG 3 WC Engineering, Electrical & Electronic SC Engineering GA BFP46 UT WOS:000320869800002 ER PT J AU Arnold, JR Yu, JZ AF Arnold, Jeffrey R. Yu, Jian Zhen TI Foreword. Forty years of conversations in tropospheric chemistry and public health: the legacies of Harvey E. Jeffries and Richard M. Kamens at the University of North Carolina at Chapel Hill SO ENVIRONMENTAL CHEMISTRY LA English DT Editorial Material C1 [Arnold, Jeffrey R.] USA, Corps Engineers, Inst Water Resources, Seattle, WA 98105 USA. [Arnold, Jeffrey R.] Univ Washington, Coll Environm, Joint Inst Study Atmosphere & Ocean, Seattle, WA 98105 USA. [Yu, Jian Zhen] Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China. [Yu, Jian Zhen] Hong Kong Univ Sci & Technol, Div Environm, Kowloon, Hong Kong, Peoples R China. RP Arnold, JR (reprint author), USA, Corps Engineers, Inst Water Resources, 3737 Brooklyn Ave NE,JM Wallace Hall, Seattle, WA 98105 USA. EM jeffrey.r.arnold@usace.army.mil; jian.yu@ust.hk RI Yu, Jian/A-9669-2008 OI Yu, Jian/0000-0002-6165-6500 NR 11 TC 0 Z9 0 U1 0 U2 6 PU CSIRO PUBLISHING PI COLLINGWOOD PA 150 OXFORD ST, PO BOX 1139, COLLINGWOOD, VICTORIA 3066, AUSTRALIA SN 1448-2517 J9 ENVIRON CHEM JI Environ. Chem. PY 2013 VL 10 IS 3 SI SI BP I EP IV DI 10.1071/ENv10n3_FO PG 4 WC Chemistry, Analytical; Environmental Sciences SC Chemistry; Environmental Sciences & Ecology GA 173FU UT WOS:000321064400001 ER PT J AU DiStefano, RJ Black, TR Herleth-King, SS Kanno, Y Mattingly, HT AF DiStefano, Robert J. Black, Tyler R. Herleth-King, Shawna S. Kanno, Yoichiro Mattingly, Hayden T. TI LIFE HISTORIES OF TWO POPULATIONS OF THE IMPERILED CRAYFISH ORCONECTES (PROCERICAMBARUS) WILLIAMSI (DECAPODA: CAMBARIDAE) IN SOUTHWESTERN MISSOURI, USA SO JOURNAL OF CRUSTACEAN BIOLOGY LA English DT Article DE crayfish; life history; Orconectes williamsi ID NEGLECTUS-CHAENODACTYLUS WILLIAMS; FRESH-WATER CRAYFISH; RIVER DRAINAGE; PROPINQUUS GIRARD; IMPLANT ELASTOMER; CANADA DECAPODA; ONTARIO; GROWTH; ASTACIDEA; DYNAMICS AB The imperiled Williams' Crayfish, Orconectes williamsi Fitzpatrick, 1966 is endemic to southwestern Missouri and northwestern Arkansas, U.S.A., an area experiencing rapid urbanization and other land use changes. Populations of O. williamsi in two small streams were studied for 26 months to describe annual reproductive cycles, and gather information about fecundity, sex ratio, size at maturity, size-class structure, and growth. We captured a monthly average of more than 120 O. williamsi from each of the two study populations. The life history of O. williamsi appeared generally similar to what has been reported for several other stream-dwelling species of Orconectes. Breeding season occurred in mid to late autumn and perhaps into early winter. Egg brooding occurred during late winter and early spring, although it was difficult to locate females carrying eggs or hatchlings. Young of year first appeared in samples during May and June. We estimated that these populations of O. williamsi contained 3 or 4 size-classes; smaller O. williamsi grew faster than larger individuals and the mean specific growth rate was about 2% per day during summer. Life history information presented herein will be important if expected future conservation efforts are required. C1 [DiStefano, Robert J.] Missouri Dept Conservat, Columbia, MO 65201 USA. [Black, Tyler R.] North Carolina Wildlife Resources Commiss, Creedmoor, NC 27522 USA. [Herleth-King, Shawna S.] USA, Corps Engineers Chicago Dist, Chicago, IL 60606 USA. [Kanno, Yoichiro; Mattingly, Hayden T.] Tennessee Technol Univ, Dept Biol, Cookeville, TN 38505 USA. RP DiStefano, RJ (reprint author), Missouri Dept Conservat, 3500 East Gans Rd, Columbia, MO 65201 USA. EM Bob.DiStefano@mdc.mo.gov FU Missouri Department of Conservation and Tennessee Technological University FX Missouri Department of Conservation and Tennessee Technological University provided funding. Thanks to T. Boersig, L. Cole, M. Culler, I. Dasho, P. Homer, E. Imhoff, V. Jones, A. Meyer, E. Rahm, J. Rice, C. Riggert, J. Schisler, K. Walker, and J. Westhoff for assistance with data collection, data entry and data management. E. Imhoff constructed the map. Taxonomic verifications were provided by C. A. Taylor (Illinois Natural History Survey). Manuscript reviews were provided by two anonymous reviewers. NR 67 TC 3 Z9 3 U1 0 U2 17 PU CRUSTACEAN SOC PI SAN ANTONIO PA 840 EAST MULBERRY, SAN ANTONIO, TX 78212 USA SN 0278-0372 J9 J CRUSTACEAN BIOL JI J. Crustac. Biol. PD JAN PY 2013 VL 33 IS 1 BP 15 EP 24 DI 10.1163/1937240X-00002109 PG 10 WC Marine & Freshwater Biology SC Marine & Freshwater Biology GA 168BO UT WOS:000320680900003 ER PT J AU Dubick, MA Shek, P Wade, CE AF Dubick, Michael A. Shek, Pang Wade, Charles E. TI ROC trials update on prehospital hypertonic saline resuscitation in the aftermath of the US-Canadian trials SO CLINICS LA English DT Review DE HSD; Hemorrhagic Shock; Inflammation; Volume Expander; Small Volume ID TRAUMATIC BRAIN-INJURY; 7.5-PERCENT SODIUM-CHLORIDE; RANDOMIZED CONTROLLED-TRIAL; SEVERE HEMORRHAGIC-SHOCK; UNCONTROLLED HEMORRHAGE; 6-PERCENT DEXTRAN-70; FLUID RESUSCITATION; BURN RESUSCITATION; MULTICENTER TRIAL; HYPOVOLEMIC SHOCK AB The objectives of this review are to assess the current state of hypertonic saline as a prehospital resuscitation fluid in hypotensive trauma patients, particularly after the 3 major Resuscitation Outcomes Consortium trauma trials in the US and Canada were halted due to futility. Hemorrhage and traumatic brain injury are the leading causes of death in both military and civilian populations. Prehospital fluid resuscitation remains controversial in civilian trauma, but small-volume resuscitation with hypertonic fluids is of utility in military scenarios with prolonged or delayed evacuation times. A large body of pre-clinical and clinical literature has accumulated over the past 30 years on the hemodynamic and, most recently, the anti-inflammatory properties of hypertonic saline, alone or with dextran-70. This review assesses the current state of hypertonic fluid resuscitation in the aftermath of the failed Resuscitation Outcomes Consortium trials. C1 [Dubick, Michael A.] USA, Inst Surg Res, San Antonio, TX USA. [Wade, Charles E.] Univ Texas Hlth Sci Ctr Houston, Houston, TX 77030 USA. RP Dubick, MA (reprint author), USA, Inst Surg Res, San Antonio, TX USA. EM michael.dubick@us.army.mil FU US Army Medical Research Materiel Command; Defense Medical Research and Development Program FX The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense. Funded in part by the US Army Medical Research Materiel Command and by a Defense Medical Research and Development Program grant. NR 54 TC 9 Z9 10 U1 0 U2 3 PU HOSPITAL CLINICAS, UNIV SAO PAULO PI SAO PAULO PA FAC MEDICINA, UNIV SAO PAULO, SAO PAULO, SP 00000, BRAZIL SN 1807-5932 J9 CLINICS JI Clinics PY 2013 VL 68 IS 6 BP 883 EP 886 DI 10.6061/clinics/2013(06)25 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA 165DS UT WOS:000320463800025 PM 23778489 ER PT S AU Chen, JYC Quinn, S Wright, J Barnes, M Barber, D Adams, D AF Chen, Jessie Y. C. Quinn, Stephanie Wright, Julia Barnes, Michael Barber, Daniel Adams, David BE Kuzuoka, H Evers, V Imai, M Forlizzi, J TI Human-Agent Teaming for Robot Management in Multitasking Environments SO PROCEEDINGS OF THE 8TH ACM/IEEE INTERNATIONAL CONFERENCE ON HUMAN-ROBOT INTERACTION (HRI 2013) SE ACMIEEE International Conference on Human-Robot Interaction LA English DT Proceedings Paper CT 8th Annual ACM/IEEE International Conference on Human-Robot Interaction (HRI) CY MAR 03-06, 2013 CL Tokyo, JAPAN SP ACM, IEEE, IEEE Robot & Automat (RA), AAAI, Human Factors & Ergonom Soc (HFES), ACM SIGCHI, ACM SIGART DE Human Robot Interaction; Simulation; Military; Individual Differences; Multitasking ID SUPERVISORY CONTROL; MULTIPLE ROBOTS AB In the current experiment, we simulated a multitasking environment and evaluated of an intelligent agent, RoboLeader, on the performance of human operators who had the responsibility of managing the plans/routes for three vehicles (their owned manned ground vehicle, an aerial robotic vehicle, and a ground robotic vehicle), while maintaining proper awareness of their immediate environment (i.e threat detection). Results showed that RoboLeader's level of autonomy had a significant impact of participants concurrent target detection task. Participants detected more targets in the Semi-Auto and Full-Auto conditions than in the Manual condition. Participants reported significantly higher workload in the Manual condition than in the two RoboLeader conditions (Semi-Auto and Full-Auto). Operator spatial ability also had a significant impact on target detection and situation awareness performance measures. C1 [Chen, Jessie Y. C.; Quinn, Stephanie; Wright, Julia; Barnes, Michael] US Army Res Lab, Human Res & Engn Directorate, Adelphi, MD 20783 USA. [Barber, Daniel; Adams, David] Univ Cent Florida, Inst Simulat & Training, Orlando, FL 32816 USA. RP Chen, JYC (reprint author), US Army Res Lab, Human Res & Engn Directorate, Adelphi, MD 20783 USA. NR 9 TC 2 Z9 2 U1 0 U2 8 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2167-2121 BN 978-1-4673-3055-8; 978-1-4673-3099-2 J9 ACMIEEE INT CONF HUM PY 2013 BP 103 EP + PG 2 WC Engineering, Electrical & Electronic; Robotics SC Engineering; Robotics GA BFN86 UT WOS:000320655500028 ER PT S AU Carroll, JJ Litz, MS Netherton, KA Henriquez, SL Pereira, NR Burns, DA Karamian, SA AF Carroll, J. J. Litz, M. S. Netherton, K. A. Henriquez, S. L. Pereira, N. R. Burns, D. A. Karamian, S. A. BE McDaniel, FD Doyle, BL Glass, GA Wang, Y TI Nuclear Structure And Depletion Of Nuclear Isomers Using Electron Linacs SO APPLICATION OF ACCELERATORS IN RESEARCH AND INDUSTRY SE AIP Conference Proceedings LA English DT Proceedings Paper CT 22nd International Conference on the Application of Accelerators in Research and Industry (CAARI) CY AUG 05-10, 2012 CL Fort Worth, TX SP Sandia Natl Labs, Univ N Texas, Los Alamos Natl Lab, Pacific NW Natl Lab, High Voltage Engn Europa B V, Kurt J Lester Co, Natl Electrostat Corp DE Nuclear isomer; isomer depletion; nuclear structure; bremsstrahlung; electron linac ID COULOMB-EXCITATION; EMISSION AB Long-lived nuclear excited states (isomers) have proven important to understanding nuclear structure. With some isomers having half-lives of decades or longer, and intrinsic energy densities reaching 10(12) J/kg, they have also been suggested for a wide range of applications. The ability to effectively transfer a population of nuclei from an isomer to shorter-lived levels will determine the feasibility of any applications. Here is described a first demonstration of the induced depletion of a population of the 438 year isomer of Ag-108 to its 2.38 min ground state, using 6 MeV bremsstrahlung from a modified medical electron linac. The experiment suggests refinements to be implemented in the future and how a similar approach might be applied to study induced depletion of the 1200 year isomer of Ho-166. C1 [Carroll, J. J.; Litz, M. S.; Netherton, K. A.; Henriquez, S. L.; Burns, D. A.] USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. RP Carroll, JJ (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. FU DTRA [HDTRA1-08-1-0014]; Youngstown State University; University of Surrey FX An author (J. C.) wishes to acknowledge early development of these experiments, with support by DTRA under contract HDTRA1-08-1-0014, by G. Trees, B. Detwiler and I. Mills at Youngstown State University, and useful discussions with Phil Walker, University of Surrey. Thanks to Joe Schumer, Naval Research Laboratory, for arranging the availability of the isomer sample. NR 31 TC 2 Z9 2 U1 0 U2 2 PU AMER INST PHYSICS PI MELVILLE PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA SN 0094-243X BN 978-0-7354-1148-7 J9 AIP CONF PROC PY 2013 VL 1525 BP 586 EP 594 DI 10.1063/1.4802396 PG 9 WC Physics, Applied; Physics, Nuclear; Physics, Particles & Fields SC Physics GA BFI58 UT WOS:000319997900117 ER PT J AU Collinger, JL Boninger, ML Bruns, TM Curley, K Wang, W Weber, DJ AF Collinger, Jennifer L. Boninger, Michael L. Bruns, Tim M. Curley, Kenneth Wang, Wei Weber, Douglas J. TI Functional priorities, assistive technology, and brain-computer interfaces after spinal cord injury SO JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT LA English DT Article DE assistive technology; brain-computer interface; disability; function; functional electrical stimulation; neuroprosthetics; priorities; quality of life; spinal cord injury; veterans ID QUALITY-OF-LIFE; NEUROPROSTHETIC DEVICES; CORTICAL CONTROL; PATIENT; GRASP; TETRAPLEGIA; PEOPLE; REHABILITATION; PARTICIPATION; RESTORATION AB Spinal cord injury (SCI) often affects a person's ability to perform critical activities of daily living and can negatively affect his or her quality of life. Assistive technology aims to bridge this gap in order to augment function and increase independence. It is critical to involve consumers in the design and evaluation process as new technologies such as brain-computer interfaces (BCIs) are developed. In a survey study of 57 veterans with SCI participating in the 2010 National Veterans Wheelchair Games, we found that restoration of bladder and bowel control, walking, and arm and hand function (tetraplegia only) were all high priorities for improving quality of life. Many of the participants had not used or heard of some currently available technologies designed to improve function or the ability to interact with their environment. The majority of participants in this study were interested in using a BCI, particularly for controlling functional electrical stimulation to restore lost function. Independent operation was considered to be the most important design criteria. Interestingly, many participants reported that they would consider surgery to implant a BCI even though non-invasiveness was a high-priority design requirement. This survey demonstrates the interest of individuals with SCI in receiving and contributing to the design of BCIs. C1 [Collinger, Jennifer L.; Boninger, Michael L.; Weber, Douglas J.] Dept Vet Affairs Pittsburgh Healthcare Syst, Human Engn Res Labs, Pittsburgh, PA USA. [Collinger, Jennifer L.; Boninger, Michael L.; Bruns, Tim M.; Wang, Wei; Weber, Douglas J.] Univ Pittsburgh, Dept Phys Med & Rehabil, Pittsburgh, PA USA. [Collinger, Jennifer L.; Boninger, Michael L.; Wang, Wei; Weber, Douglas J.] Univ Pittsburgh, Dept Bioengn, Pittsburgh, PA USA. [Boninger, Michael L.; Weber, Douglas J.] Univ Pittsburgh, Dept Rehabil Sci & Technol, Pittsburgh, PA USA. [Curley, Kenneth] USA, Med Res & Mat Command, Ft Detrick, MD USA. RP Collinger, JL (reprint author), VA Pittsburgh Healthcare Syst, Human Engn Res Labs, 6425 Penn Ave,Suite 400, Pittsburgh, PA 15206 USA. EM collingr@pitt.edu OI Bruns, Tim/0000-0003-1692-0541; Boninger, Michael/0000-0001-6966-919X FU VA Office of Research and Development, Rehabilitation Research and Development Service [B6789C]; Paralyzed Veterans of America FX This material was based on work supported by the VA Office of Research and Development, Rehabilitation Research and Development Service (grant B6789C), and the Paralyzed Veterans of America. NR 58 TC 31 Z9 31 U1 5 U2 25 PU JOURNAL REHAB RES & DEV PI BALTIMORE PA DEPT OF VETERANS AFFAIRS REHABIL RES & DEVELOP CTR 103 SOUTH GAY STREET, BALTIMORE, MD 21202-4051 USA SN 0748-7711 J9 J REHABIL RES DEV JI J. Rehabil. Res. Dev. PY 2013 VL 50 IS 2 BP 145 EP 159 DI 10.1682/JRRD.2011.11.0213 PG 15 WC Rehabilitation SC Rehabilitation GA 149FF UT WOS:000319303700004 PM 23760996 ER PT S AU Nataraj, L Jackson, A Giri, L Hubbard, C Bundy, M AF Nataraj, Latha Jackson, Aaron Giri, Lily Hubbard, Clifford Bundy, Mark GP IEEE TI Doped Group-IV Semiconductor Nanocrystals SO PROCEEDINGS OF THE 2013 IEEE 5TH INTERNATIONAL NANOELECTRONICS CONFERENCE (INEC) SE International Nanoelectronics Conference LA English DT Proceedings Paper CT IEEE 5th International Nanoelectronics Conference (INEC) CY JAN 02-04, 2013 CL Singapore, SINGAPORE SP IEEE, IEEE Nanotech Chapter, IEEE Singapore Sect, Nanyang Technol Univ, IEEE Electron Device Soc (EDS), BRUKER, Cascade Microtech, SHIMADZU, ZEISS, Off Naval Res Sci & Technol ID SILICON AB Doped semiconductor nanocrystals offer great potential for microelectronics and integrated optoelectronics. Nanocrystal based technology is promising for several fields of technology such as thin conducting films, light emitting devices, tunable lasers, transistors, photovoltaics, and less harmful alternatives to toxic fluorescent dyes for application in bio-imaging, to name a few, While properties of nanocrystals are tunable through their size, considerable research is underway to explore the influence of dopants on the properties of semiconductor nanocrystals. The introduction of dopants has been elusive for these confined structures due to their nanoscale sizes as well as the possibility of making them degenerate even with the addition of very small quantities of the dopant. Here, we present a facile, low-cost procedure that we have developed for the synthesis of non-degenerate doped semiconductor nanocrystals and study their properties. C1 [Nataraj, Latha; Jackson, Aaron; Giri, Lily; Hubbard, Clifford; Bundy, Mark] USA, Res Lab, Aberdeen Proving Ground, MD USA. RP Nataraj, L (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD USA. EM latha.nataraj.ctr@mail.mil NR 16 TC 0 Z9 0 U1 0 U2 3 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2159-3523 BN 978-1-4673-4841-6 J9 INT NANOELECTR CONF PY 2013 BP 298 EP 299 PG 2 WC Engineering, Electrical & Electronic; Nanoscience & Nanotechnology SC Engineering; Science & Technology - Other Topics GA BFE41 UT WOS:000319409400093 ER PT J AU Berkley, CJ Corner, B Slice, DE AF Berkley, Cameron J. Corner, Brian Slice, Dennis E. TI Craniofacial variation I: Within-population Procrustes analysis in a sample of Armed Services personnel. SO AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY LA English DT Meeting Abstract CT 82nd Annual Meeting of the American-Association-of-Physical-Anthropologists CY APR 09-13, 2013 CL Knoxville, TN SP Amer Assoc Phys Anthropologists C1 [Berkley, Cameron J.; Slice, Dennis E.] Florida State Univ, Dept Comp Sci, Tallahassee, FL 32306 USA. [Corner, Brian] USA, Natick Soldier Res Dev & Engn Ctr, Washington, DC USA. NR 0 TC 0 Z9 0 U1 0 U2 1 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0002-9483 J9 AM J PHYS ANTHROPOL JI Am. J. Phys. Anthropol. PY 2013 VL 150 SU 56 SI SI BP 78 EP 78 PG 1 WC Anthropology; Evolutionary Biology SC Anthropology; Evolutionary Biology GA 132BR UT WOS:000318043201062 ER PT J AU Corner, B Reed, M Hudson, J Zehner, G AF Corner, Brian Reed, Matt Hudson, Jeff Zehner, Greg TI Use of geometric data in human factors and ergonomic applications. SO AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY LA English DT Meeting Abstract CT 82nd Annual Meeting of the American-Association-of-Physical-Anthropologists CY APR 09-13, 2013 CL Knoxville, TN SP Amer Assoc Phys Anthropologists C1 [Corner, Brian] USA, Natick Soldier RDEC, Washington, DC USA. [Reed, Matt] Univ Michigan, Transportat Res Inst, Ann Arbor, MI 48109 USA. [Zehner, Greg] USAF, Res Lab, Wright Patterson AFB, OH USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0002-9483 J9 AM J PHYS ANTHROPOL JI Am. J. Phys. Anthropol. PY 2013 VL 150 SU 56 SI SI BP 103 EP 103 PG 1 WC Anthropology; Evolutionary Biology SC Anthropology; Evolutionary Biology GA 132BR UT WOS:000318043201169 ER PT J AU Pomidor, BJ Corner, B Slice, DE AF Pomidor, Benjamin J. Corner, Brian Slice, Dennis E. TI Craniofacial variation III: Efficient, landmark-free superimposition of head surface scans. SO AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY LA English DT Meeting Abstract CT 82nd Annual Meeting of the American-Association-of-Physical-Anthropologists CY APR 09-13, 2013 CL Knoxville, TN SP Amer Assoc Phys Anthropologists C1 [Pomidor, Benjamin J.; Slice, Dennis E.] Florida State Univ, Dept Comp Sci, Tallahassee, FL 32306 USA. [Corner, Brian] USA, Natick Soldier Res Dev & Engn Ctr, Washington, DC USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0002-9483 J9 AM J PHYS ANTHROPOL JI Am. J. Phys. Anthropol. PY 2013 VL 150 SU 56 SI SI BP 222 EP 223 PG 2 WC Anthropology; Evolutionary Biology SC Anthropology; Evolutionary Biology GA 132BR UT WOS:000318043202177 ER PT J AU Soda, KJ Corner, BD Slice, DE AF Soda, K. James. Corner, Brian D. Slice, Dennis E. TI Craniofacial variation II: Head shape prediction from anthropometric measurement and ancestry. SO AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY LA English DT Meeting Abstract CT 82nd Annual Meeting of the American-Association-of-Physical-Anthropologists CY APR 09-13, 2013 CL Knoxville, TN SP Amer Assoc Phys Anthropologists C1 [Soda, K. James.; Slice, Dennis E.] Florida State Univ, Dept Comp Sci, Tallahassee, FL 32306 USA. [Corner, Brian D.] USA, Natick Soldier Res Dev & Engn Ctr, Washington, DC USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0002-9483 J9 AM J PHYS ANTHROPOL JI Am. J. Phys. Anthropol. PY 2013 VL 150 SU 56 SI SI BP 259 EP 259 PG 1 WC Anthropology; Evolutionary Biology SC Anthropology; Evolutionary Biology GA 132BR UT WOS:000318043202333 ER PT J AU Kasuya, Y Kendall, J AF Kasuya, Yuko Kendall, John BE Kasuya, Y TI Afghanistan's Strong President and Weak Parties SO PRESIDENTS, ASSEMBLIES AND POLICY-MAKING IN ASIA LA English DT Article; Book Chapter C1 [Kasuya, Yuko] Keio Univ, Tokyo, Japan. [Kendall, John] USA, Washington, DC USA. [Kendall, John] Stanford Univ, Dept Polit Sci, Stanford, CA 94305 USA. RP Kasuya, Y (reprint author), Keio Univ, Tokyo, Japan. NR 36 TC 0 Z9 0 U1 0 U2 0 PU PALGRAVE PI BASINGSTOKE PA HOUNDMILLS, BASINGSTOKE RG21 6XS, ENGLAND BN 978-1-137-31508-3 PY 2013 BP 59 EP 88 D2 10.1057/9781137315083 PG 30 WC Political Science; Public Administration SC Government & Law; Public Administration GA BFF27 UT WOS:000319617200004 ER PT J AU Darter, BJ Rodriguez, KM Wilken, JM AF Darter, Benjamin J. Rodriguez, Kelly M. Wilken, Jason M. TI Test-Retest Reliability and Minimum Detectable Change Using the K4b(2): Oxygen Consumption, Gait Efficiency, and Heart Rate for Healthy Adults During Submaximal Walking SO RESEARCH QUARTERLY FOR EXERCISE AND SPORT LA English DT Article DE exercise test; gait; reproducibility of results ID METABOLIC MEASUREMENT SYSTEM; PORTABLE GAS ANALYZER; COSMED K4 B(2); TREADMILL EXERCISE; CEREBRAL-PALSY; VARIABILITY; VALIDATION; ACCURACY; REPRODUCIBILITY; RESPONSES AB Purpose: Oxygen consumption (VO2; mLO(2)/kg/min), gait efficiency (GE; mlO(2)/kg/m) and heart rate (HR; beats per minute) are measures of physiological gait performance. However, the collection device, procedures for data normalization, and biological factors can affect measurement variability. The purpose of this study was to determine the test- retest reliability and minimum detectable change (MDC) for VO2, GE, and HR with the K4b(2) at submaximal walking speeds in healthy young adults. A second purpose was to determine if net measures improved reproducibility. Method: Twenty- two participants completed 2 identical treadmill tests on separate days at submaximal walking speeds from 0.71 m/s to 1.65 m/s. Results: Intraclass correlation coefficient (ICC) values for gross VO2, gross GE, and HR were greater than.85 for all walking speeds. Associated MDC values were approximately 7% to 10% for gross VO2 and GE, and approximately 9% to 12% for HR. ICC values for resting VO2 were lower, with MDC values approaching 25%. Subtracting out resting values to derive net VO2 and GE values produced ICC values below. 76 for the 2 slowest speeds but ICC values greater than.83 for the faster speeds. MDC values for net VO2 and GE were up to 20% for the slowest speeds. Conclusions: The results demonstrate metabolic cost can be assessed reliably using the K4b(2) during submaximal walking and that gross measures are more reliable than net measures. Furthermore, changes at self- selected speeds exceeding 1.0 mLO(2)/kg/min in gross VO2 and 0.01 mLO(2)/kg/m in gross GE can be considered a true change in walking performance. C1 [Darter, Benjamin J.] Virginia Commonwealth Univ, Richmond, VA 23298 USA. [Darter, Benjamin J.; Rodriguez, Kelly M.; Wilken, Jason M.] Brooke Army Med Ctr, Ft Sam Houston, TX 78234 USA. RP Darter, BJ (reprint author), Virginia Commonwealth Univ, Dept Phys Therapy, 1200 East Broad St,POB 980224, Richmond, VA 23298 USA. EM bjdarter@vcu.edu OI Wilken, Jason/0000-0002-5556-7667 FU Military Amputee Research Program from the National Center for Advancing Translational Sciences; Clinical and Translational Science Award from the National Center for Advancing Translational Sciences [KL2TR000057] FX Support for this project was provided by the Military Amputee Research Program through grant awards to the authors (BJD, JMW) and by Clinical and Translational Science Award No. KL2TR000057 from the National Center for Advancing Translational Sciences (BD). NR 37 TC 8 Z9 8 U1 0 U2 8 PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD PI ABINGDON PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND SN 0270-1367 J9 RES Q EXERCISE SPORT JI Res. Q. Exerc. Sport PY 2013 VL 84 IS 2 BP 223 EP 231 DI 10.1080/02701367.2013.784720 PG 9 WC Hospitality, Leisure, Sport & Tourism; Psychology, Applied; Psychology; Sport Sciences SC Social Sciences - Other Topics; Psychology; Sport Sciences GA 152YS UT WOS:000319568900011 PM 23930548 ER PT S AU Habersat, DB Lelis, AJ Green, R El, M AF Habersat, Daniel B. Lelis, Aivars J. Green, R. El, M. BE Lebedev, AA Davydov, SY Ivanov, PA Levinshtein, ME TI Evaluation of PBTS and NBTS in SiC MOS Using In Situ Charge Pumping Measurements SO SILICON CARBIDE AND RELATED MATERIALS 2012 SE Materials Science Forum LA English DT Proceedings Paper CT 9th European Conference on Silicon Carbide and Related Materials (ECSCRM 2012) CY SEP 02-06, 2012 CL St Petersburg, RUSSIA SP Nitride Crystals Grp, CREE Inc, Svetlana JSC, Russian Fdn Basic Res, Off Naval Res, Epitaxial Technol Ctr, LPE, Perfect Crystals, AIXTRON, Gen Elect, Dow Corn, Govt St Petersburg DE MOSFET; reliability; BTS; charge pumping; interface traps; oxide traps ID THRESHOLD-VOLTAGE INSTABILITY; INTERFACE TRAPS; STRESS; TRANSISTORS; DEPENDENCE AB Since power devices such as DMOSFETs will operate at higher temperatures with accelerated degradation mechanisms, it is essential to understand the effects of typical operating conditions for power electronics applications. We have found that SiC MOSFETs when gate-biased at 150 degrees C show an increasing charge pumping current over time, suggesting that interface traps (or perhaps near-interface oxide traps) are being created under these conditions. This trapping increase occurs slightly above linear-with-log-time and mimics previously observed threshold voltage instabilities, though a causal relationship has not yet been determined. We found the charge trapping after 104 s of BTS increased at a rate of 1x10(11) cm(-2)/dec for NBTS (-3 MV/cm), 0.7x10(11) cm(-2)/dec for PBTS (3 MV/cm), and 0.3x10(11) cm(-2)/dec when grounded. The observed increase in charge trapping has negative implications for the long term stability and reliability of SiC MOS devices under operating conditions. C1 [Habersat, Daniel B.; Lelis, Aivars J.; Green, R.; El, M.] USA, Res Lab, Adelphi, MD 20783 USA. RP Habersat, DB (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM daniel.b.habersat.civ@mail.mil; aivars.j.lelis.civ@mail.mil; ronald.green39.civ@mail.mil; mooro.i.el.civ@mail.mil NR 13 TC 5 Z9 5 U1 1 U2 6 PU TRANS TECH PUBLICATIONS LTD PI STAFA-ZURICH PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND SN 0255-5476 J9 MATER SCI FORUM PY 2013 VL 740-742 BP 545 EP 548 DI 10.4028/www.scientific.net/MSF.740-742.545 PG 4 WC Crystallography; Materials Science, Multidisciplinary SC Crystallography; Materials Science GA BFG56 UT WOS:000319785500128 ER PT S AU Green, R Lelis, AJ El, M Habersat, DB AF Green, Ron Lelis, A. J. El, M. Habersat, D. B. BE Lebedev, AA Davydov, SY Ivanov, PA Levinshtein, ME TI A Study of High Temperature DC and AC Gate Stressing on the Performance and Reliability of Power SiC MOSFETs SO SILICON CARBIDE AND RELATED MATERIALS 2012 SE Materials Science Forum LA English DT Proceedings Paper CT 9th European Conference on Silicon Carbide and Related Materials (ECSCRM 2012) CY SEP 02-06, 2012 CL St Petersburg, RUSSIA SP Nitride Crystals Grp, CREE Inc, Svetlana JSC, Russian Fdn Basic Res, Off Naval Res, Epitaxial Technol Ctr, LPE, Perfect Crystals, AIXTRON, Gen Elect, Dow Corn, Govt St Petersburg DE MOSFET; reliability; BTS; interface traps; oxide traps ID THRESHOLD-VOLTAGE INSTABILITY; DEPENDENCE AB Although high-temperature measurements show a dramatic reduction in the bias-temperature stress-induced threshold-voltage instability of present state-of-the-art devices, a more thorough test methodology shows that several different conclusions may actually be drawn. The particular conclusion depends on the specific post-BTS measurement technique employed. Immediate room-temperature measurements suggest that significant oxide-trap activation may still be occurring. A significant, yet rapid, post-BTS recovery is observed as well. These results underline the importance of making both high-temperature and room-temperature measurements, as a function of stress and recovery time, to better ensure that the full effect of the BTS is observed. Initial AC BTS results suggest a similar level of device degradation as occurs from a DC BTS. C1 [Green, Ron; Lelis, A. J.; El, M.; Habersat, D. B.] USA, Res Lab, Adelphi, MD 20783 USA. RP Green, R (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM ronald.green39.civ@mail.mil; aivars.j.lelis.civ@mail.mil; mooro.i.el.civ@mail.mil; daniel.b.habersat.civ@mail.mil NR 11 TC 9 Z9 9 U1 1 U2 8 PU TRANS TECH PUBLICATIONS LTD PI STAFA-ZURICH PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND SN 0255-5476 J9 MATER SCI FORUM PY 2013 VL 740-742 BP 549 EP 552 DI 10.4028/www.scientific.net/MSF.740-742.549 PG 4 WC Crystallography; Materials Science, Multidisciplinary SC Crystallography; Materials Science GA BFG56 UT WOS:000319785500129 ER PT S AU Veliadis, V Snook, M Hearne, H Nechay, B Woodruff, S Lavoie, C Kirby, C Imhoff, E White, J Davis, S AF Veliadis, V. Snook, M. Hearne, H. Nechay, B. Woodruff, S. Lavoie, C. Kirby, C. Imhoff, E. White, J. Davis, S. BE Lebedev, AA Davydov, SY Ivanov, PA Levinshtein, ME TI Process Tolerant Single Photolithography/Implantation 120-Zone Junction Termination Extension SO SILICON CARBIDE AND RELATED MATERIALS 2012 SE Materials Science Forum LA English DT Proceedings Paper CT 9th European Conference on Silicon Carbide and Related Materials (ECSCRM 2012) CY SEP 02-06, 2012 CL Saint Petersburg, RUSSIA SP Nitride Crystals Grp, CREE Inc, Svetlana JSC, Russian Fdn Basic Res, Off Naval Res, Epitaxial Technol Ctr, LPE, Perfect Crystals, AIXTRON, Gen Elect, Dow Corn, Govt St Petersburg DE Junction termination extension; JTE; multiple-zone JTE; edge termination; single implant; single photolithography; blocking voltage; high voltage; diode; silicon carbide; SiC; PiN ID VOLTAGE SIC DEVICES AB The multiple-zone junction termination extension (MJTE) is a widely used SiC edge termination technique that reduces sensitivity to implantation dose variations. It is typically implemented in multiple lithography and implantation events. To reduce process complexity, cycle time, and cost, a single photolithography/implantation (P/I) MJTE technique was developed and diodes with 3-zone and 120-zone JTEs were fabricated on the same wafer. Here, the process tolerance of the single (P/I) MJTE technique is evaluated by performing CCD monitored blocking voltage measurements on diodes from the same wafer with the 3-zone and 120-zone single (P/I) JTE. The 3-zone JTE diodes exhibited catastrophic localized avalanches at the interface between the 2nd and 3rd zones due to abrupt zone transitions. Diodes with the smooth transitioning 120-zone JTE exhibited no CCD detectable avalanches in their JTE regions up to the testing limit of 12 kV. Under thick dielectric (deposited for on-wafer diode interconnection), diodes with the single P/I 3-zone JTE failed due to significant loss of high-voltage capability, while their 120-zone JTE diode counterparts were minimally affected. Overall, the single (P/I) 120-zone JTE provides a process-tolerant and robust single P/I edge termination at no additional fabrication labor. C1 [Veliadis, V.; Snook, M.; Hearne, H.; Nechay, B.; Woodruff, S.; Lavoie, C.; Kirby, C.] Northrop Grumman Elect Syst, Linthicum, MD 21090 USA. [Imhoff, E.] US Naval Acad, Res Lab, Washington, DC 20375 USA. [White, J.; Davis, S.] US Army, TARDEC, Warren, MI 48397 USA. RP Veliadis, V (reprint author), Northrop Grumman Elect Syst, Linthicum, MD 21090 USA. EM victor.veliadis@ngc.com; eugene.imhoff@nrl.navy.mil; stuart.m.davis.civ@mail.mil NR 6 TC 1 Z9 1 U1 0 U2 3 PU TRANS TECH PUBLICATIONS LTD PI DURNTEN-ZURICH PA KREUZSTRASSE 10, 8635 DURNTEN-ZURICH, SWITZERLAND SN 0255-5476 J9 MATER SCI FORUM PY 2013 VL 740-742 BP 855 EP + DI 10.4028/www.scientific.net/MSF.740-742.855 PG 2 WC Crystallography; Materials Science, Multidisciplinary SC Crystallography; Materials Science GA BFG56 UT WOS:000319785500204 ER PT S AU Cheng, L Agarwal, AK O'Loughlin, M Capell, C Lam, K Jonas, C Richmond, J Burk, A Palmour, JW Ogunniyi, AA O'Brien, HK Scozzie, CJ AF Cheng, Lin Agarwal, Anant K. O'Loughlin, Michael Capell, Craig Lam, Khiem Jonas, Charlotte Richmond, Jim Burk, Al Palmour, John W. Ogunniyi, Aderinto A. O'Brien, Heather K. Scozzie, Charles J. BE Lebedev, AA Davydov, SY Ivanov, PA Levinshtein, ME TI 16 kV, 1 cm(2), 4H-SiC PiN Diodes for Advanced High-Power and High-Temperature Applications SO SILICON CARBIDE AND RELATED MATERIALS 2012 SE Materials Science Forum LA English DT Proceedings Paper CT 9th European Conference on Silicon Carbide and Related Materials (ECSCRM 2012) CY SEP 02-06, 2012 CL Saint Petersburg, RUSSIA SP Nitride Crystals Grp, CREE Inc, Svetlana JSC, Russian Fdn Basic Res, Off Naval Res, Epitaxial Technol Ctr, LPE, Perfect Crystals, AIXTRON, Gen Elect, Dow Corn, Govt St Petersburg DE PiN diode; high voltage; silicon carbide; carrier lifetime; high injection-current density; high temperature AB In this work, we report our recently developed 16 kV, 1 cm(2), 4H-SiC PiN diode results. The SiC PiN diode was built on a 120 mu m, 2x10(14)/cm(3) doped n-type SiC drift layer with a device active area of 0.5175 cm(2). Forward conduction of the PiN diode was characterized at temperatures from 20 degrees C to 200 degrees C. At high injection-current density (J(F)) of 350 similar to 400 A/cm(2), the differential on-resistance (R-ON,R-diff) of the SiC PiN diode decreased from 6.08 m Omega.cm(2) at 20 degrees C to 5.12 m Omega.cm(2) at 200 degrees C, resulting in a very small average temperature coefficient of -5.33 mu Omega.cm(2)/degrees C, while the forward voltage drop (V-F) at 100 A/cm(2) reduced from 4.77 V at 20 degrees C to 4.17 V at 200 degrees C. This is due to an increasing high-level carrier lifetime with an increase in temperature, resulting in reduced forward voltage drop. We also observed lower R-ON,R-diff at higher injection-current densities, suggesting that a higher carrier lifetime is needed in this lightly doped n-type SiC thick epi-layer in order to achieve full conductivity modulation. The anode to cathode reverse blocking leakage current was measured as 0.9 mu A at 16 kV at room temperature. C1 [Cheng, Lin; Agarwal, Anant K.; O'Loughlin, Michael; Capell, Craig; Lam, Khiem; Jonas, Charlotte; Richmond, Jim; Burk, Al; Palmour, John W.] Cree Inc, 4600 Silicon Dr, Durham, NC 27703 USA. [Ogunniyi, Aderinto A.; O'Brien, Heather K.; Scozzie, Charles J.] US Army, Res Lab, Adelphi, MD 20783 USA. RP Cheng, L (reprint author), Cree Inc, 4600 Silicon Dr, Durham, NC 27703 USA. EM lin_cheng@cree.com FU US Army Research Laboratory in Ade lphi, MD, USA [W911NF-04-2-0022] FX This research was funded through the Cooperative Agreement W911NF-04-2-0022 supported by the US Army Research Laboratory in Ade lphi, MD, USA. NR 3 TC 7 Z9 7 U1 0 U2 8 PU TRANS TECH PUBLICATIONS LTD PI DURNTEN-ZURICH PA KREUZSTRASSE 10, 8635 DURNTEN-ZURICH, SWITZERLAND SN 0255-5476 J9 MATER SCI FORUM PY 2013 VL 740-742 BP 895 EP + DI 10.4028/www.scientific.net/MSF.740-742.895 PG 2 WC Crystallography; Materials Science, Multidisciplinary SC Crystallography; Materials Science GA BFG56 UT WOS:000319785500213 ER PT S AU Steiner, B Bayne, SB Veliadis, V Ha, HC Urciuoli, D El-Hinnawy, N Borodulin, P Scozzie, C AF Steiner, B. Bayne, S. B. Veliadis, V. Ha, H. C. Urciuoli, D. El-Hinnawy, N. Borodulin, P. Scozzie, C. BE Lebedev, AA Davydov, SY Ivanov, PA Levinshtein, ME TI Reliable Operation of SiC Junction-Field-Effect-Transistor Subjected to Over 2 Million 600-V Hard Switch Stressing Events SO SILICON CARBIDE AND RELATED MATERIALS 2012 SE Materials Science Forum LA English DT Proceedings Paper CT 9th European Conference on Silicon Carbide and Related Materials (ECSCRM 2012) CY SEP 02-06, 2012 CL Saint Petersburg, RUSSIA SP Nitride Crystals Grp, CREE Inc, Svetlana JSC, Russian Fdn Basic Res, Off Naval Res, Epitaxial Technol Ctr, LPE, Perfect Crystals, AIXTRON, Gen Elect, Dow Corn, Govt St Petersburg DE JFET; 4H-SiC; vertical channel; normally-ON; 1200-V; bidirectional; fault isolation; four quadrant; reliability; hard switching; pulsing; high temperature; high voltage ID VERTICAL-CHANNEL JFETS; POWER AB A necessity for the successful commercialization of SiC power devices is their long term reliability under the switching conditions encountered in the field. Normally-ON 1200 V SiC JFETs were stressed in repetitive hard-switching conditions to determine their fault handling capabilities. The switching pulses were generated from an RLC circuit, where energy initially stored in capacitors discharges through the JFET into a resistive load. The hard-switching included one million repetitive pulsed hard-switching events at 25 degrees C from a drain blocking-voltage of 600 V to an on-state current of 67 A, and an additional one million 600-V/63-A pulsed hard-switching events at 150 degrees C. The JFET conduction and blocking-voltage characteristics are virtually unchanged after over two million hard switching events proving the devices are reliable for handling high surge-current faults like those encountered in bidirectional circuit breaker applications. C1 [Steiner, B.; Bayne, S. B.] Texas Tech Univ, Ctr Pulsed Power & Power Elect, Lubbock, TX 79409 USA. [Veliadis, V.; Ha, H. C.; El-Hinnawy, N.; Borodulin, P.] Northrop Grumman Elect Syst, Linthicunn, MD 21090 USA. [Urciuoli, D.; Scozzie, C.] US Army Res Lab, Ade Iphi, MD 20783 USA. RP Steiner, B (reprint author), Texas Tech Univ, Ctr Pulsed Power & Power Elect, Lubbock, TX 79409 USA. EM stephen.bayne@ttu.edu; victor.veliadis@ngc.com; damian.p.urciuoli.civ@mail.mil NR 11 TC 1 Z9 1 U1 0 U2 3 PU TRANS TECH PUBLICATIONS LTD PI DURNTEN-ZURICH PA KREUZSTRASSE 10, 8635 DURNTEN-ZURICH, SWITZERLAND SN 0255-5476 J9 MATER SCI FORUM PY 2013 VL 740-742 BP 921 EP + DI 10.4028/www.scientific.net/MSF.740-742.921 PG 2 WC Crystallography; Materials Science, Multidisciplinary SC Crystallography; Materials Science GA BFG56 UT WOS:000319785500219 ER PT S AU Cheng, L Agarwal, AK Capell, C O'Loughlin, M Lam, K Zhang, J Richmond, J Burk, A Palmour, JW Ogunniyi, AA O'Brien, HK Scozzie, CJ AF Cheng, Lin Agarwal, Anant K. Capell, Craig O'Loughlin, Michael Lam, Khiem Zhang, Jon Richmond, Jim Burk, Al Palmour, John W. Ogunniyi, Aderinto A. O'Brien, Heather K. Scozzie, Charles J. BE Lebedev, AA Davydov, SY Ivanov, PA Levinshtein, ME TI 15 kV, Large Area (1 cm(2)), 4H-SiC p-Type Gate Turn-Off Thyristors SO SILICON CARBIDE AND RELATED MATERIALS 2012 SE Materials Science Forum LA English DT Proceedings Paper CT 9th European Conference on Silicon Carbide and Related Materials (ECSCRM 2012) CY SEP 02-06, 2012 CL Saint Petersburg, RUSSIA SP Nitride Crystals Grp, CREE Inc, Svetlana JSC, Russian Fdn Basic Res, Off Naval Res, Epitaxial Technol Ctr, LPE, Perfect Crystals, AIXTRON, Gen Elect, Dow Corn, Govt St Petersburg DE gate turn-off thyristor; GTO; high voltage; silicon carbide; carrier lifetime; high injection-current; high temperature AB In this paper, we report our recently developed 1 cm(2), 15 kV SiC p-GTO with an extremely low differential on-resistance (R-ON,R-diff) of 4.08 m Omega.cm(2) at a high injection-current density (J(AK)) of 600 similar to 710 A/cm(2). The 15 kV SiC p-GTO was built on a 120 mu m, 2x10(14)/cm(3) doped p-type SiC drift layer with a device active area of 0.521 cm(2). Forward conduction of the 15 kV SiC p-GTO was characterized at 20 degrees C and 200 degrees C. Over this temperature range, the R-ON,R-diff at J(AK) of 600 similar to 710 A/cm(2) decreased from 4.08 m Omega.cm(2) at 20 degrees C to 3.45 m Omega.cm(2) at J(AK) of 600 similar to 680 A/cm(2) at 200 degrees C. The gate to cathode blocking voltage (V-GK) was measured using a customized high-voltage test setup. The leakage current at a V-GK of 15 kV were measured 0.25 mu A and 0.41 mu A at 20 degrees C and 200 degrees C respectively. C1 [Cheng, Lin; Agarwal, Anant K.; Capell, Craig; O'Loughlin, Michael; Lam, Khiem; Zhang, Jon; Richmond, Jim; Burk, Al; Palmour, John W.] Cree Inc, 4600 Silicon Dr, Durham, NC 27703 USA. [Ogunniyi, Aderinto A.; O'Brien, Heather K.; Scozzie, Charles J.] US Army, Res Lab, Adelphi, MD 20783 USA. RP Cheng, L (reprint author), Cree Inc, 4600 Silicon Dr, Durham, NC 27703 USA. EM lin_cheng@cree.com FU Army Research Laboratory, Adelphi, Maryland FX The authors would like to acknowledge the funding support from Army Research Laboratory, Adelphi, Maryland for the work on SiC GTOs. NR 5 TC 18 Z9 18 U1 0 U2 6 PU TRANS TECH PUBLICATIONS LTD PI DURNTEN-ZURICH PA KREUZSTRASSE 10, 8635 DURNTEN-ZURICH, SWITZERLAND SN 0255-5476 J9 MATER SCI FORUM PY 2013 VL 740-742 BP 978 EP + DI 10.4028/www.scientific.net/MSF.740-742.978 PG 2 WC Crystallography; Materials Science, Multidisciplinary SC Crystallography; Materials Science GA BFG56 UT WOS:000319785500233 ER PT B AU Zhang, DF Ge, LQ Hardy, R Yu, W Zhang, HL Reschly, R AF Zhang, Difan Ge, Linqiang Hardy, Rommie Yu, Wei Zhang, Hanlin Reschly, Robert GP IEEE TI On Effective Data Aggregation Techniques In Host-based Intrusion Detection in MANET SO 2013 IEEE CONSUMER COMMUNICATIONS AND NETWORKING CONFERENCE (CCNC) LA English DT Proceedings Paper CT 10th IEEE Consumer Communications and Networking Conference (CCNC) CY JAN 11-14, 2013 CL Las Vegas, NV SP IEEE ID AD HOC NETWORKS; SECURITY ISSUES AB Mobile Ad Hoc Networks (MANETs) have been widely used in commercial and tactical domains. MANETs commonly demand a robust, diverse, energy-efficient, and resilient communication and computing infrastructure, enabling network-centric operation with minimal downtime. MANETs face security risks and energy consumption. However, conducting cyber attack monitoring and detection in a MANET becomes a challenging issue because of limited resources and its infrastructureless network environment. To address this issue, we develop both lossless and lossy aggregation techniques to reduce the energy cost in information transition and bandwidth consumption while preserving the desired detection accuracy. In particular, we develop two lossless aggregation techniques: compression-based and event-based aggregation and develop a lossy aggregation technique: feature-based aggregation. We conduct real-world experiments and simulation study to evaluate the effectiveness of our proposed data aggregation techniques in terms of the energy consumption and detection accuracy. C1 [Zhang, Difan; Ge, Linqiang; Yu, Wei; Zhang, Hanlin] Towson Univ, Towson, MD 21252 USA. [Hardy, Rommie; Reschly, Robert] U S Army Res Lab, Adelphi, MD USA. RP Zhang, DF (reprint author), Towson Univ, Towson, MD 21252 USA. EM cheungtifan@gmail.com; lge2@students.towson.edu; rommie.l.hardy.civ@mail.mil; wyu@towson.edu; hzhang4@students.towson.edu; robert.j.reschly.civ@mail.mil OI Zhang, Hanlin/0000-0001-8869-6863 FU US Army Research Laboratory (ARL) [W911NF-111-0193] FX This work was supported in part by the US Army Research Laboratory (ARL) under grant W911NF-111-0193. Any opinions, findings and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the US funding agencies. NR 9 TC 1 Z9 1 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4673-3133-3; 978-1-4673-4735-8 PY 2013 BP 85 EP 90 PG 6 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BEZ77 UT WOS:000318943600013 ER PT J AU Song, HJ Wang, Y Rosano, JM Prabhakarpandian, B Garson, C Pant, K Lai, E AF Song, Hongjun Wang, Yi Rosano, Jenna M. Prabhakarpandian, Balabhaskar Garson, Charles Pant, Kapil Lai, Eva TI A microfluidic impedance flow cytometer for identification of differentiation state of stem cells SO LAB ON A CHIP LA English DT Article ID RED-BLOOD-CELLS; TISSUE-CULTURE; MAMMALIAN-CELLS; SPECTROSCOPY; BIOSENSOR; BEHAVIOR; COUNTER; DEVICE; SENSOR; LINES AB This paper presents a microfluidic electrical impedance flow cytometer (FC) for identifying the differentiation state of single stem cells. This device is comprised of a novel dual micropore design, which not only enhances the processing throughput, but also allows the associated electrodes to be used as a reference for one another. A signal processing algorithm, based on the support vector machine (SVM) theory, and a data classification method were developed to automate the identification of sample types and cell differentiation state based on measured impedance values. The device itself was fabricated using a combination of standard and soft lithography techniques to generate a PDMS-gold electrode construct. Experimental testing with non-biological particles and mouse embryonic carcinoma cells (P19, undifferentiated and differentiated) was carried out using a range of excitation frequencies. The effects of the frequency and the interrogation parameters on sample identification performance were investigated. It was found that the real and imaginary part of the detected impedance signal were adequate for distinguishing the undifferentiated P19 cells from non-biological polystyrene beads at all tested frequencies. A higher frequency and an opacity index were required to resolve the undifferentiated and differentiated P19 cells by capturing capacitive changes in electrophysiological properties arising from differentiation. The experimental results demonstrated salient accuracy of the device and algorithm, and established its feasibility for non-invasive, label-free identification of the differentiation state of the stem cells. C1 [Song, Hongjun; Wang, Yi; Rosano, Jenna M.; Prabhakarpandian, Balabhaskar; Garson, Charles; Pant, Kapil] CFD Res Corp, Huntsville, AL 35805 USA. [Lai, Eva] Johns Hopkins Univ, Dept Chem & Biomol Engn, Baltimore, MD 21218 USA. [Lai, Eva] USA, Telemed & Adv Technol Res Ctr, Med Res & Mat Command USAMRMC, Ft Detrick, MD 21702 USA. RP Wang, Y (reprint author), CFD Res Corp, 215 Wynn Dr, Huntsville, AL 35805 USA. EM yxw@cfdrc.com FU U.S. Army Medical Research and Materiel Command (USAMRMC) under SBIR [W81XWH-12-C-0069] FX This research was sponsored by the U.S. Army Medical Research and Materiel Command (USAMRMC) under SBIR contract No. W81XWH-12-C-0069. NR 41 TC 35 Z9 35 U1 6 U2 57 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 1473-0197 J9 LAB CHIP JI Lab Chip PY 2013 VL 13 IS 12 BP 2300 EP 2310 DI 10.1039/c3lc41321g PG 11 WC Biochemical Research Methods; Chemistry, Multidisciplinary; Nanoscience & Nanotechnology SC Biochemistry & Molecular Biology; Chemistry; Science & Technology - Other Topics GA 148YS UT WOS:000319285500011 PM 23636706 ER PT J AU Lossie, C AF Lossie, Cheryl BE Malhotra, S Rowe, AC TI Hear I Meet the Silence: The Wise Pedagogue SO SILENCE, FEMINISM, POWER: REFLECTIONS AT THE EDGES OF SOUND LA English DT Article; Book Chapter C1 [Lossie, Cheryl] Fayetteville Tech Community Coll, Fayetteville, NC USA. [Lossie, Cheryl] USA, John F Kennedy Special Warfare Ctr & Sch, Ft Bragg, NC USA. RP Lossie, C (reprint author), Fayetteville Tech Community Coll, Fayetteville, NC USA. NR 10 TC 0 Z9 0 U1 0 U2 0 PU PALGRAVE PI BASINGSTOKE PA HOUNDMILLS, BASINGSTOKE RG21 6XS, ENGLAND BN 978-1-137-00237-2 PY 2013 BP 129 EP 138 D2 10.1057/9781137002372 PG 10 WC Sociology; Women's Studies SC Sociology; Women's Studies GA BEW03 UT WOS:000318345000010 ER PT J AU Willbanks, JH AF Willbanks, James H. BE Willbanks, JH TI GENERALS OF THE ARMY Marshall, MacArthur, Eisenhower, Arnold, Bradley Introduction SO GENERALS OF THE ARMY: MARSHALL, MACARTHUR EISENHOWER, ARNOLD, BRADLEY SE American Warriors Series LA English DT Editorial Material; Book Chapter C1 [Willbanks, James H.] USA, Army George C Marshall Chair Mil Hist, Command & Gen Staff Coll, Ft Leavenworth, KS USA. [Willbanks, James H.] USA, Dept Mil Hist, Command & Gen Staff Coll, Ft Leavenworth, KS USA. RP Willbanks, JH (reprint author), USA, Army George C Marshall Chair Mil Hist, Command & Gen Staff Coll, Ft Leavenworth, KS USA. NR 2 TC 1 Z9 2 U1 0 U2 0 PU UNIV PRESS KENTUCKY PI LEXINGTON PA 102 LAFFERTY HALL, UNIVERSITY OF KENTUCKY, LEXINGTON, KY 40506 USA BN 978-0-8131-4212-8 J9 AMER WARRIOR SER PY 2013 BP 1 EP 3 PG 3 WC History SC History GA BEU67 UT WOS:000318222200002 ER PT J AU House, JM AF House, Jonathan M. BE Willbanks, JH TI Officer Education and the Fort Leavenworth Schools, 1881-1940 SO GENERALS OF THE ARMY: MARSHALL, MACARTHUR EISENHOWER, ARNOLD, BRADLEY SE American Warriors Series LA English DT Article; Book Chapter C1 [House, Jonathan M.] USA, Command & Gen Staff Coll, Washington, DC 20310 USA. [House, Jonathan M.] Gordon Coll, Barnesville, GA USA. RP House, JM (reprint author), USA, Command & Gen Staff Coll, Washington, DC 20310 USA. NR 7 TC 1 Z9 1 U1 0 U2 0 PU UNIV PRESS KENTUCKY PI LEXINGTON PA 102 LAFFERTY HALL, UNIVERSITY OF KENTUCKY, LEXINGTON, KY 40506 USA BN 978-0-8131-4212-8 J9 AMER WARRIOR SER PY 2013 BP 5 EP 18 PG 14 WC History SC History GA BEU67 UT WOS:000318222200003 ER PT B AU Sullivan, GR AF Sullivan, Gordon R. BE Willbanks, JH TI GENERALS OF THE ARMY Marshall, MacArthur, Eisenhower, Arnold, Bradley Foreword SO GENERALS OF THE ARMY: MARSHALL, MACARTHUR EISENHOWER, ARNOLD, BRADLEY SE American Warriors Series LA English DT Editorial Material; Book Chapter C1 [Sullivan, Gordon R.] USA, Washington, DC USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU UNIV PRESS KENTUCKY PI LEXINGTON PA 102 LAFFERTY HALL, UNIVERSITY OF KENTUCKY, LEXINGTON, KY 40506 USA BN 978-0-8131-4212-8 J9 AMER WARRIOR SER PY 2013 BP XI EP XI PG 1 WC History SC History GA BEU67 UT WOS:000318222200001 ER PT B AU Gabel, CR AF Gabel, Christopher R. BE Willbanks, JH TI George Catlett Marshall SO GENERALS OF THE ARMY: MARSHALL, MACARTHUR EISENHOWER, ARNOLD, BRADLEY SE American Warriors Series LA English DT Article; Book Chapter C1 [Gabel, Christopher R.] USA, Command & Gen Staff Coll, Ft Leavenworth, KS USA. NR 11 TC 0 Z9 0 U1 0 U2 0 PU UNIV PRESS KENTUCKY PI LEXINGTON PA 102 LAFFERTY HALL, UNIVERSITY OF KENTUCKY, LEXINGTON, KY 40506 USA BN 978-0-8131-4212-8 J9 AMER WARRIOR SER PY 2013 BP 19 EP 61 PG 43 WC History SC History GA BEU67 UT WOS:000318222200004 ER PT J AU Mullis, TR AF Mullis, Tony R. BE Willbanks, JH TI Douglas MacArthur SO GENERALS OF THE ARMY: MARSHALL, MACARTHUR EISENHOWER, ARNOLD, BRADLEY SE American Warriors Series LA English DT Article; Book Chapter C1 [Mullis, Tony R.] USA, Dept Mil Hist, Command & Gen Staff Coll, Ft Leavenworth, KS USA. [Mullis, Tony R.] USAF Acad, Maxwell AFB, AL USA. [Mullis, Tony R.] Air Command & Staff Coll, Maxwell AFB, AL USA. [Mullis, Tony R.] Univ Maryland, Baltimore, MD USA. [Mullis, Tony R.] Troy Univ, Troy, AL USA. [Mullis, Tony R.] Benedictine Coll, Atchison, KS 66002 USA. [Mullis, Tony R.] Tiffin Univ, Tiffin, OH USA. [Mullis, Tony R.] Auburn Univ, Montgomery, AL 36117 USA. RP Mullis, TR (reprint author), USA, Dept Mil Hist, Command & Gen Staff Coll, Ft Leavenworth, KS USA. NR 31 TC 0 Z9 0 U1 0 U2 0 PU UNIV PRESS KENTUCKY PI LEXINGTON PA 102 LAFFERTY HALL, UNIVERSITY OF KENTUCKY, LEXINGTON, KY 40506 USA BN 978-0-8131-4212-8 J9 AMER WARRIOR SER PY 2013 BP 63 EP 111 PG 49 WC History SC History GA BEU67 UT WOS:000318222200005 ER PT B AU Kalic, SN AF Kalic, Sean N. BE Willbanks, JH TI Dwight D. Eisenhower SO GENERALS OF THE ARMY: MARSHALL, MACARTHUR EISENHOWER, ARNOLD, BRADLEY SE American Warriors Series LA English DT Article; Book Chapter C1 USA, Dept Mil Hist, Command & Gen Staff Coll, Ft Leavenworth, KS USA. RP Kalic, SN (reprint author), USA, Dept Mil Hist, Command & Gen Staff Coll, Ft Leavenworth, KS USA. NR 17 TC 0 Z9 0 U1 0 U2 0 PU UNIV PRESS KENTUCKY PI LEXINGTON PA 102 LAFFERTY HALL, UNIVERSITY OF KENTUCKY, LEXINGTON, KY 40506 USA BN 978-0-8131-4212-8 J9 AMER WARRIOR SER PY 2013 BP 113 EP 145 PG 33 WC History SC History GA BEU67 UT WOS:000318222200006 ER PT B AU Curatola, JM AF Curatola, John M. BE Willbanks, JH TI Henry H. "Hap" Arnold SO GENERALS OF THE ARMY: MARSHALL, MACARTHUR EISENHOWER, ARNOLD, BRADLEY SE American Warriors Series LA English DT Article; Book Chapter C1 [Curatola, John M.] USA, Command & Gen Staff Coll, Ft Leavenworth, KS USA. RP Curatola, JM (reprint author), USA, Command & Gen Staff Coll, Ft Leavenworth, KS USA. NR 14 TC 0 Z9 0 U1 0 U2 0 PU UNIV PRESS KENTUCKY PI LEXINGTON PA 102 LAFFERTY HALL, UNIVERSITY OF KENTUCKY, LEXINGTON, KY 40506 USA BN 978-0-8131-4212-8 J9 AMER WARRIOR SER PY 2013 BP 147 EP 182 PG 36 WC History SC History GA BEU67 UT WOS:000318222200007 ER PT J AU Fischer, JR AF Fischer, Joseph R. BE Willbanks, JH TI Omar Nelson Bradley SO GENERALS OF THE ARMY: MARSHALL, MACARTHUR EISENHOWER, ARNOLD, BRADLEY SE American Warriors Series LA English DT Article; Book Chapter C1 [Fischer, Joseph R.] USA, Dept Mili Hist, Command & Gen Staff Coll, Ft Leavenworth, KS USA. [Fischer, Joseph R.] US Mil Acad, West Point, NY USA. [Fischer, Joseph R.] Penn State, PhD Program Amer Hist, University Pk, PA USA. RP Fischer, JR (reprint author), USA, Dept Mili Hist, Command & Gen Staff Coll, Ft Leavenworth, KS USA. NR 15 TC 0 Z9 0 U1 0 U2 0 PU UNIV PRESS KENTUCKY PI LEXINGTON PA 102 LAFFERTY HALL, UNIVERSITY OF KENTUCKY, LEXINGTON, KY 40506 USA BN 978-0-8131-4212-8 J9 AMER WARRIOR SER PY 2013 BP 183 EP 231 PG 49 WC History SC History GA BEU67 UT WOS:000318222200008 ER PT B AU Rafuse, ES AF Rafuse, Ethan S. BE Willbanks, JH TI GENERALS OF THE ARMY Marshall, MacArthur, Eisenhower, Arnold, Bradley Afterword SO GENERALS OF THE ARMY: MARSHALL, MACARTHUR EISENHOWER, ARNOLD, BRADLEY SE American Warriors Series LA English DT Editorial Material; Book Chapter C1 USA, Command & Gen Staff Coll, Ft Leavenworth, KS USA. RP Rafuse, ES (reprint author), USA, Command & Gen Staff Coll, Ft Leavenworth, KS USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU UNIV PRESS KENTUCKY PI LEXINGTON PA 102 LAFFERTY HALL, UNIVERSITY OF KENTUCKY, LEXINGTON, KY 40506 USA BN 978-0-8131-4212-8 J9 AMER WARRIOR SER PY 2013 BP 233 EP 236 PG 4 WC History SC History GA BEU67 UT WOS:000318222200009 ER PT J AU Nkansah-Amankra, S Agbanu, SK Miller, RJ AF Nkansah-Amankra, Stephen Agbanu, Samuel Kwami Miller, Reuben Jonathan TI DISPARITIES IN HEALTH, POVERTY, INCARCERATION, AND SOCIAL JUSTICE AMONG RACIAL GROUPS IN THE UNITED STATES: A CRITICAL REVIEW OF EVIDENCE OF CLOSE LINKS WITH NEOLIBERALISM SO INTERNATIONAL JOURNAL OF HEALTH SERVICES LA English DT Article ID PUBLIC-HEALTH; AFRICAN-AMERICANS; FUNDAMENTAL CAUSES; INCOME INEQUALITY; SINGLE MOTHERS; NEO-LIBERALISM; CARE; RACE; POLICY; POLITICS AB Problems of poverty, poor health, and incarceration are unevenly distributed among racial and ethnic minorities in the United States. We argue that this is due, in part, to the ascendance of United States-style neoliberalism, a prevailing political and economic doctrine that shapes social policy, including public health and anti-poverty intervention strategies. Public health research most often associates inequalities in health outcomes, poverty, and incarceration with individual and cultural risk factors. Contextual links to structural inequality and the neoliberal doctrine animating state-sanctioned interventions are given less attention. The interrelationships among these are not clear in the extant literature. Less is known about public health and incarceration. Thus, the authors describe the linkages between neoliberalism, public health, and criminal justice outcomes. We suggest that neoliberalism exacerbates racial disparities in health, poverty, and incarceration in the United States. We conclude by calling for a new direction in public health research that advances a pro-poor public health agenda to improve the general well-being of disadvantaged groups. C1 [Nkansah-Amankra, Stephen] Cent Michigan Univ, Grace A & Herbert H Coll Hlth Profess, Sch Hlth Sci, Mt Pleasant, MI 48858 USA. [Agbanu, Samuel Kwami] USA, Washington, DC USA. [Miller, Reuben Jonathan] Loyola Univ Chicago, Dept Sociol, Chicago, IL USA. RP Nkansah-Amankra, S (reprint author), Cent Michigan Univ, Grace A & Herbert H Coll Hlth Profess, Sch Hlth Sci, 2209 Hlth Profess Bldg, Mt Pleasant, MI 48858 USA. EM nkans1s@cmich.edu NR 123 TC 4 Z9 4 U1 4 U2 36 PU BAYWOOD PUBL CO INC PI AMITYVILLE PA 26 AUSTIN AVE, PO BOX 337, AMITYVILLE, NY 11701 USA SN 0020-7314 J9 INT J HEALTH SERV JI Int. J. Health Serv. PY 2013 VL 43 IS 2 BP 217 EP 240 DI 10.2190/HS.43.2.c PG 24 WC Health Care Sciences & Services; Health Policy & Services SC Health Care Sciences & Services GA 142GY UT WOS:000318786600003 PM 23821903 ER PT J AU Nergiz, SZ Gandra, N Farrell, ME Tian, LM Pellegrino, PM Singamaneni, S AF Nergiz, Saide Z. Gandra, Naveen Farrell, Mikella E. Tian, Limei Pellegrino, Paul M. Singamaneni, Srikanth TI Biomimetic SERS substrate: peptide recognition elements for highly selective chemical detection in chemically complex media SO JOURNAL OF MATERIALS CHEMISTRY A LA English DT Article ID ENHANCED RAMAN-SPECTROSCOPY; GOLD NANORODS; MOLECULAR RECOGNITION; REFRACTIVE-INDEX; SURFACE; EXPLOSIVES; SCATTERING; SILVER; SIZE; TNT AB Surface enhanced Raman scattering (SERS) is rapidly emerging as a sensitive transduction platform for the trace detection of chemical and biological analytes. A critical challenge that needs to be addressed to propel this technique into real world applications is the poor chemical selectivity of the existing SERS substrates. In this communication, we demonstrate a novel biomimetic approach to enhance the selectivity of plasmonic nanostructures to target chemical analytes. In particular, we demonstrate that material-binding peptides, identified through phage-display, serve as recognition elements for selective capture of target chemical species from a complex chemical mixture. As a proof of concept, we show that a nitroaromatic explosive molecule, trinitrotoluene (TNT), can be detected down to 100 pM concentration even in a complex organic chemical mixture. This ultrasensitive and selective detection is enabled by TNT-binding peptides appended to gold nanorods, which serve as selective SERS media. To the best of our knowledge, this is the first demonstration of a biomimetic SERS substrate facilitating selective and sensitive detection of a target chemical analyte in the presence of numerous unknown interfering species. C1 [Nergiz, Saide Z.; Gandra, Naveen; Tian, Limei; Singamaneni, Srikanth] Washington Univ, Dept Mech Engn & Mat Sci, St Louis, MO 63130 USA. [Farrell, Mikella E.; Pellegrino, Paul M.] USA, Res Lab, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA. RP Nergiz, SZ (reprint author), Washington Univ, Dept Mech Engn & Mat Sci, St Louis, MO 63130 USA. EM singamaneni@wustl.edu RI Gandra, Naveen/H-6317-2011 OI Gandra, Naveen/0000-0001-8252-4374 NR 42 TC 22 Z9 22 U1 4 U2 55 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 2050-7488 J9 J MATER CHEM A JI J. Mater. Chem. A PY 2013 VL 1 IS 22 BP 6543 EP 6549 DI 10.1039/c3ta00138e PG 7 WC Chemistry, Physical; Energy & Fuels; Materials Science, Multidisciplinary SC Chemistry; Energy & Fuels; Materials Science GA 144LQ UT WOS:000318941200005 ER PT J AU Yoon, SC Windham, WR Ladely, SR Heitschmidt, JW Lawrence, KC Park, B Narang, N Cray, WC AF Yoon, Seung-Chul Windham, William R. Ladely, Scott R. Heitschmidt, Jerry W. Lawrence, Kurt C. Park, Bosoon Narang, Neelam Cray, William C. TI Hyperspectral imaging for differentiating colonies of non-0157 Shiga-toxin producing Escherichia coli (STEC) serogroups on spread plates of pure cultures SO JOURNAL OF NEAR INFRARED SPECTROSCOPY LA English DT Article DE hyperspectral imaging; Escherichia coli; STEC non-0157; pathogen detection; STEC colonies; spread plates; Rainbow agar; classification; chemometrics; data sampling ID PATHOGEN DETECTION; UNITED-STATES; CLASSIFICATION; PERSPECTIVE; PREDICTION; BIOSENSORS AB Direct plating on solid agar media has been widely used in microbiology laboratories for presumptive-positive pathogen detection, although it is often subjective and labour-intensive. Rainbow agar is a selective and differential chromogenic medium used to isolate pathogenic Escherichia coli (E. coli) strains. However, it is challenging to differentiate colonies of the six representative pathogenic non-0157 Shiga-toxin producing E. coli (STEC) serogroups (026, 045, 0103, 0111, 0121 and 0145) on Rainbow agar due to the phenotypic differences and the presence of background microflora. Therefore, there is a need for a method or technology to objectively, rapidly and accurately perform high-throughput screening of non-0157 STEC colonies on agar plates. In this paper, we report the development of a visible-near infrared hyperspectral imaging technique and prediction model for differentiating colony types of the six non-0157 STEC serogroups in spread plates of pure cultures inoculated on Rainbow agar. The prediction model was based on supervised linear classification of factor scores obtained by principal component analysis (PCA). Both PCA-MD (Mahalanobis distance) and PCA-kNN (k-nearest neighbour) classifiers were used for model development. From the 24 hyperspectral images measured from two replicates, 51,173 spectral samples were collected from 1421 colonies. Chemometric preprocessing methods and other operating parameters, such as scatter correction, first derivative, moving average, sample size and number of principal components (PCs), were compared with a classification and regression tree (CART) method, configured as a classification tree and followed by brute-force searching from candidates selected by the CART. The number of PCs, scatter correction and moving average were selected as the most important elements to consider before selecting a set of candidate models. Cross-validation (CV), such as hold out and k-fold CV, was used to validate the prediction performance of candidate models. Serogroups 0111 and 0121 consistently showed over 99% classification accuracy regardless of the classification algorithms. However, the classification accuracies of serogroups 026, 045, 0103 and 0145 showed varying results from 84% up to 100%, depending on which preprocessing treatment and prediction model were adopted. The best overall mean classification accuracy of 95.06% was achieved with PCA-kNN (k=3), six PCs, five-pixel sample size defined around each colony centre, standard normal variate and detrending, first derivative with 11-point gaps and moving average with 11-point gaps. Future studies will focus on automating colony segmentation, further improving detection accuracy of the developed models, expanding the spectral library to include background microflora from ground beef and developing prediction models to detect the target bacteria in the presence of background microflora. C1 [Yoon, Seung-Chul; Windham, William R.; Heitschmidt, Jerry W.; Lawrence, Kurt C.; Park, Bosoon] ARS, Qual & Safety Assessment Res Unit, USA, Dept Agr, Athens, GA USA. [Ladely, Scott R.; Narang, Neelam; Cray, William C.] Food Safety Inspect Serv, Outbreak Sect, Eastern Lab, USA,Dept Agr, Athens, GA USA. RP Yoon, SC (reprint author), ARS, Qual & Safety Assessment Res Unit, USA, Dept Agr, Athens, GA USA. EM seungchul.yoon@ars.usda.gov FU National Institute for Hometown Security FX The authors would like to thank Jerrie Barnett and Peggy Feldner in Quality and Safety Assessment Research Unit in Athens for their assistance for this research. The authors would also like to thank Glenn Tillman at the Food Safety and Inspection Service (FSIS) in Athens for reviewing the manuscript. This project was supported, in part, by a grant from National Institute for Hometown Security. NR 29 TC 12 Z9 12 U1 1 U2 18 PU N I R PUBLICATIONS PI CHICHESTER PA 6 CHARLTON MILL, CHARLTON, CHICHESTER PO18 0HY, WEST SUSSEX, ENGLAND SN 0967-0335 J9 J NEAR INFRARED SPEC JI J. Near Infrared Spectrosc. PY 2013 VL 21 IS 2 BP 81 EP 95 DI 10.1255/jnirs.1043 PG 15 WC Chemistry, Applied; Spectroscopy SC Chemistry; Spectroscopy GA 145OF UT WOS:000319025600001 ER PT J AU Owens, KS Kirwan, JR Lounsbury, JW Levy, JJ Gibson, LW AF Owens, Kimberly S. Kirwan, Jeral R. Lounsbury, John W. Levy, Jacob J. Gibson, Lucy W. TI Personality correlates of self-employed small business owners' success SO WORK-A JOURNAL OF PREVENTION ASSESSMENT & REHABILITATION LA English DT Article DE Entrepreneurship; small business; work satisfaction; business success ID JOB-SATISFACTION; ENVIRONMENT FIT; 5-FACTOR MODEL; WORK DRIVE; ENTREPRENEURS; PERFORMANCE; MANAGERS; METAANALYSIS; MOTIVATIONS; PREDICTORS AB OBJECTIVE: Drawing on prior occupational choice research on entrepreneurs and self-employed business owners, we examined personality predictors of their occupational business success and work satisfaction. PARTICIPANTS AND PROCEDURES: A sample of 147 small business owners completed a web-based assessment of 14work-related personality traits - Adaptability, Autonomy, Competitiveness, Dependability, Emotional Resilience, Goal-Setting, Optimism, Persistence, Risk Tolerance, Self-Promotion, Networking, and Tolerance for Financial Insecurity, Work-Based Locus of Control, and Work Drive - and three self-reported indices of business success - revenue growth, profit growth, and income growth - as well as multiple facets of individual satisfaction. Criterion variables included composite business success and overall satisfaction. RESULTS: Ten traits correlated with business success. The top four personality predictors of success - Goal-Setting, Social Networking, Emotional Resilience, and Work Drive - together accounted for 16% of the variance. Similarly, 12 of 14 personality traits were positively related to overall satisfaction. The top three personality predictors of satisfaction - Optimism, Work-based Locus of Control, and Work Drive - accounted for 29% of the variability in satisfaction. An expectancy analysis revealed that the percent of participants who reported at least a 20% increase in sales and profits the preceding year was 26% versus 54% for individual scoring in the lower and upper third of a personality composite measure. CONCLUSIONS: Results carry implications for future research, and have direct, practical applications for prospective and current entrepreneurs and self-employed owners of small businesses. C1 [Owens, Kimberly S.] USA, Res Inst Behav & Social Sci, Arlington, VA USA. [Kirwan, Jeral R.; Lounsbury, John W.; Levy, Jacob J.] Univ Tennessee, Knoxville, TN 37996 USA. [Gibson, Lucy W.] Resource Associates Inc, Knoxville, TN USA. RP Levy, JJ (reprint author), Univ Tennessee, Dept Psychol, 215G Austin Peay, Knoxville, TN 37996 USA. EM jlevy4@utk.edu NR 79 TC 2 Z9 2 U1 7 U2 42 PU IOS PRESS PI AMSTERDAM PA NIEUWE HEMWEG 6B, 1013 BG AMSTERDAM, NETHERLANDS SN 1051-9815 J9 WORK JI Work PY 2013 VL 45 IS 1 BP 73 EP 85 DI 10.3233/WOR-121536 PG 13 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA 142BA UT WOS:000318769600009 PM 23241705 ER PT B AU Okada, N Cole, JB AF Okada, Naoki Cole, James B. BE Taflove, A Oskooi, A Johnson, SG TI FDTD Modeling of Nondiagonal Anisotropic Metamaterial Cloaks SO ADVANCES IN FDTD COMPUTATIONAL ELECTRODYNAMICS: PHOTONICS AND NANOTECHNOLOGY SE Artech House Antennas and Propagation Series LA English DT Article; Book Chapter ID TIME-DOMAIN METHOD; TRANSFORMATION OPTICS; ELECTROMAGNETIC CLOAKS; COORDINATE TRANSFORMATIONS; INVISIBILITY CLOAKS; DESIGN; BENDS C1 [Okada, Naoki] Univ Tsukuba, Grad Sch Syst & Informat Engn, Dept Comp Sci, Tsukuba, Ibaraki 305, Japan. [Okada, Naoki] JSPS, Tokyo, Japan. [Cole, James B.] Univ Tsukuba, Tsukuba, Ibaraki 305, Japan. [Cole, James B.] USA, Res Lab, Washington, DC USA. RP Okada, N (reprint author), Univ Tsukuba, Grad Sch Syst & Informat Engn, Dept Comp Sci, Tsukuba, Ibaraki 305, Japan. RI Wessels, Bruce/B-7541-2009 NR 56 TC 0 Z9 0 U1 0 U2 0 PU ARTECH HOUSE PI NORWOOD PA 685 CANTON ST, NORWOOD, MA 02062 USA BN 978-1-60807-170-8 J9 ARTECH HSE ANTENN PR PY 2013 BP 255 EP 268 PG 14 WC Mathematics, Interdisciplinary Applications; Optics; Telecommunications SC Mathematics; Optics; Telecommunications GA BET91 UT WOS:000318121700013 ER PT J AU Sokol, JG Cochrane, NA Becker, JJ Gagne, MR AF Sokol, Joseph G. Cochrane, Nikki A. Becker, Jennifer J. Gagne, Michel R. TI Catalytic platinum-initiated cation-olefin reactions with alkene terminating groups SO CHEMICAL COMMUNICATIONS LA English DT Article ID ENANTIOSELECTIVE BIOMIMETIC CYCLIZATION; STABILIZED CARBON NUCLEOPHILES; CHIRAL BRONSTED ACIDS; C BOND FORMATION; DICATIONIC PLATINUM(II); PALLADIUM(II) COMPLEXES; POLYENE CYCLIZATIONS; CHEMISTRY; CASCADE; POLYCYCLIZATION AB A series of phosphine-Pt2+-catalysts is reported, which enable the oxidative cascade cyclization of poly-alkene substrates. When the terminus is appropriately arranged and a catalyst reoxidation mediator is included, several polycyclic all carbon skeletons can be obtained. In one example, a chiral P2Pt+2 catalyst provides up to 79% ee. C1 [Sokol, Joseph G.; Cochrane, Nikki A.; Gagne, Michel R.] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA. [Becker, Jennifer J.] USA, Res Off, Res Triangle Pk, NC 27709 USA. RP Gagne, MR (reprint author), Univ N Carolina, Dept Chem, CB 3290, Chapel Hill, NC 27599 USA. EM mgagne@unc.edu FU NIGMS NIH HHS [R01 GM060578] NR 43 TC 6 Z9 6 U1 2 U2 23 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 1359-7345 J9 CHEM COMMUN JI Chem. Commun. PY 2013 VL 49 IS 44 BP 5046 EP 5048 DI 10.1039/c3cc41699b PG 3 WC Chemistry, Multidisciplinary SC Chemistry GA 139DJ UT WOS:000318561500020 PM 23619982 ER PT J AU Stynoski, P Mondal, P Wotring, E Marsh, C AF Stynoski, Peter Mondal, Paramita Wotring, Erik Marsh, Charles TI Characterization of silica-functionalized carbon nanotubes dispersed in water SO JOURNAL OF NANOPARTICLE RESEARCH LA English DT Article DE Carbon nanotube (CNT); Functionalization; Tetraethyl orthosilicate (TEOS); Dispersion; Point of zero charge; Portland cement ID ZERO CHARGE; POINT; COMPOSITES; SILANE; GEL AB Carbon nanotubes (CNTs) have the potential to enhance the strength, toughness, and multifunctional ability of composite materials. However, suitable dispersion and interfacial bonding remain as key challenges. Composites that are formed by reactions with water, like Portland cement concrete and mortar, pose a special challenge for dispersing the inherently hydrophobic nanotubes. The hydration of Portland cement also offers a specific chemical framework for interfacial bonding. In this study, nanoscale silica functional groups are covalently bonded to CNTs to improve their dispersion in water while providing interfacial bond sites for the proposed matrix material. The bond signatures of treated nanotubes are characterized using Fourier transform infrared spectroscopy. In situ dispersion is characterized using cryogenic transmission electron microscopy and point of zero charge (PZC) measurements. At the nanoscale, inter-particle spacing was greatly increased. A slight increase in the PZC after treatment indicates the importance of steric effects in the dispersion mechanism. Overall, results indicate successful functionalization and dramatically improved dispersion stability in water. C1 [Stynoski, Peter; Mondal, Paramita] Univ Illinois, Dept Civil & Environm Engn, Urbana, IL 61801 USA. [Stynoski, Peter; Wotring, Erik; Marsh, Charles] USA, Construct Engn Res Lab, Champaign, IL 61822 USA. [Marsh, Charles] Univ Illinois, Dept Nucl Plasma & Radiol Engn, Urbana, IL 61801 USA. RP Stynoski, P (reprint author), Univ Illinois, Dept Civil & Environm Engn, 205 N Mathews Ave, Urbana, IL 61801 USA. EM pstynos2@illinois.edu; pmondal@illinois.edu; erik.wotring@usace.army.mil; charles.p.marsh@usace.army.mil FU Section 219 authority of the ERDC; US Department of Energy [DE-FG02-07ER46453, DE-FG02-07ER46471]; US Army Engineer Research and Development Center, Construction Engineering Research Laboratory (ERDC-CERL) FX The authors would like to thank Dr. Charles R. Welch, the US Army Engineer Research and Development Center, Information Technology Laboratory (ERDC-ITL) for his valuable input during informative discussions throughout the experiments. This research is supported in part by the Section 219 authority of the ERDC. Some parts of material characterization was performed at the Frederick Seitz Materials Research Laboratory Central Facilities, University of Illinois, which is partially supported by the US Department of Energy under grants DE-FG02-07ER46453 and DE-FG02-07ER46471. Support was also provided by the Postgraduate Research Participation Program at the US Army Engineer Research and Development Center, Construction Engineering Research Laboratory (ERDC-CERL), administered by the Oak Ridge Institute for Science and Education through an inter-agency agreement between the US Department of Energy and the ERDC-CERL. NR 29 TC 3 Z9 3 U1 1 U2 41 PU SPRINGER PI DORDRECHT PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS SN 1388-0764 J9 J NANOPART RES JI J. Nanopart. Res. PD JAN PY 2013 VL 15 IS 1 AR 1396 DI 10.1007/s11051-012-1396-1 PG 10 WC Chemistry, Multidisciplinary; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Chemistry; Science & Technology - Other Topics; Materials Science GA 138ZC UT WOS:000318550000081 ER PT J AU Cordes, JA Vo, P Lee, JR Geissler, DW Metz, JD Troast, DC Totten, AL AF Cordes, J. A. Vo, P. Lee, J. R. Geissler, D. W. Metz, J. D. Troast, D. C. Totten, A. L. TI Comparison of shock response spectrum for different gun tests SO SHOCK AND VIBRATION LA English DT Article DE Shock response spectrum; accelerations; soft recovery vehicle; Soft Catch Gun; macs 5 charge; setback; set forward; balloting; normal tolerance limit; Excalibur AB The Soft Catch Gun at Picatinny Arsenal is regularly used for component testing. Most shots contain accelerometers which record accelerations as a function of time. Statistics of accelerometer data indicate that the muzzle exit accelerations are, on average, higher than tactical firings. For that reason, Soft Catch Gun tests with unusually high accelerations may not be scored for Lot Acceptance Tests (LAT) by some customers. The 95/50 Normal Tolerance Limit (NTL) is proposed as a means of determining which test results should be scored. This paper presents comparisons of Shock Response Spectra (SRS) used for the 95/50 scoring criteria. The paper also provides a Discussion Section outlining some concerns with scoring LAT results based on test results outside of the proposed 95/50 criteria. C1 [Cordes, J. A.; Lee, J. R.; Geissler, D. W.; Metz, J. D.; Troast, D. C.; Totten, A. L.] US Army ARDEC, Fuze & Precis Armaments Technol RDAR MEF E, Picatinny Arsenal, NJ 07806 USA. [Vo, P.] Raytheon Missile Syst, Tucson, AZ USA. RP Cordes, JA (reprint author), US Army ARDEC, Fuze & Precis Armaments Technol RDAR MEF E, Picatinny Arsenal, NJ 07806 USA. EM jennifer.a.cordes.civ@mail.mil NR 24 TC 0 Z9 1 U1 1 U2 5 PU IOS PRESS PI AMSTERDAM PA NIEUWE HEMWEG 6B, 1013 BG AMSTERDAM, NETHERLANDS SN 1070-9622 J9 SHOCK VIB JI Shock Vib. PY 2013 VL 20 IS 3 BP 481 EP 491 DI 10.3233/SAV-120762 PG 11 WC Acoustics; Engineering, Mechanical; Mechanics SC Acoustics; Engineering; Mechanics GA 142LO UT WOS:000318799100009 ER PT J AU Antonic, V Stojadinovic, A Kester, KE Weina, PJ Brucher, BLDM Protic, M Avital, I Izadjoo, M AF Antonic, Vlado Stojadinovic, Alexander Kester, Kent E. Weina, Peter J. Bruecher, Bjoern L. D. M. Protic, Mladjan Avital, Itzhak Izadjoo, Mina TI Significance of Infectious Agents in Colorectal Cancer Development SO JOURNAL OF CANCER LA English DT Review DE infection; bacteria; virus; infectious agent; colon cancer; colorectal cancer; cancer risk ID HELICOBACTER-PYLORI INFECTION; JC VIRUS-DNA; STREPTOCOCCUS-BOVIS ENDOCARDITIS; GALLOLYTICUS SUBSP GALLOLYTICUS; PYOGENIC LIVER-ABSCESS; T-ANTIGEN EXPRESSION; COLON-CANCER; HUMAN-PAPILLOMAVIRUS; ADENOMATOUS POLYPS; E6 ONCOPROTEIN AB Colorectal cancer (CRC) is a major burden to healthcare systems worldwide accounting for approximately one million of new cancer cases worldwide. Even though, CRC mortality has decreased over the last 20 years, it remains the third most common cause of cancer-related mortality, accounting for approximately 600,000 deaths in 2008 worldwide. A multitude of risk factors have been linked to CRC, including hereditary factors, environmental factors and inflammatory syndromes affecting the gastrointestinal tract. Recently, various pathogens were added to the growing list of risk factors for a number of common epithelial cancers, but despite the multitude of correlative studies, only suggestions remain about the possible relationship between selected viruses and bacteria of interest and the CRC risk. United States military service members are exposed to various risk factors impacting the incidence of cancer development. These exposures are often different from that of many sectors of the civilian population. Thereby, cancer risk identification, screening and early detection are imperative for both the military health care beneficiaries and the population as a whole. In this review, we will focus on several pathogens and their potential roles in development of CRC, highlighting the clinical trials evaluating this correlation and provide our personal opinion about the importance of risk reduction, health promotion and disease prevention for military health care beneficiaries. C1 [Antonic, Vlado; Stojadinovic, Alexander; Kester, Kent E.; Izadjoo, Mina] Combat Wound Initiat Program, Bethesda, MD USA. [Antonic, Vlado; Izadjoo, Mina] Diagnost & Translat Res Ctr, Gaithersburg, MD USA. [Antonic, Vlado; Stojadinovic, Alexander; Izadjoo, Mina] Henry M Jackson Fdn Adv Mil Med, Bethesda, MD USA. [Stojadinovic, Alexander] Walter Reed Natl Mil Med Ctr, Dept Surg, Bethesda, MD USA. [Stojadinovic, Alexander; Protic, Mladjan] US Mil Canc Inst, Bethesda, MD USA. [Stojadinovic, Alexander; Kester, Kent E.; Weina, Peter J.; Avital, Itzhak; Izadjoo, Mina] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA. [Kester, Kent E.; Weina, Peter J.] Walter Reed Army Inst Res, Silver Spring, MD USA. [Bruecher, Bjoern L. D. M.; Avital, Itzhak] Bon Secours Canc Inst, Richmond, VA USA. [Bruecher, Bjoern L. D. M.] Theodor Billroth Acad, Int Consortium Res Excellence, Munich, Germany. [Protic, Mladjan] Theodor Billroth Acad, Int Consortium Res Excellence, INCORE, Munich, Germany. [Protic, Mladjan] Clin Ctr Vojvodina, Clin Abdominal Endocrine & Transplantat Surg, Novi Sad, Serbia. [Protic, Mladjan] Univ Novi Sad, Fac Med, Novi Sad 21000, Serbia. RP Antonic, V (reprint author), Diagnost & Translat Res Ctr, 401 Profess Dr, Gaithersburg, MD USA. EM vantonic@dtrc-hjfresearch.org RI Weina, Peter/A-2120-2011; OI Brucher, Bjorn/0000-0002-3930-6416 FU United States Military Cancer Institute (USMCI); Henry M. Jackson Foundation for the Advancement of Military Medicine FX This work was supported by the United States Military Cancer Institute (USMCI) and the Henry M. Jackson Foundation for the Advancement of Military Medicine. NR 98 TC 20 Z9 23 U1 0 U2 14 PU IVYSPRING INT PUBL PI LAKE HAVEN PA PO BOX 4546, LAKE HAVEN, NSW 2263, AUSTRALIA SN 1837-9664 J9 J CANCER JI J. Cancer PY 2013 VL 4 IS 3 BP 227 EP 240 DI 10.7150/jca.5835 PG 14 WC Oncology SC Oncology GA 135QG UT WOS:000318303000007 PM 23459622 ER PT S AU Goldberg, L Leach, J Chinn, S King, V AF Goldberg, Lew Leach, Jeff Chinn, Stephen King, Vernon BE Zediker, MS TI Speckle characteristics of laser sources for SWIR and NIR active imaging SO HIGH-POWER DIODE LASER TECHNOLOGY AND APPLICATIONS XI SE Proceedings of SPIE LA English DT Proceedings Paper CT Conference on High-Power Diode Laser Technology and Applications XI CY FEB 03-05, 2013 CL San Francisco, CA SP SPIE AB Laser illumination makes it possible to perform high resolution imaging when ambient light level is insufficient to overcome camera noise. The relatively long coherence length of most lasers, however, causes coherent speckle in the camera image plane, which can result in a significant decrease of the image quality and the maximum achievable target identification range. We characterized several types of NIR and SWIR laser diode illumination sources, with emphasis placed on measuring the properties of coherent speckle observed in the camera image plane. Image plane speckle contrast was measured by illuminating the imaged Lambertian surface with single-mode laser, multi-mode laser, wide-stripe laser with two active junctions and broad-band emission, and NIR and SWIR vertical cavity surface emitting laser (VCSEL) arrays. The impact of various imaging system parameters, including pixel size, imaging lens focal length, F-number, and IFOV on the contrast and characteristic size of the speckle intensity distribution were determined. Speckle contrast dependence on the polarization properties of various reflecting surfaces was measured. The reduction of speckle contrast with increasing source spectral width, and increasing size of spatially incoherent VCSEL emitter arrays will be described. We show that a speckle contrast of 5-10% is achievable for a typical long range SWIR imaging system. C1 [Goldberg, Lew; Leach, Jeff; Chinn, Stephen; King, Vernon] USA, RDECOM CERDEC, Night Vis & Elect Sensors Directorate, Washington, DC 20310 USA. RP Goldberg, L (reprint author), USA, RDECOM CERDEC, Night Vis & Elect Sensors Directorate, Washington, DC 20310 USA. EM info@nvl.army.mil NR 7 TC 1 Z9 1 U1 0 U2 5 PU SPIE-INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA SN 0277-786X BN 978-0-8194-9374-3 J9 PROC SPIE PY 2013 VL 8605 AR 860512 DI 10.1117/12.2006269 PG 12 WC Optics; Physics, Applied SC Optics; Physics GA BET48 UT WOS:000318026500033 ER PT J AU Murphey, YL Park, J Kiliaris, L Kuang, ML Abul Masrur, M Phillips, AM Wang, Q AF Murphey, Yi Lu Park, Jungme Kiliaris, Leonidas Kuang, Ming L. Abul Masrur, M. Phillips, Anthony M. Wang, Qing TI Intelligent Hybrid Vehicle Power Control-Part II: Online Intelligent Energy Management SO IEEE TRANSACTIONS ON VEHICULAR TECHNOLOGY LA English DT Article DE Energy optimization; fuel economy; hybrid electric vehicle (HEV) power management; machine learning ID STRATEGY; AGENT AB This is the second paper in a series of two that describe our research in intelligent energy management in a hybrid electric vehicle (HEV). In the first paper, we presented the machine-learning framework ML_EMO_HEV, which was developed for learning the knowledge about energy optimization in an HEV. The framework consists of machine-learning algorithms for predicting driving environments and generating the optimal power split of the HEV system for a given driving environment. In this paper, we present the following three online intelligent energy controllers: 1) IEC_HEV_SISE; 2) IEC_HEV_MISE; and 3) IEC_HEV_MIME. All three online intelligent energy controllers were trained within the machine-learning framework ML_EMO_HEV to generate the best combination of engine power and battery power in real time such that the total fuel consumption over the whole driving cycle is minimized while still meeting the driver's demand and the system constraints, including engine, motor, battery, and generator operation limits. The three online controllers were integrated into the Ford Escape hybrid vehicle model for online performance evaluation. Based on their performances on ten test drive cycles provided by the Powertrain Systems Analysis Toolkit library, we can conclude that the roadway type and traffic congestion level specific machine learning of optimal energy management is effective for in-vehicle energy control. The best controller, IEC_HEV_MISE, trained with the optimal power split generated by the DP optimization algorithm with multiple initial SOC points and single ending point, can provide fuel savings ranging from 5% to 19%. Together, these two papers cover the innovative technologies for modeling power flow, mathematical background of optimization in energy management, and machine-learning algorithms for generating intelligent energy controllers for quasioptimal energy flow in a power-split HEV. C1 [Murphey, Yi Lu; Park, Jungme] Univ Michigan, Dept Elect & Comp Engn, Dearborn, MI 48128 USA. [Kiliaris, Leonidas; Kuang, Ming L.; Phillips, Anthony M.; Wang, Qing] Ford Motor Co, Dearborn, MI 48120 USA. [Abul Masrur, M.] USA, Res Dev & Engn Command RDECOM, TARDEC, Warren, MI 49307 USA. RP Murphey, YL (reprint author), Univ Michigan, Dept Elect & Comp Engn, Dearborn, MI 48128 USA. EM yilu@umich.edu FU State of Michigan; Ford Alliance Program; Institute of Advanced Vehicle Systems, University of Michigan FX This work was supported in part by the State of Michigan through the 21st Jobs Fund, the Ford Alliance Program, and the Institute of Advanced Vehicle Systems, University of Michigan, Dearborn. The review of this paper was coordinated by Dr. K. Deng. NR 22 TC 28 Z9 30 U1 5 U2 57 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0018-9545 J9 IEEE T VEH TECHNOL JI IEEE Trans. Veh. Technol. PD JAN PY 2013 VL 62 IS 1 BP 69 EP 79 DI 10.1109/TVT.2012.2217362 PG 11 WC Engineering, Electrical & Electronic; Telecommunications; Transportation Science & Technology SC Engineering; Telecommunications; Transportation GA 138MZ UT WOS:000318514000007 ER PT J AU Cheng, JRC Huang, XH Shu, S Xu, JC Zhang, CS Zhang, S Zhou, ZY AF Cheng, Jing-Ru C. Huang, Xue-Hai Shu, Shi Xu, Jinchao Zhang, Chen-Song Zhang, Shuo Zhou, Zhiyang TI APPLICATION OF AN ENERGY-MINIMIZING ALGEBRAIC MULTIGRID METHOD FOR SUBSURFACE WATER SIMULATIONS SO INTERNATIONAL JOURNAL OF NUMERICAL ANALYSIS AND MODELING LA English DT Article DE subsurface water simulation; multigrid; algebraic multigrid; energy-minimizing interpolation ID INTERPOLATION; AMGE; AGGREGATION AB Efficient methods for solving linear algebraic equations are crucial to creating fast and accurate numerical simulations in many applications. In this paper, an algebraic multigrid (AMG) method, which combines the classical coarsening scheme by [19] with an energy-minimizing interpolation algorithm by [26], is employed and tested for subsurface water simulations. Based on numerical tests using real field data, our results suggest that the energy-minimizing algebraic multigrid method is efficient and, more importantly, very robust. C1 [Cheng, Jing-Ru C.] USA, Informat Technol Lab, Res Ctr Comp Sci, Engn Res & Dev Ctr, Vicksburg, MS USA. [Huang, Xue-Hai] Wenzhou Univ, Coll Math & Informat Sci, Wenzhou, Peoples R China. [Shu, Shi] Xiangtan Univ, Hunan Key Lab Computat & Simulat Sci & Engn, Xiangtan, Peoples R China. [Xu, Jinchao] Penn State Univ, Dept Math, University Pk, PA 16802 USA. [Zhang, Chen-Song; Zhang, Shuo] Chinese Acad Sci, LSEC & Inst Computat Math & Sci Engn Computat, Beijing, Peoples R China. [Zhou, Zhiyang] Xiangtan Univ, Sch Math & Computat Sci, Xiangtan, Peoples R China. RP Cheng, JRC (reprint author), USA, Informat Technol Lab, Res Ctr Comp Sci, Engn Res & Dev Ctr, Vicksburg, MS USA. RI Huang, Xuehai/F-2934-2013 OI Huang, Xuehai/0000-0003-2966-7426 FU Key Project of Scientific Research Fund of Hunan Provincial Science and Technology Department [2011FJ2011] FX This author was partially supported by the Key Project of Scientific Research Fund of Hunan Provincial Science and Technology Department (Grant No. 2011FJ2011). NR 27 TC 0 Z9 0 U1 0 U2 2 PU ISCI-INST SCIENTIFIC COMPUTING & INFORMATION PI EDMONTON PA PO BOX 60632, UNIV ALBERTA POSTAL OUTLET,, EDMONTON, ALBERTA T6G 2G1, CANADA SN 1705-5105 J9 INT J NUMER ANAL MOD JI Int. J. Numer. Anal. Model. PY 2013 VL 10 IS 2 BP 374 EP 388 PG 15 WC Mathematics, Applied; Mathematics SC Mathematics GA 134TR UT WOS:000318238100006 ER PT J AU Sullivan, KA Elliott, CD Lange, RT Anderson, DS AF Sullivan, Karen A. Elliott, Cameron D. Lange, Rael T. Anderson, Deborah S. TI A Known-Groups Evaluation of the Response Bias Scale in a Neuropsychological Setting SO APPLIED NEUROPSYCHOLOGY-ADULT LA English DT Article DE inadequate effort; malingering; MMPI-2; neuropsychological assessment; Response Bias Scale ID MMPI-2 VALIDITY SCALES; HENRY-HEILBRONNER INDEX; MALINGERED NEUROCOGNITIVE DYSFUNCTION; TRAUMATIC BRAIN-INJURY; OVER-REPORTING SCALES; FAKE BAD SCALE; CLASSIFICATION ACCURACY; MEMORY TEST; RBS; VALIDATION AB We evaluated the Minnesota Multiphasic Personality Inventory-Second Edition (MMPI-2) Response Bias Scale (RBS). Archival data from 83 individuals who were referred for neuropsychological assessment with no formal diagnosis (n=10), following a known or suspected traumatic brain injury (n=36), with a psychiatric diagnosis (n=20), or with a history of both trauma and a psychiatric condition (n=17) were retrieved. The criteria for malingered neurocognitive dysfunction (MNCD) were applied, and two groups of participants were formed: poor effort (n=15) and genuine responders (n=68). Consistent with previous studies, the difference in scores between groups was greatest for the RBS (d=2.44), followed by two established MMPI-2 validity scales, F (d=0.25) and K (d=0.23), and strong significant correlations were found between RBS and F (rs=.48) and RBS and K (r=.41). When MNCD group membership was predicted using logistic regression, the RBS failed to add incrementally to F. In a separate regression to predict group membership, K added significantly to the RBS. Receiver-operating curve analysis revealed a nonsignificant area under the curve statistic, and at the ideal cutoff in this sample of >12, specificity was moderate (.79), sensitivity was low (.47), and positive and negative predictive power values at a 13% base rate were .25 and .91, respectively. Although the results of this study require replication because of a number of limitations, this study has made an important first attempt to report RBS classification accuracy statistics for predicting poor effort at a range of base rates. C1 [Sullivan, Karen A.; Elliott, Cameron D.] Queensland Univ Technol, Sch Psychol & Counseling, Clin Neuropsychol Res Grp, Brisbane, Qld 4059, Australia. [Sullivan, Karen A.] Queensland Univ Technol, Inst Hlth & Biomed Innovat, Brisbane, Qld 4059, Australia. [Lange, Rael T.] Walter Reed Army Med Ctr, Def & Vet Brain Injury Ctr, Washington, DC 20307 USA. [Lange, Rael T.] Univ British Columbia, Vancouver, BC V5Z 1M9, Canada. RP Sullivan, KA (reprint author), Queensland Univ Technol, Sch Psychol & Counseling, Victoria Pk Rd,O Block B Wing Room 523, Brisbane, Qld 4059, Australia. EM karen.sullivan@qut.edu.au RI Anderson, Debra/I-9637-2012 FU School of Psychology and Counseling, Queensland University of Technology FX Funding for this project was provided by the School of Psychology and Counseling, Queensland University of Technology. The research protocol was assessed and approved by the Queensland University of Technology Human Research Ethics Committee (QUT Ref. No. 0900001042) and by occupational workplace health and safety officers. NR 36 TC 4 Z9 4 U1 0 U2 3 PU PSYCHOLOGY PRESS PI HOVE PA 27 CHURCH RD, HOVE BN3 2FA, EAST SUSSEX, ENGLAND SN 0908-4282 J9 APPL NEUROPSYCH-ADUL JI Appl. Neuropsychol.-Adult PD JAN 1 PY 2013 VL 20 IS 1 BP 20 EP 32 DI 10.1080/09084282.2012.670149 PG 13 WC Clinical Neurology; Psychology SC Neurosciences & Neurology; Psychology GA 109PH UT WOS:000316380000004 PM 23373681 ER PT J AU Duarte, FJ Taylor, TS Black, AM Olivares, IE AF Duarte, F. J. Taylor, T. S. Black, A. M. Olivares, I. E. TI Diffractive patterns superimposed over propagating N-slit interferograms SO JOURNAL OF MODERN OPTICS LA English DT Article DE beam expansion; interferometric imaging; N-slit interference; N-slit interferometry; natural fibers; soft measurement ID SECURE INTERFEROMETRIC COMMUNICATIONS; FREE-SPACE AB Transparent, microscopic spider web silk fibers were used to softly intrude into the propagating path of N-slit interferograms. The resulting interferograms, with superimposed diffractive signals, were recorded using digital means and reproduced using N-slit interferometric calculations. We also show, for the first time, very slight and subtle alterations of the propagating interferograms via the soft insertion of spider web silk fibers into the intra-interferometric path. The experiments were performed at an overall intra-interferometric propagation path length of 7.235 m. C1 [Duarte, F. J.] Interferometr Opt, Rochester, NY USA. [Duarte, F. J.] Univ New Mexico, Albuquerque, NM 87131 USA. [Taylor, T. S.; Black, A. M.] USA, Space & Missile Def Command, Ctr Tech, Technol Directorate,Directed Energy Div, Huntsville, AL USA. [Olivares, I. E.] Univ Santiago, Dept Fis, Santiago, Chile. RP Duarte, FJ (reprint author), Interferometr Opt, Rochester, NY USA. EM opticsjournal@gmail.com NR 9 TC 3 Z9 3 U1 1 U2 1 PU TAYLOR & FRANCIS LTD PI ABINGDON PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND SN 0950-0340 J9 J MOD OPTIC JI J. Mod. Opt. PD JAN 1 PY 2013 VL 60 IS 2 BP 136 EP 140 DI 10.1080/09500340.2012.756555 PG 5 WC Optics SC Optics GA 096WV UT WOS:000315436300005 ER PT J AU Pramukkul, P Svenkeson, A Grigolini, P Bologna, M West, B AF Pramukkul, Pensri Svenkeson, Adam Grigolini, Paolo Bologna, Mauro West, Bruce TI Complexity and the Fractional Calculus SO ADVANCES IN MATHEMATICAL PHYSICS LA English DT Article ID ANOMALOUS DIFFUSION; LEVY FLIGHTS; RANDOM-WALKS; CHAOS; ORDER; DYNAMICS; KINETICS; SYSTEMS; MODELS AB We study complex processes whose evolution in time rests on the occurrence of a large and random number of events. The mean time interval between two consecutive critical events is infinite, thereby violating the ergodic condition and activating at the same time a stochastic central limit theorem that supports the hypothesis that the Mittag-Leffler function is a universal property of nature. The time evolution of these complex systems is properly generated by means of fractional differential equations, thus leading to the interpretation of fractional trajectories as the average over many random trajectories each of which satisfies the stochastic central limit theorem and the condition for the Mittag-Leffler universality. C1 [Pramukkul, Pensri; Svenkeson, Adam; Grigolini, Paolo] Univ N Texas, Ctr Nonlinear Sci, Denton, TX 76203 USA. [Bologna, Mauro] Univ Tarapaca, Inst Alta Invest, Arica, Chile. [West, Bruce] USA, Res Off, Informat Sci Directorate, Res Triangle Pk, NC 27709 USA. RP West, B (reprint author), USA, Res Off, Informat Sci Directorate, Res Triangle Pk, NC 27709 USA. EM bruce.j.west.civ@mail.mil FU FONDE-CYT [1110231]; Welch; ARO [B-1577, W911NF1110478] FX M. Bologna acknowledges financial support from FONDE-CYT Project no. 1110231. The authors warmly thank Welch and ARO for the financial support of this work through Grant no. B-1577 and Grant no. W911NF1110478, respectively. NR 39 TC 8 Z9 8 U1 0 U2 11 PU HINDAWI PUBLISHING CORP PI NEW YORK PA 315 MADISON AVE 3RD FLR, STE 3070, NEW YORK, NY 10017 USA SN 1687-9120 EI 1687-9139 J9 ADV MATH PHYS JI Adv. Math. Phys. PY 2013 AR 498789 DI 10.1155/2013/498789 PG 7 WC Physics, Mathematical SC Physics GA 128HC UT WOS:000317758900001 ER PT J AU Eddy, M Grainger, J Holcomb, P AF Eddy, Marianna Grainger, Jonathan Holcomb, Phillip TI REMOVING INDEPENDENT EFFECTS OF THE PRIME ON TARGET ERPS IN MASKED PRIMING PARADIGMS SO JOURNAL OF COGNITIVE NEUROSCIENCE LA English DT Meeting Abstract CT 20th Annual Meeting of the Cognitive-Neuroscience-Society CY APR 13-16, 2013 CL San Francisco, CA SP Cognit Neuroscience Soc C1 [Eddy, Marianna] USA, NSRDEC, Washington, DC USA. [Grainger, Jonathan] CNRS, F-75700 Paris, France. [Grainger, Jonathan] Aix Marseille Univ, Marseille, France. [Eddy, Marianna; Holcomb, Phillip] Tufts Univ, Medford, MA USA. NR 0 TC 0 Z9 0 U1 1 U2 2 PU MIT PRESS PI CAMBRIDGE PA 55 HAYWARD STREET, CAMBRIDGE, MA 02142 USA SN 0898-929X J9 J COGNITIVE NEUROSCI JI J. Cogn. Neurosci. PY 2013 SU S BP 144 EP 144 PG 1 WC Neurosciences; Psychology, Experimental SC Neurosciences & Neurology; Psychology GA 118MV UT WOS:000317030500575 ER PT J AU Ries, A Marathe, A Touryan, J Paul, V AF Ries, Anthony Marathe, Amar Touryan, Jonathan Paul, Victor TI THE EFFECT OF IMAGE FREQUENCY AND SALIENCE ON AVERAGED EVENT-RELATED BRAIN POTENTIALS AND SINGLE-TRIAL CLASSIFICATION SO JOURNAL OF COGNITIVE NEUROSCIENCE LA English DT Meeting Abstract CT 20th Annual Meeting of the Cognitive-Neuroscience-Society CY APR 13-16, 2013 CL San Francisco, CA SP Cognit Neuroscience Soc C1 [Ries, Anthony; Marathe, Amar; Touryan, Jonathan; Paul, Victor] USA, Res Lab, Human Res & Engn Directorate, Aberdeen Proving Ground, MD USA. NR 0 TC 1 Z9 1 U1 0 U2 1 PU MIT PRESS PI CAMBRIDGE PA 55 HAYWARD STREET, CAMBRIDGE, MA 02142 USA SN 0898-929X J9 J COGNITIVE NEUROSCI JI J. Cogn. Neurosci. PY 2013 SU S BP 238 EP 238 PG 1 WC Neurosciences; Psychology, Experimental SC Neurosciences & Neurology; Psychology GA 118MV UT WOS:000317030501307 ER PT J AU Quinton, BT Barnes, PN Varanasi, CV Burke, J Tsao, BH Yost, KJ Mukhopadhyay, SM AF Quinton, Betty T. Barnes, Paul N. Varanasi, Chakrapani V. Burke, Jack Tsao, Bang-Hung Yost, Kevin J. Mukhopadhyay, Sharmila M. TI A Comparative Study of Three Different Chemical Vapor Deposition Techniques of Carbon Nanotube Growth on Diamond Films SO JOURNAL OF NANOMATERIALS LA English DT Article ID RAMAN-SPECTROSCOPY; COMPOSITES; GRAPHENE; SCIENCE; PLASMA AB This paper compares between the methods of growing carbon nanotubes (CNTs) on diamond substrates and evaluates the quality of the CNTs and the interfacial strength. One potential application for these materials is a heat sink/spreader for high-power electronic devices. The CNTs and diamond substrates have a significantly higher specific thermal conductivity than traditional heat sink/spreader materials making them good replacement candidates. Only limited research has been performed on these CNT/diamond structures and their suitability of different growth methods. This study investigates three potential chemical vapor deposition (CVD) techniques for growing CNTs on diamond: thermal CVD (T-CVD), microwave plasma-enhanced CVD (MPE-CVD), and floating catalyst thermal CVD (FCT-CVD). Scanning electron microscopy (SEM) and high-resolution transmission electron microscopy (TEM) were used to analyze the morphology and topology of the CNTs. Raman spectroscopy was used to assess the quality of the CNTs by determining the I-D/I-G. peak intensity ratios. Additionally, the CNT/diamond samples were sonicated for qualitative comparisons of the durability of the CNT forests. T-CVD provided the largest diameter tubes, with catalysts residing mainly at the CNT/diamond interface. The MPE-CVD process yielded non uniform defective CNTs, and FCT-CVD resulted in the smallest diameter CNTs with catalyst particles imbedded throughout the length of the nanotubes. C1 [Quinton, Betty T.; Yost, Kevin J.] USAF, Res Lab, Wright Patterson AFB, OH 45433 USA. [Quinton, Betty T.; Mukhopadhyay, Sharmila M.] Wright State Univ, Dayton, OH 45420 USA. [Barnes, Paul N.] USA, Res Lab, Adelphi, MD 20783 USA. [Varanasi, Chakrapani V.] USA, Res Off, Res Triangle Pk, NC 27709 USA. [Burke, Jack; Tsao, Bang-Hung] UDRI, Dayton, OH 45469 USA. RP Quinton, BT (reprint author), USAF, Res Lab, Wright Patterson AFB, OH 45433 USA. EM bettyyanguic@gmail.com FU Air Force Office of Scientific Research, Air Force Research Laboratory Propulsion Directorate, Wright State University; Ohio Board of Regents FX The authors of the paper would like to thank the funding support of Air Force Office of Scientific Research, Air Force Research Laboratory Propulsion Directorate, Wright State University, and Ohio Board of Regents. The authors would like to acknowledge Dr. Robert Wheeler for his guidance on TEM and EDS. NR 36 TC 2 Z9 2 U1 2 U2 50 PU HINDAWI PUBLISHING CORPORATION PI NEW YORK PA 410 PARK AVENUE, 15TH FLOOR, #287 PMB, NEW YORK, NY 10022 USA SN 1687-4110 J9 J NANOMATER JI J. Nanomater. PY 2013 AR 356259 DI 10.1155/2013/356259 PG 9 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary SC Science & Technology - Other Topics; Materials Science GA 124WX UT WOS:000317500300001 ER PT J AU Jackson, JC Albert, PS Zhang, ZW Simons-Morton, B AF Jackson, John C. Albert, Paul S. Zhang, Zhiwei Simons-Morton, Bruce TI Ordinal latent variable models and their application in the study of newly licensed teenage drivers SO JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS LA English DT Article DE Driving study; Latent class modelling; Monte Carlo expectationmaximization ID LONGITUDINAL BINARY DATA; EM ALGORITHM; MAXIMUM-LIKELIHOOD; BEHAVIOR; TIME AB . In a unique longitudinal study of teen driving, risky driving behaviour and the occurrence of crashes or near crashes are measured prospectively over the first 18 months of licensure. Of scientific interest is relating the two processes and developing a predictor of crashes from previous risky driving behaviour. In this work, we propose two latent class models for relating risky driving behaviour to the occurrence of a crash or near-crash event. The first approach models the binary longitudinal crash or near-crash outcome by using a binary latent variable which depends on risky driving covariates and previous outcomes. A random-effects model introduces heterogeneity among subjects in modelling the mean value of the latent state. The second approach extends the first model to the ordinal case where the latent state is composed of K ordinal classes. Additionally, we discuss an alternative hidden Markov model formulation. Estimation is performed by using the expectationmaximization algorithm and Monte Carlo expectationmaximization. We illustrate the importance of using these latent class modelling approaches through the analysis of the teen driving behaviour. C1 [Jackson, John C.] US Mil Acad, West Point, NY 10996 USA. [Albert, Paul S.; Zhang, Zhiwei; Simons-Morton, Bruce] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Rockville, MD USA. RP Jackson, JC (reprint author), US Mil Acad, Dept Math Sci, Thayer Rd, West Point, NY 10996 USA. EM John.Jackson@usma.edu OI Simons-Morton, Bruce/0000-0003-1099-6617 FU National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development FX We thank the Center for Information Technology, National Institutes of Health, for providing access to the high performance computational capabilities of the Biowulf cluster computing system. The research of Paul S. Albert, Zhiwei Zhang and Bruce Simons-Morton was supported by the intramural research programme of the National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development. We also thank the referees for their thoughtful comments and suggestions which improved our manuscript. NR 19 TC 1 Z9 1 U1 0 U2 2 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0035-9254 J9 J R STAT SOC C-APPL JI J. R. Stat. Soc. Ser. C-Appl. Stat. PY 2013 VL 62 IS 3 BP 435 EP 450 DI 10.1111/j.1467-9876.2012.01065.x PG 16 WC Statistics & Probability SC Mathematics GA 123RW UT WOS:000317409400005 PM 25284899 ER PT J AU Rogers-Bennett, L Hubbard, KE Juhasz, CI AF Rogers-Bennett, Laura Hubbard, Kristin E. Juhasz, Christina I. TI Dramatic declines in red abalone populations after opening a "de facto" marine reserve to fishing: Testing temporal reserves SO BIOLOGICAL CONSERVATION LA English DT Article DE Allee effects; Fishing impacts; Haliotis rufescens; Illegal fishing; Marine Protected Areas; Rotating marine reserves ID HALIOTIS-RUFESCENS; SOUTHERN-CALIFORNIA; FISHERY; CONSERVATION; MANAGEMENT; RECOVERY; BIOLOGY; AREAS AB Red abalone (Haliotis rufescens) were assessed inside and outside a "de facto" reserve before fishing, after 3 and then 6 years of fishing. In just 3 years, there was a 65% decline (p < 0.001) in the subtidal and a 78% decline (p < 0.001) in the intertidal abalone populations. Size frequency distributions differed significantly following fishing and there was a sharp decrease in the potential egg production (>72% decline). Before fishing began, the intertidal density at the reserve was 86% greater (p = 0.001) than at a nearby fished site, however after 3 years of fishing there was no difference (p = 0.764). Abalone fishing report cards revealed a 950% increase in local catch once the reserve site was opened, however after just 1.5 years of fishing, catch declined sharply (59%) compared to the previous year. In 3 years, mean abalone catch per hour declined significantly (p < 0.001) from 7.01 (SD 6.14) to 2.44 (SD 1.98) as did abalone catch/picker from 2.83 (SD 0.47) to 2.38 (SD 0.92, p < 0.01). Estimates of illegal take inside the former reserve were 2.5 times greater than the legal catch. We demonstrate that for areas with high value, slow growing species such as red abalone, temporarily opening reserves may lead to density, size structure and egg production similar to heavily fished areas in just 3 years. These results caution against the use of temporal (rotating) reserves for abalone and emphasize the importance of marine spatial planning. (C) 2012 Elsevier Ltd. All rights reserved. C1 [Rogers-Bennett, Laura; Juhasz, Christina I.] Univ Calif Davis, Bodega Marine Lab, Calif Dept Fish & Game, Bodega Bay, CA 94923 USA. [Hubbard, Kristin E.] Calif Dept Fish & Game, Ft Bragg, CA 94923 USA. RP Rogers-Bennett, L (reprint author), Univ Calif Davis, Bodega Marine Lab, Calif Dept Fish & Game, POB 247, Bodega Bay, CA 94923 USA. EM rogersbennett@ucdavis.edu; khubbard@dfg.ca.gov; cjuhasz@dfg.ca.gov FU California Department of Fish and Game [LR 2012G] FX We thank CDFG GIS Technician, L. McGarvie who generated the Arc View map of Stornetta Ranch. Thank you to the CDFG, UCcontracted, HSU divers lead by P. Buttolph and volunteer divers. The CDFG enforcement staff helped with boat support. We thank D. Rogers for nearest neighbor calculations. A special thank you to the Stornetta family for sharing information about the history of abalone fishing, allowing us access to their property, and for their stewardship of the abalone resource. This work was supported by the California Department of Fish and Game (LR 2012G) to L.R.B. This is a contribution of the Bodega Marine Laboratory, UC Davis. NR 35 TC 5 Z9 5 U1 3 U2 33 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0006-3207 J9 BIOL CONSERV JI Biol. Conserv. PD JAN PY 2013 VL 157 BP 423 EP 431 DI 10.1016/j.biocon.2012.06.023 PG 9 WC Biodiversity Conservation; Ecology; Environmental Sciences SC Biodiversity & Conservation; Environmental Sciences & Ecology GA 113FF UT WOS:000316651200047 ER PT S AU Seda-Sanabria, Y Matheu, E Stephan, R AF Seda-Sanabria, Yazmin Matheu, Enrique Stephan, Robert BE Chavoshian, A Takeuchi, K TI Dealing with disasters: developing an integrated regional resilience strategy SO FLOODS: FROM RISK TO OPPORTUNITY SE IAHS Publication LA English DT Proceedings Paper CT 5th International Conference on Flood Management (ICFM5) CY SEP 27-29, 2011 CL Tokyo, JAPAN SP UNESCO DE flood risk; critical infrastructure; resilience; DSES; dams AB Public-private partnerships can serve as an effective mechanism to collectively strengthen community disaster preparedness and critical infrastructure resilience. This process involves multiple intersecting elements, including Federal, State, regional, local, and private-sector stakeholders, each with unique operating conditions and risks within its own environment. The 2010 Dams Sector Exercise Series (DSES-10) represents an example of the type of public-private effort that can lead to enhanced resilience on a regional scale. This paper discusses the findings and outcomes resulting from the DSES-10 effort, including its capstone Regional Resilience Strategy. The strategy was designed to assist public and private stakeholders in the identification of integrated post-disaster recovery solutions with respect to a catastrophic flood event, prioritization of actions to improve regional disaster resilience, and development of sustainable public-private partnerships to enhance planning and multi-jurisdictional coordination in the context of a wide range of potential threats and hazards. C1 [Seda-Sanabria, Yazmin] US Army Corps Engineers, Crit Infrastruct Protect & Resilience Program, Off Homeland Secur, Directorate Civil Works, Washington, DC 20314 USA. [Matheu, Enrique] US Dept Homeland Secur, Washington, DC 20598 USA. [Stephan, Robert] CRA Inc, Alexandria, VA 22302 USA. RP Seda-Sanabria, Y (reprint author), US Army Corps Engineers, Crit Infrastruct Protect & Resilience Program, Off Homeland Secur, Directorate Civil Works, Washington, DC 20314 USA. EM yazmin.seda-sanabria@usace.army.mil NR 7 TC 0 Z9 0 U1 1 U2 9 PU INT ASSOC HYDROLOGICAL SCIENCES PI WALLINGFORD PA INST OF HYDROLOGY, WALLINGFORD OX10 8BB, ENGLAND SN 0144-7815 BN 978-1-907161-35-3 J9 IAHS-AISH P PY 2013 VL 357 BP 225 EP + PG 3 WC Engineering, Civil; Water Resources SC Engineering; Water Resources GA BEH02 UT WOS:000316508000026 ER PT J AU Riha, GM Kiraly, LN Diggs, BS Cho, SD Fabricant, LJ Flaherty, SF Kuehn, R Underwood, SJ Schreiber, MA AF Riha, Gordon M. Kiraly, Laszlo N. Diggs, Brian S. Cho, S. David Fabricant, Loic J. Flaherty, Stephen F. Kuehn, Reed Underwood, Samantha J. Schreiber, Martin A. TI Management of the Open Abdomen During the Global War on Terror SO JAMA SURGERY LA English DT Article ID DAMAGE CONTROL SURGERY; PENETRATING ABDOMINAL-TRAUMA; OPERATION-IRAQI-FREEDOM; CONTROL RESUSCITATION; CHANGING PATTERNS; THINGS CHANGE; INJURY; COMBAT; STAY AB Objective: To evaluate factors that are predictive of delayed abdominal closure in patients injured during military conflict. Design, Setting, and Patients: Seventy-one patients managed with an open abdomen were identified from records at Landstuhl Regional Medical Center from 2005 and 2006. Follow-up data were available from Walter Reed Army Medical Center. Records were reviewed through all echelons of care. Ordinal logistic regression was used to predict delayed abdominal closure. Results: Patients sustained injury from blunt (n = 2), penetrating (n = 30), and blast (n = 39) mechanisms. The median Injury Severity Score was 25 (interquartile range, 17-34). Abdominal injury was observed in 85% of patients, and 48% underwent a massive transfusion. The median time to transfer to the United States was 5.3 days (interquartile range, 4.3-6.8 days). Abdomens were definitively closed downrange (11%), at Landstuhl Regional Medical Center (33%), or at Walter Reed Army Medical Center (56%). The median time until abdominal closure was 13 days (interquartile range, 4-40 days) in 2005 compared with 4 days (interquartile range, 1-14.5 days) in 2006 (P = .02). The multivariate model identified massive transfusion (odds ratio, 3.9), presence of complications (odds ratio, 5.1), and an injury date in 2005 (odds ratio, 3.4) as independently predictive variables for later abdominal closure. Conclusions: Massive transfusion, occurrence of complications, and earlier injury date were predictive of delayed abdominal closure in casualties managed with an open abdomen. These data suggest an evolving approach to the management of severely injured combat casualties that involves earlier abdominal closure. JAMA Surg. 2013;148(1):59-64. Published online September 17, 2012. doi:10.1001/2013. jamasurg. 4 C1 [Riha, Gordon M.; Kiraly, Laszlo N.; Diggs, Brian S.; Cho, S. David; Fabricant, Loic J.; Underwood, Samantha J.; Schreiber, Martin A.] Oregon Hlth & Sci Univ, Div Trauma Crit Care & Acute Care Surg, Dept Surg, Portland, OR 97239 USA. [Flaherty, Stephen F.] Walter Reed Army Med Ctr, Washington, DC 20307 USA. [Kuehn, Reed] Womack Army Med Ctr, Dept Gen Surg, Ft Bragg, NC USA. RP Riha, GM (reprint author), Oregon Hlth & Sci Univ, Div Trauma Crit Care & Acute Care Surg, 3181 SW Sam Jackson Pk Rd,Mail Code L-611, Portland, OR 97239 USA. EM rihag@ohsu.edu OI Diggs, Brian/0000-0003-3586-3757 NR 24 TC 5 Z9 9 U1 0 U2 4 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60654-0946 USA SN 2168-6254 J9 JAMA SURG JI JAMA Surg. PD JAN PY 2013 VL 148 IS 1 BP 59 EP 64 DI 10.1001/2013.jamasurg.4 PG 6 WC Surgery SC Surgery GA 113NS UT WOS:000316675300013 PM 22987049 ER PT J AU Sturm, M Stuefer, S AF Sturm, Matthew Stuefer, Svetlana TI Wind-blown flux rates derived from drifts at arctic snow fences SO JOURNAL OF GLACIOLOGY LA English DT Article ID ICE-SHEET; SEASONAL SNOW; SEA-ICE; SUBLIMATION; TRANSPORT; COVER; MODEL; THRESHOLD; SNOWDRIFT; SURFACE AB Historically, there has been considerable interest in establishing the relationship between wind-blown snow flux (Q) and wind speed. By monitoring the drift growth at snow fences in Arctic Alaska during three winters, we computed Q for 36 distinct transport events. Each fence was instrumented with depth sounders to measure deposition rates. The majority of events (31) occurred between November and February, despite winter extending from October to June. On average, five substantial snow deposition events (SDEs) occurred at each fence per winter. The mean flux during SDEs was 0.16, 0.19 and 0.29 kg s(-1) m(-1) at Barrow, Imnavait Creek and Franklin Bluffs, respectively, the differences in Q explained by the different wind regimes at the three sites. To place these flux measurements in perspective, we reviewed all previous experimental values of Q, with special attention to height and time over which the fluxes were measured. The new data help fill a range of wind speeds (12-18 m s(-1)) where prior results have been sparse. Combined, the full data define a diffuse cloud best represented by upper and lower bounding equations Q(U) = 1.3 x 10(-3)W(2.5) and Q(L) =3.3 x10(-9)W(6.5), where W is wind speed (>5 m s(-1)). We suggest that these bounds, rather than a single equation, provide the best way to estimate snow fluxes. C1 [Sturm, Matthew] USA, Cold Reg Res & Engn Lab, Ft Wainwright, AK USA. [Stuefer, Svetlana] Univ Alaska Fairbanks, Water & Environm Res Ctr, Dept Civil & Environm Engn, Fairbanks, AK USA. RP Sturm, M (reprint author), USA, Cold Reg Res & Engn Lab, Ft Wainwright, AK USA. EM matthew.sturm@usace.army.mil OI Stuefer, Svetlana/0000-0003-0740-8335 FU US National Science Foundation-Office of Polar Programs (SnowNET); US Department of Energy, National Energy Technology Laboratory [DE-NT0005684] FX Dozens of people helped to collect the data reported here. In particular, we thank Art Gelvin, Chris Hiemstra, Stephanie Saari, Ken Irving, Joel Bailey, Glen Liston, Simon Filhol, Ken Tape, Tom Douglas, Andrew Slater and Mark Serreze. Carl Benson was the first to recognize how snow fences could be used to understand blowing-snow fluxes and he retains a keen interest in the subject. Stephen Dery, Ruzica Dadic and an anonymous referee provided valuable comments in review. Logistical support for work in Barrow was provided by the Barrow Arctic Science Consortium and the Ukpeagvik Inupiat Corporation (Umiaq). Logistical support at Imnavait and Franklin Bluffs was provided by Toolik Lake Field Station and CH2M HILL Polar Services. The work was supported by a grant from the US National Science Foundation-Office of Polar Programs (SnowNET) and the US Department of Energy, National Energy Technology Laboratory, award No. DE-NT0005684. The paper is dedicated to the memory of Ron Tabler, who did more than anyone else to understand drifting snow and snow fences. NR 61 TC 7 Z9 7 U1 0 U2 13 PU INT GLACIOL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE CB2 1ER, ENGLAND SN 0022-1430 J9 J GLACIOL JI J. Glaciol. PY 2013 VL 59 IS 213 BP 21 EP 34 DI 10.3189/2013JoG12J110 PG 14 WC Geography, Physical; Geosciences, Multidisciplinary SC Physical Geography; Geology GA 109MU UT WOS:000316373500003 ER PT J AU Pollack, KM Yee, N Canham-Chervak, M Rossen, L Bachynski, KE Baker, SP AF Pollack, Keshia M. Yee, Nathan Canham-Chervak, Michelle Rossen, Lauren Bachynski, Kathleen E. Baker, Susan P. TI Narrative text analysis to identify technologies to prevent motor vehicle crashes: Examples from military vehicles SO JOURNAL OF SAFETY RESEARCH LA English DT Article; Proceedings Paper CT 5th National Occupational Injury Research Symposium (NOIRS) CY OCT, 2011 CL Natl Inst Occupat Safety & Hlth (NIOSH), Morgantown, WV SP Natl Safety Council, Liberty Mutual Res Inst Safety HO Natl Inst Occupat Safety & Hlth (NIOSH) DE Narrative text analysis; Motor vehicle; Technology; US Army; Occupational injury ID INJURIES AB Introduction: The purpose of this research is to describe the leading circumstances of military vehicle crashes to guide prioritization and implementation of crash avoidance and/or warning technologies. Methods: A descriptive study using narrative text analysis on 3,944 military vehicle crash narratives. Crash data on drivers, from 2001 to 2006, were assembled from the U.S. Army Combat Readiness/Safety Center. Reviewers collected information on the circumstances of crashes and determined if vehicle technology could have prevented the crash. Results: Nearly 98% of the crashes were nonfatal; 63% occurred in the U.S. and 24% in Iraq. Among crash events where the direction of the impact was recorded, 32% were to the front of the vehicle and 16% involved a vehicle being rear-ended. Rollovers were mentioned in 20% of the narratives. Technology was determined to have the potential to prevent 26% of the crashes, with the forward collision warning system, rear end collision avoidance, emergency brake assistance, and rollover stability control system likely to have the greatest impacts. Conclusions: Some technologies available for civilian vehicles may prevent certain military crash circumstances. Impact on Industry: The results of this research are significant in light of ongoing global military operations that rely on military vehicles. Improving the preventive technology featured on military vehicles may be an effective strategy to reduce the occurrence of military crashes. (C) 2013 National Safety Council and Elsevier Ltd. All rights reserved. C1 [Pollack, Keshia M.; Baker, Susan P.] Johns Hopkins Ctr Injury Res & Policy, Johns Hopkins Bloomberg Sch Publ Hlth, Dept Hlth Policy & Management, Baltimore, MD 21205 USA. [Yee, Nathan] Univ Calif, Sch Med, Berkeley, CA USA. [Canham-Chervak, Michelle] USA, Injury Prevent Program, Aberdeen Proving Ground, MD 21010 USA. [Rossen, Lauren] Ctr Dis Control & Prevent, Natl Ctr Hlth Stat, Hyattsville, MD 20782 USA. [Bachynski, Kathleen E.] Columbia Univ, Mailman Sch Publ Hlth, Dept Sociomed Sci, New York, NY 10032 USA. RP Pollack, KM (reprint author), Johns Hopkins Univ, 624 N Broadway,Room 557, Baltimore, MD 21205 USA. EM kpollack@jhsph.edu FU NCIPC CDC HHS [5R49CE001507] NR 18 TC 3 Z9 3 U1 0 U2 9 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0022-4375 J9 J SAFETY RES JI J. Saf. Res. PY 2013 VL 44 IS 1 SI SI BP 45 EP 49 DI 10.1016/j.jsr.2012.10.013 PG 5 WC Ergonomics; Public, Environmental & Occupational Health; Social Sciences, Interdisciplinary; Transportation SC Engineering; Public, Environmental & Occupational Health; Social Sciences - Other Topics; Transportation GA 110ER UT WOS:000316425900008 PM 23398704 ER PT J AU Hannah, ST Jennings, PL AF Hannah, Sean T. Jennings, Peter L. TI Leader Ethos and Big-C Character SO ORGANIZATIONAL DYNAMICS LA English DT Article C1 [Hannah, Sean T.] Wake Forest Univ, Sch Business, Winston Salem, NC 27109 USA. [Jennings, Peter L.] US Mil Acad, CAPE, West Point, NY USA. RP Hannah, ST (reprint author), Wake Forest Univ, Sch Business, Winston Salem, NC 27109 USA. EM hannahst@wfu.edu; Peter.jennings@usma.edu NR 23 TC 4 Z9 4 U1 1 U2 4 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 0090-2616 J9 ORGAN DYN JI Organ. Dyn. PD JAN-MAR PY 2013 VL 42 IS 1 SI SI BP 8 EP 16 DI 10.1016/j.orgdyn.2012.12.002 PG 9 WC Business; Psychology, Applied; Management SC Business & Economics; Psychology GA 116YX UT WOS:000316920400002 ER PT J AU Bedno, SA Cowan, DN Urban, N Niebuhr, DW AF Bedno, Sheryl A. Cowan, David N. Urban, Nadia Niebuhr, David W. TI Effect of pre-accession physical fitness on training injuries among US Army recruits SO WORK-A JOURNAL OF PREVENTION ASSESSMENT & REHABILITATION LA English DT Article DE Musculoskeletal injury; military; healthcare utilization; step test ID LIMITED-DUTY DAYS; RISK-FACTORS; MUSCULOSKELETAL INJURIES; STEP TEST; OXYGEN-UPTAKE; MILITARY; PREVENTION; SURVEILLANCE; POPULATIONS; ATTRITION AB OBJECTIVE: To evaluate the association of pre-accession physical fitness, as measured by a five-minute step test, with incidence of overuse injuries and outpatient healthcare utilization among male United States (US) Army recruits. PARTICIPANTS: US Army male trainees who met weight standards and took a pre-accession fitness test. METHODS: In this prospective cohort study, incidence and outpatient healthcare visits for overuse injuries during the first 90 days of military service were compared between recruits who failed the pre-accession step test with those who passed. RESULTS: The hazard rate ratio for injury among recruits who failed the fitness test compared to those who passed the test was 1.31 (95% C. I = 1.20-1.44). Among the subset of recruits with at least one medical encounter for an overuse injury, the utilization rate ratio for subjects who failed the fitness test versus those who passed was 1.15 (95% C. I = 1.09-1.22). Other factors associated with increased risk of injury or healthcare utilization include age, body mass index, and smoking history. CONCLUSIONS: Risk of injury and utilization were associated with fitness test results. These findings may have implications for military accession and training policy as well as for other physically demanding training programs such as police, fire fighters and athletes. C1 [Bedno, Sheryl A.] Dwight D Eisenhower Army Med Ctr, Occupat Hlth Serv, Ft Gordon, GA 30905 USA. [Cowan, David N.; Urban, Nadia; Niebuhr, David W.] Walter Reed Army Inst Res, Div Prevent Med, Silver Spring, MD USA. [Cowan, David N.; Urban, Nadia] Allied Technol Grp, Rockville, MD USA. RP Bedno, SA (reprint author), Dwight D Eisenhower Army Med Ctr, Occupat Hlth Serv, 300 East Hosp Rd, Ft Gordon, GA 30905 USA. EM sheryl.ann.bedno@us.army.mil NR 34 TC 10 Z9 10 U1 1 U2 7 PU IOS PRESS PI AMSTERDAM PA NIEUWE HEMWEG 6B, 1013 BG AMSTERDAM, NETHERLANDS SN 1051-9815 J9 WORK JI Work PY 2013 VL 44 IS 4 BP 509 EP 515 DI 10.3233/WOR-2012-1355 PG 7 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA 116AA UT WOS:000316852800014 PM 22927579 ER PT J AU Krakauer, T AF Krakauer, Teresa TI DETERMINATION OF C5a IN MURINE MODELS OF STAPHYLOCOCCAL ENTEROTOXIN BINDUCED TOXIC SHOCK SO JOURNAL OF IMMUNOASSAY & IMMUNOCHEMISTRY LA English DT Article DE C5a; LPS; murine models; SEB; toxic shock ID CLASS-II MOLECULES; LETHAL SHOCK; BACTERIAL SUPERANTIGENS; T-CELLS; ACTIVATION; COMPLEMENT; RELEASE; DISEASE; SEPSIS AB Robust host innate immune response to staphylococcal enterotoxin B (SEB) and structurally related superantigens causes toxic shock and various autoimmune diseases. While proinflammatory cytokines are known for mediating SEB-induced toxicity, the role of complement C5a in SEB-mediated shock is less well-understood. An ELISA was developed to measure the complement activation product, C5a, in different murine models of toxic shock. This assay provides easy, quantifiable data for complement activation and its role in various SEB-induced toxic shock models. C1 [Krakauer, Teresa] USA, Med Res Inst Infect Dis, Integrated Toxicol Div, Ft Detrick, MD 21702 USA. RP Krakauer, T (reprint author), USAMRIID, Dept Immunol & Mol Biol, Bldg 1425, Frederick, MD 21702 USA. EM teresa.krakauer@us.army.mil NR 28 TC 0 Z9 0 U1 0 U2 0 PU TAYLOR & FRANCIS INC PI PHILADELPHIA PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA SN 1532-1819 J9 J IMMUNOASS IMMUNOCH JI J. Immunoass. Immunoch. PD JAN 1 PY 2013 VL 34 IS 1 BP 30 EP 38 DI 10.1080/15321819.2012.668150 PG 9 WC Biochemical Research Methods; Immunology; Medical Laboratory Technology SC Biochemistry & Molecular Biology; Immunology; Medical Laboratory Technology GA 105HH UT WOS:000316056800003 PM 23323979 ER PT J AU Rogers, J Costello, M Cooper, G AF Rogers, Jonathan Costello, Mark Cooper, Gene TI Design Considerations for Stability of Liquid Payload Projectiles SO JOURNAL OF SPACECRAFT AND ROCKETS LA English DT Article ID SPINNING PROJECTILE; FILLED PROJECTILES; SPACECRAFT; FLIGHT; DYNAMICS; MOTION; TANKS AB It is well known that projectiles equipped with liquid payloads experience large destabilizing moments induced by internal motion of the fluid. For some configurations, these moments may lead to catastrophic flight instabilities. This paper explores how payload geometry, fluid spin-up rate, and the magnitude of launch perturbations affect the flight trajectories of projectiles with a liquid payload, including projectile instability. A dynamic simulation model is used in which a projectile rigid-body dynamics representation incorporates liquid moments generated from linearized Navier-Stokes predictions. A novel feature of this simulation is its use of linear filtering within the model, which determines fast- and slow-mode angle-of-attack contributions at each time step to be used in computation of liquid moments. Example cases and Monte Carlo simulations demonstrate how design factors and launch perturbations affect the projectile's tendency to exhibit flight instability. The paper concludes with a summary of advantageous design characteristics that are likely to mitigate the effects of destabilizing liquid moments. C1 [Rogers, Jonathan] Texas A&M Univ, Dept Aerosp Engn, College Stn, TX 77843 USA. [Costello, Mark] Georgia Inst Technol, Sch Aerosp Engn, Atlanta, GA 30332 USA. [Cooper, Gene] USA, Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. RP Rogers, J (reprint author), Texas A&M Univ, Dept Aerosp Engn, College Stn, TX 77843 USA. NR 30 TC 1 Z9 2 U1 0 U2 3 PU AMER INST AERONAUT ASTRONAUT PI RESTON PA 1801 ALEXANDER BELL DRIVE, STE 500, RESTON, VA 22091-4344 USA SN 0022-4650 J9 J SPACECRAFT ROCKETS JI J. Spacecr. Rockets PD JAN-FEB PY 2013 VL 50 IS 1 BP 169 EP 178 DI 10.2514/1.A32292 PG 10 WC Engineering, Aerospace SC Engineering GA 102HN UT WOS:000315835800013 ER PT J AU Acharya, S Alvarado, J Banerjee, D Billups, WE Chen, G Cola, BA Cross, W Duke, E Graham, S He, H Hong, H Jin, S Karna, S Li, C Li, CH Li, J Peterson, GP Puszynski, JA Routbort, J Shan, J Shin, D Smirnova, A Smith, P Wang, X Waynick, A White, R Yan, X Yu, W AF Acharya, S. Alvarado, J. Banerjee, D. Billups, W. E. Chen, G. Cola, B. A. Cross, W. Duke, E. Graham, S., Jr. He, H. Hong, H. Jin, S. Karna, S. Li, C. Li, C. H. Li, J. Peterson, G. P. Puszynski, J. A. Routbort, J. Shan, J. Shin, D. Smirnova, A. Smith, P. Wang, X. Waynick, A. White, R. Yan, X. Yu, W. TI Report on Carbon Nano Material Workshop: Challenges and Opportunities SO NANOSCALE AND MICROSCALE THERMOPHYSICAL ENGINEERING LA English DT Article DE carbon nanomaterial; thermal property; nanofluids; carbon nanotube; graphene AB The objective of this workshop was to focus on new directions in carbon nanomaterial research, with a particular focus on new frontiers in nanotube alignment and applications of nanofluids. The first Carbon Nano Material Workshop was held at the Radisson Hotel, Rapid City, South Dakota, from October 30 to November 1, 2011, and was organized by Dr. G. P. Bud Peterson, Georgia Institute of Technology, and Dr. Haiping Hong, South Dakota School of Mines and Technology. More than 70 people from various government agencies, national labs, universities, and industries attended the workshop. The workshop agenda follows. The workshop included keynote plenary sessions and invited and contributed sessions, as well as a dedicated poster session of selected presentations assembled from an open call for papers. C1 [Acharya, S.] Natl Sci Fdn, Arlington, VA USA. [Alvarado, J.; Banerjee, D.] Texas A&M Univ, Dept Mech Engn, College Stn, TX 77843 USA. [Billups, W. E.] Rice Univ, Dept Chem, Houston, TX USA. [Chen, G.] MIT, Dept Mech Engn, Cambridge, MA 02139 USA. [Cola, B. A.; Graham, S., Jr.; Peterson, G. P.] Georgia Inst Technol, George W Woodruff Sch Mech Engn, Atlanta, GA 30332 USA. [Cross, W.; Hong, H.] South Dakota Sch Mines & Technol, Dept Mat & Met Engn, Rapid City, SD 57701 USA. [Duke, E.] South Dakota Sch Mines & Technol, South Dakota NASA EPSCoR, Rapid City, SD 57701 USA. [He, H.] Rutgers State Univ, Dept Chem, Newark, NJ 07102 USA. [Jin, S.] Univ Calif San Diego, Dept Mech & Aerosp Engn, San Diego, CA 92103 USA. [Karna, S.; Smith, P.] USA, Res Lab, Aberdeen Proving Ground, MD USA. [Li, C.] Univ S Carolina, Dept Mech Engn, Columbia, SC 29208 USA. [Li, C. H.] Villanova Univ, Dept Mech Engn, Villanova, PA 19085 USA. [Li, J.] NASA, Ctr Nanotechnol, Ames Res Lab, Moffett Field, CA USA. [Puszynski, J. A.] South Dakota Sch Mines & Technol, Dept Chem & Biol Engn, Rapid City, SD 57701 USA. [Routbort, J.; Yu, W.] Argonne Natl Lab, Div Energy Syst, Argonne, IL 60439 USA. [Shan, J.] Rutgers State Univ, Dept Mech & Aerosp Engn, Piscataway, NJ 08855 USA. [Shin, D.] Univ Texas Arlington, Dept Mech & Aerosp Engn, Arlington, TX 76019 USA. [Smirnova, A.] South Dakota Sch Mines & Technol, Dept Chem, Rapid City, SD 57701 USA. [Wang, X.] Iowa State Univ, Dept Mech Engn, Ames, IA USA. [Waynick, A.] NCH Corp, R&D Div, Irving, TX USA. [White, R.] South Dakota Sch Mines & Technol, Off Res, Rapid City, SD 57701 USA. [Yan, X.] S Dakota State Univ, Dept Elect Engn & Comp Sci, Brookings, SD 57007 USA. RP Hong, H (reprint author), South Dakota Sch Mines & Technol, Dept Mat & Met Engn, 501 St Joseph St, Rapid City, SD 57701 USA. EM Haiping.Hong@sdsmt.edu RI Cola, Baratunde/N-1903-2013; YAN, Xingzhong/B-5074-2011; Chen, Gang/J-1325-2014; Li, Calvin Hong/B-6905-2009; OI Cola, Baratunde/0000-0003-1268-9573; Chen, Gang/0000-0002-3968-8530; Alvarado, Jorge/0000-0002-4059-6588 FU South Dakota School of Mines and Technology; Georgia Institute of Technology; U.S. Army Research Laboratory; South Dakota NASA Experimental Program to Stimulate Competitive Research (EPSCoR); National Science Foundation FX This workshop was financially supported by the South Dakota School of Mines and Technology, the Georgia Institute of Technology, the U.S. Army Research Laboratory, the South Dakota NASA Experimental Program to Stimulate Competitive Research (EPSCoR), and the National Science Foundation. NR 28 TC 3 Z9 3 U1 0 U2 16 PU TAYLOR & FRANCIS INC PI PHILADELPHIA PA 530 WALNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA SN 1556-7265 EI 1556-7273 J9 NANOSC MICROSC THERM JI Nanoscale Microscale Thermophys. Eng. PD JAN 1 PY 2013 VL 17 IS 1 BP 10 EP 24 DI 10.1080/15567265.2012.745912 PG 15 WC Thermodynamics; Engineering, Mechanical; Nanoscience & Nanotechnology; Materials Science, Characterization & Testing; Physics, Applied SC Thermodynamics; Engineering; Science & Technology - Other Topics; Materials Science; Physics GA 105IA UT WOS:000316059000002 ER PT S AU Taylor, HA Brunye, TT AF Taylor, Holly A. Brunye, Tad T. BE Ross, BH TI The Cognition of Spatial Cognition: Domain-General within Domain-specific SO PSYCHOLOGY OF LEARNING AND MOTIVATION, VOL 58 SE Psychology of Learning and Motivation LA English DT Article; Book Chapter ID VISUOSPATIAL WORKING-MEMORY; OLDER-ADULTS; MENTAL REPRESENTATIONS; NARRATIVE COMPREHENSION; INATTENTIONAL BLINDNESS; LANGUAGE COMPREHENSION; VISUAL INFORMATION; EMBODIED COGNITION; PERSPECTIVE-TAKING; CUE UTILIZATION AB Few would argue against the position that spatial cognition involves cognition. Much of spatial cognition research has focused on illuminating the domain-general processes (e.g. attention, memory, or representation) active in this domain-specific field. In this chapter, we suggest that researchers view this domain-general to domain-specific relationship in the opposite direction. In other words, we review spatial cognition research within the context of its utility for understanding domain-general processes. For a cognitive process to be domain-general, it should be evident across a wide variety of domain-specific tasks, including verbal and spatial ones. Yet, the majority of data supporting domain-general models comes from verbal tasks, such as list learning. Thus, we suggest that considering spatial cognition tasks and findings along with those from other domains would enhance our understanding of truly domain-general processing. C1 [Taylor, Holly A.; Brunye, Tad T.] Tufts Univ, Dept Psychol, Medford, MA 02155 USA. [Brunye, Tad T.] USA, Natick Soldier Res Dev & Engn Ctr, Natick, MA 01760 USA. RP Taylor, HA (reprint author), Tufts Univ, Dept Psychol, Medford, MA 02155 USA. EM holly.taylor@tufts.edu NR 187 TC 2 Z9 2 U1 6 U2 18 PU ELSEVIER ACADEMIC PRESS INC PI SAN DIEGO PA 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 USA SN 0079-7421 BN 978-0-12-407237-4 J9 PSYCHOL LEARN MOTIV JI Psychol. Learn. Motiv. PY 2013 VL 58 BP 77 EP 116 DI 10.1016/B978-0-12-407237-4.00003-7 PG 40 WC Psychology, Experimental SC Psychology GA BDY04 UT WOS:000315604100003 ER PT J AU Rice, V AF Rice, Valerie TI An Ergonomic Focus on Children, Youth, and Education SO WORK-A JOURNAL OF PREVENTION ASSESSMENT & REHABILITATION LA English DT Editorial Material C1 USA, Res Lab HRED AMEDD, Field Element, STE R, San Antonio, TX 78234 USA. RP Rice, V (reprint author), USA, Res Lab HRED AMEDD, Field Element, STE R, 2377 Greeley Rd, San Antonio, TX 78234 USA. EM valerie.rice1@us.army.mil NR 6 TC 0 Z9 0 U1 0 U2 0 PU IOS PRESS PI AMSTERDAM PA NIEUWE HEMWEG 6B, 1013 BG AMSTERDAM, NETHERLANDS SN 1051-9815 J9 WORK JI Work PY 2013 VL 44 SU 1 SI SI BP S1 EP S3 DI 10.3233/WOR-2012-01587 PG 3 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA 111LV UT WOS:000316523700001 PM 23396383 ER PT J AU Rice, VJB Butler, J Marra, D AF Rice, Valerie J. B. Butler, Jenny Marra, Diane TI The relationship between symptoms of Attention Deficit and Hyperactivity Disorder and Oppositional Defiant Disorder with soldier performance during training SO WORK-A JOURNAL OF PREVENTION ASSESSMENT & REHABILITATION LA English DT Article DE Attention; ADHD; ODD; military; performance ID DEFICIT/HYPERACTIVITY DISORDER; BURN INJURIES; CHILDREN; ADHD; ADOLESCENTS; ADULTS; RISK; AGE; COMORBIDITY; PERSISTENCE AB OBJECTIVE: During interviews with Health Care Specialist military cadre, instructors voiced concern that symptoms associated with attention deficit and hyperactivity disorder (SoADHD) and oppositional defiant disorder (SoODD) were interfering with soldiers' ability to complete training. The purpose of this research was to examine the relationship between SoADHD and SoODD with soldiers' grade point average (GPA), Army Physical Fitness Test (APFT) scores, and musculoskeletal injuries during Health Care Specialist (HCS) Advanced Individual Training (AIT). METHOD: Participants included 122 soldiers attending HCS training. Participants completed a demographic survey and Barkley and Murphy's ADHD and ODD self-report symptom surveys. Their ADHD and ODD self-report scores were correlated with course performance metrics at the conclusion of their 16 weeks of training. RESULTS: Pearson Correlation Coefficients revealed a significant negative relationship between ratings on the Oppositional Defiant Disorder scale with soldiers' GPA (p < 0.05), however the relationship was weak accounting for 4% of the variance. No significant findings were noted between SoADHD and GPA, nor were significant relationships found between SoADHD or SoODD with APFT scores or musculoskeletal injuries. CONCLUSION: Symptoms associated with ADHD and ODD had little impact on the academic and physical performance of soldiers attending HCS training. Implications and future research are explored, in this article. C1 [Rice, Valerie J. B.; Butler, Jenny; Marra, Diane] USA, Res Lab HRED AMEDD Field Element, San Antonio, TX 78234 USA. RP Rice, VJB (reprint author), USA, Res Lab HRED AMEDD Field Element, 2377 Greeley Rd STE R, San Antonio, TX 78234 USA. EM valerie.rice1@us.army.mil NR 41 TC 1 Z9 1 U1 0 U2 4 PU IOS PRESS PI AMSTERDAM PA NIEUWE HEMWEG 6B, 1013 BG AMSTERDAM, NETHERLANDS SN 1051-9815 J9 WORK JI Work PY 2013 VL 44 SU 1 SI SI BP S105 EP S114 DI 10.3233/WOR-121544 PG 10 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA 111LV UT WOS:000316523700010 PM 23241709 ER PT J AU McLay, RN Loeffler, GH Wynn, GH AF McLay, Robert N. Loeffler, George H. Wynn, Gary H. TI Research Methodology for the Study of Complementary and Alternative Medicine in the Treatment of Military PTSD SO PSYCHIATRIC ANNALS LA English DT Article ID POSTTRAUMATIC-STRESS-DISORDER; MEMORY; WATER C1 [McLay, Robert N.] USN, San Diego Med Ctr, Directorate Mental Hlth, Dept Mental Hlth, San Diego, CA 92122 USA. [McLay, Robert N.; Loeffler, George H.] USN, San Diego Med Ctr, Directorate Mental Hlth, San Diego, CA 92122 USA. [Wynn, Gary H.] Walter Reed Army Inst Res, Ctr Mil Psychiat & Neurosci, Silver Spring, MD USA. RP McLay, RN (reprint author), USN, San Diego Med Ctr, Directorate Mental Hlth, 4370 La Jolla Village Dr,Suite 400, San Diego, CA 92122 USA. EM robert.mcclay@med.navy.mil NR 36 TC 1 Z9 1 U1 5 U2 13 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 USA SN 0048-5713 J9 PSYCHIAT ANN JI Psychiatr. Ann. PD JAN PY 2013 VL 43 IS 1 BP 38 EP 43 DI 10.3928/00485713-20130109-09 PG 6 WC Psychiatry SC Psychiatry GA 099OB UT WOS:000315630000009 ER PT J AU Lovering, ME Proctor, SP Heaton, KJ AF Lovering, Meghan E. Proctor, Susan P. Heaton, Kristin J. TI A retrospective study of anxiety disorder diagnoses in the military from 2000 to 2009 SO JOURNAL OF ANXIETY DISORDERS LA English DT Article DE Anxiety disorders; Military; PTSD; Rates; DMED ID NATIONAL-COMORBIDITY-SURVEY; POSTTRAUMATIC-STRESS-DISORDER; MENTAL-HEALTH PROBLEMS; DSM-IV DISORDERS; SURVEY REPLICATION; US MILITARY; COMBAT; PREVALENCE; DEPLOYMENT; WOMEN AB The objective of this study was to describe trends in the diagnostic rates for anxiety disorders (ADs) types in the U.S. military from 2000 to 2009. Data for the numbers of diagnosed cases for the first documented occurrence of ADs during ambulatory visits while serving in the military were obtained from the Defense Medical Epidemiology Database for all active duty service members and examined across branch of service and by gender. Results indicate that Anxiety Not Otherwise Specified (ANOS) was the most frequently diagnosed AD type in each of the 10 years between 2000 and 2009, with an average rate of 0.8 per 100 service members for first service occurrence, followed by PTSD at a rate of 0.5 out of every 100. Starting in 2002, the yearly first occurrence rates of ANDS and PTSD were significantly higher (p < 0.001) compared to each proceeding year, with the same pattern present among males and females separately. The majority of first occurrence AD diagnoses were diagnosed in the Army (47% of Anxiety NOS and 60% of PTSD cases) compared to the other service branches (i.e., Navy, Air Force, and Marines). (C) 2012 Elsevier Ltd. All rights reserved. C1 [Lovering, Meghan E.; Proctor, Susan P.; Heaton, Kristin J.] USA, Environm Med Res Inst, Natick, MA 01760 USA. [Proctor, Susan P.; Heaton, Kristin J.] Boston Univ, Sch Publ Hlth, Dept Environm Hlth, Boston, MA USA. [Proctor, Susan P.] VA Boston Healthcare Syst, Res Serv, Boston, MA USA. RP Lovering, ME (reprint author), USA, Environm Med Res Inst, 15 Kansas St,Bldg 42, Natick, MA 01760 USA. EM meghan.lovering@us.army.mil RI Heaton, Kristin/E-3660-2013 NR 33 TC 1 Z9 1 U1 1 U2 15 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0887-6185 J9 J ANXIETY DISORD JI J. Anxiety Disord. PD JAN PY 2013 VL 27 IS 1 BP 25 EP 32 DI 10.1016/j.janxdis.2012.10.003 PG 8 WC Psychology, Clinical; Psychiatry SC Psychology; Psychiatry GA 096US UT WOS:000315430700004 PM 23299116 ER PT J AU Chan, AL Schnelle, SR AF Chan, Alex Lipchen Schnelle, Stephen R. TI Fusing concurrent visible and infrared videos for improved tracking performance SO OPTICAL ENGINEERING LA English DT Article DE infrared imagery; image fusion; target detection; target tracking ID IMAGE FUSION; COLOR AB Visible and infrared video cameras are the most common imaging sensors used for video surveillance systems. Fusing concurrent visible and infrared imageries may further improve the overall detection and tracking performance of a video surveillance system. We performed image fusion using 13 pixel-based image fusion algorithms and examined their effects on the detection and tracking performance of a given target tracker. We identified five fusion methods that produced significantly better performance, three of which also managed to achieve that with a relatively high efficiency. (C) 2013 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.OE.52.1.017004] C1 [Chan, Alex Lipchen] USA, Res Lab, Attent RDRL SES E, Adelphi, MD 20783 USA. [Schnelle, Stephen R.] Rice Univ, Houston, TX 77251 USA. RP Chan, AL (reprint author), USA, Res Lab, Attent RDRL SES E, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM Alex.L.Chan.Civ@mail.mil FU U.S. Army Research Office MURI [W311NF-07-1-0185]; National Science Foundation; National Defense Science and Engineering Graduate Fellowship Program; Texas Instruments Leadership University Program FX This work was partially supported by the U.S. Army Research Office MURI W311NF-07-1-0185 grant, National Science Foundation Graduate Fellowship Program, National Defense Science and Engineering Graduate Fellowship Program, and the Texas Instruments Leadership University Program. NR 19 TC 4 Z9 4 U1 1 U2 12 PU SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS PI BELLINGHAM PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98225 USA SN 0091-3286 J9 OPT ENG JI Opt. Eng. PD JAN PY 2013 VL 52 IS 1 AR 017004 DI 10.1117/1.OE.52.1.017004 PG 12 WC Optics SC Optics GA 092VY UT WOS:000315152300044 ER PT J AU Barber, PS Griggs, CS Bonner, JR Rogers, RD AF Barber, Patrick S. Griggs, Chris S. Bonner, Jonathan R. Rogers, Robin D. TI Electrospinning of chitin nanofibers directly from an ionic liquid extract of shrimp shells SO GREEN CHEMISTRY LA English DT Article ID FIBER FORMATION; CHITOSAN NANOFIBERS; DISSOLUTION; CELLULOSE; SOLVENT; FILMS AB High molecular weight chitin fibers were electrospun in a one-pot process directly from a 1-ethyl-3-methylimidazolium acetate solution of chitin extracted from dried shrimp shell. Such a technology obviates the need not only for the many chemicals and the energy used in industrial isolation of chitin from crustacean shells but also saves the chemicals, energy, and time needed to prepare chitin spinning dopes. C1 [Barber, Patrick S.; Griggs, Chris S.; Rogers, Robin D.] Univ Alabama, Ctr Green Mfg, Tuscaloosa, AL 35487 USA. [Barber, Patrick S.; Griggs, Chris S.; Rogers, Robin D.] Univ Alabama, Dept Chem, Tuscaloosa, AL 35487 USA. [Griggs, Chris S.] USA, ERDC Environm Lab, Vicksburg, MS 39180 USA. [Bonner, Jonathan R.] CFM Grp LLC, Tuscaloosa, AL 35401 USA. RP Barber, PS (reprint author), Univ Alabama, Ctr Green Mfg, Tuscaloosa, AL 35487 USA. EM rdrogers@as.ua.edu RI Rogers, Robin/C-8265-2013 OI Rogers, Robin/0000-0001-9843-7494 FU DOE Office of Nuclear Energy's Nuclear Energy University Programs [120427, 3123] FX The authors would like to thank the DOE Office of Nuclear Energy's Nuclear Energy University Programs (Sub-Contract - #120427, Project - # 3123) for project funding and Dr Kim Lackey and the Optical Analysis Facility at The University of Alabama for microscopy support. For the graphic design of the table of contents image the authors would like to thank Kate Barber. NR 36 TC 35 Z9 36 U1 9 U2 109 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 1463-9262 J9 GREEN CHEM JI Green Chem. PY 2013 VL 15 IS 3 BP 601 EP 607 DI 10.1039/c2gc36582k PG 7 WC Chemistry, Multidisciplinary; GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY SC Chemistry; Science & Technology - Other Topics GA 095TA UT WOS:000315356400004 ER PT J AU Patel, J Dorneich, MC Mott, D Bahrami, A Giammanco, C AF Patel, Jitu Dorneich, Michael C. Mott, David Bahrami, Ali Giammanco, Cheryl TI Improving Coalition Planning by Making Plans Alive SO IEEE INTELLIGENT SYSTEMS LA English DT Article ID AUTOMATION C1 [Dorneich, Michael C.] Honeywell Labs, Morristown, NJ USA. [Mott, David] IBM Hursley, Emerging Technol Serv Grp, Winchester, Hants, England. [Bahrami, Ali] Boeing Res & Technol, Chicago, IL USA. [Giammanco, Cheryl] USA, Res Lab, Washington, DC USA. EM jmpatel@dstl.gov.uk; dorneich@iastate.edu; mottd@uk.ibm.com; ali.bahrami@boeing.com; cheryl.giammanco@us.army.mil OI Dorneich, Michael/0000-0001-6386-4787 FU US Army Research Laboratory; UK Ministry of Defence [W911NF-06-3-0001] FX Research sponsored by the US Army Research Laboratory and the UK Ministry of Defence was accomplished under agreement number W911NF-06-3-0001. The views and conclusions contained in this document are those of the authors and should not be interpreted as representing the official policies, either expressed or implied, of the US Army Research Laboratory, the US government, the UK Ministry of Defence, or the UK government. The US and UK governments are authorized to reproduce and distribute reprints for government purposes notwithstanding any copyright notation herein. We thank John A. Allen, Jun Yuan, Dave Braines, and Paul Smart for collaborations and conversations during the course of this work. NR 27 TC 2 Z9 2 U1 2 U2 6 PU IEEE COMPUTER SOC PI LOS ALAMITOS PA 10662 LOS VAQUEROS CIRCLE, PO BOX 3014, LOS ALAMITOS, CA 90720-1314 USA SN 1541-1672 EI 1941-1294 J9 IEEE INTELL SYST JI IEEE Intell. Syst. PD JAN-FEB PY 2013 VL 28 IS 1 BP 17 EP 25 PG 9 WC Computer Science, Artificial Intelligence; Engineering, Electrical & Electronic SC Computer Science; Engineering GA 083RL UT WOS:000314482800006 ER PT J AU Giammanco, C McGowan, R Kao, A Braines, D Poteet, SR Pham, T Xue, P AF Giammanco, Cheryl McGowan, Ray Kao, Anne Braines, Dave Poteet, Stephen R. Tien Pham Xue, Ping TI Knowledge Management for Coalition Information Sharing at the Network Edge SO IEEE INTELLIGENT SYSTEMS LA English DT Article C1 [Giammanco, Cheryl] USA, Res Lab, HRED, Washington, DC 20310 USA. [McGowan, Ray] USA, Mission Command Div, Command Power & Integrat Directorate, Commun Elect Res Dev & Engn Ctr, Washington, DC USA. [Kao, Anne] Boeing Res & Technol, Text Min Projects, Chicago, IL USA. [Braines, Dave] IBM Corp, Emerging Technol Serv Team, Armonk, NY USA. [Poteet, Stephen R.; Xue, Ping] Boeing Res & Technol, Chicago, IL USA. [Tien Pham] USA, Networked Sensing & Fus Branch, Res Lab, Washington, DC USA. RP Giammanco, C (reprint author), USA, Res Lab, HRED, Washington, DC 20310 USA. EM cheryl.giammanco@us.army.mil; ray.mcgowan@us.army.mil; anne.kao@boeing.com; dave_braines@uk.ibm.com; stephen.r.poteet@boeing.com; tien.pham1.civ@mail.mil; ping.xue@boeing.com FU US Army Research Laboratory; UK Ministry of Defence [W911NF-06-3-0001] FX This research was sponsored by the US Army Research Laboratory and the UK Ministry of Defence and was accomplished under agreement number W911NF-06-3-0001. The views and conclusions contained in this document are those of the authors and should not be interpreted as representing the official policies, either expressed or implied, of the US Army Research Laboratory, the US government, the UK Ministry of Defence, or the UK government. The US and UK governments are authorized to reproduce and distribute reprints for government purposes notwithstanding any copyright notation herein. NR 26 TC 0 Z9 0 U1 1 U2 21 PU IEEE COMPUTER SOC PI LOS ALAMITOS PA 10662 LOS VAQUEROS CIRCLE, PO BOX 3014, LOS ALAMITOS, CA 90720-1314 USA SN 1541-1672 EI 1941-1294 J9 IEEE INTELL SYST JI IEEE Intell. Syst. PD JAN-FEB PY 2013 VL 28 IS 1 BP 26 EP 33 PG 8 WC Computer Science, Artificial Intelligence; Engineering, Electrical & Electronic SC Computer Science; Engineering GA 083RL UT WOS:000314482800007 ER PT J AU Preece, A Norman, T de Mel, G Pizzocaro, D Sensoy, M Pham, T AF Preece, Alun Norman, Tim de Mel, Geeth Pizzocaro, Diego Sensoy, Murat Tien Pham TI Agilely Assigning Sensing Assets to Mission Tasks in a Coalition Context SO IEEE INTELLIGENT SYSTEMS LA English DT Article C1 [Preece, Alun; Pizzocaro, Diego] Cardiff Univ, Cardiff CF10 3AX, S Glam, Wales. [Norman, Tim] Univ Aberdeen, Aberdeen AB9 1FX, Scotland. [Sensoy, Murat] Ozyegin Univ, Istanbul, Turkey. [Tien Pham] USA, Networked Sensing & Fus Branch, Res Lab, Washington, DC USA. RP Preece, A (reprint author), Cardiff Univ, Cardiff CF10 3AX, S Glam, Wales. EM a.d.preece@cs.cardiff.ac.uk; t.j.norman@abdn.ac.uk; grdemel@us.ibm.com; d.pizzocaro@cs.cardiff.ac.uk; murat.sensoy@ozyegin.edu.tr; tien.pham1.civ@mail.mil FU US Army Research Laboratory; UK Ministry of Defence [W911NF-06-3-0001] FX This research was sponsored by the US Army Research Laboratory and the UK Ministry of Defence and was accomplished under agreement number W911NF-06-3-0001. The views and conclusions contained in this document are those of the authors and should not be interpreted as representing the official policies, either expressed or implied, of the US Army Research Laboratory, the US government, the UK Ministry of Defence, or the UK government. The US and UK governments are authorized to reproduce and distribute reprints for government purposes notwithstanding any copyright notation herein. NR 10 TC 8 Z9 8 U1 0 U2 4 PU IEEE COMPUTER SOC PI LOS ALAMITOS PA 10662 LOS VAQUEROS CIRCLE, PO BOX 3014, LOS ALAMITOS, CA 90720-1314 USA SN 1541-1672 J9 IEEE INTELL SYST JI IEEE Intell. Syst. PD JAN-FEB PY 2013 VL 28 IS 1 BP 57 EP 63 PG 7 WC Computer Science, Artificial Intelligence; Engineering, Electrical & Electronic SC Computer Science; Engineering GA 083RL UT WOS:000314482800011 ER PT J AU Lindsey, CY Brown, JE Torabazar, NR Smith, LA AF Lindsey, Changhong Y. Brown, J. Edward Torabazar, Nahid R. Smith, Leonard A. TI EL4 Cell-Based Colorimetric Toxin Neutralization Activity Assays for Determination of Neutralizing Anti-Ricin Antibodies SO JOURNAL OF AOAC INTERNATIONAL LA English DT Article ID ANTHRAX VACCINE; VALIDATION; TOXICITY; HUMANS; ELISA; SERA AB A recombinant ricin toxin A-chain 1-33/44-198 vaccine (RVEc (TM)), developed at the United States Army Medical Research Institute of Infectious Diseases as a vaccine candidate, is under investigation in a phase 1 clinical study. To effectively evaluate the immunogenicity of this ricin vaccine and to eliminate the use of radioactive material, an EL4 cell-based colorimetric toxin neutralization activity (TNA) assay using a Cell Titer 96 (R) AQ(ueous) One Solution Cell Proliferation Assay Reagent has been developed, optimized, and applied in the vaccine efficacy studies. The TNA assay measures the protective neutralizing anti-ricin antibodies in animal sera by determining the cell viability after ricin exposure in the assay system and comparing it to a purified mouse polyclonal anti-ricin IgG standard curve. The standard curve of the anti-ricin TNA assay closely fits a four-parameter logistic regression model. The unknown test sample concentration was expressed as mu g/mL, but not the 50% effective concentration (EC50), which was determined by most TNA assays. The neutralizing endpoint titers, not the 50% effective dilution (ED50), of human specimens were measured with the TNA assay in support of the clinical study of the RVEc vaccine. The optimal amount of ricin toxin, EL4 cells, and concentration of standards used in the assay system was established to minimize false-negative and false-positive results of serum specimens from the nonclinical and clinical studies of RVEc. The testing conditions were adjusted to optimize assay performance. The colorimetric TNA assay replaced a radioactive TNA assay previously used in the ricin vaccine studies. C1 [Lindsey, Changhong Y.; Brown, J. Edward; Torabazar, Nahid R.; Smith, Leonard A.] USA, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA. [Smith, Leonard A.] USA, Med Res & Mat Command, Ft Detrick, MD 21702 USA. RP Lindsey, CY (reprint author), USA, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA. EM changhong.lindsey2@us.army.mil FU Joint Science and Technology Office for Chemical-Biological Defense FX This work was supported by the Joint Science and Technology Office for Chemical-Biological Defense. We thank Rene Aguirre (USAMRIID) for his technical support, and Ronald Reisler (USAMRIID), Philip Pittman (USAMRIID), Robert Wannemacher (USAMRIID), Thomas Horn (IIT Research Inst., Chicago, IL), Wendy Giles (USAMRIID), and Michelle Canby (USAMRIID) for providing clinical and animal serum samples. NR 27 TC 2 Z9 2 U1 1 U2 4 PU AOAC INT PI GAITHERSBURG PA 481 N FREDRICK AVE, STE 500, GAITHERSBURG, MD 20877-2504 USA SN 1060-3271 J9 J AOAC INT JI J. AOAC Int. PD JAN-FEB PY 2013 VL 96 IS 1 BP 147 EP 154 DI 10.5740/jaoacint.12-285 PG 8 WC Chemistry, Analytical; Food Science & Technology SC Chemistry; Food Science & Technology GA 094HT UT WOS:000315254300023 PM 23513970 ER PT J AU Kipfmueller, F Wyen, H Borgman, MA Spinella, PC Wirth, S Maegele, M AF Kipfmueller, F. Wyen, H. Borgman, M. A. Spinella, P. C. Wirth, S. Maegele, M. TI Epidemiology, Risk Stratification and Outcome of Severe Pediatric Trauma SO KLINISCHE PADIATRIE LA German DT Review DE pediatric trauma; risk stratification; prognosis; outcome ID ADMISSION BASE DEFICIT; BRAIN-INJURY; HEAD-INJURY; HEMOCOAGULATIVE DISORDERS; ACUTE COAGULOPATHY; ENZYME-ACTIVITY; SCORE; CHILDREN; MORTALITY; CARE AB Accidents and trauma are the leading cause of hospital admissions and major contributors to mortality in children and adolescents. There are age-specific injury patterns and differences in the clinical presentation of pediatric trauma and treatment both at the scene and in the emergency department can be observed. In general, pediatric trauma-scores to appreciate injury severity are adapted from the adult population. The most important factor to increase mortality in the severely injured pediatric population is the extent of a concomitant traumatic brain injury (TBI). In addition, the acute trauma-associated coagulopathy, which is triggered multifactorial, is an independent prognostic marker for mortality in severe trauma. The complexity of all currently available trauma-scores for the pediatric population is one reason why these scores are not unequivocal recommended for the early use in pediatric trauma care. The pediatric BIG-Score was developed to allow an early prognostic stratification for pediatric trauma patients and includes with base excess (BE), INR (International Normalized Ratio) and GCS (Glasgow Coma Scale) relevant prognostic factors for poor outcome. Early risk stratification is crucial in pediatric trauma due to mortality rates ranging between 9% and 15% and with 50% of all fatalities to occur within the first 24h of hospital admission. C1 [Kipfmueller, F.] Univ Bonn, Zentrum Kinderheilkunde, Abt Neonatol, Bonn, Germany. [Wyen, H.] Klinikum Johann Wolfgang Goethe Univ, Klin Unfallchirurg Hand & Rekonstrukt Chirurg, Frankfurt, Germany. [Borgman, M. A.] Brooke Army Med Ctr, MCHE DP PICU, Ft Sam Houston, TX 78234 USA. [Spinella, P. C.] Washington Univ, St Louis Childrens Hosp, Sch Med, Dept Pediat, St Louis, MO 63110 USA. [Wirth, S.] Univ Witten Herdecke, Zentrum Kinder & Jugendmed, Helios Klinikum Wuppertal, Wuppertal, Germany. [Maegele, M.] Univ Witten Herdecke, Klinikum Koln Merheim, Klin Unfallchirurg Orthopadie & Sporttraumatol, D-51109 Cologne, Germany. [Maegele, M.] Univ Witten Herdecke, IFOM, D-51109 Cologne, Germany. RP Maegele, M (reprint author), Univ Witten Herdecke, Klinikum Koln Merheim, Klin Unfallchirurg Orthopadie & Sporttraumatol, Ostmerheimerstr 200, D-51109 Cologne, Germany. EM Marc.Maegele@t-online.de RI Borgman, Matthew/L-9477-2015 OI Borgman, Matthew/0000-0002-2008-7380 NR 52 TC 4 Z9 5 U1 0 U2 7 PU GEORG THIEME VERLAG KG PI STUTTGART PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY SN 0300-8630 J9 KLIN PADIATR JI Klinische Padiatr. PD JAN PY 2013 VL 225 IS 1 BP 34 EP 40 DI 10.1055/s-0032-1329945 PG 7 WC Pediatrics SC Pediatrics GA 092PU UT WOS:000315135300008 PM 23203384 ER PT B AU Joines, WT Palmer, WD Bernhard, JT AF Joines, William T. Palmer, W. Devereux Bernhard, Jennifer T. BA Joines, WT Palmer, WD Bernhard, JT BF Joines, WT Palmer, WD Bernhard, JT TI Microwave Transmission Line Circuits INTRODUCTION SO MICROWAVE TRANSMISSION LINE CIRCUITS SE Artech House Microwave Library LA English DT Article; Book Chapter C1 [Joines, William T.] Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. [Joines, William T.] USAF, Wright Patterson AFB, OH USA. [Joines, William T.; Palmer, W. Devereux; Bernhard, Jennifer T.] IEEE, New York, NY USA. [Palmer, W. Devereux] USA, Res Off, Adelphi, MD USA. [Bernhard, Jennifer T.] Univ Illinois, Dept Elect & Comp Engn, Electromagnet Lab, Urbana, IL 61801 USA. [Bernhard, Jennifer T.] IEEE Antennas & Propagat Soc, Culver City, CA USA. RP Joines, WT (reprint author), Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. NR 12 TC 0 Z9 0 U1 0 U2 0 PU ARTECH HOUSE PI NORWOOD PA 685 CANTON ST, NORWOOD, MA 02062 USA BN 978-1-60807-569-0 J9 ARTECH HSE MICROW LI PY 2013 BP 1 EP 21 PG 21 WC Physics, Applied; Telecommunications SC Physics; Telecommunications GA BDO77 UT WOS:000314254000002 ER PT B AU Joines, WT Palmer, WD Bernhard, JT AF Joines, William T. Palmer, W. Devereux Bernhard, Jennifer T. BA Joines, WT Palmer, WD Bernhard, JT BF Joines, WT Palmer, WD Bernhard, JT TI Microwave Transmission Line Circuits PREFACE SO MICROWAVE TRANSMISSION LINE CIRCUITS SE Artech House Microwave Library LA English DT Editorial Material; Book Chapter C1 [Joines, William T.] Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. [Joines, William T.] USAF, Wright Patterson AFB, OH USA. [Joines, William T.; Palmer, W. Devereux; Bernhard, Jennifer T.] IEEE, New York, NY USA. [Palmer, W. Devereux] USA, Res Off, Adelphi, MD USA. [Bernhard, Jennifer T.] Univ Illinois, Dept Elect & Comp Engn, Electromagnet Lab, Urbana, IL 61801 USA. [Bernhard, Jennifer T.] IEEE Antennas & Propagat Soc, Culver City, CA USA. RP Joines, WT (reprint author), Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ARTECH HOUSE PI NORWOOD PA 685 CANTON ST, NORWOOD, MA 02062 USA BN 978-1-60807-569-0 J9 ARTECH HSE MICROW LI PY 2013 BP IX EP X PG 2 WC Physics, Applied; Telecommunications SC Physics; Telecommunications GA BDO77 UT WOS:000314254000001 ER PT B AU Joines, WT Palmer, WD Bernhard, JT AF Joines, William T. Palmer, W. Devereux Bernhard, Jennifer T. BA Joines, WT Palmer, WD Bernhard, JT BF Joines, WT Palmer, WD Bernhard, JT TI MICROWAVE TRANSMISSION LINES SO MICROWAVE TRANSMISSION LINE CIRCUITS SE Artech House Microwave Library LA English DT Article; Book Chapter C1 [Joines, William T.] Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. [Joines, William T.] USAF, Wright Patterson AFB, OH USA. [Joines, William T.; Palmer, W. Devereux; Bernhard, Jennifer T.] IEEE, New York, NY USA. [Palmer, W. Devereux] USA, Res Off, Adelphi, MD USA. [Bernhard, Jennifer T.] Univ Illinois, Dept Elect & Comp Engn, Electromagnet Lab, Urbana, IL 61801 USA. [Bernhard, Jennifer T.] IEEE Antennas & Propagat Soc, Culver City, CA USA. RP Joines, WT (reprint author), Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. NR 10 TC 0 Z9 0 U1 0 U2 0 PU ARTECH HOUSE PI NORWOOD PA 685 CANTON ST, NORWOOD, MA 02062 USA BN 978-1-60807-569-0 J9 ARTECH HSE MICROW LI PY 2013 BP 23 EP 67 PG 45 WC Physics, Applied; Telecommunications SC Physics; Telecommunications GA BDO77 UT WOS:000314254000003 ER PT B AU Joines, WT Palmer, WD Bernhard, JT AF Joines, William T. Palmer, W. Devereux Bernhard, Jennifer T. BA Joines, WT Palmer, WD Bernhard, JT BF Joines, WT Palmer, WD Bernhard, JT TI TRANSMISSION LINE SEGMENTS AS NETWORK ELEMENTS SO MICROWAVE TRANSMISSION LINE CIRCUITS SE Artech House Microwave Library LA English DT Article; Book Chapter C1 [Joines, William T.] Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. [Joines, William T.] USAF, Wright Patterson AFB, OH USA. [Joines, William T.; Palmer, W. Devereux; Bernhard, Jennifer T.] IEEE, New York, NY USA. [Palmer, W. Devereux] USA, Res Off, Adelphi, MD USA. [Bernhard, Jennifer T.] Univ Illinois, Dept Elect & Comp Engn, Electromagnet Lab, Urbana, IL 61801 USA. [Bernhard, Jennifer T.] IEEE Antennas & Propagat Soc, Culver City, CA USA. RP Joines, WT (reprint author), Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. NR 10 TC 0 Z9 0 U1 0 U2 0 PU ARTECH HOUSE PI NORWOOD PA 685 CANTON ST, NORWOOD, MA 02062 USA BN 978-1-60807-569-0 J9 ARTECH HSE MICROW LI PY 2013 BP 69 EP 95 PG 27 WC Physics, Applied; Telecommunications SC Physics; Telecommunications GA BDO77 UT WOS:000314254000004 ER PT B AU Joines, WT Palmer, WD Bernhard, JT AF Joines, William T. Palmer, W. Devereux Bernhard, Jennifer T. BA Joines, WT Palmer, WD Bernhard, JT BF Joines, WT Palmer, WD Bernhard, JT TI MATRIX REPRESENTATION OF MICROWAVE NETWORKS SO MICROWAVE TRANSMISSION LINE CIRCUITS SE Artech House Microwave Library LA English DT Article; Book Chapter C1 [Joines, William T.] Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. [Joines, William T.] USAF, Wright Patterson AFB, OH USA. [Joines, William T.; Palmer, W. Devereux; Bernhard, Jennifer T.] IEEE, New York, NY USA. [Palmer, W. Devereux] USA, Res Off, Adelphi, MD USA. [Bernhard, Jennifer T.] Univ Illinois, Dept Elect & Comp Engn, Electromagnet Lab, Urbana, IL 61801 USA. [Bernhard, Jennifer T.] IEEE Antennas & Propagat Soc, Culver City, CA USA. RP Joines, WT (reprint author), Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. NR 16 TC 0 Z9 0 U1 0 U2 0 PU ARTECH HOUSE PI NORWOOD PA 685 CANTON ST, NORWOOD, MA 02062 USA BN 978-1-60807-569-0 J9 ARTECH HSE MICROW LI PY 2013 BP 97 EP 130 PG 34 WC Physics, Applied; Telecommunications SC Physics; Telecommunications GA BDO77 UT WOS:000314254000005 ER PT B AU Joines, WT Palmer, WD Bernhard, JT AF Joines, William T. Palmer, W. Devereux Bernhard, Jennifer T. BA Joines, WT Palmer, WD Bernhard, JT BF Joines, WT Palmer, WD Bernhard, JT TI SYNTHESIS AND DESIGN OF FREQUENCY-FILTERING NETWORKS SO MICROWAVE TRANSMISSION LINE CIRCUITS SE Artech House Microwave Library LA English DT Article; Book Chapter C1 [Joines, William T.] Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. [Joines, William T.] USAF, Wright Patterson AFB, OH USA. [Joines, William T.; Palmer, W. Devereux; Bernhard, Jennifer T.] IEEE, New York, NY USA. [Palmer, W. Devereux] USA, Res Off, Adelphi, MD USA. [Bernhard, Jennifer T.] Univ Illinois, Dept Elect & Comp Engn, Electromagnet Lab, Urbana, IL 61801 USA. [Bernhard, Jennifer T.] IEEE Antennas & Propagat Soc, Culver City, CA USA. RP Joines, WT (reprint author), Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. NR 18 TC 0 Z9 0 U1 0 U2 0 PU ARTECH HOUSE PI NORWOOD PA 685 CANTON ST, NORWOOD, MA 02062 USA BN 978-1-60807-569-0 J9 ARTECH HSE MICROW LI PY 2013 BP 131 EP 171 PG 41 WC Physics, Applied; Telecommunications SC Physics; Telecommunications GA BDO77 UT WOS:000314254000006 ER PT B AU Joines, WT Palmer, WD Bernhard, JT AF Joines, William T. Palmer, W. Devereux Bernhard, Jennifer T. BA Joines, WT Palmer, WD Bernhard, JT BF Joines, WT Palmer, WD Bernhard, JT TI BROADBAND IMPEDANCE-MATCHING NETWORKS SO MICROWAVE TRANSMISSION LINE CIRCUITS SE Artech House Microwave Library LA English DT Article; Book Chapter C1 [Joines, William T.] Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. [Joines, William T.] USAF, Wright Patterson AFB, OH USA. [Joines, William T.; Palmer, W. Devereux; Bernhard, Jennifer T.] IEEE, New York, NY USA. [Palmer, W. Devereux] USA, Res Off, Adelphi, MD USA. [Bernhard, Jennifer T.] Univ Illinois, Dept Elect & Comp Engn, Electromagnet Lab, Urbana, IL 61801 USA. [Bernhard, Jennifer T.] IEEE Antennas & Propagat Soc, Culver City, CA USA. RP Joines, WT (reprint author), Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. NR 12 TC 0 Z9 0 U1 0 U2 0 PU ARTECH HOUSE PI NORWOOD PA 685 CANTON ST, NORWOOD, MA 02062 USA BN 978-1-60807-569-0 J9 ARTECH HSE MICROW LI PY 2013 BP 173 EP 195 PG 23 WC Physics, Applied; Telecommunications SC Physics; Telecommunications GA BDO77 UT WOS:000314254000007 ER PT B AU Joines, WT Palmer, WD Bernhard, JT AF Joines, William T. Palmer, W. Devereux Bernhard, Jennifer T. BA Joines, WT Palmer, WD Bernhard, JT BF Joines, WT Palmer, WD Bernhard, JT TI COMBINING, DIVIDING, AND COUPLING CIRCUITS SO MICROWAVE TRANSMISSION LINE CIRCUITS SE Artech House Microwave Library LA English DT Article; Book Chapter C1 [Joines, William T.] Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. [Joines, William T.] USAF, Wright Patterson AFB, OH USA. [Joines, William T.; Palmer, W. Devereux; Bernhard, Jennifer T.] IEEE, New York, NY USA. [Palmer, W. Devereux] USA, Res Off, Adelphi, MD USA. [Bernhard, Jennifer T.] Univ Illinois, Dept Elect & Comp Engn, Electromagnet Lab, Urbana, IL 61801 USA. [Bernhard, Jennifer T.] IEEE Antennas & Propagat Soc, Culver City, CA USA. RP Joines, WT (reprint author), Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. NR 11 TC 0 Z9 0 U1 0 U2 0 PU ARTECH HOUSE PI NORWOOD PA 685 CANTON ST, NORWOOD, MA 02062 USA BN 978-1-60807-569-0 J9 ARTECH HSE MICROW LI PY 2013 BP 197 EP 223 PG 27 WC Physics, Applied; Telecommunications SC Physics; Telecommunications GA BDO77 UT WOS:000314254000008 ER PT B AU Joines, WT Palmer, WD Bernhard, JT AF Joines, William T. Palmer, W. Devereux Bernhard, Jennifer T. BA Joines, WT Palmer, WD Bernhard, JT BF Joines, WT Palmer, WD Bernhard, JT TI TRANSMISSION LINE APPLICATIONS IN ACTIVE CIRCUITS SO MICROWAVE TRANSMISSION LINE CIRCUITS SE Artech House Microwave Library LA English DT Article; Book Chapter ID MICROWAVE GAAS-MESFETS; AMPLIFIERS C1 [Joines, William T.] Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. [Joines, William T.] USAF, Wright Patterson AFB, OH USA. [Joines, William T.; Palmer, W. Devereux; Bernhard, Jennifer T.] IEEE, New York, NY USA. [Palmer, W. Devereux] USA, Res Off, Adelphi, MD USA. [Bernhard, Jennifer T.] Univ Illinois, Dept Elect & Comp Engn, Electromagnet Lab, Urbana, IL 61801 USA. [Bernhard, Jennifer T.] IEEE Antennas & Propagat Soc, Culver City, CA USA. RP Joines, WT (reprint author), Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. NR 15 TC 0 Z9 0 U1 0 U2 0 PU ARTECH HOUSE PI NORWOOD PA 685 CANTON ST, NORWOOD, MA 02062 USA BN 978-1-60807-569-0 J9 ARTECH HSE MICROW LI PY 2013 BP 225 EP 262 PG 38 WC Physics, Applied; Telecommunications SC Physics; Telecommunications GA BDO77 UT WOS:000314254000009 ER PT B AU Joines, WT Palmer, WD Bernhard, JT AF Joines, William T. Palmer, W. Devereux Bernhard, Jennifer T. BA Joines, WT Palmer, WD Bernhard, JT BF Joines, WT Palmer, WD Bernhard, JT TI NORMALIZED ELEMENT VALUES FOR LOWPASS FILTERS WITH BUTTERWORTH, CHEBYSHEV, AND BESSEL RESPONSES SO MICROWAVE TRANSMISSION LINE CIRCUITS SE Artech House Microwave Library LA English DT Article; Book Chapter C1 [Joines, William T.] Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. [Joines, William T.] USAF, Wright Patterson AFB, OH USA. [Joines, William T.; Palmer, W. Devereux; Bernhard, Jennifer T.] IEEE, New York, NY USA. [Palmer, W. Devereux] USA, Res Off, Adelphi, MD USA. [Bernhard, Jennifer T.] Univ Illinois, Dept Elect & Comp Engn, Electromagnet Lab, Urbana, IL 61801 USA. [Bernhard, Jennifer T.] IEEE Antennas & Propagat Soc, Culver City, CA USA. RP Joines, WT (reprint author), Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. NR 2 TC 0 Z9 0 U1 0 U2 0 PU ARTECH HOUSE PI NORWOOD PA 685 CANTON ST, NORWOOD, MA 02062 USA BN 978-1-60807-569-0 J9 ARTECH HSE MICROW LI PY 2013 BP 263 EP 275 PG 13 WC Physics, Applied; Telecommunications SC Physics; Telecommunications GA BDO77 UT WOS:000314254000010 ER PT B AU Joines, WT Palmer, WD Bernhard, JT AF Joines, William T. Palmer, W. Devereux Bernhard, Jennifer T. BA Joines, WT Palmer, WD Bernhard, JT BF Joines, WT Palmer, WD Bernhard, JT TI MICROSTRIP CHARACTERISTIC IMPEDANCE AND EFFECTIVE epsilon(r) VERSUS w/h SO MICROWAVE TRANSMISSION LINE CIRCUITS SE Artech House Microwave Library LA English DT Article; Book Chapter ID LINE C1 [Joines, William T.] Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. [Joines, William T.] USAF, Wright Patterson AFB, OH USA. [Joines, William T.; Palmer, W. Devereux; Bernhard, Jennifer T.] IEEE, New York, NY USA. [Palmer, W. Devereux] USA, Res Off, Adelphi, MD USA. [Bernhard, Jennifer T.] Univ Illinois, Dept Elect & Comp Engn, Electromagnet Lab, Urbana, IL 61801 USA. [Bernhard, Jennifer T.] IEEE Antennas & Propagat Soc, Culver City, CA USA. RP Joines, WT (reprint author), Duke Univ, Dept Elect & Comp Engn, Sensing & Signals Grp, Durham, NC 27706 USA. NR 3 TC 0 Z9 0 U1 0 U2 0 PU ARTECH HOUSE PI NORWOOD PA 685 CANTON ST, NORWOOD, MA 02062 USA BN 978-1-60807-569-0 J9 ARTECH HSE MICROW LI PY 2013 BP 277 EP 293 PG 17 WC Physics, Applied; Telecommunications SC Physics; Telecommunications GA BDO77 UT WOS:000314254000011 ER PT J AU Stewart, IJ Morrow, BD Tilley, MA Snow, BD Gisler, C Kramer, KW Aden, JK Renz, EM Chung, KK AF Stewart, Ian J. Morrow, Benjamin D. Tilley, Molly A. Snow, Brian D. Gisler, Christopher Kramer, Keith W. Aden, James K. Renz, Evan M. Chung, Kevin K. TI Dysnatremias and Survival in Adult Burn Patients: A Retrospective Analysis SO AMERICAN JOURNAL OF NEPHROLOGY LA English DT Article DE Acute kidney injury; Burn; Dysnatremia; Hypernatremia; Hyponatremia; Mortality ID INTENSIVE-CARE-UNIT; ACUTE KIDNEY INJURY; CRITICALLY-ILL PATIENTS; ACQUIRED HYPERNATREMIA; SERUM SODIUM; RISK-FACTOR; HYPONATREMIA; MORTALITY; OUTCOMES; PROGNOSIS AB Background/Aims: Dysnatremias have been evaluated in many populations and have been found to be significantly associated with mortality. However, this relationship has not been well described in the burn population. Methods: Admissions to the burn center at our institution from January 2003 to December 2008 were examined. Independent variables included gender, age, percentage total body surface area burned (%TBSA), percentage of third-degree burn, inhalation injury, injury severity score (ISS), Acute Kidney Injury Network (AKIN) stage, hypernatremia, and hyponatremia. They were examined via Cox proportional hazard regression models against death. Moderate to severe hypo-and hypernatremia were defined as serum sodium < 130 and > 150 mmol/l, respectively. Results: In 1,969 subjects with a mean age of 36.3 +/- 16.4 years, a median %TBSA of 9 (interquartile range 4-20) and a median ISS of 5 (interquartile range 1-16) hypernatremia occurred in 9.9% (n = 194), while hyponatremia occurred in 6.8% (n = 134) with mortality rates of 33.5 and 13.8%, respectively. Patients without a dysnatremia had a mortality rate of 4.3%. On Cox proportional hazard regression age, %TBSA, ISS, and AKIN stage were found to be significant predictors of mortality. Hypernatremia (HR 2.00, 95% CI 1.212-3.31; p = 0.0066), but not hyponatremia (HR 1.72, 95% CI 0.89-3.34; p = 0.1068) was associated with mortality. Conclusions: In the burn population, hypernatremia, but not hyponatremia, is an independent predictor of mortality. C1 [Stewart, Ian J.; Morrow, Benjamin D.; Tilley, Molly A.; Snow, Brian D.; Kramer, Keith W.] San Antonio Mil Med Ctr, Ft Sam Houston, TX 78234 USA. [Gisler, Christopher] San Antonio Kidney Dis Ctr, San Antonio, TX USA. [Aden, James K.; Renz, Evan M.; Chung, Kevin K.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Renz, Evan M.; Chung, Kevin K.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA. RP Stewart, IJ (reprint author), San Antonio Mil Med Ctr, ATTN Nephrol, 3551 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA. EM ian.stewart@amedd.army.mil NR 25 TC 4 Z9 5 U1 0 U2 0 PU KARGER PI BASEL PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND SN 0250-8095 J9 AM J NEPHROL JI Am. J. Nephrol. PY 2013 VL 37 IS 1 BP 59 EP 64 DI 10.1159/000346206 PG 6 WC Urology & Nephrology SC Urology & Nephrology GA 087TO UT WOS:000314786300007 PM 23327805 ER PT J AU Rosenberg, DK Swift, R AF Rosenberg, Daniel K. Swift, Roberta TI Post-Emergence Behavior of Hatchling Western Pond Turtles (Actinemys marmorata) in Western Oregon SO AMERICAN MIDLAND NATURALIST LA English DT Article ID LIFE-HISTORY STAGE; TERRAPINS MALACLEMYS-TERRAPIN; PREDATION; EMERGENCE; MOVEMENTS; SURVIVAL; SIZE; NEST AB Understanding space-use patterns of freshwater turtle hatchlings is critical to guide conservation efforts, yet little is known because of the difficulties in studying this early life-history stage. We investigated post-emergence movements and habitat associations of western pond turtles (Actinemys marmorata) at two study sites in western Oregon using microtransmitters and harmonic radar methods. Hatchlings delayed emergence until spring, with few exceptions. Hatchlings typically remained within 2 m of nests for as long as 59 d after initial emergence. During migration from their nests to aquatic habitat, hatchlings embedded themselves in soil for up to 22 d at stop-over sites. Movements between successive stop-over sites averaged 27 m. Although the number of days turtles remained within 2 m of their nest following emergence varied widely among and within nests, hatchlings entered aquatic habitat relatively synchronously. Hatchlings entered aquatic habitat on average 49 d after initial emergence, and traveled an average of 89 m from their nest site. Hatchlings detected in water were always within 1 m of shore and in areas with dense submerged vegetation and woody debris. Because of delayed emergence and extended post-emergent use of the area adjacent to nests, managers must consider the trade-offs of managing vegetation for nest habitat and the potential harm to hatchlings by vegetation management near nests. C1 [Rosenberg, Daniel K.] Oregon Wildlife Inst, Corvallis, OR 97339 USA. [Swift, Roberta] USA, Corps Engineers, Willamette Valley Project, Junction City, OR 97488 USA. RP Rosenberg, DK (reprint author), Oregon Wildlife Inst, Corvallis, OR 97339 USA. EM dan@oregonwildlife.org FU U.S. Fish and Wildlife Service (Oregon State Office); U.S. Forest Service (Middle Fork Willamette Ranger District); U.S. Army Corps of Engineers; National Fish and Wildlife Foundation; Oregon Wildlife Heritage Foundation FX We thank D. and S. Banner, N. Dwyer, S. Green (deceased), L. Riley, J. Stegall, and D. Williams for field assistance; J. Schleier, and S. Stewart for logistical support; S. Barnes, K. Buhlmann, W. Gibbons, C. Rombough, E. Roskam, and C. Yee for discussions on field methods and drawing attention to relevant literature; K. Beal, J. Gervais, W. Gibbons, S. Mullin, D. Vesely, and two anonymous reviewers for constructive comments on earlier drafts; and the U.S. Fish and Wildlife Service (Oregon State Office), U.S. Forest Service (Middle Fork Willamette Ranger District), U.S. Army Corps of Engineers, National Fish and Wildlife Foundation, and the Oregon Wildlife Heritage Foundation for funding. Field methods followed the Guidelines for Use of Live Amphibians and Reptiles in Field Research and Oregon Department of Fish and Wildlife provided permits. NR 32 TC 2 Z9 2 U1 2 U2 25 PU AMER MIDLAND NATURALIST PI NOTRE DAME PA UNIV NOTRE DAME, BOX 369, ROOM 295 GLSC, NOTRE DAME, IN 46556 USA SN 0003-0031 J9 AM MIDL NAT JI Am. Midl. Nat. PD JAN PY 2013 VL 169 IS 1 BP 111 EP 121 PG 11 WC Biodiversity Conservation; Ecology SC Biodiversity & Conservation; Environmental Sciences & Ecology GA 069XF UT WOS:000313469700010 ER PT J AU Bertucci, MA Lee, SJ Gagne, MR AF Bertucci, Michael A. Lee, Stephen J. Gagne, Michel R. TI Thiourea-catalyzed aminolysis of N-acyl homoserine lactones SO CHEMICAL COMMUNICATIONS LA English DT Article ID RING-OPENING AMINOLYSIS; N-(3-OXODODECANOYL)-L-HOMOSERINE LACTONE; METAL-FREE; QUORUM; ORGANOCATALYSIS; COMMUNICATION; BACTERIA; INHIBITORS AB Thiourea catalysts accelerate aminolysis of N-acyl homoserine lactones (AHLs), molecules integral to bacterial quorum sensing. The catalysts afford rate enhancement of up to 10 times the control in CD3CN. Mild catalysis in other polar aprotic solvents is still observed, while the activity is attenuated in polar protic solvents. C1 [Bertucci, Michael A.; Gagne, Michel R.] Univ N Carolina, Dept Chem, Caudill & Kenan Labs, Chapel Hill, NC 27599 USA. [Lee, Stephen J.] USA, Res Off, Res Triangle Pk, NC 27709 USA. RP Gagne, MR (reprint author), Univ N Carolina, Dept Chem, Caudill & Kenan Labs, Campus Box 3290, Chapel Hill, NC 27599 USA. EM mgagne@unc.edu FU US Army Research Office FX We wish to acknowledge Dr Masa Matsumoto, Dr Silvia Bezer-Bratu and Dr Mee-Kyung Chung for their valuable insights and offer a special thanks to Dr Marcey L. Waters and the US Army Research Office for their support. NR 31 TC 4 Z9 4 U1 2 U2 38 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 1359-7345 J9 CHEM COMMUN JI Chem. Commun. PY 2013 VL 49 IS 20 BP 2055 EP 2057 DI 10.1039/c3cc00268c PG 3 WC Chemistry, Multidisciplinary SC Chemistry GA 087RP UT WOS:000314780200021 PM 23376901 ER PT J AU McCain, KNS AF McCain, Kathryn N. S. TI Moving Large River Ecology from Past Theories to Future Actions: A Review SO REVIEWS IN FISHERIES SCIENCE LA English DT Review DE adaptive management; ecological theory; large river; management; restoration ID ADAPTIVE MANAGEMENT; RESTORATION; ECOSYSTEMS; CONNECTIVITY; FRAMEWORK; CHALLENGE; ENHANCEMENT; LANDSCAPES; STANDARDS; RECOVERY AB Large river ecology has evolved through time, from perceiving rivers as big streams to accepting rivers as spatiotemporally diverse and complex ecosystems spanning terrestrial, aquatic, and socio-political realms. This review summarizes past and present concepts in large river ecology and highlights uncertainties facing the science and management of large rivers, and provides examples of tools (river restoration and adaptive management) that may be used to continue the advancement of large river ecology into the future. We need to ask, "Where do we go from here?" and, "How do we get there?" The science, management, and policy of large rivers are inseparable and decisions formulated by river stakeholders today will inevitably shape how rivers are studied and managed into the future. C1 USA, Corps Engineers, Reg Environm & Planning Div N, St Louis, MO 63103 USA. RP McCain, KNS (reprint author), USA, Corps Engineers, Reg Environm & Planning Div N, 1222 Spruce St, St Louis, MO 63103 USA. EM kathryn.mccain@usace.army.mil FU Upper Mississippi River Restoration-Environmental Management Program Long-Term Resource Monitoring Program FX I thank Dr. M. DeLong, Dr. D. Galat, R. Hrabik, Dr. B. Johnson, Dr. K. Lubinski, and Dr. R. Sparks, for their helpful comments during the transformation of the original white paper into a manuscript. Additionally, I acknowledge the Upper Mississippi River Restoration-Environmental Management Program Long-Term Resource Monitoring Program that supported my work on this effort. NR 59 TC 1 Z9 1 U1 2 U2 54 PU TAYLOR & FRANCIS INC PI PHILADELPHIA PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA SN 1064-1262 EI 1547-6553 J9 REV FISH SCI JI Rev. Fish. Sci. PY 2013 VL 21 IS 1 BP 39 EP 48 DI 10.1080/10641262.2012.753867 PG 10 WC Fisheries SC Fisheries GA 089EF UT WOS:000314891600003 ER PT J AU Viputtigul, K Tungpukdee, N Ruangareerate, T Luplertlop, N Wilairatana, P Gaywee, J Krudsood, S AF Viputtigul, Kwanjai Tungpukdee, Noppadon Ruangareerate, Toon Luplertlop, Natthanej Wilairatana, Polrat Gaywee, Jariyanart Krudsood, Srivicha TI C-TERMINAL POLYMORPHISM OF PLASMODIUM FALCIPARIUM MEROZOITE SURFACE PROTEIN-1 (MSP-1) FROM TAK PROVINCE, THAILAND SO SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH LA English DT Article DE Plasmodium falciparum; merzoite surface protein-1; polymorphism ID T-CELL EPITOPES; GENETIC DIVERSITY; ALLELIC DIVERSITY; TRIPEPTIDE REPEATS; MALARIA PARASITE; REGION; SEQUENCE; ANTIGEN; POPULATIONS; FRAGMENT AB This study was undertaken to ascertain the extent of polymorphism in the C-terminal region of Plasmodium falciparum merozoite surface protein (MSP-1) from 119 malaria patients in Tak Province on the western border of Thailand, who were admitted to the Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. P. falciparum infection was confirmed by microscopic examination of peripheral blood smears. Clinical manifestations were categorized into 2 groups: uncomplicated (94 cases) and complicated/severe (25 cases). A 1,040 basepair fragment of P. falciparum MSP-1 gene was compared with MSP-1 of reference strains retrieved from GenBank. The consensus sequences of MSP-1 block 16 showed it belonged to MAD20 genotype, which is the major allele of falciparum malaria from the western border of Thailand. MSP-1 block 16 amino acid fragment could be separated into 2 groups: similar and dissimilar to reference sequence. Four variations in MSP-1 block 16 were similar to 1494K, D1510G, D1556N, and K1696I. MSP-1 block 16 diversity is not significantly associated with clinical manifestation although MAD 20 genotype is the predominant genotype in this area. The genetic data of MSP1 gene of faciparum, malaria isolated from western Thai border contribute, to the existing genetic database of Thai P. falciparum strain. C1 [Viputtigul, Kwanjai; Luplertlop, Natthanej; Krudsood, Srivicha] Mahidol Univ, Fac Trop Med, Dept Trop Hyg, Bangkok 10400, Thailand. [Tungpukdee, Noppadon; Wilairatana, Polrat] Mahidol Univ, Fac Trop Med, Dept Clin Trop Med, Bangkok 10400, Thailand. [Viputtigul, Kwanjai; Ruangareerate, Toon; Gaywee, Jariyanart] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand. RP Krudsood, S (reprint author), Mahidol Univ, Fac Trop Med, Dept Trop Hyg, 420-6 Ratchawithi Rd, Bangkok 10400, Thailand. EM srivicha.kru@mahidol.ac.th FU Office of the High Education Commission; Mahidol University under the National Research Universities Initiative; National Center for Global Health and Medicine [21A107] FX We thank all the participants and staff of the Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University. This study was partially supported by the Office of the High Education Commission and Mahidol University under the National Research Universities Initiative and a grant of the National Center for Global Health and Medicine (Grant No. 21A107). NR 36 TC 0 Z9 0 U1 0 U2 2 PU SOUTHEAST ASIAN MINISTERS EDUC ORGANIZATION PI BANGKOK PA SEAMEO-TROPMED, 420-6 RAJVITHI RD,, BANGKOK 10400, THAILAND SN 0125-1562 J9 SE ASIAN J TROP MED JI Southeast Asian J. Trop. Med. Public Health PD JAN PY 2013 VL 44 IS 1 BP 1 EP 12 PG 12 WC Public, Environmental & Occupational Health; Infectious Diseases; Tropical Medicine SC Public, Environmental & Occupational Health; Infectious Diseases; Tropical Medicine GA 091TQ UT WOS:000315073100001 PM 23682431 ER PT J AU Satapathy, S Hsieh, K AF Satapathy, Sikhanda Hsieh, Kuota TI Jump conditions for Maxwell equations and their consequences SO AIP ADVANCES LA English DT Article AB We derived the jump conditions for Faraday's induction law at the interface of two contacting bodies in both Eulerian and Lagrangian descriptions. An algorithm to implement the jump conditions in the potential formulation of Maxwell equation is presented. Calculations show that the use of the correct jump conditions leads to good agreement with experimental data, whereas the use of incorrect jump conditions can lead to severe inaccuracies in the computational results. Our derivation resolves the jump condition discrepancy found in the literature and is validated with experimental results. Copyright 2013 Author(s). This article is distributed under a Creative Commons Attribution 3.0 Unported License. [http://dx.doi.org/10.1063/1.4789794] C1 [Satapathy, Sikhanda] USA, Res Lab, RDRL WMP B, Aberdeen Proving Ground, MD 21005 USA. [Hsieh, Kuota] Univ Texas Austin, Ctr Electromech, Austin, TX 78712 USA. RP Satapathy, S (reprint author), USA, Res Lab, RDRL WMP B, Aberdeen Proving Ground, MD 21005 USA. RI Satapathy, Sikhanda/L-5264-2015 NR 13 TC 0 Z9 0 U1 0 U2 6 PU AMER INST PHYSICS PI MELVILLE PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA SN 2158-3226 J9 AIP ADV JI AIP Adv. PD JAN PY 2013 VL 3 IS 1 AR 012120 DI 10.1063/1.4789794 PG 13 WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied SC Science & Technology - Other Topics; Materials Science; Physics GA 086XH UT WOS:000314722300020 ER PT J AU Cerco, CF Kim, SC Noel, MR AF Cerco, Carl F. Kim, Sung-Chan Noel, Mark R. TI Management modeling of suspended solids in the Chesapeake Bay, USA SO ESTUARINE COASTAL AND SHELF SCIENCE LA English DT Article DE estuaries; eutrophication; suspended particulate matter; light attenuation; models ID SUBMERGED AQUATIC VEGETATION; SEDIMENT-TRANSPORT; TURBIDITY MAXIMUM; WATER-QUALITY; POTOMAC RIVER; EUTROPHICATION; RESUSPENSION; COMMUNITIES; DEPOSITION; MARYLAND AB The Chesapeake Bay, USA, suffers from multiple water quality impairments including poor water clarity. A management strategy aimed at improving water clarity through reduction of nutrient and solids loads to the bay is under development. The strategy is informed through the use of the Chesapeake Bay Environmental Modeling Package. We describe herein aspects of the model devoted to suspended solids, a major contributor to poor water clarity. Our approach incorporates a dynamic model of inorganic solids into an eutrophication model, in order to account for interactions between physical and biotic factors which influence suspended solids transport and fate. Solids budgets based on the model indicate that internal production of organic solids is the largest source of suspended solids to the mainstem bay. Scenario analysis indicates that control of solids loads reduces solids concentration in the vicinity of the loading sources. Control of nutrient loads provides more widespread but lesser reductions in suspended solids. Published by Elsevier Ltd. C1 [Cerco, Carl F.; Noel, Mark R.] USA, Environm Lab, Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. [Kim, Sung-Chan] USA, Coastal & Hydraul Lab, Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. RP Cerco, CF (reprint author), USA, Environm Lab, Engineer Res & Dev Ctr, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM carl.f.cerco@usace.army.mil; sung-chan.kim@usace.army.mil; mark.r.noel@usace.army.mil FU US Army Engineer District, Baltimore; US Environmental Protection Agency Chesapeake Bay Program Office FX This study was funded by the US Army Engineer District, Baltimore, and by the US Environmental Protection Agency Chesapeake Bay Program Office. Jeff Halka, of the Maryland Department of Natural Resources - Maryland Geological Survey, led the team which computed loads from bank and marsh erosion. Scott Hardaway, of the Virginia Institute of Marine Science, provided invaluable assistance in computing bankloads in the Virginia portion of the bay. The algorithms for combining current-generated and wave-generated bottom shear stresses were developed by Courtney Harris and J. Paul Rinehimer of the Virginia Institute of Marine Science. NR 62 TC 9 Z9 9 U1 2 U2 26 PU ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD PI LONDON PA 24-28 OVAL RD, LONDON NW1 7DX, ENGLAND SN 0272-7714 J9 ESTUAR COAST SHELF S JI Estuar. Coast. Shelf Sci. PD JAN 1 PY 2013 VL 116 SI SI BP 87 EP 98 DI 10.1016/j.ecss.2012.07.009 PG 12 WC Marine & Freshwater Biology; Oceanography SC Marine & Freshwater Biology; Oceanography GA 084RM UT WOS:000314556800010 ER PT J AU Stutler, SA Cox, DM AF Stutler, Shannon A. Cox, David M. TI Evaluation of a Novel Telemetry System for Use with Group-Housed Primates in Toxicology Studies SO INTERNATIONAL JOURNAL OF TOXICOLOGY LA English DT Meeting Abstract CT 33rd Annual Meeting of the American-College-of-Toxicology CY NOV 04-07, 2012 CL FL SP Amer Coll Toxicol C1 [Stutler, Shannon A.; Cox, David M.] USA, Res Support Div, Med Res Inst Chem Def, Washington, DC USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SAGE PUBLICATIONS INC PI THOUSAND OAKS PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA SN 1091-5818 J9 INT J TOXICOL JI Int. J. Toxicol. PD JAN-FEB PY 2013 VL 32 IS 1 BP 71 EP 71 PG 1 WC Pharmacology & Pharmacy; Toxicology SC Pharmacology & Pharmacy; Toxicology GA 085BW UT WOS:000314586700045 ER PT J AU Jaligama, S Kale, VM Wilbanks, MS Perkins, EJ Meyer, SA AF Jaligama, S. Kale, V. M. Wilbanks, M. S. Perkins, E. J. Meyer, S. A. TI Early Hematological Effects of Hexahydro-1-Nitroso-3,5-Dinitro-1,3,5-Triazine (MNX), Environmental Degradation Product of RDX, Persist to Cause Delayed Myelosuppression in Rats SO INTERNATIONAL JOURNAL OF TOXICOLOGY LA English DT Meeting Abstract CT 33rd Annual Meeting of the American-College-of-Toxicology CY NOV 04-07, 2012 CL FL SP Amer Coll Toxicol C1 [Jaligama, S.; Meyer, S. A.] Univ Louisiana Monroe, Dept Toxicol, Monroe, LA 71209 USA. [Kale, V. M.] Roseman Univ Hlth Sci, Coll Pharm, S Jordan, UT 84095 USA. [Wilbanks, M. S.; Perkins, E. J.] USA, Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. RI Jaligama, Sridhar/D-5533-2015 OI Jaligama, Sridhar/0000-0001-6374-3336 NR 0 TC 0 Z9 0 U1 0 U2 2 PU SAGE PUBLICATIONS INC PI THOUSAND OAKS PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA SN 1091-5818 J9 INT J TOXICOL JI Int. J. Toxicol. PD JAN-FEB PY 2013 VL 32 IS 1 BP 75 EP 76 PG 2 WC Pharmacology & Pharmacy; Toxicology SC Pharmacology & Pharmacy; Toxicology GA 085BW UT WOS:000314586700055 ER PT J AU Jain, R Yeo, H Chopra, I AF Jain, Rohit Yeo, Hyeonsoo Chopra, Inderjit TI Investigation of Trailing-Edge Flap Gap Effects on Rotor Performance Using High-Fidelity Analysis SO JOURNAL OF AIRCRAFT LA English DT Article; Proceedings Paper CT 50th AIAA Aerospace Sciences Meeting including the New Horizons Forum and Aerospace Exposition CY JAN 09-12, 2012 CL Nashville, TN SP AIAA ID ACTIVE CONTROLS; ENHANCEMENT; AIRLOADS; DYNAMICS AB Effects of trailing-edge flap gaps on rotor performance are investigated using a high-fidelity coupled computational fluid dynamics computational structural dynamics analysis. Both integral flap (the flap is an integral part of the blade such that there are no physical gaps at the flap ends) and discrete flap (the flap is a separate entity with physical gaps in the span and chord directions) are examined on an UH-60A rotor at high-speed forward-flight conditions. A novel grid deformation scheme based on the Delaunay graph mapping is developed and implemented to allow the computational fluid dynamics modeling of the gaps with minimal distortion of mesh around the flap gap regions. This method offers an alternative to the traditional approach of modeling such configurations using overset meshes. The simulation results show that the effectiveness of the flap is minimally affected with span gaps; the penalty on rotor performance is of the order of 1% compared to the integral flap. On the other hand, the chord gaps significantly degrade the benefits of active flap on rotor performance due to the flow penetration between the upper and lower surfaces of the flap. C1 [Jain, Rohit] HyPerComp Inc, Westlake Village, CA USA. [Yeo, Hyeonsoo] USA, Ames Res Ctr, Aeroflightdynam Directorate AMRDEC, Res Dev & Engn Command, Moffett Field, CA USA. [Chopra, Inderjit] Univ Maryland, Dept Aerosp Engn, Alfred Gessow Rotorcraft Ctr, College Pk, MD 20742 USA. RP Jain, R (reprint author), HyPerComp Inc, Westlake Village, CA USA. EM rjain@merlin.arc.nasa.gov NR 24 TC 3 Z9 4 U1 0 U2 9 PU AMER INST AERONAUT ASTRONAUT PI RESTON PA 1801 ALEXANDER BELL DRIVE, STE 500, RESTON, VA 22091-4344 USA SN 0021-8669 J9 J AIRCRAFT JI J. Aircr. PD JAN-FEB PY 2013 VL 50 IS 1 BP 140 EP 151 DI 10.2514/1.C031837 PG 12 WC Engineering, Aerospace SC Engineering GA 086EQ UT WOS:000314667100014 ER PT J AU Desabrais, KJ Johari, H AF Desabrais, Kenneth J. Johari, Hamid TI Experimental Investigation of Parachute Canopies with Rectangular Parallelepiped Geometries SO JOURNAL OF AIRCRAFT LA English DT Article AB A series of wind-tunnel experiments were conducted in which the drag characteristics and inflated geometry of model parachute canopies with rectangular parallelepiped geometries (polyhedron) were examined. The model-canopy layouts were the same as cross canopies with the adjacent sides completely attached together. All models had a base dimension of 0.2 m, and aspect ratios ranged from 0.2 to 1.2. The models did not have a central vent or any other geometric porosity. The data show the inflated geometry of the canopy differs from the constructed geometry with the smallest change occurring at a constructed aspect of 0.8 and the variation becomes larger for increasing or decreasing constructed aspect ratios. The data also indicate the aerodynamic drag coefficient, based on the projected area, has a maximum value of approximately one for the constructed aspect ratio of 0.3 corresponding to an inflated aspect ratio of 0.53. The drag coefficient is less for smaller and larger aspect-ratio models. If scaled by the canopy surface area drag of the rectangular parallelepiped canopies is lower than flat circular canopy designs. These findings are consistent with the past findings on other flexible parachute canopies and rigid bluff bodies. C1 [Desabrais, Kenneth J.] USA, Natick Soldier Res Dev & Engn Ctr, Warfighter Protect & Aerial Delivery Directorate, Airdrop Technol Team, Natick, MA 01760 USA. [Johari, Hamid] Calif State Univ Northridge, Dept Mech Engn, Northridge, CA 91330 USA. RP Desabrais, KJ (reprint author), USA, Natick Soldier Res Dev & Engn Ctr, Warfighter Protect & Aerial Delivery Directorate, Airdrop Technol Team, 15 Kansas St RDNS WPA T, Natick, MA 01760 USA. NR 13 TC 0 Z9 0 U1 1 U2 11 PU AMER INST AERONAUT ASTRONAUT PI RESTON PA 1801 ALEXANDER BELL DRIVE, STE 500, RESTON, VA 22091-4344 USA SN 0021-8669 J9 J AIRCRAFT JI J. Aircr. PD JAN-FEB PY 2013 VL 50 IS 1 BP 197 EP 203 DI 10.2514/1.C031854 PG 7 WC Engineering, Aerospace SC Engineering GA 086EQ UT WOS:000314667100019 ER PT J AU Cann, JA Jahrling, PB Hensley, LE Wahl-Jensen, V AF Cann, J. A. Jahrling, P. B. Hensley, L. E. Wahl-Jensen, V. TI Comparative Pathology of Smallpox and Monkeypox in Man and Macaques SO JOURNAL OF COMPARATIVE PATHOLOGY LA English DT Article DE macaque; monkeypox; smallpox; variola ID LETHAL MONKEYPOX; MACACA-IRUS; HAEMORRHAGIC SMALLPOX; CYNOMOLGUS MONKEYS; NONHUMAN-PRIMATES; VIRUS-INFECTION; VACCINIA VIRUS; VARIOLA; POXVIRUSES; CHALLENGE AB In the three decades since the eradication of smallpox and cessation of routine vaccination, the collective memory of the devastating epidemics caused by this orthopoxvirus has waned, and the human population has become increasingly susceptible to a disease that remains high on the list of possible bioterrorism agents. Research using surrogate orthopoxviruses in their natural hosts, as well as limited variola virus research in animal models, continues worldwide; however, interpretation of findings is often limited by our relative lack of knowledge about the naturally occurring disease. For modern comparative pathologists, many of whom have no first-hand knowledge of naturally occurring smallpox, this work provides a contemporary review of this historical disease, as well as discussion of how it compares with human monkeypox and the corresponding diseases in macaques. (C) 2012 Elsevier Ltd. All rights reserved. C1 [Cann, J. A.; Jahrling, P. B.; Wahl-Jensen, V.] NIAID, Integrated Res Facil Ft Detrick, Div Clin Res, NIH, Frederick, MD USA. [Hensley, L. E.] USA, Med Res Inst Infect Dis, Frederick, MD USA. RP Cann, JA (reprint author), NIAID, Integrated Res Facil Ft Detrick, Div Clin Res, NIH, 8200 Res Plaza, Frederick, MD USA. EM cannja@niaid.nih.gov FU Battelle Memorial Institute [HHSN2722007000161]; NIAID FX The authors wish to thank J. Kuhn, D. Perry, D. Ragland and A. Johnson for thoughtful discussions and critique, and L. Bollinger for technical assistance. JAC performed this work as an employee of Charles River Laboratories and VWJ as an employee of Tunnell Consulting, Inc., both subcontractors to Battelle Memorial Institute under its prime contract HHSN2722007000161 with NIAID. NR 65 TC 9 Z9 10 U1 1 U2 14 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0021-9975 J9 J COMP PATHOL JI J. Comp. Pathol. PD JAN PY 2013 VL 148 IS 1 BP 6 EP 21 DI 10.1016/j.jcpa.2012.06.007 PG 16 WC Pathology; Veterinary Sciences SC Pathology; Veterinary Sciences GA 086HE UT WOS:000314673900003 PM 22884034 ER PT J AU Hoefinger, M Blanken, CL AF Hoefinger, Marc Blanken, Chris L. TI Flight Testing the ADS-33E Cargo Helicopter Handling Qualities Requirements Using a CH-53G SO JOURNAL OF THE AMERICAN HELICOPTER SOCIETY LA English DT Article AB Flight tests with a German Army Sikorsky CH-53G helicopter were performed to evaluate the applicability and repeatability of the U.S. Army's Aeronautical Design Standard (ADS)-33E-PRE cargo helicopter handling qualities requirements. The objectives were to corroborate earlier findings and to propose modifications if deemed necessary. The CH-53G was chosen because it is the largest helicopter operated by the German Army, and its dedicated role is cargo and troop transport. The quantitative criteria and the associated boundaries as specified in the standard were largely confirmed. Several flight test maneuvers were revised and tailored. Generally, the heights for performing the near-earth maneuvers were increased. The time/tolerances experienced were borderline desired/adequate or adequate. C1 [Hoefinger, Marc] German Aerosp Ctr DLR, Inst Flight Syst, Rotorcraft Branch, Braunschweig, Germany. [Blanken, Chris L.] USA, Flight Control & Cockpit Integrat Div, Aeroflightdynam Directorate AMRDEC, RDECOM, Moffett Field, CA USA. RP Hoefinger, M (reprint author), German Aerosp Ctr DLR, Inst Flight Syst, Rotorcraft Branch, Braunschweig, Germany. EM marc.hoefinger@dlr.de NR 32 TC 0 Z9 0 U1 1 U2 3 PU AMER HELICOPTER SOC INC PI ALEXANDRIA PA 217 N WASHINGTON ST, ALEXANDRIA, VA 22314 USA SN 0002-8711 J9 J AM HELICOPTER SOC JI J. Am. Helicopter Soc. PD JAN PY 2013 VL 58 IS 1 AR 012002 DI 10.4050/JAHS.58.012002 PG 11 WC Engineering, Aerospace SC Engineering GA 084RV UT WOS:000314557700003 ER PT J AU Ivler, CM Tischler, MB AF Ivler, Christina M. Tischler, Mark B. TI Case Studies of System Identification Modeling for Flight Control Design SO JOURNAL OF THE AMERICAN HELICOPTER SOCIETY LA English DT Article ID HELICOPTER AB Flight control design and analysis requires an accurate flight dynamics model of the bare airframe and its associated uncertainties, as well as the integrated system model (block diagrams), across the frequency range of interest. Frequency response system identification methods have proven to efficiently fulfill these modeling requirements in recent rotorcraft flight control applications. This paper presents integrated system identification methods for control law design with flight-test examples of the Fire Scout MQ-8B, S-76, and ARH-70A. The paper also looks toward how system identification could be used in new modeling challenges such as large tilt-rotors and uniquely configured unmanned aircraft. C1 [Ivler, Christina M.] USA, Aeroflightdynam Directorate AMRDEC, Res Dev & Engn Command, Moffett Field, CA USA. [Tischler, Mark B.] USA, Aeroflightdynam Directorate AMRDEC, Res Dev & Engn Command, Flight Control Grp, Moffett Field, CA USA. RP Ivler, CM (reprint author), USA, Aeroflightdynam Directorate AMRDEC, Res Dev & Engn Command, Moffett Field, CA USA. EM christina.ivler@us.army.mil NR 25 TC 0 Z9 0 U1 1 U2 14 PU AMER HELICOPTER SOC INC PI ALEXANDRIA PA 217 N WASHINGTON ST, ALEXANDRIA, VA 22314 USA SN 0002-8711 J9 J AM HELICOPTER SOC JI J. Am. Helicopter Soc. PD JAN PY 2013 VL 58 IS 1 AR 012003 DI 10.4050/JAHS.58.012003 PG 16 WC Engineering, Aerospace SC Engineering GA 084RV UT WOS:000314557700004 ER PT J AU Johnston, DT Deuster, PA Harris, WS MacRae, H Dretsch, MN AF Johnston, Daniel T. Deuster, Patricia A. Harris, William S. MacRae, Holden Dretsch, Michael N. TI Red blood cell omega-3 fatty acid levels and neurocognitive performance in deployed US Servicemembers SO NUTRITIONAL NEUROSCIENCE LA English DT Article DE Omega-3; Neurocognition; Omega-3 index; Performance; Military; Brain ID RATING DEPRESSION SCALE; TRAUMATIC BRAIN-INJURY; SLEEP QUALITY INDEX; N-3 FATTY-ACIDS; CORONARY-HEART-DISEASE; DOCOSAHEXAENOIC ACID; DIETARY-INTAKE; CONTROLLED-TRIAL; OMEGA-3 INDEX; AXONAL INJURY AB Objective: To explore the cross-sectional relationships between blood eicosapentaenoic acid + docosahexaenoic acid (HSOmega-3 Index (R)) and sleep disorders, depression, anxiety, and neurocognitive performance in Servicemembers deployed to Iraq. Methods: Servicemembers with mild-to-moderate depression by the Patient Health Questionnarie-9 from two US military camps were invited to participate in this study. A battery of validated psychosocial (Pittsburgh Sleep Quality Index, and Zung Depression, Zung Anxiety, Epworth Sleepiness, and Combat Experiences scales) and computerized neurocognitive tests were completed by each participant. Five neurocognitive domain scores were calculated - Processing Speed, Complex Attention, Reaction Time, Cognitive Flexibility (CF), and Executive Function (EF). A drop of blood was also collected on an anti-oxidant-treated filter paper card and sent for HS-Omega-3 Index (R) analysis. An analysis of variance contrast was used to test for linear trends between quartiles of the HS-Omega-3 Index (R) for both EF and CF. Results: The mean HS-Omega-3 Index (R) was 3.5 +/- 0.7% (n = 78). The HS-Omega-3 Index (R) was not significantly associated with scores for anxiety, depression, or sleep, whether assessed as continuous or dichotomous variables, but was directly associated with CF and EF (P < 0.02 and 0.01, respectively), especially in the 81% who reported poor sleep quality. In those with poor sleep quality (n = 63), EF and CF were higher (P = 0.005) in subjects with Omega-3 levels above versus below the mean. Conclusion: Optimal neurocognitive performance is essential during deployment. Our finding that EF and CF were positively related to HS-Omega-3 Index (R) suggests that improving omega-3 status through an increase in omega-3 intake may improve neurocognitive performance and confer an element of resilience to poor sleep. C1 [Johnston, Daniel T.] USA, Comprehens Soldier Fitness Performance Resilience, Headquarters Dept, Washington, DC 20310 USA. [Deuster, Patricia A.] Uniformed Serv Univ Hlth Sci, Consortium Hlth & Mil Performance, Dept Mil & Emergency Med, Bethesda, MD 20814 USA. [Harris, William S.] Univ S Dakota, Sanford Sch Med, Sioux Falls, SD 57105 USA. [Harris, William S.] OmegaQuant Analyt LLC, Sioux Falls, SD 57105 USA. [Harris, William S.] Hlth Diagnost Lab Inc, Richmond, VA USA. [MacRae, Holden] Pepperdine Univ, Div Nat Sci, Malibu, CA 90265 USA. [Dretsch, Michael N.] USA, Aeromed Res Lab USAARL, Ft Rucker, AL USA. RP Johnston, DT (reprint author), 2530 Crystal Dr,Rm 1628, Arlington, VA 22203 USA. EM Daniel.Johnston@us.army.mil RI Deuster, Patricia/G-3838-2015 OI Deuster, Patricia/0000-0002-7895-0888 NR 67 TC 24 Z9 24 U1 2 U2 17 PU MANEY PUBLISHING PI LEEDS PA STE 1C, JOSEPHS WELL, HANOVER WALK, LEEDS LS3 1AB, W YORKS, ENGLAND SN 1028-415X J9 NUTR NEUROSCI JI Nutr. Neurosci. PD JAN PY 2013 VL 16 IS 1 BP 30 EP 38 DI 10.1179/1476830512Y.0000000025 PG 9 WC Neurosciences; Nutrition & Dietetics SC Neurosciences & Neurology; Nutrition & Dietetics GA 087OL UT WOS:000314771400005 PM 22748167 ER PT J AU Sherlock, T AF Sherlock, Thomas TI It Was a Long Time Ago, and It Never Happened Anyway: Russia and the Communist Past SO RUSSIAN REVIEW LA English DT Book Review C1 [Sherlock, Thomas] US Mil Acad, West Point, NY 10996 USA. RP Sherlock, T (reprint author), US Mil Acad, West Point, NY 10996 USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0036-0341 J9 RUSS REV JI Russ. Rev. PD JAN PY 2013 VL 72 IS 1 BP 172 EP 173 PG 2 WC History SC History GA 075HL UT WOS:000313875300034 ER PT J AU Miller, CT Dawson, CN Farthing, MW Hou, TY Huang, JF Kees, CE Kelley, CT Langtangen, HP AF Miller, Cass T. Dawson, Clint N. Farthing, Matthew W. Hou, Thomas Y. Huang, Jingfang Kees, Christopher E. Kelley, C. T. Langtangen, Hans Petter TI Numerical simulation of water resources problems: Models, methods, and trends SO ADVANCES IN WATER RESOURCES LA English DT Article DE Adaptive methods; Problem solving environments; Multiscale methods; Integral methods; GPUs; Error estimation and control ID FINITE-ELEMENT METHODS; POROUS-MEDIUM SYSTEMS; DISCONTINUOUS GALERKIN METHODS; AVERAGING THEORY APPROACH; PATTERN MULTIFRONTAL METHOD; DEFERRED CORRECTION METHODS; SOLVING RICHARDS EQUATION; VARIABLY SATURATED FLOW; SPLIT-OPERATOR METHODS; LEVEL SET METHOD AB Mechanistic modeling of water resources systems is a broad field with abundant challenges. We consider classes of model formulations that are considered routine, the focus of current work, and the foundation of foreseeable work over the coming decade. These model formulations are used to assess the current and evolving state of solution algorithms, discretization methods, nonlinear and linear algebraic solution methods, computational environments, and hardware trends and implications. The goal of this work is to provide guidance to enable modelers of water resources systems to make sensible choices when developing solution methods based upon the current state of knowledge and to focus future collaborative work among water resources scientists, applied mathematicians, and computational scientists on productive areas. (C) 2012 Elsevier Ltd. All rights reserved. C1 [Miller, Cass T.] Univ N Carolina, Dept Environm Sci & Engn, Chapel Hill, NC 27599 USA. [Dawson, Clint N.] Univ Texas Austin, Austin, TX 78712 USA. [Farthing, Matthew W.; Kees, Christopher E.] USA, Coastal & Hydraul Lab, Engn Res & Dev Ctr, Vicksburg, MS 39180 USA. [Hou, Thomas Y.] CALTECH, Pasadena, CA 91125 USA. [Huang, Jingfang] Univ N Carolina, Dept Math, Chapel Hill, NC 27599 USA. [Kelley, C. T.] N Carolina State Univ, Dept Math, Raleigh, NC 27695 USA. [Langtangen, Hans Petter] Simula Res Lab, NO-1325 Lysaker, Norway. RP Miller, CT (reprint author), Univ N Carolina, Dept Environm Sci & Engn, Chapel Hill, NC 27599 USA. EM casey_miller@unc.edu; clint@ices.utexas.edu; matthew.w.farthing@usace.army.mil; hou@cms.caltech.edu; huang@email.unc.edu; chris.kees@us.army.mil; Tim_Kelley@ncsu.edu; hpl@simula.no RI Miller, Cass T./I-6613-2012 OI Miller, Cass T./0000-0001-6082-9273 FU Department of Energy [DE-SC0002163, DE-FG02-06ER25727]; National Science Foundation [CDI-0941235, DMS 0915223, DMS-0908546, DMS-0811130, CDI-0941253]; U.S. Army Corps of Engineers [W912HZ-11-P-0385]; Coastal and Hydraulics Laboratory Internal Research Investment Program; AFOSR MURI [FA9550-09-1-0613]; ARO [W911NF-11-1-0367]; Center of Excellence grant from the Research Council of Norway FX The work of CTM was supported by Department of Energy Grant DE-SC0002163 and National Science Foundation Grant CDI-0941235. The work of CND was supported by National Science Foundation Grant DMS 0915223. The work of MWF and CEK was supported by the Civil Works and Military Engineering 6.1 research programs of the U.S. Army Corps of Engineers and the Coastal and Hydraulics Laboratory Internal Research Investment Program. Permission was granted by the Chief of Engineers to publish this information. The work of TYH was supported by AFOSR MURI Grant FA9550-09-1-0613, Department of Energy Grant DE-FG02-06ER25727, and National Science Foundation Grant DMS-0908546. The work of JH was supported by NSF Grants DMS-0811130 and CDI-0941235. The work of CTK was supported by ARO Grant W911NF-11-1-0367, US Army Corps of Engineers Contract W912HZ-11-P-0385, and NSF Grant CDI-0941253. The work of HPL was supported by a Center of Excellence grant from the Research Council of Norway to the Center for Biomedical Computing at Simula Research Laboratory. NR 314 TC 17 Z9 18 U1 5 U2 58 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0309-1708 EI 1872-9657 J9 ADV WATER RESOUR JI Adv. Water Resour. PD JAN PY 2013 VL 51 BP 405 EP 437 DI 10.1016/j.advwatres.2012.05.008 PG 33 WC Water Resources SC Water Resources GA 078NN UT WOS:000314105900024 ER PT J AU Perez, JJ Flanigan, PM Brady, JJ Levis, RJ AF Perez, Johnny J. Flanigan, Paul M. Brady, John J. Levis, Robert J. TI Classification of Smokeless Powders Using Laser Electrospray Mass Spectrometry and Offline Multivariate Statistical Analysis SO ANALYTICAL CHEMISTRY LA English DT Article ID ION MOBILITY SPECTROMETRY; GUNSHOT RESIDUES; DIPHENYLAMINE STABILIZER; NITRATED DERIVATIVES; RAMAN-SPECTROSCOPY; METHYL CENTRALITE; MS METHOD; IONIZATION; GUNPOWDER; VAPORIZATION AB A direct, sensitive, and rapid method for the detection of smokeless powder components, from five different types of ammunition, is demonstrated using laser electrospray mass spectrometry (LEMS). Common components found in powder, such as ethyl centralite, methyl centralite, dibutyl phthalate, and dimethyl phthalate, are detected under atmospheric conditions without additional sample preparation. LEMS analysis of the powders revealed several new mass spectral features that have not been identified previously. Offline principal component analysis and discrimination of the LEMS mass spectral measurements resulted in perfect classification of the smokeless powder with respect to manufacturer. C1 [Perez, Johnny J.; Flanigan, Paul M.; Levis, Robert J.] Temple Univ, Dept Chem, Adv Photon Res Ctr, Philadelphia, PA 19122 USA. [Brady, John J.] USA, Res Lab, Adelphi, MD 20783 USA. RP Levis, RJ (reprint author), Temple Univ, Dept Chem, Adv Photon Res Ctr, 1901 N 13th St, Philadelphia, PA 19122 USA. EM rjlevis@temple.edu FU Office of Naval Research [N00014-10-0293]; National Science Foundation [CHE0957694] FX The work was supported by the Office of Naval Research (N00014-10-0293) and the National Science Foundation (CHE0957694). J.J.B. acknowledges the Oak Ridge Associated Universities Postdoctoral Research Program. NR 34 TC 16 Z9 16 U1 1 U2 61 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 0003-2700 EI 1520-6882 J9 ANAL CHEM JI Anal. Chem. PD JAN 1 PY 2013 VL 85 IS 1 BP 296 EP 302 DI 10.1021/ac302661k PG 7 WC Chemistry, Analytical SC Chemistry GA 065NZ UT WOS:000313156500044 PM 23215164 ER PT J AU Varela-Ortiz, W Cintron, CYL Velazquez, GI Stanton, TR AF Varela-Ortiz, Wilmel Cintron, Carmen Y. Lugo Velazquez, Gerardo I. Stanton, Terry R. TI Load testing and GPR assessment for concrete bridges on military installations SO CONSTRUCTION AND BUILDING MATERIALS LA English DT Article DE Concrete bridges; Non-destructive load testing; Ground Penetrating Radar; Strain transducers; Moving loads; Safe load-carrying capacity AB The US Army owns and maintains approximately 2000 bridges on its installations spread out in the United States and around the world. From this inventory, 67% are concrete bridges, most of which do not have design or as-built plans to effectively evaluate their condition/capacity. In addition, military vehicles have unique characteristics that are difficult to take into account when analytical analyses are performed. For these purposes, the US Army Engineer Research and Development Center has been adapting non-destructive techniques. The most promising concept explored thus far involves bridge rating through non-destructive load testing in combination with Ground Penetrating Radar (GPR) techniques. Field load testing techniques are valuable for evaluating the capacity of existing bridges and accurately characterize the structure's live-load response while GPR techniques provide valuable information regarding the internal reinforcement as well as the condition of the concrete. This article will provide a brief description as well as the results from recent evaluations performed on reinforced concrete bridges at military installations. (C) 2010 Published by Elsevier Ltd. C1 [Varela-Ortiz, Wilmel; Cintron, Carmen Y. Lugo; Velazquez, Gerardo I.; Stanton, Terry R.] USA, ERDC, Vicksburg, MS 39180 USA. RP Varela-Ortiz, W (reprint author), USA, ERDC, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM Wilmel.Varela-Ortiz@usace.army.mil; Car-men.Y.Lugo@usace.army.mil; Gerardo.I.Velazquez@usa-ce.army.mil; Terry.R.Stanton@usace.army.mil NR 9 TC 3 Z9 4 U1 1 U2 8 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0950-0618 J9 CONSTR BUILD MATER JI Constr. Build. Mater. PD JAN PY 2013 VL 38 BP 1255 EP 1269 DI 10.1016/j.conbuildmat.2010.09.044 PG 15 WC Construction & Building Technology; Engineering, Civil; Materials Science, Multidisciplinary SC Construction & Building Technology; Engineering; Materials Science GA 073UG UT WOS:000313767900141 ER PT J AU Kott, A Arnold, C AF Kott, Alexander Arnold, Curtis TI The Promises and Challenges of Continuous Monitoring and Risk Scoring SO IEEE SECURITY & PRIVACY LA English DT Editorial Material C1 [Kott, Alexander] USA, Res Lab, Network Sci Div, Washington, DC 20310 USA. [Arnold, Curtis] USA, Res Lab, Sustaining Base Network Assurance Branch, Washington, DC USA. RP Kott, A (reprint author), USA, Res Lab, Network Sci Div, Washington, DC 20310 USA. EM Alexander.Kott1@us.army.mil; Curtis.B.Arnold@us.army.mil NR 9 TC 7 Z9 8 U1 0 U2 2 PU IEEE COMPUTER SOC PI LOS ALAMITOS PA 10662 LOS VAQUEROS CIRCLE, PO BOX 3014, LOS ALAMITOS, CA 90720-1314 USA SN 1540-7993 J9 IEEE SECUR PRIV JI IEEE Secur. Priv. PD JAN-FEB PY 2013 VL 11 IS 1 BP 90 EP 93 PG 4 WC Computer Science, Information Systems; Computer Science, Software Engineering SC Computer Science GA 080QE UT WOS:000314257500017 ER PT J AU McKenna, SP Parkman, KB Perren, LJ McKenna, JR AF McKenna, Sean P. Parkman, Kevin B. Perren, Lee J. McKenna, Jason R. TI Automatic Detection of a Subsurface Wire Using an Electromagnetic Gradiometer SO IEEE TRANSACTIONS ON GEOSCIENCE AND REMOTE SENSING LA English DT Article DE Buried object detection; correlation; detection algorithms; electromagnetic induction (EMI) ID UNDERGROUND TUNNELS; FREQUENCY; CONDUCTOR; IDENTIFICATION AB A model-based correlation detection scheme is presented with the aim of detecting and localizing subsurface tunnel infrastructure in an automated fashion. Our goal is to develop a comprehensive detection technology that can be fielded and successfully used by nonexperts, while simultaneously being sufficiently robust as to be effective. Our correlation detection algorithm relies on a library of model signals that are generated using an analytical model of a thin subsurface wire in a homogeneous half-space. The wire is illuminated using an active transmitter source (12, 20, or 200 kHz), and its response is sensed using a man-portable electromagnetic gradiometer (EMG) system. The performance of the detector is assessed using synthetic data and receiver operating characteristic (ROC) analysis as well as experimental data collected during a field test. Preliminary ROC results indicate that at sufficient signal-to-noise ratio, the detector can achieve detection probabilities greater than 0.9 with corresponding false alarm rates of less than one every 1000 m. Results from the field tests revealed that the responses from the EMG can be used to detect and localize (to within 0.5 m in the horizontal) a wire target down to a depth of at least 7 m. We believe the EMG system and correlation detector combine to form a promising technology for detecting tunnel infrastructure that can be used by experts and, more importantly, nonexperts as well. C1 [McKenna, Sean P.] USN, Postgrad Sch, Monterey, CA 93943 USA. [Parkman, Kevin B.] USA, Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. [Perren, Lee J.] Bevilacqua Res Corp, Huntsville, AL 35805 USA. [McKenna, Jason R.] USA, Engineer Res & Dev Ctr, Topog Engn Ctr, Alexandria, VA 22315 USA. RP McKenna, SP (reprint author), USN, Postgrad Sch, Monterey, CA 93943 USA. EM spmckenn@nps.edu; Kevin.B.Parkman@usace.army.mil; Lee.J.Perren@usace.army.mil; jason.r.mckenna@usace.army.mil FU U.S. Army Engineer Research and Development Center under the Rapid Reaction Tunnel Detection Program FX Funding for this research was provided by the U.S. Army Engineer Research and Development Center under the Rapid Reaction Tunnel Detection Program. The Director, Geotechnical and Structures Laboratory, U.S. Army Engineer Research and Development Center granted permission to publish. NR 26 TC 2 Z9 2 U1 1 U2 17 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0196-2892 J9 IEEE T GEOSCI REMOTE JI IEEE Trans. Geosci. Remote Sensing PD JAN PY 2013 VL 51 IS 1 BP 132 EP 139 DI 10.1109/TGRS.2012.2201162 PN 1 PG 8 WC Geochemistry & Geophysics; Engineering, Electrical & Electronic; Remote Sensing; Imaging Science & Photographic Technology SC Geochemistry & Geophysics; Engineering; Remote Sensing; Imaging Science & Photographic Technology GA 076NR UT WOS:000313963700015 ER PT J AU Chen, Y Nasrabadi, NM Tran, TD AF Chen, Yi Nasrabadi, Nasser M. Tran, Trac D. TI Hyperspectral Image Classification via Kernel Sparse Representation SO IEEE TRANSACTIONS ON GEOSCIENCE AND REMOTE SENSING LA English DT Article DE Classification; hyperspectral imagery; joint sparsity model; kernel methods; sparse representation ID MULTINOMIAL LOGISTIC-REGRESSION; REMOTE-SENSING IMAGES; MATCHING PURSUIT; RECOGNITION; ALGORITHMS; MACHINES; SVM AB In this paper, a novel nonlinear technique for hyperspectral image (HSI) classification is proposed. Our approach relies on sparsely representing a test sample in terms of all of the training samples in a feature space induced by a kernel function. For each test pixel in the feature space, a sparse representation vector is obtained by decomposing the test pixel over a training dictionary, also in the same feature space, by using a kernel-based greedy pursuit algorithm. The recovered sparse representation vector is then used directly to determine the class label of the test pixel. Projecting the samples into a high-dimensional feature space and kernelizing the sparse representation improve the data separability between different classes, providing a higher classification accuracy compared to the more conventional linear sparsity-based classification algorithms. Moreover, the spatial coherency across neighboring pixels is also incorporated through a kernelized joint sparsity model, where all of the pixels within a small neighborhood are jointly represented in the feature space by selecting a few common training samples. Kernel greedy optimization algorithms are suggested in this paper to solve the kernel versions of the single-pixel and multi-pixel joint sparsity-based recovery problems. Experimental results on several HSIs show that the proposed technique outperforms the linear sparsity-based classification technique, as well as the classical support vector machines and sparse kernel logistic regression classifiers. C1 [Chen, Yi; Tran, Trac D.] Johns Hopkins Univ, Dept Elect & Comp Engn, Baltimore, MD 21218 USA. [Nasrabadi, Nasser M.] USA, Res Lab, Adelphi, MD 20783 USA. RP Chen, Y (reprint author), Johns Hopkins Univ, Dept Elect & Comp Engn, Baltimore, MD 21218 USA. EM ychen98@jhu.edu; nnasraba@arl.army.mil; trac@jhu.edu FU National Science Foundation [CCF-1117545, CCF-0728893]; Army Research Office [58110-MA-II, 60219-MA]; Office of Naval Research [N102-183-0208] FX Manuscript received August 13, 2011; revised December 23, 2011 and March 22, 2012; accepted April 18, 2012. Date of publication July 10, 2012; date of current version December 19, 2012. This work was supported in part by the National Science Foundation under Grants CCF-1117545 and CCF-0728893, the Army Research Office under Grant 58110-MA-II and Grant 60219-MA, and the Office of Naval Research under Grant N102-183-0208. NR 44 TC 146 Z9 161 U1 10 U2 95 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0196-2892 J9 IEEE T GEOSCI REMOTE JI IEEE Trans. Geosci. Remote Sensing PD JAN PY 2013 VL 51 IS 1 BP 217 EP 231 DI 10.1109/TGRS.2012.2201730 PN 1 PG 15 WC Geochemistry & Geophysics; Engineering, Electrical & Electronic; Remote Sensing; Imaging Science & Photographic Technology SC Geochemistry & Geophysics; Engineering; Remote Sensing; Imaging Science & Photographic Technology GA 076NR UT WOS:000313963700022 ER PT J AU Garijo, A Marotta, SM Russell, ED AF Garijo, Antonio Marotta, Sebastian M. Russell, Elizabeth D. TI Singular perturbations in the quadratic family with multiple poles SO JOURNAL OF DIFFERENCE EQUATIONS AND APPLICATIONS LA English DT Article DE Complex dynamical systems; dynamics of rational maps; topology; combinatorics ID RATIONAL MAPS; JULIA SETS AB We consider the quadratic family of complex maps given by , where c is the centre of a hyperbolic component in the Mandelbrot set. Then, we introduce a singular perturbation on the corresponding bounded super-attracting cycle by adding one pole to each point in the cycle. When c = - 1, the Julia set of q - 1 is the well-known basilica and the perturbed map is given by , where are integers, and ? is a complex parameter such that |?| is very small. We focus on the topological characteristics of the Julia and Fatou sets of f ? that arise when the parameter ? becomes non-zero. We give sufficient conditions on the order of the poles so that for small ?, the Julia sets consist of the union of homeomorphic copies of the unperturbed Julia set, countably many Cantor sets of concentric closed curves, and Cantor sets of point components that accumulate on them. C1 [Garijo, Antonio] Univ Rovira & Virgili, Dep Eng Informat & Matemat, Tarragona 43007, Spain. [Marotta, Sebastian M.] Univ Pacific, Dept Math, Stockton, CA 95211 USA. [Russell, Elizabeth D.] US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. RP Russell, ED (reprint author), US Mil Acad, Dept Math Sci, West Point, NY 10996 USA. EM antonio.garijo@urv.cat; smarotta@pacific.edu; elizabeth.russell@usma.edu RI Garijo, Antonio/L-8367-2014 OI Garijo, Antonio/0000-0002-1503-7514 FU Catalan grant [2009SGR-792]; Spanish grant [MTM-2008-01486 Consolider]; European Community [035651-1-2-CODY] FX The first author is partially supported by the Catalan grant 2009SGR-792, by the Spanish grant MTM-2008-01486 Consolider (including FEDER contribution) and by the European Community through the project 035651-1-2-CODY. We would also like to thank the referee for many helpful comments and suggestions which greatly improved the presentation of this article. NR 12 TC 0 Z9 0 U1 0 U2 0 PU TAYLOR & FRANCIS LTD PI ABINGDON PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND SN 1023-6198 J9 J DIFFER EQU APPL JI J. Differ. Equ. Appl. PD JAN 1 PY 2013 VL 19 IS 1 BP 124 EP 145 DI 10.1080/10236198.2011.630668 PG 22 WC Mathematics, Applied SC Mathematics GA 072AG UT WOS:000313639600009 ER PT J AU Cesur, R Sabia, JJ Tekin, E AF Cesur, Resul Sabia, Joseph J. Tekin, Erdal TI The psychological costs of war: Military combat and mental health SO JOURNAL OF HEALTH ECONOMICS LA English DT Article DE Military combat; Depression; Post-traumatic stress disorder; Suicide ID POSTTRAUMATIC-STRESS-DISORDER; VIETNAM VETERANS; SUICIDE ATTEMPT; ARMED-FORCES; US VETERANS; GULF-WAR; DEPLOYMENT; SERVICE; AFGHANISTAN; DEPRESSION AB We exploit plausibly exogenous variation in overseas deployment assignment to estimate the effect of combat exposure on psychological well-being. Controlling for pre-deployment mental health, we find that active-duty soldiers deployed to combat zones are more likely to suffer from post-traumatic stress disorder (PTSD) than their counterparts deployed outside the United States in non-combat zones. Among those deployed to combat zones, those deployed to locales where they engage in enemy firefight or witness allied or civilian deaths are at an increased risk for suicidal ideation and PTSD relative to their active-duty counterparts deployed to combat zones without enemy firefight. (C) 2012 Elsevier B.V. All rights reserved. C1 [Cesur, Resul] Univ Connecticut, Dept Finance, Storrs, CT 06269 USA. [Sabia, Joseph J.] San Diego State Univ, San Diego, CA 92182 USA. [Sabia, Joseph J.] US Mil Acad, Dept Econ, San Diego, CA 92182 USA. [Tekin, Erdal] Georgia State Univ, IZA, Atlanta, GA 30303 USA. [Tekin, Erdal] Andrew Young Sch Policy Studies, Dept Econ, NBER, Atlanta, GA USA. RP Tekin, E (reprint author), Georgia State Univ, IZA, Atlanta, GA 30303 USA. EM cesur@business.uconn.edu; jsabia@mail.sdsu.edu; tekin@gsu.edu FU National Institute of Child Health and Human Development [P01-HD31921] FX The authors thank John Z. Smith, David Lyle, Daniel I. Rees, Solomon W. Polachek, Jeffrey S. DeSimone, and participants at the 2012 American Economic Association meetings, the 2011 International Health Economics Association World Congress, the 2011 European Society for Population Economics meetings, the 2011 Association for Public Policy Analysis and Management, the University of Connecticut, and the 2010 Southern Economic Association meetings for useful comments and suggestions on an earlier draft of this paper. Thanks also to Whitney Dudley for excellent research assistance. This research uses data from Add Health, a program project designed by J. Richard Udry, Peter S. Bearman, and Kathleen Mullan Harris, and funded by a grant P01-HD31921 from the National Institute of Child Health and Human Development, with cooperative funding from 17 other agencies. Special acknowledgment is due Ronald R. Rindfuss and Barbara Entwisle for assistance in the original design. Persons interested in obtaining data files from Add Health should contact Add Health, Carolina Population Center, 123 W. Franklin Street, Chapel Hill, NC 27516-2524, United States (http://www.cpc.unc.edu/addhealth/contract.html). NR 67 TC 25 Z9 25 U1 3 U2 40 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0167-6296 J9 J HEALTH ECON JI J. Health Econ. PD JAN PY 2013 VL 32 IS 1 BP 51 EP 65 DI 10.1016/j.jhealeco.2012.09.001 PG 15 WC Economics; Health Care Sciences & Services; Health Policy & Services SC Business & Economics; Health Care Sciences & Services GA 082HZ UT WOS:000314384200005 PM 23220456 ER PT J AU Gibby, B AF Gibby, Bryan TI "The Best Little Army" SO JOURNAL OF MILITARY HISTORY LA English DT Article AB Historians have generally assumed that the poor showing made by the South Korean military in the opening stages of the Korean War was inevitable and have attributed much of the blame for this to the U.S. Army advisory group in Korea, known colloquially as "KMAG." However, a closer look at the documentary evidence shows that KMAG was keenly aware of the South Korean military's shortcomings and was doing its best to correct them as war came. Although KMAG's program to improve the equipment and leadership of the South Korean military and to focus its efforts on conventional defense, as opposed to counterinsurgency activities, proved insufficient to stop the North Korean invasion, U.S. advisors did succeed in forging an infrastructure that allowed the South Korean army to survive and eventually to grow into a potent military force during the war. C1 [Gibby, Bryan] USA, Ft Gordon, GA USA. [Gibby, Bryan] US Mil Acad, West Point, NY USA. RP Gibby, B (reprint author), USA, Ft Gordon, GA USA. NR 31 TC 0 Z9 0 U1 0 U2 2 PU SOC MILITARY HISTORY PI LEXINGTON PA C/O VIRGINIA MILITARY INST, GEORGE C MARSHALL LIBRARY, LEXINGTON, VA 24450-1600 USA SN 0899-3718 J9 J MILITARY HIST JI J. Mil. Hist. PD JAN PY 2013 VL 77 IS 1 BP 173 EP 201 PG 29 WC History SC History GA 069VX UT WOS:000313466300007 ER PT J AU Daddis, GA AF Daddis, Gregory A. TI Eating Soup with a Spoon: The U.S. Army as a "Learning Organization" in the Vietnam War SO JOURNAL OF MILITARY HISTORY LA English DT Article AB Standard Vietnam War narratives often argue that the U.S. Army lost the war because it failed to learn and adapt to the conditions of an unconventional conflict. Based on a reappraisal of learning processes rather than on the outcome of the war, this essay argues that as an organization, the U.S. Army did learn and adapt in Vietnam; however, that learning was not sufficient, in itself, to preserve a South Vietnam in the throes of a powerful nationalist upheaval. A reexamination of the Army's strategic approach, operational experiences, and organizational changes reveals that significant learning did occur during the Vietnam War despite the conflict's final result. C1 US Mil Acad, West Point, NY 10996 USA. RP Daddis, GA (reprint author), US Mil Acad, West Point, NY 10996 USA. NR 82 TC 2 Z9 2 U1 0 U2 5 PU SOC MILITARY HISTORY PI LEXINGTON PA C/O VIRGINIA MILITARY INST, GEORGE C MARSHALL LIBRARY, LEXINGTON, VA 24450-1600 USA SN 0899-3718 J9 J MILITARY HIST JI J. Mil. Hist. PD JAN PY 2013 VL 77 IS 1 BP 229 EP 254 PG 26 WC History SC History GA 069VX UT WOS:000313466300009 ER PT J AU Gill, JH AF Gill, John H. TI Crossed Swords: Pakistan, Its Army and the Wars Within SO JOURNAL OF MILITARY HISTORY LA English DT Book Review C1 [Gill, John H.] Near ES Asia Ctr Strateg Studies, Washington, DC USA. [Gill, John H.] USA, S Asia Foreign Area, Washington, DC USA. RP Gill, JH (reprint author), Near ES Asia Ctr Strateg Studies, Washington, DC USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU SOC MILITARY HISTORY PI LEXINGTON PA C/O VIRGINIA MILITARY INST, GEORGE C MARSHALL LIBRARY, LEXINGTON, VA 24450-1600 USA SN 0899-3718 J9 J MILITARY HIST JI J. Mil. Hist. PD JAN PY 2013 VL 77 IS 1 BP 294 EP 298 PG 5 WC History SC History GA 069VX UT WOS:000313466300017 ER PT J AU Gill, JH AF Gill, John H. TI Military Inc.: Inside Pakistan's Military Economy SO JOURNAL OF MILITARY HISTORY LA English DT Book Review C1 [Gill, John H.] Near ES Asia Ctr Strateg Studies, Washington, DC USA. [Gill, John H.] USA, S Asia Foreign Area, Washington, DC USA. RP Gill, JH (reprint author), Near ES Asia Ctr Strateg Studies, Washington, DC USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU SOC MILITARY HISTORY PI LEXINGTON PA C/O VIRGINIA MILITARY INST, GEORGE C MARSHALL LIBRARY, LEXINGTON, VA 24450-1600 USA SN 0899-3718 J9 J MILITARY HIST JI J. Mil. Hist. PD JAN PY 2013 VL 77 IS 1 BP 294 EP 298 PG 5 WC History SC History GA 069VX UT WOS:000313466300016 ER PT J AU Gill, JH AF Gill, John H. TI Inside the Pakistan Army: A Woman's Experience on the Frontline of the War on Terror SO JOURNAL OF MILITARY HISTORY LA English DT Book Review C1 [Gill, John H.] Near ES Asia Ctr Strateg Studies, Washington, DC USA. [Gill, John H.] USA, S Asia Foreign Area, Washington, DC USA. RP Gill, JH (reprint author), Near ES Asia Ctr Strateg Studies, Washington, DC USA. NR 1 TC 0 Z9 0 U1 0 U2 1 PU SOC MILITARY HISTORY PI LEXINGTON PA C/O VIRGINIA MILITARY INST, GEORGE C MARSHALL LIBRARY, LEXINGTON, VA 24450-1600 USA SN 0899-3718 J9 J MILITARY HIST JI J. Mil. Hist. PD JAN PY 2013 VL 77 IS 1 BP 294 EP 298 PG 5 WC History SC History GA 069VX UT WOS:000313466300015 ER PT J AU Gill, JH AF Gill, John H. TI Wars, Coups & Terror: Pakistan's Army in Years of Turmoil SO JOURNAL OF MILITARY HISTORY LA English DT Book Review C1 [Gill, John H.] Near ES Asia Ctr Strateg Studies, Washington, DC USA. [Gill, John H.] USA, S Asia Foreign Area, Washington, DC USA. RP Gill, JH (reprint author), Near ES Asia Ctr Strateg Studies, Washington, DC USA. NR 1 TC 0 Z9 0 U1 0 U2 1 PU SOC MILITARY HISTORY PI LEXINGTON PA C/O VIRGINIA MILITARY INST, GEORGE C MARSHALL LIBRARY, LEXINGTON, VA 24450-1600 USA SN 0899-3718 J9 J MILITARY HIST JI J. Mil. Hist. PD JAN PY 2013 VL 77 IS 1 BP 294 EP 298 PG 5 WC History SC History GA 069VX UT WOS:000313466300013 ER PT J AU Gill, JH AF Gill, John H. TI A History of the Pakistan Army: Wars and Insurrections, 3rd edition SO JOURNAL OF MILITARY HISTORY LA English DT Book Review C1 [Gill, John H.] Near ES Asia Ctr Strateg Studies, Washington, DC USA. [Gill, John H.] USA, S Asia Foreign Area, Washington, DC USA. RP Gill, JH (reprint author), Near ES Asia Ctr Strateg Studies, Washington, DC USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU SOC MILITARY HISTORY PI LEXINGTON PA C/O VIRGINIA MILITARY INST, GEORGE C MARSHALL LIBRARY, LEXINGTON, VA 24450-1600 USA SN 0899-3718 J9 J MILITARY HIST JI J. Mil. Hist. PD JAN PY 2013 VL 77 IS 1 BP 294 EP 298 PG 5 WC History SC History GA 069VX UT WOS:000313466300014 ER PT J AU Neiberg, M AF Neiberg, Michael TI Winning and Losing on the Western Front: The British Third Army and the Defeat of Germany in 1918 SO JOURNAL OF MILITARY HISTORY LA English DT Book Review C1 [Neiberg, Michael] USA, War Coll, Carlisle, PA 17013 USA. RP Neiberg, M (reprint author), USA, War Coll, Carlisle, PA 17013 USA. NR 1 TC 0 Z9 0 U1 0 U2 1 PU SOC MILITARY HISTORY PI LEXINGTON PA C/O VIRGINIA MILITARY INST, GEORGE C MARSHALL LIBRARY, LEXINGTON, VA 24450-1600 USA SN 0899-3718 J9 J MILITARY HIST JI J. Mil. Hist. PD JAN PY 2013 VL 77 IS 1 BP 364 EP 365 PG 2 WC History SC History GA 069VX UT WOS:000313466300060 ER PT J AU Bruscino, T AF Bruscino, Thomas TI The School of Hard Knocks: Combat Leadership in the American Expeditionary Forces SO JOURNAL OF MILITARY HISTORY LA English DT Book Review C1 [Bruscino, Thomas] USA, Sch Adv Mil Studies, Ft Leavenworth, KS 66027 USA. RP Bruscino, T (reprint author), USA, Sch Adv Mil Studies, Ft Leavenworth, KS 66027 USA. NR 1 TC 0 Z9 0 U1 0 U2 1 PU SOC MILITARY HISTORY PI LEXINGTON PA C/O VIRGINIA MILITARY INST, GEORGE C MARSHALL LIBRARY, LEXINGTON, VA 24450-1600 USA SN 0899-3718 J9 J MILITARY HIST JI J. Mil. Hist. PD JAN PY 2013 VL 77 IS 1 BP 365 EP 367 PG 3 WC History SC History GA 069VX UT WOS:000313466300061 ER PT J AU Kalic, SN AF Kalic, Sean N. TI On the Edge of the Cold War: American Diplomats and Spies in Postwar Prague SO JOURNAL OF MILITARY HISTORY LA English DT Book Review C1 [Kalic, Sean N.] USA, Command & Gen Staff Coll, Ft Leavenworth, KS 66027 USA. RP Kalic, SN (reprint author), USA, Command & Gen Staff Coll, Ft Leavenworth, KS 66027 USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU SOC MILITARY HISTORY PI LEXINGTON PA C/O VIRGINIA MILITARY INST, GEORGE C MARSHALL LIBRARY, LEXINGTON, VA 24450-1600 USA SN 0899-3718 J9 J MILITARY HIST JI J. Mil. Hist. PD JAN PY 2013 VL 77 IS 1 BP 385 EP 386 PG 2 WC History SC History GA 069VX UT WOS:000313466300074 ER PT J AU Beers, W AF Beers, Wynne TI Algeria: France's Undeclared War SO JOURNAL OF MILITARY HISTORY LA English DT Book Review C1 [Beers, Wynne] US Mil Acad, West Point, NY 10996 USA. RP Beers, W (reprint author), US Mil Acad, West Point, NY 10996 USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU SOC MILITARY HISTORY PI LEXINGTON PA C/O VIRGINIA MILITARY INST, GEORGE C MARSHALL LIBRARY, LEXINGTON, VA 24450-1600 USA SN 0899-3718 J9 J MILITARY HIST JI J. Mil. Hist. PD JAN PY 2013 VL 77 IS 1 BP 391 EP 392 PG 2 WC History SC History GA 069VX UT WOS:000313466300078 ER PT J AU Lynch, CM Leandry, LA Matheny, RW AF Lynch, Christine M. Leandry, Luis A. Matheny, Ronald W., Jr. TI Lysophosphatidic acid-stimulated phosphorylation of PKD2 is mediated by PI3K p110 beta and PKC delta in myoblasts SO JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION LA English DT Article DE GPCR; signal transduction; skeletal muscle ID PROTEIN-KINASE-D; ACTIVATION LOOP SER(744); PHOSPHATIDYLINOSITOL 3-KINASE BETA; D-DEPENDENT ACTIVATION; SKELETAL-MUSCLE CELLS; PHOSPHOINOSITIDE 3-KINASE; MYOGENIC DIFFERENTIATION; CATALYTIC ACTIVATION; SIGNAL-TRANSDUCTION; IN-VIVO AB Context: G-protein coupled receptor (GPCR) signaling in skeletal muscle is incompletely understood; in particular, the signaling pathways that regulate GPCR-mediated signaling in skeletal muscle are only beginning to be established. Lysophosphatidic acid (LPA) is a GPCR agonist that has previously been shown to activate protein kinase D (PKD) in non-muscle cells; however, whether PKD is activated in response to LPA in skeletal muscle myoblasts, and the identities of signaling intermediates that regulate this activation, have not been defined. Objective: To determine whether PKD is activated in response to LPA administration in myoblasts, and to define the signaling pathways that mediate LPA-stimulated PKD phosphorylation. Methods: C2C12 myoblasts were treated with LPA and signaling pathways examined by means of Western immunoblotting and real-time PCR (RT-PCR). Pharmacological inhibition and RNA-interference were used to target specific molecules to determine their involvement in LPA-induced PKD phosphorylation. Results: Treatment of myoblasts with exogenous LPA revealed that PI3K p110 beta mediated PKD phosphorylation at Ser 748 and at Ser 916 through kinase-dependent and kinase-independent mechanisms. Loss of PKC delta, but not the loss of PKC alpha, prevented LPA-induced PKD phosphorylation. The PKD isoform responsive to LPA treatment was identified as PKD2. Conclusion: These results indicate that LPA-stimulated PKD2 phosphorylation requires PKC delta and non-catalytic actions of PI3K p110 beta, and provide new information with respect to GPCR-mediated signal transduction in myoblasts. C1 [Lynch, Christine M.; Leandry, Luis A.; Matheny, Ronald W., Jr.] USA, Environm Med Res Inst, Mil Performance Div, Natick, MA 01760 USA. RP Matheny, RW (reprint author), USA, Environm Med Res Inst, Mil Performance Div, 15 Kansas St,Bldg 42, Natick, MA 01760 USA. EM Ronald.matheny@us.army.mil FU US Army Research Institute of Environmental Medicine FX This work was supported by an appointment to the Postgraduate Research Participation Program at the US Army Research Institute of Environmental Medicine administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the US Department of Energy and USAMRMC (C. M. Lynch). NR 51 TC 3 Z9 4 U1 0 U2 4 PU INFORMA HEALTHCARE PI LONDON PA TELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLAND SN 1079-9893 J9 J RECEPT SIG TRANSD JI J. Recept. Signal Transduct. PY 2013 VL 33 IS 1 BP 41 EP 48 DI 10.3109/10799893.2012.752005 PG 8 WC Biochemistry & Molecular Biology; Cell Biology SC Biochemistry & Molecular Biology; Cell Biology GA 080UM UT WOS:000314269400006 PM 23252604 ER PT J AU Baker, JL Havas, KA Miller, LA Lacy, WA Schlanser, J AF Baker, Janice L. Havas, Karyn A. Miller, Laura A. Lacy, Ward. A. Schlanser, Justin TI Gunshot wounds in military working dogs in Operation Enduring Freedom and Operation Iraqi Freedom: 29 cases (2003-2009) SO JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE LA English DT Article DE ballistic wound; combat injuries; penetrating injury; trauma ID TRAUMA; RESUSCITATION; MANAGEMENT; DEATH AB Objective To describe the patient population, injuries, and treatment received on the battlefield, and ultimate outcome of U.S. military working dogs that incurred gunshot wound (GSW) injury in Operation Enduring Freedom (Afghanistan) or Operation Iraqi Freedom (Iraq). Design Retrospective study between January 2003 and December 2009. Animals Twenty-nine military working dogs from the U.S. military with confirmed GSW injuries incurred in combat in Operation Enduring Freedom or Operation Iraqi Freedom. Interventions None. Measurements and Main Results Clinical data from battlefield treatment, which includes care from the point of injury through arrival to, but not including, a designated veterinary treatment facility. Twenty-nine dogs were injured between 2003 and 2009. All but one of the injuries were from high caliber, high velocity weapons. Of the 29 injured dogs, 11 survived the injuries and 18 died (38% survival rate). Of the dogs that died, all but 1 died from catastrophic nonsurvivable injuries before treatment or evacuation could be instituted. The thorax was the most common site of injury (50%) followed by extremity wounds (46%). The leading cause of death from GSWs was from thoracic wounds, followed by head wounds. Dogs with extremity wounds as their only injury were most likely to survive, and dogs with multiple injuries were least likely to survive. All surviving dogs received treatment at the point of injury by military medics and dog handlers consistent with Tactical Combat Casualty Care guidelines for combat injuries in human service members. Of the 11 that survived, all dogs returned to full duty with subsequent deployment to combat zones. Location of wounds and injury severity at the time of presentation to veterinary care was not correlated with length of time until return to duty. C1 [Baker, Janice L.; Lacy, Ward. A.] Joint Special Operat Command, Ft Bragg, NC USA. [Miller, Laura A.] USA, Special Operat Command, Ft Bragg, NC USA. [Havas, Karyn A.] US Army Vet Corps, Ft Collins, CO USA. RP Baker, JL (reprint author), 8221 Peridot Dr 301, Mclean, VA 22102 USA. EM jbaker@vettacgroup.com NR 24 TC 4 Z9 4 U1 1 U2 23 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 1479-3261 J9 J VET EMERG CRIT CAR JI J. Vet. Emerg. Crit. Care PD JAN-FEB PY 2013 VL 23 IS 1 BP 47 EP 52 DI 10.1111/j.1476-4431.2012.00823.x PG 6 WC Veterinary Sciences SC Veterinary Sciences GA 079NE UT WOS:000314176500007 PM 23356705 ER PT J AU Burgess, E AF Burgess, Edwin TI Terrorist Attacks on American Soil: From the Civil War to the Present SO LIBRARY JOURNAL LA English DT Book Review C1 [Burgess, Edwin] USA, Combined Arms Res Lib, Ft Leavenworth, KS USA. RP Burgess, E (reprint author), USA, Combined Arms Res Lib, Ft Leavenworth, KS USA. NR 1 TC 0 Z9 0 U1 0 U2 1 PU REED BUSINESS INFORMATION PI NEW YORK PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010 USA SN 0363-0277 J9 LIBR J JI Libr. J. PD JAN PY 2013 VL 138 IS 1 BP 98 EP 98 PG 1 WC Information Science & Library Science SC Information Science & Library Science GA 067RF UT WOS:000313312100152 ER PT J AU Filho, IT Torres, LN Sondeen, JL Polykratis, IA Dubick, MA AF Torres Filho, Ivo Torres, Luciana N. Sondeen, Jill L. Polykratis, I. Amy Dubick, Michael A. TI In vivo evaluation of venular glycocalyx during hemorrhagic shock in rats using intravital microscopy SO MICROVASCULAR RESEARCH LA English DT Article ID ENDOTHELIAL SURFACE-LAYER; MICROCIRCULATION; DEGRADATION; HYPOTENSION; ISCHEMIA; CAPILLARIES; CREMASTER; INFLAMMATION; VELOCIMETER; LEUKOCYTES AB Hemorrhage is responsible for a large percentage of trauma-related deaths but the mechanisms underlying tissue ischemia are complex and not well understood. Despite the evidence linking glycocalyx degradation and hemorrhagic shock, there is no direct data obtained in vivo showing glycocalyx thickness reduction in skeletal muscle venules after hemorrhage. We hypothesize that damage to the endothelial glycocalyx is a key element in hemorrhage pathophysiology and tested the hypothesis that hemorrhage causes glycocalyx degradation in cremaster muscle microvessels. We utilized intravital microscopy to estimate glycocalyx thickness in 48 microvessels while other microvascular parameters were measured using non-invasive techniques. Systemic physiological parameters and blood chemistry were simultaneously collected. We studied 27 post-capillary venules (<16 mu m diameter) of 8 anesthetized rats subjected to hemorrhage (40% of total blood volume). Six control rats were equally instrumented but not bled. Dextrans of different molecular weights labeled with FITC or Texas Red were injected. Glycocalyx thickness was estimated from the widths of the fluorescence columns and from anatomical diameter. While control rats did not show remarkable responses, a statistically significant decrease of about 59% in glycocalyx thickness was measured in venules after hemorrhagic shock. Venular glycocalyx thickness and local blood flow changes were correlated: venules with the greatest flow reductions showed the largest decreases in glycocalyx. These changes may have a significant impact in shock pathophysiology. Intravital microscopy and integrated systems such as the one described here may be important tools to identify mechanisms by which resuscitation fluids may improve tissue recovery and outcome following hemorrhage. (C) 2012 Elsevier Inc. All rights reserved. C1 [Torres Filho, Ivo; Torres, Luciana N.; Sondeen, Jill L.; Polykratis, I. Amy; Dubick, Michael A.