FN Thomson Reuters Web of Science™
VR 1.0
PT S
AU Osgood, RM
Steeves, DM
Belton, LE
Welch, JR
Nagarajan, R
Quigley, C
Walsh, GF
Tabiryan, NV
Serak, S
Kimball, BR
AF Osgood, R. M., III
Steeves, D. M.
Belton, L. E.
Welch, J. R.
Nagarajan, R.
Quigley, Caitlin
Walsh, G. F.
Tabiryan, N. V.
Serak, S.
Kimball, B. R.
BE Bandaru, PR
Grego, S
Kinloch, I
TI Optical properties of nanoparticle-doped azobenzene liquid crystals
SO NANOTUBES, NANOWIRES, NANOBELTS AND NANOCOILS - PROMISE, EXPECTATIONS
AND STATUS
SE Materials Research Society Symposium Proceedings
LA English
DT Proceedings Paper
CT Symposium on Nanotubes, Nanowires, Nanobelts and Nanocoils held at the
2008 MRS Fall Meeting
CY DEC 01-04, 2008
CL Boston, MA
SP Mat Res Soc
AB Liquid crystals (LCs) are anisotropic fluids exhibiting orientational order that can be controlled with external fields. The optical nonlinearity of LCs can be enhanced by doping with azobenzene dyes or nanoparticles such as carbon nanotubes (CNTs). Previous studies have demonstrated modifications of the LC's nematic-isotropic phase transition temperature by the addition of CNTs. In the present paper, we disperse single-wall and multi-wall CNTs in LC cells at the level of 0.1% by weight. We find that the addition of CNTs enhances the response speed of the azobenzene LC. We have developed a theory that allows quantitative characterization of the nonlinear transmission process of a system of crossed polarizers comprising the LC cell.
C1 [Osgood, R. M., III; Steeves, D. M.; Belton, L. E.; Welch, J. R.; Nagarajan, R.; Quigley, Caitlin; Walsh, G. F.; Kimball, B. R.] US Army Natick Soldier Res, Ctr Dev & Engn, Natick, MA 01760 USA.
RP Osgood, RM (reprint author), US Army Natick Soldier Res, Ctr Dev & Engn, Natick, MA 01760 USA.
NR 15
TC 0
Z9 0
U1 2
U2 3
PU MATERIALS RESEARCH SOCIETY
PI WARRENDALE
PA 506 KEYSTONE DRIVE, WARRENDALE, PA 15088-7563 USA
SN 0272-9172
BN 978-1-60511-114-8
J9 MATER RES SOC SYMP P
PY 2009
VL 1142
BP 105
EP 113
PG 9
WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary
SC Science & Technology - Other Topics; Materials Science
GA BLF59
UT WOS:000270071200015
ER
PT S
AU Dave, JR
Williams, AJ
Yao, CP
Lu, XCM
Tortella, FC
AF Dave, Jitendra R.
Williams, Anthony J.
Yao, Changping
Lu, X. -C. May
Tortella, Frank C.
BE Ottens, AK
Wang, KKW
TI Modeling Cerebral Ischemia in Neuroproteomics
SO NEUROPROTEOMICS: METHODS AND PROTOCOLS
SE Methods in Molecular Biology
LA English
DT Article; Book Chapter
DE Ischemic brain injury; MCAo; Proteomics; 2D-gel electrophoresis; Mass
spectroscopy; Models of cerebral ischemia; Brain injury; Biomarkers
ID TRAUMATIC BRAIN-INJURY; INFLAMMATORY GENE-EXPRESSION; NMDA RECEPTOR
ANTAGONIST; ARTERY OCCLUSION; RAT MODEL; LEUKOCYTE INFILTRATION;
THROMBOEMBOLIC STROKE; THERAPEUTIC WINDOW; INHIBITOR MLN519; BLOOD-FLOW
AB Protein changes induced by traumatic or ischemic brain injury can serve as diagnostic markers as well as therapeutic targets for neuroprotection. The focus of this chapter is to provide a representative overview of preclinical brain injury and proteomics analysis protocols for evaluation and discovery of novel biomarkers. Detailed surgical procedures have been provided for inducing MCAo and implantation of chronic indwelling cannulas for drug delivery. Sample collection and tissue processing techniques for collection of blood, CSF, and brain are also described including standard biochemical methodology for the proteomic analysis of these tissues.
The dynamics of proteomic analysis is a multistep process comprising sample preparation, separation, quantification, and identification of proteins. Our approach is to separate proteins first by two-dimensional gel electrophoresis according to charge and molecular mass. Proteins are then fragmented and analyzed using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). Identification of proteins can be achieved by comparing the mass-to-charge data to protein sequences in respective databases.
C1 [Dave, Jitendra R.; Williams, Anthony J.; Yao, Changping; Lu, X. -C. May; Tortella, Frank C.] Walter Reed Army Inst Res, Dept Appl Neurobiol, Div Psychiat & Neurosci, Silver Spring, MD 20910 USA.
RP Dave, JR (reprint author), Walter Reed Army Inst Res, Dept Appl Neurobiol, Div Psychiat & Neurosci, Silver Spring, MD 20910 USA.
NR 42
TC 2
Z9 2
U1 1
U2 2
PU HUMANA PRESS INC
PI TOTOWA
PA 999 RIVERVIEW DR, STE 208, TOTOWA, NJ 07512-1165 USA
SN 1064-3745
BN 978-1-934115-84-8
J9 METHODS MOL BIOL
JI Methods Mol. Biol.
PY 2009
VL 566
BP 25
EP 40
DI 10.1007/978-1-59745-562-6_2
D2 10.1007/978-1-59745-562-6
PG 16
WC Biochemical Research Methods; Neurosciences
SC Biochemistry & Molecular Biology; Neurosciences & Neurology
GA BLU16
UT WOS:000271018600002
PM 20058162
ER
PT J
AU Williams, DJ
Creasy, WR
McGarvey, DJ
Fry, RA
Bevilacqua, VLH
Durst, HD
AF Williams, Daniel J.
Creasy, William R.
McGarvey, David J.
Fry, Roderick A.
Bevilacqua, Vicky L. H.
Durst, H. Dupont
TI Aluminium sulfate and sodium aluminate buffer solutions for the
destruction of phosphorus based chemical warfare agents
SO NEW JOURNAL OF CHEMISTRY
LA English
DT Article
ID DESTROYING VX; DETOXIFICATION
AB Nerve agents VX and GB (sarin) are sequestered and removed by aluminium sulfate and sodium aluminate mixtures adjusted to pH 4 in solution. The products of hydrolysis are removed with the alum floc below NMR detection limits over time depending and the amount of aluminium molar excess relative to agent. Half-lives for GB decomposition are 3.1 h and 1.1 h, respectively, for a 120 and a 1200 molar excess. For VX, the half-lives are 8.5 d and 2.9 d for a 240 and a 5000 molar aluminium excess. In the case of GB,fluorine is sequestered as the hexafluoroaluminate ion. In the case of VX, no phosphorus containing hydrolysis products including the very toxic S-[2-(diisopropyl-amino)-ethyl] methylphosphonothiolate (EA-2192) are detected in the hydrolysate.
C1 [Williams, Daniel J.] Kennesaw State Univ, Dept Chem & Biochem, Kennesaw, GA 30144 USA.
[Williams, Daniel J.; Creasy, William R.; Fry, Roderick A.] SAIC, Aberdeen Proving Ground, MD 21010 USA.
[McGarvey, David J.; Bevilacqua, Vicky L. H.; Durst, H. Dupont] USA, Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD 21010 USA.
RP Williams, DJ (reprint author), Kennesaw State Univ, Dept Chem & Biochem, Kennesaw, GA 30144 USA.
EM dwilliam@kennesaw.edu
NR 14
TC 2
Z9 2
U1 1
U2 5
PU ROYAL SOC CHEMISTRY
PI CAMBRIDGE
PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS,
ENGLAND
SN 1144-0546
J9 NEW J CHEM
JI New J. Chem.
PY 2009
VL 33
IS 5
BP 1006
EP 1009
DI 10.1039/b819885c
PG 4
WC Chemistry, Multidisciplinary
SC Chemistry
GA 442SH
UT WOS:000265860400010
ER
PT J
AU Casali, JG
Ahroon, WA
Lancaster, JA
AF Casali, John G.
Ahroon, William A.
Lancaster, Jeff A.
TI A field investigation of hearing protection and hearing enhancement in
one device: For soldiers whose ears and lives depend upon it
SO NOISE & HEALTH
LA English
DT Article
DE Headsets; hearing-assistive devices; hearing protection; military
operations; noise exposure; signal detection; speech communication;
weapons noise
AB Operational hearing protection and maintenance of audibility of signals and speech are considered force multipliers in military operations, increasing Soldier survivability and lethality. The in-field research described in this paper was conducted to examine operational performance effects of three different hearing enhancement protection systems (HEPS) that are intended to provide both protection and audibility. The experiment utilized operationally-defined measures in full-scale, simulated combat scenarios with Army ROTC Cadet Soldiers as subjects. The Soldiers operational performance was evaluated in two missions: reconnaissance and raid (attack on enemy camp). Both missions had substantial hearing requirements, including communications, signal detection/recognition, and distance judgments. Operational performance was measured by objective metrics of Squad performance, including the distances required to detect an enemy insurgent camp under each HEPS, and by subjective metrics, such as the Armys dimensions of combat-related mission success as evaluated by Army Officers who served as training leaders/observers. Other subjective ratings were obtained after each training exercise from both the Officers and the Soldiers, including detailed impressions about each HEPS after extended use. Two of the three HEPS were electronic sound transmission devices (comprising an ambient sound pass-through filtering and amplification circuit): a Peltor Comtac II circumaural headset (NRR=21; 16 dB maximum gain); and a Communications Enhancement Protection System (CEPS) (NRR=29; 36 dB maximum gain). One passive, level-dependent HEPS was used, the yellow end of the Combat Arms Earplug, which provides amplitude-sensitive attenuation that sharply increases when the ambient sound is above about 110 dB (e.g., due to a gunshot), but which provides an NRR of 0 and very little attenuation below 1000 Hz in lower ambient noise levels. In the military mission entailing location of and attack on an enemy camp, the CEPS device resulted in the longest (earliest) average auditory detection distance of the camp (400 feet), followed by the Peltor (233 feet) and then the Combat Arms Earplug (150 feet), in comparison to detection by the unprotected, normal ear at about 220 feet. Commanding officers ratings of mission performance and overall success slightly favored the electronic HEPS, but these ratings were dependent upon the particular mission undertaken. Ergonomics and usability issues abounded with the electronic HEPS, and the Soldiers subjective ratings showed variability across all three devices, with device preference depending upon the particular dimension being rated (e.g., comfort vs. hearing ability). Clearly, the results of this in-field experiment demonstrate that more development is needed to achieve the levels of hearing performance and user acceptance from the HEPS that is desirable and needed for combat conditions. In this vein, it is important to note that HEPS designs are continually evolving, and certain upgrades to the three devices evaluated in the late 2006 timeframe of this study have occurred and further evaluations are thus warranted.
C1 [Casali, John G.; Lancaster, Jeff A.] Virginia Tech, Auditory Syst Lab, Blacksburg, VA USA.
[Ahroon, William A.] USA, Aeromed Res Lab USAARL, Ft Rucker, AL USA.
RP Casali, JG (reprint author), Virginia Tech Univ, Grado Dept Ind & Syst Engn, ISE Dept, 519G,Whittemore Hall, Blacksburg, VA 24061 USA.
EM jcasali@vt.edu
NR 13
TC 21
Z9 22
U1 1
U2 6
PU MEDKNOW PUBLICATIONS
PI MUMBAI
PA B-9, KANARA BUSINESS CENTRE, OFF LINK RD, GHAKTOPAR-E, MUMBAI, 400075,
INDIA
SN 1463-1741
J9 NOISE HEALTH
JI Noise Health
PD JAN-MAR
PY 2009
VL 11
IS 42
BP 69
EP 90
DI 10.4103/1463-1741.48564
PG 22
WC Audiology & Speech-Language Pathology; Public, Environmental &
Occupational Health
SC Audiology & Speech-Language Pathology; Public, Environmental &
Occupational Health
GA V15SC
UT WOS:000207820700011
PM 19265256
ER
PT J
AU Cantu, V
Fries, JN
Ryan, TA
AF Cantu, Valentin
Fries, Joe N.
Ryan, Tom A.
TI An Apparatus for Separating Live Amphipods from Debris
SO NORTH AMERICAN JOURNAL OF AQUACULTURE
LA English
DT Article
ID HYALELLA-AZTECA AMPHIPODA; DYNAMICS; FISH; LAKE; POPULATIONS;
SALAMANDERS; PREDATION; WETLAND; FLORIDA; WATER
AB We designed an inexpensive (US$35), easy-to-build apparatus that separates live freshwater amphipods Hyalella azteca from debris. In 2 d of unattended operation, the separator provided an average of 2,700 amphipods from debris per square meter of raceway bottom (range 1,600-4,000/m(2); n = 3). Amphipod-containing debris collection, apparatus setup, and salt treatment of amphipods to kill hydras and flatworms took about 10 min.
C1 [Cantu, Valentin; Fries, Joe N.] US Fish & Wildlife Serv, San Marcos Natl Fish Hatchery & Technol Ctr, San Marcos, TX 78666 USA.
[Ryan, Tom A.] US Army Corps Engineers, Engn Res & Dev Ctr, Champaign, IL 61821 USA.
RP Cantu, V (reprint author), US Fish & Wildlife Serv, San Marcos Natl Fish Hatchery & Technol Ctr, San Marcos, TX 78666 USA.
EM valentin_cantu@fws.gov
NR 20
TC 1
Z9 1
U1 0
U2 3
PU AMER FISHERIES SOC
PI BETHESDA
PA 5410 GROSVENOR LANE SUITE 110, BETHESDA, MD 20814-2199 USA
SN 1522-2055
J9 N AM J AQUACULT
JI N. Am. J. Aqualcult.
PD JAN
PY 2009
VL 71
IS 1
BP 6
EP 9
DI 10.1577/A07-106.1
PG 4
WC Fisheries
SC Fisheries
GA 421NH
UT WOS:000264365100002
ER
PT J
AU Ravi, G
Alvarado, JL
Marsh, C
Kessler, DA
AF Ravi, Gurunarayana
Alvarado, Jorge L.
Marsh, Charles
Kessler, David A.
TI Laminar Flow Forced Convection Heat Transfer Behavior of a Phase Change
Material Fluid in Finned Tubes
SO NUMERICAL HEAT TRANSFER PART A-APPLICATIONS
LA English
DT Article
ID CHANGE-MATERIAL SLURRIES; CHANGE MATERIAL SUSPENSIONS; TRANSFER
ENHANCEMENT; WALL TEMPERATURE; CIRCULAR DUCTS; UNIFORM
AB The heat transfer behavior of phase change material fluid (PCM) under laminar flow conditions in circular tubes and internally longitudinal finned tubes was studied. An effective specific heat technique was used to model the phase change process. Heat transfer results for a smooth circular tube with PCM fluid were obtained under hydrodynamically and thermally fully developed conditions. Results for the finned tube were obtained using the H2 and T boundary conditions. It was determined that the Nusselt number was strongly dependent on the Stefan number, fin thermal conductivity value, and height of the fins.
C1 [Alvarado, Jorge L.] Texas A&M Univ, Dept Engn Technol & Ind Distribut, College Stn, TX 77843 USA.
[Ravi, Gurunarayana] Texas A&M Univ, Dept Mech Engn, College Stn, TX 77843 USA.
[Marsh, Charles] USA, Construct Engn Res Lab, Engn Res & Dev Ctr, Champaign, IL 61824 USA.
[Kessler, David A.] Naval Res Lab, Lab Computat Phys & Fluid Dynam, Washington, DC USA.
[Marsh, Charles] Univ Illinois, Dept Nucl Plasma & Radiol Engn, Urbana, IL 61801 USA.
RP Alvarado, JL (reprint author), Texas A&M Univ, Dept Engn Technol & Ind Distribut, 117 Thompson Hall,3367 TAMU, College Stn, TX 77843 USA.
EM alvarado@entc.tamu.edu
OI Alvarado, Jorge/0000-0002-4059-6588
FU Army Corps Engineers Engineer and Research Development Center and
Construction Engineering Research Laboratory; Naval Research Laboratory
FX This work was supported in part by the Army Corps Engineers Engineer and
Research Development Center and Construction Engineering Research
Laboratory, and the Naval Research Laboratory. The authors would also
like to thank Satyanarayana Kondle for his support and knowledge of
Fluent.
NR 23
TC 14
Z9 14
U1 1
U2 5
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
SN 1040-7782
J9 NUMER HEAT TR A-APPL
JI Numer. Heat Tranf. A-Appl.
PY 2009
VL 55
IS 8
BP 721
EP 738
AR PII 910344601
DI 10.1080/10407780902864672
PG 18
WC Thermodynamics; Mechanics
SC Thermodynamics; Mechanics
GA 435UT
UT WOS:000265369500001
ER
PT S
AU Karadogan, E
Willson, CS
Berger, CR
AF Karadogan, E.
Willson, C. S.
Berger, C. R.
GP IEEE
TI Numerical Modeling of the Lower Mississippi River-Influence of Forcings
on Flow Distribution and Impact of Sea Level Rise on the System
SO OCEANS 2009, VOLS 1-3
SE OCEANS-IEEE
LA English
DT Proceedings Paper
CT Oceans 2009 Conference
CY OCT 26-29, 2009
CL Biloxi, MS
SP Marine Technol Soc, IEEE Ocean Engn Soc
AB The Mississippi River, with one of the world's largest watersheds draining 41% of the continental U.S., is the seventh largest river in the world. The lower Mississippi River delta system along the northern Gulf of Mexico coast experiences annual coastal marsh losses between 25 and 35 square miles. The lower River is a highly complex system impacted by multiple forcings. An understanding of the hydrodynamics in this system will be important for understanding the potential outcomes of coastal restoration projects such as large-scale River diversions and for future management decisions. This study describes the development and application of a hydrodynamic model of a reach of the Lower Mississippi River from Carrolton (New Orleans) at RM 103 down to the Gulf of Mexico. The USACE Adaptive Hydraulics Model (ADH), an unstructured finite element model, is used to model the hydrodynamics. An unstructured mesh was developed for the study area, which includes detailed bathymetry and topography from the most recent available survey data. The mesh is fine enough to capture the changes in bathymetry and relies upon automated mesh refinement to capture flow details. Mississippi River stage data collected from thirteen stations between Carrolton and Port Eads for the water years between 1987 and 2008 is used in the model calibration. In addition, discharge data collected in various Lower River passes is used to examine the ability of the hydrodynamic model to properly simulate the flow distribution through different reaches and lower River passes. Steady state solutions for water surface elevations at gage locations match well with observational data and the distribution of river flow among the different sections of river channel and passes are consistent with the limited field data available. The effect of the sea level rise is most significant in the lower 20 miles of the river and it loses its effect with increasing flow rates.
C1 [Karadogan, E.; Willson, C. S.] Louisiana State Univ, Dept Civil & Environm Engn, Baton Rouge, LA 70803 USA.
[Berger, C. R.] US Army, Engn Res & Dev Ctr, Coastal & Hydraul Lab, Vicksburg, MS 39180 USA.
RP Karadogan, E (reprint author), Louisiana State Univ, Dept Civil & Environm Engn, Baton Rouge, LA 70803 USA.
FU Louisiana Office of Coastal Protection and Restoration (OCPR); Coastal
and Hydraulic s Laboratory at the USACE Engineer Research and
Development Center; computational staff of Louisiana State University
Center for Computation and Technology; Louisiana Optical Network
Initiative (LONI); Coastal Environmental Modeling Laboratory (CEML)
FX This study is conducted by the fund supplied by Louisiana Office of
Coastal Protection and Restoration (OCPR) and in collaboration with
Coastal and Hydraulic s Laboratory at the USACE Engineer Research and
Development Center. The computational staff of Louisiana State
University Center for Computation and Technology, The Louisiana Optical
Network Initiative (LONI) and Coastal Environmental Modeling Laboratory
(CEML) provided extensive computational resources and support.
NR 18
TC 0
Z9 0
U1 0
U2 5
PU IEEE
PI NEW YORK
PA 345 E 47TH ST, NEW YORK, NY 10017 USA
SN 0197-7385
BN 978-1-4244-4960-6
J9 OCEANS-IEEE
PY 2009
BP 1531
EP +
PG 2
WC Engineering, Ocean; Oceanography; Remote Sensing
SC Engineering; Oceanography; Remote Sensing
GA BPY34
UT WOS:000280322600224
ER
PT S
AU Macon, CL
AF Macon, C. L.
GP IEEE
TI USACE National Coastal Mapping Program and the Next Generation of Data
Products
SO OCEANS 2009, VOLS 1-3
SE OCEANS-IEEE
LA English
DT Proceedings Paper
CT Oceans 2009 Conference
CY OCT 26-29, 2009
CL Biloxi, MS
SP Marine Technol Soc, IEEE Ocean Engn Soc
AB The U.S. Army Corps of Engineers (USACE) has been monitoring coastal change for decades. Each coastal district has the duty to maintain the federal navigation channels to insure safe passage for commercial and private vessels. In addition to these navigation channels, monitoring coastal change and regional sediment management rank high in both importance and financial expenditures. Acoustic boat surveys have been and will continue to be a viable way to accomplish these goals. For the past 15 years these surveys efforts have been assisted by the Joint Airborne Lidar Bathymetry Technical Center of eXpertise (JALBTCX). The JALBTCX has in-house survey capability using the U.S. Naval Oceanographic Office's Compact Hydrographic Airborne Rapid Total Survey (CHARTS) system. The CHARTS system collects bathymetric lidar, topographic lidar, RGB imagery, and hyperspectral imagery. CHARTS is mounted on a Beech King Air 200 which provides a platform capable of surveying the federal navigation projects and the areas between to support regional sediment management.
In 2004, USACE Headquarters funded JALBTCX to map the sandy shoreline of the continental U.S. on a recurring basis. This mapping effort falls under the National Coastal Mapping Program (NCMP). In addition to the NCMP, JALBTCX performs emergency response surveys following natural disasters. Since 2004, JALBTCX was surveyed after every category 2 (or greater) hurricane that makes land fall within the U.S. As the survey capabilities increase it becomes more difficult for the local engineers to process the large volumes of data and the demand for analysis ready products became a necessity. JALBTCX took on this challenge and is currently delivering a suite of products to meet the needs. With the addition of new sensors, JALBTCX has also been able to develop new data fusion products to assist in monitoring the engineering, economic, and environmental changes to the coastal zone.
C1 USA, Corps Engineers Mobile Dist, Joint Airborne Lidar Bathymetry Tech Ctr eXperits, Kiln, MS 39556 USA.
RP Macon, CL (reprint author), USA, Corps Engineers Mobile Dist, Joint Airborne Lidar Bathymetry Tech Ctr eXperits, 7225 Stennis Airport Rd,Suite100, Kiln, MS 39556 USA.
NR 7
TC 0
Z9 0
U1 0
U2 1
PU IEEE
PI NEW YORK
PA 345 E 47TH ST, NEW YORK, NY 10017 USA
SN 0197-7385
BN 978-1-4244-4960-6
J9 OCEANS-IEEE
PY 2009
BP 1592
EP 1598
PG 7
WC Engineering, Ocean; Oceanography; Remote Sensing
SC Engineering; Oceanography; Remote Sensing
GA BPY34
UT WOS:000280322600232
ER
PT S
AU Casper, AF
Steimle, ET
Hall, ML
Dixon, B
AF Casper, A. F.
Steimle, E. T.
Hall, M. L.
Dixon, B.
GP IEEE
TI Combined GIS and ROV technologies improve characterization of water
quality in Coastal Rivers of the Gulf of Mexico
SO OCEANS 2009, VOLS 1-3
SE OCEANS-IEEE
LA English
DT Proceedings Paper
CT Oceans 2009 Conference
CY OCT 26-29, 2009
CL Biloxi, MS
SP Marine Technol Soc, IEEE Ocean Engn Soc
ID AUTONOMOUS UNDERWATER VEHICLES; ST-LAWRENCE-RIVER; VARIABILITY;
GROUNDWATER; DESIGN; TRENDS; TIME
AB Rivers, estuaries, reservoirs, and lakes are multi-use systems that supply water for agricultural, industrial, and human consumption while simultaneously assimilating both point- and non-point source discharges. Existing methods of data collection are generally limited to snapshots in space and time while a comprehensive view of spatial variability remains elusive. Accelerating the integration of existing in-situ sensors, geospatial analysis techniques, and reliable autonomous sampling platform technologies provide immediate improvements for sampling and assessment programs. We provide a demonstration of this integration for high spatial resolution sampling and analysis in a non-wadeable river with an inexpensive unmanned sampling platform (USV), standards sensor arrays, and widely used geospatial techniques. These are used to creating 2-D maps of temperature, conductivity, salinity, turbidity, chlorophyll florescence and chromophoric dissolved organic matter (CDOM). 2-D surface water quality maps show significant influences on local water quality from tributary confluences, submarine groundwater plumes, floodplain/riparian interfaces and other patchily distributed limnological features. Moreover, this project demonstrates how sensors, autonomous vehicles, and geospatial technologies work in concert to create a more comprehensive spatial picture compared to the standard systematic sampling grid with data displayed as means and standard deviations.
C1 [Steimle, E. T.; Hall, M. L.] AEOS, 1040 17th Ave S, St Petersburg, FL 33704 USA.
[Casper, A. F.; Steimle, E. T.; Dixon, B.] ERDC Environm Lab, Aquat Ecol & Invas Species Branch, Vicksburg, MS USA.
[Casper, A. F.; Dixon, B.] Univ S Florida, Policy & Geog Program, Environm Sci, St Petersburg, FL USA.
[Dixon, B.] Univ S Florida, Geo Spatial Analyt Lab, St Petersburg, FL USA.
RP Steimle, ET (reprint author), AEOS, 1040 17th Ave S, St Petersburg, FL 33704 USA.
EM esteimle@aeosciences.com
FU USEPA-ORD through the U. of South Florida St. Petersburg's Center for
Science; Policy in the Coastal Environment
FX This research was funded by USEPA-ORD through the U. of South Florida
St. Petersburgs Center for Science and Policy in the Coastal
Environment.
NR 32
TC 0
Z9 0
U1 0
U2 3
PU IEEE
PI NEW YORK
PA 345 E 47TH ST, NEW YORK, NY 10017 USA
SN 0197-7385
BN 978-1-4244-4960-6
J9 OCEANS-IEEE
PY 2009
BP 2555
EP +
PG 3
WC Engineering, Ocean; Oceanography; Remote Sensing
SC Engineering; Oceanography; Remote Sensing
GA BPY34
UT WOS:000280322601103
ER
PT B
AU Okusaga, O
Zhou, WM
Carter, G
Menyuk, C
AF Okusaga, Olukayode
Zhou, Weimin
Carter, Gary
Menyuk, Curtis
GP IEEE
TI Investigating the Forward and Backward Injections of Injection-Locked
Dual Optoelectronic Oscillators
SO OFC: 2009 CONFERENCE ON OPTICAL FIBER COMMUNICATION, VOLS 1-5
LA English
DT Proceedings Paper
CT Conference on Optical Fiber Communication (OFC 2009)
CY MAR 22-26, 2009
CL San Diego, CA
AB An injection-locked optoelectronic oscillator (OEO) is investigated for the effects of simultaneous forward and reverse injections between the master and slave OEOs to find the optimized condition for low phase noise and spurious levels.
C1 [Okusaga, Olukayode; Zhou, Weimin] USA, Res Lab, Adelphi, MD 20783 USA.
[Okusaga, Olukayode; Carter, Gary; Menyuk, Curtis] UMBC, Baltimore 21250, MD USA.
RP Okusaga, O (reprint author), USA, Res Lab, Adelphi, MD 20783 USA.
EM Okusaga1@umbc.edu
NR 5
TC 0
Z9 0
U1 0
U2 0
PU IEEE
PI NEW YORK
PA 345 E 47TH ST, NEW YORK, NY 10017 USA
BN 978-1-4244-2606-5
PY 2009
BP 432
EP +
PG 2
WC Engineering, Electrical & Electronic; Optics; Telecommunications
SC Engineering; Optics; Telecommunications
GA BNJ83
UT WOS:000274764200144
ER
PT J
AU DeMartelaere, SL
Perman, KI
Shore, JW
AF DeMartelaere, Sheri L.
Perman, Kevin I.
Shore, John W.
TI Reply re: "Orbital Septal Resection and the Hanging Curtain of Fat"
SO OPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY
LA English
DT Letter
C1 [DeMartelaere, Sheri L.] Brooke Army Med Ctr, MCHE SDO, Ft Sam Houston, TX 78234 USA.
RP DeMartelaere, SL (reprint author), Brooke Army Med Ctr, MCHE SDO, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA.
EM sheri.l.demartelaere@us.army.mil
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0740-9303
J9 OPHTHAL PLAST RECONS
JI Ophthalmic Plast. Reconstr. Surg.
PD JAN-FEB
PY 2009
VL 25
IS 1
BP 77
EP 77
PG 1
WC Ophthalmology; Surgery
SC Ophthalmology; Surgery
GA 398LR
UT WOS:000262734100033
ER
PT S
AU Rivamonte, A
AF Rivamonte, Andre
BE Manns, F
Soderberg, PG
Ho, A
TI Bottlenose dolphin iris asymmetries enhance aerial and underwater vision
SO OPHTHALMIC TECHNOLOGIES XIX
SE Proceedings of SPIE
LA English
DT Proceedings Paper
CT Conference on Ophthalmic Technologies XIX
CY JAN 24-26, 2009
CL San Jose, CA
SP SPIE, Pascal Rol Fdn, Topcon Adv BioMed Imaging Lab
DE bioacoustic imaging; iris asymmetries; operculum; cetaceans; bifocal
lens
ID EYE; ACUITY; PUPIL
AB When the iris of the Bottlenose dolphin (Tursiops truncatus) contracts it constrains the path of light that can focus onto the two areas of the retina having a finer retinal mosaic. Under high ambient light conditions the operculum of the iris shields the lens and forms in the process two asymmetrically shaped, sized and positioned slit pupils. Tracing rays of light in the reverse direction through the pupils from the retinal regions associated with higher resolution confirm behaviorally observed preferred aerial and underwater viewing directions. In the forward and downward viewing direction, the larger temporal pupil admits light that is focused by the weakly refractive margin of a bifocal lens onto the temporal area centralis compensating for the addition of the optically strong front surface of the cornea in air. A schematic dolphin eye model incorporating a bifocal lens offers an explanation for a dolphin's comparable visual acuities in air and water for both high and low ambient light conditions. Comparison of methods for curve fitting psychometric ogive functions to behavioral visual acuity and spectral sensitivity data are discussed.
C1 USA, EALD Engn Div, TMDE Act, Redstone Arsenal, AL 35898 USA.
RP Rivamonte, A (reprint author), USA, EALD Engn Div, TMDE Act, Redstone Arsenal, AL 35898 USA.
NR 35
TC 0
Z9 0
U1 1
U2 6
PU SPIE-INT SOC OPTICAL ENGINEERING
PI BELLINGHAM
PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
SN 0277-786X
BN 978-0-8194-7409-4
J9 PROC SPIE
PY 2009
VL 7163
AR 716321
DI 10.1117/12.804433
PG 9
WC Ophthalmology; Optics; Physics, Applied; Radiology, Nuclear Medicine &
Medical Imaging
SC Ophthalmology; Optics; Physics; Radiology, Nuclear Medicine & Medical
Imaging
GA BSL16
UT WOS:000284821000045
ER
PT J
AU Henderson, D
Smith, JC
AF Henderson, Dale
Smith, J. Cole
TI An exact reformulation-linearisation technique algorithm for solving a
parameter extraction problem arising in compact thermal models
SO OPTIMIZATION METHODS & SOFTWARE
LA English
DT Article
DE branch-and-bound; computation; compact thermal models; nonlinear
optimisation
ID LINEAR-PROGRAMMING PROBLEMS; OPTIMIZATION; PACKAGE; DELPHI; WORLD
AB Compact thermal models (CTMs) are used to evaluate thermal characteristics of critical electronic chip packages under several hypothetical design and usage scenarios. In order to ensure that CTMs accurately estimate thermal response, an appropriate set of model parameters must first be selected. The challenge arising in this paper is to glean a set of parameters that best describes the performance of CTM over a set of test conditions. We examine a non-convex optimisation formulation for this parameter estimation problem, and derive the first exact optimisation algorithm for the problem using a continuous version of the reformulation-linearisation technique. We provide experimental results on real data to demonstrate the applicability of our approach.
C1 [Smith, J. Cole] Univ Florida, Dept Ind & Syst Engn, Gainesville, FL 32611 USA.
[Henderson, Dale] US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA.
RP Smith, JC (reprint author), Univ Florida, Dept Ind & Syst Engn, Gainesville, FL 32611 USA.
EM cole@ise.ufl.edu
FU Air Force Office of Scientific Research [FA9550-08-1-0189]
FX The authors gratefully acknowledge the comments made by two referees,
which helped to improve our paper. Dr. Smith gratefully acknowledges the
support of the Air Force Office of Scientific Research under Grant
#FA9550-08-1-0189.
NR 30
TC 1
Z9 1
U1 0
U2 1
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
SN 1055-6788
J9 OPTIM METHOD SOFTW
JI Optim. Method Softw.
PY 2009
VL 24
IS 4-5
BP 857
EP 870
AR PII 909790290
DI 10.1080/10556780802616924
PG 14
WC Computer Science, Software Engineering; Operations Research & Management
Science; Mathematics, Applied
SC Computer Science; Operations Research & Management Science; Mathematics
GA 481IM
UT WOS:000268801200020
ER
PT J
AU Wipf, P
Mo, TT
Geib, SJ
Caridha, D
Dow, GS
Gerena, L
Roncal, N
Milner, EE
AF Wipf, Peter
Mo, Tingting
Geib, Steven J.
Caridha, Diana
Dow, Geoffrey S.
Gerena, Lucia
Roncal, Norma
Milner, Erin E.
TI Synthesis and biological evaluation of the first pentafluorosulfanyl
analogs of mefloquine
SO ORGANIC & BIOMOLECULAR CHEMISTRY
LA English
DT Article
ID HIGH YIELDING SYNTHESIS; ANTIMALARIAL ACTIVITY; MEDICINAL CHEMISTRY;
P-GLYCOPROTEIN; FLUORINE; MALARIA; PENTAFLUORIDE; RESISTANCE; AGENTS
AB Two novel SF(5) analogs of the antimalarial agent mefloquine were synthesized in 5 steps and 10-23% overall yields and found to have improved activity and selectivity against malaria parasites. This work also represents the first report of SF(5)-substituted quinolines.
C1 [Wipf, Peter; Mo, Tingting; Geib, Steven J.] Univ Pittsburgh, Dept Chem, Pittsburgh, PA 15260 USA.
[Wipf, Peter; Mo, Tingting] Univ Pittsburgh, Ctr Chem Methodol & Lib Dev, Pittsburgh, PA 15260 USA.
[Caridha, Diana; Dow, Geoffrey S.; Gerena, Lucia; Roncal, Norma; Milner, Erin E.] Walter Reed Army Inst Res, Div Expt Therapeut, Silver Spring, MD 20910 USA.
RP Wipf, P (reprint author), Univ Pittsburgh, Dept Chem, Pittsburgh, PA 15260 USA.
EM pwipf@pitt.edu; geoffrey.dow@us.army.mil
FU NIGMS NIH HHS [P50 GM067082-07, P50 GM067082]
NR 39
TC 57
Z9 57
U1 2
U2 23
PU ROYAL SOC CHEMISTRY
PI CAMBRIDGE
PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS,
ENGLAND
SN 1477-0520
J9 ORG BIOMOL CHEM
JI Org. Biomol. Chem.
PY 2009
VL 7
IS 20
BP 4163
EP 4165
DI 10.1039/b911483a
PG 3
WC Chemistry, Organic
SC Chemistry
GA 500QZ
UT WOS:000270320300003
PM 19795052
ER
PT J
AU Banks, HD
AF Banks, Harold D.
TI Is nucleophilic cleavage chemistry practical for 4-membered
heterocycles?
SO ORGANIC & BIOMOLECULAR CHEMISTRY
LA English
DT Article
ID SUBSTITUTION REACTIONS; AZETIDINE DERIVATIVES; SOLVATION MODELS;
AB-INITIO; OXETANES; ACID; REACTIVITY; REGIOSELECTIVITY; AZIRIDINES;
ALCOHOLS
AB A computational study at the MP2(Full)/6-311++G(d,p)//MP2(Full)/6-31+G(d) level of the ammonolysis of halogen substituted azetidines, oxetanes and thietanes was performed in the gas phase and in the commonly used solvent, acetonitrile. Using the free energy of activation of a benchmark reaction for evaluation of synthetic viability, several haloazetidines and oxetanes that possessed the required reactivity were identified; however, no substituted thietane investigated herein was determined to be synthetically useful under the mild conditions selected for this study. In the case of the azetidines, the side reaction of displacement of halide ion was determined to be the preferred reaction course in acetonitrile; however, the amino product of the reactions of the 2-haloazetidines cleaved at an acceptable rate under mild conditions. For the oxetane derivatives investigated, 2-fluorooxetane proved to be a direct source of ring cleavage product. Nucleophilic cleavage of halogen-substituted azetidines and oxetanes is predicted to be a viable source of functionalized three-carbon moieties under mild conditions in organic synthesis.
C1 USA, Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD 21010 USA.
RP Banks, HD (reprint author), USA, Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD 21010 USA.
EM harold.banks@us.army.mil
NR 53
TC 3
Z9 3
U1 2
U2 8
PU ROYAL SOC CHEMISTRY
PI CAMBRIDGE
PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS,
ENGLAND
SN 1477-0520
J9 ORG BIOMOL CHEM
JI Org. Biomol. Chem.
PY 2009
VL 7
IS 21
BP 4496
EP 4501
DI 10.1039/b908861j
PG 6
WC Chemistry, Organic
SC Chemistry
GA 506SH
UT WOS:000270795700023
PM 19830301
ER
PT J
AU Keefe, MA
Castro, JR
Keefe, MS
AF Keefe, Michael A.
Castro, Jerry R.
Keefe, Morgan S.
TI Identification of the facial nerve main trunk by retrograde dissection
of the postauricular branch
SO OTOLARYNGOLOGY-HEAD AND NECK SURGERY
LA English
DT Article
C1 [Keefe, Michael A.] Sharp Mem Hosp & Rehabil Ctr, Div Head & Neck Surg, Sharp Rees Stealy Med Grp, San Diego, CA 92131 USA.
[Keefe, Michael A.] Naval Med Ctr San Diego, San Diego, CA 92131 USA.
[Castro, Jerry R.] Walter Reed Army Med Ctr, Natl Capitol Consortium, Dept Head & Neck Surg, Washington, DC 20307 USA.
[Keefe, Morgan S.] Acad Our Lady Peace, San Diego, CA USA.
RP Keefe, MA (reprint author), Sharp Mem Hosp & Rehabil Ctr, Div Head & Neck Surg, Sharp Rees Stealy Med Grp, 10670 Wexlord St, San Diego, CA 92131 USA.
EM Michael.KeefeMD@Sharp.Com
NR 3
TC 3
Z9 3
U1 0
U2 1
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0194-5998
J9 OTOLARYNG HEAD NECK
JI Otolaryngol. Head Neck Surg.
PD JAN
PY 2009
VL 140
IS 1
BP 126
EP 127
DI 10.1016/j.otohns.2008.10.014
PG 2
WC Otorhinolaryngology; Surgery
SC Otorhinolaryngology; Surgery
GA 394PD
UT WOS:000262458100026
PM 19130976
ER
PT J
AU Bochicchio, C
Fletcher, C
Dyer, M
Smith, T
AF Bochicchio, Christopher
Fletcher, Charles
Dyer, Matthew
Smith, Thomas
TI Reef-Top Sediment Bodies: Windward O'ahu, Hawai'i
SO PACIFIC SCIENCE
LA English
DT Article
ID KAILUA BAY; SUBMARINE; HISTORY
AB Hawaiian fringing reefs display sand bodies on their surfaces that are potentially important components of littoral sediment budgets. This work provides a regional survey of modern reef-top sediment storage and investigated geologic controls on sediment storage potential. Sand bodies are formed when sediment accumulates in topographic depressions that are the result of meteoric water eroding the emerged carbonate reef platform during periods of lower sea level. The relief of some depressions may be modified by Holocene reef accretion. Depression morphology exerts a strong control on volume and internal distribution of sediment. In this study a total of 205 jet probe thickness measurements was collected from 54 major sand bodies on the fringing reef (0-20 in depth) adjacent to 22 km of Southeast O'ahu coastline (Kailua, Lanikai, and Waimanalo). Volumes were determined and synthesized with previous volume estimates of coastal subaerial and deeper submarine sediment bodies (20-200 m depth), giving the total sediment storage within the coastal system. Sand bodies range from 50 to 2,800 in from shore. Measured thickness varied from 0 to greater than 3.0 m with a mean of 0.95 m. For this study sand bodies were classified into three dominate morphologies: channel, field, and karst depression. The volume of sediment stored in channels was 58,253 +/- 618 x 10(3) m(3), fields contained 171 +/- 6 x 10(3) m(3), and karst depressions contained 1,332 +/- 248 x 10(3) m(3). Correlation of sediment body distribution with reef and coastal plain morphology revealed potential geologic controls on sand body formation in this region. Meteoric runoff and reef slope are important controls on spatial distribution of sand bodies.
C1 [Bochicchio, Christopher; Fletcher, Charles; Dyer, Matthew] Univ Hawaii Manoa Coastal Geol, Dept Geol & Geophys, Honolulu, HI 96822 USA.
[Smith, Thomas] USA, Corps Engineers, Pacific Ocean Div, Ft Shafter, HI 96858 USA.
RP Bochicchio, C (reprint author), Univ Hawaii Manoa Coastal Geol, Dept Geol & Geophys, 1680 East West Rd,Post 721A, Honolulu, HI 96822 USA.
EM bochicch@hawaii.edu
FU U.S. Army Corps. of Engineers; U.S. Geological Survey; Hawai'i
Department of Land and Natural Resources
FX We thank the U.S. Army Corps. of Engineers, U.S. Geological Survey, and
the Hawai'i Department of Land and Natural Resources for providing
funding for this project.
NR 34
TC 7
Z9 7
U1 3
U2 4
PU UNIV HAWAII PRESS
PI HONOLULU
PA 2840 KOLOWALU ST, HONOLULU, HI 96822 USA
SN 0030-8870
J9 PAC SCI
JI Pac. Sci.
PD JAN
PY 2009
VL 63
IS 1
BP 61
EP 82
DI 10.2984/1534-6188(2009)63[61:RSBWOH]2.0.CO;2
PG 22
WC Marine & Freshwater Biology; Zoology
SC Marine & Freshwater Biology; Zoology
GA 361YQ
UT WOS:000260164500005
ER
PT S
AU Hoover, JJ
Turnage, A
Killgore, KJ
AF Hoover, Jan Jeffrey
Turnage, April
Killgore, K. Jack
BE Paukert, CP
Scholten, GD
TI Swimming Performance of Juvenile Paddlefish: Quantifying Risk of
Entrainment
SO PADDLEFISH MANAGEMENT, PROPAGATION, AND CONSERVATION IN THE 21ST
CENTURY: BUILDING FROM 20 YEARS OF RESEARCH AND MANAGEMENT
SE American Fisheries Society Symposium
LA English
DT Proceedings Paper
CT Symposium on Paddlefish Conservation and Management
CY DEC 05, 2006
CL Omaha, NE
SP Amer Fisheries Soc
ID POLYODON-SPATHULA; FISH; VENTILATION; STURGEON; TESTS
AB Rheotaxis, endurance, and behavior of juvenile paddlefish Polyodon spathula (<115 mm eye-to-fork length) were measured in a laboratory swim tunnel. Paddlefish were positively rheotactic (>80% of individuals tested). They exhibited sustained swimming (>= 200 min) at water velocities up to 40 cm/s, prolonged swimming (0.5-52 min) at 30-50 cm/s, and burst swimming (<0.5 min) at water velocities 60-75 cm/s. Behavior consisted exclusively of free swimming in the water column. Fish recovered from white spot Ichthy-ophthirius multifiliis disease appeared healthy but had reduced endurance at low to moderate water velocities. Data were used to quantify risk of entrainment by dredges at a given water velocity as an index, values of which ranged from 0.00 (unlikely) to 1.00 (inevitable). Entrainment risk was evaluated for escape speeds considered environmentally conservative (based on prolonged swim speed) and operationally conservative (based on burst swim speed), using flow field models of three cutterhead dredges having pipe diameters of 71, 51, and 30 cm. Entrainment was likely within a radius of 1.25 m of the cutterhead, but degree of risk and distance of entraining flow varied substantially with pipe size. Entrainment risk of paddlefish can be reduced by (1) temporal restrictions on dredging, (2) stocking juveniles that have not been treated for disease, and (3) use of small diameter pipes (ideally <30 cm).
C1 [Hoover, Jan Jeffrey; Turnage, April; Killgore, K. Jack] USA, Engineer Res & Dev Ctr, Waterways Expt Stn, Vicksburg, MS 39180 USA.
RP Hoover, JJ (reprint author), USA, Engineer Res & Dev Ctr, Waterways Expt Stn, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA.
EM jan.j.hoover@usace.army.mil
NR 39
TC 8
Z9 8
U1 0
U2 6
PU AMER FISHERIES SOC
PI BETHESDA
PA 5410 GROSVENOR LANE, STE 110, BETHESDA, MD 20814-2199 USA
SN 0892-2284
BN 978-1-934874-12-7
J9 AM FISH S S
PY 2009
VL 66
BP 141
EP 155
PG 15
WC Fisheries
SC Fisheries
GA BPB75
UT WOS:000278471300009
ER
PT S
AU Hoover, JJ
Boysen, KA
Murphy, CE
George, SG
AF Hoover, Jan Jeffrey
Boysen, Krista A.
Murphy, Catherine E.
George, Steven G.
BE Paukert, CP
Scholten, GD
TI Morphological Variation in Juvenile Paddlefish
SO PADDLEFISH MANAGEMENT, PROPAGATION, AND CONSERVATION IN THE 21ST
CENTURY: BUILDING FROM 20 YEARS OF RESEARCH AND MANAGEMENT
SE American Fisheries Society Symposium
LA English
DT Proceedings Paper
CT Symposium on Paddlefish Conservation and Management
CY DEC 05, 2006
CL Omaha, NE
SP Amer Fisheries Soc
ID LOWER MISSISSIPPI RIVER; POLYODON-SPATHULA; CYPRINELLA-VENUSTA;
BLACKTAIL SHINER; ACIPENSERIFORMES; VENTILATION; VERTEBRATES;
LOCOMOTION; STURGEONS; FINS
AB Juvenile paddlefish Polyodon spat hula exhibit conspicuous variation in the shape of their rostra and caudal fins. We quantified morphological variation for a composite collection of young-of-year paddlefish (N = 55; 61.9-403.7 mm total length) using nine measurements of the rostrum, body, and caudal fin. Sheared principal component analysis of morphological data resulted in three distinct groups of fish corresponding to three different localities: hatchery-reared fish from the Mermentau River, Louisiana; hatchery-reared fish from the Tombigbee River, Alabama; and field-collected fish from the Mississippi River, Mississippi. Series were segregated from each other based on size of caudal lobes and width of rostrum. With increased body size of fish, relative length of rostrum increased, and mesal expansion of rostrum increased for all three series. For Tombigbee and Mississippi River series, with increased size of fish, caudal asymmetry decreased. Overall, smaller fish had shorter, narrower rostra and highly asymmetrical caudal lobes; larger fish had longer, broader rostra and more symmetrical caudal lobes. Morphological differences among series were most conspicuous for fish greater than 85 mm eye-to-fork length. Fish from Mermentau River had shorter, narrower (leaf-shaped) rostra and asymmetrical (conspicuously heterocercal) caudal lobes. Those from the Tombigbee River had longer, broader (spoon-shaped) rostra and more symmetrical caudal lobes. Those from the Mississippi River had the longest, broadest (paddle-shaped) rostra and symmetrical (superficially "homocercal") caudal lobes. Locality-based gradient in paddlefish morphology corresponds to a gradient in river hydrology: longer, broader rostra and symmetrical caudal lobes were associated with larger basins, higher gradients, and greater discharge.
C1 [Hoover, Jan Jeffrey; Boysen, Krista A.; Murphy, Catherine E.; George, Steven G.] USA, Engineer Res & Dev Ctr, Waterways Expt Stn, Vicksburg, MS 39180 USA.
RP Hoover, JJ (reprint author), USA, Engineer Res & Dev Ctr, Waterways Expt Stn, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA.
EM jan.j.hoover@usace.army.mil
NR 44
TC 3
Z9 3
U1 1
U2 2
PU AMER FISHERIES SOC
PI BETHESDA
PA 5410 GROSVENOR LANE, STE 110, BETHESDA, MD 20814-2199 USA
SN 0892-2284
BN 978-1-934874-12-7
J9 AM FISH S S
PY 2009
VL 66
BP 157
EP 171
PG 15
WC Fisheries
SC Fisheries
GA BPB75
UT WOS:000278471300010
ER
PT J
AU Cohen, SP
Dragovich, A
Larkin, TM
AF Cohen, Steven P.
Dragovich, Anthony
Larkin, Thomas M.
TI Dehydration: Cause of Acute Renal Failure RESPONSE
SO PAIN PHYSICIAN
LA English
DT Letter
ID EVENTS
C1 [Cohen, Steven P.] Johns Hopkins Sch Med, Baltimore, MD 20205 USA.
[Cohen, Steven P.; Dragovich, Anthony] Walter Reed Army Med Ctr, Washington, DC 20307 USA.
[Dragovich, Anthony] Womack Army Med Ctr, Ft Bragg, NC 28307 USA.
[Larkin, Thomas M.] Pkwy Neurosci & Spine Inst, Hagerstown, MD 21740 USA.
RP Cohen, SP (reprint author), Johns Hopkins Sch Med, Baltimore, MD 20205 USA.
EM scohen40@jhmi.edu; larkintm@comcast.net
NR 8
TC 0
Z9 0
U1 0
U2 0
PU AM SOC INTERVENTIONAL PAIN PHYSICIANS
PI PADUCAH
PA 81 LAKEVIEW DR, PADUCAH, KY 42001 USA
SN 1533-3159
J9 PAIN PHYSICIAN
JI Pain Physician
PD JAN-FEB
PY 2009
VL 12
IS 1
BP 282
EP 282
PG 1
WC Anesthesiology; Clinical Neurology
SC Anesthesiology; Neurosciences & Neurology
GA 406SC
UT WOS:000263314200016
ER
PT J
AU Lee, JK
Grace, KA
Taylor, AJ
AF Lee, Jeannie K.
Grace, Karen A.
Taylor, Allen J.
TI Ten lessons learned from conducting an adherence intervention trial
SO PATIENT PREFERENCE AND ADHERENCE
LA English
DT Article
DE adherence; pharmacist; intervention; medication
AB Clinical practice research provides a unique opportunity to care for a diverse patient population in various health care system settings. Federal study of Adherence to Medications in the Elderly (FAME) was the first prospective observational and randomized controlled trial to implement effective strategies to enhance medication adherence and health outcomes in older patients using polypharmacy. Ten lessons learned from conducting this adherence intervention trial are described: (1) Link the trial to existing clinical work, (2) Begin with a thorough understanding of medication adherence, (3) Ensure that trial highlights individualized intervention, (4) Tailor inclusion criteria and study duration to target population, (5) Employ a range of outcomes linked to meaningful clinical effects, (6) Win the support of the multidisciplinary team and the administration, (7) Promote team work, (8) Consider the potential limitations, (9) Seize the grant opportunities, and (10) Share the findings.
C1 [Lee, Jeannie K.] Univ Arizona, Coll Pharm, Dept Pharm Practice & Sci, Tucson, AZ 85721 USA.
Walter Reed Army Med Ctr, Dept Pharm, Washington, DC 20307 USA.
[Grace, Karen A.; Taylor, Allen J.] Washington Hosp Ctr, Div Cardiol, Washington, DC 20010 USA.
RP Lee, JK (reprint author), Univ Arizona, Coll Pharm, Dept Pharm Practice & Sci, 1295 N Martin Ave,POB 210202, Tucson, AZ 85721 USA.
EM jlee@pharmacy.arizona.edu
NR 19
TC 1
Z9 1
U1 0
U2 3
PU DOVE MEDICAL PRESS LTD
PI ALBANY
PA PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND
SN 1177-889X
J9 PATIENT PREFER ADHER
JI Patient Prefer. Adherence
PY 2009
VL 3
BP 93
EP 98
PG 6
WC Medicine, General & Internal
SC General & Internal Medicine
GA V21NU
UT WOS:000208215100012
PM 19936150
ER
PT B
AU Eastman, R
Hong, T
Shi, J
Hanning, T
Muralikrishnan, B
Young, SS
Chang, T
AF Eastman, Roger
Hong, Tsai
Shi, Jane
Hanning, Tobias
Muralikrishnan, Bala
Young, S. Susan
Chang, Tommy
BE Madhavan, R
Tubstel, E
Messina, E
TI Performance Evaluation and Metrics for Perception in Intelligent
Manufacturing
SO PERFORMANCE EVALUATION AND BENCHMARKING OF INTELLIGENT SYSTEMS
LA English
DT Proceedings Paper
CT Workshop on Performance Metrics for Intelligent Systems (PerMIS 08)
CY AUG 19-21, 2008
CL Natl Inst Stand, Gaithersburg, MD
HO Natl Inst Stand
AB An unsolved but important problem in intelligent manufacturing is dynamic pose estimation under complex environmental conditions-tracking an object's pose and position as it moves in an environment with uncontrolled lighting and back-round. This is a central task in robotic perception, and a robust, highly accurate solution would be of use in a number of manufacturing applications. To be commercially feasible, a solution must also be benchmarked against performance standards so manufacturers fully understand its nature and capabilities. The PerMIS 2008 Special Session on "Performance Metrics for Perception in Intelligent Manufacturing," held August 20, 2008, brought together academic, industrial and governmental researchers interested in calibrating and benchmarking vision and metrology systems. The special session had a series of speakers who each addressed a component of the general problem of benchmarking complex perception tasks, including dynamic pose estimation. The components included assembly line motion analysis, camera calibration, laser tracker calibration, super-resolution range data enhancement and evaluation, and evaluation of 6DOF pose estimation for visual servoing. This Chapter combines and summarizes the results of the special session, giving a framework for benchmarking perception systems and relating the individual components to the general framework.
C1 [Eastman, Roger] Loyola Univ, Baltimore, MD 21210 USA.
[Hong, Tsai; Muralikrishnan, Bala; Chang, Tommy] Natl Inst Stand & Technol, Gaithersburg, MD 20899 USA.
[Shi, Jane] Gen Motors Res & Dev, Warren, MI 48090 USA.
[Hanning, Tobias] Univ Passau, Passau, Germany.
[Young, S. Susan] Army Res Lab, Adelphi, MD 20783 USA.
RP Eastman, R (reprint author), Loyola Univ, Baltimore, MD 21210 USA.
EM reastman@loyola.edu; jane.shi@gm.com
NR 38
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES
BN 978-1-4419-0491-1
PY 2009
BP 269
EP +
DI 10.1007/978-1-4419-0492-8_12
PG 4
WC Computer Science, Artificial Intelligence
SC Computer Science
GA BMM54
UT WOS:000272813500012
ER
PT B
AU Schlenker, BR
Miller, ML
Johnson, RM
AF Schlenker, Barry R.
Miller, Marisa L.
Johnson, Ryan M.
BE Narvaez, D
Lapsley, DK
TI Moral Identity, Integrity, and Personal Responsibility
SO PERSONALITY, IDENTITY, AND CHARACTER: EXPLORATIONS IN MORAL PSYCHOLOGY
LA English
DT Article; Book Chapter
ID TRIANGLE MODEL; SELF; CONCEPTIONS; COMMITMENT; BEHAVIOR; CHARACTER;
JUDGMENT; EXCUSES; IMPACT
C1 [Schlenker, Barry R.; Johnson, Ryan M.] Univ Florida, Gainesville, FL 32611 USA.
[Miller, Marisa L.] USA, Res Inst, Ft Benning, GA USA.
RP Schlenker, BR (reprint author), Univ Florida, Gainesville, FL 32611 USA.
NR 60
TC 11
Z9 11
U1 0
U2 0
PU CAMBRIDGE UNIV PRESS
PI CAMBRIDGE
PA THE PITT BUILDING, TRUMPINGTON ST, CAMBRIDGE CB2 1RP, CAMBS, ENGLAND
BN 978-0-521-71927-8
PY 2009
BP 316
EP 340
DI 10.1017/CBO9780511627125.015
D2 10.1017/CBO9780511627125
PG 25
WC Psychology, Social
SC Psychology
GA BBS96
UT WOS:000308085600015
ER
PT J
AU Durst, HD
Rohrbaugh, DK
Munavalli, S
AF Durst, H. D.
Rohrbaugh, D. K.
Munavalli, S.
TI Microwave-Assisted Reaction of Dimethyl H-Phosphonate with Cyclohexene
and Alkene Oxides
SO PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
LA English
DT Article
DE Butyl and decyl derivatives; cyclohexyl; deoxygenation; diastereomeric
phosphonates and pyrophosphates; dimethyl H-phosphonate; free radical
reaction; mass spectral breakdown behavior
ID ORGANOPHOSPHORUS COMPOUNDS; ORGANIC-SYNTHESIS; STYRENE OXIDE; ARENE
OXIDES; EPOXIDES; CHEMISTRY; OXIDATION; ESTERS; REARRANGEMENT;
ACTIVATION
AB Microwave-assisted reaction of dimethyl H-phosphonate with cyclohexene-, 1,2-butene-, and 1,2-decene oxides furnishes 8, 5, and 17 compounds, respectively. The probable mechanism of the formation of the various compounds via free radical reactions and their GC-MS characterization are presented in this article.
C1 [Munavalli, S.] SAIC, Gunpowder Branch, Aberdeen Proving Ground, MD 21010 USA.
[Durst, H. D.; Rohrbaugh, D. K.] USA, Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD USA.
RP Munavalli, S (reprint author), SAIC, Gunpowder Branch, POB 68, Aberdeen Proving Ground, MD 21010 USA.
EM shekar.munavalli@us.army.mil
NR 64
TC 1
Z9 1
U1 0
U2 5
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
SN 1042-6507
J9 PHOSPHORUS SULFUR
JI Phosphorus Sulfur Silicon Relat. Elem.
PY 2009
VL 184
IS 10
BP 2680
EP 2696
DI 10.1080/10426500802561419
PG 17
WC Chemistry, Inorganic & Nuclear; Chemistry, Organic
SC Chemistry
GA 596MV
UT WOS:000277690200022
ER
PT J
AU Durst, HD
Rohrbaugh, DK
Munavalli, S
AF Durst, H. D.
Rohrbaugh, D. K.
Munavalli, S.
TI Stereoselective Synthesis of Phosphoryl Derivatives
SO PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
LA English
DT Article
DE Alkylphosphinates; dialkylphosphites; mass spectral characterization;
Michaelis-Arbuzov reaction; stereoselectivity
ID H-DIMETHYLPHOSPHONATE; RING PHOSPHITES; ESTERS; STEREOCHEMISTRY;
CHEMISTRY; SALTS
AB The reaction of dialkylphosphonites with N-(bromomethyl) phthalimide furnishes alkyl phenyl hydrogenphosphinates, dialkyl phenylphosphonates, and N[(bromomethyl)phthalimido)]-phosphinates. The stereoselectivity of the primary product of the reaction appears to increase with the increasing size of the groups attached to the phosphorus atom.
C1 [Munavalli, S.] SAIC, Gunpowder Branch, Aberdeen Proving Ground, MD 21010 USA.
[Durst, H. D.; Rohrbaugh, D. K.] USA, Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD USA.
RP Munavalli, S (reprint author), SAIC, Gunpowder Branch, POB 68, Aberdeen Proving Ground, MD 21010 USA.
EM shekar.munavalli@yahoo.com
NR 32
TC 2
Z9 3
U1 0
U2 0
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
SN 1042-6507
J9 PHOSPHORUS SULFUR
JI Phosphorus Sulfur Silicon Relat. Elem.
PY 2009
VL 184
IS 11
BP 2902
EP 2909
DI 10.1080/10426500802591655
PG 8
WC Chemistry, Inorganic & Nuclear; Chemistry, Organic
SC Chemistry
GA 596MZ
UT WOS:000277690600013
ER
PT J
AU Munavalli, S
Rohrbaugh, DK
Durst, HD
AF Munavalli, S.
Rohrbaugh, D. K.
Durst, H. D.
TI Interesting Transformations of Thiocamphor
SO PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
LA English
DT Article
DE GC-MS; mass spectrometry; pathway; radicals
ID THIOCARBONYL COMPOUNDS; THIOKETONES; CONVERSION; MILD
AB Thiocamphor has been found to furnish bornane, camphor, isoborneol, isobornylthiol, bornylthiol, tetrahydro-bis-(1,7,7-trimethylbicyclo[2.2.1]heptyl)-3,3'-disulfide, and three isomeric bis-(1,7,7-trimethylbicyclo[2.2.1]heptyl)-3,3'-dithiols when treated with NaBH(4) either in dry THF or dry diethylene glycol diethyl ether. The origins of the above interesting compounds and their mass spectral characterization are presented in this article.
C1 [Munavalli, S.] Sci Applicat Int Corp, Edgewood, MD 21010 USA.
[Rohrbaugh, D. K.; Durst, H. D.] USA, Edgewood Chem & Biol Ctr, APG, Edgewood, MD USA.
RP Munavalli, S (reprint author), Sci Applicat Int Corp, POB 68, Edgewood, MD 21010 USA.
EM shekar.munavalli@yahoo.com
NR 15
TC 0
Z9 0
U1 2
U2 3
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
SN 1042-6507
J9 PHOSPHORUS SULFUR
JI Phosphorus Sulfur Silicon Relat. Elem.
PY 2009
VL 184
IS 11
BP 2989
EP 2995
DI 10.1080/10426500802625743
PG 7
WC Chemistry, Inorganic & Nuclear; Chemistry, Organic
SC Chemistry
GA 596MZ
UT WOS:000277690600020
ER
PT S
AU Reed, ML
Readinger, ED
Moe, CG
Shen, H
Wraback, M
Syrkin, A
Usikov, A
Kovalenkov, OV
Dmitriev, VA
AF Reed, M. L.
Readinger, E. D.
Moe, C. G.
Shen, H.
Wraback, M.
Syrkin, A.
Usikov, A.
Kovalenkov, O. V.
Dmitriev, V. A.
BE Stutzmann, M
Stolz, H
TI Benefits of negative polarization charge in n-InGaN on p-GaN single
heterostructure light emitting diode with p-side down
SO PHYSICA STATUS SOLIDI C: CURRENT TOPICS IN SOLID STATE PHYSICS, VOL 6,
NO 2
SE Physica Status Solidi C-Current Topics in Solid State Physics
LA English
DT Proceedings Paper
CT 9th International Workshop on Nonlinear Optics and Excitation Kinetics
in Semiconductors
CY MAY 26-29, 2008
CL Klink, GERMANY
ID MULTIPLE-QUANTUM WELLS; FIELDS
AB The effects of negative polarization charge at the n-InGaN/pGaN interface on the performance of hydride vapour phase epitaxy-deposited single heterostructure n-In0.17Ga0.83N/p-GaN light emitting diodes with p-side down are investigated. The negative polarization charge at the interface leads to the formation of a two-dimensional hole gas within the InGaN near the n-InGaN/p-GaN interface, as well as reducing the barrier for hole injection. In addition, electrons encounter experience a significant barrier for injection across the heterointerface. As a result, superlinear increase in light output as injection current increases below 20 A/cm(2) and peak emission wavelength shift from 495 nm to 470 nm are observed. We show that the combination of two-dimensional hole-gas formation on the n-InGaN side of the hetero-interface and enhancement of the electron barrier to transport across this interface may reduce efficiency droop at high current density without the need for an AlGaN electron blocking layer. (C) 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
C1 [Reed, M. L.; Readinger, E. D.; Moe, C. G.; Shen, H.; Wraback, M.] USA, Res Lab, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA.
[Syrkin, A.; Usikov, A.; Kovalenkov, O. V.; Dmitriev, V. A.] Technol & Devices Int Inc, Silver Spring, MD 20904 USA.
RP Reed, ML (reprint author), USA, Res Lab, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA.
EM Meredith.L.Reed@arl.army.mil
FU U.S. Department of Energy Solid State LightingProgram
FX TDI, Inc. gratefully acknowledges the support of the U.S. Department of
Energy Solid State LightingProgram.
NR 15
TC 4
Z9 8
U1 0
U2 6
PU WILEY-V C H VERLAG GMBH
PI WEINHEIM
PA PAPPELALLEE 3, W-69469 WEINHEIM, GERMANY
SN 1862-6351
J9 PHYS STATUS SOLIDI C
PY 2009
VL 6
IS 2
BP 585
EP +
DI 10.1002/pssc.200880401
PG 2
WC Optics; Physics, Applied
SC Optics; Physics
GA BJD25
UT WOS:000264882800049
ER
PT S
AU Garrett, GA
Shen, HE
Wraback, M
Tyagi, A
Schmidt, MC
Speck, JS
DenBaars, SP
Nakamaura, S
AF Garrett, Gregory A.
Shen, Hongen
Wraback, Michael
Tyagi, Anurag
Schmidt, Mathew C.
Speck, James S.
DenBaars, Steven P.
Nakamaura, Shuji
BE Butte, R
TI Comparison of time-resolved photoluminescence from InGaN single quantum
wells grown on nonpolar and semipolar bulk GaN substrates
SO PHYSICA STATUS SOLIDI C: CURRENT TOPICS IN SOLID STATE PHYSICS, VOL 6,
SUPPL 2
SE Physica Status Solidi C-Current Topics in Solid State Physics
LA English
DT Proceedings Paper
CT International Workshop on Nitride Semiconductors
CY OCT 06-10, 2008
CL Montreux, SWITZERLAND
AB Single quantum wells of low InN concentration InGaN grown on high quality nonpolar and semipolar substrates cut from bulk GaN boules are studied by time-resolved photoluminescence techniques. Data is presented for different well widths at varying pump fluence and sample temperature to study nonlinear non-radiative recombination, radiative lifetimes, and carrier localization or separation. (C) 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
C1 [Garrett, Gregory A.; Shen, Hongen; Wraback, Michael] USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
[Tyagi, Anurag; Schmidt, Mathew C.; Speck, James S.; DenBaars, Steven P.; Nakamaura, Shuji] Univ Calif Santa Barbara, Elect & Comp Engn & Mat, Santa Barbara, CA 93106 USA.
RP Garrett, GA (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM gregory.a.garrett@us.army.mil
RI Speck, James/H-5646-2011
NR 5
TC 24
Z9 24
U1 1
U2 11
PU WILEY-V C H VERLAG GMBH
PI WEINHEIM
PA PAPPELALLEE 3, W-69469 WEINHEIM, GERMANY
SN 1862-6351
J9 PHYS STATUS SOLIDI C
PY 2009
VL 6
BP S800
EP S803
DI 10.1002/pssc.200880974
PN S2
PG 4
WC Optics; Physics, Applied; Physics, Condensed Matter
SC Optics; Physics
GA BWQ45
UT WOS:000294494400128
ER
PT S
AU Metcalfe, GD
Readinger, ED
Shen, HE
Woodward, NT
Dierolf, V
Wraback, M
AF Metcalfe, Grace D.
Readinger, Eric D.
Shen, Hongen
Woodward, Nathaniel T.
Dierolf, Volkmar
Wraback, Michael
BE Butte, R
TI Energy levels of Nd3+ ions in GaN
SO PHYSICA STATUS SOLIDI C: CURRENT TOPICS IN SOLID STATE PHYSICS, VOL 6,
SUPPL 2
SE Physica Status Solidi C-Current Topics in Solid State Physics
LA English
DT Proceedings Paper
CT International Workshop on Nitride Semiconductors
CY OCT 06-10, 2008
CL Montreux, SWITZERLAND
ID ROOM-TEMPERATURE; IMPLANTED GAN; DOPED GAN; PHOTOLUMINESCENCE;
SPECTROSCOPY
AB We report the Stark energy sublevels of Nd3+ ions in GaN grown by plasma-assisted molecular beam epitaxy as determined by luminescence spectra. The photoluminescence spectra is correlated with transitions from the F-4(3/2) doublet state to the I-4(9/2), I-4(11/2), and I-4(13/2) multiplets of the Nd3+ ion for above and below bandgap excitation, with the strongest emission occurring at 1.12 eV (1106 nm). A splitting of the F-4(3/2) excited state is determined to be 4.1 meV. From photoluminescence excitation spectra, we also identify the Stark sublevels of the excited states F-4(5/2), H-2(9/2), F-4(7/2), S-4(3/2), (2)G(7/2), and (4)G(5/2). Photoluminescence excitation spectra exhibit an optimal excitation energy of 1.48 eV (836 nm). Site-selective spectroscopy studies using combined excitation-emission spectroscopy with confocal microscopy imply enhanced substantial doping at the Ga site. In addition, optical loss and gain measurements of a GaN:Nd waveguide excited above bandgap indicate an internal loss coefficient of similar to 6.5 +/-2 cm(-1) and a net gain of similar to -2 +/- 2 cm(-1). (C) 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
C1 [Metcalfe, Grace D.; Readinger, Eric D.; Shen, Hongen; Wraback, Michael] USA, Res Lab, Sensors & Electron Devices Directorate, AMSRD ARL SE EM, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
[Woodward, Nathaniel T.; Dierolf, Volkmar] Lehigh Univ, Dept Phys, Bethlehem, PA 18015 USA.
RP Metcalfe, GD (reprint author), USA, Res Lab, Sensors & Electron Devices Directorate, AMSRD ARL SE EM, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM grace.metcalfe@us.army.mil; eric.readinger@us.army.mil
NR 14
TC 2
Z9 2
U1 1
U2 5
PU WILEY-V C H VERLAG GMBH
PI WEINHEIM
PA PAPPELALLEE 3, W-69469 WEINHEIM, GERMANY
SN 1862-6351
J9 PHYS STATUS SOLIDI C
PY 2009
VL 6
BP S671
EP S674
DI 10.1002/pssc.200880953
PN S2
PG 4
WC Optics; Physics, Applied; Physics, Condensed Matter
SC Optics; Physics
GA BWQ45
UT WOS:000294494400096
ER
PT J
AU Podeszwa, R
Rice, BM
Szalewicz, K
AF Podeszwa, Rafal
Rice, Betsy M.
Szalewicz, Krzysztof
TI Crystal structure prediction for cyclotrimethylene trinitramine (RDX)
from first principles
SO PHYSICAL CHEMISTRY CHEMICAL PHYSICS
LA English
DT Article
ID DENSITY-FUNCTIONAL THEORY; POTENTIAL-ENERGY SURFACE; AB-INITIO;
PENTAERYTHRITOL TETRANITRATE; BENZENE DIMER; HMX
AB Crystal structure prediction and molecular dynamics methods were applied to the cyclotrimethylene trinitramine (RDX) crystal to explore the stability rankings of various polymorphs using a recently developed nonempirical potential energy function that describes the RDX dimer interactions. The energies of 500 high-density structures resulting from molecular packing were minimized and the 14 lowest-energy structures were subjected to isothermal-isostress molecular dynamics (NsT-MD) simulations. For both crystal structure prediction methods and molecular dynamics simulations, the lowest-energy polymorph corresponded to the experimental structure; furthermore, the lattice energy of this polymorph was lower than that of the other polymorphs by at least 1.1 kcal mol(-1). Crystal parameters and densities of the low-energy crystal produced by the NsT-MD simulations matched those of the experimental crystal to within 1% of density and cell edge lengths and 0.01 degrees of the cell angle. The arrangement of the molecules within the time-averaged unit cell were in equally outstanding agreement with experiment, with the largest deviation of the location of the molecular mass centers being less than 0.07 angstrom and the largest deviation in molecular orientation being less than 2.8 degrees. NsT-MD simulations were also used to calculate crystallographic parameters as functions of temperature and pressure and the results were in a reasonable agreement with experiment.
C1 [Podeszwa, Rafal] Silesian Univ, Inst Chem, PL-40006 Katowice, Poland.
[Podeszwa, Rafal; Szalewicz, Krzysztof] Univ Delaware, Dept Phys & Astron, Newark, DE 19716 USA.
[Rice, Betsy M.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Podeszwa, R (reprint author), Silesian Univ, Inst Chem, Szkolna 9, PL-40006 Katowice, Poland.
FU ARO DEPSCOR; NSF [CHE-0555979]; Polish Science Foundation; Office of
Naval Research
FX This research was supported by an ARO DEPSCOR grant, by NSF grant
CHE-0555979, by the Polish Science Foundation grant Homing and the
Office of Naval Research. Most of the calculations were performed using
computer resources allocated by a DoD HPCMP Challenge Project.
NR 31
TC 34
Z9 34
U1 1
U2 24
PU ROYAL SOC CHEMISTRY
PI CAMBRIDGE
PA THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS,
ENGLAND
SN 1463-9076
J9 PHYS CHEM CHEM PHYS
JI Phys. Chem. Chem. Phys.
PY 2009
VL 11
IS 26
BP 5512
EP 5518
DI 10.1039/b902015b
PG 7
WC Chemistry, Physical; Physics, Atomic, Molecular & Chemical
SC Chemistry; Physics
GA 461VJ
UT WOS:000267300000035
PM 19551222
ER
PT J
AU Gerber, JP
Marcus, RL
Dibble, LE
Greis, PE
Burks, RT
LaStayo, PC
AF Gerber, J. Parry
Marcus, Robin L.
Dibble, Leland E.
Greis, Patrick E.
Burks, Robert T.
LaStayo, Paul C.
TI Effects of Early Progressive Eccentric Exercise on Muscle Size and
Function After Anterior Cruciate Ligament Reconstruction: A 1-Year
Follow-up Study of a Randomized Clinical Trial
SO PHYSICAL THERAPY
LA English
DT Article
ID PATELLAR TENDON; NEGATIVE WORK; STRENGTH; KNEE; REHABILITATION;
AUTOGRAFTS; MORPHOLOGY; ERGOMETRY; SURGERY; HUMANS
AB Background and Purpose. The authors previously reported that focused eccentric resistance training during the first 15 weeks following anterior cruciate ligament reconstruction (ACL-R) induced greater short-term increases in Muscle Volume, strength, and measures of function relative to standard rehabilitation. The purpose of this study was to evaluate the effects of early progressive eccentric exercise on muscle volume,and function at 1 year after ACL-R.
Participants and Methods. Forty patients who had undergone an ACL-R were randomly assigned to 1 of 2 groups: a group that received early progressive eccentric exercise (n=20) and a group that received standard rehabilitation (n=20). Seventeen participants in the eccentric exercise group and 15 participants in the standard rehabilitation group completed a 1-year follow-up. Magnetic resonance images of the thighs were acquired 1 year after ACL-R and compared with images acquired 3 weeks after surgery. Likewise, routine knee examinations, self-report assessments, and strength and functional testing were completed 1 year after surgery and compared with previous evaluations. A 2-factor analysis of variance for repeated measures (group X time) was used to analyze the data.
Results. Compared with the standard rehabilitation group, improvements in quadriceps femoris and gluteus maximus muscle volume in the involved lower extremity from 3 weeks to 1 year following ACL-R were significantly greater in the eccentric exercise group. Improvements in quadriceps femoris and gluteus maximus muscle volume were 23.3% (SD=14.1%) and 20.6% (SD=12.9%), respectively, in the eccentric exercise group and 13.4% (SD=10.3%) and 11.6% (SD=10.4%), respectively, in the standard rehabilitation group. Improvements in quadriceps femoris muscle strength and hopping distance also were significantly greater in the eccentric exercise group 1 year postsurgery.
Discussion and Conclusions. A 12-week focused eccentric resistance training program, implemented 3 -weeks after ACL-R, resulted in greater increases in quadriceps femoris and gluteus maximus muscle Volume and function compared with standard rehabilitation at 1 year following ACL-R.
C1 [Gerber, J. Parry] US Mil Baylor Univ, US Mil Acad, Postgrad Sports Med Residency Program, US Mil Acad,Keller Army Community Hosp, West Point, NY 10996 USA.
[LaStayo, Paul C.] Univ Utah, Dept Phys Therapy, Dept Exercise & Sport Sci, Salt Lake City, UT USA.
[Greis, Patrick E.; Burks, Robert T.; LaStayo, Paul C.] Univ Utah, Dept Orthoped, Salt Lake City, UT USA.
RP Gerber, JP (reprint author), US Mil Baylor Univ, US Mil Acad, Postgrad Sports Med Residency Program, US Mil Acad,Keller Army Community Hosp, West Point, NY 10996 USA.
EM john.Gerber@us.army.mil
FU American Physical Therapy Association
FX This study was funded, in part, by the American Physical Therapy
Association Orthopedic Section Clinical Research Grant to Dr Gerber and
Dr LaStayo.
NR 33
TC 49
Z9 52
U1 0
U2 5
PU AMER PHYSICAL THERAPY ASSOC
PI ALEXANDRIA
PA 1111 N FAIRFAX ST, ALEXANDRIA, VA 22314 USA
SN 0031-9023
J9 PHYS THER
JI Phys. Ther.
PD JAN
PY 2009
VL 89
IS 1
BP 51
EP 59
DI 10.2522/ptj.20070189
PG 9
WC Orthopedics; Rehabilitation
SC Orthopedics; Rehabilitation
GA 389FJ
UT WOS:000262076300005
PM 18988664
ER
PT J
AU Dreyfuss, P
Cohen, S
Chen, AS
Bohart, Z
Bogduk, N
AF Dreyfuss, Paul
Cohen, Steven
Chen, Allen Sinclair
Bohart, Zach
Bogduk, Nikolai
TI Is Immediate Pain Relief After a Spinal Injection Procedure Enhanced by
Intravenous Sedation?
SO PM&R
LA English
DT Article
AB Objective: To determine the effect of intravenous sedation on postprocedural pain relief for patients undergoing a spinal injection procedure in which there is no expectation of immediate relief.
Design: A prospective audit to compare Visual Analog Scale (VAS) responses before and after interlaminar epidural corticosteroid injections without epidural anesthetic in those who did and did not receive intravenous sedation.
Setting: This audit was undertaken in 2 interventional spine practices.
Patients: A total of 102 patients were allotted to receive or not receive intravenous sedation depending on preference.
Interventions: Inter laminar epidural injections of corticosteroid without epidural anesthetic.
Main Outcome Measurements: Outcomes were measured by mean (VAS) scores after the procedure and mean VAS differences before and after the procedure.
Results: There were no significant differences between mean VAS scores or mean differences in VAS scores between those who did or did not receive intravenous sedation. A relatively high percentage of patients in both groups obtained greater than 50% immediate pain relief.
Conclusion: Intravenous mild or moderate conscious sedation did not have an effect on postprocedural VAS pain scores in those receiving a therapeutic spinal injection procedure. Immediate pain relief was most likely the result of nonspecific effects.
C1 [Dreyfuss, Paul] Univ Washington, Dept Rehabil Med, Bellevue, WA 98004 USA.
[Cohen, Steven] Johns Hopkins Sch Med, Dept Anesthesia & Crit Care Med, Baltimore, MD USA.
[Cohen, Steven] Walter Reed Army Med Ctr, Washington, DC 20307 USA.
[Chen, Allen Sinclair; Bohart, Zach] Univ Washington, Dept Rehabil Med, Seattle, WA 98195 USA.
[Bogduk, Nikolai] Univ Newcastle, Royal Newcastle Hosp, Dept Clin Res, Callaghan, NSW 2308, Australia.
RP Dreyfuss, P (reprint author), Univ Washington, Dept Rehabil Med, 12301 NE 10th Pl,Suite 101, Bellevue, WA 98004 USA.
EM pauldreyfuss@gmail.com
NR 12
TC 2
Z9 2
U1 0
U2 0
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1934-1482
J9 PM&R
JI PM&R
PD JAN
PY 2009
VL 1
IS 1
BP 60
EP 63
DI 10.1016/j.pmrj.2008.10.006
PG 4
WC Rehabilitation; Sport Sciences
SC Rehabilitation; Sport Sciences
GA V24LD
UT WOS:000208411000010
PM 19627874
ER
PT S
AU Felton, M
Gurton, KP
Roth, LE
Pezzaniti, JL
Chenault, DB
AF Felton, M.
Gurton, K. P.
Roth, L. E.
Pezzaniti, J. L.
Chenault, D. B.
BE Shaw, JA
Tyo, JS
TI Measured comparison of the inversion periods for polarimetric and
conventional thermal long-wave IR (LWIR) imagery
SO POLARIZATION SCIENCE AND REMOTE SENSING IV
SE Proceedings of SPIE
LA English
DT Proceedings Paper
CT Conference on Polarization Science and Remote Sensing IV
CY AUG 03-04, 2009
CL San Diego, CA
SP SPIE
DE Polarimetric imaging; thermal imaging; microbolometer; target contrast;
inversion periods
AB We report the results of a multi-day diurnal study in which radiometrically calibrated polarimetric and conventional thermal imagery is recorded in the LWIR to identify/compare the respective time periods in which minimum target contrast is achieved, e. g., thermal inversion periods are typically experienced during dusk and dawn. Imagery is recorded with a polarimetric IR sensor employing a 324x256 microbolometer array using a spinning achromatic retarder to perform the polarimetric filtering. The images used in this study include the S-0, normalized S-1, and normalized S-2 Stokes images and the degree of linear polarization (DOLP) images of a scene containing military vehicles and the natural background. In addition, relevant meteorological parameters measured during the test period include air temperature, ambient loading in the LWIR, relative humidity, and cloud cover, height and density. The data shows that the chief factors affecting polarimetric contrast are the amount of thermal emission from the objects in the scene and the abundance of LWIR sources in the optical background. In addition, we found that contrast between targets and background within polarimetric images often remains relatively high during periods of low thermal contrast.
C1 [Felton, M.; Gurton, K. P.] USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
[Roth, L. E.] USA, Armament Res & Dev Engn Ctr, Picatinny Arsenal, NJ 07806 USA.
[Pezzaniti, J. L.; Chenault, D. B.] Polaris Sensor Technol Inc, Huntsville, AL 35801 USA.
RP Felton, M (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM mfelton@arl.army.mil
NR 6
TC 3
Z9 3
U1 0
U2 0
PU SPIE-INT SOC OPTICAL ENGINEERING
PI BELLINGHAM
PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
SN 0277-786X
BN 978-0-8194-7751-4
J9 PROC SPIE
PY 2009
VL 7461
AR UNSP 74610A
DI 10.1117/12.825355
PG 13
WC Remote Sensing; Optics
SC Remote Sensing; Optics
GA BCJ99
UT WOS:000310357000009
ER
PT S
AU Gurton, KP
Felton, M
AF Gurton, Kristan P.
Felton, Melvin
BE Shaw, JA
Tyo, JS
TI Detection of disturbed earth using passive LWIR polarimetric imaging
SO POLARIZATION SCIENCE AND REMOTE SENSING IV
SE Proceedings of SPIE
LA English
DT Proceedings Paper
CT Conference on Polarization Science and Remote Sensing IV
CY AUG 03-04, 2009
CL San Diego, CA
SP SPIE
ID MINE DETECTION; ROC ANALYSIS; SENSORS
AB We report test results of a study to assess the applicability for using passive polarimetric imaging in the long-wave infrared (LWIR) to detect regions of recently altered road-type surfaces, e.g., soil, gravel, asphalt, etc. The field test was conducted at the U.S. Army Research Laboratory, Adelphi, MD, on a test surface best described as a well traveled dirt road consisting of a gravel clay-soil mixture that was well compacted. During this initial proof-of-concept test, a LWIR polarimetric camera system was positioned at a slant-path of 10 degrees with respect to the line-of-site (LOS) and the natural lay of the surface, approximately 15 meters from the target test-bed. Stokes images, S0, S1, and S2, were recorded using the LWIR polarimeter that utilizes a spinning achromatic retarder design mated to Mercury Cadmium Telluride (MCT) focal plane array (FPA). Various surrogate targets were buried near the surface and great care was taken to camouflage the area to eliminate any "visible" signs of disturbance. Thermal gradients resulting from the unearthing of cool soil were allowed to dissipate. Two metrics were used to evaluate performance, i.e., conventional receiver operating characteristic (ROC) curve analysis and an effective contrast ratio between the target and background. Results showed particularly good detectability in the S2 imagery, with less in S1, and no detectability in S0, i.e., the conventional LWIR thermal image.
C1 [Gurton, Kristan P.; Felton, Melvin] USA, Res Lab, Adelphi, MD 20783 USA.
RP Gurton, KP (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
NR 25
TC 1
Z9 1
U1 0
U2 2
PU SPIE-INT SOC OPTICAL ENGINEERING
PI BELLINGHAM
PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
SN 0277-786X
BN 978-0-8194-7751-4
J9 PROC SPIE
PY 2009
VL 7461
AR 746115
DI 10.1117/12.837779
PG 15
WC Remote Sensing; Optics
SC Remote Sensing; Optics
GA BCJ99
UT WOS:000310357000033
ER
PT S
AU Bruno, FF
Belton, LE
Sleeves, DM
AF Bruno, Ferdinando F.
Belton, Lauren E.
Sleeves, Diane M.
BE Bauer, S
Cheng, Z
Wrobleski, DA
Zhang, Q
TI Novel Enzymatic Polymerization of Diazo Compounds: A New Group of Dyes
SO POLYMER-BASED SMART MATERIALS - PROCESSES, PROPERTIES AND APPLICATION
SE Materials Research Society Symposium Proceedings
LA English
DT Proceedings Paper
CT Symposium on Polymer-Based Materials held at the 2008 MRS Fall Meeting
CY DEC 02-05, 2008
CL Boston, MA
SP Mat Res Soc
ID PEROXIDASE; POLYMERS
AB The homopolymerization of Sudan Orange G, Disperse Orange 3, Calcon, Mordant Yellow 12, Disperse Orange 13, and Bismarck Brown Y, was mediated by the enzyme horseradish peroxidase. Fourier transform infrared (FTIR) spectroscopy and matrix assisted time-of-flight mass spectrometry (MALDI-TOF) was utilized to confirm the polymeric structures. The enzymatic reaction produced novel electroluminescent polymers that exhibit a red or a blue shift, and enhanced non-linear optical behavior when compared to the corresponding monomers. The results of detailed optical analysis of the polymeric materials will be presented.
C1 [Bruno, Ferdinando F.; Belton, Lauren E.; Sleeves, Diane M.] US Army Natick Soldier Res, Ctr Dev & Engn, Natick, MA 01760 USA.
RP Bruno, FF (reprint author), US Army Natick Soldier Res, Ctr Dev & Engn, Natick, MA 01760 USA.
NR 9
TC 0
Z9 0
U1 1
U2 2
PU MATERIALS RESEARCH SOCIETY
PI WARRENDALE
PA 506 KEYSTONE DRIVE, WARRENDALE, PA 15088-7563 USA
SN 0272-9172
BN 978-1-60511-106-3
J9 MATER RES SOC SYMP P
PY 2009
VL 1134
BP 91
EP 96
PG 6
WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary;
Polymer Science
SC Science & Technology - Other Topics; Materials Science; Polymer Science
GA BMR07
UT WOS:000273375700014
ER
PT B
AU Albert, DG
Decato, SN
Perron, FE
AF Albert, D. G.
Decato, S. N.
Perron, F. E., Jr.
BE Ling, HI
Smyth, A
Betti, R
TI Experimental Measurements of the Biot Slow Wave in Natural Snow Covers
SO PORO-MECHANICS IV
LA English
DT Proceedings Paper
CT 4th Biot Conference on Poromechanics
CY JUN 08-10, 2009
CL Columbia Univ, New York, NY
SP Columbia Univ, Sch Engn & Appl Sci, Univ Oklahoma, Poromechan Inst, ASCE Engn Mech Inst, ADAMA Engn, ERG Construct Trade & Ins Co Inc
HO Columbia Univ
ID OUTDOOR SOUND-PROPAGATION; ABSORPTION; FREQUENCY
AB The quiet conditions produced by a snow cover on the ground have been noticed by many observers, but few have realized that the sound attenuation is caused by Biot slow waves induced into this highly porous material. We present a measurement illustrating this attenuation for a surface microphone in the presence of a thin seasonal snow cover, then discuss a separate measurement on a thick snow cover designed to confirm the presence of the Biot slow wave by determining its velocity. The latter measurements used vertical sledge hammer blows and blank pistol shots to generate horizontally propagating waves 69 meters from the acoustic (microphone) and seismic (geophone) sensor location. For both sources, seismic P1 compressional, shear, and Rayleigh waves are visible on the measured time series, followed by the airborne acoustic arrival. The acoustic arrival generates additional P1 ice frame waves and Biot P2 slow waves that propagate downward from the snow surface at measured velocities of 460 and 95 m/s, respectively. By comparing the measured waveforms with theoretical calculations for a rigid porous medium, the Biot P2 slow wave can account for the distortion and attenuation visible in the atmospheric acoustic wave. The agreement can be used to determine snow permeability, a parameter otherwise hard to measure on natural snow, and for shallow snow covers this procedure also provides an accurate estimate of snow cover depth. Separate small scale laboratory measurements show that the P2 wave in snow is dispersed (the velocity increases with increasing frequency) in agreement with the trend predicted by Biot's theory, but with some parameter adjustments needed to obtain the best agreement.
C1 [Albert, D. G.; Decato, S. N.; Perron, F. E., Jr.] ERDC CRREL, Hanover, NH 03755 USA.
RP Albert, DG (reprint author), ERDC CRREL, 72 Lyme Rd, Hanover, NH 03755 USA.
NR 19
TC 1
Z9 1
U1 1
U2 2
PU DESTECH PUBLICATIONS, INC
PI LANCASTER
PA 439 DUKE STREET, LANCASTER, PA 17602-4967 USA
BN 978-1-60595-006-8
PY 2009
BP 724
EP 729
PG 6
WC Materials Science, Multidisciplinary; Mechanics; Physics, Fluids &
Plasmas
SC Materials Science; Mechanics; Physics
GA BLG88
UT WOS:000270143600109
ER
PT S
AU Cole, DM
Hopkins, MA
AF Cole, David M.
Hopkins, Mark A.
BE Nakagawa, M
Luding, S
TI Contact Mechanics of Naturally Occurring Grains: Experiments and
Discrete Element Modeling
SO POWDERS AND GRAINS 2009
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 6th International Conference on the Micromechanics of Granular Media
CY JUL 13-17, 2009
CL Golden, CO
SP Assoc Study Micromech Granular Media, Univ Twente, Colorado Sch Mines
DE Contact mechanics; experiments; geologic materials; discrete element
modeling
AB Application of the discrete element method to engineering problems involving naturally occurring granular materials requires knowledge of the contact mechanics of the particles and a realistic treatment of particle shapes. This paper presents results from on-going work that addresses these two fundamental issues of granular media mechanics. Grain-scale laboratory experiments are being conducted to provide the needed contact relationships. A concurrent discrete element modeling effort is under way to implement the experimentally determined contact relationships and employ realistic particle shapes.
The experiments determine the stiffness and frictional behavior of normal and sliding contacts of observed for spherical specimens of gneiss. Stiffness in the normal mode is seen to range from 0.1 to 15 MN m(-1) depending on force level. Shear stiffness is on the order of the normal stiffness, but only for relatively low shear force levels (or shear deformations). Frictional energy losses are observed to varying degrees under virtually all experimental conditions. The discrete element modeling effort simulates the triaxial response of the spherical grains enclosed in a membrane and implements the experimentally determined contact relationships for normal and sliding contact behavior. Inclusion of the full frictional behavior prior to macroscopic sliding is under development. Some aspects of the simulations of the triaxial deformation of spherical grains of gneiss are presented and compared with the grain-scale experimental data. The simulations are seen to capture the key features of the experimental observations.
C1 [Cole, David M.; Hopkins, Mark A.] USA, Cold Reg Res & Engn Lab, Engineer Res & Dev Ctr, Hanover, NH 03755 USA.
RP Cole, DM (reprint author), USA, Cold Reg Res & Engn Lab, Engineer Res & Dev Ctr, 72 Lyme Rd, Hanover, NH 03755 USA.
NR 10
TC 4
Z9 4
U1 0
U2 3
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0682-7
J9 AIP CONF PROC
PY 2009
VL 1145
BP 351
EP 354
PG 4
WC Materials Science, Multidisciplinary; Mechanics
SC Materials Science; Mechanics
GA BLN80
UT WOS:000270602900077
ER
PT J
AU Holcomb, J
McManus, J
Kerr, ST
Pusateri, A
AF Holcomb, John B.
McManus, John G.
Kerr, S. T.
Pusateri, Anthony E.
TI Needle versus Tube Thoracostomy in a Swine Model of Traumatic Tension
Hemopneumothorax
SO Prehospital Emergency Care
LA English
DT Article
DE tension pneumothorax; tube thoracostomy; needle thoracostomyn
ID INSUFFICIENT CANNULA LENGTH; CHEST-WALL THICKNESS; POTENTIAL FAILURE;
PNEUMOTHORAX; THORACENTESIS
AB Objective. Traumatic tension hemopneumothorax is fatal if not treated rapidly. However, whether prehospital decompression is better achieved by chest tube or needle thoracostomy is unknown. We conducted this study to compare the immediate results and prolonged effectiveness of two methods of treatment for traumatic tension hemopneumothorax in a swine model. Methods. Ten percent of calculated total blood volume was instilled into the hemithorax of spontaneously ventilating swine (n = 5 per group, 40 3 kg). A Veres needle and insufflator were used to induce tension hemopneumothorax. Animals were randomized to one of four groups: 1) needle thoracostomy with 14-gauge intravenous catheter; 2) needle thoracostomy with Cook catheter; 3) 32-F chest tube thoracostomy; or 4) no intervention (control). Serial chest x-rays were obtained to document mediastinal shift before and after treatment. Arterial blood gas values and physiologic data were recorded. Postoperatively, thoracoscopy was performed to detect possible pulmonary injury from the procedure and/or catheter kinking or clotting. Results. Positive intrapleural pressure was rapidly relieved in all treated animals. Four-hour survival was 100% in the 14-gauge needle and chest tube thoracostomy groups, 60% in the Cook catheter group, and 0% in the control animals (p 0.05). There were no significant differences in survival or physiologic measurements among the treated animals (p 0.05). Conclusions. In this animal model, needle thoracostomy using a 14-gauge or Cook catheter was as successful as chest tube thoracostomy for relieving tension hemopneumothorax.
C1 [Holcomb, John B.; McManus, John G.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA.
[Kerr, S. T.] USN, Med Ctr, San Diego, CA USA.
[Pusateri, Anthony E.] Novo Nordisk AS, Princeton, NJ USA.
RP Holcomb, J (reprint author), USA, Inst Surg Res, 3400 Rawley E Chambers Ave, Ft Sam Houston, TX 78234 USA.
EM john.holcomb@amedd.army.mil
FU United States Marine Corps
FX Supported by a Combat Casualty Care grant from the United States Marine
Corps. Cook Catheters were provided by the Cook Group Company.
NR 24
TC 16
Z9 16
U1 0
U2 0
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
SN 1090-3127
J9 PREHOSP EMERG CARE
JI Prehosp. Emerg. Care
PY 2009
VL 13
IS 1
BP 18
EP 27
AR PII 907832556
DI 10.1080/10903120802290760
PG 10
WC Emergency Medicine; Public, Environmental & Occupational Health
SC Emergency Medicine; Public, Environmental & Occupational Health
GA 394UQ
UT WOS:000262476500004
PM 19145520
ER
PT J
AU McNeil, C
McManus, J
Mehta, S
AF McNeil, Christopher R.
McManus, John
Mehta, Sumeru
TI The Accuracy of Portable Ultrasonography to Diagnose Fractures in an
Austere Environment
SO Prehospital Emergency Care
LA English
DT Article
DE ultrasound; fracture; postreduction; orthopedic; realignment; austere
environment; combat medicine
ID SONOGRAPHIC DETECTION; ULTRASOUND DIAGNOSIS; TRAUMA; BONE
AB Background. Previous literature has shown the ability of ultrasonography technology to accurately assess orthopedic pathology. Over the past two decades, the use of ultrasound in the prehospital setting has become an important tool for triage, diagnosis, and treatment, especially in austere and remote environments that lack appropriate radiography capability and logistical support. The purpose of our study was to assess the accuracy of ultrasound in the austere, combat environment for diagnosis of orthopedic fracture. Methods. We conducted a longitudinal, prospective, observational study on patients presenting with suspected closed fractures using a digital handheld ultrasound device. All patients presenting with suspected fracture underwent an ultrasound examination by a board-certified emergency medicine physician credentialed in emergency ultrasonography. Patients were then categorized into ultrasound-positive and ultrasound-negative groups. Results. A total of 44 subjects underwent ultrasound examination for suspected fractures. There were initially 12 (27%) positive and 32 (73%) negative scans. Of the initial 12 positive scans, ten had a true fracture verified by plain radiography. Ultrasonography yielded an overall sensitivity of 100% and a specificity of 94%. Only four patients with an initial negative ultrasound scan continued to have clinical symptoms for more than three days and were found to have no evidence of fracture by radiograph. Conclusions. Our data show that use of ultrasound by an experienced clinician in the austere environment can be performed accurately and can possibly prevent unnecessary evacuations for suspected fractures requiring radiographic verification. The purpose of our study was to assess the accuracy of ultrasound examination in the austere, combat environment for diagnosis of orthopedic fracture.
C1 [McNeil, Christopher R.; McManus, John; Mehta, Sumeru] Brooke Army Med Ctr, Dept Emergency Med, San Antonio, TX USA.
RP McNeil, C (reprint author), BAMC, Dept Emergency Med, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA.
EM john.mcmanus@amedd.army.mil
NR 14
TC 20
Z9 21
U1 0
U2 2
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
SN 1090-3127
J9 PREHOSP EMERG CARE
JI Prehosp. Emerg. Care
PY 2009
VL 13
IS 1
BP 50
EP 52
AR PII 907832902
DI 10.1080/10903120802474513
PG 3
WC Emergency Medicine; Public, Environmental & Occupational Health
SC Emergency Medicine; Public, Environmental & Occupational Health
GA 394UQ
UT WOS:000262476500008
PM 19145524
ER
PT J
AU Black, IH
McManus, J
AF Black, Ian H.
McManus, John
TI Pain Management in Current Combat Operations
SO PREHOSPITAL EMERGENCY CARE
LA English
DT Article
DE pain; pain management; battlefield; combat
ID TRANSMUCOSAL FENTANYL CITRATE; CYCLOOXYGENASE-2 INHIBITORS;
POSTOPERATIVE PAIN; CASUALTY CARE; NERVE BLOCK; KETAMINE; GABAPENTIN;
ANALGESIA; ENVIRONMENT; VOLUNTEERS
AB Pain management in the U.S. Military, particularly in combat, shares many of the same principles found in civilian heath care organizations and institutions. Pain is one of the most common reasons for which soldiers seek medical attention in the combat environment, which mirrors the civilian experience. However, the combat environment exacerbates the typical challenges found in treating acute pain and has the additional obstacles of a lack of supplies and equipment, delayed or prolonged evacuation times and distances, devastating injuries, provider inexperience, and dangerous tactical situations. These factors contribute to the difficulty in controlling a soldier's pain in combat. Furthermore, civilian health care providers have also learned the importance of practicing pain management principles in austere and tactical environments because of recent natural and man-made domestic disasters. Pain management research, education, and treatment strategies have been created to try to achieve adequate battlefield analgesia, and these lessons learned may aid civilian health care providers if the circumstances arise. This article presents a brief history and current overview of pain management for combat casualties on today's battlefield. Recent natural disasters and increased threats for terrorist acts have proven the need for civilian health care providers to be properly trained in pain management principles in an austere or tactical environment.
C1 [Black, Ian H.; McManus, John] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA.
RP McManus, J (reprint author), Brooke Army Med Ctr, Dept Emergency Med, Roger Brooke Dr, Ft Sam Houston, TX 78234 USA.
EM john.mcmanus@amedd.army.mil
NR 40
TC 17
Z9 18
U1 0
U2 10
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
SN 1090-3127
J9 PREHOSP EMERG CARE
JI Prehosp. Emerg. Care
PY 2009
VL 13
IS 2
BP 223
EP 227
AR PII 909567478
DI 10.1080/10903120802290778
PG 5
WC Emergency Medicine; Public, Environmental & Occupational Health
SC Emergency Medicine; Public, Environmental & Occupational Health
GA 419MT
UT WOS:000264224400012
PM 19291561
ER
PT J
AU Chen, LY
Reisner, AT
Gribok, A
Reifman, J
AF Chen, Liangyou
Reisner, Andrew T.
Gribok, Andrei
Reifman, Jaques
TI Exploration of Prehospital Vital Sign Trends for the Prediction of
Trauma Outcomes
SO PREHOSPITAL EMERGENCY CARE
LA English
DT Article
DE vital signs; trauma; hemorrhage; trends; variability
ID INTENSIVE-CARE-UNIT; BLOOD-PRESSURE; LIFESAVING INTERVENTIONS;
HYPOTENSION; MORTALITY; TRIAGE; SCORE; HYPOVOLEMIA; HELICOPTERS;
TRANSPORT
AB Objectives. We explored whether there are diagnostically useful temporal trends in prehospital vital signs of trauma patients. Methods. Vital signs were monitored during transport to a level I trauma center and electronically archived. Retrospectively, we identified reliable vital signs recorded from the 0- to 7-minute interval and from the 14- to 21-minute interval during transport, and, for each subject, we computed the temporal differences between the two intervals' vital signs, the intrasubject 95% data ranges, the values during the initial 2 minutes, and the 21-minute overall means. We tested for differences between subjects with major hemorrhage versus control subjects, and computed receiver-operating characteristic (ROC) curves. We conducted sensitivity analyses, exploring alternative clinical outcomes, temporal windows, and methods of identifying reliable data. Results. Comparing major hemorrhage cases versus controls, there were no discriminatory differences in temporal vital sign trends. Hemorrhage cases had significantly wider intrasubject data ranges for systolic blood pressure (SBP), respiratory rate (RR), and shock index (SI) versus controls. All results were consistent in several sensitivity analyses. Conclusions. Our findings add to a growing body of evidence that prehospital vital sign trends over 21 minutes or less are unlikely to be diagnostically useful because of substantial nondirectional fluctuations in vital signs that would obscure any subtle, progressive temporal trends. SBP, RR, and SI values were significantly different for high-acuity patients, and had more variability. Taken together, these findings suggest that higher-acuity patients experience episodes of instability rather than gradual, steady decline. Measures that account for data variability, such as taking the average of multiple measurements, may improve the diagnostic utility of prehospital vital signs.
C1 [Chen, Liangyou; Reisner, Andrew T.; Gribok, Andrei; Reifman, Jaques] USA, Med Res & Mat Command, TATRC, Ft Detrick, MD USA.
[Reisner, Andrew T.] Massachusetts Gen Hosp, Dept Emergency Med, Boston, MA 02114 USA.
RP Reifman, J (reprint author), USA, Med Res & Mat Command, TATRC, ATTN MCMR TT Bldg 363 Miller Dr, Ft Detrick, MD USA.
EM reifman@us.army.mil
FU Combat Casualty Care Research Area Directorate of the U. S. Army Medical
Research and Materiel Command, Fort Detrick, Maryland
FX Supported by the Combat Casualty Care Research Area Directorate of the
U. S. Army Medical Research and Materiel Command, Fort Detrick,
Maryland. The authors have no conflicts of interest to disclose.
NR 32
TC 27
Z9 28
U1 0
U2 4
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
SN 1090-3127
J9 PREHOSP EMERG CARE
JI Prehosp. Emerg. Care
PY 2009
VL 13
IS 3
BP 286
EP 294
AR PII 912029366
DI 10.1080/10903120902935298
PG 9
WC Emergency Medicine; Public, Environmental & Occupational Health
SC Emergency Medicine; Public, Environmental & Occupational Health
GA 454AQ
UT WOS:000266654400003
PM 19499463
ER
PT J
AU Gerhardt, RT
Matthews, JM
Sullivan, SG
AF Gerhardt, Robert T.
Matthews, Joseph M.
Sullivan, Scott G.
TI The Effect of Systemic Antibiotic Prophylaxis and Wound Irrigation on
Penetrating Combat Wounds in a Return-to-Duty Population
SO PREHOSPITAL EMERGENCY CARE
LA English
DT Article
CT Research Forum of the American-College-of-Emergency-Physicians
CY OCT 24-28, 2008
CL Chicago, IL
SP Amer Coll Emergency Phys
DE antibiotic prophylaxis; penetrating trauma; military medicine; war;
wound infection; wound irrigation
ID PREVENTION; MANAGEMENT; INFECTION; INJURIES
AB Background. Systemic antibiotic prophylaxis (SAP) for combat wounds is controversial. Current military practice favors its use, despite scant supporting evidence. Objective. To analyze outcomes of combat casualties returned to duty after initial wound care for penetrating trauma, comparing infection rates based on whether SAP was administered and whether wounds were irrigated. Setting: Forward operating base in Central Iraq, with units engaged in urban combat. Methods. This was a retrospective cohort study using field medical records. Wound mechanism, location, antibiotic use, and clinical course were abstracted. Subjects were excluded if injuries were isolated burns or eye trauma or if follow-up was not documented. Statistical analysis: Contingency table analysis, Fisher's exact test, and odds ratios were used. Results. Fifty-eight eligible cases were identified; five were excluded for incomplete follow-up (four) or confounding injuries (one). Of the remaining 53 cases, 43 included receipt of SAP (81%). Wound mechanisms and anatomic locations were comparable between groups. Infections developed within 48 hours in 7% of the SAP cases versus 40% without SAP (no SAP); odds ratio 0.11 (95% confidence interval [CI] 0.02 to 0.57); number needed to treat (NNT) 3 (95% CI 2 to 14). Forty-four subjects received wound irrigation (83%). Infections developed within 48 hours in two (4.5%) irrigated cases versus five (55%) without irrigation (no irrigation); odds ratio 0.04 (95% CI 0.006 to 0.24); NNT 2 (95% CI 1.4 to 4.7). Further 4 x 2 contingency table analysis yielded wound infection rates as follows: no SAP/irrigation, 17%; SAP/no irrigation, 40%; SAP/irrigation, 2.6%; no SAP/no irrigation, 75% (Fisher's exact p 0.0005). Conclusions. We detected independent and combined associations among SAP, irrigation, and significantly decreased wound infection rates. Effects of SAP and irrigation may be synergistic. Copious irrigation with potable water or sterile isotonic solution should be performed at the earliest practical juncture after a wound occurs. SAP should be administered if irrigation cannot be performed, and may be warranted in addition to irrigation for complex or contaminated wounds or if expeditious return to duty is required. Larger epidemiologic studies are needed to validate our findings.
C1 [Gerhardt, Robert T.; Matthews, Joseph M.] Brooke Army Med Ctr, Dept Emergency Med, San Antonio Uniformed Serv Hlth Educ Consortium, Ft Sam Houston, TX 78234 USA.
[Gerhardt, Robert T.] Uniformed Serv Univ Hlth Sci, Dept Mil & Emergency Med, Bethesda, MD 20814 USA.
[Gerhardt, Robert T.; Sullivan, Scott G.] 12th US Cavalry Regiment, Battal 1, Cavalry Div 1, Ft Hood, TX USA.
[Gerhardt, Robert T.] US Army Inst Surg Res, Prehosp Res Branch, Ft Sam Houston, TX USA.
RP Gerhardt, RT (reprint author), Brooke Army Med Ctr, Dept Emergency Med, San Antonio Uniformed Serv Hlth Educ Consortium, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA.
EM robert.gerhardt@us.army.mil
NR 9
TC 9
Z9 9
U1 0
U2 1
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
SN 1090-3127
J9 PREHOSP EMERG CARE
JI Prehosp. Emerg. Care
PY 2009
VL 13
IS 4
BP 500
EP 504
AR PII 914289530
DI 10.1080/10903120903144841
PG 5
WC Emergency Medicine; Public, Environmental & Occupational Health
SC Emergency Medicine; Public, Environmental & Occupational Health
GA 491TM
UT WOS:000269602500013
PM 19731163
ER
PT S
AU Hainer, MI
Sketch, MH
AF Hainer, Mark I.
Sketch, Michael H.
BE Tcheng, JE
TI Operator and Site Requirements for Primary Coronary Intervention
SO PRIMARY ANGIOPLASTY IN ACUTE MYOCARDIAL INFARCTION, SECOND EDITION
SE Contemporary Cardiology
LA English
DT Article; Book Chapter
ID ACUTE-MYOCARDIAL-INFARCTION; NEW-YORK-STATE; PRACTICE GUIDELINES
COMMITTEE; ASSOCIATION TASK-FORCE; PRIMARY ANGIOPLASTY; ON-SITE;
AMERICAN-COLLEGE; THROMBOLYTIC THERAPY; ACC/AHA GUIDELINES; NATIONAL
REGISTRY
C1 [Sketch, Michael H.] Duke Univ, Med Ctr, Div Cardiol, Durham, NC 27710 USA.
[Hainer, Mark I.] William Beaumont Army Med Ctr, Ft Bliss, TX USA.
RP Sketch, MH (reprint author), Duke Univ, Med Ctr, Div Cardiol, Durham, NC 27710 USA.
EM sketc002@mc.duke.edu
NR 44
TC 0
Z9 0
U1 0
U2 0
PU HUMANA PRESS INC
PI TOTOWA
PA 999 RIVERVIEW DR, STE 208, TOTOWA, NJ 07512-1165 USA
SN 1191-7601
BN 978-1-60327-497-5
J9 CONTEMP CARDIOL
JI Contemp. Cardiol.
PY 2009
BP 27
EP 46
DI 10.1007/978-1-60327-497-5_3
D2 10.1007/978-1-60327-497-5
PG 20
WC Cardiac & Cardiovascular Systems
SC Cardiovascular System & Cardiology
GA BNF85
UT WOS:000274463900003
ER
PT B
AU Maymi, FJ
Rodriguez-Martinez, M
AF Maymi, Fernando J.
Rodriguez-Martinez, Manuel
GP IEEE Computer Society
TI Obstacle Avoidance for Utility-Based Geocasting
SO PROCEEDINGS OF THE 2009 SIXTH INTERNATIONAL CONFERENCE ON INFORMATION
TECHNOLOGY: NEW GENERATIONS, VOLS 1-3
LA English
DT Proceedings Paper
CT 6th International Conference on Information Technology - New Generations
(ITNG 2009)
CY APR 27-29, 2009
CL Las Vegas, NV
SP IEEE Comp Soc
AB Geocasting is the delivery of messages to all recipients within a specific geospatial region. While good algorithms exist to provide geocasting services, they do not perform well in the presence of large obstacles. We define an obstacle as any region of the network through which a message may not be directly transmitted. Given this definition, we developed a simple mechanism that allows messages to skirt around obstacles and ultimately reach their destination. We claim that this approach can dramatically improve the delivery rates of messages in adverse topologies, and support our claim with experimental results including both our utility function based geocasting protocol as well as the well-known Location Based Multicast (LBM) and Voronoi Region multicasting approaches.
C1 [Maymi, Fernando J.] Univ Puerto Rico, US Army, Mayaguez, PR 00931 USA.
[Rodriguez-Martinez, Manuel] Univ Puerto Rico, Dept Elect & Comp Engn, Mayaguez, PR USA.
RP Maymi, FJ (reprint author), Univ Puerto Rico, US Army, Mayaguez, PR 00931 USA.
EM fernando.maymi@us.army.mil; manuel.rodriguez7@upr.edu
NR 8
TC 0
Z9 0
U1 0
U2 0
PU IEEE
PI NEW YORK
PA 345 E 47TH ST, NEW YORK, NY 10017 USA
BN 978-1-4244-3770-2
PY 2009
BP 338
EP +
DI 10.1109/ITNG.2009.326
PG 2
WC Computer Science, Artificial Intelligence; Computer Science, Information
Systems; Computer Science, Software Engineering; Computer Science,
Theory & Methods
SC Computer Science
GA BLQ66
UT WOS:000270815100059
ER
PT S
AU Ahner, D
AF Ahner, Darryl
GP IEEE
TI A NORMALIZED WEIGHTED ENTROPY MEASURE FOR SENSOR ALLOCATION WITHIN
SIMULATIONS
SO PROCEEDINGS OF THE 2009 WINTER SIMULATION CONFERENCE (WSC 2009 ), VOL
1-4
SE Winter Simulation Conference Proceedings
LA English
DT Proceedings Paper
CT Winter Simulation Conference 2009
CY DEC 13-16, 2009
CL Austin, TX
SP IEEE
ID QUALITY
AB Information superiority is considered a critical capability for future joint forces. Sensor allocation and information processing are critical to achieving this information superiority but the value of information is difficult to assess. We develop a weighted entropy measure for sensor allocation within simulations by using the Dynamic Model of Situated Cognition as a framework in which to view the processing and flow of information in a complex technological-cognitive system. The entropy measure developed is normalized across each requirement and weighted according to the Commander's priorities within the phase of that operation. We develop a methodology for implementation for this normalized weighted entropy measure to allocate sensors within a combat simulation.
C1 US Mil Acad, Dept Math Sci, West Point, NY 10996 USA.
RP Ahner, D (reprint author), US Mil Acad, Dept Math Sci, West Point, NY 10996 USA.
EM darryl.ahner@us.army.mil
NR 22
TC 0
Z9 0
U1 0
U2 0
PU IEEE
PI NEW YORK
PA 345 E 47TH ST, NEW YORK, NY 10017 USA
SN 0891-7736
BN 978-1-4244-5770-0
J9 WINT SIMUL C PROC
PY 2009
BP 1712
EP 1722
PG 11
WC Computer Science, Information Systems; Engineering, Electrical &
Electronic; Operations Research & Management Science
SC Computer Science; Engineering; Operations Research & Management Science
GA BUJ11
UT WOS:000289492501023
ER
PT B
AU Pelaez, JC
AF Pelaez, Juan C.
BE Tjoa, AM
Wagner, RR
TI Using Misuse Patterns for VoIP Steganalysis
SO PROCEEDINGS OF THE 20TH INTERNATIONAL WORKSHOP ON DATABASE AND EXPERT
SYSTEMS APPLICATION
LA English
DT Proceedings Paper
CT 20th International Conference on Database and Expert Systems
Applications
CY AUG 31-SEP 04, 2009
CL Linz, AUSTRIA
SP DEXA Assoc, Austrian Comp Soc, Res Inst Appl Knowledge Proc, Johannes Kepler Univ Linz
AB The growing interest in Voice over Internet Protocol (VoIP) communications increased the fear that criminal and terrorist groups are switching to this technology to coordinate their operations. VoIP services that cannot be monitored and lawfully intercepted may be used to perform illegal activity. Converged networks are vulnerable to steganographic attacks due to their high bandwidth usage. This feature provides a way to embed hidden messages in either the VoIP signaling or media streams making steganalysis harder to accomplish. This paper discusses a systematic approach to analyze steganography in VoIP using misuse patterns [PeI09]. Misuse patterns describe, from the point of view of the attacker, how a type of information misuse is performed, analyzes the ways of stopping the attack, and considers how to trace the attack once it has happened. The pattern also attempts to correlate events with specific parts of the system. We will use these semiformal models as a method to improve the detection of embedded hidden messages in IP telephony.
C1 USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Pelaez, JC (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
EM juan.c.pelaez@arl.army.mil
NR 9
TC 0
Z9 0
U1 0
U2 0
PU IEEE COMPUTER SOC
PI LOS ALAMITOS
PA 10662 LOS VAQUEROS CIRCLE, PO BOX 3014, LOS ALAMITOS, CA 90720-1264 USA
BN 978-0-7695-3763-4
PY 2009
BP 160
EP 164
DI 10.1109/DEXA.2009.90
PG 5
WC Computer Science, Information Systems; Computer Science, Theory &
Methods
SC Computer Science
GA BNV26
UT WOS:000275655300031
ER
PT J
AU Anderson, WR
Conner, CB
AF Anderson, William R.
Conner, Clint B.
TI Comparison of gas-phase mechanisms applied to RDX combustiori model
SO PROCEEDINGS OF THE COMBUSTION INSTITUTE
LA English
DT Article
DE Solid propellants; Burning rates; Kinetics mechanisms; Modeling
ID FLAME STRUCTURE; DECOMPOSITION; PROPELLANTS
AB Two detailed gas-phase chemical mechanisms for RDX - Yetter and coworkers, herein 'Y2' [K. Prasad. R.A. Yetter, M.D. Smooke, Combust. Sci. Technol. 124 (1997) p. 35.] Cal. Tech. group, herein 'CTM' [(a) A.D. Chakraborty, R.P. Muller, S. Dasgupta, W.A. Goddard, III, J. Phys. Chem. A 104 (2000) 2261. (b) D. Chakraborty, R.P. Muller, S. Dasgupta, W.A. Goddard. III, J. Comput. Aided Mater. Des. 8 (2001) 203. (c) D. Chakraborty, R.P. Muller. S. Dasgupta. W.A. Goddard, III, Available from: http://www.wag.caltech.edu/home/rpm/projects/hedm/] - have been tested using a recently developed combustion model. The results are compared with each other and experimental data. Burning rates predicted using CTM are about 15%, higher than Y2, but both compare well with experimental data across a wide pressure range. Also. majority species profiles tire in reasonable agreement with data from a 0.5 atm pressure experiment. However, comparison of predicted trace species profiles to experiments indicates neither mechanism reproduces all measured trace species well: furthermore, most of these trace species Occur along main reaction pathways. Detailed chemical analysis indicates the main initial RDX reaction is surprisingly very different for the two mechanisms. NO(2) scission dominates using Y2, but HONO elimination dominates using CTM in spite of the NO(2) scission reaction having by far the largest RDX decomposition rate coefficient in each mechanism. Analysis shows the unexpected result using CTM is due to a Curious global kinetics phenomenon arising in the product pathway: the ring-opening reaction, RDXR -> RDXRO, where RDXR is the cyclic radical formed upon NO(2) scission, has a much smaller rate coefficient in CTM compared to Y2. This causes the reaction to be a bottleneck, and so the NO(2) scission reaction goes into partial equilibrium rather than being forwards. Tests were performed to see how the predicted burning rates would be affected by changes in some of the most sensitive rate parameters. Some of the key parameters leading to the differing predictions have been identified. These results will help guide future efforts to understand and develop an accurate representation of the actual RDX combustion chemistry. (C) 2009 The Combustion Institute. Published by Elsevier Inc. All rights reserved.
C1 [Anderson, William R.; Conner, Clint B.] USA, Res Lab, Prop Sci Branch, AMSRD ARL WM BD, Aberdeen Proving Ground, MD 21005 USA.
RP Anderson, WR (reprint author), USA, Res Lab, Prop Sci Branch, AMSRD ARL WM BD, Bldg 4600, Aberdeen Proving Ground, MD 21005 USA.
EM willie@arl.army.mil; conner.c@maplan.com
FU Oak Ridge Associated Universities through a contract with the U.S. Army
Research Laboratory; ARL Major Shared Resource Center (MSRC)
[ARLAP02642500]
FX C.B.C. was supported by an appointment to the U.S. Army Research
Laboratory Postdoctoral Fellowship Program administered by the Oak Ridge
Associated Universities through a contract with the U.S. Army Research
Laboratory. We are grateful to Dr. Chiung-Chu Chen and Prof. Joseph W.
Bozzelli for enlightening discussions. We thank the ARL Major Shared
Resource Center (MSRC) for computer time under project #ARLAP02642500.
NR 20
TC 12
Z9 12
U1 2
U2 12
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1540-7489
J9 P COMBUST INST
JI Proc. Combust. Inst.
PY 2009
VL 32
BP 2123
EP 2130
DI 10.1016/j.proci.2008.05.023
PG 8
WC Thermodynamics; Energy & Fuels; Engineering, Chemical; Engineering,
Mechanical
SC Thermodynamics; Energy & Fuels; Engineering
GA 427CH
UT WOS:000264756900059
ER
PT J
AU Conner, CB
Anderson, WR
AF Conner, Clint B.
Anderson, William R.
TI Modeling the combustion of JA2 and solid propellants of similar
composition
SO PROCEEDINGS OF THE COMBUSTION INSTITUTE
LA English
DT Article
DE Solid propellants; Burning rates; Modeling
AB A theoretical study on combustion of JA2, RPD-380, and RPD-351, which are modified double-base propellants composed primarily of three identical nitrate ester ingredients, is presented. A one-dimensional, two-phase model was used [M.S. Miller, W.R. Anderson, in: V. Yang, T.B. Brill, W.Z. Ren (Eds.), Solid Propellant Combustion Chemistry, Combustion and Motor Interior Ballistics, Progress in Astronautics and Aeronautics, vol. 185. AIAA, Reston, VA, 2000 pp. 501-531, (a) M.S. Miller, W.R. Anderson, J. Propul Power 20(3) (2004) 440-454. (b) M.S. Miller, W.R. Anderson, CYCLOPS, A Breakthrough Code to Predict Solid-Propellant Burning Rates, U.S. Army Research Laboratory Technical Report, 1987 ARL-TR-2910.]. This approach has been shown to give good agreement between predicted and experimental results for several nitrate ester propellants, including JA2 [(a) M.S. Miller, W.R. Anderson, J. Propul. Power 20 (3) (2004) 440-454. (b) M.S. Miller, W.R. Anderson, CYCLOPS, A Breakthrough Code to Predict Solid-Propellant Burning Rates, U.S. Army Research Laboratory Technical Report, 1987 ARL-TR-2910.]. Extension of the model to the two RPD variants yields results in good agreement with existing experimental data. Comparisons of the response of predicted burning rates to experimental formulation changes at gun pressures, and to the initial propellant temperature are particularly encouraging. Our results show the burning rate ordering of these propellants is JA2 < RPD-380 < RPD-351 at all pressures. Chemistry which appears to account for this ordering is discussed. Also, an upgraded mechanism Was used, and the reasons for some slight changes in results vs. an older one are identified. Sensitivities of the computed temperatures near the propellant surface to the various reactions' rate coefficients are discussed; these provide insights regarding which reactions are centrally important to the computed burning rates and solutions. The spatial structure of one propellant flame - temperature and species profiles - is given; variations vs. the formulations and pressure are discussed. The fidelity of burning rate response to mixture ratio and initial propellant temperature are encouraging that the model may find application in propellant formulation science and elsewhere. (C) 2009 The Combustion Institute. Published by Elsevier Inc. All rights reserved.
C1 [Conner, Clint B.; Anderson, William R.] USA, Res Lab, Prop Sci Branch, AMSRD ARL WM BD, Aberdeen Proving Ground, MD 21005 USA.
RP Anderson, WR (reprint author), USA, Res Lab, Prop Sci Branch, AMSRD ARL WM BD, Bldg 4600, Aberdeen Proving Ground, MD 21005 USA.
EM conner.c@maplan.com; willie@arl.army.mil
FU Oak Ridge Associated Universities through a contract with the U.S. Army
Research Laboratory; ARL Major Shared Resource Center (MSRC)
[ARLAP02642500]
FX CBC was supported by an appointment to the U.S. Army Research Laboratory
Postdoctoral Fellowship Program administered by the Oak Ridge Associated
Universities through a contract with the U.S. Army Research Laboratory.
We thank the ARL Major Shared Resource Center (MSRC) for allowing use of
their computer time under project #ARLAP02642500.
NR 14
TC 1
Z9 1
U1 2
U2 5
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1540-7489
J9 P COMBUST INST
JI Proc. Combust. Inst.
PY 2009
VL 32
BP 2131
EP 2137
DI 10.1016/j.proci.2008.06.059
PG 7
WC Thermodynamics; Energy & Fuels; Engineering, Chemical; Engineering,
Mechanical
SC Thermodynamics; Energy & Fuels; Engineering
GA 427CH
UT WOS:000264756900060
ER
PT J
AU Federici, JA
Wetzel, ED
Geil, BR
Vlachos, DG
AF Federici, J. A.
Wetzel, E. D.
Geil, B. R.
Vlachos, D. G.
TI Single channel and heat recirculation catalytic microburners: An
experimental and computational fluid dynamics study
SO PROCEEDINGS OF THE COMBUSTION INSTITUTE
LA English
DT Article
DE Propane; Catalytic microcombustion; Stability; Heat recirculation;
Optimal catalyst placement
ID PROPANE/AIR MICROFLAME STABILITY; COMBUSTION; MICROREACTORS; GENERATION;
MIXTURES; SYSTEMS; REACTOR; BURNER; CFD
AB The stability of C(3)H(8)/air mixtures on Pt in single channel and heat recirculation catalytic microburners is compared experimentally using a microreactor capable of operating in both modes. The stability is further studied using Computational fluid dynamics Simulations, where the material properties of the burner can be systematically changed. It is shown through both experiments and simulation that catalytic heat recirculation burners have similar stability to single channel burners in the limit of highly conductive walls. In contrast, for low conductivity walls, heat recirculation proves to be effective at increasing combustion stability relative to single channel burners. Increasing the flow rate significantly extends the fuel lean extinction limit at low inlet velocities. Finally, optimal catalyst placement in heat recirculating burners is discussed. (C) 2009 The Combustion Institute. Published by Elsevier Inc. All rights reserved.
C1 [Federici, J. A.; Vlachos, D. G.] Univ Delaware, Ctr Catalyt Sci & Technol CCST, Dept Chem Engn, Newark, DE 19716 USA.
[Federici, J. A.; Vlachos, D. G.] Univ Delaware, Ctr Composite Mat CCM, Colburn Lab 353, Newark, DE 19716 USA.
[Wetzel, E. D.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
[Geil, B. R.] USA, Res Lab, Adelphi, MD 20783 USA.
RP Vlachos, DG (reprint author), Univ Delaware, Ctr Catalyt Sci & Technol CCST, Dept Chem Engn, Colburn Lab 353,150 Acad St, Newark, DE 19716 USA.
EM federici@udel.edu; vlachos@udel.edu
OI Vlachos, Dionisios/0000-0002-6795-8403
FU Army Research Laboratory [W911NF-06-2-0011]
FX Research was sponsored by the Army Research Laboratory and was
accomplished under Cooperative Agreement Number W911NF-06-2-0011. The
views and conclusions contained in this document are those of the
authors and should not be interpreted as representing the official
policies, either expressed or implied, of the Army Research Laboratory
or the U.S. Government. The U.S. Government IS authorized to reproduce
and distribute reprints for Government purposes notwithstanding any
copyright notation heron. J.A.F. would also like to thank Dr. Ayman
Karim for his assistance with the TEM.
NR 22
TC 24
Z9 26
U1 3
U2 8
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1540-7489
J9 P COMBUST INST
JI Proc. Combust. Inst.
PY 2009
VL 32
BP 3011
EP 3018
DI 10.1016/j.proci.2008.07.005
PG 8
WC Thermodynamics; Energy & Fuels; Engineering, Chemical; Engineering,
Mechanical
SC Thermodynamics; Energy & Fuels; Engineering
GA 427CH
UT WOS:000264756900164
ER
PT B
AU Corron, NJ
Reed, BR
Blakely, JN
Myneni, K
Pethel, SD
AF Corron, Ned J.
Reed, Billy R.
Blakely, Jonathan N.
Myneni, Krishna
Pethel, Shawn D.
GP IEEE
TI Chaotic Scrambling for Wireless Analog Video
SO PROCEEDINGS OF THE IEEE SOUTHEASTCON 2009, TECHNICAL PROCEEDINGS
LA English
DT Proceedings Paper
CT IEEE SoutheastCon 2009
CY MAR 05-08, 2009
CL Atlanta, GA
SP IEEE Reg 3, IEEE Atlanta Sect, Georgia Tech IEEE Student Branch
ID SYNCHRONIZATION
AB We report the implementation of a novel in-band chaotic scrambler for securing wireless analog video. In this demonstration system, an analog video signal is injected into a chaotic oscillator and the output is transmitted through a standard wireless radio link. At the receiver, a descrambler separates the video from the chaotic signal in real time. Experimental results show the scrambled signal effectively hides the original video image, yet the descrambler recovers the original color video with reasonable clarity and detail. Compared to digital encryption, chaotic scrambling offers an efficient, low-cost alternative for masking time-critical analog communications.
C1 [Corron, Ned J.; Blakely, Jonathan N.; Myneni, Krishna; Pethel, Shawn D.] US Army, RDECOM, Washington, DC USA.
[Reed, Billy R.] Sci Applicat Int Corp, Mclean, VA USA.
RP Corron, NJ (reprint author), US Army, RDECOM, Washington, DC USA.
EM ned.corron@us.army.mil; billy.r.reed@saic.com;
jonathan.blakely@us.army.mil; krishna.myneni@us.army.mil;
shawn.pethel@us.army.mil
OI Corron, Ned/0000-0002-3232-5024; Blakely, Jonathan/0000-0002-9772-582X
NR 9
TC 1
Z9 1
U1 0
U2 0
PU IEEE
PI NEW YORK
PA 345 E 47TH ST, NEW YORK, NY 10017 USA
BN 978-1-4244-3977-5
PY 2009
BP 38
EP +
PG 2
WC Engineering, Multidisciplinary
SC Engineering
GA BMM93
UT WOS:000272863900008
ER
PT B
AU Cetin, B
Bikdash, M
McInerney, M
AF Cetin, B.
Bikdash, M.
McInerney, M.
GP IEEE
TI Automated Electric Utility Pole Detection from Aerial Images
SO PROCEEDINGS OF THE IEEE SOUTHEASTCON 2009, TECHNICAL PROCEEDINGS
LA English
DT Proceedings Paper
CT IEEE SoutheastCon 2009
CY MAR 05-08, 2009
CL Atlanta, GA
SP IEEE Reg 3, IEEE Atlanta Sect, Georgia Tech IEEE Student Branch
AB This paper presents an algorithm for the recognition of similar electrical poles from an aerial image by detecting the pole shadow. One pole is used as a template (already identified by a human operator) for the algorithm. The algorithm includes feature extraction, candidate position determination, and elimination of redundant candidates. First, features of a pole shadow are extracted using standard filters and image processing techniques. Then the extracted features are used to design convolution filters tailored to emphasize possible locations for the shadows. Subsequently, an image candidate is submitted to Radon Transformation to verify adherence to expected shadow characteristics. Simulations show that most poles are made much more noticeable by the algorithm.
C1 [Cetin, B.; Bikdash, M.] NC A&T State Univ, Greensboro, NC 27411 USA.
[McInerney, M.] US Army, CERL, Mississippi State, MS USA.
RP Cetin, B (reprint author), NC A&T State Univ, Greensboro, NC 27411 USA.
EM bcetin@ncat.edu; bikdash@ncat.edu;
Michael.K.McInerney@erdc.usace.army.mil
FU Army Construction Engineering Research Laboratory (CERL)
[W1932T-06-P-0093]
FX This work has been supported by the Army Construction Engineering
Research Laboratory (CERL) under contracts W1932T-06-P-0093. We
appreciate their support.
NR 12
TC 2
Z9 2
U1 0
U2 0
PU IEEE
PI NEW YORK
PA 345 E 47TH ST, NEW YORK, NY 10017 USA
BN 978-1-4244-3977-5
PY 2009
BP 44
EP +
PG 2
WC Engineering, Multidisciplinary
SC Engineering
GA BMM93
UT WOS:000272863900009
ER
PT S
AU Sano, T
Chin, ESC
Paliwal, E
Chen, MW
AF Sano, T.
Chin, E. S. C.
Paliwal, E.
Chen, M. W.
BE Bansal, NP
Singh, JP
TI COMPARISON OF SLIP CAST TO HOT PRESSED BORON CARBIDE
SO PROCESSING AND PROPERTIES OF ADVANCED CERAMICS AND COMPOSITES
SE Ceramic Transactions
LA English
DT Proceedings Paper
CT Materials Science and Technology Conference and Exhibition (MS&T 08)
CY OCT 05-09, 2008
CL Pittsburgh, PA
ID CERAMICS
AB To meet the possible increase in future demand for armor materials, an increase in the throughput during manufacturing is necessary One possibility is the use of the slip casting and sintering technique to form ceramic armor compacts as an alternative to current hot pressing techniques Dynamic uniaxial compression tests with the Kolsky bar were conducted on two types of slip cast boron carbide, and compared with results from the standard hot pressed boron carbide One type was slip cast, sintered, and hot isostatically pressed, while the other was only slip cast and sintered Microstructural characterization by transmission electron microscopy showed graphite inclusions and more annealing twins than in the hot pressed boron carbide material Examination of fragments recovered from the compression tests determined that the fracture mode of both slip cast materials was brittle transgranular cleavage The compression test results show comparable compressive strengths between the sip cast and hot pressed boron carbide despite higher density of graphite in the slip cast material
C1 [Sano, T.; Chin, E. S. C.] USA, Res Lab, Aberdeen Proving Ground, MD USA.
[Paliwal, E.] Johns Hopkins Univ, Dept MEch Engn, Baltimore, MD USA.
[Chen, M. W.] Johns Hopkins Univ, Inst Mat Res, Baltimore, MD USA.
RP Sano, T (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD USA.
NR 8
TC 2
Z9 2
U1 0
U2 6
PU AMER CERAMIC SOC
PI WESTERVILLE
PA 735 CERAMIC PLACE, WESTERVILLE, OH 43081-8720 USA
SN 1042-1122
BN 978-0-470-40845-2
J9 CERAM TRANS
PY 2009
VL 203
BP 107
EP +
DI 10.1002/9780470522189.ch10
PG 2
WC Materials Science, Ceramics; Materials Science, Composites
SC Materials Science
GA BSU33
UT WOS:000285825100010
ER
PT S
AU West, BJ
AF West, Bruce J.
BE Sternad, D
TI Control from an Allometric Perspective
SO PROGRESS IN MOTOR CONTROL: A MULTIDISCIPLINARY PERSPECTIVE
SE Advances in Experimental Medicine and Biology
LA English
DT Article; Proceedings Paper
CT 5th Conference on Progress in Motor Control - A Multidisciplinary
Perspective
CY AUG 19-22, 2005
CL Penn State Univ, University Pk, PA
HO Penn State Univ
ID HUMAN GAIT; FRACTIONAL CALCULUS; HEARTBEAT; DYNAMICS; WALKING
AB Control of complexity is one of the goals of medicine, in particular, understanding and controlling physiological networks in order to ensure their proper operation. I have attempted to emphasize the difference between homeostatic control and allometric control mechanisms. Homeostatic control is familiar and has as its basis a negative feedback character, which is both local and relatively fast. Allometric control, on the other hand, is a new concept that can take into account long-time memory, correlations that are inverse power law in time, as well as long-range interactions in complex phenomena as manifest by inverse power-law distributions in the system variable. Allometric control introduces the fractal character into otherwise featureless random time series to enhance the robustness of physiological networks by introducing the fractional calculus into the control of the networks.
C1 USA, Res Off, Math & Informat Sci Directorate, Res Triangle Pk, NC 27709 USA.
RP West, BJ (reprint author), USA, Res Off, Math & Informat Sci Directorate, Res Triangle Pk, NC 27709 USA.
EM Bruce.J.West@us.army.mil
NR 32
TC 6
Z9 6
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES
SN 0065-2598
BN 978-0-387-77063-5
J9 ADV EXP MED BIOL
JI Adv.Exp.Med.Biol.
PY 2009
VL 629
BP 57
EP 82
DI 10.1007/978-0-387-77064-2_4
PG 26
WC Medicine, Research & Experimental; Neurosciences
SC Research & Experimental Medicine; Neurosciences & Neurology
GA BIT63
UT WOS:000262627200004
PM 19227495
ER
PT J
AU Kocifaj, M
Videen, G
AF Kocifaj, Miroslav
Videen, Gorden
TI Antenna design via inverse beamforming
SO PRZEGLAD ELEKTROTECHNICZNY
LA English
DT Article
DE beamforming; antenna design; electromagnetic radiation; dipoles
ID STEERED ARRAY-ANTENNA
AB The electromagnetic power generated by a linear phased-array system of radiating dipoles is analyzed theoretically. We introduce the concept of forced phase shift for any pair of dipoles, thus enabling wide-range adaptability of the antenna beam pattern. The exact solution of the electromagnetic power results in a set of formulae that can be used to solve the inverse problem of determining the optimum configuration of the phase shifts. Such a configuration guarantees that a modeled distribution of the radiating powers coincides with the predefined requirements as well as possible. Discretization of the continuous model is adopted so the optimum solution can be found for selected zones in the vicinity of the source of radiation
C1 [Kocifaj, Miroslav] Slovak Acad Sci, ICA, Bratislava 84503, Slovakia.
[Videen, Gorden] USA, Res Lab, AMSRD ARL CI ES, Adelphi, MD 20783 USA.
RP Kocifaj, M (reprint author), Slovak Acad Sci, ICA, Dubravska Cesta 9, Bratislava 84503, Slovakia.
EM kocifaj@savba.sk; gvideen@arl.army.mil
NR 10
TC 0
Z9 0
U1 0
U2 0
PU WYDAWNICTWO SIGMA - N O T
PI WARSAW
PA UL RATUSZOWA 11,, 00-950 WARSAW, POLAND
SN 0033-2097
J9 PRZ ELEKTROTECHNICZN
JI Prz. Elektrotechniczny
PY 2009
VL 85
IS 7
BP 49
EP 53
PG 5
WC Engineering, Electrical & Electronic
SC Engineering
GA 466AX
UT WOS:000267633700010
ER
PT J
AU Brunye, TT
Ditman, T
Mahoney, CR
Augustyn, JS
Taylor, HA
AF Brunye, Tad T.
Ditman, Tali
Mahoney, Caroline R.
Augustyn, Jason S.
Taylor, Holly A.
TI When You and I Share Perspectives Pronouns Modulate Perspective Taking
During Narrative Comprehension
SO PSYCHOLOGICAL SCIENCE
LA English
DT Article
ID LANGUAGE COMPREHENSION; SITUATION MODELS; MEMORY; ACCESSIBILITY;
INFORMATION
AB Readers mentally simulate the objects and events described in narratives. One common assumption is that readers mentally embody an actor's perspective; alternatively, readers might mentally simulate events from an external "onlooker" perspective. Two experiments examined the role of pronouns in modulating a reader's adopted perspective when comprehending simple event sentences. Experiment 1 demonstrated that readers embody an actor's perspective when the pronoun you or I is used, but take an external perspective when he is used. Experiment 2, however, found that a short discourse context preceding the event sentence led readers to adopt an external perspective with the pronoun I. These experiments demonstrate that pronoun variation and discourse context mediate the degree of embodiment experienced during narrative comprehension: In all cases, readers mentally simulate objects and events, but they embody an actor's perspective only when directly addressed as the subject of a sentence.
C1 [Brunye, Tad T.; Mahoney, Caroline R.; Augustyn, Jason S.] USA, NSRDEC, Attn AMSRD NSC WS P, Natick, MA 01760 USA.
[Brunye, Tad T.; Ditman, Tali; Mahoney, Caroline R.; Taylor, Holly A.] Tufts Univ, Medford, MA 02155 USA.
[Ditman, Tali] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Athinoula A Martinos Ctr Biomed Imaging, Cambridge, MA 02138 USA.
RP Brunye, TT (reprint author), USA, NSRDEC, Attn AMSRD NSC WS P, 15 Kansas St, Natick, MA 01760 USA.
EM tbrunye@alumni.tufts.edu
RI 江, 鈺麒/G-1379-2014
NR 22
TC 66
Z9 66
U1 2
U2 16
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 0956-7976
J9 PSYCHOL SCI
JI Psychol. Sci.
PD JAN
PY 2009
VL 20
IS 1
BP 27
EP 32
DI 10.1111/j.1467-9280.2008.02249.x
PG 6
WC Psychology, Multidisciplinary
SC Psychology
GA 392EH
UT WOS:000262285200006
PM 19076318
ER
PT S
AU Brandt, HE
AF Brandt, Howard E.
BE Donkor, EJ
Pirich, AR
Brandt, HE
TI Riemann Curvature in Quantum Computational Geometry
SO QUANTUM INFORMATION AND COMPUTATION VII
SE Proceedings of SPIE
LA English
DT Proceedings Paper
CT Conference on Quantum Information and Computation VII
CY APR 16-17, 2009
CL Orlando, FL
SP SPIE
DE quantum computing; quantum circuits; quantum complexity; differential
geometry; Riemannian geometry; curvature; geodesics
AB In the Riemannian geometry of quantum computation, the quantum evolution is described in terms of the special unitary group SU(2(n)) of n-qubit unitary operators with unit determinant. To elaborate on one aspect of the methodology, the Riemann curvature and sectional curvature are explicitly derived using the Lie algebra su(2(n)). This is important for investigations of the global characteristics of geodesic paths in the group manifold.
C1 USA, Res Lab, Adelphi, MD USA.
RP Brandt, HE (reprint author), USA, Res Lab, Adelphi, MD USA.
EM hbrandt@arl.army.mil
NR 22
TC 0
Z9 0
U1 0
U2 1
PU SPIE-INT SOC OPTICAL ENGINEERING
PI BELLINGHAM
PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
SN 0277-786X
BN 978-0-8194-7608-1
J9 PROC SPIE
PY 2009
VL 7342
AR 734208
DI 10.1117/12.820876
PG 11
WC Computer Science, Hardware & Architecture; Optics
SC Computer Science; Optics
GA BCS48
UT WOS:000311280400006
ER
PT S
AU Brandt, HE
AF Brandt, Howard E.
BE Donkor, EJ
Pirich, AR
Brandt, HE
TI Aspects of Quantum Computational Geodesics
SO QUANTUM INFORMATION AND COMPUTATION VII
SE Proceedings of SPIE
LA English
DT Proceedings Paper
CT Conference on Quantum Information and Computation VII
CY APR 16-17, 2009
CL Orlando, FL
SP SPIE
DE quantum computing; quantum circuits; quantum complexity; Riemannian
geometry; quantum computational geodesics
AB The object of this paper is to mathematically investigate characteristics of a geodesic equation describing possible minimum complexity paths in the special unitary group manifold representing the unitary evolution of n qubits associated with a quantum computation. Simple solutions are elaborated for the case of three qubits.
C1 USA, Res Lab, Adelphi, MD USA.
RP Brandt, HE (reprint author), USA, Res Lab, Adelphi, MD USA.
EM hbrandt@arl.army.mil
NR 26
TC 0
Z9 0
U1 0
U2 2
PU SPIE-INT SOC OPTICAL ENGINEERING
PI BELLINGHAM
PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
SN 0277-786X
BN 978-0-8194-7608-1
J9 PROC SPIE
PY 2009
VL 7342
AR 734205
DI 10.1117/12.817331
PG 11
WC Computer Science, Hardware & Architecture; Optics
SC Computer Science; Optics
GA BCS48
UT WOS:000311280400004
ER
PT J
AU Floersheim, RB
Hou, G
Firestone, K
AF Floersheim, R. Bruce
Hou, Gene
Firestone, Kent
TI CFPC material characteristics and SLS prototyping process
SO RAPID PROTOTYPING JOURNAL
LA English
DT Article
DE Polyamides; Composite materials; Sintering; Physical properties of
materials; Mechanical behaviour of materials
ID MECHANICAL-PROPERTIES
AB Purpose - The purpose of this paper is to characterize the material properties of carbon fiber polyamide composite (CFPC) used in a 3D rapid prototyping process based upon selective laser sintering (SLS) and demonstrate that the SLS process introduces a bias in the micro-fiber orientation such that the CFPC solid is an orthotropic structural material.
Design/methodology/approach - Material coupons for tensile tests from each of the orthogonal planes are created using the SLS process. After tensile testing, the coupons are examined under scanning electron microscopy to verify the micro-fiber orientation bias. A complex 3D structure developed utilizing the CFPC material is subjected to modal testing to extract the natural frequencies. These frequencies are compared to predictive numerical analysis results from computer-aided engineering (CAE) software to validate the coupon test results.
Findings - This paper proves that the CFPC solid material is orthotropic after the SLS process and that the process itself creates bias in the micro-fiber orientation. Predictions of natural frequencies from CAE software for a complex 3D structure created from CFPC are within 2 percent of the actual natural frequencies determined during modal testing.
Practical implications - The paper has determined the tensile material characteristics of solid CFPC correcting the original material data sheet information which lists the solid CFPC as isotropic with much stronger tensile characteristics. It has also provided evidence of the bias that SLS introduces to embedded micro-fibers during the rapid-prototyping process.
Originality/value - The paper deals with experimental work on determining the material characteristics of a relatively new composite material for which very little test data exists in literature. In particular, an original contribution is demonstration of the micro-fiber orientation bias introduced by the SLS process.
C1 [Floersheim, R. Bruce] US Mil Acad, W Chester, PA USA.
[Hou, Gene] Old Dominion Univ, Coll Engn & Technol, Norfolk, VA USA.
[Firestone, Kent] Solid Concepts Inc, Austin, TX USA.
RP Floersheim, RB (reprint author), US Mil Acad, W Chester, PA USA.
EM bruce.floersheim@us.army.mil
NR 14
TC 2
Z9 2
U1 0
U2 19
PU EMERALD GROUP PUBLISHING LIMITED
PI BINGLEY
PA HOWARD HOUSE, WAGON LANE, BINGLEY BD16 1WA, W YORKSHIRE, ENGLAND
SN 1355-2546
J9 RAPID PROTOTYPING J
JI Rapid Prototyping J.
PY 2009
VL 15
IS 5
BP 339
EP 345
DI 10.1108/13552540910993860
PG 7
WC Engineering, Mechanical; Materials Science, Multidisciplinary
SC Engineering; Materials Science
GA 515NU
UT WOS:000271479800005
ER
PT S
AU Readinger, ED
Metcalfe, GD
Shen, PH
Wraback, M
Jha, N
Woodward, N
Capek, P
Dierolf, V
AF Readinger, Eric D.
Metcalfe, Grace D.
Shen, Paul Hongen
Wraback, Michael
Jha, Naveen
Woodward, Nathaniel
Capek, Pavel
Dierolf, Volkmar
BE Dierolf, V
Fujiwara, Y
Hommerich, U
Ruterana, P
Zavada, JM
TI GaN Doped With Neodymium by Plasma-Assisted Molecular Beam Epitaxy for
Potential Lasing Applications
SO RARE-EARTH DOPING OF ADVANCED MATERIALS FOR PHOTONIC APPLICATIONS
SE Materials Research Society Symposium Proceedings
LA English
DT Proceedings Paper
CT Symposium on Rare-Earth Doping of Advanced Materials for Photonic
Applications held at the 2008 MRS Fall Meeting
CY DEC 01-04, 2008
CL Boston, MA
SP Mat Res Soc
ID INFRARED ELECTROLUMINESCENCE; ROOM-TEMPERATURE; THIN-FILMS;
PHOTOLUMINESCENCE; LUMINESCENCE; SPECTROSCOPY; ER
AB We provide an investigation of in situ doping of GaN with the RE element Nd by plasma assisted-molecular beam epitaxy (PA-MBE). GaN epilayers are grown on c-plane sapphire and free standing GaN substrates and the Nd doping is controlled by an effusion cell. The ideal growth conditions for Nd incorporation maintaining crystal quality in GaN were investigated. The optical absorption characteristics indicate that the GaN:Nd epilayer remains transparent at the Nd emission wavelength of interest. For the highest Nd effusion cell temperatures, Rutherford backscattering and secondary ion mass spectrometry data indicate similar to 5 at. % in epilayers grown on c-plane sapphire. X-ray diffraction found no evidence of phase segregation up to similar to 1 at. % Nd. The highest luminescence intensities correspond to a doping range 0.05-1 at. %, with the strongest emission occurring at 1.12 eV (1107 nm). We also present the Stark energy sublevels of Nd(3+) ions in GaN as determined by luminescence spectra. Photoluminescence excitation spectra reveal an optimal excitation energy of 1.48 eV (836 nm). We correlate the photoluminescence spectra with transitions from the (4)F(3/2) excited state to the (4)I(9/2), (4)I(11/2), and (4)I(13/2) multiplets of the Nd(3+) ion for above (325nm) and below (836nm) bandgap excitation. Spectral correlation of the Nd emission multiplets in addition to site-selective spectroscopy studies using combined excitation-emission spectroscopy with confocal microscopy indicate enhanced substantial doping at the Ga site compared to other techniques (ion implantation and co-sputtering).
C1 [Readinger, Eric D.; Metcalfe, Grace D.; Shen, Paul Hongen; Wraback, Michael] USA, Res Lab, Adelphi, MD 20783 USA.
RP Readinger, ED (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
NR 22
TC 0
Z9 0
U1 0
U2 0
PU MATERIALS RESEARCH SOCIETY
PI WARRENDALE
PA 506 KEYSTONE DRIVE, WARRENDALE, PA 15088-7563 USA
SN 0272-9172
BN 978-1-60511-083-7
J9 MATER RES SOC SYMP P
PY 2009
VL 1111
BP 17
EP 26
PG 10
WC Materials Science, Multidisciplinary
SC Materials Science
GA BMC23
UT WOS:000271829800003
ER
PT S
AU Ballal, P
Lewis, FL
Hudas, GR
AF Ballal, P.
Lewis, F. L.
Hudas, G. R.
BE Kyamakya, K
Halang, WA
Unger, H
Chedjou, JC
Rulkov, NF
Li, Z
TI Trust-Based Collaborative Control for Teams in Communication Networks
SO RECENT ADVANCES IN NONLINEAR DYNAMICS AND SYNCHRONIZATION: THEORY AND
APPLICATIONS
SE Studies in Computational Intelligence
LA English
DT Article; Book Chapter
ID AGENTS
C1 [Hudas, G. R.] USA, RDECOM TARDEC AMSRD TAR R, Warren, MI 48397 USA.