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. RP Filho, IT (reprint author), USA, Inst Surg Res, 3698 Chambers Pass,BHT 2,Room 282-2, Ft Sam Houston, TX 78234 USA. EM ivo.p.torres.ctr@us.army.mil FU US Army Combat Casualty Care Research Program FX The authors would like to thank M. Dale Prince, Daniel Darlington, Rodolfo DeGuzman, and Gary Muniz for their help during various phases of the study, James Aden for his help on statistical analysis, and Guy Drew (in memoriam) for his help with the computerized physiological data acquisition system. This study was supported in part by the US Army Combat Casualty Care Research Program, and was performed while the author Luciana Torres held a National Research Council Senior Research Associateship at the US Army Institute of Surgical Research and Ivo Torres Filho was employed by Premier Consulting 82 Management Services, Inc. and by Universidade do Estado do Rio de Janeiro (UERJ). NR 39 TC 15 Z9 15 U1 2 U2 7 PU ACADEMIC PRESS INC ELSEVIER SCIENCE PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA SN 0026-2862 J9 MICROVASC RES JI Microvasc. Res. PD JAN PY 2013 VL 85 BP 128 EP 133 DI 10.1016/j.mvr.2012.11.005 PG 6 WC Peripheral Vascular Disease SC Cardiovascular System & Cardiology GA 081JV UT WOS:000314318800018 ER PT J AU Wu, HC Tsao, CY Quan, DN Cheng, Y Servinsky, MD Carter, KK Jee, KJ Terrell, JL Zargar, A Rubloff, GW Payne, GF Valdes, JJ Bentley, WE AF Wu, Hsuan-Chen Tsao, Chen-Yu Quan, David N. Cheng, Yi Servinsky, Matthew D. Carter, Karen K. Jee, Kathleen J. Terrell, Jessica L. Zargar, Amin Rubloff, Gary W. Payne, Gregory F. Valdes, James J. Bentley, William E. TI Autonomous bacterial localization and gene expression based on nearby cell receptor density SO MOLECULAR SYSTEMS BIOLOGY LA English DT Article DE cancer; EGFR; Escherichia coli; quorum sensing; synthetic biology ID ESCHERICHIA-COLI; CANCER-THERAPY; PHENOTYPIC IMPROVEMENT; PROTEIN; OSCILLATOR; COMMUNICATION; TOLERANCE; MICROBES; GROWTH; ACID AB Escherichia coli were genetically modified to enable programmed motility, sensing, and actuation based on the density of features on nearby surfaces. Then, based on calculated feature density, these cells expressed marker proteins to indicate phenotypic response. Specifically, site-specific synthesis of bacterial quorum sensing autoinducer-2 (AI-2) is used to initiate and recruit motile cells. In our model system, we rewired E. coli's AI-2 signaling pathway to direct bacteria to a squamous cancer cell line of head and neck (SCCHN), where they initiate synthesis of a reporter (drug surrogate) based on a threshold density of epidermal growth factor receptor (EGFR). This represents a newtype of controller for targeted drug delivery as actuation (synthesis and delivery) depends on a receptor density marking the diseased cell. The ability to survey local surfaces and initiate gene expression based on feature density represents a new area-based switch in synthetic biology that will find use beyond the proposed cancer model here. Molecular Systems Biology 9: 636; published online 22 January 2013; doi:10.1038/msb.2012.71 C1 [Wu, Hsuan-Chen; Tsao, Chen-Yu; Quan, David N.; Jee, Kathleen J.; Terrell, Jessica L.; Payne, Gregory F.; Bentley, William E.] Univ Maryland, Fischell Dept Bioengn, College Pk, MD 20742 USA. [Wu, Hsuan-Chen; Tsao, Chen-Yu; Quan, David N.; Carter, Karen K.; Terrell, Jessica L.; Zargar, Amin; Payne, Gregory F.; Bentley, William E.] Univ Maryland, Inst Biosci & Biotechnol Res, College Pk, MD 20742 USA. [Cheng, Yi; Rubloff, Gary W.] Univ Maryland, Dept Mat Sci & Engn, College Pk, MD 20742 USA. [Servinsky, Matthew D.] USA, Sensors & Elect Devices Directorate, Res Lab, Adelphi, MD USA. [Carter, Karen K.; Zargar, Amin; Bentley, William E.] Univ Maryland, Dept Chem & Biomol Engn, College Pk, MD 20742 USA. [Valdes, James J.] USA, Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD USA. RP Bentley, WE (reprint author), Univ Maryland, Inst Biosci & Biotechnol Res, 5115 Plant Sci Bldg, College Pk, MD 20742 USA. EM bentley@umd.edu RI Cheng, Yi/E-7670-2010; Rubloff, Gary/D-4142-2009; OI Cheng, Yi/0000-0001-9776-395X; Rubloff, Gary/0000-0002-1901-3982; WU, HSUAN-CHEN/0000-0002-7837-1333 FU Defense Threat Reduction Agency (DTRA) [BO085PO008]; Office of Naval Research [N000141010446]; National Science Foundation [EFRI-0735987]; R.W. Deutsch Foundation FX We would like to thank Dr Jennifer Grandis for generously providing the PCI-15B cell line, Dr George Georgiou for kindly providing the ompA surface display vector, and Dr Eiry Kobatake for providing the Streptococcal protein G vector. This research was funded by the Defense Threat Reduction Agency (DTRA, BO085PO008), the Office of Naval Research (N000141010446), the National Science Foundation (EFRI-0735987) and the R.W. Deutsch Foundation. NR 49 TC 23 Z9 23 U1 2 U2 42 PU NATURE PUBLISHING GROUP PI NEW YORK PA 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA SN 1744-4292 J9 MOL SYST BIOL JI Mol. Syst. Biol. PD JAN PY 2013 VL 9 AR 636 DI 10.1038/msb.2012.71 PG 8 WC Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA 082TS UT WOS:000314415800006 PM 23340842 ER PT J AU Rabaa, MA Klungthong, C Yoon, IK Holmes, EC Chinnawirotpisan, P Thaisomboonsuk, B Srikiatkhachorn, A Rothman, AL Tannitisupawong, D Aldstadt, J Nisalak, A Mammen, MP Gibbons, RV Endy, TP Fansiri, T Scott, TW Jarman, RG AF Rabaa, Maia A. Klungthong, Chonticha Yoon, In-Kyu Holmes, Edward C. Chinnawirotpisan, Piyawan Thaisomboonsuk, Butsaya Srikiatkhachorn, Anon Rothman, Alan L. Tannitisupawong, Darunee Aldstadt, Jared Nisalak, Ananda Mammen, Mammen P. Gibbons, Robert V. Endy, Timothy P. Fansiri, Thanyalak Scott, Thomas W. Jarman, Richard G. TI Frequent In-Migration and Highly Focal Transmission of Dengue Viruses among Children in Kamphaeng Phet, Thailand SO PLOS NEGLECTED TROPICAL DISEASES LA English DT Article ID PRIMARY-SCHOOL CHILDREN; POLYMERASE CHAIN-REACTION; HEMORRHAGIC-FEVER; INFECTIONS; EPIDEMIOLOGY; INAPPARENT; VILLAGES AB Revealing the patterns and determinants of the spread of dengue virus (DENV) at local scales is central to understanding the epidemiology and evolution of this major human pathogen. We performed a phylogenetic analysis of the envelope (E) genes of DENV-1, -2, -3, and -4 isolates (involving 97, 23, 5, and 74 newly collected sequences, respectively) sampled from school-based cohort and village-based cluster studies in Kamphaeng Phet, Thailand, between 2004 and 2007. With these data, we sought to describe the spatial and temporal patterns of DENV spread within a rural population where a future vaccine efficacy trial is planned. Our analysis revealed considerable genetic diversity within the study population, with multiple lineages within each serotype circulating for various lengths of time during the study period. These results suggest that DENV is frequently introduced into both semi-urban and rural areas in Kamphaeng Phet from other populations. In contrast, the persistence of viral lineages across sampling years was observed less frequently. Analysis of phylogenetic clustering indicated that DENV transmission was highly spatially and temporally focal, and that it occurred in homes rather than at school. Overall, the strength of temporal clustering suggests that seasonal bottlenecks in local DENV populations facilitate the invasion and establishment of viruses from outside of the study area, in turn reducing the extent of lineage persistence. C1 [Rabaa, Maia A.; Holmes, Edward C.] Penn State Univ, Dept Biol, Ctr Infect Dis Dynam, University Pk, PA 16802 USA. [Klungthong, Chonticha; Yoon, In-Kyu; Chinnawirotpisan, Piyawan; Thaisomboonsuk, Butsaya; Tannitisupawong, Darunee; Nisalak, Ananda; Mammen, Mammen P.; Gibbons, Robert V.; Jarman, Richard G.] Armed Forces Res Inst Med Sci, Dept Virol, Bangkok 10400, Thailand. [Holmes, Edward C.; Scott, Thomas W.] NIH, Fogarty Int Ctr, Bethesda, MD 20892 USA. [Srikiatkhachorn, Anon] Univ Massachusetts, Sch Med, Dept Med, Div Infect Dis & Immunol, Worcester, MA USA. [Rothman, Alan L.] Univ Rhode Isl, Inst Immunol & Informat, Providence, RI 02908 USA. [Aldstadt, Jared] SUNY Buffalo, Dept Geog, Buffalo, NY 14260 USA. [Endy, Timothy P.] SUNY Syracuse, Dept Infect Dis, Syracuse, NY USA. [Fansiri, Thanyalak] Armed Forces Res Inst Med Sci, Dept Entomol, Bangkok 10400, Thailand. [Scott, Thomas W.] Univ Calif Davis, Dept Entomol, Davis, CA 95616 USA. RP Rabaa, MA (reprint author), Penn State Univ, Dept Biol, Ctr Infect Dis Dynam, University Pk, PA 16802 USA. EM rick.jarman@us.army.mil RI Aldstadt, Jared/A-8508-2009; OI Aldstadt, Jared/0000-0001-9162-7439; Rabaa, Maia/0000-0003-0529-2228; Holmes, Edward/0000-0001-9596-3552 FU United States National Institutes of Health [P01 AI34533, R01 GM083224, R01 GM087405]; United States Military Infectious Diseases Research Program [S0016-04-AF]; Research and Policy for Infectious Disease Dynamics (RAPIDD) program of the Science and Technology Directorate, Department of Homeland Security; Fogarty International Center, National Institutes of Health; Bill & Melinda Gates Foundation [OPP52250]; National Science Foundation Graduate Research Fellowship FX This work was supported by the United States National Institutes of Health [grant numbers P01 AI34533, R01 GM083224 and R01 GM087405]; United States Military Infectious Diseases Research Program [grant number S0016-04-AF]; the Research and Policy for Infectious Disease Dynamics (RAPIDD) program of the Science and Technology Directorate, Department of Homeland Security, and the Fogarty International Center, National Institutes of Health; and the Bill & Melinda Gates Foundation (OPP52250). Funding to MAR was provided by a National Science Foundation Graduate Research Fellowship. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. NR 27 TC 13 Z9 13 U1 1 U2 14 PU PUBLIC LIBRARY SCIENCE PI SAN FRANCISCO PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA SN 1935-2735 J9 PLOS NEGLECT TROP D JI Plos Neglect. Trop. Dis. PD JAN PY 2013 VL 7 IS 1 AR e1990 DI 10.1371/journal.pntd.0001990 PG 14 WC Infectious Diseases; Parasitology; Tropical Medicine SC Infectious Diseases; Parasitology; Tropical Medicine GA 081ZB UT WOS:000314360200020 PM 23350000 ER PT J AU Mehta, VM Knutson, CL Rosenberg, NJ Olsen, JR Wall, NA Bernadt, TK Hayes, MJ AF Mehta, Vikram M. Knutson, Cody L. Rosenberg, Norman J. Olsen, J. Rolf Wall, Nicole A. Bernadt, Tonya K. Hayes, Michael J. TI Decadal Climate Information Needs of Stakeholders for Decision Support in Water and Agriculture Production Sectors: A Case Study in the Missouri River Basin SO WEATHER CLIMATE AND SOCIETY LA English DT Article ID CONTERMINOUS UNITED-STATES; VARIABILITY PHENOMENA; SURFACE-TEMPERATURE; SIMULATED IMPACTS; ATLANTIC-OCEAN; PACIFIC; PREDICTION; PRECIPITATION; YIELDS; MODEL AB Many decadal climate prediction efforts have been initiated under phase 5 of the World Climate Research Programme Coupled Model Intercomparison Project. There is considerable ongoing discussion about model deficiencies, initialization techniques, and data requirements, but not much attention is being given to decadal climate information (DCI) needs of stakeholders for decision support. Here, the authors report the results of exploratory activities undertaken to assess DCI needs in water resources and agriculture sectors, using the Missouri River basin as a case study. This assessment was achieved through discussions with 120 stakeholders. Stakeholders' awareness of decadal dry and wet spells and their societal impacts in the basin are described, and stakeholders' DCI needs and potential barriers to their use of DCI are enumerated. The authors find that impacts, including economic impacts, of decadal climate variability (DCV) on water and agricultural production in the basin are distinctly identifiable and characterizable. Stakeholders have clear notions about their needs for DCI and have offered specific suggestions as to how these might be met. However, while stakeholders are eager to have climate information, including decadal climate outlooks (DCOs), there are many barriers to the use of such information. The first and foremost barrier is that the credibility of DCOs is yet to be established. Second, the nature of institutional rules and regulations, laws, and legal precedents that pose obstacles to the use of DCOs must be better understood and means to modify these, where possible, must be sought. For the benefit of climate scientists, these and other stakeholder needs are also articulated in this paper. C1 [Mehta, Vikram M.; Rosenberg, Norman J.] Ctr Res Changing Earth Syst, Catonsville, MD 21228 USA. [Knutson, Cody L.; Wall, Nicole A.; Bernadt, Tonya K.; Hayes, Michael J.] Univ Nebraska, Natl Drought Mitigat Ctr, Lincoln, NE USA. [Olsen, J. Rolf] US Army Corps Engineers, Inst Water Resources, Alexandria, VA USA. RP Mehta, VM (reprint author), Ctr Res Changing Earth Syst, 5523 Res Pk Dr,Suite 315, Catonsville, MD 21228 USA. EM vikram@crces.org FU NOAA/Climate Program Office/Sectoral Applications Research Program [NA06OAR43100681, NA08OAR431067] FX This research was supported by NOAA/Climate Program Office/Sectoral Applications Research Program Grants NA06OAR43100681 and NA08OAR431067. We are grateful to Doug Kluck (NOAA) and Jesse Aber (State of Montana) for facilitating workshops and other interactions with stakeholders. We are grateful to the editor and three anonymous reviewers for their insightful and constructive comments and suggestions that have improved this manuscript substantially. NR 28 TC 7 Z9 7 U1 2 U2 20 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 USA SN 1948-8327 J9 WEATHER CLIM SOC JI Weather Clim. Soc. PD JAN PY 2013 VL 5 IS 1 BP 27 EP 42 DI 10.1175/WCAS-D-11-00063.1 PG 16 WC Environmental Studies; Meteorology & Atmospheric Sciences SC Environmental Sciences & Ecology; Meteorology & Atmospheric Sciences GA 082JJ UT WOS:000314387800004 ER PT J AU Sabatini, JJ Raab, JM Hann, RK Freeman, CT AF Sabatini, Jesse J. Raab, James M. Hann, Ronald K., Jr. Freeman, Cathleen T. TI Brighter- and Longer-Burning Barium-Free Illuminants for Military and Civilian Pyrotechnics SO ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE LA English DT Article DE Energetic materials; Pyrotechnics; Illuminants; Green chemistry; High-temperature chemistry ID LIGHT ILLUMINANTS; PERCHLORATE-FREE; BORON AB The development of barium-free pyrotechnic illuminants is described. Heavy metal barium nitrate oxidizer and strontium nitrate oxidizer were replaced with sodium nitrate to adequately address environmental concerns while providing the brightest possible illuminant. The new formulations further address environmental concerns and mitigate single-point-of-failure through the replacement of polyester-based Laminac 4116/Lupersol binder system with the epoxy-based Epon 813/Versamid 140 binder system. The new formulations were found to burn longer and brighter than the control with a low sensitivity to various ignition stimuli. C1 [Sabatini, Jesse J.; Freeman, Cathleen T.] USA, RDECOM ARDEC, Pyrotech Technol & Prototyping Div, Picatinny Arsenal, NJ 07806 USA. [Raab, James M.; Hann, Ronald K., Jr.] US Mil Acad, Dept Chem & Life Sci, West Point, NY 10996 USA. RP Sabatini, JJ (reprint author), USA, RDECOM ARDEC, Pyrotech Technol & Prototyping Div, Bldg 3124, Picatinny Arsenal, NJ 07806 USA. EM jesse.j.sabatini.civ@mail.mil FU US Army (Picatinny Arsenal, NJ) FX The authors are indebted to the US Army (Picatinny Arsenal, NJ) for funding of this work, and to Mr. Henry Grau for providing thermal onset values. Dr. Karl D. Oyler is gratefully acknowledged for providing particle size data of the ingredients used. The authors thank The Department of Chemistry & Life Sciences at West Point Military Academy for their collaborations as part of the Academic Individual Advanced Development (AIAD) program. The authors wish to acknowledge Fort Benning Infantry School for providing a written endorsement letter in pursuit of the disclosed Mg/NaNO3-based M159 cluster illuminants. NR 26 TC 7 Z9 7 U1 0 U2 6 PU WILEY-V C H VERLAG GMBH PI WEINHEIM PA BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY SN 0044-2313 J9 Z ANORG ALLG CHEM JI Z. Anorg. Allg. Chem. PD JAN PY 2013 VL 639 IS 1 BP 25 EP 30 DI 10.1002/zaac.201200460 PG 6 WC Chemistry, Inorganic & Nuclear SC Chemistry GA 075HF UT WOS:000313874700005 ER PT J AU Walker, JJ Cleveland, LM Davis, JL Seales, JS AF Walker, Jennifer Junnila Cleveland, Leanne M. Davis, Jenny L. Seales, Jennifer S. TI Audiometry Screening and Interpretation SO AMERICAN FAMILY PHYSICIAN LA English DT Article ID INDUCED HEARING-LOSS; HEALTH; CARE; RECOMMENDATIONS; CONSERVATION; ADOLESCENTS; PREVALENCE; INJURY; ADULTS AB The prevalence of hearing loss varies with age, affecting at least 25 percent of patients older than 50 years and more than 50 percent of those older than 80 years. Adolescents and young adults represent groups in which the prevalence of hearing loss is increasing and may therefore benefit from screening. If offered, screening can be performed periodically by asking the patient or family if there are perceived hearing problems, or by using clinical office tests such as whispered voice, finger rub, or audiometry. Audiometry in the family medicine clinic setting is a relatively simple procedure that can be interpreted by a trained health care professional. Pure-tone testing presents tones across the speech spectrum (500 to 4,000 Hz) to determine if the patient's hearing levels fall within normal limits. A quiet testing environment, calibrated audiometric equipment, and appropriately trained personnel are required for in-office testing. Pure-tone audiometry may help physicians appropriately refer patients to an audiologist or otolaryngologist. Unilateral or asymmetrical hearing loss can be symptomatic of a central nervous system lesion and requires additional evaluation. (Am Fam Physician. 2013;87(1) :41-47. Copyright (C) 2013 American Academy of Family Physicians.) C1 [Walker, Jennifer Junnila] USA, Hlth Clin, Schofield Barracks, HI 96857 USA. [Cleveland, Leanne M.] Ft Richardson Troop Hlth Clin, Joint Base Elmendorf Ric, AK USA. [Davis, Jenny L.] Landstuhl Reg Med Ctr, Landstuhl, Germany. [Seales, Jennifer S.] Gen Leonard Wood Army Community Hosp, Ft Leonard Wood, MO USA. RP Walker, JJ (reprint author), USA, Hlth Clin, Bldg 683, Schofield Barracks, HI 96857 USA. NR 40 TC 8 Z9 8 U1 2 U2 8 PU AMER ACAD FAMILY PHYSICIANS PI KANSAS CITY PA 8880 WARD PARKWAY, KANSAS CITY, MO 64114-2797 USA SN 0002-838X J9 AM FAM PHYSICIAN JI Am. Fam. Physician PD JAN 1 PY 2013 VL 87 IS 1 BP 41 EP 47 PG 7 WC Primary Health Care; Medicine, General & Internal SC General & Internal Medicine GA 068QN UT WOS:000313381400007 PM 23317024 ER PT J AU Tagawa, C Speakman, M AF Tagawa, Chelsea Speakman, Mori TI Papular Rash in a Child After a Fever SO AMERICAN FAMILY PHYSICIAN LA English DT Editorial Material C1 [Tagawa, Chelsea; Speakman, Mori] Tripler Army Med Ctr, Honolulu, HI 96859 USA. RP Tagawa, C (reprint author), Tripler Army Med Ctr, Honolulu, HI 96859 USA. EM chelsea.w.tagawa@us.army.mil NR 5 TC 0 Z9 0 U1 0 U2 1 PU AMER ACAD FAMILY PHYSICIANS PI KANSAS CITY PA 8880 WARD PARKWAY, KANSAS CITY, MO 64114-2797 USA SN 0002-838X J9 AM FAM PHYSICIAN JI Am. Fam. Physician PD JAN 1 PY 2013 VL 87 IS 1 BP 59 EP 60 PG 2 WC Primary Health Care; Medicine, General & Internal SC General & Internal Medicine GA 068QN UT WOS:000313381400009 PM 23317026 ER PT J AU Thomas, SJ Eckels, KH Carletti, I De La Barrera, R Dessy, F Fernandez, S Putnak, R Toussaint, JF Sun, W Bauer, K Gibbons, RV Innis, BL AF Thomas, Stephen J. Eckels, Kenneth H. Carletti, Isabelle De La Barrera, Rafael Dessy, Francis Fernandez, Stefan Putnak, Robert Toussaint, Jean-Francois Sun, Wellington Bauer, Kristen Gibbons, Robert V. Innis, Bruce L. TI A Phase II, Randomized, Safety and Immunogenicity Study of a Re-Derived, Live-Attenuated Dengue Virus Vaccine in Healthy Adults SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID FLAVIVIRUS-NAIVE ADULTS; HEMORRHAGIC-FEVER; CANDIDATE; FORMULATIONS; SEROTYPES; SEVERITY; CELLS; TRIAL AB Two formulations of a new live tetravalent dengue virus (DENV) vaccine produced using re-derived master seeds from a precursor vaccine and that same precursor vaccine as a control were compared in a placebo-controlled, randomized, observer-blind, phase II trial of 86 healthy adults. Two vaccine doses were administered 6 months apart; a third dose was offered to a subset. Symptoms and signs of dengue-like illness reported after vaccination were mild to moderate, transient, and occurred with similar frequency among recipients of the new DENV vaccine and placebo, except for rash. Neither dengue nor vaccine-related serious adverse events were reported. The first DENV vaccine dose was moderately immunogenic; the second dose increased the potency and breadth of the neutralizing antibody response. Tetravalent response rates to the new formulations were 60% and 66.7% in unprimed subjects. A third dose did not increase tetravalent antibody rates. The new DENV vaccine candidates merit additional evaluation. C1 [Thomas, Stephen J.; Putnak, Robert] Walter Reed Army Inst Res, Viral Dis Branch, Silver Spring, MD 20910 USA. [Eckels, Kenneth H.; De La Barrera, Rafael] Walter Reed Army Inst Res, Div Regulated Activ, Pilot Bioprod Facil, Silver Spring, MD 20910 USA. [Dessy, Francis] GlaxoSmithKline Vaccines, Vaccine Discovery & Dev, Viral Funct Immunol, Wavre, Belgium. [Gibbons, Robert V.] US Army Med Component Armed Forces Res Inst Med S, Dept Virol, Bangkok, Thailand. [Innis, Bruce L.] GlaxoSmithKline Vaccines, King Of Prussia, PA USA. RP Thomas, SJ (reprint author), Walter Reed Army Inst Res, Viral Dis Branch, 503 Robert Grant Ave, Silver Spring, MD 20910 USA. EM stephen.thomas@amedd.army.mil; kenneth.eckels@amedd.army.mil; isabelle.x.carletti@gsk.com; rafael.delabarrera@amedd.army.mil; francis.dessy@gsk.com; Stefan.Fernandez@afrims.org; robert.putnak@amedd.army.mil; jean-francois.x.toussaint@gsk.com; Wellington.Sun@fda.hhs.gov; Kristen.Bauer@afrims.org; Robert.gibbons@afrims.org; bruce.2.innis@gsk.com FU US Army Medical Research and Materiel Command (Fort Detrick, MD); GlaxoSmithKline Biologicals S.A. (Rixensart, Belgium); US Department of Defense FX This work was funded by US Army Medical Research and Materiel Command (Fort Detrick, MD) and GlaxoSmithKline Biologicals S.A. (Rixensart, Belgium).; S.J.T. received travel grants from the US Department of Defense. K.H.E., R.P., W.S., and B.L.I. are named inventors on several patents or patent applications related to the field of vaccine development. I.C., F.D., J.-F.T. and B.L.I. are employees of the GSK group of companies. R.P. received royalties from GSK. J.-F.T. and B.L.I. own shares and options to shares in GSK. All other authors import no potential conflicts. The opinions or assertions contained herein are the private views of the authors and are not to be construed as reflecting the official views of the US Army or the US Department of Defense. NR 23 TC 38 Z9 40 U1 0 U2 12 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD JAN PY 2013 VL 88 IS 1 BP 73 EP 88 DI 10.4269/ajtmh.2012.12-0361 PG 16 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA 073QL UT WOS:000313757500013 PM 23208878 ER PT J AU Mait, JN Mendez, E Peyghambarian, N Poon, TC AF Mait, Joseph N. Mendez, Eugenio Peyghambarian, Nasser Poon, T. -C. TI Applied Optics Golden Anniversary Commemorative Reviews: introduction SO APPLIED OPTICS LA English DT Review AB Applied Optics presents three special issues to end its retrospective of Applied Optics' 50 years. The special issues are interference, interferometry, and phase; imaging, optical processing, and telecommunications; and polarization and scattering. The issues, which contain 19 commemorative reviews from some of the journal's luminaries, are summarized. (c) 2012 Optical Society of America C1 [Mait, Joseph N.] USA, Res Lab, RDRL SER, Adelphi, MD 20783 USA. RP Mait, JN (reprint author), USA, Res Lab, RDRL SER, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM joseph.n.mait2.civ@mail.mil NR 0 TC 0 Z9 0 U1 1 U2 8 PU OPTICAL SOC AMER PI WASHINGTON PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA SN 1559-128X EI 2155-3165 J9 APPL OPTICS JI Appl. Optics PD JAN 1 PY 2013 VL 52 IS 1 BP CR1 EP CR3 DI 10.1364/AO.52.000CR1 PG 3 WC Optics SC Optics GA 073LZ UT WOS:000313745800048 PM 23292429 ER PT J AU Bair, EH AF Bair, Edward H. TI Forecasting artificially-triggered avalanches in storm snow at a large ski area SO COLD REGIONS SCIENCE AND TECHNOLOGY LA English DT Article DE Snow; Avalanche; Ski area ID NEAREST-NEIGHBORS; MAMMOTH MOUNTAIN; SLAB AVALANCHES; STABILITY; VERIFICATION; DANGER; MODEL AB At ski areas, a majority of avalanches fail in storm snow. Using thousands of observations from avalanche control work at Mammoth Mountain, CA, USA, a large coastal ski area, I analyzed important predictors of avalanche activity. New (24 h) precipitation increased avalanche activity, while changing temperatures and different wind patterns had no effect. If slopes remained undisturbed for one day after snowfall, the number and size of avalanches as well as the explosive yield (avalanches per shot) were all significantly reduced. I also examined a smaller dataset of Extended Column Test (ECT) results and their relation to avalanche activity. ECT propagation was a powerful predictor; days with ECTs that propagated had significantly more avalanches and larger sizes. Days with propagating ECTs also had significantly greater new snow amounts, with a threshold value of 0.29 m of new snow, very close to the 031 m threshold from Atwater's 10 factors. That new precipitation above a threshold causes greater avalanche activity is not a new finding; the new finding is that ECT propagation (versus non-propagation) also has a similar new snow threshold. Thus, I suggest that ECT propagation is an important tool to predict explosively-triggered avalanches in storm snow. (C) 2012 Elsevier B.V. All rights reserved. C1 [Bair, Edward H.] USA, Corps Engineers Cold Reg Res & Engn Lab, Hanover, NH USA. RP Bair, EH (reprint author), Univ Calif Santa Barbara, Earth Res Inst, Santa Barbara, CA 93106 USA. EM nbair@eri.ucsb.edu NR 62 TC 0 Z9 0 U1 1 U2 8 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0165-232X EI 1872-7441 J9 COLD REG SCI TECHNOL JI Cold Reg. Sci. Tech. PD JAN PY 2013 VL 85 BP 261 EP 269 DI 10.1016/j.coldregions.2012.10.003 PG 9 WC Engineering, Environmental; Engineering, Civil; Geosciences, Multidisciplinary SC Engineering; Geology GA 073WP UT WOS:000313774100027 ER PT J AU Werner, K St-Surin-Lord, S Sperling, LC AF Werner, Kimberly St-Surin-Lord, Sharleen Sperling, Leonard C. TI Pili Annulati Associated With Hair Fragility: Cause or Coincidence? SO CUTIS LA English DT Article ID MICROSCOPY; FOLLICLES AB Pili annulati is a disorder that produces a spangled appearance to the hair, caused by alternating light and dark banding of hair shafts. This phenomenon is created by abnormal cavities in the cortex of the hair shaft, which produces lighter bands seen on clinical examination. Complications of pili annulati are limited; the most noicoworthy complication is increased breakage secondary to weathering of the abnormal hair shafts. We report a case of a 14-year-old adolescent girl with pili annulati and progressive hair loss of 2 months' duration. Most of her hairs were notably short, spangled, and lusterless with light and dark banding observed with handheld magnification. light microscopy demonstrated alternating light and dark bands, and the dark bands had the typical appearance of air-filled spaces. Gentler hair grooming practices were recommended, and at a follow-up visit, the appearance of the hair had improved with darker and longer shafts. This case should alert clinicians to look for,pili annulati when hair fragility is present. Cutis. 2013;91:36-38. C1 [Werner, Kimberly] Walter Reed Army Med Ctr, Washington, DC 20307 USA. [St-Surin-Lord, Sharleen] Howard Univ, Coll Med, Washington, DC USA. [Sperling, Leonard C.] Uniformed Serv Univ Hlth Sci, Dept Dermatol, Bethesda, MD 20814 USA. RP Werner, K (reprint author), Walter Reed Army Med Ctr, 6900 Georgia Ave NW, Washington, DC 20307 USA. EM kimberlyawerner@gmail.com NR 5 TC 2 Z9 2 U1 2 U2 2 PU QUADRANT HEALTHCOM INC PI PARSIPPANY PA 7 CENTURY DRIVE, STE 302, PARSIPPANY, NJ 07054-4603 USA SN 0011-4162 J9 CUTIS JI Cutis PD JAN PY 2013 VL 91 IS 1 BP 36 EP 38 PG 3 WC Dermatology SC Dermatology GA 076AV UT WOS:000313929800008 PM 23461057 ER PT J AU Muhie, S Hammamieh, R Cummings, C Yang, D Jett, M AF Muhie, S. Hammamieh, R. Cummings, C. Yang, D. Jett, M. TI Transcriptome characterization of immune suppression from battlefield-like stress SO GENES AND IMMUNITY LA English DT Article DE microarray; immune response; battlefield-like stress; Army Rangers; RASP ID FACTOR-BINDING SITES; PSYCHOLOGICAL STRESS; MICRORNA-155; VACCINE; CELLS; DEPRESSION; PROFILES; DISEASE; ALTERS; MICE AB Transcriptome alterations of leukocytes from soldiers who underwent 8 weeks of Army Ranger training (RASP, Ranger Assessment and Selection Program) were analyzed to evaluate impacts of battlefield-like stress on the immune response. About 1400 transcripts were differentially expressed between pre- and post-RASP leukocytes. Upon functional analysis, immune response was the most enriched biological process, and most of the transcripts associated with the immune response were downregulated. Microbial pattern recognition, chemotaxis, antigen presentation and T-cell activation were among the most downregulated immune processes. Transcription factors predicted to be stress-inhibited (IRF7, RELA, NF kappa B1, CREB1, IRF1 and HMGB) regulated genes involved in inflammation, maturation of dendritic cells and glucocorticoid receptor signaling. Many altered transcripts were predicted to be targets of stress-regulated microRNAs. Post-RASP leukocytes exposed ex vivo to Staphylococcal enterotoxin B showed a markedly impaired immune response to this superantigen compared with pre-RASP leukocytes, consistent with the suppression of the immune response revealed by transcriptome analyses. Our results suggest that suppression of antigen presentation and lymphocyte activation pathways, in the setting of normal blood cell counts, most likely contribute to the poor vaccine response, impaired wound healing and infection susceptibility associated with chronic intense stress. Genes and Immunity (2013) 14, 19-34; doi: 10.1038/gene.2012.49; published online 25 October 2012 C1 [Muhie, S.; Hammamieh, R.; Jett, M.] USA, Integrat Syst Biol Program, Ctr Environm Hlth Res, Ft Detrick, MD 21702 USA. [Yang, D.] Georgetown Univ, Dept Chem, Washington, DC 20057 USA. RP Jett, M (reprint author), USA, Integrat Syst Biol Program, Ctr Environm Hlth Res, Ft Detrick, MD 21702 USA. EM marti.jett@us.army.mil RI Yang, David/A-7294-2009 FU Defense Threat Reduction Agency FX We are grateful to the Defense Threat Reduction Agency for funding. NR 29 TC 4 Z9 5 U1 0 U2 13 PU NATURE PUBLISHING GROUP PI LONDON PA MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND SN 1466-4879 J9 GENES IMMUN JI Genes Immun. PD JAN PY 2013 VL 14 IS 1 BP 19 EP 34 DI 10.1038/gene.2012.49 PG 16 WC Genetics & Heredity; Immunology SC Genetics & Heredity; Immunology GA 078JW UT WOS:000314095700004 PM 23096155 ER PT J AU Govoni, MA AF Govoni, Mark A. TI Range-Doppler Resolution of the Linear-FM Noise Radar Waveform SO IEEE TRANSACTIONS ON AEROSPACE AND ELECTRONIC SYSTEMS LA English DT Article ID PHASE AB This research considers the linear-FM (LFM) of a noise radar waveform for resolving targets when channel noise and four popular radar sidelobe weighting functions are considered. By using large time-bandwidth products and systematically varying the phase scaling factor kappa, results from the digital matched filter output provide evidence that the LFM noise waveform 1) has range-Doppler resolution similar to conventional chirp waveforms and 2) has a low probability of intercept (LPI) similar to random noise waveforms. We acquire the results using a computer-based simulation and verify the location of target peaks using the chirp waveform output for both stationary and moving target cases. C1 USA, RDECOM CERDEC 12WD, Radar Applicat Branch, RDER IWR RA, Aberdeen Proving Ground, MD 21005 USA. RP Govoni, MA (reprint author), USA, RDECOM CERDEC 12WD, Radar Applicat Branch, RDER IWR RA, Bldg 6003, Aberdeen Proving Ground, MD 21005 USA. EM mark.anthony.govoni@us.army.mil NR 14 TC 8 Z9 12 U1 1 U2 16 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0018-9251 EI 1557-9603 J9 IEEE T AERO ELEC SYS JI IEEE Trans. Aerosp. Electron. Syst. PD JAN PY 2013 VL 49 IS 1 BP 658 EP 664 PG 8 WC Engineering, Aerospace; Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA 072QJ UT WOS:000313687000044 ER PT J AU Panchal, RG Lane, D Boshoff, HI Butler, MM Moir, DT Bowlin, TL Bavari, S AF Panchal, Rekha G. Lane, Douglas Boshoff, Helena I. Butler, Michelle M. Moir, Donald T. Bowlin, Terry L. Bavari, Sina TI Bis-imidazolinylindoles are active against methicillin-resistant Staphylococcus aureus and multidrug-resistant Mycobacterium tuberculosis SO JOURNAL OF ANTIBIOTICS LA English DT Article DE antibacterials; antibiotic resistance; bis-imidazolinylindoles; broad-spectrum ID PUBLIC-HEALTH THREAT; EMERGENCE C1 [Panchal, Rekha G.; Bavari, Sina] USA, Target Discovery & Expt Microbiol Dept, Med Res Inst Infect Dis, Frederick, MD 21702 USA. [Lane, Douglas] NCI, Target Struct Based Drug Discovery Grp, SAIC Frederick Inc, Frederick, MD 21701 USA. [Boshoff, Helena I.] NIAID, TB Res Sect, LCID, NIH, Bethesda, MD 20892 USA. [Butler, Michelle M.; Moir, Donald T.; Bowlin, Terry L.] Microbiotix Inc, Worcester, MA USA. RP Panchal, RG (reprint author), USA, Target Discovery & Expt Microbiol Dept, Med Res Inst Infect Dis, 1425 Porter St, Frederick, MD 21702 USA. EM rekha.panchal@amedd.army.mil FU Defense Threat Reduction Agency (DTRA); National Cancer Institute, National Institutes of Health [N01-CO-12400]; NIH, NIAID; Developmental Therapeutics Program in the Division of Cancer Treatment and Diagnosis of the National Cancer Institute; [HDTRA1-06-C-0042] FX This project has been funded in part by HDTRA1-06-C-0042 to Microbiotix Inc. and by Defense Threat Reduction Agency (DTRA) to RGP and SB, and with federal funds from the National Cancer Institute, National Institutes of Health (under contract N01-CO-12400) and in part by the Intramural Research Program of the NIH, NIAID. The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products or organizations imply endorsement by the US Government. This research was supported in part by the Developmental Therapeutics Program in the Division of Cancer Treatment and Diagnosis of the National Cancer Institute. Opinions, interpretations, conclusions and recommendations are those of the authors and are not necessarily endorsed by the US Army. NR 8 TC 4 Z9 4 U1 1 U2 4 PU JAPAN ANTIBIOTICS RESEARCH ASSOC PI TOKYO PA 2 20 8 KAMIOSAKI SHINAGAWA KU, TOKYO, 141, JAPAN SN 0021-8820 J9 J ANTIBIOT JI J. Antibiot. PD JAN PY 2013 VL 66 IS 1 BP 47 EP 49 DI 10.1038/ja.2012.93 PG 3 WC Biotechnology & Applied Microbiology; Immunology; Microbiology; Pharmacology & Pharmacy SC Biotechnology & Applied Microbiology; Immunology; Microbiology; Pharmacology & Pharmacy GA 079JB UT WOS:000314165300008 PM 23149517 ER PT J AU Solyman, SM Black, CC Duim, B Perreten, V van Duijkeren, E Wagenaar, JA Eberlein, LC Sadeghi, LN Videla, R Bemis, DA Kania, SA AF Solyman, S. M. Black, C. C. Duim, B. Perreten, V. van Duijkeren, E. Wagenaar, J. A. Eberlein, L. C. Sadeghi, L. N. Videla, R. Bemis, D. A. Kania, S. A. TI Multilocus Sequence Typing for Characterization of Staphylococcus pseudintermedius SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article ID METHICILLIN-RESISTANT; ANTIBIOTIC-RESISTANCE; NORTH-AMERICA; DOGS; INTERMEDIUS; MECA; CLONES; AUREUS; SUSCEPTIBILITY; EMERGENCE AB Staphylococcus pseudintermedius is an opportunistic pathogen in dogs. Four housekeeping genes with allelic polymorphisms were identified and used to develop an expanded multilocus sequence typing (MLST) scheme. The new seven-locus technique shows S. pseudintermedius to have greater genetic diversity than previous methods and discriminates more isolates based upon host origin. C1 [Solyman, S. M.; Black, C. C.; Eberlein, L. C.; Sadeghi, L. N.; Videla, R.; Bemis, D. A.; Kania, S. A.] Univ Tennessee, Coll Vet Med, Dept Biomed & Diagnost Sci, Knoxville, TN 37996 USA. [Black, C. C.] USA, Vet Corps, Silver Spring, MD USA. [Duim, B.; Wagenaar, J. A.] Univ Utrecht, Fac Vet Med, Dept Infect Dis & Immunol, Utrecht, Netherlands. [Perreten, V.] Univ Bern, Inst Vet Bacteriol, Bern, Switzerland. [van Duijkeren, E.] Natl Inst Publ Hlth & Environm, Lab Zoonoses & Environm Microbiol, NL-3720 BA Bilthoven, Netherlands. [Wagenaar, J. A.] Cent Vet Inst Wageningen, Lelystad, Netherlands. RP Kania, SA (reprint author), Univ Tennessee, Coll Vet Med, Dept Biomed & Diagnost Sci, Knoxville, TN 37996 USA. EM skania@utk.edu RI Black, Chad/B-2848-2011; OI Kania, Stephen/0000-0002-4490-7347 FU Center of Excellence in Livestock Diseases and Animal Health, University of Tennessee; American Kennel Club Canine Health Foundation; Culture and Education Bureau of the Arab Republic of Egypt FX This work was supported in part by grants from the Center of Excellence in Livestock Diseases and Animal Health, University of Tennessee and the American Kennel Club Canine Health Foundation. Samar Solyman is supported by a Ph.D. scholarship from the Culture and Education Bureau of the Arab Republic of Egypt. Study sponsors did not play any role in the study design, in the collection, analysis, and interpretation of data, in the writing of the manuscript, and in the decision to submit the manuscript for publication. NR 33 TC 30 Z9 30 U1 0 U2 6 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD JAN PY 2013 VL 51 IS 1 BP 306 EP 310 DI 10.1128/JCM.02421-12 PG 5 WC Microbiology SC Microbiology GA 078NF UT WOS:000314105100053 PM 23115265 ER PT J AU Li, HH Lin, LW Burks-Copes, KA AF Li, Honghai Lin, Lihwa Burks-Copes, Kelly A. TI Modeling of Coastal Inundation, Storm Surge, and Relative Sea-Level Rise at Naval Station Norfolk, Norfolk, Virginia, USA SO JOURNAL OF COASTAL RESEARCH LA English DT Article DE Nearshore hydrodynamic modeling; waves; synthetic tropical storms; extratropical storms; Hurricane Isabel; land flooding ID HURRICANES AB Li, H.; Lin, L., and Burks-Copes, K.A., 2013. Modeling of coastal inundation, storm surge, and relative sea-level rise at Naval Station Norfolk, Norfolk, Virginia, U.S.A. Journal of Coastal Research, 29(1), 18-30. Coconut Creek (Florida), ISSN 0749-0208. The potential risk and effects of storm-surge damage caused by the combination of hurricane-force waves, tides, and relative sea-level-rise (RSLR) scenarios were examined at the U.S. Naval Station, Norfolk, Virginia. A hydrodynamic and sediment transport modeling system validated with measured water levels from Hurricane Isabel was used to simulate two synthesized storms representing 50-year and 100-year return-period hurricanes, a northeaster, and five future RSLR scenarios to evaluate the combined impacts of inundation on this military installation in the lower Chesapeake Bay. The naval base topography and nearshore water body of Hampton Roads were included in the coastal modeling system (CMS), a suite of surge, circulation, wave, sediment transport, and morphology evolution models. The modeling domain was a rectangular area covering the entire Naval Station Norfolk in the Hampton Roads and the mouths of the James and Elizabeth rivers. A variable-resolution grid system was created with a finer resolution of 10 m in the naval base and a coarser resolution of 300 m in the regions away from the base. The boundary-forcing conditions to the CMS were regional storm surge produced by the ADvanced CIRCulation (ADCIRC),and wave conditions by the Simulating WAve Nearshore (SWAN) model. The CMS calculated the local water-surface elevation and storm-surge inundation for combined RSLR, surge, waves, and wind. Results indicate that synthetic storms would cause extensive inundation of coastal land around the naval base. Approximately 60% of the land would be under water with the 100-year storm for the present sea level, and 80% for estimated RSLR of 2 m. C1 [Li, Honghai; Lin, Lihwa] USA, Engineer Res & Dev Ctr, Coastal & Hydraul Lab, Vicksburg, MS 39180 USA. [Burks-Copes, Kelly A.] USA, Engineer Res & Dev Ctr, Environm Lab, Vicksburg, MS 39180 USA. RP Li, HH (reprint author), USA, Engineer Res & Dev Ctr, Coastal & Hydraul Lab, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM Honghai.Li@usace.army.mil FU Resource Conservation and Climate Change Program Area of the Strategic Environmental Research and Development Program; Coastal Inlets Research Program FX We thank the funding support by the Resource Conservation and Climate Change Program Area of the Strategic Environmental Research and Development Program and by the Coastal Inlets Research Program administered at Coastal and Hydraulics Laboratory under the Navigation Program for Headquarters, U.S. Army Corps of Engineers (USACE). We are grateful for the late Dr. Nicholas C. Kraus for his inspiration and encouragement toward the CMS application to this study. We also thank Dr. Julie D. Rosati, Dr. Zeki Demirbilek, and Ms. Mary A. Cialone of USACE, and two anonymous reviewers for reviewing and providing constructive comments on the manuscript. Permission was granted by the Chief, USACE, to publish this information. NR 25 TC 1 Z9 1 U1 10 U2 59 PU COASTAL EDUCATION & RESEARCH FOUNDATION PI LAWRENCE PA 810 EAST 10TH STREET, LAWRENCE, KS 66044 USA SN 0749-0208 J9 J COASTAL RES JI J. Coast. Res. PD JAN PY 2013 VL 29 IS 1 BP 18 EP 30 DI 10.2112/JCOASTRES-D-12-00056.1 PG 13 WC Environmental Sciences; Geography, Physical; Geosciences, Multidisciplinary SC Environmental Sciences & Ecology; Physical Geography; Geology GA 076AZ UT WOS:000313930200003 ER PT J AU Trahan, MJ Mukerjee, S Plichta, EJ Hendrickson, MA Abraham, KM AF Trahan, Matthew J. Mukerjee, Sanjeev Plichta, Edward J. Hendrickson, Mary A. Abraham, K. M. TI Studies of Li-Air Cells Utilizing Dimethyl Sulfoxide-Based Electrolyte SO JOURNAL OF THE ELECTROCHEMICAL SOCIETY LA English DT Article ID LITHIUM-OXYGEN BATTERY; IONIC LIQUID; CARBONATE ELECTROLYTES; POLYMER ELECTROLYTE; LI-O-2 BATTERIES; REDUCTION; STABILITY; PRODUCTS; ETHER AB Dimethyl Sulfoxide (DMSO) was evaluated as a practical solvent for the rechargeable lithium air battery. Redox characteristics of the dissolved oxygen and its reduction products in the presence of lithium hexafluorophosphate (LiPF6) supporting electrolyte were studied via cyclic, rotating disk (RDE) and ring-disk (RRDE) electrode voltammetry. The DMSO medium facilitates reversible reduction and oxidation processes in contrast to other solvent-based electrolytes studied. Galvanostatic discharge-charge cycling of the Li-O-2 cells has shown characteristics of rechargeability expected from voltammetric studies. Multiple high-efficiency discharge-charge cycles are possible if the depth of discharge of the carbon cathode is limited to avoid excessive passivation by the discharge products. The discharge voltage of this Li-O-2 cell is higher than cells assembled with other non-aqueous organic electrolytes, an attribute ascribed to the stability of superoxide (O-2(-)), the one-electron reduction product of oxygen. (C) 2012 The Electrochemical Society. [DOI: 10.1149/2.048302jes] All rights reserved. C1 [Trahan, Matthew J.; Mukerjee, Sanjeev; Abraham, K. M.] Northeastern Univ, Dept Chem & Chem Biol, Boston, MA 02115 USA. [Plichta, Edward J.; Hendrickson, Mary A.] USA, RDECOM CERDEC CP&I, Army Power Div, Aberdeen Proving Ground, MD 21005 USA. RP Trahan, MJ (reprint author), Northeastern Univ, Dept Chem & Chem Biol, Boston, MA 02115 USA. EM kmabraham@comcast.net FU US Army CERDEC [GTS-S-10-392] FX US Army CERDEC through Subcontract No GTS-S-10-392 supported this work. NR 34 TC 130 Z9 132 U1 11 U2 243 PU ELECTROCHEMICAL SOC INC PI PENNINGTON PA 65 SOUTH MAIN STREET, PENNINGTON, NJ 08534 USA SN 0013-4651 J9 J ELECTROCHEM SOC JI J. Electrochem. Soc. PY 2013 VL 160 IS 2 BP A259 EP A267 DI 10.1149/2.048302jes PG 9 WC Electrochemistry; Materials Science, Coatings & Films SC Electrochemistry; Materials Science GA 071HJ UT WOS:000313581600009 ER PT J AU Newman, S Gallinat, C Wright, J Enck, R Sampath, A Shen, HG Reed, M Wraback, M AF Newman, Scott Gallinat, Chad Wright, Jonathan Enck, Ryan Sampath, Anand Shen, Hongen Reed, Meredith Wraback, Michael TI Wavelength stable, p-side-down green light emitting diodes grown by molecular beam epitaxy SO JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B LA English DT Article ID MG; LAYERS AB p-side-down, single heterostructure n-InGaN/p-GaN light emitting diodes grown by molecular beam epitaxy exhibited stable peak emission wavelengths as long as 550nm for current densities in excess of 100 A/cm(2), and minimal efficiency droop up to 150 A/cm(2) without the use of an electron blocking layer. This behavior is consistent with the formation of a two-dimensional hole gas in the n-InGaN layer and a higher barrier to electron overflow in the conduction band due to the negative polarization charge at the n-InGaN/p-GaN interface. (C) 2013 American Vacuum Society. [http://dx.doi.org/10.1116/1.4769732] C1 [Newman, Scott; Gallinat, Chad; Wright, Jonathan; Enck, Ryan; Sampath, Anand; Shen, Hongen; Reed, Meredith; Wraback, Michael] USA, Sensors & Electron Device Directorate, Res Lab, RDRL SEE M, Adelphi, MD 20783 USA. RP Newman, S (reprint author), USA, Sensors & Electron Device Directorate, Res Lab, RDRL SEE M, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM meredith.l.reeed@us.army.mil FU Department of Energy [DE-PS26-09NT013775] FX The authors gratefully acknowledge support from the Department of Energy Grant No. DE-PS26-09NT013775. NR 16 TC 0 Z9 0 U1 1 U2 19 PU A V S AMER INST PHYSICS PI MELVILLE PA STE 1 NO 1, 2 HUNTINGTON QUADRANGLE, MELVILLE, NY 11747-4502 USA SN 1071-1023 J9 J VAC SCI TECHNOL B JI J. Vac. Sci. Technol. B PD JAN PY 2013 VL 31 IS 1 AR 010601 DI 10.1116/1.4769732 PG 3 WC Engineering, Electrical & Electronic; Nanoscience & Nanotechnology; Physics, Applied SC Engineering; Science & Technology - Other Topics; Physics GA 072LN UT WOS:000313672600022 ER PT J AU Endale, M Ekberg, A Alao, JP Akala, HM Ndakala, A Sunnerhagen, P Erdelyi, M Yenesew, A AF Endale, Milkyas Ekberg, Annabel Alao, John Patrick Akala, Hoseah M. Ndakala, Albert Sunnerhagen, Per Erdelyi, Mate Yenesew, Abiy TI Anthraquinones of the Roots of Pentas micrantha SO MOLECULES LA English DT Article DE anthraquinone; malaria; Pentas micrantha; Rubiaceae; 5,6-dihydroxylucidin-11-O-methyl ether ID ANTIPLASMODIAL ACTIVITY; DERIVATIVES; LONGIFLORA; RUBIACEAE; QUINONES; MALARIA AB Pentas micrantha is used in the East African indigenous medicine to treat malaria. In the first investigation of this plant, the crude methanol root extract showed moderate antiplasmodial activity against the W2- (3.37 mu g/mL) and D6-strains (4.00 mu g/mL) of Plasmodium falciparum and low cytotoxicity (>450 mu g/mL, MCF-7 cell line). Chromatographic separation of the extract yielded nine anthraquinones, of which 5,6-dihydroxylucidin-11-O-methyl ether is new. Isolation of a munjistin derivative from the genus Pentas is reported here for the first time. The isolated constituents were identified by NMR and mass spectrometric techniques and showed low antiplasmodial activities. C1 [Endale, Milkyas; Ndakala, Albert; Yenesew, Abiy] Univ Nairobi, Dept Chem, Nairobi, Kenya. [Endale, Milkyas; Ekberg, Annabel; Alao, John Patrick; Sunnerhagen, Per; Erdelyi, Mate] Univ Gothenburg, Dept Chem & Mol Biol, SE-41296 Gothenburg, Sweden. [Akala, Hoseah M.] USA, Med Res Unit Kenya, APO, AE 09831 USA. [Erdelyi, Mate] Univ Gothenburg, Swedish NMR Ctr, SE-40530 Gothenburg, Sweden. RP Erdelyi, M (reprint author), Univ Gothenburg, Dept Chem & Mol Biol, SE-41296 Gothenburg, Sweden. EM mate@chem.gu.se; ayenesew@uonbi.ac.ke RI Erdelyi, Mate/A-3686-2009; Sunnerhagen, Per/G-1696-2012 OI Erdelyi, Mate/0000-0003-0359-5970; Sunnerhagen, Per/0000-0002-0967-8729 FU NAPRECA-DAAD; Swedish Research Council (VR) [2012-6124]; International Science Program (ISP, Sweden) [KEN-02] FX M. Endale is thankful to NAPRECA-DAAD for sponsoring his Ph.D. study at the University of Nairobi and acknowledges the support of the Swedish Institute (210/00154/2010) allowing him research visits to the University of Gothenburg. J.P. Alao and P. Sunnerhagen are thankful to the Chemical Biology Platform at the University of Gothenburg, Sweden. M. Erdelyi is thankful for the financial support of the Swedish Research Council (VR #2012-6124). A. Yenesew is grateful to International Science Program (ISP, Sweden) for research grant (KEN-02). NR 26 TC 9 Z9 9 U1 1 U2 13 PU MDPI AG PI BASEL PA POSTFACH, CH-4005 BASEL, SWITZERLAND SN 1420-3049 J9 MOLECULES JI Molecules PD JAN PY 2013 VL 18 IS 1 BP 311 EP 321 DI 10.3390/molecules18010311 PG 11 WC Chemistry, Organic SC Chemistry GA 077MX UT WOS:000314032900022 PM 23271468 ER PT J AU Cheng, YW Zhang, HB Lu, ST Varanasiad, CV Liu, J AF Cheng, Yingwen Zhang, Hongbo Lu, Songtao Varanasiad, Chakrapani V. Liu, Jie TI Flexible asymmetric supercapacitors with high energy and high power density in aqueous electrolytes SO NANOSCALE LA English DT Article ID WALLED CARBON NANOTUBES; ELECTROCHEMICAL CAPACITORS; PERFORMANCE; ELECTRODES; GRAPHENE; COMPOSITES; BATTERIES; NANORODS; BEHAVIOR; STORAGE AB Supercapacitors with both high energy and high power densities are critical for many practical applications. In this paper, we discuss the design and demonstrate the fabrication of flexible asymmetric supercapacitors based on nanocomposite electrodes of MnO2, activated carbon, carbon nanotubes and graphene. The combined unique properties of each of these components enable highly flexible and mechanically strong films that can serve as electrodes directly without using any current collectors or binders. Using these flexible electrodes and a roll-up approach, asymmetric supercapacitors with 2 V working voltage were successfully fabricated. The fabricated device showed excellent rate capability, with 78% of the original capacitance retained when the scan rate was increased from 2 mV s(-1) to 500 mV s(-1). Owing to the unique composite structure, these supercapacitors were able to deliver high energy density (24 W h kg(-1)) under high power density (7.8 kW kg(-1)) conditions. These features could enable supercapacitor based energy storage systems to be very attractive for a variety of critical applications, such as the power sources in hybrid electric vehicles and the back-up powers for wind and solar energy, where both high energy density and high power density are required. C1 [Cheng, Yingwen; Zhang, Hongbo; Lu, Songtao; Varanasiad, Chakrapani V.; Liu, Jie] Duke Univ, Dept Chem, Durham, NC 27708 USA. [Cheng, Yingwen; Liu, Jie] Duke Univ, CEINT, Durham, NC 27708 USA. [Lu, Songtao] Harbin Inst Technol, Dept Chem, Harbin 150001, Peoples R China. [Varanasiad, Chakrapani V.] USA, Res Off, Durham, NC 27703 USA. RP Liu, J (reprint author), Duke Univ, Dept Chem, Durham, NC 27708 USA. EM j.liu@duke.edu RI Cheng, Yingwen/B-2202-2012; Liu, Jie/B-4440-2010 OI Cheng, Yingwen/0000-0002-0778-5504; Liu, Jie/0000-0003-0451-6111 FU Army Research Office (ARO) [W911NF-04-D-0001]; National Science Foundation (NSF); Environmental Protection Agency (EPA) under NSF, Center for the Environmental Implications of Nano-Technology (CEINT) [EF-0830093]; Duke SMIF (Shared Materials Instrumentation Facilities) FX This work is in part supported by a research grant from Army Research Office (ARO) under contract W911NF-04-D-0001 and the National Science Foundation (NSF) and the Environmental Protection Agency (EPA) under NSF Cooperative Agreement EF-0830093, Center for the Environmental Implications of Nano-Technology (CEINT). Any opinions, findings, conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the ARO, NSF or the EPA. This work has not been subjected to EPA review and no official endorsement should be inferred. The authors also acknowledge the support from Duke SMIF (Shared Materials Instrumentation Facilities). NR 41 TC 81 Z9 82 U1 9 U2 236 PU ROYAL SOC CHEMISTRY PI CAMBRIDGE PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND SN 2040-3364 EI 2040-3372 J9 NANOSCALE JI Nanoscale PY 2013 VL 5 IS 3 BP 1067 EP 1073 DI 10.1039/c2nr33136e PG 7 WC Chemistry, Multidisciplinary; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied SC Chemistry; Science & Technology - Other Topics; Materials Science; Physics GA 074HH UT WOS:000313803000033 PM 23254316 ER PT J AU Crum-Cianflone, NF Moore, DJ Letendre, S Roediger, MP Eberly, L Weintrob, A Ganesan, A Johnson, E Del Rosario, R Agan, BK Hale, BR AF Crum-Cianflone, Nancy F. Moore, David J. Letendre, Scott Roediger, Mollie Poehlman Eberly, Lynn Weintrob, Amy Ganesan, Anuradha Johnson, Erica Del Rosario, Raechel Agan, Brian K. Hale, Braden R. TI Low prevalence of neurocognitive impairment in early diagnosed and managed HIV-infected persons SO NEUROLOGY LA English DT Article ID ACTIVE ANTIRETROVIRAL THERAPY; HUMAN-IMMUNODEFICIENCY-VIRUS; NEUROPSYCHOLOGICAL IMPAIRMENT; RISK-FACTORS; ERA; SEROCONVERSION; DISORDERS; ADHERENCE; DEMENTIA; PATTERNS AB Objective: To describe the prevalence of neurocognitive impairment (NCI) among early diagnosed and managed HIV-infected persons (HIV+) compared to HIV-negative controls. Methods: We performed a cross-sectional study among 200 HIV+ and 50 matched HIV-uninfected (HIV-) military beneficiaries. HIV+ patients were categorized as earlier (<6 years of HIV, no AIDS-defining conditions, and CD4 nadir >200 cells/mm(3)) or later stage patients (n = 100 in each group); both groups were diagnosed early and had access to care. NCI was diagnosed using a comprehensive battery of standardized neuropsychological tests. Results: HIV+ patients had a median age of 36 years, 91% were seroconverters (median window of 1.2 years), had a median duration of HIV of 5 years, had a CD4 nadir of 319, had current CD4 of 546 cells/mm(3), and 64% were on highly active antiretroviral therapy (initiated 1.3 years after diagnosis at a median CD4 of 333 cells/mm(3)). NCI was diagnosed among 38 (19%, 95% confidence interval 14%-25%) HIV+ patients, with a similar prevalence of NCI among earlier and later stage patients (18% vs 20%, p = 0.72). The prevalence of NCI among HIV+ patients was similar to HIV- patients. Conclusions: HIV+ patients diagnosed and managed early during the course of HIV infection had a low prevalence of NCI, comparable to matched HIV-uninfected persons. Early recognition and management of HIV infection may be important in limiting neurocognitive impairment. Neurology (R) 2013;80:371-379 C1 [Crum-Cianflone, Nancy F.; Roediger, Mollie Poehlman; Eberly, Lynn; Weintrob, Amy; Ganesan, Anuradha; Johnson, Erica; Del Rosario, Raechel; Agan, Brian K.; Hale, Braden R.] Uniformed Serv Univ Hlth Sci, Infect Dis Clin Res Program, Bethesda, MD 20814 USA. [Crum-Cianflone, Nancy F.; Del Rosario, Raechel; Hale, Braden R.] USN, San Diego Med Ctr, HIV Clin, San Diego, CA 92152 USA. [Crum-Cianflone, Nancy F.; Hale, Braden R.] USN, Hlth Res Ctr, San Diego, CA 92152 USA. [Moore, David J.; Letendre, Scott] Univ Calif San Diego, Hlth Neurobehav Res Program, San Diego, CA 92103 USA. [Roediger, Mollie Poehlman; Eberly, Lynn] Univ Minnesota, Div Biostat, Minneapolis, MN USA. [Weintrob, Amy] Walter Reed Army Med Ctr, Infect Dis Clin, Washington, DC 20307 USA. [Ganesan, Anuradha] Natl Naval Med Ctr, Infect Dis Clin, Bethesda, MD USA. [Johnson, Erica] San Antonio Mil Med Ctr, Infect Dis Serv, San Antonio, TX USA. RP Crum-Cianflone, NF (reprint author), Uniformed Serv Univ Hlth Sci, Infect Dis Clin Res Program, Bethesda, MD 20814 USA. EM nancy.crum@med.navy.mil OI Agan, Brian/0000-0002-5114-1669; Eberly, Lynn/0000-0003-4763-330X FU Infectious Disease Clinical Research Program (IDCRP), a Department of Defense (DoD) program [IDCRP-016]; National Institute of Allergy and Infectious Diseases, NIH [Y1-AI-5072]; Neurobehavioral Health Research Center from the National Institute of Mental Health (UCSD HIV Neurobehavioral Research Center) [P30 MH62512] FX Support for this work (IDCRP-016) was provided by the Infectious Disease Clinical Research Program (IDCRP), a Department of Defense (DoD) program executed through the Uniformed Services University of the Health Sciences. This project has been funded in whole, or in part, with federal funds from the National Institute of Allergy and Infectious Diseases, NIH, under Inter-Agency Agreement Y1-AI-5072. Support was also obtained by the Neurobehavioral Health Research Center from the National Institute of Mental Health (UCSD HIV Neurobehavioral Research Center, P30 MH62512). The content of this publication is the sole responsibility of the authors and does not necessarily reflect the views or policies of the NIH or the Department of Health and Human Services, the DoD, or the Departments of the Army, Navy, or Air Force. Mention of trade names, commercial products, or organizations does not imply endorsement by the US Government. Go to Neurology.org for full disclosures. NR 32 TC 23 Z9 24 U1 1 U2 3 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0028-3878 J9 NEUROLOGY JI Neurology PD JAN PY 2013 VL 80 IS 4 BP 371 EP 379 DI 10.1212/WNL.0b013e31827f0776 PG 9 WC Clinical Neurology SC Neurosciences & Neurology GA 076MQ UT WOS:000313961000015 PM 23303852 ER PT J AU McGraw, LK Out, D Hammermeister, JJ Ohlson, CJ Pickering, MA Granger, DA AF McGraw, Leigh K. Out, Dorothee Hammermeister, Jon J. Ohlson, Carl J. Pickering, Michael A. Granger, Douglas A. TI Nature, correlates, and consequences of stress-related biological reactivity and regulation in Army nurses during combat casualty simulation SO PSYCHONEUROENDOCRINOLOGY LA English DT Article DE Salivary cortisol; Alpha-amylase; Combat casualty stress task; Blood pressure; Heart rate; Age; Gender; Army nurses ID SALIVARY ALPHA-AMYLASE; PSYCHOLOGICAL STRESS; CARE NURSES; CORTISOL; SYSTEM; RESPONSES; DISSOCIATION; PERFORMANCE; INTEGRATION; DISEASE AB This study examined the nature, concomitants, and consequences of stress-related biological reactivity and regulation among Army nurses. Saliva was collected, heart rate (HR) and blood pressure (BP) recorded from 38 Army nurses (74% female; mean age 28.5 years [SD = 6.5]) before, during, and after participation in the Combat Casualty Stress Scenario (CCSS). Saliva was assayed for cortisol and alpha-amylase (sAA). The CCSS simulates emergency combat rescue, employing two simulated combat casualties, aversive body odors, recorded battlefield sounds, and smoke in a low light environment. Participants locate and conduct preliminary assessments of the simulated patients, triage based on injury severity, initiate treatment, and coordinate medical evacuation by radio. Results revealed large magnitude increases in cortisol, sAA, HR, systolic BP and diastolic BP in response to the CCSS, followed by recovery to baseline levels 30 min after the task for all physiological parameters except cortisol. Age, gender, perceived difficulty of the CCSS, and previous nursing experience were associated with individual differences in the magnitude of the physiological responses. Lower levels of performance related to triage and treatment were associated with higher levels of reactivity and slower recovery for some of the physiological measures. The findings raise important questions regarding the utility of integrating measures of the psychobiology of the stress response into training programs designed to prepare first responders to handle highly complex and chaotic rescue situations. Published by Elsevier Ltd. C1 [McGraw, Leigh K.] Joint Base Lewis McChord, Consolidated Educ, Madigan Healthcare Syst, Tacoma, WA 98431 USA. [Out, Dorothee] Leiden Univ, Ctr Child & Family Studies, NL-2300 RA Leiden, Netherlands. [Hammermeister, Jon J.; Ohlson, Carl J.; Pickering, Michael A.] US Mil Acad, Ctr Enhanced Performance, West Point, NY 10996 USA. [Out, Dorothee; Granger, Douglas A.] Johns Hopkins Univ, Ctr Interdisciplinary Salivary Biosci Res, Baltimore, MD USA. RP McGraw, LK (reprint author), Joint Base Lewis McChord, Consolidated Educ, Madigan Healthcare Syst, 9040 Jackson Ave,Bldg 9931B, Tacoma, WA 98431 USA. EM leigh.mcgraw@us.army.mil FU Triservice Nursing Research Program (TSNRP) [HU0001-09-1-TS11]; Rubicon award from the Netherlands Organization for Scientific Research [446-10-026] FX This study was awarded to L.M. by the Triservice Nursing Research Program (TSNRP), Grant Number HU0001-09-1-TS11. The role of TSNRP did not extend beyond financial support. D.O. was supported by a Rubicon award (446-10-026) from the Netherlands Organization for Scientific Research. NR 38 TC 7 Z9 7 U1 0 U2 18 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0306-4530 J9 PSYCHONEUROENDOCRINO JI Psychoneuroendocrinology PD JAN PY 2013 VL 38 IS 1 BP 135 EP 144 DI 10.1016/j.psyneuen.2012.05.009 PG 10 WC Endocrinology & Metabolism; Neurosciences; Psychiatry SC Endocrinology & Metabolism; Neurosciences & Neurology; Psychiatry GA 073RU UT WOS:000313761000013 PM 22710003 ER PT J AU Tompkins, RP Walsh, TA Derenge, MA Kirchner, KW Zhou, S Nguyen, CB Jones, KA Mulholland, G Metzger, R Leach, JH Suvarna, P Tungare, M Shahedipour-Sandvik, F AF Tompkins, Randy P. Walsh, Timothy A. Derenge, Michael A. Kirchner, Kevin W. Zhou, Shuai Nguyen, Cuong B. Jones, Kenneth A. Mulholland, Gregory Metzger, Robert Leach, Jacob H. Suvarna, Puneet Tungare, Mihir Shahedipour-Sandvik, Fatemeh (Shadi) TI HVPE GaN for high power electronic Schottky diodes SO SOLID-STATE ELECTRONICS LA English DT Article DE Gallium nitride; Schottky diode; High power electronics; Hydride vapor phase epitaxy AB Hydride vapor phase epitaxy (HVPE) grown GaN was evaluated for high power Schottky diodes (SDs) because it contains much less carbon and grows much more rapidly than other typical growth methods. The results are encouraging for applications <1000 V in that breakdown voltages (V-B) near this value can be readily obtained with figures of merit (FOM) of approximate to 250 MW/cm(2) that most likely can be improved upon. The properties of the SDs, however, vary dramatically from point to point, and cannot be attributed solely to processing issues. It is much more likely this variation across the wafer can be attributed to material inhomogeneities such as dislocations and point defects. (C) 2012 Elsevier Ltd. All rights reserved. C1 [Tompkins, Randy P.; Walsh, Timothy A.; Derenge, Michael A.; Kirchner, Kevin W.; Zhou, Shuai; Nguyen, Cuong B.; Jones, Kenneth A.] USA, Sensors & Electron Devices Directorate, Res Lab, Adelphi, MD 20783 USA. [Mulholland, Gregory; Metzger, Robert; Leach, Jacob H.] Kyma Technol, Raleigh, NC 27617 USA. [Suvarna, Puneet; Tungare, Mihir; Shahedipour-Sandvik, Fatemeh (Shadi)] SUNY Albany, Coll Nanoscale Sci & Engn, Albany, NY 12203 USA. RP Tompkins, RP (reprint author), USA, Sensors & Electron Devices Directorate, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM randy.tompkins.ctr@mail.mil NR 12 TC 5 Z9 5 U1 0 U2 37 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0038-1101 J9 SOLID STATE ELECTRON JI Solid-State Electron. PD JAN PY 2013 VL 79 BP 238 EP 243 DI 10.1016/j.sse.2012.07.003 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied; Physics, Condensed Matter SC Engineering; Physics GA 071RD UT WOS:000313611000045 ER PT J AU Ratcliffe, TA Hanson, JL Hemmer, PA Hauer, KE Papp, KK Denton, GD AF Ratcliffe, Temple A. Hanson, Janice L. Hemmer, Paul A. Hauer, Karen E. Papp, Klara K. Denton, Gerald D. TI The Required Written History and Physical is Alive, but Not Entirely Well, in Internal Medicine Clerkships SO TEACHING AND LEARNING IN MEDICINE LA English DT Article ID STUDENTS; VOCABULARY; CLINICS; RECORDS; SKILLS AB Background: Effective written communication is a core competency for medical students, but it is unclear whether or how this skill is evaluated in clinical clerkships. Purpose: This study identifies current requirements and practices regarding required written work during internal medicine clerkships. Methods: In 2010, Clerkship Directors of Internal Medicine (CDIM) surveyed its institutional members; one section asked questions about students written work. Results were compared to similar, unpublished CDIM 2001 survey questions. Results: Requirements for student-written work were nearly universal (96% in 2001 and 100% in 2010). Only 23% used structured evaluation forms and 16% reported written work was weighted as a percentage of the final grade, although 72% of respondents reported that written work was factored into global ratings. Conclusions: Despite near universal requirements for student written work, structured evaluation was not commonly performed, raising concern about the validity of factoring these assessments into grades. C1 [Ratcliffe, Temple A.; Hanson, Janice L.; Hemmer, Paul A.; Denton, Gerald D.] Uniformed Serv Univ Hlth Sci, Dept Med, Bethesda, MD 20814 USA. [Hauer, Karen E.] Univ Calif San Francisco, Dept Med, San Francisco, CA USA. [Papp, Klara K.] Case Western Reserve Univ, Sch Med, Ctr Assessment Med Learning, Cleveland, OH USA. RP Ratcliffe, TA (reprint author), Brooke Army Med Ctr, 3551 Roger Brooke Dr Int Med MCHE MDV, Ft Sam Houston, TX 78234 USA. EM temple.ratcliffe@us.af.mil RI Denton, Gerald/J-8562-2012 NR 19 TC 5 Z9 5 U1 0 U2 3 PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD PI ABINGDON PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND SN 1040-1334 J9 TEACH LEARN MED JI Teach. Learn. Med. PD JAN 1 PY 2013 VL 25 IS 1 BP 10 EP 14 DI 10.1080/10401334.2012.741538 PG 5 WC Education, Scientific Disciplines; Health Care Sciences & Services SC Education & Educational Research; Health Care Sciences & Services GA 072OB UT WOS:000313680600004 PM 23330889 ER PT J AU Conway, DG Lyon, RF Heiner, JD AF Conway, Daniel G. Lyon, Regan F. Heiner, Jason D. TI IMAGES IN EMERGENCY MEDICINE Staphylococcal scalded skin syndrome. SO ANNALS OF EMERGENCY MEDICINE LA English DT Editorial Material C1 [Conway, Daniel G.; Lyon, Regan F.; Heiner, Jason D.] Brooke Army Med Ctr, Dept Emergency Med, Ft Sam Houston, TX 78234 USA. RP Conway, DG (reprint author), Brooke Army Med Ctr, Dept Emergency Med, Ft Sam Houston, TX 78234 USA. NR 4 TC 0 Z9 0 U1 0 U2 1 PU MOSBY-ELSEVIER PI NEW YORK PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA SN 0196-0644 J9 ANN EMERG MED JI Ann. Emerg. Med. PD JAN PY 2013 VL 61 IS 1 BP 118 EP + DI 10.1016/j.annemergmed.2012.05.025 PG 2 WC Emergency Medicine SC Emergency Medicine GA 069WY UT WOS:000313469000023 PM 23260687 ER PT J AU McCauley, JW Strassburger, E Patel, P Paliwal, B Ramesh, KT AF McCauley, J. W. Strassburger, E. Patel, P. Paliwal, B. Ramesh, K. T. TI Experimental Observations on Dynamic Response of Selected Transparent Armor Materials SO EXPERIMENTAL MECHANICS LA English DT Article DE Dynamic mechanical tests; Glasses; AlON; Sapphire; High speed photography ID MAGNESIUM ALUMINATE SPINEL; INDENTATION RESPONSE; COMPRESSIVE FAILURE; SAPPHIRE; IMPACT; DAMAGE; ALON AB Structural transparent material systems are critical for many military and civilian applications. Transparent armor systems can consist of a wide variety of glass laminate assemblies with polymeric bonding interfaces and backing as well as the inclusion of polycrystalline ceramic (AlON, spinel) and single crystals (sapphire) as front facing materials. Over the last 20 years as the threats have escalated and become more varied, the challenges for rapidly developing optimized threat specific transparent armor packages have become extremely complex. Ultimate failure of structural ceramics in impact events is a function of the temporal and spatial interaction of the macro-stresses at the macro-, micro- and nano-structural scale, including elastic and inelastic (plastic) deformation, crack nucleation, damage evolution and resulting failure from the macro-scale (top down) and/or from the nano-scale (bottom up). In order to accelerate the development of validated design and predictive performance models, a systematic series of experimental investigations have been carried out on various non-crystalline ceramics (glass), single crystal (sapphire) and polycrystalline ceramics (AlON). The Edge-on Impact (EOI) test coupled with a high-speed Cranz-Schardin film camera has been extensively used on a variety of monolithic and laminated glasses, AlON and crystallographically controlled sapphire single crystals to visualize and quantify stress wave, crack and damage propagation. A modified Kolsky bar technique instrumented with a high speed digital camera has been utilized in an unconfined and confined test sample mode to examine the dynamic deformation and failure of AlON undergoing uniaxial, high strain rate compression. Real time photography has clearly demonstrated the critical influence of defects and post mortem characterization of fragments resulting from these tests have revealed the influence of micro-deformational twining and cleavage down to the nano-scale. Finally, a brief summary of work using ultra-high-speed photography of the impact of conventional projectiles on glass and AlON will be presented. These experimental results will be absolutely critical to help evolve and validate existing models used in computer codes to simulate the impact performance of brittle materials. C1 [McCauley, J. W.; Patel, P.] USA, Res Lab, Aberdeen Proving Ground, MD USA. [Strassburger, E.] Fraunhofer Inst Kurzzeitdynam EMI, Kandern, Germany. [Paliwal, B.; Ramesh, K. T.] Johns Hopkins Univ, Baltimore, MD USA. RP McCauley, JW (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD USA. EM james.w.mccauley.civ@mail.mil; elmar.Strassburger@emi.fraunhofer.de; parimal.j.patel.civ@mail.mil; ramesh@jhu.edu NR 53 TC 15 Z9 15 U1 2 U2 82 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 0014-4851 J9 EXP MECH JI Exp. Mech. PD JAN PY 2013 VL 53 IS 1 SI SI BP 3 EP 29 DI 10.1007/s11340-012-9658-5 PG 27 WC Materials Science, Multidisciplinary; Mechanics; Materials Science, Characterization & Testing SC Materials Science; Mechanics GA 069BA UT WOS:000313408700002 ER PT J AU Swab, JJ Thies, SR Wright, JC Schoenstein, JA Patel, PJ AF Swab, J. J. Thies, S. R. Wright, J. C. Schoenstein, J. A. Patel, P. J. TI Influence of Surface Scratches on the Flexure Strength of Soda-Lime Silicate and Borosilicate Glass SO EXPERIMENTAL MECHANICS LA English DT Article DE Borosilicate glass; Soda-lime-silicate glass; Equibiaxial flexure strength; Scratch behavior; Fracture analysis ID CRACKS; DAMAGE AB Borosilicate (BS) and soda-lime silicate (SLS) glasses are being considered for use as the strike-face in transparent armor systems. This effort examined the effect of surface scratches generated with 1, 5, 10, and 30 N scratching loads on the equibiaxial flexure strength of both glasses including versions of each that had been thermally-tempered. At lower scratch loads there is more lateral cracking associated with the scratches in the BS while the scratches in the SLS predominantly exhibit plastic deformation. At the highest scratch load the damage is dominated by chips and lateral cracking within and along the scratch length. The tempered versions of the SLS appear to have less lateral cracking than the tempered version of the BS glass. In all instances the flexure strength decreases significantly when a 1 N scratch is introduced on the tin surface but when the scratch load increases any additional strength loss is minimal. C1 [Swab, J. J.; Thies, S. R.; Wright, J. C.; Schoenstein, J. A.; Patel, P. J.] USA, Res Lab, Aberdeen, MD USA. RP Swab, JJ (reprint author), USA, Res Lab, Aberdeen, MD USA. EM jeffrey.j.swab.civ@mail.mil NR 22 TC 2 Z9 2 U1 0 U2 22 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 0014-4851 EI 1741-2765 J9 EXP MECH JI Exp. Mech. PD JAN PY 2013 VL 53 IS 1 SI SI BP 91 EP 96 DI 10.1007/s11340-012-9674-5 PG 6 WC Materials Science, Multidisciplinary; Mechanics; Materials Science, Characterization & Testing SC Materials Science; Mechanics GA 069BA UT WOS:000313408700008 ER PT J AU Maschal, RA Young, SS Reynolds, JP Krapels, K Fanning, J Corbin, T AF Maschal, Robert A., Jr. Young, S. Susan Reynolds, Joseph P. Krapels, Keith Fanning, Jonathan Corbin, Ted TI New Image Quality Assessment Algorithms for CFA Demosaicing SO IEEE SENSORS JOURNAL LA English DT Article DE Color filter array (CFA) demosaicing; edge slope measure; false color measure; no-reference quality assessment ID COLOR; INTERPOLATION AB To address the frequent lack of a reference image or ground truth when performance testing Bayer pattern color filter array demosaicing algorithms, we propose two new no-reference quality assessment algorithms. These algorithms provide a relative comparison of two demosaicing algorithms by measuring the presence of two common artifacts, zippering and false coloring, in their output images. The first algorithm, the edge slope measure, tests the overall sharpness of each of the three color channels, thus estimating the relative edge reconstruction accuracy of each demosaicing algorithm. The second algorithm, the false color measure, estimates deviations from the established constant color difference image model and performs on green-red and green-blue color difference planes, therefore estimating the red and blue channel reconstruction of each demosaicing algorithm. We evaluate