NR 20
TC 3
Z9 3
U1 0
U2 0
PU SPRINGER-VERLAG BERLIN
PI BERLIN
PA HEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY
SN 1860-949X
BN 978-3-642-04226-3
J9 STUD COMPUT INTELL
PY 2009
VL 254
BP 347
EP 363
D2 10.1007/978-3-642-04227-0
PG 17
WC Automation & Control Systems; Computer Science, Artificial Intelligence;
Physics, Mathematical
SC Automation & Control Systems; Computer Science; Physics
GA BLP57
UT WOS:000270731500011
ER
PT J
AU Cohen, SP
Dragovich, A
Hurley, R
Bajwa, ZH
AF Cohen, Steven P.
Dragovich, Anthony
Hurley, Robert
Bajwa, Zahid H.
TI Diagnosis of Facet joint Pain and Prediction of Success and Failure for
Cervical Facet Radiofrequency Denervation Reply
SO REGIONAL ANESTHESIA AND PAIN MEDICINE
LA English
DT Letter
ID MEDIAL BRANCH BLOCKS; MULTICENTER ANALYSIS; COST-EFFECTIVENESS;
INJECTIONS
C1 [Cohen, Steven P.; Hurley, Robert] Johns Hopkins Sch Med, Baltimore, MD USA.
[Cohen, Steven P.] Walter Reed Army Med Ctr, Baltimore, MD USA.
[Dragovich, Anthony] Womack Army Med Ctr, Ft Bragg, NC USA.
[Bajwa, Zahid H.] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Cambridge, MA 02138 USA.
RP Cohen, SP (reprint author), Johns Hopkins Sch Med, Baltimore, MD USA.
NR 15
TC 1
Z9 1
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1098-7339
J9 REGION ANESTH PAIN M
JI Region. Anesth. Pain Med.
PD JAN-FEB
PY 2009
VL 34
IS 1
BP 82
EP 83
PG 2
WC Anesthesiology
SC Anesthesiology
GA 399VW
UT WOS:000262828400031
ER
PT B
AU Brown, SI
AF Brown, Stephen I.
BE Sriraman, B
Goodchild, S
TI HUMOR IN E(A)RNEST
SO RELATIVELY AND PHILOSOPHICALLY EARNEST: FESTSCHRIFT IN HONOR OF PAUL
ERNEST'S 65TH BIRTHDAY
SE Montana Mathematics Enthusiast Monograph Series in Mathematics Education
LA English
DT Article; Book Chapter
C1 USA, Washington, DC 20310 USA.
RP Brown, SI (reprint author), USA, Washington, DC 20310 USA.
NR 33
TC 0
Z9 0
U1 0
U2 0
PU INFORMATION AGE PUBLISHING-IAP
PI CHARLOTTE
PA PO BOX 79049, CHARLOTTE, NC 28271-7047 USA
BN 978-1-60752-240-9
J9 MONT MATH ENTHUS MON
PY 2009
VL 8
BP 95
EP 126
PG 32
WC Education & Educational Research; Education, Scientific Disciplines;
Mathematics; Philosophy
SC Education & Educational Research; Mathematics; Philosophy
GA BLJ32
UT WOS:000270300900008
ER
PT B
AU Nelson, J
AF Nelson, Jeffery
BE Billingham, RP
Peters, WA
Kobashi, KC
TI Reoperations Within the First 30 Days After Pelvic Surgery
SO REOPERATIVE PELVIC SURGERY
LA English
DT Article; Book Chapter
ID SMALL-BOWEL OBSTRUCTION; POUCH-ANAL ANASTOMOSIS; LOW ANTERIOR RESECTION;
RANDOMIZED CONTROLLED-TRIAL; ABDOMINAL WOUND DEHISCENCE; VACUUM-ASSISTED
CLOSURE; RECTAL-CANCER; FOURNIERS GANGRENE; COLORECTAL SURGERY;
ABDOMINOPERINEAL RESECTION
C1 Walter Reed Army Med Ctr, Dept Surg, Washington, DC 20307 USA.
RP Nelson, J (reprint author), Walter Reed Army Med Ctr, Dept Surg, Washington, DC 20307 USA.
NR 70
TC 0
Z9 0
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES
BN 978-0-387-89998-5
PY 2009
BP 5
EP 14
DI 10.1007/b14187_2
D2 10.1007/b14187
PG 10
WC Obstetrics & Gynecology; Surgery; Urology & Nephrology
SC Obstetrics & Gynecology; Surgery; Urology & Nephrology
GA BLA02
UT WOS:000269719900002
ER
PT J
AU Yu, GL
Borlongan, CV
Stahl, CE
Hess, DC
Ou, YL
Kaneko, Y
Yu, SJ
Yang, TL
Fang, L
Xie, XM
AF Yu, Guolong
Borlongan, Cesar V.
Stahl, Christine E.
Hess, David C.
Ou, Yali
Kaneko, Yuji
Yu, Seong Jin
Yang, Tianlun
Fang, Li
Xie, Xiumei
TI Systemic delivery of umbilical cord blood cells for stroke therapy: A
review
SO RESTORATIVE NEUROLOGY AND NEUROSCIENCE
LA English
DT Review
DE Cerebral ischemia; adult stem cells; transplantation; neuroprotection;
neurorestoration
ID MESENCHYMAL STEM-CELLS; CENTRAL-NERVOUS-SYSTEM; NEURAL PROGENITOR CELLS;
CEREBRAL-ISCHEMIA MODEL; MARROW STROMAL CELLS; HUMAN HEMATOPOIETIC STEM;
BONE-MARROW; RAT MODEL; IN-VITRO; NEURONAL DIFFERENTIATION
AB Purpose: This review paper summarizes relevant studies, discusses potential mechanisms of transplanted cell-mediated neuroprotection, and builds a case for the need to establish outcome parameters that are critical for transplantation success. In particular, we outline the advantages and disadvantages of systemic delivery of human umbilical cord blood (HUCB) cells in the field of cellular transplantation for treating ischemic stroke.
Methods: A MEDLINE/PubMed systematic search of published articles in peer-reviewed journals over the last 25 years was performed focusing on the theme of HUCB as donor graft source for transplantation therapy in neurological disorders with emphasis on stroke.
Results: Ischemic stroke remains a leading cause of human death and disability. Although stroke survivors may gain spontaneous partial functional recovery, they often suffer from sensory-motor dysfunction, behavioral/neurological alterations, and various degrees of paralysis. Currently, limited clinical intervention is available to prevent ischemic damage and restore lost function in stroke victims. Stem cells from fetal tissues, bone marrow, and HUCB has emerged in the last few years as a potential cell transplant cell source for ischemic stroke, because of their capability to differentiate into multiple cell types and the possibility that they may provide trophic support for cell survival, tissue repair, and functional recovery.
Conclusion: A growing number of studies highlight the potential of systemic delivery of HUCB cells as a novel therapeutic approach for stroke. However, additional preclinical studies are warranted to reveal the optimal HUCB transplant regimen that is safe and efficacious prior to proceeding to large-scale clinical application of these cells for stroke therapy.
C1 [Yu, Guolong; Ou, Yali; Yang, Tianlun; Fang, Li; Xie, Xiumei] Cent S Univ, Xiangya Hosp, Dept Cardiol, Changsha 410008, Hunan, Peoples R China.
[Borlongan, Cesar V.; Hess, David C.; Kaneko, Yuji; Yu, Seong Jin] Med Coll Georgia, Dept Neurol, Augusta, GA 30912 USA.
[Stahl, Christine E.] Dwight D Eisenhower Army Med Ctr, Dept Internal Med, Ft Gordon, GA USA.
RP Yu, GL (reprint author), Cent S Univ, Xiangya Hosp, Dept Cardiol, Changsha 410008, Hunan, Peoples R China.
EM yuguolong123@yahoo.com.cn; cborlongan@mail.mcg.edu
RI Kaneko, Yuji/J-6447-2012;
OI Borlongan, Cesar/0000-0002-2966-9782
FU National Natural Science Foundation of China; NIH [NINDS
1U01NS055914-01, NINDS 2R42NS055606-02]; MCG Department of Neurology
Funds
FX Drs. Yu, Ou, Yang, and Fang were funded by the National Natural Science
Foundation of China, whereas Drs. Borlongan and Hess were supported by
NIH NINDS 1U01NS055914-01, NIH NINDS 2R42NS055606-02, and the MCG
Department of Neurology Funds.
NR 92
TC 19
Z9 25
U1 0
U2 6
PU IOS PRESS
PI AMSTERDAM
PA NIEUWE HEMWEG 6B, 1013 BG AMSTERDAM, NETHERLANDS
SN 0922-6028
J9 RESTOR NEUROL NEUROS
JI Restor. Neurol. Neurosci.
PY 2009
VL 27
IS 1
BP 41
EP 54
DI 10.3233/RNN-2009-0460
PG 14
WC Neurosciences
SC Neurosciences & Neurology
GA 400NV
UT WOS:000262876000004
PM 19164852
ER
PT J
AU Gumz, JE
AF Gumz, Jonathan E.
BA Gumz, JE
BF Gumz, JE
TI The Resurrection and Collapse of Empire in Habsburg Serbia, 1914-1918
Introduction
SO RESURRECTION AND COLLAPSE OF EMPIRE IN HABSBURG SERBIA, 1914-1918
SE Cambridge Military Histories
LA English
DT Editorial Material; Book Chapter
C1 [Gumz, Jonathan E.] USN, War Coll, Stennis Space Ctr, MS USA.
[Gumz, Jonathan E.] Univ Wisconsin Milwaukee, Milwaukee, WI USA.
[Gumz, Jonathan E.] Univ Chicago, Chicago, IL 60637 USA.
RP Gumz, JE (reprint author), US Mil Acad, West Point, NY 10996 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU CAMBRIDGE UNIV PRESS
PI CAMBRIDGE
PA THE PITT BUILDING, TRUMPINGTON ST, CAMBRIDGE CB2 1RP, CAMBS, ENGLAND
BN 978-0-521-89627-6
J9 CAMBRIDGE MIL HIST
PY 2009
BP 1
EP +
PG 44
WC History
SC History
GA BBU11
UT WOS:000308168900001
ER
PT J
AU Gumz, JE
AF Gumz, Jonathan E.
BA Gumz, JE
BF Gumz, JE
TI Facing a Serb Levee en Masse: The Habsburg Army and War on Civilians in
1914
SO RESURRECTION AND COLLAPSE OF EMPIRE IN HABSBURG SERBIA, 1914-1918
SE Cambridge Military Histories
LA English
DT Article; Book Chapter
C1 [Gumz, Jonathan E.] USN, War Coll, Stennis Space Ctr, MS USA.
[Gumz, Jonathan E.] Univ Wisconsin Milwaukee, Milwaukee, WI USA.
[Gumz, Jonathan E.] Univ Chicago, Chicago, IL 60637 USA.
RP Gumz, JE (reprint author), US Mil Acad, West Point, NY 10996 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU CAMBRIDGE UNIV PRESS
PI CAMBRIDGE
PA THE PITT BUILDING, TRUMPINGTON ST, CAMBRIDGE CB2 1RP, CAMBS, ENGLAND
BN 978-0-521-89627-6
J9 CAMBRIDGE MIL HIST
PY 2009
BP 27
EP 61
PG 35
WC History
SC History
GA BBU11
UT WOS:000308168900002
ER
PT J
AU Gumz, JE
AF Gumz, Jonathan E.
BA Gumz, JE
BF Gumz, JE
TI Eradicating National Politics in Occupied Serbia
SO RESURRECTION AND COLLAPSE OF EMPIRE IN HABSBURG SERBIA, 1914-1918
SE Cambridge Military Histories
LA English
DT Article; Book Chapter
C1 [Gumz, Jonathan E.] USN, War Coll, Stennis Space Ctr, MS USA.
[Gumz, Jonathan E.] Univ Wisconsin Milwaukee, Milwaukee, WI USA.
[Gumz, Jonathan E.] Univ Chicago, Chicago, IL 60637 USA.
RP Gumz, JE (reprint author), US Mil Acad, West Point, NY 10996 USA.
NR 0
TC 2
Z9 2
U1 0
U2 0
PU CAMBRIDGE UNIV PRESS
PI CAMBRIDGE
PA THE PITT BUILDING, TRUMPINGTON ST, CAMBRIDGE CB2 1RP, CAMBS, ENGLAND
BN 978-0-521-89627-6
J9 CAMBRIDGE MIL HIST
PY 2009
BP 62
EP 104
PG 43
WC History
SC History
GA BBU11
UT WOS:000308168900003
ER
PT J
AU Gumz, JE
AF Gumz, Jonathan E.
BA Gumz, JE
BF Gumz, JE
TI Legal Severity, International Law, and the Tottering Empire in Occupied
Serbia
SO RESURRECTION AND COLLAPSE OF EMPIRE IN HABSBURG SERBIA, 1914-1918
SE Cambridge Military Histories
LA English
DT Article; Book Chapter
C1 [Gumz, Jonathan E.] USN, War Coll, Stennis Space Ctr, MS USA.
[Gumz, Jonathan E.] Univ Wisconsin Milwaukee, Milwaukee, WI USA.
[Gumz, Jonathan E.] Univ Chicago, Chicago, IL 60637 USA.
RP Gumz, JE (reprint author), US Mil Acad, West Point, NY 10996 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU CAMBRIDGE UNIV PRESS
PI CAMBRIDGE
PA THE PITT BUILDING, TRUMPINGTON ST, CAMBRIDGE CB2 1RP, CAMBS, ENGLAND
BN 978-0-521-89627-6
J9 CAMBRIDGE MIL HIST
PY 2009
BP 105
EP 141
PG 37
WC History
SC History
GA BBU11
UT WOS:000308168900004
ER
PT J
AU Gumz, JE
AF Gumz, Jonathan E.
BA Gumz, JE
BF Gumz, JE
TI Food as Salvation: Food Supply, the Monarchy, and Serbia, 1916-1918
SO RESURRECTION AND COLLAPSE OF EMPIRE IN HABSBURG SERBIA, 1914-1918
SE Cambridge Military Histories
LA English
DT Article; Book Chapter
C1 [Gumz, Jonathan E.] USN, War Coll, Stennis Space Ctr, MS USA.
[Gumz, Jonathan E.] Univ Wisconsin Milwaukee, Milwaukee, WI USA.
[Gumz, Jonathan E.] Univ Chicago, Chicago, IL 60637 USA.
RP Gumz, JE (reprint author), US Mil Acad, West Point, NY 10996 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU CAMBRIDGE UNIV PRESS
PI CAMBRIDGE
PA THE PITT BUILDING, TRUMPINGTON ST, CAMBRIDGE CB2 1RP, CAMBS, ENGLAND
BN 978-0-521-89627-6
J9 CAMBRIDGE MIL HIST
PY 2009
BP 142
EP 192
PG 51
WC History
SC History
GA BBU11
UT WOS:000308168900005
ER
PT J
AU Gumz, JE
AF Gumz, Jonathan E.
BA Gumz, JE
BF Gumz, JE
TI A Levee en Masse Nation No More? Guerrilla War in Habsburg Serbia
SO RESURRECTION AND COLLAPSE OF EMPIRE IN HABSBURG SERBIA, 1914-1918
SE Cambridge Military Histories
LA English
DT Article; Book Chapter
C1 [Gumz, Jonathan E.] USN, War Coll, Stennis Space Ctr, MS USA.
[Gumz, Jonathan E.] Univ Wisconsin Milwaukee, Milwaukee, WI USA.
[Gumz, Jonathan E.] Univ Chicago, Chicago, IL 60637 USA.
RP Gumz, JE (reprint author), US Mil Acad, West Point, NY 10996 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU CAMBRIDGE UNIV PRESS
PI CAMBRIDGE
PA THE PITT BUILDING, TRUMPINGTON ST, CAMBRIDGE CB2 1RP, CAMBS, ENGLAND
BN 978-0-521-89627-6
J9 CAMBRIDGE MIL HIST
PY 2009
BP 193
EP 230
PG 38
WC History
SC History
GA BBU11
UT WOS:000308168900006
ER
PT J
AU Gumz, JE
AF Gumz, Jonathan E.
BA Gumz, JE
BF Gumz, JE
TI The Resurrection and Collapse of Empire in Habsburg Serbia, 1914-1918
Conclusion
SO RESURRECTION AND COLLAPSE OF EMPIRE IN HABSBURG SERBIA, 1914-1918
SE Cambridge Military Histories
LA English
DT Editorial Material; Book Chapter
C1 [Gumz, Jonathan E.] USN, War Coll, Stennis Space Ctr, MS USA.
[Gumz, Jonathan E.] Univ Wisconsin Milwaukee, Milwaukee, WI USA.
[Gumz, Jonathan E.] Univ Chicago, Chicago, IL 60637 USA.
RP Gumz, JE (reprint author), US Mil Acad, West Point, NY 10996 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU CAMBRIDGE UNIV PRESS
PI CAMBRIDGE
PA THE PITT BUILDING, TRUMPINGTON ST, CAMBRIDGE CB2 1RP, CAMBS, ENGLAND
BN 978-0-521-89627-6
J9 CAMBRIDGE MIL HIST
PY 2009
BP 231
EP 248
PG 18
WC History
SC History
GA BBU11
UT WOS:000308168900007
ER
PT J
AU Adams, BD
Jones, RJ
Delgado, RE
Larkin, GL
AF Adams, Bruce D.
Jones, Robert J.
Delgado, Roxana E.
Larkin, Gregory Luke
CA Amer Heart Assoc Natl Registr
TI Cardiac arrests of hospital staff and visitors: Experience from the
national registry of cardiopulmonary resuscitation
SO RESUSCITATION
LA English
DT Article
DE Automated external defibrillator (AED); Cardiopulmonary resuscitation
(CPR); Emergency treatment; Medical Emergency Team; Return of
spontaneous circulation; Tracheal intubation; Utstein template;
Witnessed cardiac arrest
ID PUBLIC-ACCESS DEFIBRILLATION; AUTOMATED EXTERNAL DEFIBRILLATORS; MINUTES
COUNT; SURVIVAL; PROGRAM; NURSES; CARE; PROFESSIONALS; AREAS; TEAMS
AB Aim of the study: Approximately 750,000 in-hospital cardiac arrests occur annually in the United States. Many will occur to visitors or staff members within the hospital's public areas. We sought to provide a descriptive analysis of visitor cardiac arrests in hospitals and to compare survival outcomes to matching inpatient arrests.
Methods: We queried the National Registry of Cardiopulmonary Resuscitation (NRCPR (R)) for all adult cardiac arrests from January 2000 to May 2006 that occurred to visitors or employees anywhere within the hospital. Visitors were matched to inpatient cardiac arrests from within the same NRCPR database for age, gender, race, prior residence and functional status, and presenting rhythms. The compared outcomes were return of spontaneous circulation (ROSC), survival to 24 h (S24), and survival to discharge (SHD).
Results: 147 visitors suffered a cardiac arrest during the study period. S24 (48% vs. 37%, p=0.011) and SHD (42% vs. 24%, p<0.0001) were both higher in the visitor cohort. However, ROSC did not significantly differ between visitors and controls (57% vs. 51%). Visitor cardiac arrests occurred in a wide variety of locations.
Conclusion: Cardiac arrest among hospital visitors is a relatively common event. The survival outcomes of hospital visitors compared unfavorably to that of recently published experience with out-of-hospital cardiac arrest victims. Published by Elsevier Ireland Ltd
C1 [Adams, Bruce D.; Delgado, Roxana E.] William Beaumont Army Med Ctr, Dept Clin Invest, El Paso, TX 79920 USA.
[Jones, Robert J.] Brooke Army Med Ctr, Dept Emergency Med, San Antonio, TX USA.
[Larkin, Gregory Luke] Yale Univ, Sch Med, Dept Surg, Emergency Med Sect, New Haven, CT 06510 USA.
RP Adams, BD (reprint author), William Beaumont Army Med Ctr, Dept Clin Invest, 5005 N Piedras St, El Paso, TX 79920 USA.
EM bruce.adams@amedd.army.mil
NR 39
TC 5
Z9 6
U1 0
U2 1
PU ELSEVIER IRELAND LTD
PI CLARE
PA ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000,
IRELAND
SN 0300-9572
J9 RESUSCITATION
JI Resuscitation
PD JAN
PY 2009
VL 80
IS 1
BP 65
EP 68
DI 10.1016/j.resuscitation.2008.09.016
PG 4
WC Critical Care Medicine; Emergency Medicine
SC General & Internal Medicine; Emergency Medicine
GA 395SC
UT WOS:000262542800015
PM 19081663
ER
PT J
AU Bakari, M
Aboud, S
Nilsson, C
Francis, J
Buma, D
Moshiro, C
Aris, EA
Lyamuya, E
Janabi, M
Mbwana, J
Mwanyika, L
Stout, R
Hejdeman, B
Brave, A
Robb, M
Marovich, M
Michael, N
Earl, P
Moss, B
Wahren, B
Biberfeld, G
Pallangyo, K
Mhalu, F
Sandstrom, E
AF Bakari, M.
Aboud, S.
Nilsson, C.
Francis, J.
Buma, D.
Moshiro, C.
Aris, E. A.
Lyamuya, E.
Janabi, M.
Mbwana, J.
Mwanyika, L.
Stout, R.
Hejdeman, B.
Brave, A.
Robb, M.
Marovich, M.
Michael, N.
Earl, P.
Moss, B.
Wahren, B.
Biberfeld, G.
Pallangyo, K.
Mhalu, F.
Sandstrom, E.
TI A low dose of multigene, multiclade HIV DNA given intradermally induces
strong and broad immune responses after boosting with heterologous HIV
MVA
SO RETROVIROLOGY
LA English
DT Meeting Abstract
C1 [Bakari, M.; Aboud, S.; Francis, J.; Moshiro, C.; Lyamuya, E.; Mbwana, J.; Pallangyo, K.; Mhalu, F.] MUHAS, Dar Es Salaam, 20892, Tanzania.
[Nilsson, C.; Brave, A.; Wahren, B.; Biberfeld, G.] Swedish Inst Infect Dis Control, Stockholm, Sweden.
[Nilsson, C.; Brave, A.; Wahren, B.; Biberfeld, G.] Karolinska Inst, Stockholm, Sweden.
[Buma, D.; Aris, E. A.; Janabi, M.] Muhimbili Natl Hosp, Dar Es Salaam, Tanzania.
[Mwanyika, L.] Tanzania Police Force, Dar Es Salaam, Tanzania.
[Hejdeman, B.; Sandstrom, E.] Soder Sjukhuset, KI, Stockholm, Sweden.
[Robb, M.; Marovich, M.; Michael, N.] Walter Reed Army Inst Res, Rockville, MD USA.
[Earl, P.; Moss, B.] NIAID, NIH, Bethesda, MD USA.
NR 0
TC 1
Z9 1
U1 0
U2 0
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1742-4690
J9 RETROVIROLOGY
JI Retrovirology
PY 2009
VL 6
AR P403
PG 1
WC Virology
SC Virology
GA 509KL
UT WOS:000271015300454
ER
PT J
AU Beck, Z
Karasavvas, N
Matyas, GR
Alving, CR
AF Beck, Z.
Karasavvas, N.
Matyas, G. R.
Alving, C. R.
TI Membrane-specific antibodies that simultaneously bind to gp41 of HIV-1
and membrane lipid epitopes are induced by immunization with liposomes
SO RETROVIROLOGY
LA English
DT Meeting Abstract
C1 [Beck, Z.] Henry M Jackson Fdn US Mil HIV Res Program, Div Retrovirol, Dept Adjuvant & Antigen Res, Rockville, MD USA.
[Karasavvas, N.; Matyas, G. R.; Alving, C. R.] US Mil HIV Res Program, Walter Reed Army Inst Res, Rockville, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1742-4690
J9 RETROVIROLOGY
JI Retrovirology
PY 2009
VL 6
AR P174
PG 1
WC Virology
SC Virology
GA 509KL
UT WOS:000271015300225
ER
PT J
AU Eller, L
Ouma, B
Oballah, P
Eller, MA
de Souza, MS
Wabwire-Mangen, F
Laeyendecker, O
Quinn, T
Kiwanuka, N
Serwadda, D
Sewankambo, N
Wawer, M
Gray, R
Michael, NL
Robb, ML
Montefiori, D
Brown, BK
Polonis, VR
AF Eller, L.
Ouma, B.
Oballah, P.
Eller, M. A.
de Souza, M. S.
Wabwire-Mangen, F.
Laeyendecker, O.
Quinn, T.
Kiwanuka, N.
Serwadda, D.
Sewankambo, N.
Wawer, M.
Gray, R.
Michael, N. L.
Robb, M. L.
Montefiori, D.
Brown, B. K.
Polonis, V. R.
TI Breadth and magnitude of neutralizing antibody responses in subjects
infected with HIV-1 subtype D or recombinants in Rakai district, Uganda
SO RETROVIROLOGY
LA English
DT Meeting Abstract
C1 [Eller, L.; Eller, M. A.; Michael, N. L.; Robb, M. L.; Brown, B. K.; Polonis, V. R.] Makerere Univ, Walter Reed Project, US Mil HIV Res Program, Kampala, Uganda.
[de Souza, M. S.] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Wabwire-Mangen, F.; Kiwanuka, N.; Serwadda, D.] Makerere Univ, Walter Reed Makerere Univ, Sch Publ Hlth, Kampala, Uganda.
[Laeyendecker, O.; Quinn, T.; Wawer, M.; Gray, R.] NIAID, Johns Hopkins Sch Med, NIH, Baltimore, MD USA.
[Sewankambo, N.] Makerere Univ, Coll Hlth Sci, Kampala, Uganda.
[Montefiori, D.] Duke Univ, Durham, NC USA.
RI Laeyendecker, Oliver/B-9331-2009
NR 0
TC 0
Z9 0
U1 0
U2 0
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1742-4690
J9 RETROVIROLOGY
JI Retrovirology
PY 2009
VL 6
AR P56
PG 1
WC Virology
SC Virology
GA 509KL
UT WOS:000271015300109
ER
PT J
AU Eller, MA
Eller, L
Koehler, RN
Kijak, GH
Guwatudde, D
Marovich, MA
Michael, NL
de Souza, MS
Wabwire-Mangen, F
Robb, ML
Currier, JR
Sandberg, JK
AF Eller, M. A.
Eller, L.
Koehler, R. N.
Kijak, G. H.
Guwatudde, D.
Marovich, M. A.
Michael, N. L.
de Souza, M. S.
Wabwire-Mangen, F.
Robb, M. L.
Currier, J. R.
Sandberg, J. K.
TI Altered NK cell phenotype and function in Ugandans with chronic HIV-1
infection
SO RETROVIROLOGY
LA English
DT Meeting Abstract
C1 [Eller, M. A.; Eller, L.] Makerere Univ, Walter Reed Project, Kampala, Uganda.
[Koehler, R. N.; Kijak, G. H.; Marovich, M. A.; Michael, N. L.; Robb, M. L.; Currier, J. R.] US Mil HIV Res Program MHRP, Rockville, MD USA.
[Guwatudde, D.; Wabwire-Mangen, F.] Makerere Univ, Sch Publ Hlth, Makerere Univ Walter Reed, Kampala, Uganda.
[de Souza, M. S.] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Sandberg, J. K.] Karolinska Inst, Ctr Infect Med, Stockholm, Sweden.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1742-4690
J9 RETROVIROLOGY
JI Retrovirology
PY 2009
VL 6
AR P143
PG 1
WC Virology
SC Virology
GA 509KL
UT WOS:000271015300195
ER
PT J
AU Kaewkungwal, J
Pitisuttithum, P
Nitayapan, S
Khamboonruang, C
Khamboonruang, C
Thongchareon, P
Kunasol, P
Benenson, M
Kim, J
AF Kaewkungwal, J.
Pitisuttithum, P.
Nitayapan, S.
Khamboonruang, C.
Khamboonruang, C.
Thongchareon, P.
Kunasol, P.
Benenson, M.
Kim, J.
TI Assuring data quality of the phase III vaccine trial of ALVAC vaccine
priming and AIDSVAX vaccine boosting in Thailand
SO RETROVIROLOGY
LA English
DT Meeting Abstract
C1 [Kaewkungwal, J.; Pitisuttithum, P.; Thongchareon, P.] Mahidol Univ, Fac Trop Med, Dept Trop Hyg, Bangkok, Thailand.
[Nitayapan, S.] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Khamboonruang, C.; Khamboonruang, C.; Kunasol, P.] Minist Publ Hlth, Dept Dis Control, Nonthaburi, Thailand.
[Benenson, M.; Kim, J.] US Mil HIV Res Program, Rockville, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1742-4690
J9 RETROVIROLOGY
JI Retrovirology
PY 2009
VL 6
AR P215
PG 2
WC Virology
SC Virology
GA 509KL
UT WOS:000271015300266
ER
PT J
AU Matyas, GR
Wieczorek, L
Beck, Z
Ochsenbauer-Jambor, C
Kappes, JC
Michael, NL
Polonis, VR
Alving, CR
AF Matyas, G. R.
Wieczorek, L.
Beck, Z.
Ochsenbauer-Jambor, C.
Kappes, J. C.
Michael, N. L.
Polonis, V. R.
Alving, C. R.
TI Neutralizing antibodies induced by immunization with liposomal gp41
peptide simultaneously bind to both the 2F5 or 4E10 epitope and lipid
epitopes
SO RETROVIROLOGY
LA English
DT Meeting Abstract
C1 [Matyas, G. R.; Michael, N. L.; Polonis, V. R.; Alving, C. R.] Walter Reed Army Inst Res, Div Retrovirol, Rockville, MD USA.
[Wieczorek, L.; Beck, Z.] Henry M Jackson Fdn Advancement Mil Med, Rockville, MD USA.
[Ochsenbauer-Jambor, C.; Kappes, J. C.] Univ Alabama, Vet Affairs Med Ctr, Birmingham, AL USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1742-4690
J9 RETROVIROLOGY
JI Retrovirology
PY 2009
VL 6
AR P80
PG 1
WC Virology
SC Virology
GA 509KL
UT WOS:000271015300132
ER
PT J
AU Nilsson, C
Aboud, S
Karlen, K
Marovich, M
Wahren, B
Sandstrom, E
Gaines, H
Biberfeld, G
Godoy-Ramirez, K
AF Nilsson, C.
Aboud, S.
Karlen, K.
Marovich, M.
Wahren, B.
Sandstrom, E.
Gaines, H.
Biberfeld, G.
Godoy-Ramirez, K.
TI Strong HIV-specific CD4 and CD8 T-lymphocyte proliferation in HIV-1 DNA
prime/modified vaccinia virus Ankara (MVA)
SO RETROVIROLOGY
LA English
DT Meeting Abstract
C1 [Nilsson, C.; Karlen, K.; Wahren, B.; Gaines, H.; Biberfeld, G.; Godoy-Ramirez, K.] Karolinska Inst, Swedish Inst Infect Dis Control, Solna, Sweden.
[Aboud, S.] Muhimbili Univ Hlth & Allied Sci, Dar Es Salaam, Tanzania.
[Marovich, M.] Walter Reed Army Inst Res, Rockville, MD USA.
[Sandstrom, E.] Venhalsan & Karolinska Inst, Stockholm, Sweden.
NR 0
TC 1
Z9 1
U1 0
U2 0
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1742-4690
J9 RETROVIROLOGY
JI Retrovirology
PY 2009
VL 6
AR O26
PG 1
WC Virology
SC Virology
GA 509KL
UT WOS:000271015300027
ER
PT J
AU Peachman, K
Wieczorek, L
Polonis, VR
Alving, CR
Rao, M
AF Peachman, K.
Wieczorek, L.
Polonis, V. R.
Alving, C. R.
Rao, M.
TI Analysis of the binding of multiple clades of HIV-1 by a modified virus
capture assay
SO RETROVIROLOGY
LA English
DT Meeting Abstract
C1 [Peachman, K.; Wieczorek, L.] Henry M Jackson Fdn USMHRP, DAAR, Rockville, MD USA.
[Polonis, V. R.; Alving, C. R.; Rao, M.] Walter Reed Army Inst Res, Silver Spring, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1742-4690
J9 RETROVIROLOGY
JI Retrovirology
PY 2009
VL 6
AR P47
PG 1
WC Virology
SC Virology
GA 509KL
UT WOS:000271015300100
ER
PT J
AU Weaver, KL
Peachman, KK
Boonnak, K
Wieczorek, L
Matyas, GR
Asher, LM
Polonis, VR
Marovich, M
Alving, CR
Rao, M
AF Weaver, K. L.
Peachman, K. K.
Boonnak, K.
Wieczorek, L.
Matyas, G. R.
Asher, L. M.
Polonis, V. R.
Marovich, M.
Alving, C. R.
Rao, M.
TI Multispecific monoclonal antibodies bind to primary human macrophages
and induce the production of protective chemokines, MIP-1 alpha and
MIP-1 beta
SO RETROVIROLOGY
LA English
DT Meeting Abstract
C1 [Weaver, K. L.; Peachman, K. K.; Boonnak, K.; Wieczorek, L.; Asher, L. M.] US Mil HIV Res Program, Rockville, MD USA.
[Matyas, G. R.; Polonis, V. R.; Marovich, M.; Alving, C. R.; Rao, M.] Walter Reed Army Inst Res, Rockville, MD USA.
NR 0
TC 0
Z9 0
U1 1
U2 1
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1742-4690
J9 RETROVIROLOGY
JI Retrovirology
PY 2009
VL 6
AR P50
PG 1
WC Virology
SC Virology
GA 509KL
UT WOS:000271015300103
ER
PT S
AU Brush, ER
Adams, DE
Zwink, BR
Walsh, S
AF Brush, E. R.
Adams, D. E.
Zwink, B. R.
Walsh, S.
BE Thompson, DO
Chimenti, DE
TI PASSIVE HEALTH MONITORING COUPLED WITH FULL-FIELD ACTIVE INSPECTION OF
MULTI-LAYERED COMPOSITE ARMOR STRUCTURES
SO REVIEW OF PROGRESS IN QUANTITATIVE NONDESTRUCTIVE EVALUATION, VOLS 28A
AND 28B
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 35th Annual Review of Progress in Quantitative Nondestructive Evaluation
CY JUL 20-25, 2008
CL Univ Chicago, Chicago, IL
HO Univ Chicago
DE Structural Health Monitoring; Passive Damage Detection; Impact
Identification; Nonlinear Frequency Modulation
AB This paper presents the results of implementing vibration based damage detection techniques for in situ monitoring and offline nondestructive evaluation of composite armor materials. It is shown that exogenous impact forces can be passively detected, located, and quantified for specimens that were fabricated using woven S-2 glass, elastomer, and carbon fiber sandwich simulated multi-layered armor. Damaging impact energies are applied to test specimens and the passively measured frequency response of the armor is used to update the dynamic model of the specimen and subsequently estimate the level of damage incurred. The forced response of the material at the damaged region is investigated. It is shown that the material damping and stiffness in the damaged region exhibit nonlinearities. A laser Doppler vibrometer is also utilized to show that nonlinear frequency modulation techniques are useful for damage inspection.
C1 [Brush, E. R.; Adams, D. E.; Zwink, B. R.] Purdue Univ, Dept Mech Engn, W Lafayette, IN 47906 USA.
[Walsh, S.] US Army, Res Lab, APG, Aberdeen Proving Ground, MD USA.
RP Brush, ER (reprint author), Purdue Univ, Dept Mech Engn, W Lafayette, IN 47906 USA.
FU Army Research Office
FX The authors acknowledge the Army Research Office with Dr. Bruce
LaMattina as program manager for supporting this work.
NR 8
TC 0
Z9 0
U1 0
U2 0
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0629-2
J9 AIP CONF PROC
PY 2009
VL 1096
BP 1083
EP +
PG 2
WC Materials Science, Characterization & Testing; Physics, Applied
SC Materials Science; Physics
GA BKO01
UT WOS:000268740800137
ER
PT S
AU Brennan, RE
Green, WH
Sands, JM
Yu, JH
AF Brennan, R. E.
Green, W. H.
Sands, J. M.
Yu, J. H.
BE Thompson, DO
Chimenti, DE
TI NONDESTRUCTIVE EVALUATION (NDE) OF DAMAGED STRUCTURAL CERAMICS
SO REVIEW OF PROGRESS IN QUANTITATIVE NONDESTRUCTIVE EVALUATION, VOLS 28A
AND 28B
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 35th Annual Review of Progress in Quantitative Nondestructive Evaluation
CY JUL 20-25, 2008
CL Univ Chicago, Chicago, IL
HO Univ Chicago
DE Nondestructive Evaluation; Ultrasound; Digital Radiography; Imaging;
Impact Damage
AB A combination of destructive and nondestructive testing methods was utilized to evaluate the impact velocity and energy conditions that caused fracture in alumina structural ceramics. Drop tower testing was used for low velocity impact with a high mass indenter and fragment simulating projectile testing was used for high velocity impact with a low mass projectile. The damaged samples were nondestructively evaluated using digital radiography and ultrasound C-scan imaging. The bulk damage detected by these techniques was compared to surface damage observed by visual inspection.
C1 [Brennan, R. E.; Green, W. H.; Sands, J. M.; Yu, J. H.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Brennan, RE (reprint author), USA, Res Lab, 4600 Deer Creek Loop, Aberdeen Proving Ground, MD 21005 USA.
NR 7
TC 0
Z9 0
U1 0
U2 1
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0629-2
J9 AIP CONF PROC
PY 2009
VL 1096
BP 1091
EP 1098
PG 8
WC Materials Science, Characterization & Testing; Physics, Applied
SC Materials Science; Physics
GA BKO01
UT WOS:000268740800138
ER
PT S
AU Green, WH
Carter, RH
AF Green, W. H.
Carter, R. H.
BE Thompson, DO
Chimenti, DE
TI EVALUATION OF BALLISTIC DAMAGE IN AN ENCAPSULATED CERAMIC PANEL VIA
X-RAY COMPUTED TOMOGRAPHY
SO REVIEW OF PROGRESS IN QUANTITATIVE NONDESTRUCTIVE EVALUATION, VOLS 28A
AND 28B
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 35th Annual Review of Progress in Quantitative Nondestructive Evaluation
CY JUL 20-25, 2008
CL Univ Chicago, Chicago, IL
HO Univ Chicago
DE Computed Tomography; Nondestructive Evaluation/Testing (NDE/NDT);
Ceramics; Encapsulated; Damage
AB X-ray computed tomography (XCT) is an important non-destructive evaluation technique for revealing the spatial distribution of ballistically-induced damage in ceramics. The level of detection and resolution of damage depends on the size of the sample and the parameters of the XCT approach (e.g., focal spot size, magnification, etc.). Previous and ongoing work in this area includes assessment of ballistically induced damage in both individual ceramic targets and ceramic armor panels. Ballistic damage in an encapsulated ceramic armor panel with a metal backing has been scanned and extensively evaluated using XCT 2-D and 3-D analysis. The purpose of using XCT evaluation in this study was to better characterize and understand all of the detectable damage. This information can be used to correlate damage features and types with the physical processes of damage initiation and growth. XCT scans and analyses of damage in the panel will be shown and discussed. This will include virtual 3-D solid visualizations and some quantitative analysis of damage features.
C1 [Green, W. H.; Carter, R. H.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Green, WH (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
NR 2
TC 0
Z9 0
U1 2
U2 3
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0629-2
J9 AIP CONF PROC
PY 2009
VL 1096
BP 1099
EP 1106
PG 8
WC Materials Science, Characterization & Testing; Physics, Applied
SC Materials Science; Physics
GA BKO01
UT WOS:000268740800139
ER
PT S
AU Schmidt, KF
Little, JR
Ellingson, WA
Green, W
AF Schmidt, K. F., Jr.
Little, J. R., Jr.
Ellingson, W. A.
Green, W.
BE Thompson, DO
Chimenti, DE
TI A PORTABLE MICROWAVE INTERFERENCE SCANNING SYSTEM FOR NONDESTRUCTIVE
TESTING OF MULTI-LAYERED DIELECTRIC MATERIALS
SO REVIEW OF PROGRESS IN QUANTITATIVE NONDESTRUCTIVE EVALUATION, VOLS 28A
AND 28B
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 35th Annual Review of Progress in Quantitative Nondestructive Evaluation
CY JUL 20-25, 2008
CL Univ Chicago, Chicago, IL
HO Univ Chicago
DE Microwave; NDT; Ceramics; Composites
AB A portable, microwave interference scanning system, that can be used in situ, with one-sided, non-contact access, has been developed. It has demonstrated capability of damage detection on composite ceramic armor. Specimens used for validation included specially fabricated surrogates, and non-ballistic impact-damaged specimens. Microwave data results were corroborated with high resolution direct-digital x-ray imaging. Microwave interference scanning detects cracks, laminar features and material properties variations. This paper will present details of the system and discuss results obtained.
C1 [Schmidt, K. F., Jr.; Little, J. R., Jr.] Evisive Inc, Baton Rouge, LA USA.
[Ellingson, W. A.] Argonne Natl Lab, Argonne, IL USA.
[Green, W.] Army Res Lab, Aberdeen Proving Ground, MD USA.
RP Schmidt, KF (reprint author), Evisive Inc, Baton Rouge, LA USA.
FU US Army RDECOM ARL; US Army RDECOM TARDEC
FX This work is supported by the US Army RDECOM ARL and US Army RDECOM
TARDEC whose staffs insight and technical contribution is much
appreciated.
NR 8
TC 1
Z9 1
U1 0
U2 0
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0629-2
J9 AIP CONF PROC
PY 2009
VL 1096
BP 1107
EP +
PG 2
WC Materials Science, Characterization & Testing; Physics, Applied
SC Materials Science; Physics
GA BKO01
UT WOS:000268740800140
ER
PT S
AU Weiss, CA
Morefield, SW
Malone, PG
Koenigstein, ML
AF Weiss, Charles A., Jr.
Morefield, Sean W.
Malone, Philip G.
Koenigstein, Michael L.
BE LHostis, V
Gens, R
Galle, C
TI ROLE OF REACTIVE VITREOUS COATINGS IN REINFORCED CONCRETE IN NUCLEAR
PLANT CONSTRUCTION
SO RILEM WORKSHOP ON LONG-TERM PERFORMANCE OF CEMENTITIOUS BARRIERS AND
REINFORCED CONCRETE IN NUCLEAR POWER PLANTS AND WASTE MANAGEMENT
SE RILEM Proceedings
LA English
DT Proceedings Paper
CT RILEM Workshop on Long-Term Performance of Cementitious Barriers and
Reinforced Concrete in Nuclear Power Plants
CY MAR 30-APR 02, 2009
CL Cadarache, FRANCE
SP RILEM, European Federat Corrision, OECD, Nucl Energy Agcy
AB Reinforced concrete is the basic construction material in commercial nuclear power plants in the United States. The continued performance of these critical concrete structures is necessary to ensure the safety of plant personnel and the public in the surrounding area. Designs for complex concrete and steel structures such as containment domes, where steel frames and steel reinforcement have to bond securely to the surrounding concrete, encounter the problem making concrete adhere to steel. Concrete condition surveys conducted at nuclear power plants have shown that problems can develop at nuclear plants during operations that are typical of aging reinforced concrete structural members. Corrosion of the embedded steel is especially a problem where the concrete is exposed to moisture and oxygen can diffuse down to the concrete-steel interface and cause rust formation, expansion and cracking. The recent development of new engineered coatings for reinforcing steel that are based on using an alkali-resistant vitreous enamel to coat the steel and to fuse reactive calcium silicates and aluminates to the surface of the steel can be used to address both the bonding and the corrosion problem in reinforced concrete
C1 [Weiss, Charles A., Jr.] USA, Corps Engineers, Engineers Engineer Res & Dev Ctr, Vicksburg, MS USA.
RP Weiss, CA (reprint author), USA, Corps Engineers, Engineers Engineer Res & Dev Ctr, Vicksburg, MS USA.
NR 19
TC 0
Z9 0
U1 0
U2 2
PU R I L E M PUBLICATIONS
PI BAGNEUX
PA 157 RUE DES BLAINS, 92220 BAGNEUX, FRANCE
SN 1461-1147
BN 978-2-35158-072-1
J9 RILEM PROC
PY 2009
VL 64
BP 287
EP 294
PG 8
WC Construction & Building Technology; Engineering, Environmental;
Engineering, Civil; Materials Science, Multidisciplinary
SC Construction & Building Technology; Engineering; Materials Science
GA BVJ48
UT WOS:000291665400031
ER
PT S
AU Ashby, S
AF Ashby, S.
BE Brebbia, CA
TI Impacts of hydrology and hydropower on water quality in reservoir
tailwaters
SO RIVER BASIN MANAGEMENT V
SE WIT Transactions on Ecology and the Environment
LA English
DT Proceedings Paper
CT 5th International Conference on River Basin Management
CY 2009
CL MALTA
DE dams; reservoirs; tailwaters; water quality
AB Reservoirs alter riverine dynamics and can impact the water quality of the natural system. As demands for surface water Supplies and hydropower increase, Understanding the potential changes to riverine systems with construction and operation of darns is critical for decision-making in river basin management. This paper will utilize information from selected case studies to 1) overview the impacts of darns on river hydrology and water quality, and 2) provide tools used to mitigate impacts. For example, major changes to the natural hydrograph (e.g., dampening of storms, flow fluctuations associated with hydropower) will be summarized using examples of alterations to the downstream floodplain and channel hydrology and tools used in restoration actions. Changes in water quality in reservoir releases associated with retention and outlet works (e.g., temperature modifications, decreases in dissolved oxygen, and mobilization of nutrients and metals) will be reviewed. Case studies are used to describe downstream dissolved oxygen dynamics Such as sag and recovery and associated impacts on the kinetics of nutrients and metals. Transport, oxidation kinetics, and fate of dissolved nitrogen species (ammonia and nitrate) and metals (iron and manganese) are summarized using data from field and laboratory, studies Techniques such as selective withdrawal, aeration, oxygenation, and use of weirs to mitigate water quality impacts are presented. Lastly, effects throughout the river system associated with Multiple reservoirs (e.g. heat budgets and water supply) are discussed.
C1 USA, Engineer Res & Dev Ctr, Vicksburg, MS USA.
RP Ashby, S (reprint author), USA, Engineer Res & Dev Ctr, Vicksburg, MS USA.
NR 8
TC 0
Z9 0
U1 5
U2 18
PU WIT PRESS
PI SOUTHAMPTON
PA ASHURST LODGE, SOUTHAMPTON SO40 7AA, ASHURST, ENGLAND
SN 1743-3541
BN 978-1-84564-198-6
J9 WIT TRANS ECOL ENVIR
JI WIT Trans. Ecol. Environ.
PY 2009
VL 124
BP 55
EP 66
DI 10.2495/RM090061
PG 12
WC Ecology; Environmental Sciences
SC Environmental Sciences & Ecology
GA BMU65
UT WOS:000273610400006
ER
PT J
AU Blank, S
AF Blank, Stephen
TI Putin's Presidency and Russian History
SO RUSSIAN HISTORY-HISTOIRE RUSSE
LA English
DT Article
DE Hellie; service state; patrimonial autocracy; Muscovite; Russian
military; FSB; succession struggless
AB The regime crafted by Vladimir Putin and extended now with the election of Dmitry Medvedev in many ways represents a continuation of the Muscovite paradigm delineated by Professor Hellie in his earlier work. Indeed, we are witnessing the consolidation of a fourth version of the Muscovite service state and in the military a kind of serfdom still reigns. This continuity is not just a question of the autocracy of the Tsar but also of the tenuous situation regarding property rights which are not fully established. Furthermore, it is quite clear that government is still a service state where officials' income, power and status derive from the service they render the Tsar and their ability to provide the state's requirements in key industries. just as this elite may be considered a rent-seeking elite, so may the state be considered a rent-granting state that grants them rents in the form of office so that they can provide for themselves at the same time as they serve the Tsar.
C1 USA, War Coll, Strateg Studies Inst, Washington, DC USA.
RP Blank, S (reprint author), USA, War Coll, Strateg Studies Inst, Washington, DC USA.
EM stephen.blank@us.army.mil
NR 84
TC 1
Z9 1
U1 1
U2 5
PU BRILL ACADEMIC PUBLISHERS
PI LEIDEN
PA PLANTIJNSTRAAT 2, P O BOX 9000, 2300 PA LEIDEN, NETHERLANDS
SN 0094-288X
J9 RUSS HIST-HIST RUSS
JI Russ. Hist.-Hist. Russe
PY 2009
VL 36
IS 1
BP 88
EP 116
DI 10.1163/187633109X412311
PG 29
WC History
SC History
GA 490UW
UT WOS:000269533800006
ER
PT S
AU Ohs, RR
Schuster, JW
Fung, TY
AF Ohs, R. Ryan
Schuster, Joseph W.
Fung, Tat Y.
GP IEEE
TI Full Wave Simulation of Radiowave Propagation in Unattended Ground
Sensor Networks
SO RWS: 2009 IEEE RADIO AND WIRELESS SYMPOSIUM
SE IEEE Radio and Wireless Symposium
LA English
DT Proceedings Paper
CT IEEE Radio and Wireless Symposium
CY JAN 18-22, 2009
CL San Diego, CA
SP IEEE
DE Propagation; Simulation; Unattended ground sensors; FDTD
AB The moving window finite difference time domain (MWFDTD) method is used to analyze propagation between low to the ground antennas commonly used in wireless unattended ground sensor networks. The propagation path loss at 300 MHz is computed for several terrains exhibiting different degrees of roughness. From the pathloss results, the mean and standard deviation of the path loss distribution are determined as functions of distance from the transmitter. The mean loss is shown to be close to the loss over a flat ground for all roughness values, and the standard deviation is shown to increase with the roughness of the terrain.
C1 [Ohs, R. Ryan; Schuster, Joseph W.; Fung, Tat Y.] Remcom Inc, State Coll, PA 16801 USA.
[Ohs, R. Ryan; Schuster, Joseph W.; Fung, Tat Y.] US Army RDECOM, CERDEC, Ft Monmouth, NJ 07703 USA.
RP Ohs, RR (reprint author), Remcom Inc, State Coll, PA 16801 USA.
NR 3
TC 0
Z9 0
U1 0
U2 0
PU IEEE
PI NEW YORK
PA 345 E 47TH ST, NEW YORK, NY 10017 USA
SN 2164-2958
BN 978-1-4244-2698-0
J9 IEEE RADIO WIRELESS
PY 2009
BP 175
EP +
PG 2
WC Engineering, Electrical & Electronic; Telecommunications
SC Engineering; Telecommunications
GA BMY58
UT WOS:000273914400045
ER
PT J
AU Danko, JR
Gilliland, WR
Miller, RS
Decker, CF
AF Danko, Janine R.
Gilliland, William R.
Miller, R. Scott
Decker, Catherine F.
TI Disseminated Mycobacterium marinum infection in a patient with
rheumatoid arthritis receiving infliximab therapy
SO SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article
ID SKIN INFECTIONS
AB Tumor necrosis factor- inhibitors are important adjunctive therapies for rheumatologic diseases. These agents increase the risk for granulomatous disease. We present a case of a woman with severe rheumatoid arthritis on infliximab who developed multiple nodular skin lesions. Biopsies grew Mycobacterium marinum. New lesions developed through therapy, necessitating surgical debulking.
C1 [Danko, Janine R.] USN, Infect Dis Directorate, Viral Rickettsial Dis Dept, Med Res Ctr, Silver Spring, MD 20910 USA.
[Gilliland, William R.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
[Miller, R. Scott] Walter Reed Army Inst Res, Div Expt Therapeut, Silver Spring, MD USA.
[Decker, Catherine F.] Natl Naval Med Ctr, Div Infect Dis, Bethesda, MD USA.
RP Danko, JR (reprint author), USN, Infect Dis Directorate, Viral Rickettsial Dis Dept, Med Res Ctr, 503 Robert Grant Ave,Room 3N25, Silver Spring, MD 20910 USA.
EM janine.danko@med.navy.mil
NR 16
TC 15
Z9 15
U1 0
U2 0
PU INFORMA HEALTHCARE
PI LONDON
PA TELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLAND
SN 0036-5548
EI 1651-1980
J9 SCAND J INFECT DIS
JI Scand. J. Infect. Dis.
PY 2009
VL 41
IS 4
BP 252
EP 255
AR PII 909259105
DI 10.1080/00365540902774599
PG 4
WC Infectious Diseases
SC Infectious Diseases
GA 418GP
UT WOS:000264137000002
PM 19266397
ER
PT J
AU Fowler, JE
Resio, DT
AF Fowler, Jimmy E.
Resio, Donald T.
TI Cooperation and Innovation Lead to New Causeway System to Offload
Vessels
SO SEA TECHNOLOGY
LA English
DT Article
C1 [Fowler, Jimmy E.; Resio, Donald T.] USA, Coastal & Hydraul Lab, Engineer Res & Dev Ctr, Washington, DC USA.
RP Fowler, JE (reprint author), USA, Coastal & Hydraul Lab, Engineer Res & Dev Ctr, Washington, DC USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU COMPASS PUBLICATIONS, INC
PI ARLINGTON
PA 1501 WILSON BLVD., STE 1001, ARLINGTON, VA 22209-2403 USA
SN 0093-3651
J9 SEA TECHNOL
JI Sea Technol.
PD JAN
PY 2009
VL 50
IS 1
BP 16
EP +
PG 2
WC Engineering, Ocean
SC Engineering
GA 404KV
UT WOS:000263151400005
ER
PT S
AU Haynes, A
Gouma, PI
AF Haynes, Aisha
Gouma, Pelagia-Irene
BE Baraton, MI
TI POLYANILINE-BASED ENVIRONMENTAL GAS SENSORS
SO SENSORS FOR ENVIRONMENT, HEALTH AND SECURITY: ADVANCED MATERIALS AND
TECHNOLOGIES
SE NATO Science for Peace and Security Series C-Environmental Security
LA English
DT Proceedings Paper
CT NATO Advanced Study Institute on Sensors for Environment, Health and
Security - Advanced Materials and Technology
CY SEP 16-27, 2007
CL Vichy, FRANCE
SP NATO
DE conducting polymer; environmental sensor; polyaniline
ID CELLULOSE-ACETATE; THIN-FILM; ELECTRICAL-CONDUCTIVITY; SENSING
CHARACTERISTICS; POLYMER-FILM; COMPOSITES; SENSITIVITY; BLENDS; CO;
FABRICATION
AB Polyaniline (PANl) is an intrinsically conducting gas sensitive polymer. The responsive nature of PANl to environmental pollutants Such as NO2, CO, SO2 and other greenhouse gases, is highly dependent oil the processing techniques employed. The quality and stability of PANl based sensors have been evaluated by many researchers using various nano-manufacturing techniques to discern the effects oil electrical conductivity, selectivity, and sensitivity to various gas analytes. The focus of this work is to provide a brief review of these sensor technologies and the application of polyaniline for environmental monitoring applications.
C1 [Haynes, Aisha] US Army, Res Dev & Engn Command, Fuze Precis & Armanments Technol, Anal & Evaluat Technol, Picatinny Arsenal, NJ 07806 USA.
[Gouma, Pelagia-Irene] SUNY Stony Brook, Dept Mat Sci & Engn, Stony Brook, NY 11794 USA.
RP Haynes, A (reprint author), US Army, Res Dev & Engn Command, Fuze Precis & Armanments Technol, Anal & Evaluat Technol, Picatinny Arsenal, NJ 07806 USA.
EM aisha.s.haynes@us.army.mil
FU U.S. Army Research Development and Engineering Command, Benet
Laboratories
FX The authors would like to thank the U.S. Army Research Development and
Engineering Command, Benet Laboratories for supporting our current
efforts on developing a polyaniline-based chemical sensor.
NR 35
TC 4
Z9 4
U1 2
U2 5
PU SPRINGER
PI DORDRECHT
PA PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS
SN 1871-4668
BN 978-1-4020-9008-0
J9 NATO SCI PEACE SECUR
JI NATO Sci. Peace Secur. Ser. C- Environ. Secur.
PY 2009
BP 451
EP +
DI 10.1007/978-1-4020-9009-7_30
PG 4
WC Environmental Sciences; Remote Sensing
SC Environmental Sciences & Ecology; Remote Sensing
GA BIS94
UT WOS:000262475800030
ER
PT S
AU Johnsen, R
Golde, MF
Rosati, RE
Pappas, D
Skrzypkowski, MP
AF Johnsen, R.
Golde, M. F.
Rosati, R. E.
Pappas, D.
Skrzypkowski, M. P.
BE VanDerZande, WJ
TI Optical emissions from the dissociative recombination of N2H+, HCO+,
HOC+, and HNC+
SO SEVENTH INTERNATIONAL CONFERENCE ON DISSOCIATIVE RECOMBINATION: THEORY,
EXPERIMENTS AND APPLICATIONS (DR2007)
SE Journal of Physics Conference Series
LA English
DT Proceedings Paper
CT 7th International Conference on Dissociative Recombination: Theory,
Experiments and Applications
CY JUL 18-23, 2007
CL Radboud Univ Nijmegen, Ameland, NETHERLANDS
SP Fdn Fundamental Res Matter, Fdn PHYSICA, Netherlands Royal Acad Sci
HO Radboud Univ Nijmegen
ID ELECTRON-ION RECOMBINATION; VIBRATIONAL-EXCITATION; MERGED-BEAM; CO2+
IONS; PRODUCTS; HCN+; COEFFICIENTS; DEPENDENCE; YIELD; H-3+
AB We present recent flowing-afterglow measurements of branching fractions for electronically and vibrationally excited products arising from the dissociative recombination of N2H+, HCO+, HOC+, and HNC+ ions with thermal electrons. State-specific yields were derived by fitting the observed, spatially resolved emission band intensities to models that simulate all ion-chemical processes, recombination, diffusion, and gas mixing.
C1 [Johnsen, R.] Univ Pittsburgh, Dept Phys & Astron, Pittsburgh, PA 15260 USA.
[Golde, M. F.] Univ Pittsburgh, Dept Chem, Pittsburgh, PA 15260 USA.
[Rosati, R. E.] Smithsonian Astrophys Observ, Cambridge, MA 02138 USA.
[Pappas, D.] Army Res Lab, Aberdeen Proving Ground, MD USA.
[Skrzypkowski, M. P.] Prometheus Energy Co, Seattle, WA 98168 USA.
RP Johnsen, R (reprint author), Univ Pittsburgh, Dept Phys & Astron, Pittsburgh, PA 15260 USA.
EM rj@pitt.edu
FU NASA Planetary Atmospheres Program
FX This work was, in part, supported by the NASA Planetary Atmospheres
Program.
NR 31
TC 2
Z9 2
U1 0
U2 1
PU IOP PUBLISHING LTD
PI BRISTOL
PA DIRAC HOUSE, TEMPLE BACK, BRISTOL BS1 6BE, ENGLAND
SN 1742-6588
J9 J PHYS CONF SER
PY 2009
VL 192
AR UNSP 012009
DI 10.1088/1742-6596/192/1/012009
PG 9
WC Chemistry, Physical; Physics, Fluids & Plasmas
SC Chemistry; Physics
GA BTQ61
UT WOS:000287793300009
ER
PT J
AU Mace, JE
Schwacha, MG
White, CE
Park, MS
Chung, KK
Holcomb, JB
Wolf, SE
Wade, CE
AF Mace, J. E.
Schwacha, M. G.
White, C. E.
Park, M. S.
Chung, K. K.
Holcomb, J. B.
Wolf, S. E.
Wade, C. E.
TI THROMBOELASTOGRAPHY AND PLASMA CYTOKINE LEVELS AFTER BURN AND TRAUMA
SO SHOCK
LA English
DT Meeting Abstract
CT 32nd Annual Conference on Shock
CY JUN 06-09, 2009
CL San Antonio, TX
SP Shock Soc
C1 [Mace, J. E.; Schwacha, M. G.; White, C. E.; Park, M. S.; Chung, K. K.; Holcomb, J. B.; Wolf, S. E.; Wade, C. E.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA.
NR 0
TC 0
Z9 0
U1 1
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1073-2322
J9 SHOCK
JI Shock
PY 2009
VL 31
BP 37
EP 38
PG 2
WC Critical Care Medicine; Hematology; Surgery; Peripheral Vascular Disease
SC General & Internal Medicine; Hematology; Surgery; Cardiovascular System
& Cardiology
GA 463ND
UT WOS:000267438000113
ER
PT J
AU McGrath, S
Ryan, K
Wendleken, S
Rickards, C
Convertino, V
AF McGrath, S.
Ryan, K.
Wendleken, S.
Rickards, C.
Convertino, V.
TI PHOTOPLETHYSMOGRAM FEATURES TRACK REDUCTIONS IN CENTRAL BLOOD VOLUME IN
A HUMAN MODEL OF PRE-SHOCK HEMORRHAGE
SO SHOCK
LA English
DT Meeting Abstract
CT 32nd Annual Conference on Shock
CY JUN 06-09, 2009
CL San Antonio, TX
SP Shock Soc
C1 [McGrath, S.; Ryan, K.; Wendleken, S.; Rickards, C.; Convertino, V.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1073-2322
J9 SHOCK
JI Shock
PY 2009
VL 31
BP 43
EP 44
PG 2
WC Critical Care Medicine; Hematology; Surgery; Peripheral Vascular Disease
SC General & Internal Medicine; Hematology; Surgery; Cardiovascular System
& Cardiology
GA 463ND
UT WOS:000267438000130
ER
PT J
AU Rickards, C
Ryan, K
Convertino, V
AF Rickards, C.
Ryan, K.
Convertino, V.
TI LIMITATIONS OF HEART PERIOD VARIABILITY FOR MONITORING INDIVIDUAL TRAUMA
PATIENTS IN THE PRE-HOSPITAL SETTING
SO SHOCK
LA English
DT Meeting Abstract
CT 32nd Annual Conference on Shock
CY JUN 06-09, 2009
CL San Antonio, TX
SP Shock Soc
C1 [Rickards, C.; Ryan, K.; Convertino, V.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1073-2322
J9 SHOCK
JI Shock
PY 2009
VL 31
BP 44
EP 45
PG 2
WC Critical Care Medicine; Hematology; Surgery; Peripheral Vascular Disease
SC General & Internal Medicine; Hematology; Surgery; Cardiovascular System
& Cardiology
GA 463ND
UT WOS:000267438000133
ER
PT J
AU Ryan, K
Rickards, C
Ludwig, D
Convertino, V
AF Ryan, K.
Rickards, C.
Ludwig, D.
Convertino, V.
TI TRACKING CENTRAL HYPOVOLEMIA WITH HEART PERIOD VARIABILITY (HPV) IN
HUMANS: IMPLICATIONS FOR PATIENT MONITORING
SO SHOCK
LA English
DT Meeting Abstract
CT 32nd Annual Conference on Shock
CY JUN 06-09, 2009
CL San Antonio, TX
SP Shock Soc
C1 [Ryan, K.; Rickards, C.; Ludwig, D.; Convertino, V.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1073-2322
J9 SHOCK
JI Shock
PY 2009
VL 31
BP 44
EP 44
PG 1
WC Critical Care Medicine; Hematology; Surgery; Peripheral Vascular Disease
SC General & Internal Medicine; Hematology; Surgery; Cardiovascular System
& Cardiology
GA 463ND
UT WOS:000267438000132
ER
PT J
AU Darlington, D
Scherer, M
Miranda, N
Kheirabadi, B
Dubick, M
AF Darlington, D.
Scherer, M.
Miranda, N.
Kheirabadi, B.
Dubick, M.
TI HYPOCOAGULATION CAUSED BY METABOLIC RESPIRATORY-INDUCED ACIDOSIS IS NOT
REVERSED BY PH CORRECTION
SO SHOCK
LA English
DT Meeting Abstract
CT 32nd Annual Conference on Shock
CY JUN 06-09, 2009
CL San Antonio, TX
SP Shock Soc
C1 [Darlington, D.; Scherer, M.; Miranda, N.; Kheirabadi, B.; Dubick, M.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1073-2322
J9 SHOCK
JI Shock
PY 2009
VL 31
BP 45
EP 46
PG 2
WC Critical Care Medicine; Hematology; Surgery; Peripheral Vascular Disease
SC General & Internal Medicine; Hematology; Surgery; Cardiovascular System
& Cardiology
GA 463ND
UT WOS:000267438000136
ER
PT J
AU Sethuraman, G
Ryan, K
Rickards, C
Convertino, V
AF Sethuraman, G.
Ryan, K.
Rickards, C.
Convertino, V.
TI ECTOPIC BEATS IN HEALTHY HUMANS AND TRAUMA PATIENTS: IMPLICATIONS FOR
USE OF HEART PERIOD VARIABILITY INDICES IN MEDICAL MONITORING
SO SHOCK
LA English
DT Meeting Abstract
CT 32nd Annual Conference on Shock
CY JUN 06-09, 2009
CL San Antonio, TX
SP Shock Soc
C1 [Sethuraman, G.; Ryan, K.; Rickards, C.; Convertino, V.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1073-2322
J9 SHOCK
JI Shock
PY 2009
VL 31
BP 45
EP 45
PG 1
WC Critical Care Medicine; Hematology; Surgery; Peripheral Vascular Disease
SC General & Internal Medicine; Hematology; Surgery; Cardiovascular System
& Cardiology
GA 463ND
UT WOS:000267438000134
ER
PT J
AU Navarro, L
Lima, R
Kinsky, M
Voigt, R
Sondeen, J
Dubick, M
Salinas, J
Kramer, G
AF Navarro, L.
Lima, R.
Kinsky, M.
Voigt, R.
Sondeen, J.
Dubick, M.
Salinas, J.
Kramer, G.
TI VITAL SIGNS MONITORING TO PREDICT BLOOD LOSS DURING ACUTE HEMORRHAGE IN
ANESTHETIZED SWINE
SO SHOCK
LA English
DT Meeting Abstract
CT 32nd Annual Conference on Shock
CY JUN 06-09, 2009
CL San Antonio, TX
SP Shock Soc
C1 UTMB, Galveston, TX 77555 USA.
USA, Inst Surg Res, San Antonio, TX 78234 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1073-2322
J9 SHOCK
JI Shock
PY 2009
VL 31
BP 47
EP 48
PG 2
WC Critical Care Medicine; Hematology; Surgery; Peripheral Vascular Disease
SC General & Internal Medicine; Hematology; Surgery; Cardiovascular System
& Cardiology
GA 463ND
UT WOS:000267438000141
ER
PT J
AU Stern, S
Rice, J
Philbin, N
McGwin, G
Arnaud, F
Johnson, T
Flournoy, WS
Ahlers, S
Pearce, LB
McCarron, R
Freilich, D
AF Stern, Susan
Rice, Jennifer
Philbin, Nora
McGwin, Gerald
Arnaud, Francoise
Johnson, Todd
Flournoy, W. Shannon
Ahlers, Stephen
Pearce, L. Bruce
McCarron, Richard
Freilich, Daniel
TI RESUSCITATION WITH THE HEMOGLOBIN-BASED OXYGEN CARRIER, HBOC-201, IN A
SWINE MODEL OF SEVERE UNCONTROLLED HEMORRHAGE AND TRAUMATIC BRAIN INJURY
SO SHOCK
LA English
DT Article
DE Hemoglobin-based oxygen carrier; HBOC-201; hemorrhagic shock; traumatic
brain injury; resuscitation
ID BOVINE POLYMERIZED HEMOGLOBIN; CEREBRAL-BLOOD-FLOW; HYPERTONIC SALINE
DEXTRAN; LACTATED RINGERS SOLUTION; LOW-VOLUME RESUSCITATION;
CROSS-LINKED HEMOGLOBIN; CLOSED-HEAD TRAUMA; INTRACRANIAL-PRESSURE;
INTRAVASCULAR MACROPHAGES; HYPOTENSIVE RESUSCITATION
AB The purpose of this investigation was to compare the effects of initial resuscitation with HBOC-201 to that of lactated Ringer (LR) solution in the setting of uncontrolled hemorrhage and traumatic brain injury (TBI). Anesthetized immature swine underwent fluid-percussion TBI and liver laceration. During a 75-min "prehospital phase," the animals were resuscitated with HBOC-201, LR solution, or nothing (NON). Upon "hospital arrival," the animals were provided blood and 0.9% NaCl as needed, and the liver injury was repaired. Surviving animals were killed 6 h after injury. Brain tissue was processed for blood flow, and gross, light microscopic, and immunohistochemical analyses. Mean TBI force (2.6 +/- 0.6 atm) and blood loss (64.4 +/- 3.4 mL/kg) were similar between groups. Six-hour survival was significantly greater in HBOC-201 (8 of 13 [62%]) versus LR solution (1 of 11 [9%]) and NON (11 of 8 [3%]) animals (P < 0.02). Mean arterial pressures, cardiac indices, cerebral perfusion pressures, and brain tissue oxygen tension were significantly greater, and lactate and base deficit were lower in HBOC-201 as compared with LR solution animals. Blood transfusion requirements were reduced in HBOC-201 (3.6 +/- 0.6 mL/kg per survival hour) as compared to 7.1 +/- 1.2 mL/kg per survival hour. Severity of subarachnoid and intraparenchymal hemorrhages was statistically greater in LR solution-treated animals, but these differences were not likely to be clinically significant. There were no differences in glial fibrillary acidic protein and microtubule-associated protein 2. In this model of combined uncontrolled hemorrhage and TBI, initial resuscitation with HBOC-201 resulted in significant improvements in survival and systemic and cerebrovascular physiological parameters, as well as a reduction in transfusion requirements.
C1 [Stern, Susan] Univ Michigan, Dept Emergency Med, Ann Arbor, MI 48109 USA.
[Rice, Jennifer; Philbin, Nora; Arnaud, Francoise; Johnson, Todd; Ahlers, Stephen; McCarron, Richard; Freilich, Daniel] Naval Med Res Ctr, Silver Spring, MD USA.
[McGwin, Gerald] Univ Alabama, Birmingham, AL USA.
[Flournoy, W. Shannon] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Pearce, L. Bruce] Biopure Corp, Cambridge, MA USA.
RP Stern, S (reprint author), Univ Michigan, Dept Emergency Med, TC B1 354,Box 0303,1500 E Med Ctr Dr, Ann Arbor, MI 48109 USA.
EM suestern@umich.edu
FU US Government (Office of Naval Research) [604771N.9595.001.A0315]
FX D.F. is a military service member (or employee of the US government).
This work was prepared as part of my official duties. Title 17 U.S.C 105
provides that "Copyright protection under this title is not available
for any work of the United States Government." Title 17 U.S.C 101
defines a US Government work as a work prepared by a military service
member or employee of the US Government as part of that person's
official duties.
NR 91
TC 29
Z9 30
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1073-2322
J9 SHOCK
JI Shock
PD JAN
PY 2009
VL 31
IS 1
BP 64
EP 79
DI 10.1097/SHK.0b013e3181778dc3
PG 16
WC Critical Care Medicine; Hematology; Surgery; Peripheral Vascular Disease
SC General & Internal Medicine; Hematology; Surgery; Cardiovascular System
& Cardiology
GA 385LO
UT WOS:000261815900010
PM 18497706
ER
PT J
AU Cho, SD
Holcomb, JB
Tieu, BH
Englehart, MS
Morris, MS
Karahan, ZA
Underwood, SA
Muller, PJ
Prince, MD
Medina, L
Sondeen, J
Shults, C
Duggan, M
Tabbara, M
Alam, HB
Schreiber, MA
AF Cho, S. David
Holcomb, John B.
Tieu, Brandon H.
Englehart, Michael S.
Morris, Melanie S.
Karahan, Z. Ayhan
Underwood, Samantha A.
Muller, Patrick J.
Prince, M. Dale
Medina, Leticia
Sondeen, Jill
Shults, Christian
Duggan, Michael
Tabbara, Malek
Alam, Hasan B.
Schreiber, Martin A.
TI REPRODUCIBILITY OF AN ANIMAL MODEL SIMULATING COMPLEX COMBAT-RELATED
INJURY IN A MULTIPLE-INSTITUTION FORMAT
SO SHOCK
LA English
DT Article
DE Resuscitation; trauma; preclinical trial; shock; femur fracture;
multicenter; swine; coagulopathy
ID UNCONTROLLED HEMORRHAGIC-SHOCK; FRESH-FROZEN PLASMA; PROTHROMBIN TIME;
LACTATED RINGERS; NORMAL SALINE; EARLY COAGULOPATHY; ACUTE TRAUMA; SWINE
MODEL; BLOOD-LOSS; RESUSCITATION
AB We developed a complex combat-relevant model of abdominal and extremity trauma, hemorrhagic shock, hypothermia, and acidosis. We then simulated injury, preoperative, and operative phases. We hypothesized that this model is reproducible and useful for randomized multicenter preclinical trials. Yorkshire swine were anesthetized, intubated, and instrumented. They then underwent femur fracture, 60% total blood volume hemorrhage, a 30-min shock period, induced hypothermia to 33 degrees C, and hemorrhage volume replacement with 3:1 isotonic sodium chloride solution (NS) at each of three centers. Hemodynamic parameters were measured continuously. Thromboelastography, arterial blood gas, and laboratory values were collected at baseline, after the shock period, and after NS replacement. Thirty-seven animals were used for model development. Eight (21%) died before completion of the study period. Twenty-nine survivors were included in the analysis. MAP (+/- SEM) after the shock period was 32 +/- 2 mmHg and was similar between centers (P = 0.4). Mean pH, base deficit, and lactate levels were 7.29 +/- 0.02, 8.20 +/- 0.65 mmol/L, and 5.29 +/- 0.44 mmol/L, respectively, after NS replacement. These were similar between centers (P > 0.05). Prothrombin time values increased significantly over time at all centers, reflecting a progressive coagulopathy (P < 0.02). Thromboelastography maximum amplitude values were similar among centers (P > 0.05) and demonstrated progressively weakened platelet interaction over time (P < 0.03). Hematocrit was similar after controlled hemorrhage (P = 0.15) and dilution (P = 0.9). The pH, lactate, base deficit, and coagulation tests reflect a severely injured state. A complex porcine model of polytrauma and shock can be used for multi-institutional study with excellent reproducibility. A consistent severe injury profile was achieved, after which experimental interventions can be applied. This is the first report of a reproducible multicenter trauma and resuscitation-related animal model.
C1 [Cho, S. David; Tieu, Brandon H.; Englehart, Michael S.; Morris, Melanie S.; Karahan, Z. Ayhan; Underwood, Samantha A.; Muller, Patrick J.; Schreiber, Martin A.] Oregon Hlth & Sci Univ, Div Trauma & Crit Care, Portland, OR 97239 USA.
[Holcomb, John B.; Prince, M. Dale; Medina, Leticia; Sondeen, Jill] USA, Inst Surg Res, Houston, TX USA.
[Shults, Christian; Duggan, Michael; Tabbara, Malek; Alam, Hasan B.] Massachusetts Gen Hosp, Div Trauma Emergency Surg & Surg Crit Care, Boston, MA 02114 USA.
RP Cho, SD (reprint author), Oregon Hlth & Sci Univ, Div Trauma & Crit Care, 3181 SW Sam Jackson Pk Rd,L611, Portland, OR 97239 USA.
EM chos@ohsu.edu
OI Tabbara, Malek/0000-0003-1046-7803
NR 42
TC 40
Z9 41
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1073-2322
J9 SHOCK
JI Shock
PD JAN
PY 2009
VL 31
IS 1
BP 87
EP 96
DI 10.1097/SHK.0b013e3181777ffb
PG 10
WC Critical Care Medicine; Hematology; Surgery; Peripheral Vascular Disease
SC General & Internal Medicine; Hematology; Surgery; Cardiovascular System
& Cardiology
GA 385LO
UT WOS:000261815900012
PM 18497710
ER
PT J
AU Batchinsky, A
Black, I
Necsoiu, C
Jones, J
Cancio, L
AF Batchinsky, A.
Black, I.
Necsoiu, C.
Jones, J.
Cancio, L.
TI HEART RATE COMPLEXITY IS DECREASED DURING APNEA AND RESPIRATORY ACIDOSIS
SO SHOCK
LA English
DT Meeting Abstract
CT 32nd Annual Conference on Shock
CY JUN 06-09, 2009
CL San Antonio, TX
SP Shock Soc
C1 [Batchinsky, A.; Black, I.; Necsoiu, C.; Jones, J.; Cancio, L.] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1073-2322
J9 SHOCK
JI Shock
PY 2009
VL 31
BP 89
EP 89
PG 1
WC Critical Care Medicine; Hematology; Surgery; Peripheral Vascular Disease
SC General & Internal Medicine; Hematology; Surgery; Cardiovascular System
& Cardiology
GA 463ND
UT WOS:000267438000258
ER
PT J
AU Spinella, P
Holcomb, J
Wade, C
Blackbourne, L
AF Spinella, P.
Holcomb, J.
Wade, C.
Blackbourne, L.
TI PREDICTORS OF MORTALITY FOR PENETRATING INJURIES EXCLUDING ISOLATED HEAD
INJURY
SO SHOCK
LA English
DT Meeting Abstract
CT 32nd Annual Conference on Shock
CY JUN 06-09, 2009
CL San Antonio, TX
SP Shock Soc
C1 [Spinella, P.; Holcomb, J.; Wade, C.; Blackbourne, L.] USA, Inst Surg Res, San Antonio, TX 78234 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1073-2322
J9 SHOCK
JI Shock
PY 2009
VL 31
BP 91
EP 92
PG 2
WC Critical Care Medicine; Hematology; Surgery; Peripheral Vascular Disease
SC General & Internal Medicine; Hematology; Surgery; Cardiovascular System
& Cardiology
GA 463ND
UT WOS:000267438000264
ER
PT J
AU Stites, N
White, J
Adams, DE
Triplett, M
AF Stites, Nick
White, Jonathan
Adams, Douglas E.
Triplett, Matt
TI Minimal-sensing, passive force identification techniques for a composite
structural missile component
SO SHOCK AND VIBRATION
LA English
DT Article
DE Passive; active; load; force; damage; identification; estimation;
quantification; frequency response
ID IMPACT FORCE; DOMAIN; LOADS
AB Structural health monitoring systems are often limited to the use of one sensor due to cost, complexity, and weight restrictions. Therefore, there is a need to develop load and damage identification techniques that utilize only one sensor. Two passive force estimation techniques are investigated in this work. The techniques focus on either the shape or the amplitude of the magnitude of the applied force in the frequency domain. Both techniques iteratively reduce an underdetermined set of equations of motion into many overdetermined systems of equations to solve for the force estimates. The techniques are shown to locate and quantify impulsive impacts with over 97% accuracy and non-impulsive impacts with at least 87% accuracy. A filament-wound rocket motor casing is used as a test structure. Impacts not acting at a specific input degree of freedom are also accurately located depending on the distance away from the modeled input degrees of freedom, and damaging impact forces are quantified by making assumptions about the impulsive nature of the applied force.
C1 [Stites, Nick; White, Jonathan; Adams, Douglas E.] Purdue Univ, Ray W Herrick Labs, W Lafayette, IN 47906 USA.
[Triplett, Matt] USA, RDECOM, AMSRD AMR PS AM, Redstone Arsenal, AL 35898 USA.
RP Adams, DE (reprint author), Purdue Univ, Ray W Herrick Labs, 140 S Intramural Dr, W Lafayette, IN 47906 USA.
EM deadams@purdue.edu
NR 20
TC 1
Z9 1
U1 1
U2 6
PU IOS PRESS
PI AMSTERDAM
PA NIEUWE HEMWEG 6B, 1013 BG AMSTERDAM, NETHERLANDS
SN 1070-9622
J9 SHOCK VIB
JI Shock Vib.
PY 2009
VL 16
IS 2
BP 117
EP 142
DI 10.3233/SAV-2009-0456
PG 26
WC Acoustics; Engineering, Mechanical; Mechanics
SC Acoustics; Engineering; Mechanics
GA 421SC
UT WOS:000264377600001
ER
PT J
AU Su, ZB
Peng, W
Zhang, ZY
Gogos, G
Skaggs, R
Cheeseman, B
Yen, CF
AF Su, Zhenbi
Peng, Wen
Zhang, Zhaoyan
Gogos, George
Skaggs, Reed
Cheeseman, Bryan
Yen, Chian Fong
TI Experimental investigation of a novel blast wave mitigation device
SO SHOCK AND VIBRATION
LA English
DT Article
DE Shock wave; mitigation device; Hopkinson bar
ID ATTENUATION; EXPLOSIVES; PROTECTION; AIRBLAST; WALLS
AB A novel blast wave mitigation device was investigated experimentally in this paper. The device consists of a piston-cylinder assembly. A shock wave is induced within the cylinder when a blast wave impacts on the piston. The shock wave propagates inside the device and is reflected repeatedly. The shock wave propagation process inside the device lengthens the duration of the force on the base of the device to several orders of magnitude of the duration of the blast wave, while it decreases the maximum pressure over an order of magnitude. Two types of experiments were carried out to study the blast wave mitigation device. The first type of experiments was done with honeycomb structures protected by the blast wave mitigation device. Experimental results show that the device can adequately protect the honeycomb structure. A second type of experiments was done using a Hopkinson bar to measure the pressure transmitted through the blast wave mitigation device. The experimental results agree well with results from a theoretical model.
C1 [Su, Zhenbi; Peng, Wen; Zhang, Zhaoyan; Gogos, George] Univ Nebraska, Dept Mech Engn, Lincoln, NE 68588 USA.
[Skaggs, Reed; Cheeseman, Bryan; Yen, Chian Fong] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Zhang, ZY (reprint author), Univ Nebraska, Dept Mech Engn, Lincoln, NE 68588 USA.
EM zzhang5@unl.edu
FU Army Research Office [W911NF-04-2-0011]
FX Financial support for this study by Army Research Office Contract
W911NF-04-2-0011 is gratefully acknowledged.
NR 15
TC 3
Z9 3
U1 2
U2 9
PU IOS PRESS
PI AMSTERDAM
PA NIEUWE HEMWEG 6B, 1013 BG AMSTERDAM, NETHERLANDS
SN 1070-9622
J9 SHOCK VIB
JI Shock Vib.
PY 2009
VL 16
IS 6
BP 543
EP 553
DI 10.3233/SAV-2009-0487
PG 11
WC Acoustics; Engineering, Mechanical; Mechanics
SC Acoustics; Engineering; Mechanics
GA 533AI
UT WOS:000272793600001
ER
PT S
AU Cheeseman, BA
Dandekar, DP
AF Cheeseman, B. A.
Dandekar, D. P.
BE Elert, ML
Buttler, WT
Furnish, MD
Anderson, WW
Proud, WG
TI NUMERICAL SIMULATIONS OF LATERAL STRESS PROFILES
SO SHOCK COMPRESSION OF CONDENSED MATTER - 2009, PTS 1 AND 2
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 16th Conference of the American-Physical-Society-Topical-Group on Shock
Compression of Condensed Matter
CY JUN 28-JUL 03, 2009
CL Nashville, TN
SP Amer Phys Soc, Topical Grp
DE Numerical simulations; coupled eulerian-lagrangian; lateral stress
profiles; silicon carbide
ID SILICON-CARBIDE; PIEZORESISTANCE GAUGES; COMPRESSION; STRENGTH
AB A series of numerical simulations have been conducted to provide insight into the observed lateral stress profiles in shocked silicon carbide reported in [1]. Utilizing a coupled Euler-Lagrange simulation approach, the thin epoxy layer has been included in the model. When utilizing the Johnson-Holmquist ceramic model with the constants published in [2], the two-step structure of the lateral stress measurement has been successfully reproduced. The influence of the epoxy layer on the development of the stress profile will be discussed. Additional simulations of specimens having buffer plates will be performed to simulate the lateral stress profile.
C1 [Cheeseman, B. A.; Dandekar, D. P.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Cheeseman, BA (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
NR 10
TC 0
Z9 0
U1 0
U2 0
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0732-9
J9 AIP CONF PROC
PY 2009
VL 1195
BP 83
EP 86
PG 4
WC Physics, Condensed Matter
SC Physics
GA BOG48
UT WOS:000276574100017
ER
PT S
AU Grinfeld, MA
AF Grinfeld, M. A.
BE Elert, ML
Buttler, WT
Furnish, MD
Anderson, WW
Proud, WG
TI VOIDS AS TRIGGERS OF HOT SPOTS IN SOLIDS
SO SHOCK COMPRESSION OF CONDENSED MATTER - 2009, PTS 1 AND 2
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 16th Conference of the American-Physical-Society-Topical-Group on Shock
Compression of Condensed Matter
CY JUN 28-JUL 03, 2009
CL Nashville, TN
SP Amer Phys Soc, Topical Grp
DE hot spots; ignition; solids; insensitive munition
AB A characteristic feature of solid agglomerates as compared with liquid energetic materials is the possibility of localizing dissipation and adiabatic heating near inhomogeneities, especially, at crack tips, sharp corners, etc. Inhomogeneities of macroscopic size can be modeled by using a continuum approach which studies the reversible and irreversible effects responsible for generating hot spots. We explore the appearance of stress driven hot spots in a systematic quantitative way. A closed-form analytical solution is obtained for ellipsoidal inclusions in isotropic media. Our model shows that the rate of thermomechanical dissipation of work essentially increases around penny-shaped elliptical voids.
C1 USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Grinfeld, MA (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
NR 7
TC 1
Z9 1
U1 0
U2 2
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0732-9
J9 AIP CONF PROC
PY 2009
VL 1195
BP 201
EP 204
PG 4
WC Physics, Condensed Matter
SC Physics
GA BOG48
UT WOS:000276574100046
ER
PT S
AU Baer, MR
Root, S
Dattelbaum, D
Hooks, DE
Gustavsen, RL
Orler, B
Pierce, T
Garcia, F
Vandersall, K
De Fisher, S
Travers, B
AF Baer, M. R.
Root, S.
Dattelbaum, D.
Hooks, D. E.
Gustavsen, R. L.
Orler, B.
Pierce, T.
Garcia, F.
Vandersall, K.
De Fisher, S.
Travers, B.
BE Elert, ML
Buttler, WT
Furnish, MD
Anderson, WW
Proud, WG
TI SHOCKLESS COMPRESSION STUDIES OF HMX-BASED EXPLOSIVES
SO SHOCK COMPRESSION OF CONDENSED MATTER - 2009, PTS 1 AND 2
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 16th Conference of the American-Physical-Society-Topical-Group on Shock
Compression of Condensed Matter
CY JUN 28-JUL 03, 2009
CL Nashville, TN
SP Amer Phys Soc, Topical Grp
DE Isentropic compression; Z accelerator; polymer binders; energetic
composites; CTH modeling
AB Several HMX-based explosive samples were subjected to shockless compression using Sandia's Z magnetic compression accelerator. A multi-panel ICE configuration containing various thicknesses of energetic composites PBX9501, PBXN9, LX-10 was subjected to ramp loading up to 320 Kbar over 500 ns. A Velocity Interferometer System for Any Reflector (VISAR) was used to measure transmitted wave profile data of particle velocity and forward and backward procedures were used with an optimization method to determine appropriate EOS data.
C1 [Baer, M. R.; Root, S.] Sandia Natl Labs, POB 5800, Albuquerque, NM 87185 USA.
[Dattelbaum, D.; Hooks, D. E.; Gustavsen, R. L.; Orler, B.; Pierce, T.] Los Alamos Natl Lab, Los Alamos, NM 87545 USA.
[Garcia, F.; Vandersall, K.] Lawrence Livermore Natl Lab, Livermore, CA 94550 USA.
[De Fisher, S.; Travers, B.] US Army ARDEC, Picatinny Arsenal, NJ 07806 USA.
RP Baer, MR (reprint author), Sandia Natl Labs, POB 5800, Albuquerque, NM 87185 USA.
FU US Dept of Energy's NNSA [DE-AC04-94AL85000]; DoD/DOE MOU IMP program
FX The authors thank M. Hobbs for his help with the optimization used in
the modeling and the assistance of the personnel at the Sandia Z
facility. Sandia is a multiprogram laboratory operated by Sandia
Corporation, a Lockheed Martin Company, for the US Dept of Energy's NNSA
under contract DE-AC04-94AL85000 and funding for this work was supported
by the DoD/DOE MOU IMP program.
NR 7
TC 2
Z9 2
U1 0
U2 3
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0732-9
J9 AIP CONF PROC
PY 2009
VL 1195
BP 699
EP +
PG 2
WC Physics, Condensed Matter
SC Physics
GA BOG48
UT WOS:000276574100165
ER
PT S
AU Raftenberg, MN
Scheidler, MJ
AF Raftenberg, M. N.
Scheidler, M. J.
BE Elert, ML
Buttler, WT
Furnish, MD
Anderson, WW
Proud, WG
TI GAP FORMATIONS IN SIMULATIONS OF SHPB TESTS ON ELASTIC MATERIALS SOFT IN
SHEAR
SO SHOCK COMPRESSION OF CONDENSED MATTER - 2009, PTS 1 AND 2
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 16th Conference of the American-Physical-Society-Topical-Group on Shock
Compression of Condensed Matter
CY JUN 28-JUL 03, 2009
CL Nashville, TN
SP Amer Phys Soc, Topical Grp
DE split Hopkinson pressure bar; ballistic gelatin; LS-DYNA; interfacial
gaps
AB The LS-DYNA code was applied to split Hopkinson pressure bar tests on a material at least two orders of magnitude stiffer in dilatation than in shear. Two constitutive models were applied, linear elasticity and a compressible form of Mooney-Rivlin elasticity. The latter was fitted to data from ballistic gelatin. The incident and transmission bars were aluminum. The nominal strain rate was 2500/s. Gaps appeared at the interfaces between the specimen and both bars. Unloading of the specimen and bars accompanied these gaps. The input-velocity rise time was varied to observe pulse shaping effects. Mesh sensitivity and contact-parameter sensitivity studies were performed.
C1 [Raftenberg, M. N.; Scheidler, M. J.] USA, Res Lab, Impact Phys Branch, Aberdeen Proving Ground, MD 21005 USA.
RP Raftenberg, MN (reprint author), USA, Res Lab, Impact Phys Branch, Aberdeen Proving Ground, MD 21005 USA.
NR 3
TC 0
Z9 0
U1 0
U2 0
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0732-9
J9 AIP CONF PROC
PY 2009
VL 1195
BP 715
EP 718
PG 4
WC Physics, Condensed Matter
SC Physics
GA BOG48
UT WOS:000276574100169
ER
PT S
AU Florando, JN
Jiao, T
Grunschel, SE
Clifton, RJ
Lassila, DH
Ferranti, L
Becker, RC
Minich, RW
Bazan, G
AF Florando, J. N.
Jiao, T.
Grunschel, S. E.
Clifton, R. J.
Lassila, D. H.
Ferranti, L.
Becker, R. C.
Minich, R. W.
Bazan, G.
BE Elert, ML
Buttler, WT
Furnish, MD
Anderson, WW
Proud, WG
TI HIGH RATE PLASTICITY UNDER PRESSURE USING A WINDOWED PRESSURE-SHEAR
IMPACT EXPERIMENT
SO SHOCK COMPRESSION OF CONDENSED MATTER - 2009, PTS 1 AND 2
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 16th Conference of the American-Physical-Society-Topical-Group on Shock
Compression of Condensed Matter
CY JUN 28-JUL 03, 2009
CL Nashville, TN
SP Amer Phys Soc, Topical Grp
DE transverse waves; vanadium; strength
ID COMPRESSION; ALUMINUM
AB An experimental technique has been developed to study the strength of materials under conditions of moderate pressures and high shear strain rates. The technique is similar to the traditional pressure-shear plate-impact experiments except that window interferometry is used to measure both the normal and transverse particle velocities at a sample-window interface. Experimental and simulation results on vanadium samples backed with a sapphire window show the utility of the technique to measure the flow strength under dynamic loading conditions. The results show that the strength of the vanadium is approximately 600 MPa at a pressure of 4.5 GPa and a plastic strain of 1.7%.
C1 [Florando, J. N.; Lassila, D. H.; Ferranti, L.; Becker, R. C.; Minich, R. W.; Bazan, G.] Lawrence Livermore Natl Lab, 7000 E Ave, Livermore, CA 94551 USA.
[Jiao, T.; Grunschel, S. E.; Clifton, R. J.] Brown Univ, Div Engn, Providence, RI 02912 USA.
[Grunschel, S. E.] US Army Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Florando, JN (reprint author), Lawrence Livermore Natl Lab, 7000 E Ave, Livermore, CA 94551 USA.
RI Becker, Richard/I-1196-2013
FU LLNL Laboratory Directed Research and Development; WCI "Dynamics of
Metals" program
FX Funding was provided by the LLNL Laboratory Directed Research and
Development and the WCI "Dynamics of Metals" programs. The authors would
like to thank Hoang Nguyen and Tom Carlson for lithography and etching
of the gratings, Johann Lotscher and Philip Ramsey for the vanadium
coatings, and Tien Shen for discussions regarding application of the
Steinberg-Lund model to vanadium.
NR 12
TC 1
Z9 1
U1 0
U2 0
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0732-9
J9 AIP CONF PROC
PY 2009
VL 1195
BP 723
EP +
PG 2
WC Physics, Condensed Matter
SC Physics
GA BOG48
UT WOS:000276574100171
ER
PT S
AU Grunschel, SE
Clifton, RJ
Jiao, T
AF Grunschel, S. E.
Clifton, R. J.
Jiao, T.
BE Elert, ML
Buttler, WT
Furnish, MD
Anderson, WW
Proud, WG
TI HIGH STRAIN-RATE RESPONSE OF HIGH-PURITY ALUMINUM AT TEMPERATURES
APPROACHING MELT
SO SHOCK COMPRESSION OF CONDENSED MATTER - 2009, PTS 1 AND 2
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 16th Conference of the American-Physical-Society-Topical-Group on Shock
Compression of Condensed Matter
CY JUN 28-JUL 03, 2009
CL Nashville, TN
SP Amer Phys Soc, Topical Grp
DE Aluminum; high strain rate; high temperature; plasticity
ID METALS
AB High-temperature, pressure-shear plate impact experiments were conducted to investigate the rate-controlling mechanisms of the plastic response of high-purity aluminum at high strain rates (10(6) s(-1)) and at temperatures approaching melt. Since the melting temperature of aluminum is pressure dependent, and a typical pressure-shear plate impact experiment subjects the sample to large pressures (2 - 7 GPa), a pressure-release type experiment was used to reduce the pressure in order to measure the shearing resistance at temperatures up to 95% of the current melting temperature. The measured shearing resistance was remarkably large (50 MPa at a shear strain of 2.5) for temperatures this near melt. Numerical simulations conducted using a version of the Nemat-Nasser/Isaacs [1] constitutive equation, modified to model the mechanism of geometric softening, appear to capture adequately the hardening/softening behavior observed experimentally.
C1 [Grunschel, S. E.; Clifton, R. J.; Jiao, T.] Brown Univ, Div Engn, Providence, RI 02912 USA.
[Grunschel, S. E.] US Army, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Grunschel, SE (reprint author), Brown Univ, Div Engn, Providence, RI 02912 USA.
FU NSFMRSEC at Brown University; Lawrence Livermore National Labs
FX The authors are grate fill for the support of NSFMRSEC at Brown
University and Lawrence Livermore National Labs.
NR 5
TC 2
Z9 2
U1 0
U2 4
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0732-9
J9 AIP CONF PROC
PY 2009
VL 1195
BP 949
EP +
PG 2
WC Physics, Condensed Matter
SC Physics
GA BOG48
UT WOS:000276574100225
ER
PT S
AU Casem, DT
Dandekar, DP
AF Casem, D. T.
Dandekar, D. P.
BE Elert, ML
Buttler, WT
Furnish, MD
Anderson, WW
Proud, WG
TI RESPONSE OF ALUMINUM 2139-T8 TO SHOCK LOADING
SO SHOCK COMPRESSION OF CONDENSED MATTER - 2009, PTS 1 AND 2
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 16th Conference of the American-Physical-Society-Topical-Group on Shock
Compression of Condensed Matter
CY JUN 28-JUL 03, 2009
CL Nashville, TN
SP Amer Phys Soc, Topical Grp
DE 2139 Aluminum; Hugoniot Elastic Limit; shear strength; spall strength
AB Plane shock wave experiments have been conducted on an aluminum alloy, Al 2139-T8, to determine its response under high rates of loading. The alloying elements, copper, magnesium, and silver, have been found to increase the strength, fatigue life, and fracture toughness of Al 2139-T8 and mitigate impact induced damage. The present experiments provide measurements of the Hugoniot Elastic Limit (HEL), shear strength, and spall threshold to almost 5 GPa. Longitudinal measurements are made with a VISAR system and shear strength is determined through direct measurements of lateral stress with embedded manganin gages. Preliminary results indicate an HEL of approximately 0.85 GPa and a constant spall-induced pull-back velocity of approximately 180 m/s. The results also show that 2139-T8 aluminum retains its shear strength under shock loading like other aluminum alloys.
C1 [Casem, D. T.; Dandekar, D. P.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Casem, DT (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
NR 10
TC 0
Z9 0
U1 0
U2 0
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0732-9
J9 AIP CONF PROC
PY 2009
VL 1195
BP 973
EP 976
PG 4
WC Physics, Condensed Matter
SC Physics
GA BOG48
UT WOS:000276574100231
ER
PT S
AU Dandekar, DP
Casem, DT
Motoyashiki, Y
Sato, E
AF Dandekar, D. P.
Casem, D. T.
Motoyashiki, Y.
Sato, E.
BE Elert, ML
Buttler, WT
Furnish, MD
Anderson, WW
Proud, WG
TI SHOCK RESPONSE OF SILICON NITRIDE
SO SHOCK COMPRESSION OF CONDENSED MATTER - 2009, PTS 1 AND 2
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 16th Conference of the American-Physical-Society-Topical-Group on Shock
Compression of Condensed Matter
CY JUN 28-JUL 03, 2009
CL Nashville, TN
SP Amer Phys Soc, Topical Grp
DE Shock response; silicon nitride; Hugoniot Elastic Limit; spall strength
AB Silicon nitride is suitable for varied applications because its properties can be tailored through processing and doping. The current work presents shock response of silicon nitride marketed as SN282. The density of this material, 3.4 Mg/m(3), exceeds its single crystal density, 3.2 Mg/m(3), due to the presence of lutetium oxide as an additive around 5% by weight in the material. While the average grain size is 3.4 microns, the aspect ratio of the grains exceed 3. Preliminary results of shock wave experiments may be summarized as follows: (1) The Hugoniot Elastic Limit (HEL) of SN282 lies between 10.8 and 11.9 GPa. (2) The magnitude of the inelastic wave velocity just above the HEL is 8.73 km/s, suggesting that inelastic deformation above the HEL is due to shock induced plasticity in the material. (3) The value of the spall strength lies between 0.57 and 0.65 GPa. The spall strength of SN282 remains unchanged even when shocked beyond the HEL to at least 19.2 GPa unlike other brittle ceramics.
C1 [Dandekar, D. P.; Casem, D. T.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
[Motoyashiki, Y.; Sato, E.] Inst Space & Astronaut Sci, Kanagawa 2298510, Japan.
RP Dandekar, DP (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
NR 9
TC 2
Z9 2
U1 0
U2 0
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0732-9
J9 AIP CONF PROC
PY 2009
VL 1195
BP 985
EP +
PG 2
WC Physics, Condensed Matter
SC Physics
GA BOG48
UT WOS:000276574100234
ER
PT S
AU Ciezak, JA
Dandekar, DP
AF Ciezak, J. A.
Dandekar, D. P.
BE Elert, ML
Buttler, WT
Furnish, MD
Anderson, WW
Proud, WG
TI COMPRESSION AND ASSOCIATED PROPERTIES OF BORON CARBIDE (B4C)
SO SHOCK COMPRESSION OF CONDENSED MATTER - 2009, PTS 1 AND 2
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 16th Conference of the American-Physical-Society-Topical-Group on Shock
Compression of Condensed Matter
CY JUN 28-JUL 03, 2009
CL Nashville, TN
SP Amer Phys Soc, Topical Grp
DE boron carbide; diamond anvil cell; shock compression
AB The observed loss of shear strength of boron carbide near 22 GPa has been attributed to presence of amorphous material in the shock recovered, and statically/dynamically indented B4C. This work shows presence of amorphization in boron carbide under triaxial stress compression. This evidence is obtained from in-situ measurement of Raman, and infrared vibrational spectra of B4C under hydrostatic and non-hydrostatic pressures. On the other hand, x-ray diffraction measurements show a shift in the compression of B4C around 27 GPa, but no evidence of a loss of crystallinity in the recorded diffraction pattern of B4C to 47 GPa. Our results indicate that shear plays a very dominant role in the stress-induced amorphization of B4C.
C1 [Ciezak, J. A.; Dandekar, D. P.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Ciezak, JA (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
NR 11
TC 1
Z9 1
U1 0
U2 1
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0732-9
J9 AIP CONF PROC
PY 2009
VL 1195
BP 1287
EP 1290
PG 4
WC Physics, Condensed Matter
SC Physics
GA BOG48
UT WOS:000276574100304
ER
PT S
AU Ciezak, JA
Jenkins, TA
Hemley, RJ
AF Ciezak, Jennifer A.
Jenkins, Timothy A.
Hemley, Russell J.
BE Elert, ML
Buttler, WT
Furnish, MD
Anderson, WW
Proud, WG
TI OPTICAL AND RAMAN MICROSPECTROSCOPY OF NITROGEN AND HYDROGEN MIXTURES AT
HIGH PRESSURES
SO SHOCK COMPRESSION OF CONDENSED MATTER - 2009, PTS 1 AND 2
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 16th Conference of the American-Physical-Society-Topical-Group on Shock
Compression of Condensed Matter
CY JUN 28-JUL 03, 2009
CL Nashville, TN
SP Amer Phys Soc, Topical Grp
DE nitrogen-hydrogen mixture; diamond anvil cell; Raman spectroscopy
ID HELIUM; GPA
AB Optical and Raman microspectroscopy measurements performed on N-2:H-2 mixtures to 83 GPa reveal unusual phase behavior and bonding signatures. To pressures of 30 GPa, large deviations in the internal molecular stretching modes (vibrons) of a 2:1 N-2:H-2, mixture relative to those of the pure materials are found. An unusual phase separation is observed near 35 GPa, involving the formation of two distinct solid phases, one rich in both nitrogen and hydrogen and the other an amorphous nitrogen phase. Raman bands attributed to N-N single bonds or polymerized nitrogen were observed at high pressures.
C1 [Ciezak, Jennifer A.] USA, Res Lab, AMSRD ARL WM BD, Aberdeen Proving Ground, MD 21005 USA.
[Jenkins, Timothy A.] NIST, Ctr Neutron Res, Gaithersburg, MD 20899 USA.
[Hemley, Russell J.] Carnegie Inst Sci, Geophys Lab, Washington, DC 20015 USA.
RP Ciezak, JA (reprint author), USA, Res Lab, AMSRD ARL WM BD, Aberdeen Proving Ground, MD 21005 USA.
FU Carnegie/DOE Alliance Center; National Science Foundation
FX Support for this project comes in part from the Carnegie/DOE Alliance
Center and the National Science Foundation.
NR 14
TC 5
Z9 5
U1 0
U2 2
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0732-9
J9 AIP CONF PROC
PY 2009
VL 1195
BP 1291
EP +
PG 2
WC Physics, Condensed Matter
SC Physics
GA BOG48
UT WOS:000276574100305
ER
PT S
AU Cazamias, JU
Bilyk, SR
AF Cazamias, J. U.
Bilyk, S. R.
BE Elert, ML
Buttler, WT
Furnish, MD
Anderson, WW
Proud, WG
TI CALIBRATING THE JOHNSON-HOLMQUIST CERAMIC MODEL FOR SIC USING CTH
SO SHOCK COMPRESSION OF CONDENSED MATTER - 2009, PTS 1 AND 2
SE AIP Conference Proceedings
LA English
DT Proceedings Paper
CT 16th Conference of the American-Physical-Society-Topical-Group on Shock
Compression of Condensed Matter
CY JUN 28-JUL 03, 2009
CL Nashville, TN
SP Amer Phys Soc, Topical Grp
DE Silicon carbide; CTH; ceramic; penetration; constitutive models
ID PENETRATION; IMPACT
AB The Johnson-Holmquist ceramic material model has been calibrated and successfully applied to numerically simulate ballistic events using the Lagrangian code EPIC. While the majority of the constants are "physics" based, two of the constants for the failed material response are calibrated using ballistic experiments conducted on a confined cylindrical ceramic target. The maximum strength of the failed ceramic is calibrated by matching the penetration velocity. The second refers to the equivalent plastic strain at failure under constant pressure and is calibrated using the dwell time. Use of these two constants in the CTH Eulerian hydrocode does not predict the ballistic response. This difference may be due to the phenomenological nature of the model and the different numerical schemes used by the codes. This paper determines the aforementioned material constants for SiC suitable for simulating ballistic events using CTH.
C1 [Cazamias, J. U.] Univ Alabama Birmingham, Birmingham, AL 35294 USA.
[Bilyk, S. R.] US Army, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Cazamias, JU (reprint author), Univ Alabama Birmingham, Birmingham, AL 35294 USA.
NR 18
TC 0
Z9 0
U1 0
U2 1
PU AMER INST PHYSICS
PI MELVILLE
PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA
SN 0094-243X
BN 978-0-7354-0732-9
J9 AIP CONF PROC
PY 2009
VL 1195
BP 1405
EP +
PG 2
WC Physics, Condensed Matter
SC Physics
GA BOG48
UT WOS:000276574100331
ER
PT J
AU Velo, AP
Gazonas, GA
Ameya, T
AF Velo, Ani P.
Gazonas, George A.
Ameya, Takanobu
TI z-TRANSFORM METHODS FOR THE OPTIMAL DESIGN OF ONE-DIMENSIONAL LAYERED
ELASTIC MEDIA
SO SIAM JOURNAL ON APPLIED MATHEMATICS
LA English
DT Article
DE Goupillaud-type layered media; transient loading; wave propagation;
shock wave; characteristic curves; palindromic polynomial; periodic
optimization; validation of numerical codes
ID MULTILAYER STRUCTURES; WAVES; INVERSION; EQUATIONS; SYSTEMS; MEMS
AB In this work, we develop a finite trigonometric series representation for the stress in a multilayered Goupillaud-type elastic strip subjected to transient Heaviside loading on one end while the other end is held fixed. This representation is achieved by means of the z-transform method and involves the so-called base angles. Generally, different layered designs could share the same set of base angles, and the more layers the design has, the more base angles are expected. Necessary conditions for the base angles and design parameters for any given design are described. As a result of the stress representation, we are able to identify optimal layered designs which provide the smallest stress amplitude. For two- and three-layered designs, for which the coefficients of the stress representation are easy to find, the optimization results are achieved using a custom-made discrete optimization technique applied in [A.P. Velo and G. A. Gazonas, Int. J. Solids Structures, 40 (2003), pp. 6417-6428]. For other layered designs, the optimality conditions are predicted heuristically using pattern recognition and the necessary conditions for the base angles and design parameters. Applications of these optimization results include design improvement in making a nonoptimal design optimal. They are also extended to non-Goupillaud-type layered media with integer layer length ratios. Our results are supported by numerical experiments and provide means to validate numerical optimization codes.
C1 [Velo, Ani P.; Ameya, Takanobu] Univ San Diego, Dept Math & Comp Sci, San Diego, CA 92110 USA.
[Gazonas, George A.] USA, Res Lab, Weap & Mat Res Directorate, Aberdeen, MD 21005 USA.
RP Velo, AP (reprint author), Univ San Diego, Dept Math & Comp Sci, 5998 Alcala Pk, San Diego, CA 92110 USA.
EM avelo@sandiego.edu; gazonas@arl.army.mil; tameya@sandiego.edu
OI Gazonas, George/0000-0002-2715-016X
FU Short Term Analysis Services (STAS); Faculty Research and Engineering
Program (FREP)
FX Received by the editors March 4, 2009; accepted for publication (in
revised form) May 5, 2009; published electronically July 22, 2009. This
research effort was partially sponsored by the Short Term Analysis
Services (STAS) and Faculty Research and Engineering Program (FREP),
administered by the Battelle Memorial Institute in North Carolina for
the U.S. Army Research Laboratory. This work was performed in part by an
employee of the U.S. Government or under U.S. Government contract. The
U.S. Government retains a nonexclusive, royalty-free license to publish
or reproduce the published form of this contribution, or allow others to
do so, for U.S. Government purposes. Copyright is owned by SIAM to the
extent not limited by these rights.
NR 36
TC 10
Z9 10
U1 0
U2 3
PU SIAM PUBLICATIONS
PI PHILADELPHIA
PA 3600 UNIV CITY SCIENCE CENTER, PHILADELPHIA, PA 19104-2688 USA
SN 0036-1399
EI 1095-712X
J9 SIAM J APPL MATH
JI SIAM J. Appl. Math.
PY 2009
VL 70
IS 3
BP 762
EP 788
DI 10.1137/090751608
PG 27
WC Mathematics, Applied
SC Mathematics
GA 499CC
UT WOS:000270193200007
ER
PT J
AU Chang, MH
Pang, T
Yong, JM
AF Chang, Mou-Hsiung
Pang, Tao
Yong, Jiongmin
TI OPTIMAL STOPPING PROBLEM FOR STOCHASTIC DIFFERENTIAL EQUATIONS WITH
RANDOM COEFFICIENTS
SO SIAM JOURNAL ON CONTROL AND OPTIMIZATION
LA English
DT Article
DE optimal stopping; random coefficients; dynamic programming principle;
backward stochastic partial differential variational inequality;
verification theorem
ID CONTINUOUS PARAMETER; SYSTEMS
AB An optimal stopping problem for stochastic differential equations with random coefficients is considered. The dynamic programming principle leads to a Hamiltion-Jacobi-Bellman equation, which, for the current case, is a backward stochastic partial differential variational inequality (BSPDVI, for short) for the value function. Well-posedness of such a BSPDVI is established, and a veri. cation theorem is proved.
C1 [Chang, Mou-Hsiung] USA, Res Off, Div Math, Res Triangle Pk, NC 27709 USA.
[Pang, Tao] N Carolina State Univ, Dept Math, Ctr Res Sci Computat, Raleigh, NC 27695 USA.
[Yong, Jiongmin] Univ Cent Florida, Dept Math, Orlando, FL 32816 USA.
RP Chang, MH (reprint author), USA, Res Off, Div Math, Res Triangle Pk, NC 27709 USA.
EM mouhsiung.chang@us.army.mil; tpang@unity.ncsu.edu; jyong@mail.ucf.edu
FU U. S. Army Research Office [W911NF04-D-0003]; NSF [DMS-0604309]
FX This work is supported in part by grant W911NF04-D-0003 from the U. S.
Army Research Office and by NSF grant DMS-0604309.
NR 29
TC 8
Z9 8
U1 0
U2 2
PU SIAM PUBLICATIONS
PI PHILADELPHIA
PA 3600 UNIV CITY SCIENCE CENTER, PHILADELPHIA, PA 19104-2688 USA
SN 0363-0129
J9 SIAM J CONTROL OPTIM
JI SIAM J. Control Optim.
PY 2009
VL 48
IS 2
BP 941
EP 971
DI 10.1137/070705726
PG 31
WC Automation & Control Systems; Mathematics, Applied
SC Automation & Control Systems; Mathematics
GA 441OM
UT WOS:000265778500024
ER
PT B
AU Mentis, AS
AF Mentis, Alexander S.
GP ACM
TI A Robotics API Dialect for Type-Safe Robots: Translating Myro to Ada
SO SIGADA 2009: PROCEEDINGS OF THE ACM INTERNATIONAL CONFERENCE ON ADA AND
RELATED TECHNOLOGIES
LA English
DT Proceedings Paper
CT ACM International Conference on Ada and Related Technologies
CY NOV 01-05, 2009
CL St Petersburg, FL
SP ACM SIGAda, ACM SIGCSE, ACM SIGAPP, ACM SIGBED, ACM SIGCAS, ACM SIGPLAN, Ada-Europe, AdaCore, Ellidiss Software & Lockheed Martin
DE Undergraduate computer science education; Myro; Scribbler
AB In this paper, we present an Ada robotics API designed to be used in teaching undergraduate-level computer science. Our API is inspired by Myro, a Python-based API, but we improve upon Myro's usability, readability, modularity, and documentation by using features of the Ada programming language and the GNAT Programming Studio's documentation generation tool. The encapsulation, abstraction, and data hiding provided by Ada's packages make it easy for beginning programmers to use the API for advanced tasks, while Ada's syntax and readability allow educators to use the underlying code later in a course or curriculum to illustrate more advanced concepts to the same students as their knowledge and experience grow.
C1 US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA.
RP Mentis, AS (reprint author), US Mil Acad, Dept Elect Engn & Comp Sci, West Point, NY 10996 USA.
EM alexander.mentis@usma.edu
NR 4
TC 0
Z9 0
U1 0
U2 0
PU ASSOC COMPUTING MACHINERY
PI NEW YORK
PA 1515 BROADWAY, NEW YORK, NY 10036-9998 USA
BN 978-1-60558-475-1
PY 2009
BP 91
EP 101
PG 11
WC Computer Science, Hardware & Architecture; Computer Science, Software
Engineering
SC Computer Science
GA BQR20
UT WOS:000281598400020
ER
PT S
AU Jones, K
Zheleva, T
Vispute, R
Hullavarad, S
Ervin, M
Dhar, S
AF Jones, K.
Zheleva, T.
Vispute, R.
Hullavarad, S.
Ervin, M.
Dhar, S.
BE Suzuki, A
Okumura, H
Kimoto, T
Fuyuki, T
Fukuda, K
Nishizawa, S
TI Epitaxial TAC Films for the Selective Area Growth of SiC
SO SILICON CARBIDE AND RELATED MATERIALS 2007, PTS 1 AND 2
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 12th International Conference on Silicon Carbide and Related Materials
CY OCT 14-19, 2007
CL Otsu, JAPAN
SP Japan Soc Appl Phys, Assoc Promot Elect, Elect & Informat Engn, Ceram Soc Japan, IEEE EDS, Kansai Chapter, IEEJ, Inst Elect, Informat & Commun Engineers, Japanese Assoc Crystal Growth, Surface Sci Soc Japan, Vacuum Soc Japan
DE TaC; SiC; selective area growth; AlGaN
ID DIODES
AB At sufficiently high temperatures PLD deposited TaC films can be grown epitaxially on 4H-SiC (0001) substrates; at lower temperatures the films recrystallize and ball up forming a large number of pinholes. The growth temperature for epitaxy was found to be 1000 degrees C, and it was facilitated by the epitaxial growth of a thin (2 nm) transition layer of hexagonal Ta2C. High temperature annealing produced changes in the surface morphology, caused grain growth, and created pin holes through a recrystallization process in the films deposited at the lower temperatures, while the films deposited at the higher temperatures remained virtually unchanged. Using TEM it is shown that the (0001) basal planes of the hexagonal 4H-SiC and Ta2C phases are aligned, and they were also parallel to the (111) plane in the cubic TaC with the [10 (1) over bar] cubic direction being parallel to the hexagonal [2 (11) over bar0] hexagonal direction. The Ta2C interlayer most likely is formed because its lattice parameter in the basel plane (3.103 angstrom) is intermediate between that of the 4H-SiC (3.08 angstrom) and the TaC (3.150 angstrom). Given that Al.5Ga.5N is lattice matched to TaC, it could be an excellent substrate for the growth of GaN/AlGaN heterostructures.
C1 [Jones, K.; Zheleva, T.; Ervin, M.] Army Res Lab SEDD, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
[Vispute, R.; Hullavarad, S.; Dhar, S.] Univ Maryland, Dept Phys, College Pk, MD 20742 USA.
RP Jones, K (reprint author), Army Res Lab SEDD, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM kajones@arl.army.mil; tzheleva@arl.army.mil; vispute@squid.umd.edu;
shiva@squid.umd.edu; mervin@arl.army.mil; sdhar@squid.umd.edu
NR 3
TC 1
Z9 1
U1 1
U2 1
PU TRANS TECH PUBLICATIONS LTD
PI DURNTEN-ZURICH
PA KREUZSTRASSE 10, 8635 DURNTEN-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 600-603
BP 183
EP +
PN 1-2
PG 2
WC Materials Science, Ceramics; Materials Science, Multidisciplinary
SC Materials Science
GA BIX26
UT WOS:000263555300044
ER
PT S
AU Jones, KA
AF Jones, K. A.
BE Suzuki, A
Okumura, H
Kimoto, T
Fuyuki, T
Fukuda, K
Nishizawa, S
TI Structural Analysis of Off-Axis SiC Planes for the Growth of SiC and
AlGaN Films
SO SILICON CARBIDE AND RELATED MATERIALS 2007, PTS 1 AND 2
SE Materials Science Forum
LA English
DT Proceedings Paper
CT International Conference on Silicon Carbide and Related Materials
CY OCT 14-19, 2007
CL Otsu, JAPAN
SP Japan Soc Appl phys, Assoc Promot Elect, Elect & Informat Engn, Ceram Soc Japan, IEEE EDS, Kansai Chapter, IEEJ, Inst Elect, Informat & Commun Engineers, Japanese Assoc Crystal Growth, Surface Sci Soc Japan, Vacuum Soc Japan
DE AlGaN films; SiC films; SiC substrates; misfit dislocations; stacking
faults
ID LIGHT-EMITTING-DIODES
AB An orientation relationship between the cubic 3C and nH hexagonal structures was developed to identify low surface energy, close packed, conducive to growth hexagonal semi-polar planes. This was done to identify planes on which micropipe free SiC crystals, and/or hetero-epitaxial AlGaN structures with a reduced piezoelectric field and a smaller lattice mismatch could be grown. The nH (3 (3) over bar 0 2n)(H) and (3 (3) over bar 0 (n) over bar)(H) hexagonal planes, which correspond to the (100)(C) and (11 (1) over bar)(C) cubic planes are identified, and equations are developed to determine their planar structure and packing density to assess whether there is a reasonable chance that high quality material can be grown on these surfaces and whether it is likely that stacking faults will be formed. It is shown that stacking faults will likely form in SiC crystals; it is also shown that good epitaxy of AlGaN films should be possible on these planes although it is likely stacking faults will be formed.
C1 Army Res Lab SEDD, Adelphi, MD 20783 USA.
RP Jones, KA (reprint author), Army Res Lab SEDD, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM kajones@arl.army.mil
NR 4
TC 1
Z9 1
U1 0
U2 0
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 600-603
BP 369
EP 372
PG 4
WC Materials Science, Ceramics; Materials Science, Multidisciplinary
SC Materials Science
GA BIX26
UT WOS:000263555300087
ER
PT S
AU Cochrane, CJ
Lenahan, PM
Lelis, AJ
AF Cochrane, C. J.
Lenahan, P. M.
Lelis, A. J.
BE Suzuki, A
Okumura, H
Kimoto, T
Fuyuki, T
Fukuda, K
Nishizawa, S
TI Electrically Detected Magnetic Resonance Studies of Processing
Variations in 4H SiC Based MOSFETs
SO SILICON CARBIDE AND RELATED MATERIALS 2007, PTS 1 AND 2
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 12th International Conference on Silicon Carbide and Related Materials
CY OCT 14-19, 2007
CL Otsu, JAPAN
SP Japan Soc Appl Phys, Assoc Promot Elect, Elect & Informat Engn, Ceram Soc Japan, IEEE EDS, Kansai Chapter, IEEJ, Inst Elect, Informat & Commun Engineers, Japanese Assoc Crystal Growth, Surface Sci Soc Japan, Vacuum Soc Japan
DE magnetic resonance; device reliability; MOSFET
ID SEMICONDUCTORS; RECOMBINATION
AB We apply electrically detected magnetic resonance (EDMR) to variously processed 4H SiC MOSFETs from two vendors. Although, the EDMR line shapes observed are nearly the same for vendor I devices subjected to a nitric oxide (NO) anneal and devices without it, the relationship between EDMR and gate voltage differs greatly between these samples. Furthermore, the EDMR response versus gate bias varies dramatically. EDMR results from a third device produced by a second vendor are very different from those provided by the first vendor. This result implies that significantly different defect populations are present in devices fabricated by different vendors.
C1 [Cochrane, C. J.; Lenahan, P. M.] Penn State Univ, 101 EES Bldg, University Pk, PA 16802 USA.
[Lelis, A. J.] US Army, Res Lab, Adelphi, MD 20783 USA.
RP Cochrane, CJ (reprint author), Penn State Univ, 101 EES Bldg, University Pk, PA 16802 USA.
EM cjc203@psu.edu; pmlesm@engr.psu.edu; alelis@arl.army.mil
NR 6
TC 5
Z9 5
U1 1
U2 3
PU TRANS TECH PUBLICATIONS LTD
PI DURNTEN-ZURICH
PA KREUZSTRASSE 10, 8635 DURNTEN-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 600-603
BP 719
EP +
PN 1-2
PG 2
WC Materials Science, Ceramics; Materials Science, Multidisciplinary
SC Materials Science
GA BIX26
UT WOS:000263555300172
ER
PT S
AU Habersat, DB
Lelis, AJ
McGarrity, JM
McLean, FB
Potbhare, S
AF Habersat, D. B.
Lelis, A. J.
McGarrity, J. M.
McLean, F. B.
Potbhare, S.
BE Suzuki, A
Okumura, H
Kimoto, T
Fuyuki, T
Fukuda, K
Nishizawa, S
TI The Effect of Nitridation on SiC MOS Oxides as Evaluated by Charge
Pumping
SO SILICON CARBIDE AND RELATED MATERIALS 2007, PTS 1 AND 2
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 12th International Conference on Silicon Carbide and Related Materials
CY OCT 14-19, 2007
CL Otsu, JAPAN
SP Japan Soc Appl Phys, Assoc Promot Elect, Elect & Informat Engn, Ceram Soc Japan, IEEE EDS, Kansai Chapter, IEEJ, Inst Elect, Informat & Commun Engineers, Japanese Assoc Crystal Growth, Surface Sci Soc Japan, Vacuum Soc Japan
DE MOS; MOSFET; interface traps; oxide traps; charge pumping; nitridation
ID TRANSISTORS; INTERFACE
AB We have analyzed the effect of post-oxidation nitride anneals (usually with either NO or N2O gases) on SiC MOSFETs. Two 4H:SiC wafers were identically prepared except that one wafer had a nitridation anneal after the gate oxide was formed, while the other was tested as-oxidized. We compared the two processes by making measurements on lateral MOSFETs and MOS capacitors using I-D-V-GS, C-V, and charge pumping. There was no change in either flatband voltage or interface trap density near the valence band, suggesting that the net fixed charge remained constant (within a few 10(11) cm(-2)). However, there was a large shift in the threshold voltage which, when combined with the C-V results, indicates a strong reduction of interface traps near the conduction band of roughly 6.0 x 10(12) cm(-2) by using the nitridation process. The charge pumping measurements also showed a strong reduction of interface traps. Charge pumping measured a trapping density of 2.5 x 10(12) cm(-2) for the as-oxidized samples and 5.3 x 10(11) cm(-2) for the nitrided samples. The frequency-dependence of the charge pumping signal also indicates a spatial distribution of traps, with volumetric trap densities of roughly 1.3 x 10(19) cm(-3) over 25 angstrom on as-oxidized and 3.8 x 10(18) cm(-3) over 19 angstrom for nitrided.
C1 [Habersat, D. B.; Lelis, A. J.] USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
[McGarrity, J. M.; McLean, F. B.] Berkeley Res Associates Inc, Springfield, VA 22150 USA.
[Potbhare, S.] Univ Maryland, College Pk, MD 20742 USA.
RP Habersat, DB (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM dhabersat@arl.army.mil; alelis@arl.army.mil; jmcgarrityarl@yahoo.com;
fbarrymc@verizon.net; potbhare@glue.umd.edu
NR 15
TC 11
Z9 11
U1 0
U2 4
PU TRANS TECH PUBLICATIONS LTD
PI DURNTEN-ZURICH
PA KREUZSTRASSE 10, 8635 DURNTEN-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 600-603
BP 743
EP +
PN 1-2
PG 2
WC Materials Science, Ceramics; Materials Science, Multidisciplinary
SC Materials Science
GA BIX26
UT WOS:000263555300178
ER
PT S
AU Lelis, AJ
Habersat, D
Green, R
Goldsman, N
AF Lelis, A. J.
Habersat, D.
Green, R.
Goldsman, N.
BE Suzuki, A
Okumura, H
Kimoto, T
Fuyuki, T
Fukuda, K
Nishizawa, S
TI Temperature-Dependence of SiC MOSFET Threshold-Voltage Instability
SO SILICON CARBIDE AND RELATED MATERIALS 2007, PTS 1 AND 2
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 12th International Conference on Silicon Carbide and Related Materials
CY OCT 14-19, 2007
CL Otsu, JAPAN
SP Japan Soc Appl Phys, Assoc Promot Elect, Elect & Informat Engn, Ceram Soc Japan, IEEE EDS, Kansai Chapter, IEEJ, Inst Elect, Informat & Commun Engineers, Japanese Assoc Crystal Growth, Surface Sci Soc Japan, Vacuum Soc Japan
DE MOSFET reliability; threshold voltage instability; oxide charge
AB We have observed variations in the instability in the threshold voltage, V-T, of SiC metaloxide semiconductor field-effect transistors (MOSFETs) from various sources and/or processes due to gate-bias stressing as a function of temperature. In some cases we see a dramatic increase in the instability with increasing temperature, consistent with interfacial charge trapping or de-trapping. In other cases the temperature response is very slight, and in still other cases we actually see VT instabilities that move in the opposite direction with bias, indicating the presence of mobile ions.
C1 [Lelis, A. J.; Habersat, D.; Green, R.] USA, Res Lab, Adelphi, MD 20783 USA.
[Goldsman, N.] Univ Maryland, College Pk, MD 20742 USA.
RP Lelis, AJ (reprint author), USA, Res Lab, Adelphi, MD 20783 USA.
EM alelis@arl.army.mil; dhabersat@arl.army.mil; rgreen@arl.army.mil;
neil@umd.edu
NR 4
TC 20
Z9 20
U1 1
U2 3
PU TRANS TECH PUBLICATIONS LTD
PI DURNTEN-ZURICH
PA KREUZSTRASSE 10, 8635 DURNTEN-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 600-603
BP 807
EP +
PN 1-2
PG 3
WC Materials Science, Ceramics; Materials Science, Multidisciplinary
SC Materials Science
GA BIX26
UT WOS:000263555300194
ER
PT S
AU Veliadis, V
McNutt, T
Mccoy, M
Hearne, H
DeSalvo, G
Clarke, C
Potyraj, P
Scozzie, C
AF Veliadis, Victor
McNutt, Ty
McCoy, Megan
Hearne, Harold
DeSalvo, Gregory
Clarke, Chris
Potyraj, Paul
Scozzie, Charles
BE Suzuki, A
Okumura, H
Kimoto, T
Fuyuki, T
Fukuda, K
Nishizawa, S
TI 1200-V, 50-A, Silicon Carbide Vertical Junction Field Effect Transistors
for Power Switching Applications
SO SILICON CARBIDE AND RELATED MATERIALS 2007, PTS 1 AND 2
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 12th International Conference on Silicon Carbide and Related Materials
CY OCT 14-19, 2007
CL Otsu, JAPAN
SP Japan Soc Appl Phys, Assoc Promot Elect, Elect & Informat Engn, Ceram Soc Japan, IEEE EDS, Kansai Chapter, IEEJ, Inst Elect, Informat & Commun Engineers, Japanese Assoc Crystal Growth, Surface Sci Soc Japan, Vacuum Soc Japan
DE JFET; large area; normally-on; high voltage; high current; high power
AB High-voltage normally-on VJFETs of 0.19 cm(2) and 0.096 cm(2) areas were manufactured in seven photolithographic levels with no epitaxial regrowth and a single ion implantation event. A self aligned guard ring structure provided edge termination. At a gate bias of -36 V the 0.096 cm(2) VJFET blocks 1980 V, which corresponds to 91% of the 12 mu m drift layer's avalanche breakdown voltage limit. It outputs 25 A at a forward drain voltage drop of 2 V (368 A/cm(2), 735 W/cm(2)) and a gate current of 4 mA. The specific on-resistance is 5.4 m Omega cm(2). The 0.19 cm(2) VJFET blocks 1200 V at a gate bias of -26 V. It outputs 54 A at a forward drain voltage drop of 2 V (378 A/cm(2), 755 W/cm(2)) and a gate current of 12 mA, with a specific on-resistance of 5.6 m Omega cm(2). The VJFETs demonstrated low gate-to-source leakage currents with sharp onsets of avalanche breakdown.
C1 [Veliadis, Victor; McNutt, Ty; McCoy, Megan; Hearne, Harold; DeSalvo, Gregory; Clarke, Chris; Potyraj, Paul] Northrop Grumman Adv Technol Lab, Linthicum, MD 21090 USA.
[Scozzie, Charles] Army Res Lab, Adelphi, MD 20783 USA.
RP Veliadis, V (reprint author), Northrop Grumman Adv Technol Lab, Linthicum, MD 21090 USA.
EM victor.veliadis@ngc.com; ty.mcnutt@ngc.com; megan.mccoy@ngc.com;
harold.hearne@ngc.com; greg.desalvo@ngc.com; chris.clarke@ngc.com;
paul.potyraj@ngc.com; sscozzie@arl.army.mil
NR 11
TC 6
Z9 8
U1 2
U2 2
PU TRANS TECH PUBLICATIONS LTD
PI DURNTEN-ZURICH
PA KREUZSTRASSE 10, 8635 DURNTEN-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 600-603
BP 1047
EP +
PN 1-2
PG 2
WC Materials Science, Ceramics; Materials Science, Multidisciplinary
SC Materials Science
GA BIX26
UT WOS:000263555300250
ER
PT S
AU Green, R
Ogunniyi, A
Ibitayo, D
Koebke, G
Morgenstern, M
Lelis, A
Dickens, C
Hull, B
AF Green, Ronald
Ogunniyi, Aderinto
Ibitayo, Dimeji
Koebke, Gail
Morgenstern, Mark
Lelis, Aivars
Dickens, Corey
Hull, Brett
BE Suzuki, A
Okumura, H
Kimoto, T
Fuyuki, T
Fukuda, K
Nishizawa, S
TI Evaluation of 4H-SiC DMOSFETs for High-Power Electronics Applications
SO SILICON CARBIDE AND RELATED MATERIALS 2007, PTS 1 AND 2
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 12th International Conference on Silicon Carbide and Related Materials
CY OCT 14-19, 2007
CL Otsu, JAPAN
SP Japan Soc Appl Phys, Assoc Promot Elect, Elect & Informat Engn, Ceram Soc Japan, IEEE EDS, Kansai Chapter, IEEJ, Inst Elect, Informat & Commun Engineers, Japanese Assoc Crystal Growth, Surface Sci Soc Japan, Vacuum Soc Japan
DE 4H-SiC; DMOSFET; Power Devices; Switching Loss
AB In this paper, large area (0.18cm(2)) SiC DMOSFETs with 1.2 kV and 20 A rating are evaluated for power electronic switching applications. A drain-to-source voltage drop V-DS of 2 V at a forward drain current of 20 A (J(D) = 110 A/cm(2)) was obtained and a specific on-resistance of 18 m Omega-cm(2) was extracted at room temperature. The device on-resistance was measured up to 150 degrees C and initially decreases with increasing temperature, but remains relatively flat over the entire temperature range, demonstrating stable device behavior. High voltage blocking of 1.2 kV between 25 degrees C and 150 degrees C is also demonstrated with a gate-to-source voltage V-GS = 0 V. The drain leakage current under reverse bias and high temperature stress is shown to increase from 10 mu A at 25 degrees C to 27 mu A at 150 degrees C while maintaining the full blocking rating of the device. Experimental results from double-pulse clamped inductive load tests are presented demonstrating fast high voltage and high current switching capability. High voltage resistive-switching measurements on parallel connected SiC DMOSFETs were performed with V-DS having rise and fall times of 49 and 74 ns respectively. Thermal camera images taken of parallel connected DMOSFET die during repetitive switching operation with V-DS = 420 V, I-DS = 25 A and a 40% duty cycle shows a 2 degrees C difference in die temperature, which suggests even current sharing and temperature stable device operation.
C1 [Green, Ronald; Ogunniyi, Aderinto; Ibitayo, Dimeji; Koebke, Gail; Morgenstern, Mark; Lelis, Aivars] Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
[Dickens, Corey] Morgan State Univ, Baltimore, MD 21251 USA.
[Hull, Brett] Cree Inc, Durham, NC 27703 USA.
RP Green, R (reprint author), Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM argreen@arl.army.mil; baderinto.ogunniyi@arl.army.mil;
cdibitayo@arl.army.mil; dgkoebke@arl.army.mil;
emmorgenstern@ari.army.mil; falelis@arl.army.mil;
gcdicken1@eng.morgan.edu; hbrett_hull@cree.com
NR 4
TC 1
Z9 1
U1 0
U2 1
PU TRANS TECH PUBLICATIONS LTD
PI DURNTEN-ZURICH
PA KREUZSTRASSE 10, 8635 DURNTEN-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 600-603
BP 1135
EP +
PN 1-2
PG 2
WC Materials Science, Ceramics; Materials Science, Multidisciplinary
SC Materials Science
GA BIX26
UT WOS:000263555300272
ER
PT S
AU Zhang, QC
Jonas, C
Burk, A
Capell, C
Young, J
Callanan, R
Agarwal, A
Palmour, J
Geil, B
Scozzie, C
AF Zhang, Qingchun (Jon)
Jonas, Charlotte
Burk, Al
Capell, Craig
Young, Jonathan
Callanan, Robert
Agarwal, Anant
Palmour, John
Geil, Bruce
Scozzie, Charles
BE Suzuki, A
Okumura, H
Kimoto, T
Fuyuki, T
Fukuda, K
Nishizawa, S
TI 4H-SiC Bipolar Junction Transistors with A Current Gain of 108
SO SILICON CARBIDE AND RELATED MATERIALS 2007, PTS 1 AND 2
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 12th International Conference on Silicon Carbide and Related Materials
CY OCT 14-19, 2007
CL Otsu, JAPAN
SP Japan Soc Appl Phys, Assoc Promot Elect, Elect & Informat Engn, Ceram Soc Japan, IEEE EDS, Kansai Chapter, IEEJ, Inst Elect, Informat & Commun Engineers, Japanese Assoc Crystal Growth, Surface Sci Soc Japan, Vacuum Soc Japan
DE SiC; Bipolar Junction Transistor; Current Gain; On-resistance; BVCEO;
BVCBO
AB 4H-SiC BJTs with a common emitter current gain (beta) of 108 at 25 degrees C have been demonstrated. The high current gain was accomplished by using a base as thin as 0.25 mu m. The current gain decreases at high temperatures but is still greater than 40 at 300 degrees C. The device demonstrates an open emitter breakdown voltage (BVCBO) of 1150 V, and an open base breakdown voltage (BVCEO) of 250 V. A low specific on-resistance of 3.6 m Omega.cm(2) at 25 degrees C was achieved. The BJTs have shown blocking capabilities over a wide range of operating temperatures up to 300 degrees C.
C1 [Zhang, Qingchun (Jon); Jonas, Charlotte; Burk, Al; Capell, Craig; Young, Jonathan; Callanan, Robert; Agarwal, Anant; Palmour, John] Cree Inc, 3026 E Cornwallis Rd, Res Triangle Pk, NC 27709 USA.
[Geil, Bruce; Scozzie, Charles] Army Res Lab, Adelphi, MD 20783 USA.
RP Zhang, QC (reprint author), Cree Inc, 3026 E Cornwallis Rd, Res Triangle Pk, NC 27709 USA.
EM Jon_Zhang@cree.com
FU Army Research Laboratory in Adelphi, Md [W911NF-04-2-0022]
FX This research was funded through the Cooperative Agreement
W911NF-04-2-0022 program supported by the Army Research Laboratory in
Adelphi, Md. Authors are grateful to Dr. S-H. Ryu for the valuable
technical discussion and manuscript reviewing.
NR 5
TC 1
Z9 1
U1 0
U2 0
PU TRANS TECH PUBLICATIONS LTD
PI DURNTEN-ZURICH
PA KREUZSTRASSE 10, 8635 DURNTEN-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 600-603
BP 1159
EP +
PN 1-2
PG 2
WC Materials Science, Ceramics; Materials Science, Multidisciplinary
SC Materials Science
GA BIX26
UT WOS:000263555300278
ER
PT S
AU Kaplan, SL
Ogunniyi, A
AF Kaplan, Steven L.
Ogunniyi, Aderinto
BE Suzuki, A
Okumura, H
Kimoto, T
Fuyuki, T
Fukuda, K
Nishizawa, S
TI Reliability Testing of 4H-SiC Bipolar Junction Transistors in Continuous
Switching Applications
SO SILICON CARBIDE AND RELATED MATERIALS 2007, PTS 1 AND 2
SE Materials Science Forum
LA English
DT Proceedings Paper
CT International Conference on Silicon Carbide and Related Materials
CY OCT 14-19, 2007
CL Otsu, JAPAN
SP Japan Soc Appl phys, Assoc Promot Elect, Elect & Informat Engn, Ceram Soc Japan, IEEE EDS, Kansai Chapter, IEEJ, Inst Elect, Informat & Commun Engineers, Japanese Assoc Crystal Growth, Surface Sci Soc Japan, Vacuum Soc Japan
DE silicon carbide; bipolar; junction; transistor; reliability; switching
AB Continued improvement in silicon carbide (SiC) material processing has allowed development of efficient high temperature devices which are uniquely suited to power electronics circuit designs. The 4H-SiC structure has several intrinsic characteristics that facilitate optimal speed and power handling during high temperature device operation. These characteristics include wide bandgap (3.2 eV), high dielectric breakdown (3.5 MV/cm), and high thermal conductivity (4.9 W/cm-K)[1,2]. By combining these properties, SiC bipolar junction transistors (BJTs) can achieve fast, low impedance switching at high voltages (1.2 kV). New generation devices are being developed with increased current handling capability, as well as improved forward voltage characteristics. The device considered here, along with its on-state DC characteristic, is shown in figure 1. The BJTs are approximately 5mm by 5mm, and are nominally rated for a maximum I., of 50A. Measurements on the Tektronix 371 B curve-tracer indicate current gains over 60 at 25 degrees C and roughly 40 at 150 degrees C. These results were obtained at collector currents up to 20A. The base current for BJTs is typically 300 to 800 mA, depending on device temperature and the maximum device current required. In order to meet current handling requirements of up to 80A, as required for power conversion in modern military systems such as the hybrid-electric vehicle (HEV), it is necessary to configure these devices in parallel with minimal external cooling. The resulting switching circuits must therefore be validated for operation at high temperatures (package temperatures of 90 degrees C, and junction temperatures to 150 degrees C). Validation includes characterization of the devices in clamped inductive circuits with devices configured both alone and in parallel over time. Figure 4 shows measurement waveforms obtained during continuous clamped inductive switching. The primary focus of this work is to establish the overall performance and reliability of these newer generation SiC BJTs in power conversion circuits. Failure analysis and critical performance issues, such as current sharing, energy loss, and total reverse recovery charge are addressed. The initial results of the experiments indicate that these SiC switches have the potential to perform reliably in high temperature power conversion.
C1 [Kaplan, Steven L.; Ogunniyi, Aderinto] USA, Res Lab, Adelphi, MD 20783 USA.
RP Kaplan, SL (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM skaplan@arl.army.mil; aderinto.ogunniyi@arl.army.mil
NR 2
TC 0
Z9 0
U1 0
U2 3
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 600-603
BP 1167
EP 1170
PG 4
WC Materials Science, Ceramics; Materials Science, Multidisciplinary
SC Materials Science
GA BIX26
UT WOS:000263555300280
ER
PT S
AU Cochrane, CJ
Lenahan, PM
Lelis, AJ
AF Cochrane, C. J.
Lenahan, P. M.
Lelis, A. J.
BE PerezTomas, A
Godignon, P
Vellvehi, M
Brosselard, P
TI Direct Observation of Lifetime Killing Defects in 4H SiC Epitaxial
Layers via Spin Dependent Recombination in Transistors
SO SILICON CARBIDE AND RELATED MATERIALS 2008
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 7th European Conference on Silicon Carbide and Related Materials
CY SEP 07-11, 2008
CL Barcelona, SPAIN
SP Minist Educ & Cienc, ACCIO, Generalitat Catalunya, ACREO, Aixtron, Cree Inc, Dow Corning, D plus T Microelect, Ion Beam Serv, SiCED, SiCrystal AG
DE recombination centers; lifetime killing defects; ESR; EPR; SDR
AB We have identified a magnetic resonance spectrum associated with minority carrier lifetime killing defects in device quality 4H SiC.
C1 [Cochrane, C. J.; Lenahan, P. M.] Penn State Univ, University Pk, PA 16802 USA.
[Lelis, A. J.] USA, Res Lab, Adelphi, MD 20783 USA.
RP Cochrane, CJ (reprint author), Penn State Univ, University Pk, PA 16802 USA.
EM pmlesm@engr.psu.edu
NR 20
TC 0
Z9 0
U1 0
U2 0
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 615-617
BP 299
EP 302
PG 4
WC Engineering, Electrical & Electronic; Materials Science, Ceramics;
Materials Science, Multidisciplinary
SC Engineering; Materials Science
GA BJH84
UT WOS:000265961100071
ER
PT S
AU Veliadis, V
Hearne, H
McNutt, T
Snook, M
Potyraj, P
Scozzie, C
AF Veliadis, Victor
Hearne, Harold
McNutt, Ty
Snook, Megan
Potyraj, Paul
Scozzie, Charles
BE PerezTomas, A
Godignon, P
Vellvehi, M
Brosselard, P
TI VJFET based all-SiC Normally-Off Cascode Switch for High Temperature
Power Handling Applications
SO SILICON CARBIDE AND RELATED MATERIALS 2008
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 7th European Conference on Silicon Carbide and Related Materials
CY SEP 07-11, 2008
CL Barcelona, SPAIN
SP Minist Educ & Cienc, ACCIO, Generalitat Catalunya, ACREO, Aixtron, Cree Inc, Dow Corning, D plus T Microelect, Ion Beam Serv, SiCED, SiCrystal AG
DE silicon carbide; vertical-channel junction field-effect transistor;
cascode switch; normally-off; high temperature; threshold voltage;
transconductance
AB High-voltage vertical-junction-field-effect-transistors (VJFETs) are typically designed normally-on to ensure low-resistance voltage-control operation at high current-gain. To exploit the high-voltage/temperature capabilities of VJFETs in a normally-off voltage-controlled switch, high-voltage normally-on and low-voltage normally-off VJFETs were connected in the cascode configuration. The cascode gate's threshold voltage decreases from 2.5 V to 2 V as the temperature increases from 25 degrees C to 225 degrees C, while its breakdown voltage increases from -23 V to -19 V. At 300 degrees C. the drain current of the cascode switch is 21.4% of its 25 degrees C value, which agrees well with the reduction of the 4H-SiC electron mobility with temperature. The VJFET based all-SiC cascode switch is normally-off at 300 degrees C, with its threshold voltage shifting from 1.6 V to 0.9 V as the temperature increases from 25 degrees C to 300 degrees C. This agrees well with the measured reduction in VJFET built-in potential. Finally, the reduction in cascode transconductance with temperature follows that of the theoretical 4H-SiC electron mobility. Overall, the measured thermally-induced cascode parameter shifts are in excellent agreement with theory, which signifies fabrication of robust SiC VJFETs for power switching applications
C1 [Veliadis, Victor; Hearne, Harold; McNutt, Ty; Snook, Megan; Potyraj, Paul] Northrop Grumman Elect Syst, Linthicum, MD 21090 USA.
[Scozzie, Charles] USA, Res Lab, Adelphi, MD 20783 USA.
RP Veliadis, V (reprint author), Northrop Grumman Elect Syst, 1212 Winterson Rd, Linthicum, MD 21090 USA.
EM victor.veliadis@ngc.com; harold.hearne@ngc.com; ty.mcnutt@ngc.com;
megan.snook@ngc.com; paul.potyraj@ngc.com; sscozzie@arl.army.mil
NR 6
TC 6
Z9 6
U1 0
U2 1
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 615-617
BP 711
EP 714
PG 4
WC Engineering, Electrical & Electronic; Materials Science, Ceramics;
Materials Science, Multidisciplinary
SC Engineering; Materials Science
GA BJH84
UT WOS:000265961100172
ER
PT S
AU Veliadis, V
Hearne, H
Stewart, EJ
Caldwell, JD
Snook, M
McNutt, T
Potyraj, P
Scozzie, C
AF Veliadis, Victor
Hearne, Harold
Stewart, Eric J.
Caldwell, Joshua D.
Snook, Megan
McNutt, Ty
Potyraj, Paul
Scozzie, Charles
BE PerezTomas, A
Godignon, P
Vellvehi, M
Brosselard, P
TI Effect of Bipolar Gate-to-drain Current on the Electrical Properties of
Vertical Junction Field Effect Transistors
SO SILICON CARBIDE AND RELATED MATERIALS 2008
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 7th European Conference on Silicon Carbide and Related Materials
CY SEP 07-11, 2008
CL Barcelona, SPAIN
SP Minist Educ & Cienc, ACCIO, Generalitat Catalunya, ACREO, Aixtron, Cree Inc, Dow Corning, D plus T Microelect, Ion Beam Serv, SiCED, SiCrystal AG
DE silicon carbide; stacking faults; reliability; power JFETs; stressing;
degradation; annealing; stacking fault shrinking
ID CASCODE
AB Electron-hole recombination-induced stacking faults have been shown to degrade the I-V characteristics of SiC power p-n diodes and DMOSFETs with thick drift epitaxial layers. In this paper, we investigate the effect of bipolar gate-to-drain Current on vertical-channel JFETs. The devices have n(-) drift epitaxial layers of 12-mu m and 100-mu m thicknesses, and were stressed at a Fixed gate-to-drain current density of 100 A/cm(2) for 500 hrs and 5 hrs, respectively. Significant gate-to-drain and on-state conduction current degradations were observed after stressing the 100-mu m drift VJFET. Annealing at 350 degrees C reverses the stress induced degradations. After 500 hours of stressing,. the gate-to-source, gate-to-drain, and blocking voltage characteristics of the 12-mu m VJFET remain unaffected. However, the on-state drain Current was 79% of its pro-stress value. Annealing at 350 degrees C has no impact on the post-stress on-state drain Current of the 12-mu m VJFET. This leads us 10 attribute the degradation to a "burn-in" effect.
C1 [Veliadis, Victor; Hearne, Harold; Stewart, Eric J.; Snook, Megan; McNutt, Ty; Potyraj, Paul] Northrop Grumman Elect Syst, Linthicum, MD 21090 USA.
[Caldwell, Joshua D.] USN, Res Lab, Washington, DC 20375 USA.
[Scozzie, Charles] USA, Res Lab, Adelphi, MD 20783 USA.
RP Veliadis, V (reprint author), Northrop Grumman Elect Syst, 1212 Winterson Rd, Linthicum, MD 21090 USA.
EM victor.veliadis@ngc.com; harold.hearne@ngc.com; eric.j.stewart@ngc.com;
joshua.caldwell@nrl.navy.mil; megan.snook@ngc.com; ty.mcnutt@ngc.com;
gpaul.potyraj@ngc.com; sscozzie@arl.army.mil
RI Caldwell, Joshua/B-3253-2008
OI Caldwell, Joshua/0000-0003-0374-2168
NR 11
TC 6
Z9 6
U1 0
U2 0
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 615-617
BP 719
EP 722
PG 4
WC Engineering, Electrical & Electronic; Materials Science, Ceramics;
Materials Science, Multidisciplinary
SC Engineering; Materials Science
GA BJH84
UT WOS:000265961100174
ER
PT S
AU Ryu, SH
Dhar, S
Haney, S
Agarwal, A
Lelis, A
Geil, B
Scozzie, C
AF Ryu, Sei-Hyung
Dhar, Sarit
Haney, Sarah
Agarwal, Anant
Lelis, Aivars
Geil, Bruce
Scozzie, Charles
BE PerezTomas, A
Godignon, P
Vellvehi, M
Brosselard, P
TI Critical Issues for MOS Based Power Devices in 4H-SiC
SO SILICON CARBIDE AND RELATED MATERIALS 2008
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 7th European Conference on Silicon Carbide and Related Materials
CY SEP 07-11, 2008
CL Barcelona, SPAIN
SP Minist Educ & Cienc, ACCIO, Generalitat Catalunya, ACREO, Aixtron, Cree Inc, Dow Corning, D plus T Microelect, Ion Beam Serv, SiCED, SiCrystal AG
DE power DMOSFET; threshold voltage; MOS channel; field effect mobility
ID DMOSFETS
AB In this paper, we present the effects of MOS channel processing on the threshold voltage and the MOS field effect mobility of 4H-SiC MOSFETs. By increasing the p-well doping concentration by two orders of magnitude, the threshold voltage could be shifted positive from 0V to 5 V when a thermal oxide layer with NO post oxidation anneal Was used as the gate dielectric layer. However, a severe degradation of MOS field effect mobility, decreasing from 37 cm(2)/Vs to 5 cm(2)/Vs, was also observed. Using a different processing technique, which uses a deposited oxide layer with an NO anneal, a threshold voltage of 7.5 V and a MOS field effect mobility of 15 cm(2)/Vs could be achieved. A 10 kV, 1 A power DMOSFET was demonstrated with this technique. A DMOSFET turn-off voltage of 5.25 V was measured at room temperature. which shifted to 3.0 V at 250 degrees C, providing acceptable noise margins throughout the operating temperature range.
C1 [Ryu, Sei-Hyung; Dhar, Sarit; Haney, Sarah; Agarwal, Anant] Cree Inc, Durham, NC 27703 USA.
[Lelis, Aivars; Geil, Bruce; Scozzie, Charles] USA, Res Lab, Adelphi, MD 20783 USA.
RP Ryu, SH (reprint author), Cree Inc, 4600 Silicon Dr, Durham, NC 27703 USA.
EM sei-hyung_ryu@cree.com
NR 6
TC 26
Z9 26
U1 0
U2 0
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 615-617
BP 743
EP 748
PG 6
WC Engineering, Electrical & Electronic; Materials Science, Ceramics;
Materials Science, Multidisciplinary
SC Engineering; Materials Science
GA BJH84
UT WOS:000265961100180
ER
PT S
AU Hull, BA
Jonas, C
Ryu, SH
Das, M
O'Loughlin, M
Husna, F
Callanan, R
Richmond, J
Agarwal, A
Palmour, J
Scozzie, C
AF Hull, Brett A.
Jonas, Charlotte
Ryu, Sei-Hyung
Das, Mrinal
O'Loughlin, Michael
Husna, Fatima
Callanan, Robert
Richmond, Jim
Agarwal, Anant
Palmour, John
Scozzie, Charles
BE PerezTomas, A
Godignon, P
Vellvehi, M
Brosselard, P
TI Performance of 60 A, 1200 V 4H-SiC DMOSFETs
SO SILICON CARBIDE AND RELATED MATERIALS 2008
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 7th European Conference on Silicon Carbide and Related Materials
CY SEP 07-11, 2008
CL Barcelona, SPAIN
SP Minist Educ & Cienc, ACCIO, Generalitat Catalunya, ACREO, Aixtron, Cree Inc, Dow Corning, D plus T Microelect, Ion Beam Serv, SiCED, SiCrystal AG
DE power DMOSFET; power semiconductor device; MOS transistor
AB Large area (8 mm x 7 mm) 1200 V 4H-SiC DMOSFETs with a specific on-resistance as low as 9 m Omega(.)cm(2) 2 (at V(GS) = 20 V) able to conduct 60 A at a power dissipation of 200 W/cm(2) are presented. On-resistance is fairly stable with temperature, increasing from 11.5 (at VGS 15 V) at 25 degrees C to 14 m Omega(.)cm(2) at 150 degrees C. The DMOSFETs exhibit avalanche breakdown at 1600 V with the gate shorted to the source, although sub-breakdown leakage currents up to 50 mu A are observed at 1200 V and 200 degrees C due to the threshold voltage lowering with temperature. When switched with a clamped inductive load circuit from 65 A conducting to 750 V blocking the turn-on and turn-off energies at 150 degrees C were less than 4.5 mJ.
C1 [Hull, Brett A.; Jonas, Charlotte; Ryu, Sei-Hyung; Das, Mrinal; O'Loughlin, Michael; Husna, Fatima; Callanan, Robert; Richmond, Jim; Agarwal, Anant; Palmour, John] Cree Inc, Durham, NC 27703 USA.
[Scozzie, Charles] Army Res Lab, Adelphi, MD 20783 USA.
RP Hull, BA (reprint author), Cree Inc, 4600 Silicon Dr, Durham, NC 27703 USA.
EM brett_hull@cree.com
NR 5
TC 17
Z9 17
U1 0
U2 1
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 615-617
BP 749
EP 752
PG 4
WC Engineering, Electrical & Electronic; Materials Science, Ceramics;
Materials Science, Multidisciplinary
SC Engineering; Materials Science
GA BJH84
UT WOS:000265961100181
ER
PT S
AU Habersat, DB
Lelis, AJ
Potbhare, S
Goldsman, N
AF Habersat, D. B.
Lelis, A. J.
Potbhare, S.
Goldsman, N.
BE PerezTomas, A
Godignon, P
Vellvehi, M
Brosselard, P
TI Improvements In SiC MOS Processing As Revealed By Studies of Fixed and
Oxide Trap Charge
SO SILICON CARBIDE AND RELATED MATERIALS 2008
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 7th European Conference on Silicon Carbide and Related Materials
CY SEP 07-11, 2008
CL Barcelona, SPAIN
SP Minist Educ & Cienc, ACCIO, Generalitat Catalunya, ACREO, Aixtron, Cree Inc, Dow Corning, D plus T Microelect, Ion Beam Serv, SiCED, SiCrystal AG
DE MOSFET; charge separation; interface trap; oxide trap; fixed charge
ID INTERFACE TRAPS; TRANSISTORS; RADIATION; MOSFETS; SILICON; VOLTAGE
AB In order to improve Silicon Carbide MOSFET device performance, it is important to minimize the on-state losses by improving the effective channel mobility, which can be done by decreasing interfacial charge consisting of interface traps. fixed charge, and oxide traps, which degrade mobility due to Coulombic scattering. This paper considers a method for distinguishing between oxide traps and fixed charge, and discusses how this charge has varied with processing over the last several years. Our results show that, over the period of study, N(F) has trended downward. Also, the number of switching oxide traps, which gives a lower bound for N(ot) appears to have decreased considerably. The trends For improvement in N(F) and Delta N(ot) are promising, but out data suggests that N(F) and N(ot) remain much too high and need to be reduced further to realize significant gains in SiC MOSFET performance.
C1 [Habersat, D. B.; Lelis, A. J.] USA, Res Lab, Adelphi, MD 20783 USA.
[Potbhare, S.; Goldsman, N.] Univ Maryland, College Pk, MD 20742 USA.
RP Habersat, DB (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM daniel.habersat@us.army.mil
NR 16
TC 3
Z9 3
U1 1
U2 2
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 615-617
BP 769
EP 772
PG 4
WC Engineering, Electrical & Electronic; Materials Science, Ceramics;
Materials Science, Multidisciplinary
SC Engineering; Materials Science
GA BJH84
UT WOS:000265961100186
ER
PT S
AU Potbhare, S
Goldsman, N
Akturk, A
Lelis, A
Green, R
AF Potbhare, Siddharth
Goldsman, Neil
Akturk, Akin
Lelis, Aivars
Green, Ronald
BE PerezTomas, A
Godignon, P
Vellvehi, M
Brosselard, P
TI Investigation of On and Off State Characteristics of 4H-SiC DMOSFETs
SO SILICON CARBIDE AND RELATED MATERIALS 2008
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 7th European Conference on Silicon Carbide and Related Materials
CY SEP 07-11, 2008
CL Barcelona, SPAIN
SP Minist Educ & Cienc, ACCIO, Generalitat Catalunya, ACREO, Aixtron, Cree Inc, Dow Corning, D plus T Microelect, Ion Beam Serv, SiCED, SiCrystal AG
DE 4H-SiC DMOSFET; on-resistance; device modeling; impact-ionization;
avalanche breakdown
ID CARBIDE
AB We build upon our previous work on 4H SiC lateral MOSFETs to present physics based numerical modeling and characterization of a 4H-SiC DMOSFET operating in ON state, Comparison of simulated ON state characteristics to experiment shows that surface roughness scattering dominates at the operating bias of V(GS)=15V, whereas interface trap density contributes to reducing the inversion charge in the channel and thereby increasing the ON resistance. OFF state performance of the DMOSFET was modeled by considering impact ionization in the device. Excellent leakage characteristics were observed with the device blocking 2kV drain voltage. Impact ionization related breakdown was observed at 2048V drain bias.
C1 [Potbhare, Siddharth; Goldsman, Neil; Akturk, Akin] Univ Maryland, College Pk, MD 20742 USA.
[Lelis, Aivars; Green, Ronald] USA, Res Lab, Adelphi, MD 20783 USA.
RP Potbhare, S (reprint author), Univ Maryland, College Pk, MD 20742 USA.
EM potbhare@umd.edu; neil@umd.edu; akturka@umd.edu; alelis@arl.army.mil;
rgreen@arl.army.mil
NR 4
TC 1
Z9 1
U1 0
U2 1
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 615-617
BP 805
EP 808
PG 4
WC Engineering, Electrical & Electronic; Materials Science, Ceramics;
Materials Science, Multidisciplinary
SC Engineering; Materials Science
GA BJH84
UT WOS:000265961100195
ER
PT S
AU Lelis, AJ
Habersat, D
Green, R
Goldsman, N
AF Lelis, A. J.
Habersat, D.
Green, R.
Goldsman, N.
BE PerezTomas, A
Godignon, P
Vellvehi, M
Brosselard, P
TI Implications of Threshold-Voltage Instability on SiC DMOSFET Operation
SO SILICON CARBIDE AND RELATED MATERIALS 2008
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 7th European Conference on Silicon Carbide and Related Materials
CY SEP 07-11, 2008
CL Barcelona, SPAIN
SP Minist Educ & Cienc, ACCIO, Generalitat Catalunya, ACREO, Aixtron, Cree Inc, Dow Corning, D plus T Microelect, Ion Beam Serv, SiCED, SiCrystal AG
DE charge trapping; MOSFET; leakage current; on-state resistance
ID MOSFETS
AB Although recent fast I-V measurements and Subthreshold analysis reveal that the threshold-voltage instability due to low-field bias stressing at roorn temperature is greater than previously reported when calculated using slower, standard measurements by a parameter analyzer-a result that is consistent with electrons directly tunneling into and out near interfacial oxide traps, this effect will not prevent the use of power SiC DMOSFET switches in power converter applications if certain precautions are followed. Namely, if the threshold voltage is set high enough so that a negative shift in threshold voltage will not increase the leakage current in the off-state, then the primary effect will be to increase the oil-state resistance by decreasing the effective gate voltage. The instability due to ON-state stressing is greater than that for bias stressing alone, but not significantly. For a well behaved device, a 1-hour ON-state stress will result in about a 7 percent increase in conduction losses, which is manageable for power converter applications.
C1 [Lelis, A. J.; Habersat, D.; Green, R.] USA, Res Lab, Adelphi, MD 20783 USA.
[Goldsman, N.] Univ Maryland, College Pk, MD 20742 USA.
RP Lelis, AJ (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM alelis@arl.army.mil; dahabersat@arl.army.mil; rgreen@arl.army.mil;
neil@umd.edu
NR 11
TC 5
Z9 5
U1 0
U2 0
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 615-617
BP 809
EP 812
PG 4
WC Engineering, Electrical & Electronic; Materials Science, Ceramics;
Materials Science, Multidisciplinary
SC Engineering; Materials Science
GA BJH84
UT WOS:000265961100196
ER
PT S
AU Yu, LC
Cheung, KP
Suehle, JS
Campbell, JP
Sheng, K
Lelis, AJ
Ryu, SH
AF Yu, Liangchun
Cheung, Kin P.
Suehle, John S.
Campbell, Jason P.
Sheng, Kuang
Lelis, Aivars J.
Ryu, Sei-Hyung
BE PerezTomas, A
Godignon, P
Vellvehi, M
Brosselard, P
TI Channel Hot-Carrier Effect of 4H-SiC MOSFET
SO SILICON CARBIDE AND RELATED MATERIALS 2008
SE Materials Science Forum
LA English
DT Proceedings Paper
CT 7th European Conference on Silicon Carbide and Related Materials
CY SEP 07-11, 2008
CL Barcelona, SPAIN
SP Minist Educ & Cienc, ACCIO, Generalitat Catalunya, ACREO, Aixtron, Cree Inc, Dow Corning, D plus T Microelect, Ion Beam Serv, SiCED, SiCrystal AG
DE channel hot-carrier effect; MOSFET; 4H-SiC
ID DEPENDENCE
AB SiC MOSFET, as power device, can be expected to operate with high drain and high gate voltages, possibly leading to hot-carrier effect. However, hot-carrier degradation in a SiC MOSFET is difficult to detect because the as fabricated devices contain high level of defects. We report, for the first time, evidence of hot-carrier effect in 4H-SiC MOSFET. The result Suggests that hot hole from impact ionization trapped in the oxide is the cause of the channel hot-carrier effect.
C1 [Yu, Liangchun; Cheung, Kin P.; Suehle, John S.; Campbell, Jason P.] Natl Inst Stand & Technol, Gaithersburg, MD 20899 USA.
[Yu, Liangchun; Sheng, Kuang] Rutgers State Univ, Piscataway, NJ 08854 USA.
[Lelis, Aivars J.] Army Res Lab, Adelphi, MD 20783 USA.
[Ryu, Sei-Hyung] Cree Inc, Durham, NC 27703 USA.
RP Cheung, KP (reprint author), Natl Inst Stand & Technol, 100 Bur Dr, Gaithersburg, MD 20899 USA.
EM liangchun.yu@nist.gov; kpckpc@ieee.org; john.suehle@nist.gov;
jason.campbell@nist.gov; ksheng@ece.rutgers.edu; alelis@arl.army.mil;
sei-hyung_ryu@cree.com
NR 4
TC 2
Z9 2
U1 2
U2 2
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 0255-5476
J9 MATER SCI FORUM
PY 2009
VL 615-617
BP 813
EP 816
PG 4
WC Engineering, Electrical & Electronic; Materials Science, Ceramics;
Materials Science, Multidisciplinary
SC Engineering; Materials Science
GA BJH84
UT WOS:000265961100197
ER
PT J
AU Pierson, JC
DiCaudo, DJ
AF Pierson, Joseph C.
DiCaudo, David J.
BE Hall, JC
Hall, BJ
TI INFECTIONS IN THE DESERT
SO SKIN INFECTIONS: DIAGNOSIS AND TREATMENT
LA English
DT Article; Book Chapter
ID CUTANEOUS LEISHMANIASIS; PULMONARY COCCIDIOIDOMYCOSIS;
CLINICAL-DIAGNOSIS; LESIONS
C1 [Pierson, Joseph C.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
[Pierson, Joseph C.] US Mil Acad, West Point, NY 10996 USA.
[DiCaudo, David J.] Mayo Clin, Dept Dermatol & Pathol, Scottsdale, AZ USA.
RP Pierson, JC (reprint author), Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
NR 27
TC 0
Z9 0
U1 0
U2 0
PU CAMBRIDGE UNIV PRESS
PI CAMBRIDGE
PA THE PITT BUILDING, TRUMPINGTON ST, CAMBRIDGE CB2 1RP, CAMBS, ENGLAND
BN 978-0-521-89729-7
PY 2009
BP 135
EP 149
PG 15
WC Dermatology; Infectious Diseases
SC Dermatology; Infectious Diseases
GA BCH85
UT WOS:000310222400013
ER
PT J
AU Andrada, T
Lettieri, C
Khramtsov, A
Holley, A
Roop, S
Patterson, H
AF Andrada, T.
Lettieri, C.
Khramtsov, A.
Holley, A.
Roop, S.
Patterson, H.
TI ACCURACY OF PRESSURE TRANSDUCER AIRFLOW FOR THE DIAGNOSIS OF UPPER
AIRWAY RESISTANCE SYNDROME
SO SLEEP
LA English
DT Meeting Abstract
CT 23rd Annual Meeting of the Associated-Professional-Sleep-Societies
CY JUN 06-11, 2009
CL Seattle, WA
SP Associated Profess Sleep Soc
C1 [Andrada, T.; Lettieri, C.; Khramtsov, A.; Holley, A.; Roop, S.; Patterson, H.] Walter Reed Army Med Ctr, Sleep Disorders Ctr, Washington, DC 20307 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER ACAD SLEEP MEDICINE
PI WESTCHESTER
PA ONE WESTBROOK CORPORATE CTR, STE 920, WESTCHESTER, IL 60154 USA
SN 0161-8105
J9 SLEEP
JI Sleep
PY 2009
VL 32
MA 1180
BP A385
EP A386
PG 2
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 438FT
UT WOS:000265542001526
ER
PT J
AU Coddington, N
Carr, W
Picchioni, D
Horovitz, SG
Fukunaga, M
Duyn, JH
Braun, AR
Balkin, TJ
AF Coddington, N.
Carr, W.
Picchioni, D.
Horovitz, S. G.
Fukunaga, M.
Duyn, J. H.
Braun, A. R.
Balkin, T. J.
TI ACTIVATION DIFFERENCES DURING ASCENDING AND DESCENDING TRENDS IN A-WAVE
POWER WHILE SLEEPING
SO SLEEP
LA English
DT Meeting Abstract
CT 23rd Annual Meeting of the Associated-Professional-Sleep-Societies
CY JUN 06-11, 2009
CL Seattle, WA
SP Associated Profess Sleep Soc
C1 [Coddington, N.] Thomas Jefferson High Sch Sci & Technol, Alexandria, VA USA.
[Coddington, N.; Carr, W.] USN, Med Res Ctr, Silver Spring, MI USA.
[Carr, W.; Picchioni, D.; Braun, A. R.] Natl Inst Deafness & Other Commun Disorders, Bethesda, MD USA.
[Picchioni, D.; Balkin, T. J.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Horovitz, S. G.; Fukunaga, M.; Duyn, J. H.] Natl Inst Neurol Disorders & Stroke, Bethesda, MD USA.
RI Duyn, Jozef/F-2483-2010
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER ACAD SLEEP MEDICINE
PI WESTCHESTER
PA ONE WESTBROOK CORPORATE CTR, STE 920, WESTCHESTER, IL 60154 USA
SN 0161-8105
J9 SLEEP
JI Sleep
PY 2009
VL 32
MA 0061
BP A20
EP A20
PG 1
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 438FT
UT WOS:000265542000063
ER
PT J
AU Collen, J
Holley, A
Lettieri, C
Shah, A
Kelly, W
Roop, S
AF Collen, J.
Holley, A.
Lettieri, C.
Shah, A.
Kelly, W.
Roop, S.
TI IMPACT OF SPLIT-NIGHT VERSUS TRADITIONAL SLEEP STUDIES ON CPAP
COMPLIANCE
SO SLEEP
LA English
DT Meeting Abstract
CT 23rd Annual Meeting of the Associated-Professional-Sleep-Societies
CY JUN 06-11, 2009
CL Seattle, WA
SP Associated Profess Sleep Soc
C1 [Collen, J.; Holley, A.; Lettieri, C.; Shah, A.; Kelly, W.; Roop, S.] Walter Reed Army Med Ctr, Washington, DC 20307 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER ACAD SLEEP MEDICINE
PI WESTCHESTER
PA ONE WESTBROOK CORPORATE CTR, STE 920, WESTCHESTER, IL 60154 USA
SN 0161-8105
J9 SLEEP
JI Sleep
PY 2009
VL 32
MA 0552
BP A181
EP A182
PG 2
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 438FT
UT WOS:000265542000554
ER
PT J
AU Eliasson, AH
Kashani, M
Lettieri, C
Vernalis, M
AF Eliasson, A. H.
Kashani, M.
Lettieri, C.
Vernalis, M.
TI CORRELATIONS BETWEEN ACTIVITY AND SLEEP
SO SLEEP
LA English
DT Meeting Abstract
CT 23rd Annual Meeting of the Associated-Professional-Sleep-Societies
CY JUN 06-11, 2009
CL Seattle, WA
SP Associated Profess Sleep Soc
C1 [Eliasson, A. H.; Kashani, M.; Vernalis, M.] Walter Reed Army Med Ctr, Integrat Cardiac Hlth Project, Washington, DC 20307 USA.
[Eliasson, A. H.; Kashani, M.; Vernalis, M.] Henry M Jackson Fdn Advancement Mil Med, Rockville, MD USA.
[Lettieri, C.] Walter Reed Army Med Ctr, Sleep Disorders Ctr, Washington, DC 20307 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER ACAD SLEEP MEDICINE
PI WESTCHESTER
PA ONE WESTBROOK CORPORATE CTR, STE 920, WESTCHESTER, IL 60154 USA
SN 0161-8105
J9 SLEEP
JI Sleep
PY 2009
VL 32
MA 1277
BP A417
EP A417
PG 1
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 438FT
UT WOS:000265542001623
ER
PT J
AU Holley, AB
Shah, A
Roop, S
Kelly, W
Lettieri, C
AF Holley, A. B.
Shah, A.
Roop, S.
Kelly, W.
Lettieri, C.
TI A PROSPECTIVE EVALUATION OF TREATMENT OUTCOMES IN MILD OSAS
SO SLEEP
LA English
DT Meeting Abstract
CT 23rd Annual Meeting of the Associated-Professional-Sleep-Societies
CY JUN 06-11, 2009
CL Seattle, WA
SP Associated Profess Sleep Soc
C1 [Holley, A. B.; Shah, A.; Roop, S.; Kelly, W.; Lettieri, C.] Walter Reed Army Med Ctr, Med Pulm Sleep & Crit Care Serv, Washington, DC 20307 USA.
[Kelly, W.] Uniformed Serv Univ Hlth Sci, Gainesville, FL USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER ACAD SLEEP MEDICINE
PI WESTCHESTER
PA ONE WESTBROOK CORPORATE CTR, STE 920, WESTCHESTER, IL 60154 USA
SN 0161-8105
J9 SLEEP
JI Sleep
PY 2009
VL 32
MA 712
BP A232
EP A232
PG 1
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 438FT
UT WOS:000265542001062
ER
PT J
AU Killgore, DB
Killgore, WD
Grugle, NL
Balkin, TJ
AF Killgore, D. B.
Killgore, W. D.
Grugle, N. L.
Balkin, T. J.
TI EXECUTIVE FUNCTIONS PREDICT THE ABILITY TO SUSTAIN PSYCHOMOTOR VIGILANCE
DURING SLEEP LOSS
SO SLEEP
LA English
DT Meeting Abstract
CT 23rd Annual Meeting of the Associated-Professional-Sleep-Societies
CY JUN 06-11, 2009
CL Seattle, WA
SP Associated Profess Sleep Soc
C1 [Killgore, D. B.; Killgore, W. D.; Grugle, N. L.; Balkin, T. J.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Killgore, W. D.] Harvard Univ, Sch Med, Belmont, MA 02178 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER ACAD SLEEP MEDICINE
PI WESTCHESTER
PA ONE WESTBROOK CORPORATE CTR, STE 920, WESTCHESTER, IL 60154 USA
SN 0161-8105
J9 SLEEP
JI Sleep
PY 2009
VL 32
MA 477
BP A158
EP A158
PG 1
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 438FT
UT WOS:000265542000479
ER
PT J
AU Killgore, WD
Killgore, DB
Kamimori, GH
Balkin, TJ
AF Killgore, W. D.
Killgore, D. B.
Kamimori, G. H.
Balkin, T. J.
TI CAFFEINE PROTECTS AGAINST INCREASED RISK-TAKING BEHAVIOR DURING SEVERE
SLEEP DEPRIVATION
SO SLEEP
LA English
DT Meeting Abstract
CT 23rd Annual Meeting of the Associated-Professional-Sleep-Societies
CY JUN 06-11, 2009
CL Seattle, WA
SP Associated Profess Sleep Soc
C1 [Killgore, W. D.; Killgore, D. B.; Kamimori, G. H.; Balkin, T. J.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Killgore, W. D.] Harvard Univ, Sch Med, Belmont, MA 02178 USA.
NR 0
TC 0
Z9 0
U1 1
U2 1
PU AMER ACAD SLEEP MEDICINE
PI WESTCHESTER
PA ONE WESTBROOK CORPORATE CTR, STE 920, WESTCHESTER, IL 60154 USA
SN 0161-8105
J9 SLEEP
JI Sleep
PY 2009
VL 32
MA 0473
BP A156
EP A157
PG 2
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 438FT
UT WOS:000265542000475
ER
PT J
AU Picchioni, D
Horovitz, SG
Fukunaga, M
Carr, WS
Balkin, TJ
Duyn, JH
Braun, AR
AF Picchioni, D.
Horovitz, S. G.
Fukunaga, M.
Carr, W. S.
Balkin, T. J.
Duyn, J. H.
Braun, A. R.
TI HOW SLOW CAN YOU GO? UNIQUE FMRI CORRELATIONS WITH EEG ACTIVITY BELOW
0.1 HZ DURING SLEEP
SO SLEEP
LA English
DT Meeting Abstract
CT 23rd Annual Meeting of the Associated-Professional-Sleep-Societies
CY JUN 06-11, 2009
CL Seattle, WA
SP Associated Profess Sleep Soc
C1 [Picchioni, D.; Balkin, T. J.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Horovitz, S. G.; Fukunaga, M.; Duyn, J. H.; Braun, A. R.] NIH, Bethesda, MD 20892 USA.
[Carr, W. S.] USN, Med Res Ctr, Silver Spring, MD USA.
RI Duyn, Jozef/F-2483-2010; Fukunaga, Masaki/F-6441-2013
OI Fukunaga, Masaki/0000-0003-1010-2644
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER ACAD SLEEP MEDICINE
PI WESTCHESTER
PA ONE WESTBROOK CORPORATE CTR, STE 920, WESTCHESTER, IL 60154 USA
SN 0161-8105
J9 SLEEP
JI Sleep
PY 2009
VL 32
MA 0033
BP A11
EP A11
PG 1
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 438FT
UT WOS:000265542000035
ER
PT J
AU Russo, M
Stetz, M
Stetz, T
AF Russo, M.
Stetz, M.
Stetz, T.
TI THE PREVALENCE OF SLEEP/WAKE DISTURBANCES IN MILD TRAUMATIC BRAIN INJURY
PATIENTS
SO SLEEP
LA English
DT Meeting Abstract
CT 23rd Annual Meeting of the Associated-Professional-Sleep-Societies
CY JUN 06-11, 2009
CL Seattle, WA
SP Associated Profess Sleep Soc
C1 [Russo, M.] Tripler Army Med Ctr, Tripler, HI USA.
[Russo, M.] Univ Hawaii, Sch Med, Dept Med, Honolulu, HI 96822 USA.
[Russo, M.] Uniformed Serv Univ Hlth Sci, Sch Med, Dept Neurol, Bethesda, MD USA.
[Stetz, T.] Natl Geospatial Intelligence Agcy, Honolulu, HI USA.
[Stetz, M.] Tripler Army Med Ctr, Honolulu, HI 96859 USA.
RI Sanguansri, Luz/B-6630-2011
OI Sanguansri, Luz/0000-0003-1908-7604
NR 0
TC 0
Z9 0
U1 1
U2 1
PU AMER ACAD SLEEP MEDICINE
PI WESTCHESTER
PA ONE WESTBROOK CORPORATE CTR, STE 920, WESTCHESTER, IL 60154 USA
SN 0161-8105
J9 SLEEP
JI Sleep
PY 2009
VL 32
SU S
MA 0954
BP A311
EP A311
PG 1
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 438FT
UT WOS:000265542001301
ER
PT J
AU Russo, M
Stetz, M
Swanson, E
Stetz, T
AF Russo, M.
Stetz, M.
Swanson, E.
Stetz, T.
TI EXCESSIVE DAYTIME SLEEPINESS IN MILD TRAUMATIC BRAIN INJURY (MTBI)
PATIENTS
SO SLEEP
LA English
DT Meeting Abstract
CT 23rd Annual Meeting of the Associated-Professional-Sleep-Societies
CY JUN 06-11, 2009
CL Seattle, WA
SP Associated Profess Sleep Soc
C1 [Russo, M.; Swanson, E.] Tripler Army Med Ctr, Tripler, HI USA.
[Russo, M.] Univ Hawaii, Sch Med, Honolulu, HI 96822 USA.
[Russo, M.] USUHS Sch Med, Dept Neurol, Bethesda, MD USA.
[Stetz, M.] Tripler Army Med Ctr, Honolulu, HI 96859 USA.
[Stetz, T.] Natl Geospatial Intelligence Agcy, Honolulu, HI USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER ACAD SLEEP MEDICINE
PI WESTCHESTER
PA ONE WESTBROOK CORPORATE CTR, STE 920, WESTCHESTER, IL 60154 USA
SN 0161-8105
J9 SLEEP
JI Sleep
PY 2009
VL 32
SU S
MA 0955
BP A311
EP A311
PG 1
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 438FT
UT WOS:000265542001302
ER
PT J
AU Shah, A
Lettieri, C
Holley, A
Kelly, W
Roop, S
AF Shah, A.
Lettieri, C.
Holley, A.
Kelly, W.
Roop, S.
TI ESZOPICLONE IMPROVES SHORT AND INTERMEDIATE TERM CONTINUOUS POSITIVE
AIRWAY PRESSURE COMPLIANCE
SO SLEEP
LA English
DT Meeting Abstract
CT 23rd Annual Meeting of the Associated-Professional-Sleep-Societies
CY JUN 06-11, 2009
CL Seattle, WA
SP Associated Profess Sleep Soc
C1 [Shah, A.; Lettieri, C.; Holley, A.; Kelly, W.; Roop, S.] Walter Reed Army Med Ctr, Washington, DC 20307 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER ACAD SLEEP MEDICINE
PI WESTCHESTER
PA ONE WESTBROOK CORPORATE CTR, STE 920, WESTCHESTER, IL 60154 USA
SN 0161-8105
J9 SLEEP
JI Sleep
PY 2009
VL 32
MA 0561
BP A184
EP A185
PG 2
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 438FT
UT WOS:000265542000563
ER
PT J
AU Stetz, A
Russo, M
Stetz, T
AF Stetz, A.
Russo, M.
Stetz, T.
TI A SLEEP SCREENING TOOL FOR MILITARY PERSONNEL: THE POST TRAUMATIC STRESS
DISORDER CHECKLIST
SO SLEEP
LA English
DT Meeting Abstract
CT 23rd Annual Meeting of the Associated-Professional-Sleep-Societies
CY JUN 06-11, 2009
CL Seattle, WA
SP Associated Profess Sleep Soc
C1 [Stetz, A.] Tripler Army Med Ctr, Tripler, HI USA.
[Stetz, T.] Natl Geospatial Intelligence Agcy, Honolulu, HI USA.
[Russo, M.] Univ Hawaii, Sch Med, Honolulu, HI 96822 USA.
[Russo, M.] USUHS Sch Med, Bethesda, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER ACAD SLEEP MEDICINE
PI WESTCHESTER
PA ONE WESTBROOK CORPORATE CTR, STE 920, WESTCHESTER, IL 60154 USA
SN 0161-8105
J9 SLEEP
JI Sleep
PY 2009
VL 32
MA 1087
BP A354
EP A355
PG 2
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 438FT
UT WOS:000265542001434
ER
PT J
AU Stetz, M
Stetz, T
Cuff, P
Russo, M
AF Stetz, M.
Stetz, T.
Cuff, P.
Russo, M.
TI INSOMNIA IN MILD TRAUMATIC BRAIN INJURY (MTBI) PATIENTS
SO SLEEP
LA English
DT Meeting Abstract
CT 23rd Annual Meeting of the Associated-Professional-Sleep-Societies
CY JUN 06-11, 2009
CL Seattle, WA
SP Associated Profess Sleep Soc
C1 [Russo, M.] Tripler Army Med Ctr, Tripler, HI USA.
[Russo, M.] Univ Hawaii, Dept Med, Sch Med, Honolulu, HI 96822 USA.
[Russo, M.] USUHS Dept Neurol, Dept Neurol, Bethesda, MD USA.
[Stetz, T.] Natl Geospatial Intelligence Agcy, Honolulu, HI USA.
[Stetz, M.; Cuff, P.] Tripler Army Med Ctr, Honolulu, HI 96859 USA.
NR 0
TC 1
Z9 1
U1 0
U2 0
PU AMER ACAD SLEEP MEDICINE
PI WESTCHESTER
PA ONE WESTBROOK CORPORATE CTR, STE 920, WESTCHESTER, IL 60154 USA
SN 0161-8105
J9 SLEEP
JI Sleep
PY 2009
VL 32
MA 952
BP A310
EP A310
PG 1
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 438FT
UT WOS:000265542001299
ER
PT J
AU Torch, W
Cardillo, C
Russo, M
Publicover, N
Gutierrez, E
McMullen, S
Martin, M
Parseghian, Z
AF Torch, W.
Cardillo, C.
Russo, M.
Publicover, N.
Gutierrez, E.
McMullen, S.
Martin, M.
Parseghian, Z.
TI OCULOMETRIC INDICES ASSOCIATED WITH DROWSINESS AND PERFORMANCE VIGILANCE
IMPAIRMENT IN SLEEP-DEPRIVED NORMAL, SLEEP APNEA, NARCOLEPSY AND
ADD/ADHD SUBJECTS
SO SLEEP
LA English
DT Meeting Abstract
CT 23rd Annual Meeting of the Associated-Professional-Sleep-Societies
CY JUN 06-11, 2009
CL Seattle, WA
SP Associated Profess Sleep Soc
C1 [Torch, W.; Cardillo, C.; Publicover, N.; Gutierrez, E.; McMullen, S.; Parseghian, Z.] Eye Com Corp, Reno, NV USA.
[Torch, W.; Gutierrez, E.; Martin, M.] Washoe Sleep Disorders Ctr, Reno, NV USA.
[Russo, M.] Tripler Army Med Ctr, Honolulu, HI 96859 USA.
[Publicover, N.] Univ Nevada, Reno, NV 89557 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER ACAD SLEEP MEDICINE
PI WESTCHESTER
PA ONE WESTBROOK CORPORATE CTR, STE 920, WESTCHESTER, IL 60154 USA
SN 0161-8105
J9 SLEEP
JI Sleep
PY 2009
VL 32
MA 0406
BP A134
EP A135
PG 2
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 438FT
UT WOS:000265542000408
ER
PT S
AU Currano, LJ
Gee, D
Churaman, W
Dubey, M
Amirtharaj, P
Yu, M
Balachandran, B
AF Currano, Luke J.
Gee, Danny
Churaman, Wayne
Dubey, Madan
Amirtharaj, Paul
Yu, Miao
Balachandran, Balakumar
BE Vincenzini, P
Darrigo, G
TI MEMS Rotational Actuator for High Force and Large Displacement
SO SMART MATERIALS & MICRO/NANOSYSTEMS
SE Advances in Science and Technology
LA English
DT Proceedings Paper
CT 3rd International Conference on Smart Materials, Structures and Systems
CY JUN 08-13, 2008
CL Acireale, ITALY
DE MEMS; actuator; thermal; rotation; rotary; torsion; in-plane
ID THERMAL ACTUATORS; DESIGN
AB A MEMS thermal actuator that provides rotational or near-linear translational displacements is investigated. This actuator provides a solution to applications that require high-forces and large displacements. Output moments up to 7x10(-7) N-m and free rotations of up to 3 degrees were measured. These correspond to forces of up to 1.44mN at a displacement of 23.7 mu m, yielding a work of 3.41 x 10(-8) N-m. An electrothermal-mechanical model that considers temperature dependence of material properties is presented, and the model predictions show good agreement with actuator test data.
C1 [Currano, Luke J.; Gee, Danny; Churaman, Wayne; Dubey, Madan; Amirtharaj, Paul; Yu, Miao; Balachandran, Balakumar] USA, Res Lab, Adelphi, MD 20783 USA.
RP Currano, LJ (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM lcurrano@arl.army.mil; danny.gee@arl.army.mil;
wayne.churaman@arl.army.mil; mdubey@arl.army.mil;
pamirtharaj@arl.army.mil; mmyu@umd.edu; balab@umd.edu
NR 15
TC 0
Z9 0
U1 1
U2 3
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 1662-0356
BN 978-3-908158-20-2
J9 ADV SCI TECH
PY 2009
VL 54
BP 372
EP 377
PG 6
WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary
SC Science & Technology - Other Topics; Materials Science
GA BJD42
UT WOS:000265012100056
ER
PT S
AU Churaman, WA
Currano, L
Gee, D
Zakar, E
AF Churaman, Wayne A.
Currano, Luke
Gee, Danny
Zakar, Eugene
BE Vincenzini, P
Darrigo, G
TI Three-Axis MEMS Threshold Accelerometer Switch for Enhanced Power
Conservation of MEMS Sensors
SO SMART MATERIALS & MICRO/NANOSYSTEMS
SE Advances in Science and Technology
LA English
DT Proceedings Paper
CT 3rd International Conference on Smart Materials, Structures and Systems
CY JUN 08-13, 2008
CL Acireale, ITALY
DE MEMS; accelerometers; threshold; switch; sensor; 3-axis
ID DESIGN
AB A no-power 3-axis bidirectional MEMS threshold accelerometer is presented in this paper. Threshold accelerometers of 25g, 50g, and 100g were designed and fabricated on a single 3mm chip. The design is based on a conductive spring-mass system made of Au metal layers that close a switch between two metal contacts when the designed threshold is exceeded. We present the MEMS threshold accelerometer switch fabrication process and provide an analytical and experimental framework for the device performance
C1 [Churaman, Wayne A.; Currano, Luke; Gee, Danny; Zakar, Eugene] USA, Res Lab, Adelphi, MD 20783 USA.
RP Churaman, WA (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM wayne.churaman@arl.army.mil; lcurrano@arl.army.mil;
danny.gee@arl.army.mil; ezakar@arl.army.mil
NR 5
TC 0
Z9 0
U1 2
U2 2
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 1662-0356
BN 978-3-908158-20-2
J9 ADV SCI TECH
PY 2009
VL 54
BP 384
EP 389
PG 6
WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary
SC Science & Technology - Other Topics; Materials Science
GA BJD42
UT WOS:000265012100058
ER
PT S
AU Pellegrino, JM
AF Pellegrino, John M.
BE Vincenzini, P
Darrigo, G
TI The Promise of Nano and Micro Systems for Meeting the Emerging Demands
of the US Army
SO SMART MATERIALS & MICRO/NANOSYSTEMS
SE Advances in Science and Technology
LA English
DT Proceedings Paper
CT 3rd International Conference on Smart Materials, Structures and Systems
CY JUN 08-13, 2008
CL Acireale, ITALY
DE Sensors; MEMS; PZT; nanostrucutres
ID FILM PIEZOELECTRIC ACTUATORS
AB The rapidly changing defense landscape and the exponential increase in complex challenges and threats faced by our warfighters demand revolutionary advances across the spectrum and even a rethinking of current combat doctrine. Sensors and Electron devices are critical elements in a number of application form providing situational awareness to battlefield operations. Enabling nano and micro system approaches offer the potential to fulfill Army needs in applications such as chemical and biological sensors, high-frequency and low-power electronics, micro autonomous systems, micro power generation, specialized optical sources and detectors and much more. A large part of the advances thus far originate in insights and understanding of the underlying materials. I will review some emerging needs with recent illustrative examples from the field and will follow up with potential solutions that are being developed within ARL and our Army partners. These include RF MEMS for electronically scanned antennas, carbon nanotube and other nanostructure based chemical/biological sensors, biomimetic approaches to materials development for power storage applications and nanostructured semiconductors for integrated electronics and energetics.
C1 USA, Res Lab, Adelphi, MD USA.
RP Pellegrino, JM (reprint author), USA, Res Lab, Adelphi, MD USA.
EM john.m.pellegrino@us.army.mil
NR 8
TC 0
Z9 0
U1 1
U2 4
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 1662-0356
BN 978-3-908158-20-2
J9 ADV SCI TECH
PY 2009
VL 54
BP 396
EP 400
PG 5
WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary
SC Science & Technology - Other Topics; Materials Science
GA BJD42
UT WOS:000265012100060
ER
PT S
AU Zakar, E
Wikner, D
Dubey, M
Amirtharaj, P
AF Zakar, E.
Wikner, D.
Dubey, M.
Amirtharaj, Paul
BE Vincenzini, P
Darrigo, G
TI Thin Film YBCO Pixels for MMW Detector
SO SMART MATERIALS & MICRO/NANOSYSTEMS
SE Advances in Science and Technology
LA English
DT Proceedings Paper
CT 3rd International Conference on Smart Materials, Structures and Systems
CY JUN 08-13, 2008
CL Acireale, ITALY
DE YBCO; etch; MMW; sensor
ID BOLOMETERS; SILICON
AB This research addresses the fabrication of crack-free 40-nm thin film YBa(2)Cu(3)O(7) (YBCO) Pixel structures based on high temperature superconductor (HTSC) microbolometers for highly sensitive thermal detectors that can be miniaturized for affordable passive millimeter-wave (MMW) imaging. A completely dry etch process is described for suspended transition edge bolometers by removing (releasing) the silicon substrate underneath a 3 micrometer wide pixel using gaseous plasma sulfurhexafluoride (SF(6)) chemical reaction. This is an improvement over conventional selective wet chemical etching techniques that are both harsh on the YBCO and require additional complex alignment steps to the substrate material leading to very poor device yields and performance. Issues relating to material roughness, etch redeposition, and silicon undercutting will be analyzed and methodologies to overcome/minimize such problems will be explained in detail.
C1 [Zakar, E.; Wikner, D.; Dubey, M.; Amirtharaj, Paul] USA, Res Lab, Adelphi, MD 20783 USA.
RP Zakar, E (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM ezakar@arl.army.mil; dwikner@arl.army.mil; mdubey@arl.army.mil;
pamirtharaj@arl.army.mil
NR 9
TC 0
Z9 0
U1 0
U2 0
PU TRANS TECH PUBLICATIONS LTD
PI STAFA-ZURICH
PA LAUBLSRUTISTR 24, CH-8717 STAFA-ZURICH, SWITZERLAND
SN 1662-0356
BN 978-3-908158-20-2
J9 ADV SCI TECH
PY 2009
VL 54
BP 434
EP 438
PG 5
WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary
SC Science & Technology - Other Topics; Materials Science
GA BJD42
UT WOS:000265012100067
ER
PT B
AU Snyder, JF
O'Brien, DJ
Baechle, DM
Mattson, DE
Wetzel, ED
AF Snyder, James F.
O'Brien, Daniel J.
Baechle, Daniel M.
Mattson, Daniel E.
Wetzel, Eric D.
GP ASME
TI STRUCTURAL COMPOSITE CAPACITORS, SUPERCAPACITORS, AND BATTERIES FOR US
ARMY APPLICATIONS
SO SMASIS2008: PROCEEDINGS OF THE ASME CONFERENCE ON SMART MATERIALS,
ADAPTIVE STRUCTURES AND INTELLIGENT SYSTEMS - 2008, VOL 1
LA English
DT Proceedings Paper
CT Conference on Smart Materials, Adaptive Structures and Intelligent
Systems
CY OCT 28-30, 2008
CL Ellicot, MD
SP ASME, Nanotechnol Inst
ID DIELECTRIC-PROPERTIES; SYSTEMS; DESIGN
AB Structural capacitors, supercapacitors, and batteries are fabricated and tested, using modified materials and processes based on conventional fiber-reinforced polymer matrix composites. Printed circuit board prepregs are used to create structural capacitors that demonstrate good dielectric energy density and mechanical stiffness and strength. Structural supercapacitors are created using carbon fabric electrodes and a liquid-plasticized, epoxy polymer electrolyte. A similar construction is used to create structural batteries, by substituting LiFePO(4)-coated carbon fiber fabric as cathodes opposed to unmodified carbon fiber anodes. Structural batteries and supercapacitors show basic electrochemical and mechanical functionality. However, significant additional work is required to improve their quantitative performance to values of practical engineering value.
C1 [Snyder, James F.; O'Brien, Daniel J.; Baechle, Daniel M.; Wetzel, Eric D.] USA, Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA.
RP Snyder, JF (reprint author), USA, Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA.
NR 25
TC 0
Z9 0
U1 2
U2 5
PU AMER SOC MECHANICAL ENGINEERS
PI NEW YORK
PA THREE PARK AVENUE, NEW YORK, NY 10016-5990 USA
BN 978-0-7918-4331-4
PY 2009
BP 1
EP 8
PG 8
WC Computer Science, Artificial Intelligence; Engineering, Mechanical;
Materials Science, Multidisciplinary
SC Computer Science; Engineering; Materials Science
GA BJE63
UT WOS:000265211900001
ER
PT J
AU Castro, CC
AF Castro, Colonel Carl
TI Impact of Combat on the Mental Health and Well-Being of Soldiers and
Marines
SO SMITH COLLEGE STUDIES IN SOCIAL WORK
LA English
DT Article
DE PTSD; Battlemind Training; DSM-IVTR; Combat exposure; risks
AB This presentation introduces a summary of leading edge research and recommendations for a number of changes regarding mental health needs and services for Veterans. Those Veterans who experienced combat exposure and those who have perceived their leadership negatively have greater risks for developing subsequent PTSD. Research data provide support for the use of Battlemind Training as a useful approach to prevent mental health issues at all phases of the deployment cycle. The author also challenges the current use of DSM-IVTR diagnoses with combat Veterans.
C1 USA, Mil Operat Med Res Program, Med Res & Mat Command, Ft Detrick, MD 21702 USA.
RP Castro, CC (reprint author), USA, Mil Operat Med Res Program, Med Res & Mat Command, Ft Detrick, MD 21702 USA.
EM castro.carl1@gmail.com
NR 4
TC 5
Z9 5
U1 1
U2 4
PU HAWORTH PRESS INC
PI BINGHAMTON
PA 10 ALICE ST, BINGHAMTON, NY 13904-1580 USA
SN 0037-7317
J9 SMITH COLL STUD SOC
JI Smith Coll. Stud. Soc. Work
PY 2009
VL 79
IS 3-4
BP 247
EP 262
AR PII 916163794
DI 10.1080/00377310903130290
PG 16
WC Social Work
SC Social Work
GA 524IL
UT WOS:000272136900002
ER
PT J
AU Leiner, B
AF Leiner, Barbara
TI The Legacy of War: An Intergenerational Perspective
SO SMITH COLLEGE STUDIES IN SOCIAL WORK
LA English
DT Article
DE Veterans; combat trauma; intergenerational effects; family relationships
ID CHILDREN; VETERANS; HOLOCAUST; SURVIVORS
AB Children of combat veterans are affected to varying extents by the physical and psychological aftermath of war as experienced by the parent. Traumatic experiences exist on a continuum; trauma related messages can be communicated by a parent who does not have Post Traumatic Stress Disorder. An intergenerational perspective explores the complex family processes by which those who did not experience the actual events come to exhibit varying degress of emotional, psychological and behavioral manifestations of their parents' traumatic experiences.
C1 Walter Reed Army Med Ctr, Child & Adolescent Psychiat Serv, LCSW C, Washington, DC 20307 USA.
RP Leiner, B (reprint author), Walter Reed Army Med Ctr, Child & Adolescent Psychiat Serv, LCSW C, 6900 Georgia Ave NW, Washington, DC 20307 USA.
EM BARBARA.LEINER@US.ARMY.MIL
NR 16
TC 2
Z9 2
U1 0
U2 4
PU HAWORTH PRESS INC
PI BINGHAMTON
PA 10 ALICE ST, BINGHAMTON, NY 13904-1580 USA
SN 0037-7317
J9 SMITH COLL STUD SOC
JI Smith Coll. Stud. Soc. Work
PY 2009
VL 79
IS 3-4
BP 375
EP 391
AR PII 916163815
DI 10.1080/00377310903249884
PG 17
WC Social Work
SC Social Work
GA 524IL
UT WOS:000272136900013
ER
PT J
AU Grace, JK
Yamamoto, RT
AF Grace, J. Kenneth
Yamamoto, Robin T.
TI Food Utilization and Fecal Pellet Production by Drywood Termites
(Isoptera: Kalotermitidae)
SO SOCIOBIOLOGY
LA English
DT Article
ID CRYPTOTERMES-BREVIS ISOPTERA
AB Cryptotermes brevis (Walker) and Incisitermes immigrans (Light) nymphs were held either individually or in groups of ten for an eight-week period, and fed either filter paper, Douglas-fir, or Ponderosapine. Total consumption was noted; and fecal pellet number, mass, and volume were recorded weekly. Solitary individuals defecated more and produced smaller fecal pellets than nymphs maintained in groups, although the total individual mass of feces produced was similar. Diet affected feeding, food utilization, and fecal pellet number and mass. Consumption and defecation reflected cellulose and lignin content of the substrate, with less ingestion of filter paper than wood on a weight basis, but greater utilization of the ingested paper (98%) and less fecal mass. The percentages of the ingested wood utilized (not excreted) were virtually equivalent for Douglas-fir and pine: 63% and 65%, respectively, with C. brevis, and 71% and 72% with I. immigrans. Each I. immigrans nymph consumed about 0.2 mg of wood each day, while each C. brevis nymph consumed slightly less than 0.15 mg of wood per day. On the average, nymphs of both termite species deposited from 0.7 to 1.0 fecal pellets per day, equivalent to a daily average fecal mass of 0.06 mg when fed Douglas-fir, and 0.05 mg when fed pine. Correlation of these data with population growth curves could permit estimation of the size and age of drywood termite colonies.
C1 [Grace, J. Kenneth] Univ Hawaii Manoa, Dept Plant & Environm Protect Sci, Honolulu, HI 96822 USA.
[Yamamoto, Robin T.] US Army Garrison Hawaii, Environm Div, Directorate Publ Works, Schofield Barracks, HI 96857 USA.
RP Grace, JK (reprint author), Univ Hawaii Manoa, Dept Plant & Environm Protect Sci, 3050 Maile Way, Honolulu, HI 96822 USA.
EM kennethg@hawaii.edu; robin.yamamoto@us.army.mil
FU USDA-ARS Specific Cooperative Agreement [58-6615-4-237]; College of
Tropical Agriculture and Human Resources, University of Hawaii at Mano
FX This research was supported by USDA-ARS Specific Cooperative Agreement
58-6615-4-237, and McIntire-Stennis funds for forestry research
administered by the College of Tropical Agriculture and Human Resources,
University of Hawaii at Manoa.
NR 10
TC 4
Z9 4
U1 1
U2 2
PU CALIFORNIA STATE UNIV
PI CHICO
PA DEPT BIOL SCI, CHICO, CA 95929 USA
SN 0361-6525
J9 SOCIOBIOLOGY
JI Sociobiology
PY 2009
VL 53
IS 3
BP 903
EP 911
PG 9
WC Entomology
SC Entomology
GA 507NI
UT WOS:000270860800022
ER
PT J
AU Clausen, J
Korte, N
AF Clausen, Jay
Korte, Nic
TI The Distribution of Metals in Soils and Pore Water at Three US Military
Training Facilities
SO SOIL & SEDIMENT CONTAMINATION
LA English
DT Article
DE antimony; copper; lead; pore-water sampling; soil contamination; zinc
ID SHOOTING RANGE SOIL; TRACE-METALS; LEAD SHOT; SPECIATION; CONTAMINATION;
SPECTROSCOPY; BULLETS
AB Small arms firing ranges at military training facilities can have enormous heavy metal burdens (percent level) in soils. Currently there are few published works that quantify the metal content of soils and waters at military installations or speculate on the potential for migration of these contaminants into groundwater. This article documents metals in soils and waters at nine small arms training ranges at three military installations in the U. S. Soil samples were collected from the surface and shallow subsurface. The results demonstrated that lead, antimony, copper, and zinc were the principal contaminants of interest and mapping a site's lead and copper surface distributions would adequately define the extent of impacted soil. Lower metal concentrations at three of the ranges reflected previous remediation by means of physical separation and mechanical removal of metallic fragments followed by fixation treatment with Maectite (TM). Except for the treated ranges where mixing had occurred, subsurface soil samples indicated limited vertical migration. Several of the ranges were also monitored for trace element migration in the vadose zone by means of suction-cup lysimeters. This pore-water sampling indicated ceramic suction-cup lysimeters are useful for assessing relative concentrations but require care in evaluation because of potential sorption losses. Monitoring of soil water at ranges should include antimony and zinc; the former because, in contrast to the other metals, it is typically soluble in an anionic form, and the latter because of its greater solubility and mobility.
C1 [Clausen, Jay] ERDC CRREL, Hanover, NH 03755 USA.
RP Clausen, J (reprint author), ERDC CRREL, 72 Lyme Rd, Hanover, NH 03755 USA.
EM Jay.L.Clausen@erdc.usace.army.mil
NR 34
TC 21
Z9 22
U1 1
U2 18
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
SN 1532-0383
J9 SOIL SEDIMENT CONTAM
JI Soil. Sediment. Contam.
PY 2009
VL 18
IS 5
BP 546
EP 563
DI 10.1080/15320380903085683
PG 18
WC Environmental Sciences
SC Environmental Sciences & Ecology
GA 495XJ
UT WOS:000269928600002
ER
PT J
AU Lehman, RA
Helgeson, MD
Keeler, KA
Bunmaprasert, T
Riew, KD
AF Lehman, Ronald A., Jr.
Helgeson, Melvin D.
Keeler, Kathryn A.
Bunmaprasert, Torphong
Riew, K Daniel
TI Comparison of Magnetic Resonance Imaging and Computed Tomography in
Predicting Facet Arthrosis in the Cervical Spine
SO SPINE
LA English
DT Article
DE cervical disc arthroplasty; disc replacement; facet joint anklyosis;
cervical spine imaging; MRI
ID CT MYELOGRAPHY; OSTEOARTHRITIS; JOINTS; MR
AB Study Design. Retrospective review.
Objective. To determine the ability of magnetic resonance imaging (MRI) and computed tomography (CT) to predict the presence of cervical facet arthrosis.
Summary of Background Data. In the Food and Drug Administration Investigational Device Exemption trials of cervical disc arthroplasty (CDA), the presence of facet arthrosis on CT was a contraindication to the insertion of a CDA. Most surgeons routinely obtain an MRI, but not necessarily a CT before performing surgery in the cervical spine. We sought to determine if the MRI alone is adequate to assess for the presence of facet arthrosis.
Methods. Three experienced spine surgeons retrospectively evaluated CT scans and MRIs of the same patients, obtained within 30 days of each other in a blinded, random fashion. Reviewers graded each of the MRI and CT scan as normal or abnormal on 3 separate occasions and if the facet was abnormal, each reviewer graded the degree of arthrosis. The radiologist's evaluation for each study was compared with our results.
Results. Of 594 facets analyzed, 43.1% were categorized as normal on CT, and of those, MRI concordance was only 63.7% with moderate/substantial intermethod agreement. Furthermore, MRI was concordant only 15.9% of the time in patients with ankylosed facet joints on CT. CT inter-rater reliability showed substantial agreement for diagnoses of both normal and ankylosis and fair agreement for lesser degrees of facet arthrosis. MRI inter-rater reliability showed fair/moderate agreement in normal and ankylosed segments and only slight agreement with lesser degrees of facet arthrosis. CT intrarater reliability showed substantial agreement in normal or ankylosed joints, but only fair agreement for all other categories; MRI showed only fair agreement.
Conclusion. The ability of MRI to adequately determine the presence or amount of facet arthrosis is not reliable. Additionally, for abnormal facets, MRI was not reliable in adequately determining the degree of arthrosis. Our data suggest that computed tomography remains necessary in diagnosing facet arthrosis before CDA.
C1 [Lehman, Ronald A., Jr.; Helgeson, Melvin D.] Walter Reed Army Med Ctr, Dept Orthopaed & Rehabil, Washington, DC 20307 USA.
[Keeler, Kathryn A.; Riew, K Daniel] Washington Univ, Sch Med, Dept Orthopaed Surg, St Louis, MO USA.
[Bunmaprasert, Torphong] Chiang Mai Univ, Dept Orthopaed, Fac Med, Chiang Mai, Thailand.
RP Lehman, RA (reprint author), Walter Reed Army Med Ctr, Dept Orthopaed & Rehabil, Washington, DC 20307 USA.
EM armyspine@yahoo.com
NR 10
TC 10
Z9 10
U1 0
U2 6
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0362-2436
J9 SPINE
JI SPINE
PD JAN 1
PY 2009
VL 34
IS 1
BP 65
EP 68
DI 10.1097/BRS.0b013e3181919526
PG 4
WC Clinical Neurology; Orthopedics
SC Neurosciences & Neurology; Orthopedics
GA 405YV
UT WOS:000263261000011
PM 19127162
ER
PT S
AU LeSueur, KG
Jovanov, E
AF LeSueur, Kenneth G.
Jovanov, Emil
GP IEEE
TI Performance Analysis of the Augmented Wireless Sensor Network Testbed
SO SSST: 2009 41ST SOUTHEASTERN SYMPOSIUM ON SYSTEM THEORY
SE Southeastern Symposium on System Theory
LA English
DT Proceedings Paper
CT 41st Southeastern Symposium on System Theory
CY MAR 15-17, 2009
CL Tullahoma, TN
DE Modeling & Simulation; Wireless Systems; Network & Communications
AB Existing testing systems are not suited for testing of tactical hardware in complex battlefield configurations due to the increased complexity of sensors that include network interfaces and sensor fusion algorithms. We are developing a system for augmented testing of wireless sensor networks that supports virtual system configurations interacting with the real-time hardware in the loop. The testbed provides a realistic simulated representation of a tactical network that allows faithful testing of networked systems focusing on hardware in the loop sensors and sensor fusion systems. Systems can be tested using this method in a controlled repeatable environment not feasible in field testing. The system design combines dedicated High Performance Computing (HPC) resources with a scalable, high fidelity network emulation and a Computer Generated Forces (CGF) model to virtually represent the tactical network, force movement, interactions, and communication loads to systems under test. The system is implemented using QualNet network emulation and OneSAF CGF running on a parallel Linux blade system and integrates sensors to the simulated virtual environment through wireless gateways and Ethernet connections. This paper presents the design framework, current implementation of the system, and real-time performance measurements.
C1 [LeSueur, Kenneth G.] USA, Redstone Tech Test Ctr, Subsyst Test & Anal Branch, Redstone Arsenal, AL 35898 USA.
[Jovanov, Emil] Univ Alabama, Dept Elect & Comp Engn, Huntsville, AL 35899 USA.
RP LeSueur, KG (reprint author), USA, Redstone Tech Test Ctr, Subsyst Test & Anal Branch, Redstone Arsenal, AL 35898 USA.
EM Ken.lesueur@us.army.mil; jovanov@ece.uah.edu
OI Jovanov, Emil/0000-0001-6754-3518
NR 5
TC 0
Z9 0
U1 0
U2 0
PU IEEE
PI NEW YORK
PA 345 E 47TH ST, NEW YORK, NY 10017 USA
SN 0094-2898
BN 978-1-4244-3324-7
J9 SE SYM SYS THRY
PY 2009
BP 319
EP +
DI 10.1109/SSST.2009.4806836
PG 2
WC Computer Science, Artificial Intelligence; Computer Science, Hardware &
Architecture; Computer Science, Theory & Methods; Robotics
SC Computer Science; Robotics
GA BKN37
UT WOS:000268672400064
ER
PT J
AU Hromadka, T
Whitley, R
Horton, S
Smith, M
Lindquist, J
AF Hromadka, T. V., II
Whitley, R. J.
Horton, S. B.
Smith, M. J.
Lindquist, J. M.
TI Generous statistical tests
SO STOCHASTIC ENVIRONMENTAL RESEARCH AND RISK ASSESSMENT
LA English
DT Article
DE Testing unlikely events; Extreme deviations; PCB contamination
AB A common statistical problem is deciding which of two possible sources, A and B, of a contaminant is most likely the actual source. The situation considered here, based on an actual problem of polychlorinated biphenyl contamination discussed below, is one in which the data strongly supports the hypothesis that source A is responsible. The problem approach here is twofold: One, accurately estimating this extreme probability. Two, since the statistics involved will be used in a legal setting, estimating the extreme probability in such a way as to be as generous as is possible toward the defendant's claim that the other site B could be responsible; thereby leaving little room for argument when this assertion is shown to be highly unlikely. The statistical testing for this problem is modeled by random variables {X (i) } and the corresponding sample mean for a given number a (0). Under the hypothesis that the random variables {X (i) } satisfy E(X (i) ) mu, for some 0 < mu < 1, statistical tests are given, described as "generous", because is maximized. The intent is to be able to reject the hypothesis that a (0) is a value of the sample mean while eliminating any possible objections to the model distributions chosen for the {X (i) } by choosing those distributions which maximize the value of for the test used.
C1 [Hromadka, T. V., II; Horton, S. B.; Smith, M. J.; Lindquist, J. M.] US Mil Acad, Dept Math Sci, West Point, NY 10096 USA.
RP Whitley, R (reprint author), POB 11133, Bainbridge Isl, WA 98110 USA.
EM ted@phdphdphd.com; rwhitley@math.uci.edu; steve.horton@usma.edu;
Mick.Smith@usma.edu; aj0558@usma.edu
NR 5
TC 1
Z9 1
U1 0
U2 1
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1436-3240
J9 STOCH ENV RES RISK A
JI Stoch. Environ. Res. Risk Assess.
PD JAN
PY 2009
VL 23
IS 1
BP 9
EP 12
DI 10.1007/s00477-007-0190-6
PG 4
WC Engineering, Environmental; Engineering, Civil; Environmental Sciences;
Statistics & Probability; Water Resources
SC Engineering; Environmental Sciences & Ecology; Mathematics; Water
Resources
GA 371UR
UT WOS:000260857400002
ER
PT B
AU Macik-Frey, M
Quick, JC
Shinoda, P
Mack, DA
Gray, DA
Keller, N
Cooper, CL
AF Macik-Frey, Marilyn
Quick, James Campbell
Shinoda, Phillip
Mack, David A.
Gray, David A.
Keller, Nathan
Cooper, Cary L.
BE Rossi, AM
Quick, JC
Perrewe, PL
TI LEADERSHIP FROM A POSITIVE HEALTH PERSPECTIVE A Qualitative Study
SO STRESS AND QUALITY OF WORKING LIFE: THE POSITIVE AND THE NEGATIVE
SE Stress and Quality of Working Life Series
LA English
DT Article; Book Chapter
ID BEHAVIOR; STRESS; WORK
C1 [Macik-Frey, Marilyn] Nicholls State Univ, Thibodaux, LA 70310 USA.
[Quick, James Campbell] Univ Texas Arlington, Arlington, TX 76019 USA.
[Quick, James Campbell; Cooper, Cary L.] Univ Lancaster, Sch Management, Lancaster LA1 4YW, England.
[Mack, David A.] Univ Texas Arlington, Goolsby Leadership Acad, Coll Business, Arlington, TX 76019 USA.
[Keller, Nathan] USA, Mental Hlth Cavalry Div 1, Washington, DC USA.
RP Macik-Frey, M (reprint author), Nicholls State Univ, Thibodaux, LA 70310 USA.
NR 40
TC 1
Z9 1
U1 0
U2 0
PU INFORMATION AGE PUBLISHING-IAP
PI CHARLOTTE
PA PO BOX 79049, CHARLOTTE, NC 28271-7047 USA
BN 978-1-60752-058-0
J9 STRESS QUAL WORK LIF
PY 2009
BP 95
EP 121
PG 27
WC Psychology, Applied; Management
SC Psychology; Business & Economics
GA BKM47
UT WOS:000268494300006
ER
PT J
AU Helfstein, S
Meese, MJ
Rassler, D
Sawyer, R
Schnack, T
Sheiffer, M
Silverstone, S
Taylor, S
AF Helfstein, Scott
Meese, Michael J.
Rassler, Don
Sawyer, Reid
Schnack, Troy
Sheiffer, Mathew
Silverstone, Scott
Taylor, Scott
TI White Paper Prepared for The Secretary of Defense Task Force on DoD
Nuclear Weapons Management: Tradeoffs and Paradoxes: Terrorism,
Deterrence and Nuclear Weapons
SO STUDIES IN CONFLICT & TERRORISM
LA English
DT Review
ID SUICIDE TERRORISM; RESOURCES; SANCTIONS; ATTACKS
AB This article was written at the request of the Secretary of Defense Task Force on DoD Nuclear Weapons Management. While this analysis suggests that certain types of terrorists can be deterred from certain types of attacks, it is less optimistic about the use of nuclear weapons in a terrorist deterrent strategy. A broad approach to deterrence may be effective against certain types of terrorist groups and attacks, making it crucially important to disaggregate the terrorist threat when setting policy. The article goes on to address two types of terrorist groups with a oglobal reacho that pose a serious threat to the United States: non-state actors driven by doctrines permitting catastrophic attacks and state-sponsored groups capable of carrying out catastrophic attacks. The analysis reveals a number of previously unappreciated tradeoffs and paradoxes associated with the deterrence of terrorists.
C1 [Helfstein, Scott; Meese, Michael J.; Rassler, Don; Sawyer, Reid; Schnack, Troy; Sheiffer, Mathew; Silverstone, Scott; Taylor, Scott] US Mil Acad, Dept Social Sci, Combating Terrorism Ctr, West Point, NY 10996 USA.
RP Helfstein, S (reprint author), US Mil Acad, Dept Social Sci, Combating Terrorism Ctr, Lincoln Hall, West Point, NY 10996 USA.
EM scott.helfstein@usma.edu
NR 104
TC 1
Z9 1
U1 0
U2 8
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
SN 1057-610X
J9 STUD CONFL TERROR
JI Stud. Confl. Terror.
PY 2009
VL 32
IS 9
BP 776
EP 801
AR PII 914014634
DI 10.1080/10576100903124049
PG 26
WC International Relations; Political Science
SC International Relations; Government & Law
GA 485DE
UT WOS:000269100200002
ER
PT J
AU Vittori, J
Bremer, K
Vittori, P
AF Vittori, Jodi
Bremer, Kristin
Vittori, Pasquale
TI Islam in Tanzania and Kenya: Ally or Threat in the War on Terror?
SO STUDIES IN CONFLICT & TERRORISM
LA English
DT Article
AB This article explores the historical emergence of Islam in East Africa, details the political background of Tanzania and Kenya, the role of Islam in each country, and U.S. foreign policy in the region. The recent U.S. strategy of intelligence-sharing with Kenya, training and military support to both Kenya and Tanzania, and air strikes in Somalia are assessed. In addition to the current military emphasis, the United States should incorporate more osofto options, such as the promotion of democratic governance in these nascent democracies through political assistance in constitutional, judicial, and law-enforcement reform, as well as encouraging greater inclusion of Muslims in the political system.
C1 [Vittori, Jodi] USAF, Washington, DC 20330 USA.
[Bremer, Kristin] Kutztown State Univ, Dept Polit Sci, Kutztown, PA USA.
[Vittori, Pasquale] USA, Washington, DC 20310 USA.
RP Vittori, J (reprint author), USAF, Washington, DC 20330 USA.
EM jodimat@hotmail.com
NR 35
TC 1
Z9 1
U1 0
U2 2
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
SN 1057-610X
J9 STUD CONFL TERROR
JI Stud. Confl. Terror.
PY 2009
VL 32
IS 12
BP 1075
EP 1099
AR PII 917321509
DI 10.1080/10576100903319805
PG 25
WC International Relations; Political Science
SC International Relations; Government & Law
GA 528XP
UT WOS:000272480600004
ER
PT J
AU Todd, CS
Abed, AMS
Scott, PT
Safi, N
Earhart, KC
Strathdee, SA
AF Todd, Catherine S.
Abed, Abdullah M. S.
Scott, Paul T.
Safi, Naqibullah
Earhart, Kenneth C.
Strathdee, Steffanie A.
TI A Cross-Sectional Assessment of Utilization of Addiction Treatment among
Injection Drug Users in Kabul, Afghanistan
SO SUBSTANCE USE & MISUSE
LA English
DT Article
DE Afghanistan; detoxification; injecting drug user; addiction treatment;
needle exchange program
ID METHADONE-MAINTENANCE; COST-EFFECTIVENESS; HARM REDUCTION; HIV;
PREVENTION; PREVALENCE; PROGRAMS; COHORT; CHINA; RISK
AB The purpose of this study was to describe prior use of detoxification and addiction-treatment programs among injection drug users (IDUs) in Kabul, Afghanistan. From 2005-2006, IDUs (n = 464) recruited into this cross-sectional study completed an interviewer-administered questionnaire and whole blood rapid testing with fingerstick samples for HIV, syphilis, and hepatitis C antibody and B surface antigen testing. Participants were predominantly male (99.8%), Afghan (98.9%), and had little formal education. Correlates of detoxification and addiction treatment were identified with logistic regression. The majority (94.0%, n = 435) felt great/urgent need for treatment, of whom 56.3% (n = 245) reported inability to access treatment. Prior detoxification was associated with new needle use with each injection (AOR = 1.91, 95% CI: 1.12-3.26) and prior incarceration (AOR = 1.81, 95% CI: 1.04-3.13). The study's limitations are noted. Rapid scale-up and subsidy of needle and syringe programs and opioid agonist treatment is urgently needed in Kabul.
C1 [Todd, Catherine S.; Strathdee, Steffanie A.] Univ Calif San Diego, Dept Family & Prevent Med, San Diego, CA 92103 USA.
[Abed, Abdullah M. S.; Safi, Naqibullah] Minist Publ Hlth, Natl HIV AIDS Control Program, Kabul, Afghanistan.
[Scott, Paul T.] US Mil HIV Res Program, Div Retrovirol, Walter Reed Army Inst Res, Rockville, MD USA.
[Earhart, Kenneth C.] USN, Med Res Unit 3, Virol Res Program, Cairo, Egypt.
[Todd, Catherine S.] Univ Calif San Diego, Div Int Hlth & Cross Cultural Med, San Diego, CA 92103 USA.
[Strathdee, Steffanie A.] Univ Calif San Diego, Sch Med, Dept Family & Prevent Med, Harold Simon Chair, La Jolla, CA 92093 USA.
[Strathdee, Steffanie A.] Univ Calif San Diego, Sch Med, Dept Family & Prevent Med, Div Int Hlth & Cross Cultural Med, La Jolla, CA 92093 USA.
RP Todd, CS (reprint author), 9500 Gilman Dr,Mailstop 0622, La Jolla, CA 92093 USA.
EM cstodd@ucsd.edu
RI Strathdee, Steffanie/B-9042-2009
FU FIC NIH HHS [K01TW007408]
NR 34
TC 4
Z9 4
U1 0
U2 3
PU INFORMA HEALTHCARE
PI LONDON
PA TELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLAND
SN 1082-6084
J9 SUBST USE MISUSE
JI Subst. Use Misuse
PY 2009
VL 44
IS 3
BP 416
EP 430
AR PII 905008207
DI 10.1080/10826080802347669
PG 15
WC Substance Abuse; Psychiatry; Psychology
SC Substance Abuse; Psychiatry; Psychology
GA 406JW
UT WOS:000263291800008
PM 18979391
ER
PT J
AU Rotmann, P
Tohn, D
Wharton, J
AF Rotmann, Philipp
Tohn, David
Wharton, Jaron
TI Learning Under Fire: Progress and Dissent in the US Military
SO SURVIVAL
LA English
DT Article
AB After initial successes, the US military suffered many painful years in Afghanistan and Iraq before undertaking the most significant retooling of any military while in active combat since the German Army in 1917. The change to a counter-insurgency posture was catalysed by a combination of junior leadership responding to the tactical problems that confronted them and senior institutional dissidents driving deep, controversial changes in doctrine and culture to meet the new requirements. Both components were necessary, but neither was sufficient on its own. They were the product of an institutional culture that strove to be self-learning, with varying levels of success. Specific recommendations recognise, preserve and advance this dynamic in anticipation of future requirements for rapid change in response to the next conflict.
C1 [Rotmann, Philipp] Harvard Univ, John F Kennedy Sch Govt, Cambridge, MA 02138 USA.
[Tohn, David; Wharton, Jaron] USA, Washington, DC USA.
RP Rotmann, P (reprint author), Harvard Univ, John F Kennedy Sch Govt, Cambridge, MA 02138 USA.
NR 28
TC 3
Z9 3
U1 0
U2 2
PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND
SN 0039-6338
J9 SURVIVAL
JI Survival
PY 2009
VL 51
IS 4
BP 31
EP 48
AR PII 913357015
DI 10.1080/00396330903168824
PG 18
WC International Relations; Political Science
SC International Relations; Government & Law
GA 552KM
UT WOS:000274288700004
ER
PT J
AU Gentile, GP
Rid, T
Rotmann, P
Tohn, D
Wharton, J
AF Gentile, Gian P.
Rid, Thomas
Rotmann, Philipp
Tohn, David
Wharton, Jaron
TI Progress, Dissent and Counter-Insurgency: An Exchange
SO SURVIVAL
LA English
DT Editorial Material
AB In the August-September 2009 issue of Survival (vol. 51, no. 4, pp. 31-48), Philipp Rotmann, David Tohn and Jaron Wharton argued that the US military's change to a counterinsurgency posture in the on-going conflicts in Afghanistan and Iraq was catalysed by two products of an institutional culture that strove to be self-learning: the response of junior leadership to tactical problems and senior institutional dissidents driving deep, controversial changes in doctrine and culture. In this Survival Exchange two experts offer US and European perspectives on the authors' argument and recommendations to preserve and advance this dynamic in anticipation of future requirements for rapid change. A response from Rotmann, Tohn and Wharton concludes the debate.
C1 [Rotmann, Philipp] Harvard Univ, John F Kennedy Sch Govt, Cambridge, MA 02138 USA.
[Tohn, David; Wharton, Jaron] USA, Washington, DC USA.
RI Popova, Olga/A-8099-2012
NR 20
TC 2
Z9 2
U1 0
U2 1
PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND
SN 0039-6338
J9 SURVIVAL
JI Survival
PY 2009
VL 51
IS 6
BP 189
EP +
AR PII 917062983
DI 10.1080/00396330903461724
PG 16
WC International Relations; Political Science
SC International Relations; Government & Law
GA 552KO
UT WOS:000274288900012
ER
PT S
AU Thodos, WT
Mathur, NG
Lin, CF
AF Thodos, William T.
Mathur, Navin G.
Lin, Ching-Fang
BE Trommer, GF
TI Modeling, Design, Analysis, Simulation, and Evaluation (MDASE) for
Far-Target Location (FTL) Systems
SO SYMPOSIUM GYRO TECHNOLOGY 2009
SE SYMPOSIUM GYRO TECHNOLOGY
LA English
DT Proceedings Paper
CT Symposium Gyro Technology 2009
CY SEP 22-23, 2009
CL Karlsruhe, GERMANY
SP Univ Karlsruhe, Inst Syst Optimizat, German Inst Navigat
AB This paper describes aspects of Modeling, Design, Analysis, Simulation, and Evaluation (MDASE) in relation to gyrocompassing for Far-Target Location (FTL) systems. FTL systems provide an extensive support for many joint operations efforts, which are critical for a variety of defense users. The basic principle of gyrocompassing is to establish azimuth based on the measurement of the earth's angular velocity vector and the local gravity force vector. The US Army needs a suite of effective Modeling, Analysis, Simulation, and Evaluation tools for the design, development, implementation and validation of the gyrocompass based azimuth and attitude determination modules for the FTL systems.
C1 [Thodos, William T.] USA, Component Technol Branch, RDECOM, CERDEC,Night Vis & Elect Sensors Directorate, Ft Belvoir, VA 22060 USA.
RP Thodos, WT (reprint author), USA, Component Technol Branch, RDECOM, CERDEC,Night Vis & Elect Sensors Directorate, 10221 Burbeck Rd, Ft Belvoir, VA 22060 USA.
NR 7
TC 0
Z9 0
U1 0
U2 0
PU UNIV STUTTGART INST A FUR MECHANIK
PI 70550 STUTTGART
PA PFAFFENWALDRING 9, 70550 STUTTGART, GERMANY
SN 1439-4502
J9 SYMPOSIUM GYRO TECHN
PY 2009
PG 10
WC Automation & Control Systems; Engineering, Electrical & Electronic;
Instruments & Instrumentation
SC Automation & Control Systems; Engineering; Instruments & Instrumentation
GA BSM38
UT WOS:000284917000020
ER
PT J
AU Duddu, R
Dave, PR
Damavarapu, R
Surapaneni, R
Parrish, D
AF Duddu, Raja
Dave, Paritosh R.
Damavarapu, Reddy
Surapaneni, Rao
Parrish, Damon
TI Nucleophilic Substitution Reactions of 1-Methyl-2,4,5-trinitroimidazole
(MTNI)
SO SYNTHETIC COMMUNICATIONS
LA English
DT Article
DE Aminoimidazoles; azido compounds; nitroimidazoles; triazole
ID ENERGETIC MATERIALS; DERIVATIVES
AB Nucleophilic substitution reactions on 1-methyl-2,4,5-trinitroimidazole (MTNI) are described.
C1 [Duddu, Raja; Dave, Paritosh R.] USA, SAIC, ARDEC, Picatinny Arsenal, NJ 07806 USA.
[Parrish, Damon] USN, Res Lab, Struct Matter Lab, Washington, DC 20375 USA.
RP Duddu, R (reprint author), USA, SAIC, ARDEC, Bldg 3028, Picatinny Arsenal, NJ 07806 USA.
EM raja.duddu@us.army.mil
NR 18
TC 15
Z9 19
U1 2
U2 6
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
SN 0039-7911
J9 SYNTHETIC COMMUN
JI Synth. Commun.
PY 2009
VL 39
IS 23
BP 4282
EP 4288
AR PII 916369132
DI 10.1080/00397910902898635
PG 7
WC Chemistry, Organic
SC Chemistry
GA 525HY
UT WOS:000272207100013
ER
PT J
AU Salerno, SM
Arnett, MV
Domanski, JP
AF Salerno, Stephen M.
Arnett, Michael V.
Domanski, Jeremy P.
TI Standardized Sign-Out Reduces Intern Perception of Medical Errors on the
General Internal Medicine Ward
SO TEACHING AND LEARNING IN MEDICINE
LA English
DT Article
ID PATIENT-CARE; COMMUNICATION; SUGGESTIONS; SAFETY; SYSTEM; IMPACT
AB Background: Prior research on reducing variation in housestaff handoff procedures have depended on proprietary checkout software. Use of low-technology standardization techniques has not been widely studied. Purpose: We wished to determine if standardizing the process of intern sign-out using low-technology sign-out tools could reduce perception of errors and missing handoff data. Methods: We conducted a pre-post prospective study of a cohort of 34 interns on a general internal medicine ward. Night interns coming off duty and day interns reassuming care were surveyed on their perception of erroneous sign-out data, mistakes made by the night intern overnight, and occurrences unanticipated by sign-out. Trainee satisfaction with the sign-out process was assessed with a 5-point Likert survey. Results: There were 399 intern surveys performed 8 weeks before and 6 weeks after the introduction of a standardized sign-out form. The response rate was 95% for the night interns and 70% for the interns reassuming care in the morning. After the standardized form was introduced, night interns were significantly (p .003) less likely to detect missing sign-out data including missing important diseases, contingency plans, or medications. Standardized sign-out did not significantly alter the frequency of dropped tasks or missed lab and X-ray data as perceived by the night intern. However, the day teams thought there were significantly less perceived errors on the part of the night intern (p = .001) after introduction of the standardized sign-out sheet. There was no difference in mean Likert scores of resident satisfaction with sign-out before and after the intervention. Conclusion: Standardized written sign-out sheets significantly improve the completeness and effectiveness of handoffs between night and day interns. Further research is needed to determine if these process improvements are related to better patient outcomes.
C1 [Salerno, Stephen M.; Arnett, Michael V.; Domanski, Jeremy P.] Tripler Army Med Ctr, Dept Med, Honolulu, HI 96859 USA.
RP Salerno, SM (reprint author), Tripler Army Med Ctr, Dept Med, Honolulu, HI 96859 USA.
EM stephen.salerno@us.army.mil
NR 16
TC 28
Z9 28
U1 0
U2 4
PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND
SN 1040-1334
J9 TEACH LEARN MED
JI Teach. Learn. Med.
PY 2009
VL 21
IS 2
BP 121
EP 126
AR PII 909979899
DI 10.1080/10401330902791354
PG 6
WC Education, Scientific Disciplines; Health Care Sciences & Services
SC Education & Educational Research; Health Care Sciences & Services
GA 425OG
UT WOS:000264646400008
PM 19330690
ER
PT J
AU Goodwin, GF
Burke, CS
Wildman, JL
Salas, E
AF Goodwin, Gerald F.
Burke, C. Shawn
Wildman, Jessica L.
Salas, Eduardo
BE Salas, E
Goodwin, GF
Burke, CS
TI Team Effectiveness in Complex Organizations: An Overview
SO TEAM EFFECTIVENESS IN COMPLEX ORGANIZATIONS: CROSS-DISCIPLINARY
PERSPECTIVES AND APPROACHES
SE SIOP Organizational Frontiers Series
LA English
DT Article; Book Chapter
ID WORK TEAMS; TRAINING WORK; MODEL; EXTENSION; BEHAVIOR; TIME
C1 [Goodwin, Gerald F.] USA, Res Inst Behav & Social Sci, Washington, DC USA.
[Salas, Eduardo] Univ Cent Florida, Inst Simulat & Training, Human Syst Integrat Res Dept, Orlando, FL 32816 USA.
[Wildman, Jessica L.] Univ Cent Florida, Ind & Org Psychol Program, Orlando, FL 32816 USA.
[Wildman, Jessica L.] USA, Res Lab, Washington, DC USA.
[Salas, Eduardo] Amer Psychol Assoc, New York, NY USA.
RP Goodwin, GF (reprint author), USA, Res Inst Behav & Social Sci, Washington, DC USA.
NR 47
TC 5
Z9 6
U1 0
U2 3
PU PSYCHOLOGY PRESS
PI HOVE
PA 27 CHURCH ROAD, HOVE BN3 2FA, E SUSSEX, ENGLAND
BN 978-0-8058-5881-5
J9 SIOP ORGAN FRONT SER
PY 2009
BP 3
EP 16
PG 14
WC Psychology, Applied; Management
SC Psychology; Business & Economics
GA BUY94
UT WOS:000290753500003
ER
PT J
AU Salas, E
Goodwin, GF
Burke, CS
AF Salas, Eduardo
Goodwin, Gerald F.
Burke, C. Shawn
BE Salas, E
Goodwin, GF
Burke, CS
TI Team Effectiveness in Complex Organizations Cross-Disciplinary
Perspectives and Approaches Preface
SO TEAM EFFECTIVENESS IN COMPLEX ORGANIZATIONS: CROSS-DISCIPLINARY
PERSPECTIVES AND APPROACHES
SE SIOP Organizational Frontiers Series
LA English
DT Editorial Material; Book Chapter
C1 [Salas, Eduardo] Univ Cent Florida, Inst Simulat & Training, Human Syst Integrat Res Dept, Orlando, FL 32816 USA.
[Goodwin, Gerald F.] USA, Res Inst, Washington, DC USA.
[Goodwin, Gerald F.] USA, Res Inst Behav & Social Sci, Washington, DC USA.
[Salas, Eduardo] Amer Psychol Assoc, New York, NY USA.
RP Salas, E (reprint author), Univ Cent Florida, Inst Simulat & Training, Human Syst Integrat Res Dept, Orlando, FL 32816 USA.
NR 0
TC 0
Z9 0
U1 0
U2 2
PU PSYCHOLOGY PRESS
PI HOVE
PA 27 CHURCH ROAD, HOVE BN3 2FA, E SUSSEX, ENGLAND
BN 978-0-8058-5881-5
J9 SIOP ORGAN FRONT SER
PY 2009
BP XV
EP XVI
PG 2
WC Psychology, Applied; Management
SC Psychology; Business & Economics
GA BUY94
UT WOS:000290753500002
ER
PT J
AU Salas, E
Rosen, MA
Burke, CS
Goodwin, GF
AF Salas, Eduardo
Rosen, Michael A.
Burke, C. Shawn
Goodwin, Gerald F.
BE Salas, E
Goodwin, GF
Burke, CS
TI The Wisdom of Collectives in Organizations: An Update of the Teamwork
Competencies
SO TEAM EFFECTIVENESS IN COMPLEX ORGANIZATIONS: CROSS-DISCIPLINARY
PERSPECTIVES AND APPROACHES
SE SIOP Organizational Frontiers Series
LA English
DT Article; Book Chapter
ID SHARED MENTAL MODELS; RELATIONSHIP CONFLICT; SITUATION AWARENESS; WORK
TEAMS; TRANSACTIVE MEMORY; COGNITIVE-ABILITY; GROUP-PERFORMANCE;
MANAGEMENT TEAMS; DECISION-MAKING; TASK
C1 [Salas, Eduardo] Univ Cent Florida, Human Syst Integrat Res Dept, Inst Simulat & Training, Orlando, FL 32816 USA.
[Salas, Eduardo] UCF, Appl Expt & Human Factors Ph D Program, Orlando, FL USA.
[Salas, Eduardo] NAWC TSD, Training Technol Dev Branch, Orlando, FL USA.
[Salas, Eduardo] Amer Psychol Assoc, Washington, DC USA.
[Salas, Eduardo] Human Factors & Ergon Soc, Santa Monica, CA USA.
[Rosen, Michael A.] Univ Cent Florida, Appl Expt & Human Factors Psychol Program, Orlando, FL 32816 USA.
[Goodwin, Gerald F.] USA, Res Inst Behav & Social Sci, Washington, DC USA.
[Goodwin, Gerald F.] Dept Def, Washington, DC USA.
[Goodwin, Gerald F.] Amer Inst Res, Washington, DC USA.
RP Salas, E (reprint author), Univ Cent Florida, Human Syst Integrat Res Dept, Inst Simulat & Training, Orlando, FL 32816 USA.
NR 157
TC 42
Z9 44
U1 1
U2 4
PU PSYCHOLOGY PRESS
PI HOVE
PA 27 CHURCH ROAD, HOVE BN3 2FA, E SUSSEX, ENGLAND
BN 978-0-8058-5881-5
J9 SIOP ORGAN FRONT SER
PY 2009
BP 39
EP 79
PG 41
WC Psychology, Applied; Management
SC Psychology; Business & Economics
GA BUY94
UT WOS:000290753500005
ER
PT J
AU DeChurch, LA
Mathieu, JE
AF DeChurch, Leslie A.
Mathieu, John E.
BE Salas, E
Goodwin, GF
Burke, CS
TI Thinking in Terms of Multiteam Systems
SO TEAM EFFECTIVENESS IN COMPLEX ORGANIZATIONS: CROSS-DISCIPLINARY
PERSPECTIVES AND APPROACHES
SE SIOP Organizational Frontiers Series
LA English
DT Article; Book Chapter
ID TEAM EFFECTIVENESS; WORK TEAMS; EMPOWERMENT; TASK; INTERDEPENDENCE;
PERFORMANCE; ANTECEDENTS; MODEL; DIMENSIONS; MANAGEMENT
C1 [DeChurch, Leslie A.] Univ Cent Florida, DELTA Res Lab, Orlando, FL 32816 USA.
[DeChurch, Leslie A.] USA, Res Inst Behav & Social Sci, Washington, DC USA.
[Mathieu, John E.] Univ Connecticut, Storrs, CT 06269 USA.
[Mathieu, John E.] Amer Psychol Assoc, New York, NY USA.
RP DeChurch, LA (reprint author), Univ Cent Florida, DELTA Res Lab, Orlando, FL 32816 USA.
NR 50
TC 12
Z9 12
U1 2
U2 7
PU PSYCHOLOGY PRESS
PI HOVE
PA 27 CHURCH ROAD, HOVE BN3 2FA, E SUSSEX, ENGLAND
BN 978-0-8058-5881-5
J9 SIOP ORGAN FRONT SER
PY 2009
BP 267
EP 292
PG 26
WC Psychology, Applied; Management
SC Psychology; Business & Economics
GA BUY94
UT WOS:000290753500012
ER
PT J
AU Essens, PJMD
Vogelaar, ALW
Mylle, JJC
Blendell, C
Paris, C
Halpin, SM
Baranski, JV
AF Essens, Peter J. M. D.
Vogelaar, Ad L. W.
Mylle, Jacques J. C.
Blendell, Carol
Paris, Carol
Halpin, Stanley M.
Baranski, Joseph V.
BE Salas, E
Goodwin, GF
Burke, CS
TI Team Effectiveness in Complex Settings: A Framework
SO TEAM EFFECTIVENESS IN COMPLEX ORGANIZATIONS: CROSS-DISCIPLINARY
PERSPECTIVES AND APPROACHES
SE SIOP Organizational Frontiers Series
LA English
DT Article; Book Chapter
ID PERSON-ENVIRONMENT FIT; LEADERSHIP; PERFORMANCE; ORGANIZATIONS
C1 [Mylle, Jacques J. C.] Royal Mil Acad, Dept Psychol, Brussels, Belgium.
[Halpin, Stanley M.] Kansas State Univ, Grad Sch, Manhattan, KS 66506 USA.
[Halpin, Stanley M.] USA, Res Inst, Res Grp, Ft Leavenworth, KS USA.
[Baranski, Joseph V.] Def Res & Dev Canada, Collaborat Performance & Learning Sect, Toronto, ON, Canada.
NR 58
TC 9
Z9 10
U1 0
U2 0
PU PSYCHOLOGY PRESS
PI HOVE
PA 27 CHURCH ROAD, HOVE BN3 2FA, E SUSSEX, ENGLAND
BN 978-0-8058-5881-5
J9 SIOP ORGAN FRONT SER
PY 2009
BP 293
EP 320
PG 28
WC Psychology, Applied; Management
SC Psychology; Business & Economics
GA BUY94
UT WOS:000290753500013
ER
PT J
AU Salas, E
Wildman, JL
AF Salas, Eduardo
Wildman, Jessica L.
BE Salas, E
Goodwin, GF
Burke, CS
TI Ten Critical Research Questions: The Need for New and Deeper
Explorations
SO TEAM EFFECTIVENESS IN COMPLEX ORGANIZATIONS: CROSS-DISCIPLINARY
PERSPECTIVES AND APPROACHES
SE SIOP Organizational Frontiers Series
LA English
DT Article; Book Chapter
ID TEAM MENTAL MODELS; TRANSACTIVE MEMORY; WORK GROUPS;
SOFTWARE-DEVELOPMENT; SITUATION AWARENESS; MULTITEAM SYSTEMS;
COGNITIVE-ABILITY; MANAGEMENT TEAMS; PERFORMANCE; KNOWLEDGE
C1 [Salas, Eduardo] Univ Cent Florida, Human Syst Integrat Res Dept, Inst Simulat & Training, Orlando, FL 32816 USA.
[Salas, Eduardo] UCF, Appl Expt & Human Factors Ph D Program, Orlando, FL USA.
[Salas, Eduardo] Amer Psychol Assoc, New York, NY USA.
[Wildman, Jessica L.] Univ Cent Florida, Ind & Org Psychol Program, Orlando, FL 32816 USA.
[Wildman, Jessica L.] USA, Res Lab, Washington, DC USA.
RP Salas, E (reprint author), Univ Cent Florida, Human Syst Integrat Res Dept, Inst Simulat & Training, Orlando, FL 32816 USA.
NR 114
TC 4
Z9 5
U1 1
U2 3
PU PSYCHOLOGY PRESS
PI HOVE
PA 27 CHURCH ROAD, HOVE BN3 2FA, E SUSSEX, ENGLAND
BN 978-0-8058-5881-5
J9 SIOP ORGAN FRONT SER
PY 2009
BP 525
EP 546
PG 22
WC Psychology, Applied; Management
SC Psychology; Business & Economics
GA BUY94
UT WOS:000290753500022
ER
PT S
AU Dwight, LW
Jensen, JO
AF Woolard, Dwight L.
Jensen, James O.
BE Linden, KJ
Sadwick, LP
OSullivan, CMM
TI Advanced nanoelectronic architectures for THz-based biological agent
detection
SO TERAHERTZ TECHNOLOGY AND APPLICATIONS II
SE Proceedings of SPIE
LA English
DT Proceedings Paper
CT Conference on Terahertz Technology and Applications II
CY JAN 28-29, 2009
CL San Jose, CA
SP SPIE
DE nanoscale; electronic architectures; terahertz signatures; biological
agents; detection
AB The U.S. Army Research Office (ARO) and the U.S. Army Edgewood Chemical Biological Center (ECBC) jointly lead and support novel research programs that are advancing the state-of-the-art in nanoelectronic engineering in application areas that have relevance to national defense and security. One fundamental research area that is presently being emphasized by ARO and ECBC is the exploratory investigation of new bio-molecular architectural concepts that can be used to achieve rapid, reagent-less detection and discrimination of biological warfare (BW) agents, through the control of multi-photon and multi-wavelength processes at the nanoscale. This paper will overview an ARO/ECBC led multidisciplinary research program presently under the support of the U.S. Defense Threat Reduction Agency (DTRA) that seeks to develop new devices and nanoelectronic architectures that are effective for extracting THz signatures from target bio-molecules. Here, emphasis will be placed on the new nanosensor concepts and THz/Optical measurement methodologies for spectral-based sequencing/identification of genetic molecules.
C1 [Woolard, Dwight L.] USA, Res Off, Durham, NC 27709 USA.
RP Dwight, LW (reprint author), USA, Res Off, Durham, NC 27709 USA.
EM dwight.woolard@us.army.mil
NR 13
TC 0
Z9 0
U1 1
U2 2
PU SPIE-INT SOC OPTICAL ENGINEERING
PI BELLINGHAM
PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
SN 0277-786X
BN 978-0-8194-7461-2
J9 PROC SPIE
PY 2009
VL 7215
AR 72150K
DI 10.1117/12.809127
PG 15
WC Engineering, Electrical & Electronic; Nanoscience & Nanotechnology;
Instruments & Instrumentation; Optics; Spectroscopy
SC Engineering; Science & Technology - Other Topics; Instruments &
Instrumentation; Optics; Spectroscopy
GA BST70
UT WOS:000285751800015
ER
PT B
AU Gooch, W
Showalter, D
Burkins, M
Montgomery, J
Squillacioti, R
Nichols, A
Martin, L
Bailey, R
Swiatek, G
AF Gooch, William
Showalter, Dwight
Burkins, Matthew
Montgomery, Jonathan
Squillacioti, Richard
Nichols, Andrew
Martin, Larry
Bailey, Ronald
Swiatek, Glenn
GP TMS
TI DEVELOPMENT AND BALLISTIC TESTING OF A NEW CLASS OF AUTO-TEMPERED HIGH
HARD STEELS UNDER MILITARY SPECIFICATION MIL-DTL-46100E
SO TMS 2009 138TH ANNUAL MEETING & EXHIBITION - SUPPLEMENTAL PROCEEDINGS,
VOL 3: GENERAL PAPER SELECTIONS
LA English
DT Proceedings Paper
CT 138th TMS Annual Meeting and Exhibition
CY FEB 15-19, 2009
CL San Francisco, CA
DE High Hard Steel; MIL-DTL46100E; Auto-tempered; Ballistic Testing; Armor
AB The US Army Research Laboratory (ARL) was directed to investigate various ways to expand current steel armor plate production as the large military demand for armor plate exceeded the current production capacity at US steel facilities for quench and tempered high hard armor (HHA) steel plate. The solution was to expand the availability of HHA steels under the current HHA military specification (MIL-DTL-46100) to include a new class of air-quenched, auto-tempered steels that do not use existing water quench and temper facilities. Allegheny Technologies Incorporated (ATI) developed an auto-tempered steel alloy ATI 500-MIL (TM) that has physical and mechanical properties that meet the current HHA specification. ARL procured sufficient amounts of ATI 500-MIL (TM) plate to allow acceptance testing and subsequent certification of ATI 500-MIL (TM) plate as complying with the First Article requirements of the newly revised MIL-DTL-46100E specification. This paper documents the development of ATI 500-MIL (TM) plate and subsequent ballistic testing and inclusion into the specification as Class 2 auto-tempered HHA steel.
C1 [Gooch, William; Showalter, Dwight; Burkins, Matthew; Montgomery, Jonathan; Squillacioti, Richard] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Gooch, W (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
NR 5
TC 2
Z9 2
U1 1
U2 3
PU MINERALS, METALS & MATERIALS SOC
PI WARRENDALE
PA 184 THORN HILL RD, WARRENDALE, PA 15086-7514 USA
BN 978-0-87339-740-7
PY 2009
BP 321
EP 328
PG 8
WC Materials Science, Multidisciplinary; Metallurgy & Metallurgical
Engineering; Mineralogy
SC Materials Science; Metallurgy & Metallurgical Engineering; Mineralogy
GA BJC17
UT WOS:000264675200041
ER
PT J
AU Woo, S
Pham, D
Muhin, I
Du, N
Wintz, H
Guan, X
PerKins, E
Vulpe, C
AF Woo, Seonock
Pham, Don
Muhin, Irma
Du, Nick
Wintz, Henri
Guan, Xin
PerKins, Edward
Vulpe, Chris
TI Screening of Differentially Expressed Genes of Fathead Minnow Exposed to
Hexahydro-1,3,5-Trinitro-1,3,5-Triazine Using Microarray
SO TOXICOLOGIC PATHOLOGY
LA English
DT Meeting Abstract
C1 [Woo, Seonock; Pham, Don; Muhin, Irma; Du, Nick; Wintz, Henri; Vulpe, Chris] UC Berkeley, Berkeley, CA USA.
[Guan, Xin; PerKins, Edward] USA, Corps Engineer Res & Dev Ctr, Vicksburg, MS USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 0192-6233
J9 TOXICOL PATHOL
JI Toxicol. Pathol.
PD JAN
PY 2009
VL 37
IS 1
MA P69
BP 144
EP 144
PG 1
WC Pathology; Toxicology
SC Pathology; Toxicology
GA 463XE
UT WOS:000267466500082
ER
PT J
AU Brimfield, AA
Mancebo, AM
Mason, RP
Jiang, JJ
Siraki, AG
Novak, MJ
AF Brimfield, A. A.
Mancebo, A. M.
Mason, R. P.
Jiang, J. J.
Siraki, A. G.
Novak, M. J.
TI Free radical production from the interaction of 2-chloroethyl vesicants
(mustard gas) with pyridine nucleotide-driven flavoprotein electron
transport systems
SO TOXICOLOGY AND APPLIED PHARMACOLOGY
LA English
DT Article
DE Chemical warfare; Flavoenzyme; Chloroethyl mustards; Onium ion;
Enzymatic reduction; Electron transport; Free radical; EPR
ID NITRIC-OXIDE SYNTHASE; SULFUR MUSTARD; THIOREDOXIN REDUCTASE; SULFONIUM
SALTS; IN-VITRO; MECHANISM; TOXICITY; DRUG; IDENTIFICATION; PROCARBAZINE
AB The biochemical sequelae to chloroethyl mustard exposure correspond very well to toxic processes initiated by free radicals. Additionally, mustard solutions contain spontaneously formed cyclic onium ions which produce carbon free radicals when reduced electrochemically. Therefore, we hypothesized that the onium ions of sulfur or nitrogen mustards might produce carbon free radicals upon being reduced enzymatically, and that these radicals might constitute a metabolic activation. We set out to document radical production using an in vitro metabolic system and electron paramagnetic resonance (EPR). Our system consisted of NADPH, one of several pyridine nucleotide-driven flavoprotein reductases, cytochrome c as a terminal electron acceptor, various sulfur or nitrogen mustards and the spin trap alpha-[4-pyridyl-1-oxide]-N-tertbutylnitrone in buffer. Reactions were started by adding the reductase to the other materials, vortexing and immediately transferring the mixture to a 10 mm EPR flat cell. Repeated scans on a Bruker ESP 300E EPR spectrometer produced a triplet of doublets with hyperfine splitting constants of a(N) = 15.483 G and a(H)=2.512 G. The outcome supported our hypothesis that carbon-centered free radicals are produced when mustard-related onium ions are enzymatically reduced. The EPR results varied little with the chloroethyl compound used or with porcine or human cytochrome P450 reductase, the reductase domain of rat brain neuronal nitric oxide synthase or rat liver thioredoxin reductase. Our results offer new insight into the basis for mustard-induced vesication and the outcome of exposure to different mustards. The free radical model provides an explanation for similarities in the lesions arising from mustard exposure and energy-based lesions such as those from heat, ultraviolet and nuclear radiation as well as damage across tissue types such as skin, eyes or airway epithelium. Published by Elsevier Inc.
C1 [Brimfield, A. A.; Mancebo, A. M.] USA, Med Res Inst Chem Def, Aberdeen Proving Ground, MD 21010 USA.
[Mason, R. P.; Jiang, J. J.; Siraki, A. G.] NIEHS, Lab Pharmacol & Chem, Res Triangle Pk, NC 27709 USA.
[Novak, M. J.] Florida Inst Technol, Dept Chem, Melbourne, FL 32901 USA.
RP Brimfield, AA (reprint author), USA, Med Res Inst Chem Def, Aberdeen Proving Ground, MD 21010 USA.
EM alan.a.brimfield@us.army.mil
FU Defense Threat Reduction Agency; Joint Science and Technology Office;
U.S. Army Medical Research and Materiel Command; Intramural Research
Program of the NIH; [17-00-2-008]
FX This work was supported by the Defense Threat Reduction Agency - Joint
Science and Technology Office, Medical S and T Division and, in part, by
award number DAMD 17-00-2-008 from the U.S. Army Medical Research and
Materiel Command. This research was also Supported in part by the
Intramural Research Program of the NIH, National Institute of
Environmental Health Sciences. Thanks are due to Dr. Carmen Arroyo and
Mr. Brendon Gallagher of USAMRICD for helping to get this work started.
We are grateful to Professor Bettie Sue Masters of the Department of
Biochemistry, University of Texas Health Sciences Center, San Antonio,
for the kind gift of recombinant rat brain nNOS reductase domain and
recombinant porcine liver NADPHcytochrome P450 redUctase and to Dr.
Thomas M. Shea of that laboratory for generous advice. And finally, we
would like to express our thanks to Dr. MarkA. Zottola and Dr. Sunil D.
Soni of USAMRICD for discussions that were inevitably helpful and
enlightening.
NR 43
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Z9 17
U1 0
U2 5
PU ACADEMIC PRESS INC ELSEVIER SCIENCE
PI SAN DIEGO
PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA
SN 0041-008X
EI 1096-0333
J9 TOXICOL APPL PHARM
JI Toxicol. Appl. Pharmacol.
PD JAN 1
PY 2009
VL 234
IS 1
BP 128
EP 134
DI 10.1016/j.taap.2008.10.002
PG 7
WC Pharmacology & Pharmacy; Toxicology
SC Pharmacology & Pharmacy; Toxicology
GA 397SL
UT WOS:000262682300014
PM 18977373
ER
PT J
AU Quinn, MJ
McFarland, CA
Johnson, MS
AF Quinn, Michael J., Jr.
McFarland, Craig A.
Johnson, Mark S.
TI Unsuitability of the Northern Bobwhite as a Model Species for the
Assessment of Reproductive Behavior in Toxicological Studies
SO TOXICOLOGY MECHANISMS AND METHODS
LA English
DT Article
DE Avian; reproduction; behavior; toxicology; quail
ID JAPANESE-QUAIL; DISRUPTING CHEMICALS; ENDOCRINE; EXPOSURE; TOXICITY
AB The northern bobwhite (Colinus virginianus) is used in numerous wildlife toxicity studies, however no published reports could be located that mention the measurement of reproductive behavior in this species. Changes in reproductive behavior can be potentially more sensitive to environmental contaminant exposures and less resilient than more traditional physiological responses. Male bobwhite copulatory behaviors were measured similarly to those that are well established for use in Japanese quail (Coturnix japonica). Time to initiate mating, time to achieve a successful copulation, the number of mating attempts, and the number of successful copulations were recorded daily for four consecutive days over a period of 3 min for each male/female pair of birds per day. When females were introduced to male cages, males were more occupied with shows of aggression towards neighboring males than attempts to mate with the female sharing their space. Only one male successfully mated with a female over the entire 4 days of the test. Future attempts at assessing reproductive behavior in this species may be more successful if birds are separated from the rest of the group when paired. The Japanese quail seems to be a more appropriate species for overall reproductive tests due to: willingness of males to copulate in the presence of other males, consistent egg laying ability, and the short time required for embryonic development and reproductive maturity.
C1 [Quinn, Michael J., Jr.; McFarland, Craig A.; Johnson, Mark S.] USA, Ctr Hlth Promot & Prevent Med, Hlth Effects Res Program, Directorate Toxicol, Aberdeen Proving Ground, MD 21222 USA.
RP Quinn, MJ (reprint author), USA, Ctr Hlth Promot & Prevent Med, Hlth Effects Res Program, Directorate Toxicol, Edgewood Area,Bldg E-2100, Aberdeen Proving Ground, MD 21222 USA.
EM micheal.james.quinn@us.army.mil
NR 11
TC 0
Z9 0
U1 0
U2 3
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
SN 1537-6516
EI 1537-6524
J9 TOXICOL MECH METHOD
JI Toxicol. Mech. Methods
PY 2009
VL 19
IS 1
BP 40
EP 43
DI 10.1080/15376510802226482
PG 4
WC Toxicology
SC Toxicology
GA 378CX
UT WOS:000261299800005
PM 19778231
ER
PT J
AU Guarisco, JA
O'Donnell, JC
Skovira, JW
McDonough, JH
Shih, TM
AF Guarisco, John A.
O'Donnell, John C.
Skovira, Jacob W.
McDonough, John H.
Shih, Tsung-Ming
TI In vivo oxime administration does not influence Ellman
acetylcholinesterase assay results
SO TOXICOLOGY MECHANISMS AND METHODS
LA English
DT Article
DE Acetylcholinesterase; acetylthiocholine; Ellman assay; in vivo; oxime
ID ORGANOPHOSPHORUS NERVE AGENTS; CARBOXYLESTERASE INHIBITION;
CHOLINESTERASE ACTIVITY; PRALIDOXIME CHLORIDE; SOMAN TOXICITY;
HYDROLYSIS; PLASMA; 2-PAM; INTOXICATION; REACTIVATOR
AB Organophosphorus compounds (OPs) are potent inhibitors of acetylcholinesterase (AChE). Treatment for OP poisoning is by administration of atropine sulfate, an oxime, and diazepam. Oximes such as 2-PAM are used to reactivate OP-inhibited AChE so as to restore normal enzymatic function and serve as a true antidote. There are reports of non-enzymatic hydrolysis by oximes of acetylthiocholine in in vitro preparations in the widely used Ellman assay for AChE activity, which may confound the interpretation of AChE activity by producing elevated results. The purpose of this experiment was to determine if there is appreciable interference by therapeutic levels of oximes on the results of the Ellman assay in assessing AChE reactivation by oxime compounds in vivo. When therapeutic doses of oximes (2-PAM, HI-6, MMB-4, or MINA) were administered intramuscularly to guinea pigs and samples collected 60 min later, there was no statistical difference between oxime and saline control groups in measured AChE activity in various tissue samples, including blood. With appropriate dilution of samples prior to spectrophotometric assay, the Ellman assay is an acceptable method to measure in vivo oxime reactivation of inhibited AChE. Inclusion of an oxime control group to insure that this particular type of interference is not causing false readings in the assay is a prudent step.
C1 [Shih, Tsung-Ming] USA, Med Res Inst Chem Def, ATTN MCMR CDR P, Pharmacol Branch,Res Div, Aberdeen Proving Ground, MD 21010 USA.
RP Shih, TM (reprint author), USA, Med Res Inst Chem Def, ATTN MCMR CDR P, Pharmacol Branch,Res Div, 3100 Ricketts Point Rd, Aberdeen Proving Ground, MD 21010 USA.
EM tsungming.a.shih@us.army.mil
FU Defense Threat Reduction AgencyJoint Service and Technology Office,
Medical Science and Technology Division
FX The opinions or assertions contained herein are the private views of the
authors, and are not to be construed as reflecting the views of the
Department of the Army or the Department of Defense.
NR 42
TC 3
Z9 3
U1 0
U2 3
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
SN 1537-6524
J9 TOXICOL MECH METHOD
JI Toxicol. Mech. Methods
PY 2009
VL 19
IS 6-7
BP 379
EP 385
DI 10.1080/15376510903234773
PG 7
WC Toxicology
SC Toxicology
GA 502JW
UT WOS:000270456100001
PM 19778238
ER
PT J
AU Shih, TM
Skovira, JW
O'Donnell, JC
McDonough, JH
AF Shih, Tsung -Ming
Skovira, Jacob W.
O'Donnell, John C.
McDonough, John H.
TI Evaluation of nine oximes on in vivo reactivation of blood, brain, and
tissue cholinesterase activity inhibited by organophosphorus nerve
agents at lethal dose
SO TOXICOLOGY MECHANISMS AND METHODS
LA English
DT Article
DE Acetylcholinesterase; cholinesterase inhibitors; cholinesterase
reactivation; cyclosarin; guinea pig; HI-6; HLo7; methoxime; nerve
agents; organophosphorus compounds; oximes; pralidoxime; sarin;
trimedoxime; VR; VX
ID PINACOLYL METHYLPHOSPHONOFLUORIDATE; CRYSTAL-STRUCTURES; PYRIDINIUM
OXIMES; ACETYLCHOLINESTERASE; SOMAN; VITRO; HI-6; 2-PAM; HYDROLYSIS;
MECHANISM
AB The capability of several oximes (HI-6, HLo7, MMB-4, TMB-4, carboxime, ICD 585, ICD 692, ICD 3805, and 2-PAM) to reactivate in vivo AChE inhibited by the nerve agents sarin, cyclosarin, VX, or VR in blood, brain regions, and peripheral tissues in guinea pigs was examined and compared. Animals were injected subcutaneously with 1.0 LD(50) of sarin, cyclosarin, VR, or VX, and treated intramuscularly 5 min later with one of these compounds. Toxic signs and lethality were monitored, and tissue AChE activities were determined at 60 min after nerve agent. The animals exposed to sarin or cyclosarin, alone or with non-oxime treatment, some died within 60 min; however, when treated with an oxime, no animal died. For VR or VX, all animals survived for 60 min after exposure, with or without non-oxime or oxime therapy. These nerve agents caused differential degrees of inhibition: in whole blood sarin = cyclosarin > VR = VX; in brain regions sarin > cyclosarin > VX > VR; and in peripheral tissues sarin > VX > cyclosarin > VR. These oximes exhibited differential potency in reactivating nerve agent-inhibited AChE in various peripheral tissues, but not AChE activity in the brain regions. There was no difference in the AChE reactivating potency between the dichloride and dimethanesulfonate salts of HI-6. AChE inhibited by sarin was the most and cyclosarin the least susceptible to oxime reactivation. Overall, MMB-4 appeared to be, among all oximes tested, the most effective in vivo AChE reactivator against the broadest spectrum of nerve agents.
C1 [Shih, Tsung -Ming] USA, Med Res Inst Chem Def, ATTN MCMR CDR P, Pharmacol Branch,Res Div, Aberdeen Proving Ground, MD 21010 USA.
RP Shih, TM (reprint author), USA, Med Res Inst Chem Def, ATTN MCMR CDR P, Pharmacol Branch,Res Div, 3100 Ricketts Point Rd, Aberdeen Proving Ground, MD 21010 USA.
EM tsungming.a.shih@us.army.mil
FU Defense Threat Reduction Agency-Joint Service and Technology Office,
Medical Science and Technology Division
FX The authors recognized the excellent technical assistance of Laura
Gildner, Megan Lyman, Emily Mason, Maura Pannell, and Tami Rowland. This
research was supported by the Defense Threat Reduction Agency-Joint
Service and Technology Office, Medical Science and Technology Division.
NR 48
TC 25
Z9 28
U1 1
U2 3
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
SN 1537-6524
J9 TOXICOL MECH METHOD
JI Toxicol. Mech. Methods
PY 2009
VL 19
IS 6-7
BP 386
EP 400
DI 10.1080/15376510903213892
PG 15
WC Toxicology
SC Toxicology
GA 502JW
UT WOS:000270456100002
PM 19778239
ER
PT B
AU Howell, RA
Weerasooriya, T
Van Aken, DC
AF Howell, R. A.
Weerasooriya, T.
Van Aken, D. C.
GP American Foundry Society
TI Tensile, High Strain Rate Compression and Microstructural Evaluation of
Lightweight Age Hardenable Cast Fe-30Mn-9Al-XSi-0.9C-0.5Mo Steel
SO TRANSACTIONS OF THE AMERICAN FOUNDRY SOCIETY, VOL 117
SE Transactions of the American Foundry Society
LA English
DT Proceedings Paper
CT 113th Metalcasting Congress
CY APR 07-10, 2009
CL Las Vegas, NV
SP Amer Foundry Soc
ID AL-C ALLOYS; PHASE-TRANSFORMATIONS; MECHANICAL-PROPERTIES; AUSTENITIC
STEELS; SI
AB Age hardenable, castable, and lightweight Fe-Mn-Al-C steels are currently being developed and evaluated for substitution of high strength low alloy steel and to meet MIL-PRF-32269 criteria. Two nominal Fe-30Mn-9Al-0.9C-0.5Mo steels were cast and modified with 1 and 1.4 wt.% silicon. Ageing, tensile, and high strain rate compression testing were performed on solution treated and aged samples of both chemistries. Each alloy was solution treated at 1050 C for 2 hours. Microstructures of the solution treated and aged alloys show primary austenite with less than 8 volume % ferrite. The solution treated hardness of the low silicon steel was 230 BHN and the high silicon alloy was 225 BHN. Specimens were aged at 530 C for up to 60 hours. Peak ageing occurs after 30 hours with a peak hardness of 371 BHN for the 1%o silicon containing alloy and 377 BHN for the high silicon alloy. Tensile strengths of the 30 hour aged specimens were 1065 MPa (154 ksi) and 1080 MPa (156 ksi) for the low and high silicon alloys. High strain rate compression testing was conducted on solution treated and 10 hour aged 1% Si containing alloy. Compressive strength of the 1 wt.% Si alloy exceeded 1,500 MPa (217 ksi) at a strain rate of 3000 s(-1).
C1 [Howell, R. A.; Weerasooriya, T.] USA, Res Lab, Aberdeen Proving Ground, MD USA.
RP Howell, RA (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD USA.
NR 26
TC 11
Z9 11
U1 1
U2 2
PU AMER FOUNDRY SOCIETY, INC
PI SCHAUMBURG
PA 1695 N PENNY LANE, SCHAUMBURG, IL 60173 USA
BN 978-0-87433-340-4
J9 TRAN AMER F
PY 2009
VL 117
BP 751
EP 763
PG 13
WC Metallurgy & Metallurgical Engineering
SC Metallurgy & Metallurgical Engineering
GA BMA20
UT WOS:000271639500063
ER
PT J
AU Al-Smadi, YM
Russell, K
Lee, WT
Sodhi, RS
AF Al-Smadi, Yahia M.
Russell, Kevin
Lee, Wen-Tzong
Sodhi, Raj S.
TI AN EXTENSION OF AN ALGORITHM FOR PLANAR FOUR-BAR PATH GENERATION WITH
OPTIMIZATION
SO TRANSACTIONS OF THE CANADIAN SOCIETY FOR MECHANICAL ENGINEERING
LA English
DT Article
ID MOTION GENERATION; MECHANISMS; LINKAGES
AB This work is an extension of the authors' published work on a planar four-bar motion generation search algorithm with Grashof, transmission angle and linkage perimeter conditions [1]. This latest work considers planar four-bar path generation with a coupler point load, crank static torque, crank transverse deflection and follower buckling in a modified search algorithm. As demonstrated in the example, a conventional methodology used in kinematic path generation has been expanded to consider static loading, elastic deflection and buckling in path. generation. These factors must be considered in mechanical design, but are not the focus in traditional kinematic synthesis.
C1 [Al-Smadi, Yahia M.] AECOM Special Struct Grp, New York, NY 10005 USA.
[Russell, Kevin] USA, Res Dev & Engn Ctr, Armaments Engn & Technol Ctr, Picatinny Arsenal, NJ 07806 USA.
[Lee, Wen-Tzong] Leader Univ, Dept Comp Sci & Applicat, Tainan 70970, Taiwan.
[Sodhi, Raj S.] New Jersey Inst Technol, Dept Mech Engn, Newark, NJ 07102 USA.
RP Al-Smadi, YM (reprint author), AECOM Special Struct Grp, New York, NY 10005 USA.
EM yahia.al-smadi@aecom.com
NR 21
TC 2
Z9 2
U1 0
U2 0
PU CSME TRANS.
PI MONTREAL
PA C/O P J ZSOMBOR-MURRAY, MC GILL UNIV, RM 454 THOMAS WORKMAN ENG BLDG 817
SHERBROOKE ST W, MONTREAL, PQ H3A 2K6, CANADA
SN 0315-8977
J9 T CAN SOC MECH ENG
JI Trans. Can. Soc. Mech. Eng.
PY 2009
VL 33
IS 3
BP 443
EP 458
PG 16
WC Engineering, Mechanical
SC Engineering
GA 542CJ
UT WOS:000273468700007
ER
PT J
AU Jersey, SR
Edwards, L
AF Jersey, Sarah R.
Edwards, Lulu
TI Stiffness-Based Assessment of Pavement Foundation Materials Using
Portable Tools
SO TRANSPORTATION RESEARCH RECORD
LA English
DT Article
ID DEFLECTOMETER
AB Traditional pavement quality assurance has focused on soil density and moisture content. Implementation of new mechanistic design methods calls for measuring the resilient modulus of constructed layers to determine whether it matches the modulus used during the pavement design process. Several tools have been marketed for this purpose in recent years. Eleven soil test beds were constructed at the U.S. Army Engineer Research and Development Center to evaluate three of these tools. The study showed that the tools were simple to use and generally obtained repeatable results, but additional information regarding the true nature of the modulus measured by these tools was required to implement their use.
C1 [Jersey, Sarah R.; Edwards, Lulu] USA, Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA.
RP Jersey, SR (reprint author), USA, Engineer Res & Dev Ctr, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA.
EM sarah.r.jersey@usace.army.mil
NR 16
TC 1
Z9 1
U1 0
U2 2
PU NATL ACAD SCIENCES
PI WASHINGTON
PA 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA
SN 0361-1981
J9 TRANSP RES RECORD
JI Transp. Res. Record
PY 2009
IS 2116
BP 26
EP 34
DI 10.3141/2116-04
PG 9
WC Engineering, Civil; Transportation; Transportation Science & Technology
SC Engineering; Transportation
GA 536TL
UT WOS:000273066600004
ER
PT J
AU Alexander, DR
Gilbert, RB
AF Alexander, Don R.
Gilbert, Robert B.
TI Infrastructure Assessment Decision Making During a Crisis
SO TRANSPORTATION RESEARCH RECORD
LA English
DT Article
AB Engineers are being challenged to make critical decisions in response to crisis situations occurring around the globe on a seemingly daily basis. The nature of these crises varies widely and can include military missions as well as humanitarian operations in response to hurricanes, tsunamis, fires, and earthquakes. With thousands of lives hanging in the balance, timely and successful responses to these emergencies often depend on the optimal use of the existing horizontal infrastructure, such as roads, airfields, and railroads, in the affected area. Engineers must provide solutions quickly on the basis of limited data, particularly for unanticipated emergency situations. For military operations, options and alternatives are imperative to the success of a mission. This paper describes an analytical approach to the management of uncertainty because of limited data that provides a solution based on seasonal variability in material strengths, spatial variability in material strengths, and spatial variability in pavement layer thicknesses. An example scenario for an airfield is presented to illustrate techniques for analysis of the structural capacity of pavements of marginal quality and quantification of the uncertainty of the results.
C1 [Alexander, Don R.] USA, Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA.
[Gilbert, Robert B.] Univ Texas Austin, Dept Civil Engn, Cockrell Sch Engn, Austin, TX 78712 USA.
RP Alexander, DR (reprint author), USA, Engineer Res & Dev Ctr, 3909 Halls Ferry Rd CEERD GM R, Vicksburg, MS 39180 USA.
EM don.r.alexander@usace.army.mil
FU U.S. Army Engineer Research and Development Center (ERDC)
FX The authors gratefully acknowledge the support of the U.S. Army Engineer
Research and Development Center (ERDC) for providing financial support
for collaboration with the University of Texas at Austin.
NR 3
TC 0
Z9 0
U1 2
U2 3
PU NATL ACAD SCIENCES
PI WASHINGTON
PA 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA
SN 0361-1981
J9 TRANSP RES RECORD
JI Transp. Res. Record
PY 2009
IS 2093
BP 93
EP 98
DI 10.3141/2093-11
PG 6
WC Engineering, Civil; Transportation; Transportation Science & Technology
SC Engineering; Transportation
GA 527ZE
UT WOS:000272409000011
ER
PT J
AU Tingle, JS
Jersey, SR
AF Tingle, Jeb S.
Jersey, Sarah R.
TI Full-Scale Evaluation of Geosynthetic-Reinforced Aggregate Roads
SO TRANSPORTATION RESEARCH RECORD
LA English
DT Article
ID UNPAVED ROADS
AB A full-scale test section was constructed and trafficked by the US. Army Engineer Research and Development Center to evaluate the performance of geosynthetic reinforced aggregate road sections constructed with marginal base materials over a typical subgrade. Eight instrumented aggregate road sections-including three different aggregate base materials and two different geosynthetics-were constructed. The mechanistic response and permanent surface deformation of each pavement section were monitored at selected intervals during trafficking, and the data were analyzed to determine the benefit of using geotextiles or geogrids to reinforce aggregate roads. The test section's results indicated that the geosynthetics improved the performance of the reinforced pavement sections compared with unreinforced sections for all aggregate base materials. The mechanistic response in terms of surface deflection, deflection at the top of the subgrade, and vertical stress at the top of the subgrade was favorably consistent with the observed permanent deformation of the individual test items.
C1 [Tingle, Jeb S.; Jersey, Sarah R.] USA, Engineer Res & Dev Ctr, CEERD GM A, Vicksburg, MS 39180 USA.
RP Tingle, JS (reprint author), USA, Engineer Res & Dev Ctr, CEERD GM A, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA.
EM Jeb.S.Tingle@usace.army.mil
FU U.S. Army Engineering Research and Development Center, Waterways
Experiment Station; Chief of Engineers
FX The experiment described here, unless otherwise noted, was conducted
under the Lines-of-Communication program of the U.S. Army Corps of
Engineers by the U.S. Army Engineering Research and Development Center,
Waterways Experiment Station. Permission was granted by the Chief of
Engineers to publish this information.
NR 8
TC 3
Z9 3
U1 0
U2 5
PU NATL ACAD SCIENCES
PI WASHINGTON
PA 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA
SN 0361-1981
J9 TRANSP RES RECORD
JI Transp. Res. Record
PY 2009
IS 2116
BP 96
EP 107
DI 10.3141/2116-13
PG 12
WC Engineering, Civil; Transportation; Transportation Science & Technology
SC Engineering; Transportation
GA 536TL
UT WOS:000273066600013
ER
PT J
AU Priddy, LP
Jersey, SR
Freeman, RB
AF Priddy, Lucy P.
Jersey, Sarah R.
Freeman, Reed B.
TI Determining Rapid-Setting Material Suitability for Expedient Pavement
Repairs Full-Scale Traffic Tests and Laboratory Testing Protocol
SO TRANSPORTATION RESEARCH RECORD
LA English
DT Article
AB Numerous commercial off-the-shelf products have become available for small surface repairs in portland cement concrete (PCC) pavements, providing short set times, high early strengths, and good durability to withstand heavy loads. These materials have been used successfully for both small repairs in the transportation industry and industrial applications in which the repair was less than 0.03 m(3) (1 ft(3)). Applying these products for larger-volume repairs while still achieving a traffickable surface within 3 h of pavement repair has been a challenge. Experience gained from testing these products for full-depth repairs provides guidance for repair techniques that will expedite opening airfield or highway pavements to traffic and minimize the frequency of maintenance activities. An investigation conducted at the U.S. Army Engineer Research and Development Center, in Vicksburg, Mississippi, examined nine rapid-setting materials for repair of PCC pavements through laboratory characterization and full-scale traffic tests. Standard laboratory tests were performed to characterize the material properties over time and to provide a mechanism for assessing the material suitability for field repairs. Repairs with approximate volumes of 0.7 m(3) (1.5 yd(3)) were constructed and evaluated under controlled traffic conditions to determine the ability of the repairs to support 100 simulated passes of an F-15E aircraft within 3 h of repair. Results of traffic tests identified seven repair materials that met these criteria. A laboratory protocol for selection of rapid-setting materials was developed based on the laboratory and full-scale test results. Use of the protocol will help prevent the selection of materials that are unlikely to meet performance expectations.
C1 [Priddy, Lucy P.; Jersey, Sarah R.; Freeman, Reed B.] USA, Engineer Res & Dev Ctr, CEERD GM A, Vicksburg, MS 39180 USA.
RP Priddy, LP (reprint author), USA, Engineer Res & Dev Ctr, CEERD GM A, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA.
EM Lucy.p.priddy@usace.army.mil
NR 13
TC 4
Z9 4
U1 1
U2 2
PU NATL ACAD SCIENCES
PI WASHINGTON
PA 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA
SN 0361-1981
J9 TRANSP RES RECORD
JI Transp. Res. Record
PY 2009
IS 2113
BP 140
EP 148
DI 10.3141/2113-17
PG 9
WC Engineering, Civil; Transportation; Transportation Science & Technology
SC Engineering; Transportation
GA 536XJ
UT WOS:000273076900017
ER
PT J
AU Morales, W
Handschuh, RF
Krantz, TL
AF Morales, Wilfredo
Handschuh, Robert F.
Krantz, Timothy L.
TI Feasibility Study of Vapor-Mist Phase Reaction Lubrication using a
Thioether Liquid
SO TRIBOLOGY TRANSACTIONS
LA English
DT Article
DE Gears; Vapor Phase Lubrication
ID IRON
AB Aerospace drive systems are required to survive a loss-of-lubrication test for qualification. In many cases emergency lubrication systems need to be designed and utilized to permit the drive system to pass this difficult requirement. The weight of emergency systems can adversely affect the mission capabilities of the aircraft. The possibility to reduce the emergency system weight using vapor-mist phase lubrication (VMPL) technology has been considered by NASA and the Army Research Laboratory (ARL). Phosphate esters have been the lubricant of choice in most VMPL studies primarily because they do provide adequate lubrication for short periods of time. However, during the lubrication process, the phosphate esters react continuously with the surface iron in gears and bearings, resulting in excessive wear. To minimize this problem an alternative non-phosphate liquid, a thioether, was used to mist phase lubricate a spur gearbox rig operating at 10,000 rpm under highly loaded conditions. After 21 million shaft revolutions of operation the gears exhibited only minor wear.
C1 [Morales, Wilfredo] NASA, Glenn Res Ctr, Cleveland, OH 44135 USA.
[Handschuh, Robert F.; Krantz, Timothy L.] US Army Res Lab, Glenn Res Ctr, Cleveland, OH 44135 USA.
RP Morales, W (reprint author), NASA, Glenn Res Ctr, Cleveland, OH 44135 USA.
NR 11
TC 1
Z9 2
U1 0
U2 3
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
SN 1040-2004
J9 TRIBOL T
JI Tribol. Trans.
PY 2009
VL 52
IS 3
BP 370
EP 375
DI 10.1080/10402000802563448
PG 6
WC Engineering, Mechanical
SC Engineering
GA 424GS
UT WOS:000264554700004
ER
PT J
AU Sescu, A
Sescu, C
Dimofte, F
Cioc, S
Afjeh, AA
Handschuh, R
AF Sescu, Adrian
Sescu, Carmen
Dimofte, Florin
Cioc, Sorin
Afjeh, Abdollah A.
Handschuh, Robert
TI A Study of the Steady-State Performance of a Pressurized Air Wave
Bearing at Concentric Position
SO TRIBOLOGY TRANSACTIONS
LA English
DT Article
DE Air Bearings; Fluid Mechanics Methods; Turbulent Flow in Hydrodynamics
ID HYBRID JOURNAL BEARINGS; RESTRICTORS
AB The steady-state performance of a pressurized air wave bearing in concentric position is predicted using a commercial computational fluid dynamics (CFD) code. This code solves the three-dimensional compressible Navier-Stokes equations in the turbulent regime, taking into account the real geometry of both the bearing fluid film and the supply regions. The code can provide detailed information about the flow (pressure, turbulent kinetic energy distributions, velocity profiles, etc.) in all bearing regions including the supply holes. This approach does not involve a correction of the flow rate with an empirical discharge coefficient. The predicted values of the supply flow rates are compared to the experimental values obtained with a dedicated wave bearing test rig located at NASA Glenn Research Center in Cleveland, Ohio.
C1 [Sescu, Adrian; Sescu, Carmen; Dimofte, Florin; Cioc, Sorin; Afjeh, Abdollah A.] Univ Toledo, MIME Dept, Toledo, OH 43606 USA.
[Handschuh, Robert] USA, Res Lab, Cleveland, OH 44135 USA.
RP Sescu, A (reprint author), Univ Toledo, MIME Dept, 2801 W Bancroft St,MS 312, Toledo, OH 43606 USA.
NR 24
TC 6
Z9 6
U1 0
U2 5
PU TAYLOR & FRANCIS INC
PI PHILADELPHIA
PA 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
SN 1040-2004
J9 TRIBOL T
JI Tribol. Trans.
PY 2009
VL 52
IS 4
BP 544
EP 552
DI 10.1080/10402000902774275
PG 9
WC Engineering, Mechanical
SC Engineering
GA 474JH
UT WOS:000268279100007
ER
PT B
AU Collamer, AN
Battafarano, DF
AF Collamer, Angelique N.
Battafarano, Daniel F.
BE Rossard, TP
TI Tumor Necrosis Factor Antagonist Induced Psoriatic Skin Lesions
SO TUMOR NECROSIS FACTOR
SE Cell Biology Research Progress
LA English
DT Article; Book Chapter
ID NEW-ONSET PSORIASIS; FACTOR-ALPHA ANTAGONISTS; TNF-ALPHA; PALMOPLANTAR
PUSTULOSIS; RHEUMATOID-ARTHRITIS; INFLIXIMAB TREATMENT; CROHNS-DISEASE;
CASE SERIES; CUTANEOUS MANIFESTATIONS; GUTTATE PSORIASIS
C1 [Collamer, Angelique N.; Battafarano, Daniel F.] Brooke Army Med Ctr, Dept Rheumatol, Ft Sam Houston, TX 78234 USA.
RP Collamer, AN (reprint author), Brooke Army Med Ctr, Dept Rheumatol, Ft Sam Houston, TX 78234 USA.
NR 78
TC 0
Z9 0
U1 0
U2 0
PU NOVA SCIENCE PUBLISHERS, INC
PI HAUPPAUGE
PA 400 OSER AVE, STE 1600, HAUPPAUGE, NY 11788-3635 USA
BN 978-1-60741-708-8
J9 CELL BIO RES PROG
PY 2009
BP 133
EP 141
PG 9
WC Biochemistry & Molecular Biology; Cell Biology; Immunology
SC Biochemistry & Molecular Biology; Cell Biology; Immunology
GA BPY76
UT WOS:000280375000005
ER
PT J
AU Fishman, B
Forest, JJF
AF Fishman, Brian
Forest, James J. F.
BE Normark, M
Ranstorp, M
TI WMD and the four dimensions of al-Qaeda
SO UNCONVENTIONAL WEAPONS AND INTERNATIONAL TERRORISM: CHALLENGES AND NEW
APPROACHES
SE Cass Series on Political Violence
LA English
DT Article; Book Chapter
C1 [Fishman, Brian; Forest, James J. F.] US Mil Acad, Combating Terrorism Ctr, West Point, NY 10996 USA.
RP Fishman, B (reprint author), US Mil Acad, Combating Terrorism Ctr, West Point, NY 10996 USA.
NR 28
TC 0
Z9 0
U1 0
U2 0
PU ROUTLEDGE
PI NEW YORK
PA 29 W 35TH ST, NEW YORK, NY 10001 USA
BN 978-0-203-88195-8
J9 CASS SER POLIT VIOLE
PY 2009
BP 29
EP 49
D2 10.4324/9780203881958
PG 21
WC International Relations; Political Science
SC International Relations; Government & Law
GA BMJ75
UT WOS:000272594700003
ER
PT S
AU Baran, D
Fung, N
Ho, S
Sherman, J
AF Baran, David
Fung, Nick
Ho, Sean
Sherman, James
BE Gerhart, GR
Gage, DW
Shoemaker, CM
TI Detecting and tracking humans using a man-portable robot
SO UNMANNED SYSTEMS TECHNOLOGY XI
SE Proceedings of SPIE
LA English
DT Proceedings Paper
CT Conference on Unmanned Systems Technology XI
CY APR 17-17, 2009
CL Orlando, FL
SP SPIE
DE human detection; human tracking; Packbot; image processing; man-portable
ID FEATURES
AB Large gains in the automation of human detection and tracking techniques have been made over the past several years. Several of these techniques have been implemented on larger robotic platforms, in order to increase the situational awareness provided by the platform. Further integration onto a smaller robotic platform that already has obstacle detection and avoidance capabilities would allow these algorithms to be utilized in scenarios that are not plausible for larger platforms, such as entering a building and surveying a room for human occupation with limited operator intervention.
However, transitioning these algorithms to a man-portable robot imparts several unique constraints, including limited power availability, size and weight restrictions, and limited processor ability. Many imaging sensors, processing hardware, and algorithms fail to adequately address one or more of these constraints.
In this paper, we describe the design of a payload suitable for our chosen man-portable robot, the iRobot Packbot. While the described payload was built for a Packbot, it was carefully designed in order to be platform agnostic, so that it can be used on any man-portable robot. Implementations of several existing motion and face detection algorithms that have been chosen for testing on this payload are also discussed in some detail.
C1 [Baran, David; Fung, Nick; Ho, Sean; Sherman, James] USA, Res Lab, Adelphi, MD 20783 USA.
RP Baran, D (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
NR 29
TC 0
Z9 0
U1 0
U2 0
PU SPIE-INT SOC OPTICAL ENGINEERING
PI BELLINGHAM
PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
SN 0277-786X
BN 978-0-8194-7598-5
J9 PROC SPIE
PY 2009
VL 7332
AR 733215
DI 10.1117/12.818813
PG 11
WC Computer Science, Artificial Intelligence; Computer Science, Information
Systems; Robotics; Optics
SC Computer Science; Robotics; Optics
GA BVS50
UT WOS:000292646300028
ER
PT S
AU O'Brien, BJ
Sadler, L
AF O'Brien, Barry J.
Sadler, Laurel
BE Gerhart, GR
Gage, DW
Shoemaker, CM
TI Implementation of Small Robot Autonomy in an Integrated Environment
SO UNMANNED SYSTEMS TECHNOLOGY XI
SE Proceedings of SPIE
LA English
DT Proceedings Paper
CT Conference on Unmanned Systems Technology XI
CY APR 17-17, 2009
CL Orlando, FL
SP SPIE
DE autonomous mobility; SUGV; architecture; robotics; obstacle detection;
obstacle avoidance; SLAM
AB The U. S. Army Research Laboratory's (ARL) Computational and Information Sciences Directorate (CISD) has long been involved in autonomous asset control, specifically as it relates to small robots. Over the past year, CISD has been making strides in the implementation of three areas of small robot autonomy, namely platform autonomy, Soldier-robot interface, and tactical behaviors. It is CISD's belief that these three areas must be considered as a whole in order to provide Soldiers with useful capabilities.
In addressing these areas, CISD has integrated a COTS LADAR into the head of an iRobot PackBot Explorer, providing ranging information with minimal disruption to the physical characteristics of the platform. Using this range data is an implementation of obstacle detection and avoidance (OD/OA), leveraged from an existing autonomy software suite, running on the platform's native processor. These capabilities will serve as the foundation of our targeted behavior-based control methodologies. The first behavior is guarded tele-operation that augments the existing ARL robotic control infrastructure. The second is the implementation of a multi-robot cooperative mapping behavior. Developed at ARL, collaborative simultaneous localization and mapping (CSLAM) will allow multiple robots to build a common map of an area, providing the Soldier operator with a singular view of that area.
This paper will describe the hardware and software integration of the LADAR sensor into the ARL robotic control system. Further, the paper will discuss the implementation of the small robot OD/OA and CSLAM software components performed by ARL, as well as results on their performance and benefits to the Soldier.
C1 [O'Brien, Barry J.; Sadler, Laurel] USA, Res Lab, Adelphi, MD 20783 USA.
RP O'Brien, BJ (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
NR 14
TC 1
Z9 1
U1 0
U2 0
PU SPIE-INT SOC OPTICAL ENGINEERING
PI BELLINGHAM
PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
SN 0277-786X
BN 978-0-8194-7598-5
J9 PROC SPIE
PY 2009
VL 7332
AR 73321U
DI 10.1117/12.818494
PG 10
WC Computer Science, Artificial Intelligence; Computer Science, Information
Systems; Robotics; Optics
SC Computer Science; Robotics; Optics
GA BVS50
UT WOS:000292646300047
ER
PT S
AU O'Brien, BJ
Karan, C
Young, SH
AF O'Brien, Barry J.
Karan, Cem
Young, Stuart H.
BE Gerhart, GR
Gage, DW
Shoemaker, CM
TI FOCU:S - Future Operator Control Unit: Soldier
SO UNMANNED SYSTEMS TECHNOLOGY XI
SE Proceedings of SPIE
LA English
DT Proceedings Paper
CT Conference on Unmanned Systems Technology XI
CY APR 17-17, 2009
CL Orlando, FL
SP SPIE
DE small robot; autonomy; OCU; touch-screen
AB The U.S. Army Research Laboratory's (ARL) Computational and Information Sciences Directorate (CISD) has long been involved in autonomous asset control, specifically as it relates to small robots. Over the past year, CISD has been making strides in the implementation of three areas of small robot autonomy, namely platform autonomy, Soldier-robot interface, and tactical behaviors. It is CISD's belief that these three areas must be considered as a whole in order to provide Soldiers with useful capabilities.
In addressing the Soldier-robot interface aspect, CISD has begun development on a unique dismounted controller called the Future Operator Control Unit: Soldier (FOCU:S) that is based on an Apple iPod Touch. The iPod Touch's small form factor, unique touch-screen input device, and the presence of general purpose computing applications such as a web browser combine to give this device the potential to be a disruptive technology.
Setting CISD's implementation apart from other similar iPod or iPhone-based devices is the ARL software that allows multiple robotic platforms to be controlled from a single OCU. The FOCU:S uses the same Agile Computing Infrastructure (ACI) that all other assets in the ARL robotic control system use, enabling automated asset discovery on any type of network. Further, a custom ad hoc routing implementation allows the FOCU:S to communicate with the ARL ad hoc communications system and enables it to extend the range of the network.
This paper will briefly describe the current robotic control architecture employed by ARL and provide short descriptions of existing capabilities. Further, the paper will discuss FOCU:S specific software developed for the iPod Touch, including unique capabilities enabled by the device's unique hardware.
C1 [O'Brien, Barry J.; Karan, Cem; Young, Stuart H.] USA, Res Lab, Adelphi, MD 20783 USA.
RP O'Brien, BJ (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
NR 14
TC 1
Z9 1
U1 0
U2 1
PU SPIE-INT SOC OPTICAL ENGINEERING
PI BELLINGHAM
PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
SN 0277-786X
BN 978-0-8194-7598-5
J9 PROC SPIE
PY 2009
VL 7332
AR 73320P
DI 10.1117/12.818495
PG 10
WC Computer Science, Artificial Intelligence; Computer Science, Information
Systems; Robotics; Optics
SC Computer Science; Robotics; Optics
GA BVS50
UT WOS:000292646300017
ER
PT S
AU Rogers, JR
Korpela, C
Quigley, K
AF Rogers, John R.
Korpela, Christopher
Quigley, Kevin
BE Gerhart, GR
Gage, DW
Shoemaker, CM
TI Ten-kilogram vehicle autonomous operations
SO UNMANNED SYSTEMS TECHNOLOGY XI
SE Proceedings of SPIE
LA English
DT Proceedings Paper
CT Conference on Unmanned Systems Technology XI
CY APR 17-17, 2009
CL Orlando, FL
SP SPIE
DE unmanned ground vehicle; robot; low-cost; autonomy; high-speed
AB A low-cost unmanned ground vehicle designed to benchmark high-speed performance is presented. The E-Maxx four-wheel-drive radio-controlled vehicle equipped with a Robostix controller is proposed as a low-cost, high-speed robotic platform useful for military operations. The vehicle weighs less than ten kilograms making it easily portable by one person. Keeping cost low is a major consideration in the design with the aim of providing a disposable military robot. The suitability of the platform was evaluated and results are presented. Commercial-Off-The-Shelf (COTS) upgrades to the basic vehicle are recommended for durability. A procedure was established for bird's-eye-view video recording to document vehicle dynamics. Driver/vehicle performance is quantified by entry velocity, exit velocity and total time through a 90 turn on low-friction terrain. A setup for measuring these values is presented. Expert drivers use controlled skidding to minimize time through turns and the long term goal of the project is to automate such expert behaviors. Results of vehicle performance under human control are presented and stand as a reference for future autonomy.
C1 [Rogers, John R.; Korpela, Christopher; Quigley, Kevin] US Mil Acad, West Point, NY 10996 USA.
RP Rogers, JR (reprint author), US Mil Acad, West Point, NY 10996 USA.
EM john.rogers@usma.edu
NR 13
TC 0
Z9 0
U1 0
U2 0
PU SPIE-INT SOC OPTICAL ENGINEERING
PI BELLINGHAM
PA 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
SN 0277-786X
BN 978-0-8194-7598-5
J9 PROC SPIE
PY 2009
VL 7332
AR 73321X
DI 10.1117/12.818199
PG 8
WC Computer Science, Artificial Intelligence; Computer Science, Information
Systems; Robotics; Optics
SC Computer Science; Robotics; Optics
GA BVS50
UT WOS:000292646300049
ER
PT J
AU Alving, CR
AF Alving, Carl R.
BE Barrett, ADT
Stanberry, LR
TI Vaccine Adjuvants
SO VACCINES FOR BIODEFENSE AND EMERGING AND NEGLECTED DISEASES
LA English
DT Article; Book Chapter
ID ALUMINUM-CONTAINING ADJUVANTS; TOLL-LIKE RECEPTORS; CYTOTOXIC
T-LYMPHOCYTES; PLASMODIUM-FALCIPARUM MALARIA; PROTEOSOME-INFLUENZA
VACCINE; HYDROPHILE-LIPOPHILE BALANCE; ANTHRAX PROTECTIVE ANTIGEN; WATER
LIPOSOMAL EMULSIONS; B SURFACE-ANTIGEN; DENDRITIC CELLS
AB It is widely believed that adjuvants are important, and in some cases critical, for the success of most modern vaccines, particularly for new types of vaccines that have highly purified or synthetic antigens. Although aluminum salts are the most commonly used type of adjuvant for human vaccines, they are weak adjuvants that have complex mechanisms that favor induction of antibodies rather than cellular immunity. Aluminum salts do have a long record of relative safety, but they are also often responsible for local reactions at the site of injection, particularly for reactions that are associated with subcutaneous administration. Adjuvant selection for human vaccines still relies strongly on direct empirical testing of candidate adjuvants for safety and efficacy in humans. However, principles of innate immunity have been developed that provide some guidance for rational selection of adjuvants. New forms of vaccine adjuvants that have been proposed for various vaccines feature oil-based emulsions; bacterial products, such as lipid A, heat-labile E. coli enterotoxin, or CpG nucleotides; viral products, such as virus-like particles; plant products, such as saponin derivatives; biodegradable particles, such as liposomes; molecular adjuvants; and synthetic adjuvants. Adjuvant mechanisms include depot effects, recruitment of innate immunity mechanisms, specific targeting mechanisms, and carrier functions that hold the antigen in an appropriate conformation. The safety of proposed adjuvants is a primary consideration, and for this purpose it is often necessary to devise methods to reduce or eliminate the reactogenic effects of an adjuvant while preserving the efficacy. The most effective use of adjuvants for certain types of vaccines, particularly for stimulating mucosal immunity, may be to combine the adjuvant with a particular mode of delivery, such as oral, intranasal, or transcutaneous immunization. Carriers that carry and combine both the adjuvant and the antigen in a single formulation can serve as the basis for creation of important formulations for improved vaccines.
C1 Walter Reed Army Inst Res, Dept Adjuvant & Antigen Res, Div Retrovirol, US Mil HIV Res Program, Rockville, MD USA.
RP Alving, CR (reprint author), Walter Reed Army Inst Res, Dept Adjuvant & Antigen Res, Div Retrovirol, US Mil HIV Res Program, Rockville, MD USA.
NR 136
TC 3
Z9 3
U1 1
U2 5
PU ELSEVIER ACADEMIC PRESS INC
PI SAN DIEGO
PA 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 USA
BN 978-0-08-091902-7
PY 2009
BP 115
EP 129
DI 10.1016/B978-0-12-369408-9.00009-3
PG 15
WC Public, Environmental & Occupational Health; Immunology; Infectious
Diseases
SC Public, Environmental & Occupational Health; Immunology; Infectious
Diseases
GA BCR60
UT WOS:000311106000011
ER
PT J
AU Vaughn, DW
Whitehead, SS
Durbin, AP
AF Vaughn, David W.
Whitehead, Stephen S.
Durbin, Anna P.
BE Barrett, ADT
Stanberry, LR
TI Dengue
SO VACCINES FOR BIODEFENSE AND EMERGING AND NEGLECTED DISEASES
LA English
DT Article; Book Chapter
ID T-CELL RESPONSES; NEUTRALIZING ANTIBODY-RESPONSE; RECOMBINANT VACCINIA
VIRUS; HUMAN ENDOTHELIAL-CELLS; DISSEMINATED INTRAVASCULAR COAGULATION;
CLINICAL LABORATORY RESPONSES; RESPIRATORY SYNCYTIAL VIRUS;
JAPANESE-ENCEPHALITIS-VIRUS; PERIPHERAL-BLOOD LEUKOCYTES; INTERFERON
GAMMA-PRODUCTION
AB Molecular evolution studies suggest that dengue virus (DENV) evolved 1000 years ago and entered a sustained human-mosquito cycle between 125 and 320 years ago. While it is unlikely that DENV would be used as a biothreat agent, DENV has emerged since World War II as the most important mosquito-borne viral pathogen infecting an estimated 100 million persons each year. Infection with any of the four DENV serotypes (DENV-1, 2, 3, and 4) can be inapparent, result in classic dengue fever with high fever, headache, eye pain and muscle ache, or progress at the time of defervescence to dengue hemorrhagic fever (DHF) characterized by hemorrhagic manifestations and plasma leakage that can lead to shock and death. The immunopathological mechanisms by which DENV causes the clinical features of DHF are intricate and include aberrant humoral and cellular immune responses. Previous DENV infections may predispose to more severe disease by the induction of enhancing antibody and cross-reactive T cells. Treatment is supportive relying upon careful fluid management which can be lifesaving. Prevention currently depends on vector control which has been largely unsuccessful. Several dengue vaccine candidates have advanced to clinical trials to include classically and molecularly attenuated live virus vaccines, chimeric vaccines using dengue and yellow fever virus backbones, and DNA vaccines. Whole virus inactivated and recombinant subunit vaccine candidates should soon enter into clinical testing. Live attenuated DENV vaccines offer the most promise in terms of broad, long-lasting protection, and although they are economical to produce, they may carry the risks of enhanced reactogenicity in recipients with preexisting flavivirus antibodies, adverse events among the immunocompromised, vaccine virus transmission by vector mosquitoes, and the risk of adventitious agents. Chimeric vaccine approaches use the same gene sequence for the nonstructural proteins for each of the four DENV serotypes avoiding the need for attenuating mutations in the structural genes and potentially reducing interference in the replication of the four virus vaccine components within the multivalent vaccine recipient. DNA vaccines, in combination with other approaches, may increase the complexity and effectiveness of the immune response. Whole inactivated virus approaches have been used successfully for other viral diseases, reduce interference issues in multivalent vaccines, and have protected nonhuman primates from viremia following challenge with wild-type virus. Recombinant subunit vaccines have also protected nonhuman primates from viremia and offer a more focused approach in an attempt to tailor antibody and cell-mediated immure responses. While pathogenesis studies seek to dissect immune responses in an attempt to avoid vaccine-related disease enhancement, these risks, which apply to all vaccine approaches, may need to be evaluated empirically.
C1 [Vaughn, David W.] USA, Mil Infect Dis Res Program, Med Res & Dev Command, Ft Detrick, MD USA.
[Whitehead, Stephen S.] NIAID, Infect Dis Lab, Bethesda, MD 20892 USA.
[Durbin, Anna P.] Johns Hopkins Bloomberg Sch Publ Hlth, Ctr Immunizat Res, Dept Int Hlth, Baltimore, MD USA.
RP Vaughn, DW (reprint author), USA, Mil Infect Dis Res Program, Med Res & Dev Command, Ft Detrick, MD USA.
NR 356
TC 1
Z9 1
U1 1
U2 3
PU ELSEVIER ACADEMIC PRESS INC
PI SAN DIEGO
PA 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 USA
BN 978-0-08-091902-7
PY 2009
BP 287
EP 324
PG 38
WC Public, Environmental & Occupational Health; Immunology; Infectious
Diseases
SC Public, Environmental & Occupational Health; Immunology; Infectious
Diseases
GA BCR60
UT WOS:000311106000021
ER
PT B
AU Hammerbeck, CD
Wahl-Jensen, V
Hooper, JW
AF Hammerbeck, Christopher D.
Wahl-Jensen, Victoria
Hooper, Jay W.
BE Barrett, ADT
Stanberry, LR
TI Hantavirus
SO VACCINES FOR BIODEFENSE AND EMERGING AND NEGLECTED DISEASES
LA English
DT Article; Book Chapter
ID SIN-NOMBRE-VIRUS; NECROSIS-FACTOR-ALPHA; KOREAN HEMORRHAGIC-FEVER;
TO-PERSON TRANSMISSION; NEUTRALIZING ANTIBODY-RESPONSE; ENDOTHELIAL-CELL
MIGRATION; PULMONARY-SYNDROME; HANTAAN-VIRUS; RENAL SYNDROME;
NUCLEOCAPSID PROTEIN
AB Hantaviruses are known to cause diseases of military and public health concern. The association of hantaviruses and war can be attributed to the fact that these viruses are carried by rodents and are transmitted to humans via rodent excreta. During sustained ground combat operations, human-rodent contact inevitably increases due to an increased number of personnel working and sleeping in the rodents' habitat, environmental disruption, and a breakdown in hygiene. During the Korean War, casualties caused by hantaviruses impacted military operations and spurred research aimed at identifying the etiological agent responsible for what was then known as Korean hemorrhagic fever, and developing countermeasures to prevent and treat the disease. This research resulted in the identification of multiple hantaviruses responsible for hemorrhagic fever with renal syndrome (HFRS), including Hantaan virus, Seoul virus, Dobrava virus, and Puumala virus. An ongoing effort to develop vaccines against these viruses has resulted in inactivated-virus vaccines that have been licensed in Asia. In addition, efforts to develop safe, effective molecular subunit vaccines against these viruses have shown promise. The only drug to show any clinical efficacy against HFRS is ribavirin used soon after the first symptoms of the disease. Ribavirin has not been licensed by the Food and Drug Administration (FDA) for use as a treatment for HFRS. The viruses associated with HFRS pose a relatively low threat as biological weapons because the viruses are difficult to grow to high titer, HFRS is not contagious, and the case-fatality rates range between 0.1% and 15%. However, starting in 1993, several previously unknown, highly pathogenic hantaviruses were discovered in the Americas. At least one of these viruses poses a substantial bioterrorism threat. Andes virus grows to levels ten times higher than the HFRS-associated hantaviruses, can spread from person to person under close-contact conditions, and is highly pathogenic (30-50% cases are fatal). Andes virus and several other newly emerging hantaviruses in the Americas are associated with rapid onset of pulmonary edema followed by cardiogenic shock. There are no vaccines or effective drugs to prevent or treat hantavirus pulmonary syndrome (HPS). Here, we review the viruses associated with HFRS and HPS with an emphasis on ongoing efforts to develop vaccines against these dangerous pathogens.