and rank common demosaicing algorithms using these new algorithms. Furthermore, we present real image examples for subjective evaluation to justify the rankings suggested by the new quality assessment algorithms. C1 [Maschal, Robert A., Jr.] Univ Maryland, College Pk, MD 20742 USA. [Young, S. Susan] USA, Res Lab, Adelphi, MD 20783 USA. [Reynolds, Joseph P.; Krapels, Keith; Fanning, Jonathan; Corbin, Ted] Night Vis & Elect Sensors Directorate, Ft Belvoir, VA 22060 USA. RP Maschal, RA (reprint author), Univ Maryland, College Pk, MD 20742 USA. EM robertmaschal@gmail.com; shiqiong.susan.young@us.army.mil; joseph.p.reynolds.civ@mail.mil; keith.a.krapels.civ@mail.mil; jonathan.fanning@nvl.army.mil; ted.corbin.civ@mail.mil NR 23 TC 2 Z9 2 U1 1 U2 16 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 1530-437X J9 IEEE SENS J JI IEEE Sens. J. PD JAN PY 2013 VL 13 IS 1 BP 371 EP 378 DI 10.1109/JSEN.2012.2216371 PG 8 WC Engineering, Electrical & Electronic; Instruments & Instrumentation; Physics, Applied SC Engineering; Instruments & Instrumentation; Physics GA 073AL UT WOS:000313715500001 ER PT J AU Sukhai, MA Prabha, S Hurren, R Rutledge, AC Lee, AY Sriskanthadevan, S Sun, H Wang, XM Skrtic, M Seneviratne, A Cusimano, M Jhas, B Gronda, M MacLean, N Cho, EE Spagnuolo, PA Sharmeen, S Gebbia, M Urbanus, M Eppert, K Dissanayake, D Jonet, A Dassonville-Klimpt, A Li, XM Datti, A Ohashi, PS Wrana, J Rogers, I Sonnet, P Ellis, WY Corey, SJ Eaves, C Minden, MD Wang, JCY Dick, JE Nislow, C Giaever, G Schimmer, AD AF Sukhai, Mahadeo A. Prabha, Swayam Hurren, Rose Rutledge, Angela C. Lee, Anna Y. Sriskanthadevan, Shrivani Sun, Hong Wang, Xiaoming Skrtic, Marko Seneviratne, Ayesh Cusimano, Maria Jhas, Bozhena Gronda, Marcela MacLean, Neil Cho, Eunice E. Spagnuolo, Paul A. Sharmeen, Sumaiya Gebbia, Marinella Urbanus, Malene Eppert, Kolja Dissanayake, Dilan Jonet, Alexia Dassonville-Klimpt, Alexandra Li, Xiaoming Datti, Alessandro Ohashi, Pamela S. Wrana, Jeff Rogers, Ian Sonnet, Pascal Ellis, William Y. Corey, Seth J. Eaves, Connie Minden, Mark D. Wang, Jean C. Y. Dick, John E. Nislow, Corey Giaever, Gun Schimmer, Aaron D. TI Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors SO JOURNAL OF CLINICAL INVESTIGATION LA English DT Article ID DIPEPTIDYL PEPTIDASE-I; LEUCINE METHYL-ESTER; CATHEPSIN-B RELEASE; STEM-CELLS; CYTOTOXIC LYMPHOCYTES; QINGHAOSU ARTEMISININ; ANTIMALARIAL ACTIVITY; INTEGRAL MEMBRANE; DEATH PATHWAY; PHASE-II AB Despite efforts to understand and treat acute myeloid. leukemia (AML), there remains a need for more comprehensive therapies to prevent AML-associated relapses. To identify new therapeutic strategies for AML, we screened a library of on- and off-patent drugs and identified the antimalarial agent mefloquine as a compound that selectively kills AML cells and AML stem cells in a panel of leukemia cell lines and in mice. Using a yeast genome-wide functional screen for mefloquine sensitizers, we identified genes associated with the yeast vacuole, the homolog of the mammalian lysosome. Consistent with this, we determined that mefloquine disrupts lysosomes, directly permeabilizes the lysosome membrane, and releases cathepsins into the cytosol. Knockdown of the lysosomal membrane proteins LAMP1 and LAMP2 resulted in decreased cell viability, as did treatment of AML cells with known lysosome disrupters. Highlighting a potential therapeutic rationale for this strategy, leukemic cells had significantly larger lysosomes compared with normal cells, and leukemia-initiating cells overexpressed lysosomal biogenesis genes. These results demonstrate that lysosotnal disruption preferentially targets AML cells and AML progenitor cells, providing a rationale for testing lysosomal disruption as a novel therapeutic strategy for AML. C1 [Sukhai, Mahadeo A.; Prabha, Swayam; Hurren, Rose; Rutledge, Angela C.; Sriskanthadevan, Shrivani; Sun, Hong; Wang, Xiaoming; Skrtic, Marko; Seneviratne, Ayesh; Cusimano, Maria; Jhas, Bozhena; Gronda, Marcela; MacLean, Neil; Cho, Eunice E.; Spagnuolo, Paul A.; Sharmeen, Sumaiya; Eppert, Kolja; Li, Xiaoming; Minden, Mark D.; Wang, Jean C. Y.; Dick, John E.; Schimmer, Aaron D.] Univ Hlth Network, Princess Margaret Hosp, Ontario Canc Inst, Toronto, ON M5G 2M9, Canada. [Gebbia, Marinella; Urbanus, Malene; Nislow, Corey; Giaever, Gun] Univ Toronto, Dept Mol Genet, Donnelly Ctr Cellular & Biomol Res, Toronto, ON, Canada. [Dissanayake, Dilan; Ohashi, Pamela S.] Campbell Family Inst Breast Canc Res, Toronto, ON, Canada. [Jonet, Alexia; Dassonville-Klimpt, Alexandra; Sonnet, Pascal] Univ Picardie, UFR Pharm, Lab Glucides, CNRS,FRE 3517, Amiens, France. [Datti, Alessandro; Wrana, Jeff; Rogers, Ian] Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Toronto, ON M5G 1X5, Canada. [Datti, Alessandro] Univ Perugia, Dept Expt Med & Biochem Sci, I-06100 Perugia, Italy. [Ellis, William Y.] Walter Reed Army Inst Res, Dept Chem Informat, Div Expt Therapeut, Silver Spring, MD USA. [Corey, Seth J.] Northwestern Univ, Sch Med, Dept Pediat, Chicago, IL 60611 USA. [Corey, Seth J.] Northwestern Univ, Sch Med, Dept Cell & Mol Biol, Chicago, IL USA. [Eaves, Connie] British Columbia Canc Agcy, Terry Fox Lab, Vancouver, BC V5Z 1L3, Canada. [Wang, Jean C. Y.] Univ Toronto, Dept Med, Toronto, ON, Canada. RP Schimmer, AD (reprint author), Univ Hlth Network, Princess Margaret Hosp, Ontario Canc Inst, Rm 9-516,610 Univ Ave, Toronto, ON M5G 2M9, Canada. EM aaron.schimmer@utoronto.ca RI Wrana, Jeffrey/F-8857-2013; Rogers, Ian /D-5092-2015; di Ronza, Alberto/H-7674-2016; OI Rogers, Ian /0000-0001-8466-1225; di Ronza, Alberto/0000-0002-9813-5143; Datti, Alessandro/0000-0001-6824-7382; Nislow, Corey/0000-0002-4016-8874 FU Leukemia and Lymphoma Society; International Myeloma Foundation; Canadian Stem Cell Network; Ontario Institute of Cancer Research; Ontario Ministry of Research and Innovation; Ministry of Health and Long-Term Care in the Province of Ontario; Canadian Institutes of Health Research (CIHR); Terry Fox Foundation; National Human Genome Research Institute (NHGRI); Canadian Cancer Society [020380] FX We thank Jill Flewelling for administrative assistance and help in preparation of the manuscript. This work was supported by the Leukemia and Lymphoma Society, the International Myeloma Foundation, the Canadian Stem Cell Network, the Ontario Institute of Cancer Research through funding from the Ontario Ministry of Research and Innovation, and the Ministry of Health and Long-Term Care in the Province of Ontario, the Canadian Institutes of Health Research (CIHR), and the Terry Fox Foundation. M.A. Sukhai is a CIHR Post-Doctoral Fellow and an Ontario Ministry of Research and Innovation Post-Doctoral Fellow. G. Giaever and C. Nislow are supported by a grant from the National Human Genome Research Institute (NHGRI) and a grant from the Canadian Cancer Society (no. 020380). A.D. Schimmer is a Leukemia and Lymphoma Society Scholar in Clinical Research. NR 72 TC 25 Z9 25 U1 1 U2 21 PU AMER SOC CLINICAL INVESTIGATION INC PI ANN ARBOR PA 35 RESEARCH DR, STE 300, ANN ARBOR, MI 48103 USA SN 0021-9738 J9 J CLIN INVEST JI J. Clin. Invest. PD JAN PY 2013 VL 123 IS 1 BP 315 EP 328 DI 10.1172/JCI64180 PG 14 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA 071MV UT WOS:000313598500035 PM 23202731 ER PT J AU Merkle, LD Ter-Gabrielyan, N AF Merkle, Larry D. Ter-Gabrielyan, Nikolay TI Er3+ in Sc2O3 and Y2O3: Spectroscopy to elucidate laser behavior SO JOURNAL OF LUMINESCENCE LA English DT Article; Proceedings Paper CT 16th International conference on luminescence and optical spectroscopy of condensed matter CY JUN 27-JUL 01, 2011 CL Ann Arbor, MI DE Erbium; Yttria; Scandia; Absorption; Stimulated emission ID Y3AL5O12; RANGE AB Er:Sc2O3 exhibits spectroscopic properties that give surprising cryogenic laser behavior (particularly broad zero-line absorption, and a switch to a shorter laser wavelength for temperatures above 110 K). We find that spectroscopic comparison of this material with Er:Y2O3 clarifies the subtle features responsible for this laser behavior. Published by Elsevier B.V. C1 [Merkle, Larry D.; Ter-Gabrielyan, Nikolay] USA, Res Lab, RDRL SEE M, Adelphi, MD 20783 USA. RP Merkle, LD (reprint author), USA, Res Lab, RDRL SEE M, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM larry.d.merkle.civ@mail.mil NR 9 TC 4 Z9 4 U1 1 U2 18 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0022-2313 EI 1872-7883 J9 J LUMIN JI J. Lumines. PD JAN PY 2013 VL 133 BP 254 EP 256 DI 10.1016/j.jlumin.2011.12.017 PG 3 WC Optics SC Optics GA 070AK UT WOS:000313478000052 ER PT J AU Williams, EH Schreifels, JA Rao, MV Davydov, AV Oleshko, VP Lin, NJ Steffens, KL Krylyuk, S Bertness, KA Manocchi, AK Koshka, Y AF Williams, Elissa H. Schreifels, John A. Rao, Mulpuri V. Davydov, Albert V. Oleshko, Vladimir P. Lin, Nancy J. Steffens, Kristen L. Krylyuk, Sergiy Bertness, Kris A. Manocchi, Amy K. Koshka, Yaroslav TI Selective streptavidin bioconjugation on silicon and silicon carbide nanowires for biosensor applications SO JOURNAL OF MATERIALS RESEARCH LA English DT Article ID RAY PHOTOELECTRON-SPECTROSCOPY; SURFACES; OXIDE; FUNCTIONALIZATION; INTERFACES; MONOLAYERS; GROWTH; FILM AB A functionalization method for the specific and selective immobilization of the streptavidin (SA) protein on semiconductor nanowires (NWs) was developed. Silicon (Si) and silicon carbide (SiC) NWs were functionalized with 3-aminopropyltriethoxysilane (APTES) and subsequently biotinylated for the conjugation of SA. Existence of a thin native oxide shell on both Si and SiC NWs enabled efficient binding of APTES with the successive attachment of biotin and SA as was confirmed with x-ray photoelectron spectroscopy, high-resolution transmission electron microscopy, and atomic force microscopy. Fluorescence microscopy demonstrated nonspecific, electrostatic binding of the SA and the bovine serum albumin (BSA) proteins to APTES-coated NWs. Inhibition of nonspecific BSA binding and enhancement of selective SA binding were achieved on biotinylated NWs. The biofunctionalized NWs have the potential to be used as biosensing platforms for the specific and selective detection of proteins. C1 [Williams, Elissa H.; Schreifels, John A.] George Mason Univ, Dept Chem & Biochem, Fairfax, VA 22030 USA. [Williams, Elissa H.; Rao, Mulpuri V.] George Mason Univ, Dept Elect & Comp Engn, Fairfax, VA 22030 USA. [Williams, Elissa H.; Davydov, Albert V.; Oleshko, Vladimir P.; Lin, Nancy J.; Steffens, Kristen L.; Krylyuk, Sergiy] NIST, Mat Measurement Lab, Gaithersburg, MD 20899 USA. [Krylyuk, Sergiy] Univ Maryland, Inst Res Elect & Appl Phys, College Pk, MD 20742 USA. [Bertness, Kris A.] NIST, Phys Measurement Lab, Boulder, CO 80305 USA. [Manocchi, Amy K.] USA, Sensors & Elect Devices Directorate, Res Lab, Adelphi, MD 20783 USA. [Koshka, Yaroslav] Mississippi State Univ, Dept Elect & Comp Engn, Mississippi State, MS 39762 USA. RP Williams, EH (reprint author), George Mason Univ, Dept Chem & Biochem, Fairfax, VA 22030 USA. EM ewilliah@gmu.edu; davydov@nist.gov RI Davydov, Albert/F-7773-2010; Oleshko, Vladimir/A-6250-2014 OI Davydov, Albert/0000-0003-4512-2311; Oleshko, Vladimir/0000-0003-0538-2354 FU National Science Foundation [ECCS-0901712]; NIST [SB134110SE0579, SB134111SE0814]; U.S. Army Research Laboratory FX The authors are appreciative of the helpful discussions with Dr. Marlon L. Walker (Material Measurement Laboratory, NIST) and Dr. Rebecca A. Zangmeister (Material Measurement Laboratory, NIST) as well as the assistance of Dr. Anthony G. Birdwell (Sensors & Electronic Devices Directorate, Army Research Laboratory). EHW, MVR, and JAS gratefully acknowledge the financial support of the National Science Foundation (Grant No. ECCS-0901712); VPO gratefully acknowledges the financial support from NIST under contracts SB134110SE0579 and SB134111SE0814. AKM was supported by a contractual appointment to the U.S. Army Research Laboratory Postdoctoral Fellowship Program administered by Oak Ridge Associated Universities. NR 32 TC 9 Z9 9 U1 2 U2 55 PU CAMBRIDGE UNIV PRESS PI NEW YORK PA 32 AVENUE OF THE AMERICAS, NEW YORK, NY 10013-2473 USA SN 0884-2914 J9 J MATER RES JI J. Mater. Res. PD JAN PY 2013 VL 28 IS 1 BP 68 EP 77 DI 10.1557/jmr.2012.283 PG 10 WC Materials Science, Multidisciplinary SC Materials Science GA 071JW UT WOS:000313589600011 ER PT J AU Doornbos, K Sumrandee, C Ruang-Areerate, T Baimai, V Trinachartvanit, W Ahantarig, A AF Doornbos, Kathryn Sumrandee, Chalao Ruang-Areerate, Toon Baimai, Visut Trinachartvanit, Wachareeporn Ahantarig, Arunee TI Rickettsia sp Closely Related to Rickettsia raoultii (Rickettsiales: Rickettsiaceae) in an Amblyomma helvolum (Acarina: Ixodidae) Tick From a Varanus salvator (Squamata: Varanidae) in Thailand SO JOURNAL OF MEDICAL ENTOMOLOGY LA English DT Article DE Amblyomma helvolum; Varanus salvator; tick; Rickettsia raoultii ID FEVER GROUP RICKETTSIAE; SPOTTED-FEVER; PHYLOGENETIC ANALYSIS; AUSTRALIA; REPTILES; HONEI; DNA AB An engorged female Amblyomma helvolum Koch tick was removed from an adult Varanus salvator Laurenti lizard during field collection in Thailand. After using polymerase chain reaction to amplify three genes (16S rDNA, gltA, and OmpA), we discovered the presence of a Rickettsia sp. of the Spotted Fever Group. Phylogenetic analysis revealed that this Rickettsia sp. is closely related to Rickettsia raoultii Mediannikov. Therefore, we report herein for the first time the detection of a novel Spotted Fever Group Rickettsia in an Amblyomma helvolum from a Varanus salvator in Thailand. C1 [Doornbos, Kathryn; Sumrandee, Chalao; Baimai, Visut; Trinachartvanit, Wachareeporn; Ahantarig, Arunee] Mahidol Univ, Fac Sci, Dept Biol, Bangkok 10400, Thailand. [Ruang-Areerate, Toon] Armed Forces Res Inst Med Sci, Div Res, Epidemiol Sect, Bangkok 10400, Thailand. [Baimai, Visut; Ahantarig, Arunee] Mahidol Univ Salaya, Ctr Excellence Vectors & Vector Borne Dis, Fac Sci, Nakhon Pathom 73170, Thailand. RP Ahantarig, A (reprint author), Mahidol Univ, Fac Sci, Dept Biol, Rama 6 Rd, Bangkok 10400, Thailand. EM arunee.aha@mahidol.ac.th OI Doornbos, Kathryn/0000-0003-2488-1036 FU Faculty of Science, Mahidol University, Thailand [SCY52-03, SCM55-004]; Thailand Research Fund; Office of the Higher Education Commission; Mahidol University Research grant [SCJV1099000737]; Thanphuying Viraya Chavakul Foundation for Medical Armed Forces Research Grant; Thailand-United States Education Foundation; U.S. Department of State FX We thank Gail S. Baker for her support and advice given to Kathryn Doornbos. Additionally, we thank Juntima Chanprasert for her useful comments and technical support. This work was supported by researched grants from the Faculty of Science, Mahidol University, Thailand (SCY52-03 and SCM55-004), the Thailand Research Fund and Office of the Higher Education Commission and a Mahidol University Research grant (SCJV1099000737). Part of this work (T. R.) was also supported by Thanphuying Viraya Chavakul Foundation for Medical Armed Forces Research Grant (2010). Kathryn Doornbos was supported by the Thailand-United States Education Foundation and the U.S. Department of State, which provided partial support through a Fulbright Fellowship. NR 22 TC 6 Z9 6 U1 3 U2 12 PU ENTOMOLOGICAL SOC AMER PI LANHAM PA 10001 DEREKWOOD LANE, STE 100, LANHAM, MD 20706-4876 USA SN 0022-2585 J9 J MED ENTOMOL JI J. Med. Entomol. PD JAN PY 2013 VL 50 IS 1 BP 217 EP 220 DI 10.1603/ME12010 PG 4 WC Entomology; Veterinary Sciences SC Entomology; Veterinary Sciences GA 071EV UT WOS:000313570600029 PM 23427674 ER PT J AU Sago, CE Labuda, CS AF Sago, Carrie E. Labuda, Craig S. TI Diagnostic Imaging in a Patient With an Acute Knee Injury SO JOURNAL OF ORTHOPAEDIC & SPORTS PHYSICAL THERAPY LA English DT Editorial Material C1 [Sago, Carrie E.] 3rd Brigade Combat Team, Airborne Div 82, Ft Bragg, NC USA. [Labuda, Craig S.] Womack Army Med Ctr, Dept Radiol, Ft Bragg, NC USA. RP Sago, CE (reprint author), 3rd Brigade Combat Team, Airborne Div 82, Ft Bragg, NC USA. NR 0 TC 0 Z9 0 U1 0 U2 2 PU J O S P T, PI ALEXANDRIA PA 1111 NORTH FAIRFAX ST, STE 100, ALEXANDRIA, VA 22314-1436 USA SN 0190-6011 J9 J ORTHOP SPORT PHYS JI J. Orthop. Sports Phys. Ther. PD JAN PY 2013 VL 43 IS 1 BP 30 EP 30 DI 10.2519/jospt.2013.0402 PG 1 WC Orthopedics; Rehabilitation; Sport Sciences SC Orthopedics; Rehabilitation; Sport Sciences GA 070UV UT WOS:000313539000006 PM 23277192 ER PT J AU Lew, HS Main, JA Robert, SD Sadek, F Chiarito, VP AF Lew, H. S. Main, Joseph A. Robert, Stephen D. Sadek, Fahim Chiarito, Vincent P. TI Performance of Steel Moment Connections under a Column Removal Scenario. I: Experiments SO JOURNAL OF STRUCTURAL ENGINEERING-ASCE LA English DT Article DE Buildings; Connections; Full-scale tests; Progressive collapse; Seismic design; Steel structures AB This paper presents an experimental study of two full-scale steel beam-column assemblies, each comprising three columns and two beams, to (1) define their response characteristics under a column-removal scenario, including the capacity of the beams and their connections to carry loads through catenary action, and (2) provide experimental data for validation of beam-to-column connection models for assessing the robustness of structural systems. The assemblies represent portions of the exterior moment-resisting frames of two 10-story steel-frame buildings. One test specimen had welded unreinforced flange, bolted web connections, and the other had reduced beamesection connections. When subjected to monotonically increasing vertical displacement of the unsupported center column, both specimens exhibited an initial elastic response dominated by flexure. With increased vertical displacement, the connections yielded, and axial tension developed in the beams. The axial tension in the beams increased until the connections failed under combined bending and axial stresses. The test results show that the rotational capacities of both connections under monotonic column displacement are about twice as large as those based on seismic-test data. DOI: 10.1061/(ASCE)ST.1943-541X.0000618. (C) 2013 American Society of Civil Engineers. C1 [Robert, Stephen D.; Chiarito, Vincent P.] USA, Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. [Main, Joseph A.; Sadek, Fahim] NIST, Engn Lab, Struct Grp, Gaithersburg, MD 20899 USA. RP Main, JA (reprint author), NIST, Engn Lab, Struct Grp, 100 Bur Dr,Stop 8611, Gaithersburg, MD 20899 USA. EM hsl@nist.gov; joseph.main@nist.gov; stephen.d.robert@erdc.usace.army.mil; fahim.sadek@nist.gov; vincent.p.chiarito@erdc.usace.army.mil FU National Institute of Standards and Technology; American Institute of Steel Construction; Air Force Research Laboratory; Defense Threat Reduction Agency FX This experimental study was conducted at the Engineer Research and Development Center of the U.S. Army Corps of Engineers and was supported by the National Institute of Standards and Technology, the American Institute of Steel Construction, the Air Force Research Laboratory, and the Defense Threat Reduction Agency. NR 19 TC 14 Z9 17 U1 4 U2 37 PU ASCE-AMER SOC CIVIL ENGINEERS PI RESTON PA 1801 ALEXANDER BELL DR, RESTON, VA 20191-4400 USA SN 0733-9445 J9 J STRUCT ENG-ASCE JI J. Struct. Eng.-ASCE PD JAN PY 2013 VL 139 IS 1 BP 98 EP 107 DI 10.1061/(ASCE)ST.1943-541X.0000618 PG 10 WC Construction & Building Technology; Engineering, Civil SC Construction & Building Technology; Engineering GA 069JI UT WOS:000313431200010 ER PT J AU Kragh, JF Antonio, JS Simmons, JW Mace, JE Stinner, DJ White, CE Fang, R Aden, JK Hsu, JR Eastridge, BJ Jenkins, DH Ritchie, JD Hardin, MO Ritenour, AE Wade, CE Blackbourne, LH AF Kragh, John F., Jr. San Antonio, James Simmons, John W. Mace, James E. Stinner, Daniel J. White, Christopher E. Fang, Raymond Aden, James K. Hsu, Joseph R. Eastridge, Brian J. Jenkins, Donald H. Ritchie, John D. Hardin, Mark O. Ritenour, Amber E. Wade, Charles E. Blackbourne, Lorne H. TI Compartment syndrome performance improvement project is associated with increased combat casualty survival SO JOURNAL OF TRAUMA AND ACUTE CARE SURGERY LA English DT Article DE Health care; quality control; ischemia; trauma system ID MAJOR LIMB TRAUMA; TOURNIQUET USE AB BACKGROUND: In 2008, we showed that incomplete or delayed extremity fasciotomies were associated with mortality and muscle necrosis in war casualties with limb injury. Subsequently, we developed an education program focused on surgeon knowledge gaps regarding the diagnosis of compartment syndrome and prophylactic fasciotomy. The program included educational alerts, classroom training, video instruction, and a research publication. We compared casualty data before and after the program implementation to determine whether the education altered outcomes. METHODS: Similar to the previous study, a case series was made from combat casualty medical records. Casualties were US military servicemen with fasciotomies performed in Iraq, Afghanistan, or Germany between two periods (periods 1 and 2). RESULTS: In both periods, casualty demographics were similar. Most fasciotomies were performed to the lower leg and forearm. Period 1 had 336 casualties with 643 fasciotomies, whereas Period 2 had 268 casualties with 1,221 fasciotomies (1.9 vs. 4.6 fasciotomies per casualty, respectively; p < 0.0001). The mortality rate decreased in Period 2 (3%, 8 of 268 casualties) from Period 1 (8%, 26 of 336 casualties; p = 0.0125). Muscle excision and major amputation rates were similar in both periods (p > 0.05). Rates of casualties with revision fasciotomy decreased to 8% in Period 2, (22 of 268 casualties) versus 15% in Period 1 (51 of 336 casualties; p = 0.009). CONCLUSION: Combat casualty care following implementation of a fasciotomy education program was associated with improved survival, higher fasciotomy rates, and fewer revisions. Because delayed fasciotomy rates were unchanged, further effort to educate providers may be indicated. (J Trauma Acute Care Surg. 2013;74: 259-263. Copyright (C) 2013 by Lippincott Williams & Wilkins) C1 [Kragh, John F., Jr.; San Antonio, James; Simmons, John W.; Mace, James E.; Stinner, Daniel J.; White, Christopher E.; Aden, James K.; Hsu, Joseph R.; Eastridge, Brian J.; Ritchie, John D.; Hardin, Mark O.; Blackbourne, Lorne H.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. [White, Christopher E.] Univ Texas Hlth, Dept Surg, Houston, TX USA. [White, Christopher E.] Univ Texas Hlth, Ctr Translat Injury Res, Houston, TX USA. [Kragh, John F., Jr.] Uniformed Serv Univ Hlth Sci, F Edward Hebert Sch Med, Bethesda, MD 20814 USA. [Fang, Raymond] Landstuhl Reg Med Ctr, Landstuhl, Germany. [Jenkins, Donald H.] Mayo Clin, Div Trauma Crit Care & Gen Surg, Dept Surg, Rochester, MN USA. [Ritenour, Amber E.] Irwin Army Community Hosp, Ft Riley, KS USA. RP Kragh, JF (reprint author), USA, Inst Surg Res, 3698 Chambers Pass,Bldg BHT2,Room 222-4, Ft Sam Houston, TX 78234 USA. EM john.kragh1@us.army.mil OI Stinner, Daniel/0000-0002-8981-6262 FU US Army; US government; US Army Institute of Surgical Research funds FX J.K.F. and co-investigators consult at no cost to numerous tourniquet inventors, patent holders, makers, trainers, doctrinaires, logisticians, and users. Sources of support include internal funding from the US Army and US government for salaries. Financial disclosures that might relate to this article include the following: J.K.F. is an employee of the US government and has consulted at no cost with Composite Resources Inc., Delfi Medical Innovations Inc., North American Rescue Products LLC, H & H Associates Inc., Blackhawk Products Group, and Hemaclear. He has received honoraria for work for the Food and Drug Administration and for the nonprofit Musculoskeletal Transplant Foundation. Funding of this project was with internal US Army Institute of Surgical Research funds and not from any of the following organizations: National Institutes of Health; Wellcome Trust; Howard Hughes Medical Institute, or others. NR 10 TC 8 Z9 8 U1 1 U2 8 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 2163-0755 J9 J TRAUMA ACUTE CARE JI J. Trauma Acute Care Surg. PD JAN PY 2013 VL 74 IS 1 BP 259 EP 263 DI 10.1097/TA.0b013e31826fc71c PG 5 WC Critical Care Medicine; Surgery SC General & Internal Medicine; Surgery GA 071VI UT WOS:000313623300059 PM 23147175 ER PT J AU Berry-Caban, CS Ee, J Ingram, V Berry, CE Kim, EH AF Berry-Caban, Cristobal S. Ee, Juliana Ingram, Victoria Berry, Carlos E. Kim, Eugene H. TI Synthetic Cannabinoid Overdose in a 20-Year-Old Male US Soldier SO SUBSTANCE ABUSE LA English DT Article DE Drug use; Spice; synthetic cannabinoid; US soldiers AB Popularity of synthetic cannabinoids among US military service members has risen over the last several years, leading to an increase in hospitalizations and legal actions stemming from its use and possession. Although synthetic cannabinoids, collectively referred to as Spice, are similar in structure to the active metabolites found in cannabis, significant concerns exist regarding the severity of short- and long-term medical and psychiatric sequelae. This article presents a case, in which a patient experienced severe medical and psychiatric symptoms far exceeding the severity and duration typically resulting from cannabis use. C1 [Berry-Caban, Cristobal S.] Womack Army Med Ctr, Clin Invest Serv, Ft Bragg, NC 28301 USA. [Ee, Juliana; Ingram, Victoria; Kim, Eugene H.] Womack Army Med Ctr, Dept Behav Hlth, Ft Bragg, NC 28301 USA. [Berry, Carlos E.] Tuscaloosa VA Med Ctr, Mental Hlth Serv Line, Tuscaloosa, AL USA. RP Berry-Caban, CS (reprint author), Womack Army Med Ctr, Clin Invest Serv, Ft Bragg, NC 28301 USA. EM cris.berrycaban@us.army.mil NR 8 TC 10 Z9 11 U1 0 U2 5 PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD PI ABINGDON PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND SN 0889-7077 J9 SUBST ABUS JI Subst. Abus. PD JAN 1 PY 2013 VL 34 IS 1 SI SI BP 70 EP 72 DI 10.1080/08897077.2012.677754 PG 3 WC Substance Abuse SC Substance Abuse GA 072KL UT WOS:000313669700009 PM 23327506 ER PT J AU Gerhardt, RT Strandenes, G Cap, AP Rentas, FJ Glassberg, E Mott, J Dubick, MA Spinella, PC AF Gerhardt, Robert T. Strandenes, Geir Cap, Andrew P. Rentas, Francisco J. Glassberg, Elon Mott, Jeff Dubick, Michael A. Spinella, Philip C. CA THOR Network Grp RemTORN Study Grp TI Remote damage control resuscitation and the Solstrand Conference: defining the need, the language, and a way forward SO TRANSFUSION LA English DT Article ID COMBAT CASUALTY CARE; BLOOD-TRANSFUSIONS STRATEGIES; RANDOMIZED CONTROLLED-TRIAL; I TRAUMA CENTER; LAST 60 YEARS; KNOWLEDGE TRANSLATION; EMERGENCY-MEDICINE; EARLY COAGULOPATHY; PREHOSPITAL TIME; RESEARCH AGENDA AB Damage control resuscitation (DCR) is emerging as a standard practice in civilian and military trauma care. Primary objectives include resolution of immediate life threats followed by optimization of physiological status in the perioperative period. To accomplish this, DCR employs a unique hypotensivehemostatic resuscitation strategy that avoids traditional crystalloid intravenous fluids in favor of early blood component use in ratios mimicking whole blood. The presence of uncontrolled major hemorrhage (UMH) coupled with a delay in access to hemostatic surgical intervention remains a primary contributor to preventable death in both combat and in many domestic settings, including rural areas and disaster sites. As a result, civilian and military emergency care leaders throughout the world have sought a means to project DCR principles forward of the traditional trauma resuscitation bay, into such remote environments as disaster scenes, rural health facilities, and the contemporary battlefield. After reflecting on experiences from past conflicts, defining current capability gaps, and examining available and potential solutions, a strategy for remote damage control resuscitation (RDCR) has been proposed. In order for RDCR to progress from concept to clinical strategy, it will be necessary to define existing gaps in knowledge and clinical capability; develop a lexicon so that investigators and operators may understand each other; establish coherent research and development agendas; and execute comprehensive investigations designed to predict, diagnose, and mitigate the consequences of hemorrhagic shock and acute traumatic coagulopathy before they become irreversible. This article seeks to introduce the concept of RDCR; to reinforce the importance of identifying and optimally managing UMH and the resulting shock state as part of a comprehensive approach to out-of-hospital stabilization and en route care; and to propose investigational strategies to enable the development and broad implementation of RDCR principles. C1 USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. San Antonio Mil Med Ctr, Dept Emergency Med, Ft Sam Houston, TX USA. San Antonio Mil Med Ctr, Dept Surg, Ft Sam Houston, TX USA. USA, Med Dept Ctr & Sch, Ctr Predeployment Med, Ft Sam Houston, TX USA. Norwegian Special Operat Commando, Bergen, Norway. Armed Serv Blood Program Off, Falls Church, VA USA. Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA. RP Gerhardt, RT (reprint author), USAISR, 3698 Chambers Pass, Ft Sam Houston, TX 78234 USA. EM robert.gerhardt@us.army.mil NR 65 TC 20 Z9 20 U1 0 U2 10 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0041-1132 J9 TRANSFUSION JI Transfusion PD JAN PY 2013 VL 53 SU 1 SI SI BP 9S EP 16S DI 10.1111/trf.12030 PG 8 WC Hematology SC Hematology GA 071SR UT WOS:000313615000003 PM 23301981 ER PT J AU Sailliol, A Martinaud, C Cap, AP Civadier, C Clavier, B Deshayes, AV Mendes, AC Pouget, T Demazeau, N Chueca, M Martelet, FR Ausset, S AF Sailliol, Anne Martinaud, Christophe Cap, Andrew P. Civadier, Corinne Clavier, Benoit Deshayes, Anne-Virginie Mendes, Anne-Christine Pouget, Thomas Demazeau, Nicolas Chueca, Marine Martelet, Francois-Regis Ausset, Sylvain TI The evolving role of lyophilized plasma in remote damage control resuscitation in the French Armed Forces Health Service SO TRANSFUSION LA English DT Article ID FREEZE-DRIED PLASMA AB Freeze-dried plasma was developed by the US Army for the resuscitation of combat casualties during World War II. The French Military Blood Institute began producing French lyophilized plasma (FLYP) in 1949, in accordance with French blood product guidelines. Since 2010, a photochemical pathogen inactivation process has been implemented to reduce the remaining transfusion-related infectious risk. All quality controls for this procedure verify that the hemostatic properties of FLYP are conserved. FLYP is compatible with all blood types, can be stored at room temperature for 2 years, and its reconstitution requires less than 6 minutes. As a result, FLYP allows quick delivery of all the coagulation proteins and the application of a 1:1 ratio of FLYP and red blood cells in the context of a massive transfusion. Hemovigilance data collected in France since 1994 have included FLYP. Results indicate no reporting of infection related to the use of FLYP. Clinical monitoring with a focus on hemostasis was implemented in 2002 and expanded in 2010. The data, obtained from overseas operations, confirmed the indications, the safety and the clinical efficacy of FLYP. Further research is needed to determine specific indications for FLYP in the therapeutic management of civilian patients with severe hemorrhage. C1 [Sailliol, Anne] CTSA, F-92140 Clamart, France. Federat Biol Clin, Clamart, France. HIA Percy, Dept Anesthesie & Reanimat, Clamart, France. USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. RP Sailliol, A (reprint author), CTSA, 1 Rue Raoul Batany, F-92140 Clamart, France. EM anne.sailliol@wanadoo.fr OI Ausset, Sylvain/0000-0001-8345-1058 NR 12 TC 31 Z9 32 U1 0 U2 12 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0041-1132 J9 TRANSFUSION JI Transfusion PD JAN PY 2013 VL 53 SU 1 SI SI BP 65S EP 71S DI 10.1111/trf.12038 PG 7 WC Hematology SC Hematology GA 071SR UT WOS:000313615000011 PM 23301975 ER PT J AU Wataha, K Menge, T Deng, X Shah, A Bode, A Holcomb, JB Potter, D Kozar, R Spinella, PC Pati, S AF Wataha, K. Menge, T. Deng, X. Shah, A. Bode, A. Holcomb, J. B. Potter, D. Kozar, R. Spinella, P. C. Pati, S. TI Spray-dried plasma and fresh frozen plasma modulate permeability and inflammation in vitro in vascular endothelial cells SO TRANSFUSION LA English DT Article ID RED-BLOOD-CELL; MASSIVE TRANSFUSION; FLUID RESUSCITATION; HEMORRHAGIC-SHOCK; GENE-TRANSCRIPTION; LYOPHILIZED PLASMA; TRAUMATIC INJURY; MORTALITY; HETASTARCH; SURVIVAL AB Background After major traumatic injury, patients often require multiple transfusions of fresh frozen plasma (FFP) to correct coagulopathy and to reduce bleeding. A spray-dried plasma (SDP) product has several logistical benefits over FFP use in trauma patients with coagulopathy. These benefits include ease of transport, stability at room temperature, and rapid reconstitution for infusion. Our past work suggests that FFP promotes endothelial stability by inhibiting endothelial permeability. Study Design and Methods The main goal of this project is to determine if solvent-detergent-treated SDP is equivalent to FFP in inhibiting vascular endothelial cell (EC) permeability and inflammation in vitro. Furthermore, this study aimed to determine if solvent-detergent treatment and spray drying of plasma alters the protective effects of FFP on EC function. The five groups tested in our studies are the following: 1) fresh frozen-thawed plasma (FFP); 2) solvent-detergent-treated FFP; 3) solvent-detergent-treated SDP; 4) lactated Ringer's solution; and 5) Hextend. Results This study demonstrates that in vitro SDP and FFP equivalently inhibit vascular EC permeability, EC adherens junction breakdown, and endothelial white blood cell binding, an effect that is independent of changes in Vascular Cell Adhesion Molecule 1, Intracellular Adhesion Molecule 1, or E-selectin expression on ECs. Solvent-detergent treatment of FFP does not alter the protective effects of FFP on endothelial cell function in vitro. Conclusion These data suggest the equivalence of FFP and SDP on modulation of endothelial function and inflammation in vitro. C1 [Pati, S.] Blood Syst Res Inst, San Francisco, CA 94118 USA. Univ Calif San Francisco, Dept Lab Med, San Francisco, CA 94143 USA. Entegrion Inc, Res Triangle Pk, NC USA. UTHSC, Dept Surg, Houston, TX USA. UTHSC, Ctr Translat Injury Res, Houston, TX USA. Washington Univ, Dept Pediat, Div Crit Care, St Louis, MO 63130 USA. USA, Inst Surg Res, San Antonio, TX USA. RP Pati, S (reprint author), Blood Syst Res Inst, 270 Masonic Ave, San Francisco, CA 94118 USA. EM spati@bloodsystems.org FU Entegrion; Office of Naval Research [N00014-10-C-0333] FX This study was supported in part by research funding from Entegrion to SP. Entegrion is a recipient of a grant from the Office of Naval Research under Contract No. N00014-10-C-0333 that supports this study. NR 32 TC 19 Z9 19 U1 0 U2 0 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0041-1132 J9 TRANSFUSION JI Transfusion PD JAN PY 2013 VL 53 SU 1 SI SI BP 80S EP 90S DI 10.1111/trf.12040 PG 11 WC Hematology SC Hematology GA 071SR UT WOS:000313615000013 PM 23301978 ER PT J AU Rappold, JF Pusateri, AE AF Rappold, Joseph F. Pusateri, Anthony E. TI Tranexamic acid in remote damage control resuscitation SO TRANSFUSION LA English DT Article ID CONTROLLED-TRIAL; CARDIAC-SURGERY; TRAUMA PATIENTS; TRANSFUSION; APROTININ; HEMORRHAGE; SEIZURES; CRASH-2; SAFETY AB With the advent of remote damage control resuscitation and far-forward surgery, a renewed emphasis has been placed on examining a variety of pharmacologic adjuncts to controlling blood loss before definitive operative intervention. In this paper, the authors review the current state of the art for tranexamic acid (TXA) and its potential benefits to those patients who are in need of a massive transfusion. Specifically addressed are its biologic and pharmacologic properties, as well the results of a number of recent studies. The 2010 CRASH-2 trial randomized in excess of 20,000 patients and demonstrated a reduction in all-cause mortality from 16.0 to 14.5% and death due to bleeding from 5.7 to 4.9%. The 2012 Military Application of Tranexamic Acid in Trauma Emergency Resuscitation study provided a retrospective analysis of 896 wounded cared for at a military hospital in Afghanistan. This study demonstrated a 23.9%-17.4% reduction in all-cause mortality. Finally, they discuss the potential complications associated with TXA use as well as areas of future research, which are needed to solidify our knowledge of TXA and its potential beneficial effects on controlling bleeding. C1 [Rappold, Joseph F.] Temple Univ, Sch Med, Dept Surg, Div Trauma & Crit Care, Philadelphia, PA 19140 USA. USA, Med Res & Mat Command, Dept Def Hemorrhage, Ft Detrick, MD USA. USA, Med Res & Mat Command, Resuscitat Res & Dev Program, Combat Casualty Care Res Program, Ft Detrick, MD USA. RP Rappold, JF (reprint author), Temple Univ, Sch Med, Dept Surg, Div Trauma & Crit Care, Philadelphia, PA 19140 USA. EM joseph.rappold@tuhs.temple.edu NR 21 TC 7 Z9 7 U1 0 U2 8 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0041-1132 J9 TRANSFUSION JI Transfusion PD JAN PY 2013 VL 53 SU 1 SI SI BP 96S EP 99S DI 10.1111/trf.12042 PG 4 WC Hematology SC Hematology GA 071SR UT WOS:000313615000015 PM 23301980 ER PT J AU Nessen, SC Eastridge, BJ Cronk, D Craig, RM Berseus, O Ellison, R Remick, K Seery, J Shah, A Spinella, PC AF Nessen, Shawn C. Eastridge, Brian J. Cronk, Daniel Craig, Robert M. Berseus, Olle Ellison, Richard Remick, Kyle Seery, Jason Shah, Avani Spinella, Philip C. TI Fresh whole blood use by forward surgical teams in Afghanistan is associated with improved survival compared to component therapy without platelets SO TRANSFUSION LA English DT Article ID DAMAGE CONTROL RESUSCITATION; ACUTE TRAUMATIC COAGULOPATHY; MASSIVE TRANSFUSION; COMBAT; OPERATIONS; BATTLEFIELD; EVOLUTION; INJURIES; PRODUCTS; OUTCOMES AB Background In Afghanistan, a substantial portion of resuscitative combat surgery is performed by US Army forward surgical teams (FSTs). Red blood cells (RBCs) and fresh frozen plasma (FFP) are available at these facilities, but platelets are not. FST personnel frequently encounter high-acuity patient scenarios without the ability to transfuse platelets. An analysis of the use of fresh whole blood (FWB) at FSTs therefore allows for an evaluation of outcomes associated with this practice. Study Design and Methods A retrospective analysis was performed in prospectively collected data from all transfused patients at six FSTs from December 2005 to December 2010. Univariate analysis was performed, followed by two separate propensity score analyses. In-hospital mortality was predicted with the use of a conditional logistic regression model that incorporated these propensity scores. Subset analysis included evaluation of patients who received uncrossmatched Type O FWB compared with those who received type-specific FWB. Results A total of 488 patients received a blood transfusion. There were no significant differences in age, sex, or Glasgow Coma Scale in those who received or did not receive FWB. Injury Severity Scores were higher in patients transfused FWB. In our adjusted analyses, patients who received RBCs and FFP with FWB had improved survival compared with those who received RBCs and FFP without FWB. Of 94 FWB recipients, 46 FWB recipients (49%) were given uncrossmatched Type O FWB, while 48 recipients (51%) received type-specific FWB. There was no significant difference in mortality between patients that received uncrossmatched Type O and type-specific FWB. Conclusions The use of FWB in austere combat environments appears to be safe and is independently associated with improved survival to discharge when compared with resuscitation with RBCs and FFP alone. Mortality was similar for patients transfused uncrossmatched Type O compared with ABO type-specific FWB in an austere setting. C1 212th Combat Support Hosp, Miseau, Germany. USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. Methodist Hlth Syst, Omaha, NE USA. Walter Reed Natl Mil Med Ctr, Bethesda, MD USA. Orebro Univ Hosp, Dept Transfus Med, Orebro, Sweden. Womack Army Med Ctr, Ft Bragg, NC USA. Hosp Univ Penn, Philadelphia, PA 19104 USA. Blood Syst Res Inst, San Francisco, CA USA. Washington Univ, Dept Pediat, St Louis, MO 63130 USA. RP Nessen, SC (reprint author), CMR 403,Box 4496, APO, AE 09059 USA. EM snessen74@gmail.com NR 38 TC 34 Z9 35 U1 1 U2 7 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0041-1132 J9 TRANSFUSION JI Transfusion PD JAN PY 2013 VL 53 SU 1 SI SI BP 107S EP 113S DI 10.1111/trf.12044 PG 7 WC Hematology SC Hematology GA 071SR UT WOS:000313615000017 PM 23301962 ER PT J AU Strandenes, G Cap, AP Cacic, D Lunde, THF Eliassen, HS Hervig, T Spinella, PC AF Strandenes, Geir Cap, Andrew P. Cacic, Daniel Lunde, Turid Helen Felli Eliassen, Hakon Skogrand Hervig, Tor Spinella, Philip C. TI Blood Far Forward-a whole blood research and training program for austere environments SO TRANSFUSION LA English DT Article ID FRESH-FROZEN PLASMA; FLUID RESUSCITATION; HEMORRHAGIC-SHOCK; CARDIAC-SURGERY; TRAUMA PATIENTS; STORAGE; REDUCTION; PLATELETS; COAGULOPATHY; TRANSFUSION AB The Blood Far Forward (BFF) research program was established to conduct blood product efficacy and safety studies, donor performance studies, and research on optimal training methods to improve the safety of blood collection and transfusion performed by Norwegian Naval Special Operation Commando soldiers. The use of intravenous fluids for volume replacement during hemorrhagic shock is controversial, but it is currently the standard of care. In the far-forward environment, large volume resuscitation for massive bleeding is a great challenge. Crystalloid and colloid solutions add weight and bulk to the medic's kit, require temperature sensitive storage, and should be warmed before infusion to prevent hypothermia. Excessive use of these solutions causes a dilutional coagulopathy, acidosis, and potentially increased inflammatory injury compared with blood products. Type-specific whole blood from an uninjured combat companion on the other hand is almost always available. It is warm, replaces intravascular volume, and provides oxygen delivery and hemostatic capacity to prevent or treat shock and coagulopathy. Whole blood may be ideal for the resuscitation of combat casualties with hemorrhagic shock. BFF program pilot studies on use of platelet-sparing leukoreduction filters, whole blood transport tolerance, donor performance, and autologous reinfusion of 24-hour ambient temperature stored whole blood have been performed and suggest the feasibility of expanding whole blood use in resuscitation. If successful, the BFF program will change tactics, techniques, and procedures with a new lifesaving capability. C1 [Strandenes, Geir] Norwegian Naval Special Operat Commando, N-5886 Bergen, Norway. Haukeland Hosp, Dept Immunol & Transfus Med, N-5021 Bergen, Norway. Univ Bergen, Gade Inst, Bergen, Norway. Washington Univ, Div Pediat Crit Care Med, St Louis, MO USA. USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. RP Strandenes, G (reprint author), Norwegian Naval Special Operat Commando, Postboks 1 Haakonsvern, N-5886 Bergen, Norway. EM geir@docfish.no NR 42 TC 11 Z9 11 U1 1 U2 4 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0041-1132 J9 TRANSFUSION JI Transfusion PD JAN PY 2013 VL 53 SU 1 SI SI BP 124S EP 130S DI 10.1111/trf.12046 PG 7 WC Hematology SC Hematology GA 071SR UT WOS:000313615000019 PM 23301964 ER PT J AU Pidcoke, HF McFaul, SJ Ramasubramanian, AK Parida, BK Mora, AG Fedyk, CG Valdez-Delgado, KK Montgomery, RK Reddoch, KM Rodriguez, AC Aden, JK Jones, JA Bryant, RS Scherer, MR Reddy, HL Goodrich, RP Cap, AP AF Pidcoke, Heather F. McFaul, Steve J. Ramasubramanian, Anand K. Parida, Bijaya K. Mora, Alex G. Fedyk, Chriselda G. Valdez-Delgado, Krystal K. Montgomery, Robbie K. Reddoch, Kristin M. Rodriguez, Armando C. Aden, James K. Jones, John A. Bryant, Ron S. Scherer, Michael R. Reddy, Heather L. Goodrich, Raymond P. Cap, Andrew P. TI Primary hemostatic capacity of whole blood: a comprehensive analysis of pathogen reduction and refrigeration effects over time SO TRANSFUSION LA English DT Article ID IMPROVED SURVIVAL; TRAUMA PATIENTS; APHERESIS PLATELETS; MASSIVE TRANSFUSION; ULTRAVIOLET-LIGHT; HEMORRHAGIC-SHOCK; PLASMA; COMBAT; RIBOFLAVIN; CLEARANCE AB Background Whole blood (WB) has been used in combat since World War I as it is readily available and replaces every element of shed blood. Component therapy has become standard; however, recent military successes with WB resuscitation have revived the debate regarding wider WB use. Characterization of optimal WB storage is needed. We hypothesized that refrigeration preserves WB function and that a pathogen reduction technology (PRT) based on riboflavin and ultraviolet light has no deleterious effect over 21 days of storage. Study Design and Methods WB units were stored for 21 days either at 4 degrees C or 22 degrees C. Half of each temperature group underwent PRT, yielding four final treatment groups (n?=?8 each): CON 4 (WB at 4 degrees C); CON 22 (WB at 22 degrees C); PRT 4 (PRT WB at 4 degrees C); and PRT 22 (PRT WB at 22 degrees C). Testing was at baseline, Days 1-7, 10, 14, and 21. Assays included coagulation factors; platelet activation, aggregation, and adhesion; and thromboelastography (TEG). Results Prothrombin time (PT) and partial thromboplastin time increased over time; refrigeration attenuated the effects on PT (p?=?0.009). Aggregation decreased over time (p?=?0.001); losses were attenuated by refrigeration (p?=?0.001). Refrigeration preserved TEG parameters (p?=?0.001) and PRT 4 samples remained within normal limits throughout the study. Refrigeration in combination with PRT inhibited fibrinolysis (p?=?0.001) and microparticle formation (p?=?0.031). Cold storage increased shear-induced platelet aggregation and ristocetin-induced platelet agglutination (p?=?0.032), as well as GPIb-expressing platelets (p?=?0.009). Conclusion The in vitro hemostatic function of WB is largely unaffected by PRT treatment and better preserved by cold storage over 21 days. Refrigerated PRT WB may be suitable for trauma resuscitation. Clinical studies are warranted. C1 [Cap, Andrew P.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. Univ Texas San Antonio, Dept Biomed Engn, San Antonio, TX USA. Terumo BCT Biotechnol LLC, Lakewood, CO USA. RP Cap, AP (reprint author), USA, Inst Surg Res, 3400 Rawley E Chambers Ave, Ft Sam Houston, TX 78234 USA. EM andre.p.cap@us.army.mil FU MRMC, Terumo BCT Biotechnologies FX Supported by: the MRMC, Terumo BCT Biotechnologies. NR 53 TC 41 Z9 41 U1 1 U2 17 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0041-1132 J9 TRANSFUSION JI Transfusion PD JAN PY 2013 VL 53 SU 1 SI SI BP 137S EP 149S DI 10.1111/trf.12048 PG 13 WC Hematology SC Hematology GA 071SR UT WOS:000313615000021 PM 23301966 ER PT J AU Zhong, Y Saengdeejing, A Kecskes, L Klotz, B Liu, ZK AF Zhong, Yu Saengdeejing, Arkapol Kecskes, Laszlo Klotz, Bradley Liu, Zi-Kui TI Experimental and computational studies of the Cu-Hf binary system SO ACTA MATERIALIA LA English DT Article DE First-principles calculations; Phase equilibria; Bulk amorphous alloy ID AUGMENTED-WAVE METHOD; COPPER-HAFNIUM; INTERMEDIATE PHASES; ALLOYS; ZIRCONIUM; PSEUDOPOTENTIALS; TITANIUM; DIAGRAM; METALS AB The thermodynamic properties and phase equilibria of the Cu-Hf binary system with five intermetallic compounds were studied by experiments, first-principles calculations and CALPHAD modeling. The experimental investigations included differential thermal analysis, scanning electron microscopy, energy dispersive X-ray microanalysis and micro-X-ray diffraction focusing on the 30-60 at.% Hf composition range to determine the invariant reaction temperatures. Cu10Hf7 was confirmed to melt incongruently. The enthalpies of formation of all five binary Cu-Hf compounds were predicted through first-principles calculations. The atomic configuration of one of the compounds, Cu51Hf14, was postulated through systematic first-principles calculations with 65 atoms instead of 68 atoms, denoted by hp68 in the literature. The thermodynamic description of the Cu-Hf binary system was then obtained from the new experimental data and first-principles calculations. (c) 2012 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved. C1 [Zhong, Yu; Saengdeejing, Arkapol; Liu, Zi-Kui] Penn State Univ, Dept Mat Sci & Engn, University Pk, PA 16802 USA. [Kecskes, Laszlo] USA, Res Lab, Weap & Mat Res Directorate, RDRL WMM F, Aberdeen Proving Ground, MD 21005 USA. [Klotz, Bradley] Dynam Sci Inc, Aberdeen Proving Ground, MD 21005 USA. RP Zhong, Y (reprint author), Penn State Univ, Dept Mat Sci & Engn, University Pk, PA 16802 USA. EM zhongpsu@gmail.com RI Zhong, Yu/I-1603-2013; Kecskes, Laszlo/F-6880-2014; Liu, Zi-Kui/A-8196-2009 OI Zhong, Yu/0000-0002-2363-7093; Kecskes, Laszlo/0000-0002-1342-3729; Liu, Zi-Kui/0000-0003-3346-3696 FU US Army Research Laboratory (ARL) [W911NF-09-2-0045]; National Science Foundation [OCI-0821527] FX This work was funded by the US Army Research Laboratory (ARL) through the agreement W911NF-09-2-0045. First-principles calculations were carried out on the Cyber-STAR cluster at the Pennsylvania State University, supported in part by the National Science Foundation through grant OCI-0821527.We would like to thank Mark Angelone at the Pennsylvania State University for help on the micro-XRD analysis. NR 34 TC 0 Z9 0 U1 0 U2 29 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 1359-6454 J9 ACTA MATER JI Acta Mater. PD JAN PY 2013 VL 61 IS 2 BP 660 EP 669 DI 10.1016/j.actamat.2012.10.014 PG 10 WC Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering SC Materials Science; Metallurgy & Metallurgical Engineering GA 068VI UT WOS:000313393900022 ER PT J AU Cheuvront, SN Kenefick, RW Sollanek, KJ Ely, BR Sawka, MN AF Cheuvront, Samuel N. Kenefick, Robert W. Sollanek, Kurt J. Ely, Brett R. Sawka, Michael N. TI Water-deficit equation: systematic analysis and improvement SO AMERICAN JOURNAL OF CLINICAL NUTRITION LA English DT Article ID OLDER-ADULTS; BODY-WATER; SERUM OSMOLARITY; DEHYDRATION; EXERCISE; SODIUM; PLASMA; FLUID; MASS; HYPERNATREMIA AB Background: The water-deficit equation {WD1 = 0.6 x B-m X [1 - (140 divided by Na+)]; B-m denotes body mass} is used in medicine and nutrition to estimate the volume (L) of water required to correct dehydration during the initial stages of fluid-replacement therapy. Several equation assumptions may limit its accuracy, but none have been systematically tested. Objectives: We quantified the potential error in WD1 for the estimation of free water (FW) and total body water (TBW) losses and systematically evaluated its assumptions. Design: Thirty-six euhydrated volunteers were dehydrated (2.2-5.8% B-m) via thermoregulatory sweating. Assumptions within WD1 were tested by substituting measured euhydrated values for assumed or unknown values. These included the known (premorbid) Bm (WD2), a proposed correction for unknown B-m (WD3), the TBW estimated from body composition (WD4), the actual plasma sodium (WD5), the substitution of plasma osmolality (Posm) for sodium (WD6), and actual Posm (WD7). Results: Dehydration reduced TBW by 3.49 +/- 0.91 L, 57% of which (2.02 +/- 0.96 L) was FW loss, and increased plasma sodium from 139 (range: 135-143 mmol/L) to 143 (range: 141-148 mmol/L) mmol/L. Calculations for WD1 through WD7 all underestimated TBW loss by 1.5-2.5 L (P < 0.05). WD1 through WD3 underestimated FW by 0.5 L to 1.0 L (P < 0.05), but WD6 and WD7 estimated FW loss to within 0.06-0.16 L (P > 0.05). Conclusions: WD1 grossly underestimates TBW and FW losses. Corrections for unknowns and assumptions (WD2 through WD5) improved estimates little. The use of WD6 = 0.6 X B-m X [1 - (290 divided by Posm)] accurately estimates FW but still underestimates TBW losses by >40%. Am J Clin Nutr 2013;97:79-85. C1 [Cheuvront, Samuel N.] USA, Thermal & Mt Med Div, Environm Med Res Inst, Natick, MA 01760 USA. RP Cheuvront, SN (reprint author), USA, Thermal & Mt Med Div, Environm Med Res Inst, Kansas St,Bldg 42, Natick, MA 01760 USA. EM samuel.n.cheuvront@us.army.mil FU United States Amy Medical Research and Materiel Command FX Supported by the United States Amy Medical Research and Materiel Command. NR 44 TC 9 Z9 9 U1 2 U2 11 PU AMER SOC NUTRITION-ASN PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 USA SN 0002-9165 J9 AM J CLIN NUTR JI Am. J. Clin. Nutr. PD JAN PY 2013 VL 97 IS 1 BP 79 EP 85 DI 10.3945/ajcn.112.046839 PG 7 WC Nutrition & Dietetics SC Nutrition & Dietetics GA 065GD UT WOS:000313135600012 PM 23235197 ER PT J AU Kuhn, JH Radoshitzky, SR Bavari, S Jahrling, PB AF Kuhn, Jens H. Radoshitzky, Sheli R. Bavari, Sina Jahrling, Peter B. TI The International Code of Virus Classification and Nomenclature (ICVCN): proposal to delete Rule 3.41 SO ARCHIVES OF VIROLOGY LA English DT Article AB It is proposed to delete Rule 3.41 of the International Code of Virus Classification and Nomenclature, which requires the name of a virus taxon to precede the term for the taxonomic unit. C1 [Kuhn, Jens H.; Jahrling, Peter B.] NIAID, Integrated Res Facil Ft Detrick IRF Frederick, Div Clin Res DCR, NIH, Frederick, MD USA. [Radoshitzky, Sheli R.; Bavari, Sina] USA, Med Res Inst Infect Dis, Frederick, MD USA. RP Kuhn, JH (reprint author), NIAID, Integrated Res Facil Ft Detrick IRF Frederick, Div Clin Res DCR, NIH, Frederick, MD USA. EM kuhnjens@mail.nih.gov RI Kuhn, Jens H./B-7615-2011 OI Kuhn, Jens H./0000-0002-7800-6045 FU Joint Science and Technology Office for Chem Bio Defense [TMTI0048_09_RD_T]; NIAID [HHSN272200200016I] FX The content of this publication does not necessarily reflect the views or policies of the US Department of the Army, the US Department of Defense or the US Department of Health and Human Services or of the institutions and companies affiliated with the authors. This work was funded by the Joint Science and Technology Office for Chem Bio Defense (proposal #TMTI0048_09_RD_T) to SB and SRR. JHK performed this work as an employee of Tunnell Consulting, Inc., a subcontractor to Battelle Memorial Institute, and FKM as an employee of Battelle Memorial Institute, under its prime contract with NIAID, under Contract No. HHSN272200200016I. NR 2 TC 4 Z9 4 U1 0 U2 5 PU SPRINGER WIEN PI WIEN PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 WIEN, AUSTRIA SN 0304-8608 J9 ARCH VIROL JI Arch. Virol. PD JAN PY 2013 VL 158 IS 1 BP 297 EP 299 DI 10.1007/s00705-012-1453-1 PG 3 WC Virology SC Virology GA 067KY UT WOS:000313294200041 PM 22932924 ER PT J AU Kuhn, JH Bao, YM Bavari, S Becker, S Bradfute, S Brister, JR Bukreyev, AA Chandran, K Davey, RA Dolnik, O Dye, JM Enterlein, S Hensley, LE Honko, AN Jahrling, PB Johnson, KM Kobinger, G Leroy, EM Lever, MS Muhlberger, E Netesov, SV Olinger, GG Palacios, G Patterson, JL Paweska, JT Pitt, L Radoshitzky, SR Saphire, EO Smither, SJ Swanepoel, R Towner, JS van der Groen, G Volchkov, VE Wahl-Jensen, V Warren, TK Weidmann, M Nichol, ST AF Kuhn, Jens H. Bao, Yiming Bavari, Sina Becker, Stephan Bradfute, Steven Brister, J. Rodney Bukreyev, Alexander A. Chandran, Kartik Davey, Robert A. Dolnik, Olga Dye, John M. Enterlein, Sven Hensley, Lisa E. Honko, Anna N. Jahrling, Peter B. Johnson, Karl M. Kobinger, Gary Leroy, Eric M. Lever, Mark S. Muehlberger, Elke Netesov, Sergey V. Olinger, Gene G. Palacios, Gustavo Patterson, Jean L. Paweska, Janusz T. Pitt, Louise Radoshitzky, Sheli R. Saphire, Erica Ollmann Smither, Sophie J. Swanepoel, Robert Towner, Jonathan S. van der Groen, Guido Volchkov, Viktor E. Wahl-Jensen, Victoria Warren, Travis K. Weidmann, Manfred Nichol, Stuart T. TI Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae SO ARCHIVES OF VIROLOGY LA English DT Article ID TAXONOMY; NAMES; IDENTIFICATION; VIROLOGISTS; EBOLAVIRUS; PROPOSAL AB The task of international expert groups is to recommend the classification and naming of viruses. The International Committee on Taxonomy of Viruses Filoviridae Study Group and other experts have recently established an almost consistent classification and nomenclature for filoviruses. Here, further guidelines are suggested to include their natural genetic variants. First, this term is defined. Second, a template for full-length virus names (such as "Ebola virus H.sapiens-tc/COD/1995/Kikwit-9510621") is proposed. These names contain information on the identity of the virus (e.g., Ebola virus), isolation host (e.g., members of the species Homo sapiens), sampling location (e.g., Democratic Republic of the Congo (COD)), sampling year, genetic variant (e.g., Kikwit), and isolate (e.g., 9510621). Suffixes are proposed for individual names that clarify whether a given genetic variant has been characterized based on passage zero material (-wt), has been passaged in tissue/cell culture (-tc), is known from consensus sequence fragments only (-frag), or does (most likely) not exist anymore (-hist). We suggest that these comprehensive names are to be used specifically in the methods section of publications. Suitable abbreviations, also proposed here, could then be used throughout the text, while the full names could be used again in phylograms, tables, or figures if the contained information aids the interpretation of presented data. The proposed system is very similar to the well-known influenzavirus nomenclature and the nomenclature recently proposed for rotaviruses. If applied consistently, it would considerably simplify retrieval of sequence data from electronic databases and be a first important step toward a viral genome annotation standard as sought by the National Center for Biotechnology Information (NCBI). Furthermore, adoption of this nomenclature would increase the general understanding of filovirus-related publications and presentations and improve figures such as phylograms, alignments, and diagrams. Most importantly, it would counter the increasing confusion in genetic variant naming due to the identification of ever more sequences through technological breakthroughs in high-throughput sequencing and environmental sampling. C1 [Kuhn, Jens H.; Jahrling, Peter B.; Wahl-Jensen, Victoria] NIAID, Integrated Res Facil Ft Detrick IRF Frederick, Div Clin Res DCR, NIH, Frederick, MD USA. [Bao, Yiming; Brister, J. Rodney] Natl Lib Med, Informat Engn Branch, Natl Ctr Biotechnol Informat, NIH, Bethesda, MD USA. [Bavari, Sina; Dye, John M.; Honko, Anna N.; Olinger, Gene G.; Palacios, Gustavo; Pitt, Louise; Radoshitzky, Sheli R.; Warren, Travis K.] USA, Med Res Inst Infect Dis, Frederick, MD USA. [Becker, Stephan; Dolnik, Olga] Univ Marburg, Inst Virol, D-35032 Marburg, Germany. [Bradfute, Steven] Univ New Mexico, Albuquerque, NM 87131 USA. [Bukreyev, Alexander A.] Univ Texas Med Branch, Galveston Natl Lab, Galveston, TX 77555 USA. [Chandran, Kartik] Albert Einstein Coll Med, Dept Microbiol & Immunol, Bronx, NY 10467 USA. [Davey, Robert A.; Patterson, Jean L.] Texas Biomed Res Inst, Dept Virol & Immunol, San Antonio, TX USA. [Enterlein, Sven] Integrated BioTherapeut Inc, Gaithersburg, MD USA. [Hensley, Lisa E.] Fed Drug Adm, Med Countermeasure Initiat, Silver Spring, MD USA. [Kobinger, Gary] Publ Hlth Agcy Canada, Natl Microbiol Lab, Special Pathogens Program, Winnipeg, MB, Canada. [Leroy, Eric M.] Ctr Int Rech Med Franceville, Franceville, Gabon. [Lever, Mark S.; Smither, Sophie J.] Dstl, Dept Biomed Sci, Porton Down, Salisbury, Wilts, England. [Muehlberger, Elke] Univ Sch Med, Natl Emerging Infect Dis Lab, Boston, MA USA. [Netesov, Sergey V.] Novosibirsk State Univ, Novosibirsk 630090, Novosibirsk Obl, Russia. [Paweska, Janusz T.] Natl Hlth Lab Serv, Natl Inst Communicable Dis, Ctr Emerging & Zoonot Dis, Johannesburg, Gauteng, South Africa. [Saphire, Erica Ollmann] Scripps Res Inst, Dept Immunol & Microbial Sci, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA. [Swanepoel, Robert] Univ Pretoria, Zoonoses Res Unit, ZA-0002 Pretoria, South Africa. [Towner, Jonathan S.; Nichol, Stuart T.] Ctr Dis Control & Prevent, Viral Special Pathogens Branch, Div High Consequence Pathogens Pathol, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA. [van der Groen, Guido] Prins Leopold Inst Trop Geneeskunde, Antwerp, Belgium. [Volchkov, Viktor E.] Univ Lyon, Lab Filovirus, Ecole Normale Super Lyon, INSERM,U758,UCB Lyon 1, Lyon, France. [Weidmann, Manfred] Univ Med Gottingen, Abt Virol, Gottingen, Germany. RP Kuhn, JH (reprint author), NIAID, Integrated Res Facil Ft Detrick IRF Frederick, Div Clin Res DCR, NIH, B-8200 Res Plaza, Frederick, MD USA. EM kuhnjens@mail.nih.gov; stn1@cdc.gov RI LEROY, Eric/I-4347-2016; Netesov, Sergey/A-3751-2013; Volchkov, Viktor/M-7846-2014; Kuhn, Jens H./B-7615-2011; Becker, Stephan/A-1065-2010; Palacios, Gustavo/I-7773-2015; Weidmann, Manfred/G-1817-2015; OI Honko, Anna/0000-0001-9165-148X; LEROY, Eric/0000-0003-0022-0890; Muhlberger, Elke/0000-0003-3547-9376; Netesov, Sergey/0000-0002-7786-2464; Volchkov, Viktor/0000-0001-7896-8706; Kuhn, Jens H./0000-0002-7800-6045; Becker, Stephan/0000-0002-2794-5659; Palacios, Gustavo/0000-0001-5062-1938; Weidmann, Manfred/0000-0002-7063-7491; Olinger, Gene/0000-0001-7338-0292 FU Joint Science and Technology Office for Chem Bio Defense [TMTI0048_09_RD_T]; NIAID [HHSN272200200016I]; NIH, National Library of Medicine FX The content of this publication does not necessarily reflect the views or policies of the US Department of the Army, the US Department of Defense or the US Department of Health and Human Services or of the institutions and companies affiliated with the authors. This work was funded in part by the Joint Science and Technology Office for Chem Bio Defense (proposal #TMTI0048_09_RD_T to SB). JHK and VWJ performed this work as employees of Tunnell Consulting, Inc., a subcontractor to Battelle Memorial Institute under its prime contract with NIAID, under Contract No. HHSN272200200016I. This research was also supported in part by the Intramural Research Program of the NIH, National Library of Medicine (YB and JRB). NR 36 TC 49 Z9 50 U1 2 U2 32 PU SPRINGER WIEN PI WIEN PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 WIEN, AUSTRIA SN 0304-8608 EI 1432-8798 J9 ARCH VIROL JI Arch. Virol. PD JAN PY 2013 VL 158 IS 1 BP 301 EP 311 DI 10.1007/s00705-012-1454-0 PG 11 WC Virology SC Virology GA 067KY UT WOS:000313294200042 PM 23001720 ER PT J AU Cervenka, MC Franaszczuk, PJ Crone, NE Hong, B Caffo, BS Bhatt, P Lenz, FA Boatman-Reich, D AF Cervenka, Mackenzie C. Franaszczuk, Piotr J. Crone, Nathan E. Hong, Bo Caffo, Brian S. Bhatt, Paras Lenz, Frederick A. Boatman-Reich, Dana TI Reliability of early cortical auditory gamma-band responses SO CLINICAL NEUROPHYSIOLOGY LA English DT Article DE Auditory cortex; Gamma-band; Reliability; Auditory processing; Variability ID TEST-RETEST RELIABILITY; HUMAN INTRACRANIAL RECORDINGS; SUPERIOR TEMPORAL GYRUS; EVENT-RELATED RESPONSES; HUMAN CORTEX; HUMAN EEG; INVOLUNTARY ATTENTION; MISMATCH NEGATIVITY; EVOKED-POTENTIALS; INTENSITY CHANGES AB Objective: To evaluate the test-retest reliability of event-related power changes in the 30-150 Hz gamma frequency range occurring in the first 150 ms after presentation of an auditory stimulus. Methods: Repeat intracranial electrocorticographic (ECoG) recordings were performed with 12 epilepsy patients, at >= 1 day intervals, using a passive odd-ball paradigm with steady-state tones. Time-frequency matching pursuit analysis was used to quantify changes in gamma-band power relative to pre-stimulus baseline. Test-retest reliability was estimated based on within-subject comparisons (paired t-test, McNemar's test) and correlations (Spearman rank correlations, intra-class correlations) across sessions, adjusting for within-session variability. Reliability estimates of gamma-band response robustness, spatial concordance, and reproducibility were compared with corresponding measurements from concurrent auditory evoked N1 responses. Results: All patients showed increases in gamma-band power, 50-120 ms post-stimulus onset, that were highly robust across recordings, comparable to the evoked N1 responses. Gamma-band responses occurred regardless of patients' performance on behavioral tests of auditory processing, medication changes, seizure focus, or duration of test-retest interval. Test-retest reproducibility was greatest for the timing of peak power changes in the high-gamma range (65-150 Hz). Reliability of low-gamma responses and evoked N1 responses improved at higher signal-to-noise levels. Conclusions: Early cortical auditory gamma-band responses are robust, spatially concordant, and reproducible over time. Significance: These test-retest ECoG results confirm the reliability of auditory gamma-band responses, supporting their utility as objective measures of cortical processing in clinical and research studies. (C) 2012 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved. C1 [Boatman-Reich, Dana] Johns Hopkins Sch Med, Dept Neurol, Epilepsy Div, Baltimore, MD 21287 USA. [Franaszczuk, Piotr J.] USA, Human Res & Engn Directorate, Res Lab, Aberdeen Proving Ground, MD USA. [Hong, Bo] Tsinghua Univ, Sch Med, Dept Biomed Engn, Beijing 100084, Peoples R China. [Caffo, Brian S.] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Biostat, Baltimore, MD USA. [Lenz, Frederick A.] Johns Hopkins Univ, Sch Med, Dept Neurosurg, Baltimore, MD 21205 USA. RP Boatman-Reich, D (reprint author), Johns Hopkins Sch Med, Dept Neurol, Epilepsy Div, 600 N Wolfe St,Meyer 2-147, Baltimore, MD 21287 USA. EM dboatma@jhmi.edu RI Franaszczuk, Piotr/B-6532-2008 OI Franaszczuk, Piotr/0000-0002-5166-4224 FU NIH [NIDCD DC005645, DC010028, NIBIB EB012547, NINDS NS40596, NS038493]; National Science Foundation of China [61071003] FX This study was supported by NIH grants NIDCD DC005645 and DC010028 (D. B. R.); NIBIB EB012547 (B. C.); NINDS NS40596 (N.E.C.) and NS038493 (F. A. L.); and by the National Science Foundation of China Project 61071003 (B. H.). Special thanks to Dr. Deepti Ramadoss and Juan Roberto Perilla for assistance with the manuscript and figures. NR 68 TC 7 Z9 8 U1 1 U2 17 PU ELSEVIER IRELAND LTD PI CLARE PA ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000, IRELAND SN 1388-2457 J9 CLIN NEUROPHYSIOL JI Clin. Neurophysiol. PD JAN PY 2013 VL 124 IS 1 BP 70 EP 82 DI 10.1016/j.clinph.2012.06.003 PG 13 WC Clinical Neurology; Neurosciences SC Neurosciences & Neurology GA 067KU UT WOS:000313293800011 PM 22771035 ER PT J AU Angelini, DJ Dorsey, RM Willis, KL Hong, C Moyer, RA Oyler, J Jensen, NS Salem, H AF Angelini, Daniel J. Dorsey, Russell M. Willis, Kristen L. Hong, Charles Moyer, Robert A. Oyler, Jonathan Jensen, Neil S. Salem, Harry TI Chemical warfare agent and biological toxin-induced pulmonary toxicity: could stem cells provide potential therapies? SO INHALATION TOXICOLOGY LA English DT Review DE Acute lung injury (ALI); acute respiratory distress syndrome (ARDS); biological toxin; chemical warfare agents (CWAs); respiratory toxicity; stem cells ID ACUTE LUNG INJURY; RESPIRATORY-DISTRESS-SYNDROME; ENDOTHELIAL PROGENITOR CELLS; STAPHYLOCOCCAL-ENTEROTOXIN-B; NECROSIS-FACTOR-ALPHA; MARROW STROMAL CELLS; BRONCHOALVEOLAR LAVAGE FLUID; ALVEOLAR EPITHELIAL-CELLS; BLOOD-BRAIN-BARRIER; MICROINSTILLATION INHALATION EXPOSURE AB Chemical warfare agents (CWAs) as well as biological toxins present a significant inhalation injury risk to both deployed warfighters and civilian targets of terrorist attacks. Inhalation of many CWAs and biological toxins can induce severe pulmonary toxicity leading to the development of acute lung injury (ALI) as well as acute respiratory distress syndrome (ARDS). The therapeutic options currently used to treat these conditions are very limited and mortality rates remain high. Recent evidence suggests that human stem cells may provide significant therapeutic options for ALI and ARDS in the near future. The threat posed by CWAs and biological toxins for both civilian populations and military personnel is growing, thus understanding the mechanisms of toxicity and potential therapies is critical. This review will outline the pulmonary toxic effects of some of the most common CWAs and biological toxins as well as the potential role of stem cells in treating these types of toxic lung injuries. C1 [Angelini, Daniel J.; Dorsey, Russell M.; Willis, Kristen L.; Salem, Harry] USA, Dev & Engn Command, Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD 21010 USA. [Angelini, Daniel J.; Willis, Kristen L.] CNR, Res Associates Program, Washington, DC 20418 USA. [Willis, Kristen L.; Hong, Charles; Moyer, Robert A.] Def Threat Reduct Agcy, Directorate Res & Dev J9, Chem & Biol Technol Dept, Ft Belvoir, VA USA. [Oyler, Jonathan] USA, Med Res Inst Chem Def, Med Command, Aberdeen Proving Ground, MD 21010 USA. [Jensen, Neil S.] Joint Program Execut Off, Aberdeen Proving Ground, MD USA. [Salem, Harry] Chem Secur Assessment Ctr, Dept Homeland Secur, Aberdeen Proving Ground, MD USA. RP Salem, H (reprint author), USA, Dev & Engn Command, Edgewood Chem Biol Ctr, 5183 Blackhawk Rd, Aberdeen Proving Ground, MD 21010 USA. EM harry.salem.civ@mail.mil FU Edgewood Chemical Biological Center; Department of Homeland Security; Defense Threat Reduction Agency FX The work in the corresponding author's laboratory is funded through the Edgewood Chemical Biological Center and the Department of Homeland Security. D.J.A. is a recipient of a National Research Council Senior Research Associateship. K. L. W. is the recipient of a National Research Council Research Associateship supported and funded through the Defense Threat Reduction Agency. The views expressed in this manuscript are those of the author(s) and do not reflect the official policy of the Department of the Army, Department of Defense, Department of Homeland Security, or the U. S. Government. NR 287 TC 4 Z9 5 U1 0 U2 77 PU INFORMA HEALTHCARE PI LONDON PA TELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLAND SN 0895-8378 EI 1091-7691 J9 INHAL TOXICOL JI Inhal. Toxicol. PD JAN PY 2013 VL 25 IS 1 BP 37 EP 62 DI 10.3109/08958378.2012.750406 PG 26 WC Toxicology SC Toxicology GA 067HV UT WOS:000313285800006 PM 23293972 ER PT J AU Natesan, S Zamora, DO Wrice, NL Baer, DG Christy, RJ AF Natesan, Shanmugasundaram Zamora, David O. Wrice, Nicole L. Baer, David G. Christy, Robert J. TI Bilayer Hydrogel With Autologous Stem Cells Derived From Debrided Human Burn Skin for Improved Skin Regeneration SO JOURNAL OF BURN CARE & RESEARCH LA English DT Article ID HUMAN ADIPOSE-TISSUE; OPERATION IRAQI FREEDOM; COMBAT BURNS; REPAIR; PARTICIPATION; BIOMATERIALS; SCAFFOLDS; MARKERS; FATE AB The objective of this study was to demonstrate that stem cells isolated from discarded skin obtained after debridement can be used with collagen and fibrin-based scaffolds to develop a tissue-engineered vascularized dermal equivalent. Discarded tissue samples were collected from severely burned patients undergoing wound debridement. Stem cells were isolated from the adipose tissue layer and their growth and immunophenotype characterized. To develop a skin equivalent, debrided skin adipose stem cells (dsASCs) were added to a collagen-polyethylene glycol (PEG) fibrin-based bilayer hydrogel and analyzed in vitro. The effect of the bilayered hydrogels on wound healing was demonstrated using an excision wound model in athymic rats. The dsASCs isolated from all samples were CD90, CD105, and stromal cell surface protein-1 positive, similar to adipose stem cells isolated from normal human lipoaspirates. Within the bilayer hydrogels, dsASCs proliferated and differentiated, maintained a spindle-shaped morphology in collagen, and developed a tubular microvascular network in the PEGylated fibrin. Rat excision wounds treated with bilayer hydrogels showed less wound contraction and exhibited better dermal matrix deposition and epithelial margin progression than controls. Stem cells can be isolated from the adipose layer of burned skin obtained during debridement. When dsASCs are incorporated within collagen-PEGylated fibrin bilayer hydrogels, they develop stromal and vascular phenotypes through matrix-directed differentiation without use of growth factors. Preliminary in vivo studies indicate that dsASC-bilayer hydrogels contribute significantly to wound healing and provide support for their use as a vascularized dermal substitute for skin regeneration to treat large surface area burns. (J Burn Care Res 2013;34:18-30) C1 [Natesan, Shanmugasundaram; Zamora, David O.; Wrice, Nicole L.; Baer, David G.; Christy, Robert J.] USA, Dept Extrem Trauma Res & Regenerat Med, Inst Surg Res, Ft Sam Houston, TX 78234 USA. RP Christy, RJ (reprint author), USA, Dept Extrem Trauma Res & Regenerat Med, Inst Surg Res, 3698 Chambers Pass,Bldg 3611 BHT1, Ft Sam Houston, TX 78234 USA. OI Zamora, David/0000-0002-7003-5933; Natesan, Shanmugasundaram/0000-0003-4213-3111 FU Pittsburgh Tissue Engineering Initiative (PTEI); Geneva Foundation; U.S. Army Medical Research and Materiel Command FX SN is supported by a fellowship from the Pittsburgh Tissue Engineering Initiative (PTEI). DOZ is supported by a grant awarded by the Geneva Foundation.; The opinions and assertions contained herein are the private views of the authors and are not to be construed as official or reflecting the views of the Department of Defense or Department of Army. The authors are employees of the U.S. Government, and this work was prepared as part of their official duties. This research was funded by the U.S. Army Medical Research and Materiel Command. NR 43 TC 10 Z9 11 U1 4 U2 34 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 1559-047X J9 J BURN CARE RES JI J. Burn Care Res. PD JAN-FEB PY 2013 VL 34 IS 1 BP 18 EP 30 DI 10.1097/BCR.0b013e3182642c0e PG 13 WC Emergency Medicine; Dermatology; Surgery SC Emergency Medicine; Dermatology; Surgery GA 068IH UT WOS:000313359400015 PM 23292571 ER PT J AU Mann-Salinas, EA Baun, MM Meininger, JC Murray, CK Aden, JK Wolf, SE Wade, CE AF Mann-Salinas, Elizabeth A. Baun, Mara M. Meininger, Janet C. Murray, Clinton K. Aden, James K. Wolf, Steven E. Wade, Charles E. TI Novel Predictors of Sepsis Outperform the American Burn Association Sepsis Criteria in the Burn Intensive Care Unit Patient SO JOURNAL OF BURN CARE & RESEARCH LA English DT Article ID DECISION-SUPPORT-SYSTEMS; ORGAN DYSFUNCTION; INSULIN-RESISTANCE; DEFINITIONS; INFECTION; MORTALITY; GLUCOSE; TRAUMA; IMPACT AB The purpose of this study was to determine whether systemic inflammatory response syndrome (SIRS) and American Burn Association (ABA) criteria predict sepsis in the burn patient and develop a model representing the best combination of novel clinical sepsis predictors. A retrospective, case-controlled, within-patient comparison of burn patients admitted to a single intensive care unit from January 2005 to September 2010 was made. Blood culture results were paired with documented sepsis: positive-sick, negative-sick (collectively defined as sick), and negative-not sick. Data for all predictors were collected for the 72 hours before blood culture. Variables were evaluated using regression and area under the curve (AUC) analyses. Fifty-nine subjects represented 177 culture periods. SIRS criteria were not discriminative: 98% of the subjects met criteria. ABA sepsis criteria were different on the day before (P = .004). The six best-fit variables identified for the model included heart rate > 130 beats per min, mean arterial pressure < 60 mm Hg, base deficit < -6 mEq/L, temperature < 36 degrees C, use of vasoactive medications, and glucose > 150 mg/dl. The model was significant in predicting positive-sick and sick, with an AUC of 0.775 (P < .001) and 0.714 (P < .001), respectively; comparatively, the ABA criteria AUC was 0.619 (P = .028) and 0.597 (P = .035), respectively. Usefulness of the ABA criteria to predict sepsis is limited to the day before blood culture is obtained. A significant contribution of this research is the identification of six novel sepsis predictors for the burn patient. (J Burn Care Res 2013;34:31-43) C1 [Mann-Salinas, Elizabeth A.; Baun, Mara M.; Meininger, Janet C.; Wade, Charles E.] Univ Texas Hlth Sci Ctr, Sch Nursing, Houston, TX USA. [Mann-Salinas, Elizabeth A.; Aden, James K.] USA, Army Burn Ctr, Inst Surg Res, San Antonio, TX USA. [Murray, Clinton K.] San Antonio Mil Med Ctr, Dept Infect Dis, San Antonio, TX USA. [Wolf, Steven E.] Univ Texas SW Med Ctr Dallas, Div Burns Trauma & Crit Care, Dept Surg, Dallas, TX 75390 USA. RP Mann-Salinas, EA (reprint author), USA, Inst Surg Res, 3650 Chambers Pass, Houston, TX 78234 USA. OI Wolf, Steven/0000-0003-2972-3440 FU TriService Nursing Research Program [HU0001-10-1-TS06] FX This study was funded by the TriService Nursing Research Program HU0001-10-1-TS06. NR 34 TC 6 Z9 8 U1 1 U2 11 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 1559-047X J9 J BURN CARE RES JI J. Burn Care Res. PD JAN-FEB PY 2013 VL 34 IS 1 BP 31 EP 43 DI 10.1097/BCR.0b013e31826450b5 PG 13 WC Emergency Medicine; Dermatology; Surgery SC Emergency Medicine; Dermatology; Surgery GA 068IH UT WOS:000313359400016 PM 23135212 ER PT J AU Burns, CJ Chung, KK Aden, JK Lundy, JB Nitzschke, SL Renz, EM Cancio, LC AF Burns, Christopher J. Chung, Kevin K. Aden, James K. Lundy, Jonathan B. Nitzschke, Stephanie L. Renz, Evan M. Cancio, Leopoldo C. TI High Risk But Not Always Lethal: The Effect of Cirrhosis on Thermally Injured Adults SO JOURNAL OF BURN CARE & RESEARCH LA English DT Article ID STAGE LIVER-DISEASE; ABDOMINAL OPERATIONS; NONHEPATIC SURGERY; MODEL; MORTALITY; SCORE AB The aim of this article was to determine the effect of cirrhosis on mortality in thermally injured adult patients. We conducted a retrospective review of patients admitted to our burn center during 2003 to 2010. Eight hundred eight patients were included in this study, of whom 24 had the diagnosis of cirrhosis established from electronic medical records and/or autopsy reports. The mortality rate for the cirrhotic patients was 50%, and for the noncirrhotic patients it was 14.8%. On logistic regression, age (odds ratio [OR], 1.08; confidence interval [CI], 1.06-1.10), TBSA (OR, 1.08; CI, 1.06-1.10), inhalation injury (OR, 3.17, CI, 1.61-6.25), and cirrhosis (OR, 8.78; CI, 2.97-25.98) had independent effects on mortality. Of the 24 cirrhotic patients in this study, the admission Model for End-Stage Liver Disease score for the patients who survived hospitalization was 12.1 +/- 4.0, and for the patients who died it was 13.8 +/- 6.0 (P = .4). When comparing patients with 10 to 50% TBSA burn, the mortality rate for cirrhotic patients was 83.3% (10/12), and for the noncirrhotic patients it was only 12.7% (50/394), P < .0001. Adults with cirrhosis are rarely able to survive burn injuries > 10% TBSA. Although we did not detect a significant association between admission Model for End-Stage Liver Disease score and death, the presence of cirrhosis is a high premorbid contributor and, therefore, new strategies are needed to improve outcomes. (J Burn Care Res 2013;34:115-119) C1 [Burns, Christopher J.; Chung, Kevin K.; Aden, James K.; Lundy, Jonathan B.; Nitzschke, Stephanie L.; Renz, Evan M.; Cancio, Leopoldo C.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Burns, Christopher J.] USN, Med Res Unit, Ft Sam Houston, TX USA. RP Chung, KK (reprint author), USA, Inst Surg Res, 3698 Chambers Pass, San Antonio, TX 78234 USA. NR 23 TC 2 Z9 2 U1 0 U2 0 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 1559-047X J9 J BURN CARE RES JI J. Burn Care Res. PD JAN-FEB PY 2013 VL 34 IS 1 BP 115 EP 119 DI 10.1097/BCR.0b013e318269be4a PG 5 WC Emergency Medicine; Dermatology; Surgery SC Emergency Medicine; Dermatology; Surgery GA 068IH UT WOS:000313359400027 PM 23292579 ER PT J AU Fletcher, JL Caterson, EJ Hale, RG Cancio, LC Renz, EM Chan, RK AF Fletcher, John L. Caterson, E. J. Hale, Robert G. Cancio, Leopoldo C. Renz, Evan M. Chan, Rodney K. TI Characterization of Skin Allograft Use in Thermal Injury SO JOURNAL OF BURN CARE & RESEARCH LA English DT Article ID DONOR SKIN; TRANSPLANTATION; BURNS AB This study provides objective data on the practice of allograft usage in severely burned patients. Furthermore, gaps in our knowledge are identified, and areas for further research are delineated. Using an institutional review board-approved protocol, active duty military patients injured while deployed in support of overseas contingency operations and treated at our burn center between March 2003 and December 2010 were identified. Their electronic medical records were reviewed for allograft use, TBSA burned, injury severity score, anatomic distribution of burns, operative burden, length of stay, transfusions, and outcome. Among 844 patients, 112 (13.3%) received allograft and 732 (86.7%) did not. The amount of allograft used per patient varied and was not normally distributed (median, 23.5; interquartile range, 69.5). Patients received allograft skin an average of 12.75 times during their admission. Allografted patients sustained severe burns (mu, 53.8% TBSA); most were transfused (71.2%) and grafted frequently, averaging every 7.45 days. Most commonly, allograft was placed on the extremities (66.5%) followed by the trunk (44.2%); however, the vast majority of allografted patients also had concomitant burns of the head (91.1%) and hands (87.5%). All-cause mortality among the allografted patients was 19.1%. In conclusion, allograft is commonly used in the surgical treatment of severe burns. Although there are no anatomic limitations to allograft placement, there are distinct patterns of use. Given the role of allograft in the acute management of large burns, there is need for further investigation of its effect on mortality, morbidity, and antigenicity. (J Burn Care Res 2013;34:168-175) C1 [Fletcher, John L.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA. [Fletcher, John L.; Cancio, Leopoldo C.; Renz, Evan M.; Chan, Rodney K.] USA, Inst Surg Res, Clin Div, Ft Sam Houston, TX 78234 USA. [Fletcher, John L.; Cancio, Leopoldo C.; Renz, Evan M.; Chan, Rodney K.] USA, Inst Surg Res, Burn Ctr, Ft Sam Houston, TX 78234 USA. [Caterson, E. J.] Brigham & Womens Hosp, Dept Plast Surg, Boston, MA 02115 USA. RP Chan, RK (reprint author), USA, Inst Surg Res, Clin Div, 3650 Chambers Pass, Ft Sam Houston, TX 78234 USA. EM rodney.k.chan@us.army.mil FU U.S. Army Medical Research and Materiel Command FX Supported by funds from the U.S. Army Medical Research and Materiel Command. NR 23 TC 5 Z9 5 U1 0 U2 4 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 1559-047X J9 J BURN CARE RES JI J. Burn Care Res. PD JAN-FEB PY 2013 VL 34 IS 1 BP 168 EP 175 DI 10.1097/BCR.0b013e318270000f PG 8 WC Emergency Medicine; Dermatology; Surgery SC Emergency Medicine; Dermatology; Surgery GA 068IH UT WOS:000313359400034 PM 23292585 ER PT J AU Shields, BA Doty, KA Chung, KK Wade, CE Aden, JK Wolf, SE AF Shields, Beth A. Doty, Kevin A. Chung, Kevin K. Wade, Charles E. Aden, James K. Wolf, Steven E. TI Determination of Resting Energy Expenditure After Severe Burn SO JOURNAL OF BURN CARE & RESEARCH LA English DT Article ID THERMALLY-INJURED PATIENTS; AMBIENT-TEMPERATURE; METABOLIC-RATE; REQUIREMENTS AB The purpose of this study was to evaluate the accuracy of nine predictive equations for calculating energy expenditure in severely burned adult subjects. The selected equations have been reported as commonly used or determined to be the most accurate. This prospective, observational study was conducted on adult subjects admitted between October 2007 and July 2010 with >= 20% TBSA full-thickness burns (excluding electrical burns or severe head injury). Indirect calorimetry measurements were conducted as a convenience sample during the first 30 days after injury. Demographic data were collected, and resting energy expenditure was calculated using the nine selected predictive equations and compared to measured energy expenditure (MEE) using descriptive and comparative statistics. Data were collected on 31 subjects with an average age of 46 +/- 19 years and %TBSA burn of 48 +/- 21%. For all equations, slopes and intercepts were significantly different from the line of identity when compared with MEE. A calorie-dependent bias was present for all equations, in that lower calorie range was overestimated and the higher calorie range was underestimated. Only the Carlson and Milner equations had results that were not significantly different from the MEE and mean differences that were not significant in all burn size ranges. None of the equations had a strong correlation with MEE. Of the equations available, the Milner and Carlson equations are the most satisfactory in predicting resting energy expenditure in severely burned adults when indirect calorimetry is unavailable. (J Burn Care Res 2013;34:e22-e28) C1 [Shields, Beth A.; Doty, Kevin A.; Chung, Kevin K.; Wade, Charles E.; Aden, James K.; Wolf, Steven E.] USA, Dept Med Nutr, San Antonio Mil Med Ctr, Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Wade, Charles E.] Univ Texas Hlth Sci Ctr, Dept Surg, Ctr Translat Injury Res, Houston, TX USA. [Wolf, Steven E.] Univ Texas SW Med Ctr Dallas, Dept Surg, Dallas, TX 75390 USA. RP Shields, BA (reprint author), USA, Burn Ctr, Inst Surg Res, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA. OI Wolf, Steven/0000-0003-2972-3440 FU National Institutes of Health [1 R01 GM063120-04]; Technologies for Metabolic Monitoring (TMM)/Julia Weaver Fund FX Supported by the National Institutes of Health (1 R01 GM063120-04) and the Technologies for Metabolic Monitoring (TMM)/Julia Weaver Fund, a congressionally directed program jointly managed by the USA MRMC, NIH, NASA, and the Juvenile Diabetes Research Foundation and Combat Casualty Care Division US Army Medical Research and Materiel Command. NR 19 TC 6 Z9 7 U1 1 U2 6 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 1559-047X J9 J BURN CARE RES JI J. Burn Care Res. PD JAN-FEB PY 2013 VL 34 IS 1 BP E22 EP E28 DI 10.1097/BCR.0b013e318254d2d5 PG 7 WC Emergency Medicine; Dermatology; Surgery SC Emergency Medicine; Dermatology; Surgery GA 068IH UT WOS:000313359400004 PM 22868454 ER PT J AU Williams, JF King, BT Aden, JK Serio-Melvin, M Chung, KK Fenrich, CA Salinas, J Renz, EM Wolf, SE Blackbourne, LH Cancio, LC AF Williams, James F. King, Booker T. Aden, James K. Serio-Melvin, Maria Chung, Kevin K. Fenrich, Craig A. Salinas, Jose Renz, Evan M. Wolf, Steven E. Blackbourne, Lorne H. Cancio, Leopoldo C. TI Comparison of Traditional Burn Wound Mapping With a Computerized Program SO JOURNAL OF BURN CARE & RESEARCH LA English DT Article; Proceedings Paper CT Canadian-Special-Interest-Group Meeting at the 43rd Annual Meeting of the American-Burn-Association (ABA) CY MAR 28-APR 01, 2011 CL Chicago, IL SP Amer Burn Assoc (ABA), Canadian Special Interest Grp ID SIZE; ACCURACY; NINES; CHART; MODEL; RULE; TOOL AB Accurate burn estimation affects the use of burn resuscitation formulas and treatment strategies, and thus can affect patient outcomes. The objective of this process-improvement project was to compare the accuracy of a computer-based burn mapping program, Wound-Flow (WF), with the widely used hand-mapped Lund-Browder (LB) diagram. Manikins with various burn representations (from 1% to more than 60% TBSA) were used for comparison of the WF system and LB diagrams. Burns were depicted on the manikins using red vinyl adhesive. Healthcare providers responsible for mapping of burn patients were asked to perform burn mapping of the manikins. Providers were randomized to either an LB or a WF group. Differences in the total map area between groups were analyzed. Also, direct measurements of the burn representations were taken and compared with LB and WF results. The results of 100 samples, compared using Bland-Altman analysis, showed no difference between the two methods. WF was as accurate as LB mapping for all burn surface areas. WF may be additionally beneficial in that it can track daily progress until complete wound closure, and can automatically calculate burn size, thus decreasing the chances of mathematical errors. (J Burn Care Res 2013;34:e29-e35) C1 [Williams, James F.; King, Booker T.; Aden, James K.; Serio-Melvin, Maria; Chung, Kevin K.; Fenrich, Craig A.; Salinas, Jose; Renz, Evan M.; Wolf, Steven E.; Blackbourne, Lorne H.; Cancio, Leopoldo C.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. RP King, BT (reprint author), USA, Inst Surg Res, 3698 Chambers Pass, Houston, TX 78234 USA. EM booker.king@us.army.mil OI Wolf, Steven/0000-0003-2972-3440 NR 22 TC 11 Z9 11 U1 2 U2 11 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 1559-047X J9 J BURN CARE RES JI J. Burn Care Res. PD JAN-FEB PY 2013 VL 34 IS 1 BP E29 EP E35 DI 10.1097/BCR.0b013e3182676e07 PG 7 WC Emergency Medicine; Dermatology; Surgery SC Emergency Medicine; Dermatology; Surgery GA 068IH UT WOS:000313359400005 PM 23292593 ER PT J AU East, EW Nisbet, N Liebich, T AF East, E. William Nisbet, Nicholas Liebich, Thomas TI Facility Management Handover Model View SO JOURNAL OF COMPUTING IN CIVIL ENGINEERING LA English DT Article DE Building information model; BIM; Model view definition; MVD; Industry foundation class; IFC; Construction handover; Facility management; Construction-operations building information exchange; COBie AB Current specifications for facility handover information require contractors to produce and deliver a set of documents that provide little practical value to the facility manager. Facility managers begin their duties by rekeying the information found in these handover documents. This paper describes the facility management handover (FM) model view definition (MVD), an open-standard information exchange format that may replace current construction handover document requirements. The work was accomplished in conjunction with three buildingSMART chapters to ensure the widest possible international acceptance. The specification of the underlying industry foundation class (IFC) model with required business rules for use in the United States is called the construction-operations building information exchange (COBie) format. Procedures used to test software production and consumption of COBie were developed. Use of COBie has now been documented in several case studies. DOI: 10.1061/(ASCE)CP.1943-5487.0000196. (C) 2013 American Society of Civil Engineers. C1 [East, E. William] Engn Res & Dev Ctr, Champaign, IL 61826 USA. [Nisbet, Nicholas] AEC3 Ltd, London, England. [Liebich, Thomas] AEC3 Deutschland GmbH, D-80634 Munich, Germany. RP East, EW (reprint author), Engn Res & Dev Ctr, 2902 Newmark Dr, Champaign, IL 61826 USA. EM bill.east@us.army.mil; nn@aec3.com; thomas.liebich@aec3.de NR 25 TC 17 Z9 18 U1 4 U2 73 PU ASCE-AMER SOC CIVIL ENGINEERS PI RESTON PA 1801 ALEXANDER BELL DR, RESTON, VA 20191-4400 USA SN 0887-3801 J9 J COMPUT CIVIL ENG JI J. Comput. Civil. Eng. PD JAN-FEB PY 2013 VL 27 IS 1 BP 61 EP 67 DI 10.1061/(ASCE)CP.1943-5487.0000196 PG 7 WC Computer Science, Interdisciplinary Applications; Engineering, Civil SC Computer Science; Engineering GA 067KR UT WOS:000313293400007 ER PT J AU Platten, WE Bailey, D Suidan, MT Maloney, SW AF Platten, William E., III Bailey, David Suidan, Makram T. Maloney, Stephen W. TI Treatment of Energetic Wastewater Containing 2,4-Dinitroanisole and N-Methyl Paranitro Aniline SO JOURNAL OF ENVIRONMENTAL ENGINEERING-ASCE LA English DT Article DE Explosives; Fluidized bed technology; Anaerobic treatment; Transformation ID ANAEROBIC TREATMENT; DNAN AB The U. S. Army is seeking to produce safer, less sensitive munitions through the addition of two new energetics, 2,4-dinitroanisole (DNAN) and N-methyl paranitro aniline (MNA), to the munitions' formula. Production of these munitions would add them to the waste stream. The use of an anaerobic fluidized-bed bioreactor (AFBB) was studied for treating these compounds in a simulated wastewater with ethanol as the electron donor. The reactor degraded both of the compounds to below detection limits over a wide range of ethanol concentrations. The degradation was found to be a transformation into secondary products for both energetics: diaminoanisole (for DNAN) and N-methyl-p-phenylenediamine (for MNA). Both of these by-products reacted upon exposure to air, forming azobond dimers. Potassium perchlorate was added to the feed stream to test if additional energetics would disrupt the transformation. The AFBB continued transformation and was able to remove the perchlorate after a two week acclimation period. The AFBB was an effective treatment method for DNAN and MNA, but further study is required to investigate the transformation products more thoroughly. DOI: 10.1061/(ASCE)EE.1943-7870.0000592. (C) 2013 American Society of Civil Engineers. C1 [Platten, William E., III; Bailey, David; Suidan, Makram T.] Univ Cincinnati, Dept Civil & Environm Engn, Cincinnati, OH 45221 USA. [Maloney, Stephen W.] USA, Construct Engn Res Lab, Engn Res & Dev Ctr, Champaign, IL 61826 USA. RP Platten, WE (reprint author), Univ Cincinnati, Dept Civil & Environm Engn, Cincinnati, OH 45221 USA. EM plattewe@mail.uc.edu NR 14 TC 1 Z9 1 U1 3 U2 43 PU ASCE-AMER SOC CIVIL ENGINEERS PI RESTON PA 1801 ALEXANDER BELL DR, RESTON, VA 20191-4400 USA SN 0733-9372 J9 J ENVIRON ENG-ASCE JI J. Environ. Eng.-ASCE PD JAN PY 2013 VL 139 IS 1 BP 104 EP 109 DI 10.1061/(ASCE)EE.1943-7870.0000592 PG 6 WC Engineering, Environmental; Engineering, Civil; Environmental Sciences SC Engineering; Environmental Sciences & Ecology GA 069IJ UT WOS:000313428200012 ER PT J AU Zander, NE Orlicki, JA Rawlett, AM Beebe, TP AF Zander, Nicole E. Orlicki, Joshua A. Rawlett, Adam M. Beebe, Thomas P., Jr. TI Electrospun polycaprolactone scaffolds with tailored porosity using two approaches for enhanced cellular infiltration SO JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE LA English DT Article ID IN-VITRO; EXTRACELLULAR-MATRIX; NANOFIBER SCAFFOLD; GAMMA-IRRADIATION; NEURITE OUTGROWTH; TISSUE; FIBERS; DIAMETER; COLLAGEN; FIBROBLASTS AB The impact of mat porosity of polycaprolactone (PCL) electrospun fibers on the infiltration of neuron-like PC12 cells was evaluated using two different approaches. In the first method, bi-component aligned fiber mats were fabricated via the co-electrospinning of PCL with polyethylene oxide (PEO). Variation of the PEO flow rate, followed by selective removal of PEO from the PCL/PEO mesh, allowed for control of the porosity of the resulting scaffold. In the second method, aligned fiber mats were fabricated from various concentrations of PCL solutions to generate fibers with diameters between 0.13 +/- A 0.06 and 9.10 +/- A 4.1 mu m. Of the approaches examined, the variation of PCL fiber diameter was found to be the better method for increasing the infiltration of PC12 cells, with the optimal infiltration into the ca. 1.5-mm-thick meshes observed for the mats with the largest fiber diameters, and hence largest pore sizes. C1 [Zander, Nicole E.; Orlicki, Joshua A.; Rawlett, Adam M.] USA, Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. [Zander, Nicole E.; Beebe, Thomas P., Jr.] Univ Delaware, Dept Chem & Biochem, Newark, DE 19716 USA. RP Zander, NE (reprint author), USA, Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA. EM nicole.e.zander.civ@mail.mil NR 42 TC 12 Z9 12 U1 3 U2 85 PU SPRINGER PI DORDRECHT PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS SN 0957-4530 J9 J MATER SCI-MATER M JI J. Mater. Sci.-Mater. Med. PD JAN PY 2013 VL 24 IS 1 BP 179 EP 187 DI 10.1007/s10856-012-4771-7 PG 9 WC Engineering, Biomedical; Materials Science, Biomaterials SC Engineering; Materials Science GA 068LT UT WOS:000313368900018 PM 23053801 ER PT J AU Odle-Dusseau, HN Herleman, HLA Britt, TW Moore, DD Castro, CA McGurk, D AF Odle-Dusseau, Heather N. Herleman, Hai Ley A. Britt, Thomas W. Moore, DeWayne D. Castro, Carl A. McGurk, Dennis TI Family-Supportive Work Environments and Psychological Strain: A Longitudinal Test of Two Theories SO JOURNAL OF OCCUPATIONAL HEALTH PSYCHOLOGY LA English DT Article DE family-supportive work environments; well-being; military families; reciprocal relationships; longitudinal methods ID STRUCTURAL EQUATION MODEL; DEMANDS-RESOURCES MODEL; JOB DEMANDS; MENTAL-HEALTH; ORGANIZATIONAL PERCEPTIONS; RECIPROCAL RELATIONSHIPS; CONFLICT; STRESS; ATTITUDES; IRAQ AB Based on the Job Demands-Resources (JDR) model (E. Demerouti, A. B. Bakker, F. Nachreiner, & W. B. Schaufeli, 2001, The job demands-resources model of burnout. Journal of Applied Psychology, 86, 499-512) and Conservation of Resources (COR) theory (S. E. Hobfoll, 2002, Social and psychological resources and adaptation. Review of General Psychology, 6, 307-324), we tested three competing models that predict different directions of causation for relationships over time between family-supportive work environments (FSWE) and psychological strain, with two waves of data from a military sample. Results revealed support for both the JDR and COR theories, first in the static model where FSWE at Time predicted psychological strain at Time 2 and when testing the opposite direction, where psychological strain at Time 1 predicted FSWE at Time 2. For change models, FSWE predicted changes in psychological strain across time, although the reverse causation model was not supported (psychological strain at Time 1 did not predict changes in FSWE). Also, changes in FSWE across time predicted psychological strain at Time 2, whereas changes in psychological strain did not predict FSWE at Time 2. Theoretically, these results are important for the work family interface in that they demonstrate the application of a systems approach to studying work and family interactions, as support was obtained for both the JDR model with perceptions of FSWE predicting psychological strain (in both the static and change models), and for COR theory where psychological strain predicts FSWE across time. C1 [Odle-Dusseau, Heather N.] Gettysburg Coll, Dept Management, Gettysburg, PA 17325 USA. [Herleman, Hai Ley A.] Kenexa, Wayne, PA USA. [Britt, Thomas W.; Moore, DeWayne D.] Clemson Univ, Dept Psychol, Clemson, SC 29631 USA. [Castro, Carl A.] Med Res & Mat Command, Mil Operat Med Res Program, Frederick, MD USA. [McGurk, Dennis] Walter Reed Army Inst Res, US Army Med Res Unit Europe, Heidelberg, Germany. RP Odle-Dusseau, HN (reprint author), Gettysburg Coll, Dept Management, 300 N Washington St,Box 395, Gettysburg, PA 17325 USA. EM hodle@gettysburg.edu NR 59 TC 10 Z9 10 U1 5 U2 51 PU AMER PSYCHOLOGICAL ASSOC PI WASHINGTON PA 750 FIRST ST NE, WASHINGTON, DC 20002-4242 USA SN 1076-8998 J9 J OCCUP HEALTH PSYCH JI J. Occup. Health Psychol. PD JAN PY 2013 VL 18 IS 1 BP 27 EP 36 DI 10.1037/a0030803 PG 10 WC Public, Environmental & Occupational Health; Psychology, Applied SC Public, Environmental & Occupational Health; Psychology GA 068UO UT WOS:000313391900004 PM 23276196 ER PT J AU Bristow, E Reese, M DeRocchi, M AF Bristow, Elizabeth Reese, Morgan DeRocchi, Mark TI Fostering Current Student Relationships to Promote Graduate Reachback: Collaborative Student and Faculty Development following the 2010 Haiti Earthquake SO JOURNAL OF PROFESSIONAL ISSUES IN ENGINEERING EDUCATION AND PRACTICE LA English DT Article C1 [Bristow, Elizabeth; Reese, Morgan; DeRocchi, Mark] US Mil Acad, Dept Civil & Mech Engn, West Point, NY 10996 USA. RP Bristow, E (reprint author), US Mil Acad, Dept Civil & Mech Engn, West Point, NY 10996 USA. EM Elizabeth.bristow@us.army.mil; Morgan.Reese@us.army.mil; mark.derocchi@us.army.mil NR 17 TC 0 Z9 0 U1 0 U2 2 PU ASCE-AMER SOC CIVIL ENGINEERS PI RESTON PA 1801 ALEXANDER BELL DR, RESTON, VA 20191-4400 USA SN 1052-3928 J9 J PROF ISS ENG ED PR JI J. Prof. Issues Eng. Educ. Pract. PD JAN PY 2013 VL 139 IS 1 BP 1 EP 4 DI 10.1061/(ASCE)EI.1943-5541.0000122 PG 4 WC Education, Scientific Disciplines; Engineering, Multidisciplinary SC Education & Educational Research; Engineering GA 069CY UT WOS:000313414000001 ER PT J AU Liu, YH Zhang, W Zhu, YJ Luo, YT Xu, YH Brown, A Culver, JN Lundgren, CA Xu, K Wang, Y Wang, CS AF Liu, Yihang Zhang, Wei Zhu, Yujie Luo, Yanting Xu, Yunhua Brown, Adam Culver, James N. Lundgren, Cynthia A. Xu, Kang Wang, Yuan Wang, Chunsheng TI Architecturing Hierarchical Function Layers on Self-Assembled Viral Templates as 3D Nano-Array Electrodes for Integrated Li-Ion Microbatteries SO NANO LETTERS LA English DT Article DE 3D microbattery arrays; nanohierarchy; tobacco mosaic virus; integral power for microelectronics; LiFePO4 nanoforests; magnetron sputtering ID LIFEPO4 THIN-FILM; CARBON NANOFIBERS; BATTERIES; CATHODES; DEPOSITION; PERFORMANCE; SHELL; ANODE AB This work enables an elegant bottom-up solution to engineer 3D microbattery arrays as integral power sources for microelectronics. Thus, multilayers of functional materials were hierarchically architectured over tobacco mosaic virus (TMV) templates that were genetically modified to self-assemble in a vertical manner on current-collectors, so that optimum power and energy densities accompanied with excellent cycle-life could be achieved on a minimum footprint. The resultant microbattery based on self-aligned LiFePO4 nanoforests of shell-core-shell structure, with precise arrangement of various auxiliary material layers including a central nanometric metal core as direct electronic pathway to current collector, delivers excellent energy density and stable cycling stability only rivaled by the best Li-ion batteries of conventional configurations, while providing rate performance per foot-print and on-site manufacturability unavailable from the latter. This approach could open a new avenue for microelectromechanical systems (MEMS) applications, which would significantly benefit from the concept that electrochemically active components be directly engineered and fabricated as an integral part of the integrated circuit (IC). C1 [Liu, Yihang; Zhu, Yujie; Luo, Yanting; Xu, Yunhua; Wang, Chunsheng] Univ Maryland, Dept Chem & Biomol Engn, College Pk, MD 20742 USA. [Zhang, Wei; Wang, Yuan] Sichuan Univ, Inst Nucl Sci & Technol, Minist Educ, Key Lab Radiat Phys & Technol, Chengdu 610064, Peoples R China. [Brown, Adam; Culver, James N.] Univ Maryland, Dept Plant Sci & Landscape Architecture, College Pk, MD 20742 USA. [Brown, Adam; Culver, James N.] Univ Maryland, Inst Biosci & Biotechnol Res, College Pk, MD 20742 USA. [Lundgren, Cynthia A.; Xu, Kang] USA, Electrochem Branch, Power & Energy Div Sensor, Res Lab, Adelphi, MD 20783 USA. [Lundgren, Cynthia A.; Xu, Kang] USA, Electron Devices Directorate, Res Lab, Adelphi, MD 20783 USA. RP Xu, K (reprint author), USA, Electrochem Branch, Power & Energy Div Sensor, Res Lab, Adelphi, MD 20783 USA. EM conrad.k.xu.civ@mail.mil; wyuan@scu.edu; cswang@umd.edu RI Wang, Chunsheng/H-5767-2011; Xu, Yunhua/D-7751-2012; Liu, Yihang/E-6958-2013 OI Wang, Chunsheng/0000-0002-8626-6381; Liu, Yihang/0000-0002-2491-9439 FU U.S. Army Research Laboratory; National Natural Science Foundation of China [51171124]; Program for New Century Excellent Talents in University [NCET-08-0380] FX The authors acknowledge financial support from the U.S. Army Research Laboratory and the technical support of the Maryland NanoCenter. We thank Dr. Li-Chung Lai and Fangyu Cao for the TEM and SEM imaging, Yanmei Piao for collecting the Raman data, Jiangwei Wang for indexing the SAD figure. Dr. Yuan Wang would like to acknowledge the financial support from the National Natural Science Foundation of China (Grant Nu. 51171124) and the Program for New Century Excellent Talents in University (Grant No. NCET-08-0380) NR 26 TC 30 Z9 32 U1 12 U2 251 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN 1530-6984 EI 1530-6992 J9 NANO LETT JI Nano Lett. PD JAN PY 2013 VL 13 IS 1 BP 293 EP 300 DI 10.1021/nl304104q PG 8 WC Chemistry, Multidisciplinary; Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter SC Chemistry; Science & Technology - Other Topics; Materials Science; Physics GA 065IP UT WOS:000313142300050 PM 23252613 ER PT J AU Li, XN Fallon, J Egge, N Curry, EJ Patel, K Owens, BD Busconi, BD AF Li, Xinning Fallon, Jonathan Egge, Natalie Curry, Emily J. Patel, Ketan Owens, Brett D. Busconi, Brian D. TI MRI Study of Associated Shoulder Pathology in Patients With Full-thickness Subscapularis Tendon Tears SO ORTHOPEDICS LA English DT Article ID ROTATOR CUFF TEARS; SUPRASPINATUS MUSCLE; ISOLATED RUPTURE; REPAIR; ATROPHY; STABILIZATION; DEGENERATION; IMPINGEMENT; HEAD AB Subscapularis tendon tears are a well-established cause of shoulder pain. The objective of the current study was to evaluate the associated shoulder pathology in patients with full-thickness subscapularis tendon tears using magnetic resonance imaging. Forty-seven magnetic resonance imaging studies taken between 2008 and 2009 with a diagnosis of full-thickness subscapularis tendon tears were reviewed. The size of the subscapularis tendon tear, amount of muscle volume loss, Goutallier grade, biceps tendon pathology, coracohumeral distance, and associated rotator cuff tears were recorded. Statistical analysis was performed. Patients 55 years and older vs those 54 years and younger had an average subscapularis tear size of 35 vs 19 mm, an average Goutallier grade of 2.7 vs 0.8, and a total muscle volume loss of 25% vs 5%, respectively. Patients with a dislocated vs normal biceps tendons had an average subscapularis tear size of 37 vs 23 mm, an average Goutallier grade of 3 vs 0.9, and a total muscle volume loss of 28% vs 7%, respectively. Patients with vs without concomitant rotator cuff tears had an average subscapularis tear size of 32 vs 17 mm, an average Goutallier grade of 2.3 vs 0.6, and a total muscle volume loss of 21% vs 3%, respectively. Overall average coracohumeral distance measured in the axial plane was 10.8+/-4.6 mm. Average coracaohumeral distance was 14.8 vs 8.1 mm in patients with a Goutallier grade of 0 vs 3 or 4, resepectively, and 13.6 vs 8.5 mm in patients with no rotator cuff tear vs those with a supra-and infraspinatus tear, respectively. Increased age, dislocated biceps tendons, and concomitant rotator cuff tears in patients with full-thickness subscapularis tendon tears are associated with larger subscapularis tendon tear size, higher Goutallier grades, and increased subscapularis muscle volume loss. Decreased coracohumeral distance is associated with a higher Goutallier grade and rotator cuff tears. C1 [Li, Xinning; Fallon, Jonathan; Egge, Natalie; Curry, Emily J.; Patel, Ketan; Busconi, Brian D.] Univ Massachusetts, Med Ctr, Dept Orthopaed Surg, Worcester, MA 01655 USA. [Owens, Brett D.] Keller Army Community Hosp, Orthopaed Surg Serv, West Point, NY USA. RP Li, XN (reprint author), Univ Massachusetts, Med Ctr, Dept Orthopaed Surg, Room S4-827,55 Lake Ave N, Worcester, MA 01655 USA. EM xinning.li@gmail.com NR 25 TC 1 Z9 1 U1 0 U2 5 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 USA SN 0147-7447 J9 ORTHOPEDICS JI Orthopedics PD JAN PY 2013 VL 36 IS 1 BP E44 EP E50 DI 10.3928/01477447-20121217-17 PG 7 WC Orthopedics SC Orthopedics GA 068DJ UT WOS:000313344400008 PM 23276351 ER PT J AU See, A Bear, RR Owens, BD AF See, Aaron Bear, Russell R. Owens, Brett D. TI Anatomic Mapping for Surgical Reconstruction of the Proximal Tibiofibular Ligaments SO ORTHOPEDICS LA English DT Article ID RECURRENT DISLOCATIONS; JOINT INSTABILITY; PERONEAL-NERVE; KNEE-JOINT; SUBLUXATION; FRACTURE; TENDON; CYST AB Injury to the proximal tibiofibular joint is uncommon. Previous studies regarding the anatomy of this region have predominantly focused on joint orientation. As radiographic technology has advanced, later studies have attempted to evaluate the capsular anatomy. However, no reports specifically map the ligaments to this joint. The objectives of the current study were to define specific ligamentous structures that provide stability to the proximal tibiofibular joint, describe easily identifiable and reproducible surgical landmarks to aid in surgical reconstruction, and add to the understanding of the posterolateral structures of the knee previously described by other authors. The proximal tibiofibular joint ligaments were identified in 10 fresh-frozen cadaveric specimens. Average ligament length, width, and thickness and area of the footprints of the tibial and fibular attachments were measured. Distances from the ligament footprints to known anatomic landmarks (eg, Gerdy's tubercle, tibial articular surface, and fibular styloid) were also measured. The anterior ligament tibial attachment was a mean of 15.6 mm lateral and posterior to Gerdy's tubercle and 17.3 mm anterior and inferior from the fibular styloid. Posterior ligament tibial insertion was a mean of 15.7 mm inferior to the tibial articular surface on the tibial side and 14.2 mm medial and slightly inferior from the fibular styloid. Definable ligaments provide stability to the proximal tibiofibular joint and can be reconstructed in an anatomic fashion using the landmarks and parameters described. This information allows for an anatomic reconstruction of the proximal tibiofibular joint, which should provide patients with better outcomes and fewer postoperative sequelae. C1 [See, Aaron] William Beaumont Army Med Ctr, Dept Orthopaed Surg, El Paso, TX 79920 USA. [Bear, Russell R.] 3B Orthopaed PC, Philadelphia, PA 19107 USA. [Owens, Brett D.] Keller Army Community Hosp, Dept Orthopaed Surg, West Point, NY USA. RP Bear, RR (reprint author), 3B Orthopaed PC, 800 Spruce St,8th Floor,Cathcart Bldg, Philadelphia, PA 19107 USA. EM rbear0948@yahoo.com NR 44 TC 5 Z9 5 U1 0 U2 10 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 USA SN 0147-7447 J9 ORTHOPEDICS JI Orthopedics PD JAN PY 2013 VL 36 IS 1 BP E58 EP E63 DI 10.3928/01477447-20121217-19 PG 6 WC Orthopedics SC Orthopedics GA 068DJ UT WOS:000313344400010 PM 23276353 ER PT J AU Mansoor, GF Rahmani, AM Kakar, MA Hashimy, P Abrahimi, P Scott, PT Peel, SA Rentas, FJ Todd, CS AF Mansoor, G. Farooq Rahmani, Ahmad Masoud Kakar, M. Aziz Hashimy, Pashtoon Abrahimi, Parwiz Scott, Paul T. Peel, Sheila A. Rentas, Francisco J. Todd, Catherine S. TI A national mapping assessment of blood collection and transfusion service facilities in Afghanistan SO TRANSFUSION LA English DT Article ID INFECTIONS; SAFETY; STATES; KENYA AB BACKGROUND: The purpose of this study was to assess functionality and resources of facilities providing blood collection and transfusion services in Afghanistan. STUDY DESIGN AND METHODS: This national cross-sectional assessment included facilities collecting or transfusing blood identified through official data sources and private key informants. At each facility, study representatives completed a standardized instrument assessing presence of records logbook, electricity, refrigeration, and required transfusion-transmitted infection (TTI; human immunodeficiency virus, syphilis, and hepatitis B and C) test kits. Descriptive statistics were generated, with differences analyzed using chi-square or Fisher's exact tests. RESULTS: Between August and November 2010, a total of 243 facilities were surveyed with public (52.3%, n = 127) and private (43.2%, n = 105) sector comprising the majority. Most (63%) facilities were urban, with 23.5% located in Kabul province. Of 92,682 units collected nationally in the 12 months before evaluation, 7.5% (n = 6952) had no disposition record. Many (62%, n = 151) facilities had an established recordkeeping system; the remainder provided estimates. Half of surveyed facilities had regular power supply (57.8%), refrigerators for storing blood (52.3%), or all necessary TTI test kits (62.1%). Military (83.3%) and public (74.8%) facilities were more likely to have all TTI test kits present compared to private (46.7%, p < 0.01) but not nongovernmental organization (40.0%, p = 0.37) facilities. CONCLUSION: In Afghanistan, blood donation and transfusion occur with substantial differences in data recording and TTI test availability, with private facilities less likely to have these resources. Efforts are needed to improve available resources and ensure that facilities are in compliance with national standards for donor screening. C1 Minist Publ Hlth, Afghan Natl Blood Safety & Transfus Serv, Kabul, Afghanistan. Yale Univ, Sch Med, New Haven, CT USA. Walter Reed Army Inst Res, US Mil HIV Res Program, Bethesda, MD USA. US Dept Def, Armed Serv Blood Program Off, Falls Church, VA USA. Columbia Univ, Dept Obstet & Gynecol, New York, NY USA. RP Todd, CS (reprint author), 16-69,622 W 168 St, New York, NY 10032 USA. EM cst2121@columbia.edu FU Military Infectious Disease Research Program; Armed Services Blood Program FX Funded by the Military Infectious Disease Research Program and Armed Services Blood Program. NR 27 TC 2 Z9 2 U1 0 U2 2 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0041-1132 J9 TRANSFUSION JI Transfusion PD JAN PY 2013 VL 53 IS 1 BP 69 EP 75 DI 10.1111/j.1537-2995.2012.03674.x PG 7 WC Hematology SC Hematology GA 068ET UT WOS:000313348900012 PM 22554200 ER PT J AU Dumont, LJ Cancelas, JA Dumont, DF Siegel, AH Szczepiorkowski, ZM Rugg, N Pratt, PG Worsham, DN Hartman, EL Dunn, SK O'Leary, M Ransom, JH Michael, RA Macdonald, V AF Dumont, Larry J. Cancelas, Jose A. Dumont, Deborah F. Siegel, Alan H. Szczepiorkowski, Zbigniew M. Rugg, Neeta Pratt, P. Gayle Worsham, D. Nicole Hartman, Elizabeth L. Dunn, Susan K. O'Leary, Margaret Ransom, Janet H. Michael, Rodney A. Macdonald, VictorW. TI A randomized controlled trial evaluating recovery and survival of 6% dimethyl sulfoxide-frozen autologous platelets in healthy volunteers SO TRANSFUSION LA English DT Article ID FREEZING HUMAN PLATELETS; TRAUMA PATIENTS; TRANSFUSION; BLOOD; STORAGE; EXPERIENCE; VIABILITY; TESTS AB BACKGROUND: Availability of platelets (PLTs) is severely limited by shelf life in some settings. Our objective was to determine and compare to Food and Drug Administration (FDA) criteria the PLT recovery and survival of autologous PLTs cryopreserved at -65 degrees C or less in 6% dimethyl sulfoxide (DMSO) reconstituted with a no-wash method (cryopreserved PLTs [CPPs]) compared to autologous fresh PLTs. STUDY DESIGN AND METHODS: This was a randomized, Phase I study analyzing PLT viability and in vitro function in consenting healthy subjects. Apheresis PLTs (APs) were collected in plasma. APs were suspended in 6% DMSO, concentrated, and placed at not more than -65 degrees C for 7 to 13 days. Frozen CPPs were thawed at 37 degrees C and resuspended into 25 mL of 0.9% NaCl. Control PLTs (fresh autologous) and CPPs were labeled with 111In or 51Cr, and recovery and survival after reinfusion were determined using standard methods. A panel of in vitro assays was completed on APs and CPPs. RESULTS: After frozen storage, CPPs retained 82% of AP yield and showed increased PLT associated P-selectin and reduced responses to agonists. CPP 24-hour recovery (41.6 +/- 9.7%) was lower than for fresh PLTs (68.4 +/- 8.2%; p < 0.0001) and did not meet the current FDA criterion. CPPs had diminished survival compared to fresh PLTs (7.0 +/- 2.1 days vs. 8.4 +/- 1.2 days, respectively; p = 0.018), but did meet and exceed the FDA criterion for survival. CONCLUSION: While 24-hour recovery does not meet FDA criteria for liquid-stored PLTs, the CPP survival of circulating PLTs was surprisingly high and exceeded the FDA criteria. These data support proceeding with additional studies to evaluate the clinical effectiveness of CPPs. C1 Geisel Sch Med Dartmouth, Lebanon, NH USA. [Dumont, Larry J.] Dartmouth Hitchcock Med Ctr, Ctr Transfus Med Res, Dept Pathol, Lebanon, NH 03756 USA. Univ Cincinnati, Hoxworth Blood Ctr, Cincinnati, OH USA. Fast Track Drugs & Biol LLC, Potomac, MD USA. US Army Med Mat Dev Act, Ft Detrick, MD USA. RP Dumont, LJ (reprint author), Dartmouth Hitchcock Med Ctr, Ctr Transfus Med Res, Dept Pathol, 1 Med Ctr Dr, Lebanon, NH 03756 USA. EM larry.j.dumont@hitchcock.org RI Szczepiorkowski, Zbigniew/A-1359-2007; Dumont, Larry/B-3994-2011 OI Szczepiorkowski, Zbigniew/0000-0003-2357-9564; Dumont, Larry/0000-0002-1715-0748 FU US Army Medical Research and Materiel Command [DAMD17-02-D-0002] FX This study was supported by the US Army Medical Research and Materiel Command under Contract No. DAMD17-02-D-0002. NR 29 TC 21 Z9 21 U1 0 U2 5 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0041-1132 J9 TRANSFUSION JI Transfusion PD JAN PY 2013 VL 53 IS 1 BP 128 EP 137 DI 10.1111/j.1537-2995.2012.03735.x PG 10 WC Hematology SC Hematology GA 068ET UT WOS:000313348900020 PM 22671278 ER PT J AU Cook, JB Shaha, JS Rowles, DJ Bottoni, CR Shaha, SH Tokish, JM AF Cook, Jay B. Shaha, James S. Rowles, Douglas J. Bottoni, Craig R. Shaha, Steven H. Tokish, John M. TI Clavicular Bone Tunnel Malposition Leads to Early Failures in Coracoclavicular Ligament Reconstructions SO AMERICAN JOURNAL OF SPORTS MEDICINE LA English DT Article DE acromioclavicular; coracoclavicular; early failures; reconstruction; bone tunnel ID ACROMIOCLAVICULAR JOINT DISLOCATIONS; TENDON GRAFT; INJURIES AB Background: Modern techniques for the treatment of acromioclavicular (AC) joint dislocations have largely centered on free tendon graft reconstructions. Recent biomechanical studies have demonstrated that an anatomic reconstruction with 2 clavicular bone tunnels more closely matches the properties of native coracoclavicular (CC) ligaments than more traditional techniques. No study has analyzed tunnel position in regard to risk of early failure. Purpose: To evaluate the effect of clavicular tunnel position in CC ligament reconstruction as a risk of early failure. Study Design: Case series; Level of evidence, 4. Methods: A retrospective review was performed of a consecutive series of CC ligament reconstructions performed with 2 clavicular bone tunnels and a free tendon graft. The population was largely a young, active-duty military group of patients. Radiographs were analyzed for the maintenance of reduction and location of clavicular bone tunnels using a picture archiving and communication system. The distance from the lateral border of the clavicle to the center of each bone tunnel was divided by the total clavicular length to establish a ratio. Medical records were reviewed for operative details and functional outcome. Failure was defined as loss of intraoperative reduction. Results: The overall failure rate was 28.6% (8/28) at an average of 7.4 weeks postoperatively. Comparison of bone tunnel position showed that medialized bone tunnels were a significant predictor for early loss of reduction for the conoid (a ratio of 0.292 vs 0.248; P = .012) and trapezoid bone tunnels (a ratio of 0.171 vs 0.128; P = .004); this correlated to an average of 7 to 9 mm more medial in the reconstructions that failed. Reconstructions performed with a conoid ratio of >= 0.30 were significantly more likely to fail (5/5, 100%) than were those performed lateral to a ratio of 0.30 (3/23, 13.0%) (P < .01). There were no failures when the conoid ratio was <0.25 (0/10, 0%). Conoid tunnel placement was also statistically significant for predicting return to duty in our active-duty population. Conclusion: Medial tunnel placement is a significant factor in risk for early failures when performing anatomic CC ligament reconstructions. Preoperative templating is recommended to evaluate optimal placement of the clavicular bone tunnels. Placement of the conoid tunnel at 25% of the clavicular length from the lateral border of the clavicle is associated with a lower rate of lost reduction and a higher rate of return to military duty. C1 [Cook, Jay B.; Shaha, James S.; Rowles, Douglas J.; Bottoni, Craig R.; Shaha, Steven H.; Tokish, John M.] Tripler Army Med Ctr, Honolulu, HI 96734 USA. RP Cook, JB (reprint author), Tripler Army Med Ctr, 1 Jarrett White Rd, Honolulu, HI 96734 USA. EM jaybcook@yahoo.com NR 22 TC 20 Z9 21 U1 0 U2 1 PU SAGE PUBLICATIONS INC PI THOUSAND OAKS PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA SN 0363-5465 J9 AM J SPORT MED JI Am. J. Sports Med. PD JAN PY 2013 VL 41 IS 1 BP 142 EP 148 DI 10.1177/0363546512465591 PG 7 WC Orthopedics; Sport Sciences SC Orthopedics; Sport Sciences GA 063OB UT WOS:000313008300020 PM 23139253 ER PT J AU Stojadinovic, A Bilchik, A Smith, D Eberhardt, JS Ben Ward, E Nissan, A Johnson, EK Protic, M Peoples, GE Avital, I Steele, SR AF Stojadinovic, Alexander Bilchik, Anton Smith, David Eberhardt, John S. Ben Ward, Elizabeth Nissan, Aviram Johnson, Eric K. Protic, Mladjan Peoples, George E. Avital, Itzhak Steele, Scott R. TI Clinical Decision Support and Individualized Prediction of Survival in Colon Cancer: Bayesian Belief Network Model SO ANNALS OF SURGICAL ONCOLOGY LA English DT Article ID US-POPULATION DATABASE; BREAST-CANCER; COLORECTAL-CANCER; RISK; IMPACT; RECURRENCE; STRATEGY; SURGERY; RATES AB We used a large population-based data set to create a clinical decision support system (CDSS) for real-time estimation of overall survival (OS) among colon cancer (CC) patients. Patients with CC diagnosed between 1969 and 2006 were identified from the Surveillance Epidemiology and End Results (SEER) registry. Low- and high-risk cohorts were defined. The tenfold cross-validation assessed predictive utility of the machine-learned Bayesian belief network (ml-BBN) model for clinical decision support (CDS). A data set consisting of 146,248 records was analyzed using ml-BBN models to provide CDS in estimating OS based on prognostic factors at 12-, 24-, 36-, and 60-month post-treatment follow-up. Independent prognostic factors in the ml-BBN model included age, race; primary tumor histology, grade and location; Number of primaries, AJCC T stage, N stage, and M stage. The ml-BBN model accurately estimated OS with area under the receiver-operating-characteristic curve of 0.85, thereby improving significantly upon existing AJCC stage-specific OS estimates. Significant differences in OS were found between low- and high-risk cohorts (odds ratios for mortality: 17.1, 16.3, 13.9, and 8.8 for 12-, 24-, 36-, and 60-month cohorts, respectively). A CDSS was developed to provide individualized estimates of survival in CC. This ml-BBN model provides insights as to how disease-specific factors influence outcome. Time-dependent, individualized mortality risk assessments may inform treatment decisions and facilitate clinical trial design. C1 [Stojadinovic, Alexander; Johnson, Eric K.; Peoples, George E.; Avital, Itzhak; Steele, Scott R.] Uniformed Serv Univ Hlth Sci, Dept Surg, Bethesda, MD 20814 USA. [Stojadinovic, Alexander; Bilchik, Anton; Nissan, Aviram; Johnson, Eric K.; Protic, Mladjan; Peoples, George E.; Steele, Scott R.] US Mil Canc Inst, Clin Trials Grp, Washington, DC USA. [Stojadinovic, Alexander] Walter Reed Natl Mil Med Ctr, Dept Surg, Div Surg Oncol, Bethesda, MD USA. [Smith, David] City Hope Natl Med Ctr, Div Biostat, Duarte, CA USA. [Eberhardt, John S.; Ben Ward, Elizabeth] DecisionQ Corp, Washington, DC USA. [Nissan, Aviram] Rabin Med Ctr, Dept Surg, Petah Tiqwa, Israel. [Avital, Itzhak] Bon Secours Canc Inst, Richmond, VA USA. [Bilchik, Anton] Univ Calif Los Angeles, Dept Med, Los Angeles, CA 90024 USA. [Bilchik, Anton] Calif Oncol Res Inst, Santa Monica, CA USA. [Johnson, Eric K.; Steele, Scott R.] Madigan Army Med Ctr, Dept Surg, Tacoma, WA 98431 USA. [Protic, Mladjan] Univ Novi Sad, Fac Med, Clin Abdominal Endocrine & Transplantat Surg, Clin Ctr Vojvodina, Novi Sad 21000, Serbia. [Peoples, George E.] Brooke Army Med Ctr, Dept Surg, San Antonio, TX USA. RP Stojadinovic, A (reprint author), Uniformed Serv Univ Hlth Sci, Dept Surg, Bethesda, MD 20814 USA. EM alexander.stojadinovic@med.navy.mil FU United States Military Cancer Institute, Washington, D.C.; Henry M. Jackson Foundation, Rockville, MD; RO1 Grant [CA090848] FX This clinical research effort was supported, in part, by the United States Military Cancer Institute, Washington, D.C. and the Henry M. Jackson Foundation, Rockville, MD and RO1 Grant CA090848. NR 32 TC 11 Z9 11 U1 4 U2 16 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1068-9265 J9 ANN SURG ONCOL JI Ann. Surg. Oncol. PD JAN PY 2013 VL 20 IS 1 BP 161 EP 174 DI 10.1245/s10434-012-2555-4 PG 14 WC Oncology; Surgery SC Oncology; Surgery GA 059MK UT WOS:000312709400025 PM 22899001 ER PT J AU Law, J Mathers, CH Fondy, SRE Vanderploeg, JM Kerstman, EL AF Law, Jennifer Mathers, Charles H. Fondy, Susan R. E. Vanderploeg, James M. Kerstman, Eric L. TI NASA's Human System Risk Management Approach and Its Applicability to Commercial Spaceflight SO AVIATION SPACE AND ENVIRONMENTAL MEDICINE LA English DT Article AB LAW J, MATHERS CH, FONDY SRE, VANDERPLOEG JM, KERSTMAN EL. NASA's human system risk management approach and its applicability to commercial spaceflight. Aviat Space Environ Med 2013; 84:68-73. As planning continues for commercial spaceflight, attention is turned to NASA to assess whether its human system risk management approach can be applied to mitigate the risks associated with commercial suborbital and orbital flights. NASA uses a variety of methods to assess the risks to the human system based on their likelihood and consequences. In this article, we review these methods and categorize the risks in the system as "definite," "possible," or "least" concern for commercial spaceflight. As with career astronauts, these risks will be primarily mitigated by screening and environmental control. Despite its focus on long-duration exploration missions, NASA's human system risk management approach can serve as a preliminary knowledge base to help medical planners prepare for commercial spaceflights. C1 [Vanderploeg, James M.; Kerstman, Eric L.] Univ Texas Med Branch, Galveston, TX 77555 USA. [Law, Jennifer] NASA, Lyndon B Johnson Space Ctr, Houston, TX 77058 USA. [Mathers, Charles H.] Mayo Clin, Div Prevent Occupat & Aerosp Med, Scottsdale, AZ USA. [Fondy, Susan R. E.] USA, Sch Aviat Med, Nas Pensacola, FL USA. RP Law, J (reprint author), NASA, Lyndon B Johnson Space Ctr, 2101 NASA Pkwy,Mail Code SD2, Houston, TX 77058 USA. EM jennifer.t.law@nasa.gov NR 11 TC 2 Z9 3 U1 0 U2 1 PU AEROSPACE MEDICAL ASSOC PI ALEXANDRIA PA 320 S HENRY ST, ALEXANDRIA, VA 22314-3579 USA SN 0095-6562 J9 AVIAT SPACE ENVIR MD JI Aviat. Space Environ. Med. PD JAN PY 2013 VL 84 IS 1 BP 68 EP 73 DI 10.3357/ASEM.3421.2013 PG 6 WC Public, Environmental & Occupational Health; Medicine, General & Internal; Sport Sciences SC Public, Environmental & Occupational Health; General & Internal Medicine; Sport Sciences GA 062LN UT WOS:000312921400013 PM 23305003 ER PT J AU Vergis, JM Cote, CK Bozue, J Alem, F Ventura, CL Welkos, SL O'Brien, AD AF Vergis, James M. Cote, Christopher K. Bozue, Joel Alem, Farhang Ventura, Christy L. Welkos, Susan L. O'Brien, Alison D. TI Immunization of Mice with Formalin-Inactivated Spores from Avirulent Bacillus cereus Strains Provides Significant Protection from Challenge with Bacillus anthracis Ames SO CLINICAL AND VACCINE IMMUNOLOGY LA English DT Article ID TOXIN GENES; IMMUNODOMINANT PROTEIN; SUBOPTIMAL AMOUNTS; UNITED-STATES; LETHAL FACTOR; MOUSE STRAIN; GUINEA-PIGS; VACCINE; ANTIGEN; EXOSPORIUM AB Bacillus anthracis spores are the infectious form of the organism for humans and animals. However, the approved human vaccine in the United States is derived from a vegetative culture filtrate of a toxigenic, nonencapsulated B. anthracis strain that primarily contains protective antigen (PA). Immunization of mice with purified spore proteins and formalin-inactivated spores (FIS) from a nonencapsulated, nontoxigenic B. anthracis strain confers protection against B. anthracis challenge when PA is also administered. To investigate the capacity of the spore particle to act as a vaccine without PA, we immunized mice subcutaneously with FIS from nontoxigenic, nonencapsulated B. cereus strain G9241 pBCXO1(-)/pBC210(-) (dcG9241), dcG9241 Delta bclA, or 569-UM20 or with exosporium isolated from dcG9241. FIS vaccination provided significant protection of mice from intraperitoneal or intranasal challenge with spores of the virulent B. anthracis Ames or Ames Delta bclA strain. Immunization with dcG9241 Delta bclA FIS, which are devoid of the immunodominant spore protein BclA, provided greater protection from challenge with either Ames strain than did immunization with FIS from BclA-producing strains. In addition, we used prechallenge immune antisera to probe a panel of recombinant B. anthracis Sterne spore proteins to identify novel immunogenic vaccine candidates. The antisera were variably reactive with BclA and with 10 other proteins, four of which were previously tested as vaccine candidates. Overall our data show that immunization with FIS from nontoxigenic, nonencapsulated B. cereus strains provides moderate to high levels of protection of mice from B. anthracis Ames challenge and that neither PA nor BclA is required for this protection. C1 [Vergis, James M.; Alem, Farhang; Ventura, Christy L.; O'Brien, Alison D.] Uniformed Serv Univ Hlth Sci, Dept Microbiol & Immunol, Bethesda, MD 20814 USA. [Cote, Christopher K.; Bozue, Joel; Welkos, Susan L.] USA, Med Res Inst Infect Dis, Bacteriol Div, Frederick, MD USA. RP O'Brien, AD (reprint author), Uniformed Serv Univ Hlth Sci, Dept Microbiol & Immunol, Bethesda, MD 20814 USA. EM alison.obrien@usuhs.edu OI O'Brien, Alison/0000-0002-1315-3204 FU Biological Defense Research Directorate, Naval Medical Research Center, U.S. Navy; JSTO-CBD/DTRA [1.1A0010-070RDB, CMB VAXBT-03-10-RDP 004] FX This work was funded by the Biological Defense Research Directorate, Naval Medical Research Center, U.S. Navy (to A.D.O.), and JSTO-CBD/DTRA projects 1.1A0010-070RDB and CMB VAXBT-03-10-RDP 004 (to S.L.W.). NR 67 TC 8 Z9 8 U1 1 U2 13 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA SN 1556-6811 EI 1556-679X J9 CLIN VACCINE IMMUNOL JI Clin. Vaccine Immunol. PD JAN PY 2013 VL 20 IS 1 BP 56 EP 65 DI 10.1128/CVI.00550-12 PG 10 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA 064HI UT WOS:000313064400009 PM 23114705 ER PT J AU Perez, LE Merrill, GA DeLorenzo, RA Schoenfeld, TW Vats, A Moser, MJ AF Perez, Luis E. Merrill, Gerald A. DeLorenzo, Robert A. Schoenfeld, Thomas W. Vats, Abhay Moser, Michael J. TI Evaluation of the specificity and sensitivity of a potential rapid influenza screening system SO DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE LA English DT Article DE Influenza A and B; PyroScript; RVP; Isothermal PCR ID RESPIRATORY-TRACT INFECTIONS; REVERSE TRANSCRIPTION-PCR; A VIRUS; MOLECULAR METHODS; VIRAL-INFECTIONS; GENE-EXPRESSION; DIAGNOSIS; PANEL; AMPLIFICATION; H1N1 AB Influenza remains a serious worldwide health threat with numerous deaths attributed to influenza-related complications. It is likely that transmission of influenza and both the morbidity and mortality of influenza could be reduced if inexpensive but reliable influenza screening assays were more available to the general public or local medical treatment facilities. This report provides the initial evaluation of a pilot system designed by Lucigen Corp. (Middleton, WI, USA) as a potential rapid near point-of-care screening system for influenza A and influenza B. The evaluation of specificity and sensitivity was conducted on stored nasal swab samples collected from emergency department patients presenting with influenza-like symptoms at a large military academic hospital and on de-identified nasal swabs and isolated RNA from a local epidemiology laboratory. The gold standard for assessment of specificity and sensitivity was the Luminex (R) Respiratory Viral Panel. Published by Elsevier Inc. C1 [Perez, Luis E.; Merrill, Gerald A.; DeLorenzo, Robert A.] Brooke Army Med Ctr, Dept Clin Invest, Ft Sam Houston, TX 78234 USA. [Schoenfeld, Thomas W.; Moser, Michael J.] Lucigen Corp, Middleton, WI 53562 USA. [Vats, Abhay] Univ Pittsburgh, Sch Med, Pittsburgh, PA 15224 USA. RP Perez, LE (reprint author), Brooke Army Med Ctr, Dept Clin Invest, Ft Sam Houston, TX 78234 USA. EM Luis.Perez2@amedd.army.mil FU Telemedicine and Advanced Technology Research Center (TATRC) [2007011131]; National Institute of Health [1 R43 AI081467-01A1]; Clinical Investigation, Brooke Army Medical Center [C.2009.128d] FX This research was supported by a Material Transfer Agreement to supply PyroScript influenza A and B reagents by Lucigen Corp., Telemedicine and Advanced Technology Research Center (TATRC) grant 2007011131 to R.A.D., National Institute of Health grant to T.S. and Dr. Abhay Vats (1 R43 AI081467-01A1), and Clinical Investigation, Brooke Army Medical Center grant C.2009.128d to L.E.P. NR 35 TC 2 Z9 3 U1 0 U2 11 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 0732-8893 J9 DIAGN MICR INFEC DIS JI Diagn. Microbiol. Infect. Dis. PD JAN PY 2013 VL 75 IS 1 BP 77 EP 80 DI 10.1016/j.diagmicrobio.2012.09.005 PG 4 WC Infectious Diseases; Microbiology SC Infectious Diseases; Microbiology GA 059CY UT WOS:000312683200016 PM 23083638 ER PT J AU Akbar, M Aliabadi, S Patel, R Watts, M AF Akbar, Muhammad Aliabadi, Shahrouz Patel, Reena Watts, Marvin TI A fully automated and integrated multi-scale forecasting scheme for emergency preparedness SO ENVIRONMENTAL MODELLING & SOFTWARE LA English DT Article DE Multi-scale hurricane simulation; Water surge; Overland flow; Finite element; Parallel computation; Fully automated through scripting ID DIFFUSION-WAVE TREATMENT; MODELS; INUNDATION; SYSTEM; FLOWS AB In this paper, we present one multi-scale integrated simulation technology for emergency preparedness with a holistic approach in hurricane, related storm surge and flood forecasting; infrastructure assessment; and emergency planning. This is an emergency management tool to aid the decision-makers and first responders in preparation for the appropriate response to an impending hurricane disaster. Three primary models, hurricane forecasting, storm surge, and overland flooding, are executed in sequence to generate the necessary results for the proposed integrated emergency planning and preparedness tool. Two of these are open source codes in the public domain and the overland flooding model is an "in-house" code developed by the authors. Using the results of the primary models, two secondary models are executed to assess local infrastructure vulnerability and to determine the optimal evacuation routes for impacted inhabitants. The results from each model are post-processed and saved as Keyhole Markup Language (KML) files that are viewable in Google Earth for overlay analysis and decision-making. Hurricane Katrina (2005) in the Mississippi coastal area is chosen as a case study to validate the developed tool. The models are run in sequence to generate the layers of data necessary during an actual event. The sequence is fully automated using Python and Shell scripts, which allow users to interact with each model through a series of Graphical User Interfaces. The development of technology described here would not only satisfy the scope of the project, but also be of great significance to national homeland security in the area of emergency preparedness and response. (C) 2012 Elsevier Ltd. All rights reserved. C1 [Akbar, Muhammad; Aliabadi, Shahrouz; Watts, Marvin] Jackson State Univ, Northrop Grumman Ctr High Performance Comp Ship S, MS E Ctr, Jackson, MS 39204 USA. [Patel, Reena] USA, Informat Technol Lab, Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. RP Akbar, M (reprint author), Jackson State Univ, Northrop Grumman Ctr High Performance Comp Ship S, MS E Ctr, Box 1400,1230 Raymond Rd, Jackson, MS 39204 USA. EM muhammad.k.akbar@jsums.edu; saliabadi@jsums.edu; reena.r.patel@usace.army.mil; marvin.d.watts@jsums.edu FU U.S. Department of Homeland Security (DHS) through the South East Regional Research Initiative (SERRI); DHS FX This work is sponsored by the U.S. Department of Homeland Security (DHS) through the South East Regional Research Initiative (SERRI). Authors would like to thank DHS for their support. NR 57 TC 12 Z9 12 U1 2 U2 35 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 1364-8152 J9 ENVIRON MODELL SOFTW JI Environ. Modell. Softw. PD JAN PY 2013 VL 39 SI SI BP 24 EP 38 DI 10.1016/j.envsoft.2011.12.006 PG 15 WC Computer Science, Interdisciplinary Applications; Engineering, Environmental; Environmental Sciences SC Computer Science; Engineering; Environmental Sciences & Ecology GA 056UP UT WOS:000312517200003 ER PT J AU George, J AF George, Jemin TI Robust Kalman-Bucy Filter SO IEEE TRANSACTIONS ON AUTOMATIC CONTROL LA English DT Article DE H-infinity filtering; Kalman-Bucy filter ID UNCERTAIN LINEAR-SYSTEMS; DISCRETE-TIME-SYSTEMS; STATE ESTIMATION; H-INFINITY; PARAMETERS; CONSTRAINT; DESIGN; MODELS AB Development of a robust estimator for uncertain stochastic systems under persistent excitation is presented. The given continuous-time stochastic formulation assumes norm bounded parametric uncertainties and excitations. When there are no system uncertainties, the performance of the proposed robust estimator is similar to that of the Kalman-Bucy filter and the proposed approach asymptotically recovers the desired optimal performance in the presence of uncertainties and or persistent excitation. C1 USA, Res Lab, Adelphi, MD 20783 USA. RP George, J (reprint author), USA, Res Lab, Adelphi, MD 20783 USA. EM jemin.george.civ@mail.mil NR 32 TC 10 Z9 12 U1 4 U2 31 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI PISCATAWAY PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA SN 0018-9286 J9 IEEE T AUTOMAT CONTR JI IEEE Trans. Autom. Control PD JAN PY 2013 VL 58 IS 1 BP 174 EP 180 DI 10.1109/TAC.2012.2203052 PG 8 WC Automation & Control Systems; Engineering, Electrical & Electronic SC Automation & Control Systems; Engineering GA 062DC UT WOS:000312898300015 ER PT J AU Morris, GR Abed, KH AF Morris, Gerald R. Abed, Khalid H. TI Mapping a Jacobi Iterative Solver onto a High-Performance Heterogeneous Computer SO IEEE TRANSACTIONS ON PARALLEL AND DISTRIBUTED SYSTEMS LA English DT Article DE Field programmable gate array (FPGA); reconfigurable computer (RC); high-performance reconfigurable computer (HPRC); high-performance heterogeneous computer (HPHC); Jacobi iterative method ID MOLECULAR-DYNAMICS; LINEAR-SYSTEMS; REDUCTION; MATRICES; IMPLEMENTATION; CONVERGENCE; FPGAS AB High-performance heterogeneous computers that employ field programmable gate arrays (FPGAs) as computational elements are known as high-performance reconfigurable computers (HPRCs). For floating-point applications, these FPGA-based processors must satisfy a variety of heuristics and rules of thumb to achieve a speedup compared with their software counterparts. By way of a simple sparse matrix Jacobi iterative solver, this paper illustrates some of the issues associated with mapping floating-point kernels onto HPRCs. The Jacobi method was chosen based on heuristics developed from earlier research. Furthermore, Jacobi is relatively easy to understand, yet is complex enough to illustrate the mapping issues. This paper is not trying to demonstrate the speedup of a particular application nor is it suggesting that Jacobi is the best way to solve equations. The results demonstrate a nearly threefold wall clock runtime speedup when compared with a software implementation. A formal analysis shows that these results are reasonable. The purpose of this paper is to illuminate the challenging floating-point mapping process while simultaneously showing that such mappings can result in significant speedups. The ideas revealed by research such as this have already been and should continue to be used to facilitate a more automated mapping process. C1 [Morris, Gerald R.] USA, Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. [Abed, Khalid H.] Jackson State Univ, Dept Comp Engn, Jackson, MS 39217 USA. RP Morris, GR (reprint author), USA, Engineer Res & Dev Ctr, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA. EM gerald.r.morris@us.army.mil; khalid.h.abed@jsums.edu OI Abed, Khalid/0000-0002-5203-2907 FU DoD High Performance Computing Modernization Program [W912HZ-(08-C-0073), W912HZ-(09-C-0108), W912HZ-(10-C-0107)]; Army Research Office HBCU/MSI [W911NF-07-1-0527]; US Army Engineer Research and Development Center FX This work was supported in part by the DoD High Performance Computing Modernization Program under contract numbers W912HZ-(08-C-0073, 09-C-0108, and 10-C-0107), "High Performance Computational Design of Novel Materials," in part by Army Research Office HBCU/MSI grant number W911NF-07-1-0527, and in part by the US Army Engineer Research and Development Center. NR 51 TC 7 Z9 7 U1 1 U2 12 PU IEEE COMPUTER SOC PI LOS ALAMITOS PA 10662 LOS VAQUEROS CIRCLE, PO BOX 3014, LOS ALAMITOS, CA 90720-1314 USA SN 1045-9219 EI 1558-2183 J9 IEEE T PARALL DISTR JI IEEE Trans. Parallel Distrib. Syst. PD JAN PY 2013 VL 24 IS 1 BP 85 EP 91 DI 10.1109/TPDS.2012.121 PG 7 WC Computer Science, Theory & Methods; Engineering, Electrical & Electronic SC Computer Science; Engineering GA 061GV UT WOS:000312837400008 ER PT J AU Langer, T Vecchi, V Belenkiy, SM Cancio, LC Gattinoni, L Batchinsky, AI AF Langer, Thomas Vecchi, Vittoria Belenkiy, Slava M. Cancio, Leopoldo C. Gattinoni, Luciano Batchinsky, Andriy I. TI Pressure-guided positioning of bicaval dual-lumen catheters for venovenous extracorporeal gas exchange SO INTENSIVE CARE MEDICINE LA English DT Article DE Extracorporeal membrane oxygenation; Catheterization; Acute respiratory distress syndrome ID MEMBRANE-OXYGENATION; TRANSTHORACIC ECHOCARDIOGRAPHY; LUNG TRANSPLANTATION; ARTIFICIAL LUNG; LIFE-SUPPORT; RECIRCULATION; INSERTION; CANNULA AB Purpose: Bicaval dual-lumen catheters allow for single-site cannulation venovenous extracorporeal gas exchange and facilitate early mobilization of patients. Using these catheters blood is drained from the superior and inferior venae cavae, pumped through a respiratory membrane, and returned into the right atrium. The insertion of these catheters is challenging as their correct positioning is fundamental to reduce recirculation and avoid severe complications. We describe here a new technique for the positioning of bicaval dual-lumen catheters. Materials and methods: The right internal jugular vein was percutaneously cannulated in nine sheep. The distance between skin and tricuspid valve was measured from the point of pressure change in the waveform of a Swan-Ganz catheter being retracted from the right ventricle into the right atrium. The atrium-tricuspid valve-ventricle axis was determined by observing the fluctuations of the tip of the Swan-Ganz entering the ventricle during fluoroscopy. A bicaval dual-lumen catheter was placed on the basis of these evaluations and connected to an extracorporeal respiratory support system. Results: The position of the catheter was verified at necropsy approximately 18 h after insertion. In all cases the catheter was correctly placed, with the central port situated in front of the tricuspid valve. Conclusions: The described technique may help to position bicaval dual-lumen catheters for venovenous extracorporeal gas exchange without the use of transesophageal echocardiography or contrast media during fluoroscopy. C1 [Langer, Thomas; Vecchi, Vittoria; Belenkiy, Slava M.; Cancio, Leopoldo C.; Batchinsky, Andriy I.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Langer, Thomas; Gattinoni, Luciano] Univ Milan, Dipartimento Fisiopatol Med Chirurg & Trapianti, Milan, Italy. [Vecchi, Vittoria] Univ Milan, Sch Med, Milan, Italy. [Langer, Thomas; Vecchi, Vittoria] Natl Acad, Natl Res Council, Washington, DC USA. RP Langer, T (reprint author), USA, Inst Surg Res, 3400 Rawley E Chamber Ave, Ft Sam Houston, TX 78234 USA. EM thomas.langer@unimi.it FU US Army Combat Casualty Care Research Program FX We are grateful to Mr. Glen Gueller for assistance with the illustrations used in this manuscript. This study was supported in part by the US Army Combat Casualty Care Research Program. NR 15 TC 9 Z9 9 U1 0 U2 3 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 0342-4642 J9 INTENS CARE MED JI Intensive Care Med. PD JAN PY 2013 VL 39 IS 1 BP 151 EP 154 DI 10.1007/s00134-012-2751-5 PG 4 WC Critical Care Medicine SC General & Internal Medicine GA 052JK UT WOS:000312193700021 PM 23160771 ER PT J AU Hilton, CD McCauley, JW Swab, JJ Shanholtz, ER Chen, MW AF Hilton, Corydon D. McCauley, James W. Swab, Jeffrey J. Shanholtz, Eugene R. Chen, Ming W. TI Using Hardness Tests to Quantify Bulk Plasticity and Predict Transition Velocities in SiC Materials SO INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY LA English DT Article ID INDENTATION; CERAMICS; SIZE; PENETRATION; ARMOR AB It has long been known that a relation exists between a material's hardness and its gross impact performance; however, the nature of this relationship has not been understood to a degree useful in materials development. Many studies have shown that harder ceramics tend to display better ballistic performance. In addition, some research has suggested that a material's potential for inelastic deformation (or its quasi-plasticity a bulk property) may also play an important role in its resistance to penetration. Methods of quantifying the bulk plasticity of a ceramic material are, however, extremely limited. The current study continues an investigation into a recently proposed technique to (1) quantify bulk quasi-plasticity in SiC materials, and (2) use the plasticity value along with a hardness value to predict the transition velocity of potential armor ceramics. The transition velocity values predicted by this approach generally show excellent agreement (within 5% in most cases) with experimentally determined velocities. In addition, the robustness of this predictive technique is demonstrated through the use of multiple operators and multiple hardness testing units. C1 [Hilton, Corydon D.; McCauley, James W.; Swab, Jeffrey J.; Shanholtz, Eugene R.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA. [Chen, Ming W.] Tohoku Univ, WPI Adv Inst Mat Res, Sendai, Miyagi 9808577, Japan. [Chen, Ming W.] JST, CREST, Kawaguchi, Saitama 3320012, Japan. [Chen, Ming W.] Shanghai Jiao Tong Univ, Sch Mat Sci & Engn, State Key Lab Met Matrix Composites, Shanghai 200030, Peoples R China. RP Hilton, CD (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA. EM corydon.d.hilton.ctr@mail.mil RI Chen, Mingwei/A-4855-2010 OI Chen, Mingwei/0000-0002-2850-8872 NR 28 TC 2 Z9 2 U1 1 U2 26 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 1546-542X J9 INT J APPL CERAM TEC JI Int. J. Appl. Ceram. Technol. PD JAN-FEB PY 2013 VL 10 IS 1 BP 114 EP 122 DI 10.1111/j.1744-7402.2012.02817.x PG 9 WC Materials Science, Ceramics SC Materials Science GA 063JC UT WOS:000312992100015 ER PT J AU Russell, K Shen, Q AF Russell, Kevin Shen, Qiong TI Expanded spatial four-link motion and path generation with order and branch defect elimination SO INVERSE PROBLEMS IN SCIENCE AND ENGINEERING LA English DT Article DE motion generation; path generation; RRSS linkage; 4R spherical linkage; optimization ID KINEMATIC SYNTHESIS; RRSS MECHANISMS AB This work addresses the inverse problems of expanded motion and path generation for the spatial (revoluterevolutesphericalspherical, RRSS) linkage and the 4R spherical linkage with order and branch elimination. Two constrained non-linear equation systems are presented in this work for RRSS and 4R spherical motion and path generation with order and branching constraints. Both equation systems include the spatial four-link displacement model (by Suh and Radcliffe) as an objective function along with order and branching inequality constraints. As examples, both a branch defect-free and order defect-free RRSS linkage 4R spherical linkage are synthesized to approximate expanded groups of precision positions. C1 [Russell, Kevin] USA, Res Dev & Engn Ctr, Armaments Engn & Technol Ctr, Picatinny Arsenal, NJ 07806 USA. [Shen, Qiong] Emerson Network Power, Power Control Syst Engn, Florham Pk, NJ 07932 USA. RP Russell, K (reprint author), USA, Res Dev & Engn Ctr, Armaments Engn & Technol Ctr, Picatinny Arsenal, NJ 07806 USA. EM kevin.russell1@us.army.mil RI Shen, Qiong/N-4015-2013 NR 15 TC 4 Z9 4 U1 0 U2 1 PU TAYLOR & FRANCIS LTD PI ABINGDON PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND SN 1741-5977 J9 INVERSE PROBL SCI EN JI Inverse Probl. Sci. Eng. PD JAN 1 PY 2013 VL 21 IS 1 BP 129 EP 140 DI 10.1080/17415977.2012.672418 PG 12 WC Engineering, Multidisciplinary; Mathematics, Interdisciplinary Applications SC Engineering; Mathematics GA 063XU UT WOS:000313036200008 ER PT J AU Sanborn, B Nie, X Chen, W Weerasooriya, T AF Sanborn, B. Nie, X. Chen, W. Weerasooriya, T. TI High Strain Rate Pure Shear and Axial Compressive Response of Porcine Lung Tissue SO JOURNAL OF APPLIED MECHANICS-TRANSACTIONS OF THE ASME LA English DT Article ID MECHANICAL-PROPERTIES; BAR; PARENCHYMA AB In this study, both the dynamic shear (torsion) and axial compressive responses of porcine lung tissue were examined using modified Kolsky bar techniques. High-rate compression data were collected using a Kolsky bar with a hollow transmission bar on annular specimens at strain rates between 1000-3000 s(-1). The radial deformation of the annular specimen was recorded on a modified single loading Kolsky bar using highspeed imaging capabilities. The collected images and analysis of boundary movement indicated inhomogeneous specimen deformation induced by radial inertia, which significantly altered the desired uniaxial stress state in such high-rate compression test techniques. A novel torsion experimental technique was developed to obtain the dynamic pure shear behavior of lung tissue at shear strain rates above 500 s(-1) without inertia effects. The pure shear response was found to be two orders of magnitude weaker than the uniaxial compressive response when compared by equivalent stress-strain relations. [DOI: 10.1115/1.4007222] C1 [Sanborn, B.; Weerasooriya, T.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA. [Nie, X.; Chen, W.] Purdue Univ, Sch Aeronaut Astronaut, W Lafayette, IN 47907 USA. [Nie, X.; Chen, W.] Purdue Univ, Sch Mat Engn, W Lafayette, IN 47907 USA. RP Sanborn, B (reprint author), USA, Res Lab, Bldg 4600, Aberdeen Proving Ground, MD 21005 USA. EM brett.sanborn2.ctr@mail.mil FU US Army Research Laboratory; Purdue University FX This research is supported by a collaborative program between US Army Research Laboratory and Purdue University. NR 17 TC 0 Z9 0 U1 0 U2 11 PU ASME-AMER SOC MECHANICAL ENG PI NEW YORK PA THREE PARK AVE, NEW YORK, NY 10016-5990 USA SN 0021-8936 J9 J APPL MECH-T ASME JI J. Appl. Mech.