C1 [Hammerbeck, Christopher D.; Wahl-Jensen, Victoria; Hooper, Jay W.] USA, Med Res Inst Infect Dis, Div Virol, Ft Detrick, MD 21702 USA.
RP Hammerbeck, CD (reprint author), USA, Med Res Inst Infect Dis, Div Virol, Ft Detrick, MD 21702 USA.
OI Hooper, Jay/0000-0002-4475-0415
NR 249
TC 2
Z9 2
U1 0
U2 2
PU ELSEVIER ACADEMIC PRESS INC
PI SAN DIEGO
PA 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 USA
BN 978-0-08-091902-7; 978-0-12-369408-9
PY 2009
BP 379
EP 411
DI 10.1016/B978-0-12-369408-9.00023-8
PG 33
WC Public, Environmental & Occupational Health; Immunology; Infectious
Diseases
SC Public, Environmental & Occupational Health; Immunology; Infectious
Diseases
GA BCR60
UT WOS:000311106000025
ER
PT J
AU Venkatesan, M
Kaminski, RW
Ranallo, RT
AF Venkatesan, Malabi
Kaminski, Robert W.
Ranallo, Ryan T.
BE Barrett, ADT
Stanberry, LR
TI Shigellosis
SO VACCINES FOR BIODEFENSE AND EMERGING AND NEGLECTED DISEASES
LA English
DT Article; Book Chapter
ID O-SPECIFIC POLYSACCHARIDE; NF-KAPPA-B; ENTEROINVASIVE ESCHERICHIA-COLI;
VACCINE CANDIDATE STRAINS; SHIGA-BACILLUS DYSENTERY; III SECRETION
APPARATUS; LARGE VIRULENCE PLASMID; 2 ATTENUATING MARKERS; DELETED AROD
GENE; FORM-I ANTIGEN
AB Shigellosis is an acute, inflammatory gastrointestinal disease of humans and primates, characterized by diarrhea, fever, nausea, tenesmus, and often dysentery, which is excretion of bloody, small volume stool with mucus. It is caused by a gram-negative, nonmotile bacterium that is orally ingested in contaminated food and water. There are four major serogroups each with one or more serotypes that are differentiated by the structure of the LPS-linked O antigen. Shigella is a Category B pathogen and the ricin-like Shiga toxin produced by Shigella dysenteriae 1 strains can cause significant toxicity and sometimes hemolytic uremic syndrome which can be fatal. All virulent strains of Shigella carry a large nonconjugative similar to 220 kb plasmid, which encodes determinants that induce a phagocytic uptake within the colonic epithelial layer. Invasion is followed by intercellular spread within the tissue, resulting in necrosis and release of proinflammatory cytokines and chemokines. Eventually this leads to an infiltration of neutrophils at the site of inflammation and resolution of infection. Shigella infections lead to systemic and mucosal responses that are primarily against the LPS O-antigen polysaccharide. Hence, immunity is serotype-specific although some responses are also seen against the major plasmid-encoded invasion plasmid antigens. Over the last 50 years subunit vaccines based on presenting LPS to the mucosal system as well as live-attenuated noninvasive and invasive vaccines have been tested in Phase I and field trials. Many lessons have been learnt from these trials and today, a more complete understanding of the molecular details of pathogenesis has helped to design specific mutated Shigella strains that have shown promise as live oral vaccine candidates. At the same time, novel ways of introducing the LPS antigen to the host strains are being evaluated as subunit vaccine candidates with significant success. Currently, only a single live, noninvasive bivalent Shigella vaccine exists in China which provides similar to 60% efficacy in adults. In the next few years a mixture of the current crop of vaccine candidates, both live and subunit, as well as combinations of the two types of vaccines will undergo testing in Phase I, II, and possibly Phase III trials. Data from these studies is expected to provide for a safe and effective vaccine development strategy that will protect against the predominant circulating serotypes of Shigella seen worldwide.
C1 [Venkatesan, Malabi; Kaminski, Robert W.; Ranallo, Ryan T.] Walter Reed Army Inst Res, Dept Pediat, Div Bacterial & Rickettsial Dis, Silver Spring, MD USA.
RP Venkatesan, M (reprint author), Walter Reed Army Inst Res, Dept Pediat, Div Bacterial & Rickettsial Dis, Silver Spring, MD USA.
NR 222
TC 0
Z9 0
U1 1
U2 2
PU ELSEVIER ACADEMIC PRESS INC
PI SAN DIEGO
PA 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 USA
BN 978-0-08-091902-7
PY 2009
BP 1163
EP 1192
DI 10.1016/B978-0-12-369408-9.00058-5
PG 30
WC Public, Environmental & Occupational Health; Immunology; Infectious
Diseases
SC Public, Environmental & Occupational Health; Immunology; Infectious
Diseases
GA BCR60
UT WOS:000311106000060
ER
PT J
AU Richie, TL
Parekh, FK
AF Richie, Thomas L.
Parekh, Falgunee K.
BE Barrett, ADT
Stanberry, LR
TI Malaria
SO VACCINES FOR BIODEFENSE AND EMERGING AND NEGLECTED DISEASES
LA English
DT Article; Book Chapter
ID PLASMODIUM-FALCIPARUM MALARIA; BLOOD-STAGE MALARIA; MEROZOITE SURFACE
PROTEIN-3; APICAL MEMBRANE ANTIGEN-1; YOELII CIRCUMSPOROZOITE PROTEIN;
HUMORAL IMMUNE-RESPONSES; GLUTAMATE-RICH PROTEIN; VACCINIA VIRUS ANKARA;
PRIME-BOOST IMMUNIZATION; DUFFY-BINDING-PROTEIN
AB Malaria is the most important parasitic disease with its vast distribution across the tropics and subtropics, immense public health burden, and tremendous economic impact on affected populations. Efforts to control malaria are being conducted on multiple fronts including vector control through residual house spraying, distribution of insecticide-treated bednets and improved diagnosis and treatment, including the development of new drugs and drug combinations effective against resistant strains. Despite these efforts, malaria remains prevalent in at least 87 countries with approximately 40% of the world's population living at risk; the greatest burden of malaria falls on young children with one child dying from malaria every 30s. Civil disturbance, inadequate health infrastructure, and poverty contribute to the lack of effective control. Experience with other infections such as smallpox, measles, and polio demonstrates that vaccines can be a highly effective and cost-efficient method of controlling an infectious agent with global impact.
The complexity of the malarial parasite has made the task of developing an efficacious vaccine difficult. Malaria is a vector-borne disease caused by a protozoan parasite of the genus Plasmodium, and transmitted by the bite of an Anopheles mosquito. The Plasmodium parasite has a complex life cycle with multiple stages, differential expression of antigens with each stage, and a high degree of antigenic variability. Additionally, unlike smallpox, measles, and many other infectious agents, protective immunity develops slowly, requires repeated infections, is never strong enough to prevent reinfection, and is quickly lost in the absence of exposure. Despite these challenges, there are two models of immunity that support the feasibility of developing a malaria vaccine: (1) immunization with radiation-attenuated sporozoites, which induces sterile protection against the sporozoite and liver stages of the parasite and (2) naturally acquired immunity, which is characterized by partial protection against the asexual blood stages. These models provide the basis for many of the malaria vaccine candidates currently under development, including vaccines designed to prevent infection (targeting sporozoite and liver stages) or to prevent disease (targeting blood stages). In addition, the sexual stages of the parasite can be targeted by vaccines designed to prevent transmission, an intriguing approach aimed at communitywide as opposed to individual benefit.
Currently, over 50 malaria vaccine candidates have reached various stages of clinical development. Most are subunit vaccines based on one or few antigens, and target one particular stage of the parasite life cycle. The subunit vaccines are constructed using a variety of platforms, including synthetic peptides or recombinant protein in adjuvant, viral vectors, DNA plasmids, and prime-boost combinations of these platforms. As it has become more apparent that a single antigen may not be sufficient to induce strong protective immunity against such a complex organism, a multiantigen, multistage approach is also being explored. More recently, there is focus on the attenuated whole parasite approach, which precludes the need to identify the antigens or immune mechanisms associated with protection.
This chapter will provide a summary of the history, biology, epidemiology, and clinical pathology of this important disease, and will then review progress in developing an effective malaria vaccine for widespread use.
C1 [Richie, Thomas L.; Parekh, Falgunee K.] USN, US Mil Malaria Vaccine Program, Med Res Ctr, Walter Reed Army Inst Res, Silver Spring, MD USA.
RP Richie, TL (reprint author), USN, US Mil Malaria Vaccine Program, Med Res Ctr, Walter Reed Army Inst Res, Silver Spring, MD USA.
OI Richie, Thomas/0000-0002-2946-5456
NR 489
TC 2
Z9 2
U1 4
U2 14
PU ELSEVIER ACADEMIC PRESS INC
PI SAN DIEGO
PA 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 USA
BN 978-0-08-091902-7
PY 2009
BP 1309
EP 1364
DI 10.1016/B978-0-12-369408-9.00065-2
PG 56
WC Public, Environmental & Occupational Health; Immunology; Infectious
Diseases
SC Public, Environmental & Occupational Health; Immunology; Infectious
Diseases
GA BCR60
UT WOS:000311106000067
ER
PT J
AU McCary, JA
AF McCary, John A.
TI The Anbar Awakening: An Alliance of Incentives
SO WASHINGTON QUARTERLY
LA English
DT Article
C1 USA, Washington, DC 20310 USA.
RP McCary, JA (reprint author), USA, Washington, DC 20310 USA.
EM john@writtenlife.com
NR 31
TC 19
Z9 19
U1 0
U2 3
PU ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXFORDSHIRE, ENGLAND
SN 0163-660X
J9 WASH QUART
JI Wash. Q.
PD JAN
PY 2009
VL 32
IS 1
BP 43
EP 59
PG 17
WC International Relations; Law
SC International Relations; Government & Law
GA 387CK
UT WOS:000261929100003
ER
PT J
AU Foster, JR
AF Foster, J. R.
TI Do Texas groundwater conservation districts matter?
SO WATER POLICY
LA English
DT Article
DE Fixed effects; Groundwater conservation districts; Groundwater
depletion; Panel data
ID PROPERTY-RIGHTS REGIME; EXHAUSTIBLE RESOURCES; COMMON PROPERTY; PRIVATE;
MANAGEMENT; ECONOMICS; AQUIFER; SYSTEM; POLICY; WATER
AB Texas faces a number of issues in an attempt to balance the water needs of a growing population while at the same time trying to conserve its water resources. Some of these issues include infrastructure improvements and provision of new supplies, changing patterns of use, water marketing and aquifer depletion. With aquifers providing 60% of all the water used in Texas, protecting and keeping these sources viable in the future is a key priority in addressing the state's water issues. With the state's emphasis on local control and the existence of between 80 and 90 groundwater districts state-wide, this research seeks to answer the question "Do groundwater districts in the State of Texas make a difference in groundwater depletion?" We use panel data from a set of 8,110 observations in a fixed effects regression to help us answer this question. We find evidence to suggest that groundwater districts do make a difference. After taking into consideration a couple of potential threats to validity, we run our model on a per district basis and by groundwater management areas. We also run it on a per aquifer basis and compare results with recommendations in the 2007 Texas Water Plan as a reality check. If we successfully answer the question that districts do in fact matter, the next logical step is to investigate what it is that districts do that makes a difference.
C1 [Foster, J. R.] Univ Texas Dallas, Sch Econ Polit & Policy Sci, Richardson, TX 75083 USA.
[Foster, J. R.] USA, Corps Engineers, Planning Branch, Ft Worth, TX 76102 USA.
RP Foster, JR (reprint author), Univ Texas Dallas, Sch Econ Polit & Policy Sci, Richardson, TX 75083 USA.
EM Jodie.R.Foster@usace.army.mil
NR 35
TC 0
Z9 0
U1 0
U2 4
PU I W A PUBLISHING
PI LONDON
PA ALLIANCE HOUSE, 12 CAXTON ST, LONDON SW1H0QS, ENGLAND
SN 1366-7017
J9 WATER POLICY
JI Water Policy
PY 2009
VL 11
IS 3
BP 379
EP 399
DI 10.2166/wp.2009.015
PG 21
WC Water Resources
SC Water Resources
GA 456XH
UT WOS:000266885700008
ER
PT S
AU Ashby, S
Richards, D
Wallace, R
AF Ashby, S.
Richards, D.
Wallace, R.
BE Brebbia, CA
Popov, V
TI Simple to complex tools for sustainable water resource management
SO WATER RESOURCES MANAGEMENT V
SE WIT Transactions on Ecology and the Environment
LA English
DT Proceedings Paper
CT 5th International Conference on Sustainable Water Resources Management
CY SEP 09-11, 2009
CL MALTA
SP Wessex Inst Technol, WIT Transact Ecol & Environm
DE watersheds; geospatial; modeling; habitat; visualization
AB The U.S. Army Corps of Engineers has developed a system of tools to improve environmental forecasting and decision-making in comprehensive water resources management. Currently available tools include geospatial assessment techniques, habitat and index-based models, single- and multi-dimensional numerical models, and ecological models based on concepts of bioenergetics, individual-based response, and trophic structure. Applications of these models for sustainable water resource management provide opportunities to assess and predict landscape changes, owing to activities such as urbanization, ecosystem restoration, water resource project operations, etc. at various temporal and spatial scales. Since resources (e.g., data, time, expertise, funding, etc) are often limited, a tiered or hierarchical approach to water resources management is recommended. For example, geospatial technologies can be used to develop land cover and land use data layers for applications in habitat-based models or numerical models for watershed runoff predictions. Index-based models can be used in conjunction with stakeholder-developed performance criteria to forecast potential adaptive management trajectories for sustained and multi-purpose use of water resources. Another level of water resource assessment combines predictions of land use changes and subsequent changes in material loadings with potential biological response in aquatic systems using multi-dimensional models. This suite of tools has been developed within a framework to "customize" comprehensive tool selection in the decision-making process, thus ultimately allowing user communities to maintain databases, conduct alternative analyses, and transfer information in a user-friendly format. Selected case study applications are presented to demonstrate this concept.
C1 [Ashby, S.; Richards, D.; Wallace, R.] USA, Engineer Res & Dev Ctr, Washington, DC USA.
RP Ashby, S (reprint author), USA, Engineer Res & Dev Ctr, Washington, DC USA.
NR 5
TC 0
Z9 0
U1 1
U2 5
PU WIT PRESS
PI SOUTHAMPTON
PA ASHURST LODGE, SOUTHAMPTON SO40 7AA, ASHURST, ENGLAND
SN 1743-3541
BN 978-1-84564-199-3
J9 WIT TRANS ECOL ENVIR
PY 2009
VL 125
BP 47
EP 54
DI 10.2495/WRM090051
PG 8
WC Ecology; Environmental Sciences; Water Resources
SC Environmental Sciences & Ecology; Water Resources
GA BMM56
UT WOS:000272819300005
ER
PT J
AU Wilson, DK
Ostashev, VE
Lewis, MS
AF Wilson, D. Keith
Ostashev, Vladimir E.
Lewis, Matthew S.
TI Moment-screen method for wave propagation in a refractive medium with
random scattering
SO WAVES IN RANDOM AND COMPLEX MEDIA
LA English
DT Article
ID RANDOM INTERNAL WAVES; SOUND-PROPAGATION; PARABOLIC-EQUATION; TURBULENT
ATMOSPHERE; OCEAN; FIELD; MODEL; FLUCTUATIONS; STATISTICS; GUIDE
AB Direct numerical solution of a parabolic equation (PE) for the second moment of the sound field in a refracting medium with random scattering is described. The method determines the mean-square sound pressure without requiring generation of random realizations of the propagation medium. The second-moment matrix is factored into components that are independently propagated with a conventional PE algorithm. A moment screen is periodically applied to attenuate the coherence of the wavefield, much as phase screens are often applied in the method of random realizations. An example involving upwind and downwind propagation in the near-ground atmosphere shows that the new direct method converges to an accurate solution faster than the method of random realizations and is particularly well suited to calculations at low frequencies.
C1 [Wilson, D. Keith; Lewis, Matthew S.] USA, Engineer Res & Dev Ctr, Hanover, NH 03755 USA.
[Ostashev, Vladimir E.] NOAA, Earth Syst Res Lab, Boulder, CO 80305 USA.
[Ostashev, Vladimir E.] New Mexico State Univ, Dept Phys, Las Cruces, NM 88003 USA.
RP Wilson, DK (reprint author), USA, Engineer Res & Dev Ctr, Hanover, NH 03755 USA.
EM d.keith.wilson@usace.army.mil
RI Wilson, D. Keith/A-4687-2012
OI Wilson, D. Keith/0000-0002-8020-6871
FU US Army Engineer Research and Development Center
FX This research was sponsored by the US Army Engineer Research and
Development Center. We thank the reviewers for their insightful comments
on the initial version of this article.
NR 24
TC 4
Z9 4
U1 0
U2 0
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
SN 1745-5030
J9 WAVE RANDOM COMPLEX
JI Waves Random Complex Media
PY 2009
VL 19
IS 3
BP 369
EP 391
AR PII 910562379
DI 10.1080/17455030802647462
PG 23
WC Physics, Multidisciplinary
SC Physics
GA 558NO
UT WOS:000274750800001
ER
PT J
AU Tong, MS
Ting, LY
Chew, WC
White, MJ
AF Tong, Mei Song
Ting, Leon Yeow
Chew, Weng Cho
White, Michael J.
TI A study for sound wave scattering by corrugated ground with complex
trench structures
SO WAVES IN RANDOM AND COMPLEX MEDIA
LA English
DT Article
ID BLAST NOISE; LARGE FIREARMS; SNOW COVER; PROPAGATION; PREDICTION;
ATMOSPHERE; REDUCTION; SURFACES; ARTILLERY; IMPEDANCE
AB Several trench structures in corrugated ground are investigated for the possibility of mitigating gun blast noise by numerical simulations. The blast noise usually includes large explosive energy with nonlinearity in the near field and exhibits a very low-frequency spectrum. In this study, the linearity approximation for the noise is taken because the nonlinearity of the wave reaching the scatterer is not serious for many proved guns and the low-frequency characteristic is concentrated. The structures are designed based on the surface impedance design approach proposed in our previous work and arbitrary three-dimensional (3D) geometries within a truncated ground are now assumed. The acoustic characteristic of the structures is evaluated by using a fast numerical solver. The solver employs the multilevel fast multipole algorithm (MLFMA) as an accelerator and can solve very large acoustic wave scattering problems with millions of unknowns on workstations within several days. This tool allows us to truncate the ground as large as needed for accurate modeling. Four structures are mainly considered in the design, namely, concentric trenches, sectorial trapezoidal trenches, interlaced arc trenches and parabolic reflectors. Some of them may have a sloped inner wall or tilted surface as a means of adjustment. Numerical simulations show that the concentric trench design has a very good mitigation behavior for linear and continuous noise sources and the structure is further studied for mitigating real-world gun blast noise.
C1 [Tong, Mei Song; Ting, Leon Yeow; Chew, Weng Cho] Univ Illinois, Dept Elect & Comp Engn, Urbana, IL 61801 USA.
[White, Michael J.] US Army Corps Engineers, Engn Res & Dev Ctr, Construct Engn Res Lab, Champaign, IL 61826 USA.
RP Chew, WC (reprint author), Univ Illinois, Dept Elect & Comp Engn, 1406 W Green St, Urbana, IL 61801 USA.
EM w-chew@uiuc.edu
RI White, Michael/B-3612-2009; Chew, Weng Cho/C-1792-2009
OI White, Michael/0000-0001-8450-9135;
FU Construction Engineering Research Laboratory (CERL), US Army
[W9132T-06-2-0006]
FX This work was supported by Construction Engineering Research Laboratory
(CERL), US Army, under the grant W9132T-06-2-0006.
NR 39
TC 0
Z9 0
U1 0
U2 3
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
SN 1745-5030
J9 WAVE RANDOM COMPLEX
JI Waves Random Complex Media
PY 2009
VL 19
IS 3
BP 392
EP 408
AR PII 910562218
DI 10.1080/17455030902725630
PG 17
WC Physics, Multidisciplinary
SC Physics
GA 558NO
UT WOS:000274750800002
ER
PT J
AU Ostashev, VE
Collier, SL
Wilson, DK
AF Ostashev, Vladimir E.
Collier, Sandra L.
Wilson, D. Keith
TI Transverse-longitudinal coherence function of a sound field for
line-of-sight propagation in a turbulent atmosphere
SO WAVES IN RANDOM AND COMPLEX MEDIA
LA English
DT Article
ID WAVES; PLANE; PERFORMANCE; ARRAYS
AB Using the narrow-angle and Markov approximations, a formula for the transverse-longitudinal coherence function of a sound field propagating in a turbulent atmosphere with temperature and wind velocity fluctuations is derived. This function, which applies to observation points that are arbitrarily located in space, generalizes the transverse coherence function (coherence when the observation points are in a plane perpendicular to the sound propagation path), which has been studied extensively. The new result is expressed in terms of the transverse coherence function and the extinction coefficient of the mean sound field. The transverse-longitudinal coherence function of a plane sound wave is then calculated and studied in detail for the Gaussian and von Karman spectra of temperature and wind velocity fluctuations. It is shown, for relatively small propagation distances, that the magnitude of the coherence function decreases in the longitudinal direction but remains almost constant in the transverse direction. On the other hand, for moderate and large propagation distances, the magnitude of the coherence decreases faster in the transverse direction than in the longitudinal. For some parameters of the problem, the coherence function has relatively large local maxima and minima as the transverse and longitudinal coordinates are varied. With small modifications, many results obtained in the paper can be applied to studies of electromagnetic wave propagation in a turbulent atmosphere.
C1 [Ostashev, Vladimir E.] NOAA, Earth Syst Res Lab, Boulder, CO 80305 USA.
[Ostashev, Vladimir E.] New Mexico State Univ, Dept Phys, Las Cruces, NM 88003 USA.
[Collier, Sandra L.] USA, Res Lab, AMSRD ARL CI ES, Adelphi, MD 20783 USA.
[Wilson, D. Keith] USA, Engineer Res & Dev Ctr, Hanover, NH 03755 USA.
RP Ostashev, VE (reprint author), NOAA, Earth Syst Res Lab, 325 Broadway, Boulder, CO 80305 USA.
EM vladimir.ostashev@noaa.gov
RI Wilson, D. Keith/A-4687-2012
OI Wilson, D. Keith/0000-0002-8020-6871
NR 25
TC 2
Z9 2
U1 0
U2 1
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
SN 1745-5030
J9 WAVE RANDOM COMPLEX
JI Waves Random Complex Media
PY 2009
VL 19
IS 4
BP 670
EP 691
DI 10.1080/17455030903038504
PG 22
WC Physics, Multidisciplinary
SC Physics
GA 558NQ
UT WOS:000274751000006
ER
PT J
AU Mudge, CR
Haller, WT
AF Mudge, Christopher R.
Haller, William T.
TI Ornamental and Row Crop Susceptibility to Flumioxazin in Overhead
Irrigation Water
SO WEED TECHNOLOGY
LA English
DT Article
DE Aquatic; nontarget injury; herbicide injury; EC(10); effective
concentration 10
ID PEANUT ARACHIS-HYPOGAEA; WEED MANAGEMENT; PROTOPORPHYRINOGEN OXIDASE;
PLANT TOLERANCES; STRIP-TILLAGE; ENDOTHALL; HERBICIDES; FLURIDONE;
PREPLANT; DIQUAT
AB The effects of flumioxazin in irrigation water were evaluated on four row crop species (corn, cotton, soybean, and wheat) and three ornamental species (begonia, impatiens, and snapdragon). Plants were overhead irrigated one time with flumioxazin at concentrations of 0, 10, 25, 50, 100, 200, 400, 800, 1,600, and 3,200 mu g ai/L in water equivalent to 1.27 cm. Ornamental plant tolerances on the basis of a 10% reduction in dry weight (effective concentration 10 [EC(10)]) were as follows: impatiens (40) < begonia (103) < snapdragon (7,024). The EC(10) values of flumioxazin on the basis of dry weight values for row crop species were wheat (35) < corn experiment 1 (53) < cotton. (106) < corn experiment 2 (181) < soybean (193). EC(10) values for plant height were similar to values for plant dry weight for ornamental and crop species. Snapdragon was the only plant evaluated that was mature at the time of treatment; consequently, all other species were moderately to highly sensitive to irrigation water containing flumioxazin. These data show that flumioxazin can injure and kill immature ornamental and crop species within the potential maximum concentration of 400 mu g/L; however, the very short half-life of this herbicide in water with pH 7.0 to 9.0 (ca. 16 h to 17 min) could result in less injury than suggested in this study.
C1 [Mudge, Christopher R.; Haller, William T.] Univ Florida, Inst Food & Agr Sci, Ctr Aquat & Invas Plants, Gainesville, FL 32611 USA.
RP Mudge, CR (reprint author), USA, Engn Res & Dev Ctr, Vicksburg, MS 39180 USA.
EM Christopher.R.Mudge@usace.army.mil
FU Aquatic Ecosystem Restoration Foundation; Valent U.S.A. Corporation
FX We thank the Aquatic Ecosystem Restoration Foundation and Valent U.S.A.
Corporation for partial funding of this research.
NR 38
TC 3
Z9 3
U1 0
U2 4
PU WEED SCI SOC AMER
PI LAWRENCE
PA 810 EAST 10TH ST, LAWRENCE, KS 66044-8897 USA
SN 0890-037X
J9 WEED TECHNOL
JI Weed Technol.
PD JAN-MAR
PY 2009
VL 23
IS 1
BP 89
EP 93
DI 10.1614/WT-08-024.1
PG 5
WC Agronomy; Plant Sciences
SC Agriculture; Plant Sciences
GA 423CG
UT WOS:000264473400015
ER
PT B
AU Meghanathan, N
Milton, LC
AF Meghanathan, Natarajan
Milton, Leslie C.
GP IEEE
TI A Simulation Based Performance Comparison Study of Stability-Based
Routing, Power-Aware Routing and Load-Balancing On-Demand Routing
Protocols for Mobile Ad hoc Networks
SO WONS 2009: SIXTH INTERNATIONAL CONFERENCE ON WIRELESS ON-DEMAND NETWORK
SYSTEMS AND SERVICES
LA English
DT Proceedings Paper
CT 6th International Conference on Wireless On-Demand Network Systems and
Services
CY FEB 02-04, 2009
CL Snowbird, UT
AB The high-level contribution of this paper is a simulation-based detailed performance comparison of three different classes of on-demand routing protocols for mobile ad hoc networks: stability-based routing, power-aware routing and load-balanced routing. We choose the Flow-Oriented Routing protocol (FOR-P), Min-Max Battery Cost Routing (MMBCR) and the traffic interference based Load Balancing Routing (LBR) protocol as representatives of the stability-based routing, power-aware routing and load-balancing routing protocols respectively. FORP incurs the least number of route transitions; while LBR incurs the smallest hop count and lowest end-to end delay per data packet. Energy consumed per data packet is the least for LBR, closely followed by MMBCR. FORP incurs the maximum energy consumed per data packet, both in the absence and presence of power control. Nevertheless, in the presence of power control, the end-to-end delay per data packet and energy consumed per data packet incurred by FORP are significantly reduced compared to the scenario without power control. MMBCR is the most fair in terms of node usage and incurs the largest time for first node failure. FORP tends to repeatedly use nodes lying on the stable path and hence is the most unfair of the three routing protocols. FORP also incurs the smallest value for the time of first node failure.
C1 [Meghanathan, Natarajan] Jackson State Univ, Jackson, MS 39217 USA.
[Milton, Leslie C.] US Army, Engn Res & Dev Ctr, Vicksburg, MS 39180 USA.
RP Meghanathan, N (reprint author), Jackson State Univ, Jackson, MS 39217 USA.
EM nmeghanathan@jsums.edu; Leslie.C.Milton@usace.anny.mil
NR 20
TC 0
Z9 0
U1 2
U2 3
PU IEEE
PI NEW YORK
PA 345 E 47TH ST, NEW YORK, NY 10017 USA
BN 978-1-4244-3374-2
PY 2009
BP 1
EP +
PG 2
WC Computer Science, Hardware & Architecture; Engineering, Electrical &
Electronic; Telecommunications
SC Computer Science; Engineering; Telecommunications
GA BKQ21
UT WOS:000268929600001
ER
PT J
AU Rice, VJB
Mays, MZ
Gable, C
AF Rice, Valerie J. Berg
Mays, Mary Z.
Gable, Clayton
TI Self-reported health status of students in-processing into military
medical advanced individual training
SO WORK-A JOURNAL OF PREVENTION ASSESSMENT & REHABILITATION
LA English
DT Article
DE Musculoskeletal injury; risk factors; screening; stress; fitness
ID RISK-FACTORS; INJURIES; ARMY; EPIDEMIOLOGY; WOMEN; MEN
AB It is important to be aware of the health and injury status of students in military training settings in order to adequately plan for their progression through required physical training and provision of health care to meet their needs. This paper describes the self-reported health status of students arriving in two medical training Battalions at Ft. Sam Houston. The results revealed that 43% of arriving soldiers had musculoskeletal symptoms and 35% had symptoms that interfered with their ability to accomplish the normal daily activities required as students. The most common sites of symptoms were knee (17 and 18%), foot/toe (16 and 13%), ankle (9 and 10%), and lower leg (9 and 12%) for the 232(nd) and 187(th) Medical Battalions respectively. Risk factors for those with musculoskeletal injury (MSI) symptoms that interfere with their abilities to do their jobs include gender, past history of injury, and self-reported stress and fitness levels. Other risk factors for medical specialties other than combat medic include being older (over 24 yrs of age), active duty status, being overweight, and use of smokeless tobacco. This information can help identify soldiers considered at risk of incurring a MSI during AIT. With this knowledge, physical training can be designed to help soldiers achieve fitness without additional injury and health care facilities can be designed to provide appropriate staffing of the health care professionals needed for evaluation and treatment.
C1 [Rice, Valerie J. Berg] Army Med Dept Ctr, Human Res & Engn Directorate, Army Res Lab, Ft Sam Houston, TX 78234 USA.
[Rice, Valerie J. Berg] Sch Field Element, Ft Sam Houston, TX 78234 USA.
[Mays, Mary Z.] Arizona State Univ, Coll Nursing & Hlth Innovat, Phoenix, AZ USA.
[Gable, Clayton] Headquarters US Army Med Command, Hlth Policy & Serv, Behav Hlth Div, Army Cent Registry, Ft Sam Houston, TX USA.
RP Rice, VJB (reprint author), Army Med Dept Ctr, Human Res & Engn Directorate, Army Res Lab, 2421 FSH Hood St, Ft Sam Houston, TX 78234 USA.
EM Valerie.Rice@amedd.army.mil
NR 19
TC 1
Z9 1
U1 0
U2 2
PU IOS PRESS
PI AMSTERDAM
PA NIEUWE HEMWEG 6B, 1013 BG AMSTERDAM, NETHERLANDS
SN 1051-9815
J9 WORK
JI Work
PY 2009
VL 34
IS 4
BP 387
EP 400
DI 10.3233/WOR-2009-0939
PG 14
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 545SE
UT WOS:000273756200002
PM 20075516
ER
PT J
AU Rice, VJ
Vu, T
Butler, J
Marra, D
Merullo, D
Banderet, L
AF Rice, Valerie J.
Vu, Tan
Butler, Jenny
Marra, Diane
Merullo, Donna
Banderet, Louis
TI Fear of failure: Implications for military health care specialist
student training
SO WORK-A JOURNAL OF PREVENTION ASSESSMENT & REHABILITATION
LA English
DT Article
ID CLAIMED SELF-HANDICAPS; DEFENSIVE PESSIMISM; PERFORMANCE FAILURE;
APPRAISAL INVENTORY; MOTIVATION; ACHIEVEMENT; CONSEQUENCES; RESPONSES;
OPTIMISM; ANXIETY
AB During scholastic or physical performance testing, individuals who fear failure tend to focus on their fears instead of the task and often perform poorly. This study examined the relationship between fear-of-failure (FoF) and performance among 200 students (male = 140, female = 60) attending Health Care Specialist Advanced Individual Training (AIT) at Ft. Sam Houston. Performance measures included grade point average, pass/fail status, Army Physical Fitness Test scores, and number of musculoskeletal injuries. Pearson Product Moment Correlations revealed that Soldiers who scored higher on a FoF scale also had higher final grades (r = 0.16, p = 0.02, r(2) = 0.026). No significant correlations were found between FoF and other performance measures. While the variation in GPA accounted for by FoF was small (2.6%), this finding demonstrates a positive relationship that differs from previous studies. This finding may be explained by the concepts of failure avoidance and success orientation (self confidence and motivation), as well as the unique military setting. Suggestions for designing military educational interventions during AIT and throughout one's military career are offered.
C1 [Rice, Valerie J.] Army Med Dept Ctr, Human Res & Engn Directorate, Army Res Lab, Ft Sam Houston, TX 78234 USA.
[Rice, Valerie J.] Sch Field Element, Ft Sam Houston, TX 78234 USA.
[Merullo, Donna; Banderet, Louis] USA, Environm Med Res Inst, Washington, DC 20310 USA.
RP Rice, VJ (reprint author), Army Med Dept Ctr, Human Res & Engn Directorate, Army Res Lab, 1750 Greely Rd,STE 219, Ft Sam Houston, TX 78234 USA.
EM Valerie.Rice@amedd.army.mil
NR 38
TC 1
Z9 1
U1 1
U2 7
PU IOS PRESS
PI AMSTERDAM
PA NIEUWE HEMWEG 6B, 1013 BG AMSTERDAM, NETHERLANDS
SN 1051-9815
EI 1875-9270
J9 WORK
JI Work
PY 2009
VL 34
IS 4
BP 465
EP 474
DI 10.3233/WOR-2009-0947
PG 10
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 545SE
UT WOS:000273756200010
PM 20075524
ER
PT J
AU Shuping, E
Canham-Chervak, M
Amoroso, PJ
Jones, BH
AF Shuping, Eric
Canham-Chervak, Michelle
Amoroso, Paul J.
Jones, Bruce H.
TI Identifying modifiable causes of fall-related injury: An analysis of US
Army safety data
SO WORK-A JOURNAL OF PREVENTION ASSESSMENT & REHABILITATION
LA English
DT Article
DE Injury; epidemiology; occupational; falls; elevation; height; military;
safety
ID CONSTRUCTION FALLS; UNION CARPENTERS; PATTERNS; ALCOHOL; SLIPS; TEXT
AB Details on fall-related circumstances, a leading cause of occupational injury, are scarce. This study aimed to identify modifiable causes of falls using data from safety reports. Coded and narrative data on injured persons, event locations, and circumstances associated with falls sustained by U. S. Army personnel were obtained from safety reports dated September 1994 September 2002. Descriptive statistics are presented for injury outcomes and risk factors, with a focus on falls from elevation. On average, 59 fall-related injuries/100,000 person-years were reported. Higher rates occurred among whites, single persons, and 20-24 year-olds. Falls from elevation resulted in more severe outcomes, longer hospitalizations, and more lost work time compared to falls from the same level. Most falls from elevation occurred in training (32%) and housing (18%) areas. Leading causes included routine activities (e. g., walking, entering/exiting vehicles) (35%), physical training (12%), and sports (12%). Interventions to prevent falls from elevation in this population should focus on reducing risks from routine activities, specifically in training and housing areas. Safety reports provided details necessary for prioritizing and planning fall prevention efforts that are not available from other sources.
C1 [Shuping, Eric] Ireland Army Community Hosp, Ft Knox, KY 40121 USA.
[Canham-Chervak, Michelle; Jones, Bruce H.] USA, Ctr Hlth Promot & Prevent Med, Injury Prevent Program, Bethesda, MD USA.
[Amoroso, Paul J.] Madigan Army Med Ctr, Tacoma, WA 98431 USA.
RP Shuping, E (reprint author), Ireland Army Community Hosp, 851 Ireland Loop, Ft Knox, KY 40121 USA.
EM eric.e.shuping@us.army.mil
NR 37
TC 2
Z9 2
U1 0
U2 1
PU IOS PRESS
PI AMSTERDAM
PA NIEUWE HEMWEG 6B, 1013 BG AMSTERDAM, NETHERLANDS
SN 1051-9815
J9 WORK
JI Work
PY 2009
VL 33
IS 1
BP 23
EP 34
DI 10.3233/WOR-2009-0840
PG 12
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 480FD
UT WOS:000268716800004
PM 19597282
ER
PT J
AU Case, FH
Brennan, J
Chaka, A
Dobbs, KD
Friend, DG
Gordon, PA
Moore, JD
Mountain, RD
Olson, JD
Ross, RB
Schiller, M
Shen, VK
Stahlberg, EA
AF Case, Fiona H.
Brennan, John
Chaka, Anne
Dobbs, Kerwin D.
Friend, Daniel G.
Gordon, Peter A.
Moore, Jonathan D.
Mountain, Raymond D.
Olson, James D.
Ross, Richard B.
Schiller, Martin
Shen, Vincent K.
Stahlberg, Eric A.
TI The fourth industrial fluid properties simulation challenge
SO FLUID PHASE EQUILIBRIA
LA English
DT Article
DE Force field; Intermolecular potential; Molecular simulation; Simulation
challenge
ID MOLECULAR-DYNAMICS SIMULATION; VAPOR-LIQUID-EQUILIBRIA; HENRYS LAW
CONSTANTS; MONTE-CARLO SIMULATIONS; BUBBLE POINT PRESSURE;
ETHYLENE-OXIDE; FORCE-FIELD; ESTABLISHING BENCHMARKS; CARBON-DIOXIDE;
PREDICTION
AB The primary goal of the fourth industrial fluid properties simulation challenge was to test the transferability of molecular simulation methods and intermolecular potentials (force fields) when applied to a wide variety of physical properties for a given industrially relevant small molecule. Force field parameters are often developed for, tested with, and applied to a relatively limited range property types. Methods that are able to predict a broad range of properties may be more useful for practical application in an industrial setting. To address this primary goal, entrants were challenged to develop new intermolecular potential models for ethylene oxide (EO) and to us they predict a variety of physical properties. The predictions were judged by comparison to a set of benchmark values established based on peer-reviewed scientific literature and highly regarded property databases, and the results were generally excellent. A secondary objective was to assess the variability of those property predictions when performed by different researchers using the same force field (a "round-robin" experiment). To address this goal, entrants were challenged to calculate the same set of properties for a specific EO potential model from the literature, and good consistency was found between the predictions of most of the entrants. (c) 2008 Elsevier B.V. All rights reserved.
C1 [Chaka, Anne; Mountain, Raymond D.; Shen, Vincent K.] Natl Inst Stand & Technol, Gaithersburg, MD 20899 USA.
[Case, Fiona H.] Case Sci, Essex Jct, VT USA.
[Brennan, John] USA, Res Lab, Aberdeen Proving Ground, MD USA.
DuPont Co Inc, Wilmington, DE USA.
[Friend, Daniel G.] NIST, Boulder, CO USA.
[Gordon, Peter A.] ExxonMobil, Annandale, NJ USA.
[Moore, Jonathan D.] Dow Chem Co USA, Midland, MI 48674 USA.
[Olson, James D.] Dow Chem Co USA, S Charleston, WV USA.
[Ross, Richard B.] 3M Co, St Paul, MN 55144 USA.
[Stahlberg, Eric A.] Ohio Supercomp Ctr, Columbus, OH USA.
RP Mountain, RD (reprint author), Natl Inst Stand & Technol, 100 Bur Dr Stop 8380, Gaithersburg, MD 20899 USA.
EM Raymond.Mountain@nist.gov
RI Moore, Jonathan/B-8201-2009
NR 37
TC 26
Z9 26
U1 0
U2 7
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0378-3812
J9 FLUID PHASE EQUILIBR
JI Fluid Phase Equilib.
PD DEC 25
PY 2008
VL 274
IS 1-2
BP 2
EP 9
DI 10.1016/j.fluid.2008.05.009
PG 8
WC Thermodynamics; Chemistry, Physical; Engineering, Chemical
SC Thermodynamics; Chemistry; Engineering
GA 381WG
UT WOS:000261566000002
ER
PT J
AU Mulligan, CP
Blanchet, TA
Gall, D
AF Mulligan, C. P.
Blanchet, T. A.
Gall, D.
TI CrN-Ag nanocomposite coatings: Effect of growth temperature on the
microstructure
SO SURFACE & COATINGS TECHNOLOGY
LA English
DT Article; Proceedings Paper
CT 35th International Conference on Metallurgical Coatings and Thin Films
CY APR 28-MAY 02, 2008
CL San Diego, CA
SP Amer Vacuum Soc, Adv Surf Engn Div
DE Nanocomposite coating; Lubrication; Solid lubricant; High-temperature
lubrication; CrN-Ag
ID YTTRIA-STABILIZED ZIRCONIA; SURFACE MORPHOLOGICAL EVOLUTION;
TRIBOLOGICAL PROPERTIES; FILMS; DEPOSITION; FRICTION; MGO(001);
BEHAVIOR; CRALN; GOLD
AB CrN-Ag composite layers, 5-mu m-thick and containing 22 at.% Ag, were co-deposited by reactive magnetron sputtering on Si(001) substrates in a 0.4 Pa pure nitrogen atmosphere at growth temperatures T(s)=500, 600, and 700 degrees C. A combination of X-ray diffraction and cross-sectional microscopy analyses show that Ag segregates to form precipitates with an average size that increases from < 25 nm to similar to 300x300x 100 nm(3) to similar to 600x600x200 nm(3) for T(s) = 500, 600, and 700 degrees C respectively. At high T(s) the precipitates extend along the surface plane to form horizontal lamellae that cause grain re-nucleation and, in turn, a disruption of the columnar microstructure and a transition from a strong 002 texture for pure CrN to a mixed preferred orientation for the composite coatings. In addition, Ag segregates to form mounds on the growing layer surface that result in the nucleation of nodules which exhibit an increased growth rate and extend up to I and 5 mu m above the surface for T(s)=600 and 700 degrees C, respectively, but are absent for T(s)=500 degrees C. The cross-sectional microhardness increases with T(s) from 17 to 20 to 24 GPa for T(s)=500, 600, and 700 degrees C, respectively, which is attributed to a decrease in the effective Ag concentration associated with temperature-activated segregation. The measured hardness for pure CrN is 28 GPa. (c) 2008 Elsevier B.V. All rights reserved.
C1 [Mulligan, C. P.; Gall, D.] Rensselaer Polytech Inst, Dept Mat Sci & Engn, Troy, NY 12180 USA.
[Blanchet, T. A.] Rensselaer Polytech Inst, Dept Mech Aerosp & Nucl Engn, Troy, NY 12180 USA.
[Mulligan, C. P.] USA, Armament Res & Dev Ctr, Benet Labs, Watervliet, NY 12189 USA.
RP Gall, D (reprint author), Rensselaer Polytech Inst, Dept Mat Sci & Engn, Troy, NY 12180 USA.
EM galld@rpi.edu
RI Gall, Daniel/B-1060-2008
OI Gall, Daniel/0000-0002-5762-9307
NR 23
TC 32
Z9 35
U1 3
U2 13
PU ELSEVIER SCIENCE SA
PI LAUSANNE
PA PO BOX 564, 1001 LAUSANNE, SWITZERLAND
SN 0257-8972
J9 SURF COAT TECH
JI Surf. Coat. Technol.
PD DEC 25
PY 2008
VL 203
IS 5-7
BP 584
EP 587
DI 10.1016/j.surfcoat.2008.06.052
PG 4
WC Materials Science, Coatings & Films; Physics, Applied
SC Materials Science; Physics
GA 383DK
UT WOS:000261654100038
ER
PT J
AU Pappas, DD
Bujanda, AA
Orlicki, JA
Jensen, RE
AF Pappas, D. Daphne
Bujanda, Andres A.
Orlicki, Joshua A.
Jensen, Robert E.
TI Chemical and morphological modification of polymers under a
helium-oxygen dielectric barrier discharge
SO SURFACE & COATINGS TECHNOLOGY
LA English
DT Article; Proceedings Paper
CT 35th International Conference on Metallurgical Coatings and Thin Films
CY APR 28-MAY 02, 2008
CL San Diego, CA
SP Amer Vacuum Soc, Adv Surf Engn Div
DE Dialectric barrier discharge; Polymers; XPS; SEM; Wettability
ID SURFACE OXIDATION
AB In this work, the surface modifications of various polymer films due to helium-oxygen dielectric barrier discharge (DBD) exposure operating under atmospheric pressure are reported. The polymer films studied include ultra high molecular weight polyethylene, polyamide, polytetrafluoroethylene and polyimide. Experimental results reveal increased hydrophilicity and surface energy of the plasma exposed polymers. This is attributed to the presence of oxygen containing groups grafted onto the surface during plasma treatment, as confirmed by X-ray photoelectron spectroscopy (XPS) analysis. Scanning electron microscopy (SEM) data show the appearance of micro depressions, the size of which depends on the chemical structure and the treatment time, suggesting that mild etching occurs in a predicted fashion. Most importantly, this uniform modification occurs within a few seconds of exposure, time comparable to continuous on-line industrial processing. Published by Elsevier B.V.
C1 [Pappas, D. Daphne; Bujanda, Andres A.; Orlicki, Joshua A.; Jensen, Robert E.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Pappas, DD (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
EM daphne.pappas@us.army.mil
OI Pappas, Daphne/0000-0002-5746-8873
NR 15
TC 24
Z9 25
U1 1
U2 5
PU ELSEVIER SCIENCE SA
PI LAUSANNE
PA PO BOX 564, 1001 LAUSANNE, SWITZERLAND
SN 0257-8972
J9 SURF COAT TECH
JI Surf. Coat. Technol.
PD DEC 25
PY 2008
VL 203
IS 5-7
BP 830
EP 834
DI 10.1016/j.surfcoat.2008.05.029
PG 5
WC Materials Science, Coatings & Films; Physics, Applied
SC Materials Science; Physics
GA 383DK
UT WOS:000261654100090
ER
PT J
AU Illick, MM
Branco, LM
Fair, JN
Illick, KA
Matschiner, A
Schoepp, R
Garry, RF
Guttieri, MC
AF Illick, Megan M.
Branco, Luis M.
Fair, Joseph N.
Illick, Kerry A.
Matschiner, Alex
Schoepp, Randal
Garry, Robert F.
Guttieri, Mary C.
TI Uncoupling GP1 and GP2 expression in the Lassa virus glycoprotein
complex: implications for GP1 ectodomain shedding
SO VIROLOGY JOURNAL
LA English
DT Article
ID LYMPHOCYTIC CHORIOMENINGITIS VIRUS; STABLE SIGNAL PEPTIDE; EBOLA-VIRUS;
MONOCLONAL-ANTIBODIES; FEVER; IDENTIFICATION; INFECTION; PROTEINS;
VECTORS; SYSTEMS
AB Background: Sera from convalescent Lassa fever patients often contains antibodies to Lassa virus (LASV) glycoprotein 1 (GP1), and glycoprotein 2 (GP2); Immunization of non-human primates with viral vectors expressing the arenaviral glycoprotein complex (GPC) confers full protective immunity against a lethal challenge with LASV. Thus, the development of native or quasi native recombinant LASV GP1 and GP2 as soluble, uncoupled proteins will improve current diagnostics, treatment, and prevention of Lassa fever. To this end, mammalian expression systems were engineered for production and purification of secreted forms of soluble LASV GP1 and GP2 proteins.
Results: Determinants for mammalian cell expression of secreted uncoupled Lassa virus (LASV) glycoprotein 1 (GP1) and glycoprotein 2 (GP2) were established. Soluble GP1 was generated using either the native glycoprotein precursor (GPC) signal peptide (SP) or human IgG signal sequences (s.s.). GP2 was secreted from cells only when (1) the transmembrane (TM) domain was deleted, the intracellular domain (IC) was fused to the ectodomain, and the gene was co-expressed with a complete GP1 gene in cis; (2) the TM and IC domains were deleted and GP1 was co-expressed in cis; (3) expression of GP1 was driven by the native GPC SP. These data implicate GP1 as a chaperone for processing and shuttling GP2 to the cell surface. The soluble forms of GP1 and GP2 generated through these studies were secreted as homogeneously glycosylated proteins that contained high mannose glycans. Furthermore, observation of GP1 ectodomain shedding from cells expressing wild type LASV GPC represents a novel aspect of arenaviral glycoprotein expression.
Conclusion: These results implicate GP1 as a chaperone for the correct processing and shuttling of GP2 to the cell surface, and suggest that native GPC SP plays a role in this process. In the absence of GP1 and GPC SP the GP2 protein may be processed by an alternate pathway that produces heterogeneously glycosylated protein, or the polypeptide may not fully mature in the secretory cascade in mammalian cells. The expression constructs developed in these studies resulted in the generation and purification of soluble, uncoupled GP1 and GP2 proteins from mammalian cells with quasinative properties. The observation of GP1 ectodomain shedding from cells expressing wild type LASV GPC establishes new correlates of disease progression and highlights potential opportunities for development of diagnostics targeting the early stages of Lassa fever.
C1 [Branco, Luis M.; Fair, Joseph N.; Garry, Robert F.] Tulane Univ, Hlth Sci Ctr, New Orleans, LA 70118 USA.
[Illick, Megan M.; Illick, Kerry A.; Matschiner, Alex] BioFactura Inc, Rockville, MD USA.
[Fair, Joseph N.] Tulane Univ, Sch Publ Hlth & Trop Med, New Orleans, LA 70118 USA.
[Fair, Joseph N.; Guttieri, Mary C.] USA, Med Res Inst Infect Dis, Div Virol, Ft Detrick, MD 21702 USA.
[Illick, Kerry A.] Cedar Crest Muhlenberg Coll, Dept Sci, Allentown, PA 18104 USA.
[Schoepp, Randal] USA, Med Res Inst Infect Dis, Diagnost Syst Div, Ft Detrick, MD 21702 USA.
RP Garry, RF (reprint author), Tulane Univ, Hlth Sci Ctr, New Orleans, LA 70118 USA.
EM millick@biofactura.com; lbranco@tulane.edu; fair@southernresearch.org;
kaillick@cedarcrest.edu; amatschiner@biofactura.com;
randal.schoepp@amedd.army.mil; rfgarry@tulane.edu; marycguttieri@aol.com
RI Valle, Ruben/A-7512-2013
FU NIAID NIH HHS [1 UC1 AI067188-01, UC1 AI067188]
NR 31
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Z9 10
U1 0
U2 4
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1743-422X
J9 VIROL J
JI Virol. J.
PD DEC 23
PY 2008
VL 5
AR 161
DI 10.1186/1743-422X-5-161
PG 17
WC Virology
SC Virology
GA 414CA
UT WOS:000263840300001
PM 19105844
ER
PT J
AU Lim, W
Douglas, EA
Kim, SH
Norton, DP
Pearton, SJ
Ren, F
Shen, H
Chang, WH
AF Lim, Wantae
Douglas, E. A.
Kim, S.-H.
Norton, D. P.
Pearton, S. J.
Ren, F.
Shen, H.
Chang, W. H.
TI Low-temperature-fabricated InGaZnO4 thin film transistors on polyimide
clean-room tape
SO APPLIED PHYSICS LETTERS
LA English
DT Article
DE carrier density; carrier mobility; flexible electronics; gallium
compounds; indium compounds; polymers; semiconductor growth;
semiconductor thin films; sputter deposition; substrates; ternary
semiconductors; thin film transistors; zinc compounds
ID AMORPHOUS OXIDE SEMICONDUCTORS
AB Amorphous (alpha-)InGaZnO4 thin film transistors (TFTs) were fabricated on polyimide clean-room tape at low temperature (< 100 degrees C). The alpha-InGaZnO4 films with an n-type carrier concentration of similar to 10(16) cm(-3) were deposited by rf-magnetron sputtering in a mixed ambient of Ar/O-2. The bottom-gate-type TFTs showed good saturation mobility (similar to 5.3 cm(2) V-1 s(-1)), drain current on-to-off ratio of approximately 10(5), threshold voltage of 1.1 V, and subthreshold gate-voltage swing of 0.55 V decade(-1). These results were comparable to those of the same oxide TFTs that we have fabricated on either glass or polyethylene terephthalate substrates. The results demonstrate that even polyimide clean-room tape can be an appropriate substrate for inexpensive-flexible-adhesive-transparent electronic devices.
C1 [Lim, Wantae; Douglas, E. A.; Kim, S.-H.; Norton, D. P.; Pearton, S. J.] Univ Florida, Dept Mat Sci & Engn, Gainesville, FL 32611 USA.
[Ren, F.] Univ Florida, Dept Chem Engn, Gainesville, FL 32611 USA.
[Shen, H.; Chang, W. H.] Army Res Lab, Sensors & Electron Devices Directorate, Adelphi, MD 20783 USA.
RP Lim, W (reprint author), Univ Florida, Dept Mat Sci & Engn, Gainesville, FL 32611 USA.
EM spear@mse.ufl.edu
RI Douglas, Erica/J-3732-2014
OI Douglas, Erica/0000-0003-1873-0223
NR 23
TC 34
Z9 35
U1 2
U2 13
PU AMER INST PHYSICS
PI MELVILLE
PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1,
MELVILLE, NY 11747-4501 USA
SN 0003-6951
J9 APPL PHYS LETT
JI Appl. Phys. Lett.
PD DEC 22
PY 2008
VL 93
IS 25
AR 252103
DI 10.1063/1.3054167
PG 3
WC Physics, Applied
SC Physics
GA 388GQ
UT WOS:000262008700023
ER
PT J
AU Cohen, SP
Argoff, CE
Carragee, EJ
AF Cohen, Steven P.
Argoff, Charles E.
Carragee, Eugene J.
TI Management of low back pain
SO BRITISH MEDICAL JOURNAL
LA English
DT Review
ID CLINICAL-PRACTICE GUIDELINE; PRIMARY-CARE; FACET JOINT; DIAGNOSIS;
PHYSICIANS; IDENTIFY; THERAPY; COLLEGE; NECK
C1 [Cohen, Steven P.] Johns Hopkins Univ, Sch Med, Dept Anesthesiol & Crit Care Med, Pain Management Div, Baltimore, MD 21205 USA.
[Cohen, Steven P.] Walter Reed Army Med Ctr, Dept Surg, Washington, DC 20307 USA.
[Argoff, Charles E.] Albany Med Coll, Dept Neurol, Comprehens Pain Program, Albany, NY 12208 USA.
[Carragee, Eugene J.] Stanford Univ, Sch Med, Dept Orthoped Surg, Div Spine Surg, Stanford, CA 94305 USA.
RP Cohen, SP (reprint author), 550 N Broadway,Suite 301, Baltimore, MD 21205 USA.
EM scohen40@jhmi.edu
NR 23
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U1 1
U2 7
PU B M J PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 0959-8146
J9 BRIT MED J
JI Br. Med. J.
PD DEC 22
PY 2008
VL 337
AR a2718
DI 10.1136/bmj.a2718
PG 14
WC Medicine, General & Internal
SC General & Internal Medicine
GA 394EI
UT WOS:000262428100001
PM 19103627
ER
PT J
AU Folkes, PA
AF Folkes, Patrick A.
TI Interband cascade laser photon noise
SO JOURNAL OF PHYSICS D-APPLIED PHYSICS
LA English
DT Article
ID INTENSITY FLUCTUATIONS; SEMICONDUCTOR-LASERS; QUANTUM-WELLS; MODEL
AB We report measurements of the low-frequency photon noise and the relative intensity noise of an interband cascade laser as a function of laser current at 30 and 100 K. Away from threshold, the laser primarily exhibits a frequency-independent photon noise spectral density in agreement with theory. At threshold, the observed photon noise spectral density exhibits large fluctuations at closely spaced discrete frequencies. Thermal effects at 100 K result in a large increase in the photon noise above threshold.
C1 USA, Res Lab, Adelphi, MD 20783 USA.
RP Folkes, PA (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
NR 27
TC 2
Z9 2
U1 0
U2 0
PU IOP PUBLISHING LTD
PI BRISTOL
PA DIRAC HOUSE, TEMPLE BACK, BRISTOL BS1 6BE, ENGLAND
SN 0022-3727
J9 J PHYS D APPL PHYS
JI J. Phys. D-Appl. Phys.
PD DEC 21
PY 2008
VL 41
IS 24
AR 245109
DI 10.1088/0022-3727/41/24/245109
PG 4
WC Physics, Applied
SC Physics
GA 379GC
UT WOS:000261383700016
ER
PT J
AU Grujicic, M
Arakere, G
He, T
Bell, WC
Cheeseman, BA
Yen, CF
Scott, B
AF Grujicic, M.
Arakere, G.
He, T.
Bell, W. C.
Cheeseman, B. A.
Yen, C. -F.
Scott, B.
TI A ballistic material model for cross-plied unidirectional ultra-high
molecular-weight polyethylene fiber-reinforced armor-grade composites
SO MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES
MICROSTRUCTURE AND PROCESSING
LA English
DT Article
DE Flexible armor; Armor-grade composites; Material model; High-performance
fibers; Ballistic performance
ID LAMINATED KEVLAR; IMPACT; PENETRATION; PROJECTILES; MECHANISMS; FAILURE;
EPOXY
AB The known fiber and polymeric-matrix material properties, unit-cell microstructural characteristics and unit-cell level finite-element analyses are used to construct a new ballistic material model for 0 degrees/90 degrees crossplied oriented polyethylene fiber-based armor-grade composite laminates. The model is constructed in such a way that it can be readily integrated into commercial finite-element programs like ANSYS/Autodyn [ANSYS/Autodyn version 11.0, User Documentation, Century Dynamics Inc., a subsidiary of ANSYS Inc., 20071 and ABAQUS/Explicit [ABAQUS version 6.7, User Documentation, Dessault Systems, 2007] as a user material subroutine. To validate the model, a series of transient non-linear dynamics simulations of the transverse impact of armor-grade composite laminates with two types of bullets/projectiles is carried out. The results obtained are next compared with their experimental counterparts. This comparison revealed that a relatively good agreement is obtained between the experimental and the computational analysis relative to: (a) the success of the armor panels of different areal densities in defeating the bullets at different initial bullet velocities; (b) post-mortem spatial distribution of damage within the panels; (c) the temporal evolution of a bulge at the back-face of the armor; and (d) the existence of three distinct armor-penetration stages (i.e. an initial filament shearing/cutting dominated stage, an intermediate stage characterized by pronounced filament/matrix de-bonding/decohesion and the final stage associated with the extensive bulging of the armor panel). (C) 2008 Elsevier B.V. All rights reserved.
C1 [Grujicic, M.; Arakere, G.; He, T.; Bell, W. C.] Clemson Univ, Dept Mech Engn, Int Ctr Automot Res CU ICAR, Clemson, SC 29634 USA.
[Cheeseman, B. A.; Yen, C. -F.; Scott, B.] USA, Res Lab, Survivabil Mat Branch, Aberdeen Proving Ground, MD 21005 USA.
RP Grujicic, M (reprint author), Clemson Univ, Dept Mech Engn, Int Ctr Automot Res CU ICAR, 241 Engn Innovat Bldg, Clemson, SC 29634 USA.
EM mica.grujicic@ces.clemson.edu
FU U.S. Army/Clemson University [W911 NF-04-2-0024, W911 NF-06-2-0042]
FX The material presented in this paper is based on work supported by the
U.S. Army/Clemson University Cooperative Agreements W911 NF-04-2-0024
and W911 NF-06-2-0042.
NR 36
TC 45
Z9 47
U1 2
U2 23
PU ELSEVIER SCIENCE SA
PI LAUSANNE
PA PO BOX 564, 1001 LAUSANNE, SWITZERLAND
SN 0921-5093
J9 MAT SCI ENG A-STRUCT
JI Mater. Sci. Eng. A-Struct. Mater. Prop. Microstruct. Process.
PD DEC 20
PY 2008
VL 498
IS 1-2
SI SI
BP 231
EP 241
DI 10.1016/j.msea.2008.07.056
PG 11
WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary;
Metallurgy & Metallurgical Engineering
SC Science & Technology - Other Topics; Materials Science; Metallurgy &
Metallurgical Engineering
GA 379UA
UT WOS:000261420500033
ER
PT J
AU Taylor, WRJ
Widjaja, H
Basri, H
Ohrt, C
Taufik, T
Tjitra, E
Baso, S
Fryauff, D
Hoffman, SL
Richie, TL
AF Taylor, Walter R. J.
Widjaja, Hendra
Basri, Hasan
Ohrt, Colin
Taufik, Taufik
Tjitra, Emiliana
Baso, Samuel
Fryauff, David
Hoffman, Stephen L.
Richie, Thomas L.
TI Changes in the total leukocyte and platelet counts in Papuan and non
Papuan adults from northeast Papua infected with acute Plasmodium vivax
or uncomplicated Plasmodium falciparum malaria
SO MALARIA JOURNAL
LA English
DT Article
ID CLINICAL-FEATURES; PERIPHERAL-BLOOD; GAMBIAN CHILDREN; IMPORTED MALARIA;
IRIAN-JAYA; THROMBOCYTOPENIA; COMBINATION; MECHANISMS; INDONESIA;
SOLDIERS
AB Background: There are limited data on the evolution of the leukocyte and platelet counts in malaria patients.
Methods: In a clinical trial of chloroquine vs. chloroquine plus doxycycline vs. doxycycline alone against Plasmodium vivax (n = 64) or Plasmodium falciparum (n = 98) malaria, the total white cell (WCC) and platelet (PLT) counts were measured on Days 0, 3, 7 and 28 in 57 indigenous Papuans with life long malaria exposure and 105 non Papuan immigrants from other parts of Indonesia with limited malaria exposure.
Results: The mean Day 0 WCC (n = 152) was 6.492 (range 2.1-13.4) x 10(9)/L and was significantly lower in the Papuans compared to the non Papuans: 5.77 x 10(9)/L vs. 6.86 x 10(9)/L, difference = -1.09 [(95% CI -0.42 to -1.79 x 10(9)/L), P = 0.0018]. 14 (9.2%) and 9 (5.9%) patients had leukopaenia (<4.0 x 10(9)/L) and leukocytosis (>10.0 x 10(9)/L), respectively. By Day 28, the mean WCC increased significantly (P = 0.0003) from 6.37 to 7.47 x 10(9)/L (73 paired values) and was similar between the two groups. Ethnicity was the only WCC explanatory factor and only on Day 0.
The mean Day 0 platelet count (n = 151) was 113.0 (range 8.0-313.0) x 10(9)/L and rose significantly to 186.308 x 10(9)/L by Day 28 (P < 0.0001). There was a corresponding fall in patient proportions with thrombocytopaenia (< 150 x 10(9)/L): 119/151 (78.81%) vs. 16/73 (21.92%, P < 0.00001). Papuan and non Papuan mean platelet counts were similar at all time points. Only malaria species on Day 0 was a significant platelet count explanatory factor. The mean D0 platelet counts were significantly lower (P = 0.025) in vivax (102.022 x 10(9)/L) vs. falciparum (122.125 x 10(9)/L) patients.
Conclusion: Changes in leukocytes and platelets were consistent with other malaria studies. The Papuan non Papuan difference in the mean Day 0 WCC was small but might be related to the difference in malaria exposure.
C1 [Taylor, Walter R. J.; Widjaja, Hendra; Basri, Hasan; Fryauff, David; Richie, Thomas L.] US Navy Med Res Unit 2, Jakarta, Indonesia.
[Taylor, Walter R. J.] Tulane Univ, Sch Publ Hlth, Dept Trop Med, New Orleans, LA 70118 USA.
[Ohrt, Colin] Walter Reed Army Med Ctr, Walter Reed Army Inst Res, Div Expt Therapeut, Washington, DC 20307 USA.
[Taufik, Taufik] Indonesian Naval Hosp, Jayapura, Papua, Indonesia.
[Tjitra, Emiliana] Natl Inst Hlth, Ctr Hlth Res & Dev, Jakarta, Indonesia.
[Baso, Samuel] Rumah Sakit Umum, Jayapura, Papua, Indonesia.
[Hoffman, Stephen L.] USN, Med Res Ctr, Bethesda, MD USA.
RP Taylor, WRJ (reprint author), US Navy Med Res Unit 2, Jakarta, Indonesia.
EM btaylor@oucru.org; Hwidjaja@fhi.or.id; Hbasri@fhi.or.id;
Cohrt@wrair.mil.gov; Taufik@yahoo.com; emilt@litbang.depkes.go.id;
Sbaso@yahoo.com; FryauffD@NMRC.NAVY.MIL; slhoffman@sanaria.com;
RichieT@NMRC.NAVY.MIL
OI Richie, Thomas/0000-0002-2946-5456
FU US Naval Medical Research and Development Command [DoD 63002A M00101 HEX
2406]
FX This study was funded by the US Naval Medical Research and Development
Command (DoD 63002A M00101 HEX 2406)
NR 45
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U1 0
U2 0
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1475-2875
J9 MALARIA J
JI Malar. J.
PD DEC 18
PY 2008
VL 7
AR 259
DI 10.1186/1475-2875-7-259
PG 8
WC Infectious Diseases; Parasitology; Tropical Medicine
SC Infectious Diseases; Parasitology; Tropical Medicine
GA 409ZI
UT WOS:000263543900001
PM 19094197
ER
PT J
AU Ramkumar, SS
Love, AH
Sata, UR
Koester, CJ
Smith, WJ
Keating, GA
Hobbs, LW
Cox, SB
Lagna, WM
Kendall, RJ
AF Ramkumar, Seshadri S.
Love, Adam H.
Sata, Utkarsh R.
Koester, Carolyn J.
Smith, William J.
Keating, Garrett A.
Hobbs, Lawrence W.
Cox, Stephen B.
Lagna, William M.
Kendall, Ronald J.
TI Next-Generation Nonparticulate Dry Nonwoven Pad for Chemical Warfare
Agent Decontamination
SO INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
LA English
DT Article
ID CARBON FABRICS
AB New, nonparticulate decontamination materials promise to reduce both military and civilian casualties by enabling individuals to decontaminate themselves and their equipment within minutes of exposure to chemical warfare agents or other toxic materials. One of the most promising decontaminating materials has been developed using a needle-punching nonwoven process to construct a nonparticulate composite fabric of multiple layers, including an inner layer of activated carbon fabric, which is well-suited for the decontamination of both personnel and equipment. This paper describes the development of a composite nonwoven pad and compares efficacy test results for this pad with results from testing other decontamination systems. The efficacy of the dry nonwoven fabric pad was demonstrated specifically for decontamination of the chemical warfare blister agent bis(2-chloroethyl)sulfide (HD or sulfur mustard). Gas chromatography/mass spectroscopy (GC/MS) results indicate that the composite fabric was capable of significantly reducing the vapor hazard from mustard liquid absorbed into the nonwoven dry fabric pad. The mustard adsorption efficiency of the nonwoven pad was significantly higher than that of particulate activated carbon and was similar to the currently fielded U.S. military M291 kit. The nonwoven pad has several advantages over other materials, especially its nonparticulate, yet flexible, construction. This composite fabric was also shown to be chemically compatible with potential toxic and hazardous liquids, which span a range of hydrophilic and hydrophobic chemicals, including a concentrated acid, an organic solvent, and a mild oxidant (bleach).
C1 [Ramkumar, Seshadri S.; Sata, Utkarsh R.; Cox, Stephen B.; Kendall, Ronald J.] Texas Tech Univ, Inst Environm & Human Hlth, Lubbock, TX 79409 USA.
[Love, Adam H.; Koester, Carolyn J.; Smith, William J.; Keating, Garrett A.] Lawrence Livermore Natl Lab, Forens Sci Ctr, Livermore, CA 94550 USA.
[Hobbs, Lawrence W.] Hobbs Bonded Fibers, Waco, TX 76710 USA.
[Lagna, William M.] USA, Edgewood Chem Biol Ctr, Res Dev & Engn Command, AMSRD ECB RT D, Aberdeen Proving Ground, MD 21010 USA.
RP Ramkumar, SS (reprint author), Texas Tech Univ, Inst Environm & Human Hlth, Lubbock, TX 79409 USA.
EM s.ramkumar@ttu.edu
RI Cox, Stephen/A-5037-2010
FU U.S. Department of Energy by University of California; Lawrence
Livermore National Laboratory [W-7405-Eng-48]; Food and Fibers Research
Grant Program of Texas
FX The evaluation of this composite wipe was part of a DHS-funded project,
managed by the Technical Support Working Group (TSWG), to develop a
Low-Cost Personal Decontamination System. The project was performed
under the auspices of the U.S. Department of Energy by University of
California, Lawrence Livermore National Laboratory (under Contract
W-7405-Eng-48). S.R. gratefully acknowledges the U.S. Army Research, the
Development and Engineering Command of the U.S. Department of Defense,
for broad-based support of his research on nonwoven fabrics for personal
protection and decontamination. S.R. also acknowledges the Food and
Fibers Research Grant Program of Texas, The CH Foundation of Lubbock,
Cotton Foundation, South Plains Foundation, Lubbock, ICRC of CASNR-TTU
and Plains Cotton Growers, Inc. for supporting his nonwovens research at
Texas Tech University. Garfield Purdon and Andrew Burczyk of Defence
Research and Development Canada-Suffield, Philip O'Dell of O'Dell
Engineering, and Nayla Feghali of E-Z-EM, Inc., provided valuable
insights into the design and performance requirements for the dry pad.
NR 23
TC 7
Z9 7
U1 1
U2 12
PU AMER CHEMICAL SOC
PI WASHINGTON
PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
SN 0888-5885
J9 IND ENG CHEM RES
JI Ind. Eng. Chem. Res.
PD DEC 17
PY 2008
VL 47
IS 24
BP 9889
EP 9895
DI 10.1021/ie801223b
PG 7
WC Engineering, Chemical
SC Engineering
GA 382TU
UT WOS:000261629100011
ER
PT J
AU He, H
Pandey, R
Karna, SP
AF He, Haiying
Pandey, Ravindra
Karna, Shashi P.
TI Electronic conduction in a model three-terminal molecular transistor
SO NANOTECHNOLOGY
LA English
DT Article
ID NEGATIVE DIFFERENTIAL RESISTANCE; CARBON NANOTUBE; SINGLE; TRANSPORT;
DENSITY; WIRES
AB The electronic conduction of a novel, three-terminal molecular architecture, analogous to a heterojunction bipolar transistor, is studied. In this architecture, two diode arms consisting of donor-acceptor molecular wires fuse through a ring, while a gate modulating wire is a pi-conjugated wire. The calculated results show the enhancement or depletion mode of a transistor on applying a gate field along the positive or negative direction. A small gate field is required to switch on the current in the proposed architecture. The changes in the electronic conduction can be attributed to the intrinsic dipolar molecular architecture in terms of the evolution of molecular wavefunctions, specifically the one associated with the terphenyl group of the modulating wire in the presence of the gate field.
C1 [He, Haiying; Pandey, Ravindra] Michigan Technol Univ, Dept Phys, Houghton, MI 49931 USA.
[He, Haiying; Pandey, Ravindra] Michigan Technol Univ, Multi Scale Technol Inst, Houghton, MI 49931 USA.
[Karna, Shashi P.] USA, Res Lab, Weapons & Mat Res Directorate, ATTN AMSRD ARL WM, Aberdeen Proving Ground, MD 21005 USA.
RP Pandey, R (reprint author), Michigan Technol Univ, Dept Phys, Houghton, MI 49931 USA.
EM pandey@mtu.edu; skarna@arl.army.mil
OI He, Haiying/0000-0002-3493-2784
FU DARPA [ARL-DAAD17-03-C-0115]; ARL-Director's Research [FY05-WMR01]
FX The work at Michigan Technological University was performed under
support by the DARPA through contract number ARL-DAAD17-03-C-0115. The
work at Army Research Laboratory (ARL) was supported by the DARPA
MoleApps program and ARL-Director's Research Initiative-FY05-WMR01.
Helpful discussions with G Mallick, S Gowtham, K C Lau and R Pati are
gratefully acknowledged.
NR 31
TC 10
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U1 0
U2 3
PU IOP PUBLISHING LTD
PI BRISTOL
PA DIRAC HOUSE, TEMPLE BACK, BRISTOL BS1 6BE, ENGLAND
SN 0957-4484
J9 NANOTECHNOLOGY
JI Nanotechnology
PD DEC 17
PY 2008
VL 19
IS 50
AR 505203
DI 10.1088/0957-4484/19/50/505203
PG 6
WC Nanoscience & Nanotechnology; Materials Science, Multidisciplinary;
Physics, Applied
SC Science & Technology - Other Topics; Materials Science; Physics
GA 376TK
UT WOS:000261205700007
PM 19942764
ER
PT J
AU Anderson, GP
Liu, JL
Hale, ML
Bernstein, RD
Moore, M
Swain, MD
Goldman, ER
AF Anderson, George P.
Liu, Jinny L.
Hale, Martha L.
Bernstein, Rachael D.
Moore, Martin
Swain, Maria D.
Goldman, Ellen R.
TI Development of Antiricin Single Domain Antibodies Toward Detection and
Therapeutic Reagents
SO ANALYTICAL CHEMISTRY
LA English
DT Article
ID RICIN; FRAGMENTS; BIOSENSOR; IDENTIFICATION; EXPRESSION; STABILITY;
SELECTION; PROTEINS; SEQUENCE; ANTIGEN
AB Single domain antibodies (sdAb) that bind ricin with high affinity and specificity were selected from a phage display library derived from the mRNA of heavy chain antibodies obtained from lymphocytes of immunized llamas. The sdAb were found to recognize three distinct epitopes on ricin. Representative sdAb were demonstrated to function as both capture and tracer elements in fluid array immunoassays, a limit of detection of 1.6 ng/mL was obtained. One sdAb pair in particular was found to be highly specific for ricin. While polyclonal antibodies cross react strongly with RCA120, the sdAb pair had minimal cross reactivity. In addition, the binders were found to be thermal stable, regaining their ricin binding activity following heating to 85 T for an hour. Cycles of thermally induced unfolding of the sdAb and their subsequent refolding upon cooling was monitored by circular dichroism. As several of the sdAb were observed to bind to ricin's A chain, cell free translation assays were performed to monitor the ability of the sdAbs to inhibit ricin's biological activity. One of the sdAb (C8) was particularly effective and blocked ricin's biological activity with an effectiveness equal to that of a mouse antiricin antibody. These results indicate that antiricin sdAb have great potential for both diagnostic and therapeutic applications.
C1 [Anderson, George P.; Liu, Jinny L.; Moore, Martin; Swain, Maria D.; Goldman, Ellen R.] USN, Res Lab, Ctr Biomol Sci & Engn, Washington, DC 20375 USA.
[Hale, Martha L.] USA, Med Res Inst Infect Dis, Integrated Toxicol Div, Frederick, MD 21702 USA.
[Bernstein, Rachael D.] Nova Res Inc, Alexandria, VA 22308 USA.
RP Goldman, ER (reprint author), USN, Res Lab, Ctr Biomol Sci & Engn, 4555 Overlook Ave SW, Washington, DC 20375 USA.
EM ellen.goldman@nrl.navy.mil
RI Anderson, George/D-2461-2011
OI Anderson, George/0000-0001-7545-9893
FU JSTO-CBD/DTRA; U.S. Navy, the U.S. Department of Defense, or the U.S.
government
FX This work was supported by JSTO-CBD/DTRA. The opinions expressed here
are those of the authors and do not represent those of the U.S. Navy,
the U.S. Department of Defense, or the U.S. government.
NR 33
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U1 0
U2 4
PU AMER CHEMICAL SOC
PI WASHINGTON
PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
SN 0003-2700
J9 ANAL CHEM
JI Anal. Chem.
PD DEC 15
PY 2008
VL 80
IS 24
BP 9604
EP 9611
DI 10.1021/ac8019398
PG 8
WC Chemistry, Analytical
SC Chemistry
GA 384FE
UT WOS:000261728900029
PM 19072267
ER
PT J
AU Chen, XJJ
West, AC
Cropek, DM
Banta, S
AF Chen, Xiaojun J.
West, Alan C.
Cropek, Donald M.
Banta, Scott
TI Detection of the Superoxide Radical Anion Using Various Alkanethiol
Monolayers and Immobilized Cytochrome c
SO ANALYTICAL CHEMISTRY
LA English
DT Article
ID SELF-ASSEMBLED MONOLAYER; 3RD-GENERATION BIOSENSOR; NITRIC-OXIDE;
DISMUTASE; ELECTRODES; REPERFUSION; ISCHEMIA; COPPER
AB The superoxide radical anion (SO) is a critical biomarker for monitoring cellular stress responses. Electrochemical SO biosensors are frequently constructed through the covalent immobilization of cytochrome c (Cyt c) onto self-assembled monolayers (SAMs); however, a detailed comparison of these systems as well as configuration influence on SO detection is needed to enable robust applications. Two reaction pathways, oxidation of SO by the SAM-modified gold electrode or electron transfer through a protein and monolayer relay, may be involved during the electrochemical detection of SO with Cyt c, depending on the SAM that is used. Although electrodes with SAMs alone can exhibit a high sensitivity and low limit of detection (LOD) for the SO, they can suffer from a strong response to the presence of interferents such as hydrogen peroxide and ascorbic acid. Electrodes with immobilized Cyt c show decreased sensitivity, but exhibit better selectivity and resistance to fouling in complex media. Considering the trade-offs between sensitivity, selectivity, and LOD for SO detection, a bioelectrode made with Cyt c immobilized on dithiobis(succinimidyl)propionate (DISP) appears to be the most suitable configuration. In phosphate buffer, the DTSP/Cyt c electrode has a sensitivity of 410 nA mu M(-1) cm(-1) and an LOD for SO of 73 nM. Results are also presented for the detection of SO in a complex tissue culture media (MEM) with and without serum, and the sensitivity of the DTSP/Cyt c in MEM in the absence of serum increased to 640 nA mu M(-1) cm(-1). By measuring SO with a DTSP/Cyt c electrode before and after the addition of a bolus of the superoxide dismutase (SOD) enzyme, the specificity of the SOD enzyme can be combined with the sensitivity of Cyt c system.
C1 [Chen, Xiaojun J.; West, Alan C.; Banta, Scott] Columbia Univ, Dept Chem Engn, New York, NY 10027 USA.
[Chen, Xiaojun J.; Cropek, Donald M.] USA, Engn Res & Dev Ctr, Construct Engn Res Lab, Champaign, IL 61826 USA.
RP Banta, S (reprint author), Columbia Univ, Dept Chem Engn, New York, NY 10027 USA.
EM sbanta@cheme.columbia.edu
FU U.S: Army Applied Research
FX This research was supported by the U.S: Army Applied Research Program.
We thank Lt. Col. Robert Bozic for helpful discussions and assistance.
NR 32
TC 37
Z9 37
U1 3
U2 38
PU AMER CHEMICAL SOC
PI WASHINGTON
PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
SN 0003-2700
J9 ANAL CHEM
JI Anal. Chem.
PD DEC 15
PY 2008
VL 80
IS 24
BP 9622
EP 9629
DI 10.1021/ac800796b
PG 8
WC Chemistry, Analytical
SC Chemistry
GA 384FE
UT WOS:000261728900031
PM 19072268
ER
PT J
AU Alhamadsheh, MM
Waters, NC
Sachdeva, S
Lee, P
Reynolds, KA
AF Alhamadsheh, Mamoun M.
Waters, Norman C.
Sachdeva, Sarbjot
Lee, Patricia
Reynolds, Kevin A.
TI Synthesis and biological evaluation of novel
sulfonyl-naphthalene-1,4-diols as FabH inhibitors
SO BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
LA English
DT Article
DE FabH; Fatty acid biosynthesis; SAR; Plasmodium falciparum; Inhibition
ID PROTEIN SYNTHASE-III; FATTY-ACID BIOSYNTHESIS;
MYCOBACTERIUM-TUBERCULOSIS; CRYSTAL-STRUCTURE; DISCOVERY
AB A series of analogs of 2-tosylnaphthalene-1,4-diol were prepared and were found to be potent 10-20 nM reversible inhibitors of the Escherichia coli FabH enzyme. The inhibitors were also effective but to a lesser degree (30 nM-5 mu M), against the Mycobacterium tuberculosis and Plasmodium falciparum FabH enzymes. Preliminary SAR studies demonstrated that the sulfonyl group and naphthalene-1,4 diol were required for activity against all enzymes but the toluene portion could be significantly altered and leads to either modest increases or decreases in activity against the three enzymes. The in vitro activity of the analogs against E. coli FabH parallel the in vivo activity against E. coli TolC strain and many of the compounds were also shown to have antimalarial activity against P. falciparum. (C) 2008 Published by Elsevier Ltd.
C1 [Alhamadsheh, Mamoun M.; Sachdeva, Sarbjot; Reynolds, Kevin A.] Portland State Univ, Dept Chem, Portland, OR 97207 USA.
[Waters, Norman C.; Lee, Patricia] Walter Reed Army Inst Res, Div Expt Therapeut, Silver Spring, MD 20910 USA.
RP Reynolds, KA (reprint author), Portland State Univ, Dept Chem, Portland, OR 97207 USA.
EM reynoldsk@pdx.edu
OI Reynolds, Kevin/0000-0003-0270-9809
FU National Institutes of Health [AI52230]
FX Funding for this research was generously provided by the National
Institutes of Health (AI52230). We thank Dr Martin Smilkstein (Portland
Veterans Affairs Medical Center) for performing the in vitro
antimalarial assay.
NR 16
TC 24
Z9 24
U1 0
U2 5
PU PERGAMON-ELSEVIER SCIENCE LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
SN 0960-894X
J9 BIOORG MED CHEM LETT
JI Bioorg. Med. Chem. Lett.
PD DEC 15
PY 2008
VL 18
IS 24
BP 6402
EP 6405
DI 10.1016/j.bmcl.2008.10.097
PG 4
WC Chemistry, Medicinal; Chemistry, Organic
SC Pharmacology & Pharmacy; Chemistry
GA 375VE
UT WOS:000261141100022
PM 18996691
ER
PT J
AU Hashisho, Z
Emamipour, H
Rood, MJ
Hay, KJ
Kim, BJ
Thurston, D
AF Hashisho, Zaher
Emamipour, Hamidreza
Rood, Mark J.
Hay, K. James
Kim, Byung J.
Thurston, Deborah
TI Concomitant Adsorption and Desorption of Organic Vapor in Dry and Humid
Air Streams using Microwave and Direct Electrothermal Swing Adsorption
SO ENVIRONMENTAL SCIENCE & TECHNOLOGY
LA English
DT Article
ID CARBON LOAD EQUALIZATION; ACTIVATED CARBON; BIOFILTRATION; TOLUENE;
CLOTH; BIOFILTER; REMOVAL; CAPTURE
AB Industrial gas streams can contain highly variable organic vapor concentrations that need to be processed before they are emitted to the atmosphere. Fluctuations in organic vapor concentrations make it more difficult to operate a biofilter when compared to a constant vapor concentration. Hence, there is a need to stabilize the concentration of rapidly fluctuating gas streams for optimum operation of biofilters. This paper describes new concomitant adsorption desorption (CAD) systems used with variable organic vapor concentration gas streams to provide the same gas stream, but at a user-selected constant vapor concentration that can then be more readily processed by a secondary air pollution control device such as a biofilter. The systems adsorb organic vapor from gas streams and simultaneously heat the adsorbent using microwave or direct electrothermal energy to desorb the organic vapor at a user-selected set-point concentration. Both systems depicted a high degree of concentration stabilization with a mean relative deviation between set-point and stabilized concentration of 0.3-0.4%. The direct electrothermal CAD system was also evaluated to treat a humid gas stream (relative humidity = 85%) that contained a variable organic vapor concentration. The high humidity did not interfere with CAD operation as water vapor did not adsorb but penetrated through the adsorbent These results are important because they demonstrate the ability of CAD to effectively dampen concentration fluctuation in gas streams.
C1 [Hashisho, Zaher] Univ Alberta, Dept Civil & Environm Engn, Edmonton, AB T6G 2W2, Canada.
[Emamipour, Hamidreza; Rood, Mark J.; Thurston, Deborah] Univ Illinois, Dept Civil & Environm Engn, Urbana, IL 61801 USA.
[Hay, K. James; Kim, Byung J.] USA, Construct Engn Res Lab, Ctr Res Dev & Engn, Champaign, IL 61826 USA.
RP Hashisho, Z (reprint author), Univ Alberta, Dept Civil & Environm Engn, Edmonton, AB T6G 2W2, Canada.
EM hashisho@ualberta.ca
FU Department of Defense [W9132T-04-2-0006, A5639 FA8651-04-1-0004];
National Science Foundation [DMI-02-17491, BES-05-04385]
FX Financial support is acknowledged from the Department of Defense under
contracts W9132T-04-2-0006 and A5639 FA8651-04-1-0004, and from the
National Science Foundation grants DMI-02-17491 and BES-05-04385.
NR 23
TC 16
Z9 16
U1 1
U2 16
PU AMER CHEMICAL SOC
PI WASHINGTON
PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
SN 0013-936X
J9 ENVIRON SCI TECHNOL
JI Environ. Sci. Technol.
PD DEC 15
PY 2008
VL 42
IS 24
BP 9317
EP 9322
DI 10.1021/es801285v
PG 6
WC Engineering, Environmental; Environmental Sciences
SC Engineering; Environmental Sciences & Ecology
GA 383MX
UT WOS:000261678800052
PM 19174910
ER
PT J
AU Qin, WD
Li, J
Kou, H
Gu, X
Kecskes, L
Chang, H
Zhou, L
AF Qin, Weidong
Li, Jinshan
Kou, Hongchao
Gu, Xiaofeng
Kecskes, Laszlo
Chang, Hui
Zhou, Lian
TI Effects of Zn addition on the improvement of glass forming ability and
plasticity of Mg-Cu-Tb bulk metallic glasses
SO JOURNAL OF NON-CRYSTALLINE SOLIDS
LA English
DT Article
DE Alloys; Glass formation
ID ALLOYS; COMPOSITES; TRANSITION; VISCOSITY; STRENGTH; LIQUIDS; GD
AB The effects of Zn addition on the glass forming ability and mechanical properties of Mg(65)Cu(25-x)Zn(x)Tb(10) (x = 0, 2.5, 5, and 7.5) have been investigated. We show that small amounts of Zn addition improve the glass forming ability, strength, and ductility of the Mg-Cu-Tb bulk metallic glass. For the best glass forming composition, amorphous rods of Mg(65)Cu(20)Zn(5)Tb(10) with a diameter of at least 7 mm have been prepared by a conventional copper mold casting method. Additionally, this composition exhibits obvious yielding and plastic deformation upon quasi-static compressive loading. The fracture strength. total strain to failure, and the plastic strain of the Mg(65)Cu(20)Zn(5)Tb(10) bulk metallic glass reaches 1025 MPa, 2.05% and 0.15%, respectively. This is significantly superior compared to that exhibited by the original Zn-free Mg-Cu-Tb amorphous alloy. (C) 2008 Elsevier B.V. All rights reserved.
C1 [Qin, Weidong; Li, Jinshan; Kou, Hongchao; Chang, Hui; Zhou, Lian] NW Polytech Univ, State Key Lab Solidificat Proc, Xian 710072, Peoples R China.
[Gu, Xiaofeng] Jiangnan Univ, Sch Informat Technol, Wuxi 214122, Jiangsu, Peoples R China.
[Kecskes, Laszlo] USA, Res Lab, Div Mat, Aberdeen Proving Ground, MD 21005 USA.
RP Qin, WD (reprint author), NW Polytech Univ, State Key Lab Solidificat Proc, 127 Youyixi Road, Xian 710072, Peoples R China.
EM qinweidong2000@yahoo.com.cn
RI Gu, Xiaofeng/E-8287-2013; Kecskes, Laszlo/F-6880-2014;
OI Gu, Xiaofeng/0000-0001-8299-6451; Kecskes, Laszlo/0000-0002-1342-3729;
KOU, Hongchao/0000-0003-4960-9477; Li, Jinshan/0000-0002-6894-9760
FU National Natural Science Foundation of China [50601011, 50432020];
Fundamental Research Project of National Defense of China [A
2720060295]; NSF of Jiangsu Province Program for NCETs in University and
Science [BK2006533]; DPOP in Northwestern Polytechnical University
FX This work is supported by National Natural Science Foundation of China
(Nos. 50601011, 50432020), Fundamental Research Project of National
Defense of China (A 2720060295), NSF of Jiangsu Province (BK2006533),
Program for NCETs in University and Science, and DPOP in Northwestern
Polytechnical University.
NR 26
TC 6
Z9 7
U1 0
U2 5
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0022-3093
J9 J NON-CRYST SOLIDS
JI J. Non-Cryst. Solids
PD DEC 15
PY 2008
VL 354
IS 52-54
BP 5368
EP 5371
DI 10.1016/j.jnoncrysol.2008.09.032
PG 4
WC Materials Science, Ceramics; Materials Science, Multidisciplinary
SC Materials Science
GA 383YP
UT WOS:000261710700005
ER
PT J
AU Bairavarasu, SR
Edwards, ME
Sastry, MD
Kochary, F
Kommidi, P
Reddy, BR
Lianos, D
Aggarwal, MD
AF Bairavarasu, Sundar R.
Edwards, Matthew E.
Sastry, Medury D.
Kochary, Faris
Kommidi, Praveena
Reddy, B. Rami
Lianos, Dimitrious
Aggarwal, Manmohan D.
TI Photomagnetism and photoluminescence (PL) of (Pb-Fe-e(-)) complex in
lead magnesium niobate-lead titanate (PMN-PT) crystals containing
beta-PbO nanoclusters
SO SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
LA English
DT Article
DE PMN-PT; Photoluminescence; Magnetic polaron
ID SINGLE-CRYSTALS; RESONANCE; TEMPERATURE; DEFECTS; EPR
AB We present electron paramagnetic resonance (EPR)-evidence of photomagnetism under the conditions of in situ green laser illumination (photo-EPR) in lead magnesium niobate-lead titanate, Pb(Mg,Nb)O(3)-PbTiO(3) (PMN-PT), containing nanoparticles/wires of orthorhombic beta-PbO as identified by Raman spectroscopy. Photo-EPR studies of the sample containing beta-PbO, brownish red in color, have shown intense line at g=2.00, and its yield increased when produced in the presence of 7.5 kG external magnetic field suggesting the formation of magnetic polaron. This was identified as due to interaction between Fe(3+), photoinduced Pb(3+) and unpaired electron trapped at oxygen vacancies. The photoinduced growth and decay of magnetic polaron has shown a non-exponential behavior. Photoluminescence (PL) studies were conducted with excitation at 308 nm (XeCl laser) and also at 454.5,488 and 514.5 nm using At(+) laser. The excitation with 308 nm gave broad PL centered at 500 and 710 nm the latter being quite prominent in beta-PbO containing crystals, along with cooperative luminescence at 350 nm involving two emitting centers. The excitation with Ar(+) laser lines, close to the electronic absorption in samples containing beta-PbO gave richer and sharp PL emission in red region from the constituents of the magnetic polaron and also intense anti-Stokes emission on excitation with 514.5 nm radiation. This appears to be due to phototransfer optically stimulated luminescence (PT-OSL) involving electron-hole recombination at photoinduced magnetic polaron site. (C) 2008 Elsevier B.V. All rights reserved.
C1 [Bairavarasu, Sundar R.; Edwards, Matthew E.; Sastry, Medury D.; Kochary, Faris; Kommidi, Praveena; Reddy, B. Rami; Aggarwal, Manmohan D.] Alabama A&M Univ, Dept Phys, Normal, AL 35762 USA.
[Lianos, Dimitrious] USA, Space & Missile Def Command, Huntsville, AL 35805 USA.
RP Bairavarasu, SR (reprint author), Alabama A&M Univ, Dept Phys, Normal, AL 35762 USA.
EM sundarbairavarasu@gmail.com
FU U.S. Army Missile and Defense [W9113M-04-C-0005]; HBCU-RISE National
Science Foundation [HRD-0531183]; NASA Administrator's Fellowship
Program (NAFP); United Negro College Fund Special Programs
(UNCFSP)Corporation [NNG06GC58A]
FX This work was supported by U.S. Army Missile and Defense contract
#W9113M-04-C-0005 and HBCU-RISE National Science Foundation HRD-0531183
project. Authors wish to thank Dr. Josh Herring of the Department of
Food Science, for his help with electron microscopy measurements. Thanks
are also due to Sandesh Mane and Mahesh Gaonkar GII, Mumbai, for
recording Raman and FT-IR spectra. One of the authors (MDA) would like
to acknowledge the support from NASA Administrator's Fellowship Program
(NAFP) through United Negro College Fund Special Programs
(UNCFSP)Corporation under their contract #NNG06GC58A.
NR 40
TC 2
Z9 2
U1 1
U2 9
PU PERGAMON-ELSEVIER SCIENCE LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
SN 1386-1425
J9 SPECTROCHIM ACTA A
JI Spectroc. Acta Pt. A-Molec. Biomolec. Spectr.
PD DEC 15
PY 2008
VL 71
IS 4
BP 1581
EP 1587
DI 10.1016/j.saa.2008.06.004
PG 7
WC Spectroscopy
SC Spectroscopy
GA 377KC
UT WOS:000261249100068
PM 18644744
ER
PT J
AU Cardoso, MJ
Dmitriev, AE
Helgeson, M
Lehman, RA
Kuklo, TR
Rosner, MK
AF Cardoso, Mario J.
Dmitriev, Anton E.
Helgeson, Melvin
Lehman, Ronald A.
Kuklo, Timothy R.
Rosner, Michael K.
TI Does Superior-Segment Facet Violation or Laminectomy Destabilize the
Adjacent Level in Lumbar Transpedicular Fixation?
SO SPINE
LA English
DT Article
DE Adjacent level disease; facet violation; laminectomy; transpedicular
lumbar fixation
ID PEDICLE SCREW FIXATION; INTERBODY FUSION; JOINT VIOLATION;
SPINAL-FUSION; FOLLOW-UP; INSTRUMENTATION; COMPLICATIONS; DEGENERATION;
INSTABILITY; SPONDYLOLISTHESIS
AB Study Design. This is an in vitro biomechanical study.
Objective. The current investigation was performed to evaluate adjacent level kinematic change following unilateral and bilateral facet violation and laminectomy following 1-, 2-, and 3-level reconstruction.
Summary of Background Data. The incidence of superior-segment facet violation with lumbar transpedicular fixation has been reported as high as 35%; however, its contribution to biomechanical instability at the supradjacent level is unknown. In addition, superior-segment laminectomy has been implicated as a risk factor for the development of adjacent level disease. The authors assess the acute biomechanical effects of proximal facet violation and subsequent laminectomy in an instrumented posterior fusion model in 10 cadaveric specimens.
Methods. Biomechanical testing was performed on 10 human cadaveric spines under axial rotation (AR), flexion-extension (FE), and lateral bending (LB) loading. After intact analysis, pedicle screws were inserted from L5-S1 and testing repeated with: (1) preserved L4-L5 facets, (2) unilateral facet breach, (3) bilateral breach, and (4) L5 laminectomy. Following biomechanical analysis, instrumentation was extended to L4, then L3 and biomechanical testing repeated. Full range of motion (ROM) at the proximal adjacent levels were recorded and normalized to intact (100%).
Results. Supradjacent level ROM was increased for all groups under all loading methods relative to intact (P < 0.05). However, AR testing revealed progressive instability at the adjacent level in groups 3 and 4, relative to group 1, following 1-, 2- and 3-level fixation (P < 0.05). During FE, supradjacent level ROM was significantly increased for group 4 specimens compared with group 1 after L5-S1 fixation (P < 0.05), and was greater than all other groups for L3-S1 constructs (P < 0.05). Interestingly, under lateral bending, facet joint destabilization did not change adjacent segment ROM.
Conclusion. There were significant changes in proximal level ROM immediately after posterior stabilization. However, an additional increase in supradjacent segment ROM was recorded during AR after bilateral facet breach. Subsequent complete laminectomy at the uppermost-fixation level further destabilized the supradjacent segment in FE and AR. Therefore, meticulous preservation of the cephalad-most segment facet joints-is paramount to ensure stability.
C1 [Cardoso, Mario J.; Rosner, Michael K.] Walter Reed Army Med Ctr, Neurosurg Serv, Washington, DC 20307 USA.
[Dmitriev, Anton E.; Helgeson, Melvin; Lehman, Ronald A.] Walter Reed Army Med Ctr, Dept Orthoped & Rehabil, Washington, DC 20307 USA.
[Kuklo, Timothy R.] WA Univ St Louis, Dept Orthoped Surg, St Louis, MO USA.
RP Cardoso, MJ (reprint author), Walter Reed Army Med Ctr, Neurosurg Serv, 6900 Georgia Ave NW, Washington, DC 20307 USA.
EM mtcardoso@comcast.net
NR 31
TC 31
Z9 39
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0362-2436
J9 SPINE
JI SPINE
PD DEC 15
PY 2008
VL 33
IS 26
BP 2868
EP 2873
DI 10.1097/BRS.0b013e31818c63d3
PG 6
WC Clinical Neurology; Orthopedics
SC Neurosciences & Neurology; Orthopedics
GA 405YT
UT WOS:000263260800004
PM 19092616
ER
PT J
AU Noedl, H
Se, Y
Schaecher, K
Smith, BL
Socheat, D
Fukuda, MM
AF Noedl, Harald
Se, Youry
Schaecher, Kurt
Smith, Bryan L.
Socheat, Duong
Fukuda, Mark M.
CA ARC1 Study Consortium
TI Evidence of Artemisinin-Resistant Malaria in Western Cambodia
SO NEW ENGLAND JOURNAL OF MEDICINE
LA English
DT Letter
C1 [Noedl, Harald] Med Univ Vienna, A-1090 Vienna, Austria.
[Se, Youry; Schaecher, Kurt; Smith, Bryan L.; Fukuda, Mark M.] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Socheat, Duong] Natl Ctr Parasitol Entomol & Malaria Control, Phnom Penh, Cambodia.
RP Noedl, H (reprint author), Med Univ Vienna, A-1090 Vienna, Austria.
EM harald.noedl@meduniwien.ac.at
NR 0
TC 692
Z9 710
U1 7
U2 67
PU MASSACHUSETTS MEDICAL SOC
PI WALTHAM
PA WALTHAM WOODS CENTER, 860 WINTER ST,, WALTHAM, MA 02451-1413 USA
SN 0028-4793
J9 NEW ENGL J MED
JI N. Engl. J. Med.
PD DEC 11
PY 2008
VL 359
IS 24
BP 2619
EP 2620
DI 10.1056/NEJMc0805011
PG 2
WC Medicine, General & Internal
SC General & Internal Medicine
GA 381KG
UT WOS:000261534200032
PM 19064625
ER
PT J
AU Eller, LA
Eller, MA
Ouma, B
Kataaha, P
Kyabaggu, D
Tumusiime, R
Wandege, J
Sanya, R
Sateren, WB
Wabwire-Mangen, F
Kibuuka, H
Robb, ML
Michael, NL
de Souza, MS
AF Eller, Leigh Anne
Eller, Michael A.
Ouma, Benson
Kataaha, Peter
Kyabaggu, Denis
Tumusiime, Richard
Wandege, Joseph
Sanya, Ronald
Sateren, Warren B.
Wabwire-Mangen, Fred
Kibuuka, Hannah
Robb, Merlin L.
Michael, Nelson L.
de Souza, Mark S.
TI Reference Intervals in Healthy Adult Ugandan Blood Donors and Their
Impact on Conducting International Vaccine Trials
SO PLOS ONE
LA English
DT Article
AB Background: Clinical trials are increasingly being conducted internationally. In order to ensure enrollment of healthy participants and proper safety evaluation of vaccine candidates, established reference intervals for clinical tests are required in the target population.
Methodology/Principal Findings: We report a reference range study conducted in Ugandan adult blood bank donors establishing reference intervals for hematology and clinical chemistry parameters. Several differences were observed when compared to previously established values from the United States, most notably in neutrophils and eosinophils.
Conclusions/Significance: In a recently conducted vaccine trial in Uganda, 31 percent (n = 69) of volunteers screened (n = 223) were excluded due to hematologic abnormalities. If local reference ranges had been employed, 83% of those screened out due to these abnormalities could have been included in the study, drastically reducing workload and cost associated with the screening process. In addition, toxicity tables used in vaccine and drug trial safety evaluations may need adjustment as some clinical reference ranges determined in this study overlap with grade 1 and grade 2 adverse events.
C1 [Eller, Michael A.; Sateren, Warren B.; Robb, Merlin L.; de Souza, Mark S.] US Mil HIV Res Program, Rockville, MD USA.
[Eller, Leigh Anne; Eller, Michael A.; Ouma, Benson; Kyabaggu, Denis; Tumusiime, Richard; Wandege, Joseph; Sanya, Ronald; Wabwire-Mangen, Fred; Kibuuka, Hannah] Makerere Univ, Walter Reed Project, Kampala, Uganda.
[Kataaha, Peter] Uganda Natl Blood Transfus Serv, Kampala, Uganda.
[Michael, Nelson L.] Walter Reed Army Inst Res, Rockville, MD USA.
[de Souza, Mark S.] Armed Forces Res Inst Med Sci, Bangkok, Thailand.
RP Eller, LA (reprint author), US Mil HIV Res Program, Rockville, MD USA.
EM leller@muwrp.org
FU U.S. Army Medical Research and Materiel Command [W81XWH-04-02-0005];
Henry M. Jackson Foundation for the Advancement of Military Medicine;
DAIDS [1Y-A1-26-42-07]
FX This work was supported by the U.S. Army Medical Research and Materiel
Command and its Cooperative Agreement (W81XWH-04-02-0005) with the Henry
M. Jackson Foundation for the Advancement of Military Medicine and with
an Inter Agency Agreement (1Y-A1-26-42-07) with DAIDS. The funders had
no role in study design, data collection and analysis, decision to
publish, or preparation of the manuscript.
NR 18
TC 25
Z9 26
U1 0
U2 0
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 185 BERRY ST, STE 1300, SAN FRANCISCO, CA 94107 USA
SN 1932-6203
J9 PLOS ONE
JI PLoS One
PD DEC 11
PY 2008
VL 3
IS 12
AR e3919
DI 10.1371/journal.pone.0003919
PG 6
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA 436ZU
UT WOS:000265455900006
PM 19079547
ER
PT J
AU Smith, TA
AF Smith, Troy Alvin
TI Analysis of axisymmetric shell structures under axisymmetric loading by
the flexibility method
SO JOURNAL OF SOUND AND VIBRATION
LA English
DT Article
ID ROTATIONALLY SYMMETRIC SHELLS; FINITE-DIFFERENCE ANALYSIS;
NUMERICAL-ANALYSIS; DYNAMIC-ANALYSIS; REVOLUTION; VIBRATION
AB A method is developed for the static stress and deformation analysis of axisymmetric shells under axisymmetric loading by reduction of the shell to ring sections. In particular, the wall thickness of the shell may vary and the method is applicable to the analysis of shells with irregular meridional geometry. Explicit expressions for the influence coefficients for each ring element are derived. In the development of these expressions, exact evaluation of stresses in the circumferential direction of the ring is used. The distribution of stresses in the meridional direction of the ring element is assumed to be linear with each element. By using the derived influence coefficients, the unknown forces at the junctures of the ring elements are found by the standard flexibility method of indeterminate structural analysis. Subsequently, the displacements and internal stresses are determined. Example solutions for a flat circular plate under transverse loading and for a cylindrical shell under a boundary edge loading show excellent agreement with solutions found by solving the governing differential equations. (c) 2008 Elsevier Ltd. All rights reserved.
C1 USA, Res Dev & Engn Command, Ctr Dev & Engn, Redstone Arsenal, AL 35898 USA.
RP Smith, TA (reprint author), USA, Res Dev & Engn Command, Ctr Dev & Engn, Redstone Arsenal, AL 35898 USA.
NR 33
TC 0
Z9 0
U1 0
U2 1
PU ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD
PI LONDON
PA 24-28 OVAL RD, LONDON NW1 7DX, ENGLAND
SN 0022-460X
J9 J SOUND VIB
JI J. Sound Vibr.
PD DEC 9
PY 2008
VL 318
IS 3
BP 428
EP 460
DI 10.1016/j.jsv.2008.02.056
PG 33
WC Acoustics; Engineering, Mechanical; Mechanics
SC Acoustics; Engineering; Mechanics
GA 356CE
UT WOS:000259755500003
ER
PT J
AU Geisbert, TW
Daddario-DiCaprio, KM
Geisbert, JB
Reed, DS
Feldmann, F
Grolla, A
Stroher, U
Fritz, EA
Hensley, LE
Jones, SM
Feldmann, H
AF Geisbert, Thomas W.
Daddario-DiCaprio, Kathleen M.
Geisbert, Joan B.
Reed, Douglas S.
Feldmann, Friederike
Grolla, Allen
Stroeher, Ute
Fritz, Elizabeth A.
Hensley, Lisa E.
Jones, Steven M.
Feldmann, Heinz
TI Vesicular stomatitis virus-based vaccines protect nonhuman primates
against aerosol challenge with Ebola and Marburg viruses
SO VACCINE
LA English
DT Article
DE Ebola virus; Marburg virus; Filovirus; Nonhuman primates; Aerosol;
Vaccines
ID ATTENUATED RECOMBINANT VACCINE; HEMORRHAGIC-FEVER; POSTEXPOSURE
PROTECTION; EXPERIMENTAL-INFECTION; CYNOMOLGUS MACAQUES; RHESUS-MONKEYS;
VECTORS; LIVE; RESPONSES; STRAINS
AB Considerable progress has been made over the last decade in developing candidate preventive vaccines that can protect nonhuman primates against Ebola and Marburg viruses. A vaccine based oil recombinant vesicular stomatitis virus (VSV) seems to be particularly robust as it can also confer protection when administered as a postexposure treatment. While filoviruses are not thought to be transmitted by aerosol in nature the inhalation route is among the most likely portals of entry ill the setting of a bioterrorist event. At present, all candidate filoviral vaccines have been evaluated against parenteral challenges but none have been tested against an aerosol exposure. Here, we evaluated our recombinant VSV-based Zaire ebolavirus (ZEBOV) and Marburg Virus (MARV) vaccines against aerosol challenge ill cynomolgus macaques. All monkeys vaccinated with a VSV vector expressing the glycoprotein of ZEBOV were completely protected against an aerosol exposure of ZEBOV. Likewise, all monkeys vaccinated with a VSV vector expressing the glycoprotein of MARV were completely protected against all aerosol exposure of MARV. All control animals challenged by the aerosol route with either ZEBOV or MARV succumbed. Interestingly, disease in control animals appeared to progress slower than previously seen in macaques exposed to comparable doses by intramuscular injection. Published by Elsevier Ltd.
C1 [Geisbert, Thomas W.] Boston Univ, Sch Med, Dept Microbiol, Boston, MA 02118 USA.
[Geisbert, Thomas W.; Geisbert, Joan B.] Boston Univ, Sch Med, Natl Emerging Infect Dis Labs Inst, Boston, MA 02118 USA.
[Geisbert, Thomas W.] Boston Univ, Sch Med, Dept Med, Boston, MA 02118 USA.
[Geisbert, Thomas W.; Daddario-DiCaprio, Kathleen M.] Uniformed Serv Univ Hlth Sci, Dept Pathol, Bethesda, MD 20814 USA.
[Geisbert, Thomas W.; Daddario-DiCaprio, Kathleen M.; Geisbert, Joan B.; Fritz, Elizabeth A.; Hensley, Lisa E.] USA, Med Res Inst Infect Dis, Div Virol, Frederick, MD 21701 USA.
[Reed, Douglas S.] Univ Pittsburgh, Ctr Vaccine Res, Pittsburgh, PA USA.
[Feldmann, Friederike; Grolla, Allen; Stroeher, Ute; Jones, Steven M.; Feldmann, Heinz] Publ Hlth Agcy Canada, Special Pathogens Program, Natl Microbiol Lab, Winnipeg, MB, Canada.
[Stroeher, Ute; Jones, Steven M.; Feldmann, Heinz] Univ Manitoba, Dept Med Microbiol, Winnipeg, MB, Canada.
[Jones, Steven M.] Univ Manitoba, Dept Immunol, Winnipeg, MB, Canada.
RP Geisbert, TW (reprint author), Boston Univ, Sch Med, Dept Microbiol, 715 Albany St,R514, Boston, MA 02118 USA.
EM geisbert@bu.edu
OI Reed, Douglas/0000-0003-0076-9023
FU Defense Threat Reduction Agency [04-4-7J-012]; Public Health Agency of
Canada; Canadian Institutes of Health Research [MOP-39321]; Chemical,
Biological, Radiological, and Nuclear (CBRN) Research and Technology
Initiative (CRTI)
FX From USAMRIID, the authors thank John Crarripton and Carlton Rice for
animal care and Matthew Lackerneyer and Adam Hedge for assistance with
aerosol exposures. From the National Microbiology Laboratory (NML) of
the Public Health Agency of Canada (PHAC) the authors thankJason Gren
and Anders Leung for technical assistance in biocontainment. We are
grateful to John Rose (Yale University) for kindly providing us with the
vesicular stornatitis virus reverse genetics system. Work oil
filoviruses at LISAMRIID was funded by the Defense Threat Reduction
Agency (project number 04-4-7J-012). Work on filoviruses at the National
Microbiology Laboratory was Supported by Public Health Agency of Canada,
a grant awarded to HF from the Canadian Institutes of Health Research
(MOP-39321), and a grant awarded to SMJ from Chemical, Biological,
Radiological, and Nuclear (CBRN) Research and Technology Initiative
(CRTI). Opinions, interpretations, conclusions, and recornmendations are
those of the authors and are not necessarily endorsed by Boston
University, the U.S. Army, or the Public Health Agency of Canada.
NR 41
TC 93
Z9 99
U1 2
U2 14
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
J9 VACCINE
JI Vaccine
PD DEC 9
PY 2008
VL 26
IS 52
BP 6894
EP 6900
DI 10.1016/j.vaccine.2008.09.082
PG 7
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 386QT
UT WOS:000261898400025
PM 18930776
ER
PT J
AU Chandrahalim, H
Bhave, SA
Polcawich, R
Pulskamp, J
Judy, D
Kaul, R
Dubey, M
AF Chandrahalim, Hengky
Bhave, Sunil A.
Polcawich, Ronald
Pulskamp, Jeff
Judy, Daniel
Kaul, Roger
Dubey, Madan
TI Performance comparison of Pb(Zr0.52Ti0.48)O-3-only and
Pb(Zr0.52Ti0.48)O-3-on-silicon resonators
SO APPLIED PHYSICS LETTERS
LA English
DT Article
DE dielectric resonators; lead compounds; micromechanical resonators;
oscillators; Q-factor; radiofrequency filters; silicon; zirconium
compounds
ID PIEZOELECTRIC RESONATORS
AB This paper provides a quantitative comparison and explores the design space of lead zirconium titanate (PZT)-only and PZT-on-silicon length-extensional mode resonators for incorporation into radio frequency microelectromechanical system filters and oscillators. We experimentally measured the correlation of motional impedance (R-X) and quality factor (Q) with the resonators' silicon layer thickness (t(Si)). For identical lateral dimensions and PZT-layer thicknesses (t(PZT)), the PZT-on-silicon resonator has higher resonant frequency (f(C)), higher Q (5100 versus 140), lower R-X (51 Omega versus 205 Omega), and better linearity [third-order input intercept point (IIP3) of +43.7 dBm versus +23.3 dBm]. In contrast, the PZT-only resonator demonstrated much wider frequency tuning range (5.1% versus 0.2%).
C1 [Chandrahalim, Hengky; Bhave, Sunil A.] Cornell Univ, OxideMEMS Lab, Ithaca, NY 14853 USA.
[Polcawich, Ronald; Pulskamp, Jeff; Judy, Daniel; Kaul, Roger; Dubey, Madan] USA, Res Lab, Adelphi, MD 20783 USA.
RP Chandrahalim, H (reprint author), Cornell Univ, OxideMEMS Lab, Ithaca, NY 14853 USA.
EM hc287@cornell.edu
RI Chandrahalim, Hengky/F-1475-2016
OI Chandrahalim, Hengky/0000-0003-1930-1359
NR 13
TC 30
Z9 30
U1 0
U2 5
PU AMER INST PHYSICS
PI MELVILLE
PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1,
MELVILLE, NY 11747-4501 USA
SN 0003-6951
J9 APPL PHYS LETT
JI Appl. Phys. Lett.
PD DEC 8
PY 2008
VL 93
IS 23
AR 233504
DI 10.1063/1.3046717
PG 3
WC Physics, Applied
SC Physics
GA 383UP
UT WOS:000261699700080
ER
PT J
AU Chen, MK
Kim, JH
Yang, CE
Yin, SS
Hui, RQ
Ruffin, P
AF Chen, Meng-Ku
Kim, Jae Hun
Yang, Chia-En
Yin, Stuart Shizhuo
Hui, Rongqing
Ruffin, Paul
TI Terahertz generation in multiple laser-induced air plasmas
SO APPLIED PHYSICS LETTERS
LA English
DT Article
DE plasma production by laser; plasma waves; submillimetre wave generation
ID COHERENT CONTROL
AB An investigation of the terahertz wave generation in multiple laser-induced air plasmas is presented. First, it is demonstrated that the intensity of the terahertz wave increases as the number of air plasmas increases. Second, the physical mechanism of this enhancement effect of the terahertz generation is studied by quantitatively measuring the intensity of the generated terahertz wave as a function of phase difference between adjacent air plasmas. It is found out that the superposition is the main mechanism to cause this enhancement. Thus, the results obtained in this paper not only provide a technique to generate stronger terahertz wave but also enable a better understanding of the mechanism of the terahertz generation in air plasma.
C1 [Chen, Meng-Ku; Kim, Jae Hun; Yang, Chia-En; Yin, Stuart Shizhuo] Penn State Univ, Dept Elect Engn, University Pk, PA 16802 USA.
[Hui, Rongqing] Univ Kansas, Dept Elect Engn & Comp Sci, Lawrence, KS 66045 USA.
[Ruffin, Paul] USA, Aviat & Missile Res Dev & Engn Ctr, Redstone Arsenal, AL 35898 USA.
RP Yin, SS (reprint author), Penn State Univ, Dept Elect Engn, University Pk, PA 16802 USA.
EM muc202@psu.edu; sxy105@psu.edu
OI Kim, Jae-Hun/0000-0001-6537-0350
FU Office of Naval Research [N00014-08-1-0538]
FX Partial financial support of this work by Office of Naval Research
(Grant No. N00014-08-1-0538) is greatly appreciated. The authors also
gratefully acknowledge helpful discussions and technical support from
Zhiwen Liu and Peng Li.
NR 9
TC 15
Z9 15
U1 3
U2 9
PU AMER INST PHYSICS
PI MELVILLE
PA CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1,
MELVILLE, NY 11747-4501 USA
SN 0003-6951
EI 1077-3118
J9 APPL PHYS LETT
JI Appl. Phys. Lett.
PD DEC 8
PY 2008
VL 93
IS 23
AR 231102
DI 10.1063/1.3046122
PG 3
WC Physics, Applied
SC Physics
GA 383UP
UT WOS:000261699700002
ER
PT J
AU Engler, RJM
Nelson, MR
Klote, MM
VanRaden, MJ
Huang, CY
Cox, NJ
Klimov, A
Keitel, WA
Nichol, KL
Carr, WW
Treanor, JJ
AF Engler, Renata J. M.
Nelson, Michael R.
Klote, Mary M.
VanRaden, Mark J.
Huang, Chiung-Yu
Cox, Nancy J.
Klimov, Alexander
Keitel, Wendy A.
Nichol, Kristin L.
Carr, Warner W.
Treanor, John J.
CA Walter Reed Hlth Care Syst Influen
TI Half- vs Full-Dose Trivalent Inactivated Influenza Vaccine (2004-2005)
Age, Dose, and Sex Effects on Immune Responses
SO ARCHIVES OF INTERNAL MEDICINE
LA English
DT Article
ID HEALTH-CARE WORKERS; RANDOMIZED CONTROLLED-TRIAL; LONG-TERM-CARE;
ANTIBODY-RESPONSES; COST-EFFECTIVENESS; ELDERLY PERSONS; WORKING ADULTS;
VIRUS; SERUM; MORTALITY
AB Background: Optimal public health strategies for managing influenza vaccine shortages are not yet defined. Our objective was to determine the effects of age, sex, and dose on the immunogenicity of intramuscular trivalent inactivated vaccine (TIV).
Methods: Healthy adults aged 18 to 64 years, stratified by age (18-49 and 50-64 years) and sex, were randomized to receive full- or half-dose TIV. Hemagglutination inhibition titers against vaccine antigens were measured before and 21 days after immunization. A primary outcome of noninferiority was defined as a difference of less than 20% in the upper 95% confidence interval (CI) of the proportion of subjects with strain-specific hemagglutination inhibition antibody titers of 1:40 or higher after vaccination. Secondary outcomes included geometric mean titers, after vaccination side effects, and occurrences of influenza-like illnesses.
Results: Among previously immunized subjects (N=1114) receiving half- vs full-dose TIV (age, 18-49 years, n=284 [half] and n=274 [full]; and age 50-64 years, n=276 [half] and n=280 [full]), CIs for proportions of subjects with hemagglutination inhibition antibody titers of 1:40 or higher excluded substantial reduction for all antigens in the 18- to 49-year age group and for B/Shanghai/361/2002 (B) and A/Fujian/411/2002 (A/H3N2) in the 50- to 64-year age group. Geometric mean titer in the female 18- to 49-year age group exceeded male responses for all strains: responses to half- dose TIV that were comparable with male full- dose responses for A/ New Caledonia/20/99 (A/H1N1) antigen, 25.4 (95% CI, 20.9-30.9) vs 25.6 (95% CI, 21.3-30.9); A/H3N2 antigen, 60.8 (95% CI, 50.8-72.7) vs 44.1 (95% CI, 37.6-51.8); and B antigen, 64.4 (95% CI, 53.9-76.9) vs 60.7 (95% CI, 51.4-71.7) (findings were similar for the 50- to 64- year age group). Some injection site and systemic reactions (myalgias and/or arthralgias [P<.05], headache [P<.001], and impact of fatigue [P<.05]) were significantly lower in men. The relative risk of medical visits and hospitalizations for influenza-like illnesses were similar in the half- and full- dose groups regardless of age.
Conclusions: Antibody responses to intramuscular half-dose TIV in healthy, previously immunized adults were not substantially inferior to the full- dose vaccine, particularly for ages 18 to 49 years. Significantly higher geometric mean titer responses in women were identified for all ages, regardless of dose or influenza strain. Half-dose vaccination may be an effective strategy for healthy adults younger than 50 years in the setting of an influenza vaccine shortage.
Trial Registration: clinicaltrials.gov Identifier: NCT00283283
C1 [Engler, Renata J. M.] Walter Reed Army Med Ctr, Vaccine Healthcare Ctr Network, Allergy Immunol Dept, Washington, DC 20307 USA.
[VanRaden, Mark J.; Huang, Chiung-Yu] NIAID, NIH, Bethesda, MD 20892 USA.
[Cox, Nancy J.; Klimov, Alexander] Ctr Dis Control & Prevent, Influenza Branch, Atlanta, GA USA.
[Keitel, Wendy A.] Baylor Coll Med, Houston, TX 77030 USA.
[Nichol, Kristin L.] Univ Minnesota, Sch Med, VA Med Ctr, Minneapolis, MN 55455 USA.
[Nichol, Kristin L.] Univ Minnesota, Sch Med, Dept Med, Minneapolis, MN 55455 USA.
[Treanor, John J.] Univ Rochester, Dept Med, Infect Dis Unit, Rochester, NY USA.
RP Engler, RJM (reprint author), Walter Reed Army Med Ctr, Vaccine Healthcare Ctr Network, Allergy Immunol Dept, 6900 Georgia Ave NW,Bldg 41,Ste 21, Washington, DC 20307 USA.
EM renata.engler@gmail.com
FU Office of the Army Surgeon General in collaboration with Walter Reed
Army Medical Center(WRAMC); Healthcare System; North Atlantic Regional
Medical Command; US Army Medical Research and Materiel Command; National
Institute of Allergy and Infectious Diseases; National Institutes of
Health; Influenza Branch of the Centers for Disease Control and
Prevention
FX This study was supported by the Office of the Army Surgeon General in
collaboration with Walter Reed Army Medical Center(WRAMC) and Healthcare
System; the North Atlantic Regional Medical Command; the US Army Medical
Research and Materiel Command; the National Institute of Allergy and
Infectious Diseases, National Institutes of Health; and the Influenza
Branch of the Centers for Disease Control and Prevention.
NR 34
TC 68
Z9 68
U1 0
U2 6
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 515 N STATE ST, CHICAGO, IL 60610-0946 USA
SN 0003-9926
J9 ARCH INTERN MED
JI Arch. Intern. Med.
PD DEC 8
PY 2008
VL 168
IS 22
BP 2405
EP 2414
DI 10.1001/archinternmed.2008.513
PG 10
WC Medicine, General & Internal
SC General & Internal Medicine
GA 380SX
UT WOS:000261486600004
PM 19064822
ER
PT J
AU Drew, C
Bosselman, S
Ziegler, D
AF Drew, Christopher
Bosselman, Suzanne
Ziegler, David
TI Mixed Morphology by the Extrusion of Phase-Separated Blends of a
Melt-Processed Polymer and Polymer Solution
SO JOURNAL OF APPLIED POLYMER SCIENCE
LA English
DT Article
DE block copolymers; compatibilization; composites; phase separation;
self-organization
ID BLOCK-COPOLYMER; MICROEMULSION; PRESSURE; FILMS; RATIO
AB The phase behavior and structure development in immiscible blends of melt-extruded polycaprolactone and a viscous aqueous poly(ethylene oxide) solution were investigated. The coextrusion of an aqueous polymer solution and a molten polymer is a largely unexplored technique and offers exciting potential for creating new materials via the execution of chemical reactions in the aqueous phase. Samples were prepared both with and without a block copolymer acting as a surface-active agent. The resulting morphology was characterized with scanning electron microscopy after the removal of the watersoluble phase. Spheres, rods, fibers, and cocontinuous gyroidal structures were observed, yet the exact phase inversion was not observed, and the changes in the feature shape depended on which component composed the major phase. Significant orientation in the flow direction was observed when the less viscous poly(ethylene oxide) was the major phase, whereas orientation was minimal when polycaprolactone was the major phase. These observations indicate that control of the feature shape and orientation may be accomplished through the control of the viscosity. The spontaneous formation of an outer layer of polycaprolactone in all samples was observed, suggesting that the morphology could be induced by control of the material interaction with the extruder die wall. The inclusion of a diblock copolymer significantly reduced the feature size but did not alter the morphology type. (C) 2008 Wiley Periodicals, Inc. J Appl Polym Sci 110: 2841-2848, 2008
C1 [Drew, Christopher; Bosselman, Suzanne; Ziegler, David] USA, Natick Soldier Res Dev & Engn Ctr, Natick, MA 01760 USA.
RP Drew, C (reprint author), USA, Natick Soldier Res Dev & Engn Ctr, Kansas St, Natick, MA 01760 USA.
EM christopher.p.drew@us.army.mil
FU Natick Soldier Research; Development and Engineering Center-In-House
Laboratory Independent Research
FX Contract grant sponsor: Natick Soldier Research, Development and
Engineering Center-In-House Laboratory Independent Research.
NR 26
TC 0
Z9 0
U1 2
U2 5
PU JOHN WILEY & SONS INC
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN, NJ 07030 USA
SN 0021-8995
J9 J APPL POLYM SCI
JI J. Appl. Polym. Sci.
PD DEC 5
PY 2008
VL 110
IS 5
BP 2841
EP 2848
DI 10.1002/app.28799
PG 8
WC Polymer Science
SC Polymer Science
GA 361BP
UT WOS:000260102800041
ER
PT J
AU Ramsey, JJ
Pan, E
Chung, PW
AF Ramsey, J. J.
Pan, E.
Chung, P. W.
TI Modelling of strain fields in quantum wires with continuum methods and
molecular statics
SO JOURNAL OF PHYSICS-CONDENSED MATTER
LA English
DT Article
ID ELASTIC PROPERTIES; SIMULATION; DYNAMICS; SEMICONDUCTORS; PROFILES;
GROWTH; SCALE; INAS; DOTS
AB The maximum and minimum principal strains of an InAs quantum wire (QWR) buried in a GaAs matrix are computed using the boundary element method (BEM), the inclusion method, and molecular statics, and the results from each method are compared with each other. The first two methods are based on continuum mechanics and linear elasticity, while the third is atomistic. The maximum principal strains are largely in agreement among the different methods, especially outside the QWR, though in the centre of the QWR, the discrepancy between the continuum and atomistic methods can be as large as 11.9%. The gradients of the strain tensor are in agreement among the methods. The inclusion method is faster than the BEM, and both continuum methods are an order of magnitude faster than molecular statics. Although the inclusion method, unlike the BEM, ignores the difference in material properties between the QWR and its surrounding matrix, its results are in better agreement with the molecular statics results than the results from the BEM. The rough quantitative and qualitative agreements indicate the utility of classical continuum methods for estimating strain profiles in nanoscale structures.
C1 [Ramsey, J. J.; Pan, E.] Univ Akron, Dept Civil Engn, Akron, OH 44325 USA.
[Ramsey, J. J.; Pan, E.] Univ Akron, Dept Appl Math, Akron, OH 44325 USA.
[Chung, P. W.] USA, Ballist Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Ramsey, JJ (reprint author), Univ Akron, Dept Civil Engn, 302 E Buchtel Mall, Akron, OH 44325 USA.
EM jjr19@uakron.edu; pan2@uakron.edu; pchung@arl.army.mil
RI Pan, Ernian/F-4504-2011
OI Pan, Ernian/0000-0001-6640-7805
FU Defense Threat Reduction Agency Joint Science and Technology Office
(DTRA-JSTO) [W911NF-06-2-0038]
FX This work was supported by the Defense Threat Reduction Agency Joint
Science and Technology Office (DTRA-JSTO) under the grant
W911NF-06-2-0038. Also, while the final molecular statics calculations
were done on our own PCs, preliminary molecular statics calculations
were supported in part by an allocation of computing time from the Ohio
Supercomputing Center.
NR 34
TC 3
Z9 3
U1 0
U2 3
PU IOP PUBLISHING LTD
PI BRISTOL
PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND
SN 0953-8984
J9 J PHYS-CONDENS MAT
JI J. Phys.-Condes. Matter
PD DEC 3
PY 2008
VL 20
IS 48
AR 485215
DI 10.1088/0953-8984/20/48/485215
PG 12
WC Physics, Condensed Matter
SC Physics
GA 370JP
UT WOS:000260758800025
ER
PT J
AU Miklossy, J
Steele, JC
Yu, S
McCall, S
Sandberg, G
McGeer, EG
McGeer, PL
AF Miklossy, Judith
Steele, John C.
Yu, Sheng
McCall, Sherman
Sandberg, Glenn
McGeer, Edith G.
McGeer, Patrick L.
TI Enduring involvement of tau, beta-amyloid, alpha-synuclein, ubiquitin
and TDP-43 pathology in the amyotrophic lateral
sclerosis/parkinsonism-dementia complex of Guam (ALS/PDC)
SO ACTA NEUROPATHOLOGICA
LA English
DT Article
DE Alzheimer's disease; alpha-Synuclein; beta-Amyloid protein; Coiled body;
Neurofibrillary tangles; Parkinsonism; Tau; TDP-43
ID PROGRESSIVE SUPRANUCLEAR PALSY; PARKINSONISM-DEMENTIA;
ALZHEIMERS-DISEASE; NEUROFIBRILLARY TANGLES; NEURODEGENERATIVE
DISORDERS; A-BETA; CLINICAL-FEATURES; ENDEMIC DISEASE; SCLEROSIS;
PROTEIN
AB Guam ALS/PDC is a severe tangle forming disorder endemic to Guam with features overlapping such neurodegenerative disorders as Alzheimer disease (AD), Parkinson disease (PD), progressive supranuclear palsy (PSP), ALS, corticobasal degeneration (CBD) and pallido-ponto-nigral degeneration (PPND). Since the prevalence is declining, we examined brain tissue from 35 clinically diagnosed Chamorro patients with ALS/PDC and two Chamorro controls autopsied between 1946 and 2006, to determine if distinct variations in the pathology could be identified up to this time. Although the age at autopsy increased by 4.5-5 years per decade, we identified no qualitative differences in pathological deposits with antibodies against tau, ubiquitin, A beta, alpha-synuclein and TDP-43, indicating that these more recently identified proteins have been involved in the neuropathogenesis over the past 6 decades. Tau and TDP-43 positive neuronal, oligodendroglial and astrocytic inclusions involving multiple nerve fiber tracts occurred in both the ALS and PDC types, reinforcing the concept that these forms are part of the same disorder. The results obtained may help to define the commonality of the Guam disease with other tangle forming disorders and may help in monitoring the epidemiological changes that are taking place.
C1 [Miklossy, Judith; Yu, Sheng; McGeer, Edith G.; McGeer, Patrick L.] Univ British Columbia, Kinsmen Lab Neurol Res, Vancouver, BC V6T IZ3, Canada.
[Steele, John C.] Guam Mem Hosp, Tamuning, GU USA.
[McCall, Sherman] USA, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA.
[Sandberg, Glenn] Armed Forces Inst Pathol, Washington, DC 20306 USA.
RP McGeer, PL (reprint author), Univ British Columbia, Kinsmen Lab Neurol Res, 2255 Wesbrook Mall, Vancouver, BC V6T IZ3, Canada.
EM mcgeerpl@interchange.ubc.ca
FU Pacific Alzheimer Research Foundation
FX This paper was supported by a Grant from the Pacific Alzheimer Research
Foundation. We thank H. Akiyama, L. Binder, B. Giasson, H. Mori and K.
Obi for their generous gifts of key antibodies and H. Martin and J. P.
Guo for technical assistance in preparing figures.
NR 45
TC 39
Z9 39
U1 0
U2 3
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0001-6322
J9 ACTA NEUROPATHOL
JI Acta Neuropathol.
PD DEC
PY 2008
VL 116
IS 6
BP 625
EP 637
DI 10.1007/s00401-008-0439-2
PG 13
WC Clinical Neurology; Neurosciences; Pathology
SC Neurosciences & Neurology; Pathology
GA 374EH
UT WOS:000261025200005
PM 18843496
ER
PT J
AU Seyedabbasi, MA
Farthing, MW
Imhoff, PT
Miller, CT
AF Seyedabbasi, Mir Ahmad
Farthing, Matthew W.
Imhoff, Paul T.
Miller, Cass T.
TI The influence of wettability on NAPL dissolution fingering
SO ADVANCES IN WATER RESOURCES
LA English
DT Article
DE Nonaqueous phase liquids; Mass transfer; Preferential flow; Upscaling
ID NONAQUEOUS PHASE LIQUID; SATURATED POROUS-MEDIA; MASS-TRANSFER RATES;
FRACTIONAL WETTABILITY; HYDRAULIC CONDUCTIVITY; RESIDUAL
TETRACHLOROETHYLENE; RELATIVE PERMEABILITIES; SUBSURFACE SYSTEMS; MODEL;
2-FLUID
AB Laboratory experiments and numerical simulations in homogeneous porous media were used to investigate the influence of porous medium wettability on the formation and growth of preferential dissolution pathways, dissolution fingers, during nonaqueous phase liquid (NAPL) dissolution. As the porous medium became increasingly NAPL-wet, dissolution fingers grew wider and slower. This result was observed in physical experiments with 0% and 100% NAPL-wet conditions and confirmed with numerical simulations at these and intermediate wettabilities. A previously derived expression for an upscaled mass transfer rate coefficient that accounts for the growth of dissolution fingers was used to quantify the effect of fingering on overall NAPL removal rates. For the test cases evaluated, NAPL dissolution fingering controlled the overall rate of NAPL dissolution after the dissolution front moved 4 cm, in 0% NAPL-wet conditions and 18 cm in 100% NAPL-wet conditions. Thus, even in completely NAPL-wet media dissolution fingering may control the overall rate of NAPL dissolution after relatively short travel distances. The importance of NAPL dissolution fingering in heterogeneous systems with spatially varying NAPL saturations, though, remains an important question for future work. (c) 2008 Elsevier Ltd. All rights reserved.
C1 [Seyedabbasi, Mir Ahmad; Imhoff, Paul T.] Univ Delaware, Dept Civil & Environm Engn, Newark, DE 19716 USA.
[Farthing, Matthew W.] USA, Engineer Res & Dev Ctr, Coastal & Hydraul Lab, Vicksburg, MS USA.
[Miller, Cass T.] Univ N Carolina, Dept Environm Sci & Engn, Chapel Hill, NC 27515 USA.
RP Imhoff, PT (reprint author), Univ Delaware, Dept Civil & Environm Engn, 301 DuPont Hall, Newark, DE 19716 USA.
EM ahmad@udel.edu; matthew.w.farthing@erdc.usace.army.mil; imhoff@udel.edu;
casey_mil-ler@unc.edu
RI Miller, Cass T./I-6613-2012
OI Miller, Cass T./0000-0001-6082-9273
FU National Science Foundation [0440236]
FX Nathan Kiracofe provided considerable assistance in relative
permeability measurements at the University of Delaware. For the
numerical simulations permission was granted by the Chief of Engineers
to publish this information. This work was supported by National Science
Foundation Grant 0440236.
NR 44
TC 14
Z9 14
U1 0
U2 6
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0309-1708
J9 ADV WATER RESOUR
JI Adv. Water Resour.
PD DEC
PY 2008
VL 31
IS 12
BP 1687
EP 1696
DI 10.1016/j.advwatres.2008.08.003
PG 10
WC Water Resources
SC Water Resources
GA 388NP
UT WOS:000262026800013
ER
PT J
AU Orio, PF
Merick, GS
Grimm, P
Blasko, J
Sylvester, J
Allen, ZA
Butler, WM
Chaudhry, UUH
AF Orio, Peter F., III
Merick, Gregory S.
Grimm, Peter
Blasko, John
Sylvester, John
Allen, Zachariah A.
Butler, Wayne M.
Chaudhry, Usman-ul-Haq
TI Effects of the Time Interval Between Prostate Brachytherapy and
Postimplant Dosimetric Evaluation in Community Practice Analysis of the
Pro-Qura Database
SO AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
LA English
DT Article
DE prostate; brachytherapy; quality; dosimetry
ID EDEMA; I-125; IMPLANTS; IMPACT; PD-103; CANCER; DEPENDENCE; CARCINOMA;
OUTCOMES; QUALITY
AB Objective: To evaluate the influence of postimplant dosimetric timing on prostate brachytherapy quality in community practice.
Materials and Methods: The Pro-Qura database was stratified by multiple time intervals between the implant and postimplant dosimetric analysis. Postimplant dosimetry was performed in a standardized fashion. Criteria for implant adequacy included V-100 >80%, D-90 >90%, and V-150 <60% for I-125 and <75% for Pd-103. Implants with V-100 <80% and D-90 <90% were deemed "too cool." Implants were considered "too hot" if D-90 >140% of prescription dose and/or V-150 >150% for I-125 and >75% for Pd-103.
Results: For I-125, the average V-100 and D-90 increased from 88.6% to 89.8%, and 102.8% to 103.1 % for day 0 and day 30 dosimetry. For Pd-103 implants the change was more pronounced, with V-100 and D-90 increasing front 81.6% to 87.8% (P < 0.001) and 88.7% to 100.0% (P < 0.001) for day 0, and day 30, respectively. The percentage of implants considered too cool based on a V-100 and D-90 criteria decreased from 18.8% and 26.9% on day 0 to 11.0% and 19.7% on day 30, respectively. Implants determined to be too hot based on a V-150 >60% (I-125)/>75% (Pd-103) or D-90 >140% were 16.4% and 2.2% on day 0 and 16.0% and 0.7% on day 30, respectively.
Conclusion: In community-based brachytherapy programs, postimplant dosimetry performed at day 30 resulted in a statistically and clinically significant improvement in postimplant dosimetry cornpared with day 0. The influence of timing is Substantially greater for Pd-103 than I-125.
C1 [Merick, Gregory S.] Wheeling Hosp, Schiffler Canc Ctr, Wheeling, WV 26003 USA.
[Merick, Gregory S.; Allen, Zachariah A.; Butler, Wayne M.; Chaudhry, Usman-ul-Haq] Wheeling Jesuit Univ, Wheeling, WV USA.
[Orio, Peter F., III] Brooke Army Med Ctr, Dept Radiat Oncol, Ft Sam Houston, TX 78234 USA.
[Grimm, Peter; Blasko, John; Sylvester, John] Swedish Med Ctr, Seattle Prostate Inst, Seattle, WA USA.
RP Merick, GS (reprint author), Wheeling Hosp, Schiffler Canc Ctr, 1 Med Pk, Wheeling, WV 26003 USA.
EM gmerrick@urologicresearchinstitute.org
NR 28
TC 2
Z9 2
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0277-3732
EI 1537-453X
J9 AM J CLIN ONCOL-CANC
JI Am. J. Clin. Oncol.-Cancer Clin. Trials
PD DEC
PY 2008
VL 31
IS 6
BP 523
EP 531
DI 10.1097/COC.0b013e31816fc95a
PG 9
WC Oncology
SC Oncology
GA 382CN
UT WOS:000261582700001
PM 19060582
ER
PT J
AU Nevin, RL
Carbonell, I
Thurmond, V
AF Nevin, Remington L.
Carbonell, Ivan
Thurmond, Veronica
TI Device-specific rates of needlestick injury at a large military teaching
hospital
SO AMERICAN JOURNAL OF INFECTION CONTROL
LA English
DT Article
ID HEALTH-CARE WORKERS
AB The device-specific needlestick injury (NSI) rate provides a means of comparing rates of injury between work sites and institutions over time. We performed a retrospective study of intravenous and percutaneous injection NSI at a large military teaching hospital using electronic purchase records and occupational NSI exposure forms to define action levels for process improvements. A rate of 2.25 NSI per 100,000 intravenous needles and 2.21 NSI per 100,000 percutaneous needles was found. (Am J infect Control 2008;36:750-2.)
C1 [Nevin, Remington L.] USA, Silver Spring, MD 20910 USA.
[Carbonell, Ivan] Walter Reed Army Med Ctr, Occupat Hlth Clin, Washington, DC 20307 USA.
[Thurmond, Veronica] Womack Army Med Ctr, Dept Res, Ft Bragg, NC USA.
RP Nevin, RL (reprint author), USA, 2900 Linden Lane,Suite 200, Silver Spring, MD 20910 USA.
EM remington.nevin@us.army.mil
OI Nevin, Remington/0000-0002-0534-1889
NR 10
TC 1
Z9 1
U1 0
U2 0
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0196-6553
J9 AM J INFECT CONTROL
JI Am. J. Infect. Control
PD DEC
PY 2008
VL 36
IS 10
BP 750
EP 752
DI 10.1016/j.ajic.2008.02.006
PG 3
WC Public, Environmental & Occupational Health; Infectious Diseases
SC Public, Environmental & Occupational Health; Infectious Diseases
GA 385FY
UT WOS:000261801300012
PM 18834746
ER
PT J
AU Mcllwain, DS
Gates, K
Ciliax, D
AF Mcllwain, D. Scott
Gates, Kathy
Ciliax, Donald
TI Heritage of Army Audiology and the Road Ahead: The Army Hearing Program
SO AMERICAN JOURNAL OF PUBLIC HEALTH
LA English
DT Article
AB Noise-induced hearing loss has been documented as early as the 16th century, when a French surgeon, Ambroise Pare, wrote of the treatment of injuries sustained by firearms and described acoustic trauma in great detail. Even so, the protection of hearing would not be addressed for three more centuries, when the jet engine was invented and resulted in a long overdue whirlwind of policy development addressing the prevention of hearing loss.
We present a synopsis of hearing loss prevention in the US Army and describe the current Army Hearing Program, which aims to prevent noise-induced hearing loss in soldiers and to ensure their maximum combat effectiveness. (Am J Public Health. 2008;98:2167-2172. doi:10.2105/AJPH.2007.128504)
C1 [Mcllwain, D. Scott] USA, Dept Med, Ctr & Sch, Dept Prevent Hlth Serv, Ft Sam Houston, TX USA.
[Gates, Kathy] USA, Proponency Off Prevent Med, Falls Church, VA USA.
[Ciliax, Donald] USA, Ctr Hlth Promot & Prevent Med, Aberdeen Proving Ground, MD USA.
RP Mcllwain, DS (reprint author), Hearwell LLC, 6100 Neil Rd,Suite 500, Reno, NV 89511 USA.
EM scott@hearwell.org
NR 20
TC 5
Z9 5
U1 0
U2 1
PU AMER PUBLIC HEALTH ASSOC INC
PI WASHINGTON
PA 800 I STREET, NW, WASHINGTON, DC 20001-3710 USA
SN 0090-0036
EI 1541-0048
J9 AM J PUBLIC HEALTH
JI Am. J. Public Health
PD DEC
PY 2008
VL 98
IS 12
BP 2167
EP 2172
DI 10.2105/AJPH.2007.128504
PG 6
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 378GP
UT WOS:000261309500015
ER
PT J
AU Riddle, MS
Tribble, DR
Putnam, SD
Mostafa, M
Brown, TR
Letizia, A
Armstrong, AW
Sanders, JW
AF Riddle, Mark S.
Tribble, David R.
Putnam, Shannon D.
Mostafa, Manal
Brown, Theodore R.
Letizia, Andrew
Armstrong, Adam W.
Sanders, John W.
TI Past Trends and Current Status of Self-Reported Incidence and Impact of
Disease and Nonbattle Injury in Military Operations in Southwest Asia
and the Middle East
SO AMERICAN JOURNAL OF PUBLIC HEALTH
LA English
DT Article
ID ENDURING FREEDOM; IRAQI FREEDOM; DESERT-SHIELD; US MILITARY; TRAVELERS
DIARRHEA; EPIDEMIOLOGY; POPULATIONS; AFGHANISTAN; PERSONNEL; ETIOLOGY
AB Objectives. To evaluate the evolutional changes in disease and nonbattle injury in a long-term deployment setting, we investigated trends of selected disease and nonbattle injury (NBI) incidence among US military personnel deployed in ongoing military operations in Southwest Asia and the Middle East.
Methods. Participants completed an anonymous questionnaire concerning diarrhea, acute respiratory illness (ARI), and NBIs. We compared incidence, morbidity, and risk associations of disease and NBI incidence with historical data. We analyzed a clinic screening form to describe trends in diarrhea incidence over a 3-year period.
Results. Between April 2006 and March 2007, 3374 troops completed deployment questionnaires. Incidence of diarrhea was higher than that of ARI and NBI (12.1, 7.1, and 2.5 episodes per 100 person-months, respectively), but ARI and NBI resulted in more-frequent health system utilization (both P<.001) and decreased work performance (P<.001 and P=.05, respectively) than did diarrhea. Compared with historical disease and NBI incidence rates, diarrhea and NBI incidence declined over a 4-year period, whereas ARI remained relatively constant.
Conclusions. Diarrhea, ARI, and NBI are important health concerns among deployed military personnel. Public health and preventive measures are needed to mitigate this burden. (Am J Public Health. 2008;98:2199-2206. doi:10.2105/AJPH.2007.131680)
C1 [Riddle, Mark S.] USN, Enter Dis Dept, Med Res Ctr, Silver Spring, MD 20910 USA.
[Tribble, David R.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
[Putnam, Shannon D.] USN, Med Res Unit 2, Jakarta, Indonesia.
[Mostafa, Manal; Armstrong, Adam W.] USN, Med Res Unit 3, Cairo, Egypt.
[Brown, Theodore R.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Letizia, Andrew] Branch Med Clin, Capodichino, Italy.
[Sanders, John W.] USN, Med Res Ctr Detachment, Lima, Peru.
RP Riddle, MS (reprint author), USN, Enter Dis Dept, Med Res Ctr, 503 Robert Grant Ave, Silver Spring, MD 20910 USA.
EM markriddemd@hotmail.com
RI Riddle, Mark/A-8029-2011
FU Military Infectious Disease Research Program and Department of Defense
[6000.Rad1.D.E0301]
FX This study was funded by the Military Infectious Disease Research
Program and Department of Defense under work unit no. 6000.Rad1.D.E0301.
NR 26
TC 22
Z9 22
U1 0
U2 1
PU AMER PUBLIC HEALTH ASSOC INC
PI WASHINGTON
PA 800 I STREET, NW, WASHINGTON, DC 20001-3710 USA
SN 0090-0036
J9 AM J PUBLIC HEALTH
JI Am. J. Public Health
PD DEC
PY 2008
VL 98
IS 12
BP 2199
EP 2206
DI 10.2105/AJPH.2007.131680
PG 8
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 378GP
UT WOS:000261309500022
PM 18923114
ER
PT J
AU Boyle, K
Whittington, J
Deriso, E
Alefantis, T
Bergmann-Leitner, ES
Grewal, P
DelVecchio, V
Angov, E
AF Boyle, Katharine
Whittington, Jessica
Deriso, Elizabeth
Alefantis, Timothy
Bergmann-Leitner, Elke S.
Grewal, Paul
DelVecchio, Vito
Angov, Evelina
TI IMMUNITY INDUCED BY PLASMODIUM BERGHEI CSP EXPRESSION FROM VARIOUS
CELLULAR LOCALIZATIONS AND DELIVERY BY INACTIVATED ESCHERICHIA COLI
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Boyle, Katharine; Deriso, Elizabeth; Bergmann-Leitner, Elke S.; Angov, Evelina] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Whittington, Jessica; Alefantis, Timothy; Grewal, Paul; DelVecchio, Vito] Vital Probes Inc, Mayfield, PA USA.
RI Bergmann-Leitner, Elke/B-3548-2011
OI Bergmann-Leitner, Elke/0000-0002-8571-8956
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 2
BP 1
EP 1
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600003
ER
PT J
AU Patterson, NB
Bruder, JT
Limbach, K
Moretz, SE
Zhou, H
Diouf, A
King, CR
Gowda, K
Chen, P
Konovalova, S
Bergmann-Leitner, ES
Locke, E
Soisson, L
Diggs, C
Angov, E
Long, CA
Richie, TL
Doolan, DL
AF Patterson, Noelle B.
Bruder, Joseph T.
Limbach, Keith
Moretz, Samuel E.
Zhou, Hong
Diouf, Ababacar
King, C. Richter
Gowda, Kalpana
Chen, Ping
Konovalova, Svetlana
Bergmann-Leitner, Elke S.
Locke, Emily
Soisson, Lorraine
Diggs, Carter
Angov, Evelina
Long, Carole A.
Richie, Thomas L.
Doolan, Denise L.
TI THE FIRST GENERATION PLASMODIUM FALCIPARUM AMA-1 BASED MONOVALENT
ADENOVECTOR VACCINE AND THE SECOND GENERATION BIVALENT ADENOVECTOR
VACCINE EXPRESSING PLASMODIUM FALCIPARUM AMA-1 AND MSP1-42 ELICIT ROBUST
FUNCTIONAL ANTIBODIES IN NZW RABBIT
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Patterson, Noelle B.; Limbach, Keith; Gowda, Kalpana; Bergmann-Leitner, Elke S.; Angov, Evelina; Richie, Thomas L.; Doolan, Denise L.] Naval Med Res Ctr, US Mil Malaria Vaccine Program, Silver Spring, MD USA.
[Patterson, Noelle B.; Limbach, Keith; Gowda, Kalpana; Bergmann-Leitner, Elke S.; Angov, Evelina; Richie, Thomas L.; Doolan, Denise L.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Bruder, Joseph T.; King, C. Richter; Chen, Ping; Konovalova, Svetlana] GenVec Inc, Gaithersburg, MD USA.
[Moretz, Samuel E.; Zhou, Hong; Diouf, Ababacar; Long, Carole A.] NIAID, Lab Malaria & Vector Res, NIH, Rockville, MD USA.
[Locke, Emily] PATH Malaria Vaccine Initiat, Bethesda, MD USA.
[Soisson, Lorraine; Diggs, Carter] US Agcy Int Dev, Malaria Vaccine Dev Program, Washington, DC 20523 USA.
RI Bergmann-Leitner, Elke/B-3548-2011; Doolan, Denise/F-1969-2015
OI Bergmann-Leitner, Elke/0000-0002-8571-8956;
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 5
BP 2
EP 2
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600006
ER
PT J
AU Tamminga, C
Chuang, I
Regis, D
Mendoza-Silveiras, J
Epstein, JE
Parekh, F
Reyes, S
Steinbeiss, V
Fedders, C
Maiolatesi, S
Smith, K
Williams, F
Sedegah, M
Doolan, DL
Limbach, K
Patterson, NB
Spring, M
Bruder, JT
King, CR
Soisson, L
Diggs, C
Ockenhouse, CF
Richie, T
AF Tamminga, Cindy
Chuang, Ilin
Regis, David
Mendoza-Silveiras, Jose
Epstein, Judith E.
Parekh, Falgunee
Reyes, Sharina
Steinbeiss, Victoria
Fedders, Charlotte
Maiolatesi, Santina
Smith, Kathryn
Williams, Francis
Sedegah, Martha
Doolan, Denise L.
Limbach, Keith
Patterson, Noelle B.
Spring, Michele
Bruder, Joseph T.
King, C. R.
Soisson, Lorraine
Diggs, Carter
Ockenhouse, Christian F.
Richie, Thomas
TI SAFETY AND TOLERABILITY OF A MULTI-STAGE, MULTI-ANTIGEN
ADENOVIRUS-VECTORED PLASMODIUM FALCIPARUM MALARIA VACCINE, IN HEALTHY,
MALARIA-NAIVE ADULTS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Tamminga, Cindy; Chuang, Ilin; Regis, David; Mendoza-Silveiras, Jose; Epstein, Judith E.; Parekh, Falgunee; Reyes, Sharina; Steinbeiss, Victoria; Fedders, Charlotte; Maiolatesi, Santina; Smith, Kathryn; Sedegah, Martha; Doolan, Denise L.; Limbach, Keith; Patterson, Noelle B.; Spring, Michele; Ockenhouse, Christian F.; Richie, Thomas] Naval Med Res Ctr, Walter Reed Army Inst Res, Silver Spring, MD USA.
[Williams, Francis] Natl Naval Med Ctr, Bethesda, MD USA.
[Bruder, Joseph T.; King, C. R.] GenVec Inc, Gaithersburg, MD USA.
[Soisson, Lorraine; Diggs, Carter] US Agcy Int Dev, Washington, DC 20523 USA.
RI Doolan, Denise/F-1969-2015
NR 0
TC 0
Z9 0
U1 2
U2 4
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 7
BP 3
EP 3
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600008
ER
PT J
AU Thera, MA
Doumbo, OK
Coulibaly, D
Laurens, MB
Kone, AK
Guindo, AB
Diallo, DA
Traore, K
Diarra, I
Niangaly, A
Dolo, A
Daou, M
Sissoko, M
Sissoko, MS
Kouriba, B
Traore, D
Lyke, KE
Takala, SL
Godeaux, O
Diggs, C
Dutta, S
Stewart, VA
House, B
Heppner, DG
Plowe, CV
Cohen, J
Ballou, WR
Thonnard, J
Dubois, MC
Soisson, L
Ware, LA
Lanar, DE
AF Thera, Mahamadou A.
Doumbo, Ogobara K.
Coulibaly, Drissa
Laurens, Matthew B.
Kone, Abdoulaye K.
Guindo, Ando B.
Diallo, Dapa A.
Traore, Karim
Diarra, Issa
Niangaly, Amadou
Dolo, Amagana
Daou, Modibo
Sissoko, Mady
Sissoko, Mahamadou S.
Kouriba, Bourema
Traore, Drissa
Lyke, Kirsten E.
Takala, Shannon L.
Godeaux, Olivier
Diggs, Carter
Dutta, Sheetij
Stewart, V. Ann
House, Brent
Heppner, D. Gray
Plowe, Christopher V.
Cohen, Joe
Ballou, W. Ripley
Thonnard, Joelle
Dubois, Marie-Claude
Soisson, Lorraine
Ware, Lisa A.
Lanar, David E.
TI RANDOMIZED, CONTROLLED, PHASE 2B CLINICAL TRIAL TO EVALUATE THE SAFETY,
IMMUNOGENICITY AND EFFICACY OF WALTER REED ARMY INSTITUTE OF RESEARCH'S
AMA-1 MALARIA VACCINE (FMP2.1) ADJUVANTED IN GSK BIOLOGICALS' AS02 VS.
RABIES VACCINE IN 1-6 YEAR OLD CHILDREN IN BANDIAGARA, MALI
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Thera, Mahamadou A.; Doumbo, Ogobara K.; Coulibaly, Drissa; Kone, Abdoulaye K.; Guindo, Ando B.; Diallo, Dapa A.; Traore, Karim; Diarra, Issa; Niangaly, Amadou; Dolo, Amagana; Daou, Modibo; Sissoko, Mady; Sissoko, Mahamadou S.; Kouriba, Bourema; Traore, Drissa] Univ Bamako, Fac Med, Bamako, Mali.
[Laurens, Matthew B.; Lyke, Kirsten E.; Takala, Shannon L.; Plowe, Christopher V.] Univ Maryland, Sch Med, Baltimore, MD 21201 USA.
[Godeaux, Olivier; Cohen, Joe; Ballou, W. Ripley; Dubois, Marie-Claude] GlaxoSmithKline Biol, Rixensart, Belgium.
[Diggs, Carter] US Agcy Int Dev, Washington, DC 20523 USA.
[Dutta, Sheetij; Stewart, V. Ann; House, Brent; Heppner, D. Gray; Ware, Lisa A.; Lanar, David E.] Walter Reed Army Inst Res, Silver Spring, MD USA.
RI Lanar, David/B-3560-2011
NR 0
TC 0
Z9 0
U1 0
U2 3
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 25
BP 8
EP 8
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600026
ER
PT J
AU Parker, M
Fine, D
Glass, P
Terpening, S
Mallory, R
Helbers, S
AF Parker, Michael
Fine, Donald
Glass, Pamela
Terpening, Sara
Mallory, Rayburn
Helbers, Sarah
TI PHASE I CLINICAL TRIAL OF V3526, VIROLOGICAL AND SEROLOGICAL ANALYSES
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Parker, Michael; Glass, Pamela; Mallory, Rayburn] USA, Med Res Inst Infect Dis, Frederick, MD USA.
[Fine, Donald; Terpening, Sara] Dymport Vaccine Co LLC, Frederick, MD USA.
[Helbers, Sarah] Commonwealth Biotechnol Inc, Richmond, VA USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 62
BP 19
EP 19
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600063
ER
PT J
AU Campagna, JD
Nemmers, ST
AF Campagna, John D.
Nemmers, Suzie T.
TI OPHTHALMOMYIASIS BY CALLIPHORIDAE LARVAE IN A 16-YEAR-OLD FEMALE FROM
HAWAII
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Campagna, John D.; Nemmers, Suzie T.] Tripler Army Med Ctr, Honolulu, HI 96859 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 69
BP 21
EP 21
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600070
ER
PT J
AU Hartzell, JD
Gleeson, T
Ockenhouse, C
Wortmann, G
AF Hartzell, Joshua D.
Gleeson, Todd
Ockenhouse, Chris
Wortmann, Glenn
TI Q FEVER COMPLICATED BY OGILVIE'S SYNDROME IN A US SOLDIER
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Hartzell, Joshua D.; Wortmann, Glenn] Walter Reed Army Med Ctr, Washington, DC 20307 USA.
[Gleeson, Todd] Natl Naval Med Ctr, Bethesda, MD USA.
[Ockenhouse, Chris] Walter Reed Army Inst Res, Silver Spring, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 95
BP 28
EP 28
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600096
ER
PT J
AU Thomas, S
Nisalak, A
Libraty, D
Sahasakmontri, N
Kalayanarooj, S
Vaughn, D
Putnak, R
Endy, T
AF Thomas, Stephen
Nisalak, Ananda
Libraty, Daniel
Sahasakmontri, Nongnard
Kalayanarooj, Siripen
Vaughn, David
Putnak, Robert
Endy, Timothy
TI PERFORMANCE OF THE DENGUE PLAQUE REDUCTION NEUTRALIZATION TEST (PRNT) IN
PRIMARY AND SECONDARY DENGUE VIRUS (DENV) INFECTIONS ACROSS A SPECTRUM
OF TEST CONDITIONS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Thomas, Stephen; Nisalak, Ananda] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Libraty, Daniel] Univ Massachusetts, Sch Med, Worcester, MA USA.
[Sahasakmontri, Nongnard; Kalayanarooj, Siripen] Queen Sirikit Natl Inst Child Hlth, Bangkok, Thailand.
[Vaughn, David] GlaxoSmithKline Biol, King Of Prussia, PA USA.
[Putnak, Robert] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Endy, Timothy] SUNY Upstate Med Univ, Syracuse, NY USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 120
BP 36
EP 36
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600121
ER
PT J
AU Jarman, RG
Klungthong, C
Holmes, EC
Chinnawirotpisan, P
Rodpradit, P
Pimgate, C
Scott, TW
Rothman, AL
Yoon, IK
Gibbons, RV
AF Jarman, Richard G.
Klungthong, Chonticha
Holmes, Edward C.
Chinnawirotpisan, Piyawan
Rodpradit, Prinyada
Pimgate, Chusak
Scott, Thomas W.
Rothman, Alan L.
Yoon, In-Kyu
Gibbons, Robert V.
TI GENETIC ANALYSIS OF DENGUE VIRUSES COLLECTED FROM MOSQUITOES AND HUMANS
DURING DENGUE CLUSTER INVESTIGATIONS IN THAILAND
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Jarman, Richard G.; Klungthong, Chonticha; Chinnawirotpisan, Piyawan; Rodpradit, Prinyada; Pimgate, Chusak; Yoon, In-Kyu; Gibbons, Robert V.] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Holmes, Edward C.] Penn State Univ, University Pk, PA 16802 USA.
[Scott, Thomas W.] Univ Calif Davis, Davis, CA 95616 USA.
[Rothman, Alan L.] Univ Massachusetts, Sch Med, Worcester, MA USA.
NR 0
TC 0
Z9 0
U1 0
U2 2
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 125
BP 37
EP 37
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600126
ER
PT J
AU Vithessonthi, K
Pancharoen, C
Thisyakorn, C
Nisalak, A
Thisyakorn, U
AF Vithessonthi, Kanyalak
Pancharoen, Chitsanu
Thisyakorn, Chule
Nisalak, Ananda
Thisyakorn, Usa
TI SEROEPIDEMIOLOGY OF DENGUE VIRUS INFECTION IN HIV-INFECTED CHILDREN IN
COMPARISON TO HEALTHY CHILDREN
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Vithessonthi, Kanyalak; Pancharoen, Chitsanu; Thisyakorn, Chule; Thisyakorn, Usa] King Chulalongkorn Mem Hosp, Bangkok, Thailand.
[Nisalak, Ananda] US Army Med Component, Armed Forces Res Inst Med Sci, Bangkok, Thailand.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 147
BP 44
EP 44
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600148
ER
PT J
AU Milhous, WK
Gerena, L
O'Neil, M
Ahumada, A
Hoffman, S
AF Milhous, Wilbur K.
Gerena, Lucia
O'Neil, Mike
Ahumada, Adriana
Hoffman, Stephen
TI CHEMOTHERAPEUTIC EVALUATION OF WHOLE CELL MALARIA VACCINE CANDIDATES
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Milhous, Wilbur K.] Univ S Florida, Tampa, FL USA.
[Gerena, Lucia; O'Neil, Mike] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Ahumada, Adriana] Sanaria Inc, Rockville, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 176
BP 52
EP 52
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600177
ER
PT J
AU Macareo, L
Li, QG
Smith, B
Polhemus, M
Miller, S
AF Macareo, Louis
Li, Qigui
Smith, Bryan
Polhemus, Mark
Miller, Scott
TI AREA UNDER THE EFFICACY CURVE ANALYSIS OF INTRAVENOUS ARTESUNATE IN
TREATMENT OF SEVERE MALARIA
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Macareo, Louis; Li, Qigui; Miller, Scott] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Smith, Bryan] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Polhemus, Mark] USA, Med Res Unit, Kisumu, Kenya.
NR 0
TC 0
Z9 0
U1 2
U2 3
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 178
BP 53
EP 53
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600179
ER
PT J
AU Li, QG
Cantilena, LR
Leary, KJ
Saviolakis, GA
Miller, RS
Melendez, V
Weina, PJ
AF Li, Qigui
Cantilena, Louis R.
Leary, Kevin J.
Saviolakis, George A.
Miller, R. Scott
Melendez, Victor
Weina, Peter J.
TI PHARMACOKINETIC EVALUATION OF ARTESUNATE FOLLOWING SINGLE INTRAVENOUS
INJECTION OF 0.5, 1, 2, 4, AND 8 MG/KG IN NORMAL, HEALTHY VOLUNTEERS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Li, Qigui; Miller, R. Scott; Melendez, Victor; Weina, Peter J.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Cantilena, Louis R.; Leary, Kevin J.; Saviolakis, George A.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
SU S
MA 182
BP 54
EP 54
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600183
ER
PT J
AU Li, QG
Weina, PJ
AF Li, Qigui
Weina, Peter J.
TI COMPARTMENTAL MODEL-DEPENDENT ANALYSIS OF PHARMACOKINETIC DATA OF
ARTESUNATE FOLLOWING SHORT-TERM INFUSION IN HEALTH VOLUNTEERS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Li, Qigui; Weina, Peter J.] Walter Reed Army Inst Res, Silver Spring, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
SU S
MA 183
BP 54
EP 54
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600184
ER
PT J
AU Zhang, J
Xie, LH
Zeng, Q
Peacock, E
Li, QG
O'Neil, MT
AF Zhang, Jing
Xie, Lisa H.
Zeng, Qiang
Peacock, Erin
Li, Qigui
O'Neil, Michael T.
TI EFFECTS OF PLASMODIUM BERGHEI AND P. YOELII SPOROZOITE NUMBER ON IN VIVO
INFECTION RATES AND TIME TO PATENCY IN C57BL/6 MICE
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Zhang, Jing; Xie, Lisa H.; Zeng, Qiang; Peacock, Erin; Li, Qigui; O'Neil, Michael T.] Walter Reed Army Inst Res, Silver Spring, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 184
BP 54
EP 55
PG 2
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600185
ER
PT J
AU Gu, YC
Li, QG
Meledez, V
Weina, PJ
AF Gu, Yuanchao C.
Li, Qigui
Meledez, Victor
Weina, Peter J.
TI COMPARISON OF HPLC WITH ELECTROCHEMICAL DETECTION AND LC-MS/MS FOR THE
SEPARATION AND VALIDATION OF ARTESUNATE AND DIHYDROARTEMISININ IN ANIMAL
AND HUMAN PLASMA
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Gu, Yuanchao C.; Li, Qigui; Meledez, Victor; Weina, Peter J.] Walter Reed Army Inst Res, Silver Spring, MD USA.
RI Weina, Peter/A-2120-2011
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 185
BP 55
EP 55
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600186
ER
PT J
AU Myint, HY
Ohrt, C
Sampath, A
Walker, L
White, N
Magill, A
AF Myint, Hla Y.
Ohrt, Colin
Sampath, Aruna
Walker, Larry
White, Nick
Magill, Alan
TI CLINICAL SAFETY AND DRUG INTERACTIONS WITH 8-AMINOQUINOLINES
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Myint, Hla Y.; Ohrt, Colin; Magill, Alan] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Sampath, Aruna; Walker, Larry] Univ Mississippi, University, MS 38677 USA.
[White, Nick] Mahidol Univ, Fac Trop Med, Mahidol Oxford Res Unit, Bangkok, Thailand.
RI White, Nicholas/I-4629-2012
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 188
BP 55
EP 56
PG 2
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600189
ER
PT J
AU Xie, LH
Li, QG
Zhang, J
Weina, PJ
AF Xie, Lisa H.
Li, Qigui
Zhang, Jing
Weina, Peter J.
TI TISSUE DISTRIBUTION, METABOLIC PROFILES AND PROTEIN BINDING OF (C-14)
DIHYDROARTEMISININ FOLLOWING SINGLE INTRAVENOUS ADMINISTRATION IN RATS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Xie, Lisa H.; Li, Qigui; Zhang, Jing; Weina, Peter J.] Walter Reed Army Inst Res, Silver Spring, MD USA.
RI Weina, Peter/A-2120-2011
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
SU S
MA 186
BP 55
EP 55
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600187
ER
PT J
AU Rothstein, Y
Myer, J
Dow, G
Wasson, P
Walker, L
Magill, A
Ohrt, CK
AF Rothstein, Yarrow
Myer, James
Dow, Geoffrey
Wasson, Peggy
Walker, Larry
Magill, Alan
Ohrt, Colin K.
TI EVIDENCE OF HEMOLYTIC ANEMIA IN TAFENOQUINE AND PRIMAQUINE ANIMAL
STUDIES
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Rothstein, Yarrow; Dow, Geoffrey; Wasson, Peggy; Walker, Larry; Magill, Alan; Ohrt, Colin K.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Myer, James] GlaxoSmithKline Inc, Res Triangle Pk, NC USA.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 189
BP 56
EP 56
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600190
ER
PT J
AU Zhu, GD
Gao, Q
Zhou, HY
Li, JL
Lu, F
Liu, YB
Jetsumon, S
AF Zhu, Guoding
Gao, Qi
Zhou, Huayun
Li, Julin
Lu, Feng
Liu, Yaobao
Jetsumon, Sattabongkot
TI SUSCEPTIBILITY OF PLASMODIUM VIVAX TO ANOPHELES ANTHROPOPHAGUS FROM
DIFFERENT AREAS IN CHINA
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Zhu, Guoding; Gao, Qi; Zhou, Huayun; Li, Julin; Lu, Feng; Liu, Yaobao] Jiangsu Inst Parasit Dis, Wuxi, Peoples R China.
[Jetsumon, Sattabongkot] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 245
BP 72
EP 72
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600246
ER
PT J
AU Turell, MJ
Wilson, WC
Bennett, K
AF Turell, Michael J.
Wilson, William C.
Bennett, Kristine
TI POTENTIAL FOR NORTH AMERICAN MOSQUITOES TO TRANSMIT RIFT VALLEY FEVER
VIRUS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Turell, Michael J.] USA, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA.
[Wilson, William C.; Bennett, Kristine] ARS, USDA, Arthropod Borne Anim Dis Res Lab, Laramie, WY USA.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 257
BP 75
EP 75
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600258
ER
PT J
AU Jeamwattanalert, P
Ruang-Areerate, T
Sunyakumthorn, P
Mason, CJ
Gaywee, J
AF Jeamwattanalert, Pimmada
Ruang-areerate, Toon
Sunyakumthorn, Piyanate
Mason, Carl J.
Gaywee, Jariyanart
TI GENETIC DIVERSITY OF ORIENTIA TSUTSUGAMUSHI FROM FEBRILE PATIENT IN
UPPER REGIONS OF THAILAND DURING 2004-2007
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Jeamwattanalert, Pimmada; Ruang-areerate, Toon; Sunyakumthorn, Piyanate; Mason, Carl J.; Gaywee, Jariyanart] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 267
BP 78
EP 78
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600268
ER
PT J
AU Murray, CK
Pimentel, G
Parker, T
Beckius, ML
Samir, A
Rhman, BA
Mende, K
Galloway, RL
Hospenthal, DR
AF Murray, Clinton K.
Pimentel, Guillermo
Parker, Tina
Beckius, Miriam L.
Samir, Ahmed
Rhman, Bassern Abdel
Mende, Katrin
Galloway, Renee L.
Hospenthal, Duane R.
TI ANTIMICROBIAL SUSCEPTIBILITIES OF CLINICAL HUMAN ISOLATES OF LEPTOSPIRA
FROM EGYPT
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Murray, Clinton K.; Beckius, Miriam L.; Hospenthal, Duane R.] Brooke Army Med Ctr, Ft Sam Houston, TX 78234 USA.
[Pimentel, Guillermo; Rhman, Bassern Abdel] US NAMRU3, Cairo, Egypt.
[Parker, Tina] NIH, Bethesda, MD 20892 USA.
[Samir, Ahmed] Cairo Univ, Cairo, Egypt.
[Mende, Katrin] Infect Dis Clin Res Program, Ft Sam Houston, TX USA.
[Galloway, Renee L.] Ctr Dis Control & Prevent, Atlanta, GA USA.
NR 0
TC 3
Z9 3
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 266
BP 78
EP 78
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600267
ER
PT J
AU Hinkle, MK
Green, JA
Martin, GJ
Kochel, TJ
Hall, ER
Villaran, M
Garcia, J
Scott, P
Bautista, CT
Sateren, WB
Gray, M
Murray, CK
Hospenthal, DR
Maves, RC
AF Hinkle, Mary K.
Green, Justin A.
Martin, Gregory J.
Kochel, Tacleusz J.
Hall, Eric R.
Villaran, Manuel
Garcia, Josefina
Scott, Paul
Bautista, Christian T.
Sateren, Warren B.
Gray, Michael
Murray, Clinton K.
Hospenthal, Duane R.
Maves, Ryan C.
TI SEROSURVEY OF LEPTOSPIROSIS IN PERUVIAN MILITARY PERSONNEL DEPLOYED TO
HAITI
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Hinkle, Mary K.; Murray, Clinton K.; Hospenthal, Duane R.] Brooke Army Med Ctr, San Antonio, TX USA.
[Green, Justin A.; Kochel, Tacleusz J.; Hall, Eric R.; Villaran, Manuel; Garcia, Josefina; Maves, Ryan C.] Naval Med Res Ctr Detachment, Lima, Peru.
[Martin, Gregory J.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
[Scott, Paul; Bautista, Christian T.; Sateren, Warren B.] Walter Reed Army Inst Res, Rockville, MD USA.
RI Bautista, Christian/B-2812-2011
NR 0
TC 2
Z9 2
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 269
BP 79
EP 79
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600270
ER
PT J
AU Woodring, JV
Srijan, A
Mason, C
AF Woodring, Joseph V.
Srijan, Apichai
Mason, Carl
TI PREVALENCE OF VIBRIO, AEROMONAS AND SALMONELLA SPECIES IN VARIOUS
SEAFOODS FROM SUPERMARKETS AND FRESH MARKETS IN BANGKOK, THAILAND
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Woodring, Joseph V.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Srijan, Apichai; Mason, Carl] USA, Med Component, Armed Forces Res Inst Med Sci, Bangkok, Thailand.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 270
BP 79
EP 79
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600271
ER
PT J
AU Robertson, JL
Becker, SJ
Yu, X
Hawley, JA
Griffith, ME
Bekius, ML
Hospenthal, DR
Mende, K
Murray, CK
AF Robertson, Jainelle L.
Becker, Sara J.
Yu, Xin
Hawley, Joshua A.
Griffith, Matthew E.
Bekius, Miriam L.
Hospenthal, Duane R.
Mende, Katrin
Murray, Clinton K.
TI DETECTION OF LEPTOSPIRAL DNA FROM INOCULATED BLOOD AND URINE SAMPLES
USING FIVE PCR PRIMERS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Robertson, Jainelle L.; Becker, Sara J.; Hawley, Joshua A.; Griffith, Matthew E.; Hospenthal, Duane R.; Murray, Clinton K.] Brooke Army Med Ctr, San Antonio, TX USA.
[Yu, Xin; Bekius, Miriam L.; Mende, Katrin] Infect Dis Clin Res Program, San Antonio, TX USA.
NR 0
TC 1
Z9 1
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 275
BP 80
EP 80
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600276
ER
PT J
AU Schoepp, RJ
McKinney, MD
Moon, SJ
Kulesh, DA
Larsen, T
AF Schoepp, Randal J.
McKinney, Michelle D.
Moon, Steven J.
Kulesh, David A.
Larsen, Thomas
TI DETECTION OF VIRAL RNA FROM PARAFFIN-EMBEDDED TISSUES AFTER PROLONGED
FORMALIN FIXATION
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Schoepp, Randal J.; Moon, Steven J.; Kulesh, David A.; Larsen, Thomas] USA, Med Res Inst Infect Dis, Frederick, MD USA.
[McKinney, Michelle D.] Geocenters Inc, Frederick, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 314
BP 92
EP 92
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600314
ER
PT J
AU Dent, AE
Bergmann-Leitner, E
Wilson, D
Tisch, D
Kimmel, R
Vulule, J
Sumba, P
Beeson, J
Angov, E
Moormann, A
Kazura, J
AF Dent, Arlene E.
Bergmann-Leitner, Elke
Wilson, Danny
Tisch, Daniel
Kimmel, Rhonda
Vulule, John
Sumba, Peter
Beeson, James
Angov, Evelina
Moormann, Ann
Kazura, James
TI IMMUNITY TO PLASMODIUM FALCIPARUM MEASURED BY GROWTH INHIBITION ASSAY
DECREASES WITH AGE AND IS ASSOCIATED WITH DELAYED TIME TO BLOOD STAGE
INFECTION IN NATURALLY EXPOSED PERSONS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Dent, Arlene E.; Tisch, Daniel; Moormann, Ann; Kazura, James] Case Western Reserved Univ, Cleveland, OH USA.
[Bergmann-Leitner, Elke; Angov, Evelina] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Wilson, Danny; Beeson, James] Royal Melbourne Hosp, Walter & Eliza Hall Inst Med Res, Parkville, Vic 3050, Australia.
[Kimmel, Rhonda] Case Western Reserve Univ, Cleveland, OH 44106 USA.
[Vulule, John; Sumba, Peter] Kenya Govt Med Res Ctr, Kisumu, Kenya.
RI Bergmann-Leitner, Elke/B-3548-2011
OI Bergmann-Leitner, Elke/0000-0002-8571-8956
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 326
BP 95
EP 96
PG 2
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600326
ER
PT J
AU Kayatani, AK
Fukuda, MM
Leke, RG
Taylor, DW
AF Kayatani, Alexander K.
Fukuda, Mark M.
Leke, Rose G.
Taylor, Diane W.
TI COMPARISON OF SEROLOGICAL PROFILES AND ANTIBODY AVIDITIES TO EIGHT MAJOR
CANDIDATE VACCINE ANTIGENS IN THAI AND CAMEROON ADULTS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Kayatani, Alexander K.; Taylor, Diane W.] Univ Hawaii, Honolulu, HI 96822 USA.
[Fukuda, Mark M.] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Leke, Rose G.] Univ Yaounde 1, Yaounde, Cameroon.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 327
BP 96
EP 96
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600327
ER
PT J
AU Cummings, DA
Iamsirithaworn, S
Lessler, J
Prasanthong, R
Jarman, RG
Burke, DS
Gibbons, RV
AF Cummings, Derek A.
Iamsirithaworn, Sopon
Lessler, Justin
Prasanthong, Rungnapa
Jarman, Richard G.
Burke, Donald S.
Gibbons, Robert V.
TI DENGUE AND THE DEMOGRAPHIC TRANSITION
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Cummings, Derek A.; Lessler, Justin] Johns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA.
[Iamsirithaworn, Sopon; Prasanthong, Rungnapa] Minist Publ Hlth, Nonthaburi, Thailand.
[Jarman, Richard G.; Gibbons, Robert V.] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Burke, Donald S.] Univ Pittsburgh, Grad Sch Publ Hlth, Pittsburgh, PA USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 385
BP 113
EP 114
PG 2
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600385
ER
PT J
AU Libraty, DH
Capeding, RM
Acosta, L
Tallo, V
Mercado, E
Bautista, A
Jarman, RG
Yoon, IK
Gibbons, RV
Brion, JD
AF Libraty, Daniel H.
Capeding, Rosario M.
Acosta, Luz
Tallo, Veronica
Mercado, Edel
Bautista, Analisa
Jarman, Richard G.
Yoon, In-Kyu
Gibbons, Robert V.
Brion, Job D.
TI A PROSPECTIVE STUDY OF PRIMARY DENGUE VIRUS INFECTIONS DURING INFANCY:
PRELIMINARY FINDINGS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Libraty, Daniel H.] Univ Massachusetts, Sch Med, Worcester, MA USA.
[Capeding, Rosario M.; Acosta, Luz; Tallo, Veronica; Mercado, Edel; Bautista, Analisa] Res Inst Trop Med, Manila, Philippines.
[Jarman, Richard G.; Yoon, In-Kyu; Gibbons, Robert V.] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Brion, Job D.] San Pablo City Hlth Off, San Pablo, Philippines.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 389
BP 115
EP 115
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600389
ER
PT J
AU Kosoy, MY
Bai, Y
Lerdthusnee, K
Richardson, JH
Boonmar, S
Peruski, LF
Suttirattana, S
Maloney, SA
AF Kosoy, Michael Y.
Bai, Ying
Lerdthusnee, Kriangkrai
Richardson, Jason H.
Boonmar, Sumalee
Peruski, Leonard F.
Suttirattana, Saithip
Maloney, Susan A.
TI PHYLOGENETIC RELATIONS BETWEEN BARTONELLA STRAINS IDENTIFIED IN ANIMALS
AND HUMANS FROM THAILAND
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Kosoy, Michael Y.; Bai, Ying] Ctr Dis Control & Prevent, Div Vector Borne Infect Dis, Ft Collins, CO USA.
[Lerdthusnee, Kriangkrai; Richardson, Jason H.] Armed Forces Res Inst Med Sci, Dept Entomol, Bangkok 10400, Thailand.
[Boonmar, Sumalee] Kasetsart Univ, Fac Med Vet, Bangkok, Thailand.
[Peruski, Leonard F.; Suttirattana, Saithip; Maloney, Susan A.] Thailand MOPH US CDC Collaborat, Int Emerging Infect Program, Nonthaburi, Thailand.
RI Richardson, Jason/A-9441-2011
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 416
BP 123
EP 123
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600416
ER
PT J
AU Deye, G
Remich, S
Ntoburi, S
Cook, E
Apollo, D
House, B
Ohrt, C
AF Deye, Gregory
Remich, Shon
Ntoburi, Stephen
Cook, Earnest
Apollo, Duncan
House, Brent
Ohrt, Colin
TI THE USE OF ANTI-MSP1 ELISA TO IDENTIFY NON-IMMUNE INDIVIDUALS FOR
INCLUSION IN MALARIA PROPHYLAXIS TRIALS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Deye, Gregory; House, Brent; Ohrt, Colin] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Remich, Shon] Walter Reed Army Med Ctr, Silver Spring, MD USA.
[Ntoburi, Stephen] Wellcome Trust Res Programme, Kenya Med Res Inst, Nairobi, Kenya.
[Cook, Earnest; Apollo, Duncan] Kenya Govt Med Res Ctr, Clin Res Ctr, Malaria Diagnost Ctr Excellence, Kisumu, Kenya.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 458
BP 135
EP 135
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600457
ER
PT J
AU Sharlow, ER
Grieser, H
Yellow-Duke, A
Leimgruber, S
Close, D
Barrett, R
Johnson, J
O'Neil, M
Magill, A
Lazo, JS
AF Sharlow, Elizabeth R.
Grieser, Heather
Yellow-Duke, Archibong
Leimgruber, Stephanie
Close, David
Barrett, Rebecca
Johnson, Jacob
O'Neil, Michael
Magill, Alan
Lazo, John S.
TI DEVELOPMENT AND IMPLEMENTATION OF A LIFE CYCLE-DEPENDENT, PHENOTYPIC
HIGH THROUGHPUT LEISHMANIA MAJOR PROMASTIGOTE DRUG SUSCEPTIBILITY ASSAYS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Sharlow, Elizabeth R.; Lazo, John S.] Univ Pittsburgh, Drug Discovery Inst, Dept Pharmacol & Chem Biol, Pittsburgh, PA USA.
[Johnson, Jacob; O'Neil, Michael; Magill, Alan] Walter Reed Army Inst Res, Silver Spring, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 472
BP 139
EP 139
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600471
ER
PT J
AU Potts, JA
Kalayanarooj, S
Nimmannitya, S
Srikiatkhachorn, A
Nisalak, A
Vaughn, DW
Endys, TP
Libraty, DH
Green, S
Rothman, AL
AF Potts, James A.
Kalayanarooj, Siripen
Nimmannitya, Suchitra
Srikiatkhachorn, Anon
Nisalak, Ananda
Vaughn, David W.
Endys, Timothy P.
Libraty, Daniel H.
Green, Sharone
Rothman, Alan L.
TI CLASSIFICATION AND REGRESSION TREE (CART) ANALYSIS USING CLINICAL
LABORATORY VARIABLES KNOWN TO BE ASSOCIATED WITH DENGUE TO ESTABLISH
EARLY DISEASE CLASSIFICATION
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Potts, James A.; Srikiatkhachorn, Anon; Libraty, Daniel H.; Green, Sharone; Rothman, Alan L.] Univ Massachusetts, Sch Med, Worcester, MA USA.
[Kalayanarooj, Siripen; Nimmannitya, Suchitra] Queen Sirikit Natl Inst Child Hlth, Bangkok, Thailand.
[Nisalak, Ananda] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Vaughn, David W.] USA, Med Res & Mat Command, Ft Detrick, MD USA.
[Endys, Timothy P.] Upstate Med Univ, NYU, Syracuse, NY USA.
NR 0
TC 0
Z9 0
U1 0
U2 2
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 484
BP 143
EP 143
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600483
ER
PT J
AU Haraoui, LP
Koles, N
Howard, RS
Wortmann, GW
Polhemus, M
Aronson, NE
AF Haraoui, Louis-Patrick
Koles, Nancy
Howard, Robin S.
Wortmann, Glenn W.
Polhemus, Mark
Aronson, Naomi E.
TI SERUM NITRIC OXIDE (NO) LEVELS IN CUTANEOUS LEISHMANIASIS (CL):
CORRELATIONS WITH TREATMENT OUTCOME AND THE ADVERSE EVENT OF
PANCREATITIS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Haraoui, Louis-Patrick] McGill Univ, Dept Med, Internal Med Residency Training Program, Montreal, PQ, Canada.
[Koles, Nancy; Aronson, Naomi E.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
[Howard, Robin S.; Wortmann, Glenn W.; Polhemus, Mark] Walter Reed Army Med Ctr, Washington, DC 20307 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 544
BP 160
EP 160
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600543
ER
PT J
AU Sampath, A
Tekwani, B
Rochford, R
Ray, P
Friedman, J
McMillan, D
Bhonsle, J
Rothstein, Y
Magill, A
Walker, L
Ohrt, C
AF Sampath, Aruna
Tekwani, Babu
Rochford, Rosemary
Ray, Prabhati
Friedman, Jeffery
McMillan, David
Bhonsle, Jayendra
Rothstein, Yarrow
Magill, Alan
Walker, Larry
Ohrt, Colin
TI IDENTIFICATION OF MODELS TO PREDICT A NON-HEMOLYTIC 8-AMINOQUINOLINE
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Sampath, Aruna; Tekwani, Babu; Walker, Larry] Univ Mississippi, University, MS 38677 USA.
[Rochford, Rosemary] SUNY Upstate Med Univ, Syracuse, NY USA.
[Ray, Prabhati; Bhonsle, Jayendra; Rothstein, Yarrow; Magill, Alan; Ohrt, Colin] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Friedman, Jeffery] Scripps Res Inst, La Jolla, CA USA.
[McMillan, David] Univ Nebraska Med Ctr, Omaha, NE USA.
RI Bhonsle, Jayendra/A-9139-2011
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 581
BP 171
EP 172
PG 2
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600580
ER
PT J
AU Gutteridge, CE
Major, JW
Nin, DA
Bhattacharjee, AK
Gerena, L
AF Gutteridge, Clare E.
Major, Joshua W.
Nin, Daniel A.
Bhattacharjee, Apurba K.
Gerena, Lucia
TI ANTIMALARIAL ACTIVITY OF ARYL-SUBSTITUTED 2-ETHOXYACETAMIDES
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Gutteridge, Clare E.; Major, Joshua W.; Nin, Daniel A.] USN Acad, Annapolis, MD USA.
[Bhattacharjee, Apurba K.; Gerena, Lucia] Walter Reed Army Inst Res, Silver Spring, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 583
BP 172
EP 172
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600582
ER
PT J
AU Saunders, D
Kozar, M
Victor, M
Li, QQ
Teja-Isavadharm, P
Montip, G
O'Neill, M
Ohrt, C
Magill, A
Lin, AJ
AF Saunders, David
Kozar, Michael
Victor, Melendez
Li, Qiqui
Teja-Isavadharm, Paktiya
Montip, Gettayacamin
O'Neill, Michael
Ohrt, Colin
Magill, Alan
Lin, Ai J.
TI PHARMACOKINETIC-PHARMACODYNAMIC RELATIONSHIPS OF IMIDAZOLIDINEDIONE
DERIVATIVES
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Saunders, David; Kozar, Michael; Victor, Melendez; Li, Qiqui; Teja-Isavadharm, Paktiya; Montip, Gettayacamin; O'Neill, Michael; Ohrt, Colin; Magill, Alan; Lin, Ai J.] Walter Reed Army Inst Res, Silver Spring, MD USA.
RI Kozar, Michael/A-9155-2011
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 589
BP 174
EP 174
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644600588
ER
PT J
AU Bergmann-Leitner, ES
Mease, RM
Laquer, KM
Duncan, EH
Savranskaya, T
Williams, JL
Ockenhouse, CF
Angov, E
AF Bergmann-Leitner, Elke S.
Mease, Ryan M.
Laquer, Kari M.
Duncan, Elizabeth H.
Savranskaya, Tatiana
Williams, Jack L.
Ockenhouse, Christian F.
Angov, Evelina
TI EVALUATION OF HUMORAL AND CELLULAR RESPONSES INDUCED BY PLASMODIUM
BERGHEI CELTOS ADMINISTERED BY RECOMBINANT PROTEIN AND GENE-GUN DELIVERY
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Bergmann-Leitner, Elke S.; Mease, Ryan M.; Laquer, Kari M.; Duncan, Elizabeth H.; Savranskaya, Tatiana; Williams, Jack L.; Ockenhouse, Christian F.; Angov, Evelina] Walter Reed Army Inst Res, Silver Spring, MD USA.
RI Bergmann-Leitner, Elke/B-3548-2011
OI Bergmann-Leitner, Elke/0000-0002-8571-8956
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 643
BP 190
EP 190
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601008
ER
PT J
AU McGrath, S
Cummings, J
Kortepeter, M
Nielsen, R
Tierney, E
Ware, L
Ofori-Anyinam, O
Dutta, S
Lanar, D
Sedegah, M
Kester, K
Malkin, E
Diggs, C
Soisson, L
Dubois, MC
Ballou, R
Cohen, J
Krzych, U
Ockenhouse, C
Heppner, G
Spring, M
AF McGrath, Shannon
Cummings, James
Kortepeter, Mark
Nielsen, Robin
Tierney, Ev
Ware, Lisa
Ofori-Anyinam, Opokua
Dutta, Sheetij
Lanar, David
Sedegah, Martha
Kester, Kent
Malkin, Elissa
Diggs, Carter
Soisson, Lorraine
Dubois, Marie-Claude
Ballou, Ripley
Cohen, Joe
Krzych, Urszula
Ockenhouse, Chris
Heppner, Gray
Spring, Michele
TI MULTI-FUNCTIONAL T-CELL RESPONSES INDUCED BY THE AS01 OR AS02 ADJUVANTED
MALARIA VACCINE CANDIDATE APICAL MEMBRANE ANTIGEN-1 (AMA-1) ADMINISTERED
TO MALARIA-NAIVE ADULTS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [McGrath, Shannon; Cummings, James; Nielsen, Robin; Ware, Lisa; Dutta, Sheetij; Lanar, David; Sedegah, Martha; Krzych, Urszula; Ockenhouse, Chris; Heppner, Gray; Spring, Michele] US Mil Malaria Vaccine Program, Silver Spring, MD USA.
[Kortepeter, Mark] USA, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA.
[Tierney, Ev; Malkin, Elissa] PATH Malaria Vaccine Initiat, Bethesda, MD USA.
[Ofori-Anyinam, Opokua; Dubois, Marie-Claude; Cohen, Joe] GlaxoSmithKline Biol, Rixensart, Belgium.
[Kester, Kent] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Diggs, Carter; Soisson, Lorraine] US Agcy Int Dev, Washington, DC 20523 USA.
[Ballou, Ripley] Bill & Melinda Gates Fdn, Seattle, WA USA.
RI Kester, Kent/A-2114-2011; Lanar, David/B-3560-2011
OI Kester, Kent/0000-0002-5056-0802;
NR 0
TC 0
Z9 0
U1 0
U2 2
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 646
BP 191
EP 191
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601011
ER
PT J
AU Spring, M
Bergmann-Leitner, E
James, C
House, B
Krzych, U
Tosh, D
Miller, L
Ware, L
Godeaux, O
Dubois, MC
Lyons, J
Ballou, R
Soisson, L
Diggs, C
Cohen, J
Heppner, G
Ockenhouse, C
Angov, E
AF Spring, Michele
Bergmann-Leitner, Elke
James, Cummings
House, Brent
Krzych, Urszula
Tosh, Donna
Miller, Lori
Ware, Lisa
Godeaux, Olivier
Dubois, Marie-Claude
Lyons, Jeffrey
Ballou, Ripley
Soisson, Lorraine
Diggs, Carter
Cohen, Joe
Heppner, Gray
Ockenhouse, Chris
Angov, Evelina
TI PHASE 1A OPEN-LABEL DOSE ESCALATION STUDY TO EVALUATE THE SAFETY,
REACTOGENICITY, AND IMMUNOGENICITY OF THE CANDIDATE PLASMODIUM
FALCIPARUM MEROZOITE SURFACE PROTEIN-1 (MSP-1(42)) ADMINISTERED
INTRAMUSCULARLY WITH GSK BIOLOGICALS' ADJUVANT SYSTEM AS01B IN HEALTHY
MALARIA-NAIVE ADULTS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Spring, Michele; Bergmann-Leitner, Elke; James, Cummings; House, Brent; Krzych, Urszula; Tosh, Donna; Ware, Lisa; Heppner, Gray; Ockenhouse, Chris; Angov, Evelina] US Mil Malaria Vaccine Program, Silver Spring, MD USA.
[Miller, Lori; Lyons, Jeffrey] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Godeaux, Olivier; Dubois, Marie-Claude; Cohen, Joe] GlaxoSmithKline Biol, Rixensart, Belgium.
[Ballou, Ripley] Bill & Melinda Gates Fdn, Seattle, WA USA.
[Soisson, Lorraine; Diggs, Carter] US Agcy Int Dev, Washington, DC 20523 USA.
RI Bergmann-Leitner, Elke/B-3548-2011
OI Bergmann-Leitner, Elke/0000-0002-8571-8956
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
SU S
MA 647
BP 191
EP 192
PG 2
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601012
ER
PT J
AU Brando, C
Kaba, S
Guo, Q
Steele, M
Mittelholzer, C
Raman, S
Burkhard, P
Lanar, DE
AF Brando, Clara
Kaba, Stephen
Guo, Qin
Steele, Molly
Mittelholzer, Christian
Raman, Senthilkumar
Burkhard, Peter
Lanar, David E.
TI ADJUVANT AND CARRIER EFFECT OF SELF-ASSEMBLING POLYPEPTIDE NANOPARTICLES
(SAPN)
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Brando, Clara; Kaba, Stephen; Guo, Qin; Steele, Molly; Lanar, David E.] Walter Reed Army Inst Res, Div Malaria Vaccine Dev, Silver Spring, MD USA.
[Mittelholzer, Christian; Raman, Senthilkumar] ME Muller Inst Biomech, Basel, Switzerland.
[Burkhard, Peter] Univ Connecticut, Inst Mat Sci, Storrs, CT USA.
RI Kaba, Stephen/B-3555-2011; Lanar, David/B-3560-2011
OI Kaba, Stephen/0000-0003-1509-2975;
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 648
BP 192
EP 192
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601013
ER
PT J
AU Lascano, M
Leistner, C
Wojno, A
Romoser, M
Dohm, D
Trudel, R
Tomc, C
Romoser, WS
AF Lascano, Mauricio
Leistner, Christine
Wojno, Abbey
Romoser, Margaret
Dohm, David
Trudel, Richard
Tomc, Christa
Romoser, William S.
TI CHARACTERIZATION OF WATER-HOLDING CONTAINERS AS MOSQUITO-HABITATS, AND
DENGUE-PREVENTION COMMUNITY EDUCATION IN RURAL ECUADORIAN COMMUNITIES
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Lascano, Mauricio; Romoser, William S.] Ohio Univ, Coll Osteopath Med, Trop Dis Inst, Athens, OH 45701 USA.
[Leistner, Christine] Ohio Univ, Int Dev Studies, Athens, OH 45701 USA.
[Wojno, Abbey; Romoser, Margaret] Ohio Univ, Scripps Coll Commun, Commun Studies, Athens, OH 45701 USA.
[Dohm, David] USA, Med Res Inst Infect Dis, Frederick, MD USA.
[Trudel, Richard] SOPFIM, Soc Protec Forets Insectes & Maladies, Quebec City, PQ, Canada.
[Tomc, Christa] Ohio Univ, Coll Osteopath Med, Athens, OH 45701 USA.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
SU S
MA 695
BP 204
EP 205
PG 2
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601060
ER
PT J
AU Vaughan, JA
Mehus, JO
Bell, JA
Turell, MJ
AF Vaughan, Jefferson A.
Mehus, Joseph O.
Bell, Jeffrey A.
Turell, Michael J.
TI MICROFILARIAL UPTAKE AND PENETRATION OF THE MIDGUT AMONG DIFFERENT
MOSQUITO SPECIES FED SIMULTANEOUSLY ON THE SAME MICROFILAREMIC HOST
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Vaughan, Jefferson A.; Mehus, Joseph O.; Bell, Jeffrey A.] Univ N Dakota, Grand Forks, ND 58201 USA.
[Turell, Michael J.] USA, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 696
BP 205
EP 205
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601061
ER
PT J
AU Brown, TR
Martinez, LJ
Llanos, JK
Lynch, JA
Coldren, RL
AF Brown, Theodore R.
Martinez, Luis J.
Llanos, Joseph K.
Lynch, Julia A.
Coldren, Rodney L.
TI ADENOVIRUS 21 OUTBREAK AT THE COAST GUARD TRAINING CENTER IN CAPE MAY,
NEW JERSEY
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Brown, Theodore R.; Llanos, Joseph K.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
[Martinez, Luis J.; Lynch, Julia A.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Coldren, Rodney L.] USA, Ctr Hlth Promot & Prevent Med, Aberdeen Proving Ground, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 700
BP 206
EP 206
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601065
ER
PT J
AU Coberly, JS
Wojcik, R
Chretien, JP
Lewis, S
AF Coberly, Jacqueline S.
Wojcik, Richard
Chretien, Jean-Paul
Lewis, Sheri
TI SURVEILLANCE OF EMERGING DISEASE IN RESOURCE LIMITED SETTINGS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Coberly, Jacqueline S.; Wojcik, Richard; Lewis, Sheri] Johns Hopkins Univ, Appl Phys Lab, Laurel, MD USA.
[Chretien, Jean-Paul] Walter Reed Army Inst Res, Global Emerging Infect Syst, Silver Spring, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 710
BP 209
EP 209
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601075
ER
PT J
AU Fair, J
Guttieri, M
Branco, L
Geske, J
Khan, H
Schoepp, R
Goba, A
Geisbert, J
Garry, R
Bausch, D
AF Fair, Joseph
Guttieri, Mary
Branco, Luis
Geske, Jon
Khan, Humarr
Schoepp, Randal
Goba, Augustine
Geisbert, Joan
Garry, Robert
Bausch, Daniel
TI DEVELOPMENT AND EVALUATION OF RECOMBINANT ARENAVIRUS PROTEINS FOR USE IN
DIAGNOSTIC, PROPHYLACTIC AND THERAPEUTIC APPLICATIONS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Fair, Joseph; Garry, Robert; Bausch, Daniel] Tulane Univ, New Orleans, LA 70118 USA.
[Guttieri, Mary; Schoepp, Randal] USA, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA.
[Branco, Luis] Biofactura INC, Rockville, MD USA.
[Geske, Jon] Corgenix, Denver, CO USA.
[Khan, Humarr; Goba, Augustine] Kenema Govt Hosp, Kenema, Sierra Leone.
[Geisbert, Joan] Boston Univ, Boston, MA 02215 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 714
BP 210
EP 211
PG 2
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601079
ER
PT J
AU Martin, SS
Parker, MD
Bakken, R
Price, JL
Hart, MK
Fine, DL
AF Martin, Shannon S.
Parker, Michael D.
Bakken, Russell
Price, Jessica L.
Hart, Mary Kate
Fine, Donald L.
TI DETECTION OF FEBRILE RESPONSES IN VENEZUELAN EQUINE ENCEPHALITIS VIRUS
(VEEV) INFECTED MICE
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Martin, Shannon S.; Price, Jessica L.; Hart, Mary Kate; Fine, Donald L.] DynPort Vaccine Co, Frederick, MD USA.
[Parker, Michael D.; Bakken, Russell] USA, Med Res Inst Infect Dis, Frederick, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 720
BP 212
EP 212
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601085
ER
PT J
AU Scott, TW
Carey, JR
Fansiri, T
Richardson, J
AF Scott, Thomas W.
Carey, James R.
Fansiri, Thanyalak
Richardson, Jason
TI A RESIDUAL DEMOGRAPHY METHOD FOR ESTIMATING AGE STRUCTURE OF WILD
MOSQUITO VECTOR POPULATIONS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Scott, Thomas W.; Carey, James R.] Univ Calif Davis, Davis, CA 95616 USA.
[Fansiri, Thanyalak; Richardson, Jason] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
RI Richardson, Jason/A-9441-2011
NR 0
TC 1
Z9 1
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 734
BP 217
EP 217
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601099
ER
PT J
AU Kelly, JX
Smilkstein, M
Melendez, V
Cooper, R
Winter, R
Hinrichs, D
Riscoe, M
AF Kelly, Jane X.
Smilkstein, Martin
Melendez, Victor
Cooper, Roland
Winter, Rolf
Hinrichs, Dave
Riscoe, Mike
TI OPTIMIZATION OF DUAL-FUNCTION ACRIDONE ANTIMALARIALS: IMPROVED EFFICACY
AND SYNERGY WITH PIPERAQUINE
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Kelly, Jane X.; Smilkstein, Martin; Winter, Rolf; Hinrichs, Dave; Riscoe, Mike] Portland VA Med Ctr, Portland, OR USA.
[Melendez, Victor] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Cooper, Roland] Old Dominion Univ, Norfolk, VA USA.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 760
BP 224
EP 224
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601125
ER
PT J
AU Smith, BL
Polhemus, ME
Jongsakul, K
Ogutu, B
Weina, PJ
Miller, RS
AF Smith, Bryan L.
Polhemus, Mark E.
Jongsakul, Krisada
Ogutu, Bernhards
Weina, Peter J.
Miller, R. Scott
TI PHASE II, RANDOMIZED, OPEN-LABEL, DOSE-RANGING STUDY OF GMP INTRAVENOUS
ARTESUNATE FOR OPTIMIZING PARASITE CLEARANCE IN UNCOMPLICATED PLASMODIUM
FALCIPARUM MALARIA
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Smith, Bryan L.; Polhemus, Mark E.; Weina, Peter J.; Miller, R. Scott] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Jongsakul, Krisada] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Ogutu, Bernhards] USA, Med Res Unit Kenya, Nairobi, Kenya.
RI Weina, Peter/A-2120-2011
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 763
BP 225
EP 225
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601128
ER
PT J
AU Gaywee, J
Sirisopana, N
Eamsila, C
Watcharapichat, P
Chuenchitra, T
Vudtakanok, J
Jangyodsuk, V
Boonlikit, S
Srichantrapunt, W
Paonin, S
Pattanarangsan, R
Arthayapan, T
Bodhidatta, L
Jarman, RG
Pavlin, JA
Mason, CJ
AF Gaywee, Jariyanart
Sirisopana, Narongrid
Eamsila, Chirapa
Watcharapichat, Pochaman
Chuenchitra, Thippawan
Vudtakanok, Judpon
Jangyodsuk, Vim
Boonlikit, Smin
Srichantrapunt, Wisuth
Paonin, Surat
Pattanarangsan, Rattaporn
Arthayapan, Thongdang
Bodhidatta, Ladaporn
Jarman, Richard G.
Pavlin, Julie A.
Mason, Carl J.
TI RESPIRATORY DISEASE SURVEILLANCE IN 6 ROYAL THAI ARMY HOSPITALS ALONG
THAI BORDERS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Gaywee, Jariyanart; Sirisopana, Narongrid; Eamsila, Chirapa; Watcharapichat, Pochaman; Chuenchitra, Thippawan; Bodhidatta, Ladaporn; Jarman, Richard G.; Pavlin, Julie A.; Mason, Carl J.] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Vudtakanok, Judpon] Ft Surasi Hosp, Kanchanaburi, Thailand.
[Jangyodsuk, Vim; Boonlikit, Smin] Ft Surasinghanath Hosp, Sa Kaew, Thailand.
[Srichantrapunt, Wisuth] Ft Sunpasitthiprasong Hosp, Ubon Ratchathani, Thailand.
[Paonin, Surat] Ft Mengraimaharat Hosp, Chiangrai, Thailand.
[Pattanarangsan, Rattaporn] Ft Khetudomsak Hosp, Chumphon, Thailand.
[Arthayapan, Thongdang] Ft Ingkayuthaborihan Hosp, Pattani, Thailand.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 801
BP 236
EP 237
PG 2
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601166
ER
PT J
AU Narum, DL
Haynes, JD
Moch, JK
Dutta, S
AF Narum, David L.
Haynes, J. David
Moch, J. Kathleen
Dutta, Sheetij
TI ISOLATION OF INVASIVE LONG LIVED PLASMODIUM FALCIPARUM MEROZOITES BY
CELL SIEVING
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Narum, David L.] Natl Inst Hlth, Rockville, MD USA.
[Haynes, J. David; Moch, J. Kathleen; Dutta, Sheetij] Walter Reed Army Inst Res, Silver Spring, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 839
BP 247
EP 248
PG 2
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601204
ER
PT J
AU Anderson, KB
Chunsuttiwat, S
Nisalak, A
Jarman, RG
Libraty, DH
Srikiatkhachorn, A
Mammen, MP
Rothman, AL
Gibbons, RV
Endy, TP
AF Anderson, Kathryn B.
Chunsuttiwat, Supamit
Nisalak, Ananda
Jarman, Richard G.
Libraty, Daniel H.
Srikiatkhachorn, Anon
Mammen, Mammen P., Jr.
Rothman, Alan L.
Gibbons, Robert V.
Endy, Timothy P.
TI PATTERNS OF CROSS-REACTIVITY AND SPECIFICITY IN THE SEROLOGICAL RESPONSE
TO DENGUE INFECTION IN KAMPHAENG PHET, THAILAND
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Anderson, Kathryn B.] Emory Univ, Atlanta, GA 30322 USA.
[Chunsuttiwat, Supamit] Minist Publ Hlth, Dept Dis Control, Bangkok, Thailand.
[Nisalak, Ananda; Jarman, Richard G.; Srikiatkhachorn, Anon; Mammen, Mammen P., Jr.; Gibbons, Robert V.] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Libraty, Daniel H.; Rothman, Alan L.] Univ Massachusetts, Sch Med, Worcester, MA USA.
[Endy, Timothy P.] Upstate Med Univ, Syracuse, NY USA.
NR 0
TC 0
Z9 0
U1 1
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 891
BP 262
EP 262
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601256
ER
PT J
AU Ghosh, K
Mendez, J
Braig, HR
Weina, PJ
AF Ghosh, Kashinath
Mendez, Juan
Braig, Henk R.
Weina, Peter J.
TI GENETIC POLYMORPHISM IN THE VISCERALIZING GENE SEQUENCE OF LEISHMANIA
TROPICA ISOLATED FROM THE SOLDIERS RETURNING FROM IRAQ
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Ghosh, Kashinath; Mendez, Juan; Weina, Peter J.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Braig, Henk R.] Bangor Univ, Sch Biol Sci, Bangor, Wales.
RI Weina, Peter/A-2120-2011
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 925
BP 272
EP 272
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601290
ER
PT J
AU Dow, GS
Chen, YF
Andrews, KT
Gerena, L
Gettayacamin, M
Johnson, J
Li, Q
Melendez, V
Obaldia, N
Tran, TN
Kozikowski, A
AF Dow, Geoffrey S.
Chen, Yufeng
Andrews, Katherine T.
Gerena, Lucia
Gettayacamin, Montip
Johnson, Jacob
Li, Qigui
Melendez, Victor
Obaldia, Nicanor, III
Tran, Thanh N.
Kozikowski, Alan
TI ANTIMALARIAL ACTIVITY OF PHENYLTHIAZOLYL-HYDROXAMATE-BASED HISTONE
DEACETYLASE INHIBITORS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Dow, Geoffrey S.; Gerena, Lucia; Johnson, Jacob; Li, Qigui; Melendez, Victor] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Chen, Yufeng] Univ Illinois, Chicago, IL USA.
[Andrews, Katherine T.; Tran, Thanh N.] Queensland Inst Med Res, Brisbane, Qld 4006, Australia.
[Gettayacamin, Montip] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Obaldia, Nicanor, III] Gorgas Mem Inst, Panama City, Panama.
RI Obaldia, Nicanor/O-8460-2015
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 970
BP 285
EP 285
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601335
ER
PT J
AU Tucker, K
Diggs, C
Heppner, DG
Malkin, E
Ockenhouse, CF
Ogutu, BR
Polhemus, ME
Soisson, LA
Withers, MR
Wittes, J
AF Tucker, Kathryn
Diggs, Carter
Heppner, D. Gray
Malkin, Elissa
Ockenhouse, Christian F.
Ogutu, Bernhards R.
Polhemus, Mark E.
Soisson, Lorraine A.
Withers, Mark R.
Wittes, Janet
TI MALARIA SLIDE-READING FOR QUANTITATION OF PARASITEMIA IN MALARIA
INTERVENTION TRIALS: A BETTER TRANSITION POINT FROM THICK TO THIN FILMS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Tucker, Kathryn; Wittes, Janet] Stat Collaborat Inc, Washington, DC USA.
[Diggs, Carter; Soisson, Lorraine A.] US Agcy Int Dev, Malaria Vaccine Dev Program, Washington, DC 20523 USA.
[Heppner, D. Gray; Ockenhouse, Christian F.; Polhemus, Mark E.] Walter Reed Army Inst Res, Div Malaria Vaccine Dev, Silver Spring, MD USA.
[Malkin, Elissa] PATH Malaria Vaccine Initiat, Bethesda, MD USA.
[Ogutu, Bernhards R.] Kenya Govt Med Res Ctr, US Army Med Res Unit Kenya, Nairobi, Kenya.
[Ogutu, Bernhards R.] Kenya Govt Med Res Ctr, Clin Res Ctr, Nairobi, Kenya.
[Withers, Mark R.] USA, Med Res Inst Infect Dis, Div Med, Operat Med Dept, Ft Detrick, MD 21702 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 969
BP 285
EP 285
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601334
ER
PT J
AU Schiehser, GA
Terpinski, J
Ager, AL
McGill, AJ
Milhous, WK
Kyle, DE
Edstein, MD
Rieckmann, KH
Shanks, GD
Sibley, CH
Canfield, CJ
Jacobus, LR
Jacobus, DP
AF Schiehser, Guy A.
Terpinski, Jacek
Ager, Arba L.
McGill, Alan J.
Milhous, Wilbur K.
Kyle, Dennis E.
Edstein, Michael D.
Rieckmann, Karl H.
Shanks, G. Dennis
Sibley, Carol H.
Canfield, Craig J.
Jacobus, Laura R.
Jacobus, David P.
TI PRE-CLINICAL MOUSE TOXICITY STUDY OF THE THIRD GENERATION ANTIFOLATE,
JPC-2056-I
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Schiehser, Guy A.; Terpinski, Jacek; Jacobus, Laura R.; Jacobus, David P.] Jacobus Pharmaceut Co Inc, Princeton, NJ USA.
[Ager, Arba L.] Univ Miami, Sch Med, Miami, FL USA.
[McGill, Alan J.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Milhous, Wilbur K.; Kyle, Dennis E.] Univ S Florida, Tampa, FL USA.
[Edstein, Michael D.; Rieckmann, Karl H.; Shanks, G. Dennis] Australiam Army Malaria Inst, Enoggera, Australia.
[Sibley, Carol H.] Univ Washington, Seattle, WA 98195 USA.
[Canfield, Craig J.] Pharmaceut Syst Inc, Talent, OR USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 973
BP 286
EP 286
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601338
ER
PT J
AU Jin, XN
Sousa, J
Carroll, D
Olmeda, R
Reese, N
Asher, C
Anova, L
Kozar, MF
Melendez, V
AF Jin, Xiannu
Sousa, Jason
Carroll, Dustin
Olmeda, Raul
Reese, Necole
Asher, Constance
Anova, Lalaine
Kozar, Michael F.
Melendez, Victor
TI IN VITRO HEPATIC METABOLISM STUDIES OF PRIMAQUINE AND RELATED
ANTIMALARIAL COMPOUNDS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Jin, Xiannu; Sousa, Jason; Carroll, Dustin; Olmeda, Raul; Reese, Necole; Asher, Constance; Anova, Lalaine; Kozar, Michael F.; Melendez, Victor] Walter Reed Army Inst Res, Div Expt Therapeut, Silver Spring, MD USA.
RI Kozar, Michael/A-9155-2011; Sousa, Jason/A-9177-2011
NR 0
TC 0
Z9 0
U1 2
U2 3
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 978
BP 287
EP 287
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601343
ER
PT J
AU Sousa, J
Milner, E
Jin, XN
Kozar, MF
McCalmont, W
Lanteri, C
Asher, C
Olmeda, R
Carroll, D
Reese, N
Anova, L
Roncal, N
Gerena, L
Obaldia, N
Dow, G
Melendez, V
AF Sousa, Jason
Milner, Erin
Jin, Xiannu
Kozar, Michael F.
McCalmont, William
Lanteri, Charlotte
Asher, Constace
Olmeda, Raul
Carroll, Dustin
Reese, Necole
Anova, Lalaine
Roncal, Normal
Gerena, Lucia
Obaldia, Nicanor
Dow, Geoffrey
Melendez, Victor
TI IN VITRO AND IN VIVO EVALUATIONS OF NEW QUINOLINE METHANOL ANALOGS OF
MEFLOQUINE
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Sousa, Jason; Milner, Erin; Jin, Xiannu; Kozar, Michael F.; McCalmont, William; Lanteri, Charlotte; Asher, Constace; Olmeda, Raul; Carroll, Dustin; Reese, Necole; Anova, Lalaine; Roncal, Normal; Gerena, Lucia; Dow, Geoffrey; Melendez, Victor] Walter Reed Army Inst Res, Div Expt Therapeut, Silver Spring, MD USA.
[Obaldia, Nicanor] Trop Med Res Gorgas Mem Res Inst, Panama City, Panama.
RI Kozar, Michael/A-9155-2011; Sousa, Jason/A-9177-2011; Obaldia,
Nicanor/O-8460-2015
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 979
BP 287
EP 287
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601344
ER
PT J
AU Akala, H
Eyase, F
Omondi, A
Cheruiyot, A
Waitumbi, J
Polhemus, M
Ogutu, B
Waters, N
Johnson, J
Schnabel, D
Walsh, D
AF Akala, Hoseah
Eyase, Fred
Omondi, Angela
Cheruiyot, Agnes
Waitumbi, John
Polhemus, Mark
Ogutu, Bernhards
Waters, Norman
Johnson, Jacob
Schnabel, David
Walsh, Douglas
TI IN VITRO ANTIMALARIAL DRUG SENSITIVITY TRENDS IN KENYAN PLASMODIUM
FALCIPARIUM ISOLATES USING NON-RADIOISOTOPIC SYBR GREEN I FLUORESCENCE
ASSAY AND PFMDR COPY NUMBER ESTIMATION
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
C1 USAMRU Kenya, Walter Reed Project, kisumu, Kenya.
Australian Army Malaria Inst, Enoggera, Australia.
Walter Reed Army Inst Res, Silver Spring, MD USA.
USAMRU Kenya, Water Reed Project, Nairobi, Kenya.
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
SU S
MA 983
BP 288
EP 289
PG 2
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601607
ER
PT J
AU Ubalee, R
Jin, XN
Asher, C
Carrol, D
Jenwithisuk, R
Sattabongkot, J
Richardson, J
Kozar, MP
Melendez, V
AF Ubalee, Ratawan
Jin, Xiannu
Asher, Constance
Carrol, Dustin
Jenwithisuk, Rachaneeporn
Sattabongkot, Jetsumon
Richardson, Jason
Kozar, Michael P.
Melendez, Victor
TI METABOLISM OF CYP450 MARKERS OF ENZYMATIC ACTIVITY AND PRIMAQUINE BY THE
INDUCED HC-04 IMMORTALIZED HEPATIC CELL LINE
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Ubalee, Ratawan; Jenwithisuk, Rachaneeporn; Sattabongkot, Jetsumon; Richardson, Jason] Armed Forces Res Inst Med Sci, US Army Med Component, Bangkok 10400, Thailand.
[Jin, Xiannu; Asher, Constance; Carrol, Dustin; Kozar, Michael P.; Melendez, Victor] Walter Reed Army Inst Res, Div Expt Therapeut, Silver Spring, MD USA.
RI Kozar, Michael/A-9155-2011; Richardson, Jason/A-9441-2011
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 980
BP 288
EP 288
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601345
ER
PT J
AU Sedegah, M
McGrath, S
Regis, D
Chuang, I
Ganeshan, H
Abot, S
Banania, G
Manohar, N
Doolan, D
Limbach, K
House, B
Aguiarl, J
Long, C
Bruder, J
King, C
Patterson, N
Tamminga, C
Epstein, J
Mendoza-Silveiras, J
Williams, F
Soisson, L
Diggs, C
Ockenhouse, C
Richie, T
AF Sedegah, Martha
McGrath, Shannon
Regis, David
Chuang, Ilin
Ganeshan, Harini
Abot, Stephen
Banania, Glena
Manohar, Nalini
Doolan, Denise
Limbach, Keith
House, Brent
Aguiarl, Joao
Long, Carole
Bruder, Joseph
King, Christopher
Patterson, Noelle
Tamminga, Cindy
Epstein, Judith
Mendoza-Silveiras, Jose
Williams, Frank
Soisson, Lorraine
Diggs, Carter
Ockenhouse, Christopher
Richie, Thomas
TI IMMUNOGENICITY OF TWO DOSES OF A MULTI-STAGE, MULTI-ANTIGEN
ADENOVIRUS-VECTORED PLASMODIUM FALCIPARUM MALARIA VACCINE IN A PHASE 1
TRIAL
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Sedegah, Martha; Regis, David; Chuang, Ilin; Ganeshan, Harini; Abot, Stephen; Banania, Glena; Manohar, Nalini; Doolan, Denise; Limbach, Keith; House, Brent; Aguiarl, Joao; Patterson, Noelle; Tamminga, Cindy; Epstein, Judith; Richie, Thomas] USN, Med Res Ctr, Silver Spring, MD USA.
[McGrath, Shannon; Ockenhouse, Christopher] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Long, Carole] NIH, Bethesda, MD 20892 USA.
[Bruder, Joseph; King, Christopher] GenVec, Gaithersburg, MD USA.
[Williams, Frank] Natl Naval Med Ctr, Bethesda, MD USA.
[Soisson, Lorraine; Diggs, Carter] US Agcy Int Dev, Washington, DC 20523 USA.
RI Doolan, Denise/F-1969-2015
NR 0
TC 0
Z9 0
U1 0
U2 3
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 1034
BP 304
EP 304
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601398
ER
PT J
AU Thera, MA
Doumbo, OK
Coulibaly, D
Laurens, MB
Kone, AK
Guindo, AB
Diallo, DA
Traore, K
Diarra, I
Niangaly, A
Dolo, A
Daou, M
Sissoko, M
Sagara, I
Sissoko, MS
Kouriba, B
Lyke, KE
Takala, SL
Godeaux, O
Soisson, L
Lanar, DE
Dutta, S
House, B
Heppner, DG
Plowe, CV
Baby, M
Thonnard, J
Leach, A
Dubois, MC
Cohen, J
Ballou, WR
Diggs, C
Ware, LA
Cummings, JF
Stewart, VA
AF Thera, Mahamadou A.
Doumbo, Ogobara K.
Coulibaly, Drissa
Laurens, Matthew B.
Kone, Abdoulaye K.
Guindo, Ando B.
Diallo, Dapa A.
Traore, Karim
Diarra, Issa
Niangaly, Amadou
Dolo, Amagana
Daou, Modibo
Sissoko, Mady
Sagara, Issaka
Sissoko, Mahamadou S.
Kouriba, Bourema
Lyke, Kirsten E.
Takala, Shannon L.
Godeaux, Olivier
Soisson, Lorraine
Lanar, David E.
Dutta, Sheetij
House, Brent
Heppner, D. Gray
Plowe, Christopher V.
Baby, Mounirou
Thonnard, Joelle
Leach, Amanda
Dubois, Marie-Claude
Cohen, Joe
Ballou, W. Ripley
Diggs, Carter
Ware, Lisa A.
Cummings, James F.
Stewart, V. Ann
TI RANDOMIZED, CONTROLLED, DOSE ESCALATION PHASE 1 CLINICAL TRIAL TO
EVALUATE THE SAFETY AND IMMUNOGENICITY OF WALTER REED ARMY INSTITUTE OF
RESEARCH'S AMA-1 MALARIA VACCINE (FMP2.1) ADJUVANTED IN GSK BIOLOGICALS'
AS02 VS. RABIES VACCINE IN 1-6 YEAR OLD CHILDREN IN BANDIAGARA, MALI
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Thera, Mahamadou A.; Doumbo, Ogobara K.; Coulibaly, Drissa; Kone, Abdoulaye K.; Guindo, Ando B.; Diallo, Dapa A.; Traore, Karim; Diarra, Issa; Niangaly, Amadou; Dolo, Amagana; Daou, Modibo; Sissoko, Mady; Sagara, Issaka; Sissoko, Mahamadou S.; Kouriba, Bourema; Baby, Mounirou] Univ Bamako, Fac Med, Bamako, Mali.
[Laurens, Matthew B.; Lyke, Kirsten E.; Takala, Shannon L.; Plowe, Christopher V.] Univ Maryland, Sch Med, Baltimore, MD 21201 USA.
[Godeaux, Olivier; Leach, Amanda; Dubois, Marie-Claude; Cohen, Joe; Ballou, W. Ripley] GlaxoSmithKline Biol, Rixensart, Belgium.
[Soisson, Lorraine; Diggs, Carter] US Agcy Int Dev, Washington, DC 20523 USA.
[Lanar, David E.; Dutta, Sheetij; House, Brent; Heppner, D. Gray; Ware, Lisa A.; Cummings, James F.; Stewart, V. Ann] Walter Reed Army Inst Res, Silver Spring, MD USA.
RI Lanar, David/B-3560-2011
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 1036
BP 304
EP 305
PG 2
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601400
ER
PT J
AU Patterson, NB
Ganeshan, H
Abot, E
Banania, J
Lejano, JN
Manohar, N
Gowda, K
Limbach, K
McGrath, S
Marshall, SA
Ferrari, ME
Bruder, JT
King, CR
Doolan, DL
Richie, TL
Sedegah, M
AF Patterson, Noelle B.
Ganeshan, Harini
Abot, Esteban
Banania, JoGlenna
Lejano, Jennylynn N.
Manohar, Nalini
Gowda, Kalpana
Limbach, Keith
McGrath, Shannon
Marshall, Stephanie A.
Ferrari, Marilyn E.
Bruder, Joseph T.
King, C. Richter
Doolan, Denise L.
Richie, Thomas L.
Sedegah, Martha
TI A PLASMODIUM FALCIPARUM MULTI-ANTIGEN MULTI-STAGE PLASMID DNA
PRIME/ADENOVECTOR BOOST VACCINE, NMRC-M3V-D/AD-PFCA, IS IMMUNOGENIC IN
BALB/C MICE
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Patterson, Noelle B.; Ganeshan, Harini; Abot, Esteban; Banania, JoGlenna; Lejano, Jennylynn N.; Manohar, Nalini; Gowda, Kalpana; Limbach, Keith; McGrath, Shannon; Marshall, Stephanie A.; Richie, Thomas L.; Sedegah, Martha] US Mil Malaria Vaccine Program, Naval Med Res Ctr, Silver Spring, MD USA.
[Patterson, Noelle B.; Ganeshan, Harini; Abot, Esteban; Banania, JoGlenna; Lejano, Jennylynn N.; Manohar, Nalini; Gowda, Kalpana; Limbach, Keith; McGrath, Shannon; Marshall, Stephanie A.; Richie, Thomas L.; Sedegah, Martha] US Mil Malaria Vaccine Program, Walter Reed Army Inst Res, Silver Spring, MD USA.
[Ferrari, Marilyn E.] Vical Inc, San Diego, CA USA.
[Bruder, Joseph T.; King, C. Richter] GenVec Inc, Gaithersburg, MD USA.
[Doolan, Denise L.] Queensland Inst Med Res, Brisbane, Qld 4006, Australia.
RI Doolan, Denise/F-1969-2015
NR 0
TC 0
Z9 0
U1 0
U2 2
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 1037
BP 305
EP 305
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601401
ER
PT J
AU Dutta, S
Clayton, JW
Spring, MD
Chow, LH
AF Dutta, Sheetij
Clayton, Joshua W.
Spring, Michele D.
Chow, Lin H.
TI RATIONAL DESIGN OF A PAN-REACTIVE APICAL MEMBRANE ANTIGEN-1 BASED
MALARIA VACCINE USING SEROTYPES AND EPITOPE MAPS
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Dutta, Sheetij; Clayton, Joshua W.; Spring, Michele D.; Chow, Lin H.] Walter Reed Army Inst Res, Silver Spring, MD USA.
RI Spring, Michele/B-3564-2011
NR 0
TC 0
Z9 0
U1 0
U2 1
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 1040
BP 306
EP 306
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601404
ER
PT J
AU Husain, T
Richie, TL
Weiss, W
AF Husain, Tupur
Richie, Thomas L.
Weiss, Walter
TI ASSESSING PARASITE BURDEN IN PLASMODIUM KNOWLESI/RHESUS MONKEY
SPOROZOITE CHALLENGE MODEL BY QUANTITATIVE REAL-TIME PCR AND HISTOLOGY
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Husain, Tupur; Richie, Thomas L.; Weiss, Walter] USN, Med Res Ctr, Walter Reed Army Inst Res, Silver Spring, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 1046
BP 307
EP 308
PG 2
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601410
ER
PT J
AU Tachibana, M
Iriko, H
Muratova, O
Song, G
Wu, Y
Sattabongkot, J
Takeo, S
Otsuki, H
Torii, M
Tsuboi, T
AF Tachibana, Mayumi
Iriko, Hideyuki
Muratova, Olga
Song, Guanhong
Wu, Yimin
Sattabongkot, Jetsumon
Takeo, Satoru
Otsuki, Hitoshi
Torii, Motomi
Tsuboi, Takafumi
TI IMMUNIZATION WITH RECOMBINANT PROTEINS OF A GAMETOCYTE PROTEIN PFS230
EXPRESSED USING WHEAT GERM CELL-FREE SYSTEM SUCCESSFULLY INDUCE
TRANSMISSION-BLOCKING ANTIBODIES AGAINST PLASMODIUM FALCIPARUM
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Tachibana, Mayumi; Otsuki, Hitoshi; Torii, Motomi] Ehime Univ, Grad Sch Med, Dept Mol Parasitol, Toon, Ehime, Japan.
[Iriko, Hideyuki] Tottori Univ, Fac Med, Dept Microbiol & Immunol, Tottori 680, Japan.
[Muratova, Olga; Song, Guanhong; Wu, Yimin] NIAID, Malaria Vaccine Dev Branch, Rockville, MD USA.
[Sattabongkot, Jetsumon] Armed Forces Res Inst Med Sci, Dept Entomol, Bangkok 10400, Thailand.
[Takeo, Satoru; Tsuboi, Takafumi] Ehime Univ, Cell Free Sci & Technol Res Ctr, Matsuyama, Ehime, Japan.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 1043
BP 307
EP 307
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601407
ER
PT J
AU Tucker, MS
Peters, J
Nau, M
Wang, ZN
Cheng, Q
Vahey, M
Lukas, S
Azizan, A
Kyle, DE
AF Tucker, Matthew S.
Peters, Jennifer
Nau, Martin
Wang, Zhinning
Cheng, Qin
Vahey, Maryanne
Lukas, Susan
Azizan, Azliyati
Kyle, Dennis E.
TI EXAMINATION OF THE MOLECULAR BASIS OF RESISTANCE TO ARTEMISININ DRUGS IN
PLASMODIUM FALCIPARUM
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Tucker, Matthew S.; Lukas, Susan; Azizan, Azliyati; Kyle, Dennis E.] Univ S Florida, Tampa, FL USA.
[Peters, Jennifer] Queensland Inst Med Res, Brisbane, Qld 4006, Australia.
[Nau, Martin; Wang, Zhinning; Vahey, Maryanne] Walter Reed Army Inst Res, Rockville, MD USA.
RI Azizan, Azliyati/A-6774-2009
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 1122
BP 329
EP 329
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601485
ER
PT J
AU Saunders, D
Li, QQ
Misty, C
Xie, L
Zheng, Q
Zhang, J
Mendez, J
Tally, J
Magill, A
Max, G
Jiang, S
Weina, P
AF Saunders, David
Li, Qiqui
Misty, Carlson
Xie, Lisa
Zheng, Qiang
Zhang, Jing
Mendez, Juan
Tally, John
Magill, Alan
Max, Grogl
Jiang, Suping
Weina, Peter
TI ANTILEISHMANIAL ACTIVITY OF SELECTED FDA-APPROVED DRUGS IN A MURINE
CUTANEOUS LEISHMANIASIS MODEL
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Meeting Abstract
CT 57th Annual Meeting of the
American-Society-of-Tropical-Medicine-and-Hygiene
CY DEC 07-11, 2008
CL New Orleans, LA
SP Amer Soc Trop Med & Hyg
C1 [Saunders, David; Li, Qiqui; Misty, Carlson; Xie, Lisa; Zheng, Qiang; Zhang, Jing; Mendez, Juan; Tally, John; Magill, Alan; Max, Grogl; Jiang, Suping; Weina, Peter] Walter Reed Army Inst Res, Silver Spring, MD USA.
RI Weina, Peter/A-2120-2011
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
MA 1207
BP 355
EP 355
PG 1
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZT
UT WOS:000261644601570
ER
PT J
AU Hartzell, JD
Aronson, NE
Weina, PJ
Howard, RS
Yadava, A
Wortmann, GW
AF Hartzell, Joshua D.
Aronson, Naomi E.
Weina, Peter J.
Howard, Robin S.
Yadava, Anjali
Wortmann, Glenn W.
TI Positive rK39 Serologic Assay Results in US Servicemen with Cutaneous
Leishmaniasis
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Article
ID AMERICAN VISCERAL LEISHMANIASIS; DIRECT AGGLUTINATION-TEST; STRIP-TEST;
IDENTIFICATION; DIAGNOSIS; DIPSTICK; ANTIBODY; CHAGASI; ANTIGEN
AB The rK39 test is a serologic assay for the rapid diagnosis of visceral leishmaniasis (VL). Serum from a North American cohort of 59 otherwise asymptomatic soldiers with cutaneous leishmaniasis (CL) was tested with the rK39 dipstick and ELISA assays, and 10.2%, and 28.8% had positive results, respectively. CL is associated with a reactive rK39 assay result in sonic patients without clinical evidence of VL.
C1 Walter Reed Army Med Ctr, Div Infect Dis, Washington, DC 20307 USA.
Uniformed Serv Univ Hlth Sci, Div Infect Dis, Bethesda, MD 20814 USA.
Walter Reed Army Med Ctr, Dept Clin Invest, Washington, DC 20307 USA.
Walter Reed Army Inst Res, Silver Spring, MD USA.
RP Hartzell, JD (reprint author), Walter Reed Army Med Ctr, Div Infect Dis, BLD 2,Ward 63,0900 Georgia Ave NW, Washington, DC 20307 USA.
EM joshua.hartzell@amedd.army.mil
RI Weina, Peter/A-2120-2011
FU Infectious Disease Clinical Research Program and Military Infectious
Disease Research Program
FX This study was supported by the Infectious Disease Clinical Research
Program and Military Infectious Disease Research Program.
NR 13
TC 9
Z9 9
U1 0
U2 0
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
BP 843
EP 846
PG 4
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZR
UT WOS:000261644400007
PM 19052290
ER
PT J
AU Hillesland, H
Read, A
Subhadra, B
Hurwitz, I
McKelvey, R
Ghosh, K
Das, P
Durvasula, R
AF Hillesland, Heidi
Read, Amber
Subhadra, Bobban
Hurwitz, Ivy
McKelvey, Robin
Ghosh, Kashinath
Das, Pradeep
Durvasula, Ravi
TI Identification of Aerobic Gut Bacteria from the Kala Azar Vector,
Phlebotomus argentipes: A Platform for Potential Paratransgenic
Manipulation of Sand Flies
SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
LA English
DT Article
ID BREVIBACTERIUM-CASEI; GORDONIA-TERRAE; STAPHYLOCOCCUS-COHNII;
HOSPITALIZED-PATIENTS; LEISHMANIA-DONOVANI; BACILLUS-SUBTILIS;
INFECTION; DISEASE; CHOLANGITIS; SEPTICEMIA
AB Visceral leishmaniasis is an understudied parasitic disease responsible for significant global morbidity and mortality. We are presently investigating a method of disease prevention termed paratransgenesis. In this approach, symbiotic or commensal bacteria are transformed to produce anti-Leishmania molecules. The transformed bacteria are delivered back to sand flies to inactivate the parasite within the vector itself. In this study, we identified 28 distinct gut microorganisms from Phlebotomus argentipes trapped from four visceral leishmaniasis-endemic sites in India. A significant percent of Staphylococcus spp., environmental bacteria, and Enterobacteriaceae were identified. Two non-pathogenic organisms. Bacillus megaterium and Brevibacterium linens, were also isolated. Both organisms are also Used extensively in industry. Our results indicate that B. megaterium and B. linens are possible candidates for use in a model of paratransgenesis to prevent transmission of Leishmania.
C1 Univ New Mexico, Dept Internal Med, Albuquerque, NM 87131 USA.
Rajendra Mem Res Inst Med Sci, Patna, Bihar, India.
Walter Reed Army Inst Res, Silver Spring, MD USA.
RP Durvasula, R (reprint author), Univ New Mexico, Dept Internal Med, Albuquerque, NM 87131 USA.
EM ravi.durvasula@va.gov
NR 45
TC 30
Z9 31
U1 2
U2 10
PU AMER SOC TROP MED & HYGIENE
PI MCLEAN
PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA
SN 0002-9637
J9 AM J TROP MED HYG
JI Am. J. Trop. Med. Hyg.
PD DEC
PY 2008
VL 79
IS 6
BP 881
EP 886
PG 6
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 382ZR
UT WOS:000261644400014
PM 19052297
ER
PT J
AU Szpisjak, DF
Javernick, EN
Kyle, RR
Austin, PN
AF Szpisjak, Dale F.
Javernick, Elizabeth N.
Kyle, Richard R.
Austin, Paul N.
TI Oxygen Consumption of a Pneumatically Controlled Ventilator in a Field
Anesthesia Machine
SO ANESTHESIA AND ANALGESIA
LA English
DT Article
ID MECHANICAL VENTILATION
AB BACKGROUND: Field anesthesia machines (FAM) have been developed for remote locations where reliable supplies of compressed medical gases or electricity may be absent. In place of electricity, pneumatically controlled ventilators use compressed gas to power timing circuitry and actuate valves. We sought to determine the total O(2) consumption and ventilator gas Consumption (drive gas [DG] plus pneumatic control [PC] gas) of a FAM's Pneumatically controlled ventilator in mechanical models of high (HC) and low (LC) total thoracic compliance.
METHODS: The amount of total O(2) consumed by the Magellan-2200 (Oceanic Medical Products, Atchison, KS) FAM with pneumatically controlled ventilator was calculated using the ideal gas law and the measured mass of O(2) consumed from E cylinders. DG to the bellows canister assembly was measured with the Wright Respirometer Mk 8 (Ferraris Respiratory Europe, Hertford, UK). PC gas consumption was calculated by subtracting DG and fresh gas flow (FGF) from the total O(2) Consumed from the E cylinder. The delivered tidal volume (V(T)) was measured with a pneumotach (Hans Rudolph, KS City, MO). Three different V, were tested (500, 750, and 1.000 mL) with two lung models (HC and LC) using the Vent Aid Training Test Lung (MI Instruments, Grand Rapids, MI). Respiratory variables included all I:E of 1:2, FGF of 1 L/min, and respiratory rate of 10 breaths/min.
RESULTS: Total O(2) consumption was directly proportional to V(T) and inversely proportional to compliance. The smallest total O(2) consumption rate (including FGF) was 9.3 +/- 0.4 L/min in the HC-500 model and the largest was 15.9 +/- 0.5 L/min in the LC-1000 model (P < 0.001.). The mean PC circuitry consumption was 3.9 +/- 0.24 L/min or 390 mL +/- 24 mL/breath.
CONCLUSIONS: To prepare for loss of central DG supply, patient safety will be improved by estimating cylinder duration for low total thoracic compliance. Using data from the smaller compliance and greatest V(T) model (LC-1000), a full O(2) E cylinder Would be depleted in <42 min, whereas a full H cylinder would last approximately 433 min.
C1 [Szpisjak, Dale F.] Uniformed Serv Univ Hlth Sci, Dept Anesthesiol, Bethesda, MD 20814 USA.
[Javernick, Elizabeth N.] Walter Reed Army Med Ctr, Dept Anesthesiol, Washington, DC 20307 USA.
[Kyle, Richard R.] Uniformed Serv Univ Hlth Sci, Dept Anat Physiol & Genet, Bethesda, MD 20814 USA.
[Austin, Paul N.] Uniformed Serv Univ Hlth Sci, Grad Sch Nursing, Bethesda, MD 20814 USA.
RP Szpisjak, DF (reprint author), Uniformed Serv Univ Hlth Sci, Dept Anesthesiol, 4301 Jones Bridge Rd, Bethesda, MD 20814 USA.
EM dszpisjak@usuhs.mil
FU Defense Advanced Research Projects Agency, Arlington, VA
FX Supported by a grant from the Defense Advanced Research Projects Agency,
Arlington, VA.
NR 6
TC 3
Z9 3
U1 0
U2 1
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0003-2999
J9 ANESTH ANALG
JI Anesth. Analg.
PD DEC
PY 2008
VL 107
IS 6
BP 1907
EP 1911
DI 10.1213/ane.0b013e31818a04da
PG 5
WC Anesthesiology
SC Anesthesiology
GA 376PZ
UT WOS:000261196800024
PM 19020137
ER
PT J
AU Stojadinovic, A
Elster, EA
Anam, K
Tadaki, D
Amare, M
Zins, S
Davis, TA
AF Stojadinovic, Alexander
Elster, Eric A.
Anam, Khairul
Tadaki, Douglas
Amare, Mihret
Zins, Stephen
Davis, Thomas A.
TI Angiogenic response to extracorporeal shock wave treatment in murine
skin isografts
SO ANGIOGENESIS
LA English
DT Article
DE Angiogenesis; Extracorporeal shock wave therapy; Skin graft; Wound
healing
ID ENDOTHELIAL PROGENITOR CELLS; VACUUM-ASSISTED CLOSURE;
GROWTH-FACTOR-BETA; FLAP SURVIVAL; GENE-THERAPY; BONE-MARROW;
ELECTRICAL-STIMULATION; ISCHEMIC NECROSIS; MODEL; ULTRASOUND
AB Skin grafts are commonly utilized and proven effective methods of open wound coverage. Revascularization through neoangiogenesis is a pivotal mechanism for skin graft integration and durability. Extracorporeal shock-wave treatment (ESWT) has been demonstrated to accelerate wound repair; however, its mechanism-of-action is unclear. We investigated the role of ESWT in early revascularization of full-thickness skin isografts in a murine model. Cohorts of mice were euthanized and skin grafts were harvested 6 h, 2, 4, and 7 days post grafting +/- A ESWT. Various aspects of graft neovascularization were measured including gross morphology, quantitative microscopy (vessel number, density), immunohistochemistry (CD31), cDNA SuperArrays for 84 angiogenesis-specific genes, and custom-designed 'Wound Repair' TaqMan(A (R)) Low Density Array (TLDA) cards to assess expression of 188 wound repair genes. We demonstrate that a single administration of ESWT immediately following skin grafting significantly enhances recipient graft revascularization (increased vessel number, size, and density). An augmented early pro-angiogenic and suppressed delayed pro-inflammatory response to ESWT was accompanied by significantly increased expression of both skin graft CD31 and angiogenesis pathway-specific genes, including ELR-CXC chemokines (CXCL1, CXCL2, CXCL5), CC chemokines (CCL2, CCL3, CCL4), cytokines (IL-1 beta, IL-6, G-CSF, VEGF-A), matrix metalloproteinases (MMP3, MMP9, MMP13), hypoxia-inducible factors (HIF-1 alpha), and vascular remodeling kinase (Mst1), as early as 6 h and up to 7 days post grafting and treatment. These findings suggest that early pro-angiogenic and anti-inflammatory effects of ESWT promote tissue revascularization and wound healing by augmenting angiogenesis and dampening inflammation.
C1 [Elster, Eric A.; Anam, Khairul; Tadaki, Douglas; Amare, Mihret; Zins, Stephen; Davis, Thomas A.] USN, Regenerat Med Dept, Med Res Ctr, Silver Spring, MD 20910 USA.
[Elster, Eric A.] Natl Naval Med Ctr, Combat Wound Initiat Program, Dept Surg, Bethesda, MD USA.
[Stojadinovic, Alexander; Davis, Thomas A.] Walter Reed Army Med Ctr, Dept Surg, Combat Wound Initiat Program, Washington, DC 20307 USA.
[Stojadinovic, Alexander; Elster, Eric A.; Tadaki, Douglas] Uniformed Serv Univ Hlth Sci, Dept Surg, Bethesda, MD 20814 USA.
RP Davis, TA (reprint author), USN, Regenerat Med Dept, Med Res Ctr, Room 2A10,503 Robert Grant Ave, Silver Spring, MD 20910 USA.
EM thomas.davis1@med.navy.mil
FU ONR [602236N.42237, W160.A0806]; Henry M. Jackson Foundation
FX This work was supported by ONR work unit 602236N.42237. W160.A0806 and
by the Combat Wound Initiative Program, a Congressionally funded program
of the Henry M. Jackson Foundation for the Advancement of Military
Medicine.
NR 54
TC 54
Z9 55
U1 2
U2 4
PU SPRINGER
PI DORDRECHT
PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
SN 0969-6970
J9 ANGIOGENESIS
JI Angiogenesis
PD DEC
PY 2008
VL 11
IS 4
BP 369
EP 380
DI 10.1007/s10456-008-9120-6
PG 12
WC Peripheral Vascular Disease
SC Cardiovascular System & Cardiology
GA 392NP
UT WOS:000262309700006
PM 18998221
ER
PT J
AU Abadie, JM
Koelsch, AA
AF Abadie, Jude M.
Koelsch, Angela A.
TI Performance of the Roche second generation hemoglobin A1c immunoassay in
the presence of Hb-S or Hb-C traits
SO ANNALS OF CLINICAL AND LABORATORY SCIENCE
LA English
DT Article
DE hemoglobin A1c; hemoglobinopathies; HbS; HbC; diabetes mellitus; HbA1c
immunoassay
ID GLYCOHEMOGLOBIN METHODS; HBA(1C); VARIANTS; DERIVATIVES; ANALYZER;
A(1C); HPLC
AB Blood HbA1c determination is a powerful tool for the evaluation and management of patients with diabetes mellitus. Many HbA1c analytical methods demonstrate bias in samples from patients with hemoglobinopathies. This study evaluated the analytical performance of Roche Diagnostics' 1st and 2nd generation HbA1c assays in patients with or without hemoglobinopathies whose HbA1c levels were elevated or normal, respectively. Boronate-affinity high performance liquid chromatography (HPLC) served as the reference method. Whole blood samples were collected from 80 patients with HbS or HbC whose group mean HbA1c value was elevated and also from 80 patients without hemoglobinopathy whose HbA1c values were in the well-controlled range. Each sample was assayed for HbA1c by the Primus boronate-affinity HPLC technique and by Roche's 1st and 2nd generation immunoassays using a Cobas Integra 800 analytical system. Results by the HPLC technique were compared with the results of both Roche assays by linear regression and Bland-Altman analysis. The 1st and 2nd generation assays yielded regression lines and correlation values vs HPLC assay of y = 1.43x - 1.59; R-2 = 0.83, and y = 0.94x + 0.10; R-2 = 0.92, respectively, in the 80 patients with hemoglobinopathies. The mean difference and the +/- 2SD range were greater in the 1st than in the 2nd generation assay (2.68, +/- 2.07 vs -0-54, +/- 0.86, respectively). The 2nd generation assay also showed better performance than the 1st generation assay in samples from the 80 patients without hemoglobinopathy. In conclusion, this study validates the accuracy of Roche's 2nd generation assay, which is substantially improved over Roche's 1st generation HbA1c assay.
C1 [Abadie, Jude M.; Koelsch, Angela A.] Walter Reed Army Med Ctr, Core Lab, Dept Pathol, Washington, DC 20307 USA.
RP Abadie, JM (reprint author), Walter Reed Army Med Ctr, Core Lab, Dept Pathol, 6900 Georgia Ave,NW, Washington, DC 20307 USA.
EM jude.abadie@amedd.army.mil
NR 21
TC 16
Z9 18
U1 1
U2 2
PU ASSOC CLINICAL SCIENTISTS
PI MIDDLEBURY
PA PO BOX 1287, MIDDLEBURY, VT 05753 USA
SN 0091-7370
J9 ANN CLIN LAB SCI
JI Ann. Clin. Lab. Sci.
PD WIN
PY 2008
VL 38
IS 1
BP 31
EP 36
PG 6
WC Medical Laboratory Technology
SC Medical Laboratory Technology
GA 267ER
UT WOS:000253492800006
PM 18316779
ER
PT J
AU Moran, ML
Greenfield, RJ
Wilson, DK
AF Moran, Mark L.
Greenfield, Roy J.
Wilson, D. Keith
TI Acoustic array tracking performance under moderately complex
environmental conditions (vol 68, pg 1241, 2007)
SO APPLIED ACOUSTICS
LA English
DT Correction
C1 [Moran, Mark L.; Greenfield, Roy J.; Wilson, D. Keith] USA, Corps Engineers, Engineer Res & Dev Ctr, Hanover, NH 03755 USA.
RP Moran, ML (reprint author), USA, Corps Engineers, Engineer Res & Dev Ctr, 72 Lyme Rd, Hanover, NH 03755 USA.
EM mark.l.moran@erdc.usace.army.mil
RI Wilson, D. Keith/A-4687-2012
OI Wilson, D. Keith/0000-0002-8020-6871
NR 1
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0003-682X
J9 APPL ACOUST
JI Appl. Acoust.
PD DEC
PY 2008
VL 69
IS 12
BP 1368
EP 1368
DI 10.1016/j.apacoust.2007.11.003
PG 1
WC Acoustics
SC Acoustics
GA 369QI
UT WOS:000260708600025
ER
PT J
AU Vanderploeg, RD
Schwab, K
Walker, WC
Fraser, JA
Sigford, BJ
Date, ES
Scott, SG
Curtiss, G
Salazar, AM
Warden, DL
AF Vanderploeg, Rodney D.
Schwab, Karen
Walker, William C.
Fraser, Jamie A.
Sigford, Barbara J.
Date, Elaine S.
Scott, Steven G.
Curtiss, Glenn
Salazar, Andres M.
Warden, Deborah L.
CA Defense Vet Brain Injury Ctr Study
TI Rehabilitation of Traumatic Brain Injury in Active Duty Military
Personnel and Veterans: Defense and Veterans Brain Injury Center
Randomized Controlled Trial of Two Rehabilitation Approaches
SO ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
LA English
DT Article
DE Brain injuries; Cognition; Rehabilitation; Treatment outcome
ID COGNITIVE REHABILITATION; HEAD-INJURY; UNITED-STATES; RATING-SCALE;
INTERVENTION; DISABILITY; INTENSITY; CLINICIAN; EFFICACY; MODERATE
AB Objectives: To determine the relative efficacy of 2 different acute traumatic brain injury (TBI) rehabilitation approaches: cognitive didactic versus functional-experiential and secondarily to determine relative efficacy for different patient subpopulations.
Design: Randomized, controlled, intent-to-treat trial comparing 2 alternative TBI treatment approaches.
Setting: Four Veterans Administration acute inpatient TBI rehabilitation programs.
Participants: Adult veterans or active duty military service members (N=360) with moderate to severe TBI.
Interventions: One and a half to 2.5 hours of protoco specific cognitive-didactic versus functional-experiential rehabilitation therapy integrated into interdisciplinary acute Commission for Accreditation of Rehabilitation Facilities-accredited inpatient TBI rehabilitation programs with another 2 to 2.5 hours daily of occupational and physical therapy. Duration of protocol treatment varied from 20 to 60 days depending on the clinical needs and progress of each participant.
Main Outcome Measures: The 2 primary outcome measures were functional independence in living and return to work and/or school assessed by independent evaluators at 1-year follow-up. Secondary outcome measures consisted of the FIM, Disability Rating Scale score, and items from the Present State Exam, Apathy Evaluation Scale, and Neurobehavioral Rating Scale.
Results: The cognitive-didactic and functional-experiential treatments did not result in overall group differences in the broad 1-year primary outcomes. However, analysis of secondary outcomes found differentially better immediate posttreatment cognitive function (mean +/- SD cognitive FIM) in participants randomized to cognitive-didactic treatment (27.3 +/- 6.2) than to functional treatment (25.6 +/- 6.0, t(332)=2.56, P=.01). Exploratory subgroup analyses found that younger participants in the cognitive arm had a higher rate of returning to work or school than younger patients in the functional arm, whereas participants older than 30 years and those with more years of education in the functional arm had higher rates of independent living status at 1 year posttreatment than similar patients in the cognitive arm.
Conclusions: Results from this large multicenter randomized controlled trial comparing cognitive-didactic and functional-experiential approaches to brain injury rehabilitation indicated improved but similar long-term global functional outcome. Participants in the cognitive treatment arm achieved better short-term functional cognitive performance than patients in the functional treatment arm. The current increase in war-related brain injuries provides added urgency for rigorous study of rehabilitation treatments. (http://ClinicalTrials.gov ID# NCT00540020.)
C1 [Vanderploeg, Rodney D.; Curtiss, Glenn] James A Haley Vet Affairs Med Ctr, Dept Mental Hlth & Behav Sci, Tampa, FL 33612 USA.
[Vanderploeg, Rodney D.; Curtiss, Glenn] James A Haley Vet Affairs Med Ctr, Def & Vet Brain Injury Ctr, Tampa, FL 33612 USA.
[Vanderploeg, Rodney D.; Curtiss, Glenn] Univ S Florida, Dept Psychiat & Behav Med, Tampa, FL USA.
[Vanderploeg, Rodney D.] Univ S Florida, Dept Psychol, Tampa, FL 33620 USA.
[Schwab, Karen; Fraser, Jamie A.; Warden, Deborah L.] Walter Reed Army Med Ctr, Def & Vet Brain Injury Ctr, Washington, DC 20307 USA.
[Schwab, Karen; Warden, Deborah L.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
[Walker, William C.] Hunter H McGuire Vet Affairs Med Ctr, Def & Vet Brain Injury Ctr, Richmond, VA USA.
[Walker, William C.] Virginia Commonwealth Univ, Sch Med, Dept Phys Med & Rehabil, Richmond, VA USA.
[Sigford, Barbara J.] Minneapolis Vet Affairs Med Ctr, Minneapolis, MN USA.
[Date, Elaine S.] Vet Affairs Palo Alto Hlth Care Syst, Comprehens Rehabil Ctr, Palo Alto, CA USA.
[Date, Elaine S.] Stanford Univ, Sch Med, Dept Orthopaed Surg, Stanford, CA 94305 USA.
[Scott, Steven G.] James A Haley Vet Affairs Med Ctr, Polytrauma Rehabil Ctr, Phys Med & Rehabil Serv, Tampa, FL 33612 USA.
[Scott, Steven G.] Univ S Florida, Coll Med, Dept Internal Med, Phys Med & Rehabil Sect, Tampa, FL 33612 USA.
[Salazar, Andres M.] Oncovir Inc, Washington, DC USA.
RP Vanderploeg, RD (reprint author), James A Haley Vet Affairs Med Ctr, Dept Mental Hlth & Behav Sci, 116B,13000 N Bruce B Downs Blvd, Tampa, FL 33612 USA.
EM Rodney.Vanderploeg@va.gov
RI Walker, William/N-3162-2014
NR 49
TC 61
Z9 61
U1 5
U2 23
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0003-9993
J9 ARCH PHYS MED REHAB
JI Arch. Phys. Med. Rehabil.
PD DEC
PY 2008
VL 89
IS 12
BP 2227
EP 2238
DI 10.1016/j.apmr.2008.06.015
PG 12
WC Rehabilitation; Sport Sciences
SC Rehabilitation; Sport Sciences
GA 385GY
UT WOS:000261803900001
PM 19061734
ER
PT J
AU Chinnawirotpisan, P
Mammen, MP
Nisalak, A
Thaisomboonsuk, B
Narupiti, S
Thirawuth, V
Putnak, R
Zhang, CL
AF Chinnawirotpisan, P.
Mammen, M. P., Jr.
Nisalak, A.
Thaisomboonsuk, B.
Narupiti, S.
Thirawuth, V.
Putnak, R.
Zhang, Chunlin
TI Detection of concurrent infection with multiple dengue virus serotypes
in Thai children by ELISA and nested RT-PCR assay
SO ARCHIVES OF VIROLOGY
LA English
DT Article
ID POLYMERASE CHAIN-REACTION; CO-CIRCULATION; MOSQUITO; IDENTIFICATION;
BANGKOK; DENV-3; TYPE-2; FEVER
AB The prevailing global spread of four dengue virus (DENV) serotypes and the resultant co-circulation of multiple serotypes in the same region have invariably led to conditions supporting the periodic occurrence of simultaneous infection of individuals with more than one DENV serotype. This raises the issue of how best to detect concurrent multiple infections. We report here the use of a nested reverse transcription-polymerase chain reaction (RT-PCR) assay, which detected concurrent infection with three DENV serotypes (DENV-1/DENV-2/DENV-3) and two serotypes (DENV-1/DENV-2 and DENV-2/DENV-4), respectively, in three serum specimens from Thai children hospitalized during the dengue epidemic of 2000-2001. In contrast, an enzyme-linked immunosorbent assay used previously for virus serotype identification failed to detect multiple DENV serotypes in these specimens. Serotype identification by RT-PCR was confirmed by sequence analysis of each amplified PCR product. Phylogenetic analyses performed on PCR-amplified DNA fragments further supported the occurrence of concurrent infections with multiple DENV serotypes in these children. Although the sample set was small, our data suggest that nested RT-PCR is an effective method for the detection of concurrent DENV infections.
C1 [Putnak, R.; Zhang, Chunlin] Walter Reed Army Inst Res, Div Viral Dis, Silver Spring, MD 20910 USA.
[Chinnawirotpisan, P.; Mammen, M. P., Jr.; Nisalak, A.; Thaisomboonsuk, B.; Narupiti, S.; Thirawuth, V.; Zhang, Chunlin] USA, Med Component Armed Forces Res Inst Med Sci, Dept Virol, Bangkok, Thailand.
RP Zhang, CL (reprint author), Walter Reed Army Inst Res, Div Viral Dis, 503 Robert Grant Ave, Silver Spring, MD 20910 USA.
EM chunlin.zhang@amedd.army.mil
FU US Military Infectious Disease Research Program, Fort Detrick, Maryland,
USA
FX We thank the doctors and nurses of QSNICH/AFRIMS for specimen collection
and clinical grading. We gratefully acknowledge Dr. Yuxin Tang, Tao Li
and Richard Zhao for assistance with the manuscript preparation. This
research was supported by the US Military Infectious Disease Research
Program, Fort Detrick, Maryland, USA. The opinions or assertions
contained herein are the private views of the authors and are not to be
construed as reflecting the official views of the US Army or the
Department of Defense.
NR 28
TC 15
Z9 17
U1 0
U2 3
PU SPRINGER WIEN
PI WIEN
PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 WIEN, AUSTRIA
SN 0304-8608
J9 ARCH VIROL
JI Arch. Virol.
PD DEC
PY 2008
VL 153
IS 12
BP 2225
EP 2232
DI 10.1007/s00705-008-0249-9
PG 8
WC Virology
SC Virology
GA 391KJ
UT WOS:000262231900006
PM 19011729
ER
PT J
AU Vogt, DS
Proctor, SP
King, DW
King, LA
Vasterling, JJ
AF Vogt, Dawne S.
Proctor, Susan P.
King, Daniel W.
King, Lynda A.
Vasterling, Jennifer J.
TI Validation of Scales From the Deployment Risk and Resilience Inventory
in a Sample of Operation Iraqi Freedom Veterans
SO ASSESSMENT
LA English
DT Article
DE war-zone exposure; military deployments; veterans; Operation Iraqi
Freedom; psychometric evaluation
ID POSTTRAUMATIC-STRESS-DISORDER; MALE VIETNAM VETERANS; MENTAL-HEALTH
PROBLEMS; WAR-ZONE STRESSORS; LIFE-EVENTS; PSYCHOLOGICAL-ASSESSMENT;
MILITARY PERSONNEL; CONSTRUCT-VALIDITY; MEDICAL OUTCOMES; NATIONAL
SAMPLE
AB The Deployment Risk and Resilience Inventory (DRRI) is a suite of scales that can be used to assess deployment-related factors implicated in the health and well-being of military veterans. Although initial evidence for the reliability and validity of DRRI scales based on Gulf War veteran samples is encouraging, evidence with respect to a more contemporary cohort of Operation Iraqi Freedom (OIF) veterans is not available. Therefore, the primary goal of the present study was to validate scales from the DRRI in a large sample of OIF army personnel diversified in occupational and demographic characteristics. In general, results supported the use of these DRRI scales in this population. Internal consistency reliability estimates were quite strong. Additionally, support was obtained for criterion-related validity, as demonstrated by associations with mental and physical health measures, and discriminative validity, as demonstrated by differences between key military subgroups.
C1 [Vogt, Dawne S.] Boston Univ, Natl Ctr PTSD, Womens Hlth Sci Div, VA Boston Healthcare Syst,Dept Psychiat,Sch Med, Boston, MA 02215 USA.
[King, Lynda A.] Boston Univ, Natl Ctr PTSD, Womens Hlth Sci Div, VA Boston Healthcare Syst,Dept Psychol, Boston, MA 02215 USA.
[King, Daniel W.] Boston Univ, Natl Ctr PTSD, VA Boston Healthcare Syst, Behav Sci Div,Dept Psychol, Boston, MA 02215 USA.
[Vasterling, Jennifer J.] Boston Univ, Natl Ctr PTSD, VA Boston Healthcare Syst, Behav Sci Div,Dept Psychiat,Sch Med,Psychol Serv, Boston, MA 02215 USA.
[Proctor, Susan P.] Boston Univ, VA Boston Healthcare Syst, Dept Environm Hlth,Sch Publ Hlth,Res Serv, USA,Res Inst Environm Med,Mil Performance Div, Boston, MA 02215 USA.
RP Vogt, DS (reprint author), VA Boston Healthcare Syst 116B5, Womens Hlth Sci Div, 150 S Huntington Ave, Boston, MA 02130 USA.
EM dawne.vogt@va.gov
NR 67
TC 34
Z9 34
U1 3
U2 12
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1073-1911
J9 ASSESSMENT
JI Assessment
PD DEC
PY 2008
VL 15
IS 4
BP 381
EP 403
DI 10.1177/1073191108316030
PG 13
WC Psychology, Clinical
SC Psychology
GA 373TN
UT WOS:000260996500001
ER
PT J
AU Yeh, IC
Olson, MA
Lee, MS
Wallqvist, A
AF Yeh, In-Chul
Olson, Mark A.
Lee, Michael S.
Wallqvist, Anders
TI Free-Energy Profiles of Membrane Insertion of the M2 Transmembrane
Peptide from Influenza A Virus
SO BIOPHYSICAL JOURNAL
LA English
DT Article
ID MOLECULAR-DYNAMICS SIMULATIONS; HISTOGRAM ANALYSIS METHOD;
COMPUTER-SIMULATIONS; REPLICA-EXCHANGE; LIPID-BILAYERS; PROTON CHANNELS;
SIDE-CHAINS; PROTEINS; MODEL; RECOGNITION
AB The insertion of the M2 transmembrane peptide from influenza A virus into a membrane has been studied with molecular-dynamics simulations. This system is modeled by an atomically detailed peptide interacting with a continuum representation of a membrane bilayer in aqueous solution. We performed replica-exchange molecular-dynamics simulations with umbrella-sampling techniques to characterize the probability distribution and conformation preference of the peptide in the solution, at the membrane interface, and in the membrane. The minimum in the calculated free-energy surface of peptide insertion corresponds to a fully inserted, helical peptide spanning the membrane. The free-energy profile also shows that there is a significant barrier for the peptide to enter into this minimum in a nonhelical conformation. The sequence of the peptide is such that hydrophilic amino acid residues at the ends of the otherwise primarily hydrophobic peptide create a trapped, U-shaped conformation with the hydrophilic residues associated with the aqueous phase and the hydrophobic residues embedded in the membrane. Analysis of the free energy shows that the barrier to insertion is largely enthalpic in nature, whereas the membrane-spanning global minimum is favored by entropy.
C1 [Yeh, In-Chul; Lee, Michael S.; Wallqvist, Anders] USA, Biotechnol HPC Software Applicat Inst, Med Res & Mat Command, Telemed & Adv Technol Res Ctr,ATTN MCMR TT, Ft Detrick, MD 21702 USA.
[Olson, Mark A.; Lee, Michael S.] USA, Med Res Inst Infect Dis, Dept Cell Biol & Biochem, Ft Detrick, MD 21702 USA.
[Lee, Michael S.] USA, Res Lab, Computat & Informat Sci Directorate, Aberdeen Proving Ground, MD USA.
RP Yeh, IC (reprint author), USA, Biotechnol HPC Software Applicat Inst, Med Res & Mat Command, Telemed & Adv Technol Res Ctr,ATTN MCMR TT, Bldg 363 Miller Dr, Ft Detrick, MD 21702 USA.
EM icy@bioanalysis.org
OI wallqvist, anders/0000-0002-9775-7469
NR 52
TC 9
Z9 9
U1 0
U2 10
PU CELL PRESS
PI CAMBRIDGE
PA 600 TECHNOLOGY SQUARE, 5TH FLOOR, CAMBRIDGE, MA 02139 USA
SN 0006-3495
EI 1542-0086
J9 BIOPHYS J
JI Biophys. J.
PD DEC 1
PY 2008
VL 95
IS 11
BP 5021
EP 5029
DI 10.1529/biophysj.108.133579
PG 9
WC Biophysics
SC Biophysics
GA 373UR
UT WOS:000260999500004
PM 18676651
ER
PT J
AU Casadevall, A
Ehrlich, SA
Franz, DR
Imperiale, MJ
Keim, PS
AF Casadevall, Arturo
Ehrlich, Susan A.
Franz, David R.
Imperiale, Michael J.
Keim, Paul S.
TI BIODEFENSE RESEARCH: A WIN-WIN CHALLENGE
SO BIOSECURITY AND BIOTERRORISM-BIODEFENSE STRATEGY PRACTICE AND SCIENCE
LA English
DT Editorial Material
C1 [Casadevall, Arturo] Yeshiva Univ, Albert Einstein Coll Med, Div Infect Dis, Bronx, NY USA.
[Ehrlich, Susan A.] Arizona Court Appeals, Phoenix, AZ USA.
[Franz, David R.] USA, Med Res Inst Infect Dis, Frederick, MD USA.
[Imperiale, Michael J.] Univ Michigan, Sch Med, Dept Microbiol & Immunol, Ann Arbor, MI 48109 USA.
[Keim, Paul S.] No Arizona Univ, Dept Biol, Flagstaff, AZ 86011 USA.
[Keim, Paul S.] Translat Genom Res Inst, Pathogen Genom Div, Flagstaff, AZ USA.
RP Casadevall, A (reprint author), Yeshiva Univ, Albert Einstein Coll Med, Div Infect Dis, Bronx, NY USA.
RI Keim, Paul/A-2269-2010
FU NIAID NIH HHS [U54 AI057158]
NR 0
TC 0
Z9 0
U1 0
U2 1
PU MARY ANN LIEBERT INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1538-7135
J9 BIOSECUR BIOTERROR
JI Biosecur. Bioterror.
PD DEC
PY 2008
VL 6
IS 4
BP 291
EP 292
DI 10.1089/bsp.2008.1114
PG 2
WC Public, Environmental & Occupational Health; International Relations
SC Public, Environmental & Occupational Health; International Relations
GA 389YB
UT WOS:000262130400005
PM 19090664
ER
PT J
AU Parnell, GS
Borio, LL
Brown, GG
Banks, D
Wilson, AG
AF Parnell, Gregory S.
Borio, Luciana L.
Brown, Gerald G.
Banks, David
Wilson, Alyson G.
TI SCIENTISTS URGE DHS TO IMPROVE BIOTERRORISM RISK ASSESSMENT
SO BIOSECURITY AND BIOTERRORISM-BIODEFENSE STRATEGY PRACTICE AND SCIENCE
LA English
DT Article
AB In 2006, the Department of Homeland Security (DHS) completed its first Bioterrorism Risk Assessment (BTRA), intended to be the foundation for DHS's subsequent biennial risk assessments mandated by Homeland Security Presidential Directive 10 (HSPD-10). At the request of DHS, the National Research Council established the Committee on Methodological Improvements to the Department of Homeland Security's Biological Agent Risk Analysis to provide an independent, scientific peer review of the BTRA. The Committee found a number of shortcomings in the BTRA, including a failure to consider terrorists as intelligent adversaries in their models, unnecessary complexity in threat and consequence modeling and simulations, and a lack of focus on risk management. The Committee unanimously concluded that an improved BTRA is needed to provide a more credible foundation for risk-informed decision making.
C1 [Parnell, Gregory S.] US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA.
[Borio, Luciana L.] Univ Pittsburgh, Med Ctr, Ctr Biosecur, Baltimore, MD USA.
[Brown, Gerald G.] USN, Postgrad Sch, Dept Operat Res, Monterey, CA USA.
[Banks, David] Duke Univ, Dept Stat & Decis Sci, Durham, NC USA.
[Wilson, Alyson G.] Iowa State Univ, Dept Stat, Ames, IA USA.
RP Parnell, GS (reprint author), US Mil Acad, Dept Syst Engn, West Point, NY 10996 USA.
EM gregory.parnell@usma.edu
OI Wilson, Alyson/0000-0003-1461-6212
NR 7
TC 7
Z9 7
U1 0
U2 4
PU MARY ANN LIEBERT INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1538-7135
J9 BIOSECUR BIOTERROR
JI Biosecur. Bioterror.
PD DEC
PY 2008
VL 6
IS 4
BP 353
EP 356
DI 10.1089/bsp.2008.0930
PG 4
WC Public, Environmental & Occupational Health; International Relations
SC Public, Environmental & Occupational Health; International Relations
GA 389YB
UT WOS:000262130400012
PM 18976117
ER
PT J
AU Wolf, SE
AF Wolf, Steven E.
TI The year in burns 2007
SO BURNS
LA English
DT Review
DE Burn research articles; Topics of clinical burn care
ID PARTIAL-THICKNESS BURNS; ACUTE LUNG INJURY; INHALATION INJURY;
RISK-FACTORS; DONOR-SITE; RANDOMIZED-TRIAL; HEALING-PROCESS;
THERMAL-INJURY; BASE DEFICIT; YOUNG-ADULTS
AB In the year 2007, approximately 1000 original burn research articles were published in scientific journals using the English language. This article reviews approximately 90 of these which were deemed by the author to be the most important in terms of clinical burn care. Relevant topics include epidemiology, wound characterisation, critical care physiology, inhalation injury, infection, metabolism and nutrition, psychological considerations, pain management, rehabilitation, and burn reconstruction. Each selected article is mentioned briefly with editorial comment. Published by Elsevier Ltd and ISBI
C1 [Wolf, Steven E.] Univ Texas Hlth Sci Ctr San Antonio, Dept Surg, San Antonio, TX 78229 USA.
[Wolf, Steven E.] USA, Inst Surg Res, San Antonio, TX 78229 USA.
RP Wolf, SE (reprint author), Univ Texas Hlth Sci Ctr San Antonio, Dept Surg, 7703 Floyd Curl, San Antonio, TX 78229 USA.
EM wolfs@uthscsa.edu
OI Wolf, Steven/0000-0003-2972-3440
NR 88
TC 7
Z9 8
U1 1
U2 3
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0305-4179
J9 BURNS
JI Burns
PD DEC
PY 2008
VL 34
IS 8
BP 1059
EP 1071
DI 10.1016/j.burns.2008.05.029
PG 13
WC Critical Care Medicine; Dermatology; Surgery
SC General & Internal Medicine; Dermatology; Surgery
GA 380IP
UT WOS:000261459700001
PM 18786767
ER
PT J
AU Murray, CK
Loo, FL
Hospenthal, DR
Cancio, LC
Jones, JA
Kim, SH
Holcomb, JB
Wade, CE
Wolf, SE
AF Murray, Clinton K.
Loo, Florence L.
Hospenthal, Duane R.
Cancio, Leopoldo C.
Jones, John A.
Kim, Seung H.
Holcomb, John B.
Wade, Charles E.
Wolf, Steven E.
TI Incidence of systemic fungal infection and related mortality following
severe burns
SO BURNS
LA English
DT Article
DE Fungus; Mortality; Burn; Attributable mortality
ID SURGICAL PATIENTS; WOUND-INFECTION; COLONIZATION
AB Advancements in burn care therapy have extended survival of seriously burned patients, exposing burn patients to increased risk of infectious complications, notably fungal infections. We performed a 12-year review of autopsied patients with severe bums for the presence of fungal infection at the US Army Institute of Surgical Research Burn Center between February 1991 and November 2003. The primary goal was to identify the relationship between fungal element noted in autopsy and mortality, and to determine contributing factors that increase a patient's susceptibility to fungal infection. A total of 228 deaths (6.1%) resulted from the 3751 admissions of which 97 underwent autopsy. Fungal elements were identified on histopathology in 44% (43 of 97) of autopsied patients with an attributable mortality of 33% (14 of 43). Aspergillus and Candida were the most frequently recovered fungi, but Aspergillus was recovered in 13 of the 14 cases with fungus identified as an attributable cause of death. The most common sites of infections with attributable mortality were wounds (86%) and the pulmonary system (14%). Total body surface area (TBSA) burn and length of stay (survival after burn) were identified as contributing factors for the incidence of fungal element in autopsy on ROC curve analysis. More severely injured patients with greater %TBSA burn injury and full-thickness burns require a longer recovery period resulting in a longer hospital stay. The propensity for fungal infection increases the longer the wound is present. Therefore, the development of products to close the wound more rapidly, improvement in topical antifungal therapy with mold activity for treating wounds, and implementation of appropriate systemic antifungal therapy may improve outcome for severely injured burn victims susceptible to fungal infections. Published by Elsevier Ltd and ISBI
C1 [Murray, Clinton K.] Brooke Army Med Ctr, San Antonio Mil Med Ctr, Infect Dis Serv, Ft Sam Houston, TX 78234 USA.
[Loo, Florence L.; Cancio, Leopoldo C.; Jones, John A.; Kim, Seung H.; Holcomb, John B.; Wade, Charles E.; Wolf, Steven E.] USA, Inst Surg Res, Washington, DC USA.
[Murray, Clinton K.; Hospenthal, Duane R.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
RP Murray, CK (reprint author), Brooke Army Med Ctr, San Antonio Mil Med Ctr, Infect Dis Serv, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA.
EM Clinton.Murray@amedd.army.mil
OI Wolf, Steven/0000-0003-2972-3440
NR 10
TC 47
Z9 48
U1 1
U2 2
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0305-4179
J9 BURNS
JI Burns
PD DEC
PY 2008
VL 34
IS 8
BP 1108
EP 1112
DI 10.1016/j.burns.2008.04.007
PG 5
WC Critical Care Medicine; Dermatology; Surgery
SC General & Internal Medicine; Dermatology; Surgery
GA 380IP
UT WOS:000261459700007
PM 18691821
ER
PT J
AU Keefer, ML
Wertheimer, RH
Evans, AF
Boggs, CT
Peery, CA
AF Keefer, Matthew L.
Wertheimer, Robert H.
Evans, Allen F.
Boggs, Charles T.
Peery, Christopher A.
TI Iteroparity in Columbia River summer-run steelhead (Oncorhynchus
mykiss): implications for conservation
SO CANADIAN JOURNAL OF FISHERIES AND AQUATIC SCIENCES
LA English
DT Article
ID SALMON SALMO-SALAR; LIFE-HISTORY CHARACTERISTICS; JUVENILE CHINOOK
SALMON; ATLANTIC SALMON; SALVELINUS-ALPINUS; DELAYED MORTALITY;
HYDROELECTRIC DAM; ADULT STEELHEAD; SOCKEYE-SALMON; BYPASS SYSTEM
AB We used ultrasound imaging and passive integrated transponder (PIT)-tagging programs to assess maturation status and iteroparity patterns in summer-run steelhead (anadromous rainbow trout, Oncorhynchus mykiss) of the interior Columbia River Basin (Pacific Northwest, USA). Postspawn kelts examined in downstream fish bypass systems at Columbia River and Snake River dams were disproportionately female (> 80%) and majorities were of wild origin, unlike prespawn steelhead at these sites. Annual repeat migration estimates varied from 2.9% to 9.0% for kelts tagged at lower Columbia River dams (n = 2542) and from 0.5% to 1.2% for Snake River kelts (n = 3762). Among-site differences reflected greater outmigration distance and additional dam passage hazards for Snake River kelts. There was also strong evidence for condition-dependent mortality, with returns an order of magnitude higher for good-versus poor-condition kelts. Disproportionately more females and wild fish also returned, providing potentially valuable genetic and demographic benefits for the Columbia River's threatened steelhead populations. Results overall provide baseline data for evaluating kelt mortality mitigation efforts and basic life history information for steelhead conservation planning.
C1 [Keefer, Matthew L.; Boggs, Charles T.; Peery, Christopher A.] Univ Idaho, Dept Fish & Wildlife Resources, Moscow, ID 83844 USA.
[Wertheimer, Robert H.] USA, Corps Engineers, Portland, OR 97208 USA.
[Evans, Allen F.] Real Time Res Inc, Bend, OR 97702 USA.
RP Keefer, ML (reprint author), Univ Idaho, Dept Fish & Wildlife Resources, Moscow, ID 83844 USA.
EM mkeefer@uidaho.edu
NR 79
TC 31
Z9 31
U1 2
U2 20
PU CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS
PI OTTAWA
PA 1200 MONTREAL ROAD, BUILDING M-55, OTTAWA, ON K1A 0R6, CANADA
SN 0706-652X
EI 1205-7533
J9 CAN J FISH AQUAT SCI
JI Can. J. Fish. Aquat. Sci.
PD DEC
PY 2008
VL 65
IS 12
BP 2592
EP 2605
DI 10.1139/F08-160
PG 14
WC Fisheries; Marine & Freshwater Biology
SC Fisheries; Marine & Freshwater Biology
GA 386UT
UT WOS:000261908800004
ER
PT J
AU Amin, A
Benavides, LC
Holmes, JP
Gates, JD
Carmichael, MG
Hueman, MT
Mittendorf, EA
Storrer, CE
Jama, YH
Craig, D
Stojadinovic, A
Ponniah, S
Peoples, GE
AF Amin, Asna
Benavides, Linda C.
Holmes, Jarrod P.
Gates, Jeremy D.
Carmichael, Mark G.
Hueman, Matthew T.
Mittendorf, Elizabeth A.
Storrer, Catherine E.
Jama, Yusuf H.
Craig, Dianna
Stojadinovic, Alex
Ponniah, Sathibalan
Peoples, George E.
TI Assessment of immunologic response and recurrence patterns among
patients with clinical recurrence after vaccination with a preventive
HER2/neu peptide vaccine: from US Military Cancer Institute Clinical
Trials Group Study I-01 and I-02
SO CANCER IMMUNOLOGY IMMUNOTHERAPY
LA English
DT Article
DE vaccine; E75 peptide; preventive; recurrence; pathologic patterns;
immunologic response
ID HER2-POSITIVE BREAST-CANCER; ADJUVANT CHEMOTHERAPY; METASTATIC BREAST;
OVARIAN-CANCER; E75 VACCINE; T-CELLS; HER-2/NEU; IMMUNITY; IMMUNIZATION;
TRASTUZUMAB
AB Background E75, a HER2/neu immunogenic peptide, is expressed in breast cancer (BCa). We have performed clinical trials of E75 + GM-CSF vaccine in disease-free, node-positive and node-negative BCa patients at high recurrence risk and recurrences were noted in both control and vaccine groups. Methods Among the 186 BCa patients enrolled, 177 completed the study. Patients were HLA typed; the HLA-A2(+)/A3(+) patients were vaccinated; HLA-A2(-)/A3(-) patients were followed as controls. Standard clinicopathological factors, immunologic response to the vaccine, and recurrences were collected and assessed.
Results The control group recurrence rate was 14.8 and 8.3% in the vaccinated group (P = 0.17). Comparing the 8 vaccinated recurrences (V-R) to the 88 vaccinated nonrecurrent patients (V-NR), the V-R group had higher nodal stage (>= N2: 75 vs. 5%, P = 0.0001) and higher grade tumors (% grade 3: 88 vs. 31%, P = 0.003). The V-R group did not fail to respond immunologically as noted by equivalent dimer responses and post-DTH responses. Compared to control recurrent patients (C-R), V-R patients trended toward higher-grade tumors and hormone-receptor negativity. C-R patients had 50% bone-only recurrences, compared to V-R patients with no bone-only recurrences (P = 0.05). Lastly, V-R mortality rate was 12.5% compared with 41.7% for the C-R group (P = 0.3).
Conclusions The vaccinated patients who recurred had more aggressive disease compared to V-NR patients. V-R patients had no difference in immune response to the vaccine either in vitro or in vivo. V-R patients, when compared to C-R patients, trended towards more aggressive disease, decreased recurrence rates, decreased mortality, and no bone-only recurrences.
C1 [Benavides, Linda C.; Gates, Jeremy D.; Peoples, George E.] Brooke Army Med Ctr, Dept Surg, Gen Surg Serv, Ft Sam Houston, TX 78234 USA.
[Amin, Asna; Stojadinovic, Alex] Walter Reed Army Med Ctr, Dept Surg, Gen Surg Serv, Washington, DC 20307 USA.
[Holmes, Jarrod P.] USN, San Diego Med Ctr, Div Hematol & Med Oncol, Dept Med, San Diego, CA 92152 USA.
[Carmichael, Mark G.; Hueman, Matthew T.; Storrer, Catherine E.; Jama, Yusuf H.; Ponniah, Sathibalan; Peoples, George E.] Uniformed Serv Univ Hlth Sci, Dept Surg, Canc Vaccine Dev Program, US Mil Canc Inst, Bethesda, MD 20814 USA.
[Mittendorf, Elizabeth A.] UTMD Anderson Canc Ctr, Houston, TX USA.
[Craig, Dianna] Windber Med Ctr, Joyce Murtha Breast Care Ctr, Windber, PA USA.
RP Peoples, GE (reprint author), Brooke Army Med Ctr, Dept Surg, Gen Surg Serv, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA.
EM george.peoples@amedd.army.mil
NR 33
TC 18
Z9 19
U1 0
U2 2
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0340-7004
J9 CANCER IMMUNOL IMMUN
JI Cancer Immunol. Immunother.
PD DEC
PY 2008
VL 57
IS 12
BP 1817
EP 1825
DI 10.1007/s00262-008-0509-2
PG 9
WC Oncology; Immunology
SC Oncology; Immunology
GA 351GI
UT WOS:000259412300007
PM 18392824
ER
PT J
AU Hermone, AR
Burnett, JC
Nuss, JE
Tressler, LE
Nguyen, TL
Solaja, BA
Vennerstrom, JL
Schmidt, JJ
Wipf, P
Bavari, S
Gussio, R
AF Hermone, Ann R.
Burnett, James C.
Nuss, Jonathan E.
Tressler, Lyal E.
Nguyen, Tam L.
Solaja, Bogdan A.
Vennerstrom, Jonathan L.
Schmidt, James J.
Wipf, Peter
Bavari, Sina
Gussio, Rick
TI Three-Dimensional Database Mining Identifies a Unique Chemotype that
Unites Structurally Diverse Botulinum Neurotoxin Serotype A Inhibitors
in a Three-Zone Pharmacophore
SO CHEMMEDCHEM
LA English
DT Article
DE molecular modeling; screening; drug discovery; biologically active
compounds; botulinum neurotoxin
ID TOXIN TYPE-A; ZINC ENDOPEPTIDASE; NEUROTRANSMITTER RELEASE;
CLOSTRIDIUM-BOTULINUM; PROTEOLYTIC ACTIVITY; PROTEASE INHIBITORS;
UNLABELED USES; VAMP/SYNAPTOBREVIN; CHEMISTRY; THERAPY
AB A search query consisting of two aromatic centers and two cationic centers was defined based on previously identified small molecule inhibitors of the botulinum neurotoxin serotype A light chain (BoNT/A LC) and used to mine the National Cancer Institute Open Repository. Ten small molecule hits were identified, and upon testing, three demonstrated inhibitory activity. Of these, one was structurally unique, possessing a rigid diazochrysene scaffold. The steric limitations of the diazachrysene imposed a separation between the overlaps of previously identified inhibitors, revealing an extended binding mode. As a result, the pharmacophore for BoNT/A LC inhibition has been modified to encompass three zones. To demonstrate the utility of this model, a novel three-zone inhibitor was mined and its activity was confirmed.
C1 [Hermone, Ann R.; Burnett, James C.; Nguyen, Tam L.] NCI, SAIC Frederick Inc, Target Struct Based Drug Discovery Grp, Frederick, MD 21702 USA.
[Nuss, Jonathan E.; Tressler, Lyal E.; Schmidt, James J.; Bavari, Sina] USA, Med Res Inst Infect Dis, Frederick, MD 21702 USA.
[Solaja, Bogdan A.] Univ Belgrade, Fac Chem, Belgrade 11001, Serbia.
[Vennerstrom, Jonathan L.] Univ Nebraska Med Ctr, Coll Pharm, Omaha, NE 68198 USA.
[Wipf, Peter] Univ Pittsburgh, Combinatorial Chem Ctr, Pittsburgh, PA 15260 USA.
[Gussio, Rick] NCI, Informat Technol Branch, Dev Therapeut Program, Frederick, MD 21702 USA.
RP Hermone, AR (reprint author), NCI, SAIC Frederick Inc, Target Struct Based Drug Discovery Grp, POB 8, Frederick, MD 21702 USA.
EM sina.bavari@us.army.mil; gussio@ncifcrf.gov
OI Solaja, Bogdan/0000-0002-9975-2725
FU Defense Threat Reduction Agency [3.10024 06]; MRMC; NCI; National
Institutes of Health; National Cancer Institute [N01-CO-12400]
FX This research was funded by Defense Threat Reduction Agency project
3.10024 06 RD B and Interagency Agreement Y3 CM 100505 (MRMC and NCI,
National Institutes of Health). Additionally, this project has been
funded in whole or in port with federal funds from the National Cancer
Institute, National Institutes of Health, under contract N01-CO-12400.
The content of this publication does not necessarily reflect the views
or policies of the Department of Health and Human Services, nor does
mention of trade names, commercial products, or organizations imply
endorsement by the U.S. Government. This research was supported [in
part] by the Developmental Therapeutics Program in the Division of
Cancer Treatment and Diagnosis of the National Cancer Institute.
NR 46
TC 28
Z9 28
U1 0
U2 3
PU WILEY-V C H VERLAG GMBH
PI WEINHEIM
PA PO BOX 10 11 61, D-69451 WEINHEIM, GERMANY
SN 1860-7179
J9 CHEMMEDCHEM
JI ChemMedChem
PD DEC
PY 2008
VL 3
IS 12
BP 1905
EP 1912
DI 10.1002/cmdc.200800241
PG 8
WC Chemistry, Medicinal; Pharmacology & Pharmacy
SC Pharmacology & Pharmacy
GA 386IO
UT WOS:000261877100011
PM 19006141
ER
PT J
AU Ricart, AD
Tolcher, AW
Liu, G
Holen, K
Chwartz, GS
Albertini, M
Weiss, G
Yazji, S
Ng, C
Wilding, G
AF Ricart, Alejandro D.
Tolcher, Anthony W.
Liu, Glenn
Holen, Kyle
Schwartz, Garry
Albertini, Mark
Weiss, Geoffrey
Yazji, Salim
Ng, Chee
Wilding, George
TI Volociximab, a Chimeric Monoclonal Antibody that Specifically Binds
alpha(5)beta(1) Integrin: A Phase I, Pharmacokinetic, and Biological
Correlative Study
SO CLINICAL CANCER RESEARCH
LA English
DT Article; Proceedings Paper
CT 16th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer
Therapeutics
CY SEP 28-OCT 01, 2004
CL Geneva, SWITZERLAND
SP EORTC, NCI, AACR
ID CYTOPLASMIC DOMAIN; MELANOMA-CELLS; FIBRONECTIN; EXPRESSION;
ALPHA-5-BETA-1; ANGIOGENESIS; TRASTUZUMAB; ENVIRONMENT; INHIBITION;
SURVIVAL
AB Purpose: This study aimed to assess the safety and feasibility of administering volociximab, a chimeric monoclonal antibody that specifically binds to alpha(5)beta(1) integrin, and to determine the pharmacokinetics, pharmacodynamics, and preliminary evidence of antitumor activity.
Experimental Design: Patients with advanced solid malignancies were treated with escalating doses of volociximab i.v. administered over 60 minutes. Blood samples were assayed to determine plasma pharmacokinetic parameters, detect human antichimeric antibody formation, and determine the saturation of alpha(5)beta(1) sites on peripheral blood monocytes.
Results: Twenty-one patients received 223 infusions of volociximab at doses ranging from 0.5 to 15 mg/kg i.v. on days 1, 15, 22, 29, and 36; and weekly thereafter. Treatment was well tolerated, and dose-limiting toxicity was not identified over the range examined. Mild (grade 1 or 2), reversible fatigue was the principal toxicity of volociximab at the highest dose levels of 10 and 15 mg/kg. Nausea, fever, anorexia, headache, vomiting, and myalgias were mild and infrequent, and there was no hematologic toxicity. Volociximab had biexponential distribution; clearance was inversely related to increasing dose, and the half-life at 15 mg/kg was estimated as being 30 days. Three patients tested positive for anti-volociximab antibodies. Saturation of monocyte alpha(5)beta(1) integrin sites was dose-dependent up to 15 mg/kg. There was one minor response (renal, 7 months) and one durable stable disease (melanoma, 14 months).
Conclusions: Volociximab can be safely administered at 15 mg/kg i.v. per week. The absence of severe toxicities and preliminary activity at the highest dose level warrants further disease-directed studies.
C1 [Ricart, Alejandro D.; Tolcher, Anthony W.; Weiss, Geoffrey; Ng, Chee] Canc Therapy & Res Ctr S Texas, Inst Drug Dev, San Antonio, TX 78229 USA.
[Ricart, Alejandro D.; Tolcher, Anthony W.; Weiss, Geoffrey; Ng, Chee] Univ Texas Hlth Sci Ctr San Antonio, San Antonio, TX 78229 USA.
[Schwartz, Garry] Brooke Army Med Ctr, San Antonio, TX USA.
[Liu, Glenn; Holen, Kyle; Albertini, Mark; Wilding, George] Univ Wisconsin, Paul P Carbone Comprehens Canc Ctr, Madison, WI USA.
[Yazji, Salim] PDL Biopharma Inc, Fremont, CA USA.
RP Tolcher, AW (reprint author), START Inst S Texas Accelerated Res Therapeut, 4319 Med Dr,Suite 205, San Antonio, TX 78229 USA.
EM atolcher@start.stoh.com
FU NCI NIH HHS [P30 CA014520-36, P30 CA014520-37, P30 CA014520, P30
CA014520-38]
NR 28
TC 77
Z9 79
U1 0
U2 1
PU AMER ASSOC CANCER RESEARCH
PI PHILADELPHIA
PA 615 CHESTNUT ST, 17TH FLOOR, PHILADELPHIA, PA 19106-4404 USA
SN 1078-0432
J9 CLIN CANCER RES
JI Clin. Cancer Res.
PD DEC 1
PY 2008
VL 14
IS 23
BP 7924
EP 7929
DI 10.1158/1078-0432.CCR-08-0378
PG 6
WC Oncology
SC Oncology
GA 379JK
UT WOS:000261392300043
PM 19047123
ER
PT J
AU Brown, JM
Berkey, BD
Brooks, JA
AF Brown, Jerry M.
Berkey, Bryan D.
Brooks, John A.
TI Discovery of a Renal Medullary Carcinoma in an Adolescent Male With
Sickle Cell Trait by Tc-99m Methylene Disphosponate Bone Scintigraphy
SO CLINICAL NUCLEAR MEDICINE
LA English
DT Editorial Material
DE renal medullary carcinoma; sickle cell trait; hemoglobin SC disease;
bone scintigraphy
ID SCANS
AB The renal excretion of Tc-99m bone imaging agents often permits the identification of urinary tract abnormalities on bone scans. In this case report, identification of focal intrarenal stasis of the excreted bone imaging agent led to additional anatomic imaging and the identification of a renal medullary carcinoma (RMC) in an adolescent black male undergoing evaluation for back pain. RMC is a rare, highly aggressive renal neoplasm found almost exclusively in young individuals with sickle cell trait (SCT) or hemoglobin SC disease. The prognosis of RMC is poor because the malignancy is usually refractory to chemotherapy and radiotherapy, with metastatic disease commonly present at the time of diagnosis.
C1 [Brown, Jerry M.; Berkey, Bryan D.] Tripler Army Med Ctr, Dept Radiol, Honolulu, HI 96859 USA.
[Brooks, John A.] Michigan State Univ, Coll Human Med, E Lansing, MI 48824 USA.
RP Brown, JM (reprint author), Tripler Army Med Ctr, Dept Radiol, 1 Jarrett White Rd, Honolulu, HI 96859 USA.
EM jerry.brown@amedd.army.mil
NR 8
TC 1
Z9 1
U1 0
U2 2
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0363-9762
J9 CLIN NUCL MED
JI Clin. Nucl. Med.
PD DEC
PY 2008
VL 33
IS 12
BP 896
EP 900
DI 10.1097/RLU.0b013e31818bf31d
PG 5
WC Radiology, Nuclear Medicine & Medical Imaging
SC Radiology, Nuclear Medicine & Medical Imaging
GA 376VS
UT WOS:000261211700024
PM 19033803
ER
PT J
AU Banks, KP
Song, WS
AF Banks, Kevin P.
Song, Won S.
TI Acetabular Impingement on Planar and SPECT Bone Scintigraphy
SO CLINICAL NUCLEAR MEDICINE
LA English
DT Editorial Material
DE scintigraphy; hip pain; femoroacetabular impingement (FAI)
ID MR ARTHROGRAPHIC FINDINGS; FEMOROACETABULAR IMPINGEMENT; HIP; CAM
AB A 37-year-old male presented with 4 months of atraumatic left hip pain. Onset of symptoms began during basic military training and pain was exacerbated by physical activity. Plain film radiographs of the hip were reported as normal. Because of the concern for a potential stress fracture, the patient was referred to nuclear medicine for bone scintigraphy. Planar and SPECT imaging revealed the presence of abnormal scintigraphic activity involving both hips (left greater than right) in a distribution atypical for stress injury and more consistent with bilateral femoral acetabular impingement (FAI). Subsequent MR examination was confirmed the diagnosis. This case illustrates a novel method for evaluating the physiologic process of FAI.
C1 [Banks, Kevin P.] Brooke Army Med Ctr, Dept Radiol, Ft Sam Houston, TX 78234 USA.
Brooke Army Med Ctr, Dept Nucl Med, Ft Sam Houston, TX 78234 USA.
RP Banks, KP (reprint author), Brooke Army Med Ctr, Dept Radiol, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA.
EM KPBanks@gmail.com
NR 9
TC 1
Z9 2
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0363-9762
J9 CLIN NUCL MED
JI Clin. Nucl. Med.
PD DEC
PY 2008
VL 33
IS 12
BP 916
EP 919
DI 10.1097/RLU.0b013e31818c4e6c
PG 4
WC Radiology, Nuclear Medicine & Medical Imaging
SC Radiology, Nuclear Medicine & Medical Imaging
GA 376VS
UT WOS:000261211700030
PM 19033809
ER
PT J
AU Potter, BK
Adams, SC
Pitcher, JD
Temple, HT
AF Potter, Benjamin K.
Adams, Sheila C.
Pitcher, J. David, Jr.
Temple, H. Thomas
TI Local Recurrence of Disease after Unplanned Excisions of High-grade Soft
Tissue Sarcomas
SO CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
LA English
DT Article
ID LIMB-SPARING SURGERY; RADIATION-THERAPY; RE-EXCISION; SUBCUTANEOUS
SARCOMA; SURGICAL RESECTION; ANATOMIC LOCATION; RESIDUAL DISEASE;
LOWER-EXTREMITY; SURVIVAL; MANAGEMENT
AB Unplanned excisions of soft tissue sarcomas occur with alarming frequency and result in high rates of residual disease, potentially affecting patient prognosis. To determine if unplanned excisions and residual disease status at tumor bed excision increased local recurrence rates and predicted disease-specific patient survival, we retrospectively reviewed 203 consecutive patients with highgrade soft tissue sarcomas treated operatively and followed for at least 2 years (mean, 4.8 years) or until patient death. Among the 64 patients (32%) who had undergone previous unplanned excisions, six had gross residual disease and 40 of the remaining 58 (69%) had microscopic residual disease in the tumor bed. We observed subsequent local recurrence in nine of the 139 patients (6%) after planned excision compared with 22 patients (34%) after unplanned excision. More patients with unplanned excisions who underwent limb salvage procedures required flap coverage and/or skin grafting with their definitive resection (30% versus 5%). In the unplanned excision cohort, residual disease status at tumor bed excision predicted increased rates of local recurrence and decreased disease-specific survival. Unplanned excisions of high-grade soft tissue sarcomas resulted in increased rates of local recurrence but not disease-specific survival. Residual disease at reexcision predicted the likelihood of local recurrence.
C1 [Potter, Benjamin K.] Walter Reed Army Med Ctr, Integrated Dept Orthopaed & Rehabil, Washington, DC 20307 USA.
[Temple, H. Thomas] Univ Miami, Miller Sch Med, Dept Orthopaed, Miami, FL 33136 USA.
RP Potter, BK (reprint author), Walter Reed Army Med Ctr, Integrated Dept Orthopaed & Rehabil, 6900 Georgia Ave NW,Bldg 2A,Room 205, Washington, DC 20307 USA.
EM Benjamin.potter@amedd.army.mil
OI Potter, MD, Benjamin K./0000-0002-8771-0317
NR 46
TC 35
Z9 35
U1 0
U2 1
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0009-921X
J9 CLIN ORTHOP RELAT R
JI Clin. Orthop. Rel. Res.
PD DEC
PY 2008
VL 466
IS 12
BP 3093
EP 3100
DI 10.1007/s11999-008-0529-4
PG 8
WC Orthopedics; Surgery
SC Orthopedics; Surgery
GA 383RG
UT WOS:000261690500026
PM 18818981
ER
PT J
AU Uzarski, JR
Tannous, A
Morris, JR
Mello, CM
AF Uzarski, Joshua R.
Tannous, Abla
Morris, John R.
Mello, Charlene M.
TI The effects of solution structure on the surface conformation and
orientation of a cysteine-terminated antimicrobial peptide cecropin P1
SO COLLOIDS AND SURFACES B-BIOINTERFACES
LA English
DT Article
DE Antimicrobial peptide; Surface structure
ID INFRARED REFLECTION ABSORPTION; VIBRATIONAL SPECTROSCOPY; GOLD SURFACE;
HYDROPHOBIC POLYSTYRENE; MOLECULAR-CONFORMATION; HYDROPHILIC SILICA;
PROTEIN-STRUCTURE; ESCHERICHIA-COLI; ADSORPTION; MONOLAYERS
AB The surface structure of an antimicrobial peptide, cecropin P1, immobilized to a gold surface via a terminal cysteine residue was investigated. Using reflection-absorption infrared spectroscopy, surface plasmon resonance, and X-ray photoelectron spectroscopy, the effects of pH,solution conformation, and concentration on the immobilized peptide conformation, average orientation, and surface density were determined. Under all conditions investigated, the immobilized peptides were a-helical in a predominately flat, random orientation. The addition of the reducing agent Tris(2-carboxyethyl) phosphine hydrochloride to the buffer resulted in a twofold increase in immobilized peptide surface density. Published by Elsevier B.V.
C1 [Mello, Charlene M.] USA, NSRDEC, Biosci & Technol Team, Natick, MA 01760 USA.
[Uzarski, Joshua R.; Morris, John R.] Virginia Tech, Dept Chem, Blacksburg, VA 24061 USA.
[Tannous, Abla; Mello, Charlene M.] Univ Massachusetts, Dept Chem & Biochem, Dartmouth, MA 02743 USA.
RP Mello, CM (reprint author), USA, NSRDEC, Biosci & Technol Team, Kansas St, Natick, MA 01760 USA.
EM charlene.mello@us.army.mil
FU U.S. Army NSRDEC [AH52]
FX We respectfully thank Professors Bal Ram Singh and Shuowei Cai for the
use of Jasco J-715 spectropolarimeter and valuable discussions. Special
gratitude is alos extended to Dr. Jennifer Becker from the Army Research
Office for technical and programmatic support. This research was
supported by the U.S. Army NSRDEC AH52 basic research program. This
manuscript has been approved for unlimited distribution by the U.S. Army
Natick Soldier Research, Development and Engineering Center
[PAO#08-208].
NR 52
TC 22
Z9 22
U1 0
U2 13
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0927-7765
J9 COLLOID SURFACE B
JI Colloid Surf. B-Biointerfaces
PD DEC 1
PY 2008
VL 67
IS 2
BP 157
EP 165
DI 10.1016/j.colsurfb.2008.07.011
PG 9
WC Biophysics; Chemistry, Physical; Materials Science, Biomaterials
SC Biophysics; Chemistry; Materials Science
GA 383HV
UT WOS:000261665600002
PM 18945601
ER
PT J
AU Ahmad, FH
Castellane, RM
Miller, EL
AF Ahmad, Falih H.
Castellane, Ray M.
Miller, Ernest L.
TI On the applicability of the pseudospectral Legendre method for edge
detection
SO COMMUNICATIONS IN NUMERICAL METHODS IN ENGINEERING
LA English
DT Article
DE pseudospectral method; gradient detector; edge detection
AB The pseudospectral Legendre method is utilized to develop a gradient detector. This detector is proposed in this communication for the detection of edges in discrete images. The detector can be applied in both the horizontal and vertical directions. It is a separable detector where the smoothing orthogonal part resembles a one-dimensional notch filter. Discrete Canny's criteria values of the detector are similar to those of other known basic derivative filters. An example is given in which this detector is utilized and its applicability and validity are supported using comparison results from the use of the Sobel filter. Copyright (C) 2007 John Wiley & Sons, Ltd.
C1 [Ahmad, Falih H.] Tarleton State Univ, Dept Math Phys & Engn, Stephenville, TX 76402 USA.
[Castellane, Ray M.; Miller, Ernest L.] Engineer Res & Dev Ctr, Dept Army, Vicksburg, MS 39180 USA.
RP Ahmad, FH (reprint author), Tarleton State Univ, Dept Math Phys & Engn, Box T-390, Stephenville, TX 76402 USA.
EM ahmad@tarleton.edu
FU Department of Defense, Engineering Research and Development Center. ERDC
[W912HZ-06-P-0007]
FX This work was Supported by the Department of Defense, Engineering
Research and Development Center. ERDC, Vicksburg, Mississippi, U.S.A.
under contract W912HZ-06-P-0007. The authors Would like to C extend
their sincere thanks to Mrs Pamela Kinnebrew, Chief, Survivability
Engineering Branch, ERDC. Z, C Permission was granted by the Chief of
Engineers from ERDC to publish this information.
NR 8
TC 0
Z9 0
U1 0
U2 1
PU JOHN WILEY & SONS LTD
PI CHICHESTER
PA THE ATRIUM, SOUTHERN GATE, CHICHESTER PO19 8SQ, W SUSSEX, ENGLAND
SN 1069-8299
J9 COMMUN NUMER METH EN
JI Commun. Numer. Methods Eng.
PD DEC
PY 2008
VL 24
IS 12
BP 1805
EP 1810
DI 10.1002/cnm.1068
PG 6
WC Engineering, Multidisciplinary; Mathematics, Interdisciplinary
Applications
SC Engineering; Mathematics
GA 384XY
UT WOS:000261778700014
ER
PT J
AU Ku, BC
Kim, DW
Steeves, D
Nagarajan, R
Blumstein, A
Kumar, J
Gibson, PW
Ratto, JA
Samuelson, LA
AF Ku, Bon-Cheol
Kim, Dong Wook
Steeves, Diane
Nagarajan, Ramaswamy
Blumstein, Alexandre
Kumar, Jayant
Gibson, Philip W.
Ratto, Jo An
Samuelson, Lynne A.