-Trans. ASME PD JAN PY 2013 VL 80 IS 1 AR 011029 DI 10.1115/1.4007222 PG 6 WC Mechanics SC Mechanics GA 063VF UT WOS:000313029400029 ER PT J AU Morton, TN Zimmerman, JP Lee, M Schaber, JD AF Morton, Troy N. Zimmerman, Jeffrey P. Lee, Michael Schaber, John D. TI A Review of 105 Consecutive Uniport Endoscopic Plantar Fascial Release Procedures for the Treatment of Chronic Plantar Fasciitis SO JOURNAL OF FOOT & ANKLE SURGERY LA English DT Review DE calcaneus; chronic inflammation; endoscopy; heel pain; plantar fasciitis; surgery ID TRIAL AB Plantar fasciitis is a common cause of heel pain in the U. S. Army soldier, resulting in a significant loss of man hours. Given the heavy operations tempo of the U. S. military, successful treatment options need to be considered and used as quickly as possible. Plantar fasciitis can be successfully treated in up to 90% of patients using conservative measures. Operative intervention might need to be considered for those in whom conservative measures have failed. The present report is a review of 105 consecutive uniport endoscopic plantar fascial release procedures performed by the principal investigator during a 9-year period. The following data were collected and analyzed: gender, age, weight, height, body mass index, medical treatment facility, procedure laterality, preoperative pain levels, postoperative pain levels at 3 months, first ambulatory day in the controlled ankle motion boot, return to activity as tolerated, and complications. Three major points were of interest: evidence of improvement in chronic plantar fasciitis when treated with uniport endoscopic procedures; the patient attributes associated with self-reported pain levels 90 days postoperatively; and the patient attributes associated with the average time until patients were able to return to activities as tolerated in a controlled ankle motion boot. It was noted that 44.5% of those with a body mass index of 29.80 kg/m(2) or greater reported a postoperative pain level of 0; and 96.3% of those with a body mass index of 25.53 kg/m(2) or less reported postoperative pain levels of 0. The analyzed data were used to characterize the clinical outcomes of the procedure, identify changes in outcome with surgeon experience, and identify whether certain patient subgroups have better outcomes, allowing surgeons to identify which patient might be the best candidates for an endoscopic release procedure. (C) 2013 by the American College of Foot and Ankle Surgeons. All rights reserved. C1 [Morton, Troy N.] Reynolds Army Community Hosp, Dept Surg, Ft Sill, OK 73503 USA. [Zimmerman, Jeffrey P.] Womack Army Med Ctr, Ft Bragg, NC USA. [Schaber, John D.] William Beaumont Army Med Ctr, Dept Pathol, El Paso, TX 79920 USA. RP Morton, TN (reprint author), Reynolds Army Community Hosp, Dept Surg, 4301 Wilson St, Ft Sill, OK 73503 USA. EM Troy.Morton@us.army.mil NR 12 TC 5 Z9 5 U1 1 U2 10 PU ELSEVIER SCIENCE INC PI NEW YORK PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN 1067-2516 J9 J FOOT ANKLE SURG JI J. Foot Ankle Surg. PD JAN-FEB PY 2013 VL 52 IS 1 BP 48 EP 52 DI 10.1053/j.jfas.2012.10.011 PG 5 WC Orthopedics; Surgery SC Orthopedics; Surgery GA 061ZU UT WOS:000312889700011 PM 23177328 ER PT J AU Grujicic, M Pandurangan, B Arakere, A Yen, CF Cheeseman, BA AF Grujicic, M. Pandurangan, B. Arakere, A. Yen, C-F. Cheeseman, B. A. TI Friction Stir Weld Failure Mechanisms in Aluminum-Armor Structures Under Ballistic Impact Loading Conditions SO JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE LA English DT Article DE aluminum armor; ballistic limit; failure mechanisms; friction stir welding ID NOSE STEEL PROJECTILES; 6061-T6 ALUMINUM; PLATES; PERFORATION; MICROSTRUCTURE; EVOLUTION; ALLOYS; AA5083 AB A critical assessment is carried out of the microstructural changes in respect of the associated reductions in material mechanical properties and of the attendant ballistic-impact failure mechanisms in prototypical friction stir welding (FSW) joints found in armor structures made of high-performance aluminum alloys (including solution-strengthened and age-hardenable aluminum alloy grades). It is argued that due to the large width of FSW joints found in thick aluminum-armor weldments, the overall ballistic performance of the armor is controlled by the ballistic limits of its weld zones (e.g., heat-affected zone, the thermomechanically affected zone, the nugget, etc.). Thus, in order to assess the overall ballistic survivability of an armor weldment, one must predict/identify welding-induced changes in the material microstructure and properties, and the operative failure mechanisms in different regions of the weld. Toward this end, a procedure is proposed in the present study which combines the results of the FSW process modeling, basic physical-metallurgy principles concerning microstructure/property relations, and the fracture mechanics concepts related to the key blast/ballistic-impact failure modes. The utility of this procedure is demonstrated using the case of a solid-solution strengthened and cold-worked aluminum alloy armor FSW-weld test structure. C1 [Grujicic, M.; Pandurangan, B.; Arakere, A.] Clemson Univ, Dept Mech Engn, Clemson, SC 29634 USA. [Yen, C-F.; Cheeseman, B. A.] USA, Res Lab, Survivabil Mat Branch, Aberdeen Proving Ground, MD 21005 USA. RP Grujicic, M (reprint author), Clemson Univ, Dept Mech Engn, 241 Engn Innovat Bldg, Clemson, SC 29634 USA. EM gmica@clemson.edu FU Army Research Office [W911NF-11-1-0207, W911NF-09-1-0513]; U.S. Army/Clemson University [W911NF-04-2-0024, W911NF-06-2-0042] FX The material presented in this article is based on the study supported by two Army Research Office sponsored grants (W911NF-11-1-0207 and W911NF-09-1-0513) and two U.S. Army/Clemson University Cooperative Agreements (W911NF-04-2-0024 and W911NF-06-2-0042). NR 42 TC 8 Z9 8 U1 0 U2 22 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1059-9495 J9 J MATER ENG PERFORM JI J. Mater. Eng. Perform. PD JAN PY 2013 VL 22 IS 1 BP 30 EP 40 DI 10.1007/s11665-012-0239-7 PG 11 WC Materials Science, Multidisciplinary SC Materials Science GA 059NT UT WOS:000312712900004 ER PT J AU Apland, JP Aroniadou-Anderjaska, V Figueiredo, TH Green, CE Swezey, R Yang, C Qashu, F Braga, MFM AF Apland, James P. Aroniadou-Anderjaska, Vassiliki Figueiredo, Taiza H. Green, Carol E. Swezey, Robert Yang, Chun Qashu, Felicia Braga, Maria F. M. TI Efficacy of the GluK1/AMPA Receptor Antagonist LY293558 against Seizures and Neuropathology in a Soman-Exposure Model without Pretreatment and its Pharmacokinetics after Intramuscular Administration SO JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS LA English DT Article ID ORGANOPHOSPHORUS NERVE AGENTS; AMYGDALA; EPILEPTOGENESIS; DEFICITS; RATS AB Control of brain seizures after exposure to nerve agents is imperative for the prevention of brain damage and death. Animal models of nerve agent exposure make use of pretreatments, or medication administered within 1minute after exposure, in order to prevent rapid death from peripheral toxic effects and respiratory failure, which then allows the testing of anticonvulsant compounds. However, in a real-case scenario of an unexpected attack with nerve agents, pretreatment would not be possible, and medical assistance may not be available immediately. To determine if control of seizures and survival are still possible without pretreatment or immediate pharmacologic intervention, we studied the anticonvulsant efficacy of the GluK1 (GluR5)/alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist (3S,4aR,6R,8aR)-6-[2-(1(2)H-tetrazole-5-yl)ethyl]decahydroisoquinoline-3-carboxylic acid (LY293558) in rats that did not receive any treatment until 20 minutes after exposure to the nerve agent soman. We injected LY293558 intramuscularly, as this would be the most likely route of administration to humans. LY293558 (15 mg/kg), injected along with atropine and the oxime HI-6 at 20 minutes after soman exposure, stopped seizures and increased survival rate from 64% to 100%. LY293558 also prevented neuronal loss in the amygdala and hippocampus, and reduced neurodegeneration in a number of brain regions studied 7 days after soman exposure. Analysis of the LY293558 pharmacokinetics after intramuscular administration showed that this compound readily crosses the blood-brain barrier. There was good correspondence between the time course of seizure suppression by LY293558 and the brain levels of the compound. C1 [Aroniadou-Anderjaska, Vassiliki; Figueiredo, Taiza H.; Qashu, Felicia; Braga, Maria F. M.] Uniformed Serv Univ Hlth Sci, F Edward Hebert Sch Med, Dept Anat Physiol & Genet, Bethesda, MD 20814 USA. [Aroniadou-Anderjaska, Vassiliki; Braga, Maria F. M.] Uniformed Serv Univ Hlth Sci, F Edward Hebert Sch Med, Dept Psychiat, Bethesda, MD 20814 USA. [Apland, James P.] USA, Med Res Inst Chem Def, Neurobehav Toxicol Branch, Aberdeen Proving Ground, MD 21010 USA. [Green, Carol E.; Swezey, Robert; Yang, Chun] SRI Int, Biosci Div, Menlo Pk, CA 94025 USA. RP Braga, MFM (reprint author), Uniformed Serv Univ Hlth Sci, F Edward Hebert Sch Med, Dept Anat Physiol & Genet, 4301 Jones Bridge Rd, Bethesda, MD 20814 USA. EM maria.braga@usuhs.edu FU CounterACT Program, National Institutes of Health, Office of the Director; National Institutes of Health National Institute of Neurological Disorders and Stroke [5U01NS058162-07]; Defense Threat Reduction Agency-Joint Science and Technology Office, Medical ST Division [CBM.NEURO.01.10.US.18, CBM.NEURO.01.10.US.15] FX This work was supported by the CounterACT Program, National Institutes of Health, Office of the Director; and the National Institutes of Health National Institute of Neurological Disorders and Stroke [Grant 5U01NS058162-07], and the Defense Threat Reduction Agency-Joint Science and Technology Office, Medical S&T Division [Grant CBM.NEURO.01.10.US.18 and CBM.NEURO.01.10.US.15]. NR 30 TC 6 Z9 7 U1 0 U2 11 PU AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3995 USA SN 0022-3565 J9 J PHARMACOL EXP THER JI J. Pharmacol. Exp. Ther. PD JAN PY 2013 VL 344 IS 1 BP 133 EP 140 DI 10.1124/jpet.112.198689 PG 8 WC Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA 060VE UT WOS:000312805500016 PM 23042954 ER PT J AU Keyser, BM Andres, DK Nealley, E Holmes, WW Benton, B Paradiso, D Appell, A Carpin, C Anderson, DR Smith, WJ Ray, R AF Keyser, Brian M. Andres, Devon K. Nealley, Eric Holmes, Wesley W. Benton, Betty Paradiso, Danielle Appell, Ashley Carpin, Chris Anderson, Dana R. Smith, William J. Ray, Radharaman TI Postexposure Application of Fas Receptor Small-Interfering RNA to Suppress Sulfur Mustard-Induced Apoptosis in Human Airway Epithelial Cells: Implication for a Therapeutic Approach SO JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS LA English DT Article ID ACUTE LUNG INJURY; PULMONARY APOPTOSIS; CHEMICAL WARFARE; DELIVERY; EXPOSURE; PATHWAY; LIGAND; SIRNA; FLUID; KERATINOCYTES AB Sulfur mustard (SM) is a vesicant chemical warfare and terrorism agent. Besides skin and eye injury, respiratory damage has been mainly responsible for morbidity and mortality after SM exposure. Previously, it was shown that suppressing the death receptor (DR) response by the dominant-negative Fas-associated death domain protein prior to SM exposure blocked apoptosis and microvesication in skin. Here, we studied whether antagonizing the Fas receptor (FasR) pathway by small-interfering RNA (siRNA) applied after SM exposure would prevent apoptosis and, thus, airway injury. Normal human bronchial/tracheal epithelial (NHBE) cells were used as an in vitro model with FasR siRNA, FasR agonistic antibody CH11, and FasR antagonistic antibody ZB4 as investigative tools. In NHBE cells, both SM (300 mu M) and CH11 (100 ng/ml) induced caspase-3 activation, which was inhibited by FasR siRNA and ZB4, indicating that SM-induced apoptosis was via the Fas response. FasR siRNA inhibited SM-induced caspase-3 activation when added to NHBE cultures up to 8 hours after SM. Results using annexin V/propidium iodide-stained cells showed that both apoptosis and necrosis were involved in cell death due to SM; FasR siRNA decreased both apoptotic and necrotic cell populations. Bronchoalveolar lavage fluid (BALF) of rats exposed to SM (1 mg/kg, 50 minutes) revealed a significant (P < 0.05) increase in soluble Fas ligand and active caspase-3 in BALF cells. These findings suggest an intervention of Fas-mediated apoptosis as a postexposure therapeutic strategy with a therapeutic window for SM inhalation injury and possibly other respiratory diseases involving the Fas response. C1 [Ray, Radharaman] USA, Med Res Inst Chem Def, Div Res, Cellular & Mol Biol Branch, Aberdeen Proving Ground, MD 21010 USA. [Holmes, Wesley W.; Paradiso, Danielle; Anderson, Dana R.] USA, Med Res Inst Chem Def, Med Toxicol Branch, Aberdeen Proving Ground, MD 21010 USA. RP Ray, R (reprint author), USA, Med Res Inst Chem Def, Div Res, Cellular & Mol Biol Branch, 3100 Ricketts Point Rd, Aberdeen Proving Ground, MD 21010 USA. EM radharaman.ray@us.army.mil OI Andres, Devon/0000-0002-6823-4132 FU Defense Threat Reduction Agency-Joint Science and Technology Office, Medical ST Division [CBM.RESP.01.10.RC.015, 3.F0011-08-RC-C] FX This work was supported by the Defense Threat Reduction Agency-Joint Science and Technology Office, Medical S&T Division [Grants CBM.RESP.01.10.RC.015, 3.F0011-08-RC-C]. Additionally, this research was supported in part by an appointment to the Postgraduate Research Participation Program at the U.S. Army Medical Research Institute of Chemical Defense administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the U.S. Department of Energy and U.S. Army Medical Research and Materiel Command (USAMRMC). B. M. K., W. W. H., D. R. A., and R. R. acquired funding for the research. NR 42 TC 6 Z9 9 U1 0 U2 16 PU AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3995 USA SN 0022-3565 J9 J PHARMACOL EXP THER JI J. Pharmacol. Exp. Ther. PD JAN PY 2013 VL 344 IS 1 BP 308 EP 316 DI 10.1124/jpet.112.199935 PG 9 WC Pharmacology & Pharmacy SC Pharmacology & Pharmacy GA 060VE UT WOS:000312805500032 PM 23129783 ER PT J AU Sellers, MCK Castle, BM Marsh, CP AF Sellers, Meredith C. K. Castle, Benjamin M. Marsh, Charles P. TI Three-dimensional manganese dioxide-functionalized carbon nanotube electrodes for electrochemical supercapacitors SO JOURNAL OF SOLID STATE ELECTROCHEMISTRY LA English DT Article DE Electrochemical capacitor; Carbon nanotube; Manganese dioxide; Pseudocapacitance ID RAMAN-SPECTROSCOPY; MNO2 NANOWIRES; COMPOSITES; GRAPHENE; STORAGE; SURFACE; SHEETS; XPS AB Three-dimensional manganese dioxide (MnO2)-functionalized multiwalled carbon nanotube (MWCNT) electrodes have been produced by a simple and scalable thermal decomposition process. The electrodes are prepared by treating planar MWCNT sheets with manganese(II) nitrate (Mn(NO3)(2)) solution and annealing at low temperature (200-300 A degrees C) and ambient pressure. The morphology, chemical composition, and structure of the resulting matrices have been investigated with scanning electron microscopy, X-ray photoelectron spectroscopy, Raman spectroscopy, and X-ray diffraction. Supercapacitors assembled with three-dimensional electrodes exhibit a 14-fold increase in specific capacitance (C (sp)) in comparison to those containing pristine, two-dimensional MWCNT electrodes. C (sp) varies linearly with Mn(NO3)(2) thermal decomposition temperature (from 100 to 61 F/g at 0.2 A/g), a trend that is discussed in the context of nitrate reaction chemistry and MWCNT structure. This efficient and promising approach allows for simultaneous enhancement of electrode-electrolyte contact area and incorporation of redox-based charge storage within electrochemical capacitors. C1 [Sellers, Meredith C. K.; Castle, Benjamin M.; Marsh, Charles P.] USA, Construct Engn Res Lab, Engineer Res & Dev Ctr, Champaign, IL 61822 USA. [Marsh, Charles P.] Univ Illinois, Dept Nucl Plasma & Radiol Engn, Urbana, IL 61801 USA. RP Sellers, MCK (reprint author), USA, Construct Engn Res Lab, Engineer Res & Dev Ctr, 2902 Newmark Dr, Champaign, IL 61822 USA. EM mcksellers@gmail.com FU US Army Corps of Engineers, Engineer Research and Development Center, Section 219 Center Directed Research program; US Department of Energy [DE-FG02-07ER46453, DE-FG02-07ER46471]; National Science Foundation FX This research was funded by the US Army Corps of Engineers, Engineer Research and Development Center, Section 219 Center Directed Research program. Dr. Sellers is supported by a postdoctoral fellowship administered by the Oak Ridge Institute for Science and Education (ORISE). Materials characterization was performed at the Center for Microanalysis of Materials at the Frederick Seitz Materials Research Laboratory, University of Illinois, which is partially supported by the US Department of Energy (DE-FG02-07ER46453 and DE-FG02-07ER46471) and by the National Science Foundation. We are grateful for the assistance of Dr. Rick Haasch, Niels Zussblatt, Dr. Julio Soares, and Robert Weber. NR 37 TC 5 Z9 5 U1 4 U2 71 PU SPRINGER PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 USA SN 1432-8488 J9 J SOLID STATE ELECTR JI J. Solid State Electrochem. PD JAN PY 2013 VL 17 IS 1 BP 175 EP 182 DI 10.1007/s10008-012-1863-8 PG 8 WC Electrochemistry SC Electrochemistry GA 064BO UT WOS:000313046100019 ER PT J AU Benson, M Laskowski, G Elkins, C Eaton, JK AF Benson, Michael Laskowski, Gregory Elkins, Chris Eaton, John K. TI Film-Cooled Trailing Edge Measurements: 3D Velocity and Scalar Field SO JOURNAL OF TURBOMACHINERY-TRANSACTIONS OF THE ASME LA English DT Article ID MAGNETIC-RESONANCE VELOCIMETRY; GAS-TURBINE AIRFOILS; COOLING EFFECTIVENESS; CUTBACK AB Aircraft turbine blade trailing edges commonly are cooled by blowing air through pressure-side cutback slots. The surface effectiveness is governed by the rate of mixing of the coolant with the mainstream, which is typically much faster than predicted by CFD models. Three-dimensional velocity and coolant concentration fields were measured in and around a cutback slot using a simple uncambered airfoil with a realistic trailing edge cooling geometry at a Reynolds number of 110,000 based on airfoil chord length, which is lower than practical engines but still in the turbulent regime. The results were obtained using magnetic resonance imaging (MRI) techniques in a water flow apparatus. Magnetic resonance concentration (MRC) scans measured the concentration distribution with a spatial resolution of 0.5 mm(3) (compared to a slot height of 5 mm) and an uncertainty near 5%. Magnetic resonance velocimetry (MRV) was used to acquire 3D, three-component mean velocity measurements with a resolution of 1.0 mm(3). Coupled concentration and velocity measurements were used to identify flow structures contributing to the rapid mixing, including longitudinal vortices and separation bubbles. Velocity measurements at several locations were compared with an unsteady RANS model. Concentration measurements extrapolated to the surface provided film cooling effectiveness and showed that the longitudinal vortices decreased effectiveness near the lands and reduced the average film cooling effectiveness. [DOI: 10.1115/1.4006425] C1 [Benson, Michael] US Mil Acad, West Point, NY 10996 USA. [Laskowski, Gregory] GE Global Res Ctr, Niskayuna, NY 12309 USA. [Elkins, Chris; Eaton, John K.] Stanford Univ, Stanford, CA 94305 USA. RP Benson, M (reprint author), US Mil Acad, West Point, NY 10996 USA. EM michael.benson@usma.edu; laskowsk@ge.com; celkins@stanford.edu; eatonj@stanford.edu FU United States Army Research Office; General Electric University; Stanford Department of Radiology FX This work was funded both by the United States Army Research Office and the General Electric University Strategic Alliance program. The authors would like to thank Mr. Cory Williams at GEAE for providing support for this work. Use of the facilities at the Richard M. Lucas Center for Magnetic Resonance Spectroscopy and Imaging is gratefully acknowledged along with funded scan time from the Stanford Department of Radiology. The views expressed herein are those of the authors and do not purport to reflect the position of the Department of the Army, or the Department of Defense. NR 20 TC 0 Z9 0 U1 1 U2 11 PU ASME-AMER SOC MECHANICAL ENG PI NEW YORK PA THREE PARK AVE, NEW YORK, NY 10016-5990 USA SN 0889-504X J9 J TURBOMACH JI J. Turbomach.-Trans. ASME PD JAN PY 2013 VL 135 IS 1 AR 011030 DI 10.1115/1.4006425 PG 7 WC Engineering, Mechanical SC Engineering GA 063IN UT WOS:000312989900030 ER PT J AU Wengraitis, S McCubbin, P Wade, MM Biggs, TD Hall, S Williams, LI Zulich, AW AF Wengraitis, Stephen McCubbin, Patrick Wade, Mary Margaret Biggs, Tracey D. Hall, Shane Williams, Leslie I. Zulich, Alan W. TI Pulsed UV-C Disinfection of Escherichia coli With Light-Emitting Diodes, Emitted at Various Repetition Rates and Duty Cycles SO PHOTOCHEMISTRY AND PHOTOBIOLOGY LA English DT Article ID INACTIVATION; ULTRAVIOLET; SYSTEM AB A 2010 study exposed Staphylococcus aureus to ultraviolet (UV) radiation and thermal heating from pulsed xenon flash lamps. The results suggested that disinfection could be caused not only by photochemical changes from UV radiation, but also by photophysical stress damage caused by the disturbance from incoming pulses. The study called for more research in this area. The recent advances in light-emitting diode (LED) technology include the development of LEDs that emit in narrow bands in the ultraviolet-C (UV-C) range (100280 nm), which is highly effective for UV disinfection of organisms. Further, LEDs would use less power, and allow more flexibility than other sources of UV energy in that the user may select various pulse repetition frequencies (PRFs), pulse irradiances, pulse widths, duty cycles and types of waveform output (e.g. square waves, sine waves, triangular waves, etc.). Our study exposed Escherichia coli samples to square pulses of 272 nm radiation at various PRFs and duty cycles. A statistically significant correlation was found between E. colis disinfection sensitivity and these parameters. Although our sample size was small, these results show promise and are worthy of further investigation. Comparisons are also made with pulsed disinfection by LEDs emitting at 365 nm, and pulsed disinfection by xenon flash lamps. C1 [Wengraitis, Stephen; Hall, Shane] USA, Inst Publ Hlth, Aberdeen Proving Ground, MD USA. [McCubbin, Patrick] OptiMetrics Inc, Abingdon, MD USA. [Wade, Mary Margaret; Biggs, Tracey D.; Williams, Leslie I.; Zulich, Alan W.] USA, Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD USA. RP Wengraitis, S (reprint author), USA, Inst Publ Hlth, Aberdeen Proving Ground, MD USA. EM steve.wengraitis@mail.us.army.mil NR 21 TC 5 Z9 5 U1 3 U2 37 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0031-8655 J9 PHOTOCHEM PHOTOBIOL JI Photochem. Photobiol. PD JAN-FEB PY 2013 VL 89 IS 1 BP 127 EP 131 DI 10.1111/j.1751-1097.2012.01203.x PG 5 WC Biochemistry & Molecular Biology; Biophysics SC Biochemistry & Molecular Biology; Biophysics GA 063IP UT WOS:000312990200017 PM 22803834 ER PT J AU Sagripanti, JL Voss, L Marschall, HJ Lytle, CD AF Sagripanti, Jose-Luis Voss, Luzie Marschall, Hans-Juergen Lytle, Carl David TI Inactivation of Vaccinia Virus by Natural Sunlight and by Artificial UVB Radiation SO PHOTOCHEMISTRY AND PHOTOBIOLOGY LA English DT Article ID HOST-CELL REACTIVATION; ULTRAVIOLET-RADIATION; MONOCLONAL-ANTIBODIES; SOLAR ULTRAVIOLET; MAMMALIAN-CELLS; SOLID-SURFACES; LIGHT; ALPHAVIRUSES; SENSITIVITY; BIODEFENSE AB This study determined the sensitivity of vaccinia virus, an orthopox virus commonly used as a surrogate for variola virus (etiological agent of smallpox), exposed to UVB radiation emitted by a solar simulator, or to direct natural sunlight. The data obtained indicate that: (1) the virucidal effect of natural sunlight can be mimicked adequately by an artificial light source with similar spectral characteristics in the UVB, (2) viral sensitivity to UVB or to solar radiation can be correlated with experimental data previously obtained with UVC, (3) the correlation factor between virus inactivation by solar radiation (measured at 300 +/- 5 nm) and by UVC (254 nm) is between 33 and 60, and (4) the sensitivity of viruses either dry on glass surfaces or in liquid suspension is similar when in the presence of similar amounts of cellular debris and growth media. The findings reported in this study should assist in estimating the threat posed by the persistence of virus during epidemics or after an accidental or intentional release. C1 [Sagripanti, Jose-Luis; Lytle, Carl David] USA, Res & Technol Directorate, Edgewood Chem Biol Ctr, Aberdeen, MD USA. [Voss, Luzie; Marschall, Hans-Juergen] WIS, Munster, Germany. RP Sagripanti, JL (reprint author), USA, Res & Technol Directorate, Edgewood Chem Biol Ctr, Aberdeen, MD USA. EM joseluis.sagripanti@us.army.mil NR 38 TC 3 Z9 3 U1 0 U2 16 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0031-8655 J9 PHOTOCHEM PHOTOBIOL JI Photochem. Photobiol. PD JAN-FEB PY 2013 VL 89 IS 1 BP 132 EP 138 DI 10.1111/j.1751-1097.2012.01207.x PG 7 WC Biochemistry & Molecular Biology; Biophysics SC Biochemistry & Molecular Biology; Biophysics GA 063IP UT WOS:000312990200018 PM 22816993 ER PT J AU Venturi, ML Mesbahi, AN Boehmler, JH Marrogi, AJ AF Venturi, Mark L. Mesbahi, Ali N. Boehmler, James H. Marrogi, Aizen J. TI Evaluating Sterile Human Acellular Dermal Matrix in Immediate Expander-Based Breast Reconstruction: A Multicenter, Prospective, Cohort Study SO PLASTIC AND RECONSTRUCTIVE SURGERY LA English DT Article ID ALLODERM; COMPLICATIONS; IMPLANT; OUTCOMES; SURGERY AB Background: Human acellular dermal matrices have gained increasing use in immediate expander-based breast reconstruction. However, some studies suggest that these grafts may be associated with a higher incidence of infection and seroma. To evaluate complication rates after matrix-based breast reconstruction, the authors conducted a prospective, multicenter, cohort study to evaluate a sterile human acellular dermal matrix in immediate expander-based breast reconstruction, specifically, to determine whether it offered a more favorable risk profile with respect to infection and seroma. A secondary purpose was to determine whether the sterilization process affects graft incorporation. Methods: The authors performed 65 consecutive tissue expander-based breast reconstructions in a cohort of patients over a 1-year period using a single protocol. Sterile human matrix was used in all cases. The patients were evaluated for early complications (infection, seroma) and graft incorporation at the time of exchange or definitive reconstruction. Biopsies were performed in the first 20 reconstructions to provide histologic correlation of graft incorporation. Results: Complications occurred in three breasts (4.6 percent), including one case of cellulitis (1.5 percent) and two cases of partial mastectomy flap necrosis (3.0 percent) that required debridement. There were no seromas or explantations. The grafts were incorporated in all cases and verified histologically in the first 20 biopsies. Conclusions: Sterile human acellular dermal matrix can offer reliable matrix incorporation and a low complication rate. Sterilization does not negatively impact incorporation of the graft. The infection and seroma rates in this prospective study compare favorably to those in previous studies with nonsterilized (aseptic) acellular dermal matrix. (Plast. Reconstr. Surg. 131: 9e, 2013.) C1 [Venturi, Mark L.] Georgetown Univ Hosp, Dept Plast Surg, Washington, DC 20007 USA. Ohio State Med Ctr, Dept Plast Surg, Columbus, OH USA. Walter Reed Army Med Ctr, Dept Pathol, Silver Spring, MD USA. Walter Reed Army Med Ctr, Area Lab Med, Silver Spring, MD USA. RP Venturi, ML (reprint author), Georgetown Univ Hosp, Dept Plast Surg, Washington, DC 20007 USA. FU Davol, Inc. (Warwick, R.I.) FX Dr. Venturi is a member of the speaker's bureau for Davol, Inc., and Allergan, Inc. Dr. Mesbahi is a member of the speaker's bureau for Davol, Inc. Neither of the other authors has any financial disclosures. This study was funded, in part, by an unrestricted research grant from Davol, Inc. (Warwick, R.I.). NR 25 TC 19 Z9 20 U1 1 U2 5 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0032-1052 J9 PLAST RECONSTR SURG JI Plast. Reconstr. Surg. PD JAN PY 2013 VL 131 IS 1 BP 9E EP 18E DI 10.1097/PRS.0b013e3182729d4f PG 10 WC Surgery SC Surgery GA 062DG UT WOS:000312898700002 PM 22990174 ER PT J AU Sztandera, LM Cardello, AV Winterhalter, C Schutz, H AF Sztandera, Les M. Cardello, Armand V. Winterhalter, Carole Schutz, Howard TI Identification of the most significant comfort factors for textiles from processing mechanical, handfeel, fabric construction, and perceived tactile comfort data SO TEXTILE RESEARCH JOURNAL LA English DT Article DE Properties; human sensory and comfort issues; measurement ID HUMAN PSYCHOLOGICAL PERCEPTIONS; CLOTHING SENSORY COMFORT; PLAIN-WOVEN FABRICS; NEURAL-NETWORK; BENDING BEHAVIOR; ELASTIC FIBER; PART 1 AB Engineered fabrics are desired for military protective clothing applications. Such fabrics, exhibiting high tactile comfort, can be computationally designed. Through the use of an extensive database that contains handfeel, mechanical, construction, and tactile comfort data for fabrics, desired comfort can be predicted by measuring a limited number of properties. Output systems can be optimized to exhibit the highest level of comfort by engineering a fabric with specific properties. Using an extensive fabric database, we identify the most significant handfeel, mechanical, and construction properties influencing tactile fabric comfort. This is done through the use of regression analysis of handfeel, mechanical, construction fabric properties, and perceived tactile comfort, using B un-standardized coefficients and Beta standardized coefficients. C1 [Sztandera, Les M.] Philadelphia Univ, Philadelphia, PA 19144 USA. [Cardello, Armand V.; Winterhalter, Carole] USA, Natick Soldier R D & E Ctr, Washington, DC USA. RP Sztandera, LM (reprint author), Philadelphia Univ, 4201 Henry Ave, Philadelphia, PA 19144 USA. EM SztanderaL@philau.edu FU US Department of Defense [W911QY-10-1-0002] FX This work was supported by the US Department of Defense ( grant number W911QY-10-1-0002). NR 30 TC 9 Z9 9 U1 2 U2 35 PU SAGE PUBLICATIONS LTD PI LONDON PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND SN 0040-5175 J9 TEXT RES J JI Text. Res. J. PD JAN PY 2013 VL 83 IS 1 BP 34 EP 43 DI 10.1177/0040517512438121 PG 10 WC Materials Science, Textiles SC Materials Science GA 059LP UT WOS:000312707200003 ER PT J AU Hanafi, HA El-Din, EMN El-Hossary, SSI Kaldas, RM Villinski, JT Furman, BD Fryauff, DJ AF Hanafi, Hanafi A. El-Din, El-Shaimaa M. Nour El-Hossary, Shabaan S. I. Kaldas, Rania M. Villinski, Jeffrey T. Furman, Barry D. Fryauff, David J. TI Experimental acquisition, development, and transmission of Leishmania tropica by Phlebotomus duboscqi SO ACTA TROPICA LA English DT Article DE Phlebotomus duboscqi; Leishmania tropica; Transmission; Vector competency ID ANTHROPONOTIC CUTANEOUS LEISHMANIASIS; SAND FLIES; EXPERIMENTAL-INFECTION; LUTZOMYIA-LONGIPALPIS; VECTOR; PSYCHODIDAE; DIPTERA; KENYA; PARASITE; SANDFLIES AB We report experimental infection and transmission of Leishmania tropica (Wright), by the blood-feeding sand fly Phlebotomus duboscqi (Neveu-Lemaire). Groups of laboratory-reared female sand flies that fed "naturally" on L tropica-infected hamsters, or artificially, via membrane feeding device, on a suspension of L tropica amastigotes, were dissected at progressive time points post-feeding. Acquisition, retention and development of L tropica through procyclic, nectomonad, and leptomonad stages to the infective metacyclic promastigote stage, and anterior progression of the parasites from abdominal midgut blood-meal to the thoracic midgut were demonstrated in both groups. Membrane feeding on the concentrated amastigote suspension led to metacyclic promastigote infections in 60% of sand flies, whereas only 3% of P. duboscqi that fed naturally on an infected hamster developed metacyclics. Sand flies from both groups re-fed on naive hamsters, but despite infections in 25-50% of membrane-fed and 2-3.5% of naturally fed flies, no skin lesions developed in the hamsters. After four months of observation these animals were euthanized and necropsied. Screening of the organs and tissue by polymerase cinain reaction (PCR) that targeted the small subunit RNA gene, amplified generic Leishmania DNA from liver, spleen, bone marrow, and blood, but only from hamsters bitten by membrane-infected P. duboscqi. These results are notable in demonstrating the ability of P. duboscqi, originating from Kenya, to acquire, retain, develop, and transmit a Turkish strain of L tropica originally isolated from a human case of cutaneous leishmaniasis. This marks the first demonstration of complete development and transmission of L tropica by a member of the Phlebotomus subgenus of sand flies. Published by Elsevier B.V. C1 [Hanafi, Hanafi A.; El-Din, El-Shaimaa M. Nour; El-Hossary, Shabaan S. I.; Kaldas, Rania M.; Villinski, Jeffrey T.; Furman, Barry D.; Fryauff, David J.] USN, Med Res Unit 3, Cairo, Egypt. RP Fryauff, DJ (reprint author), USN, Med Res Ctr, Walter Reed Army Inst Res, Mil Malaria Vaccine Program,Inst Review Board, 503 Robert Grant Ave, Silver Spring, MD 20910 USA. EM david.fryauff@med.navy.mil FU NMRDC, Bethesda, MD [00101.BUX.3408] FX The experiments reported herein were conducted in compliance with the Animal Welfare Act and in accordance with the principles set forth in the "Guide for the Care and Use of Laboratory Animals", Institute of Laboratory Animal Resources, National Research Council, National Academy Press, 1996. The research protocol and methods employed in this work were reviewed and approved by a duly constituted Institutional Animal Care and Use Committee (IACUC), NAMRU-3 Animal Use Protocol No. 08-01. All animals used in this work were cared for and maintained under conditions approved by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC). This work was supported by NMRDC, Bethesda, MD, Work Unit Number 00101.BUX.3408. NR 55 TC 2 Z9 2 U1 0 U2 9 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0001-706X J9 ACTA TROP JI Acta Trop. PD JAN PY 2013 VL 125 IS 1 BP 37 EP 42 DI 10.1016/j.actatropica.2012.09.001 PG 6 WC Parasitology; Tropical Medicine SC Parasitology; Tropical Medicine GA 055LG UT WOS:000312417200005 PM 22975149 ER PT J AU Patel, A Rudraraju, M Shen, L Palma-Vargas, J Foster, P AF Patel, Anish Rudraraju, Madhavi Shen, Luke Palma-Vargas, Juan Foster, Preston TI Graft Outcomes in Kidney Transplantation Alone with Concomitant Cirrhosis SO AMERICAN JOURNAL OF TRANSPLANTATION LA English DT Meeting Abstract CT 13th Annual State of the Art Winter Symposium of the American-Society-of-Transplant-Surgeons (ASTS) Held in Conjunction with the NATCO Symposium for Advanced Transplant Professionals CY JAN 31-FEB 03, 2013 CL Miami, FL SP Amer Soc Transplant Surg (ASTS), NATCO C1 [Patel, Anish] Brooke Army Med Ctr, Ft Sam Houston, TX 78234 USA. [Rudraraju, Madhavi; Shen, Luke; Palma-Vargas, Juan; Foster, Preston] Texas Transplant Inst MSTH, San Antonio, TX USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 1600-6135 J9 AM J TRANSPLANT JI Am. J. Transplant. PD JAN PY 2013 VL 13 SU 2 SI SI BP 90 EP 90 PG 1 WC Surgery; Transplantation SC Surgery; Transplantation GA 057CT UT WOS:000312540200109 ER PT J AU Wade, CE Mora, AG Shields, BA Pidcoke, HF Baer, LA Chung, KK Wolf, SE AF Wade, Charles E. Mora, Alejandra G. Shields, Beth A. Pidcoke, Heather F. Baer, Lisa A. Chung, Kevin K. Wolf, Steven E. TI Signals from fat after injury: Plasma adipokines and ghrelin concentrations in the severely burned SO CYTOKINE LA English DT Article; Proceedings Paper CT 69th Annual Meeting of the American-Association-for-the-Surgery-of-Trauma CY SEP 22-25, 2010 CL Boston, MA SP Amer Assoc Surg Trauma (AAST) DE Leptin; Adiponectin; Resistin; Metabolism; Inflammation ID CARE-UNIT PATIENTS; CRITICAL ILLNESS; SERUM ADIPONECTIN; LEPTIN; POSTBURN; SEPSIS; ORGAN; RATS; INFLAMMATION; DYSFUNCTION AB Introduction: Hypermetabolism is universal in the severely burned and is characterized by catabolism of lean mass and body fat with associated insulin resistance. Adipokines are likely to play a role in these changes but have not been identified to date in burn patients. Methods: From a single burn ICU, 17 burn patients with an expected stay >14 days were studied. Study period began within 14 days of admission. Over 7 days, plasma samples were collected for measurement of leptin, adiponectin, resistin, ghrelin, insulin, and cortisol by ELISA. For comparison, samples from 15 healthy controls of similar age, BMI, and blood glucose were obtained. Results: Mean age was 33 +/- 17 years and BMI 26 +/- 3.4. Average burn size was 45 +/- 20% TBSA and ISS 32 +/- 10 with 72% having inhalation injury; in-hospital mortality was 29%. Estimated energy needs were 3626 +/- 710 kcal, of which 84 +/- 21% were met by enteral feeding with intensive insulin treatment (glucose 80-110 mg/ml). Using the homeostasis model assessment of insulin resistance, burned subjects were more resistant than controls (17 +/- 11.3 and 8 +/- 10.0). Insulin levels were elevated (57 +/- 35.6 mu U/ml in burned subject vs. 26 +/- 31.1 mu U/ml in controls), and cortisol concentrations increased (50 +/- 41.2 mu g/dl vs. 12 +/- 3.9 mu g/dl). These traditional hormone changes were associated with increased resistin (16.6 +/- 5.5 ng/ml vs. 3.8 +/- 0.9 ng/ml) and decreased leptin (8.8 +/- 8.9 ng/ml vs. 19.4 +/- 23.5 ng/ml), adiponectin (9 +/- 3.5 ng/ml vs. 17 +/- 10.2 ng/ml), and ghrelin (0.37 +/- 0.14 ng/ml vs.0.56 +/- 0.26 ng/ml). Conclusion: Patients with burns, who are characteristically hypermetabolic with hypercortisolism and insulin resistant, have significant changes in adipokine levels that appear independent of the magnitude of initial injury or metabolic derangement. In addition, suppression of ghrelin in the presence of decreased leptin and adiponectin levels in combination with increased insulin and resistin levels represent unexpected changes in the metabolic milieu of the injured patient possibly due to dramatic activation of inflammatory pathways, indicating strategies for treatment. (C) 2012 Elsevier Ltd. All rights reserved. C1 [Wade, Charles E.; Baer, Lisa A.] Univ Texas Hlth Sci Ctr Houston, Houston, TX 77030 USA. [Mora, Alejandra G.; Shields, Beth A.; Pidcoke, Heather F.; Chung, Kevin K.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA. [Wolf, Steven E.] Univ Texas SW Med Ctr Dallas, Dallas, TX 75390 USA. RP Wade, CE (reprint author), Univ Texas Hlth Sci Ctr Houston, 6431 Fannin St,MSB 5-204, Houston, TX 77030 USA. EM charles.e.wade@uth.tmc.edu; Alex.Mora1@us.army.mil; Beth.Shields@amedd.army.mil; Heather.Pidcoke@us.army.mil; Lisa.Baer@uth.tmc.edu; Kevin.Chung@amedd.army.mil; Steven.Wolf@utsouthwestern.edu OI Wolf, Steven/0000-0003-2972-3440 FU NIGMS NIH HHS [1 R01 GM063120-04, R01 GM063120] NR 29 TC 5 Z9 6 U1 0 U2 6 PU ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD PI LONDON PA 24-28 OVAL RD, LONDON NW1 7DX, ENGLAND SN 1043-4666 J9 CYTOKINE JI Cytokine PD JAN PY 2013 VL 61 IS 1 BP 78 EP 83 DI 10.1016/j.cyto.2012.08.031 PG 6 WC Biochemistry & Molecular Biology; Cell Biology; Immunology SC Biochemistry & Molecular Biology; Cell Biology; Immunology GA 056UR UT WOS:000312517400013 PM 23021431 ER PT J AU Rohr, JR Johnson, P Hickey, CW Helm, RC Fritz, A Brasfield, S AF Rohr, Jason R. Johnson, Philip Hickey, Christopher W. Helm, Roger C. Fritz, Alyce Brasfield, Sandra TI Implications of global climate change for natural resource damage assessment, restoration, and rehabilitation SO ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY LA English DT Article DE Contaminant; Baseline; Hazard assessment; Environmental policy; Tipping point ID ASSISTED COLONIZATION; CONTAMINANTS; IMPACTS; DISEASE; FOREST; MANAGEMENT; RESPONSES; DECLINES AB Various international and national regulations hold polluters liable for the cleanup of released hazardous substances and the restoration/rehabilitation of natural resources to preincident baseline conditions, a process often referred to as natural resource damage assessment and restoration (NRDAR). Here, we, the authors, describe how global climate change (GCC) will challenge each of the steps of NRDAR processes and offer eight recommendations to improve these processes in light of GCC. First, we call for a better understanding of the net effects of GCC and contaminants on natural resources. Second, we urge facilities and environmental managers to plan for GCC-related factors that are expected to increase the probability of contaminant releases. Third, we suggest re-evaluating definitions of baseline and reference conditions given that GCC will alter both their trajectories and variability. Fourth, we encourage long-term monitoring to improve the quantification of baseline conditions that will change as climate changes. This will enhance the accuracy of injury assessments, the effectiveness of restoration, and the detection of early warning signs that ecosystems are approaching tipping points. Fifth, in response to or anticipation of GCC, restoration projects may need to be conducted in areas distant from the site of injury or focused on functionally equivalent natural resources; thus, community involvement in NRDAR processes will be increasingly important. Sixth, we promote using NRDAR restoration projects as opportunities to mitigate GCC-related impacts. Seventh, we recommend adaptive management approaches to NRDAR processes and communication of successes and failures widely. Finally, we recommend focusing on managing the stressors that might be exacerbated by GCC, such as pollution and habitat loss, because there is a long history of successfully mitigating these stressors, which can be more easily managed on local scales than climate change. We believe that adoption of these recommendations will lead to a more efficacious NRDAR process, despite the challenges posed by climate change. Environ. Toxicol. Chem. 2013;32:93101. (c) 2012 SETAC C1 [Rohr, Jason R.] Univ S Florida, Dept Integrat Biol, Tampa, FL 33620 USA. [Johnson, Philip] US Fish & Wildlife Serv, Anchorage, AK USA. [Hickey, Christopher W.] Natl Inst Water & Atmospher Res, Hamilton, New Zealand. [Helm, Roger C.] US Fish & Wildlife Serv, Div Environm Qual, Arlington, VA USA. [Fritz, Alyce] NOAA, Off Response & Restorat, Seattle, WA USA. [Brasfield, Sandra] USA, Engineer Res & Dev Ctr, Environm Lab, Vicksburg, MS USA. RP Rohr, JR (reprint author), Univ S Florida, Dept Integrat Biol, Tampa, FL 33620 USA. EM jasonrohr@gmail.com RI Hickey, Christopher/E-9931-2013 FU U.S. Department of Agriculture [NRI 2008-00622 20, 2008-01785]; U.S. Environmental Protection Agency [STAR R83-3835, CAREER 83518801] FX We thank W. Landis for comments. J. Rohr was supported by grants from the U.S. Department of Agriculture (NRI 2008-00622 20 and 2008-01785) and the U.S. Environmental Protection Agency (STAR R83-3835 and CAREER 83518801). The opinions are those of the authors, who are solely responsible for the content. The authors declare no conflicts of interest. NR 61 TC 12 Z9 12 U1 1 U2 56 PU WILEY-BLACKWELL PI HOBOKEN PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA SN 0730-7268 J9 ENVIRON TOXICOL CHEM JI Environ. Toxicol. Chem. PD JAN PY 2013 VL 32 IS 1 BP 93 EP 101 DI 10.1002/etc.2036 PG 9 WC Environmental Sciences; Toxicology SC Environmental Sciences & Ecology; Toxicology GA 057EQ UT WOS:000312545700011 PM 23097077 ER PT J AU Fulco, CS Beidleman, BA Muza, SR AF Fulco, Charles S. Beidleman, Beth A. Muza, Stephen R. TI Effectiveness of Preacclimatization Strategies for High-Altitude Exposure SO EXERCISE AND SPORT SCIENCES REVIEWS LA English DT Review DE hypobaric hypoxia; normobaric hypoxia; staging; acute mountain sickness; moderate altitude residence; altitude acclimatization; endurance exercise performance ID ACUTE MOUNTAIN-SICKNESS; EXERCISE PERFORMANCE; CARBOHYDRATE SUPPLEMENTATION; VENTILATORY ACCLIMATIZATION; ENDURANCE PERFORMANCE; NORMOBARIC HYPOXIA; HYPOBARIC HYPOXIA; 4300 METERS; RESIDENTS; RESPONSES AB FULCO, C. S., B. A. BEIDLEMAN, and S. R. MUZA. Effectiveness of preacclimatization strategies for high-altitude exposure. Exerc. Sport Sci. Rev., Vol. 41, No. 1, pp. 55-63, 2013. Acute mountain sickness (AMS) and large decrements in endurance exercise performance occur when unacclimatized individuals rapidly ascend to high altitudes. Six altitude and hypoxia preacclimatization strategies were evaluated to determine their effectiveness for minimizing AMS and improving performance during altitude exposures. Strategies using hypobaric chambers or true altitude were much more effective overall than those using normobaric hypoxia (breathing, <20.9% oxygen). C1 [Fulco, Charles S.; Beidleman, Beth A.; Muza, Stephen R.] USA, Environm Med Res Inst, Thermal & Mt Med Div, Natick, MA 01760 USA. RP Fulco, CS (reprint author), USARIEM, Thermal & Mt Med Div, 42 Kansas St, Natick, MA 01760 USA. EM charles.fulco@us.army.mil NR 29 TC 23 Z9 24 U1 4 U2 34 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0091-6331 J9 EXERC SPORT SCI REV JI Exerc. Sport Sci. Rev. PD JAN PY 2013 VL 41 IS 1 BP 55 EP 63 DI 10.1097/JES.0b013e31825eaa33 PG 9 WC Physiology; Sport Sciences SC Physiology; Sport Sciences GA 058WN UT WOS:000312665700009 PM 22653279 ER PT J AU Read, CM Knight, TW Allen, KS AF Read, Carey M., Jr. Knight, Travis W. Allen, Kenneth S. TI Development of a multi-tiered recycling strategy with a sodium-cooled Heterogeneous Innovative Burner Reactor SO PROGRESS IN NUCLEAR ENERGY LA English DT Article DE Sodium-cooled fast reactor; ERANOS; VISION; Fast reactor recycle; Multi-tiered recycle AB The Sodium-Cooled Heterogeneous Innovative Burner Reactor (SCHIBR) model created at the University of South Carolina uses heterogeneous minor actinide targets. To improve minor actinide transmutation, a hybrid fuel management scheme is utilized involving initially moderated assemblies on the core periphery followed by a second period of irradiation in a fast flux with the moderating rods removed. A multi-tiered recycling strategy was developed to increase plutonium utilization in the SCHIBR model through the recycle of the driver fuel. An equilibrium fuel cycle was evaluated with the computer code ERANOS to determine the improvements in fuel utilization, reduction in high level waste, and safety of the SCHIBR design. Fuel depletion studies were conducted to determine the composition of input and output streams in order to develop reactor recipes for use in the fuel cycle simulation code, VISION. The once-through SCHIBR model reduces the radiotoxicity of high level waste by 66% of the once-through LWR model after 300 years in storage. The multi-tiered recycling strategy offers improvements over the previous once-through SCHIBR model by reducing the radiotoxicity by 86% after 300 years in storage. (C) 2012 Elsevier Ltd. All rights reserved. C1 [Read, Carey M., Jr.; Knight, Travis W.] Univ S Carolina, Dept Mech Engn, Nucl Engn Program, Columbia, SC 29208 USA. [Allen, Kenneth S.] US Mil Acad, Dept Phys & Nucl Engn, West Point, NY 10996 USA. RP Knight, TW (reprint author), Univ S Carolina, Dept Mech Engn, Nucl Engn Program, 300 Main St, Columbia, SC 29208 USA. EM knighttw@engr.sc.edu OI Knight, Travis/0000-0002-8517-7395 FU Nuclear Regulatory Commission FX This research was supported in part by a fellowship from the Nuclear Regulatory Commission. High performance computing support for the MCNPX 2.6.0 and ERANOS 2.1 calculations was provided by the High Performance Computing Cluster (NICK) at the University of South Carolina. NR 10 TC 0 Z9 0 U1 1 U2 3 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0149-1970 J9 PROG NUCL ENERG JI Prog. Nucl. Energy PD JAN PY 2013 VL 62 BP 72 EP 78 DI 10.1016/j.pnucene.2012.09.008 PG 7 WC Nuclear Science & Technology SC Nuclear Science & Technology GA 056SM UT WOS:000312511700009 ER PT J AU Sondheimer, RM Toner, K Wilson, I AF Sondheimer, Rachel Milstein Toner, Kevin Wilson, Isaiah, III TI Cadet Perceptions of Military and Civilian Ideology: A Research Note SO ARMED FORCES & SOCIETY LA English DT Article DE civil-military relations; professionalism; civil-military gap; ideology; West Point AB Evidence of an actual or perceived gap in ideological beliefs between civilian and military communities informs current debates on the military and its relationship to broader society. The authors examine one cohort of the military and its members' perception of their own ideology in relation to their civilian counterparts using a 2009 survey of cadets at the United States Military Academy. The authors ascertain cadet perceptions of (1) cadet ideological leanings on individual and aggregate levels, (2) the ideological leanings of the civilian population, and (3) the civilian population's assessment of the military's ideological leanings. The authors attempt to discern whether or not this military subpopulation perceives itself as different from the rest of society. The authors find that while members of the Army's future officer corps perceive themselves as more conservative than their civilian peers and society writ large, as a group they hold rather moderate political views. C1 [Sondheimer, Rachel Milstein; Toner, Kevin; Wilson, Isaiah, III] US Mil Acad, Dept Social Sci, West Point, NY 10996 USA. RP Sondheimer, RM (reprint author), US Mil Acad, Dept Social Sci, 607 Cullum Rd, West Point, NY 10996 USA. EM Rachel.sondheimer@usma.edu NR 6 TC 0 Z9 0 U1 2 U2 3 PU SAGE PUBLICATIONS INC PI THOUSAND OAKS PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA SN 0095-327X J9 ARMED FORCES SOC JI Armed Forces Soc. PD JAN PY 2013 VL 39 IS 1 BP 124 EP 134 DI 10.1177/0095327X12442304 PG 11 WC Political Science; Sociology SC Government & Law; Sociology GA 052MD UT WOS:000312201000006 ER PT J AU Hicks, RP Abercrombie, JJ Wong, RK Leung, KP AF Hicks, R. P. Abercrombie, J. J. Wong, R. K. Leung, K. P. TI Antimicrobial peptides containing unnatural amino acid exhibit potent bactericidal activity against ESKAPE pathogens SO BIOORGANIC & MEDICINAL CHEMISTRY LA English DT Article DE Antimicrobial peptides; Unusual amino acids; ESKAPE; MIC; MBC; Cellular toxicity ID SELECTIVE ANTIBIOTIC PEPTIDES; MEMBRANE MODEL SYSTEMS; DE-NOVO DESIGN; CATIONIC PEPTIDES; DRUG DISCOVERY; LYSYL-PHOSPHATIDYLGLYCEROL; ACINETOBACTER-BAUMANNII; STAPHYLOCOCCUS-AUREUS; BIOLOGICAL-ACTIVITY; LIPID INTERACTIONS AB A series of 36 synthetic antimicrobial peptides containing unnatural amino acids were screened to determine their effectiveness to treat Enterococcus faecium, Staphylococcus aureus, Klebsiella pnemoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species (ESKAPE) pathogens, which are known to commonly infect chronic wounds. The primary amino acid sequences of these peptides incorporate either three or six dipeptide units consisting of the unnatural amino acids Tetrahydroisoquinolinecarboxylic acid (Tic) and Octahydroindolecarboxylic acid (Oic). The Tic-Oic dipeptide units are separated by SPACER amino acids with specific physicochemical properties that control how these peptides interact with bacterial cell membranes of different chemical compositions. These peptides exhibited minimum inhibitory concentrations (MIC) against these pathogens in the range from >100 to 6.25 mu g/mL. The observed diversity of MIC values for these peptides against the various bacterial strains are consistent with our hypothesis that the complementarity of the physicochemical properties of the peptide and the lipid of the bacteria's cell membrane determines the resulting antibacterial activity of the peptide. Published by Elsevier Ltd. C1 [Abercrombie, J. J.; Wong, R. K.; Leung, K. P.] USA, Inst Surg Res, Dent & Trauma Res Detachment, Ft Sam Houston, TX 78234 USA. [Hicks, R. P.] E Carolina Univ, Dept Chem, Greenville, NC 27858 USA. RP Leung, KP (reprint author), USA, Inst Surg Res, Dent & Trauma Res Detachment, 3650 Chambers Pass,Bldg 3610, Ft Sam Houston, TX 78234 USA. EM kai.leung@amedd.army.mil FU US Army Medical Research and Materiel Command, Military Infectious Diseases Research Directorate FX This work was partly supported by the US Army Medical Research and Materiel Command, Military Infectious Diseases Research Directorate. NR 82 TC 15 Z9 15 U1 2 U2 34 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0968-0896 J9 BIOORGAN MED CHEM JI Bioorg. Med. Chem. PD JAN 1 PY 2013 VL 21 IS 1 BP 205 EP 214 DI 10.1016/j.bmc.2012.10.039 PG 10 WC Biochemistry & Molecular Biology; Chemistry, Medicinal; Chemistry, Organic SC Biochemistry & Molecular Biology; Pharmacology & Pharmacy; Chemistry GA 053MJ UT WOS:000312275500019 PM 23199484 ER PT J AU Moser, RD Rodriguez, OL Hidalgo-Hernandez, RG Malone, PG Chandler, MQ Allison, PG Weiss, CA Torres-Cancel, K AF Moser, R. D. Rodriguez, O. L. Hidalgo-Hernandez, R. G. Malone, P. G. Chandler, M. Q. Allison, P. G. Weiss, C. A., Jr. Torres-Cancel, Kevin TI Infilling of porous materials with various polymorphs of calcium carbonate by an electromigration technique SO JOURNAL OF APPLIED ELECTROCHEMISTRY LA English DT Article DE Electromigration; Calcium carbonate; Biomimetic; Biomedical applications ID ELECTROPHORETIC DEPOSITION; CERAMICS; MECHANISMS; MEMBRANES AB Recent interest in bio-inspired materials has led to the development of techniques that can be used to synthesize hierarchical structures with controlled morphology and mineralogy. One such technique investigated in this study consists of the use of electromigration and electrodeposition techniques to deposit mineral phases with controlled morphology and mineralogy by infilling a predefined porous templates. Here, the utility of precipitating various polymorphs of calcium carbonate in three-dimensional templates is demonstrated. Applied potentials and times were varied while scanning electron microscopy and X-ray diffraction were used to determine polymorph formed and its morphology. It was found that higher applied potentials and shorter operating times resulted in the formation of metastable polymorphs of calcium carbonate (e.g., vaterite) that infilled the porous media. Results provide insights for developing bio-inspired composite materials for various structural and medical applications, such as synthetic bone. C1 [Moser, R. D.; Hidalgo-Hernandez, R. G.; Malone, P. G.; Chandler, M. Q.; Allison, P. G.; Weiss, C. A., Jr.; Torres-Cancel, Kevin] USA, Geotech & Struct Lab, Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA. [Rodriguez, O. L.] Univ Puerto Rico, Dept Mech Engn, Mayaguez, PR 00680 USA. RP Moser, RD (reprint author), USA, Geotech & Struct Lab, Engineer Res & Dev Ctr, Halls Ferry Rd, Vicksburg, MS 39180 USA. EM robert.d.moser@usace.army.mil OI Allison, Paul/0000-0002-9041-237X FU U.S. Army ERDC Center-Directed Research Program FX The Authors would like to acknowledge the support for this work provided by the U.S. Army ERDC Center-Directed Research Program. The Authors would also like to thank the staff and facilities of the Geotechnical and Structures Laboratory's Concrete and Materials Branch for supporting the experimental work. Permission to publish was granted by Director, Geotechnical and Structures Laboratory, U.S. Army Engineer Research and Development Center. NR 23 TC 0 Z9 0 U1 0 U2 25 PU SPRINGER PI DORDRECHT PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS SN 0021-891X J9 J APPL ELECTROCHEM JI J. Appl. Electrochem. PD JAN PY 2013 VL 43 IS 1 BP 73 EP 83 DI 10.1007/s10800-012-0501-6 PG 11 WC Electrochemistry SC Electrochemistry GA 052PG UT WOS:000312209600009 ER PT J AU Levy, JA Podeszwa, DA Lebus, G Ho, CA Wimberly, RL AF Levy, Jeffrey A. Podeszwa, David A. Lebus, Geof Ho, Christine A. Wimberly, Robert L. TI Acute Complications Associated With Removal of Flexible Intramedullary Femoral Rods Placed for Pediatric Femoral Shaft Fractures SO JOURNAL OF PEDIATRIC ORTHOPAEDICS LA English DT Article DE removal of intramedullary rods; pediatric femur fractures; flexible intramedullary rods; Ender rods ID TITANIUM ELASTIC NAILS; DIAPHYSEAL FEMUR FRACTURES; CHILDREN; FIXATION; IMPLANTS AB Background: The American Academy of Orthopaedic Surgeons position statement on the treatment of pediatric femoral shaft fractures could not comment on the safety of flexible intramedullary (IM) rod removal because of a lack of published evidence. This study reviews the acute complications of flexible IM rod removal from pediatric patients treated for femoral shaft fractures. Methods: A retrospective clinical and radiographic analysis at a single institution over a 5-year period. Demographic and radiographic parameters were analyzed to determine their influence on intraoperative and immediate postoperative complications. Results: One hundred sixty-three subjects (133 males, 30 females), mean age of 9.3 +/- 2.8 years (range, 2.7 to 14.8 y) and mean weight of 34.4 +/- 15.3 kg (range, 14.0 to 139.0 kg), underwent femoral flexible IM rod removal a mean 12.4 +/- 10.8 months (range, 2.4 to 63.8 mo) after placement with mean operative time of 51.1 +/- 22.3 minutes (range, 10 to 131 min). One hundred fifty-one subjects (92.6%) had stainless-steel Ender rods and the remaining nails were titanium. There were no significant demographic, intraoperative, or radiographic differences comparing subjects with Ender versus titanium rods. Indications for rod removal were pain at insertion site, family request, or surgeon's recommendation. There were 4 (2.5%) minor intraoperative difficulties, including the inability to remove 1 of 2 rods secondary to IM migration (n = 1) and complete bone overgrowth at insertion site resulting in prolonged extraction time (n = 3). Three of the 4 subjects had the rods placed >60 months before removal. Immediately postoperative (n = 134), there were 4 (3.0%) complications, including superficial wound infection (n = 3, 2.2%) and knee contracture (n = 1, 0.8%). Subjects were released to full activities at a mean 4.7 +/- 1.8 weeks postoperatively with no known postoperative fractures. Conclusions: The rate of intraoperative and immediate postoperative complications is low. Neither patient demographics, fracture characteristics, nor operative technique influenced the complication rate. Intraoperative difficulties may be minimized with removal of rods before signs of overgrowth. C1 [Podeszwa, David A.; Lebus, Geof; Ho, Christine A.; Wimberly, Robert L.] Texas Scottish Rite Hosp Crippled Children, Dept Orthopaed Surg, Dallas, TX 75235 USA. [Levy, Jeffrey A.] Tripler Army Med Ctr, Dept Orthopaed Surg, Honolulu, HI 96859 USA. [Podeszwa, David A.; Lebus, Geof; Ho, Christine A.; Wimberly, Robert L.] Childrens Med Ctr, Dallas, TX 75235 USA. RP Podeszwa, DA (reprint author), Texas Scottish Rite Hosp Crippled Children, Dept Orthopaed Surg, 1935 Med Dist Dr,E2300, Dallas, TX 75235 USA. EM david.podeszwa@childrens.com OI Ho, Christine/0000-0002-6710-6040 NR 18 TC 6 Z9 8 U1 0 U2 2 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0271-6798 EI 1539-2570 J9 J PEDIATR ORTHOPED JI J. Pediatr. Orthop. PD JAN-FEB PY 2013 VL 33 IS 1 BP 43 EP 47 DI 10.1097/BPO.0b013e318279c544 PG 5 WC Orthopedics; Pediatrics SC Orthopedics; Pediatrics GA 053FJ UT WOS:000312256100010 PM 23232378 ER PT J AU Kim, JK Dotson, B Thomas, S Nelson, KC AF Kim, Julie K. Dotson, Bert Thomas, Sean Nelson, Kelly C. TI Standardized patient identification and specimen labeling: A retrospective analysis on improving patient safety SO JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY LA English DT Article DE labeling errors; pathology specimens; patient safety; safety protocol; specimen identification; specimen labeling errors ID PATHOLOGY; QUALITY; ERRORS AB Background: There is an increased risk of specimen labeling errors with the generation of a high volume of pathology specimens. Measuring specimen labeling accuracy has been suggested as a possible measure for patient safety. Objective: We sought to identify operational areas for improvement around specimen handling with the institution of a standardized specimen labeling protocol in the Duke University Medical Center Department of Dermatology. The average rates of specimen labeling events before and after implementation of this protocol were analyzed to determine the efficacy of this systematic approach. Methods: We collected the monthly aggregated rates of specimen labeling events occurring with skin specimens processed through the Duke University Medical Center Department of Pathology from December 2008 through June 2011. The average monthly rates of events per 1000 cases for the time periods from December 2008 through March 2010 and June 2010 through September 2011 were compared. Results: The data collected showed a statistically significant decline in the average monthly rate of specimen labeling errors after institution of the protocol. Before implementation, specimen labeling events occurred at a rate of 5.79 events per 1000 with a decrease to 3.53 events per 1000 after integration of this system (P = .028). Limitations: Limitations of this study include possible sampling error and regression toward the mean. Conclusions: Low-cost, process-driven interventions are effective in the reduction of specimen handling errors. (J Am Acad Dermatol 2013;68:53-6.) C1 [Kim, Julie K.; Thomas, Sean; Nelson, Kelly C.] Duke Univ, Med Ctr, Dept Dermatol, Durham, NC 27710 USA. [Dotson, Bert] Duke Univ, Med Ctr, Dept Pathol, Durham, NC 27710 USA. [Thomas, Sean] US Army Med Command, San Antonio, TX USA. RP Nelson, KC (reprint author), Duke Univ, Med Ctr, Dept Dermatol, Box 3135,200 Trent Dr,Room 4033, Durham, NC 27710 USA. EM Kelly.nelson@duke.edu NR 7 TC 5 Z9 5 U1 0 U2 6 PU MOSBY-ELSEVIER PI NEW YORK PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA SN 0190-9622 J9 J AM ACAD DERMATOL JI J. Am. Acad. Dermatol. PD JAN PY 2013 VL 68 IS 1 BP 53 EP 56 DI 10.1016/j.jaad.2012.06.017 PG 4 WC Dermatology SC Dermatology GA 053KR UT WOS:000312270900011 PM 22841126 ER PT J AU Pender, RJ Shiels, AB Bialic-Murphy, L Mosher, SM AF Pender, Richard J. Shiels, Aaron B. Bialic-Murphy, Lalasia Mosher, Stephen M. TI Large-scale rodent control reduces pre- and post-dispersal seed predation of the endangered Hawaiian lobeliad, Cyanea superba subsp superba (Campanulaceae) SO BIOLOGICAL INVASIONS LA English DT Article DE Alien invasive species; Captive-feeding trials; Frugivory; Mus musculus; Plant recruitment; Rattus rattus ID NORTHERN OFFSHORE ISLANDS; RATTUS-EXULANS PEALE; NEW-ZEALAND; INTRODUCED RODENTS; INVASIVE RATS; SMALL MAMMALS; DRY FOREST; ERADICATION; RECRUITMENT; DISPERSAL AB Large-scale rodent control can help to manage endangered species that are vulnerable to invasive rodent consumption. A 26 ha rodent snap-trap grid was installed in montane forest on Oahu Island, Hawaii, in order to protect endangered snails and plants. To assess the effectiveness of this trapping operation in reducing fruit consumption and seed predation of the endangered Hawaiian lobeliad, Cyanea superba subsp. superba, pre- and post-dispersal C. superba fruit consumption were monitored for 36 plants at the site with rodent control (Kahanahaiki) and 42 plants at an adjacent site without rodent control (Pahole). Over 47 % of all monitored fruit were eaten on the plants at Pahole compared to 4 % at Kahanahaiki. Images captured using motion-sensing cameras suggest that black rats (Rattus rattus) were the only pre-dispersal fruit consumers. To quantify post-dispersal fruit consumption, and to identify the culprit frugivore(s), mature fruit were placed in tracking tunnels positioned on the forest floor and checked daily. At Pahole, all of the fruit were consumed by rats compared to 29 % at Kahanahaiki. Lastly, to determine if rodents from the sites were predators or dispersers of C. superba seed, fruit were fed to captive black rats and house mice (Mus musculus). Black rats consumed entire fruit, killing all the seed, while mice did little damage to the fruit and seed. Therefore, large-scale rat trapping can directly benefit the reproduction of C. superba subsp. superba. Controlling black rats at restoration sites appears integral to the successful restoration of this endangered plant species. C1 [Pender, Richard J.; Bialic-Murphy, Lalasia; Mosher, Stephen M.] Univ Hawaii Manoa, Dept Bot, Pacific Cooperat Studies Unit, Honolulu, HI 96822 USA. [Shiels, Aaron B.] Natl Wildlife Res Ctr, USDA, APHIS, Hawaii Field Stn, Hilo, HI 96721 USA. [Bialic-Murphy, Lalasia; Mosher, Stephen M.] US Army Garrison, Oahu Army Nat Resources Program, Environm Div, Directorate Publ Works, Schofield Barracks, HI 96857 USA. [Mosher, Stephen M.] USN, Naval Facil Engn Command Marianas, Santa Rita, GU 96915 USA. RP Pender, RJ (reprint author), Univ Hawaii Manoa, Dept Bot, Pacific Cooperat Studies Unit, 3190 Maile Way, Honolulu, HI 96822 USA. EM pender@hawaii.edu FU Oahu Army Natural Resources Program (OANRP); Fulbright New Zealand; John R. Templin Scholarship FX We thank the Oahu Army Natural Resources Program (OANRP) for funding and logistical support of this project-we are especially grateful for the many staff members that helped with the intensive and on-going rodent trapping at Kahanahaiki. We thank both OANRP and the Pahole Natural Area Reserve managers (State of Hawaii) for land access, and Don Drake, Kapua Kawelo, Matthew Keir, Clifford Morden, Julia Rowe, Lauren Weisenberger, and two anonymous reviewers for their helpful comments on an earlier draft of this manuscript. RJP and ABS wish to thank the Pacific Cooperative Studies Unit and Clifford Morden for providing logistical support. RJP gratefully acknowledges the financial support provided by Fulbright New Zealand and the John R. Templin Scholarship. This research was approved by the University of Hawaii Animal Use and Care Committee. NR 45 TC 6 Z9 6 U1 11 U2 95 PU SPRINGER PI DORDRECHT PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS SN 1387-3547 J9 BIOL INVASIONS JI Biol. Invasions PD JAN PY 2013 VL 15 IS 1 BP 213 EP 223 DI 10.1007/s10530-012-0280-3 PG 11 WC Biodiversity Conservation; Ecology SC Biodiversity & Conservation; Environmental Sciences & Ecology GA 051PZ UT WOS:000312140800017 ER PT J AU Nilakantan, G Wetzel, ED Bogetti, TA Gillespie, JW AF Nilakantan, Gaurav Wetzel, Eric D. Bogetti, Travis A. Gillespie, John W., Jr. TI A deterministic finite element analysis of the effects of projectile characteristics on the impact response of fully clamped flexible woven fabrics SO COMPOSITE STRUCTURES LA English DT Article DE Aramid fiber; Fabrics/textiles; Impact behavior; Finite element analysis (FEA); Projectile characteristics ID BALLISTIC PERFORATION; DIFFERENT GEOMETRY; STRENGTH; PERFORMANCE AB In this paper the effects of projectile size and shape on the impact response of a single-layer fully-clamped flexible woven fabric are numerically studied using a finite element analysis. Six projectiles of spherical, cylindrical, and conical shapes with varying sizes but of the same mass are considered. A yam-level fabric model with a deterministic implementation of experimental mean yarn tensile strength and inter-yarn friction is considered. A single impact velocity is chosen for the six different projectiles to compare the fabric impact responses in terms of residual projectile velocities, fabric energy dissipations, and number of failed yarns. Two impact locations are considered, at a yarn cross-over and at the gap in-between the yarns. The sensitivity of fabric impact response to projectile geometrical characteristics and impact location is demonstrated. (c) 2012 Elsevier Ltd. All rights reserved. C1 [Gillespie, John W., Jr.] Univ Delaware, Dept Civil & Environm Engn, Newark, DE 19716 USA. [Nilakantan, Gaurav; Gillespie, John W., Jr.] Univ Delaware, Ctr Composite Mat, Newark, DE 19716 USA. [Gillespie, John W., Jr.] Univ Delaware, Dept Mat Sci & Engn, Newark, DE 19716 USA. [Wetzel, Eric D.; Bogetti, Travis A.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Gillespie, JW (reprint author), Univ Delaware, Dept Civil & Environm Engn, Newark, DE 19716 USA. EM gillespi@udel.edu RI Nilakantan, Gaurav/B-8643-2012 OI Nilakantan, Gaurav/0000-0002-5375-9681 FU Army Research Laboratory [W911NF-06-2-0011] FX This research was sponsored by the Army Research Laboratory and was accomplished under Cooperative Agreement Number W911NF-06-2-0011. The views and conclusions contained in this document are those of the authors and should not be interested as representing the official policies, either expressed or implied, of the Army Research Laboratory or the US Government. The US Government is authorized to reproduce and distribute reprints for Government purposes notwithstanding any copyright notation herein. NR 15 TC 7 Z9 7 U1 1 U2 9 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0263-8223 J9 COMPOS STRUCT JI Compos. Struct. PD JAN PY 2013 VL 95 BP 191 EP 201 DI 10.1016/j.compstruct.2012.07.023 PG 11 WC Materials Science, Composites SC Materials Science GA 047RR UT WOS:000311859400022 ER PT J AU Rahman, MM Zainuddin, S Hosur, MV Robertson, CJ Kumar, A Trovillion, J Jeelani, S AF Rahman, M. M. Zainuddin, S. Hosur, M. V. Robertson, C. J. Kumar, A. Trovillion, J. Jeelani, S. TI Effect of NH2-MWCNTs on crosslink density of epoxy matrix and ILSS properties of e-glass/epoxy composites SO COMPOSITE STRUCTURES LA English DT Article DE Functionalized MWCNTs; Crosslink density; Interlaminar shear strength; Calendaring; Sonication ID FUNCTIONALIZED CARBON NANOTUBES; FIBER-REINFORCED COMPOSITES; INTERLAMINAR SHEAR-STRENGTH; ELECTRICAL-PROPERTIES; DISPERSION; NANOCOMPOSITES AB Crosslink density is one of the important parameters that govern the physical properties of fiber reinforced polymer (FRP) composites. Enhancement of crosslink density by effective matrix modification through nanoparticle incorporation is the most prominent way to improve mechanical and thermo-mechanical properties of FRP composites. In this study, at first, 0.1-0.4 wt.% amino-functionalized multi-walled carbon nanotubes (NH2-MWCNTs) were incorporated in SC-15 epoxy system and the variation in crosslink density was investigated using rubber elasticity theory. Subsequently, the effect of these MWCNTs on interlaminar shear strength (ILSS) of e-glass/epoxy composites was studied. Result obtained from the tests showed a linearly increasing trend in crosslink density and ILSS properties from 0 to 0.3 wt.% MWCNTs loading. Better dispersion of MWCNTs facilitated more crosslinking sites, whereas, the three-way reaction between amine functional groups of MWCNTs with epoxide groups of resin and epoxy silanes of fiber surfaces improved the crosslinking and thereby ILSS properties of e-glass/epoxy composites. (c) 2012 Elsevier Ltd. All rights reserved. C1 [Zainuddin, S.; Hosur, M. V.; Jeelani, S.] Tuskegee Univ, Dept Mat Sci & Engn, Tuskegee, AL 36088 USA. [Rahman, M. M.; Robertson, C. J.; Jeelani, S.] Tuskegee Univ, Dept Mech Engn, Tuskegee, AL 36088 USA. [Kumar, A.; Trovillion, J.] USA, Construct Engn Res Lab, Engn Res & Dev Ctr, Champaign, IL 61821 USA. RP Zainuddin, S (reprint author), Tuskegee Univ, Dept Mat Sci & Engn, Tuskegee, AL 36088 USA. EM szainuddin@mytu.tuskegee.edu FU ERDC-CERL; NSF-EPSCoR FX The authors would like to acknowledge ERDC-CERL and NSF-EPSCoR for funding this work. NR 22 TC 19 Z9 20 U1 3 U2 64 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0263-8223 J9 COMPOS STRUCT JI Compos. Struct. PD JAN PY 2013 VL 95 BP 213 EP 221 DI 10.1016/j.compstruct.2012.07.019 PG 9 WC Materials Science, Composites SC Materials Science GA 047RR UT WOS:000311859400024 ER PT J AU Imae, N Taylor, S Iwata, N AF Imae, Naoya Taylor, Susan Iwata, Naoyoshi TI Micrometeorite precursors: Clues from the mineralogy and petrology of their relict minerals SO GEOCHIMICA ET COSMOCHIMICA ACTA LA English DT Article ID INTERPLANETARY DUST PARTICLES; ANTARCTIC MICROMETEORITES; COSMIC SPHERULES; ORDINARY CHONDRITES; CARBONACEOUS CHONDRITES; ORTHO-PYROXENE; ICE; COLLECTION; CHONDRULES; GREENLAND AB We analyzed 91 relict grain-bearing micrometeorites (MMs) from two Antarctic collections: Tottuki icefield and the South Pole Water Well. To determine if the MMs are related to specific meteorite groups, we analyzed their relict olivines and low-Ca pyroxenes and compared them with olivines and pyroxenes we analyzed in various meteorites: an enstatite chondrite (EH3), a suite of carbonaceous chondrites (CM2, CR2, CV3.2, CO3.0, and CO3.2), an ungrouped carbonaceous chondrite (Tagish Lake), various unequilibrated ordinary chondrites (H3.2, L3.7, LL3.0, LL3.2, LL3.3), and a Rumuruti chondrite (R3.5/5 breccia). Mg-rich olivines are the most common relict mineral in the MMs studied (42%), followed by Fe-rich olivines (16%), Mg-rich low-Ca pyroxenes (15%), and MMs containing both Mg-rich olivine and low-Ca pyroxene (13%). If one corrects for the effects of atmospheric heating on the proportion of olivines and pyroxenes, then 59% of MMs are related to carbonaceous chondrites, 22% to ordinary chondrites (mostly unequilibrated, UOCs), and 19% to a high-Mn group. Results of textural observations suggest that four MMs resemble chondrules from CO3 carbonaceous chondrites, and one is a shock-melted H chondrite. MMs from the high-Mn group appear to have crystallized from a melt and might be fragments of chondrule-like objects similar to those found in comet 81P/Wild 2. (C) 2012 Elsevier Ltd. All rights reserved. C1 [Imae, Naoya] Natl Inst Polar Res, Antarctic Meteorite Res Ctr, Tachikawa, Tokyo 1908518, Japan. [Imae, Naoya] Grad Univ Adv Studies, Dept Polar Sci, Sch Multidisciplinary Sci, Tachikawa, Tokyo 1908518, Japan. [Taylor, Susan] USA, Cold Reg Res & Engn Lab, Hanover, NH 03755 USA. [Iwata, Naoyoshi] Yamagata Univ, Dept Earth & Environm Sci, Yamagata 9908560, Japan. RP Imae, N (reprint author), Natl Inst Polar Res, Antarctic Meteorite Res Ctr, 10-3 Midori Cho, Tachikawa, Tokyo 1908518, Japan. EM imae@nipr.ac.jp RI Iwata, Naoyoshi/B-7554-2008 OI Iwata, Naoyoshi/0000-0002-0017-9130 FU Graduate University of Advanced Studies in Japan; NIPR publication subsidy FX We are grateful to Drs. C. Engrand, J. Duprat, E. Dobrica, and M. Maurette in C.S.N.S.M. in Orsay for their fruitful discussions, and also to Dr. Pichon for the use of SEM-EDS, and F. Couffignal for the use of EPMA during the stay of N.I. in France. Our appreciations are also extended to Dr. M. Funaki of NIPR for supplying a potted butt of the Tagish Lake carbonaceous chondrite, Dr. M. Zolensky for the PTS of the PRE 95404 Rumuruti chondrite, Smithsonian Institution for the polished thin sections of Kainsaz and Semarkona, and T. Niihara for supplying a BSE image of Y-791088. Dr. Miyake identified an amorphous silica and forsterite in TT001c3-A, and is acknowledged for discussion on low-Ca pyroxene phases. We are also grateful to the associate editor, Dr. A. N. Krot, the referees, Dr. C. Engrand and an anonymous reviewer for reviewing the manuscript. This research is partially supported as visiting research in C.S.N.S.M. by the Graduate University of Advanced Studies in Japan. The production of this paper was supported by an NIPR publication subsidy. NR 60 TC 2 Z9 2 U1 1 U2 17 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0016-7037 J9 GEOCHIM COSMOCHIM AC JI Geochim. Cosmochim. Acta PD JAN 1 PY 2013 VL 100 BP 116 EP 157 DI 10.1016/j.gca.2012.09.052 PG 42 WC Geochemistry & Geophysics SC Geochemistry & Geophysics GA 051CM UT WOS:000312102100008 ER PT J AU Okulicz, JF Yun, HC Murray, CK AF Okulicz, Jason F. Yun, Heather C. Murray, Clinton K. TI Occupational Exposures and the Prevalence of Blood-Borne Pathogens in a Deployed Setting: Data from a US Military Trauma Center in Afghanistan SO INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY LA English DT Article ID HEALTH-CARE WORKERS; HEPATITIS-B; OPERATING-ROOM; INFECTION; HIV; SYPHILIS; CONTACT; FLUIDS; KABUL AB OBJECTIVE. Occupational exposures to blood and other bodily fluids occur in approximately 5 per 100 persons every year in US hospitals. Since the provision of health care in the deployed environment poses unique challenges to hospital personnel, it is important to characterize the rates of occupational exposures and understand the prevalence of blood-borne pathogens (BBPs) in host nations. METHODS. A retrospective review of public health and laboratory records at a US military trauma center in Afghanistan from October 1, 2010, to March 31, 2012. RESULTS. A total of 65 occupational exposures were reported, including 47 (72%) percutaneous and 18 (28%) mucocutaneous, with a yearly rate of 8.6 exposures per 100 persons. During 6-month deployment cycles, the majority of exposures (46.2%) occurred in the first 2 months after arrival in Afghanistan. Physicians reported the most exposures (26%), and the operating room (48%) was the most common hospital location. The prevalence of hepatitis B and hepatitis C among local national source patients (n = 59) was 8.9% and 2.3%, respectively, with no cases of HIV or syphilis detected. In contrast, there were no BBPs detected in coalition source (n = 12) or exposed (n = 57) patients. CONCLUSIONS. The characteristics of occupational exposures in this deployed environment were comparable to those of US-based hospitals. Standard practices used to reduce occupational exposures, such as use of personal protective equipment and safety devices, should continue to be prioritized in the deployed setting. Although BBP rates are not well defined in Afghanistan, our results were consistent with those of prior epidemiologic studies. Infect Control Hosp Epidemiol 2013;34(1):74-79 C1 [Okulicz, Jason F.; Yun, Heather C.; Murray, Clinton K.] San Antonio Mil Med Ctr, Infect Dis Serv, San Antonio, TX USA. RP Okulicz, JF (reprint author), Brooke Army Med Ctr, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA. EM jason.okulicz@us.af.mil NR 27 TC 0 Z9 1 U1 0 U2 4 PU UNIV CHICAGO PRESS PI CHICAGO PA 1427 E 60TH ST, CHICAGO, IL 60637-2954 USA SN 0899-823X J9 INFECT CONT HOSP EP JI Infect. Control Hosp. Epidemiol. PD JAN PY 2013 VL 34 IS 1 BP 74 EP 79 DI 10.1086/668784 PG 6 WC Public, Environmental & Occupational Health; Infectious Diseases SC Public, Environmental & Occupational Health; Infectious Diseases GA 049YC UT WOS:000312018300011 PM 23221196 ER PT J AU Hong, SK Epureanu, BI Castanier, MP AF Hong, Sung-Kwon Epureanu, Bogdan I. Castanier, Matthew P. TI Robust signal processing for damaged vehicles with variability SO INTERNATIONAL JOURNAL OF VEHICLE DESIGN LA English DT Article DE robust signal processing; variabilities; PROMs; parametric reduced order models; effective independence distribution vector; bilinear mode shapes ID DYNAMIC ANALYSIS; BEAM AB The focus of this paper is on establishing a robust signal processing approach for damaged vehicles (i.e., cracked structures) with structural variability such as thicknesses of various components and Young's modulus variations. The approach assumes that vibration-type data is collected during the operation of a vehicle. Next, the collected data is used in a novel combined sensor selection and signal processing methodology. The new methodology resolves two key issues for complex structures with variability: (i) decides which field data channels are statistically optimal to be used, and (ii) establishes which data channels should correlate and how. The overall algorithm is based on a generalised version of the effective independence distribution vector. Also, the correlations among channels are used for noise rejection. Furthermore, the dynamics of the vehicle (i. e., a complex structure with variabilities) is modelled using Parametric Reduced Order Models (PROMs) and the concept of bilinear mode shapes introduced recently by the authors for cracked structures. PROMs are used to address the presence of variability and account for their effects on the data collected from various channels. The bilinear modes are used to capture the effects of the crack. The proposed methodology is demonstrated for a complex/realistic model of a HMMWV frame with parameter variability and a crack. C1 [Hong, Sung-Kwon; Epureanu, Bogdan I.] Univ Michigan, Dept Mech Engn, Ann Arbor, MI 48109 USA. [Castanier, Matthew P.] USA, Tank Automot Res Dev & Engn Ctr, Warren, MI 48397 USA. RP Epureanu, BI (reprint author), Univ Michigan, Dept Mech Engn, 2350 Hayward St, Ann Arbor, MI 48109 USA. EM sungkwon@umich.edu; epureanu@umich.edu; matt.castanier@us.army.mil OI Castanier, Matthew/0000-0002-3646-382X NR 23 TC 0 Z9 0 U1 1 U2 8 PU INDERSCIENCE ENTERPRISES LTD PI GENEVA PA WORLD TRADE CENTER BLDG, 29 ROUTE DE PRE-BOIS, CASE POSTALE 856, CH-1215 GENEVA, SWITZERLAND SN 0143-3369 J9 INT J VEHICLE DES JI Int. J. Veh. Des. PY 2013 VL 61 IS 1-4 BP 27 EP 46 DI 10.1504/IJVD.2013.050838 PG 20 WC Engineering, Mechanical; Transportation Science & Technology SC Engineering; Transportation GA 049RX UT WOS:000312002200002 ER PT J AU Ersal, T Gillespie, RB Brudnak, MJ Stein, JL Fathy, HK AF Ersal, Tulga Gillespie, R. Brent Brudnak, Mark J. Stein, Jeffrey L. Fathy, Hosam K. TI Effect of coupling point selection on distortion in internet-distributed hardware-in-the-loop simulation SO INTERNATIONAL JOURNAL OF VEHICLE DESIGN LA English DT Article DE coupling points; Internet-distributed hardware-in-the-loop simulation; ID-HILS; delay systems; distortion ID BILATERAL TELEOPERATION; DELAY COMPENSATION; STABILITY ANALYSIS; TIME-DELAY; SYSTEM; TELEMANIPULATION; PERFORMANCE; DYNAMICS; VEHICLE; MODEL AB The degree to which an Internet-Distributed Hardware-In-the-Loop (ID-HIL) simulation loses fidelity relative to the single-location alternative is referred to as distortion. This paper shows that, besides delay, the choice of coupling point, i.e., the port at which the system model is integrated across the Internet, also affects distortion. To quantify distortion, a frequency-domain metric is proposed using a linear systems framework. This metric is then used to analyse how the choice of coupling point affects distortion, leading to guidelines for selecting a coupling point that gives minimal distortion. The theory is demonstrated on a quarter-car model. C1 [Fathy, Hosam K.] Penn State Univ, University Pk, PA 16802 USA. [Ersal, Tulga; Gillespie, R. Brent; Stein, Jeffrey L.] Univ Michigan, Dept Mech Engn, Ann Arbor, MI 48109 USA. [Brudnak, Mark J.] USA, TARDEC, Res Dev & Engn Command RDECOM, Warren, MI USA. RP Fathy, HK (reprint author), Penn State Univ, 157D Hammond Bldg, University Pk, PA 16802 USA. EM tersal@umich.edu; brentg@umich.edu; mark.j.brudnak.civ@mail.mil; stein@umich.edu; hkf2@psu.edu RI Ersal, Tulga/B-5169-2008; Gillespie, Brent/K-3431-2016 OI Ersal, Tulga/0000-0002-6811-8529; Gillespie, Brent/0000-0002-1051-0026 NR 45 TC 6 Z9 6 U1 0 U2 11 PU INDERSCIENCE ENTERPRISES LTD PI GENEVA PA WORLD TRADE CENTER BLDG, 29 ROUTE DE PRE-BOIS, CASE POSTALE 856, CH-1215 GENEVA, SWITZERLAND SN 0143-3369 J9 INT J VEHICLE DES JI Int. J. Veh. Des. PY 2013 VL 61 IS 1-4 BP 67 EP 85 DI 10.1504/IJVD.2013.050840 PG 19 WC Engineering, Mechanical; Transportation Science & Technology SC Engineering; Transportation GA 049RX UT WOS:000312002200004 ER PT J AU Lee, TK Kim, Y Rizzo, DM Filipi, ZS AF Lee, Tae-Kyung Kim, Youngki Rizzo, Denise M. Filipi, Zoran S. TI Battery power management in heavy-duty HEVs based on the estimated critical surface charge SO INTERNATIONAL JOURNAL OF VEHICLE DESIGN LA English DT Article DE lithium-ion battery; power management; CSC; critical surface charge; lithium-ion concentration; estimation; EKF; extended Kalman filter; HEV; hybrid electric vehicle ID HYBRID-ELECTRIC VEHICLES; INSERTION CELL AB This paper proposes a battery power management strategy using Critical Surface Charge (CSC) information estimated by Extended Kalman Filter (EKF) in real time. The insight from CSC characterisation is used to propose a novel approach for supervisory control design of a series Hybrid Electric Vehicle (HEV). The underlying phenomenon determining the battery allowable power limits is closely connected to the CSC. The estimated CSC is processed with a Finite Impulse Response (FIR) filter to smoothen short-term fluctuations and highlight longer-term trajectories. The battery allowable power limits are adjusted based on the filtered CSC information to prevent undesirable battery operations. C1 [Filipi, Zoran S.] Univ Michigan, Dept Mech Engn, WE Automot Lab 2031, Ann Arbor, MI 48109 USA. [Lee, Tae-Kyung; Kim, Youngki] Univ Michigan, Dept Mech Engn, WE Automot Lab 1020, Ann Arbor, MI 48109 USA. [Rizzo, Denise M.] USA, RDECOM TARDEC, Warren, MI 48397 USA. RP Filipi, ZS (reprint author), Univ Michigan, Dept Mech Engn, WE Automot Lab 2031, 1231 Beal Ave, Ann Arbor, MI 48109 USA. EM kteel@umich.edu; youngki@umich.edu; denise.kramer@us.army.mil; filipi@umich.edu FU Automotive Research Center (ARC), a US Army center of excellence in modelling and simulation of ground vehicles; TARDEC, Warren FX This work has been partially supported by the Automotive Research Center (ARC), a US Army center of excellence in modelling and simulation of ground vehicles funded by TARDEC, Warren. NR 23 TC 4 Z9 4 U1 1 U2 13 PU INDERSCIENCE ENTERPRISES LTD PI GENEVA PA WORLD TRADE CENTER BLDG, 29 ROUTE DE PRE-BOIS, CASE POSTALE 856, CH-1215 GENEVA, SWITZERLAND SN 0143-3369 J9 INT J VEHICLE DES JI Int. J. Veh. Des. PY 2013 VL 61 IS 1-4 BP 108 EP 127 DI 10.1504/IJVD.2013.050842 PG 20 WC Engineering, Mechanical; Transportation Science & Technology SC Engineering; Transportation GA 049RX UT WOS:000312002200006 ER PT J AU Dong, G Ma, ZD Hulbert, G Kikuchi, N Arepally, S Vunnam, M Lou, KA AF Dong, Guang Ma, Zheng-Dong Hulbert, Gregory Kikuchi, Noboru Arepally, Sudhakar Vunnam, Madan Lou, Ken-An TI An efficient optimal design methodology for non-linear multibody dynamics systems with application to vehicle occupant restraint systems SO INTERNATIONAL JOURNAL OF VEHICLE DESIGN LA English DT Article DE active devices; automotive vehicles; multibody dynamics; topology optimisation; restraint system; sensitivity analysis; vehicle safety ID OPTIMIZATION; STIFFNESS AB The need exists for robust and efficient optimal design methods for application to multibody systems, in which the components to be designed represent connections between large displacement, large rotation motions of the subsystems' bodies. One specific application is occupant restraint systems, such as the Gunner Restraint System (GRS), in which both the vehicle and the gunner can undergo large relative and absolute motions under extreme driving or external threat conditions. In addition, the restraint/connection components can have amplitude-dependent, time-dependent, and timing-dependent behaviour, such as an active belt retractor. Current optimisation methodologies are ill suited for this problem, suffering from infeasibility, lack of robustness, and/or high computational expense. This paper presents an extension of topology optimisation techniques to consider multibody dynamics systems and to treat a much more open design space, which can include passive, active, and reactive structures/devices. The objective is to obtain an optimally combined structural and material system, considering the best use of passive, active and reactive members. C1 [Dong, Guang; Ma, Zheng-Dong; Hulbert, Gregory; Kikuchi, Noboru] Univ Michigan, Dept Mech Engn, Ann Arbor, MI 48109 USA. [Arepally, Sudhakar; Vunnam, Madan] USA, CASSI Analyt, TARDEC, Warren, MI 48397 USA. [Lou, Ken-An] ArmorWorks Enterprises LLC, R&D Dept, Chandler, AZ 85226 USA. RP Ma, ZD (reprint author), Univ Michigan, Dept Mech Engn, Ann Arbor, MI 48109 USA. EM dongg@umich.edu; mazd@umich.edu; hulbert@umich.edu; kikuchi@umich.edu; sudhakar.arepally@us.army.mil; madanmohan.vunnam@us.army.mil; klou@armorworks.com FU Automotive Research Center, a US Army Center of Excellence at the University of Michigan FX This research was supported partially by the Automotive Research Center, a US Army Center of Excellence headquartered at the University of Michigan. This support is gratefully acknowledged. NR 18 TC 1 Z9 1 U1 1 U2 13 PU INDERSCIENCE ENTERPRISES LTD PI GENEVA PA WORLD TRADE CENTER BLDG, 29 ROUTE DE PRE-BOIS, CASE POSTALE 856, CH-1215 GENEVA, SWITZERLAND SN 0143-3369 J9 INT J VEHICLE DES JI Int. J. Veh. Des. PY 2013 VL 61 IS 1-4 BP 177 EP 203 DI 10.1504/IJVD.2013.050845 PG 27 WC Engineering, Mechanical; Transportation Science & Technology SC Engineering; Transportation GA 049RX UT WOS:000312002200009 ER PT J AU Hoffenson, S Arepally, S Kokkolaras, M Papalambros, PY AF Hoffenson, Steven Arepally, Sudhakar Kokkolaras, Michael Papalambros, Panos Y. TI Quantification of the design relationship between ground vehicle weight and occupant safety under blast loading SO INTERNATIONAL JOURNAL OF VEHICLE DESIGN LA English DT Article DE military ground vehicle design; occupant safety; blastworthiness; vertical drop tower; design optimisation AB Military ground vehicle design must consider the threat posed by underbody blasts to new vehicles and their occupants, while also accounting for weight reduction goals for improving fuel economy and mobility. A two-stage process is presented to model the blast event, using LS-DYNA for simulating vehicle response and MADYMO for the occupant's response. Issues including computational expense, objective function formulation and multi-objective seating system design optimisation are addressed in detail, and three different blastworthiness optimisation formulations are presented and evaluated. C1 [Hoffenson, Steven; Kokkolaras, Michael; Papalambros, Panos Y.] Univ Michigan, Dept Mech Engn, Ann Arbor, MI 48109 USA. [Arepally, Sudhakar] USA, Tank Automot Res Dev & Engn Ctr, Warren, MI 48092 USA. RP Hoffenson, S (reprint author), Univ Michigan, Dept Mech Engn, 2250 GG Brown Bldg,2350 Hayward St, Ann Arbor, MI 48109 USA. EM shoffens@umich.edu; sudhakar.arepally@us.army.mil; mk@umich.edu; pyp@umich.edu OI Hoffenson, Steven/0000-0002-2200-3638 FU Automotive Research Center (ARC), a US Army Center of Excellence in Modelling and Simulation of Ground Vehicles FX This work has been supported partially by the Automotive Research Center (ARC), a US Army Center of Excellence in Modelling and Simulation of Ground Vehicles led by the University of Michigan. Such support does not constitute an endorsement by the sponsor of the opinions expressed in this paper. NR 20 TC 0 Z9 0 U1 1 U2 6 PU INDERSCIENCE ENTERPRISES LTD PI GENEVA PA WORLD TRADE CENTER BLDG, 29 ROUTE DE PRE-BOIS, CASE POSTALE 856, CH-1215 GENEVA, SWITZERLAND SN 0143-3369 J9 INT J VEHICLE DES JI Int. J. Veh. Des. PY 2013 VL 61 IS 1-4 BP 204 EP 218 DI 10.1504/IJVD.2013.050846 PG 15 WC Engineering, Mechanical; Transportation Science & Technology SC Engineering; Transportation GA 049RX UT WOS:000312002200010 ER PT J AU Kokkolaras, M Hulbert, G Papalambros, P Mourelatos, Z Yang, RJ Brudnak, M Gorsich, D AF Kokkolaras, M. Hulbert, G. Papalambros, P. Mourelatos, Z. Yang, R. J. Brudnak, M. Gorsich, D. TI Towards a comprehensive framework for simulation-based design validation of vehicle systems SO INTERNATIONAL JOURNAL OF VEHICLE DESIGN LA English DT Article DE simulation; dynamic systems; validation metrics; probabilistic principal component analysis; Bayesian interval-based hypothesis testing; confidence quantification; sequential design optimisation and calibration-based validation ID COMPUTER-MODELS; CALIBRATION AB We present an overview of our most recent and ongoing research efforts to develop a comprehensive framework for simulation-based design validation of vehicle systems. Specifically, we present the three major building blocks of our framework: (1) the introduction of an appropriate validation metric for dealing with the multivariate functional data that are the output of dynamic vehicle systems; (2) the robust implementation of a Bayesian interval-based hypothesis testing technique for quantifying the confidence in simulation models used for design under uncertainty; (3) the development of a sequential design optimisation and calibration-based validation methodology that addresses the inadequacy of current validation practices in simulation-based design optimisation. We present a simple yet illustrative example and discuss the techniques being developed currently that will complete the proposed framework. C1 [Kokkolaras, M.; Hulbert, G.; Papalambros, P.] Univ Michigan, Dept Mech Engn, Ann Arbor, MI 48109 USA. [Mourelatos, Z.] Oakland Univ, Dept Mech Engn, Rochester, MI 48309 USA. [Yang, R. J.] Ford Motor Co, Dearborn, MI 48121 USA. [Brudnak, M.; Gorsich, D.] USA, Tank Automot Res & Dev Engn Ctr, Warren, MI 48397 USA. RP Kokkolaras, M (reprint author), Univ Michigan, Dept Mech Engn, Ann Arbor, MI 48109 USA. EM mk@umich.edu; hulbert@umich.edu; pyp@umich.edu; mourelat@oakland.edu; ryang@ford.com; mark.brudnak@us.army.mil; david.gorsich@us.army.mil FU Ford Motor Company; Automotive Research Center (ARC), a US Army Center of Excellence in Modelling and Simulation of Ground Vehicles FX This work has been supported partially by Ford Motor Company and by the Automotive Research Center (ARC), a US Army Center of Excellence in Modelling and Simulation of Ground Vehicles led by the University of Michigan. Such support does not constitute an endorsement by the sponsors of the opinions expressed in this paper. NR 24 TC 0 Z9 0 U1 2 U2 5 PU INDERSCIENCE ENTERPRISES LTD PI GENEVA PA WORLD TRADE CENTER BLDG, 29 ROUTE DE PRE-BOIS, CASE POSTALE 856, CH-1215 GENEVA, SWITZERLAND SN 0143-3369 J9 INT J VEHICLE DES JI Int. J. Veh. Des. PY 2013 VL 61 IS 1-4 BP 233 EP 248 DI 10.1504/IJVD.2013.050847 PG 16 WC Engineering, Mechanical; Transportation Science & Technology SC Engineering; Transportation GA 049RX UT WOS:000312002200012 ER PT J AU Lucca, JJD Li, YS Simovic, MO Slack, JL Cap, A Falabella, MJ Dubick, M Lebeda, F Tsokos, GC AF Lucca, Jurandir J. Dalle Li, Yansong Simovic, Milomir O. Slack, Jessica L. Cap, Andrew Falabella, Michael J. Dubick, Michael Lebeda, Frank Tsokos, George C. TI Decay-accelerating factor limits hemorrhage-instigated tissue injury and improves resuscitation clinical parameters SO JOURNAL OF SURGICAL RESEARCH LA English DT Article DE Decay-accelerating factor; Complement; Hextend; Hemorrhagic shock ID MULTIPLE ORGAN FAILURE; FLUID RESUSCITATION; T-CELLS; COMPLEMENT; ISCHEMIA; ACTIVATION; PATHWAY; DAMAGE; PATHOPHYSIOLOGY; DYSFUNCTION AB Background: Complement is invariably activated during trauma and contributes to tissue injury. Recombinant human decay-accelerating factor (DAF), a complement regulatory protein that inhibits both classical and alternative pathways, improves survival and reduces tissue damage in animal models of tissue injury. The extent to which DAF may facilitate resuscitation in hemorrhaged large animals is not known. Methods: Male Yorkshire swine assigned to one of six groups were subjected to controlled, isobaric hemorrhage over 15 min to a target mean arterial pressure (MAP) of 35 mm Hg. Hypotension was maintained for 20 min followed by a bolus intravenous injection of DAF or vehicle followed by Hextend resuscitation. Animals were observed for 3 h after hypotensive Hextend resuscitation. Survival, blood chemistry, and physiological parameters were recorded. Additionally, tissue from lung, small intestine, liver, and kidney were subjected to histopathologic evaluation and tissue deposition of complement proteins was determined by immunohistochemistry, dot-blot, and Western blot analyses. Results: Administration of DAF (25 mu g/kg) to animals subjected to hemorrhage prior to Hextend infusion significantly improved survival (73% versus 27%); protected gut, lung, liver, and kidney tissue from damage; and resulted in reduced resuscitation fluid requirements when compared with animals subjected to hemorrhage and resuscitation with Hextend alone. Animals treated with a higher dose of DAF (50 mu g/kg) followed by Hextend fluid resuscitation did not experience the same benefit, suggesting a narrow therapeutic range for use of DAF as adjunct to Hextend fluid. Conclusion: DAF improved survival and reduced early Hextend fluid resuscitation requirements in swine subjected to hemorrhagic shock. These benefits are attributed to decreased complement deposition and limited organ damage. Published by Elsevier Inc. C1 [Lucca, Jurandir J. Dalle; Li, Yansong; Simovic, Milomir O.; Slack, Jessica L.; Cap, Andrew; Falabella, Michael J.; Dubick, Michael] USA, Immunomodulat Trauma Program, Inst Surg Res, San Antonio, TX USA. [Tsokos, George C.] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Med, Boston, MA 02215 USA. [Lebeda, Frank] USA, Med Res Mat Command, Combat Casualty Care Res Program, Ft Detrick, MD USA. RP Lucca, JJD (reprint author), USA, Inst Surg Res, 3650 Chambers Pass,BHT2 Bldg 3610, Ft Sam Houston, TX 78234 USA. EM jurandir.dallelucca@us.army.mil NR 32 TC 4 Z9 4 U1 0 U2 2 PU ACADEMIC PRESS INC ELSEVIER SCIENCE PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA SN 0022-4804 J9 J SURG RES JI J. Surg. Res. PD JAN PY 2013 VL 179 IS 1 BP 153 EP 167 DI 10.1016/j.jss.2012.10.017 PG 15 WC Surgery SC Surgery GA 051LW UT WOS:000312129700060 ER PT J AU Atkins, JL Barrows, E Byzek, SA Lee, CH Keesee, J Edwards, A Oliver, JD AF Atkins, James L. Barrows, Elizabeth Byzek, Stephen A. Lee, Chae-Hyuk Keesee, Jeffrey Edwards, Andrea Oliver, James D., III TI Regional citrate anticoagulation for hemorrhage experiments in rats SO JOURNAL OF SURGICAL RESEARCH LA English DT Article DE Hemorrhagic shock; Heparin; Citrate; Regional anticoagulation; Catheter ID THROMBIN GENERATION; TRAUMA-HEMORRHAGE; BLOOD-LOSS; SHOCK; RESUSCITATION; HEPARIN; HYPERCOAGULABILITY; COAGULOPATHY; SWINE; PREHEPARINIZATION AB Introduction: Hemorrhage alone without concomitant trauma often results in a hypercoagulable state that makes it difficult to prevent clotting within the blood withdrawal catheters. Although systemic administration of heparin can ameliorate this problem, heparin use has many additional actions that may confound interpretation of the hemorrhage experiments. The problem can be resolved by the use of a dual lumen catheter that anti-coagulates only the blood within the withdrawal circuit. We describe the design of such a catheter and evaluate its function in studies of hemorrhagic shock in rats. Materials and methods: Construction directions are provided for the dual lumen catheter along with a commercial source. The catheters were connected to computer controllable infusion syringes. Either citrate or heparin was used for regional extracorporeal anticoagulation. Rats were anesthetized and hemorrhaged to 40 mm Hg for more than 15 min through the use of a computer program written in Labview. Ionized calcium measurements were obtained pre- and posthemorrhage. Results: The catheters remained patent throughout the experiments. There was no significant difference in the ionized calcium whether citrate or heparin was used for extracorporeal anticoagulation. Conclusion: The dual lumen catheters are suitable for the study of hemorrhagic shock in rats without the need for systemic anticoagulation. The catheters can be used with computer-controlled hemorrhage procedures. (C) 2013 Elsevier Inc. All rights reserved. C1 [Atkins, James L.; Barrows, Elizabeth; Byzek, Stephen A.; Lee, Chae-Hyuk; Keesee, Jeffrey; Edwards, Andrea; Oliver, James D., III] Walter Reed Army Inst Res, Silver Spring, MD 20910 USA. RP Atkins, JL (reprint author), Uniformed Serv Univ Hlth Sci, Dept Med, Div Nephrol, 4301 Jones Bridge Rd, Bethesda, MD 20814 USA. EM Jim.atkins@us.army.mil NR 35 TC 0 Z9 0 U1 1 U2 3 PU ACADEMIC PRESS INC ELSEVIER SCIENCE PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA SN 0022-4804 J9 J SURG RES JI J. Surg. Res. PD JAN PY 2013 VL 179 IS 1 BP E197 EP E202 DI 10.1016/j.jss.2012.02.019 PG 6 WC Surgery SC Surgery GA 051LW UT WOS:000312129700025 PM 22504133 ER PT S AU Cho, JH Chen, IR Wang, Y Chan, KS AF Cho, Jin-Hee Chen, Ing-Ray Wang, Yating Chan, Kevin S. GP IEEE TI Trust-based Multi-Objective Optimization for Node-to-Task Assignment in Coalition Networks SO 2013 19TH IEEE INTERNATIONAL CONFERENCE ON PARALLEL AND DISTRIBUTED SYSTEMS (ICPADS 2013) SE International Conference on Parallel and Distributed Systems - Proceedings LA English DT Proceedings Paper CT 19th IEEE International Conference on Parallel and Distributed Systems (ICPADS) CY DEC 15-18, 2013 CL Seoul, SOUTH KOREA SP IEEE, IEEE Comp Soc, Tech Comm Distributed Proc, Tech Comm Parallel Proc, Korean Inst Informat Scientists & Engineers, Intel, HP, Nvidia, Samsung, Postech, Ctr Mobile Embedded Software Technol, ManyCoreSoft DE multi-objective optimization; task assignment; trust; risk ID MANAGEMENT AB A temporary coalition is often formed to pursue a common goal based on the collaboration of multiple partners who may have their own objectives. The coalition network must attain multiple objectives, under resource constraints and time deadlines. We propose a task assignment algorithm for a scenario where tasks are dynamic, with different arrival times and deadlines. We propose a heuristic coalition formation technique that uses multiple dimensions of trust (i.e., integrity, competence, social connectedness, and reciprocity) to assess trust of each entity. The proposed scheme enables task leaders to make critical assignment decisions based on assessed trustworthiness of entities. We consider three different objectives, namely, maximizing resilience and resource utilization while minimizing delay to task completion. We devise a ranking-based heuristic with linear runtime complexity to select members based on risk derived from trust assessment of nodes. We validate the performance of our proposed scheme by comparing our scheme with a non-trust-based baseline scheme as well as a global optimal solution implemented with the Integer Linear Programming technique. C1 [Cho, Jin-Hee; Chan, Kevin S.] US Army Res Lab, Computat & Informat Sci Directorate, Washington, DC USA. [Chen, Ing-Ray; Wang, Yating] Virginia Tech, Dept Comp Sci, Blacksburg, VA 24061 USA. RP Cho, JH (reprint author), US Army Res Lab, Computat & Informat Sci Directorate, Washington, DC USA. EM jinhee.cho@us.army.mil; irchen@vt.edu; yatingw@vt.edu; kevin.s.chan@us.army.mil NR 18 TC 1 Z9 1 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1521-9097 BN 978-1-4799-2081-5 J9 INT C PAR DISTRIB SY PY 2013 BP 372 EP 379 DI 10.1109/ICPADS.2013.59 PG 8 WC Computer Science, Hardware & Architecture SC Computer Science GA BC7XT UT WOS:000355315600042 ER PT S AU Dao, M Nguyen, L Tran, TD AF Dao, Minh Lam Nguyen Tran, Trac D. GP IEEE TI TEMPORAL RATE UP-CONVERSION OF SYNTHETIC APERTURE RADAR VIA LOW-RANK MATRIX RECOVERY SO 2013 20TH IEEE INTERNATIONAL CONFERENCE ON IMAGE PROCESSING (ICIP 2013) SE IEEE International Conference on Image Processing ICIP LA English DT Proceedings Paper CT 20th IEEE International Conference on Image Processing (ICIP) CY SEP 15-18, 2013 CL Melbourne, AUSTRALIA SP Inst Elect & Elect Engineers, IEEE Signal Proc Soc DE Synthetic aperture radar (SAR); rate up-conversion; low-rank matrix completion; robust PCA AB The radar data to form synthetic aperture radar (SAR) imagery is normally transmitted and received by moving platforms like aircraft or vehicles. In many situations, the platforms move at high speed; which reduces the number of sampling records collected to the synthetic aperture, hence degrades the quality of the reconstructed SAR images. Therefore, it is necessary to develop an algorithm that is capable of increasing the temporal frequency rate of the received data. In this paper, we propose a novel technique to generate intermediate records from the existing ones by a locally-adaptive low-rank matrix recovery framework. The system first fills in the blank records using a bi-directional motion estimation scheme. The initialized aperture records are then refined by a robust low-rank matrix completion algorithm using the reference from neighborhood clean records. Experiments demonstrate that the proposed method provides comparative results when up-converting the aperture rate by a factor of two or four, both in mean square error of the raw SAR signal and PSNR performance of the recovered SAR images. C1 [Dao, Minh; Tran, Trac D.] Johns Hopkins Univ, Dept Elect & Comp Engn, Baltimore, MD 21218 USA. [Lam Nguyen] US Army, Res Lab, Adelphi, MD 20783 USA. RP Dao, M (reprint author), Johns Hopkins Univ, Dept Elect & Comp Engn, Baltimore, MD 21218 USA. NR 9 TC 3 Z9 3 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1522-4880 BN 978-1-4799-2341-0 J9 IEEE IMAGE PROC PY 2013 BP 2358 EP 2362 PG 5 WC Imaging Science & Photographic Technology SC Imaging Science & Photographic Technology GA BC3FD UT WOS:000351597602095 ER PT J AU Yang, JJ Zhou, W Chang-Hasnain, C Lalanne, P AF Yang, Jianji Zhou, W. Chang-Hasnain, C. Lalanne, P. GP IEEE TI Slow-light in a Cage SO 2013 7TH INTERNATIONAL CONGRESS ON ADVANCED ELECTROMAGNETIC MATERIALS IN MICROWAVES AND OPTICS (METAMATERIALS 2013) LA English DT Proceedings Paper CT 7th International Congress on Advanced Electromagnetic Materials in Microwaves and Optics (METAMATERIALS) CY SEP 16-19, 2013 CL Bordeaux, FRANCE ID WAVE-GUIDES AB Slow-light effect has potential for applications ranging from optical information processing to optical switching. It is well-known that material dispersion can induce slow-light near some resonances, such as electromagnetically induced transparency. Additionally, structural dispersion can also be applied to realize slow-light, e.g. photonic crystal waveguides (PhCWs). Here we study the Bloch modes of a silicon periodic waveguide with an ultra-large hollow-core. With three-dimensional fully-vectorial calculations, we successively find that the proposed periodic waveguide can support guided Bloch modes (below the air light line). Moreover, this cage waveguide is quite flexible for geometric tailoring of dispersion relation, and can be a promising device for integrated nanophotonics. C1 [Yang, Jianji; Lalanne, P.] Univ Bordeaux 1, CNRS, Lab Photon Numer & Nanosci, Inst Opt, F-33405 Talence, France. [Zhou, W.] US Army, Res Lab, Adelphi, MD 20783 USA. [Chang-Hasnain, C.] Univ Calif Berkeley, Dept Elect Engn & Comp Sci, Berkeley, CA 94720 USA. RP Yang, JJ (reprint author), Univ Bordeaux 1, CNRS, Lab Photon Numer & Nanosci, Inst Opt, F-33405 Talence, France. EM jianji.yang@institutoptique.fr NR 11 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-1232-2 PY 2013 BP 319 EP 321 PG 3 WC Engineering, Electrical & Electronic; Optics; Physics, Applied SC Engineering; Optics; Physics GA BC3WE UT WOS:000352010200107 ER PT J AU Chen, IR Guo, J Bao, FY Cho, JH AF Chen, Ing-Ray Guo, Jia Bao, Fenye Cho, Jin-Hee GP IEEE TI Integrated Social and Quality of Service Trust Management of Mobile Groups in Ad Hoc Networks SO 2013 9TH INTERNATIONAL CONFERENCE ON INFORMATION, COMMUNICATIONS AND SIGNAL PROCESSING (ICICS) LA English DT Proceedings Paper CT 9th International Conference on Information, Communications and Signal Processing (ICICS) CY NOV 10-13, 2013 CL Tainan, TAIWAN SP Nanyang Technolog Univ, Sch Elect & Elect Engn, Natl Cheng Kung Univ, Dept Elect Engn, IEEE Tainan Sect, IEEE Circuits & Syst Soc, Tainan Chapter, IEEE Computat Intelligence Soc, Tainan Chapter, IEEE Commun Soc, Singapore Chapter, IEEE Commun Soc, Tainan Chapter, IEEE Signal Proc Soc, Singapore Chapter, IEEE Signal Proc Soc, Tainan Chapter DE trust management; mobile ad hoc networks; QoS trust; social trust; trust bias minimization ID ADMISSION CONTROL; MULTIMEDIA SERVERS; OPTIMIZATION; WIRELESS AB We propose to combine social trust derived from social networks with quality-of-service (QoS) trust derived from communication networks to obtain a composite trust metric as a basis for evaluating trust of mobile nodes in mobile ad hoc network (MANET) environments. We develop a novel model-based approach to identify the best protocol setting under which trust bias is minimized, that is, the peer-to-peer subjective trust as a result of executing our distributed trust management protocol is close to ground truth status over a wide range of operational and environment conditions with high resiliency to malicious attacks and misbehaving nodes. C1 [Chen, Ing-Ray; Guo, Jia; Bao, Fenye] Virginia Tech, Dept Comp Sci, Blacksburg, VA 24061 USA. [Cho, Jin-Hee] US Army, Res Lab, Washington, DC USA. RP Chen, IR (reprint author), Virginia Tech, Dept Comp Sci, Blacksburg, VA 24061 USA. EM irchen@vt.edu; jiaguo@vt.edu; baofenye@vt.edu; jinhee.cho@us.army.mil NR 18 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4799-0434-1 PY 2013 PG 5 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BC5JU UT WOS:000353339000178 ER PT S AU Barry, BE Meyer, KF Arnett, KP Spittka, B AF Barry, Brock E. Meyer, Karl F. Arnett, Kevin P. Spittka, Berndt GP ASEE TI Competition-Based Learning Activities within Civil Engineering Education: A Critical Review of Current Options SO 2013 ASEE ANNUAL CONFERENCE SE ASEE Annual Conference & Exposition LA English DT Proceedings Paper CT ASEE Annual Conference CY JUN 23-26, 2013 CL Atlanta, GA SP ASEE AB Structured, competition-based learning activities have been used in the process of educating aspiring civil engineers for many years. Some of the better known and more widely adopted intercollegiate competitions include the American Society of Civil Engineers' Concrete Canoe Competition and the American Society of Civil Engineers/American Institute for Steel Construction's National Steel Bridge Competition. Beyond these common competitions, it is estimated that upwards of 38 additional competitions, sponsored by various organizations, are in use to varying extents by civil engineering programs throughout the United States. Data collected during this study enabled a thorough investigation of national and regional civil engineering competitions. A detailed analysis of each identified competition has been performed by the investigation team. In addition, a survey of ABET, Inc. accredited civil engineering programs heads was performed to capture the frequency and distribution of individual competitions, as well as an assessment of the department heads' perceived educational value to the participants of each competition. An existing, well-established, and validated education metric has been used as the tool by which each competition is evaluated. Given the resource investment required to participate in many of the competitions currently in use, it is anticipated that the results of this study will be of interest to civil engineering program administrators, faculty members, sponsoring agencies associated with current competitions, and developers of future civil engineering competitions. C1 [Barry, Brock E.; Arnett, Kevin P.; Spittka, Berndt] US Mil Acad, Dept Civil & Mech Engn, West Point, NY 10996 USA. [Meyer, Karl F.] US Mil Acad, Dept Civil & Mech Engn, Civil Engn Div, West Point, NY 10996 USA. RP Barry, BE (reprint author), US Mil Acad, Dept Civil & Mech Engn, West Point, NY 10996 USA. NR 26 TC 0 Z9 0 U1 0 U2 1 PU AMER SOC ENGINEERING EDUCATION PI WASHINGTON PA 1818 N STREET, NW SUITE 600, WASHINGTON, DC 20036 USA SN 2153-5965 J9 ASEE ANNU CONF EXPO PY 2013 PG 15 WC Education & Educational Research; Education, Scientific Disciplines; Engineering, Multidisciplinary SC Education & Educational Research; Engineering GA BE0YQ UT WOS:000367454800035 ER PT S AU Benson, MJ Thomas, HJ Reed, SA Floersheim, B Condly, SJ AF Benson, Michael J. Thomas, Hans J. Reed, Shad A. Floersheim, Bruce Condly, Steven J. GP ASEE TI Leveraging Summer Immersive Experiences into ABET Curricula SO 2013 ASEE ANNUAL CONFERENCE SE ASEE Annual Conference & Exposition LA English DT Proceedings Paper CT ASEE Annual Conference CY JUN 23-26, 2013 CL Atlanta, GA SP ASEE AB Summer immersive experiences for undergraduate students in Aeronautical and Mechanical Engineering programs come in varied forms and can represent a substantial effort by staff and faculty, as well as considerable financial resources to coordinate. Experiences range from work in governmental laboratories and research centers to collaboration with industry partners, and may include graduate research at distant academic locations. This study seeks to evaluate the utility of these work experiences, measuring their effectiveness across ABET program outcomes and assessing their contribution to student learning and motivation to continue to learn. A survey of 53 students who conducted immersive experiences related to Aeronautical and Mechanical Engineering disciplines from the United States Air Force Academy and the United States Military Academy has been conducted. Survey results are analyzed to determine the overall value provided by the experience as measured across program outcomes outlined in ABET criteria 3 (a-k). The unique contributions available from the experience are balanced with the administrative requirements to suggest a best practice in leveraging the most from these experiences and to assist programs that might consider initiating or refining their own participation in similar programs. C1 [Benson, Michael J.; Thomas, Hans J.] US Mil Acad, West Point, NY 10996 USA. [Thomas, Hans J.] US Air Force Acad, Dept Aeronaut, Colorado Springs, CO 80840 USA. [Floersheim, Bruce] US Mil Acad, Dept Civil & Mech Engn, West Point, NY 10996 USA. [Condly, Steven J.] US Mil Acad, Off Inst Res, Taylor Hall 5th Floor, West Point, NY 10996 USA. RP Benson, MJ (reprint author), US Mil Acad, West Point, NY 10996 USA. EM scondly@gmail.com NR 24 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC ENGINEERING EDUCATION PI WASHINGTON PA 1818 N STREET, NW SUITE 600, WASHINGTON, DC 20036 USA SN 2153-5965 J9 ASEE ANNU CONF EXPO PY 2013 PG 15 WC Education & Educational Research; Education, Scientific Disciplines; Engineering, Multidisciplinary SC Education & Educational Research; Engineering GA BE0YQ UT WOS:000367454802052 ER PT S AU Crawford, G Byers, LK Zifchock, R AF Crawford, Grant Byers, Lynn K. Zifchock, Rebecca GP ASEE TI Computer Aided Design: Learning Style Preference Effect on Student Learning SO 2013 ASEE ANNUAL CONFERENCE SE ASEE Annual Conference & Exposition LA English DT Proceedings Paper CT ASEE Annual Conference CY JUN 23-26, 2013 CL Atlanta, GA SP ASEE AB In the Computer Aided Design ( CAD) course at the United States Military Academy ( West Point, NY), students learn two different design software packages, SolidWorks (TM) and MATLAB (TM). In the past, faculty members who are responsible for teaching the course have observed a difference in performance by the students in course homework assignments and examinations between the two applications. In general, students performed higher on SolidWorks assignments. This poses the question: Does learning style preference affect the ability to learn different computer aided design tools? One hundred and eleven students enrolled in either the Spring 2012 (n = 61) or Fall 2013 (n = 50) semesters of Computer-Aided Design were asked to participate in this Institutional Review Board exempted study. Each student was asked to take Felder's and Soloman's "Index of Learning Styles" questionnaire(1). Of the four learning dimensions that are evaluated in the questionnaire, only the scores for two, Visual versus Verbal and Sequential versus Global, were examined in this study. These two dimensions seem to be most relevant to the research question. We expected that SolidWorks was more suited to learners who tend to be more visually and globally-oriented. Conversely, we expected MATLAB to be more suited for more verbally and sequentially-oriented students. This paper discusses the results of our study. The raw data in the Visual/Verbal domain appear to support our hypothesis to suggest that verbal learners perform better in MATLAB programming than in SolidWorks modeling, whereas visual learners have a less distinct difference in performance. A survey of students also indicates that a higher percentage of verbal learners prefer MATLAB compared to their visual counterparts. C1 [Crawford, Grant] US Mil Acad, Mech Engn Program, West Point, NY 10996 USA. [Byers, Lynn K.] US Mil Acad, Mech Engn Program, Design Grp, West Point, NY 10996 USA. [Zifchock, Rebecca] US Mil Acad, West Point, NY 10996 USA. RP Crawford, G (reprint author), US Mil Acad, Mech Engn Program, West Point, NY 10996 USA. NR 2 TC 0 Z9 0 U1 1 U2 1 PU AMER SOC ENGINEERING EDUCATION PI WASHINGTON PA 1818 N STREET, NW SUITE 600, WASHINGTON, DC 20036 USA SN 2153-5965 J9 ASEE ANNU CONF EXPO PY 2013 PG 9 WC Education & Educational Research; Education, Scientific Disciplines; Engineering, Multidisciplinary SC Education & Educational Research; Engineering GA BE7HA UT WOS:000375255602031 ER PT S AU Goyings, MRR Klosky, JL Crawford, BG AF Goyings, Major Ryan R. Klosky, James Ledlie Crawford, Bobby G. GP ASEE TI iPads in the Engineering Classroom - Boon or Bane? SO 2013 ASEE ANNUAL CONFERENCE SE ASEE Annual Conference & Exposition LA English DT Proceedings Paper CT ASEE Annual Conference CY JUN 23-26, 2013 CL Atlanta, GA SP ASEE C1 [Goyings, Major Ryan R.] US Mil Acad, Civil & Mech Engn Dept, West Point, NY 10996 USA. [Klosky, James Ledlie; Crawford, Bobby G.] US Mil Acad, West Point, NY 10996 USA. RP Goyings, MRR (reprint author), US Mil Acad, Civil & Mech Engn Dept, West Point, NY 10996 USA. NR 5 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC ENGINEERING EDUCATION PI WASHINGTON PA 1818 N STREET, NW SUITE 600, WASHINGTON, DC 20036 USA SN 2153-5965 J9 ASEE ANNU CONF EXPO PY 2013 PG 18 WC Education & Educational Research; Education, Scientific Disciplines; Engineering, Multidisciplinary SC Education & Educational Research; Engineering GA BE7HB UT WOS:000375256303043 ER PT S AU Hart, SD Shockley, JC Ellis, LR Spittka, MB AF Hart, Steven D. Shockley, Johnette C. Ellis, Leah R. Spittka, Major Berndt GP ASEE TI The Goethals Infrastructure Challenge: A Proposal for a New Student Competition SO 2013 ASEE ANNUAL CONFERENCE SE ASEE Annual Conference & Exposition LA English DT Proceedings Paper CT ASEE Annual Conference CY JUN 23-26, 2013 CL Atlanta, GA SP ASEE AB The American Institute of Steel Construction (AISC) and American Society of Civil Engineers (ASCE) Steel Bridge and ASCE's Concrete Canoe competitions are a staple of civil engineering education. These two competitions provide a technical design problem for students to solve under very tight performance requirements, solution envelopes, and evaluation standards which tend to drive competitors to similar, optimized solutions. In contrast to these highly structured problems, both the National Academy of Engineering (NAE) and the American Society of Civil Engineers (ASCE) report that the engineer of the 21st Century will also be called upon to solve extremely complex, daunting, and ill-structured problems. The authors and their institutions are currently developing the Goethals Infrastructure Challenge as a new student competition built around solving the social-technical, complex adaptive, and 'wicked' problems associated with designing, constructing, operating and maintaining the world's infrastructure. This paper explains the organization of the Goethals Infrastructure Challenge, the student learning objectives for participating in the challenge, the annual process used to formulate the challenge, required funding mechanism, submission procedures, judging and evaluation plans, and budgeting and funding. In addition to being educational, this competition is designed to inspire a new generation of engineers to address the challenges we face in "restoring and improving urban infrastructure" and "providing access to clean water" as suggested by the NAE, managing the $2.2 trillion necessary to improve our infrastructure, and defining what infrastructure should be and do when functioning optimally in the knowledge-based, global economy of the 21st Century. For this reason, the challenge is named for George Washington Goethals who, with the building of the Panama Canal, transformed 20th Century infrastructure in the hope that this event will inspire the participants and the engineering profession to transform the 21st Century infrastructure in a similar way. C1 [Hart, Steven D.] US Mil Acad, West Point, PA 40006 USA. [Shockley, Johnette C.] US Army, Corps Engineers, Engineer Res & Dev Ctr, Washington, DC USA. [Ellis, Leah R.] Univ Nebraska, Peter Kiewit Inst, Lincoln, NE 68583 USA. [Spittka, Major Berndt] US Mil Acad, Dept Civil & Mech Engn, Washington, DC USA. RP Hart, SD (reprint author), US Mil Acad, West Point, PA 40006 USA. NR 21 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC ENGINEERING EDUCATION PI WASHINGTON PA 1818 N STREET, NW SUITE 600, WASHINGTON, DC 20036 USA SN 2153-5965 J9 ASEE ANNU CONF EXPO PY 2013 PG 14 WC Education & Educational Research; Education, Scientific Disciplines; Engineering, Multidisciplinary SC Education & Educational Research; Engineering GA BE0YQ UT WOS:000367454803027 ER PT S AU Heyman, MJL Huang, WL Xie, GM Taephanitcharoen, P AF Heyman, Major Joseph Lee Huang, Wenli Xie, Guangming Taephanitcharoen, Pongpat GP ASEE TI Increasing ECE Student Excitement through an International Marine Robotics Competition SO 2013 ASEE ANNUAL CONFERENCE SE ASEE Annual Conference & Exposition LA English DT Proceedings Paper CT ASEE Annual Conference CY JUN 23-26, 2013 CL Atlanta, GA SP ASEE C1 [Heyman, Major Joseph Lee; Huang, Wenli] US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. [Xie, Guangming] Peking Univ, Dept Mech & Engn Sci, Ctr Syst & Control, Beijing 100871, Peoples R China. [Taephanitcharoen, Pongpat] US Mil Acad, West Point, NY 10996 USA. RP Heyman, MJL (reprint author), US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. NR 14 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC ENGINEERING EDUCATION PI WASHINGTON PA 1818 N STREET, NW SUITE 600, WASHINGTON, DC 20036 USA SN 2153-5965 J9 ASEE ANNU CONF EXPO PY 2013 PG 12 WC Education & Educational Research; Education, Scientific Disciplines; Engineering, Multidisciplinary SC Education & Educational Research; Engineering GA BE7HB UT WOS:000375256303001 ER PT S AU Manous, JD Nelson, JD AF Manous, Joe D., Jr. Nelson, Jon D. GP ASEE TI Opportunities for Civil Engineering Technologists within the Enterprise of Civil Engineering SO 2013 ASEE ANNUAL CONFERENCE SE ASEE Annual Conference & Exposition LA English DT Proceedings Paper CT ASEE Annual Conference CY JUN 23-26, 2013 CL Atlanta, GA SP ASEE C1 [Manous, Joe D., Jr.] USACE, Inst Water Resources, Washington, DC 20314 USA. [Nelson, Jon D.] Tetra Tech Inc, Cent Reg Engn & Consulting Serv Grp, Tulsa, OK USA. RP Manous, JD (reprint author), USACE, Inst Water Resources, Washington, DC 20314 USA. NR 14 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC ENGINEERING EDUCATION PI WASHINGTON PA 1818 N STREET, NW SUITE 600, WASHINGTON, DC 20036 USA SN 2153-5965 J9 ASEE ANNU CONF EXPO PY 2013 PG 17 WC Education & Educational Research; Education, Scientific Disciplines; Engineering, Multidisciplinary SC Education & Educational Research; Engineering GA BE7HA UT WOS:000375255605010 ER PT S AU Pfluger, AR Baideme, MP Matthew, KE Lewandowski, SA Starke, JA Butkus, MA AF Pfluger, Andrew Ross Baideme, Matthew P. Matthew, Katie E. Lewandowski, Stephen A. Starke, Jeffrey Allan Butkus, Michael A. GP ASEE TI Interdisciplinary, real-world, client-based term projects in an introductory environmental engineering and science course SO 2013 ASEE ANNUAL CONFERENCE SE ASEE Annual Conference & Exposition LA English DT Proceedings Paper CT ASEE Annual Conference CY JUN 23-26, 2013 CL Atlanta, GA SP ASEE AB Many universities have real environmental problems in areas such as energy efficiency, water efficiency, and solid waste management, but do not always have the time or resources to examine the problems in depth. The United States Military Academy (USMA) employs an introductory environmental engineering and science course required for environmental engineering and environmental science majors, which is taken during the first semester of their junior year. Additionally, USMA requires that all non-engineering majors take a three-course engineering sequence, and a slightly modified version of the introductory course is taught each year to approximately 170 such students in the first semester of their junior year. Within the context of the course, we maintain a semester-long term project that examines real environmental problems, which our student teams (3-4 students of varying academic majors) observe or clients (such as the Department of Public Works or our student government) identify. Preparation for the project requires student teams to develop a hypothesis and a basic sampling and evaluation protocol. Students then use the protocol to conduct sampling in the local community and analyze results in light of their hypothesis. Students are required to submit a final written report. This term project model also encourages interdisciplinary collaboration with non-STEM disciplines, such as the Marketing course in USMA's Department of Behavioral Sciences and Leadership. This cross-cutting educational method can create more holistic solutions to the identified problems and enhance student learning. To date, assessment of students who participated in the real-world, client-based project versus a general environmental project indicated an improvement in several important areas: valuation of results, motivation and understanding, and confidence in problem solving skills. This work presents the methods our program developed to incorporate the scientific method, hypothesis development, and sampling methodologies to help solve these relevant real-world problems. The methods required to implement this educational experience in environmental engineering programs to meet ABET accreditation requirements are also discussed. C1 [Pfluger, Andrew Ross; Baideme, Matthew P.; Lewandowski, Stephen A.] US Mil Acad, Dept Geog & Environm Engn, West Point, NY 10996 USA. [Baideme, Matthew P.] US Mil Acad, Environm Sci & Environm Engn Technol, West Point, NY 10996 USA. [Matthew, Katie E.] US Army, West Point, NY USA. [Starke, Jeffrey Allan; Butkus, Michael A.] US Mil Acad, West Point, NY 10996 USA. RP Pfluger, AR (reprint author), US Mil Acad, Dept Geog & Environm Engn, West Point, NY 10996 USA. NR 14 TC 0 Z9 0 U1 2 U2 2 PU AMER SOC ENGINEERING EDUCATION PI WASHINGTON PA 1818 N STREET, NW SUITE 600, WASHINGTON, DC 20036 USA SN 2153-5965 J9 ASEE ANNU CONF EXPO PY 2013 PG 17 WC Education & Educational Research; Education, Scientific Disciplines; Engineering, Multidisciplinary SC Education & Educational Research; Engineering GA BE0YQ UT WOS:000367454805018 ER PT S AU Chen, G Drost, RJ Sadler, BM Liao, LC AF Chen, Gang Drost, Robert J. Sadler, Brian M. Liao, Linchao GP IEEE TI Long-Distance Ultraviolet Scattering Channel Measurements: Analog vs. Digital Approaches SO 2013 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO) SE Conference on Lasers and Electro-Optics LA English DT Proceedings Paper CT Conference on Lasers and Electro-Optics (CLEO) CY JUN 09-14, 2013 CL San Jose, CA AB We compare an analog and a digital method for characterizing the long-distance non-line-of-sight ultraviolet scattering channel. Experimental results and theoretical-model predictions are presented that provide demonstration and validation. (C) 2013 Optical Society of America C1 [Chen, Gang; Liao, Linchao] Univ Calif Riverside, Dept Elect Engn, Riverside, CA 92521 USA. [Drost, Robert J.; Sadler, Brian M.] Army Res Lab, Adelphi, MD 20783 USA. RP Chen, G (reprint author), Univ Calif Riverside, Dept Elect Engn, Riverside, CA 92521 USA. EM gachen@ee.ucr.edu NR 4 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2160-9020 BN 978-1-55752-973-2 J9 CONF LASER ELECTR PY 2013 PG 2 WC Engineering, Electrical & Electronic; Optics; Physics, Applied SC Engineering; Optics; Physics GA BC7WX UT WOS:000355262504123 ER PT S AU Connelly, BC Woodward, NT Metcalfe, GD Rodak, LE Das, NC Reed, ML Sampath, AV Shen, HE Wraback, M Farrell, RM Iza, M Cruz, SC Lang, JR Young, NG Terao, Y Neufeld, CJ Keller, S Nakamura, S DenBaars, SP Mishra, UK Speck, JS AF Connelly, Blair C. Woodward, Nathaniel T. Metcalfe, Grace D. Rodak, Lee E. Das, Naresh C. Reed, Meredith L. Sampath, Anand V. Shen, Hongen Wraback, Michael Farrell, Robert M. Iza, Michael Cruz, Samantha C. Lang, Jordan R. Young, Nathan G. Terao, Yutaka Neufeld, Carl J. Keller, Stacia Nakamura, Shuji DenBaars, Steven P. Mishra, Umesh K. Speck, James S. GP IEEE TI Study of Temperature-Dependent Carrier Transport in a p-GaN/i-InGaN/n-GaN Solar Cell Heterostructure using Ultrafast Spectroscopy SO 2013 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO) SE Conference on Lasers and Electro-Optics LA English DT Proceedings Paper CT Conference on Lasers and Electro-Optics (CLEO) CY JUN 09-14, 2013 CL San Jose, CA ID POLARIZATION AB Temperature-dependent carrier transport is investigated using ultrafast spectroscopy in a p-GaN/iInGaN/n-GaN solar cell with heavily-doped layers to compensate for polarization charges at the hetero-interface. We observe a flip in the transport direction at 110 K. C1 [Connelly, Blair C.; Woodward, Nathaniel T.; Metcalfe, Grace D.; Rodak, Lee E.; Das, Naresh C.; Reed, Meredith L.; Sampath, Anand V.; Shen, Hongen; Wraback, Michael] US Army, Res Lab, RDRL SEE M, Adelphi, MD 20783 USA. [Farrell, Robert M.; Iza, Michael; Cruz, Samantha C.; Lang, Jordan R.; Young, Nathan G.; Terao, Yutaka; Neufeld, Carl J.; Keller, Stacia; Nakamura, Shuji; DenBaars, Steven P.; Mishra, Umesh K.; Speck, James S.] Univ Calif Santa Barbara, Santa Barbara, CA 93106 USA. RP Connelly, BC (reprint author), US Army, Res Lab, RDRL SEE M, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. EM blair.connelly.ctr@mail.mil NR 8 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2160-9020 BN 978-1-55752-973-2 J9 CONF LASER ELECTR PY 2013 PG 2 WC Engineering, Electrical & Electronic; Optics; Physics, Applied SC Engineering; Optics; Physics GA BC7WX UT WOS:000355262502174 ER PT S AU Moe, CG Chen, JF Grandusky, JR Mendrick, MC Randive, R Rodak, LE Sampath, AV Wraback, M Schowalter, LJ AF Moe, Craig G. Chen, Jianfeng (Jeff) Grandusky, James R. Mendrick, Mark C. Randive, Rajul Rodak, Lee E. Sampath, Anand V. Wraback, Michael Schowalter, Leo J. GP IEEE TI Pseudomorphic Mid-Ultraviolet Light-Emitting Diodes for Water Purification SO 2013 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO) SE Conference on Lasers and Electro-Optics LA English DT Proceedings Paper CT Conference on Lasers and Electro-Optics (CLEO) CY JUN 09-14, 2013 CL San Jose, CA AB UVC light output of 66 mW at 300 mA CW has been achieved from LEDs on AlN substrates with extensive photon extraction. Proper vessel design allows for efficient irradiation of a water sample for purification. C1 [Moe, Craig G.; Chen, Jianfeng (Jeff); Grandusky, James R.; Mendrick, Mark C.; Randive, Rajul; Schowalter, Leo J.] Crystal IS, Green Isl, NY 12183 USA. [Rodak, Lee E.; Sampath, Anand V.; Wraback, Michael] Army Res Lab, Adelphi, MD 20783 USA. RP Moe, CG (reprint author), Crystal IS, 70 Cohoes Ave, Green Isl, NY 12183 USA. EM moe@crystal-is.com NR 4 TC 0 Z9 0 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2160-9020 BN 978-1-55752-973-2 J9 CONF LASER ELECTR PY 2013 PG 2 WC Engineering, Electrical & Electronic; Optics; Physics, Applied SC Engineering; Optics; Physics GA BC7WX UT WOS:000355262503263 ER PT S AU Wunderer, T Northrup, JE Yang, ZH Teepe, M Johnson, NM Rotella, P Wraback, M AF Wunderer, Thomas Northrup, John E. Yang, Zhihong Teepe, Mark Johnson, Noble M. Rotella, Paul Wraback, Michael GP IEEE TI Nitride VECSELs as Light Sources for Biomedical Applications SO 2013 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO) SE Conference on Lasers and Electro-Optics LA English DT Proceedings Paper CT Conference on Lasers and Electro-Optics (CLEO) CY JUN 09-14, 2013 CL San Jose, CA AB In-well-pumped blue InGaN/GaN vertical-external-cavity surface-emitting lasers are demonstrated. The laser structures were grown on bulk GaN substrates by using metal-organic vapor phase epitaxy near atmospheric pressure. The active zone consisted of up to 20 InGaN quantum wells distributed in a resonant periodic gain configuration. High-reflectivity dielectric distributed Bragg-reflectors were used as mirrors. Laser emission with a single longitudinal mode at 440 nm was achieved by exclusively pumping the quantum wells with the 384 nm emission line of a dye-/N2-laser. C1 [Wunderer, Thomas; Northrup, John E.; Yang, Zhihong; Teepe, Mark; Johnson, Noble M.] Palo Alto Res Ctr Inc, Palo Alto, CA 94301 USA. [Rotella, Paul; Wraback, Michael] US Army Res Lab, Adelphi, MD 20783 USA. RP Wunderer, T (reprint author), Palo Alto Res Ctr Inc, 3333 Coyote Hill Rd, Palo Alto, CA 94301 USA. EM thomas.wunderer@parc.com NR 4 TC 0 Z9 0 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2160-9020 BN 978-1-55752-973-2 J9 CONF LASER ELECTR PY 2013 PG 2 WC Engineering, Electrical & Electronic; Optics; Physics, Applied SC Engineering; Optics; Physics GA BC7WX UT WOS:000355262503259 ER PT S AU Richie, DA Ross, JA Park, SJ Shires, DR AF Richie, David A. Ross, James A. Park, Song J. Shires, Dale R. BE Chen, J Cuzzocrea, A Yang, LT TI Ray-Tracing-Based Geospatial Optimization for Heterogeneous Architectures Enhancing Situational Awareness SO 2013 IEEE 16TH INTERNATIONAL CONFERENCE ON COMPUTATIONAL SCIENCE AND ENGINEERING (CSE 2013) SE IEEE International Conference on Computational Science and Engineering LA English DT Proceedings Paper CT IEEE 16th International Conference on Computational Science and Engineering (CSE) CY DEC 03-05, 2013 CL Sydney, AUSTRALIA SP IEEE, Univ Technol Sydney, CSIRO, IEEE Tech Comm Scalable Comp, IEEE Comp Soc DE GPGPU; parallel computing; heterogeneous systems; line-of-sight; geospatial optimization ID COVERAGE AB This paper presents the implementation of ray-tracing-based algorithms for multi-objective geospatial optimization targeting various many-core processing technologies such as graphics processing units, x86 multi-cores, and ARM processors. High performance is achieved through highly parallel core algorithms, executed on multiple compute devices across a heterogeneous architecture using low-level OpenCL kernels. Algorithms for calculating line-of-sight ballistic threat, visual observability, ground plane extraction, and Markov chain Monte Carlo optimization provide an augmented geospatial intelligence and situational awareness in three-dimensional urban environments. C1 [Richie, David A.] Brown Deer Technol, Forest Hill, MD 21050 USA. [Ross, James A.] Dynam Res Corp, Andover, MA 01810 USA. [Park, Song J.; Shires, Dale R.] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA. RP Richie, DA (reprint author), Brown Deer Technol, Forest Hill, MD 21050 USA. EM drichie@browndeertechnology.com; jaross@drc.com; song.j.park.civ@mail.mil; dale.r.shires.civ@mail.mil NR 15 TC 0 Z9 0 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1949-0828 J9 IEEE INT C COMPUT PY 2013 BP 81 EP 86 DI 10.1109/CSE.2013.22 PG 6 WC Computer Science, Theory & Methods SC Computer Science GA BC3TK UT WOS:000351950300012 ER PT S AU Kim, Y Mohan, S Siegel, JB Stefanopoulou, AG Ding, Y AF Kim, Youngki Mohan, Shankar Siegel, Jason B. Stefanopoulou, Anna G. Ding, Yi GP IEEE TI The Estimation of Radial Temperature Distribution in Cylindrical Battery Cells under Unknown Cooling Conditions SO 2013 IEEE 52ND ANNUAL CONFERENCE ON DECISION AND CONTROL (CDC) SE IEEE Conference on Decision and Control LA English DT Proceedings Paper CT 52nd IEEE Annual Conference on Decision and Control (CDC) CY DEC 10-13, 2013 CL Florence, ITALY SP Honeywell, MathWorks, Springer, Taylor & Francis, Univ Trieste, Elsevier, GE Global Res, Natl Instruments, PendCon, Soc Ind & Appl Math, Wolfram, Journal Franklin Inst, United Technologies Res Ctr, Danieli Automat ID LITHIUM-ION BATTERY; THERMAL-ANALYSIS; PERFORMANCE; ELECTRODE AB The estimation of temperature inside a battery cell requires accurate information about the cooling condition even when the battery surface temperature is measured. This paper presents a model-based approach for estimating the temperature distribution inside a cylindrical battery under the unknown convective cooling condition. A reduced order thermal model using a polynomial approximation of the temperature profile inside the battery is used. A Dual Extended Kalman Filter (DEKF) is then applied for the identification of the convection coefficient and the estimation of the battery core temperature. Experimental results show that the proposed DEKF-based estimation method can provide an accurate prediction of the core temperature under the unknown cooling condition by measuring the battery current and voltage along with surface and ambient temperatures. C1 [Kim, Youngki; Siegel, Jason B.; Stefanopoulou, Anna G.] Univ Michigan, Dept Mech Engn, Ann Arbor, MI 48109 USA. [Mohan, Shankar] Univ Michigan, Dept Elect Engn, Ann Arbor, MI 48109 USA. [Ding, Yi] US Army, TARDEC, Warren, MI 48397 USA. RP Kim, Y (reprint author), Univ Michigan, Dept Mech Engn, Ann Arbor, MI 48109 USA. EM youngki@umich.edu; elemsn@umich.edu; siegeljb@umich.edu; annastef@umich.edu; yi.ding8.civ@mail.mil OI Mohan, Shankar/0000-0002-6107-7672 NR 20 TC 1 Z9 1 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 0743-1546 BN 978-1-4673-5717-3 J9 IEEE DECIS CONTR P PY 2013 BP 5680 EP 5685 PG 6 WC Automation & Control Systems; Engineering, Electrical & Electronic SC Automation & Control Systems; Engineering GA BC4AR UT WOS:000352223506067 ER PT J AU Gupta, M Gao, J Yan, XF Cam, H Han, JW AF Gupta, Manish Gao, Jing Yan, Xifeng Cam, Hasan Han, Jiawei BE Ozyer, T Carrington, P TI On Detecting Association-Based Clique Outliers In Heterogeneous Information Networks SO 2013 IEEE/ACM INTERNATIONAL CONFERENCE ON ADVANCES IN SOCIAL NETWORKS ANALYSIS AND MINING (ASONAM) LA English DT Proceedings Paper CT IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM) CY AUG 25-28, 2013 CL Niagara Falls, CANADA SP IEEE, Assoc Comp Machinery, Assoc Comp Machinery SIGKDD, IEEE Comp Soc, IEEE TCDE, Global Univ, Hellen American Univ, Springer, Microsoft, EXtra, Springer Verlag, Assoc Comp Machinery SIGMOD AB In the real world, various systems can be modeled using heterogeneous networks which consist of entities of different types. People like to discover groups (or cliques) of entities linked to each other with rare and surprising associations from such networks. We define such anomalous cliques as Association-Based Clique Outliers (ABCOutliers) for heterogeneous information networks, and design effective approaches to detect them. The need to find such outlier cliques from networks can be formulated as a conjunctive select query consisting of a set of (type, predicate) pairs. Answering such conjunctive queries efficiently involves two main challenges: (1) computing all matching cliques which satisfy the query and (2) ranking such results based on the rarity and the interestingness of the associations among entities in the cliques. In this paper, we address these two challenges as follows. First, we introduce a new low-cost graph index to assist clique matching. Second, we define the outlierness of an association between two entities based on their attribute values and provide a methodology to efficiently compute such outliers given a conjunctive select query. Experimental results on several synthetic datasets and the Wikipedia dataset containing thousands of entities show the effectiveness of the proposed approach in computing interesting ABCOutliers. C1 [Gupta, Manish] Microsoft, Hyderabad, Andhra Pradesh, India. [Gao, Jing] SUNY Buffalo, Buffalo, NY 14260 USA. [Yan, Xifeng] Univ Calif Santa Barbara, Santa Barbara, CA 93106 USA. [Cam, Hasan] US Army Res Lab, Adelphi, MD USA. [Han, Jiawei] Univ Illinois, Champaign, IL USA. RP Gupta, M (reprint author), Microsoft, Hyderabad, Andhra Pradesh, India. EM gmanish@microsoft.com; jing@buffalo.edu; xyan@cs.ucsb.edu; hasan.cam.civ@mail.mil; hanj@cs.uiuc.edu NR 12 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4503-2240-9 PY 2013 BP 114 EP 121 PG 8 WC Computer Science, Information Systems; Computer Science, Theory & Methods SC Computer Science GA BC5YC UT WOS:000353639700018 ER PT J AU Paulo, D Fischl, B Markow, T Martin, M Shakarian, P AF Paulo, Damon Fischl, Bradley Markow, Tanya Martin, Michael Shakarian, Paulo BE Ozyer, T Carrington, P TI Social Network Intelligence Analysis to Combat Street Gang Violence SO 2013 IEEE/ACM INTERNATIONAL CONFERENCE ON ADVANCES IN SOCIAL NETWORKS ANALYSIS AND MINING (ASONAM) LA English DT Proceedings Paper CT IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM) CY AUG 25-28, 2013 CL Niagara Falls, CANADA SP IEEE, Assoc Comp Machinery, Assoc Comp Machinery SIGKDD, IEEE Comp Soc, IEEE TCDE, Global Univ, Hellen American Univ, Springer, Microsoft, EXtra, Springer Verlag, Assoc Comp Machinery SIGMOD DE complex networks; social networks; criminology AB In this paper we introduce the Organization, Relationship, and Contact Analyzer (ORCA) that is designed to aide intelligence analysis for law enforcement operations against violent street gangs. ORCA is designed to address several police analytical needs concerning street gangs using new techniques in social network analysis. Specifically, it can determine "degree of membership" for individuals who do not admit to membership in a street gang, quickly identify sets of influential individuals (under the tipping model), and identify criminal ecosystems by decomposing gangs into sub-groups. We describe this software and the design decisions considered in building an intelligence analysis tool created specifically for countering violent street gangs as well as provide results based on conducting analysis on real-world police data provided by a major American metropolitan police department who is partnering with us and currently deploying this system for real-world use. C1 [Paulo, Damon] US Mil Acad, Network Sci Ctr, West Point, NY 10996 USA. US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA. RP Paulo, D (reprint author), US Mil Acad, Network Sci Ctr, West Point, NY 10996 USA. EM damon.paulo@usma.edu; bradley.fischl@usma.edu; tanya.markow@usma.edu; michael.martinl@usma.edu; paulo@shakarian.net NR 17 TC 0 Z9 0 U1 1 U2 5 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4503-2240-9 PY 2013 BP 1042 EP 1049 PG 8 WC Computer Science, Information Systems; Computer Science, Theory & Methods SC Computer Science GA BC5YC UT WOS:000353639700151 ER PT J AU Hoang, MX Ramanathan, R Moore, TJ Swami, A AF Hoang, Minh X. Ramanathan, Ram Moore, Terrence J. Swami, Ananthram BE Ozyer, T Carrington, P TI Structural and Collaborative Properties of Team Science Networks SO 2013 IEEE/ACM INTERNATIONAL CONFERENCE ON ADVANCES IN SOCIAL NETWORKS ANALYSIS AND MINING (ASONAM) LA English DT Proceedings Paper CT IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM) CY AUG 25-28, 2013 CL Niagara Falls, CANADA SP IEEE, Assoc Comp Machinery, Assoc Comp Machinery SIGKDD, IEEE Comp Soc, IEEE TCDE, Global Univ, Hellen American Univ, Springer, Microsoft, EXtra, Springer Verlag, Assoc Comp Machinery SIGMOD ID PERFORMANCE; LAW; DISTRIBUTIONS; INDIVIDUALS AB Team science is a collaborative approach to research, typically with researchers drawn from different disciplines. Team science networks have certain unique characteristics in their conception and intent that set them apart from other commonly studied social and collaboration networks. We study the structural properties, and present metrics for collaborative performance assessment in two real-world team science networks initiated by the Army Research Lab. We model a team using a higher-order generalization of an edge called a simplex. A simplex captures group relationships distinct from the union of pairwise relationships. Our evaluation using a rigorous methodology reveals that the distributions of vertex and facet degrees (the number of maximal groups that a vertex belongs to) follow a power law, but with exponential cut-off at the tail in most cases. We propose metrics for quantitatively assessing the extent of intra-team and extra-team collaborations, and compare their effectiveness vis-a-vis our intuitive notions. Our work can be used as the basis for generative models, and for evaluating the collaborative performance of team science networks. C1 [Hoang, Minh X.] Univ Calif Santa Barbara, Dept Comp Sci, Santa Barbara, CA 93106 USA. [Ramanathan, Ram] Raytheon BBN Technol, Cambridge, MA USA. [Moore, Terrence J.; Swami, Ananthram] Army Res Lab, Adelphi, MD USA. RP Hoang, MX (reprint author), Univ Calif Santa Barbara, Dept Comp Sci, Santa Barbara, CA 93106 USA. EM mhoang@cs.ucsb.edu; ramanath@bbn.com; terrence.j.moore.civ@mail.mil; ananthram.swami.civ@mail.mil NR 18 TC 0 Z9 0 U1 1 U2 3 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA BN 978-1-4503-2240-9 PY 2013 BP 1102 EP 1109 PG 8 WC Computer Science, Information Systems; Computer Science, Theory & Methods SC Computer Science GA BC5YC UT WOS:000353639700164 ER PT S AU Yu, W Zhang, HL Ge, LQ Hardy, R AF Yu, Wei Zhang, Hanlin Ge, Linqiang Hardy, Rommie GP IEEE TI On Behavior-based Detection of Malware on Android Platform SO 2013 IEEE GLOBAL COMMUNICATIONS CONFERENCE (GLOBECOM) SE IEEE Global Communications Conference LA English DT Proceedings Paper CT IEEE Global Communications Conference (GLOBECOM) CY DEC 09-13, 2013 CL Atlanta, GA SP IEEE DE Android; Malware Detection; Machine Learning; System Calls AB Because of exponential growth in smart mobile devices, malware attacks on smart mobile devices have been growing and pose serious threats to mobile device users. To address this issue, we develop a malware detection system, which uses a behavior-based detection approach to deal with the detection of a large number of unknown malware. To accurately detect malware, we examine system calls to capture the runtime behavior of software, which interacts with an operating system and adopt machine learning approaches such as Support Vector Machine (SVM) and Naive Bayes learning schemes to learn the dynamic behavior of software execution. Using real-world malware and benign samples, we conduct experiments on Android devices and evaluate the effectiveness of our developed system in terms of learning algorithms, the size of training set, the length of n-grams, and the overhead in training and detection processes. Our experimental data demonstrates the effectiveness of our proposed detection system to detect malware. C1 [Yu, Wei; Zhang, Hanlin; Ge, Linqiang] Towson Univ, Towson, MD 21252 USA. [Hardy, Rommie] US Army Res Lab, Adelphi, MD USA. RP Yu, W (reprint author), Towson Univ, Towson, MD 21252 USA. EM wyu@towson.edu; hzhang4@students.towson.edu; lge2@students.towson.edu; rommie.l.hardy.civ@mail.mil OI Zhang, Hanlin/0000-0001-8869-6863 NR 18 TC 1 Z9 1 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2334-0983 BN 978-1-4799-1353-4 J9 IEEE GLOB COMM CONF PY 2013 BP 814 EP 819 PG 6 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BD0LG UT WOS:000357299600137 ER PT S AU Ma, L He, T Leung, KK Swami, A Towsley, D AF Ma, Liang He, Ting Leung, Kin K. Swami, Ananthram Towsley, Don GP IEEE TI Link Identifiability in Communication Networks with Two Monitors SO 2013 IEEE GLOBAL COMMUNICATIONS CONFERENCE (GLOBECOM) SE IEEE Global Communications Conference LA English DT Proceedings Paper CT IEEE Global Communications Conference (GLOBECOM) CY DEC 09-13, 2013 CL Atlanta, GA SP IEEE AB We investigate the problem of identifying individual link performance metrics in a communication network by measuring end-to-end metrics of selected paths between monitors, under the assumption that link metrics are additive and constant during the measurement, and measurement paths cannot contain cycles. In a previous work, we developed an algorithm that places the minimum number of monitors to identify all link metrics. However, even the minimum number can be large in some practical networks (e.g., 60% of all the nodes), suggesting high monitor deployment cost. In this paper, we study the dual problem where given a fixed number of monitors, we want to place them to maximize the number of identifiable link metrics, with concrete results for the case of two monitors. The significance of the two-monitor case is that all the tomographic computation can be performed at the destination monitor without shipping measurements to a central node, thus enabling endhost-based network monitoring. We develop an efficient algorithm to determine all identifiable links in an arbitrary network with a given placement of two monitors, based on which we propose an optimal two-monitor placement algorithm to maximize the number of identifiable links. Our evaluation on real ISP topologies shows that although a large number of monitors is needed to identify all link metrics, we can usually identify a substantial portion (up to 97%) of the links using a single pair of optimally placed monitors. C1 [Ma, Liang; Leung, Kin K.] Univ London Imperial Coll Sci Technol & Med, London, England. [He, Ting] IBM TJ Watson Res Ctr, Yorktown Hts, NY USA. [Swami, Ananthram] Army Res Lab, Adelphi, MD USA. [Towsley, Don] Univ Massachusetts, Amherst, MA 01003 USA. RP Ma, L (reprint author), Univ London Imperial Coll Sci Technol & Med, London, England. EM l.ma10@imperial.ac.uk; the@us.ibm.com; kin.leung@imperial.ac.uk; ananthram.swami.civ@mail.mil; towsley@cs.umass.edu NR 14 TC 2 Z9 2 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2334-0983 BN 978-1-4799-1353-4 J9 IEEE GLOB COMM CONF PY 2013 BP 1513 EP 1518 PG 6 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BD0LG UT WOS:000357299601097 ER PT S AU Talarico, S Valenti, MC Torrieri, D AF Talarico, Salvatore Valenti, Matthew C. Torrieri, Don GP IEEE TI Analysis of Multi-Cell Downlink Cooperation with a Constrained Spatial Model SO 2013 IEEE GLOBAL COMMUNICATIONS CONFERENCE (GLOBECOM) SE IEEE Global Communications Conference LA English DT Proceedings Paper CT IEEE Global Communications Conference (GLOBECOM) CY DEC 09-13, 2013 CL Atlanta, GA SP IEEE ID NETWORKS AB Multi-cell cooperation (MCC) mitigates intercell interference and improves throughput at the cell edge. This paper considers a cooperative downlink, whereby cell-edge mobiles are served by multiple cooperative base stations. The cooperating base stations transmit identical signals over paths with nonidentical path losses, and the receiving mobile performs diversity combining. The analysis in this paper is driven by a new expression for the conditional outage probability when signals arriving over different paths are combined in the presence of noise and interference, where the conditioning is with respect to the network topology and shadowing. The channel model accounts for path loss, shadowing, and Nakagami fading, and the Nakagami fading parameters do not need to be identical for all paths. To study performance over a wide class of network topologies, a random spatial model is adopted, and performance is found by statistically characterizing the rates provided on the downlinks. To model realistic networks, the model requires a minimum separation among base stations. Having adopted a realistic model and an accurate analysis, the paper proceeds to determine performance under several resource-allocation policies and provides insight regarding how the cell edge should be defined. C1 [Talarico, Salvatore; Valenti, Matthew C.] W Virginia Univ, Morgantown, WV 26506 USA. [Torrieri, Don] US Army, Res Lab, Adelphi, MD USA. RP Talarico, S (reprint author), W Virginia Univ, Morgantown, WV 26506 USA. OI Valenti, Matthew/0000-0001-6089-0509 NR 14 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2334-0983 BN 978-1-4799-1353-4 J9 IEEE GLOB COMM CONF PY 2013 BP 3631 EP 3636 PG 6 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BD0LG UT WOS:000357299603121 ER PT S AU Tsiligkaridis, T Sadler, BM Hero, AO AF Tsiligkaridis, Theodoros Sadler, Brian M. Hero, Alfred O., III GP IEEE TI Blind Collaborative 20 Questions for Target Localization SO 2013 IEEE GLOBAL CONFERENCE ON SIGNAL AND INFORMATION PROCESSING (GLOBALSIP) SE IEEE Global Conference on Signal and Information Processing LA English DT Proceedings Paper CT IEEE Global Conference on Signal and Information Processing (GlobalSIP) CY DEC 03-05, 2013 CL Austin, TX SP Inst Elect & Elect Engineers, IEEE Signal Proc Soc AB We consider the problem of collaborative target localization by several observers, called players, where the reliability of each player is unknown. As in our previous work [1] we formulate this problem as a 20 questions game with noise for collaborative players under a minimum entropy criterion. We extend the setting of [1] to the case where the players' error channels have unknown crossover probabilities. First, we use dynamic programming to characterize the structure of the optimal policy for constructing the sequence of questions. This generalizes the multiplayer policies derived in [1] for the known error channel setting. Second, we prove a separation theorem showing that a sequential bisection scheme achieves the same performance as the optimal joint queries. This generalizes the separation theorem recently derived for the known error channel case in [1]. Third, we derive bounds for the maximum entropy loss per iteration. Finally, we show that even for the one-dimensional case, the optimal query policy for the unknown error channel is not equivalent to a probabilistic bisection policy. This framework provides a methodology for simultaneous sequential estimation of target location and learning the error channels associated with the players. C1 [Tsiligkaridis, Theodoros; Hero, Alfred O., III] Univ Michigan, Dept EECS, Ann Arbor, MI 48109 USA. [Sadler, Brian M.] US Army, Res Lab, Adelphi, MD USA. [Hero, Alfred O., III] Univ Michigan, Dept Stat, Ann Arbor, MI 48109 USA. RP Tsiligkaridis, T (reprint author), Univ Michigan, Dept EECS, Ann Arbor, MI 48109 USA. EM ttsili@umich.edu; brian.m.sadler6.civ@mail.mil; hero@umich.edu NR 5 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2376-4066 BN 978-1-4799-0248-4 J9 IEEE GLOB CONF SIG PY 2013 BP 161 EP 164 PG 4 WC Engineering, Electrical & Electronic SC Engineering GA BC2FE UT WOS:000350825600045 ER PT S AU Cohen, K Zhao, Q Swami, A AF Cohen, Kobi Zhao, Qing Swami, Ananthram GP IEEE TI Optimal Index Policies for Quickest Localization of Anomaly in Cyber Networks SO 2013 IEEE GLOBAL CONFERENCE ON SIGNAL AND INFORMATION PROCESSING (GLOBALSIP) SE IEEE Global Conference on Signal and Information Processing LA English DT Proceedings Paper CT IEEE Global Conference on Signal and Information Processing (GlobalSIP) CY DEC 03-05, 2013 CL Austin, TX SP Inst Elect & Elect Engineers, IEEE Signal Proc Soc DE Anomaly detection; intrusion detection; sequential hypothesis testing ID WIRELESS SENSOR NETWORKS; COMPOSITE HYPOTHESES; SEQUENTIAL PROCEDURE AB We consider the problem of quickest localization of anomaly in a resource-constrained cyber network consisting of multiple components. Due to resource constraints, only one component can be probed at each time. The observations are random realizations drawn from two different distributions depending on whether the component is normal or anomalous. Components are assigned priorities. Components with higher priorities in an abnormal state should be fixed before components with lower priorities to reduce the overall damage to the network. The objective is to minimize the expected weighted sum of completion times of abnormal components subject to error probability constraints. We consider two different anomaly models: the independent model in which each component can be abnormal independent of other components, and the exclusive model in which there is one and only one abnormal component. We develop index policies under both models. Optimal low-complexity algorithms are derived for the simple hypotheses case, where the distribution is completely known under both hypotheses. Asymptotically (as the error probability approaches zero) optimal low-complexity algorithms are derived for the composite hypotheses case, where there is uncertainty in the distribution parameters. Simulation results then illustrate the performance of the algorithms. C1 [Cohen, Kobi; Zhao, Qing] Univ Calif Davis, Dept Elect & Comp Engn, Davis, CA 95616 USA. [Swami, Ananthram] Army Res Lab, Adelphi, MD 20783 USA. RP Cohen, K (reprint author), Univ Calif Davis, Dept Elect & Comp Engn, Davis, CA 95616 USA. EM yscohen@ucdavis.edu; qzhao@ucdavis.edu; a.swami@ieee.org NR 24 TC 2 Z9 2 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2376-4066 BN 978-1-4799-0248-4 J9 IEEE GLOB CONF SIG PY 2013 BP 221 EP 224 PG 4 WC Engineering, Electrical & Electronic SC Engineering GA BC2FE UT WOS:000350825600060 ER PT S AU Wilkerson, AC Chintakunta, H Krim, H Moore, TJ Swami, A AF Wilkerson, Adam C. Chintakunta, Harish Krim, Hamid Moore, Terrence J. Swami, Ananthram GP IEEE TI A Distributed Collapse of a Network's Dimensionality SO 2013 IEEE GLOBAL CONFERENCE ON SIGNAL AND INFORMATION PROCESSING (GLOBALSIP) SE IEEE Global Conference on Signal and Information Processing LA English DT Proceedings Paper CT IEEE Global Conference on Signal and Information Processing (GlobalSIP) CY DEC 03-05, 2013 CL Austin, TX SP Inst Elect & Elect Engineers, IEEE Signal Proc Soc DE Hole Localization; Simplicial Complex; Simplicial Collapse; Sensor Network Coverage; Homology AB Algebraic topology has been successfully applied to detect and localize sensor network coverage holes with minimal assumptions on sensor locations. These methods all use a computation of topological invariants called homology spaces. We develop a distributed algorithm for collapsing a sensor network, hence simplifying its analysis. We prove that the collapse is equivalent to a previously developed strong collapse in that it preserves coverage hole locations. In this way, the collapse simplifies the network without losing crucial information about the coverage region. We show that the algorithm requires only one-hop information in a communication network, making it faster than clique-finding algorithms that increase the number of computations necessary for hole localization. This makes it an effective pre-processing step to finding network coverage holes. C1 [Wilkerson, Adam C.; Chintakunta, Harish; Krim, Hamid] N Carolina State Univ, Dept Elect & Comp Engn, Raleigh, NC 27695 USA. [Moore, Terrence J.; Swami, Ananthram] Army Res Lab, Adelphi, MD USA. RP Wilkerson, AC (reprint author), N Carolina State Univ, Dept Elect & Comp Engn, Raleigh, NC 27695 USA. NR 15 TC 2 Z9 2 U1 0 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2376-4066 BN 978-1-4799-0248-4 J9 IEEE GLOB CONF SIG PY 2013 BP 595 EP 598 PG 4 WC Engineering, Electrical & Electronic SC Engineering GA BC2FE UT WOS:000350825600152 ER PT S AU Mait, JN Schuetz, CA Shi, S Prather, DW Martin, RD Curt, PF Bonnett, J AF Mait, Joseph N. Schuetz, Christopher A. Shi, Shouyuan Prather, Dennis W. Martin, Richard D. Curt, Petersen F. Bonnett, James GP IEEE TI Minimum Bias Design for a Distributed Aperture Millimeter Wave Imager SO 2013 IEEE GLOBAL CONFERENCE ON SIGNAL AND INFORMATION PROCESSING (GLOBALSIP) SE IEEE Global Conference on Signal and Information Processing LA English DT Proceedings Paper CT IEEE Global Conference on Signal and Information Processing (GlobalSIP) CY DEC 03-05, 2013 CL Austin, TX SP Inst Elect & Elect Engineers, IEEE Signal Proc Soc AB Recently, new techniques for passive imaging based on distributed aperture imagers have been developed. One promising approach utilizes photonic sampling, routing, and processing of the millimeter-wave energy for image generation. Many signal processing aspects of this approach that have been explored to date, from engineering phase profiles across the array to achieve dynamically adjustable point spread functions, to noise reduction techniques in the optical image regeneration. Herein, we focus on a method to reduce image bias in a distributed aperture millimeter wave imager by switching the phase in individual channels by pi-phase. Our simulations indicate this approach has better bias performance than random phase switching. C1 [Mait, Joseph N.] US Army, Res Lab, Adelphi, MD 20783 USA. [Schuetz, Christopher A.; Shi, Shouyuan; Prather, Dennis W.] Univ Delaware, Dept Elect & Comp Engn, Newark, DE 19716 USA. [Martin, Richard D.] Phase Sensit Innovat, Newark, DE 19711 USA. [Curt, Petersen F.; Bonnett, James] EM Photon Inc, Newark, DE 19711 USA. RP Mait, JN (reprint author), US Army, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA. NR 6 TC 1 Z9 1 U1 2 U2 2 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2376-4066 BN 978-1-4799-0248-4 J9 IEEE GLOB CONF SIG PY 2013 BP 711 EP 714 PG 4 WC Engineering, Electrical & Electronic SC Engineering GA BC2FE UT WOS:000350825600194 ER PT S AU Fink, J Twigg, J Yu, P Sadler, BM AF Fink, Jonathan Twigg, Jeffrey Yu, Paul Sadler, Brian M. GP IEEE TI A Parsimonious Model for Wireless Connectivity in Robotic Networks SO 2013 IEEE GLOBAL CONFERENCE ON SIGNAL AND INFORMATION PROCESSING (GLOBALSIP) SE IEEE Global Conference on Signal and Information Processing LA English DT Proceedings Paper CT IEEE Global Conference on Signal and Information Processing (GlobalSIP) CY DEC 03-05, 2013 CL Austin, TX SP Inst Elect & Elect Engineers, IEEE Signal Proc Soc AB We present a minimalist model for estimating point-to- point wireless connectivity in robotic networks where every node in the network is mobile, i.e., the space of the problem is truly R-2 x R-2. This model is built on the idea that the geometry of an environment leads to a region-based decomposition where communication between pairs of regions can be approximated accurately by simple stochastic models. We develop an estimation framework that allows for these simple stochastic models to be predicted and updated based on sparse measurements as demonstrated experimentally. C1 [Fink, Jonathan; Twigg, Jeffrey; Yu, Paul; Sadler, Brian M.] US Army, Res Lab, Adelphi, MD 20783 USA. RP Fink, J (reprint author), US Army, Res Lab, Adelphi, MD 20783 USA. NR 10 TC 0 Z9 0 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 2376-4066 BN 978-1-4799-0248-4 J9 IEEE GLOB CONF SIG PY 2013 BP 855 EP 858 PG 4 WC Engineering, Electrical & Electronic SC Engineering GA BC2FE UT WOS:000350825600230 ER PT S AU Torrieri, D Valenti, MC Talarico, S AF Torrieri, Don Valenti, Matthew C. Talarico, Salvatore GP IEEE TI A New Analysis of the DS-CDMA Cellular Uplink Under Spatial Constraints SO 2013 IEEE INTERNATIONAL CONFERENCE ON COMMUNICATIONS (ICC) SE IEEE International Conference on Communications LA English DT Proceedings Paper CT IEEE International Conference on Communications (ICC) CY JUN 09-13, 2013 CL Budapest, HUNGARY SP IEEE ID PERFORMANCE; CAPACITY; SYSTEMS AB A new analysis is presented for the direct-sequence code-division multiple access (DS-CDMA) cellular uplink. For a given network topology, closed-form expressions are found for the outage probability and rate of each uplink in the presence of path-dependent Nakagami fading and log-normal shadowing. The topology may be arbitrary or modeled by a random spatial distribution for a fixed number of base stations and mobiles placed over a finite area with the separations among them constrained to exceed a minimum distance. The analysis is more detailed and accurate than existing ones and facilitates the resolution of network design issues, including the influence of the minimum base-station separation, the role of the spreading factor, and the impact of various power-control and rate-control policies. It is shown that once power control is established, the rate can be allocated according to a fixed-rate or variable-rate policy with the objective of either meeting an outage constraint or maximizing throughput. An advantage of the variable-rate policy is that it allows an outage constraint to be enforced on every uplink, whereas the fixed-rate policy can only meet an average outage constraint. C1 [Torrieri, Don] US Army, Res Lab, Adelphi, MD 20783 USA. [Valenti, Matthew C.; Talarico, Salvatore] West Virginia Univ, Morgantown, WV USA. RP Torrieri, D (reprint author), US Army, Res Lab, Adelphi, MD 20783 USA. OI Valenti, Matthew/0000-0001-6089-0509 FU National Science Foundation [CNS-0750821] FX M.C. Valenti and S. Talarico were sponsored by the National Science Foundation under Award No. CNS-0750821. NR 12 TC 0 Z9 0 U1 0 U2 0 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1550-3607 BN 978-1-4673-3122-7 J9 IEEE ICC PY 2013 BP 5360 EP + PG 2 WC Telecommunications SC Telecommunications GA BC0WB UT WOS:000349673805124 ER PT S AU Valenti, MC Torrieri, D Talarico, S AF Valenti, Matthew C. Torrieri, Don Talarico, Salvatore GP IEEE TI Adjacent-Channel Interference in Frequency-Hopping Ad Hoc Networks SO 2013 IEEE INTERNATIONAL CONFERENCE ON COMMUNICATIONS (ICC) SE IEEE International Conference on Communications LA English DT Proceedings Paper CT IEEE International Conference on Communications (ICC) CY JUN 09-13, 2013 CL Budapest, HUNGARY SP IEEE AB This paper considers ad hoc networks that use the combination of coded continuous-phase frequency-shift keying (CPFSK) and frequency-hopping multiple access. Although CPFSK has a compact spectrum, some of the signal power inevitably splatters into adjacent frequency channels, thereby causing adjacent-channel interference (ACI). The amount of ACI is controlled by setting the fractional in-band power; i.e., the fraction of the signal power that lies within the band of each frequency channel. While this quantity is often selected arbitrarily, a tradeoff is involved in the choice. This paper presents a new analysis of frequency-hopping ad hoc networks that carefully incorporates the effect of ACI. The analysis accounts for the shadowing, Nakagami fading, CPFSK modulation index, code rate, number of frequency channels, fractional in-band power, and spatial distribution of the interfering mobiles. Expressions are presented for both outage probability and transmission capacity. With the objective of maximizing the transmission capacity, the optimal fractional in-band power that should be contained in each frequency channel is identified. C1 [Valenti, Matthew C.; Talarico, Salvatore] West Virginia Univ, Morgantown, WV 26506 USA. [Torrieri, Don] US Army Res Lab, Adelphi, MD 20783 USA. RP Valenti, MC (reprint author), West Virginia Univ, Morgantown, WV 26506 USA. OI Valenti, Matthew/0000-0001-6089-0509 FU National Science Foundation [CNS-0750821] FX M.C. Valenti and S. Talarico were sponsored by the National Science Foundation under Award No. CNS-0750821. NR 8 TC 2 Z9 3 U1 0 U2 1 PU IEEE PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 USA SN 1550-3607 BN 978-1-4673-3122-7 J9 IEEE ICC PY 2013 BP 5583 EP + PG 2 WC Telecommunications SC Telecommunications GA BC0WB UT WOS:000349673806033 ER EF