TI Molecularly ordered structure and permeability properties of amphiphilic
polyacetylene-multilayer nanocomposites
SO COMPOSITES SCIENCE AND TECHNOLOGY
LA English
DT Article
DE Multilayer nanocomposites; Barrier membranes; Layer-by-layer assembly;
Ionic polyacetylenes
ID CONJUGATED IONIC POLYACETYLENES; LAYERED SILICATE NANOCOMPOSITES;
ALUMINOSILICATE NANOPLATELETS; POLYMERIZATION; SYSTEMS
AB Nanocomposite films consisting of. amphiphilic ionic polyacetylenes, (P2EPy-R) and layered aluminosilicates (saponite) have been prepared through electrostatic layer-by-layer assembly. The water vapor barrier properties of the nanocomposite films coated on Nafion (TM) film have been studied. The Nafion film coated with poly(N-octadecyl-2-ethynyloyridinium bromide) (P2EPy-C18) and aluminosilicates showed 22 times higher diffusion resistance to water vapor and 95% reduction in water vapor permeability when compared with the pristine Nafion control film. The X-ray diffraction data, UV-vis absorption spectroscopy, transmission electron microscopy (TEM), and atomic force microscopy (AFM) suggest a strong tendency of micellization of P2EPy-C18 polymer and ordered structure on the surface of aluminosilicate nanosheets compared to short alkyl side chains, C12, C6, and C0. The micellized and ordered structure of P2EPy-C18 between alummosilicate could explain the improved hydrophobic barrier properties of P2EPy-C18/aluminosilicate nanocomposites. (c) 2008 Elsevier Ltd. All rights reserved.
C1 [Kumar, Jayant] Univ Massachusetts, Dept Phys, Polymer Sci Plast Engn Program, Ctr Adv Mat, Lowell, MA 01854 USA.
[Ku, Bon-Cheol; Nagarajan, Ramaswamy; Blumstein, Alexandre] Univ Massachusetts, Dept Chem, Polymer Sci Plast Engn Program, Ctr Adv Mat, Lowell, MA 01854 USA.
[Kim, Dong Wook] Korea Res Inst Chem Technol, Adv Mat Div, Taejon 305600, South Korea.
[Steeves, Diane; Gibson, Philip W.; Ratto, Jo An; Samuelson, Lynne A.] USA, Natick Soldier Res Dev & Engn Ctr, Natick, MA 01760 USA.
RP Kumar, J (reprint author), Univ Massachusetts, Dept Phys, Polymer Sci Plast Engn Program, Ctr Adv Mat, Lowell, MA 01854 USA.
EM Jayant_Kumar@uml.edu
RI Gibson, Phillip/D-2398-2010;
OI Gibson, Phillip/0000-0002-6172-4438; KIM, DONG WOOK/0000-0002-0752-5366
FU US Army Natick Soldier Research, Development & Engineering Center
FX We acknowledge the financial support of US Army Natick Soldier Research,
Development & Engineering Center. The authors would like to thank M.
Downey and A. Jain for technical advice for X-ray diffraction and atomic
force microscopy.
NR 26
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U1 1
U2 7
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0266-3538
EI 1879-1050
J9 COMPOS SCI TECHNOL
JI Compos. Sci. Technol.
PD DEC
PY 2008
VL 68
IS 15-16
BP 3215
EP 3219
DI 10.1016/j.compscitech.2008.08.009
PG 5
WC Materials Science, Composites
SC Materials Science
GA 383JR
UT WOS:000261670400021
ER
PT J
AU Tezduyar, TE
Sathe, S
Pausewang, J
Schwaab, M
Christopher, J
Crabtree, J
AF Tezduyar, Tayfun E.
Sathe, Sunil
Pausewang, Jason
Schwaab, Matthew
Christopher, Jason
Crabtree, Jason
TI Interface projection techniques for fluid-structure interaction modeling
with moving-mesh methods
SO COMPUTATIONAL MECHANICS
LA English
DT Article; Proceedings Paper
CT Fluid-Structure Interaction Minisymposium
CY JUN 05-07, 2007
CL Barcelona, SPAIN
DE interface projection techniques; air-fabric interaction; fluid-structure
interaction; space-time FSI technique; sails; parachutes
ID FINITE-ELEMENT COMPUTATIONS; INCOMPRESSIBLE-FLOW COMPUTATIONS;
NAVIER-STOKES EQUATIONS; SPACE-TIME PROCEDURE; BOUNDARY FLOWS;
FORMULATION; PARACHUTE; SIMULATION; SYSTEMS; GEOMETRIES
AB The stabilized space-time fluid-structure interaction (SSTFSI) technique developed by the Team for Advanced Flow Simulation and Modeling (T*AFSM) was applied to a number of 3D examples, including arterial fluid mechanics and parachute aerodynamics. Here we focus on the interface projection techniques that were developed as supplementary methods targeting the computational challenges associated with the geometric complexities of the fluid-structure interface. Although these supplementary techniques were developed in conjunction with the SSTFSI method and in the context of air-fabric interactions, they can also be used in conjunction with other moving-mesh methods, such as the Arbitrary Lagrangian-Eulerian (ALE) method, and in the context of other classes of FSI applications. The supplementary techniques currently consist of using split nodal values for pressure at the edges of the fabric and incompatible meshes at the air-fabric interfaces, the FSI Geometric Smoothing Technique (FSI-GST), and the Homogenized Modeling of Geometric Porosity (HMGP). Using split nodal values for pressure at the edges and incompatible meshes at the interfaces stabilizes the structural response at the edges of the membrane used in modeling the fabric. With the FSI-GST, the fluid mechanics mesh is sheltered from the consequences of the geometric complexity of the structure. With the HMGP, we bypass the intractable complexities of the geometric porosity by approximating it with an "equivalent", locally-varying fabric porosity. As test cases demonstrating how the interface projection techniques work, we compute the air-fabric interactions of windsocks, sails and ringsail parachutes.
C1 [Tezduyar, Tayfun E.; Sathe, Sunil; Pausewang, Jason; Schwaab, Matthew; Christopher, Jason] Rice Univ, Houston, TX 77005 USA.
[Crabtree, Jason] US Mil Acad, West Point, NY 10996 USA.
RP Tezduyar, TE (reprint author), Rice Univ, MS 321,6100 Main St, Houston, TX 77005 USA.
EM tezduyar@rice.edu
RI Tezduyar, Tayfun/F-6134-2012
OI Tezduyar, Tayfun/0000-0001-8707-3162
NR 64
TC 86
Z9 86
U1 0
U2 10
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0178-7675
J9 COMPUT MECH
JI Comput. Mech.
PD DEC
PY 2008
VL 43
IS 1
BP 39
EP 49
DI 10.1007/s00466-008-0261-7
PG 11
WC Mathematics, Interdisciplinary Applications; Mechanics
SC Mathematics; Mechanics
GA 352RB
UT WOS:000259514000003
ER
PT J
AU Tezduyar, TE
Sathe, S
Schwaab, M
Pausewang, J
Christopher, J
Crabtree, J
AF Tezduyar, Tayfun E.
Sathe, Sunil
Schwaab, Matthew
Pausewang, Jason
Christopher, Jason
Crabtree, Jason
TI Fluid-structure interaction modeling of ringsail parachutes
SO COMPUTATIONAL MECHANICS
LA English
DT Article; Proceedings Paper
CT Fluid-Structure Interaction Minisymposium
CY JUN 05-07, 2007
CL Barcelona, SPAIN
DE ringsail parachute; orion space vehicle; fluid-structure interaction;
offloading; drifting
ID FINITE-ELEMENT COMPUTATIONS; INCOMPRESSIBLE-FLOW COMPUTATIONS;
NAVIER-STOKES EQUATIONS; MOVING BOUNDARY FLOWS; SPACE-TIME PROCEDURE;
FORMULATION; SIMULATION; INTERFACES; SYSTEMS; GEOMETRIES
AB In this paper, we focus on fluid-structure interaction (FSI) modeling of ringsail parachutes, where the geometric complexity created by the "rings" and "sails" used in the construction of the parachute canopy poses a significant computational challenge. It is expected that NASA will be using a cluster of three ringsail parachutes, referred to as the "mains", during the terminal descent of the Orion space vehicle. Our FSI modeling of ringsail parachutes is based on the stabilized space-time FSI (SSTFSI) technique and the interface projection techniques that address the computational challenges posed by the geometric complexities of the fluid-structure interface. Two of these interface projection techniques are the FSI Geometric Smoothing Technique and the Homogenized Modeling of Geometric Porosity. We describe the details of how we use these two supplementary techniques in FSI modeling of ringsail parachutes. In the simulations we report here, we consider a single main parachute, carrying one third of the total weight of the space vehicle. We present results from FSI modeling of offloading, which includes as a special case dropping the heat shield, and drifting under the influence of side winds.
C1 [Tezduyar, Tayfun E.; Sathe, Sunil; Schwaab, Matthew; Pausewang, Jason; Christopher, Jason] Rice Univ, Houston, TX 77005 USA.
[Crabtree, Jason] US Mil Acad W Point, New York, NY 10996 USA.
RP Tezduyar, TE (reprint author), Rice Univ, MS 321,6100 Main St, Houston, TX 77005 USA.
EM tezduyar@rice.edu
RI Tezduyar, Tayfun/F-6134-2012
OI Tezduyar, Tayfun/0000-0001-8707-3162
NR 63
TC 65
Z9 67
U1 0
U2 10
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0178-7675
J9 COMPUT MECH
JI Comput. Mech.
PD DEC
PY 2008
VL 43
IS 1
BP 133
EP 142
DI 10.1007/s00466-008-0260-8
PG 10
WC Mathematics, Interdisciplinary Applications; Mechanics
SC Mathematics; Mechanics
GA 352RB
UT WOS:000259514000012
ER
PT J
AU Thorp, KR
DeJonge, KC
Kaleita, AL
Batchelor, WD
Paz, JO
AF Thorp, Kelly R.
DeJonge, Kendall C.
Kaleita, Amy L.
Batchelor, William D.
Paz, Joel O.
TI Methodology for the use of DSSAT models for precision agriculture
decision support
SO COMPUTERS AND ELECTRONICS IN AGRICULTURE
LA English
DT Article
DE Precision farming; Crop models; Prescriptions; DSSAT; Decision support
system
ID INCREASING CARBON-DIOXIDE; OCEAN-ATMOSPHERE MODEL; TRANSIENT-RESPONSE;
YIELD VARIABILITY; MANAGEMENT; NITROGEN; CLIMATE; CORN; STRATEGIES;
SOYBEANS
AB A prototype decision support system (DSS) called Apollo was developed to assist researchers in using the Decision Support System for Agrotechnology Transfer (DSSAT) crop growth models to analyze precision farming datasets. Because the DSSAT models are written to simulate crop growth and development within a homogenous unit of land, the Apollo DSS has specialized functions to manage running the DSSAT models to simulate and analyze spatially variable land and management. The DSS has modules that allow the user to build model input files for spatial simulations across predefined management zones, calibrate the models to simulate historic spatial yield variability, validate the models for seasons not used for calibration, and estimate the crop response and environmental impacts of nitrogen, plant population, cultivar, and irrigation prescriptions. This paper details the functionality of Apollo, and presents the results of an example application. (C) 2008 Elsevier B.V. All rights reserved.
C1 [Kaleita, Amy L.] Iowa State Univ, Dept Agr & Biosyst Engn, Ames, IA 50011 USA.
[Thorp, Kelly R.] ARS, USDA, Maricopa, AZ USA.
[DeJonge, Kendall C.] USA, Corps Engineers, Omaha, NE USA.
[Batchelor, William D.] Mississippi State Univ, Mississippi State, MS 39762 USA.
[Paz, Joel O.] Univ Georgia, Griffin, GA USA.
RP Kaleita, AL (reprint author), Iowa State Univ, Dept Agr & Biosyst Engn, 211 Davidson Hall, Ames, IA 50011 USA.
EM kaleita@iastate.edu
RI Paz, Joel/F-7685-2010; Thorp, Kelly/C-2013-2009; Kaleita,
Amy/J-8363-2016;
OI Thorp, Kelly/0000-0001-9168-875X; Kaleita, Amy/0000-0002-8906-3408; Paz,
Joel/0000-0003-0193-3681
NR 22
TC 25
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U1 5
U2 32
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0168-1699
J9 COMPUT ELECTRON AGR
JI Comput. Electron. Agric.
PD DEC
PY 2008
VL 64
IS 2
BP 276
EP 285
DI 10.1016/j.compag.2008.05.022
PG 10
WC Agriculture, Multidisciplinary; Computer Science, Interdisciplinary
Applications
SC Agriculture; Computer Science
GA 374WN
UT WOS:000261074500020
ER
PT J
AU Dubick, MA
Scherer, MR
Darlington, DN
Delgado, AV
Martini, WZ
Kheirabadi, BS
AF Dubick, Michael A.
Scherer, Michael R.
Darlington, Daniel N.
Delgado, Angel V.
Martini, Wenjun Z.
Kheirabadi, Bijan S.
TI HEMOSTATIC EFFECTS OF RECOMBINANT ACTIVATED FACTOR VII (RFVIIA) IN
ACIDOTIC AND PH CORRECTED SWINE.
SO CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
CT 38th Critical Care Congress of the Society-of-Critical-Care-Medicine
CY JAN 31-FEB 04, 2009
CL Nashville, TN
SP Soc Crit Care Med
C1 [Dubick, Michael A.; Scherer, Michael R.; Darlington, Daniel N.; Delgado, Angel V.; Martini, Wenjun Z.; Kheirabadi, Bijan S.] USA, Inst Surg Res, San Antonio, TX USA.
NR 0
TC 0
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U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0090-3493
J9 CRIT CARE MED
JI Crit. Care Med.
PD DEC
PY 2008
VL 36
IS 12
SU S
MA 445
BP A110
EP A110
PG 1
WC Critical Care Medicine
SC General & Internal Medicine
GA 376WM
UT WOS:000261213700410
ER
PT J
AU Holt, DB
Delaney, RR
Hashim, G
Sato, A
Hernandez, C
Uyehara, CF
AF Holt, Danielle B.
Delaney, Richard R.
Hashim, Glenn
Sato, Aileen
Hernandez, Claudia
Uyehara, Catherine F.
TI ADRENAL INSUFFICIENCY MAY PREDICT NON-RESPONSIVENESS TO DOBUTAMINE
STRESS TEST IN SEPTIC SHOCK.
SO CRITICAL CARE MEDICINE
LA English
DT Meeting Abstract
CT 38th Critical Care Congress of the Society-of-Critical-Care-Medicine
CY JAN 31-FEB 04, 2009
CL Nashville, TN
SP Soc Crit Care Med
C1 [Holt, Danielle B.; Delaney, Richard R.; Hashim, Glenn; Sato, Aileen; Hernandez, Claudia; Uyehara, Catherine F.] Tripler Army Med Ctr, Honolulu, HI 96859 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0090-3493
J9 CRIT CARE MED
JI Crit. Care Med.
PD DEC
PY 2008
VL 36
IS 12
SU S
MA 176
BP A40
EP A40
PG 1
WC Critical Care Medicine
SC General & Internal Medicine
GA 376WM
UT WOS:000261213700144
ER
PT J
AU Logemann, JA
Rademaker, A
Pauloski, BR
Antinoja, J
Bacon, M
Bernstein, M
Gaziano, J
Grande, B
Kelchner, L
Kelly, A
Klaben, B
Lundy, D
Newman, L
Santa, D
Stachowiak, L
Stangl-McBreen, C
Atkinson, C
Bassani, H
Czapla, M
Farquharson, J
Larsen, K
Lewis, V
Logan, H
Nitschke, T
Veis, S
AF Logemann, Jeri A.
Rademaker, Alfred
Pauloski, Barbara Roa
Antinoja, Jodi
Bacon, Mary
Bernstein, Michelle
Gaziano, Joy
Grande, Barbara
Kelchner, Lisa
Kelly, Amy
Klaben, Bernice
Lundy, Donna
Newman, Lisa
Santa, Daphne
Stachowiak, Linda
Stangl-McBreen, Carrie
Atkinson, Cory
Bassani, Heidi
Czapla, Melissa
Farquharson, Julie
Larsen, Kristin
Lewis, Vicki
Logan, Heather
Nitschke, Teri
Veis, Sharon
TI What Information Do Clinicians Use in Recommending Oral versus Nonoral
Feeding in Oropharyngeal Dysphagic Patients?
SO DYSPHAGIA
LA English
DT Article
DE Oral feeding; Nonoral feeding; Videofluoroscopy; Oropharyngeal
dysphagia; Deglutition; Deglutition disorders
ID RELATIVE RISK; PNEUMONIA; ASPIRATION; STROKE
AB There is little evidence regarding the type(s) of information clinicians use to make the recommendation for oral or nonoral feeding in patients with oropharyngeal dysphagia. This study represents a first step toward identifying data used by clinicians to make this recommendation and how clinical experience may affect the recommendation. Thirteen variables were considered critical in making the oral vs. nonoral decision by the 23 clinicians working in dysphagia. These variables were then used by the clinicians to independently recommend oral vs. nonoral feeding or partial oral with nonoral feeding for the 20 anonymous patients whose modified barium swallows were sent on a videotape to each clinician. Clinicians also received data on the 13 variables for each patient. Results of clinician agreement on the recommendation of full oral and nonoral only were quite high, as measured by Kappa statistics. In an analysis of which of the 13 criteria clinicians used in making their recommendations, amount of aspiration was the criterion with the highest frequency. Recommendations for use of postures and maneuvers and the effect of clinician experience on these choices were also analyzed.
C1 [Logemann, Jeri A.; Pauloski, Barbara Roa] Northwestern Univ, Dept Commun Sci & Disorders, Evanston, IL 60208 USA.
[Rademaker, Alfred] Northwestern Univ, Dept Prevent Med, Robert H Lurie Comprehens Canc Ctr, Chicago, IL 60611 USA.
[Antinoja, Jodi] Froedtert Mem Lutheran Hosp, Milwaukee, WI 53226 USA.
[Bacon, Mary] Edward Hines Vet Adm Med Ctr, Hines, IL 60141 USA.
[Bernstein, Michelle; Lundy, Donna] Univ Miami, Hosp Med Ctr, Dept Otolaryngol, Miami, FL 33136 USA.
[Gaziano, Joy; Stachowiak, Linda; Czapla, Melissa; Lewis, Vicki] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL 33612 USA.
[Grande, Barbara] St Joseph Reg Med Ctr, Milwaukee, WI 53210 USA.
[Kelchner, Lisa] Univ Cincinnati, CAHS Commun Sci & Disorders, Cincinnati, OH 45267 USA.
[Kelly, Amy] Evanston NW Healthcare, Speech Pathol Dept, Evanston, IL 60201 USA.
[Klaben, Bernice] Blaine Block Inst Voice Anal & Rehabil, Dayton, OH 45402 USA.
[Newman, Lisa; Bassani, Heidi] Walter Reed Army Med Ctr, Army Audiol & Speech Ctr, Washington, DC 20307 USA.
[Santa, Daphne] Miami VA Med Ctr, Miami, FL 33125 USA.
[Stangl-McBreen, Carrie; Atkinson, Cory; Farquharson, Julie; Larsen, Kristin; Logan, Heather; Veis, Sharon] NW Mem Hosp, Chicago, IL 60611 USA.
[Nitschke, Teri] Zablocki Vet Adm Med Ctr, Milwaukee, WI 53295 USA.
RP Logemann, JA (reprint author), Northwestern Univ, Dept Commun Sci & Disorders, 2240 N Campus Dr,Room 3-358, Evanston, IL 60208 USA.
EM j-logemann@northwestern.edu
FU NCRR NIH HHS [UL1 RR031973]; NIDDK NIH HHS [R01 DK062178, R01
DK062178-03]
NR 11
TC 5
Z9 6
U1 1
U2 6
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0179-051X
J9 DYSPHAGIA
JI Dysphagia
PD DEC
PY 2008
VL 23
IS 4
BP 378
EP 384
DI 10.1007/s00455-008-9152-5
PG 7
WC Otorhinolaryngology
SC Otorhinolaryngology
GA 372YT
UT WOS:000260938900005
PM 18670808
ER
PT J
AU VanNimwegen, RE
Kretzer, J
Cully, JF
AF VanNimwegen, Ron E.
Kretzer, Justin
Cully, Jack F., Jr.
TI ECOSYSTEM ENGINEERING BY A COLONIAL MAMMAL: HOW PRAIRIE DOGS STRUCTURE
RODENT COMMUNITIES
SO ECOLOGY
LA English
DT Article
DE black-tailed prairie dogs; community composition; Cynomys spp.;
ecosystem engineer; nonmetric multidimensional scaling; ordination;
rodents; vegetation structure
ID BLACK-TAILED PRAIRIE; MIXED-GRASS PRAIRIE; SHORTGRASS-PRAIRIE;
SPECIES-DIVERSITY; ORGANISMS; LANDSCAPE
AB As ecosystem engineers, prairie dogs (Cynomys spp.) physically alter their environment, but the mechanism by which these alterations affect associated faunal composition is not well known. We examined how rodent and vegetation communities responded to prairie dog colonies and landcover at the Cimarron National Grassland in southwest Kansas, USA. We trapped rodents and measured vegetation structure on and off colonies in 2000 and 2003. We plotted two separate ordinations of trapping grids: one based on rodent counts and a second based on vegetation variables. We regressed three factors on each ordination: (1) colony (on-colony and off-colony), (2) cover (shortgrass and sandsage), and (3) habitat (factorial cross of colony X cover). Rodent communities differed by colony but not cover. Vegetation differed across both gradients. Rodent responses to habitat reflected those of colony and cover, but vegetation was found to differ across cover only in the sandsage prairie. This interaction suggested that rodent composition responded to prairie dog colonies, but independently of vegetation differences. We conclude that burrowing and soil disturbance are more important than vegetation cropping in structuring rodent communities.
C1 [VanNimwegen, Ron E.; Cully, Jack F., Jr.] Kansas State Univ, Div Biol, Manhattan, KS 66506 USA.
[Kretzer, Justin] ITAM, Ft Sill, OK 73503 USA.
[Cully, Jack F., Jr.] Kansas State Univ, US Geol Survey, Kansas Cooperat Fish & Wildlife Res Unit, Manhattan, KS 66506 USA.
RP VanNimwegen, RE (reprint author), Kansas State Univ, Div Biol, Ackert Hall, Manhattan, KS 66506 USA.
EM vanron@ksu.edu
FU U. S. Fish and Wildlife Service; U. S. Forest Service; Kansas
Cooperative Fish and Wildlife Research Unit; Division of Biology of
Kansas State University
FX Funding for this report was funded by the U. S. Fish and Wildlife
Service, U. S. Forest Service, Kansas Cooperative Fish and Wildlife
Research Unit, and the Division of Biology of Kansas State University.
E. Agner, P. Lemons, D. Martin, S. Meyers, M. Wong, J. Wertz, D.
Winslow, S. Winter, and B. Thiagarajan provided extensive field
assistance and data entry. P. Stapp, C. Paukert, and two anonymous
reviewers provided reviews and valuable comments.
NR 35
TC 22
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U1 6
U2 29
PU ECOLOGICAL SOC AMER
PI WASHINGTON
PA 1990 M STREET NW, STE 700, WASHINGTON, DC 20036 USA
SN 0012-9658
J9 ECOLOGY
JI Ecology
PD DEC
PY 2008
VL 89
IS 12
BP 3298
EP 3305
DI 10.1890/07-1511.1
PG 8
WC Ecology
SC Environmental Sciences & Ecology
GA 381GP
UT WOS:000261524000006
PM 19137937
ER
PT J
AU Veerappan, GR
Koff, JM
Smith, MT
AF Veerappan, G. R.
Koff, J. M.
Smith, M. T.
TI Enteryx polymer migration to lymph nodes and beyond
SO ENDOSCOPY
LA English
DT Editorial Material
C1 [Veerappan, G. R.; Koff, J. M.; Smith, M. T.] Walter Reed Army Med Ctr, Dept Med, Gastroenterol Serv, 6900 Georgia Ave, Washington, DC 20307 USA.
RP Veerappan, GR (reprint author), Walter Reed Army Med Ctr, Dept Med, Gastroenterol Serv, 6900 Georgia Ave, Washington, DC 20307 USA.
EM ganesh.veerappan@amedd.army.mil
NR 3
TC 1
Z9 1
U1 0
U2 0
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0013-726X
EI 1438-8812
J9 ENDOSCOPY
JI Endoscopy
PD DEC
PY 2008
VL 40
SU 2
BP E10
EP E11
DI 10.1055/s-2007-995391
PG 2
WC Gastroenterology & Hepatology; Surgery
SC Gastroenterology & Hepatology; Surgery
GA V42SV
UT WOS:000209634400006
PM 18278711
ER
PT J
AU Best, EPH
Tatem, HE
Geter, KN
Wells, ML
Lane, BK
AF Best, Elly P. H.
Tatem, Henry E.
Geter, Kaaren N.
Wells, Melissa L.
Lane, Brian K.
TI EFFECTS, UPTAKE, AND FATE OF 2,4,6-TRINITROTOLUENE AGED IN SOIL IN
PLANTS AND WORMS
SO ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
LA English
DT Article
DE 2,4,6-Trinitrotoluene; Aged; Bioavailability; Plants; Worms
ID ARMY AMMUNITION PLANT; SANDY LOAM SOIL; EISENIA-ANDREI; TNT; RDX;
PHYTOTOXICITY; EXPLOSIVES; TOXICITY
AB The present study was aimed at providing data to be used at predicting exposure-based effects of 2,4,6-trinitrotoluene (TNT) aged in soil on endpoint organisms representing two trophic levels. These data can be used to define criteria or reference values for environmental management and conducting specific risk assessment. Long-term exposure tests were conducted to evaluate sublethal toxicity and uptake of aged soil-based explosives, with TNT as the main contaminant. In these tests, plants were exposed for 55 d, and biomass and explosives residues were determined. Worms were exposed for 28 and 42 d, and biomass, number, and tissue residues were determined. Biomass of Lolium perenne significantly decreased with soil-TNT concentration, and an effective concentration causing a 20% decrease in biomass (EC20) for TNT metabolites of 3.75 mg/kg was calculated. The concentrations of TNT metabolites in shoots and roots were significantly related to concentrations in soil, as were concentrations of hexahydro-1,3,5-trinitro-1,3,5 triazine (RDX) and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX). The mean bioconcentration factors, indicating the potential of a chemical to accumulate in an organism, were 0.9 for TNT metabolites, 71.8 for RDX, and 12.2 for HMX in L. perenne shoots. Biomass of Eisenia fetida adults significantly decreased with soil-TNT concentration, and an EC20 for TNT of 3.70 mg/kg was calculated. The TNT, RDX, and HMX levels in E. fetida were below detection.
C1 [Best, Elly P. H.; Tatem, Henry E.; Wells, Melissa L.] USA, Engineer Res & Dev Ctr, Environm Lab, Vicksburg, MS 39180 USA.
[Geter, Kaaren N.] Analyt Serv, Vicksburg, MS 39180 USA.
RP Best, EPH (reprint author), USA, Engineer Res & Dev Ctr, Environm Lab, 3909 Halls Ferry Rd, Vicksburg, MS 39180 USA.
EM elly.p.best@erdc.usace.army.mil
FU U. S. Army Corps of Engineers Environmental Quality Technology Program;
Army Environmental Research and Development Center's Project
Bioavailability, Uptake, Toxicity; Transfer Across Trophic Levels of
TNT; RDX in Aged Soil; Margaret Richmond (Analytical Services)
FX This research was funded by the U. S. Army Corps of Engineers
Environmental Quality Technology Program. The present work was part of
the Army Environmental Research and Development Center's Project
Bioavailability, Uptake, Toxicity, and Transfer Across Trophic Levels of
TNT and RDX in Aged Soil. Margaret Richmond (Analytical Services)
provided partial technical
NR 33
TC 14
Z9 14
U1 0
U2 9
PU SETAC PRESS
PI PENSACOLA
PA 1010 N 12TH AVE, PENSACOLA, FL 32501-3367 USA
SN 0730-7268
J9 ENVIRON TOXICOL CHEM
JI Environ. Toxicol. Chem.
PD DEC
PY 2008
VL 27
IS 12
BP 2539
EP 2547
DI 10.1897/08-017.1
PG 9
WC Environmental Sciences; Toxicology
SC Environmental Sciences & Ecology; Toxicology
GA 393UQ
UT WOS:000262399300016
PM 18620472
ER
PT J
AU Best, EPH
Hintelmann, H
Dimock, B
Bednar, AJ
AF Best, Elly P. H.
Hintelmann, Holger
Dimock, Brian
Bednar, Anthony J.
TI Natural Cycles and Transfer of Mercury Through Pacific Coastal Marsh
Vegetation Dominated by Spartina foliosa and Salicornia virginica
SO ESTUARIES AND COASTS
LA English
DT Article
DE Mercury; Monomethylmercury; Salt marsh; Estuarine; Spartina; Salicornia
ID SAN-FRANCISCO-BAY; SALT-MARSH; FOOD-WEBS; PHRAGMITES-AUSTRALIS;
ALTERNIFLORA LOISEL; STABLE-ISOTOPES; DETRITUS; ESTUARY; WETLAND; PLANTS
AB The potential for marsh plants to be vectors in the transport of mercury species was studied in the natural, mature, tidal China Camp salt marsh on San Pablo Bay. The fluxes of organic matter, mercury (THg), and monomethylmercury (MeHg) were studied in natural stands of Spartina foliosa and Salicornia virginica. Seasonal fluxes from the sediment into aboveground biomass of live plants and subsequent transfer into the dead plant community by mortality were measured. Loss of THg and MeHg from the dead plant community through fragmentation, leaching, and excretion were calculated and were similar to net uptake. Seasonal data were added up to calculate annual mass balances. In S. foliosa, annual net production was 1,757 g DW m2, and the annual net uptakes in the aboveground biomass were 305 mu g THg m2 and 5.720 mu g MeHg m-2. In S. virginica, annual net production was 2,117 g DW m2, and the annual net uptakes in aboveground biomass were 99.120 mu g THg m-2 and 1.990 mu g MeHg m-2. Of both plant species studied, S. foliosa had a slightly lower production rate but greater mercury species uptake and loss rates than S. virginica, and, consequently, it is to be expected that S. foliosa matter may affect the local and possibly the regional food web relatively more than S. virginica. However, the actual effects of the input of mercury-species-containing plant-derived particulate matter into the food webs would depend on trophic level, food preference, seasonal cycle of the consumer, total sediment surface area vegetated, location of the vegetation in the marsh landscape, and estuary bay landscape. Since the levels of mercury species in dead plant material greatly exceed those in live plant material (on a dry weight basis), detritivores would ingest greater mercury species concentrations than herbivores, and consumers of S. foliosa would ingest more than consumers of S. virginica. The greatest THg and MeHg losses of both plant species due to mortality and to fragmentation-leaching-excretion occurred in late spring and early autumn, which corresponds to peak MeHg levels observed in sediments of coastal systems of previous studies, suggesting enhanced THg-MeHg export from the marsh to the nearshore sediment.
C1 [Best, Elly P. H.; Bednar, Anthony J.] USA, Engineer Res & Dev Ctr, Environm Lab, Vicksburg, MS 39180 USA.
[Hintelmann, Holger; Dimock, Brian] Trent Univ, Dept Chem, Peterborough, ON K9J 7B8, Canada.
RP Best, EPH (reprint author), USA, Engineer Res & Dev Ctr, Environm Lab, Vicksburg, MS 39180 USA.
EM elly.p.best@usace.army.mil
OI Hintelmann, Holger/0000-0002-5287-483X
FU Long-Term Management Strategy; US Army Corps of Engineers (USACE)
FX This research was supported by the Long-Term Management Strategy,
administered by the US Army Corps of Engineers (USACE) San Francisco
District, awarded for the project "Transfer of mercury from primary
producers to consumers-quantifying the entry of mercury into the aquatic
food web" to E. P. H. Best. Best has full control of all primary data
and agrees to allow the journal to review the data if requested. No
potential conflict of interest exists.
NR 58
TC 4
Z9 5
U1 2
U2 18
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1559-2723
J9 ESTUAR COAST
JI Estuaries Coasts
PD DEC
PY 2008
VL 31
IS 6
BP 1072
EP 1088
DI 10.1007/s12237-008-9086-z
PG 17
WC Environmental Sciences; Marine & Freshwater Biology
SC Environmental Sciences & Ecology; Marine & Freshwater Biology
GA 369IA
UT WOS:000260686700005
ER
PT J
AU Webb, HE
Weldy, ML
Fabianke-Kadue, EC
Orndorff, GR
Kamimori, GH
Acevedo, EO
AF Webb, Heather E.
Weldy, Michael L.
Fabianke-Kadue, Emily C.
Orndorff, G. R.
Kamimori, Gary H.
Acevedo, Edmund O.
TI Psychological stress during exercise: cardiorespiratory and hormonal
responses
SO EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
LA English
DT Article
DE Exercise; physiology; Exercise; psychology; Mental processes;
physiology; Stress; psychological; physiopathology
ID MENTAL STRESS; AEROBIC EXERCISE; PLASMA; CHALLENGE; INTENSITY;
INCREASES; BLOOD
AB The purpose of this study was to examine the cardiorespiratory (CR) and stress hormone responses to a combined physical and mental stress. Eight participants with participants responding to a computerized mental challenge dual stress condition (DSC) and a control condition of the same duration and intensity without the mental challenge exercise alone condition (EAC). Significant interactions across time were found for CR responses, with heart rate, ventilation, and respiration rate demonstrating higher increases in the DSC. Additionally, norepinephrine was significantly greater in the DSC at the end of the combined challenge. Furthermore, cortisol area-under-the-curve (AUC) was also significantly elevated during the DSC. These results demonstrate that a mental challenge during exercise can exacerbate the stress response, including the release of hormones that have been linked to negative health consequences (cardiovascular, metabolic, autoimmune illnesses).
C1 [Webb, Heather E.] Mississippi State Univ, Dept Kinesiol, Mississippi State, MS 39762 USA.
[Weldy, Michael L.; Fabianke-Kadue, Emily C.; Orndorff, G. R.] Univ Mississippi, Dept Hlth Exercise Sci & Recreat Management, Oxford, MS USA.
[Kamimori, Gary H.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Acevedo, Edmund O.] Virginia Commonwealth Univ, Dept Hlth & Human Performance, Richmond, VA USA.
RP Webb, HE (reprint author), Mississippi State Univ, Dept Kinesiol, 121 McCarthy Gymnasium, Mississippi State, MS 39762 USA.
EM hwebb@colled.msstate.edu
RI Webb, Heather/A-4219-2010
OI Webb, Heather/0000-0002-3925-9613
NR 33
TC 19
Z9 19
U1 3
U2 7
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1439-6319
J9 EUR J APPL PHYSIOL
JI Eur. J. Appl. Physiol.
PD DEC
PY 2008
VL 104
IS 6
BP 973
EP 981
DI 10.1007/s00421-008-0852-1
PG 9
WC Physiology; Sport Sciences
SC Physiology; Sport Sciences
GA 368QB
UT WOS:000260636500004
PM 18762969
ER
PT J
AU Kenefick, RW
St Pierre, A
Riel, NA
Cheuvront, SN
Castellani, JW
AF Kenefick, Robert William
St Pierre, A.
Riel, N. A.
Cheuvront, S. N.
Castellani, J. W.
TI Effect of increased plasma osmolality on cold-induced thirst attenuation
SO EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
LA English
DT Article
DE Dehydration; Thirst; NaCl load; Cold exposure
ID VASOPRESSIN RELEASE; OSMOTIC THIRST; DEHYDRATION; EXERCISE;
HYPOHYDRATION; DRINKING; HUMANS; THERMOREGULATION; TEMPERATURE;
STIMULATION
AB The effects of elevating plasma osmolality (P (osm)) on thirst ratings was studied in eight dehydrated males during exposure to 4C. On two occasions, subjects were dehydrated (DH; 3-4% body mass) via 90 min exercise-heat exposure and overnight fluid restriction (day 1). On a third occasion, subjects were exposed to heat but were given fluid (EU). On day 2, subjects consumed NaCl (NaCl; 0.1 g NaCl kg-1 body mass in 500 ml H(2)O; DH only) or Placebo (P; 500 ml H(2)O; DH and EU). Subjects stood for 30 min at 24C and for 45 min at 4C (75 min post-dose). P (osm) was elevated (P < 0.05) 30 and 75 min after NaCl administration in DH + NaCl versus DH + P and EU + P treatments. Thirst ratings remained elevated (P < 0.05) in the DH + NaCl treatment 30 min after dosing and 45 min at 4C versus DH + P and EU + P. Attenuation of thirst when dehydrated in the cold can be over-ridden by increasing P (osm).
C1 [Kenefick, Robert William; Cheuvront, S. N.; Castellani, J. W.] USA, Environm Med Res Inst, Thermal & Mt Med Div, Natick, MA 01760 USA.
[St Pierre, A.; Riel, N. A.] Univ New Hampshire, Dept Kinesiol, Durham, NH 03824 USA.
RP Kenefick, RW (reprint author), USA, Environm Med Res Inst, Thermal & Mt Med Div, Kansas St, Natick, MA 01760 USA.
EM Robert.Kenefick@us.army.mil
OI van Riel, Natal/0000-0001-9375-4730
NR 27
TC 2
Z9 2
U1 0
U2 4
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1439-6319
J9 EUR J APPL PHYSIOL
JI Eur. J. Appl. Physiol.
PD DEC
PY 2008
VL 104
IS 6
BP 1013
EP 1019
DI 10.1007/s00421-008-0857-9
PG 7
WC Physiology; Sport Sciences
SC Physiology; Sport Sciences
GA 368QB
UT WOS:000260636500009
PM 18758804
ER
PT J
AU Kunz, AN
Englund, JA
Kuypers, J
Maranich, A
Fairchok, MP
AF Kunz, A. N.
Englund, J. A.
Kuypers, J.
Maranich, A.
Fairchok, M. P.
TI Detection of multiple respiratory viruses by real-time polymerase chain
reaction in infants attending an outpatient clinic
SO EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
LA English
DT Editorial Material
ID YOUNG-CHILDREN; TRACT DISEASE; PCR ASSAYS; CORONAVIRUS
C1 [Kunz, A. N.] Walter Reed Army Med Ctr, Dept Pediat, Washington, DC 20307 USA.
[Kuypers, J.] Univ Washington, Dept Lab Med, Seattle, WA 98105 USA.
[Englund, J. A.; Fairchok, M. P.] Univ Washington, Childrens Hosp & Reg Med Ctr, Seattle, WA 98105 USA.
[Kunz, A. N.; Maranich, A.; Fairchok, M. P.] Madigan Army Med Ctr, Dept Pediat, Tacoma, WA 98431 USA.
RP Kunz, AN (reprint author), Walter Reed Army Med Ctr, Dept Pediat, Washington, DC 20307 USA.
EM kdocs2002@verizon.net
NR 9
TC 5
Z9 5
U1 0
U2 0
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0934-9723
J9 EUR J CLIN MICROBIOL
JI Eur. J. Clin. Microbiol. Infect. Dis.
PD DEC
PY 2008
VL 27
IS 12
BP 1245
EP 1248
DI 10.1007/s10096-008-0558-7
PG 4
WC Infectious Diseases; Microbiology
SC Infectious Diseases; Microbiology
GA 373EB
UT WOS:000260952700014
PM 18560910
ER
PT J
AU Blakely, JN
Corron, J
AF Blakely, J. N.
Corron, J.
TI Time shifting chaotic signals using synchronization
SO EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS
LA English
DT Article; Proceedings Paper
CT Conference on Chaos and Nonlinear Dynamics
CY 2007
CL Univ Aberdeen, Aberdeen, SCOTLAND
HO Univ Aberdeen
ID LAG SYNCHRONIZATION; OSCILLATOR ARRAYS; PHASE
AB In this paper we examine couplings that produce time-shifted synchronization. We find a surprising variety of time-shifted states can be attained without including an explicit time-delay term in the coupling. We characterize the observed synchronization by determining the dependence of the time shift and cross correlation between the drive and response oscillators on a tunable parameter. Our observations agree well with a recently introduced method for estimating the time shift and cross correlation using a transfer function.
C1 [Blakely, J. N.; Corron, J.] USA, RDECOM, AMSRD AMR WS ST, Redstone Arsenal, AL 35898 USA.
RP Blakely, JN (reprint author), USA, RDECOM, AMSRD AMR WS ST, Redstone Arsenal, AL 35898 USA.
EM jonathan.blakely@us.army.mil; ned.corron@us.army.mil
OI Blakely, Jonathan/0000-0002-9772-582X; Corron, Ned/0000-0002-3232-5024
NR 13
TC 2
Z9 2
U1 0
U2 0
PU EDP SCIENCES S A
PI LES ULIS CEDEX A
PA 17, AVE DU HOGGAR, PA COURTABOEUF, BP 112, F-91944 LES ULIS CEDEX A,
FRANCE
SN 1951-6355
J9 EUR PHYS J-SPEC TOP
JI Eur. Phys. J.-Spec. Top.
PD DEC
PY 2008
VL 165
BP 111
EP 117
DI 10.1140/epjst/e2008-00854-0
PG 7
WC Physics, Multidisciplinary
SC Physics
GA 383UC
UT WOS:000261698100012
ER
PT J
AU Oudkerk, M
Stillman, AE
Halliburton, SS
Kalender, WA
Mohlenkamp, S
McCollough, CH
Vliegenthart, R
Shaw, LJ
Stanford, W
Taylor, AJ
van Ooijen, PMA
Wexler, L
Raggi, P
AF Oudkerk, Matthijs
Stillman, Arthur E.
Halliburton, Sandra S.
Kalender, Willi A.
Moehlenkamp, Stefan
McCollough, Cynthia H.
Vliegenthart, Rozemarijn
Shaw, Leslee J.
Stanford, William
Taylor, Allen J.
van Ooijen, Peter M. A.
Wexler, Lewis
Raggi, Paolo
TI Coronary artery calcium screening: current status and recommendations
from the European Society of Cardiac Radiology and North American
Society for Cardiovascular Imaging
SO EUROPEAN RADIOLOGY
LA English
DT Review
DE Coronary artery calcium; Coronary artery atherosclerosis; Coronary risk
assessment; Coronary artery CT
ID BEAM COMPUTED-TOMOGRAPHY; ALL-CAUSE MORTALITY; HEART-DISEASE EVENTS;
STAGE RENAL-DISEASE; ACUTE MYOCARDIAL-INFARCTION; EXPERT CONSENSUS
DOCUMENT; LIPID-LOWERING THERAPY; ACUTE CHEST-PAIN; RISK-FACTORS;
PROGNOSTIC VALUE
AB Current guidelines and literature on screening for coronary artery calcium for cardiac risk assessment are reviewed for both general and special populations. It is shown that for both general and special populations a zero score excludes most clinically relevant coronary artery disease. The importance of standardization of coronary artery calcium measurements by multidetector CT is discussed.
C1 [Oudkerk, Matthijs; Vliegenthart, Rozemarijn; van Ooijen, Peter M. A.] Univ Groningen Hosp, Dept Radiol, NL-9700 RB Groningen, Netherlands.
[Stillman, Arthur E.; Shaw, Leslee J.; Raggi, Paolo] Emory Univ, Dept Radiol, Atlanta, GA 30322 USA.
[Stillman, Arthur E.; Shaw, Leslee J.; Raggi, Paolo] Emory Univ, Dept Cardiol, Atlanta, GA 30322 USA.
[Halliburton, Sandra S.] Cleveland Clin Fdn, Imaging Inst, Cardiovasc Imaging Lab, Cleveland, OH 44195 USA.
[Kalender, Willi A.] Univ Erlangen Nurnberg, Inst Med Phys, Nurnberg, Germany.
[Moehlenkamp, Stefan] Univ Duisburg Essen, W German Heart Ctr Essen, Essen, Germany.
[McCollough, Cynthia H.] Mayo Clin, Dept Radiol, Rochester, MN USA.
[Stanford, William] Univ Iowa, Dept Radiol, Iowa City, IA 52242 USA.
[Taylor, Allen J.] Walter Reed Army Med Ctr, Div Cardiol, Washington, DC 20307 USA.
[Wexler, Lewis] Stanford Univ, Sch Med, Dept Radiol, Stanford, CA 94305 USA.
RP van Ooijen, PMA (reprint author), Univ Groningen Hosp, Dept Radiol, Hanzepl 1, NL-9700 RB Groningen, Netherlands.
EM p.m.a.van.ooyen@rad.azg.nl
RI van Ooijen, Peter/G-1146-2012; van Ooijen, Peter/B-9150-2008
OI van Ooijen, Peter/0000-0002-8995-1210; van Ooijen,
Peter/0000-0002-8995-1210
NR 142
TC 56
Z9 57
U1 0
U2 3
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0938-7994
J9 EUR RADIOL
JI Eur. Radiol.
PD DEC
PY 2008
VL 18
IS 12
BP 2785
EP 2807
DI 10.1007/s00330-008-1095-6
PG 23
WC Radiology, Nuclear Medicine & Medical Imaging
SC Radiology, Nuclear Medicine & Medical Imaging
GA 371NF
UT WOS:000260837300012
PM 18651153
ER
PT J
AU Jeka, JJ
Oie, KS
Kiemel, T
AF Jeka, John J.
Oie, Kelvin S.
Kiemel, Tim
TI Asymmetric adaptation with functional advantage in human sensorimotor
control
SO EXPERIMENTAL BRAIN RESEARCH
LA English
DT Article
DE Sensory re-weighting; Multisensory fusion; Vision; Adaptive control;
Posture
ID HUMAN POSTURAL CONTROL; MULTISENSORY INTEGRATION; SENSORY INTEGRATION;
VISUAL ENVIRONMENT; SWAY; INFORMATION; DYNAMICS; VISION; STANCE; ADULTS
AB Human movement control is inherently stochastic, requiring continuous estimation of self-motion based upon noisy sensory inputs. The nervous system must determine which sensory signals are relevant on a time scale that enables successful behavior. In human stance control, failure to effectively adapt to changing sensory contexts could lead to injurious falls. Nonlinear changes in postural sway amplitude in response to changes in sensory environmental motion have indicated a dynamic changing of the weighting of the nervous system's multiple sensory inputs so that estimates are based upon the most relevant and accurate information available. However, the time scale of these changes is virtually unknown. Results here show systematic changes in postural gain when visual scene motion amplitude is increased or decreased abruptly, consistent with sensory re-weighting. However, this re-weighting displayed a temporal asymmetry. When visual motion increased, gain decreased within 5 s to a value near its asymptotic value. In contrast, when visual motion decreased, it took an additional 5 s for gain to increase by a similar absolute amount. Suddenly increasing visual motion amplitude threatens balance if gain remains high, and rapid down-weighting of the sensory signal is required to avoid falling. By contrast, slow up-weighting suggests a conservative CNS strategy. It may not be functional to rapidly up-weight with transient changes in the sensory environment. Only sustained changes necessitate the slower up-weighting process. Such results add to our understanding of adaptive processing, identifying a temporal asymmetry in sensory re-weighting dynamics that could be a general property of adaptive estimation in the nervous system.
C1 [Jeka, John J.; Oie, Kelvin S.; Kiemel, Tim] Univ Maryland, Dept Kinesiol, College Pk, MD 20742 USA.
[Jeka, John J.; Oie, Kelvin S.] Univ Maryland, Neurosci & Cognit Sci Program, College Pk, MD 20742 USA.
[Jeka, John J.] Univ Maryland, Bioengn Grad Program, College Pk, MD 20742 USA.
[Oie, Kelvin S.] USA, Res Lab, Human Res & Engn Directorate, Aberdeen Proving Ground, MD 21005 USA.
RP Jeka, JJ (reprint author), Univ Maryland, Dept Kinesiol, College Pk, MD 20742 USA.
EM jjeka@umd.edu
FU National Institutes of Health [NIH 2RO1NS35070, 1RO1NS046065]
FX We would like to thank Dr. Jose Barela at the Universidade Estadual
Paulista in Rio Claro, Brazil for fruitful discussions of data on
reweighting dynamics acquired in his laboratory. Kelvin S Oie is
currently with the U. S. Army Research Laboratory, Human Research and
Engineering Directorate, Aberdeen Proving Ground, MD 21005. These
results were presented in preliminary form at the 17th meeting of the
International Society of Posture and Gait, Marseille, France ( Oie et
al. 2005). Funding for this research was provided by National Institutes
of Health grants NIH 2RO1NS35070 and 1RO1NS046065, John J. Jeka, P. I.
NR 42
TC 26
Z9 27
U1 1
U2 7
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0014-4819
J9 EXP BRAIN RES
JI Exp. Brain Res.
PD DEC
PY 2008
VL 191
IS 4
BP 453
EP 463
DI 10.1007/s00221-008-1539-x
PG 11
WC Neurosciences
SC Neurosciences & Neurology
GA 366GV
UT WOS:000260469600006
PM 18719898
ER
PT J
AU Mallozzi, M
Bozue, J
Giorno, R
Moody, KS
Slack, A
Cote, C
Qiu, DL
Wang, R
McKenney, P
Lai, EM
Maddock, JR
Friedlander, A
Welkos, S
Eichenberger, P
Driks, A
AF Mallozzi, Michael
Bozue, Joel
Giorno, Rebecca
Moody, Krishna-Sulayman
Slack, Alex
Cote, Christopher
Qiu, Dengli
Wang, Rong
McKenney, Peter
Lai, Erh-Min
Maddock, Janine R.
Friedlander, Arthur
Welkos, Susan
Eichenberger, Patrick
Driks, Adam
TI Characterization of a Bacillus anthracis spore coat-surface protein that
influences coat-surface morphology
SO FEMS MICROBIOLOGY LETTERS
LA English
DT Article
DE Bacillus anthracis; coat; germination; spore assembly; anthrax
ID STRUCTURAL DYNAMICS; BACTERIAL-SPORES; SUBTILIS SPORES; GENE-EXPRESSION;
MORPHOGENESIS; SPORULATION; RESISTANCE; VIRULENCE; COTE
AB Bacterial spores are encased in a multilayered proteinaceous shell, called the coat. In many Bacillus spp., the coat protects against environmental assault and facilitates germination. In Bacillus anthracis, the spore is the etiological agent of anthrax, and the functions of the coat likely contribute to virulence. Here, we characterize a B. anthracis spore protein, called Cot beta, which is encoded only in the genomes of the Bacillus cereus group. We found that Cot beta is synthesized specifically during sporulation and is assembled onto the spore coat surface. Our analysis of a cot beta null mutant in the Sterne strain reveals that Cot beta has a role in determining coat-surface morphology but does not detectably affect germination. In the fully virulent Ames strain, a cot beta null mutation has no effect on virulence in a murine model of B. anthracis infection.
C1 [Mallozzi, Michael; Giorno, Rebecca; Slack, Alex; Driks, Adam] Loyola Univ, Med Ctr, Dept Microbiol & Immunol, Maywood, IL 60153 USA.
[Bozue, Joel; Moody, Krishna-Sulayman; Cote, Christopher; Welkos, Susan] USA, Med Res Inst Infect Dis, Bacteriol Div, Frederick, MD USA.
[Qiu, Dengli; Wang, Rong] IIT, Dept Biol Chem & Phys Sci, Chicago, IL 60616 USA.
[McKenney, Peter; Eichenberger, Patrick] NYU, Dept Biol, New York, NY 10003 USA.
[McKenney, Peter; Eichenberger, Patrick] NYU, Ctr Genom & Syst Biol, New York, NY 10003 USA.
[Lai, Erh-Min] Acad Sinica, Inst Plant & Microbial Biol, Taipei 115, Taiwan.
[Maddock, Janine R.] Univ Michigan, Dept Mol Cellular & Dev Biol, Ann Arbor, MI USA.
[Friedlander, Arthur] USA, Med Res Inst Infect Dis, Frederick, MD USA.
RP Driks, A (reprint author), Loyola Univ, Med Ctr, Dept Microbiol & Immunol, 2160 S 1st Ave,Bldg 105,Rm 3820, Maywood, IL 60153 USA.
EM adriks@lumc.edu
FU National Institutes of Health (NIH) [GM53989, AI53365]; Department of
the Army [W81XWH-0401-0307]; United States Army Medical Research and
Materiel Command [02-4-5C018, 02-4-5C-023, 04-0-IL-002]
FX This work was supported by grants GM53989 and AI53365 from the National
Institutes of Health (NIH) (A. D.), Department of the Army Award Number
W81XWH-0401-0307 (P.E.), and the United States Army Medical Research and
Materiel Command under Projects 02-4-5C018 (J.A.B.), 02-4-5C-023 (S.W.)
and 04-0-IL-002 (S.W.). Research was onducted in compliance with the
Animal Welfare Act, and other federal statutes and regulations relating
to animals and experiments involving animals, and adheres to principles
stated in the Guide for the Care and Use of Laboratory Animals, National
Research Council, 1996. The facility where this research was conducted
is fully accredited by the Association for Assessment and Accreditation
of Laboratory Animal Care International. Opinions, interpretations,
conclusions, and recommendations are those of the author and are not
necessarily endorsed by the United States Army. We thank the Michigan
Proteome Consortium for the identification of Cotb.
NR 42
TC 11
Z9 11
U1 0
U2 7
PU WILEY-BLACKWELL
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 0378-1097
J9 FEMS MICROBIOL LETT
JI FEMS Microbiol. Lett.
PD DEC
PY 2008
VL 289
IS 1
BP 110
EP 117
DI 10.1111/j.1574-6968.2008.01380.x
PG 8
WC Microbiology
SC Microbiology
GA 362GJ
UT WOS:000260185900016
PM 19054101
ER
PT J
AU Levens, ED
Whitcom, BW
Hennessy, S
James, AN
Yauger, BJ
Larsen, FW
AF Levens, Eric D.
Whitcom, Brian W.
Hennessy, Sasha
James, Aidita N.
Yauger, Belinda J.
Larsen, Frederick W.
TI Blastocyst development rate impacts outcome in cryopreserved blastocyst
transfer cycles
SO FERTILITY AND STERILITY
LA English
DT Article
DE Frozen-thawed blastocyst cycle; embryo transfer; day 5 versus day 6
ID IN-VITRO FERTILIZATION; EMBRYO-TRANSFER; PREGNANCY RATES; CULTURE;
DAY-5; SUCCESS; IMPLANTATION; NUMBER
AB Objective: To assess cycle outcome among day 5 and day 6 cryopreserved frozen-thawed blastocyst embryo transfers (FBET).
Design: Retrospective cohort study.
Setting: Military-based assisted reproduction technology (ART) center.
Patient(s): One hundred seventy-two nondonor, programmed cryopreserved embryo cycles.
Intervention(s): Fully expanded blastocysts on day 5 were cryopreserved on day 5, and those achieving this state on day 6 were cryopreserved on day 6. Leuprolide acetate was given for ovulation inhibition, and endometrial supplementation was by oral and vaginal estradiol. Progesterone in oil was administered, and blastocyst transfer occurred in the morning of the sixth day of progesterone.
Main Outcome Measure(s): Implantation, pregnancy, and live-birth rates.
Result(s): Fresh and frozen cycle characteristics were similar between groups. Day-5 FBET had statistically significantly higher implantation rates (32.2% vs. 19.2%), which remained significant even when adjusting for covariates (odds ratio: 1.91; 95% confidence interval, 1.00, 3.67). Live-birth rates trended toward improvement after adjusting for covariates (odds ratio: 1.18; 95% confidence interval, 0.61, 2.30).
Conclusion(s): Cryopreserved day-5 blastocysts have higher implantation rates and trend toward improved pregnancy outcomes compared with cryopreserved day-6 blastocysts. This suggests that embryo development rate may, in part, predict implantation and subsequent FBET outcomes, although embryos not achieving the blastocyst stage until day 6 still demonstrate acceptable outcomes. (Fertil Steril(R) 2008;90:2138-43. (C) 2008 by American Society for Reproductive Medicine.)
C1 [Levens, Eric D.; Yauger, Belinda J.] NICHHD, Reprod Biol & Med Branch, NIH, Bethesda, MD 20892 USA.
[Whitcom, Brian W.] NICHHD, Epidemiol Branch, NIH, Bethesda, MD 20892 USA.
[Levens, Eric D.; Yauger, Belinda J.; Larsen, Frederick W.] Walter Reed Army Med Ctr, ART Program, Washington, DC 20307 USA.
[Levens, Eric D.; Yauger, Belinda J.; Larsen, Frederick W.] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
[Levens, Eric D.; Yauger, Belinda J.; Larsen, Frederick W.] NIH, Combined Fed Fellowship Program Reprod Endocrinol, Walter Reed Army Med Ctr, Natl Naval Med Ctr, Bethesda, MD 20892 USA.
[Hennessy, Sasha; James, Aidita N.] Wasington Inc, ART Inst, Washington, DC USA.
RP Levens, ED (reprint author), NICHHD, Reprod Biol & Med Branch, NIH, Bldg 10,CRC,Room E1-3140,10 Ctr Dr, Bethesda, MD 20892 USA.
EM levense@mail.nih.gov
FU Reproductive Biology and Medicine Branch, NICHD, NIH, Bethesda, MD
FX Research supported, in part, by the Reproductive Biology and Medicine
Branch, NICHD, NIH, Bethesda, MD. The opinions or assertions contained
herein are the private views of the authors and are not to be construed
as official or as reflecting the views of the Department of Health and
Human Services, the Department of the Army or the Department of Defense.
NR 19
TC 18
Z9 18
U1 0
U2 1
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0015-0282
J9 FERTIL STERIL
JI Fertil. Steril.
PD DEC
PY 2008
VL 90
IS 6
BP 2138
EP 2143
DI 10.1016/j.fertnstert.2007.10.029
PG 6
WC Obstetrics & Gynecology; Reproductive Biology
SC Obstetrics & Gynecology; Reproductive Biology
GA 381WO
UT WOS:000261566800015
PM 18178191
ER
PT J
AU Sun, WJ
Stegmann, BJ
Henne, M
Cwherino, WH
Segars, JH
AF Sun, Wenjie
Stegmann, Barbara J.
Henne, Melinda
Cwherino, Williain H.
Segars, James H.
TI A new approach to ovarian reserve testing
SO FERTILITY AND STERILITY
LA English
DT Article
DE Ovarian reserve; ovarian insufficiency; FSH; CC challenge test; inhibin;
diminished ovarian reserve; assisted reproduction; in vitro
fertilization (IVF); assisted reproductive technologies (ART)
ID IN-VITRO FERTILIZATION; FOLLICLE-STIMULATING-HORMONE; ASSISTED
REPRODUCTIVE TECHNOLOGY; CITRATE CHALLENGE TEST; RECURRENT PREGNANCY
LOSS; ANTI-MULLERIAN HORMONE; INHIBIN-B; PREDICTIVE-VALUE;
DOWNS-SYNDROME; BASAL MARKERS
AB Objective: To critically examine ovarian reserve testing before assisted reproduction.
Design: A PUBMED computer search to identify relevant literature.
Setting: Multiple sites.
Patient(s): Patients undergoing assisted reproduction.
Intervention(S): Testing for ovarian reserve.
Main Outcome Measure(S): Assisted reproductive technology (ART) and pregnancy outcomes.
Result(S): The prevalence of ovarian insufficiency varies significantly for women aged 30-45 years. Gerieralization or averaging of threshold values across different aged women leads to very poor sensitivity, specificity, and positive predictive value for all tests of ovarian reserve. Because of the changing prevalence of ovarian insufficiency, there is no single, suitable threshold value for any screening test of ovarian reserve. Our analysis supports dividing impaired ovarian reserve into two groups: age-dependent ovarian aging (physiologic) and premature (non-physiologic) reductions in the oocyte pool. Interpretation of any screening test used requires that age is considered as a variable. To guide clinical interpretation of test results, We suggest using a nomogram of FSH values versus expected delivery rate-per-cycle-start with ART for a given age.
Conclusion(s): Proper interpretation of screening tests for ovarian insufficiency in couples considering ART is important as the presence of impaired ovarian reserve is associated with a low likelihood of pregnancy. The condition of premature (nonphysiologic) ovarian insufficiency warrants additional research. (Fertil Steril(R) 2008;90:2196202. (C)2008 by American Society for Reproductive Medicine.)
C1 [Stegmann, Barbara J.; Segars, James H.] NICHHD, Reprod Biol & Med Branch, Bethesda, MD 20892 USA.
[Sun, Wenjie] Wake Forest Univ, Baptist Med Ctr, Dept Obstet & Gynecol, Winston Salem, NC 27109 USA.
[Stegmann, Barbara J.; Henne, Melinda; Cwherino, Williain H.; Segars, James H.] Walter Reed Army Med Ctr, Walter Reed ART Program, Washington, DC 20307 USA.
[Cwherino, Williain H.; Segars, James H.] Uniformed Serv Univ Hlth Sci, Dept Obstet & Gynecol, Bethesda, MD 20814 USA.
RP Segars, JH (reprint author), NICHD, RBMB, NIH, Bldg 10,CRC,Room 1E-3140,MSC 1109,10 Ctr Dr, Bethesda, MD 20892 USA.
EM segarsj@mail.nih.gov
FU Reproductive Biology and Medicine Branch of National Institute of Child
Health and Human Development, National Institutes of Health
FX Supported, in part, by the Reproductive Biology and Medicine Branch of
National Institute of Child Health and Human Development, National
Institutes of Health.
NR 44
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Z9 28
U1 0
U2 6
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0015-0282
J9 FERTIL STERIL
JI Fertil. Steril.
PD DEC
PY 2008
VL 90
IS 6
BP 2196
EP 2202
DI 10.1016/j.fertnstert.2007.10.080
PG 7
WC Obstetrics & Gynecology; Reproductive Biology
SC Obstetrics & Gynecology; Reproductive Biology
GA 381WO
UT WOS:000261566800023
PM 18433750
ER
PT J
AU Hamilton, CA
Maxwell, GL
Chemofsky, MR
Bernstein, SA
Farley, JH
Rose, GS
AF Hamilton, Chad A.
Maxwell, G. Larry
Chemofsky, Mildred R.
Bernstein, Sarah A.
Farley, John H.
Rose, G. Scott
TI Intraperitoneal bevacizumab for the palliation of malignant ascites in
refractory ovarian cancer
SO GYNECOLOGIC ONCOLOGY
LA English
DT Article
DE Bevacizumab; Intraperitoneal; Ovarian cancer; Ascites; Palliation
ID ENDOTHELIAL GROWTH-FACTOR; PHASE-II; TUMOR BURDEN; MODEL;
IMMUNONEUTRALIZATION; THERAPY; TRIAL
AB Background. Malignant ascites often has a profound impact on the quality of life of patients with refractory ovarian cancer. Current treatments, including dietary, medical, and procedural are often temporary and unsatisfactory options in patients approaching the end of life.
Case. We present a case of an 88 year-old receiving home hospice care with refractory ovarian cancer and severe symptomatic ascites. We performed a paracentesis and treated her with intraperitoneal bevacizumab with dramatic improvement in her ascites and the quality of her final weeks of life.
Conclusion. Intraperitoneal bevacizumab may be a useful 1001 in the palliation of malignant ascites and is worthy of further study. Published by Elsevier Inc.
C1 [Hamilton, Chad A.; Maxwell, G. Larry; Chemofsky, Mildred R.; Bernstein, Sarah A.; Farley, John H.; Rose, G. Scott] Walter Reed Army Med Ctr, Dept Obstet & Gynecol, Div Gynecol Oncol, Washington, DC 20307 USA.
RP Hamilton, CA (reprint author), Walter Reed Army Med Ctr, Dept Obstet & Gynecol, Div Gynecol Oncol, 6900 Georgia Ave NW, Washington, DC 20307 USA.
EM chad.hamilton@comcast.net
NR 15
TC 48
Z9 50
U1 0
U2 5
PU ACADEMIC PRESS INC ELSEVIER SCIENCE
PI SAN DIEGO
PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA
SN 0090-8258
J9 GYNECOL ONCOL
JI Gynecol. Oncol.
PD DEC
PY 2008
VL 111
IS 3
BP 530
EP 532
DI 10.1016/j.ygyno.2008.04.028
PG 3
WC Oncology; Obstetrics & Gynecology
SC Oncology; Obstetrics & Gynecology
GA 384PZ
UT WOS:000261758000026
PM 18561992
ER
PT J
AU Jones, JE
Muza, SR
Fulco, CS
Beidleman, BA
Tapia, ML
Cymerman, A
AF Jones, Juli E.
Muza, Stephen R.
Fulco, Charles S.
Beidleman, Beth A.
Tapia, Michael L.
Cymerman, Allen
TI Intermittent Hypoxic Exposure Does Not Improve Sleep at 4300 m
SO HIGH ALTITUDE MEDICINE & BIOLOGY
LA English
DT Article
DE sleep; altitude; altitude acclimatization; arterial oxygen saturation;
desaturation
ID ACUTE MOUNTAIN-SICKNESS; HIGH-ALTITUDE; WAKE IDENTIFICATION;
ACCLIMATIZATION; PERFORMANCE; ACTIGRAPHY
AB Jones, Juli E., Stephen R. Muza, Charles S. Fulco, Beth A. Beidleman, Michael L. Tapia, and Allen Cyerman. Intermittent hypoxic exposure does not improve sleep at 4300 m. High Alt. Med. Biol. 9: 281-288, 2008.-The purpose of this study was to determine in sea-level residents if 6 to 7 consecutive days of normobaric intermittent hypoxic exposure (IHE) (hypoxia room: 2-h ambient PO(2) = 90 mmHg sedentary and 1-h ambient PO(2) = 110 mmHg exercising at 80 +/- 5% of maximum heart rate) improved sleep quality (awakenings per hour) and quantity at altitude (4300 m). We hypothesized that IHE would improve sleep arterial oxygen saturation (SaO(2)) levels and decrease desaturation events, thereby contributing to improvements in sleep quality and quantity during subsequent exposure to high altitude. Ten sea-level residents (mean +/- SE: 22 +/- 1 yr, 179 +/- 2 cm, 79 +/- 3 kg) were assigned to an IHE group and six to a SHAM group (20 +/- 0.5 yr, 180 +/- 3 cm, 77 +/- 4 kg). Sleep quantity, SaO2, and heart rate ( HR) were monitored at sea level and during high altitude (i.e., 4300 m in a hypobaric chamber) before pretest ( PRE-T) and 60 h after posttest (POST-T) for the last IHE or SHAM treatment. Over the 6 to 7 days of IHE, resting SaO(2) increased from 75 +/- 1% to 81 +/- 3% in the IHE group, while the SHAM group remained at 98 +/- 1%. From PRE- T to POST-T at 4300-m exposure, both the IHE and SHAM groups had significantly higher sleep SaO(2), fewer desaturation events per hour, and an increase in the percentage of time asleep while sleeping (sleep percent). The IHE group, but not the SHAM group, had significantly lower sleep HR and a trend to more awakenings during the POST-T 4300-m exposure. These results indicate that although IHE treatment induced significant ventilatory acclimatization, relative to the SHAM group, IHE did not further improve sleep SaO(2) quality and quantity following rapid ascent to 4300 m. Rather, it is likely that the acquired ventilatory acclimatization was lost in the 60 h between the last IHE session and the POST-T altitude exposure.
C1 [Jones, Juli E.; Muza, Stephen R.; Fulco, Charles S.; Beidleman, Beth A.; Tapia, Michael L.; Cymerman, Allen] USA, Environm Med Res Inst, Thermal & Mt Med Div, Natick, MA 01760 USA.
RP Muza, SR (reprint author), USA, Environm Med Res Inst, Thermal & Mt Med Div, Kansas St, Natick, MA 01760 USA.
EM stephen.muza@us.army.mil
FU Army Medical Research and Materiel Command [ATO IV.MD.2006.01]
FX Funding was provided by U. S. Army Medical Research and Materiel Command
ATO IV.MD.2006.01.
NR 28
TC 6
Z9 6
U1 0
U2 1
PU MARY ANN LIEBERT INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1527-0297
J9 HIGH ALT MED BIOL
JI High Alt. Med. Biol.
PD DEC
PY 2008
VL 9
IS 4
BP 281
EP 287
DI 10.1089/ham.2008.1039
PG 7
WC Biophysics; Public, Environmental & Occupational Health; Sport Sciences
SC Biophysics; Public, Environmental & Occupational Health; Sport Sciences
GA 389IG
UT WOS:000262085500004
PM 19115911
ER
PT J
AU Salas, E
DiazGranados, D
Klein, C
Burke, CS
Stagl, KC
Goodwin, GF
Halpin, SM
AF Salas, Eduardo
DiazGranados, Deborah
Klein, Cameron
Burke, C. Shawn
Stagl, Kevin C.
Goodwin, Gerald F.
Halpin, Stanley M.
TI Does Team Training Improve Team Performance? A Meta-Analysis
SO HUMAN FACTORS
LA English
DT Review
ID CORRELATION-COEFFICIENTS; DECISION-MAKING; WORK; IMPACT; PROGRAM; MODEL;
INTERDEPENDENCE; ORGANIZATIONS; INTEGRATION; LEADERSHIP
AB Objective: This research effort leveraged the science of training to guide a taxonomic integration and a series of meta-analyses to gauge the effectiveness and boundary conditions of team training interventions for enhancing team outcomes. Background: Disparate effect sizes across primary studies have made it difficult to determine the true strength of the relationships between team training techniques and team Outcomes. Method: Several meta-analytic integrations were conducted to examine the relationships between team training interventions and team functioning. Specifically, we assessed the relative effectiveness of these interventions on team cognitive, affective, process,and performance outcomes. Training content, team membership stability, and team size were investigated as potential moderators of the relationship between team training and outcomes. In total, the database consisted of 93 effect sizes representing 2,650 teams. Results: The results Suggested that moderate, positive relationships exist between team training interventions and each of the outcome types. The findings of moderator analyses indicated that training content, team membership stability, and team size moderate the effectiveness of these interventions. Conclusion: Our findings suggest that team training interventions are a viable approach organizations can take in order to enhance team outcomes. They are useful for improving cognitive Outcomes, affective outcomes, teamwork processes, and performance outcomes. Moreover, results suggest that training content, team membership stability, and team size moderate the effectiveness of team training interventions. Application: Applications of the results from this research are numerous. Those who design and administer training can benefit from these findings in order to improve the effectiveness of their team training interventions.
C1 [Salas, Eduardo; DiazGranados, Deborah; Burke, C. Shawn] Univ Cent Florida, Inst Simulat & Training, Orlando, FL 32826 USA.
[Salas, Eduardo; DiazGranados, Deborah; Klein, Cameron] Univ Cent Florida, Dept Psychol, Orlando, FL 32826 USA.
[Stagl, Kevin C.] Talent Threshold LLC, Orlando, FL USA.
[Goodwin, Gerald F.] Army Res Inst, Basic Res Unit, Arlington, VA USA.
[Halpin, Stanley M.] Army Res Inst, Leader Dev Unit, Ft Leavenworth Res Unit, Ft Leavenworth, KS USA.
RP Salas, E (reprint author), Univ Cent Florida, Inst Simulat & Training, 3100 Technol Pkwy, Orlando, FL 32826 USA.
EM esalas@ist.ucf.edu
FU U.S. Army Research Institute for the Behavioral and Social Sciences
[W74V8H-04-C0025]
FX This work was supported by funding from the U.S. Army Research Institute
for the Behavioral and Social Sciences (Contract W74V8H-04-C0025). The
views, opinions, and/or findings contained in this paper are those of
the authors and should not be construed as an official position, policy,
or decision of the Department of the Army or the University of Central
Florida.; We would like to thank Huy Le, John Mathieu, and Florian
Jentsch for their insightful guidance during the course of this project.
We would also like to acknowledge Shannon Scielzo and Samuel Wooten for
their assistance during the early coding portions of the project.
NR 157
TC 155
Z9 157
U1 14
U2 90
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 0018-7208
EI 1547-8181
J9 HUM FACTORS
JI Hum. Factors
PD DEC
PY 2008
VL 50
IS 6
BP 903
EP 933
DI 10.1518/001872008X375009
PG 31
WC Behavioral Sciences; Engineering, Industrial; Ergonomics; Psychology,
Applied; Psychology
SC Behavioral Sciences; Engineering; Psychology
GA 410LB
UT WOS:000263577400005
PM 19292013
ER
PT J
AU Veliadis, V
Snook, M
McNutt, T
Hearne, H
Potyraj, P
Lelis, A
Scozzie, C
AF Veliadis, V.
Snook, M.
McNutt, T.
Hearne, H.
Potyraj, P.
Lelis, Aivars
Scozzie, C.
TI A 2055-V (at 0.7 mA/cm(2)) 24-A (at 706 W/cm(2)) Normally On 4H-SiC JFET
With 6.8-mm(2) Active Area and Blocking-Voltage Capability Reaching the
Material Limit
SO IEEE ELECTRON DEVICE LETTERS
LA English
DT Article
DE Edge termination; guard rings; high current; high power; high voltage;
junction field-effect transistor (JFET); large area; normally on;
vertical channel; 4H-SiC
ID TEMPERATURE
AB A normally on 4H-SiC vertical-junction field-effect transistor (VJFET) of 6.8-mm(2) active area was manufactured in seven photolithographic levels with no epitaxial regrowth and a single masked ion-implantation event. The VJFET exhibits low leakage currents with very sharp onsets of voltage breakdowns. At a forward gate bias of 2.5 V, the VJFET outputs 24 A (353 A/cm(2)) at a forward drain-voltage drop of 2 V (706 W/cm(2)), with a current gain of I-D/I-G = 21818, and a specific ON-state resistance of 5.7 m Omega center dot cm(2). Self-aligned floating guard rings provide edge termination that blocks 2055 V at a gate bias of -37 V and a drain-current density of 0.7 mA/cm(2). This blocking voltage corresponds to 94.4% of the VJFET's 11.7-mu m/3.46 x 10(15)-cm(3) SiC drift layer limit and is the highest reported blocking-voltage efficiency of any SiC power device under similar drain-current-density conditions.
C1 [Veliadis, V.; Snook, M.; McNutt, T.; Hearne, H.; Potyraj, P.] Northrop Grumman Adv Technol Lab, Linthicum, MD 21090 USA.
[Lelis, Aivars; Scozzie, C.] USA, Res Lab, Adelphi, MD 20783 USA.
RP Veliadis, V (reprint author), Northrop Grumman Adv Technol Lab, Linthicum, MD 21090 USA.
FU U.S. Army Research Laboratory [W91INF-06-2-0002]
FX This work was supported by the U.S. Army Research Laboratory under
Cooperative Agreement W91INF-06-2-0002. The review of this letter was
arranged by Editor S.-H. Ryu.
NR 12
TC 26
Z9 30
U1 0
U2 5
PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
PI PISCATAWAY
PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA
SN 0741-3106
EI 1558-0563
J9 IEEE ELECTR DEVICE L
JI IEEE Electron Device Lett.
PD DEC
PY 2008
VL 29
IS 12
BP 1325
EP 1327
DI 10.1109/LED.2008.2006766
PG 3
WC Engineering, Electrical & Electronic
SC Engineering
GA 389AL
UT WOS:000262062000012
ER
PT J
AU Masrur, MA
AF Masrur, M. Abul
TI Penalty for Fuel Economy-System Level Perspectives on the Reliability of
Hybrid Electric Vehicles During Normal and Graceful Degradation
Operation
SO IEEE SYSTEMS JOURNAL
LA English
DT Article
DE Controller area network (CAN) controller; graceful degradation; hybrid
electric vehicle (HEV); inverter; motor; multiplex system; power
electronics; reliability
AB Generally people tend to think only in terms of fuel economy and additional cost premium on vehicle price while discussing about hybrid electric vehicles (HEV). This paper tries to emphasize that the overall acceptability of a vehicle also has to do with its system level reliability. It discusses the issue of system level reliability in hybrid electric vehicles from a quantitative point of view. It also introduces a quantitative meaning to the concept of graceful degradation and mode of operation under graceful degradation condition. All these are discussed in stages, starting from a regular internal combustion engine based vehicle, and later transition of those to hybrid electric vehicles. This paper intends to drive the point that in HEV, one of the penalties for fuel economy that has to be paid comes in terms of reliability.
C1 USA, RDECOM TARDEC, Warren, MI 48397 USA.
RP Masrur, MA (reprint author), USA, RDECOM TARDEC, Warren, MI 48397 USA.
EM md.abul.masrur@us.army.mil
NR 7
TC 8
Z9 8
U1 0
U2 5
PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
PI PISCATAWAY
PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA
SN 1932-8184
J9 IEEE SYST J
JI IEEE Syst. J.
PD DEC
PY 2008
VL 2
IS 4
BP 476
EP 483
DI 10.1109/JSYST.2008.2005714
PG 8
WC Computer Science, Information Systems; Engineering, Electrical &
Electronic; Operations Research & Management Science; Telecommunications
SC Computer Science; Engineering; Operations Research & Management Science;
Telecommunications
GA V10NF
UT WOS:000207470000004
ER
PT J
AU Ho, J
Jow, TR
Boggs, SA
AF Ho, Janet
Jow, T. Richard
Boggs, Steven A.
TI Implications of Advanced Capacitor Dielectrics for Performance of
Metallized Film Capacitor Windings
SO IEEE TRANSACTIONS ON DIELECTRICS AND ELECTRICAL INSULATION
LA English
DT Article; Proceedings Paper
CT Volta Colloquium on Partial Discharge Measuements
CY 2007
CL Como, ITALY
DE Metallized film capacitors; pulsed discharge; ESL; ESR; dielectric
constant; capacitor design
ID ENERGY-STORAGE CAPACITORS
AB A range of high dielectric capacitor films is under development with the objective of improving the energy density of pulsed discharge capacitors. A substantial change in capacitor film dielectric constant has implications for capacitor design and function. This paper develops formulas for equivalent series resistance (ESR) and equivalent series inductance (ESL) of a cylindrical capacitor winding as a function of material properties and winding design. A numerical approach is used to investigate the frequency-dependent ESR and ESL, after which formulas are developed for winding inductance based on a resistive current distribution in the winding. Analyses are carried out for a cylindrical metallized film winding in which the return conductor is brought either through the center of the core on which the film is wound or coaxially up the outside of the winding, so that both connections are made from the same end of the capacitor with minimal inductance. The implications of moving to high dielectric constant film are investigated on the basis of this analysis.
C1 [Ho, Janet; Jow, T. Richard] USA, Res Lab, Adelphi, MD 20783 USA.
[Boggs, Steven A.] Univ Connecticut, Inst Mat Sci, Storrs, CT 06268 USA.
[Boggs, Steven A.] Univ Connecticut, Dept Elect Engn, Storrs, CT 06268 USA.
[Boggs, Steven A.] Univ Connecticut, Dept Phys, Storrs, CT 06268 USA.
RP Ho, J (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
NR 4
TC 9
Z9 9
U1 1
U2 5
PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
PI PISCATAWAY
PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA
SN 1070-9878
J9 IEEE T DIELECT EL IN
JI IEEE Trns. Dielectr. Electr. Insul.
PD DEC
PY 2008
VL 15
IS 6
BP 1754
EP 1760
PG 7
WC Engineering, Electrical & Electronic; Physics, Applied
SC Engineering; Physics
GA 378GI
UT WOS:000261308800034
ER
PT J
AU Toonen, RC
Haselby, CC
Blick, RH
AF Toonen, Ryan Christopher
Haselby, Cyrus C.
Blick, Robert H.
TI An Ultrawideband Cross-Correlation Radiometer for Mesoscopic Experiments
SO IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
LA English
DT Article
DE Correlation; correlators; microwave radiometry; noise; noise
measurement; quantum-effect semiconductor devices; radiometry;
temperature measurement
ID HANBURY-BROWN
AB We have designed, built, and tested a cross-correlation radiometer for detecting quantum statistical fluctuations in mesoscopic experiments. We present the details of our design and the results of our characterization. Our instrument operates over the X- and Ku-bands (8-18 GHz). Digital signal processing techniques are used to provide robustness against instrumentation drifts and offsets. The economized version of our instrument can detect, with sufficient correlation efficiency, noise signals having power levels as low as 10 fW. The modularity of our design allows one to easily alter the specifications (such as the bandwidth and the sensitivity) by simply replacing individual components. Index Terms-Correlation, correlators, microwave radiometry, noise, noise measurement, quantum-effect semiconductor devices, radiometry, temperature measurement.
C1 [Toonen, Ryan Christopher] Natl Inst Stand & Technol, Boulder, CO 80305 USA.
[Haselby, Cyrus C.] Univ Calif Los Angeles, Dept Elect Engn, Los Angeles, CA 90095 USA.
[Blick, Robert H.] Univ Wisconsin, Madison, WI 53706 USA.
RP Toonen, RC (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
NR 22
TC 1
Z9 1
U1 0
U2 3
PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
PI PISCATAWAY
PA 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA
SN 0018-9456
EI 1557-9662
J9 IEEE T INSTRUM MEAS
JI IEEE Trans. Instrum. Meas.
PD DEC
PY 2008
VL 57
IS 12
BP 2874
EP 2879
DI 10.1109/TIM.2008.925011
PG 6
WC Engineering, Electrical & Electronic; Instruments & Instrumentation
SC Engineering; Instruments & Instrumentation
GA 373YF
UT WOS:000261008700023
ER
PT J
AU Darwish, AM
Bayba, AJ
Hung, HA
AF Darwish, Ali M.
Bayba, Andrew J.
Hung, H. Alfred
TI Utilizing Diode Characteristics for GaN HEMT Channel Temperature
Prediction
SO IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES
LA English
DT Article
DE Channel temperature; field-effect transistor (FET); GaN; high-electron
mobility transistor (HEMT); reliability; thermal resistance
ID FIELD-EFFECT TRANSISTORS; THERMAL-RESISTANCE; RAMAN-SPECTROSCOPY;
PERFORMANCE; DEVICES
AB Measuring channel temperature in GaN high-electron mobility transistors (HEMTs) is challenging due to the submicrometer dimensions of the gate fingers. The HEMT characteristics are electrically and thermally dependent. The channel temperature is measured using the Schottky gate-diode forward characteristics and compared with results of simulation, theory, and experimental evidence. The pulsed gate-diode forward resistance and threshold voltage predict channel temperatures that agree well with other methods. The technique presented provides a fast, easily implementable methodology for estimating channel temperature.
C1 [Darwish, Ali M.; Bayba, Andrew J.; Hung, H. Alfred] USA, Res Lab, Adelphi, MD 20783 USA.
RP Darwish, AM (reprint author), USA, Res Lab, Adelphi, MD 20783 USA.
NR 20
TC 13
Z9 14
U1 0
U2 11
PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
PI PISCATAWAY
PA 445 HOES LANE, PISCATAWAY, NJ 08855 USA
SN 0018-9480
J9 IEEE T MICROW THEORY
JI IEEE Trans. Microw. Theory Tech.
PD DEC
PY 2008
VL 56
IS 12
BP 3188
EP 3192
DI 10.1109/TMTT.2008.2007364
PG 5
WC Engineering, Electrical & Electronic
SC Engineering
GA 386PS
UT WOS:000261895700022
ER
PT J
AU Matveev, IB
Serbin, SI
Lux, SM
AF Matveev, Igor B.
Serbin, Serhiy I.
Lux, Scott M.
TI Efficiency of a Hybrid-Type Plasma-Assisted Fuel Reformation System
SO IEEE TRANSACTIONS ON PLASMA SCIENCE
LA English
DT Article
DE Coal; combustion; liquid fuel; plasma; reformation; waste processing
AB The major advantages of a new plasma-assisted fuel reformation system are its cost effectiveness and technical efficiency. Applied Plasma Technologies has proposed its new highly efficient hybrid-type plasma-assisted system for organic fuel combustion and gasification. The system operates as a multimode multipurpose reactor in a wide range of plasma feedstock gases and turndown ratios. This system also has convenient and simultaneous feeding of several reagents in the reaction zone such as liquid fuels, coal, steam, and air. A special methodology has been developed for such a system in terms of heat balance evaluation and optimization. This methodology considers all existing and possible energy streams, which could influence the system's efficiency . The developed hybrid-type plasma system could be suitable for combustion applications, mobile and autonomous small- to mid-size liquid fuel and coal gasification modules, hydrogen-rich gas generators, waste-processing facilities, and plasma chemical reactors.
C1 [Matveev, Igor B.] Appl Plasma Technol, Mclean, VA 22101 USA.
[Serbin, Serhiy I.] Natl Univ Shipbldg, Turbine Units Dept, UA-54025 Mykolayiv, Ukraine.
[Lux, Scott M.] USA, Ctr Res Dev & Engn, Construct Engn Res Lab, Champaign, IL 61826 USA.
RP Matveev, IB (reprint author), Appl Plasma Technol, Mclean, VA 22101 USA.
EM i.matveev@att.net; serhiy@serbin.mk.ua; Scott.M.Lux@usace.army.mil
RI Serbin, Serhiy/E-9056-2016;
OI Serbin, Serhiy/0000-0002-3423-2681
NR 17
TC 12
Z9 13
U1 0
U2 7
PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
PI PISCATAWAY
PA 445 HOES LANE, PISCATAWAY, NJ 08855 USA
SN 0093-3813
J9 IEEE T PLASMA SCI
JI IEEE Trans. Plasma Sci.
PD DEC
PY 2008
VL 36
IS 6
BP 2940
EP 2946
DI 10.1109/TPS.2008.2006843
PG 7
WC Physics, Fluids & Plasmas
SC Physics
GA 389AK
UT WOS:000262061900010
ER
PT J
AU Torrieri, D
Valenti, MC
AF Torrieri, Don
Valenti, Matthew C.
TI Constellation Labeling Maps for Low Error Floors
SO IEEE TRANSACTIONS ON WIRELESS COMMUNICATIONS
LA English
DT Article; Proceedings Paper
CT IEEE Military Communications Conference (MILCOM 2007)
CY OCT 29-31, 2007
CL Orlando, FL
SP IEEE
DE Constellation; labeling map; error floor; iterative decoding;
bit-interleaved coded modulation
ID INTERLEAVED CODED MODULATION; DESIGN; BICM
AB A constellation labeling map is the assignment of a bit pattern to each symbol in a signal-set constellation. In a system with iterative decoding and demodulation, the error floor of the bit error rate is highly dependent on the labeling map. A simple class of labeling maps that significantly lower the error floors is presented. Examples show the applications of the proposed mapping to multiple phase-shift keying (MPSK), quadrature amplitude modulation (QAM), and continuous-phase frequency-shift keying (CPFSK). Simulation results indicate that the proposed labeling maps are comparable to or better than other labeling maps in providing a low error floor. A major advantage of the proposed labeling maps is that they are easily generated even when the alphabet size is large.
C1 [Torrieri, Don] USA, Res Lab, Adelphi, MD 20783 USA.
[Valenti, Matthew C.] W Virginia Univ, Morgantown, WV 26506 USA.
RP Torrieri, D (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM dtorr@arl.army.mil
OI Valenti, Matthew/0000-0001-6089-0509
NR 12
TC 4
Z9 4
U1 0
U2 3
PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
PI PISCATAWAY
PA 445 HOES LANE, PISCATAWAY, NJ 08855 USA
SN 1536-1276
J9 IEEE T WIREL COMMUN
JI IEEE Trans. Wirel. Commun.
PD DEC
PY 2008
VL 7
IS 12
BP 5401
EP 5407
DI 10.1109/T-WC.2008.071276
PG 7
WC Engineering, Electrical & Electronic; Telecommunications
SC Engineering; Telecommunications
GA 387AM
UT WOS:000261924100035
ER
PT J
AU Mi, C
Bai, H
Wang, C
Gargies, S
AF Mi, C.
Bai, H.
Wang, C.
Gargies, S.
TI Operation, design and control of dual H-bridge-based isolated
bidirectional DC DC converter
SO IET POWER ELECTRONICS
LA English
DT Article
AB The operation, design and control of an isolated bidirectional DC-DC converter for hybrid electric vehicle energy management applications are discussed. Different operation modes and boundary conditions are distinguished by phase-shift angle and load conditions. The absolute and relative output voltage ripple was derived. The dead-band effect and safe operational area are further investigated. The relations between output power and leakage inductance and switching frequency are also presented. The proposed converter was simulated and a prototype was built and tested. Experiments on the converter's steady state and transient operations validated the design and simulation.
C1 [Mi, C.; Bai, H.] Univ Michigan, Dept Elect & Comp Engn, Dearborn, MI 48128 USA.
[Wang, C.] NW Polytech Univ, Coll Marine Engn, Xian 710072, Shaanxi, Peoples R China.
[Gargies, S.] USA, RDECOM TARDEC, Warren, MI 48397 USA.
RP Mi, C (reprint author), Univ Michigan, Dept Elect & Comp Engn, 4901 Evergreen Rd, Dearborn, MI 48128 USA.
EM chrismi@umich.edu
NR 21
TC 56
Z9 66
U1 1
U2 8
PU INST ENGINEERING TECHNOLOGY-IET
PI HERTFORD
PA MICHAEL FARADAY HOUSE SIX HILLS WAY STEVENAGE, HERTFORD SG1 2AY, ENGLAND
SN 1755-4535
J9 IET POWER ELECTRON
JI IET Power Electron.
PD DEC
PY 2008
VL 1
IS 4
BP 507
EP 517
DI 10.1049/iet-pel:20080004
PG 11
WC Engineering, Electrical & Electronic
SC Engineering
GA V11BW
UT WOS:000207508100009
ER
PT J
AU Poly, F
Read, TD
Chen, YH
Monteiro, MA
Serichantalergs, O
Pootong, P
Bodhidatta, L
Mason, CJ
Rockabrand, D
Baqar, S
Porter, CK
Tribble, D
Darsley, M
Guerry, P
AF Poly, Frederic
Read, Timothy D.
Chen, Yu-Han
Monteiro, Mario A.
Serichantalergs, Oralak
Pootong, Piyarat
Bodhidatta, Ladaporn
Mason, Carl J.
Rockabrand, David
Baqar, Shahida
Porter, Chad K.
Tribble, David
Darsley, Michael
Guerry, Patricia
TI Characterization of Two Campylobacter jejuni Strains for Use in
Volunteer Experimental-Infection Studies
SO INFECTION AND IMMUNITY
LA English
DT Article
ID GUILLAIN-BARRE-SYNDROME; MILLER-FISHER-SYNDROME; GENOME SEQUENCE;
TETRACYCLINE RESISTANCE; PHASE VARIATION; LIPOOLIGOSACCHARIDE;
BIOSYNTHESIS; CARBOHYDRATE; LIPOPOLYSACCHARIDES; IDENTIFICATION
AB The development of vaccines against Campylobacter jejuni would be facilitated by the ability to perform phase II challenge studies. However, molecular mimicry of the lipooligosaccharide (LOS) of most C. jejuni strains with human gangliosides presents safety concerns about the development of Guillain-Barre syndrome. Clinical isolates of C. jejuni that appeared to lack genes for the synthesis of ganglioside mimics were identified by DNA probe analyses. Two clinical isolates from Southeast Asia (strains BH-01-0142 and CG8421) were determined to express the LOS type containing N-acetyl quinovosamine. No ganglioside structures were observed to be present in the LOSs of these strains, and pyrosequence analyses of the genomes of both strains confirmed the absence of genes involved in ganglioside mimicry. The capsule polysaccharide (CPS) of BH-01-0142 was determined to be composed of galactose (Gal), 6-deoxy-ido-heptose, and, in smaller amounts, D-glycero-D-ido-heptose, and the CPS of CG8421 was observed to contain Gal, 6-deoxy-altro-heptose, N-acetyl-glucosamine, and minor amounts of 6-deoxy-3-O-Me-altro-heptose. Both CPSs were shown to carry O-methyl-phosphoramidate. The two genomes contained strain-specific zones, some of which could be traced to a plasmid origin, and both contained a large chromosomal insertion related to the CJEI3 element of C. jejuni RM1221. The genomes of both strains shared a high degree of similarity to each other and, with the exception of the capsule locus of CG8421, to the type strain of the HS3 serotype, TGH9011.
C1 [Guerry, Patricia] Naval Med Res Ctr, Enter Dis Dept, Silver Spring, MD 20910 USA.
[Chen, Yu-Han; Monteiro, Mario A.] Univ Guelph, Guelph, ON N1G 2W1, Canada.
[Serichantalergs, Oralak; Pootong, Piyarat; Bodhidatta, Ladaporn; Mason, Carl J.] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand.
[Tribble, David] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
[Darsley, Michael] ACE Biosci, Odense, Denmark.
RP Guerry, P (reprint author), Naval Med Res Ctr, Enter Dis Dept, 503 Robert Grant Ave, Silver Spring, MD 20910 USA.
EM patricia.guerry@med.navy.mil
RI Porter, Chad/A-8026-2011; Read, Timothy/E-6240-2011; Guerry,
Patricia/A-8024-2011;
OI MASON, CARL/0000-0002-3676-2811
FU Military Infectious Diseases Research Program Work Unit
[6000.RAD1.DA3.A308]; NSERC; ACE Biosciences
FX We thank Nicci Nolan, Shannon Lentz, Cheryl Ewing, Gary Majam, Julie
Phan, and Lisa Applebee at the NMRC for their contributions to this
study; Helen Tabor of the Canadian Microbiology Reference Laboratory in
Winnipeg for Penner serotyping; and Michael Prouty for his comments on
the manuscript.; Work at the NMRC was funded by the Military Infectious
Diseases Research Program Work Unit 6000.RAD1.DA3.A308. M. A. M. was
funded by the NSERC and ACE Biosciences.; The views expressed in this
work are those of the authors and do not necessarily reflect the
official policy or position of the Navy, the Department of Defense, or
the U. S. government.
NR 64
TC 28
Z9 28
U1 0
U2 2
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0019-9567
J9 INFECT IMMUN
JI Infect. Immun.
PD DEC
PY 2008
VL 76
IS 12
BP 5655
EP 5667
DI 10.1128/IAI.00780-08
PG 13
WC Immunology; Infectious Diseases
SC Immunology; Infectious Diseases
GA 373WJ
UT WOS:000261003900023
PM 18809665
ER
PT J
AU Caserta, JA
Hale, ML
Popoff, MR
Stiles, BG
McClane, BA
AF Caserta, Justin A.
Hale, Martha L.
Popoff, Michel R.
Stiles, Bradley G.
McClane, Bruce A.
TI Evidence that Membrane Rafts Are Not Required for the Action of
Clostridium perfringens Enterotoxin
SO INFECTION AND IMMUNITY
LA English
DT Article
ID TIGHT-JUNCTION PROTEINS; CACO-2 CELLS; LIPID RAFTS; PORE FORMATION;
ANTHRAX TOXIN; IOTA-TOXIN; CHOLESTEROL; MICRODOMAINS; OCCLUDIN; BINDING
AB The action of bacterial pore-forming toxins typically involves membrane rafts for binding, oligomerization, and/or cytotoxicity. Clostridium perfringens enterotoxin (CPE) is a pore-forming toxin with a unique, multistep mechanism of action that involves the formation of complexes containing tight junction proteins that include claudins and, sometimes, occludin. Using sucrose density gradient centrifugation, this study evaluated whether the CPE complexes reside in membrane rafts and what role raft microdomains play in complex formation and CPE-induced cytotoxicity. Western blot analysis revealed that the small CPE complex and the CPE hexamer 1 (CH-1) complex, which is sufficient for CPE-induced cytotoxicity, both localize outside of rafts. The CH-2 complex was also found mainly in nonraft fractions, although a small pool of raft-associated CH-2 complex that was sensitive to cholesterol depletion with methyl-beta-cyclodextrin (M beta CD) was detected. Pretreatment of Caco-2 cells with M beta CD had no appreciable effect on CPE-induced cytotoxicity. Claudin-4 was localized to Triton X-100-soluble gradient fractions of control or CPE-treated Caco-2 cells, indicating a raft-independent association for this CPE receptor. In contrast, occludin was present in raft fractions of control Caco-2 cells. Treatment with either M beta CD or CPE caused most occludin molecules to shift out of lipid rafts, possibly due (at least in part) to the association of occludin with the CH-2 complex. Collectively, these results suggest that CPE is a unique pore-forming toxin for which membrane rafts are not required for binding, oligomerization/pore formation, or cytotoxicity.
C1 [McClane, Bruce A.] Univ Pittsburgh, Sch Med, Dept Microbiol & Mol Genet, Pittsburgh, PA 15261 USA.
[Caserta, Justin A.; McClane, Bruce A.] Univ Pittsburgh, Sch Med, Mol Virol & Microbiol Grad Program, Pittsburgh, PA 15261 USA.
[Hale, Martha L.; Stiles, Bradley G.] USA, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA.
[Popoff, Michel R.] Inst Pasteur, Unite Bacteries Anaerobies & Toxines, Paris, France.
RP McClane, BA (reprint author), Univ Pittsburgh, Sch Med, Dept Microbiol & Mol Genet, E1240 BSTWR, Pittsburgh, PA 15261 USA.
EM bamcc@pitt.edu
FU National Institute of Allergy and Infectious Diseases [R37-AI019844-24,
AI060525]
FX This work was supported by Public Health Service grant R37-AI019844-24
and T32 predoctoral training grant AI060525 from the National Institute
of Allergy and Infectious Diseases.
NR 37
TC 13
Z9 13
U1 0
U2 0
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0019-9567
J9 INFECT IMMUN
JI Infect. Immun.
PD DEC
PY 2008
VL 76
IS 12
BP 5677
EP 5685
DI 10.1128/IAI.00854-08
PG 9
WC Immunology; Infectious Diseases
SC Immunology; Infectious Diseases
GA 373WJ
UT WOS:000261003900025
PM 18809663
ER
PT J
AU Noland, GS
Hendel-Paterson, B
Min, XM
Moormann, AM
Vulule, JM
Narum, DL
Lanar, DE
Kazura, JW
John, CC
AF Noland, Gregory S.
Hendel-Paterson, Brett
Min, Xinan M.
Moormann, Ann M.
Vulule, John M.
Narum, David L.
Lanar, David E.
Kazura, James W.
John, Chandy C.
TI Low Prevalence of Antibodies to Preerythrocytic but Not Blood-Stage
Plasmodium falciparum Antigens in an Area of Unstable Malaria
Transmission Compared to Prevalence in an Area of Stable Malaria
Transmission
SO INFECTION AND IMMUNITY
LA English
DT Article
ID MEROZOITE SURFACE-ANTIGEN; CLINICAL MALARIA; CIRCUMSPOROZOITE PROTEIN;
WESTERN KENYA; HIGHLAND AREA; ADHESIVE PROTEIN; ENDEMIC AREA; RESPONSES;
PROTECTION; CHILDREN
AB In areas where levels of transmission of Plasmodium falciparum are high and stable, the age-related acquisition of high-level immunoglobulin G (IgG) antibodies to preerythrocytic circumsporozoite protein (CSP) and liver-stage antigen 1 (LSA-1) has been associated with protection from clinical malaria. In contrast, age-related protection from malaria develops slowly or not at all in residents of epidemic-prone areas with unstable low levels of malaria transmission. We hypothesized that this suboptimal clinical and parasitological immunity may in part be due to reduced antibodies to CSP or LSA-1 and/or vaccine candidate blood-stage antigens. Frequencies and levels of IgG antibodies to CSP, LSA-1, thrombospondin-related adhesive protein ( TRAP), apical membrane antigen 1 (AMA-1), erythrocyte binding antigen 175 (EBA-175), and merozoite surface protein 1 (MSP-1) were compared in 243 Kenyans living in a highland area of unstable transmission and 210 residents of a nearby lowland area of stable transmission. Levels of antibodies to CSP, LSA-1, TRAP, and AMA-1 in the oldest age group (>40 years) in the unstable transmission area were lower than or similar to those of children 2 to 6 years old in the stable transmission area. Only 3.3% of individuals in the unstable transmission area had high levels of IgG (>2 arbitrary units) to both CSP and LSA-1, compared to 43.3% of individuals in the stable transmission area. In contrast, antibody levels to and frequencies of MSP-1 and EBA-175 were similar in adults in areas of stable and unstable malaria transmission. Suboptimal immunity to malaria in areas of unstable malaria transmission may relate in part to infrequent high-level antibodies to preerythrocytic antigens and AMA-1.
C1 [John, Chandy C.] Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA.
[Moormann, Ann M.; Kazura, James W.] Case Western Reserve Univ, Cleveland, OH 44106 USA.
[Vulule, John M.] Kenya Govt Med Res Ctr, Kisumu, Kenya.
[Narum, David L.] NIH, Bethesda, MD 20892 USA.
[Lanar, David E.] Walter Reed Army Inst Res, Silver Spring, MD USA.
RP John, CC (reprint author), Univ Minnesota, Dept Pediat, 717 Delaware St,SE Room 363,MC1932, Minneapolis, MN 55455 USA.
EM ccj@umn.edu
RI John, Chandy/B-4164-2008; Lanar, David/B-3560-2011
FU National Institutes of Allergy and Infectious Diseases [AI01572,
AI056270, AI43906]
FX This study was supported by grants from the National Institutes of
Allergy and Infectious Diseases, AI01572 and AI056270 (C. C. J.) and
AI43906 (J. W. K.).; We thank the study participants for their
involvement in this study. We thank David Koech, Jackson Abuya, and
Livingstone Wanyama for their work in the field collection of these
samples and microscopy testing. The sample collection, field work, and
initial testing for this study were performed while C. C. J. was at Case
Western Reserve University.; This work is published with the permission
of the Office of the Director of the Kenya Medical Research Institute.
NR 33
TC 22
Z9 22
U1 1
U2 1
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0019-9567
J9 INFECT IMMUN
JI Infect. Immun.
PD DEC
PY 2008
VL 76
IS 12
BP 5721
EP 5728
DI 10.1128/IAI.00591-08
PG 8
WC Immunology; Infectious Diseases
SC Immunology; Infectious Diseases
GA 373WJ
UT WOS:000261003900030
PM 18809666
ER
PT J
AU Rossi, CA
Ulrich, M
Norris, S
Reed, DS
Pitt, LM
Leffel, EK
AF Rossi, Cynthia A.
Ulrich, Melanie
Norris, Sarah
Reed, Douglas S.
Pitt, Louise M.
Leffel, Elizabeth K.
TI Identification of a Surrogate Marker for Infection in the African Green
Monkey Model of Inhalation Anthrax
SO INFECTION AND IMMUNITY
LA English
DT Article
ID EQUINE ENCEPHALITIS-VIRUS; EXPERIMENTAL RESPIRATORY ANTHRAX;
BACILLUS-ANTHRACIS; CYNOMOLGUS MACAQUES; CERCOPITHECUS-AETHIOPS;
PROTECTIVE ANTIGEN; AEROSOL EXPOSURE; MACACA MULATTA; RHESUS-MONKEYS;
ENTEROTOXIN-B
AB In 2001, a bioterrorism attack involving Bacillus anthracis spore-laced letters resulted in 22 cases of inhalation anthrax, with five fatalities. This incident identified gaps in our health care system and precipitated a renewed interest in identifying both therapeutics and rapid diagnostic assays. To address those gaps, well-characterized animal models that resemble the human disease are needed. In addition, a rapid assay for a reliable diagnostic marker is key to the success of these efforts. In this study, we exposed African green monkeys to B. anthracis spores; examined clinical signs and physiological parameters, including fever, heart rate, complete blood count, and bacteremia; and evaluated the PCR assay and electrochemiluminescence (ECL) immunoassay for the biomarkers protective antigen and capsule. The results demonstrated that although there were neither objective clinical nor physiological signs that consistently identified either infection or the onset of clinical anthrax disease, the African green monkey is a suitable animal model exhibiting a disease course similar to that observed in the rhesus model and humans. We also demonstrated that detection of the biomarkers protective antigen and capsule correlated with bacterial loads in the blood of these nonhuman primates. The ECL immunoassay described here is simple and sensitive enough to provide results in one to two hours, making this assay a viable option for use in the diagnosis of anthrax, leading to timely initiation of treatment, which is a key component of B. anthracis therapeutic development.
C1 [Rossi, Cynthia A.; Ulrich, Melanie] USA, Med Res Inst Infect Dis, Diagnost Syst Div, Ft Detrick, MD 21702 USA.
[Norris, Sarah] USA, Med Res Inst Infect Dis, Res Support Div, Ft Detrick, MD 21702 USA.
[Reed, Douglas S.; Pitt, Louise M.; Leffel, Elizabeth K.] USA, Med Res Inst Infect Dis, Ctr Aerobiol Sci, Ft Detrick, MD 21702 USA.
RP Leffel, EK (reprint author), Natl Biodef Anal & Countermeasures Ctr, Battelle Natl Biodef Inst, 110 Thomas Johnson Dr,Suite 200, Frederick, MD 21702 USA.
EM leffele@nbacc.net
OI Reed, Douglas/0000-0003-0076-9023
FU National Institute of Allergy and Infectious Diseases, Bethesda,; Joint
Science and Technology Office for Chemical and Biological Defense
Program, Defense Threat Reduction Agency.
FX This research was sponsored by the National Institute of Allergy and
Infectious Diseases, Bethesda, MD. Assay development was funded by the
Joint Science and Technology Office for Chemical and Biological Defense
Program, Defense Threat Reduction Agency.; The views, opinions, and/or
findings contained herein are those of the authors and should not be
construed as an official Department of Army position, policy, or
decision unless so designated by other documentation. The authors do not
have a commercial or other association that would pose a conflict of
interest.; We are grateful to D. Norwood, P. Hobart, and K. Kenyon for
critically reviewing the manuscript, and we thank D. Dyer, S. Coyne, and
B. Kearney for their excellent technical assistance.
NR 55
TC 23
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U1 0
U2 4
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0019-9567
J9 INFECT IMMUN
JI Infect. Immun.
PD DEC
PY 2008
VL 76
IS 12
BP 5790
EP 5801
DI 10.1128/IAI.00520-08
PG 12
WC Immunology; Infectious Diseases
SC Immunology; Infectious Diseases
GA 373WJ
UT WOS:000261003900038
PM 18852240
ER
PT J
AU Lerdthusnee, K
Nigro, J
Monkanna, T
Leepitakrat, W
Leepitakrat, S
Insuan, S
Charoensongsermkit, W
Khlaimanee, N
Akkagraisee, W
Chayapum, K
Jones, JW
AF Lerdthusnee, Kriangkrai
Nigro, Joseph
Monkanna, Taweesak
Leepitakrat, Warisa
Leepitakrat, Surachai
Insuan, Sucheera
Charoensongsermkit, Weerayut
Khlaimanee, Nittaya
Akkagraisee, Wilasinee
Chayapum, Kwanta
Jones, James W.
TI Surveys of rodent-borne disease in Thailand with a focus on scrub typhus
assessment
SO INTEGRATIVE ZOOLOGY
LA English
DT Article
DE GIS model; rodent-borne diseases; scrub typhus; surveillance surveys
AB The epidemiology of many rodent-borne diseases in South-East Asia remains ill-defined. Scrub typhus and leptospirosis are common and medically significant, while other zoonotic diseases, such as spotted fever group Rickettsiae have been identified, but their overall medical significance is unknown. Rodent surveillance was conducted from June 2002 to July 2004 in 18 provinces from Thailand. Traps were set up for one to three nights. Blood and serum samples and animal tissue samples (liver, spleen, kidney and urinary bladder) were collected. Chiggermites, ticks and fleas were removed from captured rodents. A total of 4536 wild-caught rodents from 27 species were captured over two years of animal trapping. Rattus rattus was the dominant species, followed by Rattus exulans and Bandicota indica. Almost 43 000 ectoparasites were removed from the captured animals. Approximately 98% of the ectoparasites were chigger-mites, of which 46% belonged to the genus Leptotrombidium (scrub typhus vector). Other genera included Schoengastia and Blankaartia. Tick and flea specimens together comprised less than 1% of the sample. Among the five species of ticks collected, Haemaphysalis bandicota was the predominant species caught, followed by Ixodes granulatus other Haemaphysalis spp., Rhipicephalus spp. and Dermacentor spp. Only two species of fleas were collected and Xenopsylla cheopis (rat flea) was the predominant species. Using both commercial diagnostic kits and in-house molecular assays, animal tissue samples were examined and screened for zoonotic diseases. Seven zoonotic diseases were detected: scrub typhus, leptospirosis, murine typhus, tick typhus, bartonella, babesiosis and trypanosomiasis. Most samples were positive for scrub typhus. Other zoonotic diseases still under investigation include borrelosis, ehrlichiosis, the plague, and other rickettsial diseases. Using geographic information systems, global positioning systems and remote sensing technology, epidemiological and environmental data were combined to assess the relative risk in different biotopes within highly endemic areas of scrub typhus in Thailand.
C1 [Lerdthusnee, Kriangkrai; Monkanna, Taweesak; Leepitakrat, Warisa; Leepitakrat, Surachai; Insuan, Sucheera; Charoensongsermkit, Weerayut; Khlaimanee, Nittaya; Akkagraisee, Wilasinee; Chayapum, Kwanta; Jones, James W.] Armed Forces Res Inst Med Sci, Dept Entomol, Bangkok 10400, Thailand.
[Nigro, Joseph] NASA, Goddard Space Flight Ctr, Greenbelt, MD 20771 USA.
RP Lerdthusnee, K (reprint author), Armed Forces Res Inst Med Sci, Dept Entomol, 315-6 Rajvithi Rd, Bangkok 10400, Thailand.
EM kriangkrail@afrims.org
FU US. Army Medical and Material Command, Fort Detrick, MD, USA
FX All animal procedures, field activities and experiments were conducted
under the strict guidelines of the Approved Animal Use-Protocols and
were approved by AFRIMS's Institutional Animal Care and Use Committee.
Funding for this project was provided by the Military Infectious
Diseases Research Program of the US. Army Medical and Material Command,
Fort Detrick, MD, USA. The views expressed in this paper are those of
the authors and do not purport to represent the position and/or reflect
the official policy of the Department of the Army, the Department of
Defense or the US Government.
NR 13
TC 12
Z9 14
U1 1
U2 15
PU WILEY-BLACKWELL PUBLISHING, INC
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1749-4877
J9 INTEGR ZOOL
JI Integr. Zool.
PD DEC
PY 2008
VL 3
IS 4
BP 267
EP 273
DI 10.1111/j.1749-4877.2008.00100.x
PG 7
WC Zoology
SC Zoology
GA V15GF
UT WOS:000207789800002
PM 21396076
ER
PT J
AU Hoover, NG
Heard, M
Reid, C
Wagoner, S
Rogers, K
Foland, J
Paden, ML
Fortenberry, JD
AF Hoover, Nancy G.
Heard, Michael
Reid, Christopher
Wagoner, Scott
Rogers, Kristine
Foland, Jason
Paden, Matthew L.
Fortenberry, James D.
TI Enhanced fluid management with continuous venovenous hemofiltration in
pediatric respiratory failure patients receiving extracorporeal membrane
oxygenation support
SO INTENSIVE CARE MEDICINE
LA English
DT Article
DE Respiratory failure; Continuous venovenous hemofiltration;
Extracorporeal; Hemofiltration; ECMO; Renal failure; Pediatrics;
Continuous renal replacement therapy
ID RENAL REPLACEMENT THERAPY; PULMONARY-EDEMA; HEARING-LOSS; ILL PATIENTS;
DETERMINANTS; CHILDREN; BALANCE
AB Background/purpose: Children receiving extracorporeal membrane oxygenation (ECMO) for respiratory failure can have significant fluid overload and renal insufficiency. Addition of inline continuous venovenous hemofiltration (CVVH) could provide additional benefits in fluid management compared to use of standard medical therapies with ECMO.
Methods: Patients with pediatric respiratory failure receiving ECMO with CVVH were case-matched to similar patients receiving ECMO without CVVH to compare fluid balance, medication use, and clinical outcomes.
Results: Twenty-six of eighty-six patients with pediatric respiratory failure on ECMO (30%) received CVVH for > 24 h (median 7.5 days on CVVH). Survival was not significantly different between patients receiving CVVH and those who did not receive CVVH (P = 0.51). For ECMO survivors receiving CVVH, overall fluid balance was less than that in non-CVVH survivors (median 25.1 ml kg(-1) stop day(-1); range -40.2 to 71.2 vs. 40.2, 1.1 to 134.9; P = 0.028). Time to desired caloric intake was faster in patients receiving CVVH (1 day, 1-5) than in patients who did not receive CVVH (5 days; 1-11; P < 0.001). Patients receiving CVVH-ECMO also received less furosemide (0.67 vs. 2.11 mg kg(-1) day (-1); P = 0.009).
Conclusions: Use of CVVH in ECMO was associated with improved fluid balance and caloric intake and less diuretics than in case-matched ECMO controls.
C1 [Paden, Matthew L.; Fortenberry, James D.] Childrens Healthcare Atlanta Egleston, Div Crit Care Med, Atlanta, GA 30322 USA.
[Hoover, Nancy G.] Walter Reed Army Med Ctr, Dept Pediat, Washington, DC 20307 USA.
[Paden, Matthew L.; Fortenberry, James D.] Emory Univ, Sch Med, Dept Pediat, Atlanta, GA USA.
[Heard, Michael; Reid, Christopher; Wagoner, Scott] Childrens Healthcare Atlanta Egleston, Div ECMO & Adv Technol, Atlanta, GA 30322 USA.
RP Fortenberry, JD (reprint author), Childrens Healthcare Atlanta Egleston, Div Crit Care Med, 1405 Clifton Rd NE, Atlanta, GA 30322 USA.
EM james.fortenberry@choa.org
NR 24
TC 48
Z9 49
U1 0
U2 4
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0342-4642
J9 INTENS CARE MED
JI Intensive Care Med.
PD DEC
PY 2008
VL 34
IS 12
BP 2241
EP 2247
DI 10.1007/s00134-008-1200-y
PG 7
WC Critical Care Medicine
SC General & Internal Medicine
GA 374SA
UT WOS:000261062800017
PM 18629472
ER
PT J
AU Nicolaides, A
Goldhaber, SZ
Maxwell, GL
Labropoulos, N
Clarke-Pearson, DL
Tyllis, TH
Griffin, MB
AF Nicolaides, A.
Goldhaber, S. Z.
Maxwell, G. L.
Labropoulos, N.
Clarke-Pearson, D. L.
Tyllis, T. H.
Griffin, M. B.
TI Cost benefit of intermittent pneumatic compression for venous
thromboembolism prophylaxis in general surgery
SO INTERNATIONAL ANGIOLOGY
LA English
DT Article
DE Venous thrombosis; Thromboembolism; Cost-benefit analysis
ID DEEP-VEIN THROMBOSIS; SUSPECTED PULMONARY-EMBOLISM; 3 SIMPLE DECISIONS;
DIAGNOSIS; PREVENTION; ULTRASOUND; GUIDELINES; MANAGEMENT; TRIAL
AB Aim. In moderate to high-risk general surgical patients, the cost effectiveness of mechanical prophylaxis for venous thromboembolism (VTE) is uncertain. Therefore, we determined the costs and savings of intermittent pneumatic compression (IPC) plus graduated compression stockings (GCS).
Methods. Postoperative VTE events in the absence of prophylaxis, efficacy of prophylaxis and costs of prophylaxis have been obtained from the English literature and Medicare 2004 reimbursement schedule.
Results. In 1000 moderate to high risk general surgical patients, in the absence of prophylaxis, the cost of investigating and treating 72 patients with clinical suspicion of DVT and 32 with PE is calculated to be $ 263 779. This corresponds to a cost of $ 263 per surgical patient. The cost of IPC combined with TED stockings in 1000 similar patients would be $ 66 760, and the cost of diagnosis and treatment of the reduced numbers (69% reduction) of clinical VTE is $ 83 574 making a total of $ 150 344. This means a saving of $ 133 435 ($ 263 779-$ 150 344) per 1 000 patients. This corresponds to a saving of $ 113 per surgical patient. Sensitivity analysis demonstrates that despite variation in costs or efficacy for IPC plus GCS, marked savings persist.
Conclusion. Prophylaxis with IPC not only prevents VTE but also saves money.
C1 [Nicolaides, A.; Tyllis, T. H.] Vasc Screening & Diagnost Ctr, CY-2368 Nicosia, Cyprus.
[Nicolaides, A.] Univ London Imperial Coll Sci Technol & Med, Dept Vasc Surg, London, England.
[Nicolaides, A.] Univ Cyprus, Dept Biol Sci, Nicosia, Cyprus.
[Goldhaber, S. Z.] Brigham & Womens Hosp, Div Cardiovasc, Boston, MA 02115 USA.
[Maxwell, G. L.] Walter Reed Army Med Ctr, Div Gynecol Oncol, Washington, DC 20307 USA.
[Labropoulos, N.] Univ Med & Dent New Jersey, Dept Vasc Surg, Newark, NJ 07103 USA.
[Labropoulos, N.] Univ Med & Dent New Jersey, Vasc Lab, Newark, NJ 07103 USA.
[Clarke-Pearson, D. L.] Univ N Carolina, Dept Obstet & Gynecol, Chapel Hill, NC USA.
[Griffin, M. B.] Vasc Screening & Diagnost Ctr, London, England.
RP Nicolaides, A (reprint author), Vasc Screening & Diagnost Ctr, 2 Ayios Dhometios, CY-2368 Nicosia, Cyprus.
EM anicolai@cytanet.com.cy
NR 36
TC 10
Z9 14
U1 0
U2 4
PU EDIZIONI MINERVA MEDICA
PI TURIN
PA CORSO BRAMANTE 83-85 INT JOURNALS DEPT., 10126 TURIN, ITALY
SN 0392-9590
EI 1827-1839
J9 INT ANGIOL
JI Int. Angiol.
PD DEC
PY 2008
VL 27
IS 6
BP 500
EP 506
PG 7
WC Peripheral Vascular Disease
SC Cardiovascular System & Cardiology
GA 410BZ
UT WOS:000263552200008
PM 19078913
ER
PT J
AU Huang, LH
Xie, J
Chen, RR
Chu, D
Chu, W
Hsu, AT
AF Huang, Lihong
Xie, Jian
Chen, Rongrong
Chu, Deryn
Chu, Wei
Hsu, Andrew T.
TI Effect of iron on durability of nickel-based catalysts in auto-thermal
reforming of ethanol for hydrogen production
SO INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
LA English
DT Article
DE Durability; Iron promoter; Nickel catalyst; Hydrogen production;
Auto-thermal reforming; Ethanol
ID BIO-ETHANOL; FUEL-CELL; SUPPORTED CATALYSTS; RH/AL2O3 CATALYST;
METAL-CATALYSTS; H-2 PRODUCTION; STEAM; NI; TEMPERATURE; PERFORMANCE
AB iron-promoted nickel-based catalysts were prepared by impregnation, tested in auto-thermal reforming (ATR) of ethanol for hydrogen production, and characterized by TPR, XRD, BET, TEM, and XPS. With the introduction of iron, mixed crystals of NiAl(2)O(4)-FeAl(2)O(4) spinel phase are formed, which results in modifications of its structural and electronic properties. The reaction results show a remarkable improvement on durability in catalytic activity as well as selectivity to hydrogen in ATR: over the 10 wt.% iron-loading nickel catalyst, conversion of ethanol at 99.61% and selectivity of hydrogen around 115% are kept at 600 degrees C during a 30-h test, while that of iron-free sample decreases sharply from 85.10% to 19.71% on hydrogen selectivity within a 26-h test. The improved durability is attributed to the synergistic effect of the NiAl(2)O(4)-FeAl(2)O(4) mixed crystals that are more resistant to sintering and oxidation in the oxidative atmosphere of ATR. (C) 2008 International Association for Hydrogen Energy. Published by Elsevier Ltd. All rights reserved.
C1 [Huang, Lihong; Xie, Jian; Chen, Rongrong; Chu, Wei; Hsu, Andrew T.] Indiana Univ Purdue Univ, Purdue Sch Engn & Technol, Lugar Ctr Renewable Energy, Indianapolis, IN 46202 USA.
[Chu, Deryn] USA, Res Lab, Adelphi, MD 20783 USA.
RP Hsu, AT (reprint author), Indiana Univ Purdue Univ, Purdue Sch Engn & Technol, Lugar Ctr Renewable Energy, 799 W Michigan St,ET 215, Indianapolis, IN 46202 USA.
EM anhsu@iupui.edu
RI Chu, Wei/I-4486-2013; Chu, Wei/C-6140-2011
OI Chu, Wei/0000-0002-7166-5443
FU U.S. Army Research Lab [W911NF-07-2-0036]
FX The research work is partially supported by the U.S. Army Research Lab
(Grant No. W911NF-07-2-0036). The authors wish to thank Dr. Jeffrey
Swope of Department of Geography Science at 1UPUI for XRD test, and to
Dr. Dmitry Zemlyanov of Birck Nanotechnology Center of Purdue University
for XPS characterizations, and acknowledge the useful discussions
provided by Drs. Muhua Chen, Dong Xie, Guigui Wang, Luhua Jiang and Mr.
Michael Reed.
NR 32
TC 32
Z9 32
U1 1
U2 7
PU PERGAMON-ELSEVIER SCIENCE LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
SN 0360-3199
J9 INT J HYDROGEN ENERG
JI Int. J. Hydrog. Energy
PD DEC
PY 2008
VL 33
IS 24
BP 7448
EP 7456
DI 10.1016/j.ijhydene.2008.09.062
PG 9
WC Chemistry, Physical; Electrochemistry; Energy & Fuels
SC Chemistry; Electrochemistry; Energy & Fuels
GA 389FX
UT WOS:000262077900017
ER
PT J
AU Alexander, CS
Chhabildas, LC
Reinhart, WD
Templeton, DW
AF Alexander, C. S.
Chhabildas, L. C.
Reinhart, W. D.
Templeton, D. W.
TI Changes to the shock response of fused quartz due to glass modification
SO INTERNATIONAL JOURNAL OF IMPACT ENGINEERING
LA English
DT Article; Proceedings Paper
CT 10th Hypervelocity Impact Symposium (HVIS 2007)
CY SEP 23-27, 2007
CL Williamsburg, VA
DE Shock; Glass; Random network model; Glass modifiers; Fused silica
ID SODA-LIME GLASS; WAVE COMPRESSION; STISHOVITE; BEHAVIOR; RELEASE
AB Silica based glasses are commonly used as window material in applications which are subject to high velocity impacts. Thorough understanding of the response to shock loading in these materials is crucial to the development of new designs. Despite the lack of long range order in amorphous glasses, the structure can be described statistically by the random network model. Changes to the network structure alter the response to shock loading. Results indicate that in fused silica, substitution of boron as a network former does not have a large effect on the shock loading properties while modifying the network with sodium and calcium changes the dynamic response. These initial results suggest the potential of a predictive capability to determine the effects of other network substitutions. Published by Elsevier Ltd.
C1 [Alexander, C. S.; Chhabildas, L. C.; Reinhart, W. D.] Sandia Natl Labs, Albuquerque, NM 87185 USA.
[Templeton, D. W.] US Army Tank Automot Res, Ctr Dev & Engn, Warren, MI 48397 USA.
RP Alexander, CS (reprint author), Sandia Natl Labs, Albuquerque, NM 87185 USA.
EM calexa@sandia.gov
NR 26
TC 37
Z9 39
U1 1
U2 12
PU PERGAMON-ELSEVIER SCIENCE LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
SN 0734-743X
J9 INT J IMPACT ENG
JI Int. J. Impact Eng.
PD DEC
PY 2008
VL 35
IS 12
BP 1376
EP 1385
DI 10.1016/j.ijimpeng.2008.07.019
PG 10
WC Engineering, Mechanical; Mechanics
SC Engineering; Mechanics
GA 392YQ
UT WOS:000262338500004
ER
PT J
AU McFarland, C
Papados, P
Giltrud, M
AF McFarland, C.
Papados, P.
Giltrud, M.
TI Hypervelocity impact penetration mechanics
SO INTERNATIONAL JOURNAL OF IMPACT ENGINEERING
LA English
DT Article; Proceedings Paper
CT 10th Hypervelocity Impact Symposium (HVIS 2007)
CY SEP 23-27, 2007
CL Williamsburg, VA
DE Penetration; Tungsten; Strength; Erosion; Limestone
AB Inert dense metal penetrators having a mass and geometry capable of missile delivery offer significant potential for countering underground facilities at depths of tens of meters in hard rock. The proliferation of such facilities among countries whose support for terrorism and potential possession of Weapons of Mass Destruction (WMD) constitutes threats to world peace and U.S. Security. The Defense Threat Reduction Agency (DTRA), in cooperation with the U.S. Army Corps of Engineers, the Department of Energy National Laboratories and private sector R&D firms have pursued an aggressive research effort to explore the attributes of high velocity impact penetrators for countering such facilities. The penetration of crustal rocks with metal rods (such as tungsten or steel alloys) at high velocities involves complex wave propagation phenomena within the rod and inelastic response of both the penetrator and target material. In this paper we examine the sensitivity of penetration depth (for a fixed tungsten alloy mass impacting a limestone target) to impactor velocity, strength and geometry. Analyses are based upon a matrix of first principle finite difference calculations using the Sandia CTH (release 7.1) Shock Physics Code. Results indicate that impact velocity, penetrator yield strength and target yield strength strongly influence the penetration depth. Maximum penetration depth is achieved by a delicate trade off between penetrator kinetic energy and penetrator inelastic deformation (erosion). Numerical analyses for the parameter variations exercised in this study (impact velocities 1-3.5 km/s and penetrator yield strengths of 1-4 GPa) produced penetration depths of a tungsten alloy rod (length 200 cm, diameter 20 cm) which varied from 5.1 m to 28 m in a homogeneous limestone target. (C) 2008 Elsevier Ltd. All rights reserved.
C1 [McFarland, C.] SAIC Inc, Alexandria, VA 22304 USA.
[Papados, P.] US Army Corps Engn, Engn Res & Dev Ctr, Alexandria, VA 22315 USA.
[Giltrud, M.] Def Threat Reduct Agcy, Ft Belvoir, VA 22060 USA.
RP McFarland, C (reprint author), SAIC Inc, 4875 Eisenhower Ave, Alexandria, VA 22304 USA.
EM clifton.b.mcfarland@saic.com
NR 10
TC 1
Z9 1
U1 2
U2 8
PU PERGAMON-ELSEVIER SCIENCE LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
SN 0734-743X
J9 INT J IMPACT ENG
JI Int. J. Impact Eng.
PD DEC
PY 2008
VL 35
IS 12
BP 1654
EP 1660
DI 10.1016/j.ijimpeng.2008.07.080
PG 7
WC Engineering, Mechanical; Mechanics
SC Engineering; Mechanics
GA 392YQ
UT WOS:000262338500046
ER
PT J
AU Raftenberg, MN
Mock, W
Kirby, GC
AF Raftenberg, M. N.
Mock, W., Jr.
Kirby, G. C.
TI Modeling the impact deformation of rods of a pressed PTFE/Al composite
mixture
SO INTERNATIONAL JOURNAL OF IMPACT ENGINEERING
LA English
DT Article; Proceedings Paper
CT 10th Hypervelocity Impact Symposium (HVIS 2007)
CY SEP 23-27, 2007
CL Williamsburg, VA
DE Polytetrafluoroethylene; PTFE/Al; Split Hopkinson bar; Taylor anvil;
Johnson-Cook strength
AB Finite element simulations have been performed for the impact onto steel anvils of solid rods of a pressed composite mixture of polytetrafluoroethylene (PTFE) and aluminum powders. Photographs of the reactive rods prior to significant impact initiation for three previously performed experiments at impact velocities of 104, 222, and 466 m/s have been digitized for comparison with the simulations Simulations. were performed using the Johnson-Cook and PSDam strength models Parameters for the PSDam model. have been previously determined for this PTFE/Al mixture. The results of Instron compression tests and high-rate slit Hopkinson bar experiments were used to determine the parameters for the Johnson-Cook model. The Johnson-Cook model produced reasonable agreement with the experimental specimen shape at 104 m/s. PSDam produced reasonable agreement at early times for the 222 m/s experiment. Published by Elsevier Ltd.
C1 [Raftenberg, M. N.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
[Mock, W., Jr.; Kirby, G. C.] USN, Ctr Surface Warfare, Dahlgren Div, Dahlgren, VA 22448 USA.
RP Raftenberg, MN (reprint author), USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
EM mnr@arl.army.mil
NR 11
TC 16
Z9 26
U1 8
U2 34
PU PERGAMON-ELSEVIER SCIENCE LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
SN 0734-743X
J9 INT J IMPACT ENG
JI Int. J. Impact Eng.
PD DEC
PY 2008
VL 35
IS 12
BP 1735
EP 1744
DI 10.1016/j.ijimpeng.2008.07.041
PG 10
WC Engineering, Mechanical; Mechanics
SC Engineering; Mechanics
GA 392YQ
UT WOS:000262338500059
ER
PT J
AU Sorensen, BR
Kimsey, KD
Love, BM
AF Sorensen, B. R.
Kimsey, K. D.
Love, B. M.
TI High-velocity impact of low-density projectiles on structural aluminum
armor
SO INTERNATIONAL JOURNAL OF IMPACT ENGINEERING
LA English
DT Article; Proceedings Paper
CT 10th Hypervelocity Impact Symposium (HVIS 2007)
CY SEP 23-27, 2007
CL Williamsburg, VA
DE Hypervelocity impact; KE projectiles; Low-density projectiles; Aluminum
armor
ID LONG-ROD PENETRATION; MODEL
AB The US Army Research Laboratory has been studying the impact physics of low-density projectiles on urban and light-armor structures for use in electro-magnetic cannons. In this paper, results of low-aspect ratio projectiles of nylon, aluminum and steel impacting aluminum armor at velocities above 2000 m/s will be presented. Both computational solid mechanics and analytic modeling techniques were used to supplement experiments to derive a toolkit for assessing target response and character of the debris created from different constant energy impact conditions. Published by Elsevier Ltd.
C1 [Sorensen, B. R.; Kimsey, K. D.; Love, B. M.] USA, Res Lab, AMSRD ARL WM TC, Aberdeen Proving Ground, MD 21005 USA.
RP Sorensen, BR (reprint author), USA, Res Lab, AMSRD ARL WM TC, Aberdeen Proving Ground, MD 21005 USA.
EM sorensen@arl.army.mil
NR 7
TC 6
Z9 6
U1 1
U2 8
PU PERGAMON-ELSEVIER SCIENCE LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
SN 0734-743X
J9 INT J IMPACT ENG
JI Int. J. Impact Eng.
PD DEC
PY 2008
VL 35
IS 12
BP 1808
EP 1815
DI 10.1016/j.ijimpeng.2008.07.077
PG 8
WC Engineering, Mechanical; Mechanics
SC Engineering; Mechanics
GA 392YQ
UT WOS:000262338500068
ER
PT J
AU Garcon, N
Van Mechelen, M
Leroux-Roels, G
Stanberry, L
Osterhaus, A
Heppner, G
Kester, KE
Polhemus, M
Horsmans, Y
Cohen, J
AF Garcon, N.
Van Mechelen, M.
Leroux-Roels, G.
Stanberry, L.
Osterhaus, A.
Heppner, G.
Kester, K. E.
Polhemus, M.
Horsmans, Y.
Cohen, J.
TI Vaccines Adjuvanted with Adjuvant Systems - from Concept to Clinical
Evidence
SO INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
LA English
DT Meeting Abstract
C1 [Garcon, N.; Van Mechelen, M.; Cohen, J.] GlaxoSmithKline Biol, Rixensart, 10027, Belgium.
[Leroux-Roels, G.] Ghent Univ & Hosp, Ctr Vaccinol, Ghent, Belgium.
[Stanberry, L.] Columbia Univ, Dept Pediat, New York, NY USA.
[Osterhaus, A.] Erasmus MC, Dept Virol, Rotterdam, Netherlands.
[Heppner, G.; Kester, K. E.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Polhemus, M.] Walter Reed Project, Kisumu, Kenya.
[Horsmans, Y.] St Luc Univ Hosp, Brussels, Belgium.
RI Kester, Kent/A-2114-2011
OI Kester, Kent/0000-0002-5056-0802
NR 0
TC 0
Z9 0
U1 0
U2 0
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1201-9712
J9 INT J INFECT DIS
JI Int. J. Infect. Dis.
PD DEC
PY 2008
VL 12
SU 1
BP E151
EP E151
DI 10.1016/j.ijid.2008.05.374
PG 1
WC Infectious Diseases
SC Infectious Diseases
GA 406II
UT WOS:000263287800373
ER
PT J
AU Klein, T
Baek, L
Kim, H
O'Guinn, M
Lee, J
Turell, M
Richards, A
Sames, W
Chong, S
Graf, P
Song, J
AF Klein, T.
Baek, L.
Kim, H.
O'Guinn, M.
Lee, J.
Turell, M.
Richards, A.
Sames, W.
Chong, S.
Graf, P.
Song, J.
TI Rodent-borne Disease Surveillance at US Military Training Sites Near the
Demilitarized Zone, Republic of Korea
SO INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
LA English
DT Meeting Abstract
C1 [Klein, T.; Kim, H.; Chong, S.] 18th Med Command, Seoul, South Korea.
[Baek, L.; Song, J.] Korea Univ, Dept Microbiol, Seoul, South Korea.
[O'Guinn, M.; Lee, J.; Turell, M.] USA, Med Res Inst Infect Dis, Dept Virol, Frederick, MD USA.
[Richards, A.; Graf, P.] Dept Naval Med Res Ctr, Silver Spring, MD USA.
[Sames, W.] Def Logist Agcy, Ft Belvoir, VA USA.
NR 0
TC 0
Z9 0
U1 2
U2 2
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1201-9712
J9 INT J INFECT DIS
JI Int. J. Infect. Dis.
PD DEC
PY 2008
VL 12
BP E86
EP E86
DI 10.1016/j.ijid.2008.05.214
PG 1
WC Infectious Diseases
SC Infectious Diseases
GA 406II
UT WOS:000263287800213
ER
PT J
AU Kalb, SR
Smith, TJ
Moura, H
Hill, K
Lou, JL
Geren, IN
Garcia-Rodriguez, C
Marks, JD
Smith, LA
Pirkle, JL
Barr, JR
AF Kalb, Suzanne R.
Smith, Theresa J.
Moura, Hercules
Hill, Karen
Lou, Jianlong
Geren, Isin N.
Garcia-Rodriguez, Consuelo
Marks, James D.
Smith, Leonard A.
Pirkle, James L.
Barr, John R.
TI The use of Endopep-MS to detect multiple subtypes of botulinum
neurotoxins A, B, E, and F
SO INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
LA English
DT Article
DE Botulinum neurotoxin; Botulism; Mass spectrometry
ID CLOSTRIDIUM-BOTULINUM; NUCLEOTIDE-SEQUENCE; MASS-SPECTROMETRY; INFANT
BOTULISM; BINDING DOMAIN; ANTIBODY; TOXIN; GENE; STRAINS; CHAIN
AB Botulinum neurotoxins (BoNTs) cause the disease botulism, which can be lethal if untreated. Rapid determination of exposure to BoNT is an important public health goal. Previous work in our laboratory focused on the development of Endopep-MS, a mass spectrometry-based endopeptidase method for detecting and differentiating BoNT A-G in buffer and BoNT A, B, E, and F in clinical samples. We introduce here the use of Endeopep-MS to detect non-commercial subtypes of BoNT A, B, E, and F which have been associated with botulism outbreaks. We have now tested and successfully detected 15 of the 17 known subtypes of BoNT A, B, E, and F by Endopep-MS. Extraction of BoNT A and B from a complex mixture prior to analysis is accomplished by using monoclonal antibodies specific for the catalytically inactive heavy chain of the toxin. These antibodies have high-binding affinities and do not interfere with the catalytic activity of the light chain resulting in a lower limit of detection for BoNT A and B than previously reported. We also report for the first time limits of detection for BoNT A2, A3, B2, and bivalent B using Endopep-MS. Published by Elsevier B.V.
C1 [Kalb, Suzanne R.; Moura, Hercules; Pirkle, James L.; Barr, John R.] Ctr Dis Control & Prevent, NCEH, DLS, Atlanta, GA 30341 USA.
[Smith, Theresa J.; Smith, Leonard A.] USA, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA.
[Hill, Karen] Los Alamos Natl Lab, Biosci Div, Los Alamos, NM 87545 USA.
[Lou, Jianlong; Geren, Isin N.; Garcia-Rodriguez, Consuelo; Marks, James D.] Univ Calif San Francisco, San Francisco Gen Hosp, Dept Anesthesia & Pharmaceut Chem, San Francisco, CA 94110 USA.
RP Barr, JR (reprint author), Ctr Dis Control & Prevent, NCEH, DLS, 4770 Buford Highway NE,Mailstop F-44, Atlanta, GA 30341 USA.
EM jbarr@cdc.gov
FU NIAID cooperative [U01 A1056493, 200-2006-16697]; CDC [200-2006-16697]
FX The authors acknowledge several funding sources for the production of
monoclonal antibodies: NIAID cooperative agreement U01 A1056493 (JDM),
DoD contract DAMD17-03-C-0076 UDM), UC MEXUS-CONACYT Faculty Visit
Fellowship (CG), and CDC contract 200-2006-16697 UDM).
NR 33
TC 29
Z9 29
U1 1
U2 6
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 1387-3806
J9 INT J MASS SPECTROM
JI Int. J. Mass Spectrom.
PD DEC 1
PY 2008
VL 278
IS 2-3
BP 101
EP 108
DI 10.1016/j.ijms.2008.04.004
PG 8
WC Physics, Atomic, Molecular & Chemical; Spectroscopy
SC Physics; Spectroscopy
GA 378EM
UT WOS:000261304000002
ER
PT J
AU Keller, CB
AF Keller, Christian B.
TI Counter-Thrust: From the Peninsula to the Antietam.
SO JOURNAL OF AMERICAN HISTORY
LA English
DT Book Review
C1 [Keller, Christian B.] USA, Command & Gen Staff Coll, Ft Belvoir, VA 22060 USA.
RP Keller, CB (reprint author), USA, Command & Gen Staff Coll, Ft Belvoir, VA 22060 USA.
NR 1
TC 0
Z9 0
U1 0
U2 0
PU ORGANIZATION AMER HISTORIANS
PI BLOOMINGTON
PA 112 N BRYAN ST, BLOOMINGTON, IN 47408 USA
SN 0021-8723
J9 J AM HIST
JI J. Am. Hist.
PD DEC
PY 2008
VL 95
IS 3
BP 857
EP 858
PG 2
WC History
SC History
GA 383GC
UT WOS:000261661100064
ER
PT J
AU Andrade, D
AF Andrade, Dale
TI Vietnam's Forgotten Army: Heroism and Betrayal in the ARVN
SO JOURNAL OF AMERICAN HISTORY
LA English
DT Book Review
C1 [Andrade, Dale] USA, Ctr Mil Hist, Washington, DC 20310 USA.
RP Andrade, D (reprint author), USA, Ctr Mil Hist, Washington, DC 20310 USA.
NR 1
TC 0
Z9 0
U1 0
U2 0
PU ORGANIZATION AMER HISTORIANS
PI BLOOMINGTON
PA 112 N BRYAN ST, BLOOMINGTON, IN 47408 USA
SN 0021-8723
J9 J AM HIST
JI J. Am. Hist.
PD DEC
PY 2008
VL 95
IS 3
BP 918
EP 919
PG 2
WC History
SC History
GA 383GC
UT WOS:000261661100135
ER
PT J
AU Chen, Y
Farrell, S
Brill, G
Wijewarnasuriya, P
Dhar, N
AF Chen, Y.
Farrell, S.
Brill, G.
Wijewarnasuriya, P.
Dhar, N.
TI Dislocation reduction in CdTe/Si by molecular beam epitaxy through
in-situ annealing
SO JOURNAL OF CRYSTAL GROWTH
LA English
DT Article
DE Dislocation; Molecular beam epitaxy; CdTe; HgCdTe; Si; Etched pit
density; Annealing
ID DENSITY REDUCTION; INFRARED HGCDTE; MBE GROWTH; SILICON; DETECTORS;
CDZNTE; ZNTE
AB The relatively high dislocation density of HgCdTe material grown on CdTe/Si by MBE has become a major roadblock toward achieving high operability of LWIR HgCdTe/Si FPAs. One approach to mitigate this problem is to reduce the dislocation density of the underlying CdTe/Si composite substrate, which is currently about two orders higher than that of bulk CdZnTe. In this paper, we will report on our systematic study of in-situ cyclic annealing of CdTe/Si and its impact on dislocation density. We observed a two orders of magnitude reduction of dislocation density on in-situ annealed CdTe/Si with respect to un-annealed CdTe/Si. The degree of reduction is proportional to the number of annealing cycles applied during the growth run. Depth profiling of the dislocation density of CdTe/Si layers with and without in-situ cyclic annealing has also been investigated. We do not observe the conventional 1/h behavior of the dislocation density for layers grown without any thermal treatment. In contrast, for the layer grown with in-situ cyclic annealing, we observe an exponential decay of dislocation density as a function of layer thickness. However, we also observe a saturation of dislocation density in low to mid 10(5) cm(-2), regardless of the annealing temperature and number of the cycles used during annealing. Published by Elsevier B.V.
C1 [Chen, Y.; Brill, G.; Wijewarnasuriya, P.; Dhar, N.] USA, Res Lab, Adelphi, MD 20783 USA.
[Farrell, S.] George Mason Univ, Dept Elect & Comp Engn, Fairfax, VA 22030 USA.
RP Chen, Y (reprint author), USA, Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM yuanping.chen@us.army.mil
RI Brill, Gregory/G-4877-2013
FU Penn State Electro-Optics Center [N00024-02-D-6604]; Army Research
Office [W911NF-07-2-0055]
FX Authors would like to thank J. G. Tischler at Naval Research Laboratory
for measuring low-temperature photoluminescence on our samples. One of
us, Mr. Stuart Farrell, would like to acknowledge helpful discussions
with Prof. Mulpuri at George Mason University and financial support
provided by Penn State Electro-Optics Center under contract
N00024-02-D-6604 and Army Research Office under grant W911NF-07-2-0055.
NR 16
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U1 2
U2 12
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0022-0248
J9 J CRYST GROWTH
JI J. Cryst. Growth
PD DEC 1
PY 2008
VL 310
IS 24
BP 5303
EP 5307
DI 10.1016/j.jcrysgro.2008.09.023
PG 5
WC Crystallography; Materials Science, Multidisciplinary; Physics, Applied
SC Crystallography; Materials Science; Physics
GA 390WH
UT WOS:000262193900012
ER
PT J
AU Bernier-Rodriguez, JA
Sidow, SJ
Joyce, AP
McNally, K
McPherson, JC
AF Bernier-Rodriguez, Joseph A.
Sidow, Stephanie J.
Joyce, Anthony P.
McNally, Kathleen
McPherson, James C., III
TI Radiographic Interpretation of Experimental Lesions in Radicular Tooth
Structure of Human Maxillary Anterior Teeth
SO JOURNAL OF ENDODONTICS
LA English
DT Article
DE External resorption; radicular; radiograph; radiographic detection
ID BONY LESIONS; PERIAPICAL LESIONS
AB External resorption is often first detected radiographically. Early detection can lead to timely intervention and improvement of treatment outcome. The purpose of this study was to determine the minimal radicular defect size in maxillary anterior teeth that is radiographically detectable. Six teeth were selected in a cadaver maxilla (#6-11) and extracted. The teeth were then replanted in the maxilla, and three horizontally angled radiographs (0 degrees, 30 degrees from the mesial, and 30 degrees from the distal) were exposed as a baseline. Then, a sequence of tooth removal, placement of a 0.1-mm deep defect in the interproximal and midroot surface, tooth replantation, and radiograph exposure was begun and repeated eight times. Each time the defect depth was increased by 0.1 mm. Ten clinicians interpreted the subsequent radiographs to determine if they visualized a defect on each tooth and the location of the defect. The evaluators' ability to detect experimental lesions according to the depth of the defect was shown to be statistically significant for both tooth type and location of the radicular defect (analysis of variance, p < 0.05). The average size of defect needed for radiographic visualization was as follows: central incisor (0.28 mm on the interproximal [IP] and 0.74 mm on the midroot [MR] [palatal], lateral incisor (0.39 mm on the IP and 0.55 mm on the MR); and canine [0.45 mm on the IP and 0.71 mm on the MR). Based on the results of this study, the minimal defect size detected was 0.28 mm to 0.74 mm depending on defect location and tooth selected. (J Endod 2008;34:1466-1469)
C1 [Bernier-Rodriguez, Joseph A.; Sidow, Stephanie J.; McNally, Kathleen] USA, Endodont Residency Program, Ft Gordon, GA USA.
[Joyce, Anthony P.] USA, Dent Activ, Schofield Barracks, HI USA.
[McPherson, James C., III] USA, Dept Clin Invest, Ft Gordon, GA USA.
RP Bernier-Rodriguez, JA (reprint author), Ft Campbell Dent Act, 2441 21st St, Ft Campbell, KY 42223 USA.
EM joseph.bernier@us.army.mil
NR 24
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U1 0
U2 0
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0099-2399
J9 J ENDODONT
JI J. Endod.
PD DEC
PY 2008
VL 34
IS 12
BP 1466
EP 1469
DI 10.1016/j.joen.2008.09.009
PG 4
WC Dentistry, Oral Surgery & Medicine
SC Dentistry, Oral Surgery & Medicine
GA 382RN
UT WOS:000261623200007
PM 19026875
ER
PT J
AU Davis, RE
Painter, TH
Cline, D
Armstrong, R
Haran, T
McDonald, K
Forster, R
Elder, K
AF Davis, Robert E.
Painter, Thomas H.
Cline, Don
Armstrong, Richard
Haran, Terry
McDonald, Kyle
Forster, Rick
Elder, Kelly
TI NASA Cold Land Processes Experiment (CLPX 2002/03): Spaceborne Remote
Sensing
SO JOURNAL OF HYDROMETEOROLOGY
LA English
DT Article
ID SNOW WATER EQUIVALENT; THEMATIC MAPPER; GRAIN-SIZE; COVER; RESOLUTION;
RETRIEVAL
AB This paper describes satellite data collected as part of the 2002/03 Cold Land Processes Experiment (CLPX). These data include multispectral and hyperspectral optical imaging, and passive and active microwave observations of the test areas. The CLPX multispectral optical data include the Advanced Very High Resolution Radiometer (AVHRR), the Landsat Thematic Mapper/Enhanced Thematic Mapper Plus (TM/ETM +), the Moderate Resolution Imaging Spectroradiometer ( MODIS), and the Multi-angle Imaging Spectroradiometer (MISR). The spaceborne hyperspectral optical data consist of measurements acquired with the NASA Earth Observing-1 (EO-1) Hyperion imaging spectrometer. The passive microwave data include observations from the Special Sensor Microwave Imager (SSM/I) and the Advanced Microwave Scanning Radiometer (AMSR) for Earth Observing System (EOS; AMSR-E). Observations from the Radarsat synthetic aperture radar and the SeaWinds scatterometer flown on QuikSCAT make up the active microwave data.
C1 [Davis, Robert E.] USACE, Cold Reg Res & Engn Lab, Hanover, NH 03755 USA.
[Painter, Thomas H.; Forster, Rick] Univ Utah, Dept Geog, Salt Lake City, UT USA.
[Cline, Don] Natl Weather Serv, Natl Operat Remote Sensing Hydrol Ctr, Chanhassen, MN USA.
[Armstrong, Richard; Haran, Terry] Univ Colorado, Natl Snow & Ice Data Ctr, Boulder, CO 80309 USA.
[McDonald, Kyle] CALTECH, Jet Prop Lab, Pasadena, CA USA.
[Elder, Kelly] US Forest Serv, Rocky Mt Res Stn, USDA, Ft Collins, CO USA.
RP Davis, RE (reprint author), USACE, Cold Reg Res & Engn Lab, 72 Lyme Rd, Hanover, NH 03755 USA.
EM robert.e.davis@erdc.usace.army.mil
RI Painter, Thomas/B-7806-2016
FU National Aeronautics and Space Administration (NASA) Earth Science
Enterprise; Terrestrial Hydrology Program; Earth Observing System
Program; Airborne Science Program; National Oceanic and Atmospheric
Administration Office of Global Programs; U. S. Army Corps of Engineers
Civil Works Remote Sensing Research Program; the U. S. Army Basic
Research Program; National Space Development Agency of Japan (NASDA);
Japan Science and Technology Corporation; National Assembly for Wales;
Science Research Investment Fund; Cardiff University; Jet Propulsion
Laboratory at the California Institute of Technology
FX This work was funded through the cooperation of many agencies and
organizations including the National Aeronautics and Space
Administration (NASA) Earth Science Enterprise, Terrestrial Hydrology
Program, Earth Observing System Program, and Airborne Science Program;
the National Oceanic and Atmospheric Administration Office of Global
Programs; the U. S. Army Corps of Engineers Civil Works Remote Sensing
Research Program; the U. S. Army Basic Research Program; the National
Space Development Agency of Japan (NASDA); the Japan Science and
Technology Corporation; and the National Assembly for Wales, Science
Research Investment Fund, Cardiff University. A portion of this work was
conducted at the Jet Propulsion Laboratory at the California Institute
of Technology, under contract to NASA. More than 200 people participated
in the planning and execution of CLPX 2002/03. Their efforts are very
much appreciated. We would also like to thank the two anonymous and
thorough reviewers who helped to improve the manuscript.
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PU AMER METEOROLOGICAL SOC
PI BOSTON
PA 45 BEACON ST, BOSTON, MA 02108-3693 USA
SN 1525-755X
J9 J HYDROMETEOROL
JI J. Hydrometeorol.
PD DEC
PY 2008
VL 9
IS 6
BP 1427
EP 1433
DI 10.1175/2008JHM926.1
PG 7
WC Meteorology & Atmospheric Sciences
SC Meteorology & Atmospheric Sciences
GA 386DD
UT WOS:000261861600019
ER
PT J
AU Hardy, J
Davis, R
Koh, Y
Cline, D
Elder, K
Armstrong, R
Marshall, HP
Painter, T
Saint-Martin, GC
Deroo, R
Sarabandi, K
Graf, T
Koike, T
McDonald, K
AF Hardy, Janet
Davis, Robert
Koh, Yeohoon
Cline, Don
Elder, Kelly
Armstrong, Richard
Marshall, Hans-Peter
Painter, Thomas
Saint-Martin, Gilles Castres
Deroo, Roger
Sarabandi, Kamal
Graf, Tobias
Koike, Toshio
McDonald, Kyle
TI NASA Cold Land Processes Experiment (CLPX 2002/03): Local Scale
Observation Site
SO JOURNAL OF HYDROMETEOROLOGY
LA English
DT Article
AB The local scale observation site (LSOS) is the smallest study site (0.8 ha) of the 2002/03 Cold Land Processes Experiment (CLPX) and is located within the Fraser mesocell study area. It was the most intensively measured site of the CLPX, and measurements here had the greatest temporal component of all CLPX sites. Measurements made at the LSOS were designed to produce a comprehensive assessment of the snow, soil, and vegetation characteristics viewed by the ground-based remote sensing instruments. The objective of the ground-based microwave remote sensing was to collect time series of active and passive microwave spectral signatures over snow, soil, and forest, which is coincident with the intensive physical characterization of these features. Ground-based remote sensing instruments included frequency modulated continuous wave (FMCW) radars operating over multiple microwave bandwidths; the Ground-Based Microwave Radiometer (GBMR-7) operating at channels 18.7, 23.8, 36.5, and 89 GHz; and in 2003, an L-, C-, X- and Ku-band scatterometer radar system. Snow and soil measurements included standard snow physical properties, snow wetness, snow depth transects, and soil moisture. The stem and canopy temperature and xylem sap flux of several trees were monitored continuously. Five micrometeorological towers monitored ambient conditions and provided forcing datasets for 1D snow and soil models. Arrays of pyranometers (0.3-3 mu m) and a scanning thermal radiometer (8-12 mu m) characterized the variability of radiative receipt in the forests. A field spectroradiometer measured the hyperspectral hemispherical-directional reflectance of the snow surface. These measurements, together with the ground-based remote sensing, provide the framework for evaluating and improving microwave radiative transfer models and coupling them to land surface models. The dataset is archived at the National Snow and Ice Data Center (NSIDC) in Boulder, Colorado.
C1 [Hardy, Janet; Davis, Robert; Koh, Yeohoon] US Army Corps Engineers, Engn Res & Dev Ctr, CRREL, Hanover, NH 03755 USA.
[Cline, Don] NOAA, NWS, Natl Operat Hydrol Remote Sensing Ctr, Chanhassen, MN USA.
[Elder, Kelly] US Forest Serv, USDA, Ft Collins, CO USA.
[Armstrong, Richard; Marshall, Hans-Peter] Univ Colorado, Boulder, CO 80309 USA.
[Painter, Thomas] Univ Utah, Salt Lake City, UT USA.
[Saint-Martin, Gilles Castres; Deroo, Roger; Sarabandi, Kamal] Univ Michigan, Ann Arbor, MI 48109 USA.
[Graf, Tobias; Koike, Toshio] Univ Tokyo, Tokyo, Japan.
[McDonald, Kyle] CALTECH, Jet Prop Lab, NASA, Pasadena, CA USA.
RP Hardy, J (reprint author), US Army Corps Engineers, Engn Res & Dev Ctr, CRREL, 72 Lyme Rd, Hanover, NH 03755 USA.
EM janet.p.hardy@usace.army.mil
RI Marshall, Hans-Peter/A-2374-2010; De Roo, Roger/J-2208-2012; Painter,
Thomas/B-7806-2016
OI Marshall, Hans-Peter/0000-0002-4852-5637; De Roo,
Roger/0000-0001-8391-2950;
FU National Aeronautics and Space Administration (NASA); U. S. Army Corps
of Engineers Civil Works Remote Sensing Research Program; U. S. Army
Basic Research Program; Japan Aerospace Exploration Agency (JAXA); Japan
Science and Technology Agency; National Assembly for Wales; Strategic
Research Investment Fund, Cardiff; Jet Propulsion Laboratory at the
California Institute of Technology
FX This work was funded through cooperation of many agencies and
organizations including the National Aeronautics and Space
Administration (NASA), the U. S. Army Corps of Engineers Civil Works
Remote Sensing Research Program, the U. S. Army Basic Research Program,
the Japan Aerospace Exploration Agency (JAXA), the Japan Science and
Technology Agency, and the National Assembly for Wales, Strategic
Research Investment Fund, Cardiff. A portion of this work was conducted
at the Jet Propulsion Laboratory at the California Institute of
Technology, under contract to NASA.
NR 12
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Z9 8
U1 0
U2 5
PU AMER METEOROLOGICAL SOC
PI BOSTON
PA 45 BEACON ST, BOSTON, MA 02108-3693 USA
SN 1525-755X
J9 J HYDROMETEOROL
JI J. Hydrometeorol.
PD DEC
PY 2008
VL 9
IS 6
BP 1434
EP 1442
DI 10.1175/2008JHM875.1
PG 9
WC Meteorology & Atmospheric Sciences
SC Meteorology & Atmospheric Sciences
GA 386DD
UT WOS:000261861600020
ER
PT J
AU Frankenstein, S
Sawyer, A
Koeberle, J
AF Frankenstein, Susan
Sawyer, Anne
Koeberle, Julie
TI Comparison of FASST and SNTHERM in Three Snow Accumulation Regimes
SO JOURNAL OF HYDROMETEOROLOGY
LA English
DT Article
ID ENERGY-BALANCE; BOREAL FOREST; STAND-SCALE; MODEL; COVER; ABLATION;
BASIN; HEAT; PARAMETERIZATION; SIMULATION
AB Numerical experiments of snow accumulation and depletion were carried out as well as surface energy fluxes over four Cold Land Processes Experiment (CLPX) sites in Colorado using the Snow Thermal model (SNTHERM) and the Fast All-Season Soil Strength model (FASST). SNTHERM is a multilayer snow model developed to describe changes in snow properties as a function of depth and time, using a one-dimensional mass and energy balance. The model is intended for seasonal snow covers and addresses conditions found throughout the winter, from initial ground freezing in the fall to snow ablation in the spring. It has been used by many researchers over a variety of terrains. FASST is a newly developed one-dimensional dynamic state-of-the-ground model. It calculates the ground's moisture content, ice content, temperature, and freeze-thaw profiles as well as soil strength and surface ice and snow accumulation/depletion. Because FASST is newer and not as well known, the authors wanted to determine its use as a snow model by comparing it with SNTHERM, one of the most established snow models available. It is demonstrated that even though FASST is only a single-layer snow model, the RMSE snow depth compared very favorably against SNTHERM, often performing better during the accumulation phase. The surface energy fluxes calculated by the two models were also compared and were found to be similar.
C1 [Frankenstein, Susan] USA, ERDC CRREL, Hanover, NH 03755 USA.
[Sawyer, Anne] NOAA NWS NOHRSC, Chanhassen, MN USA.
[Koeberle, Julie] Natl Resources Conservat Serv, Snow Survey Off, USDA, Boise, ID USA.
RP Frankenstein, S (reprint author), USA, ERDC CRREL, 72 Lyme Rd, Hanover, NH 03755 USA.
EM susan.frankenstein@erdc.usace.army.mil
NR 37
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U1 1
U2 8
PU AMER METEOROLOGICAL SOC
PI BOSTON
PA 45 BEACON ST, BOSTON, MA 02108-3693 USA
SN 1525-755X
J9 J HYDROMETEOROL
JI J. Hydrometeorol.
PD DEC
PY 2008
VL 9
IS 6
BP 1443
EP 1463
DI 10.1175/2008JHM865.1
PG 21
WC Meteorology & Atmospheric Sciences
SC Meteorology & Atmospheric Sciences
GA 386DD
UT WOS:000261861600021
ER
PT J
AU Pomeroy, J
Rowlands, A
Hardy, J
Link, T
Marks, D
Essery, R
Sicart, JE
Ellis, C
AF Pomeroy, John
Rowlands, Aled
Hardy, Janet
Link, Tim
Marks, Danny
Essery, Richard
Sicart, Jean Emmanuel
Ellis, Chad
TI Spatial Variability of Shortwave Irradiance for Snowmelt in Forests
SO JOURNAL OF HYDROMETEOROLOGY
LA English
DT Article
ID BOREAL FOREST; THEORETICAL ANALYSIS; COVER DEPLETION; ENERGY-BALANCE;
MELT RATE; CANOPY; RADIATION; ABLATION; STANDS; MODEL
AB The spatial variation of melt energy can influence snow cover depletion rates and in turn be influenced by the spatial variability of shortwave irradiance to snow. The spatial variability of shortwave irradiance during melt under uniform and discontinuous evergreen canopies at a U. S. Rocky Mountains site was measured, analyzed, and then compared to observations from mountain and boreal forests in Canada. All observations used arrays of pyranometers randomly spaced under evergreen canopies of varying structure and latitude. The spatial variability of irradiance for both overcast and clear conditions declined dramatically, as the sample averaging interval increased from minutes to 1 day. At daily averaging intervals, there was little influence of cloudiness on the variability of subcanopy irradiance; instead, it was dominated by stand structure. The spatial variability of irradiance on daily intervals was higher for the discontinuous canopies, but it did not scale reliably with canopy sky view. The spatial variation in irradiance resulted in a coefficient of variation of melt energy of 0.23 for the set of U. S. and Canadian stands. This variability in melt energy smoothed the snow-covered area depletion curve in a distributed melt simulation, thereby lengthening the duration of melt by 20%. This is consistent with observed natural snow cover depletion curves and shows that variations in melt energy and snow accumulation can influence snow-covered area depletion under forest canopies.
C1 [Pomeroy, John; Ellis, Chad] Univ Saskatchewan, Ctr Hydrol, Saskatoon, SK S7N 5CB, Canada.
[Rowlands, Aled; Essery, Richard] Univ Wales, Inst Geog & Earth Sci, Aberystwyth, Ceredigion, Wales.
[Hardy, Janet] USA, Cold Reg Res & Engn Lab, Hanover, NH 03755 USA.
[Link, Tim] Univ Idaho, Dept Forest Resources, Moscow, ID 83843 USA.
[Marks, Danny] Agr Res Serv, NW Watershed Res Ctr, USDA, Boise, ID USA.
[Sicart, Jean Emmanuel] Inst Rech Dev, Montpellier, France.
RP Pomeroy, J (reprint author), Univ Saskatchewan, Ctr Hydrol, 117 Sci Pl, Saskatoon, SK S7N 5CB, Canada.
EM john.pomeroy@usask.ca
RI Link, Timothy/G-5556-2012; Pomeroy, John/A-8589-2013;
OI Pomeroy, John/0000-0002-4782-7457; Essery, Richard/0000-0003-1756-9095
FU NOAA GEWEX Americas Prediction Project (GAPP); U. S. Army Corps of
Engineers; Cold Regions Research and Engineering Laboratory; USDA
Agricultural Research Service; Canadian Foundation for Climate and
Atmospheric Sciences; Natural Sciences and Engineering Research Council
of Canada
FX The financial support of the NOAA GEWEX Americas Prediction Project
(GAPP), U. S. Army Corps of Engineers, Cold Regions Research and
Engineering Laboratory, USDA Agricultural Research Service, Canadian
Foundation for Climate and Atmospheric Sciences, and the Natural
Sciences and Engineering Research Council of Canada is greatly
appreciated. The authors thank three anonymous reviewers and the guest
editor for comments that improved this manuscript.
NR 32
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U1 0
U2 10
PU AMER METEOROLOGICAL SOC
PI BOSTON
PA 45 BEACON ST, BOSTON, MA 02108-3693 USA
SN 1525-755X
J9 J HYDROMETEOROL
JI J. Hydrometeorol.
PD DEC
PY 2008
VL 9
IS 6
BP 1482
EP 1490
DI 10.1175/2008JHM867.1
PG 9
WC Meteorology & Atmospheric Sciences
SC Meteorology & Atmospheric Sciences
GA 386DD
UT WOS:000261861600023
ER
PT J
AU Krishnan, S
Juang, YT
Chowdhury, B
Magilavy, A
Fisher, CU
Nguyen, H
Nambiar, MP
Kyttaris, V
Weinstein, A
Bahjat, R
Pine, P
Rus, V
Tsokos, GC
AF Krishnan, Sandeep
Juang, Yuang-Taung
Chowdhury, Bhabadeb
Magilavy, Abigail
Fisher, Carolyn U.
Nguyen, Hang
Nambiar, Madhusoodana P.
Kyttaris, Vasileios
Weinstein, Arthur
Bahjat, Rena
Pine, Polly
Rus, Violeta
Tsokos, George C.
TI Differential Expression and Molecular Associations of Syk in Systemic
Lupus Erythematosus T Cells
SO JOURNAL OF IMMUNOLOGY
LA English
DT Article
ID RECEPTOR ZETA-CHAIN; PROTEIN-TYROSINE KINASES; SIGNAL-TRANSDUCTION;
ACTIVATION; DEFECTS; COMPLEX; VAV; AUTOIMMUNITY; INHIBITOR; DISEASE
AB Diminished expression of TCR zeta and reciprocal up-regulation and association of FcR gamma with the TCR/CD3 complex is a hallmark of systemic lupus erythematosus (SLE) T cells. In this study we explored whether differential molecular associations of the spleen tyrosine kinase Syk that preferentially binds to FcR gamma contribute to pathological amplification of signals downstream of this "rewired TCR" in SLE. We detected higher amounts of Syk expression and activity in SLE compared with normal T cells. Selective inhibition of the activity of Syk reduced the strength of T CR-induced calcium responses and slowed the rapid kinetics of actin polymerization exclusively in SLE T cells. Syk and ZAP-70 also associated differently with key molecules involved in cytoskeletal and calcium signaling in SLE T cells. Thus, while Vav-1 and LAT preferentially bound to Syk, phospholipase C-gamma 1 bound to both Syk and ZAP-70. Our results show that differential associations of Syk family kinases contribute to the enhanced TCR-induced signaling responses in SLE T cells. Thus, we propose molecular targeting of Syk as a measure to control abnormal T cell responses in SLE. The Journal of Immunology, 2008, 181: 8145-8152.
C1 [Tsokos, George C.] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Med,Div Rheumatol, Boston, MA 02115 USA.
[Krishnan, Sandeep; Chowdhury, Bhabadeb; Fisher, Carolyn U.; Nambiar, Madhusoodana P.] Walter Reed Army Inst Res, Dept Cellular Injury, Silver Spring, MD 20910 USA.
[Nguyen, Hang] Walter Reed Army Med Ctr, Rheumatol Serv, Washington, DC 20307 USA.
[Weinstein, Arthur] Washington Hosp Ctr, Rheumatol Sect, Washington, DC 20010 USA.
[Bahjat, Rena; Pine, Polly] Rigel Pharmaceut, San Francisco, CA 94080 USA.
[Rus, Violeta] Univ Maryland, Sch Med, Dept Med, Baltimore, MD 21201 USA.
RP Tsokos, GC (reprint author), Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Med,Div Rheumatol, Boston, MA 02115 USA.
EM gtsokos@bidmic.harvard.edu
FU National Institutes of Health [R01 A142269]
FX This work Was Supported by National Institutes of Health Grants R01
A142269. The opinions expressed herin are the private ones of the
authors and they do not represent those of the Department of Defense or
the Department of the Army.
NR 24
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U2 0
PU AMER ASSOC IMMUNOLOGISTS
PI BETHESDA
PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 USA
SN 0022-1767
J9 J IMMUNOL
JI J. Immunol.
PD DEC 1
PY 2008
VL 181
IS 11
BP 8145
EP 8152
PG 8
WC Immunology
SC Immunology
GA 376YX
UT WOS:000261220000080
PM 19018007
ER
PT J
AU Ned, RM
Price, AE
Crawford, SB
Ayisi, JG
van Eijk, AM
Otieno, JA
Nahlen, BL
Steketee, RW
Slutsker, L
Shi, YP
Lanar, DE
Udhayakumar, V
AF Ned, Renee M.
Price, April E.
Crawford, Sara B.
Ayisi, John G.
van Eijk, Anna Maria
Otieno, Juliana A.
Nahlen, Bernard L.
Steketee, Richard W.
Slutsker, Laurence
Shi, Ya Ping
Lanar, David E.
Udhayakumar, Venkatachalam
TI Effect of Placental Malaria and HIV Infection on the Antibody Responses
to Plasmodium falciparum in Infants
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article
ID MEROZOITE SURFACE PROTEIN-1; IMMUNODEFICIENCY-VIRUS-INFECTION;
ASYMPTOMATIC PREGNANT-WOMEN; LIVER-STAGE ANTIGEN-1; WESTERN KENYA;
MATERNAL HIV; IMMUNE-RESPONSES; RISK-FACTORS; HUMORAL IMMUNITY;
TRANSMISSION
AB Background. Placental malaria (PM) and maternal infection with human immunodeficiency virus (HIV) type 1 have been shown to affect infant morbidity and immune responses to Plasmodium falciparum. We studied the effects of PM and HIV infection on the antimalarial antibody responses and morbidity outcomes of infants throughout the first year of life.
Methods. A total of 411 Kenyan infants who were born to mothers who were singly or dually infected with PM and/or HIV had their levels of immunoglobulin G antibody to 6 P. falciparum antigens/epitopes (apical membrane antigen-1, erythrocyte-binding antigen-175; liver-stage antigen-1 [LSA-1], circumsporozoite protein [CSP], merozoite surface protein-2, and rhoptry-associated protein-1 [RAP-1]) and to tetanus toxoid (TT) tested using enzyme-linked immunosorbent assay.
Results. PM had little effect on the antibody responses of infants, whereas maternal HIV infection resulted in decreased levels of antibody to LSA-1, CSP, and RAP-1 epitopes at birth, compared with the absence of PM and maternal HIV infection (P < .0063). Levels of antibodies to TT were significantly reduced in infants born to mothers coinfected with HIV and PM, compared with the levels noted in infants born to HIV-negative mothers (P < .0003). In HIV-infected infants, levels of antibody to TT were reduced, but levels of antibody to malarial antigens were not. Antimalarial antibody levels were positively associated with malaria-related morbidity outcomes.
Conclusion. Infant HIV infection and maternal coinfection with HIV and PM negatively influence antibody responses to TT, but not those to malarial antigens, in infants. Antimalarial antibodies rarely showed protective associations with morbidity in infants and were more often a marker for malaria exposure and risk of infection.
C1 [Ned, Renee M.; Price, April E.; Steketee, Richard W.; Slutsker, Laurence; Shi, Ya Ping; Udhayakumar, Venkatachalam] Ctr Dis Control & Prevent, Malaria Branch, Chamblee, GA 30341 USA.
[Crawford, Sara B.] Ctr Dis Control & Prevent, Div Parasit Dis, Natl Ctr Zoonot Vector Borne & Enter Dis, Coordinating Ctr Infect Dis, Chamblee, GA 30341 USA.
[Crawford, Sara B.] Atlanta Res & Educ Fdn, Decatur, GA USA.
[Lanar, David E.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Ayisi, John G.; van Eijk, Anna Maria] Kenya Govt Med Res Ctr, Kisumu, Kenya.
[Otieno, Juliana A.] New Nyanza Prov Hosp, Kisumu, Kenya.
[Nahlen, Bernard L.] WHO, CH-1211 Geneva, Switzerland.
RP Udhayakumar, V (reprint author), Ctr Dis Control & Prevent, Malaria Branch, 4770 Buford Highway,Mail Stop F-12, Chamblee, GA 30341 USA.
EM vxu0@cdc.gov
RI Ned, Renee/D-3746-2009; Lanar, David/B-3560-2011
FU Atlanta Research and Educational Foundation; Centers for Disease Control
and Prevention (CDC)/Division of HIV and AIDS Prevention [CDC IAA
98FED09325]; Emerging Infectious Diseases (EID) Postdoctoral Fellowship
Program
FX Financial support: Atlanta Research and Educational Foundation and
Centers for Disease Control and Prevention (CDC)/Division of HIV and
AIDS Prevention (grant CDC IAA 98FED09325). R.M.N. was supported by an
appointment to the Emerging Infectious Diseases (EID) Postdoctoral
Fellowship Program, and A. E. P. was supported by an appointment to the
EID Training Fellowship Program; both programs were administered by the
Association of Public Health Laboratories and funded by the CDC.
NR 41
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U1 0
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PU UNIV CHICAGO PRESS
PI CHICAGO
PA 1427 E 60TH ST, CHICAGO, IL 60637-2954 USA
SN 0022-1899
J9 J INFECT DIS
JI J. Infect. Dis.
PD DEC 1
PY 2008
VL 198
IS 11
BP 1609
EP 1619
DI 10.1086/593066
PG 11
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 374NY
UT WOS:000261052200006
PM 18928377
ER
PT J
AU Shin, SJ
Cesnik, CES
Wilkie, WK
Wilbur, ML
AF Shin, Sang Joon
Cesnik, Carlos E. S.
Wilkie, W. Keats
Wilbur, Matthew L.
TI Design and Manufacturing of a Model-scale Active Twist Rotor Prototype
Blade
SO JOURNAL OF INTELLIGENT MATERIAL SYSTEMS AND STRUCTURES
LA English
DT Article
DE active twist rotor; blade integral actuation; piezoelectric composite
actuator; helicopter vibration control
ID REDUCTION; BEAMS
AB The design and manufacturing of an active twist rotor blade for vibration reduction in helicopters are presented. The rotor blade is integrally twisted by direct strain actuation through embedded piezoelectric fiber composite actuators distributed along the span of the blade. Highlights of the analysis formulation used to design this type of active blade are presented. The requirements for the prototype blade, along with the final design results are also presented. Detailed aspects of its manufacturing are described. Experimental structural characteristics of the prototype blade compare well with design goals, and bench actuation tests characterize its basic actuation performance. The design and manufacturing processes permit the realization of an active blade that satisfies a given set of design requirements. This is used to later develop a fully active rotor blade system.
C1 [Shin, Sang Joon] Seoul Natl Univ, Inst Adv Aerosp Technol, Seoul 151742, South Korea.
[Cesnik, Carlos E. S.] Univ Michigan, Dept Aerosp Engn, Ann Arbor, MI 48109 USA.
[Wilkie, W. Keats] NASA, Jet Prop Lab, Mech Syst Div, Pasadena, CA 91109 USA.
[Wilbur, Matthew L.] USA, Res Lab, NASA, Langley Res Ctr, Hampton, VA 23681 USA.
RP Shin, SJ (reprint author), Seoul Natl Univ, Inst Adv Aerosp Technol, Seoul 151742, South Korea.
EM ssjoon@snu.ac.kr
FU NASA [NCC 1-323]
FX The authors acknowledge the financial support and technical assistance
from Mr. Paul H. Mirick (formerly U. S. Army Vehicle Technology
Directorate, NASA Langley Research Center). The authors are also
thankful to Dr. John P. Rodgers (Starboard Innovation Inc.) for his
support to the blade fabrication, and to Mr. Gary Fleming and Ms. Emily
Pryputniewics (NASA Langley's Advanced Measurement and Diagnostics
Branch) for conducting the PMI tests. This work was sponsored by NASA
Langley Research Center under cooperative agreement NCC 1-323.
NR 38
TC 11
Z9 11
U1 0
U2 4
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 1045-389X
J9 J INTEL MAT SYST STR
JI J. Intell. Mater. Syst. Struct.
PD DEC
PY 2008
VL 19
IS 12
BP 1443
EP 1456
DI 10.1177/1045389X07088051
PG 14
WC Materials Science, Multidisciplinary
SC Materials Science
GA 375JP
UT WOS:000261110300007
ER
PT J
AU Lin, T
Yang, Q
Tan, CH
Liu, B
McDonald, A
AF Lin, Timothy (Zhigang)
Yang, Quan
Tan, Chuhu
Liu, Bob
McDonald, Adolphus
TI Processing and ballistic performance of lightweight armors based on
ultra-fine-grain aluminum composites
SO JOURNAL OF MATERIALS SCIENCE
LA English
DT Article; Proceedings Paper
CT 5th International Symposium on Ultrafine-Grained Materials
CY MAR 09-13, 2008
CL New Orleans, LA
ID BEHAVIOR; STRAIN; RATES
AB Over last few decades, Al-based metal matrix composites (MMCs) have become a promising material of choice for lightweight armors in vehicles. Recent development in ultra-fine-grain and nanostructured material technology provides a new opportunity for the substantial strength enhancement of MMCs unattainable with the conventional microstructure of microscale, leading to significant weight reduction in armor packages. In this article, we will present the latest development of a novel class of nanostructured metal matrix composites (NMMCs) based on submicron SiC particulates reinforced nanocrystalline Al alloys. The successful fabrication of large-dimension NMMCs plates with a cost-effective synthesis and consolidation process that can be scaled up for mass production will be demonstrated. The microstructure, processing, mechanical properties, and their correlations of this class of NMMCs will also be reported. The ballistic performance of the NMMCs is investigated through a real test of high-speed machinegun bullets, and a numerical modeling as well.
C1 [Lin, Timothy (Zhigang); Yang, Quan; Tan, Chuhu; Liu, Bob] Aegis Technol Inc, Santa Ana, CA 92703 USA.
[McDonald, Adolphus] USA, Aviat & Missile Command, Huntsville, AL 35898 USA.
RP Lin, T (reprint author), Aegis Technol Inc, 3300-A Westminster Ave, Santa Ana, CA 92703 USA.
EM timlin@aegistech.net
NR 9
TC 10
Z9 10
U1 1
U2 13
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0022-2461
J9 J MATER SCI
JI J. Mater. Sci.
PD DEC
PY 2008
VL 43
IS 23-24
BP 7344
EP 7348
DI 10.1007/s10853-008-2977-3
PG 5
WC Materials Science, Multidisciplinary
SC Materials Science
GA 387LD
UT WOS:000261952800015
ER
PT J
AU Pan, Z
Guo, YZ
Mathaudhu, SN
Kecskes, LJ
Hartwig, KT
Wei, Q
AF Pan, Z.
Guo, Y. Z.
Mathaudhu, S. N.
Kecskes, L. J.
Hartwig, K. T.
Wei, Q.
TI Quasi-static and dynamic mechanical properties of commercial-purity
tungsten processed by ECAE at low temperatures
SO JOURNAL OF MATERIALS SCIENCE
LA English
DT Article; Proceedings Paper
CT 5th International Symposium on Ultrafine-Grained Materials
CY MAR 09-13, 2008
CL New Orleans, LA
ID STRAIN-RATE; POLYCRYSTALLINE TUNGSTEN; ULTRAFINE GRAIN; NANOCRYSTALLINE;
COMPRESSION; FAILURE; METALS
AB In this work, we have processed commercial purity tungsten (W) via different routes of equal-channel angular extrusion (ECAE) at temperatures as low as 600 A degrees C. We have systematically evaluated the quasi-static and dynamic compressive behaviors of the processed W. Quasi-static compression tests were performed using an MTS hydro-servo system at room temperature. It is observed that samples ECAE processed at 800 A degrees C show higher yield and flow stresses than those processed at other temperatures; no obvious strain hardening is observed in the quasi-static stress-strain curves. Quasi-static strain rate jump tests show that the strain rate sensitivity of ECAE W is in the range of 0.02 to 0.03, smaller than that of coarse-grained W. Uni-axial dynamic compressive tests were performed using the Kolsky bar (or split-Hopkinson pressure bar, SHPB) system. Post-loading SEM observations revealed that under dynamic compression, the competition between cracking at pre-existing extrinsic surface defects, grain boundaries, and uniform plastic deformation of the individual grains control the overall plastic deformation of the ECAE W. The existence of flow softening under dynamic loading has been established for all of the ECAE W specimens.
C1 [Pan, Z.; Guo, Y. Z.; Wei, Q.] Univ N Carolina, Dept Mech Engn & Engn Sci, Charlotte, NC 28223 USA.
[Mathaudhu, S. N.; Kecskes, L. J.] USA, Res Lab, Weap & Mat Res Directorate, AMSRD ARL WM MB, Aberdeen Proving Ground, MD 21005 USA.
[Hartwig, K. T.] Texas A&M Univ, Dept Mech Engn, College Stn, TX 77843 USA.
RP Wei, Q (reprint author), Univ N Carolina, Dept Mech Engn & Engn Sci, 9201 Univ City Blvd, Charlotte, NC 28223 USA.
EM qwei@uncc.edu
RI Wei, Qiuming/B-7579-2008; Pan, Zhiliang/A-8061-2009; Mathaudhu,
Suveen/B-4192-2009; Kecskes, Laszlo/F-6880-2014; Guo, Yazhou/E-3318-2016
OI Pan, Zhiliang/0000-0003-3899-8761; Kecskes, Laszlo/0000-0002-1342-3729;
NR 19
TC 6
Z9 6
U1 1
U2 17
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0022-2461
J9 J MATER SCI
JI J. Mater. Sci.
PD DEC
PY 2008
VL 43
IS 23-24
BP 7379
EP 7384
DI 10.1007/s10853-008-2788-6
PG 6
WC Materials Science, Multidisciplinary
SC Materials Science
GA 387LD
UT WOS:000261952800021
ER
PT J
AU Lin, T
Tan, CH
Liu, B
McDonald, A
AF Lin, Timothy (Zhigang)
Tan, Chunhu
Liu, Bob
McDonald, Adolphus
TI Microstructure of AA2024-SiC nanostructured metal matrix composites
SO JOURNAL OF MATERIALS SCIENCE
LA English
DT Article; Proceedings Paper
CT 5th International Symposium on Ultrafine-Grained Materials
CY MAR 09-13, 2008
CL New Orleans, LA
ID MECHANICAL-BEHAVIOR; ALLOYS
AB Nanostructured metal matrix composites (NMMCs) in large-dimension billets were fabricated by hot isostatic pressing (HIPing) of cryomilled powders consisting of AA2024 alloy reinforced by 25 wt.% SiC particles. Microstructure of the bulk nanostructured composites and cryomilled powders was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). In addition, mechanical properties of the bulk nanocomposites were also addressed.
C1 [Lin, Timothy (Zhigang); Tan, Chunhu; Liu, Bob] Aegis Technol Inc, Santa Ana, CA 92703 USA.
[McDonald, Adolphus] USA, Aviat & Missile Command, Redstone Arsenal, AL 35898 USA.
RP Lin, T (reprint author), Aegis Technol Inc, 3300 A Westminster Ave, Santa Ana, CA 92703 USA.
EM timlin@aegistech.net
NR 9
TC 2
Z9 2
U1 1
U2 4
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0022-2461
J9 J MATER SCI
JI J. Mater. Sci.
PD DEC
PY 2008
VL 43
IS 23-24
BP 7507
EP 7512
DI 10.1007/s10853-008-2726-7
PG 6
WC Materials Science, Multidisciplinary
SC Materials Science
GA 387LD
UT WOS:000261952800040
ER
PT J
AU Wallace, SM
Szabo, KA
Schlabritz-Loutsevitch, NE
Dick, EJ
Blanchard, TW
Hubbard, GB
AF Wallace, Shannon M.
Szabo, Kathleen A.
Schlabritz-Loutsevitch, Natalia E.
Dick, Edward J.
Blanchard, Terrell W.
Hubbard, Gene B.
TI Myxomatous neoplasms in the perineal region of baboons
SO JOURNAL OF MEDICAL PRIMATOLOGY
LA English
DT Article
DE Aggressive angiomyxoma; angiomyofibroblastoma; cdk4; estrogen receptor;
MDM2; progesterone receptor
ID FEMALE GENITAL-TRACT; AGGRESSIVE ANGIOMYXOMA; ANGIOMYOFIBROBLASTOMA;
EXPRESSION; VULVA; COW
AB Background In baboons, Papio sp. neoplasms tend to affect the hematopoietic system most commonly, with rare documentation of myxomatous neoplasms. In contrast, women can develop myxomatous masses within deep peripelvic tissues with some frequency during their reproductive years.
Methods We have identified and examined, retrospectively, myxomatous perineal masses in twelve female baboons within one research facility and compared their histopathologic, immunohistochemical and electron microscopic features to their human variants.
Results Our results indicate that these myxomatous neoplasms, in humans and non-human primates, share common features.
Conclusion Further research, particularly molecular genetic analysis, may be needed to identify the baboon as a true animal model for myxomatous perineal neoplasms.
C1 [Wallace, Shannon M.; Szabo, Kathleen A.] Walter Reed Army Inst Res, Dept Pathol, Silver Spring, MD 20910 USA.
[Schlabritz-Loutsevitch, Natalia E.] Univ Texas Hlth Sci Ctr San Antonio, San Antonio, TX 78229 USA.
[Blanchard, Terrell W.] Armed Forces Inst Pathol, Washington, DC 20306 USA.
[Dick, Edward J.; Hubbard, Gene B.] SW Fdn Biomed Res, SW Natl Primate Res Ctr, San Antonio, TX 78284 USA.
RP Wallace, SM (reprint author), Walter Reed Army Inst Res, Dept Pathol, 503 Robert Grant Ave, Silver Spring, MD 20910 USA.
EM shannon.m.wallace@us.army.mil
FU NCRR NIH HHS [P51 RR013986]
NR 33
TC 2
Z9 2
U1 0
U2 0
PU WILEY-BLACKWELL
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 0047-2565
J9 J MED PRIMATOL
JI J. Med. Primatol.
PD DEC
PY 2008
VL 37
IS 6
BP 261
EP 270
DI 10.1111/j.1600-0684.2008.00293.x
PG 10
WC Veterinary Sciences; Zoology
SC Veterinary Sciences; Zoology
GA 367FW
UT WOS:000260538900001
PM 19017193
ER
PT J
AU Thatch, KA
Schwartz, MZ
Yoo, EY
Mendelson, KG
Duke, DS
AF Thatch, Keith A.
Schwartz, Marshall Z.
Yoo, Edward Y.
Mendelson, Kim G.
Duke, Duane S.
TI Modulation of the inflammatory response and apoptosis using epidermal
growth factor and hepatocyte growth factor in a liver injury model: a
potential approach to the management and treatment of cholestatic liver
disease
SO JOURNAL OF PEDIATRIC SURGERY
LA English
DT Article; Proceedings Paper
CT 41st Annual Meeting of the Pacific-Association-of-Pediatric-Surgeons
CY JUN 29-JUL 03, 2008
CL Grand Teton Natl Pk, WY
SP Pacific Assoc Pediat Surg
DE Short bowel syndrome; TPN; Liver injury; Liver disease;
alpha-Naphtylisocyocyanate; Hepatocyte growth factor; Epithelial growth
factor
ID TOTAL PARENTERAL-NUTRITION; SHORT-BOWEL SYNDROME; INTESTINAL ADAPTATION;
REGENERATION; PREVENTION; GLUCAGON; CHILDREN; RECEPTOR; FAILURE; RATS
AB Background/Purpose: The major side effect of total parenteral nutrition is liver injury leading to liver failure. This Study was designed to assess specific growth factors in modulating the hepatic response in an ANIT-induced liver-injury model.
Methods: Sprague-Dawley rats were divided into four groups: control (n = 5), liver-injury control (alpha-naphtylisocyocyanate [ANIT], 100 mg/kg, n = 8), ANIT + epidermal growth factor(EGF, 150 mu g/kg per (Jay, n = 10), and ANIT + hepatocyte growth factor (HGF, 250 mu g/kg per clay, n = 9). Rats were given intraperitoneal injections of saline (control) or ANIT and implantation of an osmotic mini-pump for 7 days of continuous intravenous Saline (liver injury control), EGF, or FIGF. Seven and 14 days later, liver biopsies were obtained and evaluated for interleukin (IL)-6 and tumor necrosis factor a expression by immunofluorescent staining, and for apoptosis, by the terminal transferase dUTP nick end labeling (TUNEL) technique. All animals were euthanized at 14 clays.
Results: Epidermal growth factor (P < .025) and HGF (P < .001) groups induced less IL-6 expression at day 14 compared to liver-injury controls. In addition, the interval decrease in IL-6 expression between days 7 and 14 was greater in EGF (P < .001) and HGF (P <.001) groups compared to liver-injury controls. At clay 14, FIGF also demonstrated decreased tumor necrosis factor cl expression (P <.005). Apoptotic activity was significantly less for the EGF (P < .011) and HGF (P < .0012) groups.
Conclusion: Epidermal growth factor and HGF modulated the hepatic inflammatory response and apoptotic index in this established liver-injury model and may diminish or prevent liver damage in patients with total parenteral nutrition-induced liver injury. (C) 2009 Published by Elsevier Inc.
C1 [Thatch, Keith A.; Schwartz, Marshall Z.; Yoo, Edward Y.; Mendelson, Kim G.] St Christophers Hosp Children, Philadelphia, PA 19134 USA.
[Thatch, Keith A.; Schwartz, Marshall Z.; Yoo, Edward Y.; Mendelson, Kim G.] Drexel Univ, Coll Med, Philadelphia, PA 19102 USA.
[Duke, Duane S.] Walter Reed Army Med Ctr, Washington, DC 20307 USA.
RP Schwartz, MZ (reprint author), St Christophers Hosp Children, Philadelphia, PA 19134 USA.
EM mzschwartz@msn.com
NR 25
TC 11
Z9 12
U1 0
U2 2
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0022-3468
J9 J PEDIATR SURG
JI J. Pediatr. Surg.
PD DEC
PY 2008
VL 43
IS 12
BP 2169
EP 2173
DI 10.1016/j.jpedsurg.2008.08.045
PG 5
WC Pediatrics; Surgery
SC Pediatrics; Surgery
GA 386AC
UT WOS:000261853700007
PM 19040928
ER
PT J
AU Resio, DT
Perrie, W
AF Resio, Donald T.
Perrie, William
TI A Two-Scale Approximation for Efficient Representation of Nonlinear
Energy Transfers in a Wind Wave Spectrum. Part I: Theoretical
Development
SO JOURNAL OF PHYSICAL OCEANOGRAPHY
LA English
DT Article
ID FINITE DEPTH WATER; EQUILIBRIUM RANGE; GENERATED WAVES; GRAVITY-WAVES;
MODEL; PARAMETERIZATIONS; COMPUTATIONS; SIMILARITY; PREDICTION
AB A new method for estimating the transfer rates in wind wave spectra is derived and tested, based on a two-scale approximation (TSA) to the total integral for quadruplet wave-wave interactions. Comparisons of this new estimation method to the full integral are given for several idealized spectra, including Joint North Sea Wave Project spectra with different peakednesses, a finite depth case, and cases with perturbations added to underlying parametric spectra. In particular, these comparisons show that the TSA is a significant improvement over the discrete interaction approximation (DIA) in deep water and an even greater improvement in shallow water.
C1 [Perrie, William] Fisheries & Oceans Canada, Bedford Inst Oceanog, Dartmouth, NS BZY 4AZ, Canada.
[Resio, Donald T.] ERDC Coastal & Hydraul Lab, Vicksburg, MS USA.
RP Perrie, W (reprint author), Fisheries & Oceans Canada, Bedford Inst Oceanog, Dartmouth, NS BZY 4AZ, Canada.
EM perriew@dfo-mpo.gc.ca
FU U.S. Army Corps of Engineers MORPHOS; Canadian Panel on Energy Research
and Development; ONR (U. S. Office of Naval Research) through the Gulf
of Maine Ocean Observing System (GoMOOS); Southeast University Research
Association Coastal Ocean Observing and Prediction (SCOOP); Canada
Foundation for Climate and Atmospheric Studies
FX The authors would like to acknowledge the valuable contributions of the
anonymous reviewers to this paper. Their detailed reviews greatly
improved both the content and accuracy of this manuscript. Support for
this research comes from the U.S. Army Corps of Engineers MORPHOS
program, the Canadian Panel on Energy Research and Development
(PERD-Offshore Environmental Factors Program), ONR (U. S. Office of
Naval Research) through the Gulf of Maine Ocean Observing System
(GoMOOS), the Southeast University Research Association Coastal Ocean
Observing and Prediction (SCOOP) program, and the Canada Foundation for
Climate and Atmospheric Studies. The authors also wish to acknowledge
the Office, Chief of Engineers, U. S. Army Corps of Engineers for
permission to publish this paper.
NR 32
TC 14
Z9 14
U1 0
U2 0
PU AMER METEOROLOGICAL SOC
PI BOSTON
PA 45 BEACON ST, BOSTON, MA 02108-3693 USA
SN 0022-3670
J9 J PHYS OCEANOGR
JI J. Phys. Oceanogr.
PD DEC
PY 2008
VL 38
IS 12
BP 2801
EP 2816
DI 10.1175/2008JPO3713.1
PG 16
WC Oceanography
SC Oceanography
GA 386ZJ
UT WOS:000261921200012
ER
PT J
AU Zhang, X
Mi, CC
Masrur, A
Daniszewski, D
AF Zhang, Xi
Mi, Chris Chunting
Masrur, Abul
Daniszewski, David
TI Wavelet-transform-based power management of hybrid vehicles with
multiple on-board energy sources including fuel cell, battery and
ultracapacitor
SO JOURNAL OF POWER SOURCES
LA English
DT Article
DE Hybrid electric vehicle; Wavelet transform; Wavelet decomposition; Power
management; Power demand; Powerflow
ID LITHIUM-ION BATTERY; ELECTRIC VEHICLES; HAAR WAVELET; MODEL; SYSTEM;
SUPERCAPACITOR; SIMULATION
AB A wavelet-transform-based strategy is proposed for the power management of hybrid electric vehicles (HEV) with multiple on-board energy sources and energy storage systems including a battery, a fuel cell, and an ultra-capacitor. The proposed wavelet-transform algorithm is capable of identifying the high-frequency transient and real time power demand of the HEV, and allocating power components with different frequency contents to corresponding sources to achieve an optimal power management control algorithm. By using the wavelet decomposition algorithm, a proper combination can be achieved with a properly sized Ultra-capacitor dealing with the chaotic high-frequency components of the total power demand, while the fuel cell and battery deal with the low and medium frequency power demand. Thus the system efficiency and life expectancy can be greatly extended. Simulation and experimental results validated the effectiveness of wavelet-transform-based power management algorithm. (C) 2008 Elsevier B.V. All rights reserved.
C1 [Zhang, Xi; Mi, Chris Chunting] Univ Michigan, Dept Elect & Comp Engn, Dearborn, MI 48128 USA.
[Masrur, Abul; Daniszewski, David] USA, RDECOM TARDEC, Warren, MI USA.
RP Mi, CC (reprint author), Univ Michigan, Dept Elect & Comp Engn, 4901 Evergreen Rd, Dearborn, MI 48128 USA.
EM chrismi@umich.edu
RI Mi, Chunting/E-3769-2013
OI Mi, Chunting/0000-0002-5471-8953
NR 28
TC 57
Z9 59
U1 5
U2 22
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0378-7753
EI 1873-2755
J9 J POWER SOURCES
JI J. Power Sources
PD DEC 1
PY 2008
VL 185
IS 2
BP 1533
EP 1543
DI 10.1016/j.jpowsour.2008.08.046
PG 11
WC Chemistry, Physical; Electrochemistry; Energy & Fuels; Materials
Science, Multidisciplinary
SC Chemistry; Electrochemistry; Energy & Fuels; Materials Science
GA 384MM
UT WOS:000261748900138
ER
PT J
AU Rupp, TL
Macauslan, J
Boyce, S
Balkin, TJ
AF Rupp, T. L.
Macauslan, J.
Boyce, S.
Balkin, T. J.
TI Speech degradation with sleep restriction and recovery
SO JOURNAL OF SLEEP RESEARCH
LA English
DT Meeting Abstract
CT 19th Congress of the European-Sleep-Research-Society
CY SEP 09-13, 2008
CL Glasgow, SCOTLAND
SP European Sleep Res Soc
C1 [Rupp, T. L.; Balkin, T. J.] Walter Reed Army Inst Res, Silver Spring, MD USA.
[Macauslan, J.; Boyce, S.] STAR Analyt Serv, Bedford, MA USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL PUBLISHING, INC
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 0962-1105
J9 J SLEEP RES
JI J. Sleep Res.
PD DEC
PY 2008
VL 17
BP 226
EP 226
PG 1
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 400EH
UT WOS:000262850300637
ER
PT J
AU Jernajczyk, W
Ignaccolo, M
Latka, M
West, BJ
AF Jernajczyk, W.
Ignaccolo, M.
Latka, M.
West, B. J.
TI Diffusion entropy analysis of sleep EEG
SO JOURNAL OF SLEEP RESEARCH
LA English
DT Meeting Abstract
CT 19th Congress of the European-Sleep-Research-Society
CY SEP 09-13, 2008
CL Glasgow, SCOTLAND
SP European Sleep Res Soc
C1 [Jernajczyk, W.] Inst Psychiat & Neurol, Dept Clin Neurophysiol, Warsaw, Poland.
[Ignaccolo, M.] Duke Univ, Durham, NC USA.
[Latka, M.] Wroclaw Univ Technol, PL-50370 Wroclaw, Poland.
[West, B. J.] USA, Res Off, Math & Informat Sci Directorate, Res Triangle Pk, NC 27709 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU WILEY-BLACKWELL PUBLISHING, INC
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 0962-1105
J9 J SLEEP RES
JI J. Sleep Res.
PD DEC
PY 2008
VL 17
BP 229
EP 229
PG 1
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA 400EH
UT WOS:000262850300647
ER
PT J
AU Yasuda, T
Brechue, WF
Fujita, T
Sato, Y
Abe, T
AF Yasuda, Tomohiro
Brechue, William F.
Fujita, Taku
Sato, Yoshiaki
Abe, Takashi
TI Muscle activation during low-intensity muscle contractions with varying
levels of external limb compression
SO JOURNAL OF SPORTS SCIENCE AND MEDICINE
LA English
DT Article
DE Neuromuscular function; EMG; cuff pressure; biceps brachii; ischemia
ID MODERATE VASCULAR OCCLUSION; RESISTANCE EXERCISE; BLOOD-FLOW; MUSCULAR
FUNCTION; FATIGUE; RESTRICTION; RESPONSES; STRENGTH; HORMONE; HUMANS
AB The purpose was to investigate muscle activation during low-intensity muscle contractions with various levels of external limb compression to reduce muscle perfusion/outflow. A series of unilateral elbow flexion muscle contractions (30 repetitive contractions followed by 3 sets x 15 contractions) was performed at 20% of 1RM with varying levels of external compression (0 (without compression), 98, 121, and 147 mmHg external compression) around the upper arm. Electromyography (EMG) signals were recorded from surface electrodes placed on the biceps brachii muscle and analyzed for integrated EMG (iEMG). Maximal voluntary isometric contraction (MVC) decreased similarly during the control (0 mmHg) and 98 mmHg external compression bout (similar to 18%); the decline in MVC with 121 and 147 mmHg external compression was significantly greater (similar to 37%). Muscle activation increased progressively throughout the contraction bout with each level of external compression, but iEMG was significantly greater during 147 mmHg external compression. In conclusion, low-intensity muscle contractions performed with external compression of 147 mmHg appears to alter muscle perfusion/outflow leading to increased muscle activation without decrements in work performed during the contraction bout.
C1 [Yasuda, Tomohiro] Univ Tokyo, Grad Sch Med, Dept Ischem Circulatory Physiol, Bunkyo Ku, Tokyo 1138655, Japan.
[Yasuda, Tomohiro; Fujita, Taku] Tokyo Metropolitan Univ, Grad Sch Sci, Dept Exercise & Sport Sci, Tokyo 158, Japan.
[Brechue, William F.] US Mil Acad, Dept Phys Educ, Ctr Phys Dev Excellence, West Point, NY 10996 USA.
[Abe, Takashi] Univ Tokyo, Grad Sch Frontier Sci, Inst Environm Studies, Chiba, Japan.
RP Yasuda, T (reprint author), Univ Tokyo, Grad Sch Med, Dept Ischem Circulatory Physiol, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138655, Japan.
EM yasuda-tomohiro@umin.ac.jp; bill.brechue@usma.edu;
fujitaku_high_low@hotmail.co.jp; info@satosports.co.jp;
abe@k.u-tokyo.ac.jp
FU Japan Ministry of Education, Culture, Sports, Science, and Technology
[15300221 from the]
FX The authors thank the students who participated in this study. We also
thank Dr. Toshiaki Nakajima, Dr. Satoshi Fujita, and Miwa Kurano (The
University of Tokyo) for helpful discussion. This study was supported by
Grant-in-aid 15300221 from the Japan Ministry of Education, Culture,
Sports, Science, and Technology.
NR 27
TC 21
Z9 21
U1 2
U2 10
PU JOURNAL SPORTS SCIENCE & MEDICINE
PI BURSA
PA MEDICAL FACULTY ULUDAG UNIV, DEPT SPORTS MEDICINE, BURSA, 16059, TURKEY
SN 1303-2968
J9 J SPORT SCI MED
JI J. Sport. Sci. Med.
PD DEC
PY 2008
VL 7
IS 4
BP 467
EP 474
PG 8
WC Sport Sciences
SC Sport Sciences
GA 403IX
UT WOS:000263077400007
PM 24149952
ER
PT J
AU Ostashev, VE
Scanlon, MV
Wilson, DK
Vecherin, SN
AF Ostashev, Vladimir E.
Scanlon, Michael V.
Wilson, D. Keith
Vecherin, Sergey N.
TI Source localization from an elevated acoustic sensor array in a
refractive atmosphere
SO JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
LA English
DT Article
AB Localization of sound sources on the ground from an acoustic sensor array elevated on a tethered aerostat is considered. To improve estimation of the source coordinates, one should take into account refraction of sound rays due to atmospheric stratification. Using a geometrical acoustics approximation for a stratified moving medium, formulas for the source coordinates are derived that account for sound refraction. The source coordinates are expressed in terms of the direction of sound propagation as measured by the sensor array, its coordinates, and the vertical profiles of temperature and wind velocity. Employing these formulas and typical temperature and wind velocity profiles in the atmosphere, it is shown numerically that sound refraction is important for accurate predictions of the source coordinates. Furthermore, it is shown that the effective sound speed approximation, which is widely used in atmospheric acoustics, fails to correctly predict the source coordinates if the grazing angle of sound propagation is relatively large. (C) 2008 Acoustical Society of America. [DOI: 10.1121/1.3003085]
C1 [Ostashev, Vladimir E.] NOAA, Earth Syst Res Lab, Boulder, CO 80303 USA.
[Scanlon, Michael V.] USA, Res Lab, AMSRD ARL SE SP, Adelphi, MD 20783 USA.
[Wilson, D. Keith] USA, Engineer Res & Dev Ctr, Hanover, NH 03755 USA.
[Vecherin, Sergey N.] New Mexico State Univ, Dept Phys, Las Cruces, NM 88003 USA.
RP Ostashev, VE (reprint author), NOAA, Earth Syst Res Lab, Boulder, CO 80303 USA.
RI Wilson, D. Keith/A-4687-2012
OI Wilson, D. Keith/0000-0002-8020-6871
FU Army Research Laboratory [W911NF-06-2-0015]
FX This research was supported by the Army Research Laboratory via a
subagreement with the DoD Center for Geosciences/Atmospheric Research at
Colorado State University under Cooperative Agreement W911NF-06-2-0015.
NR 10
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U1 0
U2 2
PU ACOUSTICAL SOC AMER AMER INST PHYSICS
PI MELVILLE
PA STE 1 NO 1, 2 HUNTINGTON QUADRANGLE, MELVILLE, NY 11747-4502 USA
SN 0001-4966
J9 J ACOUST SOC AM
JI J. Acoust. Soc. Am.
PD DEC
PY 2008
VL 124
IS 6
BP 3413
EP 3420
DI 10.1121/1.3003085
PG 8
WC Acoustics; Audiology & Speech-Language Pathology
SC Acoustics; Audiology & Speech-Language Pathology
GA 398XS
UT WOS:000262765600008
PM 19206770
ER
PT J
AU Vertrees, A
Greer, L
Pickett, C
Nelson, J
Wakefield, M
Stojadinovic, A
Shriver, C
AF Vertrees, Amy
Greer, Lauren
Pickett, Chris
Nelson, Jeffery
Wakefield, Matthew
Stojadinovic, Alexander
Shriver, Craig
TI Modern Management of Complex Open Abdominal Wounds of War: A 5-Year
Experience
SO JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
LA English
DT Article; Proceedings Paper
CT 93rd Annual Clinical Congress of the American-College-of-Surgeons
CY OCT 07-11, 2007
CL New Orleans, LA
SP Amer Coll Surg
ID ACELLULAR DERMAL MATRIX; DAMAGE CONTROL; OPEN ABDOMEN; VENTRAL HERNIA;
CLOSURE; MILITARY; IRAQ
AB BACKGROUND: Optimal management of the open abdomen remains controversial.
STUDY DESIGN: Retrospective review of patients injured during Operations Enduring Freedom and Iraqi Freedom returning to Walter Reed Army Medical Center (WRAMC) from January 2003 to October 2007 for treatment of open abdomen.
RESULTS: Three hundred fifty-four patients were evacuated to WRAMC after laparotomy, including 86 patients (24%) with open abdomen. Three transferred patients were excluded. Eighty-three patients, mean age 26 years (range 18 to 54 years), sustaining injury from secondary blast (n = 47), gunshot (n = 29), and blunt trauma (n = 7) were studied. Surgical management included early definitive abdominal closure (EDAC, n = 56; 67%), primary fascial closure (n = 15; 18%), planned ventral hernia (PVH, n = 9; 11 %) and vacuum-assisted closure with AlloDerm (n = 3; 4%). EDAC closure involves serial closure with Gore-Tex Dualmesh and final closure supplemented with polypropylene mesh (62%) or AlloDerm (31%). There was no substantial difference in injury mechanism, age, length of evacuation to WRAMC, or Injury Severity Score (average 30) according to closure type. Complications included removal of infected prosthetic mesh in 4 EDAC closure patients (5%). Overall morbidity was lowest (60%) in primary repair patients (p = 0.01). Rates of deep venous thrombosis, pulmonary embolism, abdominal wall hematoma, and infection did not differ between groups. Fistula rate was increased with PVH (20%). Two patients with PVH died. PVH and EDAC mesh complications have been minimized in the last 2 years of the study.
CONCLUSIONS: Primary closure of fascia is ideal but not always possible. Early definitive closure has avoided PVH. Mesh-related complications have decreased with time. (J Am Coll Surg 2008;207:801-809. (C) 2008 by the American College of Surgeons)
C1 [Vertrees, Amy; Greer, Lauren; Pickett, Chris; Nelson, Jeffery; Wakefield, Matthew; Stojadinovic, Alexander; Shriver, Craig] Walter Reed Army Med Ctr, Washington, DC 20307 USA.
RP Vertrees, A (reprint author), Walter Reed Army Med Ctr, Bldg 2,5th Floor,6900 Georgia Ave NW, Washington, DC 20307 USA.
EM amy.vertrees@amedd.army.mil
NR 16
TC 40
Z9 42
U1 0
U2 5
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1072-7515
J9 J AM COLL SURGEONS
JI J. Am. Coll. Surg.
PD DEC
PY 2008
VL 207
IS 6
BP 801
EP 809
DI 10.1016/j.jamcollsurg.2008.08.014
PG 9
WC Surgery
SC Surgery
GA 382GE
UT WOS:000261592800002
PM 19183525
ER
PT J
AU Turell, MJ
Dohm, DJ
Mores, CN
Terracina, L
Wallette, DL
Hribar, LJ
Pecor, JE
Blow, JA
AF Turell, Michael J.
Dohm, David J.
Mores, Christopher N.
Terracina, Lucas
Wallette, Dennis L., Jr.
Hribar, Lawrence J.
Pecor, James E.
Blow, Jamie A.
TI POTENTIAL FOR NORTH AMERICAN MOSQUITOES TO TRANSMIT RIFT VALLEY FEVER
VIRUS
SO JOURNAL OF THE AMERICAN MOSQUITO CONTROL ASSOCIATION
LA English
DT Article
DE Rift Valley fever; vector; transmission; North America
ID VECTOR COMPETENCE; CULEX-PIPIENS; SAUDI-ARABIA; PHLEBOTOMUS-DUBOSCQI;
SOUTH-AFRICA; SAND FLY; EPIDEMIC; DIPTERA; EGYPT; DISSEMINATION
AB The rapid spread of West Nile viral activity across North America since its discovery in 1999 illustrates the potential for an exotic arbovirus to be introduced and widely established across North America. Rift Valley fever virus (RVFV) has been responsible for large outbreaks in Africa that have resulted in hundreds of thousands of human infections and major economic disrubpiton due to loss of livestock and to trade restrictions. However, little is known about the potential for North American mosquitoes to transmit this virus should it be introduced into North America. Therefore, we evaluated selected mosquito species from the southeastern United States for their ability to serve as potential vectors for RVFV. Mosquitoes were fed on adult hamsters inoculated 1 day previously with RVFV. These mosquitoes were tested for infection and ability to transmit RVFV after incubation at 26 degrees C for 7-21 days. None of the species tested (Aedes taeniorhynchus. Ae. vexans. Culex erraticus. Cx. nigripalpus, Cx. quinquefasciatus, and Cx. Salinarius) were efficient vectors after they fed on hamsters with viremias ranging from 10(4.1) to 10(6.9) plaque-forming units (PFU)/ml. However, Ae, taeniorhynchus, Ae, vexans, and Cx, erraticus all developed disseminated infections after they fed on hamsters with viremias between 10(8.5) and 10(10.2) PFU/ml, and both Ae, vexans and Cx, erraticus transmitted RVFV by bite. These studies illustrate the need to identify the ability of individual mosquito species to transmit RVFV so that appropriate decisions can be made concerning the application of control measures during an outbreak.
C1 [Turell, Michael J.; Dohm, David J.; Mores, Christopher N.; Blow, Jamie A.] USA, Med Res Inst Infect Dis, Div Virol, Ft Detrick, MD 21702 USA.
[Terracina, Lucas] Calcasieu Parish Police Jury, Dept Mosquito & Rodent Control, Lake Charles, LA 70615 USA.
[Wallette, Dennis L., Jr.] Tangipahoa Mosquito Abatement Dist, Hammond, LA 70403 USA.
[Hribar, Lawrence J.] Florida Keys Mosquito Control Dist, Marathon, FL 33050 USA.
[Pecor, James E.] Walter Reed Army Inst Res, Div Entomol, Silver Spring, MD 20907 USA.
RP Turell, MJ (reprint author), USA, Med Res Inst Infect Dis, Div Virol, 1425 Porter St, Ft Detrick, MD 21702 USA.
FU National Biodefense Analysis and Countermeasures Center [04-0-DI-1009]
FX This work was supported by a g-rant (04-0-DI-1009) from the National
Biodefense Analysis and Countermeasures Center.
NR 35
TC 62
Z9 65
U1 0
U2 8
PU AMER MOSQUITO CONTROL ASSOC
PI EATONTOWN
PA P O BOX 234, EATONTOWN, NJ 07724-0234 USA
SN 8756-971X
J9 J AM MOSQUITO CONTR
JI J. Am. Mosq. Control Assoc.
PD DEC
PY 2008
VL 24
IS 4
BP 502
EP 507
DI 10.2987/08-5791.1
PG 6
WC Entomology
SC Entomology
GA 388GJ
UT WOS:000262008000005
PM 19181056
ER
PT J
AU Klun, JA
Kramer, M
Zhang, AJ
Wang, SF
Debboun, M
AF Klun, Jerome A.
Kramer, Matthew
Zhang, Aijun
Wang, Shifa
Debboun, Mustapha
TI A QUANTITATIVE IN VITRO ASSAY FOR CHEMICAL MOSQUITO-DETERRENT ACTIVITY
WITHOUT HUMAN BLOOD CELLS
SO JOURNAL OF THE AMERICAN MOSQUITO CONTROL ASSOCIATION
LA English
DT Article
DE Aedes aegypti; Anopheles stephensi; N,N-diethyl-3-methylbenzamide; ATP;
mosquito biting; isolongifolenone; CPDA-1
ID AEDES-AEGYPTI; CALLICARPA-AMERICANA; ATP; PHAGOSTIMULANTS; CULICIDAE
AB We report that an aqueous solution containing 10(-3) M adenosine triphosphate (ATP) and citrate-phosphate-dextrose-adenine (CPDA-1) can effectively replace transfusable human red blood cells in an in vitro Klun and DEbboun bioassay system for evaluating chemicals for mosquito feeding-deterrent activity, using either Aedes aegypti or Anopoheles stephensi. These species fed with similar avidity through collagen membrane covering aqueous 10(-3) M ATP plus CPDA-1 or red blood cells in CPDA-1 supplemented with ATP. In a 2nd experiment, we evaluated the feeding-deterrent activity of N,N-diethyl-3-methylbenzamide and a newly discovered natural product chemical, (-)-isolongifolenone, against these 2 mosquito species. We found that the feeding-deterrent efficacy of the 2 chemicals was similar whether the feeding stimulant was red blood cells supplemented with ATP or ATP alone with CPDA-1. Since the use of human red blood cells in bioassays raises important health and logistic issues, aqueous ATP with CPDA-1 is a reasonable alternative to human blood cells for routine in vitoro chemical screening.
C1 [Klun, Jerome A.; Zhang, Aijun] ARS, USDA, Insect Biocontrol & Behav Lab, Beltsville, MD 20705 USA.
[Kramer, Matthew] ARS, USDA, Biometr Consulting Serv, Beltsville, MD 20705 USA.
[Wang, Shifa] Nanjing Forestry Univ, Coll Chem Engn, Nanjing 210037, Jiangsu, Peoples R China.
[Debboun, Mustapha] USA, Med Dept Ctr & Sch, Acad Hlth Sci, Dept Prevent Hlth Serv,Med Zool Branch, Ft Sam Houston, TX 78234 USA.
RP Klun, JA (reprint author), ARS, USDA, Insect Biocontrol & Behav Lab, Beltsville, MD 20705 USA.
NR 18
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Z9 15
U1 1
U2 7
PU AMER MOSQUITO CONTROL ASSOC
PI EATONTOWN
PA P O BOX 234, EATONTOWN, NJ 07724-0234 USA
SN 8756-971X
J9 J AM MOSQUITO CONTR
JI J. Am. Mosq. Control Assoc.
PD DEC
PY 2008
VL 24
IS 4
BP 508
EP 512
DI 10.2987/08-5755.1
PG 5
WC Entomology
SC Entomology
GA 388GJ
UT WOS:000262008000006
PM 19181057
ER
PT J
AU Hughes, TH
Irwin, PM
Kaufman, A
Sage, H
Pagac, BB
Paskewitz, SM
AF Hughes, Tony H.
Irwin, Patrick M.
Kaufman, Andrew
Sage, Heather
Pagac, Benedict B., Jr.
Paskewitz, Susan M.
TI FIRST RECORDS OF AEDES JAPONICUS JAPONICUS IN WISCONSIN
SO JOURNAL OF THE AMERICAN MOSQUITO CONTROL ASSOCIATION
LA English
DT Article
DE Aedes japonicus japonicus; first record; human landing catch; vector
ID LA-CROSSE VIRUS; OCHLEROTATUS-JAPONICUS; CULICIDAE; DIPTERA; MOSQUITOS;
THEOBALD
AB Aedes japonicus japonicus was collected via gravid trapping in Wisconsin in the summers of 2004 and 2005 at Fort McCoy, Monroe County, Subsequently, in summer of 2007, Ae. japonicus was captured in a human landing catch in Dane County, Madison, WI. Additional collections were made at this site in the spring of 2008. Invasion is in progress, but significant population increases have not yet been confirmed.
C1 [Hughes, Tony H.; Irwin, Patrick M.; Kaufman, Andrew; Sage, Heather; Paskewitz, Susan M.] Univ Wisconsin, Dept Entomol, Madison, WI 53706 USA.
[Pagac, Benedict B., Jr.] USA, Entomol Sci Div, Ctr Hlth Promot & Prevent Med N, Ft George G Meade, MD 20755 USA.
RP Paskewitz, SM (reprint author), Univ Wisconsin, Dept Entomol, 237 Russell Labs,1630 Linden Dr, Madison, WI 53706 USA.
NR 14
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Z9 12
U1 3
U2 4
PU AMER MOSQUITO CONTROL ASSOC
PI EATONTOWN
PA P O BOX 234, EATONTOWN, NJ 07724-0234 USA
SN 8756-971X
J9 J AM MOSQUITO CONTR
JI J. Am. Mosq. Control Assoc.
PD DEC
PY 2008
VL 24
IS 4
BP 583
EP 584
DI 10.2987/5735.1
PG 2
WC Entomology
SC Entomology
GA 388GJ
UT WOS:000262008000017
PM 19181068
ER
PT J
AU Weiss, BM
Shumway, NM
Howard, RS
Ketchum, LK
Reid, TJ
AF Weiss, Brendan M.
Shumway, Nathan M.
Howard, Robin S.
Ketchum, Lloyd K.
Reid, Thomas J.
TI Optical density values correlate with the clinical probability of
heparin induced thrombocytopenia
SO JOURNAL OF THROMBOSIS AND THROMBOLYSIS
LA English
DT Article; Proceedings Paper
CT 2nd Annual Meeting of the
International-Society-of-the-Cardiovascular-Translational-Research
CY FEB 27-28, 2009
CL San Diego, CA
SP Int Soc Cardiovasc Translat Res, Catholic Healthcare W
DE Heparin-induced thrombocytopenia; Enzyme linked immunosorbent assay;
Predictive value of tests
ID D-DIMER; DIAGNOSIS; ANTIBODIES; MANAGEMENT; THROMBOSIS; SCORE
AB Introduction Heparin induced thrombocytopenia is a clinicopathologic syndrome that may result in severe thrombotic sequelae without prompt diagnosis and treatment. A clinical scoring system to assess the pre-test probability of heparin-induced thrombocytopenia, the 4 T's, has been reported to correlate with the serotonin release assay. Materials and methods We performed a single-center, retrospective study correlating the 4 T's score with the commercial heparin-PF4 ELISA. Results One hundred forty four cases were identified. The pre-test probability scores were: low probability 45.8%, moderate probability 41.0% and high probability 13.2%. The median optical density was 0.148, 0.223 and 0.470 for low probability, moderate probability and high probability, respectively (P < 0.0005). The frequencies of obtaining an optical density > 1.00 for these probability scores were 1.5%, 6.8%, and 36.8%, respectively (P < 0.0005). Conclusions Heparin-PF4 ELISA optical density values increase with increasing probability of heparin induced thrombocytopenia.
C1 [Weiss, Brendan M.; Shumway, Nathan M.; Howard, Robin S.; Ketchum, Lloyd K.; Reid, Thomas J.] Walter Reed Army Med Ctr, Dept Med, Hematol Oncol Serv, Washington, DC 20307 USA.
RP Weiss, BM (reprint author), Walter Reed Army Med Ctr, Dept Med, Hematol Oncol Serv, 6900 Georgia Ave NW, Washington, DC 20307 USA.
EM brendan.weiss@us.army.mil
NR 12
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U1 0
U2 1
PU SPRINGER
PI DORDRECHT
PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
SN 0929-5305
J9 J THROMB THROMBOLYS
JI J. Thromb. Thrombolysis
PD DEC
PY 2008
VL 26
IS 3
BP 243
EP 247
DI 10.1007/s11239-007-0162-1
PG 5
WC Hematology; Peripheral Vascular Disease
SC Hematology; Cardiovascular System & Cardiology
GA 371NQ
UT WOS:000260838400011
PM 17982734
ER
PT J
AU Sidawy, AN
Aidinian, G
Johnson, ON
White, PW
DeZee, KJ
Henderson, WG
AF Sidawy, Anton N.
Aidinian, Gilbert
Johnson, Owen N., III
White, Paul W.
DeZee, Kent J.
Henderson, William G.
TI Effect of chronic renal insufficiency on outcomes of carotid
endarterectomy
SO JOURNAL OF VASCULAR SURGERY
LA English
DT Article; Proceedings Paper
CT 21st Annual Meeting of the Eastern-Vascular-Society
CY SEP 27-29, 2007
CL Baltimore, MD
SP Eastern Vasc Soc
ID GLOMERULAR-FILTRATION-RATE; CHRONIC KIDNEY-DISEASE; HIGH-RISK; SERUM
CREATININE; SYMPTOMATIC PATIENTS; MORTALITY; STENOSIS; DYSFUNCTION;
PROTOCOLS; TRIAL
AB Objective: Conflicting data exist regarding the effect of chronic renal insufficiency (CRI) on carotid endarterectomy (CEA) outcomes. A large database was used to analyze the effect of CRI, defined by glomerular filtration rate (GFR), as an independent risk factor of CEA.
Methods: Prospectively collected data regarding CEAs performed at 123 Veterans Affairs Medical Centers as part of the National Surgical Quality Improvement Program were retrospectively analyzed. Renal function was used to divide patients into three CRI groups: normal or mild (control; GFR >= 60 mL/min/1.73 m(2)), moderate (GFR 30 to 59), and severe (GFR <30). Bivariate analysis and multivariate logistic regression were used to characterize risk factors and their associations with 30-day morbidity and mortality.
Results: Between Jan 1, 1996, and Dec 31, 2003, 22,080 patients underwent CEA. Patients missing creatinine levels, already dialysis-dependent, or in acute renal failure just before surgery were excluded. This left 20,899 available for analysis, of which 13,965 had a GFR of >= 60, 6,423 had a GFR of 30 to 59, and 511 had a GFR of <30. The incidence of neurologic complications did not differ significantly (control, 1.7%; moderate CRI, 1.9%; severe CRI, 2.7%). The moderate CRI group experienced significantly more cardiac events (1.7% vs 0.9% for controls, P < .001). This remained predictive in the multivariate model even adjusting for all other risk factors (adjusted odds ratio [AOR], 1.6; 95% confidence interval [CI] 1.1-2.3; P = .009). The moderate CRI group also had higher rates of pulmonary complications (2.1% vs 1.3% control; P < .001; AOR, 1.3; 95% CI, 1.0-1.7; P = .031) but not 30-day mortality (P = .269). Those with severe CRI had a much higher mortality (3.1% vs 1.0% control, P < .001), which remained significant in the multivariate model (AOF, 2.7; 95% CI, 1.6-4.8; P < .001).
Conclusion: Although impaired renal function does not independently increase the risk of neurologic or infections complications, CRI is a significant negative independent risk factor in predicting other outcomes after CEA. Patients with moderate CRI (GFR, 30-59 mL/min/1.73 m(2)) are at increased risk for cardiac and pulmonary morbidity, but not death, and those with severe CRI (GFR <30 mL/min/1.73 m(2)) have a much higher operative mortality. Patients with CRI should be carefully evaluated before CEA to optimize existing cardiac and pulmonary disease. Understanding this increased risk may assist the surgeon in preoperative counseling and perioperative management. (J Vasc Surg 2008;48:1423-30.)
C1 [Sidawy, Anton N.] George Washington Univ, Dept Surg, Washington, DC USA.
[Sidawy, Anton N.; Aidinian, Gilbert; Johnson, Owen N., III; White, Paul W.] Vet Affairs Med Ctr, Surg Serv, Washington, DC 20422 USA.
[Sidawy, Anton N.; Henderson, William G.] Georgetown Univ, Washington, DC 20057 USA.
[Aidinian, Gilbert; Johnson, Owen N., III; White, Paul W.; DeZee, Kent J.] Walter Reed Army Med Ctr, Washington, DC 20307 USA.
[Sidawy, Anton N.; Henderson, William G.] Univ Colorado, Hlth Outcomes Program, Denver, CO 80202 USA.
RP Sidawy, AN (reprint author), 50 Irving St,NW 112, Washington, DC 20422 USA.
EM ansidawy@aol.com
OI Johnson III, Owen/0000-0001-6497-1285
NR 32
TC 33
Z9 34
U1 0
U2 2
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0741-5214
J9 J VASC SURG
JI J. Vasc. Surg.
PD DEC
PY 2008
VL 48
IS 6
BP 1423
EP 1430
DI 10.1016/j.jvs.2008.07.006
PG 8
WC Surgery; Peripheral Vascular Disease
SC Surgery; Cardiovascular System & Cardiology
GA 388FX
UT WOS:000262006800011
PM 18829214
ER
PT J
AU O'Guinn, ML
Klein, TA
Lee, JS
Kim, HC
Baek, LJ
Chong, ST
Turell, MJ
Burkett, DA
Schuster, A
Lee, IY
Yi, SH
Sames, WJ
Song, KJ
Song, FW
AF O'Guinn, Monica L.
Klein, Terry A.
Lee, John S.
Kim, Heung-Chul
Baek, Luck-Ju
Chong, Sung-Tae
Turell, Michael J.
Burkett, Douglas A.
Schuster, Anthony
Lee, In-Yong
Yi, Suk-Hee
Sames, William J.
Song, Ki-Joon
Song, Fin-Won
TI Ecological surveillance of small mammals at Firing Points 10 and 60,
Gyeonggi Province, Republic of Korea, 2001-2005
SO JOURNAL OF VECTOR ECOLOGY
LA English
DT Article
DE Rodents; insectivores; ecology; Korea; Apodemus; Rattus; Micromys;
Microtus; Myodes (= Eothenomys); Tscherskia (= Cricetulus)
ID SIN-NOMBRE-VIRUS; APODEMUS-AGRARIUS; RODENT POPULATIONS;
HEMORRHAGIC-FEVER; ETIOLOGIC AGENT; SOUTH-KOREA; INFECTION;
TRANSMISSION; SEOUL; RATS
AB Throughout Korea, small mammals are hosts to a number of disease-causing agents that pose a health threat to US. and Korean military forces while they conduct field-training exercises. A seasonal rodent-borne disease surveillance program was established at two firing points (FP), FP-10, and FP-60, and conducted over five years from 2001 through 2005 in response to hantavirus cases among US. soldiers. The ecology of these sites consisted primarily of tall grasses associated with semi-permanent and temporary water sources (drainage ditches and a small stream) and dry-land agriculture farming. Eight species of rodents and one species of insectivore were collected, including Apodemus agrarius, Micromys minutus, Mus musculus, Rattus norvegicus, Tscherskia triton, Microtus fortis, Myodes regulus, and Crocidura lasiura. The striped field mouse, A. agrarius, (primary reservoir for Hantaan virus, the causative agent of Korean hemorrhagic fever), was the most frequently collected, representing 90.6% of the 1,288 small mammals captured at both sites. Reported herein are the ecological parameters, seasonal population densities, and seasonal population characteristics associated with small mammals collected at two military training sites in the Republic of Korea. Journal of Vector Ecology 33 (2): 370-384. 2008.
C1 [Baek, Luck-Ju; Song, Ki-Joon; Song, Fin-Won] Korea Univ, Coll Med, Dept Microbiol, Seoul 136705, South Korea.
[O'Guinn, Monica L.; Lee, John S.; Turell, Michael J.] USA, Dept Virol, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA.
[Klein, Terry A.; Yi, Suk-Hee] 18 Med Command, Unit 15281, APO, AP 96205 USA.
[Kim, Heung-Chul; Song, Fin-Won] 18 Med Command, Unit 15247, APO, AP 96205 USA.
[Burkett, Douglas A.] Air Force Inst Operat Hlth, Unit 5213, Okinawa, Japan.
[Schuster, Anthony] US Ctr Hlth Promot & Prevent Med S, Atlanta, GA 30330 USA.
[Lee, In-Yong] Yonsei Univ, Coll Med, Dept Environm Med Biol, Seoul 120749, South Korea.
[Sames, William J.] Def Logist Agcy, Ft Belvoir, VA 22060 USA.
RP Song, FW (reprint author), Korea Univ, Coll Med, Dept Microbiol, 126-1,5Ka, Seoul 136705, South Korea.
RI Valle, Ruben/A-7512-2013
FU US. Department of Defense Global Emerging Infections Surveillance and
Response System (GEIS); Armed Forces Medical Intelligence Center, Fort
Detrick
FX We acknowledge the assistance of Wan-Young Kim, Edwin Huertas, and Kerry
McKinley for their support in coordinating personnel for conducting
rodent surveillance. We also thank the many soldiers of the Preventive
Medicine Detachments, 168th Multifunctional Medical
Battalion, for their support in conducting rodent surveillance
throughout the five-year surveillance program. We especially thank
Se-Hun Gu, So-Hee Shim, Hae-Ji Kang, and other graduate students and
staff of Korea University for their support in handling and gathering of
small mammal bionomics in the laboratory. We are grateful for the
support and encouragement that the 18th MEDCOM commanders,
Phillip Volpe and Brian Allgood (deceased), and their preventive
medicine consultant Hee-Choon Lee provided throughout this study.;
Research was performed in compliance with the Animal Welfare Act and
other federal statues and regulations relating to animals and
experiments involving animals and adhered to principles stated in the
guide for the Care and Use of Laboratory Animals, National Research
Council, 1996. Funding for portions of this work was provided by the US.
Department of Defense Global Emerging Infections Surveillance and
Response System (GEIS), Silver Spring, MD, and the Armed Forces Medical
Intelligence Center, Fort Detrick, MD. The views expressed in this
article are those of the authors and do not reflect the official policy
or position of the Department of Defense, the Department of the Army, or
the U.S. Government.
NR 51
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U1 1
U2 2
PU SOC VECTOR ECOLOGY
PI CORONA
PA 1966 COMPTON AVE, CORONA, CA 92881 USA
SN 1081-1710
EI 1948-7134
J9 J VECTOR ECOL
JI J. Vector Ecol.
PD DEC
PY 2008
VL 33
IS 2
BP 370
EP 384
PG 15
WC Entomology
SC Entomology
GA 395LB
UT WOS:000262524500020
PM 19263858
ER
PT J
AU Rueda, LM
Pecor, JE
Lowen, RG
Carder, M
AF Rueda, Leopoldo M.
Pecor, James E.
Lowen, Robert G.
Carder, Mark
TI New record and updated checklists of the mosquitoes of Afghanistan and
Iraq
SO JOURNAL OF VECTOR ECOLOGY
LA English
DT Article
C1 [Rueda, Leopoldo M.; Pecor, James E.] Walter Reed Army Inst Res, Walter Reed Biosystemat Unit, Div Entomol, Silver Spring, MD 20910 USA.
[Lowen, Robert G.] USA, Ctr Hlth Promot & Prevent Med, Attn MCHB AN ES, Ft George G Meade, MD 20755 USA.
[Carder, Mark] US AMEDD Ctr & Sch, Attn MCCS HPM, Acad Hlth Sci, Med Zool Branch, Ft Sam Houston, TX 78234 USA.
RP Rueda, LM (reprint author), Walter Reed Army Inst Res, Walter Reed Biosystemat Unit, Div Entomol, Silver Spring, MD 20910 USA.
NR 23
TC 3
Z9 3
U1 0
U2 3
PU SOC VECTOR ECOLOGY
PI CORONA
PA 1966 COMPTON AVE, CORONA, CA 92881 USA
SN 1081-1710
J9 J VECTOR ECOL
JI J. Vector Ecol.
PD DEC
PY 2008
VL 33
IS 2
BP 397
EP 402
PG 6
WC Entomology
SC Entomology
GA 395LB
UT WOS:000262524500024
PM 19263862
ER
PT J
AU Klungthong, C
Putnak, R
Mammen, MP
Li, T
Zhang, C
AF Klungthong, C.
Putnak, R.
Mammen, M. P.
Li, T.
Zhang, C.
TI Molecular genotyping of dengue viruses by phylogenetic analysis of the
sequences of individual genes
SO JOURNAL OF VIROLOGICAL METHODS
LA English
DT Article
DE Dengue viruses; Diversity; Genotyping; Individual genes
ID NATURAL-POPULATIONS; CRYSTAL-STRUCTURE; TYPE-2 VIRUS; EVOLUTION;
EPIDEMIOLOGY; RECOMBINATION; VENEZUELA; THAILAND
AB The prevalence of four serotypes of dengue virus (DENV) has risen dramatically in recent years accompanied by an increase in viral genetic diversity. The evolution of DENV has had a major impact on their virulence for humans and on the epidemiology of dengue disease around the world. In order to perform disease surveillance and understand DENV evolution and its effects on virus transmission and disease, an efficient and accurate method for genotype identification is required. Phylogenetic analysis of viral gene sequences is the method used most commonly, with envelope (E) gene the most frequently selected target. To determine which gene might be suitable targets for genotyping DENV, phylogenetic analysis was performed on 10 individual coding genes plus the T-non-translated region (TNTR) for 56 geographically divergent DENV strains representing all identified genotypes. These were reflected in eleven maximum likelihood phylogenetic trees. Based on the bootstrap values (over 90%) supporting the major nodes, the best target genes were identified for each serotype: for DENV-1, the sequences of all coding genes except non-structural gene 4A (NS4A), for DENV-2, PrM/M, E, NS1, NS3, NS4A and NS5, for DENV-3, all coding genes and the TNTR, and for DENV-4, C, PrM/M, E, NS1, NS2A, NS2B, NS4A and NS5. Published by Elsevier B.V.
C1 [Putnak, R.; Li, T.; Zhang, C.] Walter Reed Army Inst Res, Div Viral Dis, Silver Spring, MD 20910 USA.
[Klungthong, C.; Mammen, M. P.; Zhang, C.] USA, Med Component Armed Forces Res Inst Med Sci, Dept Virol, Bangkok, Thailand.
RP Zhang, C (reprint author), Walter Reed Army Inst Res, Div Viral Dis, Silver Spring, MD 20910 USA.
EM chunlin.zhang@amedd.army.mil
FU Military Infectious Disease Research Program (MIDRP); United States Army
Medical Research and Materiel Command, Fort Detrick
FX This work was funded by the Military Infectious Disease Research Program
(MIDRP) and the United States Army Medical Research and Materiel
Command, Fort Detrick, MD. The opinions or assertions contained herein
are the private views of the authors and are not to be construed as
reflecting the official views of the United States Army or the
Department of Defense.
NR 32
TC 27
Z9 28
U1 0
U2 4
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0166-0934
J9 J VIROL METHODS
JI J. Virol. Methods
PD DEC
PY 2008
VL 154
IS 1-2
BP 175
EP 181
DI 10.1016/j.jviromet.2008.07.021
PG 7
WC Biochemical Research Methods; Biotechnology & Applied Microbiology;
Virology
SC Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology;
Virology
GA 385UJ
UT WOS:000261838800025
PM 18778736
ER
PT J
AU Redden, ES
Elliott, LR
Pettitt, RA
Carstens, CB
AF Redden, Elizabeth S.
Elliott, Linda R.
Pettitt, Rodger A.
Carstens, Christian B.
TI A tactile option to reduce robot controller size
SO JOURNAL ON MULTIMODAL USER INTERFACES
LA English
DT Article
DE Robot control; Mobile computing; Haptic; design; Human-computer
interface; Tactile display; Split screen displays
AB In response to operational requirements for smaller robotic controller devices for use by dismounted US Army soldiers, three types of robot controller navigation map display configurations were evaluated for effects on beyond line-of-sight robotic navigation tasks. We predicted better performance with the larger split screen display that presents both a map display and a camera-based driving display on a 6.5 inch screen. Two smaller alternatives were also evaluated. One alternative was a 3.5 inch display that allowed the operator to toggle back and forth between the driving display and the map display. The third option added a torso-mounted tactile display to the toggle-based display in order to provide direction information simultaneously with the camera display and thus reduce the need to toggle as frequently to the map display. Each display option was evaluated based on objective performance data, expert-based observations, and scaled subjective soldier questionnaire items. Findings indicated that operators' navigation performance with the multimodal 3.5 inch toggle display was as effective as their performance with a 6.5 inch split screen display. Operator performance was significantly lower with the 3.5 inch toggle display that did not have the tactile display.
C1 [Redden, Elizabeth S.; Elliott, Linda R.; Pettitt, Rodger A.; Carstens, Christian B.] USA, Res Lab, USAIC Human Res & Engn Field Element, Ft Benning, GA USA.
RP Elliott, LR (reprint author), USA, Res Lab, USAIC Human Res & Engn Field Element, Bldg 4,Rm 59, Ft Benning, GA USA.
EM Linda.r.elliott@us.army.mil
NR 29
TC 1
Z9 1
U1 0
U2 1
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1783-7677
J9 J MULTIMODAL USER IN
JI J. Multimodal User Interfaces
PD DEC
PY 2008
VL 2
IS 3-4
BP 205
EP 216
DI 10.1007/s12193-009-0019-3
PG 12
WC Computer Science, Artificial Intelligence; Computer Science, Cybernetics
SC Computer Science
GA V26HO
UT WOS:000208536900006
ER
PT J
AU Hannah, ST
Avolio, BJ
Luthans, F
Harms, PD
AF Hannah, Sean T.
Avolio, Bruce J.
Luthans, Fred
Harms, P. D.
TI Leadership efficacy: Review and future directions
SO LEADERSHIP QUARTERLY
LA English
DT Review
DE Leader efficacy; Agency; Collective efficacy; Means efficacy; Leadership
ID SOCIAL-COGNITIVE THEORY; POSITIVE ORGANIZATIONAL-BEHAVIOR; COMPLEX
DECISION-MAKING; PERCEIVED SELF-EFFICACY; TRANSFORMATIONAL LEADERSHIP;
COLLECTIVE-EFFICACY; GOAL ORIENTATION; CHARISMATIC LEADERSHIP;
PERFORMANCE FEEDBACK; PERSONALITY-TRAITS
AB The concept of leader efficacy has received relatively little attention in the leadership literature. This is somewhat surprising given that effective leadership requires high levels of agency (i.e., deliberately or intentionally exerting positive influence) and confidence. This review uses existing theory and research on leader efficacy as a point of departure for proposing an expanded and multi-level framework for understanding the domain of leadership efficacy that includes leader, follower, and collective efficacies. The primary goals are to provide a conceptual framework to stimulate future theory and research on building efficacious leadership and to understand how such leadership develops and has implications for effective performance. Published by Elsevier Inc.
C1 [Hannah, Sean T.] US Mil Acad, Dept Behav Sci & Leadership, West Point, NY 10996 USA.
[Avolio, Bruce J.] Univ Washington, Foster Business Sch, Dept Management & Org, Seattle, WA 98195 USA.
[Luthans, Fred; Harms, P. D.] Univ Nebraska, Coll Business Adm, Dept Management, Lincoln, NE 68588 USA.
RP Hannah, ST (reprint author), US Mil Acad, Dept Behav Sci & Leadership, West Point, NY 10996 USA.
EM Sean.hannah@usma.edu
NR 220
TC 67
Z9 68
U1 6
U2 94
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1048-9843
EI 1873-3409
J9 LEADERSHIP QUART
JI Leadersh. Q.
PD DEC
PY 2008
VL 19
IS 6
BP 669
EP 692
DI 10.1016/j.leaqua.2008.09.007
PG 24
WC Psychology, Applied; Management
SC Psychology; Business & Economics
GA 379AJ
UT WOS:000261366300004
ER
PT J
AU Burgess, EB
AF Burgess, Edwin B.
TI My Private War: Liberated Body, Captive Mind; A World War II POW's
Journey
SO LIBRARY JOURNAL
LA English
DT Book Review
C1 [Burgess, Edwin B.] USA, Combined Arms Res Lib, Ft Leavenworth, KS USA.
RP Burgess, EB (reprint author), USA, Combined Arms Res Lib, Ft Leavenworth, KS USA.
NR 1
TC 0
Z9 0
U1 0
U2 0
PU REED BUSINESS INFORMATION
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010 USA
SN 0363-0277
J9 LIBR J
JI Libr. J.
PD DEC
PY 2008
VL 133
IS 20
BP 135
EP 136
PG 2
WC Information Science & Library Science
SC Information Science & Library Science
GA 382KJ
UT WOS:000261604400200
ER
PT J
AU Stephenson, LD
Kumar, A
AF Stephenson, L. D.
Kumar, Ashok
TI CASE HISTORY Advanced Coatings for Water Treatment Plant Components
SO MATERIALS PERFORMANCE
LA English
DT Article
AB Components of water treatment plants (WTPs) are susceptible to corrosion from constant immersion in water A case history of corrosion and proximity to chlorine. problems and their treatment at an Army WTP is presented Solutions included using high micro-silica restoration mortar and advanced coal tar epoxy coatings.
C1 [Stephenson, L. D.; Kumar, Ashok] USA, Erdc, CERL, Champaign, IL 61826 USA.
RP Stephenson, LD (reprint author), USA, Erdc, CERL, POB 9005, Champaign, IL 61826 USA.
NR 5
TC 1
Z9 1
U1 0
U2 1
PU NATL ASSOC CORROSION ENG
PI HOUSTON
PA 1440 SOUTH CREEK DRIVE, HOUSTON, TX 77084-4906 USA
SN 0094-1492
J9 MATER PERFORMANCE
JI Mater. Perform.
PD DEC
PY 2008
VL 47
IS 12
BP 40
EP 45
PG 6
WC Materials Science, Characterization & Testing
SC Materials Science
GA 381NT
UT WOS:000261543900009
ER
PT J
AU Vecherin, SN
Ostashev, VE
Wilson, DK
Ziemann, A
AF Vecherin, Sergey N.
Ostashev, Vladimir E.
Wilson, D. Keith
Ziemann, A.
TI Time-dependent stochastic inversion in acoustic tomography of the
atmosphere with reciprocal sound transmission
SO MEASUREMENT SCIENCE AND TECHNOLOGY
LA English
DT Article
DE travel-time tomography; inverse problems; acoustic imaging; remote
sensing; tomography of the atmosphere; stochastic inversion
ID KALMAN FILTER; VECTOR-FIELDS; SURFACE-LAYER; RECONSTRUCTION;
TEMPERATURE; RESTORATION; TURBULENCE; FLOW
AB Time-dependent stochastic inversion (TDSI) was recently developed for acoustic travel-time tomography of the atmosphere. This type of tomography allows reconstruction of temperature and wind-velocity fields given the location of sound sources and receivers and the travel times between all source-receiver pairs. The quality of reconstruction provided by TDSI depends on the geometry of the transducer array. However, TDSI has not been studied for the geometry with reciprocal sound transmission. This paper is focused on three aspects of TDSI. First, the use of TDSI in reciprocal sound transmission arrays is studied in numerical and physical experiments. Second, efficiency of time-dependent and ordinary stochastic inversion ( SI) algorithms is studied in numerical experiments. Third, a new model of noise in the input data for TDSI is developed that accounts for systematic errors in transducer positions. It is shown that (i) a separation of the travel times into temperature and wind-velocity components in tomography with reciprocal transmission does not improve the reconstruction, (ii) TDSI yields a better reconstruction than SI and (iii) the developed model of noise yields an accurate reconstruction of turbulent fields and estimation of errors in the reconstruction.
C1 [Vecherin, Sergey N.; Ostashev, Vladimir E.] New Mexico State Univ, Dept Phys, Las Cruces, NM 88003 USA.
[Vecherin, Sergey N.] USA, Signature Phys Branch, Erdc, CRREL, Hanover, NH 03755 USA.
[Ostashev, Vladimir E.] NOAA, Earth Syst Res Lab, Boulder, CO 80305 USA.
[Ziemann, A.] Univ Leipzig, Inst Meteorol, D-04103 Leipzig, Germany.
RP Vecherin, SN (reprint author), USA, Signature Phys Branch, Erdc, CRREL, 72 Lyme Rd, Hanover, NH 03755 USA.
EM Sergey.N.Vecherin@usace.army.mil
RI Wilson, D. Keith/A-4687-2012
OI Wilson, D. Keith/0000-0002-8020-6871
NR 39
TC 4
Z9 4
U1 1
U2 3
PU IOP PUBLISHING LTD
PI BRISTOL
PA TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND
SN 0957-0233
EI 1361-6501
J9 MEAS SCI TECHNOL
JI Meas. Sci. Technol.
PD DEC
PY 2008
VL 19
IS 12
AR 125501
DI 10.1088/0957-0233/19/12/125501
PG 12
WC Engineering, Multidisciplinary; Instruments & Instrumentation
SC Engineering; Instruments & Instrumentation
GA 370JR
UT WOS:000260759000015
ER
PT J
AU Desyatova, AS
Zhigalov, MV
Krys'ko, VA
Saltykova, OA
AF Desyatova, A. S.
Zhigalov, M. V.
Krys'ko, V. A.
Saltykova, O. A.
TI Dissipative dynamics of geometrically nonlinear Bernoulli-Euler beams
SO MECHANICS OF SOLIDS
LA English
DT Article
ID COMPLEX PARAMETRIC VIBRATIONS; PLATES; BIFURCATIONS
AB We consider nonlinear dissipative vibrations of the Bernoulli-Euler beam. We find that, under the action of a transverse alternating load, the vibrations may become chaotic. We study a scenario in which harmonic vibrations become chaotic, namely, the Feigenbaum scenario, and find the Feigenbaumconstant. In the present paper, we paymuch attention to the reliability of the results obtained. To this end, we use two methods, the finite difference O(h (2)) method and the finite element method in the Bubnov-Galerkin form, and verify the convergence of these methods.
C1 [Desyatova, A. S.] USA, Washington, DC 20310 USA.
[Zhigalov, M. V.; Krys'ko, V. A.; Saltykova, O. A.] Saratov State Tech Univ, Saratov 410054, Russia.
RP Desyatova, AS (reprint author), USA, Washington, DC 20310 USA.
EM desyatova@mail.ru; ZhigalovM@yandex.ru; tak@san.ru;
olga_a_saltykova@mail.ru
OI Krysko, V.A./0000-0002-4914-764X
FU Russian Foundation for Basic Research [06-08-01357a]
FX The research was supported by the Russian Foundation for Basic Research,
grant no. 06-08-01357a.
NR 15
TC 1
Z9 1
U1 1
U2 7
PU ALLERTON PRESS INC
PI NEW YORK
PA 18 WEST 27TH ST, NEW YORK, NY 10001 USA
SN 0025-6544
J9 MECH SOLIDS+
JI Mech. Sol.
PD DEC
PY 2008
VL 43
IS 6
BP 948
EP 956
DI 10.3103/S0025654408060125
PG 9
WC Mechanics
SC Mechanics
GA 397QB
UT WOS:000262676100012
ER
PT J
AU Nelson, MWJ
AF Nelson, Major William J.
TI A RIGHT WAY AND A WRONG WAY: REMEDYING EXCESSIVE POST-TRIAL DELAY IN
LIGHT OF TARDIF, MORENO, AND TOOHEY
SO MILITARY LAW REVIEW
LA English
DT Article
C1 USA, Washington, DC 20310 USA.
RP Nelson, MWJ (reprint author), USA, Washington, DC 20310 USA.
NR 5
TC 0
Z9 0
U1 0
U2 0
PU JUDGE ADVOCATE GENERALS SCHOOL
PI CHARLOTTESVILLE
PA US ARMY, CHARLOTTESVILLE, VA 22903-1781 USA
SN 0026-4040
J9 MIL LAW REV
JI Milit. Law Rev.
PD WIN
PY 2008
VL 198
BP 1
EP 66
PG 66
WC Law
SC Government & Law
GA 405DD
UT WOS:000263201900001
ER
PT J
AU Kiel, JL
AF Kiel, John Lopan, Jr.
TI CROSSING THE LINE: RECONCILING THE RIGHT TO PICKET MILITARY FUNERALS
WITH THE FIRST AMENDMENT
SO MILITARY LAW REVIEW
LA English
DT Article
C1 USA, Washington, DC 20310 USA.
RP Kiel, JL (reprint author), USA, Washington, DC 20310 USA.
NR 9
TC 1
Z9 1
U1 0
U2 0
PU JUDGE ADVOCATE GENERALS SCHOOL
PI CHARLOTTESVILLE
PA US ARMY, CHARLOTTESVILLE, VA 22903-1781 USA
SN 0026-4040
J9 MIL LAW REV
JI Milit. Law Rev.
PD WIN
PY 2008
VL 198
BP 67
EP 115
PG 49
WC Law
SC Government & Law
GA 405DD
UT WOS:000263201900002
ER
PT J
AU Marsh, JJ
AF Marsh, J. Jeremy
TI LEX LATA OR LEX FERENDA? RULE 45 OF THE ICRC STUDY ON CUSTOMARY
INTERNATIONAL HUMANITARIAN LAW
SO MILITARY LAW REVIEW
LA English
DT Article
RP Marsh, JJ (reprint author), USA, TJAGLCS, Int & Operat Law Dept, Charlottesville, VA USA.
NR 11
TC 2
Z9 2
U1 1
U2 1
PU JUDGE ADVOCATE GENERALS SCHOOL
PI CHARLOTTESVILLE
PA US ARMY, CHARLOTTESVILLE, VA 22903-1781 USA
SN 0026-4040
J9 MIL LAW REV
JI Milit. Law Rev.
PD WIN
PY 2008
VL 198
BP 116
EP 164
PG 49
WC Law
SC Government & Law
GA 405DD
UT WOS:000263201900003
ER
PT J
AU Lowery, TE
AF Lowery, Tyesha E.
TI ONE "GET OUT OF JAIL FREE" CARD: SHOULD PROBATION BE AN AUTHORIZED
COURTS-MARTIAL PUNISHMENT?
SO MILITARY LAW REVIEW
LA English
DT Article
C1 USA, TJAGLCS, Washington, DC 20310 USA.
RP Lowery, TE (reprint author), USA, TJAGLCS, Washington, DC 20310 USA.
NR 15
TC 3
Z9 3
U1 0
U2 0
PU JUDGE ADVOCATE GENERALS SCHOOL
PI CHARLOTTESVILLE
PA US ARMY, CHARLOTTESVILLE, VA 22903-1781 USA
SN 0026-4040
J9 MIL LAW REV
JI Milit. Law Rev.
PD WIN
PY 2008
VL 198
BP 165
EP 209
PG 45
WC Law
SC Government & Law
GA 405DD
UT WOS:000263201900004
ER
PT J
AU Gavula, BP
AF Gavula, Brian P.
TI THE TERROR PRESIDENCY: LAW AND JUDGMENT INSIDE THE BUSH ADMINISTRATION
SO MILITARY LAW REVIEW
LA English
DT Article
C1 USA, Judge Advocate Gen Legal Ctr & Sch, Judge Advocate Officer Grad Course 57, Charlottesville, VA USA.
RP Gavula, BP (reprint author), USA, Judge Advocate Gen Legal Ctr & Sch, Judge Advocate Officer Grad Course 57, Charlottesville, VA USA.
NR 8
TC 0
Z9 0
U1 1
U2 1
PU JUDGE ADVOCATE GENERALS SCHOOL
PI CHARLOTTESVILLE
PA US ARMY, CHARLOTTESVILLE, VA 22903-1781 USA
SN 0026-4040
J9 MIL LAW REV
JI Milit. Law Rev.
PD WIN
PY 2008
VL 198
BP 210
EP 218
PG 9
WC Law
SC Government & Law
GA 405DD
UT WOS:000263201900005
ER
PT J
AU Kwon, WH
AF Kwon, Walter H.
TI THE POST-AMERICAN WORLD
SO MILITARY LAW REVIEW
LA English
DT Article
C1 USA, Judge Advocate Officer Grad Course 57, Judge Advocate Gen Legal Ctr & Sch, Charlottesville, VA USA.
RP Kwon, WH (reprint author), USA, Judge Advocate Officer Grad Course 57, Judge Advocate Gen Legal Ctr & Sch, Charlottesville, VA USA.
NR 16
TC 0
Z9 0
U1 0
U2 0
PU JUDGE ADVOCATE GENERALS SCHOOL
PI CHARLOTTESVILLE
PA US ARMY, CHARLOTTESVILLE, VA 22903-1781 USA
SN 0026-4040
J9 MIL LAW REV
JI Milit. Law Rev.
PD WIN
PY 2008
VL 198
BP 219
EP 226
PG 8
WC Law
SC Government & Law
GA 405DD
UT WOS:000263201900006
ER
PT J
AU Hutchinson, JW
Greene, JP
Hansen, SL
AF Hutchinson, Jeffrey W.
Greene, Jeffery P.
Hansen, Shana L.
TI Evaluating Active Duty Risk-Taking: Military Home, Education, Activity,
Drugs, Sex, Suicide, and Safety Method
SO MILITARY MEDICINE
LA English
DT Article
AB Psychosocial screening tools are routinely used by adolescent medicine providers to evaluate risk-taking behaviors and resiliency. A large number of U.S. military service members are adolescents, and many engage in behaviors that cause morbidity and death, such as tobacco use and binge drinking. Health care providers should consider the regular use of a psychosocial screening method to evaluate risk-taking behavior. The Home, Education, Activity, Drugs, Sex, Suicide, and Safety method is used to evaluate the home environment, educational and employment situations, activities, drug use, sexual activity, suicide, and safety during health care visits. This technique, originally created for a civilian adolescent population, can be used with minimal adjustments to evaluate behaviors of military service members.
C1 [Hutchinson, Jeffrey W.] Walter Reed Army Med Ctr, Adolescent Med Dept, Washington, DC 20307 USA.
[Greene, Jeffery P.] Tripler Army Med Ctr, Adolescent Med Dept, Honolulu, HI 96859 USA.
[Hansen, Shana L.] Brooke Army Med Ctr, Adolescent Med Dept, Ft Sam Houston, TX 78234 USA.
RP Hutchinson, JW (reprint author), Walter Reed Army Med Ctr, Adolescent Med Dept, Washington, DC 20307 USA.
NR 39
TC 7
Z9 7
U1 1
U2 1
PU ASSOC MILITARY SURG US
PI BETHESDA
PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA
SN 0026-4075
J9 MIL MED
JI Milit. Med.
PD DEC
PY 2008
VL 173
IS 12
BP 1164
EP 1167
PG 4
WC Medicine, General & Internal
SC General & Internal Medicine
GA V11ZO
UT WOS:000207569700006
PM 19149332
ER
PT J
AU Ivins, BJ
Crowley, JS
Johnson, J
Warden, DL
Schwab, KA
AF Ivins, Brian J.
Crowley, John S.
Johnson, Jeffrey
Warden, Deborah L.
Schwab, Karen A.
TI Traumatic Brain Injury Risk While Parachuting: Comparison of the
Personnel Armor System for Ground Troops Helmet and the Advanced Combat
Helmet
SO MILITARY MEDICINE
LA English
DT Article
AB Military paratroopers are inherently at risk for a variety of injuries when they jump, including traumatic brain injuries (TBIs). U.S. Army paratroopers rely on their ballistic helmets for protection against TBIs when jumping. Currently, two different helmets are available to Army paratroopers, that is, the personnel armor system for ground troops helmet and the advanced combat helmet. This study compared the incidence of self-reported, jump-related TBIs in a small sample of paratroopers (N = 585) using each type of helmet. Data were obtained from surveys of soldiers at Fort Bragg, North Carolina. The overall relative risk of sustaining a TBI while jumping was 2.3 times (95% confidence interval, 1.3-4.3) higher for personnel armor system for ground troops helmet users. Most of the increase in risk was accounted for by the most-minor TBIs (American Academy of Neurology grade I or 2 concussion).
C1 [Ivins, Brian J.; Warden, Deborah L.; Schwab, Karen A.] Walter Reed Army Med Ctr, Def & Vet Brain Injury Ctr, Washington, DC 20307 USA.
[Crowley, John S.] USA, Aeromed Res Lab, Ft Rucker, AL 36362 USA.
[Johnson, Jeffrey] Irwin Army Community Hosp, Ft Riley, KS 66442 USA.
RP Ivins, BJ (reprint author), Walter Reed Army Med Ctr, Def & Vet Brain Injury Ctr, Washington, DC 20307 USA.
NR 19
TC 3
Z9 3
U1 0
U2 1
PU ASSOC MILITARY SURG US
PI BETHESDA
PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA
SN 0026-4075
J9 MIL MED
JI Milit. Med.
PD DEC
PY 2008
VL 173
IS 12
BP 1168
EP 1172
PG 5
WC Medicine, General & Internal
SC General & Internal Medicine
GA V11ZO
UT WOS:000207569700007
PM 19149333
ER
PT J
AU Bir, C
Barbir, A
Dosquett, F
Wilhelm, M
van der Horst, M
Wolfe, G
AF Bir, Cynthia
Barbir, Ana
Dosquett, Frank
Wilhelm, Marianne
van der Horst, Marike
Wolfe, Greg
TI Validation of Lower Limb Surrogates as Injury Assessment Tools in Floor
Impacts due to Anti-Vehicular Land Mines
SO MILITARY MEDICINE
LA English
DT Article
AB The aim of this study was to assess the ability of lower limb surrogates to predict injury due to floor/foot plate impact in military vehicles during anti-vehicular land mine explosions. Testing was conducted using two loading conditions simulated to represent those conditions created in the field. The lower condition was represented by a 24-kg mass impactor with a velocity of 4.7 m/s. The higher loading condition was represented by a 37-kg mass impactor with a velocity of 8.3 m/s. Two biomechanical surrogates were evaluated using the loading conditions: 50th percentile Hybrid III foot/ankle and Test Device for Human Occupant Restraint THOR-Lx. Comparisons of the force-time response were made to established corridors. Results show a better correlation to the corridors with the THOR-Lx; however, future improvements to the THOR-Lx are recommended.
C1 [Bir, Cynthia; Barbir, Ana; Wilhelm, Marianne] Wayne State Univ, Detroit, MI 48201 USA.
[Dosquett, Frank] Tech Ctr Weap & Ammunit, WTD 91, D-49716 Meppen, Germany.
[van der Horst, Marike] TNO Def Secur & Safety, NL-2280 AA Rijswijk, Netherlands.
[Wolfe, Greg] USA, RDECOM TARDEC, Warren, MI 48397 USA.
RP Bir, C (reprint author), Wayne State Univ, 818 W Hancock, Detroit, MI 48201 USA.
FU U.S. Army TACOM [W56HZV-05-P-L511]
FX Funding for this study was in part from U.S. Army TACOM Contract
W56HZV-05-P-L511.
NR 15
TC 9
Z9 10
U1 0
U2 1
PU ASSOC MILITARY SURG US
PI BETHESDA
PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA
SN 0026-4075
J9 MIL MED
JI Milit. Med.
PD DEC
PY 2008
VL 173
IS 12
BP 1180
EP 1184
PG 5
WC Medicine, General & Internal
SC General & Internal Medicine
GA V11ZO
UT WOS:000207569700009
PM 19149335
ER
PT J
AU Fulton, L
Starnes, W
Caouette, M
Whittaker, D
Ivanitskaya, L
AF Fulton, Larty
Starnes, William
Caouette, Marc
Whittaker, Donna
Ivanitskaya, Lana
TI Explaining and Forecasting Attrition in the Army Pharmacy Technician
Course
SO MILITARY MEDICINE
LA English
DT Article
AB The Army pharmacy technician (68Q) course trains similar to 260 students per year, with a mean graduation rate of 71.3%. In support of this course, a research team conducted a study using multiple analytical methods to evaluate, to explain, and potentially to forecast failures, because the 28.7% of students who do not graduate are associated with both opportunity and real costs. Results of this study indicated that largely uncontrollable population demographic characteristics, such as rank and enrollment status, along with controllable Armed Services Vocational Aptitude Battery skilled technical test scores, were related to graduation rates. The results of this study may be used to assist individuals at risk of failure or to establish additional admission criteria to increase the likelihood of success.
C1 [Fulton, Larty; Starnes, William; Caouette, Marc; Whittaker, Donna] USA, Med Dept Ctr & Sch, Ft Sam Houston, TX 78234 USA.
[Ivanitskaya, Lana] Cent Michigan Univ, Mt Pleasant, MI 48859 USA.
RP Fulton, L (reprint author), USA, Med Dept Ctr & Sch, Ft Sam Houston, TX 78234 USA.
RI Ivanitskaya, Lana/G-5385-2011
NR 5
TC 1
Z9 1
U1 1
U2 1
PU ASSOC MILITARY SURG US
PI BETHESDA
PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 USA
SN 0026-4075
J9 MIL MED
JI Milit. Med.
PD DEC
PY 2008
VL 173
IS 12
BP 1219
EP 1224
PG 6
WC Medicine, General & Internal
SC General & Internal Medicine
GA V11ZO
UT WOS:000207569700017
PM 19149343
ER
PT J
AU Query, P
AF Query, Patrick
TI Crooked Europe: The Verse Drama of W.H. Auden (and Company)
SO MODERN DRAMA
LA English
DT Article
DE W.H. Auden; verse drama; ritual; Europe; collaboration
AB In this essay I argue that the trajectory of W.H. Auden's short career in verse drama describes the impossibility of its own objective: the use of ritual to represent a coherent idea of Europe without invoking an objective historical or spiritual tradition. His verse plays, born out of a commitment to drama's ritual origins and potential, offer a useful measure of the difficulty of imagining European cultural cohesion in the interwar period. Auden's plays employ a host of formal strategies to recreate the conditions of ritual, with some success. Moreover, Auden's plays, especially those written in collaboration with Christopher Isherwood, also wrestle with the problem of European political and cultural atomization. The solutions the plays offer, while often dramatically compelling, ultimately do not move beyond the political limitations and cultural disorders they describe, a shortcoming Auden later came to see in terms of the absence of tradition.
C1 US Mil Acad, West Point, NY 10996 USA.
RP Query, P (reprint author), US Mil Acad, West Point, NY 10996 USA.
NR 33
TC 1
Z9 1
U1 0
U2 0
PU UNIV TORONTO PRESS INC
PI TORONTO
PA JOURNALS DIVISION, 5201 DUFFERIN ST, DOWNSVIEW, TORONTO, ON M3H 5T8,
CANADA
SN 0026-7694
J9 MOD DRAMA
JI Mod. Drama
PD WIN
PY 2008
VL 51
IS 4
BP 579
EP 604
DI 10.3138/md.51.4.579
PG 26
WC Theater
SC Theater
GA 415ND
UT WOS:000263939700007
ER
PT J
AU Evans, AF
Wertheimer, RH
Keefer, ML
Boggs, CT
Peery, CA
Collis, K
AF Evans, Allen F.
Wertheimer, Robert H.
Keefer, Matthew L.
Boggs, Charles T.
Peery, Christopher A.
Collis, Ken
TI Transportation of Steelhead Kelts to Increase Iteroparity in the
Columbia and Snake Rivers
SO NORTH AMERICAN JOURNAL OF FISHERIES MANAGEMENT
LA English
DT Article
ID LIFE-HISTORY CHARACTERISTICS; TROUT SALMO-GAIRDNERI; ATLANTIC SALMON;
ONCORHYNCHUS-MYKISS; HATCHERY; SALAR; FISH; WILD; VARIABILITY;
WASHINGTON
AB We tested the feasibility of transporting steelhead Oncorhynchus mykiss kelts (postspawned adults) around hydroelectric dams on the Snake and Columbia rivers to increase the returns of repeat spawners. Altogether, 5,878 kelts were collected, tagged with passive integrated transponder tags, and assigned to transported or in-river treatment groups at Lower Granite Dam (n = 5,320 [2002-2004]) on the Snake River and John Day Dam (n = 558 [2002]) on the Columbia River. Returns of repeat spawners differed by site and year: 11.1% (62/558) for the John Day Dam sample and 1.4% (27/1,959), 0.5% (6/1,24 1), and 0.8% (17/2,120) for the Lower Granite Darn samples in 2002, 2003, and 2004. respectively. Transportation tests indicated that kelts transported from the Snake River were approximately 2.3 times more likely to return than fish allowed to migrate in-river. Transport benefits were greatest for wild-origin female kelts, a demographic with high conservation value. There was no significant benefit for kelts transported from John Day Dam, although transported fish returned at a slighter higher rate (1.1 times). Comparisons between treatment groups (in-river versus transport) and locations (Snake River versus Columbia River) indicated that the greatest potential transport benefit may be for Snake River kelts owing to the population's low overall iteroparity rate and numerous potential kelt collection sites. The small sample sizes of returning fish limited our ability to examine more complex trends and environmental effects on return rates. Additional research is needed to fully evaluate the efficacy of kelt transportation in the context of regional steelhead recovery efforts.
C1 [Evans, Allen F.; Collis, Ken] Real Time Res Inc, Bend, OR 97702 USA.
[Wertheimer, Robert H.] USA, Corps Engineers, Portland, OR 97208 USA.
[Keefer, Matthew L.; Boggs, Charles T.; Peery, Christopher A.] Univ Idaho, Dept Fish & Wildlife Resources, Idaho Cooperat Fish & Wildlife Res Unit, Moscow, ID 83844 USA.
RP Evans, AF (reprint author), Real Time Res Inc, 52 SW Roosevelt Ave, Bend, OR 97702 USA.
EM aevans@realtimeresearch.org
FU U.S. Army Corps of' Engineers, Walla Walla District
FX This project was funded by the U.S. Army Corps of' Engineers, Walla
Walla District. We thank T. Wik and M. Shutters for their assistance, as
well as M. Halter, J. Harmon, and the staff at Lower Granite Dam, and R.
Cordie, M. Zyndol and the staff at John Day Darn. We are grateful to J.
Dalen, P. Madson, M. Jonas, B. Winans, E. O'Brien, C. Naumann, and J.
Sandquist for their fieldwork, G. Nardacci (Norniandeau Associates) for
project oversight, and R. Beaty (Bonneville Power Administration) for
his innovative ideas regarding this research. Finally, we thank the
staff of the Columbia River Inter-Tribal Fish Commission for their
involvement in this work.
NR 36
TC 9
Z9 9
U1 2
U2 8
PU AMER FISHERIES SOC
PI BETHESDA
PA 5410 GROSVENOR LANE SUITE 110, BETHESDA, MD 20814-2199 USA
SN 0275-5947
J9 N AM J FISH MANAGE
JI North Am. J. Fish Manage.
PD DEC
PY 2008
VL 28
IS 6
BP 1818
EP 1827
DI 10.1577/M08-043.1
PG 10
WC Fisheries
SC Fisheries
GA 477FS
UT WOS:000268504700017
ER
PT J
AU Weichel, ED
Colyer, MH
Ludlow, SE
Bower, KS
Eiseman, AS
AF Weichel, Eric D.
Colyer, Marcus H.
Ludlow, Spencer E.
Bower, Kraig S.
Eiseman, Andrew S.
TI Combat Ocular Trauma Visual Outcomes during Operations Iraqi and
Enduring Freedom
SO OPHTHALMOLOGY
LA English
DT Article
ID OPEN-GLOBE INJURIES; CLASSIFYING MECHANICAL INJURIES; UNITED-STATES; EYE
INJURIES; PROGNOSTIC FACTORS; DESERT-SHIELD; BRAIN-INJURY; WAR;
SURVIVAL; EPIDEMIOLOGY
AB Objective: To report the visual and anatomic outcomes as well as to predict the visual prognosis of combat ocular trauma (COT) during Operations Iraqi and Enduring Freedom.
Design: Retrospective, noncomparative, interventional, consecutive case series.
Participants: Five hundred twenty-three consecutive globe or adnexal combat injuries, or both, sustained by 387 United States soldiers treated at Walter Reed Army Medical Center between March 2003 and October 2006.
Methods: Two hundred one ocular trauma variables were collected on each injured soldier. Best-corrected visual acuity (BCVA) was categorized using the ocular trauma score (OTS) grading system and was analyzed by comparing initial and 6-month postinjury BCVA.
Main Outcome Measures: Best-corrected visual acuity, OTS, and globe, oculoplastic, neuro-ophthalmic, and associated nonocular injuries.
Results: The median age was 25 7 years (range, 18-57 years), with the median baseline OTS of 70 25 (range, 12-100). The types of COT included closed-globe (n = 234; zone 1+2, n = 103; zone 3, n = 131), open-globe (n = 198; intraocular foreign body, n = 86; perforating, n = 61; penetrating, n = 32; and rupture, n = 19), oculoplastic (n = 324), and neuro-ophthalmic (n = 135) injuries. Globe trauma was present in 432 eyes, with 253 eyes used for visual acuity analysis. Comparing initial versus 6-month BCVA, 42% of eyes achieved a BCVA of 20/40 or better, whereas 32% of eyes had a BCVA of no light perception. Closed-globe injuries accounted for 65% of BCVA of 20/40 or better, whereas 75% of open-globe injuries had a BCVA of 20/200 or worse. The ocular injuries with the worst visual outcomes included choroidal hemorrhage, globe perforation or rupture, retinal detachment, submacular hemorrhage, and traumatic optic neuropathy. Additionally, COT that combined globe injury with oculoplastic or neuro-ophthalmologic injury resulted in the highest risk of final BCVA worse than 20/200 (odds ratio, 11.8; 95% confidence interval, 4.0-34.7; P<0.0005). Nonocular injuries occurred in 85% of cases and included traumatic brain injury (66%) and facial injury (58%). Extremity injuries were 44% (170 of 387 soldiers). Amputation is a subset of extremity injury with 12% (46 of 387) having sustained a severe extremity injury causing amputation.
Conclusions: Combat ocular trauma has high rates of nonocular injuries with better visual outcomes in closed-globe compared with open-globe trauma. The OTS is a valid classification scheme for COT and correlates the severity of injury with the final visual acuity and prognosis. Globe combined with oculoplastic or neuro-ophthalmologic injuries have the worst visual prognosis.
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. Ophthalmology 2008;115:2235-2245 (C) 2008 by the American Academy of Ophthalmology.
C1 [Weichel, Eric D.] Walter Reed Army Med Ctr, Ophthalmol Serv, Washington, DC 20307 USA.
RP Weichel, ED (reprint author), Walter Reed Army Med Ctr, Ophthalmol Serv, 6900 Georgia Ave, Washington, DC 20307 USA.
EM eweichel@hotmail.com
NR 68
TC 68
Z9 74
U1 2
U2 5
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0161-6420
J9 OPHTHALMOLOGY
JI Ophthalmology
PD DEC
PY 2008
VL 115
IS 12
BP 2235
EP 2245
DI 10.1016/j.ophtha.2009.08.033
PG 11
WC Ophthalmology
SC Ophthalmology
GA 381PK
UT WOS:000261548200017
PM 19041478
ER
PT J
AU Merkle, LD
Newburgh, GA
Ter-Gabrielyan, N
Michael, A
Dubinskii, M
AF Merkle, Larry D.
Newburgh, G. Alex
Ter-Gabrielyan, Nikolay
Michael, Arockiasamy
Dubinskii, Mark
TI Temperature-dependent lasing and spectroscopy of Yb:Y(2)O(3) and
Yb:Sc(2)O(3)
SO OPTICS COMMUNICATIONS
LA English
DT Article
DE Laser materials; Condensed matter spectroscopy
ID YB-Y2O3 CERAMIC LASER; ND-YAG; YB-YAG; SESQUIOXIDES; YB3+-SC2O3;
OPERATION; EMISSION; CRYSTALS
AB Spectroscopic and laser properties of Yb(3+) in ceramic Y(2)O(3) have been studied at room and cryogenic temperatures. Laser performance is very substantially improved by cooling to liquid nitrogen temperature, primarily due to the great reduction in ground state absorption that permits laser operation on the much stronger 1030-nm emission line rather than the 1077-nm line. The 976-nm "zero line" is observed to become much weaker as the temperature is reduced. Several models for this behavior are considered, but none adequately explains this surprising result. Spectroscopy of Yb:Sc(2)O(3) indicates that it is likely to be an even better cryogenic gain material, given samples of comparable optical quality. (C) 2008 Elsevier B.V. All rights reserved.
C1 [Merkle, Larry D.; Newburgh, G. Alex; Ter-Gabrielyan, Nikolay; Michael, Arockiasamy; Dubinskii, Mark] Attn AMSRD ARL SE EO, Army Res Lab, Adelphi, MD 20783 USA.
RP Merkle, LD (reprint author), Attn AMSRD ARL SE EO, Army Res Lab, 2800 Powder Mill Rd, Adelphi, MD 20783 USA.
EM larry.d.merkle@us.army.mil
FU High Energy Lasers Joint Technology Office
FX The authors wish to thank Thomas Backes for his careful contributions to
the early spectroscopic phases of this study, and to gratefully
acknowledge financial support from the High Energy Lasers Joint
Technology Office.
NR 20
TC 17
Z9 17
U1 4
U2 14
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0030-4018
J9 OPT COMMUN
JI Opt. Commun.
PD DEC 1
PY 2008
VL 281
IS 23
BP 5855
EP 5861
DI 10.1016/j.optcom.2008.08.043
PG 7
WC Optics
SC Optics
GA 378AS
UT WOS:000261294100039
ER
PT J
AU Gentlesk, PJ
Sauer, WH
Peele, ME
Eckart, RE
AF Gentlesk, Philip J.
Sauer, William H.
Peele, Mark E.
Eckart, Robert E.
TI Spontaneous Premature Atrial Depolarization Proving the Mechanism of a
Wide Complex Tachycardia
SO PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
LA English
DT Article
DE catheter ablation; WPW; AVRT; cardiac mapping; electrogram analysis
ID MAHAIM FIBER
C1 [Gentlesk, Philip J.] Brooke Army Med Ctr, Div Cardiol MCHE MDC, Ft Sam Houston, TX 78234 USA.
[Sauer, William H.] Univ Colorado Hosp, Denver, CO USA.
RP Gentlesk, PJ (reprint author), Brooke Army Med Ctr, Div Cardiol MCHE MDC, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA.
EM Philip.Gentlesk@amedd.army.mil
NR 4
TC 2
Z9 2
U1 0
U2 0
PU BLACKWELL PUBLISHING
PI OXFORD
PA 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND
SN 0147-8389
J9 PACE
JI PACE-Pacing Clin. Electrophysiol.
PD DEC
PY 2008
VL 31
IS 12
BP 1625
EP 1627
DI 10.1111/j.1540-8159.2008.01236.x
PG 3
WC Cardiac & Cardiovascular Systems; Engineering, Biomedical
SC Cardiovascular System & Cardiology; Engineering
GA 374YJ
UT WOS:000261079300016
PM 19067817
ER
PT J
AU McAdams, RM
Ellis, MW
Trevino, S
Rajnik, M
AF McAdams, Ryan M.
Ellis, Michael W.
Trevino, Sherry
Rajnik, Michael
TI Spread of methicillin-resistant Staphylococcus aureus USA300 in a
neonatal intensive care unit
SO PEDIATRICS INTERNATIONAL
LA English
DT Article
DE infant; infection control; methicillin-resistant Staphylococcus aureus;
USA300
ID FIELD GEL-ELECTROPHORESIS; PANTON-VALENTINE LEUKOCIDIN; NOSOCOMIAL
TRANSMISSION; INFECTION; CHILDREN; EMERGENCE; STRAINS; COLONIZATION;
SURVEILLANCE; HOUSEHOLDS
AB Reports of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in neonatal intensive care units (NICU) and in otherwise healthy patients without obvious risk factors have been increasing in frequency. Described herein is a cluster of cases of CA-MRSA USA300 strains in an NICU affecting infants, health-care workers and the health-care workers' families.
Infants and health-care workers with infection and colonization due to MRSA between 1 January 2004 and 30 June 2005 in a tertiary care center NICU in San Antonio, TX were studied. Antimicrobial susceptibility testing and polymerase chain reaction detection of the mecA gene characterized the MRSA isolates. All MRSA cases were reviewed for clinical severity of infection and outcome.
During the 18 months studied, a total of four (0.6%) of 676 infants had CA-MRSA bacteremia or colonization. One infant with necrotizing pneumonia died and three health-care workers who directly cared for the infected infants developed soft-tissue infections caused by CA-MRSA. Four family members of two health-care workers subsequently developed soft-tissue infections. All of the analyzed isolates (eight of nine) belonged to pulsed-field type USA300 and possessed Panton-Valentine leukocidin genes, which have been associated with severe skin and soft-tissue infections, and necrotizing pneumonia.
It is likely that the CA-MRSA USA300 strain can be transmitted between NICU patients to health-care workers and their family members. The CA-MRSA cases reported here reinforce the virulence of CA-MRSA USA300 strains and emphasize the need to embrace infection control practices designed to protect hospitalized patients, health-care workers and their family members.
C1 [McAdams, Ryan M.] US Naval Hosp Okinawa, Dept Neonatol, Fpo, AP 963621600, Japan.
[McAdams, Ryan M.] 18th Med Grp, Kadena Air Base, Japan.
[McAdams, Ryan M.; Rajnik, Michael] Wilford Hall USAF Med Ctr, Dept Pediat, San Antonio, TX 78236 USA.
[Trevino, Sherry] Wilford Hall USAF Med Ctr, Dept Pathol, San Antonio, TX 78236 USA.
[Ellis, Michael W.] Brooke Army Med Ctr, Dept Infect Dis, San Antonio, TX USA.
[Rajnik, Michael] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
RP McAdams, RM (reprint author), US Naval Hosp Okinawa, Dept Neonatol, PSC 482, Fpo, AP 963621600, Japan.
EM ryan.mcadams@.med.navy.mil
NR 48
TC 22
Z9 24
U1 1
U2 2
PU WILEY-BLACKWELL PUBLISHING, INC
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1328-8067
J9 PEDIATR INT
JI Pediatr. Int.
PD DEC
PY 2008
VL 50
IS 6
BP 810
EP 815
DI 10.1111/j.1442-200X.2008.02646.x
PG 6
WC Pediatrics
SC Pediatrics
GA 374YU
UT WOS:000261080400004
PM 19067897
ER
PT J
AU Schnall, BL
Baum, BS
Andrews, AM
AF Schnall, Barri L.
Baum, Brian S.
Andrews, Anne M.
TI Gait Characteristics of a Soldier With a Traumatic Hip Disarticulation
SO PHYSICAL THERAPY
LA English
DT Article
ID ENERGY-EXPENDITURE; KNEE STABILITY; AMPUTEES; AMPUTATION; WALKING; SPEED
AB Background and Purpose. No reports have analyzed the temporal-spatial, kinematic, or kinetic components of gait coupled with a metabolic analysis of patients with hip disarticulations. Most of the research on this population is based on older adults. As a result, guidelines for reasonable functional outcomes for patients with hip disarticulations who are Young, premorbidly fit, and goal oriented are lacking. This report describes quantitative measures of energy cost and gait characteristics of a young soldier with a unilateral traumatic hip disarticulation.
Case Description. One patient, a soldier with a unilateral hip disarticulation, was evaluated in the Gait and Motion Analysis Laboratory at 3 months and 38 months postinjury.
Outcomes. The patient progressed from use of crutches at 3 months postinjury to independent ambulation at the follow-up visit at 38 months postinjury. At 38 months postinjury, lie wore his prosthesis 12 hours per day and achieved step-length symmetry, and his oxygen consumption was 14.49 mL/kg/min at self-selected walking speed. Self-selected walking speed increased from 0.57 m/s at 3 months to 0.86 m/s at 38 months postinjury. During both visits, support time remained greater on the intact limb (72%) than the involved limb (57%), compensator), trunk and pelvic motions were used to advance the prosthetic limb, and the vertical ground reaction force profile was within 2 standard deviations of the data for an uninjured comparison group on the prosthetic side and plateaued on the sound limb.
Discussion. Young individuals with traumatic hip disarticulations can achieve and maintain functional independent ambulation with gait deviations. However, metabolic demands may not be as great as previously expected.
C1 [Schnall, Barri L.; Baum, Brian S.] Walter Reed Army Med Ctr, Mil Adv Training Ctr, Ctr Performance & Clin Res, Washington, DC 20307 USA.
[Andrews, Anne M.] Walter Reed Army Med Ctr, Nutr Care Directorate, Div Res & Educ, Washington, DC USA.
RP Schnall, BL (reprint author), Walter Reed Army Med Ctr, Mil Adv Training Ctr, Ctr Performance & Clin Res, Bldg 2A,Room 146,6900 Georgia Ave NW, Washington, DC 20307 USA.
EM barri.schnall@na.amedd.army.mil
RI Baum, Brian/K-2737-2012
OI Baum, Brian/0000-0003-0692-1962
FU Military Amputee Research Program
FX The authors thank the Military Amputee Research Program for support of
this project.
NR 20
TC 6
Z9 7
U1 0
U2 3
PU AMER PHYSICAL THERAPY ASSOC
PI ALEXANDRIA
PA 1111 N FAIRFAX ST, ALEXANDRIA, VA 22314 USA
SN 0031-9023
J9 PHYS THER
JI Phys. Ther.
PD DEC
PY 2008
VL 88
IS 12
BP 1568
EP 1577
DI 10.2522/ptj.20070337
PG 10
WC Orthopedics; Rehabilitation
SC Orthopedics; Rehabilitation
GA 381PU
UT WOS:000261549200015
PM 18849481
ER
PT J
AU Buller, MJ
Latzka, WA
Yokota, M
Tharion, WJ
Moran, DS
AF Buller, Mark J.
Latzka, William A.
Yokota, Miyo
Tharion, William J.
Moran, Daniel S.
TI A real-time heat strain risk classifier using heart rate and skin
temperature
SO PHYSIOLOGICAL MEASUREMENT
LA English
DT Article
DE heat strain classification; real-time physiological monitoring;
physiological strain index; heart rate and skin temperature; risk-based
classification
ID EXERCISE; STRESS; HYPERHYDRATION; RESPONSES; TOLERANCE; WOMEN
AB Heat injury is a real concern to workers engaged in physically demanding tasks in high heat strain environments. Several real-time physiological monitoring systems exist that can provide indices of heat strain, e. g. physiological strain index ( PSI), and provide alerts to medical personnel. However, these systems depend on core temperature measurement using expensive, ingestible thermometer pills. Seeking a better solution, we suggest the use of a model which can identify the probability that individuals are 'at risk' from heat injury using non-invasive measures. The intent is for the system to identify individuals who need monitoring more closely or who should apply heat strain mitigation strategies. We generated a model that can identify 'at risk' (PSI >= 7.5) workers from measures of heart rate and chest skin temperature. The model was built using data from six previously published exercise studies in which some subjects wore chemical protective equipment. The model has an overall classification error rate of 10% with one false negative error (2.7%), and outperforms an earlier model and a least squares regression model with classification errors of 21% and 14%, respectively. Additionally, the model allows the classification criteria to be adjusted based on the task and acceptable level of risk. We conclude that the model could be a valuable part of a multifaceted heat strain management system.
C1 [Buller, Mark J.; Latzka, William A.; Yokota, Miyo; Tharion, William J.] USA, Environm Med Res Inst, Natick, MA 01760 USA.
[Moran, Daniel S.] Chaim Sheba Med Ctr, Heller Inst Med Res, Inst Mil Physiol, IL-52621 Tel Hashomer, Israel.
RP Buller, MJ (reprint author), USA, Environm Med Res Inst, Natick, MA 01760 USA.
EM mark.j.buller@us.army.mil
NR 21
TC 9
Z9 10
U1 1
U2 9
PU IOP PUBLISHING LTD
PI BRISTOL
PA DIRAC HOUSE, TEMPLE BACK, BRISTOL BS1 6BE, ENGLAND
SN 0967-3334
J9 PHYSIOL MEAS
JI Physiol. Meas.
PD DEC
PY 2008
VL 29
IS 12
BP N79
EP N85
DI 10.1088/0967-3334/29/12/N01
PG 7
WC Biophysics; Engineering, Biomedical; Physiology
SC Biophysics; Engineering; Physiology
GA 377OK
UT WOS:000261260300008
PM 18946156
ER
PT J
AU Reddy, AS
Kalyani, S
Kumar, NS
Boddu, VM
Krishnaiah, A
AF Reddy, A. Subba
Kalyani, S.
Kumar, N. Siva
Boddu, Veera M.
Krishnaiah, A.
TI Dehydration of 1,4-dioxane by pervaporation using crosslinked calcium
alginate-chitosan blend membranes
SO POLYMER BULLETIN
LA English
DT Article
ID ACETIC ACID MIXTURES; SODIUM ALGINATE; COMPOSITE MEMBRANES; POLY(VINYL
ALCOHOL); DIOXANE MIXTURES; AQUEOUS MIXTURES; SEPARATION; WATER;
ISOPROPANOL; PERFORMANCE
AB Sodium alginate (SA) and chitosan (CS) blended membranes were crosslinked with maleic anhydride (MA) for the separation of 1,4-dioxane/water mixtures at 30 degrees C by pervaporation (PV). The membranes were characterized by Fourier transform infrared (FTIR) analysis and Ion Exchange Capacity (IEC) to verify the crosslinking. Thermogravimetric analysis (TGA) and X-ray diffraction (XRD) pattern were used to observe the thermal degradation and crystalline nature of the membrane respectively. The membrane performance was studied by calculating flux, selectivity, and pervaporation separation index. Sorption studies were carried out to evaluate the extent of interaction and degree of swelling of the membranes in pure liquids as well as in binary mixtures. The effects of experimental parameters such as feed composition, membrane thickness, and permeate pressure on separation performance of the crosslinked membranes were determined. The experimental result suggested that the membrane has a good potential for breaking the aqueous azeotrope 1,4-dioxane.
C1 [Reddy, A. Subba; Kalyani, S.; Kumar, N. Siva; Krishnaiah, A.] Sri Venkateswara Univ, Dept Chem, Biopolymers & Thermophys Labs, Tirupati 517502, Andhra Pradesh, India.
[Boddu, Veera M.] USA, Erdc, Construct Engn Res Lab, Champaign, IL 61822 USA.
RP Krishnaiah, A (reprint author), Sri Venkateswara Univ, Dept Chem, Biopolymers & Thermophys Labs, Tirupati 517502, Andhra Pradesh, India.
EM abburikrishnaiah@gmail.com
RI Dr., Nadavala Siva Kumar /D-5404-2011; swayampakula, kalyani/D-6233-2011
OI Dr., Nadavala Siva Kumar /0000-0003-3210-8254;
FU Council of Scientific and Industrial Research (CSIR), New Delhi
FX The authors are thankful to the Council of Scientific and Industrial
Research (CSIR), New Delhi for financial support.
NR 24
TC 14
Z9 14
U1 1
U2 17
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0170-0839
J9 POLYM BULL
JI Polym. Bull.
PD DEC
PY 2008
VL 61
IS 6
BP 779
EP 790
DI 10.1007/s00289-008-1003-x
PG 12
WC Polymer Science
SC Polymer Science
GA 382BL
UT WOS:000261579700012
ER
PT J
AU Qiu, JJ
Li, J
Zhang, C
Liang, R
Lin, SS
Wang, B
Walsh, S
AF Qiu, Jingjing
Li, Jing
Zhang, Chuck
Liang, Richard
Lin, Shui-Shun
Wang, Ben
Walsh, Shawn
TI Influence of Alcohol Pre-Infusion on the Quality of VARTM Composites
SO POLYMER COMPOSITES
LA English
DT Article
ID TRANSFER MOLDING PROCESS/; FLOW; SIMULATION; MODEL; RTM
AB In the vacuum assisted resin transfer molding (VARTM) process, part-to-part variations such as the uncertainty in the permeability and race tracking phenomenon make it difficult to achieve consistent mold filling and ensure part quality of composites. Alcohol pre-infusion was presented in this study as a novel real-time monitoring and control approach for the flow process in the VARTM process, alcohol test fluid is infused before the actual resin infusion to locate the potential dry spots without using the large quantity of sensors. Then corresponding process control strategy is designed, such as opening the auxiliary gate at specific moment on those predicted dry spot locations to compensate flow defects. Moreover, alcohol can be easily removed by heat without changing the local permeability. The influence of alcohol pre-infusion on the quality of VARTM composites were investigated in this study. The mechanical tests were conducted to verify that the alcohol pre-infusion approach has no significant effect on composite properties because alcohol can be removed from fiber by heat and air flow. Specifically, DMA, TGA, and FTIR spectrum proved that negligible difference existed on the resin-fiber interface between the composites with or without alcohol pre-infusion. Finally, the microscopy results revealed a similar failure path in a resin matrix. TMA results also demonstrated similar dimension stability. This alcohol pre-infusion approach was effective when compared with computer simulation and could eliminate the occurrence of dry spots and voids without using sensors or data-acquisition system. The control schemes were shown in a case study to be capable of compensating the flow defects and achieving desired fill patterns in the face of permeability uncertainty. POLYM. COMPOS., 29:1310-1320, 2008. (C) 2008 Society of Plastics Engineers
C1 [Qiu, Jingjing; Li, Jing; Zhang, Chuck; Liang, Richard; Lin, Shui-Shun; Wang, Ben] Florida State Univ, Florida A&M Univ, High Performance Mat Inst, Dept Ind & Mfg Engn,Coll Engn, Tallahassee, FL 32310 USA.
[Walsh, Shawn] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Zhang, C (reprint author), Florida State Univ, Florida A&M Univ, High Performance Mat Inst, Dept Ind & Mfg Engn,Coll Engn, Tallahassee, FL 32310 USA.
EM chzhang@eng.fsu.edu
RI Qiu, Jingjing/E-9248-2015
OI Qiu, Jingjing/0000-0001-9643-5452
FU Army Research Laboratory; Office of Naval Research; Siemens Power
Generation; National Science Foundation [0224612]
FX This research work has been supported by Army Research Laboratory,
Office of Naval Research, Siemens Power Generation, and National Science
Foundation I/UCRC Program (Award #: 0224612).
NR 17
TC 0
Z9 0
U1 1
U2 10
PU JOHN WILEY & SONS INC
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN, NJ 07030 USA
SN 0272-8397
J9 POLYM COMPOSITE
JI Polym. Compos.
PD DEC
PY 2008
VL 29
IS 12
BP 1310
EP 1320
DI 10.1002/pc.20514
PG 11
WC Materials Science, Composites; Polymer Science
SC Materials Science; Polymer Science
GA 377BV
UT WOS:000261227600005
ER
PT J
AU Calvano, TP
Sill, JM
Kemp, KR
Chung, KK
AF Calvano, Tatjana P.
Sill, Joshua M.
Kemp, Kenneth R.
Chung, Kevin K.
TI Use of a High-Flow Oxygen Delivery System in a Critically Ill Patient
With Dementia
SO RESPIRATORY CARE
LA English
DT Article
DE high-flow oxygen; palliative care; hypoxemia
ID CARE-ASSOCIATED PNEUMONIA; OBSTRUCTIVE PULMONARY-DISEASE;
COMMUNITY-ACQUIRED PNEUMONIA; NASAL CANNULA; INDUCED ASTHMA; EXERCISE;
EPIDEMIOLOGY; VENTILATION; OUTCOMES; O2
AB We used a high-flow nasal cannula with a patient who required a high fraction of inspired oxygen but could not tolerate a nasal or facial mask. We saw a 92-year-old woman with delirium and dementia in the intensive care unit for multi-lobar pneumonia with severe hypoxemia. Attempts to oxygenate the patient failed because she was unable to tolerate various facial and nasal masks. We then tried a high-flow nasal cannula (Vapotherm 2000i), which she tolerated well, and she had marked improvement in gas exchange and quality of life. The patient had severe health-care-associated pneumonia, accompanied by delirium and hypoxemia. It became apparent that the patient's death was imminent, and the goal of therapy was palliative. She had previously clearly expressed a desire not to undergo intubation and mechanical ventilation. In a situation where the patient was agitated and unable to tolerate a mask, the high-flow cannula reduced her agitation and improved her dyspnea, oxygenation, tolerance of oxygen therapy, and comfort at the end of life. Oxygen via high-flow cannula may enhance quality of life by reducing hypoxemia in patients who are unable to tolerate a mask but need a high oxygen concentration.
C1 [Calvano, Tatjana P.] Brooke Army Med Ctr, Dept Internal Med, Ft Sam Houston, TX 78234 USA.
[Sill, Joshua M.; Kemp, Kenneth R.] Brooke Army Med Ctr, Dept Pulm Med, Ft Sam Houston, TX 78234 USA.
[Chung, Kevin K.] Brooke Army Med Ctr, Burn Ctr, Ft Sam Houston, TX 78234 USA.
RP Calvano, TP (reprint author), Brooke Army Med Ctr, Dept Internal Med, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA.
EM tatjana.calvano@amedd.army.mil
NR 28
TC 11
Z9 11
U1 2
U2 2
PU DAEDALUS ENTERPRISES INC
PI IRVING
PA 9425 N MAC ARTHUR BLVD, STE 100, IRVING, TX 75063-4706 USA
SN 0020-1324
J9 RESP CARE
JI Respir. Care
PD DEC
PY 2008
VL 53
IS 12
BP 1739
EP 1743
PG 5
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA 381BZ
UT WOS:000261511100017
PM 19025711
ER
PT J
AU Rosenstein, JE
AF Rosenstein, Judith E.
TI Individual threat, group threat, and racial policy: Exploring the
relationship between threat and racial attitudes
SO SOCIAL SCIENCE RESEARCH
LA English
DT Article; Proceedings Paper
CT 101st Annual Meeting of the American-Sociological-Association
CY AUG 11-14, 2006
CL Montreal, CANADA
SP Amer Sociol Assoc
DE racial threat; prejudice; racial attitudes
ID PUBLIC-OPINION; SYMBOLIC RACISM; GROUP POSITION; AFFIRMATIVE-ACTION;
PERCEIVED THREAT; WESTERN-EUROPE; UNITED-STATES; LABOR-MARKET;
PREJUDICE; SOUTH
AB Racial threat scholars have long argued that racial prejudice is motivated by threat. This literature identifies two types of threat: individual threat and group threat; however, actual arguments tend to focus on only one of the two types of threat. Consequently, there has been no assessment of whether both threats are simultaneously associated with prejudice. This paper uses data from the 1994 General Social Survey (GSS) to examine the relationship between perceptions of individual threat, perceptions of group threat, and opposition to policies aiding blacks. Results from multinomial logits demonstrate that both threats are associated with opposition to race-equalizing policies, suggesting that single-threat theories should be reevaluated and that studies incorporating racial threat should include both types of threat. (c) 2008 Elsevier Inc. All rights reserved.
C1 US Mil Acad, Dept Behav Sci & Leadership, West Point, NY 10996 USA.
RP Rosenstein, JE (reprint author), US Mil Acad, Dept Behav Sci & Leadership, 601 Cullum Rd, West Point, NY 10996 USA.
EM jer33@cornell.edu
NR 59
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Z9 15
U1 1
U2 15
PU ACADEMIC PRESS INC ELSEVIER SCIENCE
PI SAN DIEGO
PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA
SN 0049-089X
J9 SOC SCI RES
JI Soc. Sci. Res.
PD DEC
PY 2008
VL 37
IS 4
BP 1130
EP 1146
DI 10.1016/j.ssresearch.2008.04.001
PG 17
WC Sociology
SC Sociology
GA 355BY
UT WOS:000259685100006
PM 19227695
ER
PT J
AU Grujicic, M
Pandurangan, B
Courtis, N
Cheeseman, BA
Roy, WN
Skaggs, RR
AF Grujicic, M.
Pandurangan, B.
Courtis, N.
Cheeseman, B. A.
Roy, W. N.
Skaggs, R. R.
TI Computer-simulations based development of a high strain-rate,
large-deformation, high-pressure material model for STANAG 4569 sandy
gravel
SO SOIL DYNAMICS AND EARTHQUAKE ENGINEERING
LA English
DT Article
DE Sandy gravel; Material model; STANAG 4569
ID STRENGTH; SOILS
AB The NATO Standard Agreement [STANAG 4569, Protection for occupants of logistics and light-armored vehicles] defines the make-up and the conditions of sandy-gravel soil which is used for testing the ability of various armor systems to provide the necessary level of protection. In this paper. all effort is made to develop it high strain-rate, large-strain, high-pressure material model for sandy gravel which can be used in transient non-linear dynamic simulations of the interactions between landmine detonation gaseous products. landmine-casing fragments and soil ejecta and the target military vehicles. The material model for sandy gravel has been developed by extending the CU-ARL sand model [Grujicic M, Pandurangan B, Cheeseman BA, Roy WN, Skaggs RR, Gupta R. Parameterization of the porous-material model for sand with various degrees of water Saturation. Soil Dyn Earthquake Eng 2008,28(1):20-35] in order to include the effects of gravel particles on the equation of state. strength. failure and erosion behavior. Parametrization of the sandy gravel soil model has been done by carrying out a series of computational experiments pertaining to the deformation and fracture behavior of the two-phase (sand plus gravel) material. Experimental tests which should be carried out in order to validate the proposed model have been identified and described. (C) 2007 Elsevier Ltd. All rights reserved.
C1 [Grujicic, M.; Pandurangan, B.; Courtis, N.] Clemson Univ, Dept Mech Engn, Clemson, SC 29634 USA.
[Cheeseman, B. A.; Roy, W. N.; Skaggs, R. R.] USA, Res Lab, Survivabil Mat Branch, Aberdeen Proving Ground, MD 21005 USA.
RP Grujicic, M (reprint author), Clemson Univ, Dept Mech Engn, Clemson, SC 29634 USA.
EM mica.grujicic@ces.clemson.edu
FU US Army/Clemson University Cooperative Agreements [W91 1NF-04-2-0024,
W91 1NF-06-20042]; US Army [DAAD19-01-10661]
FX The material presented in this paper is based on work supported by the
US Army/Clemson University Cooperative Agreements W91 1NF-04-2-0024 and
W91 1NF-06-20042 and by the US Army Grant number DAAD19-01-10661. The
authors are indebted to Dr. Fred Stanton for the support and a
continuing interest in the present work.
NR 27
TC 13
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U1 0
U2 5
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0267-7261
J9 SOIL DYN EARTHQ ENG
JI Soil Dyn. Earthq. Eng.
PD DEC
PY 2008
VL 28
IS 12
BP 1045
EP 1062
DI 10.1016/j.soildyn.2007.11.008
PG 18
WC Engineering, Geological; Geosciences, Multidisciplinary
SC Engineering; Geology
GA 373XP
UT WOS:000261007100009
ER
PT J
AU Nelson, JD
Richard, RL
Barillo, DJ
Quick, CD
Hedman, TL
Wolf, S
AF Nelson, Joy D.
Richard, Reginald L.
Barillo, David J.
Quick, Charles D.
Hedman, Travis L.
Wolf, Steven
TI Regaining Function, Improving Life
SO SOUTHERN MEDICAL JOURNAL
LA English
DT Meeting Abstract
C1 [Nelson, Joy D.; Richard, Reginald L.; Barillo, David J.; Quick, Charles D.; Hedman, Travis L.; Wolf, Steven] USA, Inst Surg Res, Ft Sam Houston, TX 78234 USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0038-4348
J9 SOUTH MED J
JI South.Med.J.
PD DEC
PY 2008
VL 101
IS 12
BP S30
EP S30
PG 1
WC Medicine, General & Internal
SC General & Internal Medicine
GA 384XT
UT WOS:000261778200032
ER
PT J
AU Ashman, CR
Pennington, G
AF Ashman, Christopher R.
Pennington, Gary
TI Nitrogen adsorption phases on the 4H-SiC(0001) Si-face
SO SURFACE SCIENCE
LA English
DT Article
DE Density functional calculations; Chemisorption; Growth; Interface
states; Surface structure; SiC; Nitrogen
ID 4H-SIC/SIO2 INTERFACE; CONDUCTION-BAND; SURFACES; DENSITY; PASSIVATION;
OXYNITRIDES; GENERATION; OXIDATION; STATES; LAYERS
AB Using the density functional theory this paper identifies two phases of nitrogen which form on the 4H-SiC(0001) Si-face. At 1/3 ML, N-adatoms occupy the sites between three surface silicon atoms bonding to each of the three available half-filled silicon dangling bonds. This passivates the surface dangling bonds and removes states from the upper half of the band gap. Above this coverage nitrogen atoms pair on the surface to form dimers with a corresponding. change in the chemical potential. The nitrogen dimers reintroduce states into the SiC band gap. Between 1/3 ML and 1 ML coverage, the nitrogen redistributes in patches corresponding to regions of 1/3 ML coverage and 1 ML coverage. At 1 ML the nitrogen dimers populate all the silicon dangling bonds, thus forming a new surface phase. Above 1 ML a third bonding configuration appears in which the nitrogen dimers are only a singly bonded to the surface. This configuration saturates at 2 ML. (C) 2008 Elsevier B.V. All rights reserved.
C1 [Ashman, Christopher R.] High Performance Technol Inc, Reston, VA 20190 USA.
[Pennington, Gary] USA, Res Lab, Adelphi, MD 20783 USA.
RP Ashman, CR (reprint author), High Performance Technol Inc, 11955 Freedom Dr,Suite 1100, Reston, VA 20190 USA.
EM ashman@nrl.navy.mil
FU Department-of Defense High performance Computing Modernization Office
FX Simulations were performed on computers at the Army Research Laboratory
with the assistance of the PET program of the Department-of Defense High
performance Computing Modernization Office. We thank those institutions
for their valuable support.
NR 31
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U1 0
U2 4
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0039-6028
EI 1879-2758
J9 SURF SCI
JI Surf. Sci.
PD DEC 1
PY 2008
VL 602
IS 23
BP 3617
EP 3622
DI 10.1016/j.susc.2008.10.013
PG 6
WC Chemistry, Physical; Physics, Condensed Matter
SC Chemistry; Physics
GA 383UK
UT WOS:000261699000010
ER
PT J
AU Kim, SH
Nam, MH
Roh, KH
Park, HC
Nam, DH
Park, GH
Han, ET
Klein, TA
Lim, CS
AF Kim, Sun Hyung
Nam, Myung-Hyun
Roh, Kyoung Ho
Park, Hae Chul
Nam, Deok Hwa
Park, Gli Hong
Han, Eun Taek
Klein, Terry A.
Lim, Chae Seung
TI Evaluation of a rapid diagnostic test specific for Plasmodium vivax
SO TROPICAL MEDICINE & INTERNATIONAL HEALTH
LA English
DT Article
DE Plasmodium vivax; OptiMAL; parasite lactate dehydrogenase; SD Malaria
Antigen P; v
ID SUSPECTED MALARIA PATIENTS; ANTIGEN-CAPTURE ASSAY; FALCIPARUM-MALARIA;
EXPERT MICROSCOPY; GENETIC DIVERSITY; PERFORMANCE
AB Plasmodium vivax is the only human malaria indigenous to the Republic of Korea (ROK). A rapid and sensitive diagnostic test (RDT) that detects P. vivax is appropriate for evaluating suspected malaria patients with no travel history abroad. The RDTs, SD Malaria Antigen P.v (SD diagnostic, Kyonggi, ROK) specific for P. vivax and the well documented OptiMAL (DiaMed, Cressier, Switzerland) were compared among 282 volunteers for specificity and sensitivity of P. vivax and Plasmodium falciparum malaria infections against Giemsa-stained blood smears read by an experienced microscopist. A total of 137 volunteers were diagnosed with P. vivax, 45 cases (returned travellers from overseas) were diagnosed with P. falciparum and 100 healthy volunteers were diagnosed as negative for malaria. Correspondingly, the SD Malaria Antigen P.v test identified P. vivax infections in 128/137 malaria patients (93.4%) and 0/100 (0%) healthy volunteers. Three patients identified with P. falciparum also were interpreted as P. vivax by the SD Malaria Antigen P.v test; however, these patients were later confirmed as mixed infections of P. vivax and P. falciparum by polymerase chain reaction. OptiMAL interpreted the three mixed infections only as P. falciparum and detected 130/137 (94.9%) patients with P. vivax. The sensitivity of the SD Malaria Antigen P.v test decreased from 100% (> 5000 parasite/mu l) to 81.3% (1-100 parasites/mu l) as parasitaemia levels declined. For the regions where P. vivax is the primary malaria parasite, the SD P. vivax-specific rapid diagnostic test may be useful for screening suspected malaria patients when sufficient material and human resources (e.g. trained microscopists) are unavailable for malaria diagnosis.
C1 [Kim, Sun Hyung; Nam, Myung-Hyun; Roh, Kyoung Ho; Nam, Deok Hwa; Lim, Chae Seung] Korea Univ, Coll Med, Dept Lab Med, Seoul 136705, South Korea.
[Roh, Kyoung Ho] Konyang Univ, Coll Med, Dept Lab Med, Taejon, South Korea.
[Park, Hae Chul] Korea Univ, Coll Med, Neurophysiol Lab, Seoul 136705, South Korea.
[Park, Gli Hong] Korea Univ, Coll Med, Dept Biochem, Seoul 136705, South Korea.
[Han, Eun Taek] Kangwon Univ, Coll Med, Dept Parasitol, Chunchon, Kangwon Prov, South Korea.
[Klein, Terry A.] US Army, Med Command 18, Seoul, South Korea.
RP Lim, CS (reprint author), Korea Univ, Ansan Hosp, Coll Med, Dept Lab Med, 516 Gojan Dong, Ansan 425707, Gyeonggi Prov, South Korea.
EM malarim@korea.ac.kr
FU Korea University Medical Center; Seoul R BD program
FX The authors would like to thank Dr Dae Won Park and In Keun Choi at the
Korea university Ansan hospital. The authors are grateful for the
cooperation of the non-malaria and malaria patients who volunteered for
this study. This work was supported by the U-health program of the Korea
University Medical Center, Seoul R & BD program (2007). SD Malaria
Antigen P. v and SD Malaria Antigen P.f kits were donated for evaluation
by SD Diagnostic Corporation.
NR 26
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U1 1
U2 2
PU WILEY-BLACKWELL
PI MALDEN
PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
SN 1360-2276
J9 TROP MED INT HEALTH
JI Trop. Med. Int. Health
PD DEC
PY 2008
VL 13
IS 12
BP 1495
EP 1500
DI 10.1111/j.1365-3156.2008.02163.x
PG 6
WC Public, Environmental & Occupational Health; Tropical Medicine
SC Public, Environmental & Occupational Health; Tropical Medicine
GA 376UW
UT WOS:000261209500010
PM 18983278
ER
PT J
AU Le Fer, D
Fraser, JD
Kruse, CD
AF Le Fer, Danielle
Fraser, James D.
Kruse, Casey D.
TI Piping Plover Foraging-Site Selection on the Missouri River
SO WATERBIRDS
LA English
DT Article
DE Charadrius melodus; epilimnetc; foraging; habitat; hypolimnetic;
Missouri River; Piping Plover; shorebird
ID MISSISSIPPI RIVER; HABITAT USE; SURVIVAL; ISLANDS
AB Selection of a foraging site entails costs and benefits which are reflected in survival and reproductive success. We studied Piping Plover (Charadrius melodus) foraging-site selection during the breeding season (2001-2003) On the Missouri River and examined the relationship between site selection and invertebrate abundance indices within habitats. Foraging adult plovers selected protected shoreline (inter-sandbar channels, inlets, and backwater areas) more often than expected based on availability (use: 92% +/- 3%; availability: 58% +/- 5%). Invertebrate biomass and numbers along exposed shoreline did not. differ among reaches. Along the protected shoreline, invertebrate biomass and numbers were higher below a dam with an epilimnetic release and a relatively constant release rate (epilimnetic reach) than at the other two reaches. On the epilimnetic river reach, invertebrate biomass and numbers were higher along the protected shoreline than on the main channel shoreline. On a reach below a dam with a hypolimnetic release and diel flow pulse (hypolimnetic reach) and a cold water reservoir, invertebrate indices were similar on the protected and exposed shoreline. Invertebrate numbers were higher in saturated and moist habitats than in vegetated and dry habitats (P < 0.05). At the epilimnetic and hypolimnetic reaches, foraging Piping Plover chicks used saturated and moist habitats more than vegetated and dry habitats, based on availability. On the Missouri River, protected shorelines were important foraging sites for Piping Plovers during the breeding season, and sandbars with low-lying moist habitat were important to foraging chicks. Piping Plovers will benefit from increased availability of these habitats on managed or created sandbars on the Missouri River. Received 9 September 2007, accepted June 2008.
C1 [Le Fer, Danielle; Fraser, James D.] Virginia Tech, Dept Fisheries & Wildlife Sci, Blacksburg, VA 24061 USA.
[Kruse, Casey D.] USA, Corps Engineers, Yankton, SD 57078 USA.
RP Le Fer, D (reprint author), San Francisco Bay Bird Observ, 524 Valley Way, Milpitas, CA 95035 USA.
EM dlefer@sfbbo.org
FU U.S. Army Corps of Engineers; U.S. Fish and Wildlife Service; South
Dakota Department of Fish and Game
FX We thank the U.S. Army Corps of Engineers, U.S. Fish and Wildlife
Service, and South Dakota Department of Fish and Game for their funding.
Special thanks to the inany technicians who helped NNrith the research.
NR 22
TC 9
Z9 10
U1 2
U2 8
PU WATERBIRD SOC
PI WASHINGTON
PA NATL MUSEUM NATURAL HISTORY SMITHSONIAN INST, WASHINGTON, DC 20560 USA
SN 1524-4695
J9 WATERBIRDS
JI Waterbirds
PD DEC
PY 2008
VL 31
IS 4
BP 587
EP 592
PG 6
WC Ornithology
SC Zoology
GA 401II
UT WOS:000262934000009
ER
PT J
AU Yeh, IC
Lee, MS
Olson, MA
AF Yeh, In-Chul
Lee, Michael S.
Olson, Mark A.
TI Calculation of Protein Heat Capacity from Replica-Exchange Molecular
Dynamics Simulations with Different Implicit Solvent Models
SO JOURNAL OF PHYSICAL CHEMISTRY B
LA English
DT Article
ID GENERALIZED BORN MODEL; HISTOGRAM ANALYSIS METHOD; FREE-ENERGY
LANDSCAPE; CENTERED DIELECTRIC FUNCTIONS; ALPHA-HELICAL PEPTIDES;
EXPLICIT SOLVENT; SH3 DOMAIN; FOLDING KINETICS; BETA-HAIRPIN; SOLVATION
AB The heat capacity has played a major role in relating microscopic and macroscopic properties of proteins and their disorder-order phase transition of folding. Its calculation by atomistic simulation methods remains a significant challenge due to the complex and dynamic nature of protein structures, their solvent environment, and configurational averaging. To better understand these factors on calculating a protein heat capacity, we provide a comparative analysis of simulation models that differ in their implicit solvent description and force-field resolution. Our model protein system is the src Homology 3 (SH3) domain of alpha-spectrin, and we report a series of 10 ns replica-exchange molecular dynamics simulations performed at temperatures ranging from 298 to 550 K, starting from the SH3 native structure. We apply the all-atom CHARMM22 force field with different modified analytical generalized Born solvent models (GBSW and GBMV2) and compare these simulation models with the distance-dependent dielectric screening of charge-charge interactions. A further comparison is provided with the united-atom CHARMM19 plus a pairwise GB model. Unfolding-folding transition temperatures of SH3 were estimated from the temperature-dependent profiles of the heat capacity, root-mean-square distance from the native structure, and the fraction of native contacts, each calculated from the density of states by using the weighted histogram analysis method. We observed that, for CHARMM22, the unfolding transition and energy probability density were quite sensitive to the implicit solvent description, in particular, the treatment of the protein-solvent dielectric boundary in GB models and their surface-area-based hydrophobic term. Among the solvent models tested, the calculated melting temperature varied in the range 353-438 K and was higher than the experimental value near 340 K. A reformulated GBMV2 model of employing a smoother molecular-volume dielectric interface was the most accurate in reproducing the native conformation and a two-state folding landscape, although the melting transition temperature did not show the smallest deviation from experiment. For the lower-resolution CHARMM19/GB model, the simulations failed to yield a bimodal energy distribution, yet the melting temperature was observed to be a good estimate of higher-resolution simulation models. We also demonstrate that a careful analysis of a relatively long simulation is necessary to avoid trapping in local minima and to find a true thermodynamic transition temperature.
C1 [Lee, Michael S.; Olson, Mark A.] USA, Med Res Inst Infect Dis, Dept Biochem & Cell Biol, Ft Detrick, MD 21702 USA.
[Yeh, In-Chul; Lee, Michael S.] USA, Med Res & Mat Command, Telemed & Adv Technol Res Ctr, Biotechnol High Performance Comp Software Applica, Frederick, MD 21702 USA.
[Lee, Michael S.] USA, Res Lab, Computat & Informat Sci Directorate, Aberdeen Proving Ground, MD 21005 USA.
RP Olson, MA (reprint author), USA, Med Res Inst Infect Dis, Dept Biochem & Cell Biol, Ft Detrick, MD 21702 USA.
EM molson@ncifcrf.gov
FU Department of Defense High Performance Computing (HPC) Modernization
Program Office [21248, 132259]
FX Acknowledgment. We thank Dr. M. Feig and Dr. A. Wallqvist for helpful
discussions, and also Dr. E. Gallicchio and Dr. R. Levy for making their
software code available to us for estimating statistical uncertainties.
Funding support for this work came from the Department of Defense High
Performance Computing (HPC) Modernization Program Office, under the HPC
Software Application Institute initiative, and the Army Medical Research
and Materiel Command (Project Nos. 21248 and 132259). Computational time
was provided by the U.S. Army Research Laboratory Major Shared Resource
Center and the Advanced Biomedical Computing Center at the National
Cancer Institute. Opinions, interpretations, conclusions, and
recommendations are those of the authors and are not necessarily
endorsed by the U.S. Army.
NR 61
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Z9 20
U1 0
U2 9
PU AMER CHEMICAL SOC
PI WASHINGTON
PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
SN 1520-6106
J9 J PHYS CHEM B
JI J. Phys. Chem. B
PD NOV 27
PY 2008
VL 112
IS 47
BP 15064
EP 15073
DI 10.1021/jp802469g
PG 10
WC Chemistry, Physical
SC Chemistry
GA 374PO
UT WOS:000261056400047
PM 18959439
ER
PT J
AU Liu, CH
He, HY
Pandey, R
Hussain, S
Karna, SP
AF Liu, Chunhui
He, Haiying
Pandey, Ravindra
Hussain, Saber
Karna, Shashi P.
TI Interaction of Metallic Nanoparticles with a Biologically Active
Molecule, Dopamine
SO JOURNAL OF PHYSICAL CHEMISTRY B
LA English
DT Article
ID AUGMENTED-WAVE METHOD; AQUEOUS-SOLUTION; CLUSTERS; NANOMATERIALS;
CONFORMATION; DYNAMICS
AB We present the results of first-principles molecular orbital calculations describing the interaction of metallic nanoparticles, represented by Mn-13, Ag-13, and Al-13 atomic clusters, with a biologically active molecule, dopamine. The interaction strength, determined in terms of the nanoparticle-molecule complex binding energy, is found to be higher for Mn than either Ag or Al and can be explained in terms of the degree of the hybridization of the (metal) atomic orbitals with the molecular orbitals in the complex. Furthermore, smaller interaction strength of these metallic nanoparticles with water compared to that with dopamine predicts the preference of forming a complex of dopamine with the metallic nanoparticles in the aqueous solution. The calculated results may therefore suggest that the presence of these metallic nanoparticles could induce different levels of dopamine depletion in solution.
C1 [Liu, Chunhui; He, Haiying; Pandey, Ravindra] Michigan Technol Univ, Dept Phys, Houghton, MI 49931 USA.
[Liu, Chunhui; He, Haiying; Pandey, Ravindra] Michigan Technol Univ, Multiscale Technol Inst, Houghton, MI 49931 USA.
[Hussain, Saber] USAF, Res Lab, Dayton, OH USA.
[Karna, Shashi P.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Pandey, R (reprint author), Michigan Technol Univ, Dept Phys, Houghton, MI 49931 USA.
EM pandey@mtu.edu
FU DARPA [ARL-DAAD 17-03-C-0115]
FX Helpful discussions with R. Scheicher, S. Gowtham, and K. C. Lau are
acknowledged. The work at Michigan Technological University was
supported by DARPA (contract No. ARL-DAAD 17-03-C-0115).
NR 29
TC 9
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U1 0
U2 4
PU AMER CHEMICAL SOC
PI WASHINGTON
PA 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
SN 1520-6106
J9 J PHYS CHEM B
JI J. Phys. Chem. B
PD NOV 27
PY 2008
VL 112
IS 47
BP 15256
EP 15259
DI 10.1021/jp808009t
PG 4
WC Chemistry, Physical
SC Chemistry
GA 374PO
UT WOS:000261056400068
PM 18983187
ER
PT J
AU Neff, RT
Hurst, FP
Falta, EM
Bohen, EM
Lentine, KL
Dharnidharka, VR
Agodoa, LY
Jindal, RM
Yuan, CM
Abbott, KC
AF Neff, Robert T.
Hurst, Frank P.
Falta, Edward M.
Bohen, Erin M.
Lentine, Krista L.
Dharnidharka, Vikas R.
Agodoa, Lawrence Y.
Jindal, Rahul M.
Yuan, Christina M.
Abbott, Kevin C.
TI Progressive Multifocal Leukoencephalopathy and Use of Mycophenolate
Mofetil After Kidney Transplantation
SO TRANSPLANTATION
LA English
DT Article
DE Kidney transplant; Mycophenolate mofetil; Progressive multifocal
leukoencephalopathy
ID VIRUS VP1 POLYPEPTIDES; RENAL-TRANSPLANTATION; BK VIRUS; RECIPIENT;
NEPHROPATHY; PATIENT; DISEASE; PML
AB Mycophenolate mofetil (MMF) use may be associated with progressive multifocal leukoencephalopathy (PML). We conducted a retrospective cohort study of 32,757 renal transplant recipients using the United States Renal Data System kidney transplant files for the incidence, prognosis, and clinical features associated with PML Occurring after kidney transplant. Subjects were transplanted from January 1, 2000 to July 31, 2004 and followed through December 31, 2004. The incidence density of PML in MMF users was 14.4 cases/100,000 person-years at risk versus 0 for non-MMF users (P=0.11) by log rank test. Factors significantly associated with PML were BK virus infection (22.2% vs. 1.1%), pretransplant transfusion (75% vs. 34%), panel reactive antibody more than 20% (56% vs. 14%), and use of antirejection medications in the first year (33% vs. 9.2%), all P less than 0.05. PML is rare in the renal transplant population. There was no significant association between PML and MMF, but MMF use in this cohort is too high to accurately assess an association.
C1 [Neff, Robert T.; Hurst, Frank P.; Bohen, Erin M.; Yuan, Christina M.; Abbott, Kevin C.] Walter Reed Army Med Ctr, Serv Nephrol, Washington, DC 20307 USA.
[Falta, Edward M.; Jindal, Rahul M.] Walter Reed Army Med Ctr, Organ Transplant Serv, Washington, DC 20307 USA.
[Lentine, Krista L.] St Louis Univ, Sch Med, Ctr Outcomes Res, Div Nephrol, St Louis, MO USA.
[Dharnidharka, Vikas R.] Univ Florida, Coll Med, Dept Pediat, Gainesville, FL USA.
[Agodoa, Lawrence Y.] NIDDKD, NIH, Bethesda, MD 20892 USA.
[Jindal, Rahul M.] Brookdale Univ Hosp, Dept Surg, Brooklyn, NY USA.
RP Neff, RT (reprint author), Walter Reed Army Med Ctr, Serv Nephrol, Washington, DC 20307 USA.
EM robert.neff@amedd.army.mil
OI Abbott, Kevin/0000-0003-2111-7112
NR 26
TC 77
Z9 77
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0041-1337
J9 TRANSPLANTATION
JI Transplantation
PD NOV 27
PY 2008
VL 86
IS 10
BP 1474
EP 1478
DI 10.1097/TP.0b013e31818b62c8
PG 5
WC Immunology; Surgery; Transplantation
SC Immunology; Surgery; Transplantation
GA 377XL
UT WOS:000261285600023
PM 19034021
ER
PT J
AU Klein, RJ
Cole, SM
Belcher, ME
Schroeder, JL
Cole, PJ
Lenhart, JL
AF Klein, Robert J.
Cole, Shannon M.
Belcher, Michael E.
Schroeder, John L.
Cole, Phillip J.
Lenhart, Joseph L.
TI Radiation tolerance in polymeric dielectrics by small-molecule doping,
Part I: Dopant uptake as a function of temperature, time, and chemistry
SO POLYMER
LA English
DT Article
DE Radiation; Polymer; Conductivity
ID INDUCED CONDUCTIVITY; POLYETHYLENE TEREPHTHALATE; HETEROGENEOUS SYSTEMS;
SORPTION-DIFFUSION; ELECTRON-TRANSPORT; AMORPHOUS POLYMERS; FILMS;
ADSORPTION; BATTERIES; MEMBRANES
AB The doping of Mylar (R) film (composed of semi-crystalline poly(ethylene terephthalate)) with small-molecule electron traps results in a high-quality dielectric film with excellent radiation tolerance. This paper, the first of two, investigates the doping process as small molecules are implanted into the film from a solution of ethylene glycol over time. A series of fluorenone-based dopants are investigated, functionalized by nitro or cyano groups. The concentration of dopant in the Mylar (R) is a strong function of time, temperature, and solution concentration. Doping is ineffective below the glass transition temperature of the polymer. The chemical functionality of the dopant had a strong effect on the doping process, with additional nitro or cyano groups leading to enhanced film concentrations. (C) 2008 Published by Elsevier Ltd.
C1 [Cole, Phillip J.] Sandia Natl Labs, NNSA Satellite Programs 5732, Albuquerque, NM 87185 USA.
[Klein, Robert J.; Schroeder, John L.; Lenhart, Joseph L.] Sandia Natl Labs, Organ Mat Dept 1821, Albuquerque, NM 87185 USA.
[Cole, Shannon M.; Belcher, Michael E.] Sandia Natl Labs, Organ Mat Dept 2453, Albuquerque, NM 87185 USA.
[Lenhart, Joseph L.] USA, Army Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA.
RP Cole, PJ (reprint author), Sandia Natl Labs, NNSA Satellite Programs 5732, POB 5800, Albuquerque, NM 87185 USA.
EM pjcole@sandia.gov; joseph.lenhart1@arl.army.mil
FU Sandia Corporation; Lockheed Martin Company; United States Department of
Energy's National Nuclear Security Administration [DE-AC04-94AL85000]
FX Sandia is a multiprogram laboratory operated by Sandia Corporation, a
Lockheed Martin Company, for the United States Department of Energy's
National Nuclear Security Administration under contract
DE-AC04-94AL85000. Thanks to Mark Stavig for his assistance with the DSC
and DMA.
NR 44
TC 2
Z9 4
U1 0
U2 6
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0032-3861
J9 POLYMER
JI Polymer
PD NOV 24
PY 2008
VL 49
IS 25
BP 5541
EP 5548
DI 10.1016/j.polymer.2008.08.067
PG 8
WC Polymer Science
SC Polymer Science
GA 380JU
UT WOS:000261462800024
ER
PT J
AU Weiss, BM
Verma, P
Abadie, J
Howard, R
Kuehl, M
AF Weiss, Brendan M.
Verma, Pramvir
Abadie, Jude
Howard, Robin
Kuehl, Michael
TI A Pre-Existing Plasma Cell Disorder Occurs in Most Patients with
Multiple Myeloma
SO BLOOD
LA English
DT Meeting Abstract
CT 50th Annual Meeting of the American-Society-of-Hematology
CY DEC 06-09, 2008
CL San Francisco, CA
SP Amer Soc Hematol
C1 [Weiss, Brendan M.] Walter Reed Army Med Ctr, Hematol Oncol Serv, Washington, DC 20307 USA.
[Verma, Pramvir] Womack Army Med Ctr, Hematol Oncol Serv, Ft Bragg, NC USA.
[Abadie, Jude] Walter Reed Army Med Ctr, Pathol & Area Lab Serv, Washington, DC 20307 USA.
[Howard, Robin] Walter Reed Army Med Ctr, Dept Clin Invest, Washington, DC 20307 USA.
[Kuehl, Michael] Natl Canc Inst, Genet Branch, Ctr Canc Res, Bethesda, MD USA.
NR 0
TC 0
Z9 0
U1 0
U2 0
PU AMER SOC HEMATOLOGY
PI WASHINGTON
PA 1900 M STREET. NW SUITE 200, WASHINGTON, DC 20036 USA
SN 0006-4971
J9 BLOOD
JI Blood
PD NOV 16
PY 2008
VL 112
IS 11
BP 598
EP 598
PG 1
WC Hematology
SC Hematology
GA 389OP
UT WOS:000262104702027
ER
PT J
AU Okatan, MB
Cole, MW
Alpay, SP
AF Okatan, M. B.
Cole, M. W.
Alpay, S. P.
TI Dielectric tunability of graded barium strontium titanate multilayers:
Effect of thermal strains
SO JOURNAL OF APPLIED PHYSICS
LA English
DT Article
DE barium compounds; ferroelectric materials; multilayers; numerical
analysis; permittivity; strontium compounds; tensile strength; thermal
expansion; thermodynamics
ID FERROELECTRIC THIN-FILMS; PHASE-TRANSITIONS; TECHNOLOGY; COMPONENTS;
PARAMETER; DIAGRAMS; STRESSES; SRTIO3
AB A thermodynamic model was developed to analyze the effect of the difference in the thermal expansion coefficient (TEC) of a multilayered barium strontium titanate Ba1-ySryTiO3 (BST) ferroelectric heterostructure and a passive substrate on the dielectric properties by taking into account electrostatic and electromechanical interactions between the ferroelectric layers. Results show that the dielectric constant and tunability can be maximized by minimizing the TEC mismatch. Furthermore, lower processing temperatures lead to lower thermal strains and thus to better dielectric properties. We also provide a numerical analysis describing the effect of thermal strains on dielectric properties of a compositionally graded trilayer consisting of BST 60/40, BST 75/25, and BST 90/10 on a variety of substrates including Si, sapphire (alpha-Al2O3), SrTiO3, MgO, and LaAlO3. The multilayer BST heterostructure on Si is expected to experience high in-plane tensile strains due to the large TEC mismatch, resulting in dielectric permittivities and tunabilities lower compared to the same multilayer on SrTiO3 or LaAlO3 for which there is a better TEC match. For BST multilayers on MgO, SrTiO3, Si, and sapphire, higher processing temperatures lead to lower dielectric response and tunability.
C1 [Okatan, M. B.; Alpay, S. P.] Univ Connecticut, Mat Sci & Engn Program, Dept Chem Mat & Biomol Engn, Storrs, CT 06269 USA.
[Okatan, M. B.; Alpay, S. P.] Univ Connecticut, Inst Mat Sci, Storrs, CT 06269 USA.
[Cole, M. W.] USA, Res Lab, Weap & Mat Res Directorate, Aberdeen Proving Ground, MD 21005 USA.
RP Alpay, SP (reprint author), Univ Connecticut, Mat Sci & Engn Program, Dept Chem Mat & Biomol Engn, Storrs, CT 06269 USA.
EM mcole@arl.army.mil; p.alpay@ims.uconn.edu
RI Alpay, Pamir/E-2666-2013; Okatan, M. Baris/E-1913-2016
OI Okatan, M. Baris/0000-0002-9421-7846
FU U. S. Army Research Office [W911NF-05-1-0528, W911NF-08-C-0124]
FX The work at UConn was supported by the U. S. Army Research Office
through Grant Nos. W911NF-05-1-0528 and W911NF-08-C-0124.
NR 34
TC 29
Z9 29
U1 6
U2 30
PU AMER INST PHYSICS
PI MELVILLE
PA 1305 WALT WHITMAN RD, STE 300, MELVILLE, NY 11747-4501 USA
SN 0021-8979
EI 1089-7550
J9 J APPL PHYS
JI J. Appl. Phys.
PD NOV 15
PY 2008
VL 104
IS 10
AR 104107
DI 10.1063/1.3026719
PG 7
WC Physics, Applied
SC Physics
GA 396QI
UT WOS:000262605800110
ER
PT J
AU Sandstrom, E
Nilsson, C
Hejdeman, B
Brave, A
Bratt, G
Robb, M
Cox, J
VanCott, T
Marovich, M
Stout, R
Aboud, S
Bakari, M
Pallangyo, K
Ljungberg, K
Moss, B
Earl, P
Michael, N
Birx, D
Mhalu, F
Wahren, B
Biberfeld, G
AF Sandstrom, Eric
Nilsson, Charlotta
Hejdeman, Bo
Brave, Andreas
Bratt, Goran
Robb, Merlin
Cox, Josephine
VanCott, Thomas
Marovich, Mary
Stout, Richard
Aboud, Said
Bakari, Muhammad
Pallangyo, Kisali
Ljungberg, Karl
Moss, Bernard
Earl, Patricia
Michael, Nelson
Birx, Deborah
Mhalu, Fred
Wahren, Britta
Biberfeld, Gunnel
CA HIV Immunogenicity Study 01 02 Tea
TI Broad Immunogenicity of a Multigene, Multiclade HIV-1 DNA Vaccine
Boosted with Heterologous HIV-1 Recombinant Modified Vaccinia Virus
Ankara
SO JOURNAL OF INFECTIOUS DISEASES
LA English
DT Article; Proceedings Paper
CT 6th Annual International AIDS Vaccine Conference
CY AUG 20-23, 2007
CL Seattle, WA
ID CD8(+) T-CELL; COLONY-STIMULATING FACTOR; HEPATITIS-B VACCINATION;
CANDIDATE VACCINE; IMMUNE-RESPONSES; PHASE-1 SAFETY; AIDS RESEARCH;
EPITOPES; REGIMEN; CLADE
AB Background. A human immunodeficiency virus (HIV) vaccine that limits disease and transmission is urgently needed. This clinical trial evaluated the safety and immunogenicity of an HIV vaccine that combines a plasmid-DNA priming vaccine and a modified vaccinia virus Ankara (MVA) boosting vaccine. Methods. Forty healthy volunteers were injected with DNA plasmids containing gp160 of HIV-1 subtypes A, B, and C; rev B; p17/p24 gag A and B, and RTmut B by use of a needle-free injection system. The vaccine was administered intradermally or intramuscularly, with or without recombinant granulocyte macrophage colony-stimulating factor, and boosted with a heterologousMVAcontaining env, gag, and pol of CRF01A_ E. Immune responses were monitored with HIV-specific interferon (IFN)-gamma and interleukin (IL)-2 ELISpot and lymphoproliferative assays (LPAs). Results. Vaccine-related adverse events were mild and tolerable. After receipt of the DNA priming vaccine, 11 (30%) of 37 vaccinees had HIV-specific IFN-gamma responses. After receipt of the MVA boosting vaccine, ELISpot assays showed that 34 (92%) of 37 vaccinees had HIV-specific IFN-gamma responses, 32 (86%) to Gag and 24 ( 65%) to Env. IFN-gamma production was detected in both the CD8(+) T cell compartment ( 5 of 9 selected vaccinees) and the CD4(+) T cell compartment ( 9 of 9). ELISpot results showed that 25 ( 68%) of 37 vaccinees had a positive IL-2 response and 35 ( 92%) of 38 had a positive LPA response. Of 38 subjects, a total of 37 (97%) were responders. One milligram of HIV-1 DNA administered intradermally was as effective as 4mg administered intramuscularly in priming for the MVA boosting vaccine. Conclusion. This HIV-DNA priming-MVA boosting approach is safe and highly immunogenic.
C1 [Ljungberg, Karl] Karolinska Inst, Dept Oncol Pathol, S-11883 Stockholm, Sweden.
[Nilsson, Charlotta; Brave, Andreas; Wahren, Britta; Biberfeld, Gunnel] Karolinska Inst, Swedish Inst Infect Dis Control, S-11883 Stockholm, Sweden.
[Robb, Merlin; Cox, Josephine; VanCott, Thomas; Marovich, Mary; Michael, Nelson; Birx, Deborah] Walter Reed Army Inst Res, Dept Retrovirol, Rockville, MD USA.
[Moss, Bernard; Earl, Patricia] NIAID, Viral Dis Lab, NIH, Bethesda, MD 20892 USA.
[Stout, Richard] Bioject, Portland, OR USA.
[Aboud, Said; Bakari, Muhammad; Pallangyo, Kisali; Mhalu, Fred] Muhimbili Univ Hlth & Allied Sci, Dar Es Salaam, Tanzania.
[Nilsson, Charlotta; Brave, Andreas; Wahren, Britta; Biberfeld, Gunnel] Karolinska Inst, Dept Microbiol & Tumor & Cell Biol, S-11883 Stockholm, Sweden.
[Sandstrom, Eric; Hejdeman, Bo; Bratt, Goran] Karolinska Inst, Soder Sjukhuset, Dept Clin Sci & Educ, S-11883 Stockholm, Sweden.
RP Wahren, B (reprint author), Karolinska Inst, Soder Sjukhuset, Dept Clin Sci & Educ, S-11883 Stockholm, Sweden.
EM Eric.sandstrom@sodersjukhuset.se; Britta.Wahren@smi.ki.se
OI Ljungberg, Karl/0000-0001-7192-6204
FU Intramural NIH HHS [Z01 AI000416-25]
NR 34
TC 99
Z9 100
U1 2
U2 9
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 1537-6613
J9 J INFECT DIS
JI J. Infect. Dis.
PD NOV 15
PY 2008
VL 198
IS 10
BP 1482
EP 1490
DI 10.1086/592507
PG 9
WC Immunology; Infectious Diseases; Microbiology
SC Immunology; Infectious Diseases; Microbiology
GA 366HW
UT WOS:000260472400010
PM 18808335
ER
PT J
AU Cardoso, MJ
Dmitriev, AE
Lehman, RA
Helgeson, M
Cooper, P
Rosner, MK
AF Cardoso, Mario J.
Dmitriev, Anton E.
Lehman, Ronald A.
Helgeson, Melvin
Cooper, Patrick
Rosner, Michael K.
TI Computed Tomography and Biomechanical Evaluation of Screw Fixation
Options at the Cervicothoracic Junction Intralamina Versus
Intrapedicular Techniques
SO SPINE
LA English
DT Article
DE cervicothoracic junction; lamina screw; pedicle screw; salvage technique
ID BONE-MINERAL DENSITY; UPPER THORACIC SPINE; PEDICLE SCREWS;
STRAIGHT-FORWARD; PLACEMENT; VERTEBRAE; FAILURE
AB Study Design. In vitro cadaveric biomechanical analysis.
Objective. Define the T1 and T2 anatomic lamina size and evaluate the bone-screw interface strength of various pedicle screw options and intralamina techniques.
Summary of Background Data. Transpedicular instrumentation is well accepted, but salvage techniques in the proximal thoracic spine are limited. Intralamina fixation has been described at C2 with favorable biomechanical characteristics. In addition, this technique has been introduced clinically in the proximal thoracic spine. However, the biomechanical potential has not been evaluated.
Methods. Fourteen fresh-frozen cervicothoracic cadaveric specimens were scanned using dual-energy radiograph absorptiometry for bone mineral density, imaged under computed tomography, and then instrumented in the following configuration: (1) Right-sided pedicle screws in a straight-forward trajectory, (2) "salvage anatomic trajectory pedicle screws, and (3) "salvage" intralamina screws into the contralateral lamina. Insertional torque (IT) was recorded with each revolution and screws were pulled out in-line (POS) with the screw axis to simulate intraoperative failure of fixation.
Results. Lamina screws as a salvage technique generated statistically greater peak IT (P = 0.002) and relative POS (P < 0.05) in comparison with straight-forward transpedicular screws as the initial fixation type. Furthermore, lamina screws, when compared to the salvage anatomic trajectory pedicle screws, had a significantly greater peak IT (P = 0.011). The peak IT showed a stronger correlation with POS in lamina screws than straight-forward or anatomic pedicle screws with a similar trend noted in mean IT. Bone mineral density correlated with POS in all methods of fixation. The mean lamina width measured on computed tomography at the thinnest point was 5.9 +/- 0.7 mm (range, 4.9-7.9).
Conclusion. Our results suggest that lamina screws, used as a salvage technique in the proximal thoracic spine, provide stronger fixation than transpedicular screws when using standard 4.5-mm cervical screws. Intralamina screws appear to be a biomechanically sound salvage technique in the region, and appear to be a safe, effective technique for instrumenting the proximal thoracic spine.
C1 [Cardoso, Mario J.; Cooper, Patrick; Rosner, Michael K.] Walter Reed Army Med Ctr, Neurosurg Serv, Dept Surg, Washington, DC 20307 USA.
[Dmitriev, Anton E.; Lehman, Ronald A.; Helgeson, Melvin] Walter Reed Army Med Ctr, Dept Orthoped & Rehabil, Washington, DC 20307 USA.
RP Cardoso, MJ (reprint author), Walter Reed Army Med Ctr, Neurosurg Serv, Dept Surg, 6900 Georgia Ave NW, Washington, DC 20307 USA.
EM mtcardoso@comcast.net
NR 19
TC 11
Z9 14
U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0362-2436
J9 SPINE
JI SPINE
PD NOV 15
PY 2008
VL 33
IS 24
BP 2612
EP 2617
DI 10.1097/BRS.0b013e31818ce3ac
PG 6
WC Clinical Neurology; Orthopedics
SC Neurosciences & Neurology; Orthopedics
GA 373ZG
UT WOS:000261011400006
PM 19011542
ER
PT J
AU Leon, LR
AF Leon, Lisa R.
TI Thermoregulatory responses to environmental toxicants: The interaction
of thermal stress and toxicant exposure
SO TOXICOLOGY AND APPLIED PHARMACOLOGY
LA English
DT Review
DE Toxicology; Hypothermia; Fever; Heat stress; Organophosphates
ID BROWN ADIPOSE-TISSUE; TUMOR-NECROSIS-FACTOR; METAL FUME FEVER;
BODY-TEMPERATURE; PERCUTANEOUS-ABSORPTION; INDUCED HYPOTHERMIA;
HEAT-STROKE; IN-VITRO; DIISOPROPYL FLUOROPHOSPHATE;
CHOLINESTERASE-INHIBITORS
AB Thermal stress can have a profound impact on the physiological responses that are elicited following environmental toxicant exposure. The efficacy by which toxicants enter the body is directly influenced by thermoregulatory effector responses that are evoked in response to high ambient temperatures. In mammals, the thermoregulatory response to heat stress consists of an increase in skin blood flow and moistening of the skin surface to dissipate core heat to the environment. These physiological responses may exacerbate chemical toxicity due to increased permeability of the skin, which facilitates the cutaneous absorption of many environmental toxicants. The core temperature responses that are elicited in response to high ambient temperatures, toxicant exposure or both can also have a profound impact on the ability of an organism to survive the insult. In small rodents. the thermoregulatory response to thermal stress and many environmental toxicants (such as organophosphate compounds) is often biphasic in nature, consisting initially of a regulated reduction in core temperature (i.e., hypothermia) followed by fever. Hypothermia is an important thermoregulatory survival stratey that is used by small rodents to diminish the effect of severe environmental insults on tissue homeostasis. The protective effect of hypothermia is realized by its effects on chemical toxicity as molecular and cellular processes, such as lipid peroxidation and the formation of reactive oxygen species, are minimized at reduced core temperatures. The beneficial effects of fever are unknown under these conditions. Perspective is provided on the applicability of data obtained in rodent models to the human condition. Published by Elsevier Inc.
C1 USA, Environm Med Res Inst, Thermal & Mt Med Div, Natick, MA 01760 USA.
RP Leon, LR (reprint author), USA, Environm Med Res Inst, Thermal & Mt Med Div, Kansas St,Bldg 42, Natick, MA 01760 USA.
EM lisa.r.leon@us.army.mil
NR 151
TC 19
Z9 20
U1 1
U2 7
PU ACADEMIC PRESS INC ELSEVIER SCIENCE
PI SAN DIEGO
PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA
SN 0041-008X
J9 TOXICOL APPL PHARM
JI Toxicol. Appl. Pharmacol.
PD NOV 15
PY 2008
VL 233
IS 1
BP 146
EP 161
DI 10.1016/j.taap.2008.01.012
PG 16
WC Pharmacology & Pharmacy; Toxicology
SC Pharmacology & Pharmacy; Toxicology
GA 380PO
UT WOS:000261477800024
PM 18313713
ER
PT J
AU Mahajan, B
Selvapandiyan, A
Gerald, NJ
Majam, V
Zheng, H
Wickramarachchi, T
Tiwari, J
Fujioka, H
Moch, JK
Kumar, N
Aravind, L
Nakhasi, HL
Kumar, S
AF Mahajan, Babita
Selvapandiyan, Angamuthu
Gerald, Noel J.
Majam, Victoria
Zheng, Hong
Wickramarachchi, Thilan
Tiwari, Jawahar
Fujioka, Hisashi
Moch, J. Kathleen
Kumar, Nirbhay
Aravind, L.
Nakhasi, Hira L.
Kumar, Sanjai
TI Centrins, Cell Cycle Regulation Proteins in Human Malaria Parasite
Plasmodium falciparum
SO JOURNAL OF BIOLOGICAL CHEMISTRY
LA English
DT Article
ID SPINDLE POLE BODY; CHLAMYDOMONAS-REINHARDTII; CALCIUM-BINDING;
SACCHAROMYCES-CEREVISIAE; LEISHMANIA-DONOVANI; MAXIMUM-LIKELIHOOD;
TRYPANOSOMA-BRUCEI; MURINE CENTRIN; GENE; DUPLICATION
AB Molecules and cellular mechanisms that regulate the process of cell division in malaria parasites remain poorly understood. In this study we isolate and characterize the four Plasmodium falciparum centrins (PfCENs) and, by growth complementation studies, provide evidence for their involvement in cell division. Centrins are cytoskeleton proteins with key roles in cell division, including centrosome duplication, and possess four Ca2+-binding EF hand domains. By means of phylogenetic analysis, we were able to decipher the evolutionary history of centrins in eukaryotes with particular emphasis on the situation in apicomplexans and other alveolates. Plasmodium possesses orthologs of four distinct centrin paralogs traceable to the ancestral alveolate, including two that are unique to alveolates. By real time PCR and/or immunofluorescence, we determined the expression of PfCEN mRNA or protein in sporozoites, asexual blood forms, gametocytes, and in the oocysts developing inside mosquito mid-gut. Immunoelectron microscopy studies showed that centrin is expressed in close proximity with the nucleus of sporozoites and asexual schizonts. Furthermore, confocal and widefield microscopy using the double staining with alpha-tubulin and centrin antibodies strongly suggested that centrin is associated with the parasite centrosome. Following the episomal expression of the four PfCENs in a centrin knock-out Leishmania donovani parasite line that exhibited a severe growth defect, one of the PfCENs was able to partially restore Leishmania growth rate and overcome the defect in cytokinesis in such mutant cell line. To our knowledge, this study is the first characterization of a Plasmodium molecule that is involved in the process of cell division. These results provide the opportunity to further explore the role of centrins in cell division in malaria parasites and suggest novel targets to construct genetically modified, live attenuated malaria vaccines.
C1 [Kumar, Sanjai] US FDA, CBER, DETTD, OBRR, Rockville, MD 20852 USA.
[Tiwari, Jawahar] US FDA, Ctr Biol Evaluat & Res, Div Biostat, Rockville, MD 20852 USA.
[Fujioka, Hisashi] Case Western Reserve Univ, Dept Pharmacol, Cleveland, OH 44106 USA.
[Moch, J. Kathleen] Walter Reed Army Inst Res, Dept Immunol, Silver Spring, MD 20910 USA.
[Kumar, Nirbhay] Bloomberg Sch Publ Hlth, Dept Mol Microbiol & Immunol, Baltimore, MD 21205 USA.
[Aravind, L.] Natl Lib Med, Natl Ctr Biotechnol Informat, NIH, Bethesda, MD 20892 USA.
RP Kumar, S (reprint author), US FDA, CBER, DETTD, OBRR, 1401 Rockville Pike HFM-313, Rockville, MD 20852 USA.
EM sanjai.kumar@fda.hhs.gov
NR 64
TC 19
Z9 20
U1 0
U2 3
PU AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
PI BETHESDA
PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3996 USA
SN 0021-9258
EI 1083-351X
J9 J BIOL CHEM
JI J. Biol. Chem.
PD NOV 14
PY 2008
VL 283
IS 46
BP 31871
EP 31883
DI 10.1074/jbc.M800028200
PG 13
WC Biochemistry & Molecular Biology
SC Biochemistry & Molecular Biology
GA 370KJ
UT WOS:000260760800070
PM 18693242
ER
PT J
AU Winemiller, MD
Bae, SY
AF Winemiller, Mark D.
Bae, Sue Y.
TI Liquid chromatography-time-of-flight mass spectrometry analysis of
1-(2-chloroethoxy)-2-[(2-chloroethyl)thio] ethane and related compounds:
Separation of an eleven component mixture
SO JOURNAL OF CHROMATOGRAPHY A
LA English
DT Article
DE Liquid chromatography; Mass spectrometry; Sulfur mustard; Hydrolysis
ID CHEMICAL WARFARE AGENTS; ELECTROSPRAY-IONIZATION; DEGRADATION-PRODUCTS;
2-CHLOROETHYL SULFIDES; MUSTARD; IDENTIFICATION; HYDROLYSIS; SOIL; GAS
AB A method of separation for an eleven component mixture comprised of 1-(2-chloroethoxy)-2-[(2-chloroethyl)thiol] ethane (4) and its derivatives has been developed using LC-time-of-flight-MS. All analytical figures of merit for compounds 1-11 have been determined. Compound 4 was examined in a substrate extraction study consisting of different sand and soil matrices, and a hydrolysis study of 4 on sand revealed an extremely complex degradation pathway which appeared to be concentration dependent. Substrate extraction and hydrolysis results where compared with sulfur mustard (HD). Published by Elsevier B.V.
C1 [Winemiller, Mark D.; Bae, Sue Y.] US Army Edgewood Res, Res & Technol Directorate, Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD 21010 USA.
RP Bae, SY (reprint author), US Army Edgewood Res, Res & Technol Directorate, Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD 21010 USA.
EM sue.bae@us.army.mil
NR 17
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Z9 0
U1 0
U2 2
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0021-9673
J9 J CHROMATOGR A
JI J. Chromatogr. A
PD NOV 14
PY 2008
VL 1210
IS 2
BP 185
EP 192
DI 10.1016/j.chroma.2008.09.050
PG 8
WC Biochemical Research Methods; Chemistry, Analytical
SC Biochemistry & Molecular Biology; Chemistry
GA 374WL
UT WOS:000261074300008
PM 18834989
ER
PT J
AU Brooks, MC
Wood, AL
Annable, MD
Hatfield, K
Cho, J
Holbert, C
Rao, RSC
Enfield, CG
Lynch, K
Smith, RE
AF Brooks, Michael C.
Wood, A. Lynn
Annable, Michael D.
Hatfield, Kirk
Cho, Jaehyun
Holbert, Charles
Rao, R. Suresh C.
Enfield, Carl G.
Lynch, Kira
Smith, Richard E.
TI Changes in contaminant mass discharge from DNAPL source mass depletion:
Evaluation at two field sites
SO JOURNAL OF CONTAMINANT HYDROLOGY
LA English
DT Article
DE DNAPL; Source-zone remediation; Remediation performance metrics;
Contaminant flux; Flux reduction; Passive flux meters; Integral pumping
test
ID AQUIFER REMEDIATION SYSTEMS; SOURCE STRENGTH FUNCTIONS; NONAQUEOUS PHASE
LIQUIDS; UNIFORM-FLOW FIELDS; SOURCE ZONES; GROUNDWATER CONTAMINATION;
CONCENTRATION RESPONSE; SCALE EVALUATION; POROUS-MEDIA; FLUX
AB Changes in contaminant fluxes resulting from aggressive remediation of dense nonaqueous phase liquid (DNAPL) source zone were investigated at two sites, one at Hill Air Force Base (AFB). Utah, and the other at Ft. Lewis Military Reservation, Washington. Passive Flux Meters (PFM) and a variation of the Integral Pumping Test (IPT) were used to measure fluxes in ten wells installed along a transect down-gradient of the trichloroethylene (TCE) source zone, and perpendicular to the mean groundwater flow direction. At both sites, groundwater and contaminant fluxes were measured before and after the source-zone treatment. The measured contaminant fluxes (J; ML(-2)T(-1)) were integrated across the well transect to estimate contaminant mass discharge (M(D); MT(-1)) from the source zone. Estimated MD before source treatment, based on both PFM and IPT methods, were similar to 76 g/day for TCE at the Hill AFB site; and similar to 640 g/day for TCE, and similar to 206 g/day for cis-dichloroethylene (DCE) at the R. Lewis site. TCE flux measurements made 1 year after source treatment at the Hill AFB site decreased to similar to 5 g/day. On the other hand, increased fluxes of DCE, a degradation byproduct of TCE, in tests subsequent to remediation at the Hill AFB site suggest enhanced microbial degradation after surfactant flooding. At the Ft. Lewis site, TCE mass discharge rates subsequent to remediation decreased to similar to 3 g/day for TCE and similar to 3 g/day for DCE similar to 1.8 years after remediation. At both field sites, PFM and IPT approaches provided comparable results for contaminant mass discharge rates, and show significant reductions (> 90%) in TCE mass discharge as a result of DNAPL mass depletion from the source zone. Published by Elsevier B.V.
C1 [Brooks, Michael C.; Wood, A. Lynn] US EPA, Natl Risk Management Res Lab, Ada, OK 74820 USA.
[Annable, Michael D.; Hatfield, Kirk; Cho, Jaehyun] Univ Florida, Interdisciplinary Program Hydrol Sci, Gainesville, FL 32611 USA.
[Holbert, Charles] CH2M Hill Inc, Salt Lake City, UT 84111 USA.
[Rao, R. Suresh C.] Purdue Univ, Sch Civil Engn, W Lafayette, IN 47907 USA.
[Enfield, Carl G.] US EPA, Natl Risk Management Res Lab, Cincinnati, OH 45268 USA.
[Lynch, Kira] US EPA, Seattle, WA 98101 USA.
[Smith, Richard E.] USA, Corps Engineers, Seattle, WA 98124 USA.
RP Brooks, MC (reprint author), US EPA, Natl Risk Management Res Lab, Ada, OK 74820 USA.
EM Brooks.Michael@epamail.epa.gov
FU Strategic Environmental Research and Development Program (SERDP)
FX The work upon which this paper is based was supported by the U.S.
Environmental Protection Agency through its Office of Research and
Development with funding provided by the Strategic Environmental
Research and Development Program (SERDP), a collaborative effort
involving the U.S. Environmental Protection Agency (EPA), the U.S.
Department of Energy (DOE), and the U.S. Department of Defense (DoD).
This paper has not been subjected to Agency review and, therefore, does
not necessarily reflect the views of the Agency and no official
endorsement should be inferred. The authors are grateful to Irene C.
Poyer, Purdue University, for the analysis of groundwater samples
collected during the IPTs; to Dr. Jimi Lee, now at the University of
California-Riverside, for providing an estimate of the stainless steel
well screen hydraulic conductivity; and to Jefferey Powers, US Army
Corps of Engineers, for assistance with data collected by US Army Corps
of Engineers. Review comments from Dr. Eva Davis, Kerr Research Center
(EPA) and two anonymous reviewers are greatly appreciated.
NR 56
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U1 4
U2 20
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0169-7722
J9 J CONTAM HYDROL
JI J. Contam. Hydrol.
PD NOV 14
PY 2008
VL 102
IS 1-2
BP 140
EP 153
DI 10.1016/j.jconhyd.2008.05.008
PG 14
WC Environmental Sciences; Geosciences, Multidisciplinary; Water Resources
SC Environmental Sciences & Ecology; Geology; Water Resources
GA 381IK
UT WOS:000261529100012
PM 18632182
ER
PT J
AU Abbott, KC
Bohen, EM
Hurst, FP
AF Abbott, Kevin C.
Bohen, Erin M.
Hurst, Frank P.
TI Oral Sodium Phosphate Drug Products and Renal Function
SO ARCHIVES OF INTERNAL MEDICINE
LA English
DT Letter
ID KIDNEY INJURY; RISK
C1 [Abbott, Kevin C.] Walter Reed Army Med Ctr, Dialysis & Nephrol Serv, Washington, DC 20307 USA.
RP Abbott, KC (reprint author), Walter Reed Army Med Ctr, Dialysis & Nephrol Serv, 6900 Georgia Ave, Washington, DC 20307 USA.
EM kevin.abbott@amedd.army.mil
NR 5
TC 0
Z9 0
U1 0
U2 3
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 515 N STATE ST, CHICAGO, IL 60610-0946 USA
SN 0003-9926
J9 ARCH INTERN MED
JI Arch. Intern. Med.
PD NOV 10
PY 2008
VL 168
IS 20
BP 2285
EP 2285
DI 10.1001/archinte.168.20.2285-a
PG 1
WC Medicine, General & Internal
SC General & Internal Medicine
GA 370XS
UT WOS:000260797000017
PM 19001210
ER
PT J
AU Price, JA
Rogers, JV
McDougal, JN
Shaw, MQ
Reid, FM
Kiser, RC
Graham, JS
AF Price, Jennifer A.
Rogers, James V.
McDougal, James N.
Shaw, Morgan Q.
Reid, Frances M.
Kiser, Robyn C.
Graham, John S.
TI Gene expression analysis of bromine-induced burns in porcine skin
SO TOXICOLOGY LETTERS
LA English
DT Article
DE Bromine; Skin; Porcine; Microarray
ID TOLL-LIKE RECEPTORS; GROWTH-FACTOR; CHEMOKINE RECEPTORS; CHEMICAL BURNS;
SULFUR MUSTARD; PLASMINOGEN-ACTIVATOR; MICROARRAY ANALYSIS;
DIABETIC-RATS; HIV-INFECTION; IMMUNE CELLS
AB Bromine is an industrial chemical that is irritating to the skin and causes Cutaneous burns. An important factor in selecting or developing an effective treatment is to understand the underlying molecular mechanisms of tissue damage and wound healing. This study used a weanling swine burn mode) and microarray analysis to evaluate the effect of exposure length and sampling times on the transcriptional changes in response to cutaneous bromine injury. Ventral abdominal sites (N= 4/treatment group) were exposed to 600 mu L undiluted bromine for 45 s or 8 min. At 24 h and 7 d post-exposure, total RNA front skin samples was isolated, processed, and hybridized to Affymetrix GeneChip (R) Porcine Genome Arrays. Expression analysis revealed that bromine exposure duration appeared to have less effect on the transcript changes than the sampling time. The percent transcripts changed at 24 h were similar (30%) whether having a 45 s or 8 min bromine exposure; percent transcripts changed at 7 d were also similar (62%) regardless of exposure length. However, only 13-14% of the transcripts were similar when comparing samples analyzed at 24 h and 7 d. Ingenuity Pathways Analysis (IPA) revealed six common biological functions among the top 10 functions of each experimental group, while canonical pathway analysis revealed I I genes that were commonly shared among 24 significantly altered signaling pathways. Additionally, there were 11 signaling pathways in which there were no commonly shared transcripts. The present study is an initial assessment of the transcriptional responses to cutaneous bromine exposure identifying molecular networks and genes that could serve as targets for developing therapeutics for bromine-induced skin injury. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
C1 [Price, Jennifer A.; Rogers, James V.; Shaw, Morgan Q.; Reid, Frances M.; Kiser, Robyn C.] Battelle Mem Inst, Biomed Res Ctr, Columbus, OH 43201 USA.
[McDougal, James N.] Wright State Univ, Dept Pharmacol & Toxicol, Dayton, OH 45435 USA.
[Graham, John S.] USA, Med Toxicol Branch, Analyt Toxicol Div, Med Res Inst Chem Def, Aberdeen Proving Ground, MD 21010 USA.
RP Rogers, JV (reprint author), Battelle Mem Inst, Biomed Res Ctr, 505 King Ave JM-7, Columbus, OH 43201 USA.
EM rogersjv@battelle.org
FU DTRA/CBMS/MRMC [W81XWH-05-D-0001]
FX This work was Supported by DTRA/CBMS/MRMC Contract W81XWH-05-D-0001,
Task Order 0010. The authors thank Erin McGuinness for her excellent
technical assistance.
NR 73
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U1 0
U2 0
PU ELSEVIER IRELAND LTD
PI CLARE
PA ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000,
IRELAND
SN 0378-4274
J9 TOXICOL LETT
JI Toxicol. Lett.
PD NOV 10
PY 2008
VL 182
IS 1-3
BP 69
EP 78
DI 10.1016/j.toxlet.2008.08.007
PG 10
WC Toxicology
SC Toxicology
GA 377XN
UT WOS:000261285800012
PM 18790026
ER
PT J
AU Patch, JR
Han, ZY
McCarthy, SE
Yan, LY
Wang, LF
Harty, RN
Broder, CC
AF Patch, Jared R.
Han, Ziying
McCarthy, Sarah E.
Yan, Lianying
Wang, Lin-Fa
Harty, Ronald N.
Broder, Christopher C.
TI The YPLGVG sequence of the Nipah virus matrix protein is required for
budding
SO VIROLOGY JOURNAL
LA English
DT Article
ID INFECTIOUS-ANEMIA VIRUS; UBIQUITIN-PROTEASOME SYSTEM; VESICULAR
STOMATITIS-VIRUS; LATE ASSEMBLY DOMAIN; HOST PROTEINS; C-PROTEIN;
BINDING PARTNER; FLYING-FOXES; VP40 PROTEIN; PARTICLES
AB Background: Nipah virus (NiV) is a recently emerged paramyxovirus capable of causing fatal disease in a broad range of mammalian hosts, including humans. Together with Hendra virus (HeV), they comprise the genus Henipavirus in the family Paramyxoviridae. Recombinant expression systems have played a crucial role in studying the cell biology of these Biosafety Level-4 restricted viruses. Henipavirus assembly and budding occurs at the plasma membrane, although the details of this process remain poorly understood. Multivesicular body (MVB) proteins have been found to play a role in the budding of several enveloped viruses, including some paramyxoviruses, and the recruitment of MVB proteins by viral proteins possessing late budding domains (L-domains) has become an important concept in the viral budding process. Previously we developed a system for producing NiV virus-like particles (VLPs) and demonstrated that the matrix (M) protein possessed an intrinsic budding ability and played a major role in assembly. Here, we have used this system to further explore the budding process by analyzing elements within the M protein that are critical for particle release.
Results: Using rationally targeted site-directed mutagenesis we show that a NiV M sequence YPLGVG is required for M budding and that mutation or deletion of the sequence abrogates budding ability. Replacement of the native and overlapping Ebola VP40 L-domains with the NiV sequence failed to rescue VP40 budding; however, it did induce the cellular morphology of extensive filamentous projection consistent with wild-type VP40-expressing cells. Cells expressing wild-type NiV M also displayed this morphology, which was dependent on the YPLGVG sequence, and deletion of the sequence also resulted in nuclear localization of M. Dominant-negative VPS4 proteins had no effect on NiV M budding, suggesting that unlike other viruses such as Ebola, NiV M accomplishes budding independent of MVB cellular proteins.
Conclusion: These data indicate that the YPLGVG motif within the NiV M protein plays an important role in M budding; however, involvement of any specific components of the cellular MVB sorting pathway in henipavirus budding remains to be demonstrated. Further investigation of henipavirus assembly and budding may yet reveal a novel mechanism(s) of viral assembly and release that could be applicable to other enveloped viruses or have therapeutic implications.
C1 [Patch, Jared R.; Yan, Lianying; Broder, Christopher C.] Uniformed Serv Univ Hlth Sci, Dept Microbiol & Immunol, Bethesda, MD 20814 USA.
[Han, Ziying; McCarthy, Sarah E.; Harty, Ronald N.] Univ Penn, Sch Vet Med, Dept Pathobiol, Philadelphia, PA 19104 USA.
[Wang, Lin-Fa] CSIRO Livestock Ind, Australian Anim Hlth Lab, Geelong, Vic 3220, Australia.
[Patch, Jared R.] ARS, USDA, Plum Isl Anim Dis Ctr, Greenport, NY 11944 USA.
[Han, Ziying] Fox Chase Canc Ctr, Philadelphia, PA 19111 USA.
[McCarthy, Sarah E.] USA, Res Inst Infect Dis, Div Virol, Ft Detrick, MD 21702 USA.
RP Broder, CC (reprint author), Uniformed Serv Univ Hlth Sci, Dept Microbiol & Immunol, Bethesda, MD 20814 USA.
EM Jared.Patch@ARS.USDA.GOV; Ziying.Han@fccc.edu;
Sarah.E.Mccarthy@us.army.mil; lyan@usuhs.mil; Linfa.Wang@csiro.au;
rharty@vet.upenn.edu; cbroder@usuhs.mil
FU NIH [AI054715]
FX This work was supported by NIH grant AI054715 to C.C.B.
NR 57
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U1 1
U2 6
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1743-422X
J9 VIROL J
JI Virol. J.
PD NOV 10
PY 2008
VL 5
AR 137
DI 10.1186/1743-422X-5-137
PG 12
WC Virology
SC Virology
GA 395MN
UT WOS:000262528300001
PM 19000317
ER
PT J
AU Stebulis, JA
Johnson, DR
Rossetti, RG
Burstein, SH
Zurier, RB
AF Stebulis, Judith A.
Johnson, David R.
Rossetti, Ronald G.
Burstein, Sumner H.
Zurier, Robert B.
TI Ajulemic acid, a synthetic cannabinoid acid, induces an antiinflammatory
profile of eicosanoids in human synovial cells
SO LIFE SCIENCES
LA English
DT Article
DE Inflammation; Synovial cells; Prostaglandins; Cannabinoids;
Cyclooxygenase 2
ID ACTIVATED RECEPTOR-GAMMA; NITRIC-OXIDE SYNTHASE; PROSTAGLANDIN E-2
SYNTHASE-1; ARTHRITIS-LIKE DISEASE; 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN
J(2); RHEUMATOID-ARTHRITIS; PPAR-GAMMA; CYCLOPENTENONE PROSTAGLANDINS;
JOINT DESTRUCTION; GENE-EXPRESSION
AB Aims: To better understand mechanisms whereby Ajulemic acid (AjA), a synthetic antiinflammatory cannabinoid, promotes resolution of acute and chronic inflammation in animal models, we investigated its influence on cyclooxygenase 2 (COX2) expression and eicosanoid production in human fibroblast-like synovial cells (FLS).
Main methods: FLS isolated from tissue obtained at joint replacement surgery or cultured from synovial fluid were treated for 60 min with AjA (10-30 mu M), then stimulated with tumor necrosis factor alpha (TNF alpha). COX2 mRNA was measured by hybridization/colorimetric assay of whole cell lysates collected 4 h after Stimulation. To determine FLS were incubated with C-14-arachidonic acid for 20 h then treated with AjA (8-effects on arachidonic acid release, 32 mu M). Arachidonic acid release was measured by scintillation counting. Prostaglandins (PC) were measured by enzyme linked immunosorbent assay (ELISA) in cell supernatants collected 4 and 24 h after stimulation.
Key findings: AjA increased the steady state levels of COX2 mRNA in and arachidonic acid release from FLS. Treatment of FLS with AjA increased 15-deoxy-delta(12,14)-PGJ(2) (15d-PGJ(2)) production in a concentration dependent manner, but did not affect PGE(2) production significantly.
Significance: The capacity of AjA to increase selectively and markedly 15d-PGJ2, all eicosanoid which facilitates resolution of inflammation, suggests that AjA may have value as a therapeutic agent for the treatment of rheumatoid arthritis (RA) and other diseases characterized by acute and chronic inflammation. (C) 2008 Elsevier Inc. All rights reserved.
C1 [Stebulis, Judith A.] UMass Mem Med Ctr, Div Rheumatol, Worcester, MA 01605 USA.
[Rossetti, Ronald G.; Burstein, Sumner H.; Zurier, Robert B.] Univ Massachusetts, Sch Med, Worcester, MA 01655 USA.
[Johnson, David R.] USA, Engn Res & Dev Ctr, Environm Lab, Vicksburg, MS 39180 USA.
RP Stebulis, JA (reprint author), UMass Mem Med Ctr, Div Rheumatol, 119 Belmont St, Worcester, MA 01605 USA.
EM judith.stebulis@umassmed.edu
FU NIH [T32 AR07572]; National Institute of Arthritis and Musculoskeletal
and Skin Diseases (NIAMS) US; National Center for Complementary and
Alternative Medicine (NCCAM) [R01 AT000309]; National Institute on Drug
Abuse (NIDA) [R01 DA13691]; NIAID [AI056362]
FX We gratefully acknowledge Ann Skulas and Francisco J. Atez for their
excellent technical assistance with FLS culture maintenance. This study
was supported by NIH grants T32 AR07572 from the National Institute of
Arthritis and Musculoskeletal and Skin Diseases (NIAMS) US, Trainee),
R01 AT000309 from the National Center for Complementary and Alternative
Medicine (NCCAM), R01 DA13691 from the National Institute on Drug Abuse
(NIDA), and AI056362 (NIAID). Its contents are solely the responsibility
of the authors and do not necessarily represent the official view of the
National Institutes of Health.
NR 52
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U1 0
U2 0
PU PERGAMON-ELSEVIER SCIENCE LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
SN 0024-3205
J9 LIFE SCI
JI Life Sci.
PD NOV 7
PY 2008
VL 83
IS 19-20
BP 666
EP 670
DI 10.1016/j.lfs.2008.09.004
PG 5
WC Medicine, Research & Experimental; Pharmacology & Pharmacy
SC Research & Experimental Medicine; Pharmacology & Pharmacy
GA 373EE
UT WOS:000260953000006
PM 18840450
ER
PT J
AU Fan, SA
Wu, F
Martiniuk, F
Hale, ML
Ellington, AD
Tchou-Wong, KM
AF Fan, Shaoan
Wu, Feng
Martiniuk, Frank
Hale, Martha L.
Ellington, Andrew D.
Tchou-Wong, Kam-Meng
TI Protective effects of anti-ricin A-chain RNA aptamer against ricin
toxicity
SO WORLD JOURNAL OF GASTROENTEROLOGY
LA English
DT Article
DE Ricin inhibitor; RNA aptamer; Luciferase assay
ID RIBOSOME-INACTIVATING PROTEINS; IN-VITRO; TOXINS; MODEL; INHIBITION;
ANTIBODIES; MECHANISM; ASSAY
AB AIM: To investigate the therapeutic potential of an RNA ligand (aptamer) specific for the catalytic ricin A-chain (RTA), the protective effects of a 31-nucleotide RNA aptamer (31RA), which formed a high affinity complex with RTA, against ricin-induced toxicity in cell-based luciferase translation and cell cytotoxicity assays were evaluated.
METHODS: To test the therapeutic potential of anti-RTA aptamers in Chinese hamster ovary (CHO) AA8 cells stably transfected with a tetracycline regulatable promoter, ricin ribotoxicity was measured using luciferase and ricin-induced cytotoxicity was ascertained by MTS cell proliferation assay with tetrazolium compound [3-(4,5-dimethylthiazol-2-yl)5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H- tetrazolium].
RESULTS: Inhibition of protein synthesis by ricin in CHO AA8 cells resulted in diminished luciferase activity and treatment with polyclonal antibody against degly-cosylated RTA (dgA) neutralized the inhibitory effects of ricin on luciferase activity and protected against ricin-induced cytotoxicity as measured by MTS assay. The 31RA anti-RTA aptamer inhibited the translation of luciferase mRNA in cell-free reticulocyte translation assay. 31RA aptamer also partially neutralized the inhibitory effects of ricin on luciferase activity and partially protected against ricin-induced cytotoxicity in CHO AA8 cells.
CONCLUSION: We have shown that anti-RTA RNA aptamer can protect against ricin ribotoxicity in cell-based luciferase and cell cytotoxicity assays. Hence, RNA aptamer that inhibits RTA enzymatic activity represents a novel class of nucleic acid inhibitor that has the potential to be developed as a therapeutic agent for the treatment of ricin intoxication. (C) 2008 The WJG Press. All rights reserved.
C1 [Fan, Shaoan; Wu, Feng; Tchou-Wong, Kam-Meng] NYU, Sch Med, Dept Environm Med, Tuxedo Pk, NY 10987 USA.
[Martiniuk, Frank] NYU, Sch Med, Dept Med, New York, NY 10016 USA.
[Hale, Martha L.] USA, Med Res Inst Infect Dis, Integrated Toxicol Div, Ft Detrick, MD 21702 USA.
[Ellington, Andrew D.] Univ Texas Austin, Dept Chem & Biochem, Austin, TX 78712 USA.
RP Tchou-Wong, KM (reprint author), NYU, Sch Med, Dept Environm Med, 57 Old Forge Rd, Tuxedo Pk, NY 10987 USA.
EM tchouk02@nyumc.org
FU National Institutes of Health (Tchou-Wong) [ES-000260, AI-059476]
FX Grant from the National Institutes of Health (Tchou-Wong), No. ES-000260
and No. AI-059476
NR 20
TC 7
Z9 9
U1 1
U2 12
PU W J G PRESS
PI BEIJING
PA APT 1066, YISHOU GARDEN, NO 58, NORTH LANGXINZHUANG RD, PO BOX 2345,
BEIJING 100023, PEOPLES R CHINA
SN 1007-9327
J9 WORLD J GASTROENTERO
JI World J. Gastroenterol.
PD NOV 7
PY 2008
VL 14
IS 41
BP 6360
EP 6365
DI 10.3748/wjg.14.6360
PG 6
WC Gastroenterology & Hepatology
SC Gastroenterology & Hepatology
GA 374PX
UT WOS:000261057300016
PM 19009652
ER
PT J
AU Alvarez-Aviles, L
Simpson, WR
Douglas, TA
Sturm, M
Perovich, D
Domine, F
AF Alvarez-Aviles, Laura
Simpson, William R.
Douglas, Thomas A.
Sturm, Matthew
Perovich, Donald
Domine, Florent
TI Frost flower chemical composition during growth and its implications for
aerosol production and bromine activation
SO JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES
LA English
DT Article
ID LAYER OZONE DEPLETION; SEA-SALT AEROSOL; POLAR SUNRISE; ICE; SNOW;
SURFACE; REGIONS; TEMPERATURE
AB Frost flowers have been proposed to be the major source of sea-salt aerosol to the atmosphere during polar winter and a source of reactive bromine during polar springtime. However little is known about their bulk chemical composition or microstructure, two important factors that may affect their ability to produce aerosols and provide chemically reactive surfaces for exchange with the atmosphere. Therefore, we chemically analyzed 28 samples of frost flowers and parts of frost flowers collected from sea ice off of northern Alaska. Our results support the proposed mechanism for frost flower growth that suggests water vapor deposition forms an ice skeleton that wicks brine present on newly grown sea ice. We measured a high variability in sulfate enrichment factors (with respect to chloride) in frost flowers and seawater from the vicinity of freezing sea ice. The variability in sulfate indicates that mirabilite precipitation (Na2SO4 center dot 10 H2O) occurs during frost flower growth. Brine wicked up by frost flowers is typically sulfate depleted, in agreement with the theory that frost flowers are related to sulfate-depleted aerosol observed in Antarctica. The bromide enrichment factors we measured in frost flowers are within error of seawater composition, constraining the direct reactive losses of bromide from frost flowers. We combined the chemical composition measurements with temperature observations to create a conceptual model of possible scenarios for frost flower microstructure development.
C1 [Alvarez-Aviles, Laura; Simpson, William R.] Univ Alaska Fairbanks, Inst Geophys, Fairbanks, AK 99775 USA.
[Alvarez-Aviles, Laura; Simpson, William R.] Univ Alaska Fairbanks, Dept Chem & Biochem, Fairbanks, AK 99775 USA.
[Domine, Florent] CNRS, Lab Glaciol & Geophys Environm, F-38402 St Martin Dheres, France.
[Domine, Florent] Univ Grenoble 1, F-38402 St Martin Dheres, France.
[Douglas, Thomas A.; Sturm, Matthew] USA, Cold Reg Res & Engn Lab, Ft Wainwright, AK 99703 USA.
[Perovich, Donald] USA, Cold Reg Res & Engn Lab, Hanover, NH 03755 USA.
RP Alvarez-Aviles, L (reprint author), Univ Alaska Fairbanks, Inst Geophys, 900 Yukon Dr,Room 186, Fairbanks, AK 99775 USA.
EM ffwrs@uaf.edu
RI Domine, Florent/E-8699-2011; Simpson, William/I-2859-2014
OI Simpson, William/0000-0002-8596-7290
NR 39
TC 33
Z9 34
U1 0
U2 13
PU AMER GEOPHYSICAL UNION
PI WASHINGTON
PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 USA
SN 2169-897X
J9 J GEOPHYS RES-ATMOS
JI J. Geophys. Res.-Atmos.
PD NOV 5
PY 2008
VL 113
IS D21
AR D21304
DI 10.1029/2008JD010277
PG 10
WC Meteorology & Atmospheric Sciences
SC Meteorology & Atmospheric Sciences
GA 370UL
UT WOS:000260788500010
ER
PT J
AU Yu, L
Putnak, JR
Pletnev, AG
Markoff, L
AF Yu, Li
Putnak, J. Robert
Pletnev, Alexander G.
Markoff, Lewis
TI Attenuated West Nile viruses bearing 3 ' SL and envelope gene
substitution mutations
SO VACCINE
LA English
DT Article
DE Live West Nile vaccine; Flavivirus 3 ' SL mutation; Attenuation of
neurovirulence
ID JAPANESE ENCEPHALITIS-VIRUS; CD8(+) T-CELLS; LETHAL CHALLENGE;
MOLECULAR-BASIS; UNITED-STATES; NY99 STRAIN; GENOMIC RNA; VACCINE;
FLAVIVIRUS; NEUROVIRULENCE
AB Four viable West Nile (WN) 3'SL-mutant Viruses were evaluated for neuroinvasiveness and neurovirulence in mice. All mutants were highly attenuated for neuroinvasiveness. However, only one of these four (WNmutE virus) was significantly attenuated for neurovirulence. To attenuate WNmutE virus further, we introduced five substitution mutations into the envelope (env) gene segment in wild-type (wt) WN and WNmutE genomes, based on differences in the env gene Sequence between the live Japanese encephalitis vaccine (SA14-14-2) and its virulent parent. The env gene mutations had an attenuating effect in the context of the wt WNV genome but only a Marginal enhancing effect on the attenuation of WNmutE virus. Published by Elsevier Ltd.
C1 [Yu, Li; Markoff, Lewis] US FDA, Div Viral Prod, Lab Vector Borne Virus Dis, Bethesda, MD 20892 USA.
[Putnak, J. Robert] Walter Reed Army Inst Res, Div Communicable Dis & Immunol, Silver Spring, MD 20910 USA.
[Pletnev, Alexander G.] NIAID, Infect Dis Lab, NIH, Bethesda, MD 20892 USA.
RP Yu, L (reprint author), Bg 29A,Room 1B18,NIH Campus,8800 Rockville Pike, Bethesda, MD 20892 USA.
EM Li.Yu@fda.hhs.gov
FU National Vaccine Program
FX The authors thank Dr. V. Yamshchikov for the gift of the West Nile Virus
strain B956 infectious DNA. This work was partially supported by a grant
from the National Vaccine Program.
NR 36
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U1 0
U2 0
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0264-410X
J9 VACCINE
JI Vaccine
PD NOV 5
PY 2008
VL 26
IS 47
BP 5981
EP 5988
DI 10.1016/j.vaccine.2008.08.064
PG 8
WC Immunology; Medicine, Research & Experimental
SC Immunology; Research & Experimental Medicine
GA 384MZ
UT WOS:000261750200014
PM 18805457
ER
PT J
AU Li, QG
Xie, LS
Zhang, J
Weina, PJ
AF Li, Qigui
Xie, Lisa
Zhang, Jing
Weina, Peter J.
TI The distribution pattern of intravenous [C-14] artesunate in rat tissues
by quantitative whole-body autoradiography and tissue dissection
techniques
SO JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
LA English
DT Article
DE [C-14] Artesunate; Dihydroartemisinin; QWBA; LSC; Tissue distribution;
Pharmacokinetics; Rats
ID ENTEROHEPATIC CIRCULATION; BILIARY-EXCRETION; RADIOLUMINOGRAPHY;
PHARMACOKINETICS; METABOLISM; ARTELINATE; ANIMALS
AB Quantitative whole-body autoradiography (QWBA) and liquid scintillation counting (LSC) have been conducted to determine the metabolic profiles and tissue distribution of [C-14] labeled artesunate (AS) injection in rats. The QWBA technique showed more accurate results in the quantification of radioactivity in 40 organs and tissues, compared to 19 organs with the LSC technique. The benefit of QWBA was especially apparent on measurements of bile, bone marrow, and gland organs; however, the LSC method produced more relevant findings than QWBA. Particularly, the LSC method allowed access to the following distribution patterns that were unavailable via QWBA performance: such as pharmacokinetic evaluation of radiolabeled AS in blood and plasma, tissue/plasma partition coefficients, conversion pathway of AS to dihydroartemisinin (DHA, an active and major metabolite of AS), unchanged AS and DHA in plasma, mass balance assessment, urinary and faecal eliminations, drug pathway with conjugation, [14C] AS binding with RBC and plasma protein, and metabolites identification. Even though the each method has its own advantages, common profiles were obtained from the two processes as shown in the results of the biliary metabolism, long-lasting metabolites, tissue distribution profiles, and multiple concentration peaks, which indicate a [C-14] AS enterohepatic circulation. (c) 2008 Elsevier B.V. All rights reserved.
C1 [Li, Qigui; Xie, Lisa; Zhang, Jing; Weina, Peter J.] Walter Reed Army Med Ctr, Walter Reed Army Inst Res, Div Expt Therapeut, Dept Pharmacol, Silver Spring, MD 20307 USA.
RP Li, QG (reprint author), Walter Reed Army Med Ctr, Walter Reed Army Inst Res, Div Expt Therapeut, Dept Pharmacol, 503 Robert Grant Ave, Silver Spring, MD 20307 USA.
EM qigui.li@amedd.army.mil
RI Weina, Peter/A-2120-2011
FU United States Army Research and Materiel Command
FX This study was supported by the United States Army Research and Materiel
Command. The opinions or assertions contained herein are the private
views of the author and are not to be construed as official, or as
reflecting true views of the Department of the Army or the Department of
Defense.
NR 33
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U1 0
U2 7
PU PERGAMON-ELSEVIER SCIENCE LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
SN 0731-7085
J9 J PHARMACEUT BIOMED
JI J. Pharm. Biomed. Anal.
PD NOV 4
PY 2008
VL 48
IS 3
BP 876
EP 884
DI 10.1016/j.jpba.2008.07.015
PG 9
WC Chemistry, Analytical; Pharmacology & Pharmacy
SC Chemistry; Pharmacology & Pharmacy
GA 362KL
UT WOS:000260196500052
PM 18762400
ER
PT J
AU Parthasarathy, N
Saksena, R
Kovac, P
DeShazer, D
Peacock, SJ
Wuthiekanun, V
Heine, HS
Friedlander, AM
Cote, CK
Welkos, SL
Adamovicz, JJ
Bavari, S
Waag, DM
AF Parthasarathy, N.
Saksena, R.
Kovac, P.
DeShazer, D.
Peacock, S. J.
Wuthiekanun, V.
Heine, H. S.
Friedlander, A. M.
Cote, C. K.
Welkos, S. L.
Adamovicz, J. J.
Bavari, S.
Waag, D. M.
TI Application of carbohydrate microarray technology for the detection of
Burkholderia pseudomallei, Bacillus anthracis and Francisella tularensis
antibodies
SO CARBOHYDRATE RESEARCH
LA English
DT Article
DE Carbohydrate microarray; Burkholderia pseudomallei (melioidosis);
Bacillus anthracis (anthrax); Francisella tularensis (tularemia); Serum
antibodies
ID GLYCAN ARRAYS; O-ANTIGEN; EXOSPORIUM; LIPOPOLYSACCHARIDE; MELIOIDOSIS;
BCLA; OLIGOSACCHARIDE; GLYCOMICS; IDENTIFICATION; GLYCOPROTEIN
AB We developed a microarray platform by immobilizing bacterial 'signature' carbohydrates onto epoxide modified glass slides. The carbohydrate microarray platform was probed with sera from non-melioidosis and melioidosis (Burkholderia pseudomallei) individuals. The platform was also probed with sera from rabbits vaccinated with Bacillus anthracis spores and Francisella tularensis bacteria. By employing this microarray platform, we were able to detect and differentiate B. pseudomallei, B. anthracis and F. tularensis antibodies in infected patients, and infected or vaccinated animals. These antibodies were absent in the sera of naive test subjects. The advantages of the carbohydrate microarray technology over the traditional indirect hemagglutination and microagglutination tests for the serodiagnosis of melioidosis and tularemia are discussed. Furthermore, this array is a multiplex carbohydrate microarray for the detection of all three biothreat bacterial infections including melioidosis, anthrax and tularemia with one, multivalent device. The implication is that this technology could be expanded to include a wide array of infectious and biothreat agents. (C) 2008 Elsevier Ltd. All rights reserved.
C1 [Parthasarathy, N.; DeShazer, D.; Heine, H. S.; Cote, C. K.; Welkos, S. L.; Adamovicz, J. J.; Bavari, S.; Waag, D. M.] USA, Med Res Inst Infect Dis, Bacteriol Div, Frederick, MD 21702 USA.
[Saksena, R.; Kovac, P.] NIDDK, LBC, NIH, Bethesda, MD 20892 USA.
[Peacock, S. J.; Wuthiekanun, V.] Mahidol Univ, Fac Trop Med, Mahidol Oxford Trop Med Res Unit, Bangkok, Thailand.
RP Parthasarathy, N (reprint author), USA, Med Res Inst Infect Dis, Bacteriol Div, Frederick, MD 21702 USA.
EM Narayanan.Parthasarathy@us.army.mil
FU US Army Medical Research and Materiel Command [2.10018_06 _RD-B,
2.10019_07_RD-B, 5.10023_08_RD-B]; Welcome Trust Career Development
fellowship in Clinical Tropical Medicine; Human Use Committee [FY 06-36,
HP-06-36]
FX The research described herein was sponsored by the US Army Medical
Research and Materiel Command under projects 2.10018_06 _RD-B,
2.10019_07_RD-B and 5.10023_08_RD-B. The authors thank Sarah L. Norris
for statistical analysis. The authors also thank Dr. Sharan VedBrat
(KamTek Inc., Gaithersburg, MD) for carbohydrate printing. The support
of staff at Sappasithiprasong Hospital, Ubon Ratchathani, and the
Mahidol Oxford Tropical Medicine Research Unit, particularly Dr. Direk
Limmathurotsakul and Dr. Allen Chang, is gratefully acknowledged. S.P.
is funded by a Welcome Trust Career Development fellowship in Clinical
Tropical Medicine. The use of human serum samples was approved by the
Human Use Committee (FY 06-36, HP-06-36). Research was conducted in
compliance with the Animal Welfare Act and other federal statutes and
regulations relating to animals and experiments involving animals and
adheres to principles stated in the Guide for the Care and Use of
Laboratory Animals, National Research Council, 1996. The facility where
this research was conducted is fully accredited by the Association for
Assessment and Accreditation of Laboratory Animal Care International.
Opinions, interpretations, conclusions and recommendations are those of
the authors and not endorsed by the US Army.
NR 38
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U1 1
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PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0008-6215
J9 CARBOHYD RES
JI Carbohydr. Res.
PD NOV 3
PY 2008
VL 343
IS 16
BP 2783
EP 2788
DI 10.1016/j.carres.2008.05.021
PG 6
WC Biochemistry & Molecular Biology; Chemistry, Applied; Chemistry, Organic
SC Biochemistry & Molecular Biology; Chemistry
GA 370AU
UT WOS:000260735900010
PM 18558401
ER
PT J
AU Peterson, JA
AF Peterson, James A.
TI Ten Common Mistakes Individuals Who Are Trying to Lose Weight Make
SO ACSMS HEALTH & FITNESS JOURNAL
LA English
DT Editorial Material
C1 [Peterson, James A.] US Mil Acad, West Point, NY 10996 USA.
NR 0
TC 0
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U1 0
U2 0
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 1091-5397
J9 ACSMS HEALTH FIT J
JI ACSMS Health Fit. J.
PD NOV-DEC
PY 2008
VL 12
IS 6
BP 52
EP 52
PG 1
WC Sport Sciences
SC Sport Sciences
GA 372FJ
UT WOS:000260887200012
ER
PT J
AU Signore, C
Aros, S
Morrow, JD
Troendle, J
Conley, MR
Flanigan, EY
Cassorla, F
Mills, JL
AF Signore, Caroline
Aros, Sofia
Morrow, Jason D.
Troendle, James
Conley, Mary R.
Flanigan, Elizabeth Y.
Cassorla, Fernando
Mills, James L.
TI Markers of Oxidative Stress and Systemic Vasoconstriction in Pregnant
Women Drinking >= 48 g of Alcohol per Day
SO ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
LA English
DT Article
DE Alcohol; Pregnancy; Isoprostanes; Prostacyclin; Thromboxane; Fetal
Alcohol Spectrum Disorders
ID CHROMATOGRAPHY MASS-SPECTROMETRY; LIPID-PEROXIDATION; OXIDANT STRESS;
IN-VIVO; 8-ISO-PROSTAGLANDIN F2-ALPHA; MATERNAL THROMBOXANE; BIOACTIVE
PRODUCTS; BIOLOGICAL-FLUIDS; HUMAN PLACENTA; BLOOD-FLOW
AB Background: The precise pathway by which alcohol causes the characteristic features of fetal alcohol spectrum disorders is unknown. Proposed mechanisms for fetal injury from maternal alcohol use include cellular damage from oxidative stress and impaired fetal oxygenation related to maternal systemic vasoconstriction. Our objective was to compare the levels of urinary markers of oxidative stress and systemic vasoconstriction between women consuming large amounts of alcohol during pregnancy and women who did not drink alcohol during pregnancy. Methods: Pregnant women consuming >= 48 g alcohol per day (n = 29) on average and pregnant women who abstained from alcohol use (n = 39) were identified using detailed interviews and home visits. Random maternal urine specimens were collected. Urinary levels of the oxidative stress marker, 8-isoprostane F2 alpha, and of the vasoactive prostaglandin metabolites, 2,3-dinor-6-keto-prostaglandin F1 alpha (a vasodilator) and 11-dehydro-thromboxane B2 (a vasoconstrictor), were measured using mass spectrometric methods. All analyte levels were corrected for urinary creatinine.
Results: In crude analyses, there was no significant difference in 8-isoprostane F2 alpha between pregnant drinkers and nondrinkers (2.16 vs. 2.08 ng/mg creatinine, respectively, p = 0.87). There were no significant differences between the drinking and nondrinking groups in levels of 2,3-dinor-6-keto-prostaglandin F1 alpha (1.03 vs. 1.17 ng/mg creatinine, repectively, p = 0.50), 11-dehydro-thromboxane B2 (0.72 vs. 0.59 ng/mg creatinine, respectively, p = 0.21), or the ratio of vasodilatory metabolite to vasoconstrictive metabolite (1.73 vs. 2.72, respectively, p = 0.14). Adjusting for maternal age, marital status, smoking, and gestational age at sampling did not substantially alter the results.
Conclusion: Our results show no difference in levels of urinary eicosanoid markers of oxidative stress and systemic vasoconstriction between pregnant women who drink heavily and pregnant women who abstain. These findings speak against a role for maternal oxidative stress or systemic vasoconstriction in the pathogenesis of alcohol damage to the fetus.
C1 [Mills, James L.] NICHD, Epidemiol Branch, Div Epidemiol Stat & Prevent Res,NIH,US Dept Hlth, Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Bethesda, MD 20892 USA.
[Aros, Sofia] Univ Chile, San Borja Arriaran Clin Hosp, Sch Med, Dept Pediat, Santiago, Chile.
[Morrow, Jason D.] Vanderbilt Univ, Sch Med, Div Clin Pharmacol, Dept Med, Nashville, TN 37212 USA.
[Morrow, Jason D.] Vanderbilt Univ, Sch Med, Div Clin Pharmacol, Dept Pharmacol, Nashville, TN 37212 USA.
[Troendle, James] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Biometry & Math Stat Branch, Div Epidemiol Stat & Prevent Res, NIH,US Dept Hlth & Human Serv, Bethesda, MD USA.
[Flanigan, Elizabeth Y.] Uniformed Serv Univ Hlth Sci, Dept Pediat, Washington, DC USA.
[Flanigan, Elizabeth Y.] Walter Reed Army Med Ctr, Washington, DC 20307 USA.
[Cassorla, Fernando] Univ Chile, Inst Maternal & Child Res, Dept Pediat, Div Pediat Endocrinol, Santiago, Chile.
RP Mills, JL (reprint author), NICHD, Epidemiol Branch, Div Epidemiol Stat & Prevent Res,NIH,US Dept Hlth, Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Bethesda, MD 20892 USA.
EM MillsJ@mail.nih.gov
FU Eunice Kennedy Shriver National Institute of Child Health and Human
Development; National Institutes of Health [GM15431, DK48831, ES13125]
FX This research was supported by the Intramural Research Program of the
Eunice Kennedy Shriver National Institute of Child Health and Human
Development and by National Institutes of Health grants GM15431, DK48831
and ES13125.
NR 47
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U1 2
U2 6
PU BLACKWELL PUBLISHING
PI OXFORD
PA 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND
SN 0145-6008
J9 ALCOHOL CLIN EXP RES
JI Alcoholism (NY)
PD NOV
PY 2008
VL 32
IS 11
BP 1893
EP 1898
DI 10.1111/j.1530-0277.2008.00773.x
PG 6
WC Substance Abuse
SC Substance Abuse
GA 362FK
UT WOS:000260183400005
PM 18715278
ER
PT J
AU Hoge, CW
AF Hoge, Charles W.
TI RE: "PSYCHIATRIC DIAGNOSES IN HISTORIC AND CONTEMPORARY MILITARY
COHORTS: COMBAT DEPLOYMENT AND THE HEALTHY WARRIOR EFFECT
SO AMERICAN JOURNAL OF EPIDEMIOLOGY
LA English
DT Letter
ID POSTTRAUMATIC-STRESS-DISORDER; IRAQ; AFGHANISTAN; WAR
C1 Walter Reed Army Inst Res, Div Psychiat & Neurosci, Silver Spring, MD 20910 USA.
RP Hoge, CW (reprint author), Walter Reed Army Inst Res, Div Psychiat & Neurosci, Silver Spring, MD 20910 USA.
EM charles.hoge@us.army.mil
NR 9
TC 10
Z9 10
U1 0
U2 0
PU OXFORD UNIV PRESS INC
PI CARY
PA JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
SN 0002-9262
J9 AM J EPIDEMIOL
JI Am. J. Epidemiol.
PD NOV 1
PY 2008
VL 168
IS 9
BP 1095
EP U12
DI 10.1093/aje/kwn261
PG 2
WC Public, Environmental & Occupational Health
SC Public, Environmental & Occupational Health
GA 365BM
UT WOS:000260380900021
PM 18775923
ER
PT J
AU Van Uitert, RL
Summers, RM
White, JM
Deshpande, KK
Choi, JR
Pickhardt, PJ
AF Van Uitert, Robert L.
Summers, Ronald M.
White, Jacob M.
Deshpande, Keshav K.
Choi, J. Richard
Pickhardt, Perry J.
TI Temporal and Multiinstitutional Quality Assessment of CT Colonography
SO AMERICAN JOURNAL OF ROENTGENOLOGY
LA English
DT Article
DE colon; colonography; CT; quality; virtual colonoscopy
ID COMPUTED TOMOGRAPHIC COLONOGRAPHY; OPTIMIZING COLONIC DISTENSION;
COLORECTAL NEOPLASIA; VIRTUAL COLONOSCOPY; CARBON-DIOXIDE; RESIDUAL
FLUID; INSUFFLATION; VALIDATION; EXPERIENCE
AB OBJECTIVE. The purpose of this study was to investigate the variability of CT colonography (CTC) scan quality obtained within and between institutions by using previously validated automated quality assessment (QA) software that assesses colonic distention and surface area obscured by residual fluid.
MATERIALS AND METHODS. The CTC scans of 120 patients were retrospectively selected, 30 from each of four institutions. The bowel preparation included oral contrast material for fecal and fluid tagging. Patients at one institution (institution 4) drank half the amount of oral contrast material compared with the patients at the other three institutions. Fifteen of the CTC scans were from the beginning of the protocol studied at each institution and 15 scans were from the same protocol acquired approximately 1 year later in the study. We used previously validated QA software to automatically measure the mean distention and residual fluid of each of five colonic segments (ascending, transverse, descending, sigmoid, and rectum). Adequate distention was defined as a colonic diameter of at least 2 cm. Residual fluid was determined by the percentage of colonic surface area covered by fluid. We compared how the quality varied across multiple institutions and over time within the same institution.
RESULTS. No significant difference in the amount of colonic distention among the four institutions was found (p = 0.19). However, the distention in the prone position was significantly greater than the distention in the supine position (p < 0.001). Patients at institution 4 had about half the amount of residual colonic fluid compared with patients at the other three institutions (p < 0.01). The sigmoid and descending colons were the least distended segments, and the transverse and descending colons contained the most fluid on the prone and supine scans, respectively. More recently acquired studies had greater distention and less residual fluid, but the differences were not statistically significant (p = 0.30 and p = 0.96, respectively).
CONCLUSION. Across institutions, a significant difference can exist in bowel preparation quality for CTC. This study reaffirms the need for standardized bowel preparation and quality monitoring of CTC examinations to reduce poor CTC performance.
C1 [Van Uitert, Robert L.; Summers, Ronald M.; White, Jacob M.; Deshpande, Keshav K.] Natl Inst Hlth Clin Ctr, Bethesda, MD 20892 USA.
[Choi, J. Richard] Walter Reed Army Med Ctr, Dept Radiol, Washington, DC 20307 USA.
[Choi, J. Richard] Uniformed Serv Univ Hlth Sci, Dept Radiol, Bethesda, MD 20814 USA.
[Pickhardt, Perry J.] Univ Wisconsin, Sch Med, Dept Radiol, Madison, WI USA.
RP Summers, RM (reprint author), Natl Inst Hlth Clin Ctr, Bldg 10,Rm 1C368X MSC 1182, Bethesda, MD 20892 USA.
EM rms@nih.gov
FU National Institutes of Health Clinical Center
FX This study was supported by the Intramural Research Program of the
National Institutes of Health Clinical Center.
NR 25
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U1 0
U2 1
PU AMER ROENTGEN RAY SOC
PI RESTON
PA 1891 PRESTON WHITE DR, SUBSCRIPTION FULFILLMENT, RESTON, VA 22091 USA
SN 0361-803X
EI 1546-3141
J9 AM J ROENTGENOL
JI Am. J. Roentgenol.
PD NOV
PY 2008
VL 191
IS 5
BP 1503
EP 1508
DI 10.2214/AJR.07.3591
PG 6
WC Radiology, Nuclear Medicine & Medical Imaging
SC Radiology, Nuclear Medicine & Medical Imaging
GA 363DQ
UT WOS:000260246700034
PM 18941092
ER
PT J
AU Tyler, JA
McDermott, D
Levoyer, T
AF Tyler, Joshua A.
McDermott, Dustin
Levoyer, Thomas
TI Sterile Intra-Abdominal Fluid Collection Associated with Seprafilm Use
SO AMERICAN SURGEON
LA English
DT Article
ID ADHESIONS; SURGERY; COMPLICATION; PREVENTION; EFFICACY; BARRIER; SAFETY
AB Postoperative abdominal adhesions are a significant cause of morbidity and expenditure of healthcare resources. As a result, numerous substances have been studied in an effort to reduce the incidence of adhesive disease. Seprafilm, a hyaluronate-based bioresorbable membrane, has been the subject of considerable research and has been found to be both safe and effective in reducing postoperative adhesions. We report three cases of the development of sterile abdominal fluid collection after the use of Seprafilm in colorectal surgery.
C1 [Tyler, Joshua A.] Brooke Army Med Ctr, ATTN MCHE SDG, Dept Gen Surg, Ft Sam Houston, TX 78234 USA.
RP Tyler, JA (reprint author), Brooke Army Med Ctr, ATTN MCHE SDG, Dept Gen Surg, 3851 Roger Brooke Dr, Ft Sam Houston, TX 78234 USA.
EM Josh.Tyler@amedd.army.mil
NR 17
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Z9 5
U1 0
U2 0
PU SOUTHEASTERN SURGICAL CONGRESS
PI ATLANTA
PA 141 WEST WIEUCA RD, STE B100, ATLANTA, GA 30342 USA
SN 0003-1348
J9 AM SURGEON
JI Am. Surg.
PD NOV
PY 2008
VL 74
IS 11
BP 1107
EP 1110
PG 4
WC Surgery
SC Surgery
GA 373WX
UT WOS:000261005300014
PM 19062671
ER
PT J
AU Haymore, BR
Yoon, J
Mikita, CP
Klote, MM
DeZee, KJ
AF Haymore, Bret R.
Yoon, Jiun
Mikita, Cecilia P.
Klote, Mary M.
DeZee, Kent J.
TI Risk of angioedema with angiotensin receptor blockers in patients with
prior angioedema associated with angiotensin-converting enzyme
inhibitors: a meta-analysis
SO ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
LA English
DT Article
ID ANTAGONISTS
AB Background: Patients who have angioedema after taking angiotensin-converting enzyme inhibitors (ACE-Is) have been reported to develop angioedema when taking an angiotensin receptor blocker (ARB), but few studies quantify the risk.
Objective: To perform a systematic review of the literature.
Methods: A literature search was performed in MEDLINE, EMBASE, BIOSIS, and Current Contents, with no limitations from January 1990 to May 2007. Any article that described a cohort of patients who had angioedema after taking an ACE-I, were subsequently exposed to an ARB, and were followed for a least I month were included. The percentage of patients who had angioedema was abstracted from each article, and confidence intervals were calculated using the exact binomial method. The pooled percentage was calculated with the inverse variance method.
Results: Two-hundred fifty-four unique articles were identified, and 3 articles met inclusion criteria, which described 71 patients with the outcome of interest. One was a randomized controlled trial and 2 were retrospective cohorts. These articles described both confirmed and possible cases of angioedema. The risk of angioedema was 9.4% (95% confidence interval, 1.6%-17%) for possible cases and 3.5% (95% confidence interval, 0.0%-9.2%) for confirmed cases. No fatal events were reported. No statistical heterogeneity was reported between trials (P >.3).
Conclusions: Limited evidence suggests that for patients who develop angioedema when taking an ACE-I, the risk of development of any subsequent angioedema when taking an ARB is between 2% and 17%; for confirmed angioedema, the risk is 0% to 9.2%. This information will aid clinicians in counseling patients regarding therapy options after development of angioedema due to ACE-Is.
C1 [Haymore, Bret R.; Yoon, Jiun; Mikita, Cecilia P.; Klote, Mary M.] Walter Reed Army Med Ctr, Dept Allergy Immunol, Washington, DC 20307 USA.
[DeZee, Kent J.] William Beaumont Army Med Ctr, Dept Internal Med, El Paso, TX 79920 USA.
RP Haymore, BR (reprint author), 5213 Flanders Ave, Kensington, MD 20895 USA.
EM bret.haymore@amedd.army.mil
NR 14
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U1 0
U2 1
PU AMER COLL ALLERGY ASTHMA IMMUNOLOGY
PI ARLINGTON HTS
PA 85 WEST ALGONQUIN RD SUITE 550, ARLINGTON HTS, IL 60005 USA
SN 1081-1206
J9 ANN ALLERG ASTHMA IM
JI Ann. Allergy Asthma Immunol.
PD NOV
PY 2008
VL 101
IS 5
BP 495
EP 499
PG 5
WC Allergy; Immunology
SC Allergy; Immunology
GA 369WY
UT WOS:000260725800009
PM 19055203
ER
PT J
AU Asplund, CA
Seehusen, DA
Callahan, TL
Olsen, C
AF Asplund, Chad A.
Seehusen, Dean A.
Callahan, Terra L.
Olsen, Cara
TI Percentage Change in Antenatal Body Mass Index as a Predictor of
Neonatal Macrosomia
SO ANNALS OF FAMILY MEDICINE
LA English
DT Article
DE Fetal macrosomia; body mass index; pregnancy
ID ESTIMATED FETAL WEIGHT; MATERNAL CHARACTERISTICS; BIRTH-WEIGHT; FETUS;
RISK; PREGNANCIES; MANAGEMENT; OUTCOMES
AB PURPOSE We wanted to evaluate the predictive value of percentage change in antenatal maternal body mass index (BMI) as it relates to macrosomia, as well as to compare change in pregnancy BMI with existing weight gain guidelines.
METHODS We analyzed data from 6 months of consecutive deliveries, focusing on first visit (first trimester) BMI, last visit (37 weeks or later) BMI, and fetal birth weight. Using regression and chi(2) analyses, we evaluated the relationship between change in BMI and macrosomia.
RESULTS Of the 238 consecutive deliveries, we were able to analyze data from 186, of which 15.6% (n = 29) of the infants were macrosomic. Among macrosomic infants, 86.2% (25/29) of their mothers had a 25% or greater increase in BMI compared with 6.6% (10/157) of mothers of normal-weight infants (P <.001), for a relative risk 13.5% (95% confidence interval [0], 7.3%-25.1%). Percentage change in BMI of 25% or greater had a sensitivity of 86.2% (95% Cl, 68.3%-96.1%), a specificity of 93.6% (95% Cl, 88.6%-96.9%), a positive predictive value of 71.4% (95% Cl, 53.7%-85.4%), and a negative predictive value 97.4% (95% Cl, 93.4%-99.3%) for macrosomia. Logistic regression adjusted for maternal age, race, parity, and gravidity showed that those women whose BMI increased 25% or greater were more than 200 times more likely (odds ratio [OR] = 219.3; 95% Cl, 38.8-1,238.6; P <.001) to give birth to a macrosomic infant. Further adjusting for initial BMI strengthened the association (OR = 1,062.4; 95% Cl, 83.2-13,572.2; P < 001). Regardless of weight gain, when compared with Institute of Medicine weight gain recommendations, change in BMI or 25% or greater was associated with macrosomia (P <.001).
CONCLUSION Independent of initial pregnancy BMI or absolute weight gain, an increase in maternal BMI of 25% or greater during pregnancy is highly predictive of macrosomia. Ann Fam Med 2008:6;550-554. DOI: 10.1370/afm.903.
C1 [Asplund, Chad A.; Seehusen, Dean A.; Callahan, Terra L.] Eisenhower Army Med Ctr, Dept Family Med, Ft Gordon, GA 30905 USA.
[Olsen, Cara] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA.
RP Asplund, CA (reprint author), Eisenhower Army Med Ctr, Dept Family Med, Ft Gordon, GA 30905 USA.
EM chad.asplund@osumc.edu
NR 20
TC 14
Z9 14
U1 0
U2 1
PU ANNALS FAMILY MEDICINE
PI LEAWOOD
PA 11400 TOMAHAWK CREEK PARKWAY, LEAWOOD, KS 66211-2672 USA
SN 1544-1709
J9 ANN FAM MED
JI Ann. Fam. Med.
PD NOV-DEC
PY 2008
VL 6
IS 6
BP 550
EP 554
DI 10.1370/afm.903
PG 5
WC Medicine, General & Internal
SC General & Internal Medicine
GA 374GJ
UT WOS:000261031500012
PM 19001308
ER
PT J
AU Shanti, RM
Janjanin, S
Li, WJ
Nesti, LJ
Mueller, MB
Tzeng, MB
Tuan, RS
AF Shanti, Rabie M.
Janjanin, Sasa
Li, Wan-Ju
Nesti, Leon J.
Mueller, Michael B.
Tzeng, Megan B.
Tuan, Rocky S.
TI In Vitro Adipose Tissue Engineering Using an Electrospun Nanofibrous
Scaffold
SO ANNALS OF PLASTIC SURGERY
LA English
DT Article
DE adipose tissue engineering; electrospinning; nanofibers; mesechymal stem
cells; tissue engineering
ID MESENCHYMAL STEM-CELLS; COLLAGEN IMPLANT; AUGMENTATION; VIVO;
PREADIPOCYTES; MATRIX; DIFFERENTIATION; TRANSPLANTATION; PROLIFERATION;
LIPOSUCTION
AB Electrospun 3-dimensional nanofibrous scaffolds share morphologic similarities to collagen fibrils, and promote favorable biologic responses of seeded cells. In this Study, we have fabricated a 3-dimensional nanofibrous scaffold made of poly L-lactic acid, and examined its ability to support and maintain the adipogenic differentiation of human bone marrow-derived mesenchymal stem cells in vitro. After a 21-day incubation, on red O staining of constructs treated with adipogenic supplements revealed positive adipose-like staining, compared with lack of staining in untreated cultures. Semi-quantitative RT-PCR analysis of human bone marrow-derived mesenchymal stern Cells Cultured in adipogenic medium revealed highly elevated levels of adipogenesis-associated genes (1797-fold for lipoprotein lipase, and 5.6-fold for peroxisome proliferator-activated receptor gamma). Immunofluorescence staining of cellular constructs in adipogenic culture media showed the presence of lipoprotein lipase vesicles, a characteristic feature of adipose tissue. These results suggest that the poly L-lactic acid-based nanofibrous scaffold is a promising candidate for adult stern cell-based engineering of adipose tissue.
C1 [Shanti, Rabie M.; Janjanin, Sasa; Li, Wan-Ju; Mueller, Michael B.; Tzeng, Megan B.; Tuan, Rocky S.] NIAMSD, Dept Hlth & Human Serv, Cartilage Biol & Orthopaed Branch, NIH, Bethesda, MD 20892 USA.
[Shanti, Rabie M.] NIH, Howard Hughes Med Inst, Res Scholars Program, Bethesda, MD 20892 USA.
[Nesti, Leon J.] Walter Reed Army Med Ctr, Dept Orthopaed & Rehabil, Washington, DC 20307 USA.
RP Tuan, RS (reprint author), NIAMSD, Dept Hlth & Human Serv, Cartilage Biol & Orthopaed Branch, NIH, Bldg 50,Room 1523,MSC 8022, Bethesda, MD 20892 USA.
EM shanti.rabie@gmail.com
FU Intramural Research Program of NIAMS [NIH Z01 AR 41131]
FX The authors thank the Light Imaging Section of the Intramural Research
National Institute of Arthritis and Musculoskeletal and Skin Diseases,
and Dr. James A. Cooper for aid in confocal laser scanning microscopy
and scanning electron microscopy, respectively. This work is supported
by the Intramural Research Program of NIAMS (NIH Z01 AR 41131).
NR 43
TC 23
Z9 25
U1 0
U2 12
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
SN 0148-7043
J9 ANN PLAS SURG
JI Ann. Plast. Surg.
PD NOV
PY 2008
VL 61
IS 5
BP 566
EP 571
DI 10.1097/SAP.0b013e31816d9579
PG 6
WC Surgery
SC Surgery
GA 364VP
UT WOS:000260363800022
PM 18948788
ER
PT J
AU Drusano, GL
Okusanya, OO
Okusanya, A
Van Scoy, B
Brown, DL
Kulawy, R
Soergel, F
Heine, HS
Louie, A
AF Drusano, G. L.
Okusanya, Olanrewaju O.
Okusanya, Adedoyin
Van Scoy, Brian
Brown, D. L.
Kulawy, Robert
Soergel, Fritz
Heine, Henry S.
Louie, Arnold
TI Is 60 Days of Ciprofloxacin Administration Necessary for Postexposure
Prophylaxis for Bacillus anthracis?
SO ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
LA English
DT Article
ID NEW-YORK-CITY; ANTIBIOTIC-PROPHYLAXIS
AB Sixty days of ciprofloxacin administration at 500 mg every 12 h is currently recommended for the prophylaxis of inhalational exposure to Bacillus anthracis. We examined Bacillus anthracis (Delta-Sterne strain) in our hollow-fiber infection model. We measured the ciprofloxacin concentrations achieved and the number of organisms present before heat shock ( total population) and after heat shock ( spore population). We fit a mathematical model to these data. Monte Carlo simulation with differing initial spore burdens (3, 5, and 6.9 log(10) CFU/ml) demonstrated that 35 days of this regimen would completely clear the spore burden in 95% of patients. Durations of 110 days did not achieve 99.9% eradication, irrespective of initial burden, because of between-patient variance in drug pharmacokinetics. Given the absence of person-to-person transmission for Bacillus anthracis, adverse drug effects with long-term ciprofloxacin administration, and the possibility of engendering resistance in bodily flora, shorter prophylaxis duration should be given consideration, along with careful monitoring of all exposed individuals.
C1 [Drusano, G. L.; Okusanya, Adedoyin; Van Scoy, Brian; Brown, D. L.; Kulawy, Robert; Louie, Arnold] Ordway Res Inst, Lab Emerging Infect, Albany, NY 12208 USA.
[Okusanya, Olanrewaju O.] Ordway Res Inst, Inst Clin Pharmacodynam, Albany, NY 12208 USA.
[Soergel, Fritz] Inst Biomed & Pharmaceut Res, Nurnberg, Germany.
[Heine, Henry S.] USA, Med Res Inst Infect Dis, Ft Detrick, MD 21702 USA.
RP Drusano, GL (reprint author), Ordway Res Inst, Lab Emerging Infect, 150 New Scotland Ave, Albany, NY 12208 USA.
EM Gdrusano@ordwayresearch.org
FU "Choosing Drug Doses for Biodefense Pathogens." [1 PO1 AI060908- 01A1]
FX This study was funded by 1 PO1 AI060908- 01A1, "Choosing Drug Doses for
Biodefense Pathogens."; All the authors state that they have no
conflicts of interest.
NR 13
TC 11
Z9 11
U1 0
U2 0
PU AMER SOC MICROBIOLOGY
PI WASHINGTON
PA 1752 N ST NW, WASHINGTON, DC 20036-2904 USA
SN 0066-4804
EI 1098-6596
J9 ANTIMICROB AGENTS CH
JI Antimicrob. Agents Chemother.
PD NOV
PY 2008
VL 52
IS 11
BP 3973
EP 3979
DI 10.1128/AAC.00453-08
PG 7
WC Microbiology; Pharmacology & Pharmacy
SC Microbiology; Pharmacology & Pharmacy
GA 363ZI
UT WOS:000260305600021
PM 18725437
ER
PT J
AU Brunye, TT
Taylor, HA
Rapp, DN
AF Brunye, Tad T.
Taylor, Holly A.
Rapp, David N.
TI Repetition and Dual Coding in Procedural Multimedia Presentations
SO APPLIED COGNITIVE PSYCHOLOGY
LA English
DT Article
ID COGNITIVE LOAD; ANNOTATED ILLUSTRATIONS; INSTRUCTIONAL-DESIGN; SEDUCTIVE
DETAILS; WORKING-MEMORY; TEXT; PICTURES; ADULTS
AB Students learned toy assembly sequences presented in Picture, text, or one of three multimedia formats, and completed order verification, recall, and object assembly tasks. Experiment I compared repetitious (i.e. dual format presentations each conveying similar information) with complementary (i.e. dual format presentations each conveying different information) Multimedia presentations. Repetitious, presentations appear to provide learning benefits as a function of their inherent redundancy: complementary presentations provide benefits as a result of users actively integrating Picture and text elements into a cohesive mental model. Experiment 2 compared repetitious With interleaved (i.e. assembly steps presented in alternating picture-text formats) multimedia presentations. Again. multimedia presentations led to overall learning advantages relative to single-format presentations. with an emphasis on both repetition and integrative working memory processes. Object assembly performance consistently demonstrated the utility of picture learning, with or without accompanying text. Results are considered relative to classic and contemporary learning theory. and inform educational design. Copyright (C) 2007 John Wiley & Son, Ltd.
C1 [Brunye, Tad T.; Taylor, Holly A.] Tufts Univ, Dept Psychol, Medford, MA 02155 USA.
[Brunye, Tad T.] USA, RDEC, Natick, MA USA.
[Rapp, David N.] Northwestern Univ, Sch Educ & Social Policy, Evanston, IL 60208 USA.
[Rapp, David N.] Northwestern Univ, Dept Psychol, Evanston, IL 60208 USA.
RP Brunye, TT (reprint author), Tufts Univ, Dept Psychol, 490 Boston Ave, Medford, MA 02155 USA.
EM tbruny01@tufts.edu
NR 35
TC 9
Z9 9
U1 2
U2 6
PU JOHN WILEY & SONS LTD
PI CHICHESTER
PA THE ATRIUM, SOUTHERN GATE, CHICHESTER PO19 8SQ, W SUSSEX, ENGLAND
SN 0888-4080
J9 APPL COGNITIVE PSYCH
JI Appl. Cogn. Psychol.
PD NOV
PY 2008
VL 22
IS 7
BP 877
EP 895
DI 10.1002/acp.1396
PG 19
WC Psychology, Experimental
SC Psychology
GA 381FT
UT WOS:000261521800002
ER
PT J
AU Seely, JF
Holland, GE
Hudson, LT
Henins, A
AF Seely, John F.
Holland, Glenn E.
Hudson, Lawrence T.
Henins, Albert
TI X-ray modulation transfer functions of photostimulable phosphor image
plates and scanners
SO APPLIED OPTICS
LA English
DT Article; Proceedings Paper
CT 1st North American Symposium, on Laser Induced Breakdown Spectroscopy
CY OCT 08-10, 2007
CL New Orleans, LA
SP Mississippi State Univ
ID CRYSTAL SPECTROMETER; TRANSMISSION; SYSTEMS; LASER
AB The modulation transfer functions of two types of photostimulable phosphor image plat were determined in the 10 keV to 50 keV x-ray energy range using a resolution test pattern with up to 10 line pairs per mm (LP/mm) and a wavelength dispersive x-ray spectrometer. Techniques were developed for correcting For the partial transmittance of the high energy x-rays through the lead bars of the resolution test pattern, and the modulation transfer function (MTF) was determined from the measured change in contrast with LP/mm values. The MTF was convolved with the slit function of the image plate scanner, and the resulting point spread functions (PSFs) were in good agreement with the observed shapes and widths of x-ray spectral lines and with the PSF derived from edge spread functions. The shapes and the full width at half-maximum (FWHM) values of the PSF curves of the Fuji Superior Resolution (SR) and Fuji Maximum Sensitivity (MS) image plate detectors, consisting of the image plate and the scanner, determined by the three methods gave consistent results: The SR PSF is Gaussian with 0.13 mm FWHM, and the MS PSF is Lorentzian with 0.19 mm FWHM. These techniques result in the accurate determination of the spatial resolution achievable using image plate and scanner combinations and enable the optimization of spatial resolution for x-ray spectroscopy and radiography (C) 2008 Optical Society of America
C1 [Seely, John F.] USA, Res Lab, Div Space Sci, Washington, DC 20375 USA.
[Holland, Glenn E.] SFA Inc, Crofton, MD 21114 USA.
[Hudson, Lawrence T.; Henins, Albert] Natl Inst Stand & Technol, Gaithersburg, MD 20899 USA.
RP Seely, JF (reprint author), USA, Res Lab, Div Space Sci, Washington, DC 20375 USA.
EM john.seely@nrl.navy.mil
NR 14
TC 15
Z9 16
U1 0
U2 3
PU OPTICAL SOC AMER
PI WASHINGTON
PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA
SN 1559-128X
EI 2155-3165
J9 APPL OPTICS
JI Appl. Optics
PD NOV 1
PY 2008
VL 47
IS 31
BP 5753
EP 5761
DI 10.1364/AO.47.005753
PG 9
WC Optics
SC Optics
GA 374AD
UT WOS:000261013700027
PM 19122716
ER
PT J
AU Nguyen, DT
Sheng, C
Thomas, J
Norwood, R
Kimball, B
Steeves, DM
Peyghambarian, N
AF Nguyen, Dan T.
Sheng, Chuanxiang
Thomas, Jayan
Norwood, Robert
Kimball, Brian
Steeves, Diane M.
Peyghambarian, Nasser
TI Observation of nonlinear transmission enhancement in cavities filled
with nonlinear organic materials
SO APPLIED OPTICS
LA English
DT Article; Proceedings Paper
CT 1st North American Symposium, on Laser Induced Breakdown Spectroscopy
CY OCT 08-10, 2007
CL New Orleans, LA
SP Mississippi State Univ
ID CARBON NANOTUBES; OPTICAL LIMITER; FABRY-PEROT; SEMICONDUCTORS;
BISTABILITY; PULSES
AB We show experimental and theoretical results for enhancement of nonlinear transmission (NT) in moderate finesse cavities filled with nonlinear organic materials (NLOM). Our design for enhancement of nonlinear transmission using micro NLOM cavities compared with reference samples of the same material show that single cavities can enhance the nonlinear response by a factor of 10 or greater under high-absorption conditions. Further enhancement can be achieved in multiple-cavity structures. Other advantages of the cavity structures for nonlinear transmission, such as a higher damage threshold and a broader NT band, are also discussed. Our initial experimental results show a threefold reduction in the nonlinear threshold fluence in a single cavity device compared directly to an identical sample without mirrors, in qualitative agreement With our calculations. (C) 2008 Optical Society of America
C1 [Nguyen, Dan T.; Sheng, Chuanxiang; Thomas, Jayan; Norwood, Robert; Peyghambarian, Nasser] Univ Arizona, Coll Opt Sci, Tucson, AZ 85721 USA.
[Kimball, Brian; Steeves, Diane M.] USA, Natick Soldier Res Dev & Engn Ctr, Natick, MA 01760 USA.
RP Nguyen, DT (reprint author), Univ Arizona, Coll Opt Sci, 1630 E Univ Blvd, Tucson, AZ 85721 USA.
EM dnguyen@optics.arizona.edu
OI Nguyen, Dan/0000-0002-5244-8304
NR 25
TC 5
Z9 5
U1 0
U2 7
PU OPTICAL SOC AMER
PI WASHINGTON
PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA
SN 1559-128X
EI 2155-3165
J9 APPL OPTICS
JI Appl. Optics
PD NOV 1
PY 2008
VL 47
IS 31
BP 5777
EP 5783
DI 10.1364/AO.47.005777
PG 7
WC Optics
SC Optics
GA 374AD
UT WOS:000261013700030
PM 19122719
ER
PT J
AU De Lucia, FC
Gottfried, JL
Munson, CA
Miziolek, AW
AF De Lucia, Frank C., Jr.
Gottfried, Jennifer L.
Munson, Chase A.
Miziolek, Andrzej W.
TI Multivariate analysis of standoff laser-induced breakdown spectroscopy
spectra for classification of explosive-containing residues
SO APPLIED OPTICS
LA English
DT Article; Proceedings Paper
CT 1st North American Symposium, on Laser Induced Breakdown Spectroscopy
CY OCT 08-10, 2007
CL New Orleans, LA
SP Mississippi State Univ
ID DISCRIMINANT-ANALYSIS; STRATEGIES; SENSOR
AB A technique being evaluated for standoff explosives detection is laser-induced breakdown spectroscopy (LIBS). LIBS is a real-time sensor technology that uses components that can be configured into a ruggedized standoff instrument. The U.S. Army Research Laboratory has been coupling standoff LIBS spectra with chemometrics for several years now in order to discriminate between explosives and nonexplosives. We have investigated the use of partial least squares discriminant analysis (PLS-DA) for explosives detection. We have extended our study of PLS-DA to more complex sample types, including binary mixtures, different types of explosives, and samples not included in the model. We demonstrate the importance of building the PLS-DA model by iteratively testing it against sample test sets. Independent test sets are used to test the robustness of the final model. (C) 2008 Optical Society of America
C1 [De Lucia, Frank C., Jr.; Gottfried, Jennifer L.; Munson, Chase A.; Miziolek, Andrzej W.] USA, Res Lab, AMSRD, ARL,WM,BD, Aberdeen Proving Ground, MD 21005 USA.
RP De Lucia, FC (reprint author), USA, Res Lab, AMSRD, ARL,WM,BD, Aberdeen Proving Ground, MD 21005 USA.
EM fdelucia@arl.army.mil
RI Gottfried, Jennifer/G-6333-2010; De Lucia, Frank/D-5630-2012; Munson,
Chase/H-1667-2012
NR 24
TC 72
Z9 73
U1 3
U2 21
PU OPTICAL SOC AMER
PI WASHINGTON
PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA
SN 1559-128X
EI 2155-3165
J9 APPL OPTICS
JI Appl. Optics
PD NOV 1
PY 2008
VL 47
IS 31
BP G112
EP G121
DI 10.1364/AO.47.00G112
PG 10
WC Optics
SC Optics
GA 374AD
UT WOS:000261013700016
PM 19122692
ER
PT J
AU McManus, CE
McMillan, NJ
Harmon, RS
Whitmore, RC
De Lucia, FC
Miziolek, AW
AF McManus, Catherine E.
McMillan, Nancy J.
Harmon, Russell S.
Whitmore, Robert C.
De Lucia, Frank C., Jr.
Miziolek, Andrzej W.
TI Use of laser induced breakdown spectroscopy in the determination of gem
provenance: beryls
SO APPLIED OPTICS
LA English
DT Article; Proceedings Paper
CT 1st North American Symposium, on Laser Induced Breakdown Spectroscopy
CY OCT 08-10, 2007
CL New Orleans, LA
SP Mississippi State Univ
ID LA-ICP-MS; PEGMATITES; MAINE; AREA
AB The provenance of gem stones has been of interest to geologists, gemologists, archeologists, and historians for centuries. Laser induced breakdown spectroscopy (LIBS) provides a minimally destructive tool for recording the rich chemical signatures of gem beryls (aquamarine, goshenite, heliodor, and morganite). Broadband LIBS spectra of 39 beryl (Be3Al2Si6O18) specimens from 11 pegmatite mines in New Hampshire, Connecticut, and Maine (USA) are used to assess the potential of using principal component analysis of LIBS spectra to determine specimen provenance. Using this technique, beryls from the three beryl-bearing zones in the Palermo #1 pegmatite (New Hampshire) can be recognized. However, the compositional variation within this single mine is comparable to that in beryls from all three states. Thus, a very large database with detailed location metadata will be required to routinely determine gem beryl provenance. (C) 2008 Optical Society of America
C1 [McManus, Catherine E.; McMillan, Nancy J.] New Mexico State Univ, Dept Geol Sci, Las Cruces, NM 88003 USA.
[Harmon, Russell S.] USA, Res Off, Div Environm Sci, Res Triangle Pk, NC 27709 USA.
[Whitmore, Robert C.] Palermo Min Inc, Weare, NH 03281 USA.
[De Lucia, Frank C., Jr.; Miziolek, Andrzej W.] USA, Res Lab, Weap & Mat Sci Directorate, Aberdeen Proving Ground, MD 21005 USA.
RP McManus, CE (reprint author), New Mexico State Univ, Dept Geol Sci, MSC 3AB, Las Cruces, NM 88003 USA.
EM katedowe@aol.com
RI De Lucia, Frank/D-5630-2012
NR 16
TC 19
Z9 19
U1 1
U2 7
PU OPTICAL SOC AMER
PI WASHINGTON
PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA
SN 1559-128X
EI 2155-3165
J9 APPL OPTICS
JI Appl. Optics
PD NOV 1
PY 2008
VL 47
IS 31
BP G72
EP G79
DI 10.1364/AO.47.000G72
PG 8
WC Optics
SC Optics
GA 374AD
UT WOS:000261013700011
PM 19122706
ER
PT J
AU Munson, CA
Gottfried, JL
Snyder, EG
De Lucia, FC
Gullett, B
Miziolek, AW
AF Munson, Chase A.
Gottfried, Jennifer L.
Snyder, Emily Gibb
De Lucia, Frank C., Jr.
Gullett, Brian
Miziolek, Andrzej W.
TI Detection of indoor biological hazards using the man-portable laser
induced breakdown spectrometer
SO APPLIED OPTICS
LA English
DT Article; Proceedings Paper
CT 1st North American Symposium, on Laser Induced Breakdown Spectroscopy
CY OCT 08-10, 2007
CL New Orleans, LA
SP Mississippi State Univ
ID SPECTROSCOPY; DISCRIMINATION; CLASSIFICATION; STRATEGIES; SURFACES;
SENSOR; SPORES; LIBS
AB The performance of a man-portable laser induced breakdown spectrometer was evaluated for the detection of biological powders on indoor office surfaces and wipe materials. Identification of pure unknown powders was performed by comparing against a library of spectra containing biological agent surrogates and confusant materials, such as dusts, diesel soot, natural and artificial sweeteners, and drink powders, using linear correlation analysis. Simple models constructed using a second technique, partial least squares discriminant analysis, successfully identified Bacillus subtilis (BG) spores on wipe materials and office surfaces. Furthermore, these models were able to identify BG on materials not used in the training of the model. (C) 2008 Optical Society of America
C1 [Munson, Chase A.; Gottfried, Jennifer L.; De Lucia, Frank C., Jr.; Miziolek, Andrzej W.] USA, Res Lab, AMSRD, ARL,WM,BD, Aberdeen Proving Ground, MD 21005 USA.
[Snyder, Emily Gibb] US EPA, Off Res & Dev, Natl Homeland Secur Res Ctr, Res Triangle Pk, NC 27711 USA.
[Gullett, Brian] US EPA, Off Res & Dev, Natl Risk Management Res Lab, Res Triangle Pk, NC 27711 USA.
RP Munson, CA (reprint author), USA, Res Lab, AMSRD, ARL,WM,BD, Aberdeen Proving Ground, MD 21005 USA.
EM cmunson@arl.army.mil
RI Gottfried, Jennifer/G-6333-2010; De Lucia, Frank/D-5630-2012; Munson,
Chase/H-1667-2012
NR 23
TC 23
Z9 23
U1 3
U2 10
PU OPTICAL SOC AMER
PI WASHINGTON
PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA
SN 1559-128X
EI 2155-3165
J9 APPL OPTICS
JI Appl. Optics
PD NOV 1
PY 2008
VL 47
IS 31
BP G48
EP G57
DI 10.1364/AO.47.000G48
PG 10
WC Optics
SC Optics
GA 374AD
UT WOS:000261013700008
PM 19122702
ER
PT J
AU Snyder, EG
Munson, CA
Gottfried, JL
De Lucia, FC
Gullett, B
Miziolek, A
AF Snyder, Emily Gibb
Munson, Chase A.
Gottfried, Jennifer L.
De Lucia, Frank C., Jr.
Gullett, Brian
Miziolek, Andrzej
TI Laser-induced breakdown spectroscopy for the classification of unknown
powders
SO APPLIED OPTICS
LA English
DT Article; Proceedings Paper
CT 1st North American Symposium, on Laser Induced Breakdown Spectroscopy
CY OCT 08-10, 2007
CL New Orleans, LA
SP Mississippi State Univ
ID INDUCED FLUORESCENCE; SPORES; STATISTICS; LIBS
AB Laser-induced breakdown spectroscopy (LIBS) was used to discern between two biological agent surrogates (Bacillus atrophaeus and ovalbumin) and potential interferent compounds (mold spores, humic acid, house dust, and Arizona road dust), Multiple linear regression and neural network analysis models were constructed by using B. atrophaeus and ovalbumin spectra, and limits of detection were calculated. Classification of the agent surrogates' LIBS spectra was attempted by using a neural network model. False negative rates of 0%, were observed for B. atrophaeus (100 colony forming units) spore spectra with the neural network model used for classification. (C) 2008 Optical Society of America
C1 [Snyder, Emily Gibb] US EPA, Off Res & Dev, Natl Homeland Secur Res Ctr, Res Triangle Pk, NC 27711 USA.
[Munson, Chase A.; Gottfried, Jennifer L.; De Lucia, Frank C., Jr.; Miziolek, Andrzej] USA, Res Lab, AMSRD, ARL,WM,BD, Aberdeen Proving Ground, MD 21005 USA.
[Gullett, Brian] US EPA, Off Res & Dev, Natl Risk Management Res Lab, Res Triangle Pk, NC 27711 USA.
RP Snyder, EG (reprint author), US EPA, Off Res & Dev, Natl Homeland Secur Res Ctr, E343-06,109 TW Alexander Dr, Res Triangle Pk, NC 27711 USA.
EM snyder.emily@epa.gov
RI Gottfried, Jennifer/G-6333-2010; De Lucia, Frank/D-5630-2012; Munson,
Chase/H-1667-2012
NR 26
TC 18
Z9 19
U1 1
U2 10
PU OPTICAL SOC AMER
PI WASHINGTON
PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA
SN 1559-128X
EI 2155-3165
J9 APPL OPTICS
JI Appl. Optics
PD NOV 1
PY 2008
VL 47
IS 31
BP G80
EP G87
DI 10.1364/AO.47.000G80
PG 8
WC Optics
SC Optics
GA 374AD
UT WOS:000261013700012
PM 19122707
ER
PT J
AU Singh, JP
Martin, MZ
Miziolek, AW
AF Singh, Jagdish P.
Martin, Madhavi Z.
Miziolek, Andrzej W.
TI North American Symposium on Laser-Induced Breakdown Spectroscopy:
introduction to the feature issue
SO APPLIED OPTICS
LA English
DT Editorial Material
AB This feature issue highlights the topics of the 2007 North American Symposium oil Laser-Induced Breakdown Spectroscopy (LIBS), which includes LIBS application to security and forensics, biomedical and environmental, liquid analysis, and fundamentals of LIBS, instrumentation and commercialization, fusion with LIBS, and new frontiers. (C) 2008 Optical Society of America
C1 [Singh, Jagdish P.] Mississippi State Univ, Inst Clean Energy Technol, Starkville, MS 39759 USA.
[Martin, Madhavi Z.] Oak Ridge Natl Lab, Oak Ridge, TN 37831 USA.
[Miziolek, Andrzej W.] USA, Res Lab, Aberdeen Proving Ground, MD 21005 USA.
RP Singh, JP (reprint author), Mississippi State Univ, Inst Clean Energy Technol, 205 Res Blvd, Starkville, MS 39759 USA.
EM singh@icet.msstate.edu
RI Martin, Madhavi/A-5268-2011
NR 0
TC 0
Z9 0
U1 1
U2 1
PU OPTICAL SOC AMER
PI WASHINGTON
PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 USA
SN 1559-128X
EI 2155-3165
J9 APPL OPTICS
JI Appl. Optics
PD NOV 1
PY 2008
VL 47
IS 31
BP LIBS1
EP LIBS1
DI 10.1364/AO.47.0LIBS1
PG 1
WC Optics
SC Optics
GA 374AD
UT WOS:000261013700001
ER
PT J
AU Lo, E
Fountain, AW
Ingram, J
AF Lo, Edisanter
Fountain, Augustus W., III
Ingram, John
TI Statistical Modeling of Spatial Distortion in Hyperspectral Calibration
SO APPLIED SPECTROSCOPY
LA English
DT Article
DE Spectral calibration; Hyperspectral imaging; Statistical modeling
ID INFORMATION
AB This paper describes a statistically based efficient algorithm for the laboratory spectral calibration of a low-resolution terrestrial hyperspectral imaging camera operating in the visible range. Didymium oxide is used as a wavelength standard. The observed periodic spatial distortion in the wavelength abscissa of the hypercube is removed automatically through statistical modeling and the calibration of the wavelength abscissa is determined using a numerical method. The performance and cost of this algorithm in removing the spatial distortion are assessed quantitatively.
C1 [Fountain, Augustus W., III] Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD 21010 USA.
[Lo, Edisanter] Susquehanna Univ, Dept Math Sci, Selinsgrove, PA 17870 USA.
[Ingram, John] US Mil Acad, Photon Res Ctr, West Point, NY 10996 USA.
RP Fountain, AW (reprint author), Edgewood Chem Biol Ctr, Aberdeen Proving Ground, MD 21010 USA.
EM augustus.w.fountain@us.army.mil
FU Anny Research Office; United States Military, Academy
FX This research was sponsored by Dr. Paul Wilson, ARDEC, Picatinny
Arsenal, NJ. The authors wish to graciously acknowledge additional
Support by the Anny Research Office and the United States Military,
Academy. Dr. Lo would like to thank the National Research Council and
their support of his Senior Post Doctorate fellowship at the United
States Military Academy.
NR 14
TC 0
Z9 0
U1 0
U2 3
PU SOC APPLIED SPECTROSCOPY
PI FREDERICK
PA 201B BROADWAY ST, FREDERICK, MD 21701 USA
SN 0003-7028
J9 APPL SPECTROSC
JI Appl. Spectrosc.
PD NOV
PY 2008
VL 62
IS 11
BP 1189
EP 1199
PG 11
WC Instruments & Instrumentation; Spectroscopy
SC Instruments & Instrumentation; Spectroscopy
GA 376QO
UT WOS:000261198300005
PM 19007459
ER
PT J
AU Darling, MJ
Bauer, A
AF Darling, Matthew J.
Bauer, Andrew
TI Picture of the Month - Denouement and Discussion - Osteoma Cutis
Associated With Pseudohypoparathyroidism Type 1a
SO ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE
LA English
DT Editorial Material
ID PROGRESSIVE OSSEOUS HETEROPLASIA; FIBRODYSPLASIA OSSIFICANS PROGRESSIVA;
HETEROTOPIC OSSIFICATION; HEREDITARY OSTEODYSTROPHY; GNAS1 GENE
C1 [Darling, Matthew J.; Bauer, Andrew] Walter Reed Army Med Ctr, Dept Pediat, Washington, DC 20307 USA.
[Bauer, Andrew] Uniformed Serv Univ Hlth Sci, Bethesda, MD USA.
RP Bauer, A (reprint author), Walter Reed Army Med Ctr, Dept Pediat, 6900 Georgia Ave, Washington, DC 20307 USA.
EM abauer@usuhs.mil
NR 12
TC 1
Z9 1
U1 0
U2 1
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 515 N STATE ST, CHICAGO, IL 60654-0946 USA
SN 1072-4710
J9 ARCH PEDIAT ADOL MED
JI Arch. Pediatr. Adolesc. Med.
PD NOV
PY 2008
VL 162
IS 11
BP 1091
EP 1092
DI 10.1001/archpedi.162.11.1091
PG 2
WC Pediatrics
SC Pediatrics
GA 368DD
UT WOS:000260600600014
PM 18981359
ER
PT J
AU Brose, SW
Boninger, ML
Fullerton, B
McCann, T
Collinger, JL
Impink, BG
Dyson-Hudson, TA
AF Brose, Steven W.
Boninger, Michael L.
Fullerton, Bradley
McCann, Thane
Collinger, Jennifer L.
Impink, Bradley G.
Dyson-Hudson, Trevor A.
TI Shoulder Ultrasound Abnormalities, Physical Examination Findings, and
Pain in Manual Wheelchair Users With Spinal Cord Injury
SO ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
LA English
DT Article
DE Rehabilitation; Shoulder; Spinal cord injuries; Ultrasonography;
Wheelchairs
ID ROTATOR CUFF TEARS; IMPINGEMENT SYNDROME; SUBACROMIAL BURSA; UPPER
EXTREMITY; LABRAL TEARS; TENDON TEARS; INDEX WUSPI; DIAGNOSIS;
ULTRASONOGRAPHY; INDIVIDUALS
AB Objectives: To investigate the presence of ultrasound (US) abnormalities in manual wheelchair users with spinal cord injury (SCI) using a quantitative Ultrasound Shoulder Pathology Rating Scale (USPRS). To investigate physical examination (PE) findings using a quantitative Physical Examination of the Shoulder Scale (PESS), and to obtain data about pain and other subject characteristics such as age, years with SCI, and weight.
Design: Case series.
Setting: National Veterans' Wheelchair Games 2005 and 2006.
Participants: Volunteer sample of manual wheelchair users with SCI participating in the National Veterans' Wheelchair Games. Interventions: Not applicable.
Main Outcome Measures: Presence of relationships between US findings, PE findings, pain, and subject characteristics.
Results: The USPRS correlated with age, duration of SCI, and weight (all P <.01), and showed a positive trend with the total Wheelchair User's Shoulder Pain Index (WUSPI) score (r=.258, P=.073). Several US findings related to presence of PE findings for specific structures. The PESS score correlated with the WUSPI (r=.679, P <.001) and duration of SCI (P <.05). The presence of untreated shoulder pain that curtailed activity was noted in 24.5% of subjects, and this was related to increased WUSPI scores (P=.002).
Conclusions: PE and US abnormalities are common in manual wheelchair users with SCL The USPRS and PESS demonstrated evidence for external validity and hold promise as research tools. Untreated shoulder pain is common in manual wheelchair users with SCI, and further investigation of this pain is indicated.
C1 [Brose, Steven W.; Boninger, Michael L.; Collinger, Jennifer L.] Univ Pittsburgh, Med Ctr, Dept Phys Med & Rehabil, Pittsburgh, PA 15213 USA.
[Boninger, Michael L.; Collinger, Jennifer L.; Impink, Bradley G.] Vet Affairs Pittsburgh Healthcare Syst, Human Engn Res Labs, Pittsburgh, PA USA.
[Fullerton, Bradley] Patient Phys Partnership, Austin, TX USA.
[Fullerton, Bradley] Childrens Hosp Austin, Austin, TX USA.
[McCann, Thane] Walter Reed Army Med Ctr, Dept Orthopaed & Rehabil, Washington, DC 20307 USA.
[McCann, Thane] Thomas Jefferson Univ, Philadelphia, PA 19107 USA.
[Dyson-Hudson, Trevor A.] Kessler Med Rehabil Res & Educ Ctr, W Orange, NJ USA.
[Dyson-Hudson, Trevor A.] Univ Med & Dent New Jersey, Dept Phys Med & Rehabil, Sch Med, Newark, NJ 07103 USA.
RP Brose, SW (reprint author), Univ Pittsburgh, Med Ctr, Dept Phys Med & Rehabil, 3471 5th Ave,Ste 201, Pittsburgh, PA 15213 USA.
EM brosesw@upmc.edu
OI Boninger, Michael/0000-0001-6966-919X
FU Veterans Affairs Center of Excellence for Wheelchairs; Associated
Rehabilitation [B3142C]; National Science Foundation [DGE0333420];
National Institute on Disability and Rehabilitation [H133N000019];
Paralyzed Veterans of America
FX Supported by the Veterans Affairs Center of Excellence for Wheelchairs
and Associated Rehabilitation (grant no. B3142C), the National Science
Foundation (grant no. DGE0333420), the National Institute on Disability
and Rehabilitation (grant no. H133N000019), and the Paralyzed Veterans
of America.
NR 44
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U1 1
U2 5
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0003-9993
J9 ARCH PHYS MED REHAB
JI Arch. Phys. Med. Rehabil.
PD NOV
PY 2008
VL 89
IS 11
BP 2086
EP 2093
DI 10.1016/j.apmr.2008.05.015
PG 8
WC Rehabilitation; Sport Sciences
SC Rehabilitation; Sport Sciences
GA 373PY
UT WOS:000260985600006
PM 18996236
ER
PT J
AU Pirooznia, M
Habib, T
Perkins, EJ
Deng, Y
AF Pirooznia, Mehdi
Habib, Tanwir
Perkins, Edward J.
Deng, Youping
TI GOfetcher: a database with complex searching facility for gene ontology
SO BIOINFORMATICS
LA English
DT Article
ID ANNOTATION; TOOL
AB Motivation: An important contribution to the Gene Ontology (GO) project is to develop tools that facilitate the creation, maintenance and use of ontologies. Several tools have been created for communicating and using the GO project. However, a limitation with most of these tools is that they suffer from lack of a comprehensive search facility. We developed a web application, GOfetcher, with a very comprehensive search facility for the GO project and a variety of output formats for the results. GOfetcher has three different levels for searching the GO: Quick Search, Advanced Search and Upload Files for searching. The application includes a unique search option which generates gene information given a nucleotide or protein accession number which can then be used in generating GO information. The output data in GOfetcher can be saved into several different formats; including spreadsheet, comma-separated values and the extensible markup language (XML) format. The database is available at http://mcbc.usm.edu/gofetcher/.
C1 [Pirooznia, Mehdi; Habib, Tanwir; Deng, Youping] Univ So Mississippi, Dept Biol Sci, Hattiesburg, MS 39406 USA.
[Perkins, Edward J.] USA, Ctr Res Dev & Engn, Environm Lab, Vicksburg, MS 39180 USA.
RP Pirooznia, M (reprint author), Univ So Mississippi, Dept Biol Sci, Hattiesburg, MS 39406 USA.
OI Pirooznia, Mehdi/0000-0002-4210-6458
FU Mississippi Functional Genomics Networks and Mississippi Computational
Biology Consortium (NSF) [EPS-0556308]; US Army Environmental Quality
Program [W912HZ-05-P-0145]
FX Funding: Mississippi Functional Genomics Networks and Mississippi
Computational Biology Consortium (NSF Grant # EPS-0556308); US Army
Environmental Quality Program (contract # W912HZ-05-P-0145).
NR 8
TC 8
Z9 8
U1 0
U2 1
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1367-4803
J9 BIOINFORMATICS
JI Bioinformatics
PD NOV 1
PY 2008
VL 24
IS 21
BP 2561
EP 2563
DI 10.1093/bioinformatics/btn441
PG 3
WC Biochemical Research Methods; Biotechnology & Applied Microbiology;
Computer Science, Interdisciplinary Applications; Mathematical &
Computational Biology; Statistics & Probability
SC Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology;
Computer Science; Mathematical & Computational Biology; Mathematics
GA 365BP
UT WOS:000260381200028
PM 18728045
ER
PT J
AU Wu, HX
Bynum, JA
Stavchansky, S
Bowman, PD
AF Wu, Haoxiang
Bynum, James A.
Stavchansky, Salomon
Bowman, Phillip D.
TI Reuse of cDNA microarrays hybridized with cRNA by stripping with RNase H
SO BIOTECHNIQUES
LA English
DT Article
ID REPRODUCIBILITY
AB DNA microarrays are powerful tools for global analysis of gene transcript expression. However their high cost and the need for replication have limited their use. Here, we report a new stripping technique applicable to microarrays hybridized with cRNA with RNase H that is reproducible, leaving the DNA oligonucleotide probes intact and available for adding two additional uses. A Pearson correlation was used to assess the agreement between the first-round hybridization and the second- and third-round hybridizations. Significant cord relations (R(2), 0.9893 and 0.975: P < 0.001) were observed among virgin arrays and stripped arrays hybridized with the same sample. Additionally, statistical class comparison analysis globally indicated that there were essentially no differences detected following three hybridizations. Dye-swapped microarrays produced similar results. However arrays stripped with RNase H exhibited decreased efficiency, of hybridization signal with increasing use. In the present study, the oligonucleotide microarrays can be used three times.
C1 [Wu, Haoxiang; Bynum, James A.; Bowman, Phillip D.] USA, Inst Surg Res, San Antonio, TX USA.
[Wu, Haoxiang; Stavchansky, Salomon] Univ Texas Austin, Coll Pharm, Austin, TX 78712 USA.
RP Bowman, PD (reprint author), USA, Inst Surg Res, 3400 Rawley E Chambers Ave,Bldg 3611, Ft Sam Houston, TX 78234 USA.
EM phillip.bowman@amedd.army.mil
FU U.S. Army Medical Research and Material Command
FX The U.S. Army Medical Research and Material Command is gratefully
acknowledged for funding this research. The opinions or assertions
contained herein are the private views of the authors and are not to be
construed as official or as reflecting the views of the Department of
the Army or the Department of Defense.
NR 7
TC 3
Z9 3
U1 0
U2 0
PU INFORMA HEALTHCARE
PI NEW YORK
PA 52 VANDERBILT AVE, NEW YORK, NY 10017 USA
SN 0736-6205
J9 BIOTECHNIQUES
JI Biotechniques
PD NOV
PY 2008
VL 45
IS 5
BP 573
EP 575
DI 10.2144/000112952
PG 3
WC Biochemical Research Methods; Biochemistry & Molecular Biology
SC Biochemistry & Molecular Biology
GA 411GL
UT WOS:000263637200008
PM 19007341
ER
PT J
AU Figueroa, JD
Sakoda, LC
Graubard, BI
Chanock, S
Rubertone, MV
Erickson, RL
McGlynn, KA
AF Figueroa, Jonine D.
Sakoda, Lori C.
Graubard, Barry I.
Chanock, Stephen
Rubertone, Mark V.
Erickson, R. Loren
McGlynn, Katherine A.
TI Genetic variation in hormone metabolizing genes and risk of testicular
germ cell tumors
SO CANCER CAUSES & CONTROL
LA English
DT Article
DE testicular cancer; hormone metabolism; genetic polymorphisms
ID BREAST-CANCER RISK; POLYCHLORINATED-BIPHENYLS; ANDROGEN RECEPTOR; CYP1A1
POLYMORPHISMS; CYTOCHROME-P450 1A1; HSD17B1 GENE; IN-UTERO; ESTROGEN;
WOMEN; EXPOSURE
AB Testicular germ cell tumors (TGCT) that arise in young men are composed of two histologic types, seminomas and nonseminomas. Risk patterns for the two types appear to be similar and may be related to either endogenous or exogenous hormonal exposures in utero. Why similar risk patterns would result in different histologic types is unclear, but could be related to varying genetic susceptibility profiles. Genetic variation in hormone metabolizing genes could potentially modify hormonal exposures, and thereby affect which histologic type a man develops. To examine this hypothesis, 33 single nucleotide polymorphisms (SNPs) in four hormone metabolism candidate genes (CYP1A1, CYP17A1, HSD17B1, HSD17B4) and the androgen receptor gene (AR) were genotyped. Associations with TGCT were evaluated among 577 TGCT cases (254 seminoma, 323 nonseminoma) and 707 controls from the US Servicemen's Testicular Tumor Environmental and Endocrine Determinants (STEED) study. There were no significant associations with TGCT overall based on a test using an additive model. However, compared to homozygotes of the most common allele, two nonredundant SNPs in CYP1A1 were inversely associated with nonseminoma: CYP1A1 promoter SNP rs4886605 OR = 0.75 (95% CI = 0.54-1.04) among the heterozygotes and OR = 0.37, 95% CI = 0.12-1.11 among the homozygotes with a p-value for trend = 0.02; rs2606345 intron 1 SNP, OR = 0.69 (95% CI = 0.51-0.93) among heterozygotes and OR = 0.70 (95% CI = 0.42-1.17) among homozygotes, with a p-value for trend = 0.02. Caution in interpretation is warranted until findings are replicated in other studies; however, the results suggest that genetic variation in CYP1A1 may be associated with nonseminoma.
C1 [Figueroa, Jonine D.; Graubard, Barry I.; Chanock, Stephen; McGlynn, Katherine A.] NCI, Dept Hlth & Human Serv, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
[Figueroa, Jonine D.] NCI, Canc Prevent Fellowship Program, Off Prevent Oncol, NIH, Bethesda, MD 20892 USA.
[Sakoda, Lori C.] Univ Washington, Dept Epidemiol, Sch Publ Hlth & Community Med, Seattle, WA 98195 USA.
[Chanock, Stephen] NCI, Dept Hlth & Human Serv, Core Genotyping Facil, Adv Technol Ctr, Bethesda, MD 20892 USA.
[Rubertone, Mark V.] USA, Ctr Hlth Promot & Prevent Med, Silver Spring, MD USA.
[Erickson, R. Loren] Walter Reed Army Inst Res, Global Emerging Infect Syst, Silver Spring, MD USA.
RP Figueroa, JD (reprint author), NCI, Dept Hlth & Human Serv, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
EM figueroaj@mail.nih.gov
FU NCI Cancer Prevention Fellowship program
FX The authors wish to thank Emily Steplowski of IMS for her contributions
to data management and Sabah Quraishi for her contributions to data
analysis. In addition, Jonine Figueroa would like to thank Victoria Chia
and Michael Cook for discussions about data presentation and the NCI
Cancer Prevention Fellowship program for their support. The opinions or
assertions contained herein are the private views of the authors and are
not to be construed as official or as reflecting the views of the
Department of the Army or the Department of Defense.
NR 60
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U1 1
U2 3
PU SPRINGER
PI DORDRECHT
PA VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
SN 0957-5243
J9 CANCER CAUSE CONTROL
JI Cancer Causes Control
PD NOV
PY 2008
VL 19
IS 9
BP 917
EP 929
DI 10.1007/s10552-008-9153-6
PG 13
WC Oncology; Public, Environmental & Occupational Health
SC Oncology; Public, Environmental & Occupational Health
GA 351WR
UT WOS:000259457100003
PM 18415690
ER
PT J
AU Collen, J
Greenburg, D
Holley, A
King, CS
Hnatiuk, O
AF Collen, Jacob
Greenburg, David
Holley, Aaron
King, Christopher S.
Hnatiuk, Oleh
TI Discordance in Spirometric Interpretations Using Three Commonly Used
Reference Equations vs National Health and Nutrition Examination Study
III
SO CHEST
LA English
DT Article
DE airways; pulmonary function test; spirometry
ID FLOW-VOLUME CURVE; PULMONARY-FUNCTION; UNITED-STATES; LUNG; OBSTRUCTION;
MANAGEMENT; STANDARDS; VALUES; ADULTS; AGE
AB Background: Spirometry plays an essential role in the diagnosis and management of pulmonary diseases. The accurate interpretation of spirometric data depends on comparison to a reference population to identify abnormalities in ventilatory function. National guidelines recommended the use of the National Health and Nutrition Examination Study (NHANES) III data set as the preferred reference population for those persons 8 to 80 years of age in the United States. Objectives: To determine the effect of using NHANES III reference equations, compared to those of Crapo et al (Crapo), Knudson et al (Knudson), or Morris et al (Morris), on spirometric interpretations in non-Hispanic white patients.
Methods: We conducted a cross-sectional study of all white patients undergoing spirometry testing at our hospital from January 2000 through May 2007. Patients were classified as normal, restricted, obstructed, or mixed, based on the American Thoracic Society (ATS)/European Respiratory Society (ERS) guidelines, using the Crapo, Knudson, Morris, and NHANES III prediction equations. Differences in the classifications based on the reference data set were evaluated.
Results: At total of 8,733 subjects (62.4% male subjects) were identified, with a mean age of 53 years. Discordance was most common when the results from prediction equations by Knudson and Mortis were compared to those of NHANES 111 (45.5% and 35.3%, respectively). Diagnostic recategorizations occurred less frequently when the prediction equations by Crapo were compared with those of NHANES 111 (15.9%). Relative to NHANES 111, the prediction equations by Knudson, Crapo, and Morris tend to overclassify obstruction and underclassify restriction.
Conclusions: There is significant discordance between the prediction equations put forth by Crapo, Knudson, Morris, and the NHANES III. Our data suggest that the diagnostic reclassification of many patients undergoing pulmonary function testing will occur when ATS/ERS guidelines are implemented. Pulmonologists and other physicians interpreting spirometry need to be aware of the presence and nature of these changes. (CHEST 2008; 134:1009-1016)
C1 [Collen, Jacob; Greenburg, David] Walter Reed Army Med Ctr, Dept Internal Med, Washington, DC 20350 USA.
[Holley, Aaron; King, Christopher S.; Hnatiuk, Oleh] Walter Reed Army Med Ctr, Dept Pulm Crit Care Med, Washington, DC 20350 USA.
RP King, CS (reprint author), Walter Reed Army Med Ctr, Dept Med, 6900 Georgia Ave NW, Washington, DC 20350 USA.
EM christopher.king@na.amedd.army.mil
RI Osborne, Nicholas/N-4915-2015
OI Osborne, Nicholas/0000-0002-6700-2284
NR 21
TC 25
Z9 25
U1 0
U2 1
PU AMER COLL CHEST PHYSICIANS
PI NORTHBROOK
PA 3300 DUNDEE ROAD, NORTHBROOK, IL 60062-2348 USA
SN 0012-3692
J9 CHEST
JI Chest
PD NOV
PY 2008
VL 134
IS 5
BP 1009
EP 1016
DI 10.1378/chest.08-0614
PG 8
WC Critical Care Medicine; Respiratory System
SC General & Internal Medicine; Respiratory System
GA 372RF
UT WOS:000260918500020
PM 18988777
ER
PT J
AU Welch, CR
Marcuson, WF
Adiguzel, I
AF Welch, Charles R.
Marcuson, William F., III
Adiguzel, Ilker
TI Will Supermolecules and Supercomputers Lead to Super Construction
Materials?
SO CIVIL ENGINEERING
LA English
DT Article
C1 [Welch, Charles R.] USA, ERDC, Shock & Vibrat Informat Anal Ctr, Washington, DC USA.
RP Welch, CR (reprint author), USA, ERDC, Shock & Vibrat Informat Anal Ctr, Washington, DC USA.
NR 0
TC 1
Z9 1
U1 0
U2 1
PU ASCE-AMER SOC CIVIL ENGINEERS
PI RESTON
PA 1801 ALEXANDER BELL DR, RESTON, VA 20191-4400 USA
SN 0885-7024
J9 CIVIL ENG
JI Civil Eng.
PD NOV
PY 2008
VL 78
IS 11
BP 42
EP 52
PG 11
WC Engineering, Civil
SC Engineering
GA 369NS
UT WOS:000260701800015
ER
EF